title: Direct evaluation of cellular internalization rates using chromogenic disulfides.
abstract: A practical assay, which exploits the maintenance of the cytoplasmic redox balance in live cells, has been developed to report in real time on relative cellular internalization rates of molecules derivatized as chromogenic disulfides.
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN 47909, USA.
authors.forename: Megan E
authors.initials: ME
authors.lastname: Bucks
authors.forename: Sergey N
authors.initials: SN
authors.lastname: Savinov
mesh_terms: D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism*; D002863:Chromogenic Compounds / Q000737:chemistry / Q000378:metabolism*; D004220:Disulfides / Q000737:chemistry / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism*; D008954:Models, Biological; D015394:Molecular Structure
chemical_list: D002863:Chromogenic Compounds; D004220:Disulfides