Carbon nanotube-based neurochips.
High-density carbon nanotube (CNT)-coated surfaces are highly neuro-adhesive. When shaped into regular arrays of isolated islands on a non-adhesive support substrate (such as a clean glass), CNTs can function as effective encoring sites for neurons and glia cells for in-vitro applications. Primarily, patterned CNT islands provide a means to form complex, engineered, interconnected neuronal networks with pre-designed geometry via utilizing the self-assembly process of neurons. Depositing these CNT islands onto multielectrode array chip can facilitate both cell anchoring but also electrical interfacing between the electrodes and the neurons.
David-Pur
Moshe
M
School of Electrical Engineering, Tel-Aviv University, Tel-Aviv, Israel.
Shein
Mark
M
Hanein
Yael
Y
D000818:Animals; D002478:Cells, Cultured; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D046228:Microarray Analysis; D008839:Microelectrodes; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009457:Neuroglia / Q000737:chemistry* / Q000166:cytology; D009474:Neurons / Q000737:chemistry* / Q000166:cytology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013499:Surface Properties
D020099:Coated Materials, Biocompatible; D037742:Nanotubes, Carbon