title: Effect of artrofoon on parameters of endogenous intoxication and activity of myeloperoxidase in leukocytes from patients with postoperative peritonitis.
abstract: We studied the possibility of using artrofoon in the treatment of patients with localized suppurative postoperative appendicular peritonitis. A significant inhibiting effect of the preparation on endogenous intoxication parameters was demonstrated. Inhibition of myeloperoxidase hyperactivity is considered as a possible mechanism of the therapeutic effect of artrofoon as a component of complex therapy.
authors.affiliation: Department of Urgent Medicine, Rostov State Medical University, Rostov-on-Don.
authors.forename: A V
authors.initials: AV
authors.lastname: Tarakanov
authors.forename: S L
authors.initials: SL
authors.lastname: Luspekyan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000097:blood / Q000188:drug therapy* / Q000201:enzymology*; D009195:Peroxidase / Q000097:blood / Q000378:metabolism*; D011184:Postoperative Period; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000911:Antibodies, Monoclonal; C503436:Artrofoon; D009195:Peroxidase