Substrate-controlled and organocatalytic asymmetric synthesis of carbocyclic amino acid dipeptide mimetics.
The asymmetric synthesis of a carbocyclic delta-amino acid representing the P(2)/P(3) subunit of a nonpeptidic truncated peptidomimetic molecule is described relying on two independent approaches.
Hanessian
Stephen
S
Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-ville, Montréal, QC H3C 3J7, Canada. stephen.hanessian@umontreal.ca
Maji
Dilip K
DK
Govindan
Subramaniyan
S
Matera
Riccardo
R
Tintelnot-Blomley
Marina
M
D000146:Acids, Carbocyclic / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D040761:Biomimetic Materials / Q000138:chemical synthesis*; D002384:Catalysis; D004151:Dipeptides / Q000138:chemical synthesis*; D015394:Molecular Structure
D000146:Acids, Carbocyclic; D000596:Amino Acids; D004151:Dipeptides