title: Microenvironment and macroenvironment in hypertensive hearts: boundaries and silos--can we pick and treat diastolic heart failure?
authors.forename: Stephen Nicholas
authors.initials: SN
authors.lastname: Hunyor
authors.forename: Christopher John
authors.initials: CJ
authors.lastname: Jackson
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D005260:Female; D054144:Heart Failure, Diastolic / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D020781:Matrix Metalloproteinase 1 / Q000378:metabolism*; D009200:Myocardial Contraction / Q000502:physiology*; D009206:Myocardium / Q000473:pathology; D020097:Natriuretic Peptide, Brain / Q000378:metabolism; D011379:Prognosis; D012016:Reference Values; D018570:Risk Assessment; D013318:Stroke Volume / Q000502:physiology; D019714:Tissue Inhibitor of Metalloproteinases / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D019714:Tissue Inhibitor of Metalloproteinases; D020097:Natriuretic Peptide, Brain; D020781:Matrix Metalloproteinase 1