title: The identification and distribution of progesterone receptors in the brain and thoracic ganglion in the mud crab Scylla paramamosain (Crustacea: Decapoda: Brachyura).
abstract: The existence of progesterone receptors (PR) in the Scylla paramamosain (mud crab) was studied using immunological techniques. By Western blotting, PR with an apparent molecular weight of 70 kDa is identified in both the brain and the thoracic ganglion. By immunohistochemistry, PR immunoreactive neurons are detected mainly in the protocerebrum, the subesophageal ganglion and the leg ganglion. PR immunoreactivity is localized mainly in the nuclei of these neurons, while only a few neurons show such activities in their cytoplasm. Our results provide evidence that progesterone modulates the neuroendocrine system mainly via nucleus receptors.
authors.affiliation: Department of Oceanography, State Key Laboratory of Marine Environmental Science, Xiamen University, 361005, Xiamen, China. haihuiye@xmu.edu.cn
authors.forename: Haihui
authors.initials: H
authors.lastname: Ye
authors.forename: Huiyang
authors.initials: H
authors.lastname: Huang
authors.forename: Ping
authors.initials: P
authors.lastname: Song
authors.forename: Guizhong
authors.initials: G
authors.lastname: Wang
mesh_terms: D000818:Animals; D015153:Blotting, Western; D003386:Brachyura / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D005260:Female; D045888:Ganglion Cysts; D007150:Immunohistochemistry; D009474:Neurons / Q000378:metabolism; D011980:Receptors, Progesterone / Q000032:analysis* / Q000378:metabolism
chemical_list: D011980:Receptors, Progesterone