title: Impact of interim methadone maintenance on HIV risk behaviors.
abstract: The extent to which interim methadone (IM) without counseling reduces HIV risk behavior has not been reported. The AIDS Risk Assessment scale was administered at baseline and 4-month follow-up to 319 adult heroin-dependent participants randomly assigned to IM or waiting list. On an intent-to-treat basis, there was a significantly greater reduction in drug injection and unprotected sex while high from baseline to follow-up, favoring the IM condition. Remedying the shortage of methadone capacity through the expansion of IM would be a worthwhile approach to reducing the spread of HIV infection.
authors.affiliation: Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA. mwilson@friendsresearch.org
authors.forename: Monique E
authors.initials: ME
authors.lastname: Wilson
authors.forename: Robert P
authors.initials: RP
authors.lastname: Schwartz
authors.forename: Kevin E
authors.initials: KE
authors.lastname: O'Grady
authors.forename: Jerome H
authors.initials: JH
authors.lastname: Jaffe
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009294:Narcotics / Q000627:therapeutic use*; D012309:Risk-Taking; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000534:rehabilitation*
chemical_list: D009294:Narcotics; D008691:Methadone
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