title: Severe manifestation of oral pemphigus.
abstract: This article describes a case of pemphigus vulgaris in a relatively young patient with exacerbated characteristics, widespread lesions, and rapid evolution. A 40-year-old woman sought treatment, complaining about severe oral pain and dysphagia. Intraoral inspection revealed ulcerated lesions on the lips, buccal mucosa, and floor of the mouth. The number of lesions quickly increased and resembled erythema multiforme. She also presented blistering lesions on the back, abdomen, neck, and eyes. Incisional oral biopsy revealed pemphigus vulgaris. This report emphasizes the importance of early diagnosis of an oral biopsy in systemic diseases and the management of the lesions.
authors.affiliation: Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Al. Dr Otávio Pinheiro Brisolla 9-75, Bauru, SP, Brazil.
authors.forename: Etiene de Andrade
authors.initials: Ede A
authors.lastname: Munhoz
authors.forename: Camila Lopes
authors.initials: CL
authors.lastname: Cardoso
authors.forename: Jaison Antônio
authors.initials: JA
authors.lastname: Barreto
authors.forename: Cleverson Teixeira
authors.initials: CT
authors.lastname: Soares
authors.forename: José Humberto
authors.initials: JH
authors.lastname: Damante
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009059:Mouth Diseases / Q000175:diagnosis*; D009061:Mouth Mucosa / Q000473:pathology*; D010392:Pemphigus / Q000175:diagnosis*; D012720:Severity of Illness Index