title: Urgency is an independent factor for sleep disturbance in men with obstructive sleep apnea.
abstract: OBJECTIVE
  The relationship between overactive bladder (OAB) symptoms, other than nocturia, and sleep, has not been fully evaluated, although a close relationship between nocturia and sleep disturbance has been reported. In the present study, we evaluated the relationship between OAB symptoms and several polysomnography (PSG) parameters in middle-age men with sleep disturbance, especially to clarify whether urgency as the hallmark symptom of an OAB is independently associated with sleep quality.
  
  
  METHODS
  A total of 32 men >40 years of age (mean age 58.0 ± 12.6), who had been diagnosed with obstructive sleep apnea syndrome by PSG, were included in the present study. Their OAB symptoms were evaluated using the OAB symptom score (OABSS) before PSG. The relationship between the OABSS and several parameters, such as sleeping time, sleeping efficiency, sleep latency, percentage of rapid eye movement during sleeping time, and apnea/hypopnea index obtained from PSG, was evaluated.
  
  
  RESULTS
  Multivariate analysis showed that only sleeping efficiency was an influencing factor on the total OABSS. Of the 4 subscores of OABSS, including frequency, nocturia, urgency, and urgency incontinence, multivariate analysis showed that the subscores of nocturia and urgency were independent influencing factors on sleeping efficiency. Nocturia correlated negatively with sleeping efficiency (Pearson's correlation 0.533, P <.01), and urgency also correlated negatively with sleeping efficiency (Pearson's correlation 0.492, P <.01).
  
  
  CONCLUSIONS
  We found that urgency and nocturia were factors that independently affected sleep or were affected by sleep quality, although only the association of nocturia with sleep disturbance has been the focus of previous studies.
authors.affiliation: Department of Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. akitsuji@uro.med.osaka-u.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Tsujimura
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Takao
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Miyagawa
authors.forename: Keisuke
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Fukuhara
authors.forename: Jiro
authors.initials: J
authors.lastname: Nakayama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kiuchi
authors.forename: Nakamori
authors.initials: N
authors.lastname: Suganuma
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nakamura
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kumano-Go
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Sugita
authors.forename: Norio
authors.initials: N
authors.lastname: Nonomura
authors.forename: Akihiko
authors.initials: A
authors.lastname: Okuyama
mesh_terms: D000368:Aged; D015897:Comorbidity; D006801:Humans; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000150:complications / Q000453:epidemiology*; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000453:epidemiology*; D020919:Sleep Disorders, Intrinsic / Q000209:etiology*; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D053202:Urinary Incontinence, Urge / Q000150:complications / Q000453:epidemiology*