Preeclampsia and adiponectin in cord blood.
OBJECTIVE
To compare cord blood concentrations of total adiponectin in the offspring of pregnancies with and without preeclampsia.


METHODS
Using a Luminex analyzer, cord blood adiponectin was measured in 182 singleton pregnancies with preeclampsia and compared to adiponectin measured in 511 singleton pregnancies without preeclampsia.


RESULTS
Adiponectin levels in cord blood increased with increasing gestational age, but overall, crude levels were similar in pregnancies with and without preeclampsia. However, in pregnancies with early delivery (weeks 32-36), and in pregnancies with delivery after spontaneous contractions, adiponectin levels were higher in the preeclampsia group.


CONCLUSIONS
In preterm pregnancies and in pregnancies with spontaneous contractions, adiponectin levels in cord blood were higher in the preeclampsia group than in pregnancies without preeclampsia, maybe reflecting the need to optimize energy in preeclampsia.
Ogland
Bjorn
B
Department of Pediatrics and the Central Laboratory, Stvanger University Hospital, Stavanger Norway. bogland@online.no
Romundstad
Pål R
PR
Vefring
Hege
H
Forman
Michele R
MR
Nilsen
Stein Tore
ST
Vatten
Lars J
LJ
D052242:Adiponectin / Q000097:blood*; D000328:Adult; D001724:Birth Weight; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009664:Norway; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy
D052242:Adiponectin
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