Photoprotective compounds from marine organisms.
The substantial loss in the stratospheric ozone layer and consequent increase in solar ultraviolet radiation on the earth's surface have augmented the interest in searching for natural photoprotective compounds in organisms of marine as well as freshwater ecosystems. A number of photoprotective compounds such as mycosporine-like amino acids (MAAs), scytonemin, carotenoids and several other UV-absorbing substances of unknown chemical structure have been identified from different organisms. MAAs form the most common class of UV-absorbing compounds known to occur widely in various marine organisms; however, several compounds having UV-screening properties still need to be identified. The synthesis of scytonemin, a predominant UV-A-photoprotective pigment, is exclusively reported in cyanobacteria. Carotenoids are important components of the photosynthetic apparatus that serve both light-harvesting and photoprotective functions, either by direct quenching of the singlet oxygen or other toxic reactive oxygen species or by dissipating the excess energy in the photosynthetic apparatus. The production of photoprotective compounds is affected by several environmental factors such as different wavelengths of UVR, desiccation, nutrients, salt concentration, light as well as dark period, and still there is controversy about the biosynthesis of various photoprotective compounds. Recent studies have focused on marine organisms as a source of natural bioactive molecules having a photoprotective role, their biosynthesis and commercial application. However, there is a need for extensive work to explore the photoprotective role of various UV-absorbing compounds from marine habitats so that a range of biotechnological and pharmaceutical applications can be found.
Rastogi
Rajesh P
RP
Laboratory of Photobiology and Molecular Microbiology, Centre of Advanced Study in Botany, Banaras Hindu University, Varanasi 221005, India.
Richa
Sinha
Rajeshwar P
RP
Singh
Shailendra P
SP
Häder
Donat-P
DP
D000596:Amino Acids / Q000096:biosynthesis; D000818:Animals; D002338:Carotenoids / Q000378:metabolism; D000458:Cyanobacteria / Q000378:metabolism; D017753:Ecosystem; D056890:Eukaryota / Q000378:metabolism; D005658:Fungi / Q000378:metabolism; D006801:Humans; D007211:Indoles / Q000302:isolation & purification / Q000378:metabolism; D010636:Phenols / Q000302:isolation & purification / Q000378:metabolism; D020011:Protective Agents / Q000302:isolation & purification* / Q000378:metabolism / Q000627:therapeutic use; D012623:Seawater / Q000382:microbiology; D014466:Ultraviolet Rays
D000596:Amino Acids; D007211:Indoles; D010636:Phenols; D020011:Protective Agents; C083368:scytonemin; D002338:Carotenoids
Biochemistry. 1970 Dec 8;9(25):4914-21
5480156
Biochem J. 1981 Dec 1;199(3):741-7
7200360
Chem Rev. 2004 Apr;104(4):2021-71
15080720
Annu Rev Physiol. 2002;64:223-62
11826269
Photochem Photobiol. 2008 Nov-Dec;84(6):1500-5
18557824
Nat Prod Rep. 2007 Feb;24(1):31-86
17268607
Photochem Photobiol. 2007 Sep-Oct;83(5):1074-94
17880503
Inflamm Res. 2002 Feb;51(2):112-4
11926312
Mol Biotechnol. 2007 Sep;37(1):26-30
17914160
Photochem Photobiol Sci. 2009 Sep;8(9):1276-94
19707616
Environ Microbiol. 2005 Apr;7(4):593-601
15816936
J Photochem Photobiol B. 2001 Jul;60(2-3):129-35
11470569
FEMS Microbiol Lett. 2007 Apr;269(1):1-10
17286572
Mol Biol Evol. 2008 Dec;25(12):2653-67
18799712
Mar Drugs. 2008 May 22;6(2):147-63
18728764
J Am Chem Soc. 2008 Nov 19;130(46):15260-1
18954141
Science. 1992 Feb 21;255(5047):952-9
1546292
Br J Nutr. 2004 Jan;91(1):53-61
14748938
J Photochem Photobiol B. 2009 Mar 3;94(3):191-200
19128981
J Bacteriol. 1997 Mar;179(6):1940-5
9068639
J Invest Dermatol. 2005 Feb;124(2):428-34
15675964
Photochem Photobiol. 1992 Jul;56(1):17-23
1508978
Trends Biotechnol. 2003 May;21(5):210-6
12727382
J Exp Mar Biol Ecol. 2000 Nov 20;254(2):221-234
11077062
Clin Dermatol. 1998 Jan-Feb;16(1):83-9
9472437
Acta Biochim Pol. 2006;53(3):429-43
16951740
Experientia. 1993 Sep 15;49(9):825-9
8405307
Planta. 2008 Dec;229(1):225-33
18830707
Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):136-43
