title: A rare cause of systolic murmur: unruptured right sinus of Valsalva aneurysm with right ventricular outflow tract obstruction and supracristal ventricular septal defect.
abstract: Dyspnea and heart murmur are common reasons for referrals in cardiology and both are associated with a broad differential diagnosis. Sinus of Valsalva aneurysms are rare abnormalities of the aortic root that should be considered in the differential diagnosis in young and middle aged patients. Sinus of Valsalva aneurysms are often associated with supracristal ventricular septal defects and can be identified on transthoracic echocardiography. Diagnosis of a SVA should trigger a careful search for ventricular septal defect, which may necessitate transesophageal echocardiography.
authors.affiliation: Department of Internal Medicine, Section of Cardiology, Hospital of Saint Raphael, New Haven, Connecticut 06511, USA. cionescu@srhs.org
authors.forename: Costin N
authors.initials: CN
authors.lastname: Ionescu
authors.forename: Vasant
authors.initials: V
authors.lastname: Khachane
authors.forename: Mark
authors.initials: M
authors.lastname: Earle
authors.forename: C Bogdan
authors.initials: CB
authors.lastname: Marcu
authors.forename: Andre
authors.initials: A
authors.lastname: Ghantous
authors.forename: Michael
authors.initials: M
authors.lastname: Chrissoheris
mesh_terms: D001014:Aortic Aneurysm / Q000150:complications / Q000000981:diagnostic imaging*; D004417:Dyspnea / Q000209:etiology; D017548:Echocardiography, Transesophageal; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012850:Sinus of Valsalva / Q000000981:diagnostic imaging*; D054160:Systolic Murmurs / Q000209:etiology*