Synthesis of 4- and 4,5-functionalized imidazol-2-ylidenes from a single 4,5-unsubstituted imidazol-2-ylidene.
Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon-carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
Mendoza-Espinosa
Daniel
D
UCR-CNRS Joint Research Chemistry Laboratory (UMR 2282), Department of Chemistry, University of California, Riverside, California 92521-0403, USA.
Donnadieu
Bruno
B
Bertrand
Guy
G
D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D007093:Imidazoles / Q000138:chemical synthesis*; D008697:Methane / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D006571:Heterocyclic Compounds; D007093:Imidazoles; C030011:carbene; D008697:Methane