Metabolism of 14C-azoxystrobin in water at different pH.
Metabolism of (14)C-azoxystrobin was studied in water at pH 4, 7 and 9. The study suggested that volatilization losses of azoxystrobin were very low (3%) during 130 days of incubation. Only 2.5-4.2% of azoxystrobin was mineralised to CO(2) and pH of water did not have much effect on rate of mineralisation. The dissipation of azoxystrobin in water of all the three pHs followed first order kinetic with half-life values ranging from 143 to 158 d; degradation was the fastest at pH 9. Azoxystrobin acid, a major metabolite, was detected 4-7 day onwards and its concentration increased up to 130 days. The formation of azoxystrobin acid was more and faster under alkaline (pH 9) condition than neutral (pH 7) or acidic (pH 4) conditions.
Singh
Neera
N
Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, India.
Singh
Shashi B
SB
Mukerjee
Irani
I
Gupta
Suman
S
Gajbhiye
Vijay T
VT
Sharma
Praveen K
PK
Goel
Mayurika
M
Dureja
Prem
P
D002245:Carbon Dioxide; D002250:Carbon Radioisotopes; D004355:Drug Stability; D005659:Fungicides, Industrial / Q000032:analysis*; D006207:Half-Life; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008689:Methacrylates / Q000032:analysis*; D011743:Pyrimidines / Q000032:analysis*; D000073739:Strobilurins; D013997:Time Factors; D014835:Volatilization; D014867:Water / Q000032:analysis* / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification
D002250:Carbon Radioisotopes; D005659:Fungicides, Industrial; D008689:Methacrylates; D011743:Pyrimidines; D000073739:Strobilurins; D014874:Water Pollutants, Chemical; D014867:Water; D002245:Carbon Dioxide; C087670:azoxystrobin