Homology Modelling of Human E1 Ubiquitin Activating Enzyme.
Human E1 is a key player in protein ubiquitination, however the E1 structure is not available. In this paper, we describe the derivation of a human E1 structure using molecular modelling based on the crystal structure of S. cerevisiae E1 and M. Musculus E1. Key interactions between our E1 model and ubiquitin are also discussed.
Brahemi
Ghali
G
Welsh School of Pharmacy, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff, Wales, CF10 3NB, U.K.
Burger
Angelika M
AM
Westwell
Andrew D
AD
Brancale
Andrea
A
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