title: Application of substrate curvature method to differentiate drying stresses in topical coatings and human stratum corneum.
abstract: Despite the extensive use of topical coatings in cosmetics, their effect on the mechanical properties of human skin and the perception of skin tightness in the form of drying stresses is not well understood. We describe the application of a recently developed substrate curvature technique to characterize stresses in drying and non-drying occlusive topical coatings. We then extend the technique to measure the combined effects of the coating applied to human stratum corneum (SC) where the overall drying stresses may have contributions from the coating, the SC and the interaction of the coating with the SC. We show how these separate contributions in the coating and SC layers can be differentiated.
authors.affiliation: Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, U.S.A.
authors.forename: K
authors.initials: K
authors.lastname: Levi
authors.forename: R H
authors.initials: RH
authors.lastname: Dauskardt
mesh_terms: D000287:Administration, Topical; D000368:Aged; D003358:Cosmetics / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006801:Humans; D012867:Skin / Q000378:metabolism*; D013500:Surface Tension; D014870:Water Loss, Insensible / Q000187:drug effects / Q000502:physiology*
chemical_list: D003358:Cosmetics