title: Gastric mucosal changes caused by Lugol's iodine solution spray: endoscopic features of 64 cases on screening esophagogastroduodenoscopy.
abstract: OBJECTIVE
  To clarify the endoscopic mucosal change of the stomach caused by Lugol's iodine solution spray on screening esophagogastroduodenoscopy (EGD).
  
  
  METHODS
  Sixty-four consecutive patients who underwent EGD for esophageal squamous cell carcinoma screening were included in this study. The records for these patients included gastric mucosa findings before and after Lugol's iodine solution was sprayed. The endoscopic findings of the greater curvature of the gastric body were retrospectively analyzed based on the following findings: fold thickening, exudates, ulcers, and hemorrhage.
  
  
  RESULTS
  Mucosal changes occurred after Lugol's solution spray totally in 51 patients (80%). Fold thickening was observed in all 51 patients (80%), and a reticular pattern of white lines was found on the surface of the thickened gastric folds found in 28 of the patients (44%). Exudates were observed in 6 patients (9%).
  
  
  CONCLUSIONS
  The gastric mucosa could be affected by Lugol's iodine; the most frequent endoscopic finding of this effect is gastric fold thickening, which should not be misdiagnosed as a severe gastric disease.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, 812-8582 Higashi-ku Fukuoka City, Japan. tsuru-d@radiol.med.kyushu-u.ac.jp
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tsurumaru
authors.forename: Takashi
authors.initials: T
authors.lastname: Utsunomiya
authors.forename: Shuji
authors.initials: S
authors.lastname: Matsuura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Komori
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawanami
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Ishibashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
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