Kinetics of liver volume changes in the first year after portal vein embolization.
OBJECTIVE
To determine the time course of liver hypertrophy after portal vein embolization (PVE).


METHODS
In a cohort study, computed tomography volumetrics were calculated for livers during a 1-year period after PVE.


METHODS
Tertiary liver cancer treatment center.


METHODS
Ten patients who were subjected to PVE and were found subsequently to not be candidates for liver resection.


METHODS
Right PVE.


METHODS
Left and right liver volumes.


RESULTS
The left liver continued growing for the entire first year after PVE, while the right liver continued to atrophy. The total volume remained remarkably constant.


CONCLUSIONS
Early PVE during administration of a course of neoadjuvant therapy would be beneficial for enhanced growth of the liver before liver resection.
Corrêa
Danton
D
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Schwartz
Lawrence
L
Jarnagin
William R
WR
Tuorto
Scott
S
DeMatteo
Ronald
R
D'Angelica
Michael
M
Allen
Peter
P
Brown
Karen
K
Fong
Yuman
Y
D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D000368:Aged; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed