[Antibodies to Collagen in the Patients with primary Operation and Reoperation of Endoprosthesis of the Hip Joint.].
Using ELISA method titres were determined of antibodies to collagen of type I, II and III in the serum of the patients who underwent implantation or reoperation of total endoprosthesis of the hip joint. The group of primary operations included mainly patients with osteoarthritis (OA), ankylosing spondyllitistis (AS), rheumatoid arthritis (RA), the group of the reoperated comprised also patients after various traumas of the hip joint. Increased titres were generally found in all patients, however, in the group of reoperated patients the average values were higher than in the patients after primary operations. In the reoperated patients the level of antibodies against all types of collagen monitored was statistically significantly increased in comparison with the control group both prior to and after the surgical operation, mainly in type II. The patients before the primary operation have the levels of antibodies against collagen type II significantly increased in comparison with the controls. The increase found may be caused by the primary articular disease - inflammatory changes, which were found also in decompensated OA. Key words: hip joint replacement, reoperation, collagen, antibodies.
Becvár
R
R
Revmatologický ústav, Praha.
Novotná
J
J
Krbec
M
M
Cech
O
O
Adam
M
M