title: Current strategies for nonsurgical, arthroscopic, and minimally invasive surgical treatment of knee cartilage pathology.
abstract: The current approaches to treating articular cartilage defects in the knee comprise a spectrum from pharmacologic therapies to total knee arthroplasty. Nonsurgical treatment can include anti-inflammatory medications, bracing, and physical therapy. Surgical treatments include reconstructive repair of a small or large defect using microfracture, osteochondral autograft transplantation, autologous chrondrocyte transplantation, or osteochondral allograft transplantation; realignment procedures including osteotomies; and unicompartmental arthroplasty. A comprehensive algorithm can be used to determine the appropriate treatment for knee defects.
authors.affiliation: Department of Orthopaedics, North Shore-Long Island Jewish Medical Center, Manhasset, New York, USA.
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Sgaglione
authors.forename: Eli
authors.initials: E
authors.lastname: Chen
authors.forename: Jack M
authors.initials: JM
authors.lastname: Bert
authors.forename: Annunziato
authors.initials: A
authors.lastname: Amendola
authors.forename: William D
authors.initials: WD
authors.lastname: Bugbee
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D054544:Arthroplasty, Subchondral; D001182:Arthroscopy; D016025:Bone Transplantation; D002357:Cartilage Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D002358:Cartilage, Articular; D006801:Humans; D008592:Menisci, Tibial; D020370:Osteoarthritis, Knee / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D055676:Viscosupplementation
chemical_list: D000893:Anti-Inflammatory Agents