title: The secreted proteome profile of developing Dictyostelium discoideum cells.
abstract: Dictyostelium discoideum is a unicellular eukaryote that, when starved, aggregates to form multicellular structures. In this report, we identified the proteins secreted by developing Dictyostelium cells using MS-based proteomics. A total of 349 different secreted proteins were identified, indicating that at least 2.6% of the 13 600 predicted proteins in the Dictyostelium genome are secreted. Gene ontology analysis suggests that many of the secreted proteins are involved in protein and carbohydrate metabolism, and proteolysis.
authors.affiliation: Department of Biochemistry and Cell Biology, Rice University, Houston, TX, USA.
authors.forename: Deenadayalan
authors.initials: D
authors.lastname: Bakthavatsalam
authors.forename: Richard H
authors.initials: RH
authors.lastname: Gomer
mesh_terms: D004023:Dictyostelium / Q000737:chemistry* / Q000378:metabolism; D020543:Proteome / Q000032:analysis* / Q000378:metabolism; D040901:Proteomics; D015800:Protozoan Proteins / Q000032:analysis* / Q000378:metabolism
chemical_list: D020543:Proteome; D015800:Protozoan Proteins