title: An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Califf
authors.forename: Yuliya
authors.initials: Y
authors.lastname: Lokhnygina
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Cannon
authors.forename: Michael E
authors.initials: ME
authors.lastname: Stepanavage
authors.forename: Carolyn H
authors.initials: CH
authors.lastname: McCabe
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Musliner
authors.forename: Richard C
authors.initials: RC
authors.lastname: Pasternak
authors.forename: Michael A
authors.initials: MA
authors.lastname: Blazing
authors.forename: Robert P
authors.initials: RP
authors.lastname: Giugliano
authors.forename: Robert A
authors.initials: RA
authors.lastname: Harrington
authors.forename: Eugene
authors.initials: E
authors.lastname: Braunwald
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000188:drug therapy*; D001384:Azetidines / Q000627:therapeutic use*; D008078:Cholesterol, LDL / Q000097:blood; D004338:Drug Combinations; D000069499:Ezetimibe, Simvastatin Drug Combination; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015233:Models, Statistical; D010349:Patient Compliance; D012107:Research Design; D019821:Simvastatin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D001384:Azetidines; D008078:Cholesterol, LDL; D004338:Drug Combinations; D000069499:Ezetimibe, Simvastatin Drug Combination; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019821:Simvastatin