title: Effectiveness of a mindfulness-based cognitive therapy program as an adjunct to pharmacotherapy in patients with panic disorder.
abstract: Mindfulness-based cognitive therapy (MBCT) has been studied to treat patients with depressive or anxiety disorders. The aim of this study was to examine whether MBCT is effective as an adjunct to pharmacotherapy in the treatment of patients with panic disorder. Twenty-three patients with panic disorder were included in a MBCT program for a period of 8 weeks. The Hamilton Anxiety Rating Scale (HAM-A), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Anxiety Sensitivity Index-Revised (ASI-R), Albany Panic and Phobia Questionnaire (APPQ), and Panic Disorder Severity Scale (PDSS) were used to assess the patients during the MBCT program. Both HAM-A and PDSS scores were significantly decreased at the 2nd, 4th and 8th weeks compared to baseline in the patients with panic disorder (HAM-A, p<0.01; PDSS, p<0.01). Also, BAI, APPQ and ASI-R were improved significantly after MBCT program (BAI, p<0.01; APPQ, p<0.01; ASI-R, p<0.01). In addition, all subscale scores of ASI-R decreased significantly. MBCT could be effective as an adjunct to pharmacotherapy in patients with panic disorder. However, randomized controlled trials are needed.
authors.affiliation: Department of Psychiatry, CHA Bundang Medical Center, CHA University, 351 Yatap, Bundang, Seongnam-si, Republic of Korea.
authors.forename: Borah
authors.initials: B
authors.lastname: Kim
authors.forename: Sang-Hyuk
authors.initials: SH
authors.lastname: Lee
authors.forename: Yong Woo
authors.initials: YW
authors.lastname: Kim
authors.forename: Tai Kiu
authors.initials: TK
authors.lastname: Choi
authors.forename: Keunyoung
authors.initials: K
authors.lastname: Yook
authors.forename: Shin Young
authors.initials: SY
authors.lastname: Suh
authors.forename: Sung Joon
authors.initials: SJ
authors.lastname: Cho
authors.forename: Ki-Hwan
authors.initials: KH
authors.lastname: Yook
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D019122:Meditation; D008875:Middle Aged; D016584:Panic Disorder / Q000523:psychology / Q000628:therapy*; D018579:Patient Selection; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents