[Alimentary factors predisposing to colorectal cancer risk: a prospective epidemiologic study].
BACKGROUND
Some foods are incriminated in the genesis of colorectal cancers (CRC), on the other hand, other foods are considered as protectors.


OBJECTIVE
This study aimed to determine the alimentary factors influencing the risk of CRC.


METHODS
We conducted an epidemiologic prospective study. We performed firstly a descriptive analysis of the CRC group (32 patients) and we compared this group to a control group of 61 patients subdivided into two subgroups [Non tumoral digestive disease (31 patients) and a subgroup of trauma patients (30 patients)]. Factors, retained by the univariate analysis were introduced into a logistic regression model which identified the independent factors influencing the risk of CRC.


RESULTS
Univariate analysis identified 12 factors influencing the risk of CRC with p < or = 0.05: age, sex, geographical origin, anemia, addiction to smoking, sport activity, walk, processed meat, milk, fruits, oil and frying. The multivariate analysis identified three factors: age 40/60 years (OR: 5.15), processed meat consumption; frequent/rare (OR: 5.1), milk consumption rare/frequent (OR: 7.07).


CONCLUSIONS
For young people, a frequent consumption of processed meat increases the risk of CRC. However the frequent consumption of milk protects against CRC. We recommend to young people consumption of milk and avoiding frequent consumption of processed meat.
Guesmi
Fethi
F
Service de Chirurgie Générale, Centre de Traumatologie et des Grands Brûlés, Ben Arous.
Zoghlami
Ayoub
A
Sghaiier
Dorra
D
Nouira
Ramzi
R
Dziri
Chadli
C
D000328:Adult; D000367:Age Factors; D000818:Animals; D016022:Case-Control Studies; D015179:Colorectal Neoplasms / Q000453:epidemiology*; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D008461:Meat Products / Q000009:adverse effects; D008875:Middle Aged; D008892:Milk; D015999:Multivariate Analysis; D011446:Prospective Studies; D018570:Risk Assessment; D014416:Tunisia / Q000453:epidemiology