title: Microbial metabolism. Part 11. Metabolites of flutamide.
abstract: The yeast culture, Rhodotorula mucilaginosa (ATCC 20129) transformed flutamide (1) to three metabolites: 4-nitro-3-(trifluoromethyl)aniline (2), 2-methyl-N-[4-amino-3-(trifloromethyl)phenyl]propanamide (3) and N-[4-amino-3-(trifluoromethyl)phenyl]acetamide (4). The structures were established by spectroscopic methods.
authors.affiliation: National Center for Natural Products Research, The University of Mississippi, University, MS 38677, USA.
authors.forename: Wimal
authors.initials: W
authors.lastname: Herath
authors.forename: Ikhlas Ahmad
authors.initials: IA
authors.lastname: Khan
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000737:chemistry / Q000378:metabolism*; D005485:Flutamide / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D015394:Molecular Structure; D012248:Rhodotorula / Q000737:chemistry / Q000378:metabolism*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D005485:Flutamide