Morphological changes in paraurethral area after introduction of tissue engineering construct on the basis of adipose tissue stromal cells.
We studied morphological changes in the paraurethral area of Wistar rats after introduction of tissue engineering constructs on the basis of multipotent mesenchymal stem cells and gelatin sponge. The tissue engineering construct containing autologous culture of the stromal fraction of the adipose tissue was most effective. After introduction of this construct we observed more rapid degradation of the construct matrix and more intensive formation of collagen fibers.
Makarov
A V
AV
ReMeTeks Company, Moscow, Russia. anvitmak@yandex.ru
Arutyunyan
I V
IV
Bol'shakova
G B
GB
Volkov
A V
AV
Gol'dshtein
D V
DV
D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D018929:Cell Culture Techniques; D002478:Cells, Cultured; D005109:Extracellular Matrix / Q000378:metabolism; D005260:Female; D020007:Implants, Experimental; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D039902:Multipotent Stem Cells / Q000166:cytology / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D017154:Stromal Cells / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds; D014521:Urethra / Q000033:anatomy & histology*