title: MDCT findings of denim-sandblasting-induced silicosis: a cross-sectional study.
abstract: BACKGROUND
  Denim sandblasting is as a novel cause of silicosis in Turkey, with reports of a recent increase in cases and fatal outcomes. We aimed to describe the radiological features of patients exposed to silica during denim sandblasting and define factors related to the development of silicosis.
  
  
  METHODS
  Sixty consecutive men with a history of exposure to silica during denim sandblasting were recruited. All CT examinations were performed using a 64-row multi-detector CT (MDCT). The nodules were qualitatively and semi-quantitatively analyzed by grading nodular profusion (NP) on CT images.
  
  
  RESULTS
  Silicosis was diagnosed radiologically in 73.3% of patients (44 of 60). The latency period (the time between initial exposure and radiological imaging) and duration of silica exposure was longer in patients diagnosed with silicosis than in those without silicosis (p < 0.05). Nodules were present in all cases with centrilobular type as the commonest (63.6%). All cases of silicosis were clinically classified as accelerated and 11.4% had progressive massive fibrosis (PMF). Mild NP lesions were the most prevalent in all six zones of the lung. The NP score was significantly correlated with the duration of silica exposure, the latency period, presence of PMF, and pleural thickening. Enlarged lymphadenopathy was present in 45.5% of patients.
  
  
  CONCLUSIONS
  The duration of exposure and the latency period are important for development of silicosis in denim sandblasters. MDCT is a useful tool in detecting findings of silicosis in workers who has silica exposure.
authors.affiliation: Dicle University School of Medicine Department of Radiology 21280, Diyarbakir, Turkey. cihanakgul@gmail.com
authors.forename: Cihan Akgul
authors.initials: CA
authors.lastname: Ozmen
authors.forename: Hasan
authors.initials: H
authors.lastname: Nazaroglu
authors.forename: Tekin
authors.initials: T
authors.lastname: Yildiz
authors.forename: Aylin Hasanefendioglu
authors.initials: AH
authors.lastname: Bayrak
authors.forename: Senem
authors.initials: S
authors.lastname: Senturk
authors.forename: Gungor
authors.initials: G
authors.lastname: Ates
authors.forename: Levent
authors.initials: L
authors.lastname: Akyildiz
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects*; D012829:Silicosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult
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