Coronary artery anomalies: detection on coronary artery calcium scoring scan.
OBJECTIVE
The objective of this study was to evaluate the accuracy of coronary artery calcium scanning in identifying coronary anomalies and potentially high-risk interarterial courses.


METHODS
Ninety-five consecutive patients who were diagnosed with a coronary anomaly on CT coronary angiography were enrolled, and 95 age- and sex-matched individuals in whom any coronary anomalies were excluded on CT coronary angiography were used as control subjects (total, 190 patients; 106 men and 84 women; mean age, 58 +/- 12 years). The coronary artery calcium scan for each patient was retrospectively evaluated by three radiologists for the presence of coronary anomalies and the presence of an interarterial course in cases of suspected anomaly. Interobserver agreement was assessed. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a coronary artery calcium scan for coronary anomalies and their interarterial courses were calculated, with CT coronary angiography as the reference standard.


RESULTS
Almost perfect interobserver agreement was achieved in evaluating coronary anomalies and interarterial courses (kappa = 0.81 and 0.92, respectively). We achieved a high grade of diagnostic performance of coronary artery calcium scanning in detecting coronary anomalies (sensitivity, 79-80%; specificity, 95-98%; PPV, 94-97%; and NPV, 82-83%) and interarterial courses (sensitivity, 88-91%; specificity, 95-97%; PPV, 84-91%; and NPV, 97%).


CONCLUSIONS
Coronary anomalies and interarterial courses were detected with great accuracy on coronary artery calcium scans.
Lee
Hye-Jeong
HJ
Department of Diagnostic Radiology, Severance Hospital, Yonsei University College of Medicine, Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
Kim
Young Jin
YJ
Hur
Jin
J
Nam
Ji Eun
JE
Kim
Tae Hoon
TH
Choe
Kyu Ok
KO
Choi
Byoung Wook
BW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002114:Calcinosis / Q000453:epidemiology*; D015897:Comorbidity; D017023:Coronary Angiography / Q000706:statistics & numerical data*; D003324:Coronary Artery Disease / Q000453:epidemiology*; D003330:Coronary Vessel Anomalies / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D018570:Risk Assessment; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*