title: CGHnormaliter: a Bioconductor package for normalization of array CGH data with many CNAs.
abstract: CONCLUSIONS
  CGHnormaliter is a package for normalization of array comparative genomic hybridization (aCGH) data. It uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). CGHnormaliter is integrated in the Bioconductor environment allowing a smooth link to visualization tools and further data analysis.
  
  
  METHODS
  The CGHnormaliter package is implemented in R and under GPL 3.0 license available at Bioconductor: http://www.bioconductor.org
  
  
  BACKGROUND
  heringa@few.vu.nl
authors.affiliation: Centre for Integrative Bioinformatics VU, VU University Amsterdam, De Boelelaan 1081A, 1081 HV Amsterdam, The Netherlands.
authors.forename: Bart P P
authors.initials: BP
authors.lastname: van Houte
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Binsl
authors.forename: Hannes
authors.initials: H
authors.lastname: Hettling
authors.forename: Jaap
authors.initials: J
authors.lastname: Heringa
mesh_terms: D055028:Comparative Genomic Hybridization / Q000379:methods*; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D012984:Software