Alternative photoinduced release of HNO or NO from an acyl nitroso compound, depending on environmental polarity.
A hydrophilic hetero-Diels-Alder cycloadduct was synthesized as a novel photocontrollable donor of reactive nitrogen species. Production of either nitric oxide (NO) or nitroxyl (HNO) was photoinduced from this compound, depending on the environmental polarity.
Matsuo
Kazuya
K
Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.
Nakagawa
Hidehiko
H
Adachi
Yusuke
Y
Kameda
Eri
E
Tsumoto
Hiroki
H
Suzuki
Takayoshi
T
Miyata
Naoki
N
D004578:Electron Spin Resonance Spectroscopy; D008401:Gas Chromatography-Mass Spectrometry; D009569:Nitric Oxide / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D009603:Nitroso Compounds / Q000737:chemistry*; D055668:Photochemical Processes; D026361:Reactive Nitrogen Species / Q000737:chemistry; D014466:Ultraviolet Rays
D009589:Nitrogen Oxides; D009603:Nitroso Compounds; D026361:Reactive Nitrogen Species; D009569:Nitric Oxide; C039900:nitroxyl