title: Random lasing in bone tissue.
abstract: Owing to the low-loss and high refractive index variations derived from the basic building block of bone structure, we, for the first time to our knowledge, demonstrate coherent random lasing action originated from the bone structure infiltrated with laser dye, revealing that bone tissue is an ideal biological material for random lasing. Our numerical simulation shows that random lasers are extremely sensitive to subtle structural changes even at nanoscales and can potentially be an excellent tool for probing nanoscale structural alterations in real time as a novel spectroscopic modality.
authors.affiliation: Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA.
authors.forename: Qinghai
authors.initials: Q
authors.lastname: Song
authors.forename: Shumin
authors.initials: S
authors.lastname: Xiao
authors.forename: Zhengbin
authors.initials: Z
authors.lastname: Xu
authors.forename: Jingjing
authors.initials: J
authors.lastname: Liu
authors.forename: Xuanhao
authors.initials: X
authors.lastname: Sun
authors.forename: Vladimir
authors.initials: V
authors.lastname: Drachev
authors.forename: Vladimir M
authors.initials: VM
authors.lastname: Shalaev
authors.forename: Ozan
authors.initials: O
authors.lastname: Akkus
authors.forename: Young L
authors.initials: YL
authors.lastname: Kim
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000528:radiation effects*; D002417:Cattle; D004396:Coloring Agents; D005240:Feasibility Studies; D007834:Lasers
chemical_list: D004396:Coloring Agents