Microwave ablation: results with double 915 MHz antennae in ex vivo bovine livers.
OBJECTIVE
To investigate the settings for the optimal microwave ablation geometry with the simultaneous application of double 915 MHz antennae in ex vivo bovine livers, so as to provide the technical basis for treating large liver tumor in one ablation session.


METHODS
MWAs were performed on ex vivo bovine livers by simultaneously application of double 915 MHz internally cooled-shaft antennae. Four power settings (50, 60, 70 and 80 W) were used during MWAs, while application time was fixed at 10 min. Three inter-antenna distances (2.0, 2.5 and 3.0 cm) were used. Diameters and shapes of the coagulation zones were observed on gross specimens.


RESULTS
(1) The coagulation shape was related to the inter-antenna distance, which was most spherical at an inter-antenna distance of 2.0 cm. A recess of the coagulation zone was observed at an inter-antenna distances of 2.5 and 3.0 cm. (2) The long-axis and short-axis coagulation diameter enlarged with increasing power output. However, there were no significant differences in the coagulation diameters between 70 and 80 W (P>0.05). More desirable coagulation geometry could be obtained by simultaneous application of double antennae at 70 W for 10 min with an inter-antenna distance of 2.0 cm, the long-axis and short-axis coagulation diameter were 6.95 ± 0.32 cm and 5.30 ± 0.22 cm, respectively.


CONCLUSIONS
Simultaneous application of double 915 MHz antennae can generate large coagulation zones with desirable shape which may be advantageous for treating large liver tumor in one ablation session.
Shi
Wenyuan
W
Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.
Liang
Ping
P
Zhu
Qiang
Q
Yu
Xiaoling
X
Shao
Qiujie
Q
Lu
Tong
T
Wang
Yang
Y
Dong
Baowei
B
D000818:Animals; D017115:Catheter Ablation / Q000295:instrumentation*; D002417:Cattle; D004867:Equipment Design; D066298:In Vitro Techniques; D008099:Liver / Q000601:surgery*; D008872:Microwaves / Q000627:therapeutic use*