Osteoinduction: translating preclinical promise into clinical reality.
This review, the second in a series of three editorials, focuses on the problems of translating basic scientific research on induction of bone into reliable clinical applications.
Ferretti
Carlo
C
Division of Maxillofacial and Oral Surgery, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa. ferretti@mweb.co.za
Ripamonti
Ugo
U
Tsiridis
Eleftherios
E
Kerawala
Cyrus J
CJ
Mantalaris
Athanasios
A
Heliotis
Manolis
M
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000494:pharmacology; D001861:Bone Regeneration / Q000187:drug effects / Q000235:genetics; D003094:Collagen; D006801:Humans; D018482:Muscle, Skeletal; D011994:Recombinant Proteins / Q000494:pharmacology; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D016212:Transforming Growth Factor beta / Q000494:pharmacology
D019485:Bone Morphogenetic Proteins; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; D003094:Collagen