title: On the prebiotic potential of reduced oxidation state phosphorus: the H-phosphinate-pyruvate system.
abstract: H-Phosphinic acid and pyruvic acid, both plausible prebiotic chemicals, react selectively in water to build structural complexity including amide bond formation under remarkably mild conditions and oxidative coupling of P(1) compounds to condensed pyrophosphorus compounds.
authors.affiliation: School of Chemistry, University of Leeds, Leeds LS2 9JT, UK.
authors.forename: David E
authors.initials: DE
authors.lastname: Bryant
authors.forename: Katie E R
authors.initials: KE
authors.lastname: Marriott
authors.forename: Stuart A
authors.initials: SA
authors.lastname: Macgregor
authors.forename: Colin
authors.initials: C
authors.lastname: Kilner
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Pasek
authors.forename: Terence P
authors.initials: TP
authors.lastname: Kee
mesh_terms: D010084:Oxidation-Reduction; D010721:Phosphinic Acids / Q000737:chemistry*; D010758:Phosphorus / Q000737:chemistry*; D056692:Prebiotics; D019289:Pyruvic Acid / Q000737:chemistry*
chemical_list: D010721:Phosphinic Acids; D056692:Prebiotics; D010758:Phosphorus; D019289:Pyruvic Acid