title: FerriNaphth: a fluorescent chemodosimeter for redox active metal ions.
abstract: FerriNaphth, a fluorescent chemodosimeter for Fe(III), has been prepared and characterized. The probe consists of a catechol ligand linked to a naphthalimide fluorophore by an aniline nitrogen linker. Upon exposure to Fe(III), the aminocatechol of FerriNaphth is oxidized to the corresponding quinone, which in its imine-one tautomer, is hydrolyzed to liberate a fluorescent aminonaphthalimide derivative. The fluorescence behavior is consistent with oxidation being promoted by metal coordination.
authors.affiliation: Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.
authors.forename: Randy K
authors.initials: RK
authors.lastname: Jackson
authors.forename: Yu
authors.initials: Y
authors.lastname: Shi
authors.forename: Xudong
authors.initials: X
authors.lastname: Yao
authors.forename: Shawn C
authors.initials: SC
authors.lastname: Burdette
mesh_terms: D002396:Catechols / Q000737:chemistry; D005290:Ferric Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007477:Ions / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D053644:Naphthalimides / Q000737:chemistry; D010084:Oxidation-Reduction; D013050:Spectrometry, Fluorescence
chemical_list: D002396:Catechols; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D007477:Ions; D008670:Metals; D053644:Naphthalimides; C034221:catechol