Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors.
Rotili
Dante
D
Istituto Pasteur - Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Italy.
Tarantino
Domenico
D
Carafa
Vincenzo
V
Lara
Ester
E
Meade
Sarah
S
Botta
Giorgia
G
Nebbioso
Angela
A
Schemies
Jörg
J
Jung
Manfred
M
Kazantsev
Aleksey G
AG
Esteller
Manel
M
Fraga
Mario F
MF
Altucci
Lucia
L
Mai
Antonello
A
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells; D056572:Histone Deacetylase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D011744:Pyrimidinones / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D037761:Sirtuins / Q000037:antagonists & inhibitors* / Q000378:metabolism
D000970:Antineoplastic Agents; D056572:Histone Deacetylase Inhibitors; D011744:Pyrimidinones; D037761:Sirtuins