title: Comparative physiology of elemental distributions in plants.
abstract: BACKGROUND
  Plants contain relatively few cell types, each contributing a specialized role in shaping plant function. With respect to plant nutrition, different cell types accumulate certain elements in varying amounts within their storage vacuole. The role and mechanisms underlying cell-specific distribution of elements in plants is poorly understood.
  
  
  METHODS
  The phenomenon of cell-specific elemental accumulation has been briefly reviewed previously, but recent technological advances with the potential to probe mechanisms underlying elemental compartmentation have warranted an updated evaluation. We have taken this opportunity to catalogue many of the studies, and techniques used for, recording cell-specific compartmentation of particular elements. More importantly, we use three case-study elements (Ca, Cd and Na) to highlight the basis of such phenomena in terms of their physiological implications and underpinning mechanisms; we also link such distributions to the expression of known ion or solute transporters.
  
  
  CONCLUSIONS
  Element accumulation patterns are clearly defined by expression of key ion or solute transporters. Although the location of element accumulation is fairly robust, alterations in expression of certain solute transporters, through genetic modifications or by growth under stress, result in perturbations to these patterns. However, redundancy or induced pleiotropic expression effects may complicate attempts to characterize the pathways that lead to cell-specific elemental distribution. Accumulation of one element often has consequences on the accumulation of others, which seems to be driven largely to maintain vacuolar and cytoplasmic osmolarity and charge balance, and also serves as a detoxification mechanism. Altered cell-specific transcriptomics can be shown, in part, to explain some of this compensation.
authors.affiliation: School of Agriculture, Food, and Wine, University of Adelaide, Waite Campus, Glen Osmond, South Australia 5064, Australia. simon.conn@adelaide.edu.au
authors.forename: Simon
authors.initials: S
authors.lastname: Conn
authors.forename: Matthew
authors.initials: M
authors.lastname: Gilliham
mesh_terms: D004602:Elements; D010828:Physiology, Comparative; D010944:Plants / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D004602:Elements
references.citation: Ann Bot. 2009 Mar;103(5):665-72
references.pmid: 19182222
references.citation: Planta. 2004 Jul;219(3):507-14
references.pmid: 15085433
references.citation: Ann Bot. 2003 Oct;92(4):487-511
references.pmid: 12933363
references.citation: Plant Biol (Stuttg). 2006 Jul;8(4):419-29
references.pmid: 16906482
references.citation: Philos Trans R Soc Lond B Biol Sci. 2009 Jan 27;364(1514):195-201
references.pmid: 18957376
references.citation: Plant Physiol. 2005 Nov;139(3):1194-206
references.pmid: 16244156
references.citation: Plant J. 2007 Apr;50(1):159-75
references.pmid: 17397510
references.citation: Met Ions Biol Syst. 2005;44:97-144
references.pmid: 15971666
references.citation: Physiol Plant. 2008 Aug;133(4):651-69
references.pmid: 18724408
references.citation: Planta. 2007 Jan;225(2):403-11
references.pmid: 16845524
references.citation: Plant Physiol. 2009 Sep;151(1):210-22
references.pmid: 19571313
references.citation: J Biol Chem. 2003 Feb 21;278(8):6610-7
references.pmid: 12496310
references.citation: J Exp Bot. 2008;59(10):2697-706
references.pmid: 18495637
references.citation: Plant Physiol. 2003 Jun;132(2):618-28
references.pmid: 12805592
references.citation: Plant J. 2006 Nov;48(3):342-53
references.pmid: 17052322
references.citation: Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4991-6
references.pmid: 10781110
references.citation: New Phytol. 2007;175(3):387-404
references.pmid: 17635215
references.citation: J Exp Bot. 2003 Feb;54(383):657-61
references.pmid: 12554708
