Comparative characteristics of nuclear ploidy of cells in endocrine and solid pseudopapillary tumors of the pancreas.
We carried out comparative morphometry and densitometry of cell nuclei in endocrine and solid pseudopapillary tumors and of exocrinocytes and endocrinocytes of the adjacent pancreatic tissue. The nuclear size, perimeters, and DNA content were higher in tumor cells. The index of proliferative activity, coefficient of aneuploidy, and histograms of DNA content in cell nuclei are recommended as additional criteria for differential diagnosis between endocrine and solid pseudopapillary tumors.
Podgornova
M N
MN
Department of Pathology, A. V. Vishnevsky Institute of Surgery, Moscow, Russia.
Dubova
E A
EA
Shchyogolev
A I
AI
D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000235:genetics / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology / Q000648:ultrastructure; D049109:Cell Proliferation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000235:genetics / Q000473:pathology; D011003:Ploidies; D012189:Retrospective Studies; D055815:Young Adult