The interplay of sociodemographic factors on virologic suppression among a U.S. outpatient HIV clinic population.
Understanding challenges to virologic suppression is essential to optimizing health outcomes among individuals with HIV. This cross-sectional behavioral assessment was conducted among 514 individuals presenting at an urban U.S. HIV clinic between June and September 2007. The majority of the sample was African American and male, with a mean age of 42 years. Most of the sample was receiving highly active antiretroviral therapy (HAART), and the majority of those had suppressed viral loads (HIV viral loads less than 400 copies per milliliter). By logistic regression analyses, African American/other minorities had 2.9 increased odds, those less than high school degree had 2.3 increased odds, those who were receiving ritonavir-boosted protease inhibitor therapy had 1.4 increased odds, and those who had expressed symptoms indicative of depressive disorders had 2.5 increased odds of having unsuppressed viremia as compared to Caucasians, those with more education, receiving non-nucleoside reverse transcriptase inhibitor-based therapy, and who had minimal depressive symptoms, respectively. These findings signify the importance of individualized interventions to enhance virologic suppression, both based on medication choices and individual characteristics.
Shacham
Enbal
E
Health Communication Research Laboratory, George Warren Brown School of Social Work, Washington University, St. Louis, Missouri 63112-1408, USA. eshacham@wustl.edu
Nurutdinova
Diana
D
Onen
Nur
N
Stamm
Katelin
K
Overton
E Turner
ET
D000293:Adolescent; D000328:Adult; D000554:Ambulatory Care Facilities; D019380:Anti-HIV Agents / Q000494:pharmacology / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000191:economics / Q000208:ethnology / Q000821:virology*; D015497:HIV-1 / Q000187:drug effects*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008923:Missouri; D010349:Patient Compliance; D012307:Risk Factors; D012923:Social Class; D012959:Socioeconomic Factors; D014505:Urban Population; D019562:Viral Load; D014766:Viremia / Q000188:drug therapy* / Q000821:virology; D055815:Young Adult
D019380:Anti-HIV Agents
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