Stereoselective synthesis of tetrasubstituted alkenylboronates via 1,1-organodiboronates.
The stereoselective synthesis of tetrasubstituted alkenylboronates was established via the lithiation/nucleophilic addition reaction of 1,1-organodiboronates to carbonyl compounds. The present approach enables the facile and practical synthesis of tetrasubstituted olefins, which are useful synthetic intermediates for further functionalizations.
Endo
Kohei
K
Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Tokyo 169-8555, Japan. kendo@aoni.waseda.jp
Hirokami
Munenao
M
Shibata
Takanori
T
D001897:Boronic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D001897:Boronic Acids