title: Intraoral sclerosing perineurioma: a case report and review of the literature.
abstract: Sclerosing perineurioma is an extraneural soft tissue lesion that has been reported in the extremities of young adults. It is composed of oval epithelioid or plump spindled cells scattered to form ill-defined fascicles in a storiform, whorled, or trabecular pattern and dermal sclerosis represented by thickened collagen bundles in a lamellar array that express epithelial membrane antigen and are negative for S-100 protein. The treatment is surgical excision, and no recurrence or metastases are expected. Herein is presented the first case of intraoral sclerosing perineurioma of the lower lip, emphasizing its histopathologic and immunohistochemical features.
authors.affiliation: Oral Diagnosis Department, Semiology and Oral Pathology, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
authors.forename: Wilfredo Alejandro
authors.initials: WA
authors.lastname: González-Arriagada
authors.forename: Jorge Esquiche
authors.initials: JE
authors.lastname: Leon
authors.forename: Pablo Agustin
authors.initials: PA
authors.lastname: Vargas
authors.forename: Oslei
authors.initials: O
authors.lastname: Paes de Almeida
authors.forename: Marcio Ajudarte
authors.initials: MA
authors.lastname: Lopes
mesh_terms: D000328:Adult; D003094:Collagen; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000175:diagnosis; D008048:Lip Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D018396:Mucin-1 / Q000032:analysis; D009078:Mucocele / Q000175:diagnosis; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis; D012598:Sclerosis; D014746:Vimentin / Q000032:analysis
chemical_list: D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin; D003094:Collagen