title: [Periampullar diverticulum--related to bilio-pancreatic disorders].
abstract: Periampullar diverticulum (PAD) represent a particular type of duodenal diverticulum, with important pathological effect on the functionality of both the billiary tree and the pancreas. In our retrospective, randomised study, we analised 204 patients who underwent ERCP. We diagnosed 34 PAD (17%). We performed the endoscopic procedure for several pathological conditions of the biliary tract (cholestasis, jaundice, angiocolitis). Most DPA were identified in patients over 60 years (80%), beeing slightly more frequent in males (59%). We found in 25% of patients (over 65 years) with bile duct stones at least one PAD. Over 50% of patients with PAD had bile duct stones. Fibrous, obstructive papillo-odditis was found in 37% of patients with PAD.
  
  
  CONCLUSIONS
  1. PAD are related to bilio-pancreatic disorders, especially to bile duct stones. 2. The most common physio-pathological mechanism is a alteration of the bile flow, due to angulation, compression and/or obstruction of the final part of the bile duct and Wirsung duct, followed by secondary upper stasis. 3. Papillosphincterotomy has technical particularities, because of difficulties in incision orientation (a deformed papilla, with modified anatomical relationships, being situated profound inside the diverticulum cavity). Sphincterotomy depth was limited, which lead to less succesfull extraction of bile stones (89%, compared to the control group 92%). 4. We did not encounter major accidents. Secondary acute pancreatitis after ERCP was similar in both study groups. There was no significant difference in morbidity and mortality rates in both groups.
authors.affiliation: Clinica Chirurgie I, Spitalul Universitar de Urgenţă, Bucureşti. mihaigri@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Grigoriu
authors.forename: R
authors.initials: R
authors.lastname: Palade
authors.forename: C
authors.initials: C
authors.lastname: Lutic
mesh_terms: D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001660:Biliary Tract Diseases / Q000150:complications*; D016022:Case-Control Studies; D002760:Cholangiopancreatography, Endoscopic Retrograde; D004240:Diverticulum / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D004378:Duodenal Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D004384:Duodenoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000150:complications*; D012189:Retrospective Studies; D009803:Sphincter of Oddi / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D016717:Sphincterotomy, Endoscopic / Q000379:methods; D016896:Treatment Outcome