title: Facile and efficient synthesis of functionalized iminothiopyran and isothiochromen via one-pot multicomponent reactions.
abstract: An efficient synthesis of 6H-6-iminothiopyran-2,3-dicarboxylate and 1H-isothiochromene-3,4-dicarboxylate derivatives via one-pot reactions between acetylenic esters, aryl isothiocyanates and enaminones in dichloromethane at room temperature is described. The mild reaction condition, high yields and the new products are advantages of our method.
authors.affiliation: Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
authors.forename: Hosein
authors.initials: H
authors.lastname: Hamadi
authors.forename: Mehdi
authors.initials: M
authors.lastname: Khoobi
authors.forename: Zinatossadat
authors.initials: Z
authors.lastname: Hossaini
authors.forename: Abbas
authors.initials: A
authors.lastname: Shafiee
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D006573:Heterocyclic Compounds, 1-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
chemical_list: D001578:Benzopyrans; D019086:Bridged Bicyclo Compounds, Heterocyclic; D006573:Heterocyclic Compounds, 1-Ring; D011714:Pyrans
references.citation: J Am Chem Soc. 2006 Aug 16;128(32):10354-5
references.pmid: 16895386
references.citation: Acc Chem Res. 2003 Dec;36(12):899-907
references.pmid: 14674781
references.citation: Angew Chem Int Ed Engl. 2000 Sep 15;39(18):3168-3210
references.pmid: 11028061
references.citation: J Am Chem Soc. 2005 Jan 19;127(2):605-13
references.pmid: 15643884
references.citation: Bioorg Med Chem Lett. 2002 Nov 4;12(21):3171-4
references.pmid: 12372526
references.citation: J Med Chem. 2000 Jul 27;43(15):2871-82
references.pmid: 10956195
references.citation: J Med Chem. 2002 Apr 11;45(8):1633-43
references.pmid: 11931617
references.citation: Mol Divers. 2009 Aug;13(3):295-300
references.pmid: 19205915
references.citation: Mol Divers. 2009 Nov;13(4):439-43
references.pmid: 19283503