Recurrent Cerebral Venous Thrombosis Associated with Elevated Factor VIII.
Cerebral venous thrombosis (CVT) rarely recurs, and the factors associated with a recurrence remain unclear. Recently, however, elevated plasma coagulation factor VIII has been considered a factor related to recurrent venous thromboembolism. Here we report a patient who had recurrent CVT associated with significantly elevated levels of factor VIII despite the chronic use of an antiplatelet agent. Factor IX was also elevated in this patient. These findings suggest that elevated factor VIII is a factor underlying the recurrence of CVT, and that prolonged anticoagulation therapy may have to be considered in patients with elevated coagulation factor levels.
Kim
Mi Jung
MJ
Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Korea.
Cho
A-Hyun
AH
No
Young-Joo
YJ
Kim
Hee-Young
HY
Kim
Jong S
JS
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