title: Covalently linked deoxyribonucleic acid with multi-walled carbon nanotubes: synthesis and characterization.
abstract: In this chapter, a multi-step protocol for covalently linking functionalized multi-walled carbon nanotubes (MWCNT) to deoxyribonucleic acid (DNA) oligonucleotides is provided. X-ray photoelectron spectroscopy (XPS) is used to characterize the initially formed amine-terminated MWCNTs, to which DNA is covalently anchored. Atomic force microscopy (AFM) investigation of the DNA-MWCNT conjugates reveals that the chemical functionalization occurs at both the ends and sidewalls of the nanotubes. The described methodology represents an important step toward the realization of DNA-guided self-assembly for carbon nanotubes.
authors.affiliation: Department of Physics & Materials Science, City University of Hong Kong, Hong Kong, KLT, Hong Kong.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Chen
authors.forename: Changqing
authors.initials: C
authors.lastname: Yi
authors.forename: Tzang
authors.initials: T
authors.lastname: Chi-Hung
authors.forename: Shuit-Tong
authors.initials: ST
authors.lastname: Lee
authors.forename: Mengsu
authors.initials: M
authors.lastname: Yang
mesh_terms: D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D037742:Nanotubes, Carbon / Q000737:chemistry*; D013053:Spectrophotometry; D014965:X-Rays
chemical_list: D037742:Nanotubes, Carbon; D004247:DNA