Practices in peptic ulcer bleeding controversies among university- versus nonuniversity-affiliated gastroenterologists.
BACKGROUND
Practices relating to acute peptic ulcer bleeding (APUB) outside of guideline recommendations are unknown.


OBJECTIVE
To evaluate the practices of university-affiliated (UA) versus nonuniversity-affiliated (non-UA) gastroenterologists in controversial APUB issues.


METHODS
Gastroenterologists in Canada were mailed an anonymous questionnaire (January 2008) regarding APUB management.


RESULTS
Responses were received for 281 of the 530 questionnaires mailed (53%). There were no differences between the UA versus non-UA gastroenterologists regarding acid suppression medication and route of administration pre- and postendoscopy (all P>0.05). There were no differences in endoscopic practices between groups regarding large versus small volume injection, endoclip versus combination injection plus coagulation, endoclip versus endoclip plus injection, and management of adherent clots (all P>0.05). There was variability within each group regarding optimal empirical acid suppression pre- and postendoscopy, volume of injection therapy and endoclip use. The non-UA group had longer delays before restarting acetylsalicyclic acid (P=0.08) and warfarin (P=0.02) post-APUB.


CONCLUSIONS
UA and non-UA gastroenterologists have similar practices in acid suppression and endoscopic therapy for controversial APUB issues; however, non-UA gastroenterologists appear more cautious in restarting acetylsalicylic acid and warfarin. Further studies are needed to address the optimal empirical acid suppression pre- and postendoscopy, injection therapy volume, endoclip use, and timing of restarting antiplatelet and anticoagulation therapy.
Cheung
Justin
J
Department of Medicine, Division of Gastroenterology, University of Alberta, University of Alberta Hospital, Edmonton, Alberta.
Sawisky
Grant
G
Enns
Robert
R
Byrne
Michael F
MF
Zhu
Qiaohao
Q
Wong
Clarence K W
CK
D000046:Academic Medical Centers; D002983:Clinical Competence; D004381:Duodenal Ulcer / Q000628:therapy*; D005762:Gastroenterology / Q000379:methods*; D006489:Hemostatic Techniques / Q000706:statistics & numerical data*; D006782:Hospitals, Special; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods; D010438:Peptic Ulcer Hemorrhage / Q000628:therapy*; D012189:Retrospective Studies; D013276:Stomach Ulcer / Q000628:therapy*