Two novel sulfur compounds from the seeds of Raphanus sativus L.
The seeds of Raphanus sativus L., known as Lai-fu-zi in traditional Chinese Medicine, are always roasted before clinical use for avoiding nausea. During an investigation of the chemical difference between roasted and pre-roasted products, two novel sulfur-containing compounds, which mainly existed in the pre-roasted products, were isolated. Their structures and absolute configurations were established by spectroscopic and X-ray diffraction analysis.
Zhang
Xin
X
School of Chinese Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Liu
Hong-Bing
HB
Jia
Jing-Jing
JJ
Lv
Wen-Hai
WH
D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D016480:Helicobacter pylori / Q000187:drug effects; D006358:Hot Temperature; D006801:Humans; D008516:Medicine, Chinese Traditional; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D015394:Molecular Structure; D009325:Nausea / Q000517:prevention & control; D031224:Raphanus / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry; D013457:Sulfur Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D004365:Drugs, Chinese Herbal; C549171:O-ethyl N-(E)-4-(methylsulfinyl)but-3-enylcarbamothioate; C549172:S-6-(methylsulfinyl)methyl-1,3-thiazinan-2-thione; D013457:Sulfur Compounds