title: First principles design of derivatizing agent for direct determination of enantiomeric purity of chiral alcohols and amines by NMR spectroscopy.
abstract: (77)Se NMR offers superior sensing of chirality within the structure of the diastereomers (Deltadelta up to 6.1 ppm), compared to (13)C (Deltadelta < 1 ppm) and (1)H (Deltadelta < 0.2 ppm). The developed procedure is equally well suitable for determination of the enantiomeric purity of chiral alcohols and amines as pure samples as well as reaction mixtures and crude products.
authors.affiliation: Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Pr. 47, Moscow, 119991, Russia.
authors.forename: Nikolay V
authors.initials: NV
authors.lastname: Orlov
authors.forename: Valentine P
authors.initials: VP
authors.lastname: Ananikov