title: Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer.
abstract: OBJECTIVE
  The aim of this study was to compare magnetic resonance imaging (MRI) with positron emission tomography/computed tomography (PET/CT) in the preoperative detection of lymph node metastases in patients with uterine cervical cancer.
  
  
  METHODS
  This retrospective study reviewed patients with cervical cancer who had undergone both preoperative MRI and PET/CT before radical surgery, including lymphadenectomy between 2004-2008.
  
  
  RESULTS
  Eighty-three patients were identified, of whom 28 (33.7%) had pelvic lymph node metastasis. The sensitivity, specificity, and accuracy for detecting lymph node metastasis were 64.3%, 69.1%, and 67.5% for MRI, and 28.6%, 83.6%, and 65.1% for PET/CT, respectively. The area under the receiver operating characteristics for the MRI and PET/CT were 0.667 and 0.561, respectively (P = .013). MRI showed significantly higher sensitivity for detecting metastatic lymph nodes than PET/CT (P = .006).
  
  
  CONCLUSIONS
  MRI was more sensitive than PET/CT for detecting metastatic lymph node in patients with cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Hyun Hoon
authors.initials: HH
authors.lastname: Chung
authors.forename: Keon Wook
authors.initials: KW
authors.lastname: Kang
authors.forename: Jeong Yeon
authors.initials: JY
authors.lastname: Cho
authors.forename: Jae Weon
authors.initials: JW
authors.lastname: Kim
authors.forename: Noh-Hyun
authors.initials: NH
authors.lastname: Park
authors.forename: Yong-Sang
authors.initials: YS
authors.lastname: Song
authors.forename: Seung Hyup
authors.initials: SH
authors.lastname: Kim
authors.forename: June-Key
authors.initials: JK
authors.lastname: Chung
authors.forename: Soon-Beom
authors.initials: SB
authors.lastname: Kang
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011300:Preoperative Care / Q000379:methods; D011336:Probability; D012372:ROC Curve; D012189:Retrospective Studies; D012380:Role; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D055815:Young Adult