title: Sensor for fisetin based on gold nanoparticles in ionic liquid and binuclear nickel complex immobilized in silica.
abstract: Gold nanoparticles dispersed in an ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate (Au-BMI.PF(6)) and a binuclear nickel(II) complex ([Ni(2)(HBPPAMFF)mu-(OAc)(2)(H(2)O)]BPh(4)) immobilized on functionalized silica were successfully applied in the construction of a novel sensor for the determination of fisetin by square-wave voltammetry. Under optimized conditions, the analytical curve showed two linear ranges for fisetin concentrations from 0.28 to 1.39 microM and 2.77 to 19.50 microM with a detection limit of 0.05 microM. This sensor demonstrated suitable stability (ca. 150 days; at least 500 determinations) and good repeatability and reproducibility, with relative standard deviations of 2.91 and 5.11%, respectively. The recovery study of fisetin in apple juice samples gave values from 96.4 to 106.4%. The efficient analytical performance of the proposed sensor can be attributed to the effective immobilization of the Ni(ii)Ni(ii) complex on silica and the Au-BMI.PF(6) contribution to the electrode response.
authors.affiliation: Laboratory of Biosensors, Department of Chemistry, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil. danielabrondani@hotmail.com
authors.forename: Daniela
authors.initials: D
authors.lastname: Brondani
authors.forename: Iolanda Cruz
authors.initials: IC
authors.lastname: Vieira
authors.forename: Clovis
authors.initials: C
authors.lastname: Piovezan
authors.forename: Jaqueline Maria
authors.initials: JM
authors.lastname: Ramos da Silva
authors.forename: Ademir
authors.initials: A
authors.lastname: Neves
authors.forename: Jairton
authors.initials: J
authors.lastname: Dupont
authors.forename: Carla Weber
authors.initials: CW
authors.lastname: Scheeren
mesh_terms: D002384:Catalysis; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005419:Flavonoids / Q000032:analysis*; D044948:Flavonols; D006046:Gold / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: C412621:1-butyl-3-methylimidazolium hexafluorophosphate; D005419:Flavonoids; D044948:Flavonols; D007093:Imidazoles; D052578:Ionic Liquids; D006046:Gold; D012822:Silicon Dioxide; D009532:Nickel; C017875:fisetin