DNA gyrase and topoisomerase IV are dual targets of zabofloxacin in Streptococcus pneumoniae.
Park
Hee Soo
HS
Jung
Sung Ji
SJ
Kwak
Jin-Hwan
JH
Choi
Dong-Rack
DR
Choi
Eung-Chil
EC
D019943:Amino Acid Substitution / Q000235:genetics; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics; D027081:DNA Gyrase / Q000235:genetics; D027101:DNA Topoisomerase IV / Q000037:antagonists & inhibitors* / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests; D020125:Mutation, Missense; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000201:enzymology*; D059005:Topoisomerase II Inhibitors
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D059005:Topoisomerase II Inhibitors; D027101:DNA Topoisomerase IV; D027081:DNA Gyrase