references.citation: Plant Cell. 2005 Jul;17(7):1908-25
references.pmid: 15937229
references.citation: Biochimie. 2006 Nov;88(11):1707-19
references.pmid: 16914250
references.citation: J Exp Bot. 2007;58(7):1559-69
references.pmid: 17355948
references.citation: Plant Physiol. 2004 Sep;136(1):2438-42
references.pmid: 15375199
references.citation: Proc Natl Acad Sci U S A. 1996 May 28;93(11):5489-94
references.pmid: 8643602
references.citation: Plant Mol Biol. 2007 Jul;64(5):531-8
references.pmid: 17476573
references.citation: Plant Physiol. 1999 Jan;119(1):305-12
references.pmid: 9880373
references.citation: Plant Cell. 2003 Feb;15(2):347-64
references.pmid: 12566577
references.citation: Environ Exp Bot. 2000 Nov 1;44(3):171-183
references.pmid: 11064038
references.citation: Trends Plant Sci. 2002 Mar;7(3):118-25
references.pmid: 11906835
references.citation: Cell Biochem Biophys. 1999;31(1):19-48
references.pmid: 10505666
references.citation: Plant Cell Rep. 2009 Sep;28(9):1341-9
references.pmid: 19533143
references.citation: J Exp Bot. 2001 May;52(358):891-9
references.pmid: 11432906
references.citation: New Phytol. 2008;179(3):712-721
references.pmid: 18554265
references.citation: Plant Physiol. 2003 Sep;133(1):126-34
references.pmid: 12970480
references.citation: Plant Physiol. 2004 Jan;134(1):118-28
references.pmid: 14657401
references.citation: Plant Cell Environ. 2006 Dec;29(12):2185-97
references.pmid: 17081251
references.citation: Plant Cell Environ. 2008 Jun;31(6):861-71
references.pmid: 18284583
references.citation: Plant Physiol. 2000 Jan;122(1):157-68
references.pmid: 10631259
references.citation: Nat Biotechnol. 2003 Jan;21(1):81-5
references.pmid: 12469134
references.citation: FEBS Lett. 2006 Feb 6;580(3):904-11
references.pmid: 16438971
references.citation: Planta. 1992 Jul;187(4):425-30
references.pmid: 24178135
references.citation: Nature. 1998 Jul 9;394(6689):192-5
references.pmid: 9671304
references.citation: Proc Natl Acad Sci U S A. 2000 May 23;97(11):6224-9
references.pmid: 10823962
references.citation: Plant J. 2003 Oct;36(2):229-39
references.pmid: 14535887
references.citation: Planta. 1991 Jun;184(3):327-33
references.pmid: 24194149
references.citation: Plant Physiol. 2007 Dec;145(4):1714-25
references.pmid: 17965172
references.citation: Plant Physiol. 2004 Apr;134(4):1793-802
references.pmid: 15064381
references.citation: Plant Physiol. 2004 Nov;136(3):3814-23
references.pmid: 15516513
references.citation: J Exp Bot. 2008;59(10):2875-90
references.pmid: 18552354
references.citation: New Phytol. 2006;171(4):751-7
references.pmid: 16918546
references.citation: Plant Cell Environ. 2008 Nov;31(11):1565-74
references.pmid: 18702634
references.citation: Biochim Biophys Acta. 2000 May 1;1465(1-2):52-78
references.pmid: 10748247
references.citation: Plant Physiol. 2007 Oct;145(2):317-29
references.pmid: 17675552
references.citation: FEBS Lett. 2008 Mar 19;582(6):967-76
references.pmid: 18307990
references.citation: J Mol Evol. 2006 Dec;63(6):815-25
references.pmid: 17086450
references.citation: Science. 2003 Dec 12;302(5652):1956-60
references.pmid: 14671301
references.citation: Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1431-5
references.pmid: 18202180
references.citation: New Phytol. 1993 Oct;125(2):367-372
references.pmid: 33874490
references.citation: Biochim Biophys Acta. 2000 May 1;1465(1-2):190-8
references.pmid: 10748254
references.citation: Science. 2008 May 16;320(5878):942-5
references.pmid: 18436742
references.citation: Annu Rev Plant Biol. 2008;59:709-33
references.pmid: 18251712
references.citation: J Exp Bot. 2006;57(6):1309-14
references.pmid: 16551689
references.citation: J Am Soc Hortic Sci. 2000 May;125(3):294-8
references.pmid: 11543566
references.citation: Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8782-6
references.pmid: 8710949
references.citation: Funct Plant Biol. 2007 May;34(4):314-331
references.pmid: 32689358
references.citation: Plant Physiol. 1972 May;49(5):794-7
