title: Prevalence of metabolic syndrome in patients with intermittent claudication and its correlation with the segment of arterial obstruction.
abstract: The metabolic syndrome (MetS) is associated with increased cardiovascular morbidity and mortality. Intermittent claudication reflects the presence of peripheral arterial disease (PAD). The aim of this study is to determine the prevalence of the MetS in claudicants and its correlation with age, gender, localization of arterial obstruction, and symptomatic coronary disease. Patients (n = 170) with intermittent claudication were studied. The mean age was 65 years (33-89). Metabolic syndrome was diagnosed in 98 patients (57.6%). The mean age of patients with MetS was 63.5 years compared with 67.0 years for patients without MetS (P = .027). Considering patients aged ≥65 years, MetS was present in 46 (48.9%) individuals and in 52 (68.4%) patients younger than 65 years (P = .011). Metabolic syndrome must be actively searched for in claudicant patients.
authors.affiliation: Vascular and Endovascular Surgery Division, São Paulo University Medical School, São Paulo, Brazil. aezerati@uol.com.br
authors.forename: Antonio Eduardo
authors.initials: AE
authors.lastname: Zerati
authors.forename: Nelson
authors.initials: N
authors.lastname: Wolosker
authors.forename: Ruben Miguel
authors.initials: RM
authors.lastname: Ayzin Rosoky
authors.forename: Glauco
authors.initials: G
authors.lastname: Fernandes Saes
authors.forename: Luciana
authors.initials: L
authors.lastname: Ragazzo
authors.forename: Pedro
authors.initials: P
authors.lastname: Puech-Leão
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000150:complications* / Q000473:pathology; D007866:Leg / Q000098:blood supply*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000473:pathology; D049629:Waist-Hip Ratio