[Mycosis fungoides and its new paradigm].
Primary cutaneous lymphomas are distinguished by singular clinical, histological and prognostic features that are not shared by other lymphomas originating from the lymphoid tissues. This review is an update of the current concepts about the biology, diagnosis and treatment of mycosis fungoides, the most frequent entity among the primary cutaneous T cell lymphomas. It is currently established that mycosis fungoides originates from T lymphocytes normally homing the dermis. Such a situation implies that treatments at least in the initial stages of the disease, should primarily target the skin without searching for an impact on internal lymphoid tissues.
Quatresooz
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P
Service de Derma-topathologie, CHU de Liège, Belgique.
Piérard
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GE
D000279:Administration, Cutaneous; D001530:Belgium / Q000453:epidemiology; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D009182:Mycosis Fungoides / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D009367:Neoplasm Staging; D010789:Phototherapy; D015995:Prevalence; D011379:Prognosis; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D015996:Survival Rate; D013601:T-Lymphocytes / Q000473:pathology
D005938:Glucocorticoids