Cohort study finds nine times increased overdose risk (fatal plus non-fatal) in patients receiving 100 mg/day for 90 days compared with 1-20 mg/day opioids for chronic non-cancer pain, but wide CI and possibility of unmeasured confounders.
Hochman
Joel Simon
JS
National Foundation for the Treatment of Pain, Houston, Texas 770099, USA. jfshmd@gmail.com
Pergolizzi
Joe
J