title: [Effect of alcohol concentration in water extraction and alcohol precipitation on preparation of effervescent tablets of Banlangen].
abstract: OBJECTIVE
  To study effect of alcohol concentration in water extraction and alcohol precipitation on the preparation of effervescent tablets of Banlangen.
  
  
  METHODS
  Effects of different concentrations of alcohol precipitation on the Banlangen extract rate, metastasis rate of index components, extract properties of powder, preparation process were investigated, respectively.
  
  
  RESULTS
  Alcohol concentration on the Banlangen extract rate, metastasis rate of adenosine, extract the amount of saturated moisture, effervescent disintegration time of no significant impact, but spray drying process, dry granulation process.
  
  
  CONCLUSIONS
  Alcohol concentration has a significant effect on the preparation of effervescent tablets of Banlangen in the process of water extraction and alcohol precipitation, It suggest that the choice of concentration of alcohol precipitation should be based on experimental purposes, the entire preparation process of the system test results.
authors.affiliation: National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China. heyan95@yahoo.com.cn
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Hongliang
authors.initials: H
authors.lastname: Xin
authors.forename: Kai
authors.initials: K
authors.lastname: Huang
authors.forename: Yao
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiaojian
authors.initials: X
authors.lastname: Luo
mesh_terms: D011232:Chemical Precipitation; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry*; D013607:Tablets / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014867:Water / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D013607:Tablets; D014867:Water; D000431:Ethanol; C540579:banlangen