Inflammatory myoglandular polyps: a case series of four patients and review of the literature.
BACKGROUND
Inflammatory myoglandular polyp (IMGP) is a nonneoplastic colorectal polyp. Only a small number of cases have been reported, and the pathogenesis remains unclear.


METHODS
We analyzed colonoscopy and histologic findings in 4 patients with IMGP. Histologic confirmation of the inflammatory granulation tissue in the lamina propria, proliferation of smooth muscle, and hyperplastic glands with variable cystic changes formed the criteria for the selection of patients.


RESULTS
We treated four cases of IMGP and reviewed the literature on this disease. Three cases were located in the sigmoid colon or descending colon. All 4 polyps were identified as red, pedunculated lesions. All 4 cases had no symptoms. In two cases, endoscopic findings of polyps were necessary to be differentiated from juvenile polyps.


CONCLUSIONS
Pedunculated lesions are the main pattern of IMGP. An analysis of endoscopic and histologic features in IMGP of the colorectum revealed that colonic IMGPs resembled juvenile polyps. On colonoscopy, IMGP should generally be taken into consideration as a differential diagnosis of peduncular polyp.
Hirasaki
Shoji
S
Division of Gastroenterology, Kubo Hospital, 1-1-19 Uchibori, Imabari 7992116, Japan. hirasaki@icknet.ne.jp
Kanzaki
Hiromitsu
H
Matsubara
Minoru
M
Suzuki
Seiyuu
S
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