title: Apolipoprotein B/A-I ratio related to visceral but not to subcutaneous adipose tissue in elderly Swedes.
abstract: OBJECTIVE
  To investigate whether the amount of visceral (VAT) or subcutaneous adipose tissue (SAT) independently of the other can determine the apolipoprotein (apo)B/A-I ratio.
  
  
  METHODS
  VAT and SAT areas were assessed using magnetic resonance imaging in 247 randomly selected 70-year-old men and women who did not use lipid-lowering drugs. Their adipose tissue areas were compared to their apoB and apo A-I levels and to their apoB/A-I ratios.
  
  
  RESULTS
  The VAT area and the gender were significantly related to the apoB/A-I ratio whereas the SAT area was not. There was a positive relationship between the VAT area and the apoB/A-I ratio.
  
  
  CONCLUSIONS
  A positive relationship was established between the amount of VAT and the apoB/A-I ratio, whereas there was no relationship between the amount of SAT and the apoB/A-I ratio. This observation supports the notion that VAT is metabolically active.
authors.affiliation: Department of Radiology, Uppsala University Hospital, 75185 Uppsala, Sweden. Charlotte.Ebeling Barbier@radiol.uu.se
authors.forename: Charlotte Ebeling
authors.initials: CE
authors.lastname: Barbier
authors.forename: Lars
authors.initials: L
authors.lastname: Lind
authors.forename: Håkan
authors.initials: H
authors.lastname: Ahlström
authors.forename: Anders
authors.initials: A
authors.lastname: Larsson
authors.forename: Lars
authors.initials: L
authors.lastname: Johansson
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000368:Aged; D016632:Apolipoprotein A-I / Q000378:metabolism*; D001055:Apolipoproteins B / Q000378:metabolism*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011897:Random Allocation; D012044:Regression Analysis; D012737:Sex Factors; D050151:Subcutaneous Fat / Q000473:pathology*; D013548:Sweden
chemical_list: D016632:Apolipoprotein A-I; D001055:Apolipoproteins B