title: Inheritance of dermatoglyphic diversity in 500 Indian pedigrees: complex segregation analysis.
abstract: The main goal of the present communication is to determine the mode of inheritance of dermatoglyphic diversity traits through complex segregation analyses (genetic model fittings). The data consists of a large ethnically homogeneous sample of 500 Indian pedigrees (2435 individuals) of two generations. Principal component analysis, familial correlations and segregation analysis (package MAN-5) were used. A little genetic effect obtained from familial correlations but no evidence of major gene contribution found to be involved. By segregation analysis of the traits- PC 1_ Div, Div 9 and Div 11, both Mendelian and Environmental models were rejected (<<0.001) with the General model, i.e. despite the presence of significant inheritance (rejection of Environmental model), the nature of inheritance is more complex, than Mendelian model.
authors.affiliation: Biological Anthropology Unit, Indian Statistical Institute, Kolkata, India. bibha@isical.ac.in
authors.forename: Bibha
authors.initials: B
authors.lastname: Karmakar
authors.forename: Ika
authors.initials: I
authors.lastname: Malkin
authors.forename: Eugene
authors.initials: E
authors.lastname: Kobyliansky
mesh_terms: D020090:Chromosome Segregation / Q000235:genetics*; D003878:Dermatoglyphics / Q000145:classification*; D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D006801:Humans; D007194:India; D008297:Male; D057182:Mendelian Randomization Analysis; D008957:Models, Genetic; D010375:Pedigree; D019655:Quantitative Trait, Heritable; D012424:Rural Population; D012931:Social Environment; D044465:White People / Q000235:genetics*