The assessment of disability related to vision performance-based measure in diabetic retinopathy.
OBJECTIVE
To validate a third-generation performance-based measure of visual function titled "Assessment of Disability Related to Vision" (ADREV) in a study population of patients with diabetic retinopathy.


METHODS
Prospective, cross-sectional study.


METHODS
Patients with nonproliferative or proliferative diabetic retinopathy, free from ocular comorbidity, were recruited from a single institute and completed the ADREV, the 25-Item National Eye Institute Visual Functioning Questionnaire (VFQ-25), and a clinical ophthalmic examination. Correlation, regression, and bootstrap analysis were conducted to determine the relationship between ADREV scoring and each of the study's clinical and self-report measures of visual ability, while controlling for potential confounders.


RESULTS
Ninety-one patients with diabetic retinopathy completed the study and analysis showed that the ADREV total and subscale scores shared a stronger relationship with the clinical measures of visual function than did the VFQ total and subscale scores. Regression analysis revealed that binocular visual acuity, contrast sensitivity, and better eye visual field were the best predictors of ADREV performance.


CONCLUSIONS
The ADREV performance measure is a valid instrument for the assessment of disability related to vision in patients with diabetic retinopathy. Furthermore, the assessments provided by ADREV were more related to traditional clinical indicators of visual impairment than were the results of the self-report measure, specifically the VFQ-25.
Warrian
Kevin J
KJ
Glaucoma Research Center, William and Anna Goldberg Glaucoma Service, Wills Eye Institute, Philadelphia, Pennsylvania, USA. kevinjwarrian@gmail.com
Lorenzana
Luciano L
LL
Lankaranian
Dara
D
Dugar
Jyoti
J
Wizov
Sheryl S
SS
Spaeth
George L
GL
D015897:Comorbidity; D015350:Contrast Sensitivity / Q000502:physiology; D003430:Cross-Sectional Studies; D003930:Diabetic Retinopathy / Q000175:diagnosis*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000175:diagnosis*; D015348:Vision, Binocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology; D019987:Persons with Visual Disabilities