title: Regio- and stereocontrol in rhenium-catalyzed transposition of allylic alcohols.
abstract: A hydroxyl group-directed, highly regio- and stereoselective transposition of allylic alcohols based on rhenium catalysis has been developed. The method is suitable for a direct isomerization of acetals into the thermodynamically preferred isomer as long as one of the hydroxyl groups is allylic. This method will expand the scope of rhenium-catalyzed alcohol transpositions for complex molecule synthesis.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106-9510, USA.
authors.forename: Aaron T
authors.initials: AT
authors.lastname: Herrmann
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Saito
authors.forename: Craig E
authors.initials: CE
authors.lastname: Stivala
authors.forename: Janine
authors.initials: J
authors.lastname: Tom
authors.forename: Armen
authors.initials: A
authors.lastname: Zakarian
mesh_terms: D002384:Catalysis; D020005:Propanols / Q000737:chemistry*; D012211:Rhenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D020005:Propanols; C006463:allyl alcohol; D012211:Rhenium
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