title: Absence of mutations in GJB2 (Connexin-26) gene in an ethnic group of southwest Iran.
abstract: BACKGROUND
  The common GJB2 gene mutation (35delG) has been previously reported from Iranian patients that were affected with nonsyndromic autosomal recessive deafness. We, therefore, for the first time, investigated the prevalence and frequency of the GJB2 gene mutation in the Iranian deaf population with Arabian origins.
  
  
  METHODS
  We amplified and sequenced the entire coding sequence of the GJB2 gene from 61 deaf patients and 26 control subjects.
  
  
  RESULTS
  None of the analyzed samples revealed deafness-associated mutation.
  
  
  CONCLUSIONS
  This finding differs from several reports from Iran as we have focused on the GJB2 gene that possesses various mutations as the cause of congenital recessive deafness.
authors.affiliation: Department of Genetics, Faculty of Science, Chamran University, Ahwaz, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Galehdari
authors.forename: Ali Mohammad
authors.initials: AM
authors.lastname: Foroughmand
authors.forename: Maryam Naderi
authors.initials: MN
authors.lastname: Soorki
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Mohammadian
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