title: Dynamic constructs for spinal fusion: an evidence-based review.
abstract: Dynamic stabilization of the spine has applications in cervical and lumbar degenerative disease and in thoracolumbar trauma. There is little evidence to support the use of dynamic cervical plates rather than rigid anterior cervical fixation. Evidence to support the use of dynamic constructs for fusion in the lumbar spine is also limited. Fusion rates, implant loosening, and failure are significant concerns that limit the adoption of current devices. This article provides a synopsis of the literature on human subjects. There is a need for high-quality evidence for interventions for spinal pathology. An evidence-based approach to the management of spinal disorders will require ongoing assessment of clinical outcomes and comparison of effectiveness between alternatives.
authors.affiliation: Department of Orthopaedic Surgery, University of California, 500 Parnassus Avenue, MU 320-W, San Francisco, CA 94110, USA. kellym@orthosurg.ucsf.edu
authors.forename: Michael P
authors.initials: MP
authors.lastname: Kelly
authors.forename: James M
authors.initials: JM
authors.lastname: Mok
authors.forename: Sigurd
authors.initials: S
authors.lastname: Berven
mesh_terms: D001577:Benzophenones; D001672:Biocompatible Materials / Q000627:therapeutic use; D001860:Bone Plates; D004867:Equipment Design; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000601:surgery*; D007659:Ketones / Q000627:therapeutic use; D008159:Lumbar Vertebrae; D009984:Orthopedic Fixation Devices; D011092:Polyethylene Glycols / Q000627:therapeutic use; D011108:Polymers; D011475:Prosthesis Failure; D013123:Spinal Fusion / Q000295:instrumentation
chemical_list: D001577:Benzophenones; D001672:Biocompatible Materials; D007659:Ketones; D011108:Polymers; C063834:polyetheretherketone; D011092:Polyethylene Glycols