Real-time contrast-enhanced ultrasound imaging of focal liver lesions in fatty liver.
OBJECTIVE
The objective of this study was to investigate the contrast-enhanced ultrasound (CEUS) imaging features of focal liver lesions (FLLs) in fatty liver.


METHODS
One hundred FLLs in 98 patients with fatty liver were evaluated with real-time CEUS.


RESULTS
All malignant FLLs showed hyperenhancement in arterial phase and contrast washout in portal and late phases. Among the FLLs, 3.3% of hemangiomas, 12.5% of focal nodular hyperplasias (FNHs), and 2.5% of focal fatty sparing lesions showed contrast washout in the late phase. The sensitivity and specificity for the characterization of hepatocellular carcinoma, metastasis, hemangioma, FNH, and focal fatty sparing lesions were 100% and 95.6%, 60% and 100%, 93.3% and 98.6%, 87.5% and 97.8%, and 92.6% and 100%, respectively.


CONCLUSIONS
Correct characterization of FLLs in fatty liver by CEUS is possible based on their typical enhancement patterns.
Liu
Guang-Jian
GJ
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Wang
Wei
W
Xie
Xiao-Yan
XY
Xu
Hui-Xiong
HX
Xu
Zuo-Feng
ZF
Zheng
Yan-Ling
YL
Liang
Jin-Yu
JY
Moriyasu
Fuminori
F
Lu
Ming-De
MD
D000328:Adult; D000368:Aged; D003199:Computer Systems; D003287:Contrast Media; D005234:Fatty Liver / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D045423:Microbubbles; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013459:Sulfur Hexafluoride; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult
D003287:Contrast Media; D013459:Sulfur Hexafluoride