title: Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma.
abstract: OBJECTIVE
  To investigate treatment outcome of Helicobacter pylori (H. pylori)-negative low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma.
  
  
  METHODS
  In this study, we retrospectively reviewed the clinical outcome and clinicopathologic factors of stage IE H. pylori-negative low-grade gastric MALT lymphoma cases from August 1998 to June 2009.
  
  
  RESULTS
  A total of eleven patients with H. pylori-negative low-grade gastric MALT lymphoma were enrolled in the study and received anti-H. pylori eradication treatment and/or radiotherapy or excisional therapy. Complete remission (CR) of gastric MALT lymphoma was achieved in all patients. The time to CR was 1-66 mo (median, 1 mo).
  
  
  CONCLUSIONS
  Eradication therapy may be offered as an initial treatment option even in cases of localized H. pylori-negative gastric MALT lymphoma.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, 120-752 Seoul, South Korea.
authors.forename: Hyung Soon
authors.initials: HS
authors.lastname: Park
authors.forename: Yu Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Woo Ick
authors.initials: WI
authors.lastname: Yang
authors.forename: Chang Ok
authors.initials: CO
authors.lastname: Suh
authors.forename: Yong Chan
authors.initials: YC
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome