Current management of wilms' tumor.
Wilms' tumor is the most common malignant renal tumor in children. Survival has improved dramatically over time as a result of prospective randomized clinical trials conducted by the pediatric cooperative cancer groups. Current research is directed toward identifying low-risk patients for whom a reduction in treatment intensity would decrease long-term morbidity. This article reviews the most recent advances in the biology and treatment of children with Wilms' tumor.
Nakamura
Leah
L
Department of Urology, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ, 85054, USA.
Ritchey
Michael
M
D002648:Child; D003937:Diagnosis, Differential; D005821:Genetic Techniques; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D010535:Laparoscopy / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008403:Mass Screening / Q000379:methods*; D009367:Neoplasm Staging; D009392:Nephrectomy / Q000379:methods*; D015995:Prevalence; D011379:Prognosis; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler; D006113:United Kingdom / Q000453:epidemiology; D009396:Wilms Tumor / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery