title: Relapsed mantle cell lymphoma presenting as "sister Mary joseph nodule".
abstract: The finding of umbilical metastasis has historically been called a "Sister Mary Joseph Nodule". A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable response to chemotherapy, this patient experienced multiple relapses, despite aggressive chemotherapy regimens. This clinical course is characteristic of the mantle cell form of non-hodgkin's lymphoma and illustrates a need to seek out more effective therapies.
authors.affiliation: Department of Internal Medicine, University of Washington, Box 39892. 325 Ninth Ave., Seattle, WA 98104, USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Vaughn
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Gopal
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