title: Sutureless tympanoplasty using acellular dermis.
abstract: OBJECTIVE
  A prospective randomized unblinded controlled trial was conducted by comparing acellular dermis with temporalis fascia as graft materials in tympanoplasty (type 1) in terms of operative time, postoperative pain, graft success rate, and audiologic outcome.
  
  
  METHODS
  Forty-two patients with (inactive) chronic suppurative otitis media of tubotympanic type were randomized, matched, and divided equally into 2 groups of 21 each. One group underwent tympanoplasty (type 1) via transcanal route using temporalis fascia graft and the other using acellular dermis. Both groups were compared for operative time, postoperative pain, graft success rate, and audiologic improvement in hearing.
  
  
  RESULTS
  There was a statistically significant reduction in operative time (P < .05) and postoperative pain (P < .05) in the acellular dermis group. However, there was no statistical difference in graft success rate (P > .05) and hearing improvement (P > .05) between both the groups.
  
  
  CONCLUSIONS
  Results of tympanoplasty using acellular dermis as graft material are comparable to that using temporalis fascia in terms of graft uptake and hearing improvement. However, tympanoplasty using acellular dermis has the advantage of shorter operative time and lesser postoperative pain.
authors.affiliation: Department of Otolaryngology and Head, Neck Surgery, MAM College and Assoc. LN Hospital, New Delhi, India.
authors.forename: Anoop
authors.initials: A
authors.lastname: Raj
authors.forename: Ankush
authors.initials: A
authors.lastname: Sayal
authors.forename: P K
authors.initials: PK
authors.lastname: Rathore
authors.forename: Ravi
authors.initials: R
authors.lastname: Meher
mesh_terms: D000293:Adolescent; D000328:Adult; D020405:Dermis / Q000166:cytology / Q000637:transplantation*; D005205:Fascia / Q000637:transplantation*; D006084:Graft Rejection; D006309:Hearing / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control; D011446:Prospective Studies; D013537:Sutures; D013703:Temporal Muscle; D013997:Time Factors; D016896:Treatment Outcome; D018058:Tympanic Membrane Perforation / Q000601:surgery; D014433:Tympanoplasty / Q000379:methods*; D055815:Young Adult