title: Physiologic 18F-FDG uptake in the fallopian tubes at mid cycle on PET/CT.
abstract: We observed bilateral pelvic foci of (18)F-FDG uptake (BiPF) exclusively in females--a finding not previously reported--and assessed the frequency, anatomic localization, and clinical significance of the uptake.
  
  
  METHODS
  On (18)F-FDG PET/CT and coregistered contrast-enhanced CT scans of 159 females (age, 16-81 y), the presence of BiPF and their location were evaluated. The findings were correlated with the age and menstrual history of the patient.
  
  
  RESULTS
  BiPF were seen in 14 (22%) of 63 patients up to 53 y old, predominantly at mid menstrual cycle, and were best coregistered to the fallopian tubes on contrast-enhanced CT. None of 96 patients older than 53 y showed BiPF.
  
  
  CONCLUSIONS
  Fallopian (18)F-FDG uptake was seen predominantly in premenopausal women at mid menstrual cycle. This finding is in accordance with known cyclic changes of fallopian tubes in response to ovarian hormones and may be the first, to our knowledge, imaging evidence revealing the influence of estrogen on the fallopian tubes.
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: Mijin
authors.initials: M
authors.lastname: Yun
authors.forename: Arthur
authors.initials: A
authors.lastname: Cho
authors.forename: Jae Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Yun-Jung
authors.initials: YJ
authors.lastname: Choi
authors.forename: Jong Doo
authors.initials: JD
authors.lastname: Lee
authors.forename: Chun K
authors.initials: CK
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D004967:Estrogens / Q000502:physiology; D005187:Fallopian Tubes / Q000000981:diagnostic imaging* / Q000378:metabolism*; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D005833:Genital Neoplasms, Female / Q000000981:diagnostic imaging; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008597:Menstrual Cycle / Q000502:physiology*; D008875:Middle Aged; D010052:Ovariectomy; D010388:Pelvis / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D012189:Retrospective Studies; D014055:Tomography, Emission-Computed; D055815:Young Adult
chemical_list: D004967:Estrogens; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18