[Influence of allogenic and autologic multipotent stromal cells of adipose tissue upon bone tissue regeneration in the rabbit mandible angle defect].
Reconstructive surgery often collides with complicated task of defect recovery in the situation of deficit of maxillofacial skeleton tissues, that leads to necessary search of accessible cells source with osteogenic potentials and proper substrate for cell transplantation. In the study the regeneratory potential of stromal cells of adipose tissue was tested in the rabbit model of mandible through angle defect. Cells of allogenic and autologic nature stimulated reparative osteogenesis but their influence upon bone matrix maturation was different. When the construction with allogenic cells was transplanted reaction of its rejection was not detected on histological level.
Cherniaev
S E
SE
Kiseleva
E V
EV
Grigor'ian
A S
AS
Volozhin
A I
AI
D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D001857:Bone Matrix / Q000502:physiology; D001861:Bone Regeneration; D002454:Cell Differentiation; D005500:Follow-Up Studies; D008334:Mandible / Q000502:physiology / Q000601:surgery*; D039902:Multipotent Stem Cells / Q000502:physiology / Q000637:transplantation; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits; D033581:Stem Cell Transplantation; D017154:Stromal Cells / Q000502:physiology / Q000637:transplantation; D013997:Time Factors; D023822:Tissue Engineering; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous