title: Functional reorganization induced by endovascular embolization of a cerebral AVM.
abstract: We mapped motor function in a patient with a cerebral arteriovenous malformation (AVM) before and after treatment with endovascular embolization. Functional activation using technetium-99m-hexamethylpropyleneamine single photon emission tomography (99mTc-HMPAO-SPECT) demonstrated a redistribution of regional cerebral blood flow (rCBF) that correlated with clinical improvement. Intravascular feeding artery pressure measurements, serial angiography, and challenge with a pharmacological vasodilator enabled us to explore possible mechanisms of functional reorganization.
authors.affiliation: Department of Neurology, Neurological Institute, Columbia-Presbyterian Medical Center, New York, New York 10032, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Marshall
authors.forename: L
authors.initials: L
authors.lastname: Hacein-Bey
authors.forename: W L
authors.initials: WL
authors.lastname: Young
authors.forename: J
authors.initials: J
authors.lastname: Pile-Spellman
authors.forename: S
authors.initials: S
authors.lastname: Das
authors.forename: G
authors.initials: G
authors.lastname: Perera
authors.forename: J P
authors.initials: JP
authors.lastname: Mohr