Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation.
OBJECTIVE
To report a case of necrotizing scleritis after pterygium surgery with conjunctival autografting (CA) and intraoperative Mitomycin C (MMC) and its treatment with amniotic membrane transplantation (AMT) and systemic steroid.


METHODS
A 41-year-old woman who had recurrent nasal pterygium underwent pterygium excision with CA and intraoperative MMC. Two weeks after surgery, graft necrosis and necrotizing scleritis associated with severe pain and irritation were observed on her operated eye.


RESULTS
Pulse steroid treatment (intravenous 1 g methylprednisolone for 3 days) was initiated and AMT was performed for ocular surface reconstruction. Over the next 2 weeks, the graft vascularization was complete and there was no complication which required further treatment.


CONCLUSIONS
Necrotizing scleritis is a rare complication of CA with MMC. Systemic steroid therapy is necessary for subsiding ocular inflammation and AMT can be performed for ocular surface reconstruction.
Karalezli
Aylin
A
Department of Ophthalmology, Baskent University School of Medicine, Ankara, Turkey. akaralezli@yahoo.com
Kucukerdonmez
Cem
C
Borazan
Mehmet
M
Akova
Yonca A
YA
D000328:Adult; D000650:Amnion / Q000637:transplantation*; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage; D016685:Mitomycin / Q000008:administration & dosage; D011183:Postoperative Complications; D011379:Prognosis; D011625:Pterygium / Q000601:surgery*; D020551:Pulse Therapy, Drug; D012008:Recurrence; D015423:Scleritis / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D014182:Transplantation, Autologous
D016685:Mitomycin; D008775:Methylprednisolone