title: Characterization of the correlation between ages at entry into breast and pubic hair development.
abstract: OBJECTIVE
  The timing of breast and pubic hair development in girls are related, but the degree of correlation has not been well characterized. Periodic observations also are complicated by interval censoring.
  
  
  METHODS
  Data used were from the Avon Longitudinal Study of Parents and Children. Mean age at entry into breast and pubic hair development was determined by the use of parametric survival analysis. The bivariate normal cumulative distribution function was evaluated over the region containing the paired event times; the likelihood was maximized with respect to the correlation coefficient rho.
  
  
  RESULTS
  Among 3938 participants, estimated mean ages at entry into Tanner stage 2 for breast and pubic hair development were 10.19 and 10.95, respectively. The likelihood was maximized at rho = 0.503 to 0.506. This value remained relatively constant among subgroups, although some heterogeneity was observed by maternal and child body mass index and birth order.
  
  
  CONCLUSIONS
  The timing of breast and of pubic hair development is moderately correlated and remain so when it is stratified by characteristics associated with puberty.
authors.affiliation: Epidemiology Department, Emory University, Atlanta, GA 30322, USA. klyorita@gmail.com
authors.forename: Krista Yorita
authors.initials: KY
authors.lastname: Christensen
authors.forename: Mildred
authors.initials: M
authors.lastname: Maisonet
authors.forename: Carol
authors.initials: C
authors.lastname: Rubin
authors.forename: W Dana
authors.initials: WD
authors.lastname: Flanders
authors.forename: Carolyn
authors.initials: C
authors.lastname: Drews-Botsch
authors.forename: Celia
authors.initials: C
authors.lastname: Dominguez
authors.forename: Michael A
authors.initials: MA
authors.lastname: McGeehin
authors.forename: Michele
authors.initials: M
authors.lastname: Marcus
mesh_terms: D000293:Adolescent; D000367:Age Factors; D015992:Body Mass Index; D002648:Child; D005260:Female; D006197:Hair / Q000254:growth & development*; D006801:Humans; D016013:Likelihood Functions; D042361:Mammary Glands, Human / Q000254:growth & development*; D015999:Multivariate Analysis; D011627:Puberty; D013223:Statistics as Topic; D016019:Survival Analysis
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