title: Right ventricular function in patients with pulmonary embolism: early and late findings using Doppler tissue imaging.
abstract: BACKGROUND
  Assessments of right ventricular (RV) function using myocardial velocities in patients with pulmonary embolism (PE) may add vital information.
  
  
  METHODS
  Thirty-four patients with PE were studied in the acute stage and 3 months afterward. Tricuspid annular velocity was recorded using pulsed-wave Doppler tissue imaging.
  
  
  RESULTS
  At the time of diagnosis, tricuspid annular velocities were significantly decreased in patients compared with controls in systole (12.9 vs 14.8 cm/s, P < .05) and early diastole (11.9 vs 15.3 cm/s, P < .01) and normalized during follow-up. Decreases in tricuspid annular velocity were most pronounced in patients with increased RV pressure. The myocardial performance index was prolonged and pulmonary vascular resistance was higher in patients with increased RV pressure. The ratio of tricuspid flow to myocardial velocity (E/Em) was also increased compared with controls (4.5 vs 3.5, P < .05).
  
  
  CONCLUSIONS
  RV dysfunction in patients with PE was common in the acute phase but normalized within 3 months. Patients presenting with normal RV pressure had normal systolic but disturbed diastolic function.
authors.affiliation: Clinical Physiology Section, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. riikka.rydman@karolinska.se
authors.forename: Riikka
authors.initials: R
authors.lastname: Rydman
authors.forename: Flemming
authors.initials: F
authors.lastname: Larsen
authors.forename: Kenneth
authors.initials: K
authors.lastname: Caidahl
authors.forename: Mahbubul
authors.initials: M
authors.lastname: Alam
mesh_terms: D015150:Echocardiography, Doppler / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000150:complications* / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000209:etiology*