title: Clinical effectiveness of transcervical polyp resection in women with endometrial polyps: randomized controlled trial.
abstract: OBJECTIVE
  To estimate the clinical effectiveness of transcervical resection of endometrial polyps.
  
  
  METHODS
  Randomized controlled trial (Canadian Task Force classification I).
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  One hundred fifty premenopausal women with endometrial polyps.
  
  
  METHODS
  Either transcervical resection of the polyp or observation for 6 months.
  
  
  RESULTS
  There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat.
  
  
  CONCLUSIONS
  Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.
authors.affiliation: Department of Gynecology and Obstetrics, Oslo University Hospital Ullevål, Oslo, Norway. m.lieng@online.no
authors.forename: Marit
authors.initials: M
authors.lastname: Lieng
authors.forename: Olav
authors.initials: O
authors.lastname: Istre
authors.forename: Leiv
authors.initials: L
authors.lastname: Sandvik
authors.forename: Vibeke
authors.initials: V
authors.lastname: Engh
authors.forename: Erik
authors.initials: E
authors.lastname: Qvigstad
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods*; D008875:Middle Aged; D017060:Patient Satisfaction; D018579:Patient Selection; D011127:Polyps / Q000601:surgery*; D016896:Treatment Outcome; D014591:Uterine Diseases / Q000601:surgery*