title: The effects of respiratory failure on delivery in pregnant patients with H1N1 2009 influenza.
abstract: BACKGROUND
  The majority of hospitalizations for H1N1 complications have been in people with high-risk comorbidities, including pregnancy. Here we describe the obstetric and critical care treatment of three patients with confirmed H1N1 influenza virus infection complicated by acute respiratory failure.
  
  
  METHODS
  We describe the clinical and therapeutic courses of three patients with confirmed H1N1 2009 influenza virus infection complicating singleton, twin, and triplet gestations, each of which were complicated by respiratory failure.
  
  
  CONCLUSIONS
  These three cases illustrate that a high index of suspicion, prompt treatment, timing and mode of delivery considerations, and interdisciplinary treatment are integral to the care of pregnant patients with H1N1 influenza infections complicated by acute respiratory failure.
authors.affiliation: From the Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, and the Department of Anesthesia, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Anahita
authors.initials: A
authors.lastname: Jafari
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Langen
authors.forename: Natali
authors.initials: N
authors.lastname: Aziz
authors.forename: Yair J
authors.initials: YJ
authors.lastname: Blumenfeld
authors.forename: Frederick
authors.initials: F
authors.lastname: Mihm
authors.forename: Maurice L
authors.initials: ML
authors.lastname: Druzin
mesh_terms: D000328:Adult; D003422:Critical Care; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000628:therapy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D012131:Respiratory Insufficiency / Q000453:epidemiology* / Q000628:therapy
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