title: Automating and simplifying the SOFA score in critically ill patients with cancer.
abstract: The aim was to demonstrate the performance of a modified version of the Sequential Organ Failure Assessment (SOFA) score to predict mortality in medical and surgical patients with cancer. We performed an electronic retrospective review of databases. We included adult patients with cancer admitted into a 53-bed ICU over 28 months. We electronically calculated a modified SOFA (mSOFA) score at admission. A majority of the patients were admitted into the surgical ICU. Of 328 nonsurvivors, 85.1 per cent were medical patients and only 14.9 per cent surgical patients. The mean admission mSOFA scores for medical and surgical patients were 4.7 +/- 3.2 and 1.7 +/- 1.9, respectively. The overall area under the curve (AUC) of the mSOFA score was 0.84. The AUCs for medical and surgical patients were 0.72 and 0.78, respectively. Our results demonstrate that electronic assessment of mSOFA score has potential in resource allocation decisions as well as in critical care outreach programs.
authors.affiliation: Department of Critical Care Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. jlnates@mdanderson.org
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Nates
authors.forename: Marylou
authors.initials: M
authors.lastname: Cárdenas-Turanzas
authors.forename: Chris
authors.initials: C
authors.lastname: Wakefield
authors.forename: Susannah
authors.initials: S
authors.lastname: Kish Wallace
authors.forename: Andrew
authors.initials: A
authors.lastname: Shaw
authors.forename: Joshua A
authors.initials: JA
authors.lastname: Samuels
authors.forename: Joe
authors.initials: J
authors.lastname: Ensor
authors.forename: Kristen J
authors.initials: KJ
authors.lastname: Price
mesh_terms: D000328:Adult; D000465:Algorithms; D019540:Area Under Curve; D016638:Critical Illness / Q000145:classification*; D001330:Electronic Data Processing; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000175:diagnosis* / Q000601:surgery; D009369:Neoplasms / Q000145:classification* / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012984:Software