The role of spectral-domain optical coherence tomography in the diagnosis of retinal angiomatous proliferation.
BACKGROUND
We present the findings of spectral-domain optical coherence tomography (OCT) in 8 patients with retinal angiomatous proliferation.


METHODS
Eight patients with a known history of age-related macular degeneration presented with a recent decrease of visual acuity in one eye. On fundus examination, all patients showed an elevated macular lesion associated with intra- or subretinal hemorrhage and retinal hard exudates. Fluorescein and indocyanine-green (ICG) angiography, together with spectral-domain OCT (Optopol Copernicus SOCT), were performed.


RESULTS
Fluorescein angiography showed early hyperfluorescence with late leakage in all cases. A serous pigment epithelium detachment was present in 6 cases. ICG angiography showed a hot spot in the macular area. The OCT showed a serous pigment epithelium detachment in 6 cases and intraretinal cysts in all cases. The line crossing the ICG visible hot spot showed a greatly hyperreflective intraretinal lesion located at various depths inside the retina.


CONCLUSIONS
Spectral-domain OCT is a useful complementary tool to confirm the diagnosis of retinal angiomatous proliferation. Its high resolution and speed enables accurate localization of the angiomatous lesion.
Petropoulos
I K
IK
Ophthalmological Center of Terrassière, Geneva, Switzerland. ipetropoulos@cot-ge.ch
Matter
M A
MA
Katsimpris
J M
JM
Desmangles
P M
PM
D000368:Aged; D000369:Aged, 80 and over; D000798:Angiomatosis / Q000150:complications* / Q000473:pathology*; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D015861:Retinal Neovascularization / Q000150:complications* / Q000473:pathology*; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*