title: The role of spectral-domain optical coherence tomography in the diagnosis of retinal angiomatous proliferation.
abstract: BACKGROUND
  We present the findings of spectral-domain optical coherence tomography (OCT) in 8 patients with retinal angiomatous proliferation.
  
  
  METHODS
  Eight patients with a known history of age-related macular degeneration presented with a recent decrease of visual acuity in one eye. On fundus examination, all patients showed an elevated macular lesion associated with intra- or subretinal hemorrhage and retinal hard exudates. Fluorescein and indocyanine-green (ICG) angiography, together with spectral-domain OCT (Optopol Copernicus SOCT), were performed.
  
  
  RESULTS
  Fluorescein angiography showed early hyperfluorescence with late leakage in all cases. A serous pigment epithelium detachment was present in 6 cases. ICG angiography showed a hot spot in the macular area. The OCT showed a serous pigment epithelium detachment in 6 cases and intraretinal cysts in all cases. The line crossing the ICG visible hot spot showed a greatly hyperreflective intraretinal lesion located at various depths inside the retina.
  
  
  CONCLUSIONS
  Spectral-domain OCT is a useful complementary tool to confirm the diagnosis of retinal angiomatous proliferation. Its high resolution and speed enables accurate localization of the angiomatous lesion.
authors.affiliation: Ophthalmological Center of Terrassière, Geneva, Switzerland. ipetropoulos@cot-ge.ch
authors.forename: I K
authors.initials: IK
authors.lastname: Petropoulos
authors.forename: M A
authors.initials: MA
authors.lastname: Matter
authors.forename: J M
authors.initials: JM
authors.lastname: Katsimpris
authors.forename: P M
authors.initials: PM
authors.lastname: Desmangles
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000798:Angiomatosis / Q000150:complications* / Q000473:pathology*; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D015861:Retinal Neovascularization / Q000150:complications* / Q000473:pathology*; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*