title: Diastereoselective Synthesis of trans-beta-Lactams Using a Simple Multifunctional Catalyst.
abstract: A catalytic, highly diastereoselective process for the synthesis of trans-beta-lactams is reported. This system is based on a phosphonium fluoride precatalyst that both activates the nucleophile and directs the reaction process for high yield and diastereoselectivity.
authors.affiliation: Department of Chemistry, New Chemistry Building, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.
authors.forename: Ciby J
authors.initials: CJ
authors.lastname: Abraham
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Paull
authors.forename: Cajetan
authors.initials: C
authors.lastname: Dogo-Isonagie
authors.forename: Thomas
authors.initials: T
authors.lastname: Lectka