title: Short-term effects of periodontal therapy as an adjunct to anti-lipemic treatment.
abstract: OBJECTIVE
  This study was conducted to assess the effect of improved periodontal health following periodontal treatment on metabolic lipid control of patients on anti-lipemic treatment.
  
  
  METHODS
  The study population consisted of 20 patients aged 34-62 years with diagnoses of hyperlipidemia and chronic periodontitis. All patients used statin to treat their elevated levels of low-density lipoprotein cholesterol. Blood samples were obtained for measurement of serum lipids, fasting plasma glucose, and high sensitive C-reactive protein. Periodontal parameters, including plaque index, gingival index, probing pocket depth, clinical attachment level, and percentage of bleeding on probing, were evaluated. All parameters were assessed in each subject at baseline, after 3 months as a control (at the time of periodontal treatment), and 3 months after the non-surgical periodontal treatment that included scaling and root planning.
  
  
  RESULTS
  All lipid parameters decreased after the periodontal treatment, but only the decreases in total cholesterol and low-density lipoprotein cholesterol levels reached statistical significance compared to baseline (P = 0.002 and P = 0.003, respectively).
  
  
  CONCLUSIONS
  Improved periodontal health may influence metabolic control of hyperlipidemia and could be considered as an adjunct to the standard measures of hyperlipidemic patient care.
authors.affiliation: Department of Periodontology, Süleyman Demirel University, Faculty of Dentistry, Isparta, Turkey. ofentoglu@yahoo.com
authors.forename: O
authors.initials: O
authors.lastname: Fentoğlu
authors.forename: T
authors.initials: T
authors.lastname: Sözen
authors.forename: S G
authors.initials: SG
authors.lastname: Oz
authors.forename: B
authors.initials: B
authors.lastname: Kale
authors.forename: Y
authors.initials: Y
authors.lastname: Sönmez
authors.forename: M Oztürk
authors.initials: MO
authors.lastname: Tonguç
authors.forename: C A
authors.initials: CA
authors.lastname: Gürgan
authors.forename: Y
authors.initials: Y
authors.lastname: Aykaç
authors.forename: F Y
authors.initials: FY
authors.lastname: Kirzioğlu
mesh_terms: D000328:Adult; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D000069059:Atorvastatin; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D055113:Chronic Periodontitis / Q000628:therapy*; D003774:Dental Plaque Index; D012534:Dental Scaling; D005260:Female; D005500:Follow-Up Studies; D005884:Gingival Hemorrhage / Q000628:therapy; D006538:Heptanoic Acids / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009910:Oral Hygiene; D017622:Periodontal Attachment Loss / Q000628:therapy; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000628:therapy; D011758:Pyrroles / Q000627:therapeutic use; D016745:Root Planing; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood
chemical_list: D000924:Anticholesteremic Agents; D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011758:Pyrroles; D014280:Triglycerides; D002097:C-Reactive Protein; D002784:Cholesterol; D000069059:Atorvastatin