title: [Course and treatment of myasthenia gravis during pregnancy].
abstract: Pregnancy and family planning issues are frequent concerns in the medical care of patients with myasthenia gravis since disease onset often coincides with the life period which is decisive in this respect. Although pregnancy, delivery and breastfeeding represent special circumstances in these patients, they are not associated with higher risks of complications compared to normal pregnancy, delivery and postpartum period. Frequently asked questions regard the course of pregnancy as well as the impact of the disease and particularly medical treatment on pregnancy and the foetus or neonate. Great significance is attached to the mode of delivery since it is still widely accepted that patients with myasthenia gravis have to deliver per elective caesarean section. This paper gives an overview and provides a basis for the medical care and individual counselling of patients with myasthenia gravis who want to start a family or are already pregnant.
authors.affiliation: Klinik für Neurologie, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. juliane.klehmet@charite.de
authors.forename: J
authors.initials: J
authors.lastname: Klehmet
authors.forename: J
authors.initials: J
authors.lastname: Dudenhausen
authors.forename: A
authors.initials: A
authors.lastname: Meisel
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001176:Arthrogryposis / Q000175:diagnosis; D001323:Autoantibodies / Q000097:blood; D001942:Breast Feeding; D002585:Cesarean Section; D002800:Cholinesterase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008274:Magnesium / Q000009:adverse effects / Q000627:therapeutic use; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D020941:Myasthenia Gravis, Neonatal / Q000175:diagnosis / Q000276:immunology; D009388:Neostigmine / Q000009:adverse effects / Q000627:therapeutic use; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D010353:Patient Education as Topic; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D011379:Prognosis; D011729:Pyridostigmine Bromide / Q000627:therapeutic use; D011950:Receptors, Cholinergic / Q000276:immunology; D012307:Risk Factors; D016216:Ultrasonography, Prenatal
chemical_list: D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D002800:Cholinesterase Inhibitors; D011950:Receptors, Cholinergic; D009388:Neostigmine; D008274:Magnesium; D011729:Pyridostigmine Bromide; D011241:Prednisone
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