title: Hepatic spleen nodules (HSN).
abstract: Hepatic splenosis is a nodular implant of normal spleen tissue in the liver. This innocent liver nodule is frequently misinterpreted as a malignancy. Almost all hepatic splenoses have been associated with a clinical history of splenic trauma or prior surgery. This report describes two cases of hepatic splenosis. In both patients, the nodular lesions were initially thought to be liver malignancies and they were ultimately assessed by histology. The clinico-pathological findings of all published cases of liver splenosis underwent critical review. Although they are rare, hepatic spleen nodules should always be included in the diagnostic spectrum of nodular liver lesions because of their impact on treatment decisions.
authors.affiliation: Department of Pathology, University of Padova, Padova, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Mescoli
authors.forename: Carlo
authors.initials: C
authors.lastname: Castoro
authors.forename: Adriana
authors.initials: A
authors.lastname: Sergio
authors.forename: Alberto
authors.initials: A
authors.lastname: Ruol
authors.forename: Fabio
authors.initials: F
authors.lastname: Farinati
authors.forename: Massimo
authors.initials: M
authors.lastname: Rugge
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000601:surgery; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000601:surgery; D016629:Esophagectomy; D005260:Female; D006801:Humans; D008099:Liver; D008297:Male; D008875:Middle Aged; D017890:Splenosis / Q000175:diagnosis* / Q000473:pathology