What's the Point? How Point-of-Care STI Tests Can Impact Infected Patients.
Point-of-care (POC) tests are an important strategy to address the epidemic of sexually transmitted infections (STIs) among both adolescents and young adults. While access to care and confidentiality are major barriers to STI care, POC tests allow the clinician to provide immediate and confidential test results and treatment. In addition, POC test results constitute a "teachable moment"; that is, an opportunity to provide immediate feedback to the patient that may impact his/her risk behaviors. This paper reviews published data and manufacturer's product literature describing current point-of-care STI tests, including studies of test performance as well as impact on treatment intervals and disease spread. It presents theoretical and proposed pitfalls and solutions of implementing POC tests in clinical settings, non-traditional settings, and home care venues. We reviewed the available STI tests according to the World Health Organization (WHO) criteria for judging POC tests: the "ASSURRED" criteria (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free, Delivered).
Huppert
Jill
J
Division of Adoelscent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Hesse
Elizabeth
E
Gaydos
Charlotte A
CA
J Clin Microbiol. 1994 Jan;32(1):148-52
8126171
Sex Transm Infect. 2006 Dec;82 Suppl 5:v29-32
17215275
Curr Infect Dis Rep. 2006 Mar;8(2):115-24
16524548
Sex Transm Dis. 2007 Mar;34(3):180-2
16865052
J Clin Microbiol. 2006 May;44(5):1831-3
16672414
J Clin Microbiol. 2009 Jan;47(1):215-6
19005149
Sex Transm Infect. 2006 Dec;82 Suppl 5:v1-6
17151023
Infect Dis Obstet Gynecol. 2004;12(1):17-21
15460191
J Clin Virol. 2009 Jun;45(2):150-2
19451023
Sex Transm Dis. 1999 Apr;26(4):232-40
10225593
JAMA. 2004 May 12;291(18):2229-36
15138245
Am J Obstet Gynecol. 1996 Apr;174(4):1339-42
8623867
J Clin Microbiol. 1991 Sep;29(9):2086-8
1774342
JAMA. 2008 Aug 6;300(5):520-9
18677024
Clin Infect Dis. 2002 Sep 1;35(5):576-80
12173132
Obstet Gynecol. 2005 Feb;105(2):390-6
15684170
J Virol Methods. 2004 Jan;115(1):105-7
14656467
Perspect Sex Reprod Health. 2004 Jan-Feb;36(1):6-10
14982671
J Clin Microbiol. 2007 Oct;45(10):3281-5
17699650
J Clin Microbiol. 2009 Jan;47(1):59-63
18987174
Int J STD AIDS. 2002 Jan;13(1):22-4
11802925
Am J Public Health. 2000 Jun;90(6):974-6
10846519
Curr Opin Pediatr. 1996 Aug;8(4):333-7
8954263
Sex Transm Infect. 2005 Oct;81(5):408-14
16199741
Sex Transm Infect. 2006 Dec;82 Suppl 5:v26-8
17118954
J Clin Microbiol. 1991 Jul;29(7):1551-3
1885755
J Clin Microbiol. 1998 Nov;36(11):3205-10
9774566
AIDS. 2006 Aug 1;20(12):1655-60
16868447
Clin Diagn Lab Immunol. 2000 Jul;7(4):698-9
10882675
Clin Microbiol Infect. 1997 Feb;3(6):663-667
11864210
Clin Infect Dis. 2007 Jul 15;45(2):194-8
17578778
Clin Diagn Lab Immunol. 2003 Nov;10(6):1157-8
14607884
J Clin Microbiol. 2004 Jul;42(7):2940-3
15243042
Infect Dis Clin North Am. 2005 Jun;19(2):281-96
15963872
Clin Infect Dis. 2009 Aug 1;49(3):444-53
19538088
J Clin Microbiol. 2008 Oct;46(10):3467-9
18685008
BMJ. 2007 Dec 8;335(7631):1190-4
18055487
J Clin Microbiol. 2005 Feb;43(2):684-7
15695664
Sex Transm Dis. 2006 Jul;33(7):451-7
16652069
J Infect Dis. 2008 Feb 15;197(4):548-54
18275275
Obstet Gynecol. 2009 Jan;113(1):89-95
19104364
Sex Transm Infect. 2006 Dec;82 Suppl 5:v33-7
17121763
Sex Transm Infect. 2009 Jun;85(3):187-9
19398434
J Clin Microbiol. 1998 Aug;36(8):2183-6
9665987