Treatment of acute colonic pseudo-obstruction with tegaserod.
Acute colonic pseudo-obstruction is characterized by symptoms, signs and radiologic appearance of large bowel obstruction in the absence of a true mechanical obstruction. Several pharmacologic treatments have been proposed. We present a case of a patient with Guillain-Barré syndrome complicated by acute colonic pseudo-obstruction, who had a clinical response to tegaserod, a partial 5-hydroxytryptamine type-4 agonist. 5-Hydroxytryptamine type 4 agonists may be an option in the treatment of acute colonic pseudo-obstruction.
Ramirez
Ruben
R
Texas Tech University Health Sciences Center, El Paso, USA.
Zuckerman
Marc J
MJ
Hejazi
Reza A
RA
Chokhavatia
Sita
S
D000208:Acute Disease; D003112:Colonic Pseudo-Obstruction / Q000150:complications / Q000188:drug therapy*; D054333:Drug Partial Agonism; D020275:Guillain-Barre Syndrome / Q000150:complications; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D058828:Serotonin 5-HT4 Receptor Agonists
D007211:Indoles; D058828:Serotonin 5-HT4 Receptor Agonists; C105050:tegaserod