Old age and outcome after primary angioplasty for acute myocardial infarction.
OBJECTIVE
To assess the influence of age as an independent factor determining the prognosis and outcome of patients with acute myocardial infarction (AMI) treated using primary percutaneous coronary intervention (PCI).


METHODS
A retrospective analysis from a dedicated database.


METHODS
A high-volume interventional cardiology center in the Netherlands.


METHODS
Four thousand nine hundred thirty-three consecutive patients with AMI.


METHODS
Baseline characteristics and clinical outcomes after 30 days and 1 year were compared according to age categorized in three groups: younger than 65, 65 to 74, and 75 and older. A more-detailed analysis was performed with six age groups, from younger than 40 to 80 and older.


RESULTS
Of the 4,933 consecutive patients with AMI treated with PCI between 1992 and 2004, 643 were aged 75 and older. Multivariate analysis revealed that patients aged 65 to 75 had a greater risk of 1-year mortality than those younger than 65 (adjusted odds ratio (AOR)=1.57, 95% confidence interval (CI)=1.15-2.16) and that those aged 75 and older had a greater risk of 1-year mortality than those younger than 65 (AOR=3.03, 95% CI=2.14-4.29).


CONCLUSIONS
In this retrospective analysis, older age was independently associated with greater mortality after PCI for AMI. Patients aged 65 and older had a higher risk of mortality than younger patients, and those aged 75 and older had the highest risk of mortality.
de Boer
Menko-Jan
MJ
Department of Cardiology, Isala Klinieken, Locatie Weezenlanden, Zwolle, the Netherlands. ereis@planet.nl
Ottervanger
Jan Paul
JP
Suryapranata
Harry
H
Hoorntje
Jan C A
JC
Dambrink
Jan-Henk E
JH
Gosselink
A T Marcel
AT
van't Hof
Arnoud W J
AW
Zijlstra
Felix
F
D000367:Age Factors; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome