title: Cosmeceuticals: the evidence behind the retinoids.
abstract: A wide range of cosmeceutical products are available on the market currently, but evidence to support their use is often lacking in the literature. Specifically, there is a substantial amount of evidence supporting the efficacy of tretinoin in photoaging, but the evidence supporting retinoid-based cosmeceuticals remains sparse. The authors review the current data in the literature related to vitamin A-derived cosmeceutical products and conclude that cosmeceuticals containing retinaldehyde have been shown in large randomized, controlled trials to have the most beneficial effect on aging skin.
authors.affiliation: Wrightington, Wigan and Leigh NHS Foundation Trust, UK.
authors.forename: Kajal
authors.initials: K
authors.lastname: Babamiri
authors.forename: Reza
authors.initials: R
authors.lastname: Nassab
mesh_terms: D000287:Administration, Topical; D000975:Antioxidants / Q000627:therapeutic use; D003358:Cosmetics / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004224:Diterpenes; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012172:Retinaldehyde / Q000627:therapeutic use; D012176:Retinoids / Q000627:therapeutic use*; D000084562:Retinyl Esters; D015595:Skin Aging / Q000187:drug effects*; D014212:Tretinoin / Q000627:therapeutic use; D014801:Vitamin A / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D003879:Dermatologic Agents; D004224:Diterpenes; D007641:Keratolytic Agents; D012176:Retinoids; D000084562:Retinyl Esters; D014801:Vitamin A; C014794:retinol palmitate; C009166:retinol acetate; D014212:Tretinoin; D012172:Retinaldehyde