Src may be involved in the anti-cancer effect of conjugated linoleic acid. Comment on: CLA reduces breast cancer cell growth and invasion through ER and PI3K/Akt pathways.
Chen
Jiezhong
J
D000970:Antineoplastic Agents / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D047628:Estrogen Receptor alpha / Q000378:metabolism; D005260:Female; D006801:Humans; D044243:Linoleic Acids, Conjugated / Q000494:pharmacology*; D020935:MAP Kinase Signaling System / Q000187:drug effects; D009361:Neoplasm Invasiveness / Q000517:prevention & control; D047495:PPAR gamma / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D013002:Somatomedins / Q000378:metabolism; D019061:src-Family Kinases / Q000378:metabolism*
D000970:Antineoplastic Agents; D047628:Estrogen Receptor alpha; D044243:Linoleic Acids, Conjugated; D047495:PPAR gamma; D013002:Somatomedins; D019869:Phosphatidylinositol 3-Kinases; D019061:src-Family Kinases; D051057:Proto-Oncogene Proteins c-akt