title: [Comparison of in vitro release behavior of proanthocyanidins flexible nanoliposomes and general nanoliposomes].
abstract: OBJECTIVE
  To prepare flexible proanthocyanidins nanoliposomes, and explore the in vitro release behavior of proanthocyanidins flexible nanoliposomes and general nanoliposomes.
  
  
  METHODS
  Flexible proanthoeyanidins nanoliposomes were prepared proanthocyanidins using a film dispersion method, characterized by transmission electron microscope, and the in vitro release action was studied in different dissolution mediums using dynamic dialyse method with the content of total phenol as index.
  
  
  RESULTS
  The in vitro release of both proanthocyanidins flexible nanoliposomes and general nanoliposomes were in accordance with Weibull distribution.
  
  
  CONCLUSIONS
  Proanthocyanidins flexible nanoliposomes without pressure had similar in vitro release behavior with general nanoliposomes.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Chen
authors.forename: Huibin
authors.initials: H
authors.lastname: Wu
authors.forename: Junlin
authors.initials: J
authors.lastname: Yuan
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Rixian
authors.initials: R
authors.lastname: Jin
authors.forename: Huafeng
authors.initials: H
authors.lastname: Liu
authors.forename: Weizheng
authors.initials: W
authors.lastname: Xiong
authors.forename: Luqi
authors.initials: L
authors.lastname: Huang
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D008081:Liposomes / Q000737:chemistry / Q000648:ultrastructure; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D044945:Proanthocyanidins / Q000737:chemistry*
chemical_list: D008081:Liposomes; D044945:Proanthocyanidins