title: [Clinical experience of 371 cases of sphincter-preservation with telescopic anastomosis after radical excision for low-middle rectal cancer].
abstract: OBJECTIVE
  To evaluate the clinical efficacy, feasibility and safety of sphincter-preservation with telescopic anastomosis of colon and rectal mucosa in low-middle rectal cancer.
  
  
  METHODS
  A retrospective analysis was carried out in 371 patients with low-middle rectal cancer in whom telescopic anastomosis was used. There were 224 males and 147 females, with a mean age of 57.9 (21-99) years. The lower margins of the tumors located between 5-8 cm from the anal verge. On histopathology, there were 361 adenocarcinomas, including 138 well-differentiated, 201 moderately differentiated, 11 poorly differentiated, 11 mucinous adenocarcinoma, and 10 adenomas with neoplastic changes. According to the Duke's stage classification, 120 were TNM stage I, 222 stage II, 26 stage III, and 3 stage IV.
  
  
  RESULTS
  Three hundred and eighteen (318/371, 85.7%) cases were followed up, and the median follow up time was 5.8 years. Postoperative complications were observed, including 16(4.3%) cases with anastomotic leak, and 8 (2.1%) with anastomotic stenosis. All the patients resumed normal bowel function during 12-24 weeks after operation, with 1-3 times per day. The local recurrence rate was 6.3% (20/318). Hepatic and lung metastasis was 14.5% (46/318) and 2.5% (8/318), respectively. The 5-year survival rate was 69.7%.
  
  
  CONCLUSIONS
  The sphincter-preservation with telescopic anastomosis procedure is safe and effective for low-middle rectal cancer, and the sphincter function can be well-preserved.
authors.affiliation: Department of General Surgery, Beijing Army General Hospital, Beijing 100700, China. lsybz@126.com
authors.forename: Shi-yong
authors.initials: SY
authors.lastname: Li
authors.forename: Zhen-jia
authors.initials: ZJ
authors.lastname: Liang
authors.forename: Shu-jun
authors.initials: SJ
authors.lastname: Yuan
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Fu-yi
authors.initials: FY
authors.lastname: Zuo
authors.forename: Xue
authors.initials: X
authors.lastname: Bai
authors.forename: Guang
authors.initials: G
authors.lastname: Chen
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Wei
authors.forename: Yi-shi
authors.initials: YS
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Cui
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult