Complexity in common diseases: big biology for all.
The Commentary of Mills and Sykes in Science Translational Medicine presented their thesis on the advent of high-throughput technologies and the dangers they may represent for the future of biomedical research. In response, we argue that true progress on the diagnosis and treatment of common human diseases will require the advent of big biology and its deep integration with focused research as practiced in both academic and industrial institutions.
Lamb
John R
JR
Oncology Research Unit, Pfizer, San Diego, CA 92121, USA. John.Lamb@pfi zer.com
Gibson
Neil W
NW
D001695:Biology; D035843:Biomedical Research / Q000379:methods*; D001709:Biotechnology / Q000379:methods*; D004194:Disease; D006801:Humans; D008511:Medicine / Q000379:methods*