A family with leukonychia totalis.
A family presented to our dermatology clinic with a complaint of white nails. Physical examination revealed clinical feature of leukonychia totalis and the presence of sensorineural hearing loss, palmo plantar keratoderma and knuckle pads (four essential criteria for the diagnosis of Bart Pumphrey syndrome).Three consecutive generations of this family were affected with variable presentations of Bart Pumphrey syndrome in male and female; and autosomal dominant pattern of inheritance.
Balighi
Kamran
K
Departement of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Moeineddin
Fatemeh
F
Lajevardi
Vahideh
V
Ahmadreza
Rajaee
R