Abiotrophia defectiva endophthalmitis with retinal involvement and infiltrative keratitis: case report and review of the literature.
We report the exceptional case of a severe intraocular Abiotrophia defectiva infection which developed after cataract surgery. Retinal involvement as a complication of A. defectiva endophthalmitis or the combination of acute-onset endophthalmitis with infiltrative keratitis caused by this pathogen has not been described. Moreover, our report represents the first documented ocular A. defectiva infection in Germany. A. defectiva was identified using biotyping and 16S ribosomal RNA gene sequence analysis. Despite vigorous antimicrobial therapy and repeated ocular surgery, visual outcome was poor.
Horstkotte
M A
MA
Institut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. hor@labor-froreich.de
Dobinsky
S
S
Rohde
H
H
Knobloch
J K-M
JK
Hassenstein
A
A
Kalitzky
M
M
Richard
G
G
Linke
S J
SJ
D056567:Aerococcaceae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D000368:Aged; D015373:Bacterial Typing Techniques; D002387:Cataract Extraction / Q000009:adverse effects; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D009877:Endophthalmitis / Q000150:complications / Q000382:microbiology*; D005260:Female; D005858:Germany; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007634:Keratitis / Q000150:complications / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012173:Retinitis / Q000150:complications / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D013530:Surgical Wound Infection / Q000382:microbiology
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S
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