[Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia].
A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the majority of the described cultures, the content of cyclosporin B was much higher (about 40%) and the content of cyclosporin C was relatively low (about 3%). An appreciable content of cyclosporin (Leu4)Cs (3%) proved to be of interest.
Bibikova
M V
MV
Darkhanova
T A
TA
Spiridonova
I A
IA
Danilenko
A N
AN
Katlinskiĭ
A V
AV
D003524:Cyclosporins / Q000302:isolation & purification*; D006999:Hypocreales / Q000737:chemistry*; D007166:Immunosuppressive Agents / Q000302:isolation & purification*; D012800:Siberia; D012988:Soil Microbiology
D003524:Cyclosporins; D007166:Immunosuppressive Agents