title: Diabetes and weight management.
abstract: Diabetes has become the tsunami of non-communicable chronic diseases, with its alarmingly high prevalence largely driven by the global obesity epidemic. Achieving a healthy weight and preventing weight gain are integral components of optimal diabetes management. A modest weight loss of 5-10% is associated with significant reduction in blood sugar, lipid and blood pressure levels. Insulin detemir is an effective basal insulin analogue associated with less weight gain compared with both insulin NPH and insulin glargine. Once-daily insulin detemir could be considered an effective therapy for people with type 2 diabetes on lifestyle interventions and oral anti-diabetic agent therapy who require insulin.
authors.affiliation: Julia McFarlane Diabetes Research Centre, University of Calgary, Alberta, Canada. dcwlau@ucalgary.ca
authors.forename: David C W
authors.initials: DC
authors.lastname: Lau
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D004359:Drug Therapy, Combination; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D009765:Obesity / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin