title: A novel profluorescent probe for detecting oxidative stress induced by metal and H(2)O(2) in living cells.
abstract: A profluorescent probe that has no fluorescent response to H(2)O(2), iron or copper ions but can be readily activated in the presence of both H(2)O(2) and Fe (or Cu) ion has been developed; the probe is capable of detecting oxidative stress promoted by Fe (or Cu) and H(2)O(2) (i.e. the Fenton reaction conditions) in living cells.
authors.affiliation: Department of Chemistry and Biochemistry, University of Massachusetts, Dartmouth, MA 02747, USA.
authors.forename: Yibin
authors.initials: Y
authors.lastname: Wei
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Liu
authors.forename: Maolin
authors.initials: M
authors.lastname: Guo
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival; D003300:Copper / Q000494:pharmacology*; D005456:Fluorescent Dyes / Q000032:analysis* / Q000138:chemical synthesis / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D007501:Iron / Q000494:pharmacology*; D015394:Molecular Structure; D009447:Neuroblastoma / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects*; D013237:Stereoisomerism
chemical_list: D005456:Fluorescent Dyes; D003300:Copper; D006861:Hydrogen Peroxide; D007501:Iron
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