title: [Diversity in thalamic relay neurons: evidence for "bottom-up" and "top-down" information flow in thalamocortical pathways].
abstract: Thalamocortical (TC) pathways are still mainly understood as the gateway for ascending sensory-motor information into the cortex. However, it is now clear that a great many TC cells are involved in interactions between cortical areas via the thalamus. We review recent data, including our own, which demonstrate the generalized presence in rodent thalamus of two major TC cell types characterized, among other features, by their axon development, arborization and laminar targeting in the cortex. Such duality may allow inputs from thalamus to access cortical circuits via "bottom-up"-wired axon arbors or via "top-down"-wired axon arbors.
authors.forename: Francisco
authors.initials: F
authors.lastname: Clascá
authors.forename: Pablo
authors.initials: P
authors.lastname: Rubio-Garrido
authors.forename: María J
authors.initials: MJ
authors.lastname: Galazo
authors.forename: César
authors.initials: C
authors.lastname: Porrero
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology*; D009434:Neural Pathways; D009474:Neurons / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013788:Thalamus / Q000033:anatomy & histology / Q000502:physiology*