title: Candidate gene markers involved in San Daniele ham quality.
abstract: San Daniele dry-cured hams (also known as prosciutto) are produced in the Northeastern region of Italy. This high value product requires high quality fresh meat to avoid processing problems. The Sterol Regulatory Element Binding Protein-1 (SREBF1) is a transcription factor involved in the regulation of fatty acid synthesis in muscle and adipose tissues. The SREBF1 gene, its regulating genes SCAP and MBTPS1, and one of its target genes, SCD, were investigated for associations with several meat quality traits of San Daniele hams. Significant associations of some gene markers were found with carcass weight, lean percentage, backfat thickness, ham green weight, ham fat cover thickness, shear force (WBSF), salting losses and instrumental colour of both lean and fat. These findings provide initial evidences that SNPs in SREBF1, SCAP, MBTPS1 and SCD are associated with San Daniele ham quality and may be considered as markers for selective breeding programs.
authors.affiliation: Veterinary Physiology and Nutrition Lab, Department of Food Science, University of Udine, Via Sondrio 2A, 33100 Udine, Italy. benedicte.renaville@uniud.it
authors.forename: B
authors.initials: B
authors.lastname: Renaville
authors.forename: E
authors.initials: E
authors.lastname: Piasentier
authors.forename: B
authors.initials: B
authors.lastname: Fan
authors.forename: M
authors.initials: M
authors.lastname: Vitale
authors.forename: A
authors.initials: A
authors.lastname: Prandi
authors.forename: M F
authors.initials: MF
authors.lastname: Rothschild
mesh_terms: D000818:Animals; D003116:Color; D004041:Dietary Fats; D005524:Food Technology; D005819:Genetic Markers; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism; D008460:Meat / Q000592:standards*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D009124:Muscle Proteins / Q000235:genetics*; D018482:Muscle, Skeletal / Q000378:metabolism*; D009929:Organ Size; D020641:Polymorphism, Single Nucleotide; D043484:Proprotein Convertases / Q000235:genetics / Q000378:metabolism; D012697:Serine Endopeptidases / Q000235:genetics / Q000378:metabolism; D013230:Stearoyl-CoA Desaturase / Q000235:genetics / Q000378:metabolism; D051780:Sterol Regulatory Element Binding Protein 1 / Q000235:genetics / Q000378:metabolism; D013314:Stress, Mechanical; D013552:Swine / Q000235:genetics
chemical_list: D004041:Dietary Fats; D005819:Genetic Markers; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; D009124:Muscle Proteins; C102196:SREBP cleavage-activating protein; D051780:Sterol Regulatory Element Binding Protein 1; D013230:Stearoyl-CoA Desaturase; D043484:Proprotein Convertases; D012697:Serine Endopeptidases; C115575:membrane-bound transcription factor peptidase, site 1