title: Semen quality and aging: analysis of 9.168 samples in Cordoba. Argentina.
abstract: OBJECTIVE
  Concomitantly with the actual trend towards later fathering, more detailed studies are necessary to establish the relationship between male age and seminal features. The objective of the present paper was to evaluate the relationship of men age with semen quality and with the seminal levels of epididymal and accessory gland markers.
  
  
  METHODS
  The study was conducted as a retrospective study of 9168 cases obtained from the Andrology and Reproduction Laboratory in Cordoba, Argentina for 10 years (1995-2004) (men ages 20 to 77). An important number of factors such as abstinence time, toxic habits, work conditions and drugs consumption has been statistically considered. The parameters measured were: seminal volume, sperm concentration, total sperm count, sperm motility, morphology and viability. Seminal levels of alpha-glucosidase, fructose and citric acid were also evaluated.
  
  
  RESULTS
  We detected a significant decrease in seminal volume, sperm count, motility, viability and normal morphology, and a reduction in alpha-glucosidase and fructose levels in relation to age.
  
  
  CONCLUSIONS
  Since semen quality is a tool for fertility prognosis estimation, the weight of evidence indicates that men may become progressively less fertile as they get older. Couples who decide to delay childbearing should be warned about this matter.
authors.affiliation: Andrology and Reproduction Laboratory. Cordoba. Argentina.
authors.forename: Rosa Isabel
authors.initials: RI
authors.lastname: Molina
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Martini
authors.forename: Andrea
authors.initials: A
authors.lastname: Tissera
authors.forename: José
authors.initials: J
authors.lastname: Olmedo
authors.forename: Daniel
authors.initials: D
authors.lastname: Senestrari
authors.forename: Marta Fiol
authors.initials: MF
authors.lastname: de Cuneo
authors.forename: Rubén Daniel
authors.initials: RD
authors.lastname: Ruiz
mesh_terms: D000328:Adult; D000375:Aging; D001118:Argentina; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055101:Semen Analysis; D055815:Young Adult