[In vitro activity of Ingavirin against influenza virus A (H3N2)].
The comparative analysis of the efficacy of Ingavirin and etiotropic chemotherapeutics, such as Arbidol and Remantadin, against the influenza virus A (H3N2) performed with the use of susceptible permanent cell cultures showed that in the used concentrations Ingavirin was efficient in inhibition of the virus cytopathic activity, formation of the specific hemagglutinin and reproduction of the virus (by the accumulation).
Loginova
S Ia
SIa
Borisevich
S V
SV
Semenova
I V
IV
Maksimov
V A
VA
Bondarev
V P
VP
Nebol'sin
V E
VE
D000577:Amides / Q000494:pharmacology*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002208:Caproates; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D003998:Dicarboxylic Acids / Q000494:pharmacology*; D004285:Dogs; D006385:Hemagglutination Inhibition Tests; D007093:Imidazoles / Q000494:pharmacology*; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects* / Q000502:physiology; D013552:Swine; D014779:Virus Replication / Q000187:drug effects
D000577:Amides; D000998:Antiviral Agents; D002208:Caproates; D003998:Dicarboxylic Acids; D007093:Imidazoles; C539419:pentanedioic acid imidazolyl ethanamide