title: Hidradenitis suppurativa complicating naevus comedonicus: the possible influence of mechanical stress on the development of hidradenitis suppurativa.
abstract: Naevus comedonicus is a rare, benign hamartoma consisting of grouped abnormal hair follicles and, occasionally, associated with other diseases. We describe an infant who developed hidradenitis-like lesions in an inguinal naevus comedonicus following increased mechanical stress on the region. It is speculated that the degree of strain on a hair follicle is increased when its diameter is increased, leading to wall ruptures. We hypothesise that this serendipitous observation provides a model for the way mechanical stress can account for the development of hidradenitis suppurativa in some patients.
authors.affiliation: Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Køgevej 7-13, Roskilde, Denmark. dndu@regionsjaelland.dk
authors.forename: Deirdre Nathalie
authors.initials: DN
authors.lastname: Dufour
authors.forename: Lars Erik
authors.initials: LE
authors.lastname: Bryld
authors.forename: Gregor B E
authors.initials: GB
authors.lastname: Jemec
mesh_terms: D002908:Chronic Disease; D005260:Female; D006119:Groin; D018859:Hair Follicle / Q000002:abnormalities*; D006222:Hamartoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D017497:Hidradenitis Suppurativa / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D013314:Stress, Mechanical