Stereochemistry of 4-hydroxyproline affects the conformation of conopeptides.
The cis/trans isomerization of 4-hydroxyproline is shown to remarkably affect the conformation of conopeptides with or without disulfide bonds.
Xu
Jia
J
Department of Chemistry, Renmin University of China, Beijing, 100872, China.
Wang
Yanli
Y
Zhang
Bingbing
B
Wang
Baohuai
B
Du
Weihong
W
D006909:Hydroxyproline / Q000737:chemistry*; D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry*; D011487:Protein Conformation; D013237:Stereoisomerism
D010455:Peptides; D006909:Hydroxyproline