title: Metastatic ovarian serous carcinoma presenting as inflammatory breast cancer: a case report.
abstract: A 42-year-old woman presented with localized irritation, erythema and sharp pain in the one breast. After unsuccessful treatment for mastitis, an oncology consultation was obtained. A breast biopsy revealed an invasive carcinoma and a diagnosis of inflammatory breast cancer was made. The patient was treated with neo-adjuvant chemotherapy and subsequently underwent bilateral mastectomy. A total abdominal hysterectomy and bilateral salpingo-oophorectomy was also performed at the same time due to the presence of a pelvic mass. Morphologic and immunohistochemical examination of the specimens helped to clarify the correct diagnosis of primary ovarian carcinoma with widespread metastases to bilateral breasts.
authors.affiliation: Department of Pathology, Magee-Women's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Gingell
authors.forename: Amber
authors.initials: A
authors.lastname: Samuel
authors.forename: Denise
authors.initials: D
authors.lastname: Haynik
authors.forename: William
authors.initials: W
authors.lastname: McBee
authors.forename: Joseph
authors.initials: J
authors.lastname: Kelley
authors.forename: Kristin
authors.initials: K
authors.lastname: Zorn
authors.forename: Rohit
authors.initials: R
authors.lastname: Bhargava
mesh_terms: D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D001943:Breast Neoplasms / Q000097:blood / Q000235:genetics / Q000556:secondary* / Q000628:therapy; D018394:CA-125 Antigen / Q000097:blood; D018284:Cystadenocarcinoma, Serous / Q000097:blood / Q000235:genetics / Q000556:secondary* / Q000628:therapy; D004273:DNA, Neoplasm / Q000235:genetics; D005260:Female; D024522:Genes, BRCA2; D006651:Histocytochemistry; D006801:Humans; D010051:Ovarian Neoplasms / Q000097:blood / Q000235:genetics / Q000473:pathology* / Q000628:therapy
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; C090797:CA 27-29 antigen; D018394:CA-125 Antigen; D004273:DNA, Neoplasm