title: Microwave-induced synthesis of schiff bases of aminothiazolyl bromocoumarins as antibacterials.
abstract: A fast and highly efficient method for the synthesis of some of the schiff bases of aminothiazolylbromocoumarin (4a-m) has been performed by microwave irradiation of 2'-amino-4'-(6-bromo-3-coumarinyl) thiazole (3) and substituted aromatic aldehydes (a-m). Microwave assisted reactions have resulted in better yields of the desired products than when prepared under conventional conditions. The resulting products were evaluated for their qualitative and quantitative antibacterial activity.
authors.affiliation: Department of Pharmaceutical Chemistry, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Hosur Road, Bangalore - 560 027, India.
authors.forename: K N
authors.initials: KN
authors.lastname: Venugopala
authors.forename: B S
authors.initials: BS
authors.lastname: Jayashree
references.citation: J Med Chem. 1992 Jul 24;35(15):2735-43
references.pmid: 1379639
references.citation: Acta Virol. 1993 Aug;37(4):241-50
references.pmid: 7905238
references.citation: Antimicrob Agents Chemother. 1993 Oct;37(10):2200-5
references.pmid: 8257145