title: Efficient kinetic resolution of racemic 3-nitro-2H-chromene derivatives catalyzed by Takemoto's organocatalyst.
abstract: Efficient kinetic resolution of racemic 3-nitro-2H-chromenes by bifunctional thiourea afforded optically active (R)-3-nitro-2H-chromene derivatives with moderate to good enantioselectivities, which simultaneously gave the multifunctional 3,4-diphenyl-3a-nitrobenzopyrano-[3,4-c]-pyrrolidine-1,1-dicarboxylate derivatives with four vicinal chiral carbon centers.
authors.affiliation: Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces, Department of Chemistry and Life Science, Zhejiang Normal University, Jinhua, 321004, China. xiejw@zjnu.cn
authors.forename: Jian-Wu
authors.initials: JW
authors.lastname: Xie
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Fan
authors.forename: Hong
authors.initials: H
authors.lastname: Su
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Li
authors.forename: Dong-Cheng
authors.initials: DC
authors.lastname: Xu
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007700:Kinetics; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013890:Thiourea / Q000031:analogs & derivatives / Q000737:chemistry*
chemical_list: C412074:5,7-dimethoxy-2-methyl-2H-benzopyran; D001578:Benzopyrans; D013890:Thiourea