title: Sugar signalling and antioxidant network connections in plant cells.
abstract: Sugars play important roles as both nutrients and regulatory molecules throughout plant life. Sugar metabolism and signalling function in an intricate network with numerous hormones and reactive oxygen species (ROS) production, signalling and scavenging systems. Although hexokinase is well known to fulfil a crucial role in glucose sensing processes, a scenario is emerging in which the catalytic activity of mitochondria-associated hexokinase regulates glucose-6-phosphate and ROS levels, stimulating antioxidant defence mechanisms and the synthesis of phenolic compounds. As a new concept, it can be hypothesized that the synergistic interaction of sugars (or sugar-like compounds) and phenolic compounds forms part of an integrated redox system, quenching ROS and contributing to stress tolerance, especially in tissues or organelles with high soluble sugar concentrations.
authors.affiliation: Department of Agronomy, Plant Breeding and Biotechnology, Sari Agricultural Science and Natural Resources University, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Bolouri-Moghaddam
authors.forename: Katrien
authors.initials: K
authors.lastname: Le Roy
authors.forename: Li
authors.initials: L
authors.lastname: Xiang
authors.forename: Filip
authors.initials: F
authors.lastname: Rolland
authors.forename: Wim
authors.initials: W
authors.lastname: Van den Ende
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D006801:Humans; D010944:Plants / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D000975:Antioxidants; D017382:Reactive Oxygen Species