[Age- and sex-related differences of neuroendocrine center reactions in the hypothalamus on preparation thymalin and alpha-tocopherol acetate].
In experiment the action of Thymalin, alpha-tocopherol and stress on the centers of hypothalamus related to the regulation of the gonadotropic function has been investigated and the age-specific features of such influence as well. The results of experiments indicate the presence of neuron's reaction of the rostra preoptical area and arcuate nucleus for experimental influences. As a stress exposure and alpha-tocopherol injection to the young animals a reduction of neuron's kernels of the arcuate nucleus was observed, a sexual distinction wasn't revealed in the process. The response age-specific feature for alpha-tocopherol injection of the nucleus neuron's rostra preoptical and arcuate area of the hypothalamus of white rats is a reduction in a degree of response. Thymalin reduces a threshold of sensitivity of the neuron's arcuate center to action of stress.
Kozak
M V
MV
Teplyĭ
D L
DL
D000375:Aging / Q000187:drug effects / Q000473:pathology* / Q000523:psychology; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure; D005260:Female; D007031:Hypothalamus / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure; D009490:Neurosecretory Systems / Q000187:drug effects* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D012727:Sex Characteristics; D013315:Stress, Psychological / Q000473:pathology*; D013951:Thymus Hormones / Q000494:pharmacology*; D024502:alpha-Tocopherol / Q000494:pharmacology*
D013951:Thymus Hormones; C032805:thymalin; D024502:alpha-Tocopherol