title: Refractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: a case report.
abstract: We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis.
authors.affiliation: Department of Gastroenterology, Aichi Cancer Center Aichi Hospital, Okazaki City, Aichi 444-0011, Japan.
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Fujita
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ando
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Sakakibara
authors.forename: Waki
authors.initials: W
authors.lastname: Hosoda
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto
mesh_terms: D000368:Aged; D005756:Gastritis / Q000150:complications / Q000188:drug therapy; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism*; D008297:Male; D010950:Plasma Cells / Q000276:immunology* / Q000473:pathology; D012598:Sclerosis; D013276:Stomach Ulcer / Q000209:etiology / Q000276:immunology* / Q000473:pathology
chemical_list: D007074:Immunoglobulin G