title: A new sulfated alpha-ionone glycoside from Sonchus erzincanicus Matthews.
abstract: Sonchus erzincanicus (Asteraceae) is an endemic species in Turkey, where six Sonchus species grow. In this study, a phytochemical study was performed on the aerial parts of the plant. The study describes the isolation and structure elucidation of five flavonoids and two a-ionone glycosides from S. erzincanicus. The compounds were isolated using several and repeated chromatographic techniques from ethyl acetate and aqueous phases that were partitioned from a methanol extract obtained from the plant. 5,7,3',4'-Tetrahydroxy-3-methoxyflavone (1) and quercetin 3-O-beta-D-glucoside (2) were isolated from the ethyl acetate phase, while corchoionoside C 6'-O-sulfate (3), corchoionoside C (4), luteolin 7-O-glucuronide (5) and luteolin 7-O-beta-D-glucoside (6), apigenin 7-O-glucuronide (7) were isolated from the aqueous phase. Corchoionoside C 6'-O-sulfate (3), isolated for the first time from a natural source, was a new compound. The structures of the compounds were elucidated by means of 1H-NMR, 13C-NMR, 2D-NMR (COSY, HMQC, HMBC) and ESI-MS.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey. uozgen@atauni.edu.tr
authors.forename: Ufuk
authors.initials: U
authors.lastname: Ozgen
authors.forename: Handan
authors.initials: H
authors.lastname: Sevindik
authors.forename: Cavit
authors.initials: C
authors.lastname: Kazaz
authors.forename: Demet
authors.initials: D
authors.lastname: Yigit
authors.forename: Ali
authors.initials: A
authors.lastname: Kandemir
authors.forename: Hasan
authors.initials: H
authors.lastname: Secen
authors.forename: Ihsan
authors.initials: I
authors.lastname: Calis
mesh_terms: D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D045792:Norisoprenoids / Q000737:chemistry* / Q000302:isolation & purification; D031184:Sonchus / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013463:Sulfuric Acid Esters / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D005419:Flavonoids; D005960:Glucosides; D045792:Norisoprenoids; D013463:Sulfuric Acid Esters; C105665:corchoionoside C; C551084:corchoionoside C 6-O-sulfate; C011879:alpha-ionone