title: Epidermoid cancers of the anal canal: current treatment.
abstract: Epidermoid carcinoma of the anal canal is an uncommon disease, but has increased in incidence with the HIV epidemic. Prior to the 1970s, treatment consisted of radical surgery with abdominoperineal resection. With the pioneering work of Dr. Norman Nigro, this has shifted to a nonsurgical approach, with primary treatment consisting of multimodality therapy with radiation and chemotherapy. This review provides an overview of the historical, current, and future treatments of epidermoid anal canal malignancies.
authors.affiliation: Division of Colon and Rectal Surgery, Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Blumetti
authors.forename: Amir L
authors.initials: AL
authors.lastname: Bastawrous