title: Quantification of condylar resorption in temporomandibular joint osteoarthritis.
abstract: OBJECTIVE
  This study was performed to determine the condylar morphologic variation of osteoarthritic (OA) and asymptomatic temporomandibular joints (TMJs) and to determine its correlation with pain intensity and duration.
  
  
  METHODS
  Three-dimensional surface models of mandibular condyles were constructed from cone-beam computerized tomography images of 29 female patients with TMJ OA (Research Diagnostic Criteria for Temporomandibular Disorders group III) and 36 female asymptomatic subjects. Shape correspondence was used to localize and quantify the condylar morphology. Statistical analysis was performed with multivariate analysis of covariance analysis, using Hotelling T(2) metric based on covariance matrices, and Pearson correlation.
  
  
  RESULTS
  The OA condylar morphology was statistically significantly different from the asymptomatic condyles (P < .05). Three-dimensional morphologic variation of the OA condyles was significantly correlated with pain intensity and duration.
  
  
  CONCLUSIONS
  Three-dimensional quantification of condylar morphology revealed profound differences between OA and asymptomatic condyles, and the extent of the resorptive changes paralleled pain severity and duration.
authors.affiliation: Department of Orthodontics, University of North Carolina School of Dentistry, Chapel Hill, North Carolina 27599, USA. cevidanl@dentistry.unc.edu
authors.forename: L H S
authors.initials: LH
authors.lastname: Cevidanes
authors.forename: A-K
authors.initials: AK
authors.lastname: Hajati
authors.forename: B
authors.initials: B
authors.lastname: Paniagua
authors.forename: P F
authors.initials: PF
authors.lastname: Lim
authors.forename: D G
authors.initials: DG
authors.lastname: Walker
authors.forename: G
authors.initials: G
authors.lastname: Palconet
authors.forename: A G
authors.initials: AG
authors.lastname: Nackley
authors.forename: M
authors.initials: M
authors.lastname: Styner
authors.forename: J B
authors.initials: JB
authors.lastname: Ludlow
authors.forename: H
authors.initials: H
authors.lastname: Zhu
authors.forename: C
authors.initials: C
authors.lastname: Phillips
mesh_terms: D000328:Adult; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000473:pathology*; D002508:Cephalometry / Q000379:methods / Q000706:statistics & numerical data; D054893:Cone-Beam Computed Tomography / Q000379:methods / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods / Q000706:statistics & numerical data; D021621:Imaging, Three-Dimensional / Q000379:methods / Q000706:statistics & numerical data; D008335:Mandibular Condyle / Q000000981:diagnostic imaging / Q000473:pathology*; D015588:Observer Variation; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000473:pathology*; D054850:Osteophyte / Q000000981:diagnostic imaging / Q000473:pathology; D010147:Pain Measurement; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013705:Temporomandibular Joint Disorders / Q000000981:diagnostic imaging / Q000473:pathology*; D013997:Time Factors; D014584:User-Computer Interface; D055815:Young Adult
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