title: Analysis of environmental endocrine disrupting activities using recombinant yeast assay in wastewater treatment plant effluents.
abstract: A battery of in vitro recombinant yeast bioassays was conducted to assess the estrogen receptor, androgen receptor, progesterone receptor and thyroid receptor ant/agonistic activities of effluents collected from Datansha wastewater treatment plant (WWTP), furthermore to evaluate the removal efficiencies of endocrine disrupting chemicals in the WWTP. The results showed that estrogenic, anti-androgenic, anti-progesteronic and anti-thyroidic activities were observed in influent. The removal efficiencies of these compounds were more than 80%, which suggested that the present wastewater treatment processes were good enough to remove most of all kinds of endocrine disruption chemicals.
authors.affiliation: College of Water Sciences, Beijing Normal University, 100875 Beijing, People's Republic of China. lijian@bnu.edu.cn
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Zijian
authors.initials: Z
authors.lastname: Wang
authors.forename: Mei
authors.initials: M
authors.lastname: Ma
authors.forename: Xianzhi
authors.initials: X
authors.lastname: Peng
mesh_terms: D001681:Biological Assay / Q000379:methods*; D002681:China; D052244:Endocrine Disruptors / Q000032:analysis / Q000633:toxicity*; D004784:Environmental Monitoring; D007220:Industrial Waste / Q000032:analysis*; D011987:Receptors, Steroid / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics; D014865:Waste Disposal, Fluid / Q000379:methods*; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*; D018508:Water Purification
chemical_list: D052244:Endocrine Disruptors; D007220:Industrial Waste; D011987:Receptors, Steroid; D014874:Water Pollutants, Chemical; D014867:Water