title: Noncardiac chest pain and fibromyalgia.
abstract: Fibromyalgia (FM) remains an enigmatic and challenging clinical entity to manage, given its far-reaching spectrum of symptoms, chronicity, associated psychopathology, and lack of clinically available diagnostic tests. However, recent insights into the pathophysiology of FM offer hope that this condition, as with all members of the central sensitization syndromes, can be more readily diagnosed, measured, and treated. This paper presents the epidemiology features and pathogenesis of FM in the context of evaluating NCCP as a prototype among central pain sensitization syndromes. Evidence for the multimodality approach to treatment of this condition is also presented.
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo College of Medicine, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA. almansa.cristina@mayo.edu <almansa.cristina@mayo.edu>
authors.forename: Cristina
authors.initials: C
authors.lastname: Almansa
authors.forename: Benjamin
authors.initials: B
authors.lastname: Wang
authors.forename: Sami R
authors.initials: SR
authors.lastname: Achem
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D015928:Cognitive Behavioral Therapy; D000529:Complementary Therapies; D003937:Diagnosis, Differential; D005081:Exercise Therapy; D005356:Fibromyalgia / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006801:Humans
chemical_list: D000700:Analgesics; D000928:Antidepressive Agents