title: Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage.
abstract: This article describes a synthetic route to generate two purine-pyrimidine and pyrimidine heterodinucleosides. Both microwave activated regioselective alkylation using hydride and copper-catalyzed-azide-alkyne-cycloaddition (CuAAC) were used in order to perform the synthesis.
authors.affiliation: Faculte des Sciences et Techniques, Universite de Limoges, Laboratoire de Chimie des Substances Naturelles, Limoges, France.
authors.forename: R
authors.initials: R
authors.lastname: Lucas
authors.forename: P H
authors.initials: PH
authors.lastname: Elchinger
authors.forename: P A
authors.initials: PA
authors.lastname: Faugeras
authors.forename: R
authors.initials: R
authors.lastname: Zerrouki
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D011687:Purines; D011743:Pyrimidines; D014230:Triazoles; D003300:Copper; C030986:pyrimidine; C030985:purine