title: Fabry-Pérot cavity sensors for multipoint on-column micro gas chromatography detection.
abstract: We developed and characterized a Fabry-Pérot (FP) sensor module based micro gas chromatography (microGC) detector for multipoint on-column detection. The FP sensor was fabricated by depositing a thin layer of metal and a layer of gas-sensitive polymer consecutively on the endface of an optical fiber, which formed the FP cavity. Light partially reflected from the metal layer and the polymer-air interface generated an interference spectrum, which shifted as the polymer layer absorbed the gas analyte. The FP sensor module was then assembled by inserting the FP sensor into a hole drilled in the wall of a fused-silica capillary, which can be easily connected to the conventional gas chromatography (GC) column through a universal quick seal column connector, thus enabling on-column real-time detection. We characterized the FP sensor module based microGC detector. Sensitive detection of various gas analytes was achieved with subnanogram detection limits. The rapid separation capability of the FP sensor module assembled with both single- and tandem-column systems was demonstrated, in which gas analytes having a wide range of polarities and volatilities were well-resolved. The tandem-column system obtained increased sensitivity and selectivity by employing two FP sensor modules coated with different polymers, showing great system versatility.
authors.affiliation: Department of Biomedical Engineering, University of Michigan, 1101 Beal Avenue, Ann Arbor, Michigan 48109, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Yuze
authors.initials: Y
authors.lastname: Sun
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Howard
authors.forename: Greg
authors.initials: G
authors.lastname: Frye-Mason
authors.forename: Aaron K
authors.initials: AK
authors.lastname: Thompson
authors.forename: Shiou-Jyh
authors.initials: SJ
authors.lastname: Ja
authors.forename: Siao-Kwan
authors.initials: SK
authors.lastname: Wang
authors.forename: Mengjun
authors.initials: M
authors.lastname: Bai
authors.forename: Haskell
authors.initials: H
authors.lastname: Taub
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Almasri
authors.forename: Xudong
authors.initials: X
authors.lastname: Fan
mesh_terms: D000388:Air; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D002849:Chromatography, Gas / Q000379:methods*; D008670:Metals / Q000737:chemistry; D055100:Optical Fibers; D011092:Polyethylene Glycols / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry; D013696:Temperature
chemical_list: D008670:Metals; D011092:Polyethylene Glycols; D012822:Silicon Dioxide