title: Efficiency and tolerability of artrofoon (ultralow doses and antibodies to TNF-alpha) in osteoarthrosis.
abstract: Antiinflammatory and analgesic effects of artrofoon in osteoarthritis and the absence of side effects were demonstrated. The maximum antiinflammatory effect was attained by the end of the 3rd month of artrofoon treatment. The effect persisted from 6 months to 2 years against the background of maintaining therapy with artroofoon.
authors.affiliation: Department of Rheumatology, Moscow State University of Medicine and Dentistry, Moscow.
authors.forename: B A
authors.initials: BA
authors.lastname: Alikhanov
authors.forename: A Yu
authors.initials: AY
authors.lastname: Pavlenko
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000276:immunology / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; C503436:Artrofoon; D014409:Tumor Necrosis Factor-alpha