Transition-metal-catalyzed synthesis of hydroxylated arenes.
An overview of the recent bibliography in the transition-metal-catalyzed hydroxylation of aryl derivatives is presented. Two reaction protocols are considered: 1) C--H activation/hydroxylation and, 2) cross-coupling hydroxylation of aryl halides. The achievements and limitations for both procedures are described taking into consideration different metal catalyst/oxidant combinations.
Alonso
Diego A
DA
Organic Chemistry Department and Institute for Organic Synthesis (ISO), Universidad de Alicante, Carretera de San Vicente s/n, Apdo. 99, 03080, Alicante, Spain. diego.alonso@ua.es
Nájera
Carmen
C
Pastor
Isidro M
IM
Yus
Miguel
M