Three new compounds from the marine fungus Penicillium sp.
Continuous research on the ethyl acetate extract of the fermentation broth of the marine fungus Y26-02 (Penicillium sp.) led to the purification of one known and three new compounds. Their structures were elucidated, respectively, as butyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl) acetate (1), 4-hydroxyphenethyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl) acetate (2), 3-hydroxybenzyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl) acetate (3), and desoxypatulinic acid (4) on the basis of their spectroscopic and physico-chemical properties.
Wu
Hong-Hua
HH
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Tian
Li
L
Feng
Bao-Min
BM
Li
Zhi-Feng
ZF
Zhang
Qi-Hui
QH
Pei
Yue-Hu
YH
D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*; D011714:Pyrans / Q000737:chemistry / Q000302:isolation & purification*
C549186:3-hydroxybenzyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl)acetate; C549187:4-hydroxyphenethyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl)acetate; D011714:Pyrans; C549185:butyl 2-(4-oxo-5,6-dihydro-2H-pyran-3-yl) acetate