The significance of relative conductivity on thin layers in EEG sensitivity distributions.
Volume conductor head models contain thin tissue layers, some of which have highly contrasting conductivity values relative to neighboring tissues. We expound the cerebrospinal fluid (CSF) and the six cortical layers of the gray matter. The dual nature of the CSF competes with the well-known shunting behavior of the skull. The incorporation of the six ultra thin cortical layers demonstrate the significance of the electrical attraction and shunting of lead field currents in multilayered tissues owing to the inherent conductive properties of each tissue. We relate the similar effects of the CSF to the diploë, i.e., the soft bone between the two hard bone layers of the skull. A natural subsequence of this article will allow researchers and clinicians to conceptually understand the measurement sensitivity distribution of a bipolar electroencephalography (EEG) lead. We recommend including the highly conductive thin layers such as the diploë of the skull and the CSF into head models as well as further investigation into the cortical layers I-VI of the gray matter. Comprehensively, when a thin tissue layer differs in relative conductivity from its neighboring layers, it should be included in the model owing to its influence upon the EEG lead fields, i.e., the measurement sensitivity distributions.
Wendel
Katrina
K
Department of Biomedical Engineering, Tampere University of Technology, Korkeakoulunkatu 3, Tampere, Finland. katrina.wendel@tut.fi
Väisänen
Juho
J
Kybartaite
Asta
A
Hyttinen
Jari
J
Malmivuo
Jaakko
J
D000465:Algorithms; D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D003198:Computer Simulation; D004553:Electric Conductivity; D004569:Electroencephalography / Q000379:methods*; D004574:Electromagnetic Fields; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity