title: Surgical management of articular cartilage defects in the knee.
abstract: The treatment of isolated cartilage lesions of the knee is based on several underlying principles, including a predictable reduction in the patient's symptoms, improvements in function and joint congruence, and prevention of progressive damage. Surgical options for cartilage restoration are described as palliative treatments, such as débridement and lavage; reparative, such as marrow stimulation techniques; or restorative, such as osteochondral grafting and autologous chondrocyte implantation. The choice of an appropriate treatment should be made on an individual basis, with consideration for the patient's specific goals (such as pain reduction or functional improvement), physical demand level, prior treatment history, lesion size and location, and a systematic evaluation of the knee that considers comorbidities, including alignment, meniscal status, and ligament integrity. It is important for the physician to be familiar with the indications, surgical techniques, and clinical outcomes of the available treatment options for chondral defects of the knee.
authors.affiliation: Department of Orthopedics, Cartilage Restoration Center at Rush, Rush University Medical Center, Chicago, Illinois, USA.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Cole
authors.forename: Cecilia
authors.initials: C
authors.lastname: Pascual-Garrido
authors.forename: Robert C
authors.initials: RC
authors.lastname: Grumet
mesh_terms: D000465:Algorithms; D016026:Bone Marrow Transplantation; D002357:Cartilage Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002358:Cartilage, Articular; D019902:Chondrocytes / Q000637:transplantation; D003646:Debridement; D050724:Fractures, Cartilage / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007719:Knee Joint; D019637:Orthopedic Procedures