title: Dengue virus surveillance for early warning, Singapore.
abstract: In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement within DENV-2 cosmopolitan genotype, which accompanied the predominant serotype switch, and cocirculation of multiple genotypes of DENV-3.
authors.affiliation: Environmental Health Institute, Singapore .
authors.forename: Kim Sung
authors.initials: KS
authors.lastname: Lee
authors.forename: Yee Ling
authors.initials: YL
authors.lastname: Lai
authors.forename: Sharon
authors.initials: S
authors.lastname: Lo
authors.forename: Timothy
authors.initials: T
authors.lastname: Barkham
authors.forename: Pauline
authors.initials: P
authors.lastname: Aw
authors.forename: Peng Lim
authors.initials: PL
authors.lastname: Ooi
authors.forename: Ji Choong
authors.initials: JC
authors.lastname: Tai
authors.forename: Martin
authors.initials: M
authors.lastname: Hibberd
authors.forename: Patrik
authors.initials: P
authors.lastname: Johansson
authors.forename: Seow Poh
authors.initials: SP
authors.lastname: Khoo
authors.forename: Lee Ching
authors.initials: LC
authors.lastname: Ng
mesh_terms: D000330:Aedes / Q000821:virology; D000818:Animals; D003715:Dengue / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D004196:Disease Outbreaks; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008969:Molecular Sequence Data; D009032:Mosquito Control; D010802:Phylogeny; D011159:Population Surveillance; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics; D017422:Sequence Analysis, DNA; D012703:Serotyping; D012846:Singapore / Q000453:epidemiology; D014759:Viral Envelope Proteins / Q000032:analysis / Q000235:genetics
chemical_list: D012367:RNA, Viral; D014759:Viral Envelope Proteins
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