Asymmetric hydrogenation of ketones catalyzed by a ruthenium(II)-indan-ambox complex.
(S,R)-Indan-ambox ligand and its ruthenium(II) complex have been prepared and successfully applied to asymmetric hydrogenation of prochiral simple ketones. A wide range of unfunctionalized ketones are reduced by Ru(II)-indan-ambox catalyst with excellent enantioselectivities (up to 97% ee).
Li
Wei
W
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Hou
Guohua
G
Wang
Chunjiang
C
Jiang
Yutong
Y
Zhang
Xumu
X
D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D006865:Hydrogenation; D007189:Indans / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
D056831:Coordination Complexes; D007189:Indans; D007659:Ketones; D008024:Ligands; D012428:Ruthenium; C093582:indan