title: Bilateral intracranial electroencephalographic monitoring  immediately following corpus callosotomy.
abstract: Although many patients with medically refractory focal epilepsy are candidates for resective surgery, patients with multifocal epilepsy and symptomatic generalized epilepsy remain difficult to treat medically and surgically. Corpus callosotomy has been utilized since 1940 for the treatment of seizures, with reports of efficacy in multiple seizure types. Previous studies have demonstrated subsequent lateralization of bilateral/bisynchronous epileptiform activity following callosotomy. To investigate the efficacy of bilateral intracranial electroencephalographic studies immediately following corpus callosotomy, we retrospectively identified 26 patients who underwent corpus callosotomy at our center, 18 of whom had intracranial monitoring following corpus callosotomy. Five of the 18 had focal resections following intracranial electroencephalography (EEG). No patients were seizure free following callosotomy or resection. No differences in postoperative outcomes were seen between patients with intracranial EEG versus those without.
authors.affiliation: Department of Neurosurgery, New York University Langone Medical Center, New York, USA.
authors.forename: Alyson
authors.initials: A
authors.lastname: Silverberg
authors.forename: Kimberly
authors.initials: K
authors.lastname: Parker-Menzer
authors.forename: Orrin
authors.initials: O
authors.lastname: Devinsky
authors.forename: Werner
authors.initials: W
authors.lastname: Doyle
authors.forename: Chad
authors.initials: C
authors.lastname: Carlson
mesh_terms: D000293:Adolescent; D003337:Corpus Callosum / Q000503:physiopathology / Q000601:surgery*; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000379:methods / Q000706:statistics & numerical data*; D004827:Epilepsy / Q000503:physiopathology* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D011300:Preoperative Care / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D055536:Vagus Nerve Stimulation / Q000379:methods