title: Group-based psychosocial intervention for bipolar disorder: randomised controlled trial.
abstract: BACKGROUND
  Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder.
  
  
  OBJECTIVE
  To evaluate a manualised group-based intervention for people with bipolar disorder in a naturalistic setting.
  
  
  METHODS
  Eighty-four participants were randomised to receive the group-based intervention (a 12-week programme plus three booster sessions) or treatment as usual, and followed up with monthly telephone interviews (for 9 months post-intervention) and face-to-face interviews (at baseline, 3 months and 12 months).
  
  
  RESULTS
  Participants who received the group-based intervention were significantly less likely to have a relapse of any type and spent less time unwell. There was a reduced rate of relapse in the treatment group for pooled relapses of any type (hazard ratio 0.43, 95% CI 0.20-0.95; t(343) = -2.09, P = 0.04).
  
  
  CONCLUSIONS
  This study suggests that the group-based intervention reduces relapse risk in bipolar disorder.
authors.affiliation: Department of Psychiatry, University of Melbourne, and St Vincent's Health, Fitzroy 3065, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Castle
authors.forename: Carolynne
authors.initials: C
authors.lastname: White
authors.forename: James
authors.initials: J
authors.lastname: Chamberlain
authors.forename: Michael
authors.initials: M
authors.lastname: Berk
authors.forename: Lesley
authors.initials: L
authors.lastname: Berk
authors.forename: Sue
authors.initials: S
authors.lastname: Lauder
authors.forename: Greg
authors.initials: G
authors.lastname: Murray
authors.forename: Isaac
authors.initials: I
authors.lastname: Schweitzer
authors.forename: Leon
authors.initials: L
authors.lastname: Piterman
authors.forename: Monica
authors.initials: M
authors.lastname: Gilbert
mesh_terms: D000328:Adult; D018692:Antimanic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000517:prevention & control / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011615:Psychotherapy, Group / Q000379:methods*; D055502:Secondary Prevention; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D018692:Antimanic Agents