title: Structural and DNA cleavage of sugar-derived Schiff base ligands and their dinuclear Cu(II) complexes.
abstract: Neutral dinuclear Cu(II) complexes of Schiff base ligands derived from D-glucose have been synthesized and structurally characterized. These complexes were evaluated for their interaction with DNA, and DNA cleavage was observed even in the presence of radical inhibitors.
authors.affiliation: Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India.
authors.forename: Subbiah
authors.initials: S
authors.lastname: Nagarajan
authors.forename: Anupa
authors.initials: A
authors.lastname: Kumbhar
authors.forename: Babu
authors.initials: B
authors.lastname: Varghese
authors.forename: Thangamuthu Mohan
authors.initials: TM
authors.lastname: Das
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004247:DNA / Q000378:metabolism*; D006031:Glycosylation; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D012545:Schiff Bases / Q000737:chemistry*
chemical_list: D002241:Carbohydrates; D008024:Ligands; D009942:Organometallic Compounds; D012545:Schiff Bases; D003300:Copper; D004247:DNA