Hidradenitis suppurativa complicating naevus comedonicus: the possible influence of mechanical stress on the development of hidradenitis suppurativa.
Naevus comedonicus is a rare, benign hamartoma consisting of grouped abnormal hair follicles and, occasionally, associated with other diseases. We describe an infant who developed hidradenitis-like lesions in an inguinal naevus comedonicus following increased mechanical stress on the region. It is speculated that the degree of strain on a hair follicle is increased when its diameter is increased, leading to wall ruptures. We hypothesise that this serendipitous observation provides a model for the way mechanical stress can account for the development of hidradenitis suppurativa in some patients.
Dufour
Deirdre Nathalie
DN
Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Køgevej 7-13, Roskilde, Denmark. dndu@regionsjaelland.dk
Bryld
Lars Erik
LE
Jemec
Gregor B E
GB
D002908:Chronic Disease; D005260:Female; D006119:Groin; D018859:Hair Follicle / Q000002:abnormalities*; D006222:Hamartoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D017497:Hidradenitis Suppurativa / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D013314:Stress, Mechanical