title: Synthesis, spectral characterization and antimicrobial evaluation of Schiff base Cu (II), Ni (II) and Co (II) complexes.
abstract: M(II) complexes of the type [HLCu(2)Cl(3)], [HLCu(2)(O(CO)CH(3))(3)], [HLM(2)Cl(4)(H(2)O)(3)] and [HLM(2)(OC(O)CH(3))(4)(H(2)O)(3)], where M=Ni(II), Co(II) have been synthesized by condensation of 3-acyl-2-one indol and hydrazinecarbothioamide (2:1) in the presence of divalent metal salt in methanolic medium. The complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structural configuration have been determined by various spectroscopic (electronic, IR, (1)H NMR, (13)C NMR, GCMS) techniques. Electronic and magnetic moments of the complexes indicate that the geometries of the metal centers are either distorted octahedral, or square planer. These metal complexes were also tested for their antibacterial and antifungal activities to assess their inhibiting potential.
authors.affiliation: Department of Chemistry, Vardhaman College, Bijnor 246701, Uttar Pradesh, India.
authors.forename: Gajendra
authors.initials: G
authors.lastname: Kumar
authors.forename: Dharmendra
authors.initials: D
authors.lastname: Kumar
authors.forename: Shoma
authors.initials: S
authors.lastname: Devi
authors.forename: Rajeev
authors.initials: R
authors.lastname: Johari
authors.forename: C P
authors.initials: CP
authors.lastname: Singh
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004583:Electrons; D005658:Fungi / Q000187:drug effects; D008280:Magnetics; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D012545:Schiff Bases / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D000890:Anti-Infective Agents; D009942:Organometallic Compounds; D012545:Schiff Bases; D003035:Cobalt; D003300:Copper; D009532:Nickel