[Perioperative beta-receptor blockade. For and against].
Results from recent studies have questioned the application of beta-receptor blockers for reduction of morbidity and mortality during the perioperative period. This holds true especially for patients with no or only low cardiac risk. Although beta-receptor blockade was a form of standard therapy at the end of the 1990s, data today show no clear evidence for such a therapy not even in patients at risk for cardiac events. At least in patients with low risk the initiation of beta-receptor blockade during the perioperative period might lead to side-effects, thereby increasing morbidity and mortality.
Preckel
B
B
Department of Anesthesiology, Academic Medical Centre AMC, University of Amsterdam, Meibergdreef 9, 1100 Amsterdam, The Netherlands. b.preckel@amc.uva.nl
Poels
M
M
Wappler
F
F
Schlack
W
W
Buhre
W
W
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D006331:Heart Diseases / Q000150:complications; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D009203:Myocardial Infarction / Q000517:prevention & control; D019990:Perioperative Care / Q000401:mortality; D011183:Postoperative Complications / Q000139:chemically induced / Q000401:mortality; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D018570:Risk Assessment
D000319:Adrenergic beta-Antagonists
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