Facile synthesis of polysubstituted oxazoles via a copper-catalyzed tandem oxidative cyclization.
A highly efficient synthesis of polysubstituted oxazoles was developed via a copper-catalyzed tandem oxidative cyclization. The desired products can be obtained from readily available starting materials under mild conditions. This is an attractive alternative method for the synthesis of oxazole derivatives.
Wan
Changfeng
C
Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, PR China.
Zhang
Jintang
J
Wang
Sujing
S
Fan
Jinmin
J
Wang
Zhiyong
Z
D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D009942:Organometallic Compounds; D010080:Oxazoles; D003300:Copper