title: The highly enantioselective Michael addition of ketones to nitrodienes catalyzed by the efficient organocatalyst system of pyrrolidinyl-thioimidazole and chiral thioureido acid.
abstract: The highly enantioselective Michael addition reaction of ketones to nitrodienes was promoted efficiently by the accessible and fine-tunable organocatalytic system of pyrrolidinyl-thioimidazole and chiral thioureido acid. The corresponding adducts were afforded in good yields with high diastereoselectivities (up to 99 : 1) and excellent enantioselectivities (up to 99% ee).
authors.affiliation: State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou, China.
authors.forename: Zhao-Bo
authors.initials: ZB
authors.lastname: Li
authors.forename: Shu-Ping
authors.initials: SP
authors.lastname: Luo
authors.forename: Yi
authors.initials: Y
authors.lastname: Guo
authors.forename: Ai-Bao
authors.initials: AB
authors.lastname: Xia
authors.forename: Dan-Qian
authors.initials: DQ
authors.lastname: Xu