title: Incidence of bloodstream infection among patients on hemodialysis by central venous catheter.
abstract: This study evaluated the incidence and risk factors of bloodstream infection (BSI) among patients with a double-lumen central venous catheter (CVC) for hemodialysis (HD) and identified the microorganisms isolated from the bloodstream. A follow-up included all patients (n=156) who underwent hemodialysis by double-lumen CVC at the Federal University of São Paulo-UNIFESP, Brazil, over a one-year period. From the group of patients, 94 presented BSI, of whom 39 had positive cultures at the central venous catheter insertion location. Of the 128 microorganisms isolated from the bloodstream, 53 were S. aureus, 30 were methicillin-sensitive and 23 were methicillin-resistant. Complications related to BSI included 35 cases of septicemia and 27 cases of endocarditis, of which 15 cases progressed to death. The incidence of BSI among these patients was shown to be very high, and this BSI progressed rapidly to the condition of severe infection with a high mortality rate.
authors.affiliation: Departamento de Enfermagem, Universidade Federal de São Paulo, Brazil. cibelegrothe@hotmail.com.br
authors.forename: Cibele
authors.initials: C
authors.lastname: Grothe
authors.forename: Angélica Gonçalves
authors.initials: AG
authors.lastname: da Silva Belasco
authors.forename: Ana Rita
authors.initials: AR
authors.lastname: de Cássia Bittencourt
authors.forename: Lucila Amaral Carneiro
authors.initials: LA
authors.lastname: Vianna
authors.forename: Ricardo
authors.initials: R
authors.lastname: de Castro Cintra Sesso
authors.forename: Dulce Aparecida
authors.initials: DA
authors.lastname: Barbosa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D004697:Endocarditis, Bacterial / Q000209:etiology* / Q000382:microbiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D012307:Risk Factors; D018805:Sepsis / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology / Q000401:mortality