title: Comparative study of potential endothelioprotectors and impaza in modeled nitric oxide deficiency.
abstract: Experimental NO deficiency induced by L-NAME injection led to the development of arterial hypertension, endothelial dysfunction, and cardiomyocyte hypertrophy and reduced blood content of nitrates and nitrites. Impaza, NO donors, activators of NO-synthase, antioxidants, and antihypertensive preparations produced endothelium-protective effect of different degree.
authors.affiliation: Kursk State Medical University, Federal Agency for Health Care and Social Development.
authors.forename: M V
authors.initials: MV
authors.lastname: Pokrovskii
authors.forename: V I
authors.initials: VI
authors.lastname: Kochkarov
authors.forename: T G
authors.initials: TG
authors.lastname: Pokrovskaya
authors.forename: E B
authors.initials: EB
authors.lastname: Artyushkova
authors.forename: E N
authors.initials: EN
authors.lastname: Pashin
authors.forename: L M
authors.initials: LM
authors.lastname: Danilenko
authors.forename: M V
authors.initials: MV
authors.lastname: Korokin
authors.forename: A S
authors.initials: AS
authors.lastname: Belous
authors.forename: L V
authors.initials: LV
authors.lastname: Korokina
authors.forename: V A
authors.initials: VA
authors.lastname: Malykhin
authors.forename: Ya I
authors.initials: YI
authors.lastname: Zaloznykh
authors.forename: M S
authors.initials: MS
authors.lastname: Brusnik
authors.forename: E S
authors.initials: ES
authors.lastname: Zhavbert
mesh_terms: D000818:Animals; D000906:Antibodies / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D004730:Endothelium, Vascular / Q000187:drug effects*; D006973:Hypertension / Q000139:chemically induced / Q000188:drug therapy; D008297:Male; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D009566:Nitrates / Q000378:metabolism; D009569:Nitric Oxide / Q000172:deficiency*; D020030:Nitric Oxide Donors / Q000627:therapeutic use; D009573:Nitrites / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D000077185:Resveratrol; D013267:Stilbenes / Q000627:therapeutic use
chemical_list: D000906:Antibodies; D000959:Antihypertensive Agents; D000975:Antioxidants; C534505:IMPAZA; D009566:Nitrates; D020030:Nitric Oxide Donors; D009573:Nitrites; D013267:Stilbenes; D009569:Nitric Oxide; D000077185:Resveratrol; D019331:NG-Nitroarginine Methyl Ester