title: Factor analysis of behavioural symptoms in Huntington's disease.
abstract: A principal-components factor analysis was performed on behavioural data obtained from the European Huntington's Disease Network REGISTRY study. 1690 valid assessments using the United Huntington's Disease Rating Scale Behavioural Rating Scale were included in the analysis. This large data set confirmed previous reports of distinct behavioural patterns within Huntington's disease comprising a depressive factor, a dysexecutive factor, an irritability factor and a psychosis factor.
authors.affiliation: Department of Neuropsychiatry, Birmingham and Solihull Mental Health Foundation Trust, Barberry Building, 25 Vincent Drive, Edgbaston, Birmingham B15 2FG, UK. hugh.rickards@bsmhft.nhs.uk
authors.forename: Hugh
authors.initials: H
authors.lastname: Rickards
authors.forename: Jenny
authors.initials: J
authors.lastname: De Souza
authors.forename: Marleen
authors.initials: M
authors.lastname: van Walsem
authors.forename: Erik
authors.initials: E
authors.lastname: van Duijn
authors.forename: Sheila A
authors.initials: SA
authors.lastname: Simpson
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Squitieri
authors.forename: Bernhard
authors.initials: B
authors.lastname: Landwehrmeyer
mesh_terms: D001526:Behavioral Symptoms / Q000150:complications / Q000523:psychology*; D003863:Depression / Q000150:complications; D056344:Executive Function; D005163:Factor Analysis, Statistical; D006801:Humans; D006816:Huntington Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D007508:Irritable Mood; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications