Determining the expression rate of the IgM and IgA in B cell lymphomas by immunohistochemistry.
This study aimed at assessing the expression rate of IgA and IgM in B cell lymphoma immunohistochemically. Paraffin-embedded specimens of NHL evaluated for presence of CD20 by immunohistochemical staining and then, the positive cases were again immunohistochemically assessed for expression of IgM and IgA. Fifty two paraffin-embedded specimens evaluated. Thirty six cases (69.2%) were positive for the CD20. The mean age of these patients (CD20+ cases) was 50.0 +/- 23.6 years. Twenty two cases (61%) were male and 14 cases (39%) were female. The frequency of the IgM+, IgA+ and IgA/IgM+ (simultaneous) cases was 15 (41.7%), 9 (25%) and 4 (11.1%), respectively. The current rates are in the range of similar reports in the literature.
Fakhrjou
A
A
Department of Pathology, Ward of Pathology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Bozorgi
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007075:Immunoglobulin M / Q000276:immunology*; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
D007070:Immunoglobulin A; D007075:Immunoglobulin M