title: Eruptive disseminated porokeratosis associated with internal malignancies: a case report.
abstract: Porokeratosis is a chronic skin disorder characterized by the presence of patches with elevated, thick, keratotic borders histologically featuring cornoid lamella. While porokeratosis usually is clinically defined by a slow onset, an eruptive variant has been reported. We report a 77-year-old woman affected by pancreatic carcinoma with-eruptive disseminated porokeratosis (EDP). We reviewed published cases of EDP developing suddenly or within a few months and found a total of 16 patients, 6 with internal malignancies of the liver or gastrointestinal tract. These findings suggest that patients with EDP should be investigated for the presence of internal malignancies.
authors.affiliation: Department of Biomedical and Surgical Sciences, University of Verona, Italy. donatella.schena@azosp.vr.it
authors.forename: Donatella
authors.initials: D
authors.lastname: Schena
authors.forename: Anastasia
authors.initials: A
authors.lastname: Papagrigoraki
authors.forename: Anna
authors.initials: A
authors.lastname: Frigo
authors.forename: Giampiero
authors.initials: G
authors.lastname: Girolomoni
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D010257:Paraneoplastic Syndromes / Q000473:pathology; D017499:Porokeratosis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy