Proposing a relationship between Mycobacterium avium subspecies paratuberculosis infection and Hashimoto's thyroiditis.
Humans are widely exposed to Mycobacterium avium subspecies paratuberculosis (MAP), a proven multi-host chronic enteric pathogen that has recently been linked to autoimmune diabetes. In the present study we used a MAP species-specific polymerase chain reaction with the insertion element IS900-specific probe to detect MAP infection in members of the same family suffering from Hashimoto's thyroiditis.
Sisto
Margherita
M
Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy. m.sisto@anatomia.uniba.it
Cucci
Liana
L
D'Amore
Massimo
M
Dow
Thomas C
TC
Mitolo
Vincenzo
V
Lisi
Sabrina
S
D015342:DNA Probes; D004251:DNA Transposable Elements / Q000235:genetics*; D050031:Hashimoto Disease / Q000382:microbiology*; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D016927:Mycobacterium avium subsp. paratuberculosis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010283:Paratuberculosis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D016133:Polymerase Chain Reaction / Q000379:methods; D013045:Species Specificity
D015342:DNA Probes; D004251:DNA Transposable Elements