title: Acute appendicitis--open or minimally-invasive approach?
abstract: BACKGROUND
  Although laparoscopy has become the standard approach in other procedures, this technique is not generally accepted for acute appendicitis.
  
  
  OBJECTIVE
  To evaluate the results after minimally invasive appendectomies.
  
  
  METHODS
  All medical records of patients operated for acute appendicitis during the last year were retrospectively reviewed. We considered only patients with diagnosis of acute appendicitis confirmed by histopathology. We designed two groups: operated by open approach (OA) and operated by minimally-invasive approach (MIA). The two groups were compared for differenced in homogeneity and main end results: morbidity, mortality, hospital stay.
  
  
  RESULTS
  The men/women ratio was 112/88 (1.27), with a mean age of 31.83 +/- 1.06 years. There were more women in the MIA and more men in the OA group, p = 0.001. The Alvarado score was significant lower in MIA group (5.69 +/- 0.24 versus 6.57 +/- 0.23, p = 0.009). Comorbidities were noted in 51% from the patients, most of them in MIA group: 58.8%; N = 60, p = 0.016. Mean operation time was similar in both groups: 36.96 +/- 1.48 in OA versus 37.03 +/- 1.39 minutes in MIA. The postoperative mortality rate was 0.5%. The postoperative morbidity rate was 12%. Even though the number of cases with postoperative complications were double in OA group (16 cases versus 8 cases in MIA group) it did not reach statistical significance, p = 0.073. Histopathological examinations revealed early acute appendicitis in 45.5% cases (N = 91), suppurative appendicitis in 46.5% (N = 93) and gangrenous appendicitis in 8% (N = 16); early acute appendicitis was more frequent in MIA group and suppurative appendicitis in OA group: p = 0.017. The hospital stay was similar in both groups: 4.34 +/- 0.39 in OA versus 3.58 +/- 0.25 days in MIA group; p = 0.103.
  
  
  CONCLUSIONS
  MIA is a safe procedure and can be performed even in the patients with comorbidities. We didn't find any statistical significant difference from point of view of postoperative morbidity; however more postoperative complications were find in OA vs MIA group. The postoperative hospital stay was similar in both groups.
authors.affiliation: First Surgical Unit, "St. Spiridon" Hospital, "Gr. T. Popa" University of Medicine and Pharmacy, Iaşi, Romania. moldovar@iasi.mednet.ro
authors.forename: R
authors.initials: R
authors.lastname: Moldovanu
authors.forename: N
authors.initials: N
authors.lastname: Vlad
authors.forename: E
authors.initials: E
authors.lastname: Târcoveanu
authors.forename: G
authors.initials: G
authors.lastname: Dimofte
authors.forename: C
authors.initials: C
authors.lastname: Lupaşcu
authors.forename: V
authors.initials: V
authors.lastname: Filip
authors.forename: C
authors.initials: C
authors.lastname: Bradea
authors.forename: G
authors.initials: G
authors.lastname: Răileanu
authors.forename: B
authors.initials: B
authors.lastname: Tuţuianu
authors.forename: F
authors.initials: F
authors.lastname: Crumpei
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001062:Appendectomy / Q000379:methods*; D001064:Appendicitis / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D012720:Severity of Illness Index; D016019:Survival Analysis