Serum phosphate level in burn patients.
BACKGROUND
Despite plasma phosphate imbalance being rare, it is a relatively common finding in certain subsets of burn patients. It may occur due to the burn itself or as a result of the treatment. Severe hypophosphataemia (<1.0 mg dl(-1)) is associated with a significant morbidity and a fourfold increase in mortality. In this study, the relation between serum phosphate level and the total body surface area (TBSA) of the burn was compared.


METHODS
According to the percentage of TBSA of the burn, the patients (n=155) were divided into three groups: group A with 20-29% TBSA burns, group B with 30-39% and group C with more than 40% TBSA burns (62, 48 and 45 patients, respectively). Analysis of variance (ANOVA)-repeated measure was used to detect any statistically significant difference in the three post-burn time-points of 3rd, 6th and 9th days and the mean score of the serum phosphate level between the three groups.


RESULTS
The incidence of hypophosphataemia at 9th post-burn day in the three groups was 6.1%, 32.4% and 73.5%, respectively. There were significant differences (p<0.05) between mean serum phosphate levels of groups A and C, B and C and A and B as well. We found significant differences between the three post-burn follow-up time stages.


CONCLUSIONS
We have shown that hypophosphataemia, defined as mean serum phosphate levels below 3.0 mg dl(-1), was very common following burn, based on 75.6% of patients with more than 40% burn at the 3rd post-burn day. As the percentage of TBSA of burn increases, the incidence of hypophosphataemia significantly increases. We suggest that phosphate level be routinely measured after a major burn, especially in patients with a complicated course, so that appropriate replacement therapy may be started in a timely manner.
Loghmani
Shahriar
S
Department of Plastic Surgery, Imam Musa-Kazem Burn Hospital, Isfahan University of Medical Sciences, Kaveh Street, Isfahan, Iran. sh_loghmani@yahoo.com
Maracy
Mohammad Reza
MR
Kheirmand
Reza
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002056:Burns / Q000097:blood* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D017674:Hypophosphatemia / Q000453:epidemiology*; D015994:Incidence; D007223:Infant; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood*; D013997:Time Factors; D055815:Young Adult
D010710:Phosphates