title: Comparative animal study on hard tissue integration and bone formation of different Nobel Biocare implants.
abstract: Dental implantation aims at optimal and long-term hard tissue integration. Beside primary stability, loading time and other factors, e.g. the surface of the endosteal part of the implant, is a matter of special importance. In this animal trial, hard tissue integration of two different implant types was studied using radiological, histological and histomorphometric analysis. Two different implants with an oxidized surface (TiUnite; Nobel Biocare AB, Goteborg, Sweden, NobelReplace Tapered Groovy 4.3 x 10 mm and Replace Select Tapered 4.3 x 10 mm) were inserted into the right and left mandibles of 10 German domestic pigs between canine and premolar and immediately provided with a ceramic crown. The primary implant stability was determined using resonance frequency analysis. After 70 days, the test animals were killed and specimens were collected for histological and histomorphometric examination. All implants showed good primary stability after surgery. Histological and histomorphometrical analysis revealed no significant differences in the bone apposition. The immediate loading of the different implant types don't have any negative effects on the bone apposition in the period of 70 days. The long-term effects of immediate loading of these types of implant requires further studies.
authors.affiliation: Department of Orthodontics, Preventive and Pediatric Dentistry, Ernst-Moritz-Arndt University Greifswald, Germany. gedrange@uni-greifswald.de
authors.forename: T
authors.initials: T
authors.lastname: Gedrange
authors.forename: T
authors.initials: T
authors.lastname: Gredes
authors.forename: M
authors.initials: M
authors.lastname: Gredes
authors.forename: M R F
authors.initials: MR
authors.lastname: Allegrini
authors.forename: G
authors.initials: G
authors.lastname: Borsos
authors.forename: A
authors.initials: A
authors.lastname: Vegh
authors.forename: M B
authors.initials: MB
authors.lastname: Salles
authors.forename: F
authors.initials: F
authors.lastname: Heinemann
authors.forename: M
authors.initials: M
authors.lastname: Dominiak
authors.forename: S
authors.initials: S
authors.lastname: Allegrini
mesh_terms: D000818:Animals; D003758:Dental Implantation, Endosseous / Q000295:instrumentation* / Q000592:standards; D015921:Dental Implants / Q000592:standards; D017268:Dental Prosthesis Retention / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D008334:Mandible / Q000000981:diagnostic imaging / Q000601:surgery* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D010012:Osteogenesis / Q000502:physiology*; D011859:Radiography; D011897:Random Allocation; D034421:Sus scrofa; D014025:Titanium / Q000592:standards
chemical_list: D015921:Dental Implants; D014025:Titanium