title: International position paper on febuxostat.
abstract: This position paper aims to clarify the presumed place of febuxostat in the management of gout patients. Since this novel xanthine oxidase inhibitor is now available, an international group of gout experts decided to formulate an international consensus statement. This statement presents the place for this new xanthine oxidase inhibitor in the treatment of gout which may contribute to optimize treatment of gout patients in Europe and worldwide.
authors.affiliation: Department of Rheumatology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands. t.jansen@znb.nl
authors.forename: Tim L
authors.initials: TL
authors.lastname: Jansen
authors.forename: Pascal
authors.initials: P
authors.lastname: Richette
authors.forename: Fernando
authors.initials: F
authors.lastname: Perez-Ruiz
authors.forename: Anne-Kathrin
authors.initials: AK
authors.lastname: Tausche
authors.forename: Philip-André
authors.initials: PA
authors.lastname: Guerne
authors.forename: Leonardo
authors.initials: L
authors.lastname: Punzi
authors.forename: Burkhard
authors.initials: B
authors.lastname: Leeb
authors.forename: Victoria
authors.initials: V
authors.lastname: Barskova
authors.forename: Till
authors.initials: T
authors.lastname: Uhlig
authors.forename: José
authors.initials: J
authors.lastname: Pimentão
authors.forename: Irena
authors.initials: I
authors.lastname: Zimmermann-Górska
authors.forename: Elisio
authors.initials: E
authors.lastname: Pascual
authors.forename: Thomas
authors.initials: T
authors.lastname: Bardin
authors.forename: Michael
authors.initials: M
authors.lastname: Doherty
mesh_terms: D000069465:Febuxostat; D006073:Gout / Q000188:drug therapy*; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D007391:International Cooperation; D013844:Thiazoles / Q000627:therapeutic use*; D016896:Treatment Outcome; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors
chemical_list: D006074:Gout Suppressants; D013844:Thiazoles; D000069465:Febuxostat; D014969:Xanthine Oxidase
references.citation: N Engl J Med. 2005 Dec 8;353(23):2450-61
references.pmid: 16339094
references.citation: Ann Rheum Dis. 2006 Oct;65(10):1312-24
references.pmid: 16707532
references.citation: Ann Rheum Dis. 2009 Jun;68(6):892-7
references.pmid: 18633127
references.citation: Ann Rheum Dis. 2009 Jan;68(1):51-6
references.pmid: 18250112
references.citation: Ann Rheum Dis. 2007 Oct;66(10):1269-70
references.pmid: 17881662
references.citation: Rheumatology (Oxford). 2009 May;48 Suppl 2:ii9-ii14
references.pmid: 19447780
references.citation: Rheumatology (Oxford). 2009 Feb;48(2):188-94
references.pmid: 19141576
references.citation: Arthritis Rheum. 2008 Nov 15;59(11):1540-8
references.pmid: 18975369
references.citation: Arthritis Rheum. 2005 Mar;52(3):916-23
references.pmid: 15751090
references.citation: Curr Opin Rheumatol. 2005 May;17(3):319-24
references.pmid: 15838244
references.citation: Rheumatology (Oxford). 2007 Aug;46(8):1372-4
references.pmid: 17522099
references.citation: Ann Rheum Dis. 2006 Oct;65(10):1301-11
references.pmid: 16707533