title: Evaluation of the analytical performance of the Nova StatSensor creatinine meter and reagent strip technology for whole blood testing.
abstract: OBJECTIVE
  To evaluate the analytical performance of the Nova StatSensor creatinine meter.
  
  
  METHODS
  Imprecision, linearity, patient correlation and interference studies were completed.
  
  
  RESULTS
  Total imprecision was 4.5-9.1%CV and a linear measurement range of 93-863 micromol/L (1.05-9.76 mg/dL) was verified. Whole blood creatinine results correlated well with laboratory plasma measurements (R(2)=0.9328) but exhibited a negative proportional bias. In vitro, high levels of creatine and urea falsely elevated creatinine measurement.
  
  
  CONCLUSIONS
  The creatinine meter provides reliable measurement across a clinically relevant range and has potential use in point-of-care testing.
authors.affiliation: Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S1A8, Canada.
authors.forename: Kareena L
authors.initials: KL
authors.lastname: Schnabl
authors.forename: Sousan
authors.initials: S
authors.lastname: Bagherpoor
authors.forename: Pauline
authors.initials: P
authors.lastname: Diker
authors.forename: Christine
authors.initials: C
authors.lastname: Cursio
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Dubois
authors.forename: Paul M
authors.initials: PM
authors.lastname: Yip
mesh_terms: D003404:Creatinine / Q000097:blood*; D006801:Humans; D019095:Point-of-Care Systems; D011934:Reagent Strips; D015203:Reproducibility of Results
chemical_list: D011934:Reagent Strips; D003404:Creatinine