title: A novel diastereoselective multicomponent cascade reaction.
abstract: A novel multicomponent cascade reaction led to the formation of a strained 3-azabicyclo[3.2.0]heptane derivative 4. The unstable ester 4 was reduced in a one-pot procedure to a stable alcohol 6. The formation of the bicyclic product is highly diastereoselective, predominantly affording one diastereoisomer. The obtained azabicycloheptanes are important pharmacophores.
authors.affiliation: Department of Chemistry, Tallinn University of Technology, Akadeemia tee 15, 12618 Tallinn, Estonia, and National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618 Tallinn, Estonia.
authors.forename: Kadri
authors.initials: K
authors.lastname: Kriis
authors.forename: Kerti
authors.initials: K
authors.lastname: Ausmees
authors.forename: Tõnis
authors.initials: T
authors.lastname: Pehk
authors.forename: Margus
authors.initials: M
authors.lastname: Lopp
authors.forename: Tõnis
authors.initials: T
authors.lastname: Kanger