title: Successful treatment of aortic root dilatation in a patient with relapsing polychondritis.
abstract: Cardiovascular involvement occurring in 20-30% patients is the second most common cause of mortality in patients with relapsing polychondritis. Aortic insufficiency occurs as a result of aortic root dilatation rather than primary valvular involvement. We are reporting a patient of relapsing polychondritis with aortic root dilatation, in whom institution of early and aggressive therapy successfully prevented the progression of aortic insufficiency.
authors.affiliation: Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, 160012 Chandigarh, India. amansharma74@yahoo.com
authors.forename: Aman
authors.initials: A
authors.lastname: Sharma
authors.forename: Tarun
authors.initials: T
authors.lastname: Mittal
authors.forename: Susheel
authors.initials: S
authors.lastname: Kumar
authors.forename: Arjun Datt
authors.initials: AD
authors.lastname: Law
authors.forename: Ajay
authors.initials: A
authors.lastname: Wanchu
authors.forename: Rajiv
authors.initials: R
authors.lastname: Mahajan
authors.forename: Pradeep
authors.initials: P
authors.lastname: Bambery
authors.forename: Surjit
authors.initials: S
authors.lastname: Singh
mesh_terms: D001011:Aorta / Q000187:drug effects* / Q000473:pathology; D001018:Aortic Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000473:pathology / Q000517:prevention & control; D001379:Azathioprine / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004108:Dilatation, Pathologic / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D057915:Drug Substitution; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011081:Polychondritis, Relapsing / Q000150:complications / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011239:Prednisolone; D009173:Mycophenolic Acid; D001379:Azathioprine; D008775:Methylprednisolone
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