title: New MR sequences (diffusion, perfusion, spectroscopy) in brain tumours.
abstract: While MRI has been instrumental in significantly improving care in children harbouring brain tumours, conventional sequences lack information regarding functional parameters including cellularity, haemodynamics and metabolism. Advanced MR imaging modalities, such as diffusion (including diffusion tensor imaging and fibre tractography), perfusion and spectroscopy have significantly improved our understanding of the physiopathology of brain tumours and have provided invaluable additional information for treatment planning and monitoring of treatment results. The contribution of these methods to the characterization of brain neoplasms in children is the focus of the present manuscript.
authors.affiliation: Pediatric Neuroradiology, G. Gaslini Children's Research Hospital, Largo G Gaslini 5, Genova 16147, Italy. andrearossi@ospedale-gaslini.ge.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Rossi
authors.forename: Carlo
authors.initials: C
authors.lastname: Gandolfo
authors.forename: Giovanni
authors.initials: G
authors.lastname: Morana
authors.forename: Mariasavina
authors.initials: M
authors.lastname: Severino
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Garrè
authors.forename: Armando
authors.initials: A
authors.lastname: Cama
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods* / Q000639:trends*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D014408:Biomarkers, Tumor