title: Efficacy of healing process of bone defects after apicectomy: results after 6 and 12 months.
abstract: The aim of this study was to assess the efficacy of selected surgical treatment techniques of bone defects after apectomy. A total of 106 postresection bone defects, located in maxilla and mandible were included in the study: the defects were treated with resorbable collagen membrane (BG I- 26 defects), xenogenic bovine material (BOC II- 30 defects) and xenogenic bovine material with platelet rich plasma (BOC/PRP III- 20 defects). In the control group the defects were left to heal spontaneously. Clinical and radiological assessment was performed at 6 and 12 months after the procedures. The analysis among groups revealed higher efficiency of the method of treatment that uses guide bone regeneration in comparison to the group in both post-operative control periods. After 6 months, the differences were statistically significant for each group using the regeneration methods, but after 12 months only for the BOC/PRP group. Treatment using selected guided bone regeneration techniques proved superior to the control group in both observation periods, but after 6 as well 12 months the best results in the BOC/PRP group were observed.
authors.affiliation: Department of Oral Surgery, University of Medicine, Wroclaw, Poland. marzena.dominiak@wp.pl
authors.forename: M
authors.initials: M
authors.lastname: Dominiak
authors.forename: K
authors.initials: K
authors.lastname: Lysiak-Drwal
authors.forename: T
authors.initials: T
authors.lastname: Gedrange
authors.forename: M
authors.initials: M
authors.lastname: Zietek
authors.forename: H
authors.initials: H
authors.lastname: Gerber
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects / Q000502:physiology; D018786:Bone Substitutes / Q000008:administration & dosage; D002417:Cattle; D002648:Child; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008297:Male; D008437:Maxilla / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D008964:Molar, Third / Q000601:surgery*; D019647:Oral Surgical Procedures / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology; D055815:Young Adult
chemical_list: D018786:Bone Substitutes