Selective functionalization of a single methylene bridge of a calix[6]arene.
The monohydroxycalix[6]arene derivative 4a was prepared via photochemical bromination of hexamethoxycalix[6]arene 3a in aq THF. Monohydroxycalix[6]arene 4a and its chloro derivative 5 are useful synthetic intermediates for the preparation of structurally diverse calix[6]arenes functionalized at a single methylene bridge.
Itzhak
Norbert
N
Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Biali
Silvio E
SE
D047250:Calixarenes / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry; D010777:Photochemistry
D010636:Phenols; C476540:calix(6)arene; D047250:Calixarenes