title: [Crohn's disease: genetic aspects].
abstract: The paper deals with the topical problem of modern gastroenterology and coloproctology--the influence of genetic factors on the development and course of Crohn's disease (CD). It presents the data of foreign authors and the results of Russia 's first study evaluating the effect of the major polymorphic variants of the NOD2/CARD15 gene predisposing to CD on the risk, course, and other features of CD.
authors.forename: I D
authors.initials: ID
authors.lastname: Loranskaia
authors.forename: E V
authors.initials: EV
authors.lastname: Stepanova
mesh_terms: D003424:Crohn Disease / Q000453:epidemiology / Q000235:genetics* / Q000378:metabolism; D004247:DNA / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D009017:Morbidity; D053473:Nod2 Signaling Adaptor Protein / Q000235:genetics*; D011110:Polymorphism, Genetic; D012426:Russia
chemical_list: C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein; D004247:DNA