title: Can exercise improve language and cognition in Parkinson's disease? A case report.
abstract: Parkinson's disease is commonly accompanied by cognitive issues that limit participation in activities of daily living. Unfortunately, most current treatment paradigms and pharmacotherapeutics fail to address the cognitive impairment demonstrated in this population. Mounting evidence in healthy older adults suggests that aerobic exercise may improve cognitive function. This article describes a patient with Parkinson's disease prescribed 8 weeks of aerobic exercise. Despite very high performance at baseline, the participant improved on several cognitive measures post exercise. The results of this investigation mimic the research in healthy older adults. We therefore suggest that future large scale randomized trials are warranted to evaluate the efficacy of aerobic exercise for ameliorating declines in cognitive performance in persons with PD.
authors.affiliation: Department of Neurology, University of Florida, Gainesville, FL 32611, USA. jnocera@ufl.edu
authors.forename: Joe R
authors.initials: JR
authors.lastname: Nocera
authors.forename: Lori J P
authors.initials: LJ
authors.lastname: Altmann
authors.forename: Christine
authors.initials: C
authors.lastname: Sapienza
authors.forename: Michael S
authors.initials: MS
authors.lastname: Okun
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Hass
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D003071:Cognition / Q000502:physiology*; D015444:Exercise; D005260:Female; D006801:Humans; D007802:Language; D010300:Parkinson Disease / Q000503:physiopathology* / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic