title: Typical carcinoids and neuroendocrine carcinomas of the stomach: differing clinical courses and prognoses.
abstract: BACKGROUND
  Gastric endocrine tumors are usually classified as 3 types of well-differentiated endocrine tumors (typical carcinoids or carcinoids) and poorly differentiated carcinomas (neuroendocrine carcinomas [NECs]).
  
  
  METHODS
  From 1993 to 2008, 97 patients (73 men and 24 women) were diagnosed with gastric neuroendocrine tumors at the Asan Medical Center.
  
  
  RESULTS
  Of the 45 patients with typical carcinoids, 37 underwent surgery (eg, endoscopic resection). Of the 52 patients with NECs, 43 underwent surgery (eg, radical gastrectomy). One patient died of recurrence of the typical carcinoids, whereas 26 patients with NECs died of related diseases (P < .05). The rates of survival and recurrence did not significantly differ by type of typical carcinoid (P > .05).
  
  
  CONCLUSIONS
  Regardless of the type, carcinoids that are not yet advanced can be effectively treated with minimal endoscopic or laparoscopic surgery. However, all NECs and advanced carcinoids should be treated with radical gastrectomy.
authors.affiliation: Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea. bskim@amc.seoul.r
authors.forename: Beom Su
authors.initials: BS
authors.lastname: Kim
authors.forename: Sung Tae
authors.initials: ST
authors.lastname: Oh
authors.forename: Jeong Hwan
authors.initials: JH
authors.lastname: Yook
authors.forename: Kab Choong
authors.initials: KC
authors.lastname: Kim
authors.forename: Min Gyu
authors.initials: MG
authors.lastname: Kim
authors.forename: Jun Won
authors.initials: JW
authors.lastname: Jeong
authors.forename: Byung Sik
authors.initials: BS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018278:Carcinoma, Neuroendocrine / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018450:Disease Progression; D005260:Female; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome