title: Alpha-arylation of 3-aryloxindoles.
abstract: A versatile method for the synthesis of 3,3-diaryloxindoles via Pd-catalyzed alpha-arylations or an S(N)Ar reaction is described. The reaction proceeds using mild base, is tolerant of a variety of functional groups, and is capable of preparing hindered all-carbon quaternary centers.
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215, USA.
authors.forename: Cheng-Kang
authors.initials: CK
authors.lastname: Mai
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Sammons
authors.forename: Tarek
authors.initials: T
authors.lastname: Sammakia
mesh_terms: D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D009942:Organometallic Compounds; D010165:Palladium