title: [Effect of combination pretreatment of polyethylene glycol solution and magnesium hydroxide for colonoscopy].
abstract: OBJECTIVE
  This study was designed to compare the efficacy and patient tolerance between standard bowel preparation using 4 liters of polyethylene glycol (PEG) solution and 4 liters of PEG preceded by the osmotic laxative, magnesium hydroxide in constipation and non-constipation group.
  
  
  METHODS
  173 outpatient colonoscopy, except for three patients who were not taking magnesium, were divided into constipation and non-constipation group. Then, the patients were randomly assigned to receive 4-liter of PEG solution or 4-liter of PEG plus magnesium hydroxide. The quality of bowel preparation was assessed using Ottawa scale, and satisfaction score was assessed using questionnaires. Solid stool, cecal intubation time, compliance, and side effects were assessed.
  
  
  RESULTS
  Non-constipation group showed no significant differences between two groups. In constipation group, 4-liter PEG solution plus magnesium hydroxide induced the more effective colonic preparation (Ottawa scale 2.47+/-0.99 vs. 5.92+/-2.39, p<0.05), and less solid stool (0.67+/-0.72 vs. 1.38+/-0.65, p<0.05) compared with 4-liter PEG solution.
  
  
  CONCLUSIONS
  Bowel preparation with magnesium hydroxide and 4 liters of PEG solution might reduce solid stool in constipation group, but could not improve preparation quality.
authors.affiliation: Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
authors.forename: Eun Kyung
authors.initials: EK
authors.lastname: Shin
authors.forename: Seun Ja
authors.initials: SJ
authors.lastname: Park
authors.forename: Kyu Jong
authors.initials: KJ
authors.lastname: Kim
authors.forename: Won
authors.initials: W
authors.lastname: Moon
authors.forename: Moo In
authors.initials: MI
authors.lastname: Park
authors.forename: Dong Han
authors.initials: DH
authors.lastname: Lim
authors.forename: Eun Ho
authors.initials: EH
authors.lastname: Park
authors.forename: Jee Suk
authors.initials: JS
authors.lastname: Lee
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003113:Colonoscopy; D005260:Female; D005751:Gastric Lavage / Q000379:methods*; D006801:Humans; D008276:Magnesium Hydroxide / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D011795:Surveys and Questionnaires
chemical_list: D011092:Polyethylene Glycols; D008276:Magnesium Hydroxide