title: Genetic and familial factors influencing breast, colon, prostate and lung cancers.
abstract: Knowledge of cancer genetics is advancing our biological understanding of breast, colon, prostate and lung cancers. A family history of any one of these four types of cancer can increase an individual's personal risk to also develop a malignancy. For some families, genetic testing, in combination with genetic counseling, can be a helpful way to identify a hereditary cancer predisposition gene or establish a cancer risk management plan. In this paper, we will review the current state of knowledge surrounding genetic factors influencing breast, colon, prostate and lung cancer.
authors.affiliation: Sanford Women's Health & Sanford Children's Specialty Clinic, South Dakota, USA.
authors.forename: Quinn P
authors.initials: QP
authors.lastname: Stein
authors.forename: Jason D
authors.initials: JD
authors.lastname: Flanagan
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000235:genetics*; D005260:Female; D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics*; D008297:Male; D011471:Prostatic Neoplasms / Q000235:genetics*; D018570:Risk Assessment; D012307:Risk Factors