Severe duodenal hemorrhage induced by Lugol's solution administered for thyroid crisis treatment.
Lugol's solution is an iodinated agent used for treating thyroid crisis. It is primarily used in diagnostic tests for esophageal diseases. However, Lugol's solution can cause local mucosal injury and hemorrhage. We report, for the first time, a case of 34-year-old man who exhibited severe duodenal hemorrhage induced by Lugol's solution that was used to treat thyroid crisis. The quantity of Lugol's solution used for treating thyroid crisis is much higher than that used for mucosal disease investigation. Clinical practitioners should be aware of gastrointestinal hemorrhage when using Lugol's solution for the treatment of thyroid crisis.
Kinoshita
Hiroyuki
H
Department of Internal Medicine, Tokyo Metropolitan Bokutoh Hospital. hkinoshita-tky@umin.ac.jp
Yasuda
Mutsuko
M
Furumoto
Youhei
Y
Watanabe
Naoko
N
Horiuchi
Takao
T
Murayama
Minekazu
M
Kitamura
Mari
M
Kaneko
Shingo
S
Inoshita
Seiji
S
Maruyama
Yasuki
Y
Suenaga
Matsuhiko
M
Fujita
Hiroshi
H
Fujiki
Kazuhiko
K
Yakushiji
Fumiatsu
F
D000328:Adult; D004378:Duodenal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007454:Iodides / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D013958:Thyroid Crisis / Q000175:diagnosis / Q000188:drug therapy*
D007454:Iodides; C010389:Lugol's solution