Copper-catalyzed remote sp3 C-H chlorination of alkyl hydroperoxides.
A copper-catalyzed methodology to functionalize remote sp(3) C-H bonds in alkyl hydroperoxides is presented. The atom-transfer chlorination utilizes simple ammonium chloride salts as the chlorine source, and the internal redox process requires no external redox reagents.
Kundu
Rituparna
R
Department of Chemistry, Rice University, Houston, Texas 77005, USA.
Ball
Zachary T
ZT