title: [Results of surgical treatment of locally-spread colorectal cancer].
abstract: During the period from 2001 to 2005 operations were performed on 186 patients with locally-spread colorectal cancer. In 132 cases (the 1st group) radical combined resections were performed, 54 patients (the 2nd group) underwent palliative operations. The morbidity rate was 18.2% (24 cases) in the first group and 7.4% (4 cases) in the second group. The mortality rate in the first group was 2.3% (3 cases), no mortality was observed in the second group. Overall 3-year survival in the first group was 69.9%, and no one patient of the second group survived longer than 3 years. Overall 5-year survival in the first group was 54.7%, and the relapse-free 5-year survival was 52.8%. The data obtained have shown the effectiveness of combined resections in treatment of locally-spread colorectal cancer. We suggest that further improvement of long-term results can be achieved using chemoradiation.
authors.forename: E A
authors.initials: EA
authors.lastname: Nadvikova
authors.forename: K V
authors.initials: KV
authors.lastname: Semikopov
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D002430:Cecal Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D003082:Colectomy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D012811:Sigmoid Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D016896:Treatment Outcome