title: Carbohydrate alimentary overload laminitis.
abstract: In acute laminitis, the suspensory apparatus of the distal phalanx fails at the lamellar dermal/epidermal interface. A grading system for the histopathology of laminitis is based on the consistent pattern of histologic changes to the secondary epidermal lamellae, basal cells, and basement membrane that occur as carbohydrate-induced laminitis develops. The actual trigger factors of carbohydrate-induced laminitis remain unidentified.
authors.affiliation: School of Veterinary Science, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia. c.pollitt@uq.edu.au
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Pollitt
authors.forename: Michelle B
authors.initials: MB
authors.lastname: Visser
mesh_terms: D000824:Animal Nutritional Physiological Phenomena / Q000502:physiology*; D000818:Animals; D001485:Basement Membrane / Q000473:pathology / Q000648:ultrastructure; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000009:adverse effects* / Q000378:metabolism; D004817:Epidermis / Q000473:pathology / Q000648:ultrastructure; D005534:Foot Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D006724:Hoof and Claw / Q000473:pathology* / Q000648:ultrastructure; D006734:Horse Diseases / Q000209:etiology / Q000473:pathology*; D006736:Horses; D007150:Immunohistochemistry / Q000662:veterinary; D007249:Inflammation / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D012720:Severity of Illness Index
chemical_list: D004040:Dietary Carbohydrates