title: [Effect of Coflex interspinous stabilization and vertebral arch pedicle screw implantation on the stability of three-dimensional motions of the lumbar spine].
abstract: OBJECTIVE
  To evaluate the effect of Coflex interspinous stabilization and vertebral arch pedicle screw implant on the stability and motion of the lumbar spine.
  
  
  METHODS
  The range of motion (ROM) of 6 fresh adult human cadaver lumbar spine specimens (L(1) approximately S(1)) was biomechanically tested in forward flexion/extension stretch, left/right lateral bending and left/right axial rotation. The ROM and neutral zone (NZ) of the segments L(2/3), L(3/4), and L(4/5) were measured and compared in 3 conditions, namely intact condition (a), rigid fixation of the segment L(4/5) with vertebral arch pedicle screw (b), and condition b plus L(3/4) stabilization with Coflex device (c).
  
  
  RESULTS
  The ROM of segment L(4/5) was significantly smaller in conditions b and c than in condition a in all the directions (P<0.05). The ROM of segment L(3/4) was significantly smaller in conditions a and c than in condition b in extension stretch (P<0.01), smaller in condition a than in conditions b and c in left/right lateral bending (P<0.01), and decreased significantly in the order of a<c<b in forward flexion stretch and left/right axial rotation (P<0.05). The ROM of segment L(2/3) was significantly smaller in conditions a and b than in condition c in extension stretch (P<0.01), but showed no significant differences between the 3 conditions in the other directions (P>0.05).
  
  
  CONCLUSIONS
  The ROM of the segment superior to the lumbar spine with rigid fixation increases in all the directions, but can be reduced with Coflex device implanted in the superior segment, which results in only increased ROM of the segment superior to Coflex device in extension stretch.
authors.affiliation: Department of Orthopedics and Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. zhongxuan1215@163.com
authors.forename: Zhong-xuan
authors.initials: ZX
authors.lastname: Mao
authors.forename: Jian-ming
authors.initials: JM
authors.lastname: Jiang
authors.forename: Hui-bo
authors.initials: HB
authors.lastname: Yan
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Zhao
authors.forename: Feng-long
authors.initials: FL
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Wu
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002102:Cadaver; D006801:Humans; D016268:Internal Fixators; D008159:Lumbar Vertebrae / Q000601:surgery*; D008875:Middle Aged; D009984:Orthopedic Fixation Devices; D016059:Range of Motion, Articular; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods