In vitro and in vivo evidence of pathogenic roles of Hic-5/ARA55 in keloids through Smad pathway and profibrotic transcription.
Inui
Shigeki
S
Shono
Fumie
F
Noguchi
Fumihito
F
Nakajima
Takeshi
T
Hosokawa
Ko
K
Itami
Satoshi
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017931:DNA Primers / Q000235:genetics; D005260:Female; D005347:Fibroblasts / Q000166:cytology; D005786:Gene Expression Regulation; D006801:Humans; D066298:In Vitro Techniques; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D007627:Keloid / Q000378:metabolism*; D060588:LIM Domain Proteins; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D017434:Protein Structure, Tertiary; D018125:Receptors, Transforming Growth Factor beta / Q000378:metabolism; D015398:Signal Transduction; D012867:Skin / Q000166:cytology; D014158:Transcription, Genetic; D016212:Transforming Growth Factor beta / Q000378:metabolism
D017931:DNA Primers; D047908:Intracellular Signaling Peptides and Proteins; D060588:LIM Domain Proteins; D018125:Receptors, Transforming Growth Factor beta; C490351:TGFB1I1 protein, human; D016212:Transforming Growth Factor beta