title: Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules.
authors.affiliation: Department of Chemistry and Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, The State University of New York, 657 Natural Sciences Complex, Buffalo, NY 14260, USA.
authors.forename: Sai Pradeep
authors.initials: SP
authors.lastname: Velagapudi
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Seedhouse
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Disney
mesh_terms: D000617:Aminoglycosides / Q000737:chemistry; D001483:Base Sequence; D008024:Ligands; D046228:Microarray Analysis; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D012313:RNA / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D000617:Aminoglycosides; D008024:Ligands; D012313:RNA
references.citation: Chem Rev. 2008 Apr;108(4):1171-224
references.pmid: 18361529
references.citation: RNA. 2008 Feb;14(2):390-4
references.pmid: 18065718
references.citation: J Am Chem Soc. 2008 Aug 20;130(33):11185-94
references.pmid: 18652457
references.citation: J Am Chem Soc. 2009 Jul 22;131(28):9767-79
references.pmid: 19552411
references.citation: ACS Chem Biol. 2007 Nov 20;2(11):745-54
references.pmid: 17975888
references.citation: Neurotherapeutics. 2008 Oct;5(4):592-600
references.pmid: 19019311
references.citation: Nat Biotechnol. 2006 Dec;24(12):1558-64
references.pmid: 17160062
references.citation: Nucleic Acids Res. 2009 Sep;37(17):5894-907
references.pmid: 19726586
references.citation: Expert Opin Ther Targets. 2007 Aug;11(8):1119-29
references.pmid: 17665982
references.citation: ACS Chem Biol. 2009 May 15;4(5):345-55
references.pmid: 19348464