title: Unilateral blindness with third cranial nerve palsy and abnormal enhancement of extraocular muscles on magnetic resonance imaging of orbit after the ingestion of methanol.
abstract: Methanol is generally known to cause visual impairment and various systemic manifestations. There are a few reported specific findings for methanol intoxication on magnetic resonance imaging (MRI) of the brain. A case is reported of unilateral blindness with third cranial nerve palsy oculus sinister (OS) after the ingestion of methanol. Unilateral damage of the retina and optic nerve were confirmed by fundoscopy, flourescein angiography, visual evoked potential and electroretinogram. The optic nerve and extraocular muscles (superior rectus, medial rectus, inferior rectus and inferior oblique muscle) were enhanced by gadolinium-DTPA on MRI of the orbit. This is the first case report of permanent monocular blindness with confirmed unilateral damage of the retina and optic nerve, combined with third cranial nerve palsy after methanol ingestion.
authors.affiliation: Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Tae Nyoung
authors.initials: TN
authors.lastname: Chung
authors.forename: Sun Wook
authors.initials: SW
authors.lastname: Kim
authors.forename: Yoo Seok
authors.initials: YS
authors.lastname: Park
authors.forename: Incheol
authors.initials: I
authors.lastname: Park
mesh_terms: D000328:Adult; D001766:Blindness / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D000432:Methanol / Q000506:poisoning*; D009801:Oculomotor Muscles / Q000473:pathology; D015840:Oculomotor Nerve Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012997:Solvents / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D012997:Solvents; D000432:Methanol