Heterochromatin, small RNA and post-fertilization dysgenesis in allopolyploid and interploid hybrids of Arabidopsis.
In many plants, including Arabidopsis, hybrids between species and subspecies encounter postfertilization barriers in which hybrid seed fail to develop, or else give rise to infertile progeny. In Arabidopsis, some of these barriers are sensitive to ploidy and to the epigenetic status of donor and recipient genomes. Recently, a role has been proposed for heterochromatin in reprogramming events that occur in reproductive cells, as well as in the embryo and endosperm after fertilization. 21 nt small interfering RNA (siRNA) from activated transposable elements accumulate in pollen, and are translocated from companion vegetative cells into the sperm, while in the maturing seed 24 nt siRNA are primarily maternal in origin. Thus maternal and paternal genomes likely contribute differing small RNA to the zygote and to the endosperm. As heterochromatic sequences also differ radically between, and within, species, small RNA sequences will diverge in hybrids. If transposable elements in the seed are not targeted by small RNA from the pollen, or vice versa, this could lead to hybrid seed failure, in a mechanism reminiscent of hybrid dysgenesis in Drosophila. Heterochromatin also plays a role in apomixis and nucleolar dominance, and may utilize a similar mechanism.
Martienssen
Robert A
RA
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. martiens@cshl.edu
D000818:Animals; D017360:Arabidopsis / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics; D044127:Epigenesis, Genetic; D005306:Fertilization / Q000235:genetics*; D020868:Gene Silencing; D018392:Genomic Imprinting / Q000235:genetics; D006570:Heterochromatin / Q000378:metabolism*; D006824:Hybridization, Genetic; D011123:Polyploidy; D034741:RNA, Small Interfering / Q000378:metabolism*
D006570:Heterochromatin; D034741:RNA, Small Interfering
Heredity (Edinb). 2009 Jan;102(1):24-30
18766201
Cell. 2006 Feb 10;124(3):495-506
16469697
Genetics. 2005 Aug;170(4):1979-88
15944363
Plant Cell. 2006 Apr;18(4):805-14
16531498
Mol Cell. 2008 Dec 26;32(6):753-4
19111654
Plant Cell. 2000 Sep;12(9):1551-68
11006331
Genes Dev. 2008 Jun 15;22(12):1567-71
18559472
Cold Spring Harb Symp Quant Biol. 2004;69:11-7
16117628
Cold Spring Harb Symp Quant Biol. 2008;73:265-71
19329575
Science. 2004 Jan 23;303(5657):521-3
14631047
Mol Genet Genomics. 2004 Oct;272(3):336-43
15372228
Curr Opin Plant Biol. 2007 Apr;10(2):116-22
17291819
Annu Rev Genomics Hum Genet. 2008;9:197-216
18767963
Curr Biol. 2003 Mar 4;13(5):421-6
12620192
Curr Biol. 2006 Jul 11;16(13):1322-8
16824920
Genes Dev. 2006 May 15;20(10):1283-93
16648464
Plant Cell. 2004 Dec;16(12):3174-80
15579806
Genes Dev. 2009 Sep 15;23(18):2124-33
19759261
Science. 1982 Jul 30;217(4558):446-8
17782980
Nat Rev Genet. 2007 May;8(5):382-93
17404584
PLoS Genet. 2005 Dec;1(6):e79
16389298
Science. 2006 Nov 24;314(5803):1292-5
17124320
Mol Cell. 2008 Dec 5;32(5):673-84
19061642
PLoS Biol. 2008 Aug 12;6(8):e194
18700816
Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11418-23
14504406
PLoS Biol. 2003 Dec;1(3):E67
14691539
Genetics. 2003 Jan;163(1):287-94
12586716
Biochim Biophys Acta. 2007 May-Jun;1769(5-6):383-92
17439825
Mol Genet Genomics. 2009 Apr;281(4):421-35
19148683
PLoS Biol. 2009 Oct;7(10):e1000234
19859525
PLoS One. 2008 May 28;3(5):e2298
18509545
PLoS Genet. 2009 Sep;5(9):e1000638
19730687
Genetics. 2008 Apr;178(4):1845-58
18430920
Plant Physiol. 2002 Jun;129(2):733-46
12068115
Curr Opin Plant Biol. 2009 Oct;12(5):637-42
19709923
Nature. 2004 Jul 22;430(6998):471-6
15269773
Nature. 2010 Mar 25;464(7288):628-32
20208518
PLoS Biol. 2007 Nov 6;5(11):e303
17988175
Chromosoma. 2009 Feb;118(1):37-41
18839198
Nat Genet. 2003 May;34(1):65-9
12669067
Plant Cell. 2005 Jan;17(1):52-60
15598800
Plant J. 2005 Jan;41(2):221-30
15634199
Nat Rev Genet. 2007 Apr;8(4):272-85
17363976
Plant Physiol. 2006 Nov;142(3):1160-8
17012404
PLoS Biol. 2008 Dec 9;6(12):2707-20
19071961
Nature. 2009 Jul 23;460(7254):473-8
19525931
Nature. 2009 Jul 9;460(7252):283-6
19494814
Genetics. 1999 Apr;151(4):1581-9
10101179
Trends Plant Sci. 2007 Aug;12(8):368-75
17629539
Nature. 2009 Sep 17;461(7262):427-30
19734882
Science. 1998 Apr 17;280(5362):446-50
9545225
Science. 2009 Jun 12;324(5933):1447-51
19520961
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17835-40
19805056
Cell. 2009 Feb 6;136(3):461-72
19203581
Adv Exp Med Biol. 2008;626:89-100
18372793
Dev Cell. 2003 Dec;5(6):891-901
14667411
Plant Physiol. 2003 Apr;131(4):1661-70
12692325
Science. 2008 Nov 28;322(5906):1387-92
19039138
Genetics. 2003 Jan;163(1):217-26
12586709
Plant Cell. 2003 Jun;15(6):1430-42
12782734
Curr Opin Genet Dev. 1998 Apr;8(2):240-4
9610416
Plant Cell. 2007 Jun;19(6):1782-94
17557811
Plant Cell. 2006 Jun;18(6):1360-72
16648367
PLoS Genet. 2009 Sep;5(9):e1000663
19779546
Cell. 2007 Feb 23;128(4):763-76
17320512
Biochim Biophys Acta. 2007 May-Jun;1769(5-6):422-8
17276527
Genes Genet Syst. 2007 Jun;82(3):177-86
17660688
Chromosome Res. 2006;14(1):71-82
16506097
Science. 2009 Mar 20;323(5921):1600-4
19179494
Plant J. 2008 Aug;55(4):596-606
18433438
PLoS One. 2007 Nov 07;2(11):e1157
17987131
Cell. 2009 May 1;137(3):522-35
19395010
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15965-70
16247000
Cell Stem Cell. 2009 Jun 5;4(6):493-8
19497276
Development. 2000 Jun;127(11):2493-502
10804189
Science. 2009 Jun 12;324(5933):1451-4
19520962
Annu Rev Genet. 2007;41:509-37
18076331