title: Psychometric properties of the Perform Questionnaire: a brief scale for assessing patient perceptions of fatigue in cancer.
abstract: OBJECTIVE
  Fatigue is a symptom with a relevant impact on the daily lives of cancer patients and is gaining importance as an outcome measure. The Perform Questionnaire (PQ) is a new scale originally developed among Spanish-speaking patients for the assessment of perception and beliefs about fatigue in cancer patients.
  
  
  METHODS
  An observational longitudinal multicenter study was carried out on cancer patients with fatigue. Fatigue-specific measures (FACT-F), generic health-related quality-of-life measures (NHP), and PQ were gathered at baseline and 3 months later. Feasibility, reliability (internal consistency and test-retest), validity, sensitivity to change, and minimally important differences were analysed.
  
  
  RESULTS
  Four hundred thirty-seven patients were included in the study: 60.5% were women, the mean age was 59.1 years, the mean time from diagnosis was 2.2 years, 33.6% of patients had breast cancer, and 29.1% had anaemia (haemoglobin (Hb) <11 g/dL). Low levels of missing items and ceiling/floor effects (<10%) were found. The overall Cronbach's alpha and intraclass correlation coefficient were 0.94 and 0.83, respectively. The PQ score was associated with fatigue intensity, the need for a caregiver, and the Hb level. Its association was stronger with the FACT-F than with non-specific health measures (NHP). The PQ showed good sensitivity to change for improved and worsening health status. A minimally important difference of 3.5 was estimated in patients whose Hb level had improved by at least 1 g/dL.
  
  
  CONCLUSIONS
  The PQ measured the attitudes and beliefs about fatigue among cancer patients in clinical practice and showed good psychometric properties among Spanish-speaking patients.
authors.affiliation: 3D Health Research, Barcelona, Spain. ebaro@3dhealth.es
authors.forename: Eva
authors.initials: E
authors.lastname: Baró
authors.forename: Joan
authors.initials: J
authors.lastname: Carulla
authors.forename: Javier
authors.initials: J
authors.lastname: Cassinello
authors.forename: Ramón
authors.initials: R
authors.lastname: Colomer
authors.forename: Jesús García
authors.initials: JG
authors.lastname: Mata
authors.forename: Pere
authors.initials: P
authors.lastname: Gascón
authors.forename: Jose Antonio
authors.initials: JA
authors.lastname: Gasquet
authors.forename: Cesar A
authors.initials: CA
authors.lastname: Rodríguez
authors.forename: Vicente
authors.initials: V
authors.lastname: Valentín
mesh_terms: D000368:Aged; D000740:Anemia / Q000150:complications / Q000209:etiology; D001294:Attitude to Health; D005221:Fatigue / Q000209:etiology / Q000523:psychology*; D005240:Feasibility Studies; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D011446:Prospective Studies; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D013030:Spain; D011795:Surveys and Questionnaires
chemical_list: D006454:Hemoglobins