title: Pd-catalyzed cross-coupling reactions of amides and aryl mesylates.
abstract: A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: Karin
authors.initials: K
authors.lastname: Dooleweerdt
authors.forename: Brett P
authors.initials: BP
authors.lastname: Fors
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Buchwald
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; D008024:Ligands; D008698:Mesylates; D009942:Organometallic Compounds; D010165:Palladium