title: Novel bisabolane sesquiterpenes from the marine-derived fungus Verticillium tenerum.
abstract: Chemical investigations of the marine-derived fungus Verticillium tenerum yielded two new hydroxylated bisabolane-type sesquiterpenes verticinol A (1) and B (2). The planar structures of the new compounds were elucidated by employing spectroscopic (NMR, UV, and IR) and mass spectrometric techniques. The absolute configuration of the cyclohexenyl moiety was deduced by a combination of CD spectroscopy and NOESY measurements.
authors.affiliation: Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.
authors.forename: Celso
authors.initials: C
authors.lastname: Almeida
authors.forename: Somaia
authors.initials: S
authors.lastname: Elsaedi
authors.forename: Stefan
authors.initials: S
authors.lastname: Kehraus
authors.forename: Gabriele M
authors.initials: GM
authors.lastname: König
mesh_terms: D002942:Circular Dichroism; D056890:Eukaryota / Q000382:microbiology*; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D020172:Verticillium / Q000737:chemistry*
chemical_list: D012717:Sesquiterpenes