Maturation of auditory temporal integration and inhibition assessed with event-related potentials (ERPs).
BACKGROUND
We examined development of auditory temporal integration and inhibition by assessing electrophysiological responses to tone pairs separated by interstimulus intervals (ISIs) of 25, 50, 100, 200, 400, and 800 ms in 28 children aged 7 to 9 years, and 15 adults.


RESULTS
In adults a distinct neural response was elicited to tones presented at ISIs of 25 ms or longer, whereas in children this was only seen in response to tones presented at ISIs above 100 ms. In adults, late N1 amplitude was larger for the second tone of the tone pair when separated by ISIs as short as 100 ms, consistent with the perceptual integration of successive stimuli within the temporal window of integration. In contrast, children showed enhanced negativity only when tone pairs were separated by ISIs of 200 ms. In children, the amplitude of the P1 component was attenuated at ISIs below 200 ms, consistent with a refractory process.


CONCLUSIONS
These results indicate that adults integrate sequential auditory information into smaller temporal segments than children. These results suggest that there are marked maturational changes from childhood to adulthood in the perceptual processes underpinning the grouping of incoming auditory sensory information, and that electrophysiological measures provide a sensitive, non-invasive method allowing further examination of these changes.
Fox
Allison M
AM
School of Psychology, University of Western Australia, Perth, Australia. allison.fox@uwa.edu.au.
Anderson
Mike
M
Reid
Corinne
C
Smith
Tim
T
Bishop
Dorothy V M
DV
D000161:Acoustic Stimulation; D000328:Adult; D000375:Aging / Q000502:physiology*; D001303:Auditory Cortex / Q000254:growth & development*; D001306:Auditory Pathways / Q000254:growth & development; D001307:Auditory Perception / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology; D002648:Child; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009433:Neural Inhibition / Q000502:physiology; D009483:Neuropsychological Tests; D010470:Perceptual Masking / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013017:Sound Localization / Q000502:physiology*; D013997:Time Factors; D013998:Time Perception / Q000502:physiology*; D055815:Young Adult
Clin Neurophysiol. 2005 Aug;116(8):1747-53
16000258
J Speech Lang Hear Res. 2006 Oct;49(5):1104-13
17077218
Psychophysiology. 1997 Jan;34(1):32-8
9009806
Clin Neurophysiol. 2005 Jul;116(7):1695-706
15905124
PLoS One. 2008;3(12):e3929
19081790
Psychophysiology. 1991 Mar;28(2):240-4
1946890
Psychophysiology. 2004 Jul;41(4):636-42
15189486
J Speech Lang Hear Res. 2000 Dec;43(6):1402-15
11193961
J Cogn Neurosci. 2006 Jan;18(1):1-13
16417678
Cortex. 2005 Jun;41(3):327-41
15871598
Acta Otolaryngol. 2003 Jan;123(2):249-52
12701751
Clin Neurophysiol. 2005 Sep;116(9):2184-203
16043399
Psychophysiology. 1998 Jul;35(4):470-8
9643062
J Acoust Soc Am. 2003 May;113(5):2790-800
12765396
Int J Pediatr Otorhinolaryngol. 2008 Sep;72(9):1317-22
18584882
Dyslexia. 2003 Feb;9(1):37-45
12625375
Clin Neurophysiol. 2003 Dec;114(12):2307-25
14652090
Clin Neurophysiol. 2002 Mar;113(3):407-20
11897541
Psychophysiology. 1993 Jan;30(1):98-119
8416067
Psychophysiology. 2000 Mar;37(2):127-52
10731765
J Acoust Soc Am. 1995 Nov;98(5 Pt 1):2532-41
7593935
Psychophysiology. 1986 Nov;23(6):695-703
3823345
Brain Res. 2006 Dec 8;1124(1):126-41
17069776
Psychophysiology. 1987 Jul;24(4):375-425
3615753
Cereb Cortex. 2009 Oct;19(10):2290-7
19136454
Electroencephalogr Clin Neurophysiol Suppl. 1995;44:102-9
7649012
Clin Neurophysiol. 2000 Mar;111(3):388-97
10699397
Psychophysiology. 1997 May;34(3):308-16
9175445
Electroencephalogr Clin Neurophysiol. 1998 Jul;108(4):345-54
9714376
Clin Neurophysiol. 2000 Dec;111(12):2268-76
11090781
Child Dev. 1985 Jun;56(3):614-20
4006570
Electroencephalogr Clin Neurophysiol. 1996 May;100(3):220-8
8681863
Dev Sci. 2004 Sep;7(4):F11-8
15484585
Hear Res. 2008 Feb;236(1-2):61-79
18207681
Ear Hear. 2007 Dec;28(6):862-78
17982372
Psychophysiology. 2005 Nov;42(6):668-76
16364062
Nat Rev Neurosci. 2004 Nov;5(11):887-92
15496866
Psychophysiology. 1987 Jul;24(4):479-86
3615759
Neuropsychologia. 2009 Feb;47(3):771-85
19124031
J Speech Lang Hear Res. 2008 Aug;51(4):1002-15
18658067