Characterization of JadH as an FAD- and NAD(P)H-dependent bifunctional hydroxylase/dehydrase in jadomycin biosynthesis.
Chen
Yihua
Y
Division of Pharmaceutical Sciences,University of Wisconsin, Madison, WI 53705 78, USA.
Fan
Keqiang
K
He
Yongzhi
Y
Xu
Xinping
X
Peng
Yanfeng
Y
Yu
Tingting
T
Jia
Cuijuan
C
Yang
Keqian
K
D004926:Escherichia coli / Q000235:genetics; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D015870:Gene Expression; D007546:Isoquinolines / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000235:genetics / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D009285:Naphthoquinones / Q000378:metabolism*; D013302:Streptomyces / Q000201:enzymology* / Q000378:metabolism
D007546:Isoquinolines; D009285:Naphthoquinones; C506597:jadomycin A; D005182:Flavin-Adenine Dinucleotide; C081750:jadomycin B; D009249:NADP; D006899:Mixed Function Oxygenases