title: [Lecithin influence on the effectiveness of the antioxidant effect of flavonoids and alpha-tocopherol].
abstract: Influence of the widely used food supplement lecithin on the effectiveness of the inhibiting effect of the natural antioxidants (quercitin, dihydroquercitin, and alpha-tocopherol) has been studied in dependence of the rate of free radicals generation in the model oxidation reactions. It has been found that during the initiated and autoxidation of methyl oleat, lecithin decreased the antioxidant effectiveness of flavonoids. The effect value increased with the lecithin concentration increase. In similar conditions while oxidation inhibiting by alpha-tocopherol and lecithin mixtures, the latter did not influence the tocopherol antioxidant effectiveness (additivity) or led to the increase of the inhibition effectiveness (synergism).
authors.forename: L I
authors.initials: LI
authors.lastname: Mazaletskaia
authors.forename: N I
authors.initials: NI
authors.lastname: Sheludchenko
authors.forename: L N
authors.initials: LN
authors.lastname: Shishkina
mesh_terms: D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology*; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000378:metabolism / Q000494:pharmacology*; D054709:Lecithins / Q000494:pharmacology*; D009829:Oleic Acids / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D011794:Quercetin / Q000378:metabolism / Q000494:pharmacology; D013501:Surface-Active Agents / Q000494:pharmacology*; D013997:Time Factors; D024502:alpha-Tocopherol / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D054709:Lecithins; D009829:Oleic Acids; D013501:Surface-Active Agents; C005576:methyl oleate; D011794:Quercetin; D024502:alpha-Tocopherol