title: Facial lymphoedema as an indicator of terminal disease in oral HIV-associated Kaposi sarcoma.
abstract: Rapidly progressive facial lymphoedema developing concurrently with, or immediately after rapid enlargment of oral Kaposi sarcoma (KS) in HIV-seropositive highly active antiretroviral treatment (HAART)-naïve subjects, foretokens death. We present here an unusual case of HIV-KS in an 11-year-old HIV-seropositive HAART-naïve boy. Our patient's KS disease had had a fulminant course characterised by rapidly progressing oral HIV-KS, resorption of the mandibular alveolar bone process beneath some of the HIV-KS lesions, and rapidly progressive facial lymphoedema. He died 3 weeks after the onset of facial lymphoedema.
authors.affiliation: Department of Periodontology and Oral Medicine, School of Oral Health Sciences, University of Limpopo, Medunsa Campus, South Africa. lfeller@ul.ac.za
authors.forename: L
authors.initials: L
authors.lastname: Feller
authors.forename: R A G
authors.initials: RA
authors.lastname: Khammissa
authors.forename: N H
authors.initials: NH
authors.lastname: Wood
authors.forename: R J
authors.initials: RJ
authors.lastname: Jose
authors.forename: J
authors.initials: J
authors.lastname: Lemmer
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D001862:Bone Resorption / Q000175:diagnosis; D002648:Child; D018450:Disease Progression; D005145:Face; D017809:Fatal Outcome; D005887:Gingival Neoplasms / Q000175:diagnosis; D006801:Humans; D008209:Lymphedema / Q000175:diagnosis*; D008297:Male; D008336:Mandibular Diseases / Q000175:diagnosis; D009062:Mouth Neoplasms / Q000175:diagnosis*; D012514:Sarcoma, Kaposi / Q000175:diagnosis*; D014062:Tongue Neoplasms / Q000175:diagnosis