title: Features of polycythemia vera in the 8p12 myeloproliferative syndrome.
abstract: The 8p12 myeloproliferative syndrome is a distinct myeloid disorder associated with a translocation involving chromosome region 8p12 (HUGO nomenclature). It is characterized by leukocytosis, eosinophilia, and a concurrent or rapid transformation to a T-cell lymphoblastic lymphoma. We report a case of polycythemia vera as a clinical presentation of the 8p12 myeloproliferative syndrome and review the literature. Atypical features in patients with polycythemia vera should be investigated with cytogenetic evaluation.
authors.affiliation: Department of Internal Medicine and Pathology and Laboratory Medicine, University of California at Davis, Sacramento, CA 95817, USA. jeanna.welborn@ucdmc.ucdavis.edu
authors.forename: Jeanna
authors.initials: J
authors.lastname: Welborn
authors.forename: Shelly
authors.initials: S
authors.lastname: Fenner
authors.forename: Robert
authors.initials: R
authors.lastname: Parks
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000235:genetics*; D013577:Syndrome; D055815:Young Adult