title: Unusual cardiac associations with Tetralogy of Fallot-a descriptive study.
abstract: We present a large single-center series (>2200 cases) operated for Tetralogy of Fallot (TOF). We analyzed the incidence of associated unusual and uncommonly described cardiac lesions and their diagnostic and therapeutic implications in TOF patients. This retrospective study was conducted by reviewing records of patients operated for TOF at a large tertiary care pediatric cardiac centre. From 2002 to 2008, a total of 2235 cases of TOF were evaluated with echocardiography, cardiac catheterization, and/or cardiac computed tomography followed by cardiac surgery. Known and well-described associations were excluded from the study. Unusual associations were tabulated. Several unusual associations having an incidence >0.1% were detected. These included subaortic membrane (1%), pulmonary venous abnormalities (0.5%), small left ventricle (0.5%), interrupted inferior vena cava (0.5%), mitral valve abnormalities (0.4%), hemitruncus (0.4%), tricuspid valve abnormalities (0.4%), biventricular dysfunction (0.3%), retroaortic innominate vein (0.3%), bicuspid aortic valve (0.2%), and pericardial effusion (0.2%). This series describes unusual, not previously routinely reported cardiac lesions associated with TOF that may affect management and should be sought on preoperative evaluation. We demonstrate that more unusual associations do exist in not infrequent numbers, i.e., a TET is not just a TET.
authors.affiliation: Department of Pediatric Cardiology, Narayana Hrudayalaya Institute of Medical Sciences, Room no-7, 258/A-Bommasandra Industrial Area, Anekal Taluk, Hosur Road, Bangalore 560099, India. vishal5644@yahoo.co.in
authors.forename: Vishal
authors.initials: V
authors.lastname: Changela
authors.forename: Colin
authors.initials: C
authors.lastname: John
authors.forename: Sunita
authors.initials: S
authors.lastname: Maheshwari
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D006351:Heart Valves / Q000002:abnormalities*; D006352:Heart Ventricles / Q000002:abnormalities*; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011667:Pulmonary Veins / Q000002:abnormalities*; D012189:Retrospective Studies; D013771:Tetralogy of Fallot / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000002:abnormalities*; D055815:Young Adult
references.citation: Ann Thorac Surg. 2001 Jan;71(1):355-6
references.pmid: 11216782
references.citation: Ann Thorac Surg. 2002 Mar;73(3):967-9
references.pmid: 11899215
references.citation: Chest. 1976 Apr;69(4):543-4
references.pmid: 944120
references.citation: Br Heart J. 1990 Nov;64(5):325-8
references.pmid: 2245112
references.citation: J Ultrasound Med. 2007 Aug;26(8):1115-7
references.pmid: 17646377
references.citation: J Am Coll Cardiol. 2004 Mar 17;43(6):1068-74
references.pmid: 15028368
references.citation: Pediatr Cardiol. 1997 Sep-Oct;18(5):381-4
references.pmid: 9270111
references.citation: J Thorac Cardiovasc Surg. 2005 Jun;129(6):1448-50
references.pmid: 15942598
references.citation: Pediatr Cardiol. 1994 Mar-Apr;15(2):95-9
references.pmid: 7997423
references.citation: Jpn Heart J. 2002 Jul;43(4):429-32
references.pmid: 12227719
references.citation: Pediatr Cardiol. 1992 Jan;13(1):37-40
references.pmid: 1531256
references.citation: Asian Cardiovasc Thorac Ann. 2007 Aug;15(4):335-8
references.pmid: 17664210
references.citation: J Med Case Rep. 2008 Apr 28;2:127
references.pmid: 18442391
references.citation: Pediatr Cardiol. 1997 Jan-Feb;18(1):57-60
references.pmid: 8960496
references.citation: Cardiol Young. 2004 Aug;14(4):456-9
references.pmid: 15680057
references.citation: Indian Heart J. 2008 Mar-Apr;60(2):146-8
references.pmid: 19218725
references.citation: Pediatr Cardiol. 1987;8(2):131-4
references.pmid: 3628069
references.citation: Arch Mal Coeur Vaiss. 2006 Jan;99(1):77-9
references.pmid: 16479895
references.citation: Ann Thorac Surg. 1998 Oct;66(4):1403-5
references.pmid: 9800843
references.citation: Ann Pediatr Cardiol. 2008 Jul;1(2):139-41
references.pmid: 20300257
references.citation: Pediatr Cardiol. 1986;7(2):75-8
references.pmid: 3797289
references.citation: Tex Heart Inst J. 1997;24(3):215-7
references.pmid: 9339511
references.citation: Ann Thorac Surg. 2002 Jul;74(1):133-8
references.pmid: 12118745