title: [Two cases of esophageal achalasia, in which localized botulinum toxin injections were effective to improve symptoms].
abstract: The cases were a 64-year-old man and a 57-year-old woman both with discomfort and dysphasia. They were given a diagnosis of esophageal achalasia after gastrointestinal endoscopy, barium esophagography and esophageal internal pressure tests. Their symptoms were dramatically improved by localized botulinum toxin injections, which were commonly available in the US. The localized botulinum toxin injection treatment is safe and minimally invasive with few complications. It is effective to reduce symptoms in esophageal achalasia.
authors.affiliation: Department of Internal Medicine, Saga University of Medical Sciences, , Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Tominaga
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Iwakiri
authors.forename: Nanae
authors.initials: N
authors.lastname: Tsuruoka
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakayama
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Arima
authors.forename: Kotaro
authors.initials: K
authors.lastname: Mannen
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Sakata
authors.forename: Ryo
authors.initials: R
authors.lastname: Shimoda
authors.forename: Seiji
authors.initials: S
authors.lastname: Tsunada
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sakata
authors.forename: Kazuma
authors.initials: K
authors.lastname: Fujimoto
mesh_terms: D001905:Botulinum Toxins / Q000008:administration & dosage*; D004931:Esophageal Achalasia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged
chemical_list: D001905:Botulinum Toxins