title: Efficient synthesis of alkyl aryl ketones & ketals via palladium-catalyzed regioselective arylation of vinyl ethers.
abstract: The combination of Pd(OAc)(2) with 1,3-bis(diphenylphosphino)propane (dppp) in ethylene glycol constitutes a high-performance catalytic system for highly regioselective arylation of a range of electron-rich vinyl ethers by aryl bromides to provide, upon hydrolysis, alkyl aryl ketones and cyclic ketals in good yields with up to 3.75 x 10(5) TON and 15625 h(-1) TOF.
authors.affiliation: Department of Chemistry, Renmin University of China, Beijing, 100872, China.
authors.forename: Mingcui
authors.initials: M
authors.lastname: Liu
authors.forename: Zeynab
authors.initials: Z
authors.lastname: Hyder
authors.forename: Yawei
authors.initials: Y
authors.lastname: Sun
authors.forename: Weijun
authors.initials: W
authors.lastname: Tang
authors.forename: Lijin
authors.initials: L
authors.lastname: Xu
authors.forename: Jianliang
authors.initials: J
authors.lastname: Xiao
mesh_terms: D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000085:Acetates; D007659:Ketones; D009942:Organometallic Compounds; D014753:Vinyl Compounds; C516071:palladium(II) acetate; C100195:vinyl ether