Pandemic influenza A (H1N1) 2009 with neurological manifestations, a case series.
OBJECTIVE
Describe a series of atypical presentations of pandemic influenza A (H1N1) 2009.


METHODS
Description of case series using hospital records.


RESULTS
Six patients aged 1 to 65 years with confirmed pandemic influenza A (H1N1) 2009 infection presented with neurological complications within 2 to 5 days after the first signs of influenza-like illness. All six were admitted with seizures or altered mental status. No abnormalities were found in brain scans or cerebral spinal fluid studies of any of the six. All were discharged without sequelae within days of admission.


CONCLUSIONS
This is only the second report of pandemic influenza presenting with neurological manifestations. Clinicians caring for patients when pandemic influenza is prevalent in their communities should maintain a high level of awareness of the potential atypical presentations with which this disease can appear.
Noriega
Luis Miguel
LM
Department of Medicine, Clínica Alemana de Santiago, Clínica Alemana School of Medicine, Universidad del Desarrollo, Santiago, Chile.
Verdugo
Renato J
RJ
Araos
Rafael
R
Munita
José Manuel
JM
Díaz
Violeta
V
Marcotti
Alejandra
A
Perez
Jorge
J
Gonzalez
Patricia
P
Thompson
Luis
L
Canals
Magdalena
M
Hoppe
Arnold
A
Mounts
Anthony W
AW
Vial
Pablo A
PA
D000293:Adolescent; D000328:Adult; D000368:Aged; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000209:etiology*
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