title: Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial.
abstract: BACKGROUND
  If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS(R) gives an eightfold concentrate platelets of patients own blood. Injection of these platelets in the attachment of the fascia to the os calcis might induce a healing rate.
  
  
  METHODS
  A randomized controlled multi centre trial will be performed. The study population consists of 120 patients of 18 years and older. Patients with chronic plantar fasciitis will be allocated randomly to have a steroid injection or an autologous platelet concentrate injections. Data will be collected before the procedure, 4,8,12,26 weeks and 1 year after the procedure.The main outcome measures of this study are pain and function measured with questionnaires.
  
  
  CONCLUSIONS
  Recent literature show positive effects for the treatment of tendinosis with autologous platelet injections. The forthcoming trial will compare treatment for chronic plantar fasciitis with a steroid injection versus an autologous platelet injection. Our results will be published as soon as they become available.
  
  
  BACKGROUND
  
  
  
  BACKGROUND
  http://www.clinicaltrials.gov NCT00758641.
authors.affiliation: Department of Orthopaedics, Elisabeth Ziekenhuis Tilburg, The Netherlands.
authors.forename: Joost C
authors.initials: JC
authors.lastname: Peerbooms
authors.forename: Wilbert
authors.initials: W
authors.lastname: van Laar
authors.forename: Frank
authors.initials: F
authors.lastname: Faber
authors.forename: Hans M
authors.initials: HM
authors.lastname: Schuller
authors.forename: Henk
authors.initials: H
authors.lastname: van der Hoeven
authors.forename: Taco
authors.initials: T
authors.lastname: Gosens
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage; D002985:Clinical Protocols; D002986:Clinical Trials as Topic / Q000379:methods; D004185:Disability Evaluation; D036981:Fasciitis, Plantar / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D009426:Netherlands; D017063:Outcome Assessment, Health Care / Q000379:methods; D010147:Pain Measurement / Q000379:methods; D017060:Patient Satisfaction; D017713:Platelet Transfusion / Q000379:methods*; D053657:Platelet-Rich Plasma / Q000502:physiology*; D011788:Quality of Life; D012107:Research Design; D011795:Surveys and Questionnaires; D014182:Transplantation, Autologous / Q000379:methods; D014945:Wound Healing / Q000502:physiology*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D000779:Anesthetics, Local
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