title: Biological activities of polyphenols from grapes.
abstract: The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.
authors.affiliation: Department of Nutrition, Sun Yat-Sen University, Guangzhou, China. enqinxia@163.com
authors.forename: En-Qin
authors.initials: EQ
authors.lastname: Xia
authors.forename: Gui-Fang
authors.initials: GF
authors.lastname: Deng
authors.forename: Ya-Jun
authors.initials: YJ
authors.lastname: Guo
authors.forename: Hua-Bin
authors.initials: HB
authors.lastname: Li
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000633:toxicity; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects; D002316:Cardiotonic Agents / Q000737:chemistry / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects; D059808:Polyphenols / Q000737:chemistry* / Q000494:pharmacology; D017382:Reactive Oxygen Species / Q000737:chemistry / Q000378:metabolism; D027843:Vitis / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D002316:Cardiotonic Agents; D059808:Polyphenols; D017382:Reactive Oxygen Species
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