title: The importance of taxon sampling in genomic studies: an example from the cyclooxygenases of teleost fishes.
abstract: Comparative genomic studies must often rely on single model species and exemplars to represent the genetic variation both within and among different major groups, because of technological, financial, and time constraints. This study of the cyclooxygenases from teleost fishes serves as a reminder that caution is required in these cases, since such incomplete taxon sampling can lead to errors in the interpretation and prediction of genome evolution, function, and structure.
authors.affiliation: Department of Biology, University of Florida, Gainesville, FL 32611-8525, USA. jhavird@ufl.edu
authors.forename: Justin C
authors.initials: JC
authors.lastname: Havird
authors.forename: Michael M
authors.initials: MM
authors.lastname: Miyamoto
mesh_terms: D000818:Animals; D001499:Bayes Theorem; D055028:Comparative Genomic Hybridization; D019143:Evolution, Molecular; D005399:Fishes / Q000145:classification / Q000235:genetics*; D016013:Likelihood Functions; D008957:Models, Genetic; D010802:Phylogeny; D011451:Prostaglandin-Endoperoxide Synthases / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D011451:Prostaglandin-Endoperoxide Synthases