Mechanisms of odor-tracking: multiple sensors for enhanced perception and behavior.
Early in evolution, the ability to sense and respond to changing environments must have provided a critical survival advantage to living organisms. From bacteria and worms to flies and vertebrates, sophisticated mechanisms have evolved to enhance odor detection and localization. Here, we review several modes of chemotaxis. We further consider the relevance of a striking and recurrent motif in the organization of invertebrate and vertebrate sensory systems, namely the existence of two symmetrical olfactory sensors. By combining our current knowledge about the olfactory circuits of larval and adult Drosophila, we examine the molecular and neural mechanisms underlying robust olfactory perception and extend these analyses to recent behavioral studies addressing the relevance and function of bilateral olfactory input for gradient detection. Finally, using a comparative theoretical approach based on Braitenberg's vehicles, we speculate about the relationships between anatomy, circuit architecture and stereotypical orientation behaviors.
Gomez-Marin
Alex
A
EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation, Universitat Pompeu Fabra Barcelona, Spain.
Duistermars
Brian J
BJ
Frye
Mark A
MA
Louis
Matthieu
M
Biochimie. 1998 Feb;80(2):129-35
9587670
Cell. 1999 Mar 5;96(5):725-36
10089887
Trends Neurosci. 1997 Jun;20(6):245-52
9185305
Behav Genet. 1989 Mar;19(2):267-83
2497723
J Exp Biol. 2006 Aug;209(Pt 15):3001-17
16857884
J Exp Biol. 2009 Jul;212(Pt 13):1973-9
19525421
Curr Biol. 2005 Jun 7;15(11):982-92
15936268
Proc Biol Sci. 2009 Oct 7;276(1672):3413-20
19586944
Nat Neurosci. 2008 Aug;11(8):874-6
18641642
J Neurosci. 2007 Oct 31;27(44):11966-77
17978037
PLoS Comput Biol. 2008 Apr 25;4(4):e1000028
18389066
Science. 2004 Jan 16;303(5656):366-70
14684826
Nat Neurosci. 2007 May;10(5):623-30
17417635
Science. 2005 Jun 24;308(5730):1931-4
15976304
Cell. 2003 Jan 24;112(2):271-82
12553914
Neuron. 2007 Jan 4;53(1):103-15
17196534
Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11352-7
19541615
Nature. 2008 Apr 24;452(7190):956-60
18344978
Nature. 2007 Jan 25;445(7126):406-9
17251974
Eur J Neurosci. 2008 Aug;28(4):675-92
18702690
J Neurosci. 2009 Jul 1;29(26):8595-603
19571150
Neuron. 2002 Oct 24;36(3):463-74
12408848
Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19027-32
16357192
J Neurosci. 1999 Nov 1;19(21):9557-69
10531458
Curr Biol. 2008 Aug 5;18(15):1153-5
18674910
J Neurosci. 2008 Sep 24;28(39):9710-22
18815257
Neuron. 2008 Jul 10;59(1):110-24
18614033
Annu Rev Neurosci. 2006;29:163-201
16776583
Biophys J. 1977 Nov;20(2):193-219
911982
Commun Integr Biol. 2010 Jan;3(1):60-3
20539786
Curr Biol. 2009 Aug 25;19(16):R700-13
19706282
Cell. 2009 Jan 9;136(1):149-62
19135896
Cell. 1991 Apr 5;65(1):175-87
1840504
Adv Exp Med Biol. 2008;628:102-14
18683641
Nature. 2007 Mar 29;446(7135):542-6
17392786
Genetics. 1990 Feb;124(2):293-302
2106470
Genes Dev. 2005 Feb 15;19(4):419-24
15681611
Nature. 2007 Sep 27;449(7161):468-72
17873857
Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10314-9
19502424
Front Cell Neurosci. 2010 Mar 16;4:1
20407584
Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1421-5
14718671
Nat Neurosci. 2007 Jan;10(1):27-9
17173046
J Neurogenet. 1985 Feb;2(1):1-30
4020527
Nature. 2008 Mar 27;452(7186):473-7
18305480
