title: Palliative radiotherapy with 1 x 8 Gy using conformal radiotherapy for chemotherapy-refractory, recurrent, aggressive lymphomas.
abstract: We performed palliative radiotherapy with a single-fraction of 8 Gy using a three-dimensional conformal radiotherapy (3D-CRT) technique for patients with dyspnea due to a bulky nasooropharyngeal lesion who had chemotherapy-refractory, recurrent, aggressive lymphoma. After palliative radiotherapy, a complete response with acceptable toxicity was achieved at the irradiated sites of two patients, and the symptoms resolved completely. These results indicated that a single fraction of 8 Gy using 3D-CRT is an effective palliative treatment for chemotherapy-refractory, recurrent, aggressive lymphoma.
authors.affiliation: Department of Radiology, Kanazawa Medical University, Kahoku, Ishikawa, Japan. m-matoba@kanazawa-med.ac.jp
authors.forename: Munetaka
authors.initials: M
authors.lastname: Matoba
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Oota
authors.forename: Hisao
authors.initials: H
authors.lastname: Tonami
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Masaki
authors.forename: Tomouki
authors.initials: T
authors.lastname: Sakai
authors.forename: Hisanori
authors.initials: H
authors.lastname: Umehara
mesh_terms: D000368:Aged; D019583:Dose Fractionation, Radiation; D019008:Drug Resistance, Neoplasm; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000532:radiotherapy*; D020522:Lymphoma, Mantle-Cell / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D010166:Palliative Care; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal