Impact of interim methadone maintenance on HIV risk behaviors.
The extent to which interim methadone (IM) without counseling reduces HIV risk behavior has not been reported. The AIDS Risk Assessment scale was administered at baseline and 4-month follow-up to 319 adult heroin-dependent participants randomly assigned to IM or waiting list. On an intent-to-treat basis, there was a significantly greater reduction in drug injection and unprotected sex while high from baseline to follow-up, favoring the IM condition. Remedying the shortage of methadone capacity through the expansion of IM would be a worthwhile approach to reducing the spread of HIV infection.
Wilson
Monique E
ME
Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA. mwilson@friendsresearch.org
Schwartz
Robert P
RP
O'Grady
Kevin E
KE
Jaffe
Jerome H
JH
D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009294:Narcotics / Q000627:therapeutic use*; D012309:Risk-Taking; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000534:rehabilitation*
D009294:Narcotics; D008691:Methadone
Arch Gen Psychiatry. 2006 Jan;63(1):102-9
16389204
J Subst Abuse Treat. 2009 Sep;37(2):138-50
19150206
J Acquir Immune Defic Syndr (1988). 1993 Sep;6(9):1049-56
8340896
Addiction. 2007 Nov;102(11):1816-23
17784892
J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):581-9
18645513
J Health Soc Behav. 1988 Sep;29(3):214-26
3241064
Drug Alcohol Depend. 1996 May;41(1):1-7
8793304
Am J Epidemiol. 2003 Oct 1;158(7):695-704
14507606
J Gen Intern Med. 2006 Feb;21(2):193-5
16336624
AIDS Educ Prev. 1993 Summer;5(2):121-30
8323854
J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Feb 1;11(2):198-202
8556403
J Subst Abuse Treat. 1994 Jul-Aug;11(4):367-72
7966507
J Subst Abuse Treat. 2006 Sep;31(2):187-94
16919747