title: Allergy-preventive effects of the flowers of Impatiens textori.
abstract: The allergy-preventive activity of a 35% EtOH extract (IT) of flowers of Impatiens textori MIQ. was demonstrated in a continuing search for allergy-preventive substances from natural sources. The evaluation of its activity used an in vivo assay method for monitoring the blood flow decrease in the tail vein microcirculation of mice subjected to sensitization with hen-egg white lysozyme. Among the principal compounds in IT, apigenin (1), luteolin (3), and luteolin 7-glucoside (4) showed significant allergy-preventive effects.
authors.affiliation: Department of Pharmacy, Hyogo University of Health Sciences, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Iwaoka
authors.forename: Hisae
authors.initials: H
authors.lastname: Oku
authors.forename: Munekazu
authors.initials: M
authors.lastname: Iinuma
authors.forename: Kyoko
authors.initials: K
authors.lastname: Ishiguro
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D047310:Apigenin / Q000494:pharmacology; D002645:Chickens; D004529:Egg White; D047309:Flavones / Q000494:pharmacology; D035264:Flowers; D005960:Glucosides / Q000494:pharmacology*; D018056:Hemorheology / Q000187:drug effects; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*; D029069:Impatiens / Q000737:chemistry*; D047311:Luteolin / Q000494:pharmacology; D051379:Mice; D009113:Muramidase; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D013623:Tail / Q000098:blood supply
chemical_list: D018926:Anti-Allergic Agents; D047309:Flavones; D005960:Glucosides; D010936:Plant Extracts; D047310:Apigenin; D009113:Muramidase; D047311:Luteolin