title: [Pathogens distribution and drug sensitivity of infantile dacryocystitis].
abstract: OBJECTIVE
  To investigate the pathogens and drug tolerance of infantile dacryocystitis in order to provide evidence for clinical drug use.
  
  
  METHODS
  230 cases of infant dacryocystitis (aged from 2 to 10 months, average 90 days) were analyzed for bacterial culture and drug sensitivity tests. These tests were performed following National Guide to Clinical Laboratory Procedures. Based on the results, analyzed the difference of pathogens in different year, the pathogens kind of dacryocystitis, main pathogens of infantile dacryocystitis, average isolation rate of pathogens and sensitive or resistance drug for pathogens.
  
  
  RESULTS
  Average detecting rate was 87.0% (200 cases). There is no difference for detecting rate in each year. The pathogens were predominantly gram-positive coccus 74.5% (149 cases), coagulase-negative staphylococcus 20.5% (41 cases) and staphylococcus aureus 11.0% (22 cases). Majority of these bacteria were sensitive to tobramycin, ciprofloxacin and levofloxacin. Gram-positive coccus was sensitive to tobramycin and levofloxacin. For gram-negative rod, tobramycin and chloromycetin were most sensitive drug. The sensitivity rates were 96.67% (29 cases). The resistant rates to erythromycin and penicillin were 66.67% (20 cases) and 80.00% (24 cases).
  
  
  CONCLUSIONS
  Coagulase-negative staphylococcus was the main pathogen of infantile dacryocystitis.
authors.affiliation: Department of Ophthalmology, Shenyang Children's Hospital, Shenyang 110032, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
authors.forename: Jiang-yue
authors.initials: JY
authors.lastname: Zhao
authors.forename: Qi-chang
authors.initials: QC
authors.lastname: Yan
authors.forename: Jin-song
authors.initials: JS
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Chen
authors.forename: Lin
authors.initials: L
authors.lastname: Lin
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003607:Dacryocystitis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000472:pathogenicity*; D006095:Gram-Positive Cocci / Q000187:drug effects / Q000472:pathogenicity*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents