title: Congenital vitamin D deficiency: a rare etiology of an acute life threatening event in early infancy.
abstract: Infants born to mothers with deficiency of vitamin D and/or calcium due to cultural modifications in their diets, life style and clothing habits, are at risk of developing early and fatal sequelae of hypocalcemic vitamin D deficiency. We present a 44-day-old infant with hypocalcemia secondary to congenital vitamin D deficiency, who presented as a recurrent Acute Life Threatening Event (ALTE) resulting in an unexpectedly prolonged intensive care course. This report suggests that evaluation of vitamin D status should be included as part of the workup of ALTE and we describe evidence-based preventive measures for both mothers and infants who are at risk for vitamin D deficiency.
authors.affiliation: Department of Pediatrics, Medical College Umm Al-Qura University, Makkah, Saudi Arabia. rafatmosali@hotmail.com
authors.forename: Rafat
authors.initials: R
authors.lastname: Mosalli
authors.forename: Elsayed
authors.initials: E
authors.lastname: Yasser
authors.forename: Abbass Mohammad
authors.initials: AM
authors.lastname: Ali
authors.forename: Saleh
authors.initials: S
authors.lastname: Al Harbi
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D002112:Calcifediol / Q000008:administration & dosage / Q000097:blood; D002118:Calcium / Q000008:administration & dosage / Q000097:blood; D003422:Critical Care; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000097:blood / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena; D015278:Intensive Care Units, Pediatric; D007902:Length of Stay; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D011247:Pregnancy; D012008:Recurrence; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014808:Vitamin D Deficiency / Q000097:blood / Q000151:congenital* / Q000503:physiopathology / Q000628:therapy; D014815:Vitamins / Q000008:administration & dosage
chemical_list: D015415:Biomarkers; D014815:Vitamins; D002112:Calcifediol; D002118:Calcium