title: Serial measurement of Therapeutic Intervention Scoring System-28 (TISS-28) in a surgical intensive care unit.
abstract: OBJECTIVE
  The aim of the study was to assess the use of the Therapeutic Intervention Scoring System-28 (TISS-28) in surgical intensive care unit (ICU) patients and the relationship of the score to the type of surgery, severity of illness, and outcome in these patients.
  
  
  METHODS
  Prospectively collected data from all patients admitted to a postoperative ICU between March 1, 2004, and June 30, 2006, were analyzed retrospectively.
  
  
  RESULTS
  A total of 6903 patients were admitted during the study period (63.5% male; mean age, 62.3 years) constituting 29 140 observation days. The mean Simplified Acute Physiology Score (SAPS) II, Sequential Organ Failure Assessment (SOFA), and TISS-28 scores on the day of ICU admission were 36.9 ± 18.2, 5.8 ± 3.9, and 43.2 ± 10.8, respectively. The highest admission TISS-28 was observed in patients who underwent cardiothoracic surgery (47.7 ± 10.1), the lowest in neurosurgical patients (40 ± 9.6), and both declined during the 2 weeks after ICU admission; however, in trauma patients and those admitted after gastrointestinal surgery, TISS scores increased gradually after the first 2 to 5 days in the ICU. The TISS-28 score was moderately correlated to SAPS II (R(2) = 0.42; P < .001) and SOFA score (R(2) = 0.48; P < .001) throughout the ICU stay and was consistently higher in nonsurvivors than in survivors during the first 2 weeks in the ICU.
  
  
  CONCLUSIONS
  There are marked variations in TISS-28 scores according to the type of surgery. Therapeutic Intervention Scoring System-28 correlates with the severity of illness and outcome in these patients.
authors.affiliation: Department of Anesthesiology and Intensive Care, Friedrich-Schiller University Hospital, Jena 07743, Germany.
authors.forename: Norman
authors.initials: N
authors.lastname: Muehler
authors.forename: Janaina
authors.initials: J
authors.lastname: Oishi
authors.forename: Martin
authors.initials: M
authors.lastname: Specht
authors.forename: Florian
authors.initials: F
authors.lastname: Rissner
authors.forename: Konrad
authors.initials: K
authors.lastname: Reinhart
authors.forename: Yasser
authors.initials: Y
authors.lastname: Sakr
mesh_terms: D000368:Aged; D003422:Critical Care; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013514:Surgical Procedures, Operative / Q000145:classification* / Q000401:mortality; D016896:Treatment Outcome