title: POSVP(21), a major secretory androgen-dependent protein from sand rat seminal vesicles, identified as a transgelin.
abstract: The seminal vesicles of adult sand rat contain a major secretory protein band (MW 21 kDa) designated as Psammomys obesus seminal vesicles protein of 21 kDa (POSVP(21)). This protein is abundant in secretions, regulated by androgens and also present in the vaginal plug. POSVP(21) accounts for over 22.3% of soluble proteins from homogenate during the breeding season, 13.3% during the middle season and 5.3% during the hormonal regression season. It is absent during the non-breeding season. POSVP(21) is localized in the cytoplasm of epithelial cells and in secretory products in the lumen. It presents an immunological homology with two epididymal proteins with the same molecular weight and a high degree of homology with transgelin from rat (Rattus norvegicus).
authors.affiliation: Laboratory of Arid Areas, Biological Sciences Institute, USTHB, BP 132 El Alia, 16100 Algiers, Algeria. kacinaima@yahoo.fr
authors.forename: Naïma
authors.initials: N
authors.lastname: Kaci-Ouchfoun
authors.forename: Anne
authors.initials: A
authors.lastname: Incamps
authors.forename: Fatima
authors.initials: F
authors.lastname: Hadj-Bekkouche
authors.forename: Mohamed Cherif
authors.initials: MC
authors.lastname: Abbadi
authors.forename: Laurent
authors.initials: L
authors.lastname: Bellanger
authors.forename: Thérèse
authors.initials: T
authors.lastname: Gernigon-Spychalowicz
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000378:metabolism; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism; D005849:Gerbillinae / Q000502:physiology*; D008297:Male; D008840:Microfilament Proteins / Q000032:analysis / Q000378:metabolism*; D008970:Molecular Weight; D009124:Muscle Proteins / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D012621:Seasons; D029589:Seminal Plasma Proteins / Q000737:chemistry / Q000378:metabolism*; D012669:Seminal Vesicles / Q000378:metabolism*
chemical_list: D008840:Microfilament Proteins; D009124:Muscle Proteins; D029589:Seminal Plasma Proteins; C051615:transgelin
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