Dendritic cells: a question of upbringing.
Dendritic cells (DCs) arise from dedicated precursors and monocytes; however, the impact of these differential origins remain unclear. In this issue of Immunity, Siddiqui et al. (2010) describe a population of colitogenic monocyte-derived DCs that propagate intestinal inflammation.
Jung
Steffen
S
The Weizmann Institute of Science, Department of Immunology, Rehovot 76100, Israel. s.jung@weizmann.ac.il