Case report of congenital cystic adenomatoid malformation type III with lethal outcome.
We present a rare case of congenital cystic adenomatoid malformation (CCAM) type III (mycrocystic) in young, 19 years old primigravida. Diagnosis has been accomplished by ultrasound examination in 26th week of gestation. Hyperechogenic, mycrocystic mass was found in left pulmonary lobe with contra lateral displacement of mediastinum, hypoplasia of the right lung and extensive polyhydramnios. Prenatal therapy was based upon a serial of amniodrainage procedures and pharmacological inhibition of amniotic fluid production and uterine activity. Spontaneous preterm labor occurred at 34 weeks of gestation, Diagnosis was confirmed postnatal. Infant was ventilated due to respiratory insufficiency and was operated at the age of 24 hours. Lethal outcome occurred during the second day due to heavy respiratory insufficiency provoked by pulmonary hypoplasia. We discuss about types of a disease, prenatal diagnostic and therapeutic possibilities and pregnancy outcome.
Kulas
Tomislav
T
Clinic for Female Illness and Delivery, Clinical Hospital "Merkur", Zagreb, Croatia.
Duic
Zeljko
Z
Kostic
Zlatka Reljica
ZR
Zegarac
Zana
Z
Grizelj
Ruza
R
Habek
Dubravko
D
Hrgovic
Zlatko
Z
Marton
Ingrid
I
Izetbegovic
Sebija
S
D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000175:diagnosis / Q000628:therapy*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy*; D055815:Young Adult