title: "The cancer bond": exploring the formation of cancer risk perception in families with Lynch syndrome.
abstract: This study explores the social context of hereditary cancer risk perception in three families, an African-American family, a Mexican-American family, and a Caucasian family, each with Lynch Syndrome documented by a mismatch repair gene mutation. Communication network assessments measured family communication about cancer experiences and genetic testing information among a total of 26 participants. Participant narratives were evaluated to gain insight into how family cancer experiences and genetic testing information have shaped perceptions of cancer risk. Analysis of communication networks indicated that some families discussed cancer experiences to a greater extent than genetic testing information, and vice-versa. Interviews elucidated that sharing both types of health information led participants to conceptualize linkages among a strong family history of cancer, genetic testing information, and cancer prevention strategies. Understanding how different types of family communication influence the formation of perceived hereditary disease risk may enhance efforts to tailor genetic counseling services for families.
authors.affiliation: Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. aunchalee.palmquist@yale.edu
authors.forename: Aunchalee E L
authors.initials: AE
authors.lastname: Palmquist
authors.forename: Laura M
authors.initials: LM
authors.lastname: Koehly
authors.forename: Susan K
authors.initials: SK
authors.lastname: Peterson
authors.forename: Margarette
authors.initials: M
authors.lastname: Shegog
authors.forename: Sally W
authors.initials: SW
authors.lastname: Vernon
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Gritz
mesh_terms: D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics / Q000523:psychology*; D003430:Cross-Sectional Studies; D005190:Family / Q000523:psychology*; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D012307:Risk Factors
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