Ratio of early mitral inflow peak velocity to flow propagation velocity predicts training effects of cardiac rehabilitation in patients after acute myocardial infarction.
OBJECTIVE
To use the ratio of early mitral inflow peak velocity (E) to mitral flow propagation velocity (FPV) measured in the early phase of myocardial infarction (early phase E/FPV) to evaluate the training effects of 8 weeks' cardiopulmonary rehabilitation in patients post-myocardial infarction.


METHODS
Single-blinded, randomized control trial.


METHODS
Eighty-seven patients with acute myocardial infarction who had undergone primary coronary intervention.


METHODS
Participants were enrolled randomly to either the cardiac rehabilitation or the control group. The rehabilitation group followed an 8-week supervised rehabilitation programme. All patients completed exercise testing and echo- cardiography at both the beginning and at 8-week follow-up.


RESULTS
The value of E/FPV was significantly reduced at 8-week follow-up in the rehabilitation group (p = 0.005). After cardiac rehabilitation, the increase in peak V(O2) (p = 0.002) and cardiac clinical outcome (composition of mortality, cardiac readmission rate, and revascularization rate) (p = 0.001) were significantly greater in patients with an early phase E/FPV < 1.5 than in patients with early phase E/FPV >or= 1.5. There were no significant differences in the increase in peak V (O2) and cardiac clinical outcome in patients with early phase E/FPV >or= 1.5.


CONCLUSIONS
Early phase E/FPV < 1.5 predicts more beneficial effects of cardiac rehabilitation in post-acute myocardial infarction patients who have undergone primary coronary intervention.
Chung
Cheng-Chih
CC
Cardiovascular Medical Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Huang
Wei-Chun
WC
Chiou
Kuan-Rau
KR
Lin
Ko-long
KL
Kuo
Feng-Yu
FY
Cheng
Chin-Chang
CC
Hsiao
Shih-Hung
SH
Liu
Chun-Peng
CP
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D004452:Echocardiography; D005080:Exercise Test; D005081:Exercise Therapy; D017079:Exercise Tolerance / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology; D009203:Myocardial Infarction / Q000503:physiopathology / Q000534:rehabilitation* / Q000628:therapy; D010101:Oxygen Consumption / Q000502:physiology; D011379:Prognosis; D016037:Single-Blind Method; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000502:physiology