Primary pulmonary coccidioidomycosis in China.
Coccidioidomycosis is a fungal infection endemic to south-west USA, north Mexico and parts of Central and South America. We report here a case of primary pulmonary coccidioidomycosis in a previously healthy 14-year-old boy in China, which is considered a non-endemic country. The patient had non-specific symptoms of pulmonary infection, including fever, non-productive cough and night sweats. Both spherules and endospores of Coccidioides immitis were seen histologically following transbronchial biopsy of a cavitary lesion. The patient was treated with amphotericin B and fluconazole. Follow up 6 months post discharge found that the patient made a good recovery.
Lan
Fen
F
Department of Respiratory Medicine, Tongji Hospital, Key Laboratory of Pulmonary Diseases of Ministry of Health of China, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tong
Yao-Zhi
YZ
Huang
Hong
H
Xiong
Wei-Ning
WN
Xu
Yong-Jian
YJ
Xiong
Sheng-Dao
SD
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use*; D044466:Asian People; D003045:Coccidioides / Q000302:isolation & purification; D003047:Coccidioidomycosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D003371:Cough / Q000188:drug therapy / Q000473:pathology; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D016896:Treatment Outcome
D000666:Amphotericin B; D015725:Fluconazole