title: Metabolic syndrome as a risk factor for postoperative kidney injury after off-pump coronary artery bypass surgery.
abstract: BACKGROUND
  Metabolic syndrome (MetS) is a clustering of risk factors, including dyslipidemia, hypertension, and increased plasma glucose levels, which increase the risk of cardiovascular disease and renal impairment. We retrospectively analyzed the relationship between MetS and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB).
  
  
  RESULTS
  Patients who underwent isolated OPCAB between January 2006 and December 2008 were identified. Patients were grouped by using the National Cholesterol Education Program-Adult Treatment Panel III criteria with body mass index instead of waist circumference. From a total of 740 patients, 320 patients (43.2%) were in the MetS group, and 420 patients (56.8%) were in the non-MetS group. Postoperative AKI occurred in 84 patients (26.2%) in the MetS group and 44 patients (10.5%) in the non-MetS group (P<0.05). Multivariate logistic regression identified diabetes mellitus (odds ratio (OR), 1.83; 95% confidence interval (CI), 1.12-3.00; P=0.02), chronic kidney disease (OR, 4.79; 95%CI, 2.85-8.07; P<0.001), MetS (OR, 3.14; 95%CI, 1.79-5.49; P=0.001), and emergency surgery (OR, 5.08; 95%CI, 1.01-25.6; P=0.05) as independent risk factors for AKI after OPCAB.
  
  
  CONCLUSIONS
  MetS is a prevalent risk factor for postoperative AKI after OPCAB, and aggressive treatments of its components could have reduced operative morbidity.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Soonchang
authors.initials: S
authors.lastname: Hong
authors.forename: Young-Nam
authors.initials: YN
authors.lastname: Youn
authors.forename: Kyung-Jong
authors.initials: KJ
authors.lastname: Yoo
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D015992:Body Mass Index; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors