title: Non-enzymatic amperometric glucose biosensor based on nickel hexacyanoferrate nanoparticle film modified electrodes.
abstract: A non-enzymatic amperometric glucose biosensor based on the modification of functional nickel hexacyanoferrate nanoparticles was prepared via electrochemical deposition. The electrochemical deposition of the nickel hexacyanoferrate nanoparticles was obtained by potential cycling in a solution containing nickel (II) and hexacyanoferrate (III) producing a modified surface with a high degree of uniformity. The modified electrode is exemplified towards the non-enzymatic sensing of glucose where using cyclic voltammetry and amperometry, low micro-molar up to milli-molar glucose concentrations are readily detectable. The non-enzymatic sensing of glucose also shows a modest selectivity over ascorbic acid. This platform offers a novel route for glucose sensors with wide analytical applications.
authors.affiliation: College of Material Science and Engineering, Sichuan University, Chengdu, Sichuan 610064, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Craig E
authors.initials: CE
authors.lastname: Banks
authors.forename: Qiyuan
authors.initials: Q
authors.lastname: Chen
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Ji
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D005295:Ferrocyanides / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D009532:Nickel / Q000737:chemistry*; D015203:Reproducibility of Results; D013499:Surface Properties
chemical_list: D005295:Ferrocyanides; C116383:ferrocyn; D009532:Nickel; D005947:Glucose; D001205:Ascorbic Acid