title: [A case of a pulmonary pleomorphic carcinoma with fever which responded well to chemotherapy].
abstract: BACKGROUND
  Pulmonary pleomorphic carcinoma is a very rare pulmonary malignant tumor which has various clinical manifestations and a poor prognosis.
  
  
  METHODS
  A 74-year-old man presented with fever and weight loss of more than 10kg during 2 months from April 200X. Chest CT showed a nodule in the right upper lobe, and supraclavicular and mediastinal lymphadenopathy. Positron emission tomography (PET) comfirmed 18Ffluorodeoxyglucose accumulation in the sites. A left supraclavicular node biopsy demonstrated pulmonary pleomorphic carcinoma. The tumors responded well to gemcitabine plus docetaxel combination chemotherapy. This symptoms disappeared and the response continued for 1 year after 6 cycles of chemotherapy.
  
  
  CONCLUSIONS
  We report a case of pulmonary pleomorphic carcinoma presenting with fever, which showed a marked response to chemotherapy.
authors.affiliation: First Department of Internal Medicine, Shinshu University School of Medicine.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ichiyama
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Tanabe
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Agatsuma
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Koizumi
authors.forename: Keishi
authors.initials: K
authors.lastname: Kubo
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077143:Docetaxel; D005334:Fever / Q000150:complications; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D043823:Taxoids / Q000008:administration & dosage; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D043823:Taxoids; D003841:Deoxycytidine; D000077143:Docetaxel; D000093542:Gemcitabine