Does anesthetic provide similar neuroprotection to therapeutic hypothermia after cardiac arrest?
In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects after cardiac arrest. Further research in this area is warranted.
Zhang
Hong
H
Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, PR China. zhangh9@yahoo.com
D000777:Anesthetics / Q000494:pharmacology / Q000627:therapeutic use*; D006323:Heart Arrest / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced; D019636:Neurodegenerative Diseases / Q000517:prevention & control*
D000777:Anesthetics
Br J Anaesth. 2010 Feb;104(2):191-200
20086064
Acta Anaesthesiol Scand. 2007 Aug;51(7):893-9
17635397
Eur J Anaesthesiol. 2009 Nov;26(11):961-8
19687741
J Neurotrauma. 2009 Mar;26(3):371-6
19231920
PLoS One. 2009 Oct 26;4(10):e7588
19855846
Resuscitation. 2008 Nov;79(2):316-24
18621461
Crit Care. 2010;14(1):R21
20158893
Int J Mol Med. 2009 May;23(5):665-71
19360326
N Engl J Med. 2002 Feb 21;346(8):549-56
11856793
Anaesthesia. 2010 Mar;65(3):260-5
20085568
Resuscitation. 2010 May;81(5):603-8
20163907
Resuscitation. 2006 Nov;71(2):188-93
16987585
Resuscitation. 2005 Feb;64(2):181-6
15680527
Resuscitation. 2009 Feb;80(2):249-52
18954931
Anesthesiology. 2003 Jun;98(6):1315-27
12766638