[Gamma-rhythm, positive, negative symptoms and cognitive dysfunction in schizophrenia].
We studied characteristics of gamma-band (30-40 Hz) EEG in dependence on the prevalence of positive or negative symptoms of schizophrenia, taking into account the state of cognitive functions. Twenty patients with ICD-10 diagnosis of schizophrenia, with different disease duration (first episode and duration of more than two years) and 38 healthy people were studied. The presence and intensity of positive and negative symptoms were measured by the PANSS scale and cognitive functions were assessed using neuropsychological tests. Compared to the controls, the gamma-rhythm power was higher in patients with the prevalence of positive symptoms and lower in patients with negative symptoms. The reduced number of coherent relations, in particular, interhemispheric ones, and the absence of gamma-band synchronization in different brain areas were found in patients as well.
Magomedov
R A
RA
Garakh
Zh V
ZhV
Orekhov
Iu V
IuV
Zaĭtseva
Iu S
IuS
Strelets
V B
VB
D000328:Adult; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D018450:Disease Progression; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D015995:Prevalence; D012559:Schizophrenia / Q000150:complications* / Q000503:physiopathology; D012720:Severity of Illness Index