title: [Coronary CT angiography using prospective ECG triggering: high diagnostic accuracy with low radiation dose].
abstract: BACKGROUND
  The purpose of this study was to evaluate the diagnostic performance of coronary CT angiography (coronary CTA) using prospective ECG triggering (PT) for the detection of significant coronary artery stenosis compared to invasive coronary angiography (ICA).
  
  
  METHODS
  A total of 20 patients underwent coronary CTA with PT using a 128-slice CT scanner (Definition AS+, Siemens) and ICA. All coronary CTA studies were evaluated for significant coronary artery stenoses (>or=50% luminal narrowing) by 2 observers in consensus using the AHA-15-segment model. Findings in CTA were compared to those in ICA.
  
  
  RESULTS
  Coronary CTA using PT had 88% sensitivity in comparison to 100% with ICA, 95% to 88% specificity, 80% to 92% positive predictive value and 97% to 100% negative predictive value for diagnosing significant coronary artery stenosis on per segment per patient analysis, respectively. Mean effective radiation dose-equivalent of CTA was 2.6+/-1 mSv.
  
  
  CONCLUSIONS
  Coronary CTA using PT enables non-invasive diagnosis of significant coronary artery stenosis with high diagnostic accuracy in comparison to ICA and is associated with comparably low radiation exposure.
authors.affiliation: Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, Charleston, USA. Elisabeth.Arnoldi@med.uni-muenchen.de
authors.forename: E
authors.initials: E
authors.lastname: Arnoldi
authors.forename: I
authors.initials: I
authors.lastname: Ramos-Duran
authors.forename: J A
authors.initials: JA
authors.lastname: Abro
authors.forename: P L
authors.initials: PL
authors.lastname: Zwerner
authors.forename: K
authors.initials: K
authors.lastname: Nikolaou
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
authors.forename: P
authors.initials: P
authors.lastname: Costello
authors.forename: U J
authors.initials: UJ
authors.lastname: Schoepf
mesh_terms: D000368:Aged; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
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