title: The role of polyphenols in cardiovascular disease.
abstract: Epidemiological studies suggest that diets rich in polyphenols may be associated with reduced incidence of cardiovascular disorders (mainly coronary heart disease and myocardial infarction). However, the mechanisms explaining this correlation have not been fully elucidated. Current evidence suggests that polyphenols, acting at the molecular level, improve endothelial function and inhibit platelet aggregation. In view of their antithrombotic, anti-inflammatory, and anti-aggregative properties, these compounds may play a roles in the prevention and treatment of cardiovascular disease.
authors.affiliation: Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Michalska
authors.forename: Anna
authors.initials: A
authors.lastname: Gluba
authors.forename: Dimitri P
authors.initials: DP
authors.lastname: Mikhailidis
authors.forename: Piotr
authors.initials: P
authors.lastname: Nowak
authors.forename: Agata
authors.initials: A
authors.lastname: Bielecka-Dabrowa
authors.forename: Jacek
authors.initials: J
authors.lastname: Rysz
authors.forename: Maciej
authors.initials: M
authors.lastname: Banach
mesh_terms: D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000517:prevention & control*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology; D005419:Flavonoids / Q000494:pharmacology*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D010636:Phenols / Q000494:pharmacology*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D059808:Polyphenols
chemical_list: D005419:Flavonoids; D010636:Phenols; D010975:Platelet Aggregation Inhibitors; D059808:Polyphenols