Laryngeal dedifferentiated liposarcoma.
BACKGROUND
Soft tissue liposarcomas are quite common in the adult population, whereas liposarcoma of the larynx is exceedingly rare.


METHODS
We describe an exceptional case of liposarcoma of the posterior aspect of the left arytenoid in a 62-year-old woman who was treated with two endoscopic excisions and adjuvant radiotherapy (RT). This is the 32nd case of laryngeal liposarcoma reported in the English literature.


RESULTS
After a 20 months follow-up, no local, regional recurrences or distant metastases were detected, and no functional complications are described for the patient.


CONCLUSIONS
This case report highlights that endoscopic surgical treatment enables excellent organ and functional preservation. However, recurrence of laryngeal liposarcoma is the principal risk, so extended follow-up is essential. RT has no defined role in treatment but can be discussed, especially considering the surgical margins and recurrence status.
Makeieff
Marc
M
Head and Neck Surgery Department, CHU Montpellier, Montpellier, France. m-makeieff@chu-montpellier.fr
Pelliccia
Pierfrancesco
P
Poizat
Flora
F
Arnaud
Sebastien
S
Rat
Florien
F
Cupissol
Didier
D
Guerrier
Bernard
B
Costes
Valérie
V
D014408:Biomarkers, Tumor / Q000032:analysis; D054337:Cell Dedifferentiation / Q000502:physiology*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D007821:Laryngeal Muscles / Q000473:pathology / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D007828:Laryngoscopy; D007830:Larynx / Q000473:pathology; D008080:Liposarcoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D008197:Lymph Node Excision; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D020266:Radiotherapy, Conformal; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor
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