title: Acute extrapyramidal disorder with bilateral reversible basal ganglia lesions in a diabetic uremic patient: diffusion-weighted imaging and spectroscopy findings.
abstract: Acute movement disorders associated with bilateral lesions in the basal ganglia are increasingly described in patients affected by diabetes and uremia. Pathophysiology has not been utterly understood yet, but it is likely to be multifactorial, with both ischemic/microvascular and metabolic/toxic factors determining the lesions and symptoms. We have studied a uremic diabetic patient who was admitted in emergency after presenting choreic movements, in which CT and MR, including diffusion-weighted imaging and spectroscopy, showed bilateral symmetric basal ganglia lesions with regression at follow-up. This is the first report in the literature describing spectroscopic findings in this condition.
authors.affiliation: Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy.
authors.forename: Franca
authors.initials: F
authors.lastname: Dicuonzo
authors.forename: Roberta
authors.initials: R
authors.lastname: Di Fede
authors.forename: Andrea
authors.initials: A
authors.lastname: Salvati
authors.forename: Michele
authors.initials: M
authors.lastname: Palma
authors.forename: Michele
authors.initials: M
authors.lastname: de Mari
authors.forename: Giuseppe Domenico
authors.initials: GD
authors.lastname: Baldassarre
authors.forename: Brigida
authors.initials: B
authors.lastname: Di Renzo
authors.forename: Carla
authors.initials: C
authors.lastname: Tortorella
mesh_terms: D001479:Basal Ganglia / Q000473:pathology*; D001480:Basal Ganglia Diseases / Q000150:complications*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D013057:Spectrum Analysis / Q000379:methods; D014511:Uremia / Q000150:complications*