[Calcium polystyrene sulfonate induced colonic necrosis in patient with chronic kidney disease].
A 63-year-old woman was admitted due to right upper quadrant abdominal pain. She was going through hemodialysis due to end stage renal disease and taking calcium polystyrene sulfonate orally and rectally due to hyperkalemia. Colonoscopy showed a circular ulcerative mass on the proximal ascending colon. Biopsy specimen from the mass showed inflammation and necrotic debris. It also revealed basophilic angulated crystals which were adherent to the ulcer bed and normal mucosa. These crystals were morphologically consistent with calcium polystyrene sulfonate. She was diagnosed with calcium polystyrene phosphate induced colonic necrosis and improved with conservative treatment.
Lee
Sung Hoa
SH
Departments of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
Kim
Sung Jung
SJ
Kim
Go Eun
GE
Lee
Woo Jin
WJ
Hong
Won Ki
WK
Baik
Gwang Ho
GH
Choi
Young Hee
YH
Kim
Dong Joon
DJ
D003108:Colonic Diseases / Q000139:chemically induced / Q000150:complications / Q000473:pathology*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D009336:Necrosis; D011137:Polystyrenes / Q000009:adverse effects*
D011137:Polystyrenes; C003321:polystyrene sulfonic acid