Plasma cortisol concentrations after CIDR insertion in beef cows.
The objective of this study was to show plasma cortisol concentration after treatment with controlled internal drug release (CIDR) in non-suckling beef cows. On day 9 after oestrus, two cows were inserted with CIDR into the vagina for 24 h and the other two cows were treated as a control group. Four days later, the two control cows were treated with CIDR and the other two CIDR-treated cows were used as controls. Cortisol concentrations were determined by ELISA in plasma samples collected before, during and after insertion of CIDR. There was a significant increase in plasma cortisol concentrations (p<0.01) after insertion of CIDR. Mean (± SEM) plasma cortisol concentrations increased from 1.3 ± 0.4 to a peak of 8.8 ± 1.1 ng/ml at 5 h and then decreased to basal concentrations at 7 h after insertion of the device. In conclusion, the insertion of intra-vaginal device causes an increase in plasma cortisol concentrations in beef cows, although the pathophysiological significance of the elevation of cortisol is not known.
Long
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Laboratory of Theriogenology, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, Yamaguchi, Japan.
Thinh
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Yusuf
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Nakao
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D000282:Administration, Intravaginal; D000818:Animals; D002417:Cattle; D005260:Female; D006854:Hydrocortisone / Q000097:blood*; D015918:Infusion Pumps, Implantable / Q000009:adverse effects / Q000662:veterinary*; D010146:Pain / Q000662:veterinary; D011374:Progesterone / Q000008:administration & dosage / Q000097:blood; D013312:Stress, Physiological
D011374:Progesterone; D006854:Hydrocortisone