title: Out-FOX(O)ing proteolysis in sepsis.
authors.affiliation: Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada. phillis@mcmaster.ca
authors.forename: Stuart M
authors.initials: SM
authors.lastname: Phillips
mesh_terms: D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D051858:Forkhead Transcription Factors / Q000378:metabolism*; D005938:Glucocorticoids / Q000494:pharmacology / Q000627:therapeutic use; D015850:Interleukin-6 / Q000378:metabolism; D009124:Muscle Proteins / Q000187:drug effects / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D051381:Rats; D018805:Sepsis / Q000150:complications / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D019282:Wasting Syndrome / Q000209:etiology / Q000378:metabolism* / Q000517:prevention & control; D000071161:Forkhead Box Protein O1
chemical_list: D003907:Dexamethasone; D051858:Forkhead Transcription Factors; D005938:Glucocorticoids; D015850:Interleukin-6; D009124:Muscle Proteins; D009419:Nerve Tissue Proteins; D011494:Protein Kinases; D051057:Proto-Oncogene Proteins c-akt; D014409:Tumor Necrosis Factor-alpha; C074639:Foxo1 protein, rat; D000071161:Forkhead Box Protein O1; C403287:pyruvate dehydrogenase kinase 4
references.citation: J Physiol. 2010 Apr 15;588(Pt 8):1333-47
references.pmid: 20176631
references.citation: FASEB J. 2004 Jan;18(1):39-51
references.pmid: 14718385
references.citation: J Physiol. 2009 Dec 1;587(Pt 23):5559-68
references.pmid: 19752112
references.citation: J Appl Physiol (1985). 2007 Jul;103(1):378-87
references.pmid: 17332274
references.citation: J Physiol. 2002 Dec 15;545(3):819-28
references.pmid: 12482888
references.citation: JAMA. 2009 Jun 10;301(22):2362-75
references.pmid: 19509383
references.citation: J Physiol. 2008 Nov 15;586(22):5589-600
references.pmid: 18818241
references.citation: Curr Opin Support Palliat Care. 2007 Dec;1(4):287-92
references.pmid: 18685377
references.citation: Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L994-L1001
references.pmid: 19376888