Antibacterial nanoparticle monolayers prepared on chemically inert surfaces by cooperative electrostatic adsorption (CELA).
Cooperative electrostatic adsorption (CELA) is used to deposit monolayer coatings of silver nanoparticles on relatively chemically inert polymers, polypropylene, and Tygon. Medically relevant components (tubing, vials, syringes) coated by this method exhibit antibacterial properties over weeks to months with the coatings being stable under constant-flow conditions. Antibacterial properties of the coatings are due to a slow release of Ag(+) from the particles. The rate of this release is quantified by the dithiol-precipitation method coupled with inductively coupled plasma optical emission spectrometer (ICP-OES) analysis.
Huda
Sabil
S
Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, USA.
Smoukov
Stoyan K
SK
Nakanishi
Hideyuki
H
Kowalczyk
Bartlomiej
B
Bishop
Kyle
K
Grzybowski
Bartosz A
BA
D000327:Adsorption; D000890:Anti-Infective Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000378:metabolism; D006046:Gold / Q000737:chemistry; D008024:Ligands; D053768:Metal Nanoparticles / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D010100:Oxygen / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013053:Spectrophotometry / Q000379:methods; D055672:Static Electricity; D013499:Surface Properties
D000890:Anti-Infective Agents; D008024:Ligands; D012834:Silver; D006046:Gold; D010100:Oxygen