title: A hybrid 1D and 3D approach to hemodynamics modelling for a patient-specific cerebral vasculature and aneurysm.
abstract: In this paper we present a hybrid 1D/3D approach to haemodynamics modelling in a patient-specific cerebral vasculature and aneurysm. The geometric model is constructed from a 3D CTA image. A reduced form of the governing equations for blood flow is coupled with an empirical wall equation and applied to the arterial tree. The equation system is solved using a MacCormack finite difference scheme and the results are used as the boundary conditions for a 3D flow solver. The computed wall shear stress (WSS) agrees with published data.
authors.affiliation: Bioengineering Institute, University of Auckland, New Zealand. harvey.ho@auckland.ac.nz
authors.forename: Harvey
authors.initials: H
authors.lastname: Ho
authors.forename: Gregory
authors.initials: G
authors.lastname: Sands
authors.forename: Holger
authors.initials: H
authors.lastname: Schmid
authors.forename: Kumar
authors.initials: K
authors.lastname: Mithraratne
authors.forename: Gordon
authors.initials: G
authors.lastname: Mallinson
authors.forename: Peter
authors.initials: P
authors.lastname: Hunter
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure; D002533:Cerebral Angiography / Q000379:methods*; D002536:Cerebral Arteries / Q000503:physiopathology*; D003198:Computer Simulation; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008955:Models, Cardiovascular; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods*