title: Acute heart failure due to transient left ventricular dyssynchrony: case study.
abstract: This case study describes an unusual cause of acute heart failure that resolved with early beta-blockade therapy. A 52-year-old woman who had acute heart failure with severe left ventricular systolic dysfunction and left bundle branch block was admitted to a university medical center. Contrast-enhanced magnetic resonance images of the heart did not show any evidence of myocardial infarction or myocarditis. Rate-related left bundle branch block and subsequent left ventricular dyssynchrony resulted in acute systolic dysfunction that resolved with beta-blockade therapy that allowed heart rate control and narrowing of the QRS complex. Of note, the use of inotropic agents would have dramatically worsened the cardiac condition.
authors.affiliation: Intensive Care Unit, Cardiology Hospital, Centre Hospitalier Régional et Universitaire, Lille, France.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Jourdain
authors.forename: Jean Jacques
authors.initials: JJ
authors.lastname: Bauchart
authors.forename: Jean Luc
authors.initials: JL
authors.lastname: Auffray
authors.forename: Thierry H
authors.initials: TH
authors.lastname: LeJemtel
authors.forename: Philippe
authors.initials: P
authors.lastname: Asseman
authors.forename: Pierre Vladimir
authors.initials: PV
authors.lastname: Ennezat
mesh_terms: D000208:Acute Disease; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D002037:Bundle-Branch Block / Q000150:complications / Q000000981:diagnostic imaging; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D016896:Treatment Outcome; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000150:complications* / Q000000981:diagnostic imaging
chemical_list: D000319:Adrenergic beta-Antagonists