title: Fatalistic responses to different types of genetic risk information: exploring the role of self-malleability.
abstract: Providing people with genetic risk information may induce a sense of fatalism, the belief that little can be done to reduce the risk. We postulated that fatalism is a function of health risk information and individual differences in self-perception. DNA-based risk information was hypothesised to generate more fatalism than risk information based on family history or non-genetic risk information. Moreover, people who view themselves as more rather than less able to change self-attributes were hypothesised to respond least fatalistically. Factor analyses in separate samples were used to construct a five-item 'Malleability of self' measure. Predictive validity of the measure was tested using a within-subjects analogue design. Participants responded to three scenario vignettes in which they were informed of an increased risk of cardiovascular disease (CVD). In Scenario 1, risk was ascertained by DNA testing, family history and cholesterol testing; in Scenario 2, it was ascertained by family history and cholesterol testing; in Scenario 3, risk was ascertained by cholesterol testing alone. Scenario 1 was associated with least perceived control over cholesterol level and CVD risk. People who viewed themselves as more able to change self-attributes experienced more control in all three scenarios.
authors.affiliation: Department of Public and Occupational Health, EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands. liesbeth.claassen@vumc.nl
authors.forename: Liesbeth
authors.initials: L
authors.lastname: Claassen
authors.forename: Lidewij
authors.initials: L
authors.lastname: Henneman
authors.forename: Riekie
authors.initials: R
authors.lastname: De Vet
authors.forename: Dirk
authors.initials: D
authors.lastname: Knol
authors.forename: Theresa
authors.initials: T
authors.lastname: Marteau
authors.forename: Danielle
authors.initials: D
authors.lastname: Timmermans
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001294:Attitude to Health; D005260:Female; D020022:Genetic Predisposition to Disease / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D020377:Self Efficacy; D011795:Surveys and Questionnaires; D014342:Truth Disclosure; D055815:Young Adult