Profile of asymmetrical retinopathy of prematurity in twins.
BACKGROUND
In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors.


OBJECTIVE
To study the profile of asymmetric ROP in twins


METHODS
Retrospective study.


METHODS
Tertiary ROP referral eye hospital.


METHODS
The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome.


RESULTS
In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course.


CONCLUSIONS
Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.
Azad
Rajvardhan
R
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110 029, India.
Chandra
Parijat
P
Patwardhan
Sourabh D
SD
Gupta
Aparna
A
D004200:Diseases in Twins / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000235:genetics