title: Quantitative comparison of ginsenosides and polyacetylenes in wild and cultivated American ginseng.
abstract: Quantitative comparison of seven ginsenosides in wild and cultivated American ginseng revealed that the Rg(1)/Rd ratio presented a significantly large difference between cultivated and type-I (one of the defined chemotypes) wild American ginseng, facilitating this ratio as a characteristic marker for differentiating these two groups. Similarly, the ratio (Rg(1)+Re)/Rd, and the ratio of protopanaxatriol (PPT)-type ginsenosides to protopanaxadiol (PPD)-type ginsenosides showed a large difference between these two groups. On the other hand, type-II wild samples were found to have high Rg(1)/Rb(1) and Rg(1)/Re ratios and low panaxydol/panaxynol ratio, which is entirely different from Type-I American ginseng, but is very similar to that of Asian ginseng. This not only suggests that the chemotype should be taken into consideration properly when using these parameters for differentiating American and Asian ginseng, but also indicates that type-II wild American ginseng may have distinct pharmacological activities and therapeutic effects.
authors.affiliation: School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
authors.forename: Jing-Rong
authors.initials: JR
authors.lastname: Wang
authors.forename: Chiu-Yin
authors.initials: CY
authors.lastname: Leung
authors.forename: Hing-Man
authors.initials: HM
authors.lastname: Ho
authors.forename: Stella
authors.initials: S
authors.lastname: Chai
authors.forename: Lee-Fong
authors.initials: LF
authors.lastname: Yau
authors.forename: Zhong-Zhen
authors.initials: ZZ
authors.lastname: Zhao
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Jiang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D036145:Ginsenosides / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D005894:Panax / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D053279:Polyynes / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D036145:Ginsenosides; D053279:Polyynes