title: Current approaches to diagnosing and managing constipation in advanced cancer and palliative care.
abstract: Constipation is common in advanced cancer. Despite this, clinicians' understanding of the underlying changes affecting the colon and the rest of the gastrointestinal tract are limited. Two case histories are used to illustrate the problems encountered when the current approaches to diagnosing and managing altered bowel habits are unsuccessful. An alternative paradigm in which to consider the problems of constipation encountered by some people with advanced cancer is proposed.
authors.affiliation: Royal Hospital for Women, Darlinghurst, New South Wales, Australia. kclark3@nd.edu.au
authors.forename: Katherine
authors.initials: K
authors.lastname: Clark
authors.forename: Kat
authors.initials: K
authors.lastname: Urban
authors.forename: David C
authors.initials: DC
authors.lastname: Currow
mesh_terms: D002400:Cathartics / Q000627:therapeutic use; D003248:Constipation / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000628:therapy; D004573:Electrolytes / Q000627:therapeutic use; D004733:Enema; D005260:Female; D006801:Humans; D007792:Lactulose / Q000627:therapeutic use; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010166:Palliative Care; D010710:Phosphates / Q000627:therapeutic use; D011092:Polyethylene Glycols / Q000627:therapeutic use
chemical_list: D002400:Cathartics; D004573:Electrolytes; D010710:Phosphates; D011092:Polyethylene Glycols; D007792:Lactulose; C018279:sodium phosphate