Identification of two novel HLA-B alleles in the Brazilian population: B*4509 and B*5212.
Human leucocyte antigen (HLA)-B*4509 differs from the closest HLA-B*4502 by three nucleotides that lead to changes of Tyr113His, Asn114Asp and Phe116Ser. HLA-B*5212 differs from HLA-B*520101 by a single nucleotide substitution, leading to a change of Asn114Asp.
Veiga
T R
TR
Immunogenetics Division, Department of Pediatrics, Universidade Federal de São Paulo (UNIFESP-EPM), São Paulo, Brazil. thiveiga@igen.epm.br
Rampim
G F
GF
de Lima
M Gerbase
MG
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D001938:Brazil; D004247:DNA / Q000235:genetics; D017931:DNA Primers / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D012689:Sequence Homology, Nucleic Acid
D017931:DNA Primers; D015235:HLA-B Antigens; D004247:DNA