A comparative study of cutaneous manifestations of hyperandrogenism in obese and non-obese Taiwanese women.
OBJECTIVE
The aim of the study was to investigate the impact of obesity on cutaneous manifestations of clinical hyperandrogenism.


METHODS
A total of 627 Taiwanese women of reproductive age were included.


RESULTS
Women with acne had a greater incidence of PCOS, hyperandrogenemia and hirsutism, and had higher serum total testosterone than women without acne. Obese women, even with significantly higher serum total testosterone levels, had lower incidence of acne than non-obese women, and this was found uniformly across the hyperandrogenemia and the non-hyperandrogenemia groups. Although BMI had a significantly positive correlation with serum total testosterone in the studied women, obese women presented less acne than the non-obese subjects.


CONCLUSIONS
Obese women, regardless of having higher serum testosterone levels, had a lower incidence of acne than non-obese women; however, the factuality was not found in hirsutism.
Yang
Jen-Hung
JH
Department of Dermatology, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, 110 Sec. 1 Jianguo N. Road, Taichung, Taiwan.
Weng
Shun-Long
SL
Lee
Ching-Yin
CY
Chou
Szu-Yuan
SY
Hsu
Chun-Sen
CS
Hsu
Ming-I
MI
D000152:Acne Vulgaris / Q000097:blood / Q000150:complications* / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D005260:Female; D006628:Hirsutism / Q000097:blood / Q000150:complications / Q000453:epidemiology; D006801:Humans; D017588:Hyperandrogenism / Q000097:blood* / Q000150:complications*; D015994:Incidence; D009765:Obesity / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000150:complications / Q000453:epidemiology; D013624:Taiwan / Q000453:epidemiology; D013739:Testosterone / Q000097:blood*; D055815:Young Adult
D013739:Testosterone