Incidence and risk factors for the development of anemia following gastric bypass surgery.
OBJECTIVE
To evaluate the incidence and risk factors for the development of anemia after Roux-en-Y gastric bypass (RYGB).


METHODS
A retrospective analysis of patients undergoing RYGB from January 2003 to November 2007 was performed. All patients had a preoperative body mass index > 40 kg/m(2). A total of 206 patients were evaluated. All patients were given daily supplements of ferrous sulfate tablets for 2 wk following their operation. Hematological and metabolic indices were routinely evaluated following surgery. Patients were followed for a minimum of 86 wk.


RESULTS
There were 41 males and 165 females with an average age of 40.8 years. 21 patients (10.2%) developed post-operative anemia and 185 patients (89.8%) did not. Anemia was due to iron deficiency in all cases. The groups had similar demographics, surgical procedure and co-morbidities. Menstruation (P = 0.02) and peptic ulcer disease (P = 0.01) were risk factors for the development of post-operative anemia.


CONCLUSIONS
Iron deficiency anemia is frequent. RYGB surgery compounds occult blood loss. Increased ferrous sulfate supplementation may prevent iron depletion in populations at increased risk.
Avgerinos
Dimitrios V
DV
Department of Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 10003, United States.
Llaguna
Omar H
OH
Seigerman
Matthew
M
Lefkowitz
Amanda J
AJ
Leitman
I Michael
IM
D000328:Adult; D000740:Anemia / Q000175:diagnosis / Q000209:etiology*; D015992:Body Mass Index; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000601:surgery; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
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