Screening and management of anal dysplasia and anal cancer in HIV-infected patients: a guide for practice.
People living with HIV infection have a significantly higher rate of anal cancer as compared with that of uninfected people. It is believed that high-grade anal dysplasia secondary to human papillomavirus infection is a precursor to anal cancer. Considering this, screening and treatment of high-grade anal dysplasia is a possible means of preventing the development of anal cancer. No national or international guidelines exist to guide practice for screening and management of anal dysplasia. On the basis of a review of research and expert recommendations, a guide to practice for screening and management of anal dysplasia and anal cancer is made for clinicians.
Moran
Matt G
MG
AIDS Healthcare Foundation, Hollywood Clinic, Los Angeles, CA, USA.
Barkley
Thomas W
TW
Hughes
Cynthia B
CB
D001005:Anus Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male