title: A 61-year-old woman with osteomalacia and a thoracic spine lesion.
abstract: Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative.
authors.forename: Ann E
authors.initials: AE
authors.lastname: Marshall
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Martin
authors.forename: Narasimhan P
authors.initials: NP
authors.lastname: Agaram
authors.forename: Jey-Hsin
authors.initials: JH
authors.lastname: Chen
authors.forename: Eric M
authors.initials: EM
authors.lastname: Horn
authors.forename: Annette C
authors.initials: AC
authors.lastname: Douglas-Akinwande
authors.forename: Eyas M
authors.initials: EM
authors.lastname: Hattab
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018193:Neoplasms, Complex and Mixed / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D009372:Neoplasms, Connective Tissue / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D010018:Osteomalacia / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D013125:Spinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D013904:Thoracic Vertebrae