title: Seroprevalence of orthopoxvirus in an Amazonian rural village, Acre, Brazil.
abstract: Vaccinia virus strains from the family Poxviridae have been frequently isolated in Brazil and associated with outbreaks of exanthematic disease affecting cows and humans. An ELISA IgG was applied to evaluate the seroprevalence of orthopoxviruses in a community located in a rural settlement in the Amazon region, where no orthopoxvirus outbreaks have yet been reported. An overall seroprevalence of 27.89% was found, and it was 23.38% in the non-vaccinated population (smallpox vaccination). These results strongly suggest that orthopoxviruses circulate in this population, and it is the first finding of seropositivity for orthopoxviruses in a population without any previously reported outbreaks.
authors.affiliation: Laboratorio de Virus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, Brazil.
authors.forename: B E F
authors.initials: BE
authors.lastname: Mota
authors.forename: G S
authors.initials: GS
authors.lastname: Trindade
authors.forename: T C
authors.initials: TC
authors.lastname: Diniz
authors.forename: M
authors.initials: M
authors.lastname: da Silva-Nunes
authors.forename: E M
authors.initials: EM
authors.lastname: Braga
authors.forename: M
authors.initials: M
authors.lastname: Urbano-Ferreira
authors.forename: G O L
authors.initials: GO
authors.lastname: Rodrigues
authors.forename: C A
authors.initials: CA
authors.lastname: Bonjardim
authors.forename: P C P
authors.initials: PC
authors.lastname: Ferreira
authors.forename: E G
authors.initials: EG
authors.lastname: Kroon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D018155:Orthopoxvirus / Q000276:immunology*; D011213:Poxviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D012307:Risk Factors; D012424:Rural Population; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G