[Endomyocardial disease as the first manifestation of hypereosinophilic syndrome].
A case of hypereosinophilic syndrome (HES) initially manifesting as endomyocardial disease in a 21-year-old man is presented. The diagnosis of HES was made according to the Chusid's criteria. Myeloproliferative disorders were excluded and corticosteroid therapy with prednisone at a dose of 1 mg/kg/d was started immediately. After 30 days of continuous corticotherapy the patient recovered completely. His blood eosinophil count decreased from 8740 cells/microL (48.7%) to 30 cells/microL (0.3%). Then, prednisone was discontinued gradually. During 18-month follow-up the patient was free from cardiovascular symptoms and his complete blood count was normal. We also present the current state of knowledge on the cardiovascular complications of hypereosinophilic syndrome.
Poreba
Małgorzata
M
Klinika Choroby Wiencowej, Instytut Kardiologii, Uniwersytet Jagiellonski, Krakow.
Rostoff
Paweł
P
Konduracka
Ewa
E
Pikul
Patrycja
P
Rucińska
Małgorzata
M
Pasowicz
Mieczysław
M
Piwowarska
Wiesława
W
D000328:Adult; D003937:Diagnosis, Differential; D004719:Endomyocardial Fibrosis / Q000150:complications / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009206:Myocardium / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
D005938:Glucocorticoids; D011241:Prednisone