references.pmid: 16658050
references.citation: Plant Cell Environ. 2008 Oct;31(10):1484-96
references.pmid: 18643900
references.citation: Plant Cell. 2002;14 Suppl:S401-17
references.pmid: 12045291
references.citation: Annu Rev Plant Biol. 2006;57:79-107
references.pmid: 16669756
references.citation: Plant J. 2002 Nov;32(4):539-48
references.pmid: 12445125
references.citation: Plant Physiol. 2008 Feb;146(2):529-38
references.pmid: 18162597
references.citation: Plant Physiol. 2004 Nov;136(3):3838-48
references.pmid: 15516511
references.citation: Planta. 1992 Jul;187(4):431-7
references.pmid: 24178136
references.citation: Plant Physiol Biochem. 2006 Jul-Sep;44(7-9):494-505
references.pmid: 17027276
references.citation: Plant Physiol. 1986 Sep;82(1):274-9
references.pmid: 16665005
references.citation: Plant Cell. 2009 Jul;21(7):2163-78
references.pmid: 19584143
references.citation: Proc Natl Acad Sci U S A. 2003 May 27;100(11):6872-7
references.pmid: 12738881
references.citation: Plant Mol Biol. 2001 Nov;47(5):633-40
references.pmid: 11725948
references.citation: Physiol Plant. 2009 Oct;137(2):155-65
references.pmid: 19758408
references.citation: Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12832-6
references.pmid: 11606781
references.citation: Funct Plant Biol. 2003 Jul;30(6):719-727
references.pmid: 32689056
references.citation: Plant Physiol. 2000 Mar;122(3):835-44
references.pmid: 10712547
references.citation: Plant Cell Physiol. 2008 Apr;49(4):540-8
references.pmid: 18281325
references.citation: Ann Bot. 2003 Apr;91(5):503-27
references.pmid: 12646496
references.citation: Planta. 2001 May;213(1):45-50
references.pmid: 11523655
references.citation: Trends Plant Sci. 2000 Nov;5(11):465-70
references.pmid: 11077254
references.citation: Plant Physiol. 1987 Oct;85(2):331-4
references.pmid: 16665697
references.citation: J Exp Bot. 2009;60(4):1333-47
references.pmid: 19297552
references.citation: J Exp Bot. 2001 Apr;52(356):541-9
references.pmid: 11373303
references.citation: Plant Physiol. 1984 Feb;74(2):430-3
references.pmid: 16663435
references.citation: J Exp Bot. 2001 Mar;52(Spec Issue):445-57
references.pmid: 11326051
references.citation: Plant Cell Environ. 2008 Sep;31(9):1325-34
references.pmid: 18518917
references.citation: Plant Physiol. 2001 Aug;126(4):1646-67
references.pmid: 11500563
references.citation: Plant Physiol. 1974 Sep;54(3):416-7
references.pmid: 16658902
references.citation: Science. 2004 Jun 18;304(5678):1811-4
references.pmid: 15166317
references.citation: Nat Biotechnol. 2003 Oct;21(10):1215-21
references.pmid: 12949535
references.citation: Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1665-77
references.pmid: 19433308
references.citation: Plant J. 2002 Oct;32(2):139-49
references.pmid: 12383080
references.citation: J Exp Bot. 2003 Sep;54(390):2035-43
references.pmid: 12925666
references.citation: Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11079-84
references.pmid: 9380762
references.citation: Curr Opin Plant Biol. 2005 Apr;8(2):174-82
references.pmid: 15752998
references.citation: Plant Cell Physiol. 2005 Nov;46(11):1848-54
references.pmid: 16179357
references.citation: Plant Biotechnol J. 2009 Apr;7(3):219-26
references.pmid: 19175521
references.citation: FEBS Lett. 2004 Oct 22;576(3):306-12
references.pmid: 15498553
references.citation: Environ Pollut. 2004 May;129(2):237-45
references.pmid: 14987809
references.citation: Plant Cell Physiol. 2001 Jan;42(1):74-84
references.pmid: 11158446
references.citation: Plant J. 2009 May;58(3):437-49
references.pmid: 19143998
references.citation: Plant Physiol. 2005 Aug;138(4):2048-60
references.pmid: 16055687
references.citation: Funct Plant Biol. 2002 Jan;29(12):1491-1499
references.pmid: 32688749
references.citation: Nat Biotechnol. 2001 Aug;19(8):765-8
references.pmid: 11479571
references.citation: Proteomics. 2009 May;9(10):2668-77
references.pmid: 19391183
references.citation: FEBS J. 2008 May;275(9):2267-82
