[Clinical manifestation of spinal tumours after a trauma.].
Medullary tumours manifest themselves clinically after a certain asymptomatic period. This period is characterized by the oedema of spinal cord and the disorder of microcirculation at the level of compression. After a trauma of the back there occur biochemical processes which result among others in the accumulation of calcium ions and in the activation of metabolism of arachidonic acid and thus in an increased synthesis of prostanoids. These agents lead up to the deterioration of vasogenous oedema at the level of compression and the tumour clinically manifests itself in connection with the trauma. The author analyzed a group of 66 patients with a medullary tumour and in 6 patients of the group she has found out the above mentioned connection. She presents case reports of 6 patients in which there occured the clinical manifestation of the spinal tumour in a relatively short interval after the trauma. The mentioned mechanism of manifestation was found mainly in men of younger age groups. Sports and traffic injuries predominated. From the histological aspect vascularized tumours were involved, mostly semi-malignant or malignant by nature. Key words: trauma, spinal tumours.
Grammetbauerová
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Neurologická klinika 3. lékarské fakulty KU.