title: Six-component reactions for the stereoselective synthesis of 3-arylidene-2-oxindoles via sequential one-pot Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition.
abstract: An efficient palladium-catalyzed protocol for the synthesis of 3-arylidene-2-oxindoles has been developed. In this approach, a sequential one-pot six-component reaction via Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition was used for the synthesis of the desired skeleton.
authors.affiliation: Peptide Chemistry Research Group, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran, Iran.
authors.forename: Morteza
authors.initials: M
authors.lastname: Bararjanian
authors.forename: Saeed
authors.initials: S
authors.lastname: Balalaie
authors.forename: Frank
authors.initials: F
authors.lastname: Rominger
authors.forename: Barahman
authors.initials: B
authors.lastname: Movassagh
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Bijanzadeh
mesh_terms: D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*; D015394:Molecular Structure; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D010165:Palladium