[Relationship between clinical characteristics and primary and secondary products of lipid and protein peroxidation].
Recent studies showed that activation of free oxygen radicals and the resulting stress play a key role in the development of brain vascular lesions related to hypertensive disease and atherosclerosis leading to chronic cerebral ischemia. To recall, activation of oxidative stress precedes chronic cerebral ischemia and stroke. Therefore, detection of stress markers may be a step toward the development of a new method for the identification of groups at high risk of stroke among patients with the unfavourable course of cerebral ischemia. This study was focused on the relationship between lipid and protein peroxidation products and clinical manifestations of the disease.
Azizova
O A
OA
Solov'eva
E Iu
EIu
Mironova
O P
OP
Bekman
E M
EM
Baranova
O A
OA
Moskvina
S N
SN
Fedin
A I
AI
D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism*; D002545:Brain Ischemia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D011379:Prognosis; D050050:Protein Carbonylation; D012737:Sex Factors
D015415:Biomarkers; D001798:Blood Proteins; D008054:Lipid Peroxides; D008074:Lipoproteins; D008315:Malondialdehyde