Organocatalytic Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes.
To map out the efficient organocatalyst requirements in the Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes, a dozen different amino organocatalysts containing a p-toluenesulfonyl group (Ts) have been evaluated; excellent enantio-selectivities (up to er 92:8) were obtained with a primary amine-based Ts-DPEN catalyst and a plausible catalytic reaction mechanism was proposed on the basis of the experimental results.
Jiang
Zhen-Yu
ZY
Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, China.
Yang
Hua-Meng
HM
Ju
Ya-Dong
YD
Li
Li
L
Luo
Meng-Xian
MX
Lai
Guo-Qiao
GQ
Jiang
Jian-Xiong
JX
Xu
Li-Wen
LW
D002384:Catalysis; D007189:Indans / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry*; D014105:Tosyl Compounds / Q000737:chemistry*
D007189:Indans; D013343:Styrenes; D014105:Tosyl Compounds