All-cause and CVD mortality in Native Hawaiians.
OBJECTIVE
Cardiovascular disease (CVD) is the leading cause of death among Native Hawaiians. In this article, all-cause and cardiovascular mortality rates among Native Hawaiians are examined, along with associated CVD risk factors.


METHODS
A total of 855 Native Hawaiians (343 men and 512 women, ages 19-88) were examined as participants of the Cardiovascular Risk Clinics program (1992-1998) and underwent surveillance through September 2007. Cause of each death was determined by review of medical records, death certificates, newspapers, and through queries to community members.


RESULTS
CVD accounted for 55% of deaths. Coronary heart disease (CHD) accounted for the majority of CVD deaths. CVD increased with age and was higher in those with diabetes, hypertension, or high low-density lipoprotein cholesterol (LDL-C). CVD rates were higher in men than in women and fourfold higher in those with diabetes. In addition to age, diabetes, hypertension, and elevated LDL-C were major risk factors.


CONCLUSIONS
Diabetes is a major determinant of CVD in this population and most of the CVD is occurring in those with diabetes. Strategies to prevent diabetes and manage blood pressure and lipids should reduce CVD rates in Native Hawaiians.
Aluli
N Emmett
NE
Moloka'i General Hospital, Kaunakakai, Moloka'i, HI, USA.
Reyes
Phillip W
PW
Brady
S Kalani
SK
Tsark
JoAnn U
JU
Jones
Kristina L
KL
Mau
Marjorie
M
Howard
Wm J
WJ
Howard
Barbara V
BV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000208:ethnology* / Q000401:mortality*; D003324:Coronary Artery Disease / Q000208:ethnology / Q000401:mortality; D003925:Diabetic Angiopathies / Q000208:ethnology* / Q000401:mortality*; D050171:Dyslipidemias / Q000208:ethnology / Q000401:mortality; D005260:Female; D006254:Hawaii / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000401:mortality; D008297:Male; D008875:Middle Aged; D044382:Population Groups / Q000706:statistics & numerical data*; D016016:Proportional Hazards Models; D012307:Risk Factors; D055815:Young Adult
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