[Research on formulation process of yisheng capsule].
OBJECTIVE
To choose the best supplementary material and formulation process of Yisheng capsules.


METHODS
The angle of repose, hygroscopicity and critical relative humidity were used as the indices to choose the formulation process of Yisheng capsules.


RESULTS
The best technique conditions were as follows: the extract powder and microcrystalline cellulose were mixed in proportion of 2:1, the 95% alcohol was used as the wetting agent.


CONCLUSIONS
The formulation process is rational and practicable.
Lei
Jian
J
Department of Pharmacy, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China. fengxiao218@163.com
Xing
Mao
M
Hu
Xue-lian
XL
Zhang
En-juan
EJ
Peng
Yi
Y
D002214:Capsules; D002482:Cellulose / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry; D005079:Excipients / Q000737:chemistry; D006813:Humidity; D010946:Plants, Medicinal / Q000737:chemistry; D011208:Powders; D013678:Technology, Pharmaceutical / Q000379:methods*
D002214:Capsules; D004365:Drugs, Chinese Herbal; D005079:Excipients; D011208:Powders; D000431:Ethanol; D002482:Cellulose; C109691:microcrystalline cellulose