Factor analysis of behavioural symptoms in Huntington's disease.
A principal-components factor analysis was performed on behavioural data obtained from the European Huntington's Disease Network REGISTRY study. 1690 valid assessments using the United Huntington's Disease Rating Scale Behavioural Rating Scale were included in the analysis. This large data set confirmed previous reports of distinct behavioural patterns within Huntington's disease comprising a depressive factor, a dysexecutive factor, an irritability factor and a psychosis factor.
Rickards
Hugh
H
Department of Neuropsychiatry, Birmingham and Solihull Mental Health Foundation Trust, Barberry Building, 25 Vincent Drive, Edgbaston, Birmingham B15 2FG, UK. hugh.rickards@bsmhft.nhs.uk
De Souza
Jenny
J
van Walsem
Marleen
M
van Duijn
Erik
E
Simpson
Sheila A
SA
Squitieri
Ferdinando
F
Landwehrmeyer
Bernhard
B
D001526:Behavioral Symptoms / Q000150:complications / Q000523:psychology*; D003863:Depression / Q000150:complications; D056344:Executive Function; D005163:Factor Analysis, Statistical; D006801:Humans; D006816:Huntington Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D007508:Irritable Mood; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications