Experimental modeling of viral diseases of the locomotor system.
Dissemination of infectious inflammation was studied in experimental influenza and acute and chronic herpesvirus infections. The possibility of articular involvement into the infectious process was evaluated. Pathomorphological signs of changes in the articular tissue confirmed the effects of these viruses on the locomotor pathology. Results of virus infection simulation in experimental animals suggest this model for studies of the pathogenesis of diseases of viral etiology (including those with articular involvement) in humans.
Malchikov
I A
IA
Ekaterinburg Institute of Viral Infections; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia. virus@etel.ru
Glinskikh
N P
NP
Tuzankina
I A
IA
Grigoryeva
J V
JV
Slobodenyuk
V K
VK
Tulakina
L G
LG
D000818:Animals; D004195:Disease Models, Animal; D006566:Herpesviridae Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary; D006801:Humans; D007251:Influenza, Human / Q000276:immunology / Q000473:pathology; D007592:Joint Diseases / Q000473:pathology / Q000662:veterinary / Q000821:virology; D007596:Joints / Q000473:pathology / Q000821:virology; D051379:Mice; D009043:Motor Activity / Q000502:physiology*; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary