Time-dependent increases in cue-induced reinstatement of sucrose seeking after sucrose self-administration in adolescence.
Previously we reported that time-dependent increases in cue-induced reinstatement of cocaine seeking were attenuated in rats self-administering cocaine as adolescents, compared with adults (Li and Frantz (2009)). Now using sucrose self-administration, we report time-dependent increases in cue-induced reinstatement of sucrose seeking are similar across age groups, suggesting that age differences in reinstatement of cocaine seeking depend on specific effects of cocaine, not a compromised ability among younger rats to associate cues with rewards.
Li
Chen
C
Department of Biology, Neuroscience Institute, Georgia State University, Atlanta, GA 30302-5030, USA.
Frantz
Kyle J
KJ
D000375:Aging; D000704:Analysis of Variance; D000818:Animals; D001835:Body Weight; D003463:Cues; D019422:Dietary Sucrose / Q000008:administration & dosage*; D005108:Extinction, Psychological; D005247:Feeding Behavior; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012646:Self Administration; D013997:Time Factors
D019422:Dietary Sucrose