title: Two cases of upper-extremity swelling: Paget-Schroetter syndrome and non-Hodgkin lymphoma.
abstract: Two adolescents presented to our emergency department with isolated, acute onset upper-extremity swelling. In their initial emergency department evaluations, both patients were found to have a deep venous thrombosis. Despite their similar presentations, the etiologies of their deep venous thrombosis were very different. After further evaluation, one patient was diagnosed with Paget-Schroetter syndrome and the other with non-Hodgkin lymphoma. These cases illustrate the importance of maintaining a broad differential diagnosis and using a multidisciplinary approach to patients with the unusual and potentially life-threatening presentation of upper-extremity swelling.
authors.affiliation: Department of Pediatric Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. dhillon.ravneet@mayo.edu
authors.forename: Ravneet K
authors.initials: RK
authors.lastname: Dhillon
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Spahr
mesh_terms: D000293:Adolescent; D000800:Angioplasty, Balloon; D004487:Edema / Q000209:etiology*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D008297:Male; D017131:Thrombectomy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D056824:Upper Extremity Deep Vein Thrombosis / Q000175:diagnosis* / Q000628:therapy; D020246:Venous Thrombosis / Q000209:etiology* / Q000628:therapy
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator