Morphofunctional analysis of development of nonthyroid disease syndrome in experimental endotoxicosis.
The development of the nonthyroid disease syndrome in acute endotoxicosis involves mechanisms related to polarization of the immune response by the Th1 type. Thyroid status of rats with pronounced and weak polarization of the immune response was evaluated. Morphofunctional changes in the thyroid gland in animals with the central and peripheral mechanisms of the development and regression of the nonthyroid disease syndrome were detected.
Yaglova
N V
NV
Institute of Human Morphology, the Russian Academy of Medical Sciences, Moscow, Russia. yaglova@mail.ru
D000818:Animals; D001424:Bacterial Infections / Q000150:complications / Q000276:immunology / Q000503:physiopathology; D016000:Cluster Analysis; D007107:Immune System / Q000276:immunology; D008070:Lipopolysaccharides / Q000008:administration & dosage / Q000276:immunology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013577:Syndrome; D018417:Th1 Cells / Q000276:immunology; D013959:Thyroid Diseases / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology / Q000503:physiopathology
D008070:Lipopolysaccharides