title: gammadelta T-cells: basic features and potential role in vasculitis.
abstract: gammadelta T-cells are a numerically small subset of T-cells with distinct features. They recognise antigens that are not seen by other immune cells. At the functional level, gammadelta T-cells share some features with alphabeta T-cells but also exert functions that are otherwise performed by specialised subsets of alphabeta T-cells (e.g. IL-17 production, regulatory activity). We discuss the potential role of gammadelta T-cells in various clinical forms of vasculitis.
authors.affiliation: Institute of Immunology, University of Kiel, Kiel, Germany. kabelitz@immunologie.uni-kiel.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Kabelitz
authors.forename: Juliane
authors.initials: J
authors.lastname: Fazio
authors.forename: Sabine
authors.initials: S
authors.lastname: Adam-Klages
authors.forename: Matthias
authors.initials: M
authors.lastname: Marget
authors.forename: Hans Heinrich
authors.initials: HH
authors.lastname: Oberg
authors.forename: Daniela
authors.initials: D
authors.lastname: Wesch
authors.forename: Peter
authors.initials: P
authors.lastname: Lamprecht
mesh_terms: D000818:Animals; D006801:Humans; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014657:Vasculitis / Q000276:immunology*
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta