Monomethylamine as a nitrogen source for a nonmethylotrophic bacterium, Agrobacterium tumefaciens.
Monomethylamine can be used by nonmethylotrophs as a sole nitrogen source but not as a carbon source; however, little is known about the genes and enzymes involved. The gamma-glutamylmethylamide/N-methylglutamate pathway for monomethylamine utilization by methylotrophs has recently been resolved. We have identified genes encoding key enzymes of this pathway in nonmethylotrophs (e.g., Agrobacterium tumefaciens) and demonstrated that this pathway is also involved in the utilization of monomethylamine as a nitrogen source by nonmethylotrophs.
Chen
Yin
Y
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
McAleer
Kathryn L
KL
Murrell
J Colin
JC
D016960:Agrobacterium tumefaciens / Q000201:enzymology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D023061:Gene Order; D053858:Metabolic Networks and Pathways / Q000235:genetics; D008744:Methylamines / Q000378:metabolism*; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism*
D008744:Methylamines; D002244:Carbon; C027451:methylamine; D009584:Nitrogen
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