title: [Morphological characteristics of bone tissue regeneration process in young and old animals].
abstract: The paper describes the results of the morphological study of the bone tissue repair process in young and old animals on the model of bone skeleton damage. The defect of the cortical bone was reached by means of bringing in a teflon fistula to make a tunnel surrounded by bone tissue, providing condition for studying the character of bone marrow elements migration to the created hollow space. Repair processes in the bone tissue of old animals were found to elapse much slower than in young ones. However, administration of embryonic cartilaginous and bone tissue extracts into the area of bone defect in old animals facilitated the process of bone tissue repair. The obtained results may serve as a prerequisite for the development of methods for optimization of rehabilitation in old and senile patients with fractures of cortical bones.
authors.forename: I N
authors.initials: IN
authors.lastname: Kurilov
authors.forename: G A
authors.initials: GA
authors.lastname: Ryzhak
mesh_terms: D000375:Aging / Q000473:pathology* / Q000502:physiology; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D001861:Bone Regeneration; D001842:Bone and Bones / Q000737:chemistry / Q000196:embryology; D002356:Cartilage / Q000737:chemistry / Q000196:embryology; D002642:Chick Embryo; D005347:Fibroblasts / Q000473:pathology; D011817:Rabbits; D013977:Tibia / Q000187:drug effects / Q000293:injuries / Q000473:pathology*; D014020:Tissue Extracts / Q000302:isolation & purification / Q000627:therapeutic use; D014945:Wound Healing / Q000502:physiology
chemical_list: D014020:Tissue Extracts