Water-soluble constituents from the bark of Elaeagnus pungens and their cytotoxic activities.
Three new water-soluble compounds, pungens A-C, along with four known compounds including two phenol glycosides, one secoiso-flavanol and one phenol ether, have been isolated from the bark of Elaeagnus pungens. Among them, pungen C (7) (200 microg/ml) was tested in SGC-7901 and BEL-7404 tumor cell lines, and showed moderate cytotoxic activity. The structures of the new compounds were elucidated on the basis of spectroscopic data and chemical evidence.
Wu
Yan-Bing
YB
Henan Institute of Science and Technology, Xinxiang, Henan, China.
Gu
Yong
Y
Ouyang
Ming-An
MA
D000840:Anisoles / Q000737:chemistry / Q000302:isolation & purification*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D031263:Elaeagnaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification; D024301:Plant Bark / Q000737:chemistry; D052999:Quinazolinones / Q000737:chemistry / Q000302:isolation & purification; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*
D000840:Anisoles; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010636:Phenols; D052999:Quinazolinones; D012503:Saponins; C549369:pungen A; C549368:pungen B; C549370:pungen C; D005707:Gallic Acid; C014013:glycosine