title: Primary diffuse leptomeningeal gliomatosis: report of a case presenting with chronic meningitis.
abstract: Neoplastic meningitis occurs in approximately 5% of patients with cancer. Primary diffuse leptomeningeal gliomatosis is a rare condition whereby a glioma arises from heterotopic cell nests in the leptomeninges. We report here a case presenting with clinical features similar to those of chronic infectious meningitis without positive cerebrospinal fluid cytology. Neurological signs in our patient deteriorated progressively without responding to antitubercular, antiviral, or antibiotic therapy. Leptomeningeal biopsy sampling revealed the condition to be primary diffuse leptomeningeal gliomatosis.
authors.affiliation: Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Sung-Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Dong-Chul
authors.initials: DC
authors.lastname: Jun
authors.forename: Jin Se
authors.initials: JS
authors.lastname: Park
authors.forename: Jae-Hyeok
authors.initials: JH
authors.lastname: Heo
authors.forename: Sung-Min
authors.initials: SM
authors.lastname: Kim
authors.forename: Juhan
authors.initials: J
authors.lastname: Kim
authors.forename: Sun Ha
authors.initials: SH
authors.lastname: Paek
authors.forename: Manho
authors.initials: M
authors.lastname: Kim
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