title: [Ultrasonographic diagnosis of venous thromboses].
abstract: The article deals with a new method of diagnosis of venous thromboses, which is based on ultrasonographic scanning of the area of the valvular sinuses of the femoral vein. The authors examined a total of two hundred and forty-nine people; of these, 100 patients were diagnosed as having varicose disease, 99 subjects had acute venous thrombosis, and 50 people constituted the control group. All the patients were examined by means of ultrasonographic angioscanning, and also had the D-dimer level measured in them. The carried out study resulted in a description of an ultrasonographic phenomenon consisting in the presence of echo-positive inclusions within the area of the valvular sinuses, which was called the sludge phenomenon. The authors developed a classification of this phenomenon, describing three degrees of sludge. Degree 1 sludge is a physiological one and reflects the fact that the area of the valvular sinuses is the most thrombogenic zone. Degree 2 sludge is characterized as a pathological one, being indicative of the presence of a prethrombotic condition and may serve as one of the earliest prognostic factors for the development of venous thrombosis. Degree 3 sludge reflects thrombosis of the valvular sinus. The carried out studies made it possible to reveal a correlation between the presence of a sludge, its degree, the presence of a venous thrombosis, and the values of the D-dimer level.
authors.forename: I M
authors.initials: IM
authors.lastname: Ignat'ev
authors.forename: R A
authors.initials: RA
authors.lastname: Bredikhin
authors.forename: E E
authors.initials: EE
authors.lastname: Fomina
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D003937:Diagnosis, Differential; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods*; D020246:Venous Thrombosis / Q000097:blood / Q000145:classification / Q000000981:diagnostic imaging*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D