Ene reactions between two alkynes? Doors open to thermally induced cycloisomerization of macrocyclic triynes and enediynes.
A domino process is described combining an ene reaction between two alkynes and a Diels-Alder cycloaddition of the vinylallene formed. The process accounts for the thermally induced cycloisomerization of macrocyclic triynes and enediynes to give fused tetracycles in a stereoselective manner.
González
Iván
I
Dept. de Química, Universitat de Girona (UdG), Campus de Montilivi, s/n, E-17071-Girona, Spain.
Pla-Quintana
Anna
A
Roglans
Anna
A
Dachs
Anna
A
Solà
Miquel
M
Parella
Teodor
T
Farjas
Jordi
J
Roura
Pere
P
Lloveras
Vega
V
Vidal-Gancedo
José
J