Cardiovascular aspects of sexual medicine.
BACKGROUND
Erectile dysfunction (ED) is common and considered to be predominantly of vascular origin.


OBJECTIVE
To evaluate the link between ED and coronary artery disease (CAD) and provide a consensus report regarding evaluation and management.


METHODS
A committee of eight experts from six countries was convened to review the worldwide literature concerning ED and CAD and provide a guideline for management.


METHODS
Expert opinion was based on grading the evidence-based medical literature, widespread internal committee discussion, public presentation, and debate.


RESULTS
ED and CAD frequently coexist. Between 50-70% of men with CAD have ED. ED can arise before CAD is symptomatic with a time window of 3-5 years. ED and CAD share the same risk factors, and endothelial dysfunction is the common denominator. Treating ED in cardiac patients is safe, provided that their risks are properly evaluated.


CONCLUSIONS
ED is a marker for silent CAD that needs to be excluded. Men with CAD frequently have ED that can be treated safely following guidelines.
Jackson
Graham
G
Guy's & St Thomas' Hospitals NHS Trust, Cardiology, London, UK. gjcardiol@talk21.com
Montorsi
Piero
P
Adams
Michael A
MA
Anis
Tarek
T
El-Sakka
Ahmed
A
Miner
Martin
M
Vlachopoulos
Charalambos
C
Kim
Edward
E
D015897:Comorbidity; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D048909:Diabetes Complications / Q000150:complications; D007172:Erectile Dysfunction / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D008019:Life Style; D008297:Male; D008511:Medicine / Q000379:methods / Q000592:standards; D024821:Metabolic Syndrome / Q000150:complications; D009765:Obesity / Q000150:complications; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D012307:Risk Factors; D044347:Sexology / Q000379:methods / Q000592:standards; D012907:Smoking / Q000009:adverse effects; D014572:Urology / Q000379:methods / Q000592:standards