Is nuclear deficiency of FoxO1 due to increased growth factor/PI3K/Akt-signalling in acne vulgaris reversed by isotretinoin treatment?
Melnik
B C
BC
D000152:Acne Vulgaris / Q000188:drug therapy / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D003879:Dermatologic Agents / Q000627:therapeutic use*; D051858:Forkhead Transcription Factors / Q000172:deficiency* / Q000378:metabolism; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism; D015474:Isotretinoin / Q000627:therapeutic use*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects; D015854:Up-Regulation
D003879:Dermatologic Agents; D051858:Forkhead Transcription Factors; D036341:Intercellular Signaling Peptides and Proteins; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt; D015474:Isotretinoin