A case of acute q Fever with severe acute cholestatic hepatitis.
Minimal hepatic dysfunction can be common in acute Q fever, but severe acute cholestatic hepatitis is rarely reported. We report on a 55-year-old male with acute Q fever and severe acute cholestatic hepatitis. He complained of fever, jaundice, ascites, and restlessness on admission. A liver biopsy revealed the presence of compact fibrin-ring granulomas. Serologic titers for C. burnetii IgM and IgG were 2048:1 and 1024:1, respectively. C. burnetii DNA was detected by a nested polymerase chain reaction on the liver tissue.
Choi
Hyun Cheul
HC
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Lee
Sang Hyub
SH
Kim
Junghee
J
Kim
Sung Han
SH
Hwang
Jin-Hyeok
JH
Kim
Jin-Wook
JW
Jeong
Sook-Hyang
SH
Kim
Haeryoung
H