title: Synthesis and antipsychotic and anticonvulsant activity of some new substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles.
abstract: A novel substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles (4a-j), (5a-j) and (6a-j) were synthesized and screened for their antipsychotic and anticonvulsant activities. It is concluded from the results compound 6j showed promising antipsychotic as well as anticonvulsant activity.
authors.affiliation: Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Garh Road, Meerut 250004, Uttar Pradesh, India.
authors.forename: Hemlata
authors.initials: H
authors.lastname: Kaur
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
authors.forename: Pinki
authors.initials: P
authors.lastname: Vishwakarma
authors.forename: Monica
authors.initials: M
authors.lastname: Sharma
authors.forename: K K
authors.initials: KK
authors.lastname: Saxena
authors.forename: Ashok
authors.initials: A
authors.lastname: Kumar
mesh_terms: D000927:Anticonvulsants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D014150:Antipsychotic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D012640:Seizures / Q000517:prevention & control; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity
chemical_list: D000927:Anticonvulsants; D014150:Antipsychotic Agents; D002227:Carbazoles; D010069:Oxadiazoles; D013830:Thiadiazoles