title: After patients are diagnosed with knee osteoarthritis, what do they do?
abstract: OBJECTIVE
  To learn more about the health services and products that patients use after receiving a diagnosis of knee osteoarthritis (OA), as well as the trajectory of their health-related quality of life (HRQOL).
  
  
  METHODS
  Using a simple screening survey, community pharmacists identified 194 participants with previously undiagnosed knee OA. Of these participants, 190 were confirmed to have OA on further investigation. At baseline and 1, 3, and 6 months after diagnosis, a survey was administered to assess health services, product use, and HRQOL, including the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Medical Outcomes Study Short Form 36 (SF-36) health survey, the Paper Adaptive Test (PAT-5D-QOL), and the Health Utilities Index Mark 3.
  
  
  RESULTS
  With a mean age of 63 years, participants were mostly women, white, and overweight. By 6 months, more than 90% of the participants had visited their family physician to discuss their OA, and more than 50% of participants took either prescription or nonprescription analgesics. In addition, three-quarters of the participants started exercising, one-third initiated activity aids, and one-third had started natural medicine products. At 6 months compared with baseline, significant improvements were seen in the SF-36 physical component summary (P = 0.001) and bodily pain domain scores (P = 0.02), the PAT-5D-QOL overall, pain, and usual daily activities scores (P < 0.001 for all), and the WOMAC total, pain, and function scores (P < 0.001 for all).
  
  
  CONCLUSIONS
  Within 6 months of receiving a diagnosis of knee OA, participants made several lifestyle interventions, often without the advice of a health professional, and saw improvements in their pain and function.
authors.affiliation: University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Grindrod
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Marra
authors.forename: Lindsey
authors.initials: L
authors.lastname: Colley
authors.forename: Jolanda
authors.initials: J
authors.lastname: Cibere
authors.forename: Ross T
authors.initials: RT
authors.lastname: Tsuyuki
authors.forename: John M
authors.initials: JM
authors.lastname: Esdaile
authors.forename: Louise
authors.initials: L
authors.lastname: Gastonguay
authors.forename: Jacek
authors.initials: J
authors.lastname: Kopec
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001955:British Columbia; D002807:Chondroitin / Q000627:therapeutic use; D019587:Dietary Supplements; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D005944:Glucosamine / Q000627:therapeutic use; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009989:Orthotic Devices / Q000706:statistics & numerical data; D020370:Osteoarthritis, Knee / Q000188:drug therapy / Q000534:rehabilitation*; D010594:Pharmacies; D011788:Quality of Life; D040242:Risk Reduction Behavior; D012648:Self Care; D012720:Severity of Illness Index
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002807:Chondroitin; D005944:Glucosamine