title: Cranioplasty for repair of a large bone defect with autologous and homologous bone in children.
abstract: Cranioplasty is a well-established reconstructive procedure for restoring craniocerebral protection and improving cosmetic defects. Most allograft materials are not suitable in pediatric patients owing to skull growth; thus, autologous bone is often preferred in the reconstruction of the pediatric skull because of its capacity to osseointegrate and grow with the pediatric skeleton. A 33-month-old boy with Ewing sarcoma of the right frontal bone underwent surgical treatment with tumor excision. The resected bone was reconstructed with full-thickness calvaria harvested from the right parietal region. The residual parietal gap was filled with homologous bone taken from the iliac wing. This reconstructive technique was chosen to guarantee normal development of the frontal region and tissue integration, while considering possible radiotherapy after the primary surgery.
authors.affiliation: Maxillo-Facial Surgery Operative Unit, Head and Neck Department, University and Hospital of Parma, Italy.
authors.forename: Bruno C
authors.initials: BC
authors.lastname: Brevi
authors.forename: Alice S
authors.initials: AS
authors.lastname: Magri
authors.forename: Livia
authors.initials: L
authors.lastname: Toma
authors.forename: Enrico
authors.initials: E
authors.lastname: Sesenna
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D002675:Child, Preschool; D003399:Craniotomy; D005624:Frontal Bone / Q000601:surgery*; D006801:Humans; D007085:Ilium / Q000637:transplantation; D008297:Male; D010294:Parietal Bone / Q000637:transplantation; D019651:Plastic Surgery Procedures / Q000379:methods*; D012512:Sarcoma, Ewing / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D012888:Skull Neoplasms / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
chemical_list: D001672:Biocompatible Materials