The effect of smoking on gingival crevicular fluid levels of myeloperoxidase.
OBJECTIVE
To compare the gingival crevicular fluid (GCF) myeloperoxidase (GM) levels in smokers and non-smokers.


METHODS
This study comprised 45 subjects: (a) 12 smokers with periodontitis, (b) 10 non-smokers with periodontitis, (c) 11 smokers with healthy periodontium, and (d) 12 non-smokers with healthy periodontium were recruited for the study and their GM levels were analyzed.


CONCLUSIONS
GM levels were significantly higher in smokers with periodontitis compared with others. Hence, more incidence of mutagenesis and cytotoxicity were noted at sites of inflammation mediated by GM in smokers compared with non-smokers.
Rai
Balwant
B
Medical Imaging and Forensic Odontology Section, School of Dentistry, Rohtak, Haryana, India.
Kaur
Jasdeep
J
Anand
S C
SC
Laller
Kuldeep
K
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D016022:Case-Control Studies; D055113:Chronic Periodontitis / Q000201:enzymology*; D005883:Gingival Crevicular Fluid / Q000201:enzymology*; D006801:Humans; D016296:Mutagenesis; D009195:Peroxidase / Q000032:analysis*; D012907:Smoking / Q000378:metabolism*; D055815:Young Adult
D015415:Biomarkers; D009195:Peroxidase