title: Colorectal cancer distribution in 220 Indian patients undergoing colonoscopy.
abstract: OBJECTIVE
  Colorectal cancer is one of the major cancers in the developed world. The incidence of colorectal cancer is low in India. The aim of the present study was to describe the anatomical distribution and age at diagnosis of colorectal cancer in India.
  
  
  METHODS
  Retrospective descriptive analysis of anatomical distribution, age at diagnosis and demography of 220 cases (149 [67.7%] men) of adenocarcinoma of the colon or rectum diagnosed at colonoscopy over a period of five years.
  
  
  RESULTS
  The mean age at diagnosis was 58.4 years (SD 13.3; range 23-85 years). Twenty-eight (12.7%) cases were below the age of 40 years. The majority (31.8%) cases were aged between 61-70 years. Most of the tumors (n=163, 74%) were located distal to the splenic flexure. Multivariate logistic regression analysis showed that bleeding per rectum (OR 2.8; 95% CI 1.2-6.2) was associated with distal cancer, and palpable mass (OR 3.9; 95% CI 1.7-8.6) was associated with proximal cancer.
  
  
  CONCLUSIONS
  Almost one-third of the colorectal cancers in this series occurred in the seventh decade and were located distal to the splenic flexure.
authors.affiliation: Department of Gastroenterology, Amritha Institute of Medical Sciences And Research Center, Kochi, Kerala, 682 041, India. musthafacpdr@gmail.com
authors.forename: Musthafa Chalikandy
authors.initials: MC
authors.lastname: Peedikayil
authors.forename: Prem
authors.initials: P
authors.lastname: Nair
authors.forename: S M
authors.initials: SM
authors.lastname: Seena
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Radhakrishnan
authors.forename: Shine
authors.initials: S
authors.lastname: Sadasivan
authors.forename: V A
authors.initials: VA
authors.lastname: Naryanan
authors.forename: V
authors.initials: V
authors.lastname: Balakrishnan
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D055815:Young Adult