Sporothrix schenckii meningitis in AIDS during immune reconstitution syndrome.
Sporotrichosis is a fungal disease usually restricted to the cutaneous and lymphatic systems. Visceral involvement is unusual. To date, only 21 cases of sporotrichosis meningitis have been reported, some of these associated with immunosuppression. According to the reported cases, difficulty establishing the correct diagnosis is almost the rule which, undoubtedly, is associated with a worse prognosis. In this report, two HIV infected patients are described who developed meningitis due to Sporothrix schenckii associated with immune reconstitution inflammatory syndrome. This is the first report of sporotrichosis meningitis associated with immune reconstitution inflammatory syndrome in AIDS patients.
Galhardo
Maria Clara Gutierrez
MC
Evandro Chagas Clinical Research Institute (IPEC), Oswaldo Cruz Foundation (FIOCRUZ), Avenida Brasil, Rio de Janeiro, Brazil.
Silva
Marcus Tulius T
MT
Lima
Marco Antonio
MA
Nunes
Estevão Portela
EP
Schettini
Luiz Eduardo C
LE
de Freitas
Rodrigo Fernandes
RF
Paes
Rodrigo de Almeida
Rde A
Neves
Elizabeth de Sousa
Ede S
do Valle
Antonio Carlos Francesconi
AC
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging / Q000382:microbiology; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications*; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000209:etiology*; D013175:Sporothrix / Q000302:isolation & purification*; D013174:Sporotrichosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D000666:Amphotericin B