Emerging techniques in stratified designs and continuous gradients for tissue engineering of interfaces.
Interfacial tissue engineering is an emerging branch of regenerative medicine, where engineers are faced with developing methods for the repair of one or many functional tissue systems simultaneously. Early and recent solutions for complex tissue formation have utilized stratified designs, where scaffold formulations are segregated into two or more layers, with discrete changes in physical or chemical properties, mimicking a corresponding number of interfacing tissue types. This method has brought forth promising results, along with a myriad of regenerative techniques. The latest designs, however, are employing "continuous gradients" in properties, where there is no discrete segregation between scaffold layers. This review compares the methods and applications of recent stratified approaches to emerging continuously graded methods.
Dormer
Nathan H
NH
Bioengineering Program, University of Kansas, Lawrence, KS 66045, USA.
Berkland
Cory J
CJ
Detamore
Michael S
MS
D001672:Biocompatible Materials / Q000138:chemical synthesis*; D017076:Computer-Aided Design / Q000639:trends*; D004867:Equipment Design; D005544:Forecasting; D013499:Surface Properties; D023822:Tissue Engineering / Q000639:trends*
D001672:Biocompatible Materials
Biomaterials. 2008 Oct;29(30):4065-73
18649939
Tissue Eng Part A. 2010 May;16(5):1737-47
20038201
Biomaterials. 2010 Mar;31(8):2313-22
19969346
Pharm Res. 2007 Feb;24(2):258-64
17191092
Acta Biomater. 2009 Feb;5(2):661-9
18990616
Trends Biotechnol. 2008 Jul;26(7):382-92
18501452
Biomaterials. 2009 Mar;30(7):1428-39
19081131
Biomaterials. 2010 Jan;31(3):461-6
19819008
J Biomed Mater Res A. 2010 Mar 1;92(3):913-21
19291683
Biomaterials. 2010 May;31(15):4313-21
20188414
Acta Biomater. 2010 Mar;6(3):892-9
19766743
IEEE Eng Med Biol Mag. 2008 Sep-Oct;27(5):109-13
18799400
Biomaterials. 2008 Jul;29(20):2962-8
18433863
Injury. 2010 Jul;41(7):693-701
20035935
Biomaterials. 2008 Sep;29(26):3539-46
18538387
J Biomed Mater Res B Appl Biomater. 2009 Jan;88(1):254-63
18698625
Langmuir. 2008 Mar 18;24(6):2294-317
18220435
J Control Release. 2009 Jan 5;133(1):37-43
18838089
Tissue Eng Part B Rev. 2009 Mar;15(1):55-73
19207035
Ann Biomed Eng. 2010 Jun;38(6):2167-82
20379780
Tissue Eng. 2006 Dec;12(12):3497-508
17518686
J Mater Sci Mater Med. 2007 Dec;18(12):2251-6
17562138
Tissue Eng Part C Methods. 2008 Dec;14(4):299-309
18795865
Acta Biomater. 2009 Jan;5(1):374-80
18706880
Osteoarthritis Cartilage. 2008 Sep;16(9):1083-91
18378169
Acta Biomater. 2010 Feb;6(2):455-65
19616135
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12170-5
18719120
Biomaterials. 2000 Dec;21(24):2529-43
11071603
Adv Drug Deliv Rev. 2008 Jan 14;60(2):243-62
17976858
Trends Biotechnol. 2008 Apr;26(4):181-9
18299159
J Control Release. 2009 Mar 4;134(2):81-90
19071168
Tissue Eng Part B Rev. 2008 Mar;14(1):61-86
18454635
Tissue Eng. 2006 Dec;12(12):3307-39
17518671
J Biomed Mater Res A. 2010 Sep 1;94(3):870-6
20336753
J Biomed Mater Res A. 2010 Jul;94(1):112-21
20128006
Biomaterials. 2009 Apr;30(10):1898-909
19157536
J Biomater Appl. 2010 May;24(8):693-712
19451181
Biomaterials. 2009 Mar;30(8):1587-95
19108884
Int J Pharm. 2009 Jun 5;374(1-2):90-5
19446764
J Mater Sci Mater Med. 2007 Feb;18(2):201-9
17323151
Acta Biomater. 2010 Apr;6(4):1569-74
19896564
Tissue Eng Part B Rev. 2008 Dec;14(4):341-66
18803499
Nat Biotechnol. 2001 Nov;19(11):1029-34
11689847
Tissue Eng Part A. 2010 May;16(5):1469-77
20001254
Int J Pharm. 2009 Aug 13;378(1-2):108-15
19501149
Comb Chem High Throughput Screen. 2009 Jul;12(6):589-97
19601756
Clin Oral Implants Res. 2009 Mar;20(3):240-6
19397635
Biomed Mater. 2007 Dec;2(4):224-32
18458479
J Mech Behav Biomed Mater. 2008 Apr;1(2):140-52
19627779
Tissue Eng Part A. 2009 Nov;15(11):3321-9
19385724
J Biomater Sci Polym Ed. 2009;20(3):399-409
19192363
J Cell Physiol. 2000 Aug;184(2):207-13
10867645
Adv Biochem Eng Biotechnol. 2006;102:91-111
17089787
Clin Sports Med. 2009 Jan;28(1):157-76
19064172
Semin Cell Dev Biol. 2009 Aug;20(6):665-73
19146967
Tissue Eng Part B Rev. 2009 Jun;15(2):127-41
19231983
J Biomater Sci Polym Ed. 2010;21(3):289-302
20178686
J Biomed Mater Res B Appl Biomater. 2009 Oct;91(1):213-20
19422050
Tissue Eng Part B Rev. 2009 Jun;15(2):143-57
19203206
J Orthop Res. 2007 Dec;25(12):1609-20
17676622
Biomaterials. 2010 May;31(14):3903-9
20170957
J Biomed Mater Res A. 2008 Jul;86(1):1-12
18442111
Biomaterials. 2009 Jul;30(21):3542-50
19339047
J Biomed Mater Res B Appl Biomater. 2009 Apr;89(1):135-47
18780360
J Biomech. 2007;40(4):750-65
16730354
J Biomed Mater Res B Appl Biomater. 2009 Jul;90(1):275-82
19086057
Tissue Eng Part A. 2010 Apr;16(4):1123-41
19863255
Ann Biomed Eng. 2004 Jan;32(1):148-59
14964730
Tissue Eng Part B Rev. 2008 Dec;14(4):447-64
18844605