title: Understanding endorphins and their importance in pain management.
authors.affiliation: Department of Surgery, Division of Plastic Surgery, University of Hawai'i John A Burns School of Medicine, Honolulu, HI 96813, USA.
authors.forename: Adam S
authors.initials: AS
authors.lastname: Sprouse-Blum
authors.forename: Greg
authors.initials: G
authors.lastname: Smith
authors.forename: Daniel
authors.initials: D
authors.lastname: Sugai
authors.forename: F Don
authors.initials: FD
authors.lastname: Parsa
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D018377:Neurotransmitter Agents / Q000096:biosynthesis / Q000097:blood / Q000378:metabolism; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology; D017933:Peripheral Nervous System / Q000502:physiology; D010902:Pituitary Gland / Q000378:metabolism; D011957:Receptors, Opioid / Q000096:biosynthesis* / Q000097:blood / Q000378:metabolism; D001615:beta-Endorphin / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D018377:Neurotransmitter Agents; D011957:Receptors, Opioid; D001615:beta-Endorphin
references.citation: Endocrinology. 2004 Mar;145(3):1331-41
references.pmid: 14630714
references.citation: Dig Dis Sci. 2000 Sep;45(9):1703-13
references.pmid: 11052308
references.citation: J Dent Res. 1983 Nov;62(11):1170-3
references.pmid: 6580319
references.citation: J Clin Invest. 1988 Sep;82(3):767-74
references.pmid: 2843570
references.citation: Nat Genet. 2000 Nov;26(3):277-81
references.pmid: 11062465
references.citation: Nursing. 1981 Feb;11(2):50-3
references.pmid: 6905934
references.citation: Clin Pharmacol Ther. 1986 Aug;40(2):165-71
references.pmid: 3731680
references.citation: Pharmacotherapy. 1993 Jul-Aug;13(4):378-81
references.pmid: 8361864
references.citation: Mol Pharmacol. 1987 Nov;32(5):633-8
references.pmid: 2824980
references.citation: Trends Pharmacol Sci. 1992 May;13(5):177-84
references.pmid: 1604710
references.citation: Eur J Pharmacol. 2004 Oct 1;500(1-3):331-49
references.pmid: 15464044
references.citation: Aesthetic Plast Surg. 2009 Jan;33(1):98-103
references.pmid: 18712436
references.citation: Endocrinology. 1993 Nov;133(5):1921A-1921B
references.pmid: 8404637
references.citation: Brain Res. 1990 Jun 11;519(1-2):102-11
references.pmid: 2144463
references.citation: Neuroreport. 2003 Jan 20;14(1):1-7
references.pmid: 12544821
references.citation: J Pharmacol Exp Ther. 1996 Apr;277(1):551-8
references.pmid: 8613967
references.citation: Anesth Analg. 1985 Jul;64(7):677-80
references.pmid: 3160261
references.citation: Science. 1977 Sep 30;197(4311):1367-9
references.pmid: 197601
references.citation: Pain Manag Nurs. 2007 Sep;8(3):113-21
references.pmid: 17723928
references.citation: Lancet. 1998 Jun 20;351(9119):1828-9
references.pmid: 9652661
references.citation: Anesthesiology. 1982 Dec;57(6):468-72
references.pmid: 6293344
references.citation: Brain Res Mol Brain Res. 1996 Sep 5;41(1-2):140-7
references.pmid: 8883945
references.citation: N Engl J Med. 1995 Jun 22;332(25):1685-90
references.pmid: 7760870
references.citation: Anesth Analg. 2003 Feb;96(2):481-6, table of contents
references.pmid: 12538200
references.citation: Rheumatology (Oxford). 2006 Jun;45(6):765-70
references.pmid: 16449370