Subcutaneous beta2-microglobulin amyloid shoulder nodulesin a long-term hemodialysis patient.
beta2-Microglobulin accumulation with resultant tumor formation is a known albeit rare complication of long-term hemodialysis. Although these tumors may occur in various locations, subcutaneous shoulder nodules are very infrequent. We report a patient with end-stage kidney failure who had been on hemodialysis for 16 years and noted left shoulder nodules after initiation of hemodialysis; these nodules had slowly grown larger. Biopsy of one of these nodules revealed beta2-microglobulin amyloidosis by histopathology, Congo red stain, electron microscopy, and immunohistochemistry.
Mendoza
Paul D
PD
Department of Internal Medicine (Mendoza), Division of Nephrology (Fenves), Department of Pathology (Punar), and Department of Oncology (Stone), Baylor University Medical Center, Dallas, Texas.
Fenves
Andrew Z
AZ
Punar
Metin
M
Stone
Marvin J
MJ
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