title: Circaseptan variation in case-fatality rate for patients with acute subarachnoid hemorrhage (Takashima Stroke Registry 1988-2003).
abstract: We explored the circaseptan variation in 28-day case-fatalities for patients with subarachnoid hemorrhage (SAH) across days of the week. Data were obtained from the Takashima Stroke Registry, which covers approximately 50000 residents of central Japan. There were 169 first-ever SAH cases registered during the period 1988-2003 (68 in males, 101 in females). We divided the SAH cases into two groups according to the day on which the SAH occurred: "weekend" and "weekday". The 28-day case-fatality rate and 95% confidence interval (CI) were calculated. Multiple logistic regression analysis was used to calculate the adjusted odds ratio (95% CI) for weekday fatalities by entering all relevant patient-level variables into the model. The 28-day case-fatality rate for SAH was higher on weekdays (51.7%) than on weekends (32.6%; odds ratio 2.19; 95% CI: 1.10-4.49). The differences in fatality rate persisted after adjustment for age, sex, severity, family history of stroke and patient history of hypertension, diabetes mellitus, dyslipidemia, drinking and smoking. We observed a circaseptan variation in fatalities from SAH, with higher fatality rates during weekdays in our study population.
authors.affiliation: Department of Health Science, Shiga University of Medical Science, Otsu City, Shiga, Japan. turin@belle.shiga-med.ac.jp
authors.forename: Tanvir Chowdhury
authors.initials: TC
authors.lastname: Turin
authors.forename: Yoshikuni
authors.initials: Y
authors.lastname: Kita
authors.forename: Nahid
authors.initials: N
authors.lastname: Rumana
authors.forename: Nayouki
authors.initials: N
authors.lastname: Takashima
authors.forename: Masaharu
authors.initials: M
authors.lastname: Ichikawa
authors.forename: Hideki
authors.initials: H
authors.lastname: Sugihara
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Morita
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Hirose
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Miura
authors.forename: Akira
authors.initials: A
authors.lastname: Okayama
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Ueshima
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002909:Chronobiology Phenomena / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012042:Registries; D020521:Stroke / Q000150:complications / Q000401:mortality* / Q000503:physiopathology; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000401:mortality* / Q000503:physiopathology; D015996:Survival Rate / Q000639:trends