title: Investigating the function of CAF1 deadenylases during plant stress responses.
abstract: Alteration of gene expression plays a central role in the transmission of developmental and environmental signals. The steady-state transcript level within a cell is determined by the combination of the rate synthesis and the rate of degradation. While altering the rate of mRNA turnover is known to provide a rapid mechanism to reprogram transcript levels, research has largely focused on changes in transcriptional regulation as a mechanism to control mRNA levels. However, recent studies have begun to explore the role of mRNA decay in reprogramming the transcriptome.
authors.affiliation: Division of Biological Sciences, University of California, La Jolla, CA, USA.
authors.forename: Justin W
authors.initials: JW
authors.lastname: Walley
authors.forename: Dior R
authors.initials: DR
authors.lastname: Kelley
authors.forename: Tatyan
authors.initials: T
authors.lastname: Savchenko
authors.forename: Katayoon
authors.initials: K
authors.lastname: Dehesh
mesh_terms: D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D003517:Cyclopentanes / Q000032:analysis; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D054883:Oxylipins / Q000032:analysis; D000072260:RNA Splicing Factors; D020871:RNA Stability; D012260:Ribonucleases / Q000235:genetics / Q000378:metabolism; D013312:Stress, Physiological; D014158:Transcription, Genetic
chemical_list: D029681:Arabidopsis Proteins; C518085:At2g20020 protein, Arabidopsis; D003517:Cyclopentanes; D054883:Oxylipins; D000072260:RNA Splicing Factors; C011006:jasmonic acid; D012260:Ribonucleases; C445084:mRNA deadenylase