title: Lactic acidosis: recognition, kinetics, and associated prognosis.
abstract: Lactic acidosis is a common condition encountered by critical care providers. Elevated lactate and decreased lactate clearance are important for prognostication. Not all lactate in the intensive care unit is due to tissue hypoxia or ischemia and other sources should be evaluated. Lactate, in and of itself, is unlikely to be harmful and is a preferred fuel for many cells. Treatment of lactic acidosis continues to be aimed the underlying source.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, UHN 67, Portland, OR 97239, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Vernon
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Letourneau
mesh_terms: D000140:Acidosis, Lactic / Q000097:blood / Q000175:diagnosis / Q000378:metabolism*; D006801:Humans; D019344:Lactic Acid / Q000097:blood / Q000378:metabolism*; D011379:Prognosis
chemical_list: D019344:Lactic Acid