title: Suppressing Aedes albopictus, an emerging vector of dengue and chikungunya viruses, by a novel combination of a monomolecular film and an insect-growth regulator.
abstract: The Asian tiger mosquito Aedes albopictus (Skuse) is rapidly increasing its global range and importance in transmission of chikungunya and dengue viruses. We tested pellet formulations of a monomolecular film (Agnique) and (S)-methoprene (Altosid) under laboratory and field conditions. In the laboratory, Agnique provided 80% control for 20 days, whereas Altosid, in combination with Agnique, provided 80% control for > 60 days. During field trials, the 1:1 pellet ratio of combined products provided > 95% control for at least 32 days and 50% control for at least 50 days. Altosid remained effective after a 107-day laboratory-induced drought, suggesting that the product serves as a means of control during drought conditions and against spring broods in temperate regions. Agnique and Altosid, when used in tandem for cryptic, difficult-to-treat locations, can provide long-term control of Ae. albopictus larvae and pupae. The possible additive or synergistic effects of the combined products deserve further investigation.
authors.affiliation: Center for Vector Biology, Department of Entomology, Rutgers University, New Brunswick, New Jersey, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Nelder
authors.forename: Banugopan
authors.initials: B
authors.lastname: Kesavaraju
authors.forename: Ary
authors.initials: A
authors.lastname: Farajollahi
authors.forename: Sean
authors.initials: S
authors.lastname: Healy
authors.forename: Isik
authors.initials: I
authors.lastname: Unlu
authors.forename: Taryn
authors.initials: T
authors.lastname: Crepeau
authors.forename: Ashok
authors.initials: A
authors.lastname: Ragavendran
authors.forename: Dina
authors.initials: D
authors.lastname: Fonseca
authors.forename: Randy
authors.initials: R
authors.lastname: Gaugler
mesh_terms: D000330:Aedes / Q000187:drug effects* / Q000502:physiology / Q000821:virology; D018354:Alphavirus Infections / Q000635:transmission* / Q000821:virology; D000818:Animals; D002646:Chikungunya virus; D021821:Communicable Diseases, Emerging / Q000517:prevention & control; D003715:Dengue / Q000635:transmission*; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D007306:Insecticides / Q000494:pharmacology; D007605:Juvenile Hormones / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D008567:Membranes, Artificial; D008726:Methoprene / Q000494:pharmacology; D009032:Mosquito Control / Q000379:methods*; D011679:Pupa / Q000187:drug effects
chemical_list: D007306:Insecticides; D007605:Juvenile Hormones; D008567:Membranes, Artificial; D008726:Methoprene