title: Biotin interaction with human erythrocytes: contact on membrane surface and formation of self-assembled fibrous structures.
abstract: The binding of biotin to human erythrocytes (red blood cells, RBCs) is followed with the help of optical and atomic force microscopy methods. As certain biotin derivatives gain access to Plasmodium falciparum infected erythrocytes and block parasite-induced transport of other solutes, the microscopy observations reported in this communication will provide impetus to unravel the access mechanism of biotin and its derivatives to malaria infected erythrocytes.
authors.affiliation: Department of Chemistry, Indian Institute of Technology-Kanpur, Kanpur-208016 (UP), India.
authors.forename: K B
authors.initials: KB
authors.lastname: Joshi
authors.forename: V
authors.initials: V
authors.lastname: Venkatesh
authors.forename: Sandeep
authors.initials: S
authors.lastname: Verma
mesh_terms: D001710:Biotin / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D018625:Microscopy, Atomic Force; D010963:Plasmodium falciparum / Q000502:physiology
chemical_list: D001710:Biotin