title: Photoacoustic correlation spectroscopy and its application to low-speed flow measurement.
abstract: A photoacoustic correlation technique, inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS)-was tested for the first time, to our knowledge, to demonstrate the feasibility of low-speed flow measurement based on photoacoustic signal detection. A pulsed laser was used to probe the flow of light-absorbing beads. A photoacoustic correlation system of 0.8 s temporal resolution was built and flow speeds ranging from 249 to 14.9 microm/s with corresponding flow times from 4.42 to 74.1 s were measured. The experiment serves as a proof of concept for photoacoustic correlation spectroscopy, which may have many potential applications similar to the FCS.
authors.affiliation: Department of Electrical Engineering and Computer Science, University of Michigan,Ann Arbor, Michigan 48109, USA.
authors.forename: Sung-Liang
authors.initials: SL
authors.lastname: Chen
authors.forename: Tao
authors.initials: T
authors.lastname: Ling
authors.forename: Sheng-Wen
authors.initials: SW
authors.lastname: Huang
authors.forename: Hyoung
authors.initials: H
authors.lastname: Won Baac
authors.forename: L Jay
authors.initials: LJ
authors.lastname: Guo
mesh_terms: D001775:Blood Circulation; D002138:Calibration; D004912:Erythrocytes / Q000502:physiology; D005240:Feasibility Studies; D006801:Humans; D008853:Microscopy; D013050:Spectrometry, Fluorescence; D013057:Spectrum Analysis / Q000379:methods*
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