HIV-1 subtype C transmission network: the phylogenetic reconstruction strongly supports the epidemiological data.
The sequence and times of the transmission events was reported after a hospital accident by a phylodynamic reconstruction of transmission network among four subjects. The dated tree allowed to date the transmission events with good approximation, the time point and direction of each transmission, estimated on the basis of the phylogeny, and agreed with the presumptive time of infection on the basis of clinical history-taking.
Bon
Isabella
I
Microbiology Section of the Department of Haematology and Oncologic Sciences, University of Bologna, Via Massarenti, 9-40138 Bologna, Italy.
Ciccozzi
Massimo
M
Zehender
Gianni
G
Biagetti
Carlo
C
Verrucchi
Gabriella
G
Lai
Alessia
A
Lo Presti
Alessandra
A
Gibellini
Davide
D
Re
Maria Carla
MC
D016000:Cluster Analysis; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D017720:Molecular Epidemiology; D010802:Phylogeny; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA; D054302:pol Gene Products, Human Immunodeficiency Virus / Q000235:genetics
D054302:pol Gene Products, Human Immunodeficiency Virus