[Post-operative radiochemotherapy of the head and neck: Towards new standards?].
Head and neck squamous cell carcinomas are frequently diagnosed at an advanced stage. Their treatment remains controversial, and has to be multidisciplinary. External beam radiotherapy is a recognized treatment option after radical curative surgery in order to improve local control. Different adjuvant treatment options have been studied in order to improve the outcome of these patients. We review in this paper the different prognostic factors indicating an adjuvant treatment and the interest of treatment intensification in bad prognostic patients.
Zouhair
A
A
centre hospitalier universitaire vaudois, Lausanne, Suisse. Abderrahim.Zouhair@chuv.ch
Matzinger
O
O
Azria
D
D
Gaye
M P
MP
Ugurluer
G
G
El Hfid
M
M
Mirimanoff
R O
RO
Ozsahin
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control / Q000532:radiotherapy; D010166:Palliative Care; D011184:Postoperative Period; D011379:Prognosis; D018714:Radiotherapy, Adjuvant / Q000592:standards*; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D016879:Salvage Therapy; D016896:Treatment Outcome