title: Adapting a Vacuum Assisted Closure dressing to challenging wounds: negative pressure treatment for perineal necrotizing fasciitis with rectal prolapse in a newborn affected by acute myeloid leukaemia.
abstract: We report the case of a newborn with acute myeloid leukaemia, who developed perineal necrotizing fasciitis due to Pseudomonas Aeruginosa, after twenty days of life. Following surgical debridement, she was effectively treated with topical negative pressure therapy (V.A.C.(R) device) with silver foam dressings, this achieved complete closure in thirteen days. Negative pressure therapy should be considered when conventional wound care fails to achieve complete wound closure, even in neonates.
authors.affiliation: Unit of Plastic Surgery, S.Orsola-Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy. luca.negosanti81@gmail.com
authors.forename: Luca
authors.initials: L
authors.lastname: Negosanti
authors.forename: Arianna
authors.initials: A
authors.lastname: Aceti
authors.forename: Tommaso
authors.initials: T
authors.lastname: Bianchi
authors.forename: Luigi
authors.initials: L
authors.lastname: Corvaglia
authors.forename: Francesca
authors.initials: F
authors.lastname: Negosanti
authors.forename: Rossella
authors.initials: R
authors.lastname: Sgarzani
authors.forename: Paolo Giovanni
authors.initials: PG
authors.lastname: Morselli
authors.forename: Riccardo
authors.initials: R
authors.lastname: Cipriani
authors.forename: Massimino
authors.initials: M
authors.lastname: Negosanti
authors.forename: Annalisa
authors.initials: A
authors.lastname: Patrizi
authors.forename: Giacomo
authors.initials: G
authors.lastname: Faldella
mesh_terms: D001458:Bandages; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D010502:Perineum; D011552:Pseudomonas Infections / Q000382:microbiology / Q000628:therapy*; D012005:Rectal Prolapse / Q000382:microbiology / Q000628:therapy*; D014618:Vacuum; D014945:Wound Healing