title: Monomethylamine as a nitrogen source for a nonmethylotrophic bacterium, Agrobacterium tumefaciens.
abstract: Monomethylamine can be used by nonmethylotrophs as a sole nitrogen source but not as a carbon source; however, little is known about the genes and enzymes involved. The gamma-glutamylmethylamide/N-methylglutamate pathway for monomethylamine utilization by methylotrophs has recently been resolved. We have identified genes encoding key enzymes of this pathway in nonmethylotrophs (e.g., Agrobacterium tumefaciens) and demonstrated that this pathway is also involved in the utilization of monomethylamine as a nitrogen source by nonmethylotrophs.
authors.affiliation: Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
authors.forename: Yin
authors.initials: Y
authors.lastname: Chen
authors.forename: Kathryn L
authors.initials: KL
authors.lastname: McAleer
authors.forename: J Colin
authors.initials: JC
authors.lastname: Murrell
mesh_terms: D016960:Agrobacterium tumefaciens / Q000201:enzymology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D023061:Gene Order; D053858:Metabolic Networks and Pathways / Q000235:genetics; D008744:Methylamines / Q000378:metabolism*; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism*
chemical_list: D008744:Methylamines; D002244:Carbon; C027451:methylamine; D009584:Nitrogen
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