title: Psychosocial treatment for methamphetamine use disorders: a preliminary randomized controlled trial of cognitive behavior therapy and Acceptance and Commitment Therapy.
abstract: Acceptance and Commitment Therapy (ACT) incorporates developments in behavior therapy, holds promise but has not been evaluated for methamphetamine use disorders. The objective of this study was to test whether ACT would increase treatment attendance and reduce methamphetamine use and related harms compared to cognitive behavior therapy (CBT). One hundred and four treatment-seeking adults with methamphetamine abuse or dependence were randomly assigned to receive 12 weekly 60-minute individual sessions of ACT or CBT. Attrition was 70% at 12 weeks and 86% at 24 weeks postentry. Per intention-to-treat analysis, there were no significant differences between the treatment groups in treatment attendance (median 3 sessions), and methamphetamine-related outcomes; however, methamphetamine use (toxicology-assessed and self-reported), negative consequences, and dependence severity significantly improved over time in both groups. Although ACT did not improve treatment outcomes or attendance compared to CBT, it may be a viable alternative to CBT for methamphetamine use disorders. Future rigorous research in this area seems warranted.
authors.affiliation: Centre for Treatment of Anxiety Disorders, Thebarton, South Australia, Australia. matthew.smout@health.sa.gov.au
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Smout
authors.forename: Marie
authors.initials: M
authors.lastname: Longo
authors.forename: Sonia
authors.initials: S
authors.lastname: Harrison
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Minniti
authors.forename: Wendy
authors.initials: W
authors.lastname: Wickes
authors.forename: Jason M
authors.initials: JM
authors.lastname: White
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019969:Amphetamine-Related Disorders / Q000628:therapy*; D001242:Assertiveness; D001521:Behavior Therapy / Q000379:methods*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006197:Hair / Q000737:chemistry; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000032:analysis; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data
chemical_list: D008694:Methamphetamine