Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism.
The marine environment is extremely diverse, with huge variations in pressure and temperature. Nevertheless, life, especially microbial life, thrives throughout the marine biosphere and microbes have adapted to all the divergent environments present. Large scale DNA sequence based approaches have recently been used to investigate the marine environment and these studies have revealed that the oceans harbor unprecedented microbial diversity. Novel gene families with representatives only within such metagenomic datasets represent a large proportion of the ocean metagenome. The presence of so many new gene families from these uncultured and highly diverse microbial populations represents a challenge for the understanding of and exploitation of the biology and biochemistry of the ocean environment. The application of new metagenomic and single cell genomics tools offers new ways to explore the complete metabolic diversity of the marine biome.
Kennedy
Jonathan
J
Marine Biotechnology Centre, Environmental Research Institute, University College Cork, Cork, Ireland. jonathan.kennedy@ucc.ie
Flemer
Burkhardt
B
Jackson
Stephen A
SA
Lejon
David P H
DP
Morrissey
John P
JP
O'Gara
Fergal
F
Dobson
Alan D W
AD
D001419:Bacteria / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism*; D001709:Biotechnology; D057225:Data Mining; D008386:Marine Biology; D056186:Metagenomics / Q000379:methods; D012623:Seawater / Q000382:microbiology*; D014871:Water Microbiology
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