title: Bioactive constituents from chinese natural medicines. XXXVI. Four new acylated phenylethanoid oligoglycosides, kankanosides J1, J2, K1, and K2, from stems of Cistanche tubulosa.
abstract: Four new acylated phenylethanoid oligoglycosides, kankanosides J(1) (1), J(2) (2), K(1) (3), and K(2) (4), were isolated from stems of Cistanche tubulosa (Orobanchaceae) together with isocampneoside I (5). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among them, 3-5 were found to inhibit D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes.
authors.affiliation: Pharmaceutical Research and Technology Institute, Kinki University, Higashi-osaka, Osaka, Japan.
authors.forename: Yingni
authors.initials: Y
authors.lastname: Pan
authors.forename: Toshio
authors.initials: T
authors.lastname: Morikawa
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Ninomiya
authors.forename: Katsuya
authors.initials: K
authors.lastname: Imura
authors.forename: Dan
authors.initials: D
authors.lastname: Yuan
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Muraoka
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D031671:Cistanche / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005688:Galactosamine / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; C550966:kankanoside; D005688:Galactosamine