title: Is there an impatience genotype leading to non-adherence to long-term therapies?
abstract: In chronic diseases such as diabetes, adherence to therapy aims to preserve health, which is a long-term objective, whereas non-adherence tends to present an immediate 'reward'. We propose that non-adherence, like addiction, is at least in part due to the fact that, for physiological, and maybe genetic reasons described in a new field, neuroeconomics, a number of people have a taste for the present rather than the future. Thus, for 'impatient patients' it is natural not to adhere to therapeutic prescriptions that share the characteristic of being future-oriented. This hypothesis may apply to any disease requiring long-term therapy.
authors.affiliation: Service d'Endocrinologie, Diabétologie, Maladies Métaboliques, Hôpital Avicenne APHP, 125 route de Stalingrad, 93000 Bobigny, France. gerard.reach@avc.aphp.fr
authors.forename: G
authors.initials: G
authors.lastname: Reach
mesh_terms: D006801:Humans; D055118:Medication Adherence / Q000523:psychology*; D013997:Time Factors; D016903:Drug Monitoring
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