Risk factors for bacteremia with uropathogen not cultured from urine in adults with febrile urinary tract infection.
In a prospective study involving 642 patients with febrile urinary tract infection (UTI), we found antimicrobial pretreatment (odds ratio [OR], 3.3), an indwelling urinary catheter (OR, 2.8), and malignancy (OR, 2.7) to be independent risk factors for bacteremia with a uropathogen that was not cultured or recognized in the urine. Although the diagnostic value of blood cultures has been questioned in UTI, we advocate performing blood cultures for patients with these risk factors.
van Nieuwkoop
Cees
C
Departments of Infectious Diseases , Bronovo Hospital, the Netherlands. c.van_nieuwkoop@lumc.nl
Bonten
Tobias N
TN
Wout
Jan W Van't
JW
Becker
Martin J
MJ
Groeneveld
Geert H
GH
Jansen
Casper L
CL
van der Vorm
Eric R
ER
Ijzerman
Ed P
EP
Rothbarth
Philip H
PH
Termeer-Veringa
Etel M
EM
Kuijper
Ed J
EJ
van Dissel
Jaap T
JT
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000453:epidemiology*; D002408:Catheters, Indwelling / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D011446:Prospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000150:complications* / Q000382:microbiology; D014556:Urine / Q000382:microbiology*; D055815:Young Adult
D000900:Anti-Bacterial Agents