title: Bilateral acute angle-closure associated with systemic lymphoma: a report of 2 cases.
abstract: Bilateral acute angle-closure is a rare occurrence. When the central anterior chambers are shallow, it is often associated with systemic disease. We present 2 patients with atypical bilateral acute angle-closure as the presentation of systemic lymphoma. In these patients, angle closure may be caused by a uveal effusion or swelling of the ciliary body. If an atypical bilateral acute angle-closure attack cannot be attributed to a drug reaction or a bilateral iatrogenic cause, the patient should be evaluated for an associated systemic disease. In some patients, the acute angle-closure cannot be fully resolved until the underlying disease is treated. This report discusses the spectrum of presentations and the various diseases that have been associated with bilateral acute angle-closure.
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Cristol
authors.forename: Jane Gwira
authors.initials: JG
authors.lastname: Baumblatt
authors.forename: Evelyn
authors.initials: E
authors.lastname: Icasiano
authors.forename: Alana L
authors.initials: AL
authors.lastname: Grajewski
authors.forename: Mildred M G
authors.initials: MM
authors.lastname: Olivier
authors.forename: Richard K
authors.initials: RK
authors.lastname: Parrish
mesh_terms: D000208:Acute Disease; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D001761:Bleomycin / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D007839:Functional Laterality; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis* / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D002955:Leucovorin / Q000627:therapeutic use; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D000959:Antihypertensive Agents; D005938:Glucocorticoids; D001761:Bleomycin; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D002955:Leucovorin; D011241:Prednisone; D008727:Methotrexate