references.pmid: 18397324
references.citation: Annu Rev Plant Biol. 2008;59:651-81
references.pmid: 18444910
references.citation: Plant Physiol. 2000 Sep;124(1):125-33
references.pmid: 10982428
references.citation: Plant Mol Biol. 1999 May;40(1):37-44
references.pmid: 10394943
references.citation: Science. 2007 Dec 14;318(5857):1789-92
references.pmid: 18084825
references.citation: PLoS One. 2007 Aug 08;2(8):e718
references.pmid: 17684564
references.citation: Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2135-40
references.pmid: 10051607
references.citation: PLoS Genet. 2009 May;5(5):e1000492
references.pmid: 19461889
references.citation: HFSP J. 2008 Aug;2(4):189-204
references.pmid: 19404430
references.citation: Methods Mol Biol. 2006;323:307-27
references.pmid: 16739587
references.citation: New Phytol. 2008;179(4):945-963
references.pmid: 18565144
references.citation: Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12081-6
references.pmid: 18697928
references.citation: Plant Physiol. 2003 Feb;131(2):676-83
references.pmid: 12586891
references.citation: Annu Rev Plant Biol. 2004;55:401-27
references.pmid: 15377226
references.citation: Plant Physiol. 2002 Dec;130(4):1815-26
references.pmid: 12481065
references.citation: Biochimie. 2006 Nov;88(11):1591-604
references.pmid: 17064836
references.citation: Plant Physiol. 2007 Apr;143(4):1918-28
references.pmid: 17322337
references.citation: Protoplasma. 2001;218(1-2):1-23
references.pmid: 11732314
references.citation: J Biol Chem. 2008 Feb 8;283(6):3497-3506
references.pmid: 18073213
references.citation: New Phytol. 2001 Oct;152(1):9-27
references.pmid: 35974475
references.citation: J Exp Bot. 2006;57(4):791-800
references.pmid: 16449377
references.citation: Plant Cell. 2002 Feb;14(2):465-77
references.pmid: 11884687
references.citation: J Exp Bot. 2002 Jan;53(366):1-11
references.pmid: 11741035
references.citation: New Phytol. 2009;182(1):49-84
references.pmid: 19192191
references.citation: Plant J. 2003 May;34(4):555-64
references.pmid: 12753593
references.citation: FEBS Lett. 2007 Aug 21;581(21):3943-9
references.pmid: 17662727
references.citation: Annu Rev Plant Physiol Plant Mol Biol. 2001 Jun;52:469-497
references.pmid: 11337406
references.citation: Biochem J. 2009 Aug 13;422(2):217-28
references.pmid: 19545236
references.citation: Ann Bot. 2008 Mar;101(4):485-9
references.pmid: 18089584
references.citation: Curr Opin Plant Biol. 2009 Jun;12(3):299-306
references.pmid: 19481498
references.citation: Int Rev Cytol. 2000;195:269-324
references.pmid: 10603578
references.citation: J Exp Bot. 2008;59(10):2793-801
references.pmid: 18562445
references.citation: Biochem Biophys Res Commun. 2009 May 8;382(3):637-41
references.pmid: 19306843
references.citation: Planta. 2004 Feb;218(4):615-22
references.pmid: 14663584
references.citation: Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12043-8
references.pmid: 9751787
references.citation: Curr Opin Plant Biol. 2001 Dec;4(6):540-9
references.pmid: 11641071
references.citation: Plant J. 2007 Nov;52(3):473-84
references.pmid: 17825054
references.citation: Nature. 2008 May 15;453(7193):391-5
references.pmid: 18425111
references.citation: J Exp Bot. 2001 Apr;52(356):623-30
references.pmid: 11373310
references.citation: Planta. 2007 Nov;226(6):1459-73
references.pmid: 17661078
references.citation: Planta. 2001 Mar;212(4):475-86
references.pmid: 11525504
references.citation: Plant Physiol. 2007 Feb;143(2):600-11
references.pmid: 17189337
references.citation: Plant J. 2005 Dec;44(6):928-38
references.pmid: 16359386
references.citation: Plant Physiol. 2005 Dec;139(4):1750-61
references.pmid: 16299177
references.citation: Annu Rev Plant Biol. 2006;57:451-75
references.pmid: 16669770
references.citation: Plant J. 2000 Jul;23(2):267-78
references.pmid: 10929120
references.citation: BMC Plant Biol. 2007 Apr 05;7:18
references.pmid: 17411438
references.citation: J Exp Bot. 2003 May;54(386):1431-46
