title: The effect of smoking on gingival crevicular fluid levels of myeloperoxidase.
abstract: OBJECTIVE
  To compare the gingival crevicular fluid (GCF) myeloperoxidase (GM) levels in smokers and non-smokers.
  
  
  METHODS
  This study comprised 45 subjects: (a) 12 smokers with periodontitis, (b) 10 non-smokers with periodontitis, (c) 11 smokers with healthy periodontium, and (d) 12 non-smokers with healthy periodontium were recruited for the study and their GM levels were analyzed.
  
  
  CONCLUSIONS
  GM levels were significantly higher in smokers with periodontitis compared with others. Hence, more incidence of mutagenesis and cytotoxicity were noted at sites of inflammation mediated by GM in smokers compared with non-smokers.
authors.affiliation: Medical Imaging and Forensic Odontology Section, School of Dentistry, Rohtak, Haryana, India.
authors.forename: Balwant
authors.initials: B
authors.lastname: Rai
authors.forename: Jasdeep
authors.initials: J
authors.lastname: Kaur
authors.forename: S C
authors.initials: SC
authors.lastname: Anand
authors.forename: Kuldeep
authors.initials: K
authors.lastname: Laller
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D016022:Case-Control Studies; D055113:Chronic Periodontitis / Q000201:enzymology*; D005883:Gingival Crevicular Fluid / Q000201:enzymology*; D006801:Humans; D016296:Mutagenesis; D009195:Peroxidase / Q000032:analysis*; D012907:Smoking / Q000378:metabolism*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D009195:Peroxidase