[Dendritic cell function in response to schistosome infection].
Dendritic cells (DC) are uniquely specialised for both antigen acquisition and presentation, linking innate and adaptive immunity. Great progress has been made in DC biology and function recently. In the field of schistosomiasis, studies have revealed that a DC phenotype is quite distinct to that of conventional activation. Understanding the interaction between schistosomes and DC is therefore not only addressing fundamental questions of DC biology and immunity to multicellular parasites but also opening the way to therapeutic manipulation of the immune system.
Li
Xiao-hong
XH
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Tang
Lin-hua
LH
Cao
Jian-ping
JP
D000818:Animals; D003713:Dendritic Cells / Q000276:immunology* / Q000469:parasitology; D006790:Host-Parasite Interactions; D012552:Schistosomiasis / Q000276:immunology*