title: [Fatal pneumonia with Panton Valentine leucocidin-producing Staphylococcus aureus].
abstract: We describe a case of fatal pneumonia in a previously healthy 14-year-old boy. The patient was severely affected at the time of admission with high fever, tachypnea, tachycardia and peripheral cyanosis. The condition worsened despite treatment with antibiotics as well as respiratory and pressure support. Acidosis and critical leucopenia supervened and the patient died just short of 24 hours after admission. Subsequent bacterial cultivation showed Panton-Valentine Leucocidin-producing Staphylococcus aureus.
authors.affiliation: Paediatrisk Afdeling, Nykøbing Falster Sygehus, DK-4800 Nykøbing Falster, Denmark. peterraboel@hotmail.com
authors.forename: Peter Hedelund
authors.initials: PH
authors.lastname: Rabøl
authors.forename: Ram Benny
authors.initials: RB
authors.lastname: Dessau
authors.forename: Mads
authors.initials: M
authors.lastname: Warnecke
authors.forename: Lise
authors.initials: L
authors.lastname: Bjerglund
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001427:Bacterial Toxins / Q000096:biosynthesis*; D004630:Emergencies; D005098:Exotoxins / Q000096:biosynthesis*; D017809:Fatal Outcome; D006801:Humans; D007956:Leukocidins / Q000096:biosynthesis*; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008297:Male; D009336:Necrosis; D011023:Pneumonia, Staphylococcal / Q000382:microbiology* / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin