title: Impaction grafting of the acetabulum with a mixture of frozen, ground irradiated bone graft and porous synthetic bone substitute (Apapore 60).
abstract: The clinical and radiological results of 50 consecutive acetabular reconstructions in 48 patients using impaction grafting have been retrospectively reviewed. A 1:1 mixture of frozen, ground irradiated bone graft and Apapore 60, a synthetic bone graft substitute, was used in all cases. There were 13 complex primary and 37 revision procedures with a mean follow-up of five years (3.4 to 7.6). The clinical survival rate was 100%, with improvements in the mean Harris Hip Scores for pain and function. Radiologically, 30 acetabular grafts showed evidence of incorporation, ten had radiolucent lines and two acetabular components migrated initially before stabilising. Acetabular reconstruction in both primary and revision surgery using a 1:1 mixture of frozen, ground, irriadiated bone and Apapore 60 appears to be a reliable method of managing acetabular defects. Longer follow-up will be required to establish whether this technique is as effective as using fresh-frozen allograft.
authors.affiliation: Department of Orthopaedics, West Suffolk Hospital, Bury St Edmunds, UK. imcnamara@doctors.org.uk
authors.forename: I
authors.initials: I
authors.lastname: McNamara
authors.forename: S
authors.initials: S
authors.lastname: Deshpande
authors.forename: M
authors.initials: M
authors.lastname: Porteous
mesh_terms: D000077:Acetabulum / Q000000981:diagnostic imaging / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D001861:Bone Regeneration / Q000528:radiation effects; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000000981:diagnostic imaging / Q000379:methods*; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016062:Porosity; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation / Q000379:methods; D013242:Sterilization / Q000379:methods; D016019:Survival Analysis; D014021:Tissue Preservation / Q000379:methods; D016896:Treatment Outcome
chemical_list: D018786:Bone Substitutes; D017886:Durapatite