title: Simulation-based evaluation and optimization of a new CdZnTe gamma-camera architecture (HiSens).
abstract: A new gamma-camera architecture named HiSens is presented and evaluated. It consists of a parallel hole collimator, a pixelated CdZnTe (CZT) detector associated with specific electronics for 3D localization and dedicated reconstruction algorithms. To gain in efficiency, a high aperture collimator is used. The spatial resolution is preserved thanks to accurate 3D localization of the interactions inside the detector based on a fine sampling of the CZT detector and on the depth of interaction information. The performance of this architecture is characterized using Monte Carlo simulations in both planar and tomographic modes. Detective quantum efficiency (DQE) computations are then used to optimize the collimator aperture. In planar mode, the simulations show that the fine CZT detector pixelization increases the system sensitivity by 2 compared to a standard Anger camera without loss in spatial resolution. These results are then validated against experimental data. In SPECT, Monte Carlo simulations confirm the merits of the HiSens architecture observed in planar imaging.
authors.affiliation: CEA, LETI, MINATEC, F38054 Grenoble, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Robert
authors.forename: Guillaume
authors.initials: G
authors.lastname: Montémont
authors.forename: Véronique
authors.initials: V
authors.lastname: Rebuffel
authors.forename: Irène
authors.initials: I
authors.lastname: Buvat
authors.forename: Lucie
authors.initials: L
authors.lastname: Guérin
authors.forename: Loïck
authors.initials: L
authors.lastname: Verger
mesh_terms: D002104:Cadmium; D015902:Gamma Cameras; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D013691:Tellurium; D015899:Tomography, Emission-Computed, Single-Photon; D015032:Zinc
chemical_list: C474490:CdZnTe; D002104:Cadmium; D015032:Zinc; D013691:Tellurium