title: Distal cholangiocarcinoma with gastric metastasis mimicking early gastric cancer.
abstract: We report an unusual case of distal cholangiocarcinoma with gastric metastasis mimicking early gastric cancer. A 67-year-old woman presented with a 4-month history of abdominal pain after eating. Computed tomography showed a malignant tumor of the common bile duct located just above the intrapancreatic segment, and endoscopy revealed a 2-cm, flat, elevated lesion with convergence of the surrounding folds, situated at the gastric angle. Based on the endoscopic biopsy results, an adenocarcinoma, thought to be an early gastric cancer, was diagnosed. The patient underwent Whipples's operation. Histopathological findings showed that the adenocarcinomatous tissue was clearly demarcated and infiltrated the gastric mucosa and submucosa, leaving the gastric superficial mucosa intact. Both tumors showed similar pathological features and were positive for cytokeratin (CK)-19 and CK-7. These finding suggest distal cholangiocarcinoma with gastric metastasis.
authors.affiliation: Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.
authors.forename: Eun-Mi
authors.initials: EM
authors.lastname: Kim
authors.forename: Byung Seok
authors.initials: BS
authors.lastname: Lee
authors.forename: Hee Seok
authors.initials: HS
authors.lastname: Moon
authors.forename: Jae Kyu
authors.initials: JK
authors.lastname: Sung
authors.forename: Seok Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Heon Young
authors.initials: HY
authors.lastname: Lee
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Kang