title: Outcome of primary percutaneous intervention in patients with infarct-related coronary artery ectasia.
abstract: Data related to the incidence and clinical outcome of acute myocardial infarction (AMI) in patients with preexisting coronary artery ectasia (CAE) are limited. We assessed whether infarct-related artery ectasia (EIRA) indicates an untoward clinical outcome in patients with AMI undergoing primary percutaneous coronary intervention (pPCI). Consecutive patients (n = 643) who presented with AMI and were treated with pPCI were analyzed retrospectively; 31 patients (4.8%) had EIRA. Patients who had EIRA were significantly younger and had higher incidence of hypertension, previous stroke, smoking, inferior wall AMI, and Killip score >1. Infarct-related artery ectasia was more frequent in the right coronary artery (RCA). Impaired epicardial arterial flow, thrombus burden score of infarct-related artery (IRA), impaired Thrombolysis in Myocardial Infarction (TIMI) Myocardial Perfusion Grade, and distal embolization were significantly higher whereas ST-segment resolution and collateral vascular development were significantly lower in patients with EIRA. Infarct-related artery ectasia was an independent predictor of adverse outcome (odds ratio: 0.197; 95% confidence interval [CI]: 0.062-0.633; P = .006).
authors.affiliation: Department of Cardiology, Duzce University, Turkey. iserdemus@yahoo.com
authors.forename: Ismail
authors.initials: I
authors.lastname: Erden
authors.forename: Emine Cakcak
authors.initials: EC
authors.lastname: Erden
authors.forename: Hakan
authors.initials: H
authors.lastname: Ozhan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karabulut
authors.forename: Serkan
authors.initials: S
authors.lastname: Ordu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yazici
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D003331:Coronary Vessels / Q000503:physiopathology*; D004108:Dilatation, Pathologic / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000628:therapy*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors