title: Solid focal liver lesions: dynamic and late enhancement patterns with the dual phase contrast agent gadobenate dimeglumine.
abstract: BACKGROUND
  The purpose of this paper is to illustrate contrast enhancement patterns of solid focal liver lesions on dynamic and late phase imaging with gadobenate dimeglumine (Gd-BOPTA).
  
  
  RESULTS
  Unenhanced T2- and T1-weighted, dynamic T1-weighted (arterial, portal-venous, and equilibrium) and late phase (1-3 h) Gd-BOPTA-enhanced MR imaging of different focal liver lesions (nodular regenerative hyperplasia, hepatic adenoma, liver adenomatosis, hepatocellular carcinoma, peripheral cholangiocarcinoma, hypervascular metastases, and hypovascular metastases) are shown. Dynamic imaging was performed using GRE T1-w sequences after the bolus injection of 0.1 mmol/kg Gd-BOPTA; late-phase imaging was obtained at 1-3 h after contrast injection.
  
  
  CONCLUSIONS
  Dynamic imaging with Gd-BOPTA provides the same information as with conventional gadolinium-based extracellular contrast agents, while late-phase imaging gives additional information for lesion identification and characterization.
authors.affiliation: Department of Radiology, University of Brescia, Brescia, Italy. lgrazioli@yahoo.com
authors.forename: Luigi
authors.initials: L
authors.lastname: Grazioli
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Bondioni
authors.forename: Niccolò
authors.initials: N
authors.lastname: Faccioli
authors.forename: Sebastiana
authors.initials: S
authors.lastname: Gambarini
authors.forename: Rita
authors.initials: R
authors.lastname: Tinti
authors.forename: Günther
authors.initials: G
authors.lastname: Schneider
authors.forename: Miles
authors.initials: M
authors.lastname: Kirchin
mesh_terms: D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008107:Liver Diseases / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008536:Meglumine / Q000031:analogs & derivatives*; D009942:Organometallic Compounds
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine
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