Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao.
Four fluoroquinolone antibiotics (norfloxacin, ciprofloxacin, lomefloxacin, and enrofloxacin) in tap water in Guangzhou and Macao were analyzed using high performance liquid chromatography fluorescence detection. The results showed that all target antibiotics were detected in high rate both in Guangzhou (77.5%) and Macao (100%), ranging from 1.0 to 679.7 ng/L (SD <or= 37.6) in Guangzhou, and from 2.0 to 37.0 ng/L (SD <or= 2.5) in Macao. The fluoroquinolone antibiotics pollution in tap water widely distributes in Guangzhou and Macao. In addition, the effect of rainfall on concentration of fluoroquinolone antibiotics in south China was also investigated. Our result indicates that the antibiotic concentration in tap water in Guangzhou tends to obviously reduce at the beginning of rainy season, even decreases below the limit of quantification immediately. Thus, it was clarified that the heavy rain in south China has the function of reducing the fluoroquinolone antibiotics concentrations in tap water.
Yiruhan
Department of Environmental Engineering, Jinan University, Huangpudadaoxi 601, Guangzhou 510632, China.
Wang
Qiao-Jun
QJ
Mo
Ce-Hui
CH
Li
Yan-Wen
YW
Gao
Peng
P
Tai
Yi-Ping
YP
Zhang
Yan
Y
Ruan
Zhi-Li
ZL
Xu
Jia-Wei
JW
D000900:Anti-Bacterial Agents / Q000032:analysis*; D002681:China; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin / Q000032:analysis; D000077422:Enrofloxacin; D024841:Fluoroquinolones / Q000032:analysis*; D009643:Norfloxacin / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D014874:Water Pollutants, Chemical; D000077422:Enrofloxacin; D002939:Ciprofloxacin; C053091:lomefloxacin; D009643:Norfloxacin