Nature. 1972 Oct 27;239(5374):500-4
4563019
Curr Biol. 2005 Sep 6;15(17):1535-47
16139208
Curr Biol. 2004 Mar 23;14(6):449-57
15043809
J Comp Neurol. 2002 Apr 15;445(4):374-87
11920714
Nat Neurosci. 2009 Sep;12(9):1136-44
19684589
Genes Brain Behav. 2004 Jun;3(3):127-37
15140008
Curr Biol. 2005 Sep 6;15(17):1548-53
16139209
J Vis Exp. 2008 Jan 03;(11):
19066557
Science. 1937 Apr 30;85(2209):430-1
17814221
Z Zellforsch Mikrosk Anat. 1972;131(1):109-40
5073638
J Insect Physiol. 2000 Feb;46(2):135-144
12770245
Learn Mem. 1998 May-Jun;5(1-2):52-77
10454372
Chem Senses. 2007 Jan;32(1):65-89
17071942
Microsc Res Tech. 2001 Dec 1;55(5):284-96
11754508
Cell. 2006 Apr 7;125(1):143-60
16615896
Annu Rev Neurosci. 2007;30:505-33
17506643
Nature. 2009 Sep 10;461(7261):277-81
19710651
Cell. 2004 Jun 25;117(7):965-79
15210116
Curr Biol. 2002 Oct 29;12(21):1877-84
12419190
Nature. 2008 Apr 24;452(7190):1007-11
18408711
Neuron. 2003 Jul 3;39(1):147-61
12848939
Curr Opin Neurobiol. 2004 Dec;14(6):737-44
15582377
J Biol. 2009;8(1):9
19171076
Acta Physiol Pharmacol Bulg. 1999;24(4):91-100
11098295
Nat Neurosci. 2010 Mar;13(3):393-9
20154683
J Comp Neurol. 2008 Jun 10;508(5):711-55
18395827
Curr Biol. 2009 Aug 11;19(15):1301-7
19576769
Cell. 2007 Mar 23;128(6):1187-203
17382886
Cell. 2005 Jun 3;121(5):795-807
15935765
Arthropod Struct Dev. 2000 Jul;29(3):211-29
18088928
J Neurosci. 2005 Oct 5;25(40):9069-79
16207866
Nature. 2004 Oct 14;431(7010):854-9
15372051
Cell. 2007 Feb 9;128(3):601-12
17289577
Nat Neurosci. 2008 Feb;11(2):187-99
18157126
Neuron. 2004 Sep 2;43(5):703-14
15339651
Brain Res. 1988 Jun 21;453(1-2):299-307
3135918
Biol Bull. 2000 Apr;198(2):203-12
10786941
Neuron. 2005 May 5;46(3):445-56
15882644
J Neurogenet. 2009;23(1-2):173-84
19145515
Science. 1979 Oct 5;206(4414):93-6
17812455
Curr Biol. 2005 Dec 6;15(23):2086-96
16332533
J Comp Neurol. 1999 Mar 22;405(4):543-52
10098944
J Neurogenet. 2009;23(4):366-77
19863268
PLoS One. 2007 Apr 04;2(4):e354
17406678
Cell. 1999 Mar 5;96(5):713-23
10089886
PLoS Biol. 2006 Feb;4(2):e20
16402857
Neuron. 2007 Apr 5;54(1):89-103
17408580
Nature. 2009 May 14;459(7244):218-23
19396157
J Neurosci. 1999 Aug 1;19(15):6599-609
10414987
Front Zool. 2009 Feb 27;6:5
19250516
J Exp Biol. 2006 Jul;209(Pt 14):2739-48
16809465
Chem Senses. 2006 Feb;31(2):93-105
16339271
Cell. 2002 Apr 19;109(2):243-55
12007410
Curr Biol. 2007 Apr 3;17(7):599-605
17363250
J Exp Biol. 2000 Oct;203(Pt 19):2977-90
10976034
Nat Neurosci. 2007 Nov;10(11):1474-82
17922008
J Exp Biol. 2004 Jan;207(Pt 1):123-31
14638839
Curr Biol. 2006 Jan 10;16(1):101-9
16401429
Science. 2006 Feb 3;311(5761):666-70
16456082
J Exp Biol. 2003 Mar;206(Pt 5):843-55
12547939
Science. 2000 Apr 28;288(5466):672-5
10784450
Curr Biol. 2008 Feb 26;18(4):270-5
18280156
Nature. 2008 Apr 24;452(7190):1002-6
18408712
Cell Tissue Res. 1990 Oct;262(1):9-34
2124174
Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10040-5
16006514
Mol Biol Evol. 2008 Jun;25(6):1081-92
18296696
J Biol Chem. 2007 Jan 12;282(2):1216-24
17114180
Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15336-41
11742061
Proc Biol Sci. 1992 May 22;248(1322):103-9
1352888
J Neurophysiol. 2008 Feb;99(2):734-46
18094099
Neuron. 2008 May 8;58(3):401-13
18466750
J Exp Biol. 2006 Jan;209(Pt 1):32-42
16354776
Neuron. 2008 Oct 23;60(2):328-42
18957224
Science. 1969 Dec 26;166(3913):1588-97
4902679