title: Efficient synthesis of E-alpha-haloenones through chemoselective alkyne activation over allene with triazole-Au catalysts.
abstract: The E-alpha-haloenones were prepared through a triazole-Au complex (TriA-Au) catalyzed propargyl acetate rearrangement and sequential allene halogenation. The reactions proceeded with only 1% catalyst loading, giving the challenging kinetic products in excellent yields and good to excellent stereoselectivity. These results not only provided the first example for the synthesis of challenging kinetic E-haloenones, but also revealed triazole-Au complexes as effective catalysts in promoting chemoselective activation of alkynes over allenes.
authors.affiliation: C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.
authors.forename: Dawei
authors.initials: D
authors.lastname: Wang
authors.forename: Xiaohan
authors.initials: X
authors.lastname: Ye
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi