[Multiple ischemic strokes due to Borrelia garinii meningovasculitis].
The most frequent clinical manifestation of borreliosis in Switzerland is erythema migrans, with about 2500 patients each year. Neurological manifestations are rare, mostly hyperalgesic radiculitis (Bannwarth syndrome), aseptic meningitis or cranial nerve involvement. We report the first Swiss patient with meningovasculitis due to neuroborreliosis, with recurrent multiple ischemic strokes in multiple vascular territories. The treatment with ceftriaxone stopped the progression, but the patient is still suffering from severe invalidating cognitive disorders. We also comment on the pathophysiology and review the literature of other clinical cases.
Rey
V
V
Service de neurologie, département des neurosciences cliniques, centre hospitalier universitaire Vaudois, BH 13, 1011 Lausanne, Switzerland. vincianne.rey@chuv.ch
Du Pasquier
R
R
Muehl
A
A
Péter
O
O
Michel
P
P
D000890:Anti-Infective Agents / Q000627:therapeutic use; D015153:Blotting, Western; D015748:Borrelia burgdorferi Group; D002545:Brain Ischemia / Q000209:etiology* / Q000473:pathology; D002443:Ceftriaxone / Q000627:therapeutic use; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology; D006801:Humans; D020852:Lyme Neuroborreliosis / Q000150:complications* / Q000473:pathology / Q000523:psychology; D008279:Magnetic Resonance Imaging; D008297:Male; D008581:Meningitis / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D020521:Stroke / Q000209:etiology* / Q000473:pathology; D020293:Vasculitis, Central Nervous System / Q000209:etiology* / Q000473:pathology
D000890:Anti-Infective Agents; D002443:Ceftriaxone