Synthesis and antipsychotic and anticonvulsant activity of some new substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles.
A novel substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles (4a-j), (5a-j) and (6a-j) were synthesized and screened for their antipsychotic and anticonvulsant activities. It is concluded from the results compound 6j showed promising antipsychotic as well as anticonvulsant activity.
Kaur
Hemlata
H
Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Garh Road, Meerut 250004, Uttar Pradesh, India.
Kumar
Sunil
S
Vishwakarma
Pinki
P
Sharma
Monica
M
Saxena
K K
KK
Kumar
Ashok
A
D000927:Anticonvulsants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D014150:Antipsychotic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D012640:Seizures / Q000517:prevention & control; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity
D000927:Anticonvulsants; D014150:Antipsychotic Agents; D002227:Carbazoles; D010069:Oxadiazoles; D013830:Thiadiazoles