[Diagnosis and treatment of cervical Castleman disease presenting as a neck mass].
OBJECTIVE
To investigate the clinical and pathological features, diagnosis and treatment of Castleman disease (CD).


METHODS
Clinical features and related information on diagnosis and treatment of eight cases of CD were retrospectively analyzed. The size of involved lymph nodes ranged from (2 cm x 2 cm x 3 cm) - (4 cm x 3 cm x 2 cm). The lymph nodes were found in level I (1 case), level II (3 cases), level III (3 cases) and level IV (1 case). CT examination in eight patients showed the lesions manifested as ellipse soft masses. Dynamic contrast CT scan in four patients showed ring-enhanced area around the masses. Blood routine examination in eight patients were generally normal, with six patients had mild anemia.


RESULTS
Based on the clinical classification, all lesions in this group were localized CD. Histopathology indicated that all lesions were of hyaline-vascular type. After surgery, there was no recurrence during the follow-up period.


CONCLUSIONS
Patients with localized CD mainly have lymphadenectasis in a single location. The CT scan can give some evidence. Surgery should be given first priority.
Wang
Jun
J
Department of Otorhinolaryngology-Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun 130031, China.
Xin
Wei-hong
WH
Sun
Yu-xin
YX
Chen
Qian-qian
QQ
Meng
Cui-da
CD
Yue
Jian
J
Kan
Ying-nan
YN
Zhu
Jia-jing
JJ
Yang
Zhan-quan
ZQ
Yao
Ping
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D005871:Castleman Disease / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D012189:Retrospective Studies; D055815:Young Adult