Multiparticulate carriers for sun-screening agents.
Many molecular sunscreens penetrate into the skin causing photo-allergic and photo-toxic reactions as well as skin irritations establishing an urgent need for the development of a safer sunscreen formulation. The search for active substances, efficient combinations, and the design of novel vehicles or carriers has led to the implementation of new cosmetic systems in contrast to the classic forms such as creams or gels. Amongst various approaches utilized to improve performance of sunscreening agents, the use of multiparticulate delivery systems is gaining increasing attention amongst researchers. Multiparticulate delivery systems can be incorporated into gels, creams, liquids, powders or other formulations, and can release active agents depending on their temperature, moisture, friction, volatility of the entrapped ingredients or time. These systems also have the ability of scattering or reflecting incoming UV radiations and therefore can act as physical sunscreens on their own.
Jain
S K
SK
SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Chhattisgarh, India. suniljain25in@yahoo.com
Jain
N K
NK
D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008863:Microspheres; D013473:Sunscreening Agents / Q000008:administration & dosage / Q000737:chemistry*
D013473:Sunscreening Agents