title: Longitudinal right ventricular function as a predictor of functional capacity in patients with mitral stenosis: an exercise echocardiographic study.
abstract: BACKGROUND
  The influence of right ventricular (RV) function on exercise capacity has been poorly explored in mitral stenosis (MS). The objective of this study was to assess the determinants of functional status with exercise echocardiography in MS.
  
  
  METHODS
  Thirty-nine patients (55 +/- 12 years, 29 female) with MS (1.3 +/- 0.5 cm(2)) underwent an exercise echocardiography (14 patients had previous balloon valvuloplasty). RV function was assessed by tricuspid annulus S-wave velocity (Tric-S) and tricuspid annular plane systolic excursion (TAPSE).
  
  
  RESULTS
  Tric-S correlated with TAPSE (P = .03), cardiac output (P = .006), and mitral valve area (P = .009). With exercise, Tric-S and TAPSE increased significantly (11.3 +/- 3.1 cm/s to 15.5 +/- 3.4 cm/s and 21.2 +/- 5.2 mm to 24.0 +/- 5.8 mm, respectively, both P < .05). TAPSE was lower in patients in New York Heart Association class 3 or 4. In multivariate analysis, Tric-S at rest (beta = 0.34, P = .006) and mitral Delta mean diastolic gradient (beta = 0.34, P = .006) were the independent determinants of maximum workload.
  
  
  CONCLUSIONS
  Resting RV longitudinal function assessed through Tric-S is an important determinant of functional capacity in MS.
authors.affiliation: Service d'Explorations Fonctionnelles, Cardiology University Hospital, CHRU, Lille, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Deswarte
authors.forename: Marjorie
authors.initials: M
authors.lastname: Richardson
authors.forename: Anne Sophie
authors.initials: AS
authors.lastname: Polge
authors.forename: Sébastien
authors.initials: S
authors.lastname: Pouwels
authors.forename: Pierre Vladimir
authors.initials: PV
authors.lastname: Ennezat
authors.forename: Jean-Noël
authors.initials: JN
authors.lastname: Trochu
authors.forename: Benoit
authors.initials: B
authors.lastname: Wallaert
authors.forename: Ghislaine
authors.initials: G
authors.lastname: Deklunder
authors.forename: Thierry
authors.initials: T
authors.lastname: Le Tourneau
mesh_terms: D000328:Adult; D025401:Echocardiography, Stress; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016278:Ventricular Function, Right