Mass spectrometry: pneumococcal meningitis verified and Brucella species identified in less than half an hour.
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is currently being introduced for the rapid and accurate identification of bacteria. We describe 2 MALDI-TOF MS identification cases - 1 directly on spinal fluid and 1 on grown bacteria. Rapidly obtained results had great value for the continued treatment and for the elucidation of exposure.
Nyvang Hartmeyer
Gitte
G
Department of Bacteriology, Statens Serum Institut, Copenhagen, Denmark.
Kvistholm Jensen
Anne
A
Böcher
Sidsel
S
Damkjaer Bartels
Mette
M
Pedersen
Michael
M
Engell Clausen
Marianne
M
Abdul-Redha
Rawaa
R
Dargis
Rimtas
R
Schouenborg
Per
P
Højlyng
Niels
N
Kemp
Michael
M
Christensen
Jens Jørgen E
JJ
D015373:Bacterial Typing Techniques / Q000379:methods*; D002002:Brucella / Q000145:classification / Q000302:isolation & purification*; D002006:Brucellosis / Q000097:blood / Q000175:diagnosis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008586:Meningitis, Pneumococcal / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000382:microbiology*; D008875:Middle Aged; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*