title: A new entry of amination reagents for heteroaromatic C-H bonds: copper-catalyzed direct amination of azoles with chloroamines at room temperature.
abstract: Chloroamine serves as an efficient amination reagent to the heteroaromatic C-H bond of azole under copper catalysis even at room temperature. This catalysis enables a rapid and concise construction of aminoazoles of great interest in biological and medicinal chemistry.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kawano
authors.forename: Koji
authors.initials: K
authors.lastname: Hirano
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Satoh
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
mesh_terms: D000586:Amination; D001393:Azoles / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D002700:Chloramines / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D013696:Temperature
chemical_list: D001393:Azoles; D002700:Chloramines; D007202:Indicators and Reagents; D002244:Carbon; D003300:Copper; D006859:Hydrogen; D009584:Nitrogen