title: Bone mineral densities in patients with developmental dysplasia of the hip.
abstract: Bone mineral density (BMD) of the lumbar spine, ultradistal radius, and calcaneus were significantly higher in the developmental dysplasia of the hip (DDH) patients than in the controls. Therefore, our data suggest that BMDs at different skeletal sites are greater in patients with DDH than in healthy women.
  
  
  BACKGROUND
  DDH has been acknowledged as a potentially preosteoarthritic condition that results in the development of hip osteoarthritis. Patients with DDH have been reported to have abnormal morphology of the pelvis and spine. Additional research, including that of bone quality, needs to be conducted to elucidate the pathogenetic mechanism of this disease. We therefore sought to determine whether BMD differs between healthy women and women with DDH.
  
  
  METHODS
  We measured BMD in 40 women who were scheduled to undergo pelvic osteotomy for DDH (average age, 45.3 years) and in 31 healthy women used as age-matched controls (average age, 47.5 years). BMDs of the lumbar spine, radius, and calcaneus were measured.
  
  
  RESULTS
  BMDs of the lumbar spine, ultradistal radius, and calcaneus were significantly higher in the DDH patients than in the controls.
  
  
  CONCLUSIONS
  Therefore, our data suggest that BMDs at different skeletal sites are greater in patients with DDH than in healthy women.
authors.affiliation: Department of Orthopedic Surgery, Nagasaki Medical Center, 2-1001-1 Kubara, Omura, 852-8562, Japan. kokano@nmc.hosp.go.jp
authors.forename: K
authors.initials: K
authors.lastname: Okano
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Aoyagi
authors.forename: S
authors.initials: S
authors.lastname: Motokawa
authors.forename: H
authors.initials: H
authors.lastname: Shindo
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D015519:Bone Density / Q000502:physiology*; D002111:Calcaneus / Q000503:physiopathology; D016022:Case-Control Studies; D005260:Female; D006618:Hip Dislocation, Congenital / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008159:Lumbar Vertebrae / Q000503:physiopathology; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000209:etiology / Q000503:physiopathology; D011884:Radius / Q000503:physiopathology
references.citation: J Orthop Sci. 2008 Sep;13(5):401-4
references.pmid: 18843452
references.citation: Osteoporos Int. 1991 Sep;1(4):232-41
references.pmid: 1790410
references.citation: Curr Opin Rheumatol. 2000 Sep;12(5):464-7
references.pmid: 10990188
references.citation: Clin Rheumatol. 1990 Jun;9(2):193-203
references.pmid: 2390848
references.citation: Osteoporos Int. 1999;10(5):377-83
references.pmid: 10591835
references.citation: Bone. 2003 Jan;32(1):86-95
references.pmid: 12584040
references.citation: Acta Orthop Scand. 1998 Jun;69(3):259-65
references.pmid: 9703399
references.citation: J Bone Joint Surg Am. 1950 Oct;32 A(4):767-78
references.pmid: 14784485
references.citation: Aging Clin Exp Res. 2003 Oct;15(5):426-39
references.pmid: 14703009
references.citation: Arthritis Rheum. 1995 Jul;38(7):907-16
references.pmid: 7612040
references.citation: Arthritis Rheum. 2000 Jul;43(7):1450-5
references.pmid: 10902745
references.citation: Acta Orthop. 2005 Apr;76(2):149-58
references.pmid: 16097538
references.citation: J Rheumatol. 1999 Mar;26(3):622-6
references.pmid: 10090173
references.citation: J Bone Miner Res. 2000 Sep;15(9):1678-82
references.pmid: 10976988
references.citation: Semin Arthritis Rheum. 2005 Jun;34(6 Suppl 2):29-34
references.pmid: 16206954
references.citation: Arthritis Rheum. 1996 Jan;39(1):81-6
references.pmid: 8546742
references.citation: J Bone Joint Surg Am. 1979 Jan;61(1):15-23
references.pmid: 365863
references.citation: Bone. 2009 May;44(5):899-907
references.pmid: 19284975
references.citation: J Bone Joint Surg Am. 1954 Jun;36-A(3):451-75
references.pmid: 13163078
references.citation: J Orthop Sci. 2001;6(3):217-22
references.pmid: 11484113
references.citation: Clin Orthop Relat Res. 1989 Apr;(241):190-6
references.pmid: 2924462
references.citation: J Bone Joint Surg Am. 1950 Jul;32-A(3):519-31
references.pmid: 15428474
references.citation: Ann Rheum Dis. 1991 Jan;50(1):8-13
references.pmid: 1994877
references.citation: Rheumatology (Oxford). 2008 Oct;47(10):1452-60
references.pmid: 18495820
references.citation: Int Orthop. 2003;27(2):70-2
references.pmid: 12700927