title: Diagnosis of post-transplant lymphoproliferative disorder in solid organ transplant recipients - BCSH and BTS Guidelines.
abstract: A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Transplantation Society (BTS) has reviewed the available literature and made recommendations for the diagnosis and management of post-transplant lymphoproliferative disorder (PTLD) in adult recipients of solid organ transplants. This review details the risk factors predisposing to development, initial features and diagnosis. It is important that the risk of developing PTLD is considered when using post transplant immunosuppression and that the appropriate investigations are carried out when there are suspicions of the diagnosis. These must include tissue for histology and computed tomography scan to assess the extent of disease. These recommendations have been made primarily for adult patients, there have been some comments made with regard to paediatric practice.
authors.affiliation: The Beatson, West of Scotland Cancer Centre, Glasgow, UK. bcsh@b-s-h.org.uk
authors.forename: Anne
authors.initials: A
authors.lastname: Parker
authors.forename: Kristin
authors.initials: K
authors.lastname: Bowles
authors.forename: J Andrew
authors.initials: JA
authors.lastname: Bradley
authors.forename: Vincent
authors.initials: V
authors.lastname: Emery
authors.forename: Carrie
authors.initials: C
authors.lastname: Featherstone
authors.forename: Girish
authors.initials: G
authors.lastname: Gupte
authors.forename: Robert
authors.initials: R
authors.lastname: Marcus
authors.forename: Jayan
authors.initials: J
authors.lastname: Parameshwar
authors.forename: Alan
authors.initials: A
authors.lastname: Ramsay
authors.forename: Charles
authors.initials: C
authors.lastname: Newstead
mesh_terms: D020031:Epstein-Barr Virus Infections / Q000150:complications; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D016377:Organ Transplantation / Q000009:adverse effects*; D011159:Population Surveillance / Q000379:methods; D011182:Postoperative Care / Q000379:methods; D011300:Preoperative Care / Q000379:methods; D012307:Risk Factors