Bioactive constituents from chinese natural medicines. XXXVI. Four new acylated phenylethanoid oligoglycosides, kankanosides J1, J2, K1, and K2, from stems of Cistanche tubulosa.
Four new acylated phenylethanoid oligoglycosides, kankanosides J(1) (1), J(2) (2), K(1) (3), and K(2) (4), were isolated from stems of Cistanche tubulosa (Orobanchaceae) together with isocampneoside I (5). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among them, 3-5 were found to inhibit D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes.
Pan
Yingni
Y
Pharmaceutical Research and Technology Institute, Kinki University, Higashi-osaka, Osaka, Japan.
Morikawa
Toshio
T
Ninomiya
Kiyofumi
K
Imura
Katsuya
K
Yuan
Dan
D
Yoshikawa
Masayuki
M
Muraoka
Osamu
O
D000818:Animals; D002478:Cells, Cultured; D031671:Cistanche / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005688:Galactosamine / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D006027:Glycosides; C550966:kankanoside; D005688:Galactosamine