16487047
Biol Rev Camb Philos Soc. 1999 Aug;74(3):311-45
10466253
J Photochem Photobiol B. 2002 Feb;66(1):60-6
11849984
Mar Drugs. 2009 Jul 21;7(3):341-54
19841718
Biomol Eng. 2003 Jul;20(4-6):183-9
12919796
FASEB J. 1996 May;10(7):690-701
8635686
J Nat Prod. 2004 Apr;67(4):678-81
15104503
Eukaryot Cell. 2007 Mar;6(3):533-45
17085635
Free Radic Res Commun. 1991;12-13 Pt 2:845-50
1905671
J Photochem Photobiol B. 2005 Aug 1;80(2):115-21
15893470
FEMS Microbiol Ecol. 2008 Mar;63(3):301-8
18218026
Genomics. 2010 Feb;95(2):120-8
19879348
Mar Drugs. 2009 Jul 13;7(3):314-30
19841716
Gene. 1991 Dec 20;109(1):131-6
1756973
J Photochem Photobiol B. 1991 May;9(2):135-60
1907647
J Bacteriol. 2007 Jun;189(12):4465-72
17351042
Pigment Cell Res. 2002 Apr;15(2):104-11
11936267
Annu Rev Nutr. 1986;6:273-97
3524619
Mar Biotechnol (NY). 2003 Mar-Apr;5(2):194-200
12876656
Biochim Biophys Acta. 2001 May 5;1547(1):104-16
11343796
J Pharmacol Exp Ther. 2002 Nov;303(2):858-66
12388673
J Photochem Photobiol B. 2001 Sep 1;62(1-2):26-34
11693364
Biochim Biophys Acta. 1995 May 11;1244(1):165-8
7766653
J Phycol. 2009 Feb;45(1):16-33
27033642
Mar Biotechnol (NY). 2009 Jan-Feb;11(1):74-80
18607659
Photochem Photobiol Sci. 2006 Apr;5(4):432-5
16583025
Photochem Photobiol. 2000 Apr;71(4):493-8
10824604
J Chem Ecol. 2005 Oct;31(10):2417-38
16195852
Appl Environ Microbiol. 2007 Apr;73(7):2173-9
17277219
J Photochem Photobiol B. 2002 Feb;66(1):47-53
11849982
J Photochem Photobiol B. 2003 Oct 15;71(1-3):51-8
14705639
PLoS One. 2008 Aug 06;3(8):e2896
18682837
J Photochem Photobiol B. 2004 Sep 8;75(3):145-55
15341928
Mar Biotechnol (NY). 2008 Mar-Apr;10(2):141-50
18157682
Nat Prod Rep. 2007 Aug;24(4):774-97
17653359
J Photochem Photobiol B. 2009 Feb 9;94(2):82-6
19036601
Protist. 2001 Jul;152(2):93-101
11545441
Appl Environ Microbiol. 2009 Jul;75(14):4861-9
19482954
Photochem Photobiol Sci. 2002 Sep;1(9):678-85
12665305
Plant Physiol. 1999 Jun;120(2):599-604
10364412
J Cosmet Sci. 2002 Jan-Feb;53(1):1-9
11917251
Photochem Photobiol Sci. 2002 Apr;1(4):225-36
12661961
J Gen Microbiol. 1993 May;139(5):1105-14
8336107
Int J Cosmet Sci. 1998 Feb;20(1):41-51
18505488
J Photochem Photobiol B. 2006 Sep 1;84(3):204-12
16697653
Annu Rev Nutr. 2004;24:173-200
15189118
Biomed Pharmacother. 2004 Mar;58(2):100-10
14992791
J Photochem Photobiol B. 1997 Dec;41(3):189-200
9447718
Arch Microbiol. 1998 Jun;169(6):469-82
9575232
Ageing Res Rev. 2010 Apr;9(2):79-90
19524071
J Phys Chem B. 2006 Mar 30;110(12):6359-64
16553454
Photochem Photobiol Sci. 2007 Jun;6(6):669-74
17549269
Int J Vitam Nutr Res. 2005 Jan;75(1):54-60
15830922
J Sep Sci. 2005 Sep;28(14):1685-93
16224962
J Exp Mar Biol Ecol. 2000 Dec 1;255(1):93-110
11090854
Photochem Photobiol. 2004 Jun;79(6):515-9
15291302
Biol Bull. 2002 Dec;203(3):315-30
12480722
Curr Opin Chem Biol. 2009 Apr;13(2):216-23
19307147
Mar Environ Res. 2009 Feb;67(1):8-16
19036429
J Photochem Photobiol B. 2005 Aug 1;80(2):71-8
16038805
Photochem Photobiol Sci. 2002 Oct;1(10):820-5
12656485
Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2533-7
18268342
Eukaryot Cell. 2006 Sep;5(9):1517-31
16963634
Arch Microbiol. 2002 Apr;177(4):322-31
11889486
J Photochem Photobiol B. 2000 Jul;56(2-3):139-44
11079474
Indian J Exp Biol. 2008 Jan;46(1):7-17
18697565
Photochem Photobiol. 2003 Aug;78(2):109-13
12945577
Nat Prod Rep. 1998 Apr;15(2):159-72
9586224
Photochem Photobiol Sci. 2007 Mar;6(3):267-85
17344962
Nat Chem Biol. 2006 Dec;2(12):666-73
17108984
Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):60-78
16901759
Biotechnol Adv. 2009 Jul-Aug;27(4):521-39
19393308
J Am Chem Soc. 1970 Aug 26;92(17):5216-8
5432666
Protist. 2006 Jun;157(2):185-91
16621697
Nutr Rev. 1993 Jul;51(7):199-204
8414223
Immunol Lett. 1999 Dec 1;70(3):185-9
10656672
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Dec;260(4):428-35
3834717
BMC Genomics. 2009 Jul 24;10:336
19630972
Biochim Biophys Acta. 2008 Oct;1777(10):1344-54
18694721
Environ Microbiol. 2007 Jun;9(6):1448-55
17504482
J Bacteriol. 2009 Jul;191(14):4639-46
19429608
J Photochem Photobiol B. 2007 Nov 12;89(1):29-35
17826148
Photochem Photobiol Sci. 2009 Sep;8(9):1266-75
19707615