[Influence of some simple phenols on biochemical and morphological indices of rat blood].
Influence of various doses of xenobiotics on several biological and morphological indices of rat blood has been studied. It was established that intraperitoneal injections of the investigated phenols resulted in effect on biochemical indices of rat blood, specific to the particular phenolic compound. The strongest effect was observed in case of 4-nitrophenol and the weakest one was in case of hydroquinone; it witnesses for strong toxicity of 4-nitrophenol and for antioxidant properties of hydroquinone. Influence of various doses of phenol, 4-nitrophenol and hydroquinone on change of structural indices of the constituents of blood has been studied. Importance of the immune system for selection of adaptation pathways of organism has been demonstrated. Correlation between enteral concentration of the investigated phenols and several biochemical and morphological indices of blood has been established.
Arziani
B A
BA
Chikhladze
Ts K
TsK
Gumbaridze
N G
NG
Lekishvili
G N
GN
D000818:Animals; D001772:Blood Cell Count; D001773:Blood Cells / Q000187:drug effects*; D001786:Blood Glucose / Q000187:drug effects*; D004785:Environmental Pollutants / Q000633:toxicity*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D010636:Phenols / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D004785:Environmental Pollutants; D008077:Lipoproteins, LDL; D010636:Phenols