title: Spread of adenovirus to geographically dispersed military installations, May-October 2007.
abstract: In mid-May 2007, a respiratory disease outbreak associated with adenovirus, serotype B14 (Ad14), was recognized at a large military basic training facility in Texas. The affected population was highly mobile; after the 6-week basic training course, trainees immediately dispersed to advanced training sites worldwide. Accordingly, enhanced surveillance and control efforts were instituted at sites receiving the most trainees. Specimens from patients with pneumonia or febrile respiratory illness were tested for respiratory pathogens by using cultures and reverse transcription-PCR. During May through October 2007, a total of 959 specimens were collected from 21 sites; 43.1% were adenovirus positive; the Ad14 serotype accounted for 95.3% of adenovirus isolates. Ad14 was identified at 8 sites in California, Florida, Mississippi, Texas, and South Korea. Ad14 spread readily to secondary sites after the initial outbreak. Military and civilian planners must consider how best to control the spread of infectious respiratory diseases in highly mobile populations traveling between diverse geographic locations.
authors.affiliation: United States Air Force School of Aerospace Medicine, San Antonio, Texas, USA.
authors.forename: Jill S
authors.initials: JS
authors.lastname: Trei
authors.forename: Natalie M
authors.initials: NM
authors.lastname: Johns
authors.forename: Jason L
authors.initials: JL
authors.lastname: Garner
authors.forename: Lawrence B
authors.initials: LB
authors.lastname: Noel
authors.forename: Brian V
authors.initials: BV
authors.lastname: Ortman
authors.forename: Kari L
authors.initials: KL
authors.lastname: Ensz
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Johns
authors.forename: Michel L
authors.initials: ML
authors.lastname: Bunning
authors.forename: Joel C
authors.initials: JC
authors.lastname: Gaydos
mesh_terms: D000258:Adenovirus Infections, Human / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D000260:Adenoviruses, Human / Q000302:isolation & purification*; D000293:Adolescent; D000328:Adult; D004196:Disease Outbreaks; D005260:Female; D005843:Geography; D006801:Humans; D008297:Male; D008889:Military Personnel; D011024:Pneumonia, Viral / Q000453:epidemiology / Q000635:transmission / Q000821:virology; D011159:Population Surveillance; D056910:Republic of Korea / Q000453:epidemiology; D013997:Time Factors; D014195:Travel; D014481:United States / Q000453:epidemiology
references.citation: J Clin Microbiol. 2004 Apr;42(4):1686-93
references.pmid: 15071026
references.citation: Am J Hyg. 1955 Nov;62(3):283-94
references.pmid: 13268418
references.citation: Emerg Infect Dis. 2000 Jul-Aug;6(4):415-9
references.pmid: 10905981
references.citation: J Immunol. 1960 Jun;84:562-8
references.pmid: 13841541
references.citation: Clin Infect Dis. 2000 Sep;31(3):663-70
references.pmid: 11017812
references.citation: J Infect Dis. 1956 Sep-Oct;99(2):182-7
references.pmid: 13376912
references.citation: Vaccine. 2008 Jun 2;26(23):2890-8
references.pmid: 18448211
references.citation: Am J Epidemiol. 1973 Mar;97(3):187-98
references.pmid: 4348245
references.citation: Am J Epidemiol. 1969 Jan;89(1):25-50
references.pmid: 4303049
references.citation: J Clin Microbiol. 2005 Nov;43(11):5743-52
references.pmid: 16272512
references.citation: J Infect Dis. 2007 Nov 15;196(10):1436-7
references.pmid: 18008220
references.citation: Antimicrob Agents Chemother (Bethesda). 1965;5:55-8
references.pmid: 4286921
references.citation: Vaccine. 2006 Apr 5;24(15):2835-42
references.pmid: 16480793
references.citation: MMWR Morb Mortal Wkly Rep. 2007 Nov 16;56(45):1181-4
references.pmid: 18004235
references.citation: J Infect Dis. 2007 Nov 15;196(10):1465-73
references.pmid: 18008225