title: A cluster of Legionnaires' disease and associated Pontiac fever morbidity in office workers, Dublin, June-July 2008.
abstract: In June and July 2008, two office workers were admitted to a Dublin hospital with Legionnaires' disease. Investigations showed that cooling towers in the basement car park were the most likely source of infection. However, positive results from cooling tower samples by polymerase chain reaction (PCR) did not correlate with subsequent culture results. Also, many employees reported Pontiac fever-like morbidity following notification of the second case of Legionnaires' disease. In total, 54 employees attended their general practitioner or emergency department with symptoms of Legionnaires' disease or Pontiac fever. However, all laboratory tests for Legionnaires' disease or Pontiac fever were negative. In this investigation, email was used extensively for active case finding and provision of time information to employees and medical colleagues. We recommend clarification of the role of PCR in the diagnosis of legionellosis and also advocate for a specific laboratory test for the diagnosis of the milder form of legionellosis as in Pontiac fever.
authors.affiliation: Department of Public Health, Health Services Executive, Dublin, Ireland. mary.wardbarrett@hse.ie
authors.forename: M
authors.initials: M
authors.lastname: Ward
authors.forename: M
authors.initials: M
authors.lastname: Boland
authors.forename: N
authors.initials: N
authors.lastname: Nicolay
authors.forename: H
authors.initials: H
authors.lastname: Murphy
authors.forename: J
authors.initials: J
authors.lastname: McElhiney
authors.forename: C
authors.initials: C
authors.lastname: Collins
authors.forename: M
authors.initials: M
authors.lastname: Lynch
authors.forename: M
authors.initials: M
authors.lastname: McCarthy
authors.forename: J
authors.initials: J
authors.lastname: O' Donnell
mesh_terms: D000389:Air Conditioning; D004196:Disease Outbreaks; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D016952:Legionella pneumophila / Q000235:genetics / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D016133:Polymerase Chain Reaction; D014871:Water Microbiology