Nuclear ploidy and intensity of proliferation of hepatocellular cancer cells.
Comparative morphometric and densitometric study of tumor cells and adjacent hepatocyte nuclei was carried out in hepatocellular cancer. Enlargement of the nuclei and increase in DNA content and index of proliferation of Ki-67 tumor cells inversely correlated with differentiation degree of hepatocellular cancer, which reflects the regularity of staged development of tumors.
Shchegolev
A I
AI
Department of Pathology, A V Vishnevsky Institute of Surgery, Moscow, Russia. shegolev@ixv.comcor.ru
Dubova
E A
EA
D000293:Adolescent; D000328:Adult; D000368:Aged; D049109:Cell Proliferation; D003720:Densitometry; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008113:Liver Neoplasms / Q000235:genetics* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D055815:Young Adult