Compliance and persistence with osteoporosis medications: a critical review of the literature.
It is widely acknowledged that compliance and persistence with oral osteoporosis medications, particularly with bisphosphonates, is poor. Several excellent reviews have been written on compliance and persistence with osteoporosis medications and have discussed improvements seen with extended dosing intervals. This review begins with studies on extended dosing intervals to examine the limitations of administrative claims data. It also looks at compliance and persistence across multiple medical conditions, examining the importance of prescription fulfillment, intentional choice, causation and possible interventions.
Silverman
Stuart
S
Cedars-Sinai/UCLA, 8641 Wilshire Blvd., Suite 301, Beverly Hills, CA 90211, USA. stuarts@omcresearch.org
Gold
Deborah T
DT
D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D006801:Humans; D055118:Medication Adherence; D010024:Osteoporosis / Q000188:drug therapy*
D050071:Bone Density Conservation Agents