Random lasing in bone tissue.
Owing to the low-loss and high refractive index variations derived from the basic building block of bone structure, we, for the first time to our knowledge, demonstrate coherent random lasing action originated from the bone structure infiltrated with laser dye, revealing that bone tissue is an ideal biological material for random lasing. Our numerical simulation shows that random lasers are extremely sensitive to subtle structural changes even at nanoscales and can potentially be an excellent tool for probing nanoscale structural alterations in real time as a novel spectroscopic modality.
Song
Qinghai
Q
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA.
Xiao
Shumin
S
Xu
Zhengbin
Z
Liu
Jingjing
J
Sun
Xuanhao
X
Drachev
Vladimir
V
Shalaev
Vladimir M
VM
Akkus
Ozan
O
Kim
Young L
YL
D000818:Animals; D001842:Bone and Bones / Q000528:radiation effects*; D002417:Cattle; D004396:Coloring Agents; D005240:Feasibility Studies; D007834:Lasers
D004396:Coloring Agents