title: Higher body mass index is not associated with worse pain outcomes after primary or revision total knee arthroplasty.
abstract: We assessed whether higher body mass index (BMI) is associated with higher risk of moderate-severe knee pain 2 and 5 years after primary or revision total knee arthroplasty (TKA).We adjusted for sex, age, comorbidity, operative diagnosis, and implant fixation in multivariable logistic regression. Body mass index (reference, b 25 kg/m2) was not associated with moderate severe knee pain at 2 years post primary TKA (odds ratio [95% confidence interval], 25-29.9, 1.02[0.75-1.39], P = .90; 30-34.9, 0.93 [0.65-1.34], P = .71; 35-39.9, 1.16 [0.77-1.74], P = .47; ≥ 40,1.09 [0.69-1.73], [all P values ≥ .47]). Similarly, BMI was not associated with moderate-severe pain at 5-year primary TKA and at 2-year and 5-year revision TKA follow-up. Lack of association of higher BMI with poor pain outcomes post-TKA implies that TKA should not be denied to obese patients for fear of suboptimal outcomes.
authors.affiliation: Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, MN, USA.
authors.forename: Jasvinder A
authors.initials: JA
authors.lastname: Singh
authors.forename: Sherine E
authors.initials: SE
authors.lastname: Gabriel
authors.forename: David G
authors.initials: DG
authors.lastname: Lewallen
mesh_terms: D000367:Age Factors; D000368:Aged; D018771:Arthralgia / Q000209:etiology* / Q000503:physiopathology*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D015992:Body Mass Index; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D012086:Reoperation / Q000009:adverse effects; D012720:Severity of Illness Index; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome