[Mortality characteristics in people with systemic lupus erythematosus].
The paper gives a brief overview of trends in mortality from lupus, risk factors and causes of death. At the end of the compressed mortalitetnim modest knowledge about the characteristics of SLE in Croatia and proposed measures for its reduction. Despite the significant decline of specific mortality rates, which captures the 50th year to date, long-term survival of patients is not satisfactory. Accelerated atherosclerosis with cerebrovascular and cardiovascular complications, infections and diseases zlocudne the most important causes of death in SLE. Race, age, gender, ethnicity, social and economic status of patients and the characteristics of the disease, primarily lupus nephritis, treatment and environmental influences, the factors affecting the mortality. In Croatia, the overall mortality rate of a specific axis of SLE is low, but there is a clear excess preuranjenih death and excess mortality in comparison with neighboring Slovenia. Therefore, in conclusion, the proposals amount to measures to reduce mortality: recognition and aggressive treatment of traditional and non-classical risk factors of atherosclerosis, reduction of disease activity with the least possible use of non-steroidal glucocorticoids ii antireumatika, adequate treatment of lupus nephritis, timely antiagregacijska and antikoagulacijska therapy in patients with increased risk thromboembolic incidents and patients with antiphospholipid syndrome. Educational and organizational measures to improve the availability and quality of health care affected by the centralization of the most difficult patients.
Mayer
Miroslav
M
Zavod za klinicku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb. mmayer@kbc-zagreb.hr
D002423:Cause of Death; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000401:mortality*; D012307:Risk Factors