title: The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease.
abstract: Backscattering interferometry enables the detection of syphilis antibody-antigen interactions in the presence of human serum, showing promise as a diagnostic tool for the serological diagnosis of infectious disease with potentially quantitative capabilities.
authors.affiliation: Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.
authors.forename: Amanda
authors.initials: A
authors.lastname: Kussrow
authors.forename: Carolyn S
authors.initials: CS
authors.lastname: Enders
authors.forename: Arnold R
authors.initials: AR
authors.lastname: Castro
authors.forename: David L
authors.initials: DL
authors.lastname: Cox
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Ballard
authors.forename: Darryl J
authors.initials: DJ
authors.lastname: Bornhop
mesh_terms: D000906:Antibodies / Q000097:blood / Q000276:immunology; D000941:Antigens / Q000097:blood / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007368:Interferometry / Q000379:methods*; D008027:Light; D013587:Syphilis / Q000097:blood / Q000175:diagnosis*; D013588:Syphilis Serodiagnosis / Q000379:methods*
chemical_list: D000906:Antibodies; D000941:Antigens; D007074:Immunoglobulin G