title: Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.
abstract: A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
authors.forename: Li
authors.initials: L
authors.lastname: Cui
authors.forename: Longwu
authors.initials: L
authors.lastname: Ye
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang
mesh_terms: D001381:Azepines / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001381:Azepines; D050607:Organogold Compounds