title: Cerebral malformations without antenatal diagnosis.
abstract: Cerebral malformations are usually described following the different steps in development. Disorders of neurulation (dysraphisms), or diverticulation (holoprosencephalies and posterior fossa cysts), and total commissural agenesis are usually diagnosed in utero. In contrast, disorders of histogenesis (proliferation-differentiation, migration, organization) are usually discovered in infants and children. The principal clinical symptoms that may be a clue to cerebral malformation include congenital hemiparesis, epilepsy and mental or psychomotor retardation. MRI is the imaging method of choice to assess cerebral malformations.
authors.affiliation: Diagnostic Neuroradiology, Hôpital Timone, 264 Rue Saint Pierre, 13385 Marseille cedex 5, France. nadine.girard@ap-hm.fr
authors.forename: Nadine J
authors.initials: NJ
authors.lastname: Girard
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D002538:Intracranial Arteriovenous Malformations / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011296:Prenatal Diagnosis