title: Refractory erythromelalgia of the ears: response to mexiletine.
abstract: Erythromelalgia is a rare condition characterized by burning pain, erythema, swelling, and increased temperature usually in the extremities. We present an unusual presentation of erythromelalgia of the ears in a patient who has been refractory to multiple therapies and in whom relief of symptoms was achieved with the use of mexiletine. A review of clinical presentation, pathophysiology, and therapeutic options are presented.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Alejandra C
authors.initials: AC
authors.lastname: Vivas
authors.forename: Julia
authors.initials: J
authors.lastname: Escandon
authors.forename: Robert S
authors.initials: RS
authors.lastname: Kirsner
mesh_terms: D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004427:Ear Diseases / Q000188:drug therapy* / Q000503:physiopathology; D004431:Ear, External; D004916:Erythromelalgia / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008801:Mexiletine / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D008801:Mexiletine