Facile and efficient synthesis of functionalized iminothiopyran and isothiochromen via one-pot multicomponent reactions.
An efficient synthesis of 6H-6-iminothiopyran-2,3-dicarboxylate and 1H-isothiochromene-3,4-dicarboxylate derivatives via one-pot reactions between acetylenic esters, aryl isothiocyanates and enaminones in dichloromethane at room temperature is described. The mild reaction condition, high yields and the new products are advantages of our method.
Hamadi
Hosein
H
Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
Khoobi
Mehdi
M
Hossaini
Zinatossadat
Z
Shafiee
Abbas
A
D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D006573:Heterocyclic Compounds, 1-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
D001578:Benzopyrans; D019086:Bridged Bicyclo Compounds, Heterocyclic; D006573:Heterocyclic Compounds, 1-Ring; D011714:Pyrans
J Am Chem Soc. 2006 Aug 16;128(32):10354-5
16895386
Acc Chem Res. 2003 Dec;36(12):899-907
14674781
Angew Chem Int Ed Engl. 2000 Sep 15;39(18):3168-3210
11028061
J Am Chem Soc. 2005 Jan 19;127(2):605-13
15643884
Bioorg Med Chem Lett. 2002 Nov 4;12(21):3171-4
12372526
J Med Chem. 2000 Jul 27;43(15):2871-82
10956195
J Med Chem. 2002 Apr 11;45(8):1633-43
11931617
Mol Divers. 2009 Aug;13(3):295-300
19205915
Mol Divers. 2009 Nov;13(4):439-43
19283503