title: [Determination content of baicalin in Yinhuang granules from different pharmaceutical factories by near-infrared spectroscopy].
abstract: OBJECTIVE
  To determine the content of baicalin in Yinhuang granules fastly from different pharmaceutical factories with near-infrared spectroscopy.
  
  
  METHODS
  Near-infrared diffuse reflectance spectroscopy technology was used to collect NIR spectra of Yinhuang granules. With HPLC anilysis values as reference, the fast determination method of baicalin was established with partial least squares (PLS).
  
  
  RESULTS
  The correlation coefficients (R2), the root-mean-square error of cross-validation and the root-mean-square error of calibration (RMSEC) of the calibration model for baicalin were 0.9982, 0.1899 and 0.0514, respectively; the root-mean-square error of prediction (RMSEP) and the average rate of recovery were 0.0802 and 104.27%.
  
  
  CONCLUSIONS
  The method is accurate, fast and simple, and can be applied for the fast determination of large quantities of numbers of samples.
authors.affiliation: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China. white_yan@hotmail.com
authors.forename: Yan
authors.initials: Y
authors.lastname: Bai
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Xing
authors.initials: X
authors.lastname: Wang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005419:Flavonoids / Q000032:analysis*; D011786:Quality Control; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C038044:baicalin