title: [Recent progress on diagnosis and treatment of benign symmetric lipomatosis].
abstract: OBJECTIVE
  To introduce recent progress on diagnosis and treatment of benign symmetric lipomatosis (BSL).
  
  
  METHODS
  Detailed clinical data of 6 patients with BSL were reviewed and analyzed. We present a summary of the clinical symptoms, physical sign, diagnosis and therapeutic methods of BSL. And related literatures were discussed together.
  
  
  RESULTS
  All of 6 patients have excessive subcutaneous fat deposit predominantly around neck. One patients had upper extremity localizations. Six patients had the complication of left ventricular diastolic function changes, glucose intolerance or diabetes mellitus, chronic hepatopathy, hyperuricemia and sleep apnea syndrome in one or more. One patients with several symptoms occur simultaneously, another one female patient was accompanied by all symptoms but chronic hepatopathy. Five male patient were alcohol abusers. Total neck lipectomy and abstinence from alcohol were performed on 5 patients. One patient refused treatment. During a follow-up of 3 months to 4 years, one patients was relapsed again, and no recurrence was seen in another 4 patients. All patho logical results were nonencapsulated fat.
  
  
  CONCLUSIONS
  BSL is a lipodystrophy caused by diffuse fatty tissue, symmetry deposition in the neck and shoulder subcutaneous fascia space or deep fascial space. The highest incidence favors to middle-aged man who is alcoholic. Chronic alcohol addiction and typical clinical symptoms help to diagnosis BSL. Lipectomy represents a successful procedure in treating BSL.
authors.affiliation: Department of Otolaryngology Head and Neck, China-Japan Union Hospital of Jilin University, Changchun, China.
authors.forename: Yingnan
authors.initials: Y
authors.lastname: Kan
authors.forename: Ping
authors.initials: P
authors.lastname: Yao
authors.forename: Weihong
authors.initials: W
authors.lastname: Xin
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Yue
authors.forename: Jiajing
authors.initials: J
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D005205:Fascia / Q000473:pathology; D005260:Female; D006801:Humans; D015187:Lipectomy; D008069:Lipomatosis, Multiple Symmetrical / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D012782:Shoulder / Q000473:pathology