title: Rhazes, a genius physician in diagnosis and treatment of kidney calculi in medical history.
abstract: Abu Bakr Mohammad Ibn Zakariya Razi, known in the west as Rhazes (865 to 925 AD), was born in the ancient city of Rayy, near Tehran, Iran. He was a renowned physician in medical history and not only followed Hippocrates and Galen, but also greatly extended the analytical approach of his predecessors. Based on the existing documents, he was known as the most distinguished character in the world of medicine up to the 17th century. A great number of innovations and pioneering works in the medical science have been recorded in the name of Rhazes. His fundamental works in urology as part of his research in the realm of medicine have remained unknown. Pathophysiology of the urinary tract, venereal diseases, and kidney and bladder calculi are among his main interests in this field. He also purposed and developed methods for diagnosis and treatment of kidney calculi for the first time in medical history. He also presented a very exact and precise description of neuropathic bladder followed by vertebral fracture. He advanced urine analysis and studied function and diseases of the kidneys. Rhazes recommendations for the prevention of calculi are quite scientific and practical and in accordance with current recommendations to avoid hypercalciuria and increased saturation of urine. Rhazes was not only one of the most important Persian physician-philosophers of his era, but for centuries, his writings became fundamental teaching texts in European medical schools. Some important aspects of his contributions to medicine are reviewed.
authors.affiliation: Department of Physiology, Arak University of Medical Sciences, Arak, Iran. ashtiyani@sums.ac.ir
authors.forename: Saeed
authors.initials: S
authors.lastname: Changizi Ashtiyani
authors.forename: Ali
authors.initials: A
authors.lastname: Cyrus
mesh_terms: D049690:History, Ancient; D006801:Humans; D007492:Iran; D007669:Kidney Calculi / Q000175:diagnosis / Q000266:history* / Q000601:surgery; D016482:Urinalysis / Q000266:history; D013520:Urologic Surgical Procedures / Q000266:history* / Q000379:methods; D014572:Urology / Q000266:history*