Injectable and fast resorbable calcium phosphate cement for body-setting bone grafts.
In this work a calcium phosphate (CPC)/polymer blend was developed with the advantage of being moldable and capable of in situ setting to form calcium deficient hydroxyapatite under physiological conditions in an aqueous environment at body temperature. The CPC paste consists in a mix of R cement, glycerol as a liquid phase carrier and a biodegradable hydrogel such as Polyvinyl alcohol, which acts as a binder. Microstructure and mechanical analysis shows that the CPC blend can be used as an injectable implant for low loaded applications and fast adsorption requirements. The storage for commercial distribution was also evaluated and the properties of the materials obtained do not significantly change during storage at -18 degrees C.
Rajzer
I
I
Institute for Bioengineering of Catalonia (IBEC), C/Baldiri i Reixach, 4-6, Tower I, 10th floor, 08028 Barcelona, Spain.
Castaño
O
O
Engel
E
E
Planell
J A
JA
D001843:Bone Cements / Q000737:chemistry*; D016025:Bone Transplantation; D002130:Calcium Phosphates / Q000737:chemistry*; D004304:Dosage Forms; D017886:Durapatite / Q000737:chemistry; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D007267:Injections; D011108:Polymers / Q000737:chemistry
D001843:Bone Cements; D002130:Calcium Phosphates; D004304:Dosage Forms; D011108:Polymers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D017886:Durapatite; C020243:calcium phosphate
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