references.pmid: 12709490
references.citation: Plant Physiol. 2004 Dec;136(4):4318-25
references.pmid: 15531711
references.citation: Ann Bot. 2005 Mar;95(4):571-81
references.pmid: 15642726
references.citation: Science. 1998 May 8;280(5365):918-21
references.pmid: 9572739
references.citation: Curr Opin Plant Biol. 2009 Jun;12(3):364-72
references.pmid: 19501016
references.citation: FEBS Lett. 2007 May 15;581(10):1993-9
references.pmid: 17467698
references.citation: Plant Methods. 2009 Sep 26;5:12
references.pmid: 19781097
references.citation: J Proteome Res. 2008 Oct;7(10):4209-10
references.pmid: 18785769
references.citation: Plant Methods. 2008 Feb 19;4:6
references.pmid: 18284694
references.citation: J Exp Bot. 2000 Jan;51(342):71-9
references.pmid: 10938797
references.citation: Plant Physiol. 2006 Aug;141(4):1653-65
references.pmid: 16798942
references.citation: J Exp Bot. 2006;57(5):1137-47
references.pmid: 16263900
references.citation: Planta. 2000 Dec;212(1):75-84
references.pmid: 11219586
references.citation: J Exp Bot. 2009;60(1):227-35
references.pmid: 19008410
references.citation: Plant Physiol. 2004 Jun;135(2):637-52
references.pmid: 15173570
references.citation: Curr Opin Plant Biol. 2003 Dec;6(6):617-21
references.pmid: 14611962
references.citation: New Phytol. 2009;181(1):35-52
references.pmid: 19076716
references.citation: Annu Rev Plant Biol. 2005;56:41-71
references.pmid: 15862089
references.citation: Plant Cell. 2004 Dec;16(12):3285-303
references.pmid: 15539469
references.citation: Lab Chip. 2009 Apr 7;9(7):917-24
references.pmid: 19294302
references.citation: J Exp Bot. 2009;60(9):2677-88
references.pmid: 19401409
references.citation: J Exp Bot. 2001 Dec;52(365):2291-300
references.pmid: 11709579
references.citation: Plant J. 2002 Jun;30(5):529-39
references.pmid: 12047628
references.citation: Curr Opin Plant Biol. 2009 Jun;12(3):339-46
references.pmid: 19501014
references.citation: Plant J. 2003 Sep;35(6):675-92
references.pmid: 12969422
references.citation: Annu Rev Plant Physiol Plant Mol Biol. 1999 Jun;50:133-161
references.pmid: 15012206
references.citation: Plant Physiol. 1994 Jul;105(3):799-813
references.pmid: 12232243
references.citation: J Exp Bot. 2001 Jul;52(360):1473-81
references.pmid: 11457907
references.citation: Plant Cell. 1999 Nov;11(11):2113-22
references.pmid: 10559438
references.citation: Plant Physiol. 2004 Feb;134(2):748-57
references.pmid: 14966248
references.citation: Biochem Biophys Res Commun. 2006 Jun 9;344(3):807-13
references.pmid: 16631619
references.citation: Curr Opin Plant Biol. 2009 Jun;12(3):291-8
references.pmid: 19481494
references.citation: Planta. 2005 Oct;222(3):418-27
references.pmid: 15864638
references.citation: Plant Physiol. 1994 Apr;104(4):1201-1208
references.pmid: 12232158
references.citation: New Phytol. 2007;175(4):655-674
references.pmid: 17688582
references.citation: Plant J. 2004 Jan;37(2):294-300
references.pmid: 14690512
references.citation: J Exp Bot. 2005 Feb;56(412):495-505
references.pmid: 15642711
references.citation: Plant Physiol. 2003 Jun;132(2):728-31
references.pmid: 12805601
references.citation: Plant Cell. 2007 Mar;19(3):1081-95
references.pmid: 17384171
references.citation: Plant Cell Environ. 2006 Dec;29(12):2228-37
references.pmid: 17081255
references.citation: J Exp Bot. 2005 Dec;56(422):3149-58
references.pmid: 16275670
references.citation: New Phytol. 2009 Jan;181(2):275-294
references.pmid: 19121028
references.citation: Physiol Plant. 2008 Nov;134(3):499-507
references.pmid: 18823330
references.citation: Plant Physiol. 2008 Aug;147(4):1774-87
references.pmid: 18567833
references.citation: Plant Cell Environ. 2003 Jun;26(6):789-800
references.pmid: 12803608
references.citation: Planta. 2008 Feb;227(3):659-69
references.pmid: 17968588
references.citation: Curr Opin Plant Biol. 2005 Dec;8(6):574-81
references.pmid: 16188489
references.citation: Biochem J. 2009 Feb 15;418(1):145-54
references.pmid: 18950291