Synthesis of alkyl alkynyl ketones by Pd/light-induced three-component coupling reactions of iodoalkanes, CO, and 1-alkynes.
Under photoirradiation conditions using xenon light, in the presence of a catalytic amount of PdCl(2)(PPh(3))(2) with triethylamine as a base, a three-component coupling reaction of iodoalkanes, carbon monoxide, and terminal alkynes proceeded to give alkyl alkynyl ketones in good yields.
Fusano
Akira
A
Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
Fukuyama
Takahide
T
Nishitani
Satoshi
S
Inouye
Takaya
T
Ryu
Ilhyong
I
D000480:Alkynes / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D008027:Light; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D006847:Hydrocarbons, Iodinated; D007659:Ketones; D010165:Palladium; D002248:Carbon Monoxide