title: Response to growth hormone therapy in adolescents with familial panhypopituitarism.
abstract: Familial combined pituitary hormone deficiency is a rare endocrine disorder. We describe growth patterns of four children (3 females and 1 male) from two families with combined pituitary hormone deficiency. These children received growth hormone at ages ranging from 14.5 years to 19 years. While all the female siblings reached their target height, the male sibling was much shorter than mid parental height. The reasons for sexual dimorphism in growth patterns in these children are unclear.
authors.affiliation: Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, Delhi, India.
authors.forename: B
authors.initials: B
authors.lastname: Kulshreshtha
authors.forename: M
authors.initials: M
authors.lastname: Eunice
authors.forename: A C
authors.initials: AC
authors.lastname: Ammini
mesh_terms: D000293:Adolescent; D001827:Body Height / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D008297:Male; D055815:Young Adult
chemical_list: D013006:Growth Hormone