Efficient alkene synthesis on solid support using the Julia-Kocienski coupling.
An efficient application of the Julia-Kocienski coupling for the olefination of aldehydes with resin-bound benzothiazol-2-yl and 1-phenyl-1H-tetrazol-5-yl sulfones is described. Olefins is generally obtained in high overall yield for the six-reaction steps.
Boggián
Dora B
DB
Instituto de Química Rosario (CONICET - UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000, Rosario, Argentina.
Mata
Ernesto G
EG
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000295:instrumentation / Q000379:methods*; D003500:Cyclization; D004526:Efficiency; D008954:Models, Biological; D013450:Sulfones / Q000737:chemistry
D000475:Alkenes; D013450:Sulfones
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