(Eta6-arene) ruthenium(II) complexes and metallo-papain hybrid as Lewis acid catalysts of Diels-Alder reaction in water.
Covalent embedding of a (eta(6)-arene) ruthenium(II) complex into the protein papain gives rise to a metalloenzyme displaying a catalytic efficiency for a Lewis acid-mediated catalysed Diels-Alder reaction enhanced by two orders of magnitude in water.
Talbi
Barisa
B
Chimie ParisTech (Ecole Nationale Supérieure de Chimie de Paris), Laboratoire Charles Friedel, CNRS UMR 7223, 11 rue Pierre et Marie Curie, 75231, Paris cedex 05, France.
Haquette
Pierre
P
Martel
Annie
A
de Montigny
Frédéric
F
Fosse
Céline
C
Cordier
Stéphane
S
Roisnel
Thierry
T
Jaouen
Gérard
G
Salmain
Michèle
M
D000143:Acids / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007700:Kinetics; D008968:Molecular Conformation; D010206:Papain / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D000143:Acids; D056831:Coordination Complexes; D014867:Water; D012428:Ruthenium; D010206:Papain