Transition metal-catalyzed addition reactions of arylboronic acids with alkyl 2-formylbenzoates: efficient access to chiral 3-substituted phthalides.
Transition metal-catalyzed addition of arylboronic acids to 2-formylbenzoates afforded 3-substituted phthalides. By using SPINOL-based phosphites as ligands, a Rh(I)-catalyzed asymmetric version of such an addition reaction was achieved.
Xing
Chun-Hui
CH
Department of Chemistry, College of Staten Island and the Graduate Center of the City University of New York, 2800 Victory Boulevard, Staten Island, New York 10314, USA.
Liao
Yuan-Xi
YX
He
Ping
P
Hu
Qiao-Sheng
QS
D001565:Benzoates / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D009942:Organometallic Compounds / Q000737:chemistry; D013237:Stereoisomerism; D028561:Transition Elements / Q000737:chemistry*
D001565:Benzoates; D001572:Benzofurans; D001897:Boronic Acids; D009942:Organometallic Compounds; D028561:Transition Elements; C415768:tris(2,2'-bipyridyl)ruthenium(II); C082022:phthalide