Combined vasomodulatory therapy for severe pulmonary hypertension in chronic hypersensitivity pneumonitis.
BACKGROUND
There are only a few reports of pulmonary hypertension (PH) in hypersensitivity pneumonitis (HP) and an approved vasomodulatory therapy for PH does not exist at all for interstitial lung disease (ILD), particularly for HP.


METHODS
The case of a 53-year-old woman with chronic HP and severe life-threatening PH treated with a combined specific vasomodulatory therapy is reported. Sustained clinical and hemodynamic improvement was achieved.


CONCLUSIONS
Further investigation of PH in HP and specific vasomodulatory therapy is necessary.
Koschel
Dirk Steffen
DS
Department of Pulmonary Diseases, Fachkrankenhaus Coswig, Centre for Pulmonary Diseases and Thoracic Surgery, Coswig, Germany. dr.koschel@fachkrankenhaus-coswig.de
Kolditz
Martin
M
Höeffken
Gert
G
Halank
Michael
M
D000542:Alveolitis, Extrinsic Allergic / Q000150:complications*; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000188:drug therapy*; D016285:Iloprost / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D010666:Phenylpropionates / Q000627:therapeutic use*; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use*; D011687:Purines / Q000008:administration & dosage / Q000627:therapeutic use; D011724:Pyridazines / Q000627:therapeutic use*; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000008:administration & dosage / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D010666:Phenylpropionates; D010879:Piperazines; D011687:Purines; D011724:Pyridazines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; C467894:ambrisentan; D016285:Iloprost