A new fixation strategy for addressable nano-network building blocks.
Rapid controlled self-assembly makes DNA ideal for building nanostructures. A problem using hybridized intermediates in hierarchic assembly is their thermodynamic lability. We demonstrate a click-fixation technology by which robust hexagonal DNA modules can be made. This principle is applicable to a wide variety of DNA nanoconstructs.
Lundberg
Erik P
EP
Department of Chemical and Biological Engineering/Physical Chemistry, Chalmers University of Technology, Kemivägen 10, SE-412 96 Gothenburg, Sweden.
El-Sagheer
Afaf H
AH
Kocalka
Petr
P
Wilhelmsson
L Marcus
LM
Brown
Tom
T
Nordén
Bengt
B
D004247:DNA / Q000737:chemistry*; D004591:Electrophoresis, Polyacrylamide Gel; D031541:Fluorescence Resonance Energy Transfer; D049329:Nanostructures / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry
D009841:Oligonucleotides; D004247:DNA