Dengue virus surveillance for early warning, Singapore.
In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement within DENV-2 cosmopolitan genotype, which accompanied the predominant serotype switch, and cocirculation of multiple genotypes of DENV-3.
Lee
Kim Sung
KS
Environmental Health Institute, Singapore .
Lai
Yee Ling
YL
Lo
Sharon
S
Barkham
Timothy
T
Aw
Pauline
P
Ooi
Peng Lim
PL
Tai
Ji Choong
JC
Hibberd
Martin
M
Johansson
Patrik
P
Khoo
Seow Poh
SP
Ng
Lee Ching
LC
D000330:Aedes / Q000821:virology; D000818:Animals; D003715:Dengue / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D004196:Disease Outbreaks; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008969:Molecular Sequence Data; D009032:Mosquito Control; D010802:Phylogeny; D011159:Population Surveillance; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics; D017422:Sequence Analysis, DNA; D012703:Serotyping; D012846:Singapore / Q000453:epidemiology; D014759:Viral Envelope Proteins / Q000032:analysis / Q000235:genetics
D012367:RNA, Viral; D014759:Viral Envelope Proteins
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