Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial.
BACKGROUND
If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS(R) gives an eightfold concentrate platelets of patients own blood. Injection of these platelets in the attachment of the fascia to the os calcis might induce a healing rate.


METHODS
A randomized controlled multi centre trial will be performed. The study population consists of 120 patients of 18 years and older. Patients with chronic plantar fasciitis will be allocated randomly to have a steroid injection or an autologous platelet concentrate injections. Data will be collected before the procedure, 4,8,12,26 weeks and 1 year after the procedure.The main outcome measures of this study are pain and function measured with questionnaires.


CONCLUSIONS
Recent literature show positive effects for the treatment of tendinosis with autologous platelet injections. The forthcoming trial will compare treatment for chronic plantar fasciitis with a steroid injection versus an autologous platelet injection. Our results will be published as soon as they become available.


BACKGROUND



BACKGROUND
http://www.clinicaltrials.gov NCT00758641.
Peerbooms
Joost C
JC
Department of Orthopaedics, Elisabeth Ziekenhuis Tilburg, The Netherlands.
van Laar
Wilbert
W
Faber
Frank
F
Schuller
Hans M
HM
van der Hoeven
Henk
H
Gosens
Taco
T
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage; D002985:Clinical Protocols; D002986:Clinical Trials as Topic / Q000379:methods; D004185:Disability Evaluation; D036981:Fasciitis, Plantar / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D009426:Netherlands; D017063:Outcome Assessment, Health Care / Q000379:methods; D010147:Pain Measurement / Q000379:methods; D017060:Patient Satisfaction; D017713:Platelet Transfusion / Q000379:methods*; D053657:Platelet-Rich Plasma / Q000502:physiology*; D011788:Quality of Life; D012107:Research Design; D011795:Surveys and Questionnaires; D014182:Transplantation, Autologous / Q000379:methods; D014945:Wound Healing / Q000502:physiology*; D055815:Young Adult
D000305:Adrenal Cortex Hormones; D000779:Anesthetics, Local
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