Bone loss across the menopausal transition.
The Study of Women's Health Across the Nation (SWAN) is an NIH-funded, multidisciplinary, longitudinal observational study of middle-aged U.S. women of multiple ethnicities in or near Boston, Newark, Pittsburgh, Detroit, Chicago, Oakland, and Los Angeles. SWAN measures multiple variables annually, including spine and hip areal bone mineral density (aBMD), serum and urine indices of bone remodeling, and pituitary, ovarian, and adrenal hormones. This chapter outlines the findings of the SWAN study so far.
Neer
Robert M
RM
Massachusetts General Hospital, Boston, Massachusetts, USA. rneer@partners.org
D015415:Biomarkers / Q000032:analysis; D016723:Bone Remodeling / Q000502:physiology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008593:Menopause / Q000208:ethnology / Q000502:physiology*; D015337:Multicenter Studies as Topic; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology; D016387:Women's Health
D015415:Biomarkers
Osteoporos Int. 2003 May;14(3):191-7
12730778
Osteoporos Int. 2003 Jan;14(1):44-52
12577184
J Clin Endocrinol Metab. 2002 Jul;87(7):3051-6
12107200
J Clin Endocrinol Metab. 2006 Apr;91(4):1261-7
16403818
J Clin Endocrinol Metab. 2008 Mar;93(3):861-8
18160467
Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14925-30
17003115
J Bone Miner Res. 2003 Jun;18(6):1020-7
12817754
J Clin Endocrinol Metab. 2002 Jul;87(7):3057-67
12107201
J Bone Miner Res. 2001 Feb;16(2):417-26
11204442
Cell. 2006 Apr 21;125(2):247-60
16630814