[Preliminary study on genotype of hepatitis B virus detected from Xinjiang Uygur Autonomous Region in China].
OBJECTIVE
To determine the main genotype of hepatitis B virus (HBV) in Xinjiang.


METHODS
200 HBsAg positive serum specimens were detected from more than 2000 serum of Xinjiang inhabitants, and HBV S gene was detected by using nPCR amplifying, and compared with the standard S region HBV nucleotide sequences of genotypes A-H retrieved from GenBank, then analyzed and drawn the polygenetic tree by MEGA3 software.


RESULTS
Gene in 127 (63.5%) serum specimens was detected from 200 samples. Among 127 serum specimens, 10 (7.8%) was genotype B, 58 (45.7%) was genotype C, and 59 (46.5%) was genotype D.


CONCLUSIONS
Genotype B, C and D have been found in Xinjiang.
Fei
Yong-liang
YL
College of Veterinary Medicine, XinJiang Agricultural university, Urumqi 830052, China.
Yue
Cheng
C
Li
Lei
L
Yi
Yao
Y
Chen
Si-yong
SY
Jia
Zhi-yuan
ZY
Bi
Sheng-li
SL
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002681:China; D005260:Female; D005838:Genotype; D006509:Hepatitis B / Q000208:ethnology / Q000821:virology*; D006515:Hepatitis B virus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D012423:Rural Health; D055815:Young Adult