title: Clinical characteristics of delayed endolymphatic hydrops in Japan: A nationwide survey by the Peripheral Vestibular Disorder Research Committee of Japan.
abstract: CONCLUSIONS
  Similarly to almost all delayed endolymphatic hydrops (DEH) cases with both precedent sudden deafness and mumps deafness, two-thirds of DEH cases with precedent deafness of unknown cause with onset in early childhood developed DEH symptoms within 40 years after the precedent deafness. In spite of the diagnosis of precedent deafness, viral labyrinthitis may build up the late endolymphatic hydrops in most DEH cases up to four decades.
  
  
  OBJECTIVE
  To clarify the characteristics of DEH in Japan.
  
  
  METHODS
  Clinical information on 198 DEH cases was collected by nationwide, multicenter surveys conducted by the Peripheral Vestibular Disorders Research Committee of Japan.
  
  
  RESULTS
  The incidence of the ipsilateral type of DEH was 47.5%, which was almost equal to that of the contralateral type. In both types of DEH, the most common diagnosis of precedent deafness was deafness of unknown cause with onset in early childhood: 43.9% in both types of DEH. Sudden deafness and mumps deafness were the subsequent diagnoses of precedent deafness. The distribution of time delay of the onset between precedent deafness of unknown cause with onset in early childhood and DEH was different from that between precedent sudden and mumps deafness and DEH.
authors.affiliation: Departments of Otolaryngology, University of Toyama, Japan. hshojaku@med.u-toyama.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Shojaku
authors.forename: Yukio
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Noriaki
authors.initials: N
authors.lastname: Takeda
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ikezono
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takahashi
authors.forename: Akinobu
authors.initials: A
authors.lastname: Kakigi
authors.forename: Juichi
authors.initials: J
authors.lastname: Ito
authors.forename: Katsumi
authors.initials: K
authors.lastname: Doi
authors.forename: Mamoru
authors.initials: M
authors.lastname: Suzuki
authors.forename: Masaya
authors.initials: M
authors.lastname: Takumida
authors.forename: Katsumasa
authors.initials: K
authors.lastname: Takahashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamashita
authors.forename: Izumi
authors.initials: I
authors.lastname: Koizuka
authors.forename: Shinichi
authors.initials: S
authors.lastname: Usami
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Aoki
authors.forename: Hideaki
authors.initials: H
authors.lastname: Naganuma
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D035843:Biomedical Research; D002648:Child; D002675:Child, Preschool; D003638:Deafness / Q000453:epidemiology* / Q000209:etiology; D018159:Endolymphatic Hydrops / Q000150:complications / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult