Outcome of Iranian children with mild post streptococcal glomerulonephritis.
We studied the long-term outcome of children with mild acute post streptococcal glomerulonephritis (APSGN) APSGN hospitalized at St. Al Zahra hospital, Isfahan, Iran from 1993-1998. The patients were subdivided into two groups according to the duration of follow-up. Group A consisted of 15 patients and group B consisted of 12 patients, followed up for 4 and 8 years, respectively. The male to female ratio was 1.45/1. The mean GFR in group A and B was 127.7 +/- 26 mL/min/1.73 m2 and 128.57 +/- 7 mL/min/1.73 m2, respectively. There was no statistically significant difference between GFRs in two groups. Comparing the mean systolic blood pressure in two groups did not demonstrate a significant difference; 95.33 +/- 7.1 mmHg in group A and 102.5 +/- 14.06 mmHg in group B. However the mean diastolic blood pressure in group B was significantly higher than group A; 65.4 +/- 11.71 mmHg vs 61.33 +/- 3.51 mmHg. Our study found that even mild APSGN may lead to some degree of renal impairment, and rising diastolic blood pressure maybe an early clinical sign of renal impairment in APSGN.
Gheissari
Alaleh
A
Pediatric Nephrology Department, St. Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. gheisari@med.mui.ac.ir
Adjodani
Taj Saadat
TS
Hashemi
Maryam
M
Mokhtarian
Arghavan
A
Sirous
Mehri
M
D000208:Acute Disease; D000293:Adolescent; D001794:Blood Pressure; D018450:Disease Progression; D005260:Female; D005919:Glomerular Filtration Rate; D005921:Glomerulonephritis / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007492:Iran; D008297:Male; D012720:Severity of Illness Index; D013290:Streptococcal Infections / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome