title: The assessment of disability related to vision performance-based measure in diabetic retinopathy.
abstract: OBJECTIVE
  To validate a third-generation performance-based measure of visual function titled "Assessment of Disability Related to Vision" (ADREV) in a study population of patients with diabetic retinopathy.
  
  
  METHODS
  Prospective, cross-sectional study.
  
  
  METHODS
  Patients with nonproliferative or proliferative diabetic retinopathy, free from ocular comorbidity, were recruited from a single institute and completed the ADREV, the 25-Item National Eye Institute Visual Functioning Questionnaire (VFQ-25), and a clinical ophthalmic examination. Correlation, regression, and bootstrap analysis were conducted to determine the relationship between ADREV scoring and each of the study's clinical and self-report measures of visual ability, while controlling for potential confounders.
  
  
  RESULTS
  Ninety-one patients with diabetic retinopathy completed the study and analysis showed that the ADREV total and subscale scores shared a stronger relationship with the clinical measures of visual function than did the VFQ total and subscale scores. Regression analysis revealed that binocular visual acuity, contrast sensitivity, and better eye visual field were the best predictors of ADREV performance.
  
  
  CONCLUSIONS
  The ADREV performance measure is a valid instrument for the assessment of disability related to vision in patients with diabetic retinopathy. Furthermore, the assessments provided by ADREV were more related to traditional clinical indicators of visual impairment than were the results of the self-report measure, specifically the VFQ-25.
authors.affiliation: Glaucoma Research Center, William and Anna Goldberg Glaucoma Service, Wills Eye Institute, Philadelphia, Pennsylvania, USA. kevinjwarrian@gmail.com
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Warrian
authors.forename: Luciano L
authors.initials: LL
authors.lastname: Lorenzana
authors.forename: Dara
authors.initials: D
authors.lastname: Lankaranian
authors.forename: Jyoti
authors.initials: J
authors.lastname: Dugar
authors.forename: Sheryl S
authors.initials: SS
authors.lastname: Wizov
authors.forename: George L
authors.initials: GL
authors.lastname: Spaeth
mesh_terms: D015897:Comorbidity; D015350:Contrast Sensitivity / Q000502:physiology; D003430:Cross-Sectional Studies; D003930:Diabetic Retinopathy / Q000175:diagnosis*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000175:diagnosis*; D015348:Vision, Binocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology; D019987:Persons with Visual Disabilities