title: [Pterygium. Etiology, clinical aspects and novel adjuvant therapies].
abstract: Pterygium is a common UV-induced degeneration of the limbal conjunctiva. Indications for surgery include loss of visual acuity, increasing astigmatism, impending invasion of the optical axis and ocular surface discomfort. Measures to reduce the risk of recurrence include 1. an optimal surgical strategy (intra-operative use of antimetabolites and free conjunctival graft), 2. postoperative topical therapy with steroids and lubricants free of preservatives and 3. long-term UV protection. Novel anti-angiogenic treatment approaches for prevention of recurrence of pterygium are discussed.
authors.affiliation: Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Erlangen.
authors.forename: L M
authors.initials: LM
authors.lastname: Heindl
authors.forename: C
authors.initials: C
authors.lastname: Cursiefen
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000477:Alkylating Agents / Q000008:administration & dosage; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000473:pathology / Q000528:radiation effects / Q000637:transplantation; D003937:Diagnosis, Differential; D005123:Eye / Q000528:radiation effects*; D005135:Eye Protective Devices; D006801:Humans; D016685:Mitomycin / Q000008:administration & dosage; D011625:Pterygium / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D011832:Radiation Injuries / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D055502:Secondary Prevention; D014466:Ultraviolet Rays / Q000009:adverse effects*
chemical_list: D000305:Adrenal Cortex Hormones; D000477:Alkylating Agents; D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D016685:Mitomycin
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