Evaluation of the analytical performance of the Nova StatSensor creatinine meter and reagent strip technology for whole blood testing.
OBJECTIVE
To evaluate the analytical performance of the Nova StatSensor creatinine meter.


METHODS
Imprecision, linearity, patient correlation and interference studies were completed.


RESULTS
Total imprecision was 4.5-9.1%CV and a linear measurement range of 93-863 micromol/L (1.05-9.76 mg/dL) was verified. Whole blood creatinine results correlated well with laboratory plasma measurements (R(2)=0.9328) but exhibited a negative proportional bias. In vitro, high levels of creatine and urea falsely elevated creatinine measurement.


CONCLUSIONS
The creatinine meter provides reliable measurement across a clinically relevant range and has potential use in point-of-care testing.
Schnabl
Kareena L
KL
Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S1A8, Canada.
Bagherpoor
Sousan
S
Diker
Pauline
P
Cursio
Christine
C
Dubois
Jeffrey
J
Yip
Paul M
PM
D003404:Creatinine / Q000097:blood*; D006801:Humans; D019095:Point-of-Care Systems; D011934:Reagent Strips; D015203:Reproducibility of Results
D011934:Reagent Strips; D003404:Creatinine