Beta-thalassemia intermedia associated with moyamoya syndrome.
Moyamoya syndrome (MMS) is a progressive disorder. We report a 19-year-old boy with beta-thalassemia who presented with a left hemiparesis. Brain MRI showed old middle cerebral artery and left frontal subcortical white matter infarcts. Brain magnetic resonance angiography and digital subtraction angiography revealed occlusion of the bilateral internal carotid arteries with a rich network of basal collateral vessels. To our knowledge this is the third report of beta-thalassemia intermedia and MMS, and the first report of a patient in Turkey. It emphasizes the potential for cerebral infarct due to anemia, protein S and thrombocytosis.
Göksel
Basak Karakurum
BK
Department of Neurology, Faculty of Medicine, Adana Teaching and Medical Research Center, Baskent University, Dadaloglu Mah., 39 Sok No. 6, Yuregir, Adana, Turkey. bkarakurum@hotmail.com
Ozdogu
Hakan
H
Yildirim
Tulin
T
Oğuzkurt
Levent
L
Asma
Suheyl
S
D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000150:complications* / Q000175:diagnosis*; D055815:Young Adult; D017086:beta-Thalassemia / Q000150:complications* / Q000175:diagnosis*