Effect of artrofoon on parameters of endogenous intoxication and activity of myeloperoxidase in leukocytes from patients with postoperative peritonitis.
We studied the possibility of using artrofoon in the treatment of patients with localized suppurative postoperative appendicular peritonitis. A significant inhibiting effect of the preparation on endogenous intoxication parameters was demonstrated. Inhibition of myeloperoxidase hyperactivity is considered as a possible mechanism of the therapeutic effect of artrofoon as a component of complex therapy.
Tarakanov
A V
AV
Department of Urgent Medicine, Rostov State Medical University, Rostov-on-Don.
Luspekyan
S L
SL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000097:blood / Q000188:drug therapy* / Q000201:enzymology*; D009195:Peroxidase / Q000097:blood / Q000378:metabolism*; D011184:Postoperative Period; D016896:Treatment Outcome; D055815:Young Adult
D000911:Antibodies, Monoclonal; C503436:Artrofoon; D009195:Peroxidase