title: Von Willebrand factor expression in endometrial endothelial cells in women with menorrhagia.
abstract: This prospective study assessed von Willebrand factor (VWF) expression in the endometrium using immunohistochemical staining in women with menorrhagia with or without von Willebrand disease (VWD) compared with a control group of women with normal menstrual loss. Endometrial VWF expression is significantly lower in women with VWD, which may play a local underlying role in pathogenesis of menorrhagia in these women.
authors.affiliation: Department of Obstetrics and Gynaecology, Royal Free Hospital, Hampstead, London, United Kingdom.
authors.forename: Umber
authors.initials: U
authors.lastname: Agarwal
authors.forename: Soha
authors.initials: S
authors.lastname: El Sheikh
authors.forename: Ashwini
authors.initials: A
authors.lastname: Kulkarni
authors.forename: Donna
authors.initials: D
authors.lastname: Baff
authors.forename: Rezan A
authors.initials: RA
authors.lastname: Kadir
mesh_terms: D000328:Adult; D001706:Biopsy; D016022:Case-Control Studies; D004717:Endometrium / Q000378:metabolism* / Q000473:pathology; D042783:Endothelial Cells / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008595:Menorrhagia / Q000378:metabolism* / Q000473:pathology; D008597:Menstrual Cycle / Q000378:metabolism; D008875:Middle Aged; D014841:von Willebrand Factor / Q000378:metabolism*
chemical_list: D014841:von Willebrand Factor