Optofluidic platforms based on surface-enhanced Raman scattering.
We report recent progress in the development of surface-enhanced Raman scattering (SERS)-based optofluidic platforms for the fast and sensitive detection of chemical and biological analytes. In the current context, a SERS-based optofluidic platform is defined as an integrated analytical device composed of a microfluidic element and a sensitive Raman spectrometer. Optofluidic devices for SERS detection normally involve nanocolloid-based microfluidic systems or metal nanostructure-embedded microfluidic systems. In the current review, recent advances in both approaches are surveyed and assessed. Additionally, integrated real-time sensing systems that combine portable Raman spectrometers with microfluidic devices are also reviewed. Such real-time sensing systems have significant utility in environmental monitoring, forensic science and homeland defense applications.
Lim
Chaesung
C
Department of Bionano Engineering, Hanyang University, Ansan 426-791, South Korea.
Hong
Jongin
J
Chung
Bong Geun
BG
deMello
Andrew J
AJ
Choo
Jaebum
J
D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D008904:Miniaturization; D049329:Nanostructures / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods