Maternal and neonatal vitamin B12 deficiency detected through expanded newborn screening--United States, 2003-2007.
The incidence of neonatal vitamin B12 (cobalamin) deficiency because of maternal deficiency was determined by surveying state newborn screening programs. Thirty-two infants with nutritional vitamin B12 deficiency were identified (0.88/100,000 newborns). Pregnant women should be assessed for their risk of inadequate intake/malabsorption of vitamin B12.
Hinton
Cynthia F
CF
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. ceh9@cdc.gov
Ojodu
Jelili A
JA
Fernhoff
Paul M
PM
Rasmussen
Sonja A
SA
Scanlon
Kelley S
KS
Hannon
W Harry
WH
D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D008431:Maternal-Fetal Exchange; D009035:Mothers; D015997:Neonatal Screening / Q000379:methods*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D014806:Vitamin B 12 Deficiency / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology