Catecholamine plasma levels following immune stimulation with rabies vaccine in dogs selected for their paw preferences.
Epinephrine and norepinephrine plasma levels were assessed in dogs in relation to paw preference following an immune challenge with rabies vaccine. The results showed that both catecholamines increased after the vaccine administration, confirming the main role of the sympathetic nervous system in the modulation activity between the brain and the immune system. Moreover, ambidextrous dogs showed a significantly higher increase of epinephrine levels 8 days after immunization with respect to right- and left-pawed dogs, suggesting that the biological activity of this molecule could be key for a different immune response with regard to laterality.
Siniscalchi
Marcello
M
Department of Animal Production, University of Bari, Strada Prov.le per Casamassima, Km 3, 70010 Valenzano, Bari, Italy. m.siniscalchi@veterinaria.uniba.it
Sasso
Raffaella
R
Pepe
Anna M
AM
Dimatteo
Salvatore
S
Vallortigara
Giorgio
G
Quaranta
Angelo
A
D000818:Animals; D004285:Dogs; D004837:Epinephrine / Q000097:blood*; D005260:Female; D007839:Functional Laterality; D008297:Male; D015213:Neuroimmunomodulation; D009638:Norepinephrine / Q000097:blood*; D011819:Rabies Vaccines / Q000276:immunology*
D011819:Rabies Vaccines; D009638:Norepinephrine; D004837:Epinephrine