Phenanthrene derivatives from the stems and leaves of Dioscorea nipponica Makino.
From the CHCl(3)-soluble portion of the 70% EtOH extract of the stems and leaves of Dioscorea nipponica Makino, two new phenanthrenes, 7-hydroxy-2,3,5-trimethoxy-9,10-dihydrophenanthrene (1) and 2,2',7,7'-tetrahydroxy-4,4',6,6'-tetramethoxy-1,1'-biphenanthrenes (2), as well as three known phenanthrenes, 6-methoxycoelonin (3), 4,7-dihydroxy-2,3,6-trimethoxyphenanthrene (4), and 3,7-dihydroxy-2,4,6-trimethoxyphenanthrene (5), were isolated. The structures were determined by means of HR-MS, (1)H NMR, (13)C NMR, and HMBC experiments.
Lu
Dan
D
Institute of Frontier Medical Science, Jilin University, Changchun, China.
Liu
Jin-Ping
JP
Li
Hai-Jun
HJ
Li
Ping-Ya
PY
D027742:Dioscorea / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
C549184:2,2',7,7'-tetrahydroxy-4,4',6,6'-tetramethoxy-1,1'-biphenanthrene; C549183:7-hydroxy-2,3,5-trimethoxy-9,10-dihydrophenanthrene; D004365:Drugs, Chinese Herbal; D010616:Phenanthrenes