title: No advantage is gained by preoperative bowel preparation in radical cystectomy and ileal conduit: a randomized controlled trial of 86 patients.
abstract: OBJECTIVE
  Bowel preparation (BP) is performed routinely before intestinal surgery to reduce the risk of postoperative infectious complications. We studied the effect of BP on patients who underwent radical cystectomy and ileal conduit surgery. Our goal was to determine whether BP in these patients provided any benefits postoperatively.
  
  
  METHODS
  Between Match 2006 and January 2009, 86 patients scheduled for radical cystectomy and ileal conduit were randomized to preoperative BP (group A) or surgery without BP (group B). Outcomes studied included operative time, recovery of patient and surgical complications.
  
  
  RESULTS
  Eighty-six patients were included in the study, 47 in group A and 39 in group B. All surgeries were performed successfully using ileum. Postoperative complications were documented in 5 and 6 patients in groups A and B, respectively. Anastomotic leak occurred in 1 patient in group A, leading to multiple organ dysfunction and sepsis, with a fatal outcome. One case of ileus and three wound infections were also seen in group A. In group B, wound infection and ileus occurred in two patients each, anastomotic leak developed in 1 patient resulting to reoperation and one patient died from pulmonary embolism. No statistical difference in the frequency of complications and recovery of patient was observed between the 2 groups.
  
  
  CONCLUSIONS
  Our results suggest that no advantage is gained by preoperative BP in radical cystectomy and ileal conduit.
authors.affiliation: Department of Urology, The Second Xiangya Hospital, Central South University, 410011 Changsha, Hunan, People’s Republic of China.
authors.forename: Ran
authors.initials: R
authors.lastname: Xu
authors.forename: Xiaokun
authors.initials: X
authors.lastname: Zhao
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Zhong
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002400:Cathartics; D015653:Cystectomy; D005260:Female; D006801:Humans; D007082:Ileum / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011446:Prospective Studies
chemical_list: D002400:Cathartics
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