title: Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation.
abstract: OBJECTIVE
  To report a case of necrotizing scleritis after pterygium surgery with conjunctival autografting (CA) and intraoperative Mitomycin C (MMC) and its treatment with amniotic membrane transplantation (AMT) and systemic steroid.
  
  
  METHODS
  A 41-year-old woman who had recurrent nasal pterygium underwent pterygium excision with CA and intraoperative MMC. Two weeks after surgery, graft necrosis and necrotizing scleritis associated with severe pain and irritation were observed on her operated eye.
  
  
  RESULTS
  Pulse steroid treatment (intravenous 1 g methylprednisolone for 3 days) was initiated and AMT was performed for ocular surface reconstruction. Over the next 2 weeks, the graft vascularization was complete and there was no complication which required further treatment.
  
  
  CONCLUSIONS
  Necrotizing scleritis is a rare complication of CA with MMC. Systemic steroid therapy is necessary for subsiding ocular inflammation and AMT can be performed for ocular surface reconstruction.
authors.affiliation: Department of Ophthalmology, Baskent University School of Medicine, Ankara, Turkey. akaralezli@yahoo.com
authors.forename: Aylin
authors.initials: A
authors.lastname: Karalezli
authors.forename: Cem
authors.initials: C
authors.lastname: Kucukerdonmez
authors.forename: Mehmet
authors.initials: M
authors.lastname: Borazan
authors.forename: Yonca A
authors.initials: YA
authors.lastname: Akova
mesh_terms: D000328:Adult; D000650:Amnion / Q000637:transplantation*; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage; D016685:Mitomycin / Q000008:administration & dosage; D011183:Postoperative Complications; D011379:Prognosis; D011625:Pterygium / Q000601:surgery*; D020551:Pulse Therapy, Drug; D012008:Recurrence; D015423:Scleritis / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D014182:Transplantation, Autologous
chemical_list: D016685:Mitomycin; D008775:Methylprednisolone