title: Treatment of a tardive dyskinesia patient with temporomandibular disorder: a case report.
abstract: This case report presents a patient with tardive dyskinesia who also suffered from masticatory muscle pain and temporomandibular joint osteoarthrosis. The patient was treated with clozapine in gradually increasing doses and two injections of botulinum toxin type A one year apart. Involuntary movements of mandibular clenching and bruxing disappeared and pain was relieved to a great extent. Reappearances of dyskinetic movements and pain were observed during the follow-up period of 1.5 years.
authors.affiliation: Department of Dentistry, Dumlupinar University, Merkez Kampus, Tavsanli Yolu 10. Km, 43270, Kutahya, Turkey. gurelp@gmail.com
authors.forename: Gurel
authors.initials: G
authors.lastname: Pekkan
authors.forename: Alev
authors.initials: A
authors.lastname: Kilicoglu
authors.forename: Demet Ilhan
authors.initials: DI
authors.lastname: Algin
mesh_terms: D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D002012:Bruxism / Q000188:drug therapy* / Q000209:etiology; D003024:Clozapine / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000150:complications* / Q000188:drug therapy; D005157:Facial Pain / Q000188:drug therapy* / Q000209:etiology; D005500:Follow-Up Studies; D018756:GABA Antagonists / Q000627:therapeutic use; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009465:Neuromuscular Agents / Q000627:therapeutic use; D010003:Osteoarthritis / Q000209:etiology; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D014150:Antipsychotic Agents; D018756:GABA Antagonists; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A; D003024:Clozapine; D006220:Haloperidol