title: Juvenile paracoccidioidomycosis in urban area: report of two cases.
abstract: We present two cases of juvenile form of paracoccidioidomycosis (PCM), a systemic mycosis frequently found in rural areas, whose prognosis is poor in children and young adults. They are a 14-year-old boy and a 25-year-old woman, both residents in an urban area in São Paulo - Brazil, without any history of travelling to an endemic area. They have been admitted to the hospital due to fever, weight loss and lymphadenopathy. The diagnosis was confirmed by serologic and histopathologic study. Patients have recovered after therapy with oral itraconazole and were discharged from hospital, maintaining outpatient visits. In this article, the authors discuss the unusual presentation of PCM in an urban area.
authors.affiliation: Infectious Diseases Department, Hospital do Servidor Público Estadual Rua Pedro de Toledo, n. 1800 CEP 04039-004, São Paulo, SP, Brazil. rodrigoccarneiro@gmail.com
authors.forename: Rodrigo da Costa
authors.initials: Rda C
authors.lastname: Carneiro
authors.forename: Bianca Grassi de
authors.initials: BG
authors.lastname: Miranda
authors.forename: Carlos
authors.initials: C
authors.lastname: Camilo Neto
authors.forename: Marina K
authors.initials: MK
authors.lastname: Tsukumo
authors.forename: Cibele Lc
authors.initials: CL
authors.lastname: Fonseca
authors.forename: João Silva de
authors.initials: JS
authors.lastname: Mendonça
mesh_terms: D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000188:drug therapy; D014505:Urban Population
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole