title: [Pancreatic-duodenectomy for invasive colon cancer in a patient with Lynch syndrome. Case report.].
abstract: Despite the screening efforts in the general population and particularly in families with hereditary colon cancer, locally advanced colon cancer remains a common clinical problem. In block resection is considered mainstay therapy in these patients. The aim of this report is to present a case of right-sided colon cancer with a medullar phenotype invading the duodenum treated through in block resection. A case of a 54-year-old male with a family history of colon and pancreatic cancer with lower gastrointestinal tract bleeding is presented. Colonoscopy and computed tomography scan showed a tumor in the colonic hepatic flexure invading the duodenum. The patient underwent an in block resection of the right colon, duodenum, pancreas and antrum. The histopathological study showed a T4N0M0 adenocarcinoma invading the duodenum, pancreas and antrum with negative margins. His postoperative evolution was complicated with a pancreatic fistula, which resolved with conservative measures. In conclusion, in block resection is the treatment of choice for locally advanced colon cancer with invasion to duodenum and pancreas and should be performed in high-volume centers familiar with this type of procedures. Key words: pancreaticoduodenectomy, colon cancer, Lynch syndrome, pancreas, surgery, Mexico.
authors.affiliation: Departamento de Cirugía. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, DF.
authors.forename: O
authors.initials: O
authors.lastname: Vergara-Fernández
authors.forename: D
authors.initials: D
authors.lastname: Zamora-Valdés
authors.forename: H A
authors.initials: HA
authors.lastname: Rodríguez-Zentner
authors.forename: H
authors.initials: H
authors.lastname: Tapia
authors.forename: N
authors.initials: N
authors.lastname: Sánchez-Fernández
authors.forename: A
authors.initials: A
authors.lastname: Gamboa-Domínguez
authors.forename: H
authors.initials: H
authors.lastname: Medina-Franco
authors.forename: C
authors.initials: C
authors.lastname: Chan-Núñez
mesh_terms: D000328:Adult; D003110:Colonic Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D016577:Pancreaticoduodenectomy