title: A novel approach to indoloditerpenes by Nazarov photocyclization: synthesis and biological investigations of terpendole E analogues.
abstract: The application of the Nazarov photocyclization as a mild and efficient method for access to the basic core of novel indoloditerpenoid derivatives is reported. The detailed synthesis of these new analogues of terpendole E, as well as their evaluation as potential inhibitors of KSP, is described.
authors.affiliation: Department of Chemistry and Mineralogy, Institute of Organic Chemistry, University of Leipzig, Johannisallee 29, 04103 Leipzig, Germany.
authors.forename: Fátima
authors.initials: F
authors.lastname: Churruca
authors.forename: Manolis
authors.initials: M
authors.lastname: Fousteris
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Margarete von Wantoch
authors.initials: Mv
authors.lastname: Rekowski
authors.forename: Candide
authors.initials: C
authors.lastname: Hounsou
authors.forename: Thomas
authors.initials: T
authors.lastname: Surrey
authors.forename: Athanassios
authors.initials: A
authors.lastname: Giannis
mesh_terms: D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D010777:Photochemistry
chemical_list: D004224:Diterpenes; D007211:Indoles; C477863:terpendole E