Aerosol fabrication of hollow mesoporous silica nanoparticles and encapsulation of L-methionine as a candidate drug cargo.
Hollow spherical nanoparticles with ordered mesoporous silica shells were fabricated by evaporation-induced self-assembly using (NH(4))(2)SO(4) and cetyltrimethyl ammonium bromide (CTAB) as templates. The model drug, L-methionine, was encapsulated within the spherical void at high loadings by repeated crystallization.
Jiang
Xingmao
X
Department of Chemical and Nuclear Engineering and Center for Micro-Engineered Materials, The University of New Mexico, Albuquerque, NM 87131, USA.
Ward
Timothy L
TL
Cheng
Yung-Sung
YS
Liu
Juewen
J
Brinker
C Jeffrey
CJ
D000336:Aerosols / Q000737:chemistry*; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D003460:Crystallization; D004337:Drug Carriers; D008715:Methionine / Q000008:administration & dosage / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*
D000336:Aerosols; D002593:Cetrimonium Compounds; D004337:Drug Carriers; D012822:Silicon Dioxide; D008715:Methionine; D000077286:Cetrimonium