Pecipamide, a new sphingosine derivative from the cultures of Polyporus picipes (Basidiomycetes).
A new C(18)-ceramide congener named pecipamide (1), together with the known ergosta-4,6,8(14),22-tetraen-3-one (2), was isolated from the solid fermentations of the basidiomycetous fungus Polyporus picipes. The structure of the new metabolite was established as (2'R,2S,3R)-N-2'-hydroxyheptadecanoyl-2-amino-octadecane-1,3-diol on the basis of spectroscopic data, including 1D- and 2D- nuclear magnetic resonance spectroscopy (NMR) experiments, as well as by means of mass spectrometric measurements (MS).
Li
Yong
Y
Natural Medicinal Chemistry Research Centre, College of Science, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Ma
Ya-Tuan
YT
Kuang
Yi
Y
Gao
Jin-Ming
JM
Qin
Jian-Chun
JC
D002783:Cholestenones / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D055492:Polyporus / Q000737:chemistry*; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000737:chemistry*
D002783:Cholestenones; C551657:pecipamide; D013110:Sphingosine; C015860:ergosta-4,6,8(14),22-tetraen-3-one