title: [Clinical aspects of temporal arteritis: course variations up to fatal complications].
abstract: BACKGROUND
  Arteritis temporalis (AT) shows a variable course of the disease and may lead to transient or permanent visual loss.
  
  
  METHODS
  In a retrospective consecutive case series 66 patients with suspected AT were followed up of which 65 underwent arterial biopsy. Symptoms, therapy and complications were followed up.
  
  
  RESULTS
  Of the patients 32 (49.2%) revealed a positive histological finding in unilateral (55.4%) or bilateral (44.6%) biopsy. Of these 3 (9.4%) suffered a severe or fatal outcome: two with extensive ischemia of the vertebrobasilar system (one fatal) and one patient died due to acute pancreatitis, a rare side effect of systemic steroid therapy.
  
  
  CONCLUSIONS
  When systemically apparent, arteritis temporalis can progress to reduction of general health, cerebral ischemia and organ infarction. Therefore, AT is a serious disease requiring interdisciplinary, immediate diagnostics and prompt therapy.
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland, anne.brueggemann@uk-sh.de.
authors.forename: A
authors.initials: A
authors.lastname: Brüggemann
authors.forename: K
authors.initials: K
authors.lastname: Holl-Ulrich
authors.forename: M
authors.initials: M
authors.lastname: Müller
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness / Q000401:mortality*; D002545:Brain Ischemia / Q000401:mortality*; D015984:Causality; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005858:Germany / Q000453:epidemiology; D013700:Giant Cell Arteritis / Q000175:diagnosis* / Q000401:mortality*; D006304:Health Status; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000401:mortality*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D015996:Survival Rate
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