Vive les differences! Individual variation in neural mechanisms of executive control.
Investigations of individual differences have become increasingly important in the cognitive neuroscience of executive control. For instance, individual variation in lateral prefrontal cortex function (and that of associated regions) has recently been used to identify contributions of executive control processes to a number of domains, including working memory capacity, anxiety, reward/motivation, and emotion regulation. However, the origins of such individual differences remain poorly understood. Recent progress toward identifying the genetic and environmental sources of variation in neural traits, in combination with progress in identifying the causal relationships between neural and cognitive processes, will be essential for developing a mechanistic understanding of executive control.
Braver
Todd S
TS
Department of Psychology, Washington University in St. Louis, St. Louis, MO, USA. tbraver@artsci.wustl.edu
Cole
Michael W
MW
Yarkoni
Tal
T
D000818:Animals; D001007:Anxiety / Q000235:genetics; D001288:Attention / Q000502:physiology; D001921:Brain / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D004644:Emotions / Q000502:physiology; D056344:Executive Function / Q000502:physiology*; D014644:Genetic Variation / Q000502:physiology*; D006801:Humans; D008570:Memory, Short-Term / Q000502:physiology; D009042:Motivation / Q000235:genetics
Hum Brain Mapp. 2009 Oct;30(10):3127-41
19235882
J Cogn Neurosci. 2008 Nov;20(11):1980-92
18416677
Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16841-6
19805383
J Exp Psychol Gen. 2008 May;137(2):201-225
18473654
Neuron. 2008 Sep 25;59(6):1037-50
18817740
Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6802-7
19339493
Cogn Affect Behav Neurosci. 2008 Sep;8(3):239-53
18814461
Biol Psychiatry. 2002 Oct 1;52(7):701-7
12372660
Emotion. 2007 May;7(2):336-53
17516812
Philos Trans R Soc Lond B Biol Sci. 2007 May 29;362(1481):933-42
17395573
Nature. 2005 Nov 24;438(7067):500-3
16306992
J Neurosci. 2007 Mar 21;27(12):3187-97
17376980
Neuroimage. 2009 Sep;47(3):852-63
19486944
J Neurosci. 2007 Aug 15;27(33):8877-84
17699669
J Exp Psychol Gen. 1999 Sep;128(3):309-331
10513398
Biol Psychol. 2008 Sep;79(1):30-42
18178303
Nat Neurosci. 2009 Jan;12(1):92-8
19079249
J Clin Exp Neuropsychol. 2002 Sep;24(6):781-91
12424652
Nat Neurosci. 2003 Mar;6(3):316-22
12592404
Nat Rev Neurosci. 2006 Oct;7(10):818-27
16988657
Neuroimage. 2010 Feb 1;49(3):2618-25
19770058
Trends Cogn Sci. 2005 May;9(5):242-9
15866151
Behav Genet. 2001 Nov;31(6):615-24
11838538
Psychon Bull Rev. 2002 Dec;9(4):637-71
12613671
Neuroimage. 2009 Nov 15;48(3):585-9
19615452
Proc Natl Acad Sci U S A. 2010 May 11;107(19):8871-6
20421489
Epidemiology. 2008 Sep;19(5):640-8
18633328
Neuropsychopharmacology. 2004 Nov;29(11):1943-61
15305167
Cogn Affect Behav Neurosci. 2005 Jun;5(2):182-90
16180624
Cogn Affect Behav Neurosci. 2005 Jun;5(2):144-55
16180621
Psychol Methods. 2005 Jun;10(2):178-92
15998176
Cogn Psychol. 2000 Aug;41(1):49-100
10945922
Neuroimage. 2008 Oct 1;42(4):1631-8
18634888
Perspect Psychol Sci. 2009 May;4(3):294-8
26158966
Front Hum Neurosci. 2009 Mar 30;3:4
19434242
J Cogn Neurosci. 2010 Jul;22(7):1614-22
19642882
Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22445-50
20080793
Mol Psychiatry. 2010 Sep;15(9):918-27
19417742
Cogn Affect Behav Neurosci. 2008 Mar;8(1):99-112
18405050
J Physiol. 2008 Dec 1;586(23):5717-25
18845611
J Pers Soc Psychol. 2009 Nov;97(5):883-92
19857008
Neuroscience. 2006 Apr 28;139(1):91-103
16324797
Philos Trans R Soc Lond B Biol Sci. 2007 Sep 29;362(1485):1601-13
17428778
Cereb Cortex. 2009 Feb;19(2):445-54
18550595
J Comp Neurol. 2005 Dec 5;493(1):99-110
16254995
Nat Neurosci. 2009 Aug;12(8):1062-8
19620978
Physiol Behav. 2007 Sep 10;92(1-2):186-92
17597168
Psychol Methods. 2002 Mar;7(1):19-40
11928888
Nat Neurosci. 2009 Jan;12(1):32-4
19029888
PLoS Comput Biol. 2009 May;5(5):e1000395
19492086
Nature. 2004 Apr 15;428(6984):748-51
15085132
Curr Opin Neurobiol. 2002 Apr;12(2):223-9
12015241
Nat Neurosci. 2009 Nov;12(11):1370-1
19820707
J Neurosci. 2006 Dec 20;26(51):13338-43
17182784
Proc Natl Acad Sci U S A. 2009 May 5;106(18):7351-6
19380750
Neuroscientist. 2008 Aug;14(4):381-95
18660464
Neuroimage. 2009 Jul 15;46(4):1148-53
19328237
Behav Genet. 2001 Nov;31(6):581-92
11838535
Science. 2009 Feb 6;323(5915):800-2
19197069
Nat Neurosci. 2004 Jan;7(1):75-9
14699419
Perspect Psychol Sci. 2009 May;4(3):274-90
26158964
J Neurosci. 2008 Jan 30;28(5):1208-12
18234898
Nat Neurosci. 2008 Jan;11(1):103-7
18066057
Arch Gen Psychiatry. 2003 Sep;60(9):889-96
12963670
Neuroimage. 2010 Jan 15;49(2):1868-74
19770056
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17558-63
19805061