Refractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: a case report.
We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis.
Fujita
Takayoshi
T
Department of Gastroenterology, Aichi Cancer Center Aichi Hospital, Okazaki City, Aichi 444-0011, Japan.
Ando
Takafumi
T
Sakakibara
Masatoshi
M
Hosoda
Waki
W
Goto
Hidemi
H
D000368:Aged; D005756:Gastritis / Q000150:complications / Q000188:drug therapy; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism*; D008297:Male; D010950:Plasma Cells / Q000276:immunology* / Q000473:pathology; D012598:Sclerosis; D013276:Stomach Ulcer / Q000209:etiology / Q000276:immunology* / Q000473:pathology
D007074:Immunoglobulin G