Caenorhabditis elegans as an alternative model host for legionella pneumophila, and protective effects of Bifidobacterium infantis.
The survival times of Caenorhabditis elegans worms infected with Legionella pneumophila from day 7.5 or later after hatching were shorter than those of uninfected worms. However, nematodes fed bifidobacteria prior to Legionella infection were resistant to Legionella. These nematodes may act as a unique alternative host for Legionella research.
Komura
Tomomi
T
Department of Interdisciplinary Studies for Advanced Aged Society, Osaka City University Graduate School of Human Life Science, Osaka 558-8585, Japan.
Yasui
Chikako
C
Miyamoto
Hiroshi
H
Nishikawa
Yoshikazu
Y
D000818:Animals; D000898:Antibiosis; D001644:Bifidobacterium / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D017173:Caenorhabditis elegans / Q000382:microbiology*; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D016952:Legionella pneumophila / Q000254:growth & development* / Q000472:pathogenicity*; D016019:Survival Analysis; D013997:Time Factors