title: UK Renal Registry 12th Annual Report (December 2009): chapter 4: UK ESRD prevalent rates in 2008: national and centre-specific analyses.
abstract: BACKGROUND
  This chapter describes the characteristics of adult patients on renal replacement therapy (RRT) in the UK in 2008 and the prevalence rate per million population (pmp) in Primary Care Trusts and local authorities (Council Areas or District Councils) (PCT/LAs) were calculated.
  
  
  METHODS
  Complete data were electronically collected from all 72 renal centres within the UK. A series of cross-sectional and longitudinal analyses were performed to describe the demographics of prevalent RRT patients in 2008 at centre and national level in the UK. Age and gender standardised ratios of actual to expected for prevalence rates in PCT/LAs were calculated.
  
  
  RESULTS
  There were 47,525 adult patients receiving RRT in the UK on 31/12/2008, equating to a UK prevalence of 774 pmp. This represents an annual increase in prevalence of approximately 4.4% although there was significant variation between PCT/LA areas. The pmp growth rate from 2007 to 2008 for prevalent patients by treatment modality in the UK was 5.9% for haemodialysis (HD), a fall of 9.2% for peritoneal dialysis (PD) and growth of 4.6% with a functioning transplant. Over the long term (1982-2007), the steady growth in transplant prevalent numbers was maintained at 4%. There was a slow but steady decline in PD patient numbers from 1999 onwards. Median RRT vintage was 5.3 years. The median age of prevalent patients was 57.3 years (HD 65.5 years, PD 61.0 years and transplant 50.4 years). For all ages, prevalence rates in males exceeded those in females peaking in the 75-79 years age group at 2,582 pmp for males and 70-74 years age group at 1,408 pmp for females. The most common identifiable renal diagnosis was biopsy-proven glomerulonephritis (16.0%), followed by diabetes (14.1%). Transplantation was the most common treatment modality (47%) followed closely by HD (43%). However, HD was increasingly common with increasing older age at the expense of transplantation.
  
  
  CONCLUSIONS
  The HD and transplant population continued to expand whilst the PD population contracted. There was national, regional and dialysis centre level variation in prevalence rates. This has implications for service planning and ensuring equity of care for RRT patients.
authors.affiliation: Nottingham University Hospital, Nottingham, UK. catherine.byrne@nuh.nhs.uk
authors.forename: Catherine
authors.initials: C
authors.lastname: Byrne
authors.forename: Retha
authors.initials: R
authors.lastname: Steenkamp
authors.forename: Clare
authors.initials: C
authors.lastname: Castledine
authors.forename: David
authors.initials: D
authors.lastname: Ansell
authors.forename: John
authors.initials: J
authors.lastname: Feehally
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000847:Annual Reports as Topic; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic / Q000639:trends*; D015995:Prevalence; D012042:Registries; D017582:Renal Replacement Therapy / Q000639:trends; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult