Multihospital outbreak of Clostridium difficile infection, Cleveland, Ohio, USA.
To determine whether a multihospital Clostridium difficile outbreak was associated with epidemic strains and whether use of particular fluoroquinolones was associated with increased infection rates, we cultured feces from C. difficile-infected patients. Use of fluoroquionolones with enhanced antianaerobic activity was not associated with increased infection rates.
Jump
Robin L P
RL
University Hospitals of Cleveland, Cleveland, Ohio, USA.
Riggs
Michelle M
MM
Sethi
Ajay K
AK
Pultz
Michael J
MJ
Ellis-Reid
Tracie
T
Riebel
William
W
Gerding
Dale N
DN
Salata
Robert A
RA
Donskey
Curtis J
CJ
D000890:Anti-Infective Agents / Q000627:therapeutic use; D001372:Aza Compounds / Q000627:therapeutic use; D016360:Clostridioides difficile / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D024841:Fluoroquinolones / Q000627:therapeutic use; D000077734:Gatifloxacin; D005798:Genes, Bacterial; D006761:Hospitals; D006801:Humans; D000077266:Moxifloxacin; D009820:Ohio / Q000453:epidemiology; D011804:Quinolines / Q000627:therapeutic use
D000890:Anti-Infective Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D000077734:Gatifloxacin; D000077266:Moxifloxacin
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