[Studies on technology optimization for extracting triterpenoid saponins from Picria felterrae by multi-target grading method].
OBJECTIVE
To study the optimum extraction conditions of triterpenoid saponins from Picria felterrae.


METHODS
The optimum extraction conditions were investigated by the contents of the total glycosides and picfeltarraenine I A and I B, using orthogonal test.


RESULTS
The optimum extraction conditions were as follows: using 70% alcohol of 19 times than the amount of original material soaking 3 hours, extracting twice with hot reflux method at 80 degrees C, 3h the first time, 1 h the second time.


CONCLUSIONS
The selected extraction conditions are convenient and practical with high accuracy, and could be used as a reference for industrial production.
Fang
Hong
H
Guangxi Institute of Botany, Guangxi Zhuangzu Autonomous Region and Academia Sinica, Guilin 541006, China. GXZWSFH@yahoo.cn
Ning
De-sheng
DS
Liang
Xiao-yan
XY
D002851:Chromatography, High Pressure Liquid; D003124:Colorimetry / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D032266:Scrophularia / Q000737:chemistry*; D012997:Solvents; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors
D004365:Drugs, Chinese Herbal; D012503:Saponins; D012997:Solvents; D000431:Ethanol