Using graphene to protect DNA from cleavage during cellular delivery.
We have proved that functionalized nanoscale graphene oxide can protect oligonucleotides from enzymatic cleavage and efficiently deliver oligonucleotides into cells.
Lu
Chun-Hua
CH
The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, PR China.
Zhu
Chun-Ling
CL
Li
Juan
J
Liu
Jing-Jing
JJ
Chen
Xi
X
Yang
Huang-Hao
HH
D002244:Carbon / Q000737:chemistry* / Q000378:metabolism; D002470:Cell Survival; D006367:HeLa Cells; D006801:Humans; D009841:Oligonucleotides / Q000008:administration & dosage* / Q000737:chemistry / Q000378:metabolism
D009841:Oligonucleotides; D002244:Carbon