T-lymphocyte production without the need for 'feeder cells' could prove promising for transplantation and regenerative medicine.
D000938:Antigen-Presenting Cells / Q000166:cytology; D049109:Cell Proliferation; D017690:Cell Transplantation; D054377:Chemokine CXCL12 / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D016867:Immunocompromised Host; D038041:Lymphopoiesis; D008562:Membrane Glycoproteins / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D054504:Precursor Cells, T-Lymphoid / Q000166:cytology / Q000276:immunology / Q000378:metabolism*; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000378:metabolism; D019718:Receptors, CXCR4 / Q000378:metabolism; D044968:Regenerative Medicine; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology / Q000378:metabolism*; D013950:Thymus Gland / Q000166:cytology / Q000378:metabolism
C527276:CXCR4 protein, human; D054377:Chemokine CXCL12; D008562:Membrane Glycoproteins; D016693:Receptors, Antigen, T-Cell, alpha-beta; D019718:Receptors, CXCR4; C090377:pre-T cell receptor alpha; D019869:Phosphatidylinositol 3-Kinases