Identification of a novel HLA-Cw*15 variant allele, Cw*1526.
A novel human leukocyte antigen (HLA)-Cw*15 variant allele was identified in a Chinese Han individual. It differs from the closest allele Cw*150201 by single nucleotide change at genomic nt 755 C>G (CDS nt 379 C>G, codon 103 CTG>GTG) in exon 3, which results in an amino acid change Leu103Val.
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Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China. riverch418@hotmail.com
Deng
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D000483:Alleles; D019943:Amino Acid Substitution; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D002681:China; D004247:DNA / Q000235:genetics; D017931:DNA Primers / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D012689:Sequence Homology, Nucleic Acid
D017931:DNA Primers; D015236:HLA-C Antigens; C446264:HLA-C*15 antigen; D004247:DNA