Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia.
Virely
C
C
Moulin
S
S
Cobaleda
C
C
Lasgi
C
C
Alberdi
A
A
Soulier
J
J
Sigaux
F
F
Chan
S
S
Kastner
P
P
Ghysdael
J
J
D000818:Animals; D005260:Female; D005434:Flow Cytometry; D016044:Fusion Proteins, bcr-abl / Q000502:physiology*; D016147:Genes, Tumor Suppressor / Q000502:physiology*; D006801:Humans; D051740:Ikaros Transcription Factor / Q000502:physiology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology* / Q000473:pathology*; D015996:Survival Rate
D051740:Ikaros Transcription Factor; D016044:Fusion Proteins, bcr-abl