Paliperidone use in the elderly.
Paliperidone, the active metabolite of risperidone is a relatively recent introduction for the treatment of schizophrenia. There is paucity of data regarding the use of paliperidone in elderly patients. We have attempted to highlight the prominent aspects of the use of paliperidone in the geriatric population. The limited data indicate that paliperidone may be effective and safe in the treatment of schizophrenia in the elderly.
Madhusoodanan
Subramoniam
S
Department of Psychiatry, St John's Episcopal Hospital, 327 Beach 19th Street, Far Rockaway, New York 11691, USA. sdanan@ehs.org
Zaveri
Deval
D
D000367:Age Factors; D000368:Aged; D002986:Clinical Trials as Topic / Q000379:methods; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D009422:Nervous System Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000378:metabolism; D000068882:Paliperidone Palmitate; D011743:Pyrimidines / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy* / Q000378:metabolism
D007555:Isoxazoles; D011743:Pyrimidines; D000068882:Paliperidone Palmitate