title: Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system.
abstract: A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.
authors.affiliation: Department and Graduate Institute of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Hsiao-Lin
authors.initials: HL
authors.lastname: Hwa
authors.forename: James Chun-I
authors.initials: JC
authors.lastname: Lee
authors.forename: Yih-Yuan
authors.initials: YY
authors.lastname: Chang
authors.forename: Hsiang-Yi
authors.initials: HY
authors.lastname: Yin
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Chen
authors.forename: Li-Hui
authors.initials: LH
authors.lastname: Tseng
authors.forename: Yi-Ning
authors.initials: YN
authors.lastname: Su
authors.forename: Tsang-Ming
authors.initials: TM
authors.lastname: Ko
mesh_terms: D041321:Chromosomes, Human, X; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D008297:Male; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D013624:Taiwan; D020080:Tandem Repeat Sequences
chemical_list: D005819:Genetic Markers