title: Terpenes and flavonoids from an Egyptian collection of Cleome droserifolia.
abstract: Four new sesquiterpene derivatives have been isolated from the aerial parts of Cleome droserifolia. Their structures were established as 6-di(7-hydroxy, 1, 5-epoxy germacrane) (2), 4(15)-guaiane-6-ol (3), 7alpha-germacra-1(10), 4(15)-diene-5beta, 6alpha-diol (4) and 4,7,8-eudesma-triol (5). In addition, a new dolabellane diterpene derivative with the naturally rare peroxy function was identified as methyl ester of 2,18-O-diacetyl-16-O-(3-hydroxy-3-methylglutaryl)-7-hydroperoxydolabella-3,8(17)diene-2,16,18 triol (7). Two known flavonoid derivatives, pinocembrin (6) and quercetin-3-glucoside,7-rhamnoside (1) were isolated from the same source. Structures were established by spectroscopic data.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria 21215, Egypt.
authors.forename: Mohamed I
authors.initials: MI
authors.lastname: Aboushoer
authors.forename: Hoda M
authors.initials: HM
authors.lastname: Fathy
authors.forename: Maged S
authors.initials: MS
authors.lastname: Abdel-Kader
authors.forename: Gilles
authors.initials: G
authors.lastname: Goetz
authors.forename: Abdallah A
authors.initials: AA
authors.lastname: Omar
mesh_terms: D031485:Cleome / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D012717:Sesquiterpenes / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D005419:Flavonoids; D012717:Sesquiterpenes; D013729:Terpenes; C115566:dolabellane