Primary meningeal sarcoma with leiomyoblastic differentiation complicating pregnancy.
Intracranial malignant tumors during pregnancy are rare. Primary meningeal sarcoma with leiomyoblastic differentiation during pregnancy has not been reported. We present the case of a 25-year-old woman in the third trimester of pregnancy with a large intracranial tumor destructing the parietal calvaria and invasion of soft tissues. Histological examination revealed primary meningeal sarcoma with leiomyoblastic differentiation. A gross macroscopical resection of the tumor with removal of the infiltrated parietal calvaria was performed after delivery of a healthy baby through caesarean section. A mass on the head rapidly enlarging during pregnancy should be considered for a malignancy of intracranial origin. Early radiological exams as well as tumor resection followed by staging and multimodality treatment should be urgently performed.
Hong
Bujung
B
Department of Neurosurgery, Hannover Medical School, 30625 Hannover, Germany. hong.bujung@mh-hannover.de
Hermann
Elvis J
EJ
Hollwitz
Bettina
B
Klein
Rüdiger
R
Agaronjan
Armen
A
Krauss
Joachim K
JK
D000328:Adult; D001921:Brain / Q000473:pathology; D002585:Cesarean Section; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018230:Leiomyoma, Epithelioid / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000628:therapy; D011256:Pregnancy Outcome; D012509:Sarcoma / Q000150:complications* / Q000473:pathology / Q000628:therapy