title: Oral manifestations leading to the diagnosis of familial tuberous sclerosis.
abstract: Clinical manifestations of tuberous sclerosis (TS) are variable, and oral involvement occurs in less than 10% of the affected patients. We reported herein a nine-year-old boy with dental enamel pits and gingival nodular lesions, histologically diagnosed as angiofibromas that leaded to the diagnosis of a family with TS. In this report, we demonstrated the multiprofessional importance in the diagnosis of TS. Early diagnosis of TS is essential for an appropriate treatment of the affected patients and genetic counseling.
authors.affiliation: Department of Oral Diagnosis, Dental School, Montes Claros, Minas Gerais, Brazil.
authors.forename: Hercilio
authors.initials: H
authors.lastname: Martelli
authors.forename: Leonardo Santos
authors.initials: LS
authors.lastname: Lima
authors.forename: Paulo Rogerio Ferreti
authors.initials: PR
authors.lastname: Bonan
authors.forename: Ricardo D
authors.initials: RD
authors.lastname: Coletta
mesh_terms: D018322:Angiofibroma / Q000209:etiology*; D002648:Child; D003744:Dental Enamel Hypoplasia / Q000209:etiology*; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000209:etiology*; D005887:Gingival Neoplasms / Q000209:etiology*; D006801:Humans; D008297:Male; D010348:Patient Care Team; D014402:Tuberous Sclerosis / Q000150:complications / Q000175:diagnosis*