title: Pulmonary metastasis with endobronchial spread from sinonasal melanoma during a 9-year follow-up.
abstract: A 60-year-old woman was diagnosed with pulmonary metastasis with endobronchial spread of sinonasal melanoma 9 years after the initial treatment. She had originally been diagnosed with sinonasal malignant melanoma and received chemotherapy combined with carbon ion radiotherapy. During routine follow-up, chest CT showed a nodular lesion on the left upper lung lobe. Bronchoscopic examination showed diffuse melanosis without intrinsic masses from the left main bronchus to the peripheral bronchial mucosa. Transbronchial biopsy was performed for both the pulmonary lesion and endobronchial melanosis lesions. Melanoma cells were histologically detected in both the mucosal and submucosal layers.
authors.affiliation: Division of Thoracic Diseases, Chiba Cancer Center.
authors.forename: Saori
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakajima
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Iizasa
authors.forename: Hideki
authors.initials: H
authors.lastname: Tsujimura
authors.forename: Makiko
authors.initials: M
authors.lastname: Itami
authors.forename: Hideki
authors.initials: H
authors.lastname: Kimura
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D008545:Melanoma / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary*; D008875:Middle Aged; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents