A 61-year-old woman with osteomalacia and a thoracic spine lesion.
Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative.
Marshall
Ann E
AE
Martin
Sarah E
SE
Agaram
Narasimhan P
NP
Chen
Jey-Hsin
JH
Horn
Eric M
EM
Douglas-Akinwande
Annette C
AC
Hattab
Eyas M
EM
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018193:Neoplasms, Complex and Mixed / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D009372:Neoplasms, Connective Tissue / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D010018:Osteomalacia / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D013125:Spinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D013904:Thoracic Vertebrae