Acute eosinophilic pneumonia secondary to daptomycin: a report of three cases.
We describe 3 cases of daptomycin-induced pulmonary toxic effects that are consistent with drug-induced acute eosinophilic pneumonia. Patients presented similarly with dyspnea, cough, hypoxia, and diffuse ground-glass opacities at chest computed tomography. Clinical suspicion for this adverse drug event and cessation of daptomycin until definitive diagnosis can be made is crucial.
Miller
Becky A
BA
Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA. becky.miller@duke.edu
Gray
Alice
A
Leblanc
Thomas W
TW
Sexton
Daniel J
DJ
Martin
Andrew R
AR
Slama
Thomas G
TG
D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D017576:Daptomycin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D013902:Radiography, Thoracic; D014054:Tomography
D000900:Anti-Bacterial Agents; D017576:Daptomycin