Diagnosing microalbuminuria and consequences for the drug treatment of patients with type 2 diabetes: a European survey in primary care.
OBJECTIVE
To assess general practitioners (GPs) knowledge of guideline recommendations on diagnosing microalbuminuria (MA) and to evaluate how this diagnosis influences drug treatment of diabetes patients.


METHODS
A postal case-history based questionnaire describing a male patient (previously not tested for MA) with type 2 diabetes who had several risk markers for cardiovascular disease.


RESULTS
2078GPs from nine European countries were included, with response rates varying from 7% to 43%. Almost all GPs recommended annual testing for MA. Forty-five to 77% (depending on country) of GPs required more than one positive test to diagnose MA. The absolute increase in the percentages of GPs who would supplement the patient's drug treatment if MA developed was: for anginotensin converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) 23-50% (depending on country), for statins 0-19%, for acetylsalicylic acid 2-13%, and for hypoglycemic agents (tablets and insulin) 0-33%. The proportion of GPs recommending all four possible treatment modalities was low.


CONCLUSIONS
Guidelines for diagnosing MA were partly followed. ACEIs and ARBs were recommended when MA was present, but the recommended multifactorial treatment of cardiovascular risk markers was not implemented.
Aakre
Kristin M
KM
Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway. kristin.moberg.aakre@helse-bergen.no
Thue
Geir
G
Subramaniam-Haavik
Sumathi
S
Cooper
John
J
Bukve
Tone
T
Morris
Howard A
HA
Müller
Mathias
M
Lovrencic
Marijana V
MV
Plum
Inger
I
Kallion
Kaja
K
Aab
Alar
A
Kutt
Marge
M
Gillery
Philippe
P
Schneider
Nathalie
N
Horvath
Andrea R
AR
Onody
Rita
R
Oosterhuis
Wytze
W
Ricos
Carmen
C
Perich
Carmen
C
Nordin
Gunnar
G
Sandberg
Sverre
S
D000419:Albuminuria / Q000175:diagnosis* / Q000188:drug therapy*; D003625:Data Collection; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires