Cystic fibrosis and Crohn's disease: successful treatment and long term remission with infliximab.
The association of cystic fibrosis and Crohn's disease (CD) is well known, but to date, there are very few cases in the literature of patients suffering from mucoviscidosis who have required treatment with infliximab. We report the case of a 23-year-old patient suffering from cystic fibrosis and severe CD treated successfully with infliximab without any infective complications or worsening of the pulmonary disease and with a long term (2 years) complete remission.
Vincenzi
Francesca
F
Gastroenterology and Endoscopy Unit, University of Parma, via Gramsci 14, 43100 Parma, Italy.
Bizzarri
Barbara
B
Ghiselli
Alessia
A
de' Angelis
Nicola
N
Fornaroli
Fabiola
F
de' Angelis
Gian Luigi
GL
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D003113:Colonoscopy / Q000379:methods; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000188:drug therapy*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007249:Inflammation; D000069285:Infliximab; D008171:Lung Diseases / Q000188:drug therapy / Q000628:therapy; D012074:Remission Induction; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; C505032:CFTR protein, human; D007166:Immunosuppressive Agents; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D000069285:Infliximab
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