title: [Acute and long-term treatment for bipolar depression].
abstract: Bipolar depression is linked with substantial burden and a high suicide risk, making a rapid and highly efficacious treatment mandatory. However, similar to mania, aspects of long-term treatment should already be considered at treatment initiation. With comparable efficacy, drugs with a beneficial safety and tolerability profile should be preferred. Additional psychotherapy can also noticeably improve both short- and long-term outcome of bipolar depression. Electroconvulsive therapy (ECT) still has its place in severe, treatment-resistant bipolar depression. Whereas ECT is a domain of specialised centres, correct diagnosis and both pharmacological and psychotherapeutic treatment initiation are essential tasks of primary care practitioners and secondary care psychiatrists.
authors.affiliation: Institute of Neuroscience, Psychiatry, Newcastle University, RVI, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK. Heinz.Grunze@ncl.ac.uk
authors.forename: H
authors.initials: H
authors.lastname: Grunze
authors.forename: S
authors.initials: S
authors.lastname: Dargel
mesh_terms: D000208:Acute Disease; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy*; D002908:Chronic Disease; D004565:Electroconvulsive Therapy / Q000639:trends*; D006801:Humans; D011613:Psychotherapy / Q000639:trends*
chemical_list: D000928:Antidepressive Agents
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