Silver catalyzed cascade synthesis of alkaloid ring systems: concise total synthesis of fascaplysin, homofascaplysin C and analogues.
A silver catalyzed and microwave assisted one-pot cascade synthesis provides efficient access to diverse alkaloid-inspired scaffold classes, and a concise and efficient total synthesis of homofascaplysin C and fascaplysin.
Waldmann
Herbert
H
Max Planck Institut für molekulare Physiologie, Otto-Hahn Strasse 11, 44227-Dortmund, Germany. Herbert.Waldmann@mpi-dortmund.mpg.de
Eberhardt
Luc
L
Wittstein
Kathrin
K
Kumar
Kamal
K
D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism; D000644:Quaternary Ammonium Compounds; D002243:Carbolines; D007212:Indolizines
D007211:Indoles; D009942:Organometallic Compounds; D012834:Silver; C551976:homofascaplysin C; C069346:fascaplysine; D000644:Quaternary Ammonium Compounds; D002243:Carbolines; D007212:Indolizines