[RAAS inhibitors].
Acute coronary syndrome (ACS) is often associated with formation and development of atherosclerotic plaque, coronary artery vasoconstriction, rupture of vulnerable atherosclerotic plaque, coronary thrombus formation, and abrupt limitation of blood flow, leading to adverse outcomes. It is known that activation of the renin-angiotensin-aldosterone system(RAAS) contributes to aggravation of the condition. Thus, the RAAS inhibition is one of the therapeutic strategies of ACS. Considering the former evidence, ACE inhibitors and ARB are effective for prevention of ACS, respectively whereas ACE inhibitors would be slightly superior to ARB.
Minai
Kosuke
K
Department of Internal Medicine, The Jikei University School of Medicine.
Yoshimura
Michihiro
M
D054058:Acute Coronary Syndrome / Q000188:drug therapy*; D006801:Humans; D012084:Renin-Angiotensin System / Q000187:drug effects*