title: Hospital acquired outbreak of methicillin-resistant Staphylococcus aureus infection initiated by a health care worker.
abstract: BACKGROUND
  Methicillin-resistant Staphylococcus aureus (MRSA) has become an increasingly important pathogen leading to hospital acquired infections.
  
  
  OBJECTIVE
  This study was done to confirm an outbreak of MRSA suspected at Charles Nicolle Hospital.
  
  
  METHODS
  From 26 April to 11 June 2002, six patients hospitalized in the dermatologic ward at Charles Nicolle hospital of Tunisia have developed infections caused by MRSA. An investigation of the outbreak has been detected a nasal carriage nurse. This carrier received topical mupirocin treatment to decolonize the anterior nares and the outbreak was stopped without further incident.
  
  
  RESULTS
  Typing of the MRSA strains by pulsed field gel electrophoresis demonstrated the same pulsotype shared by all isolates showing that MRSA isolates belonged to a single clonal type responsible of outbreak. Colonized nurse was the source of MRSA dissemination.
  
  
  CONCLUSIONS
  This report illustrates the risk of nosocomial outbreak linked to cares delivered by the staff personnel. More sensibilisation and the respect of strict hygienic measures should be emphasized.
authors.affiliation: Laboratoire de Recherche Résistance aux Antimicrobiens, Faculté de Médecine de Tunis.
authors.forename: Salima
authors.initials: S
authors.lastname: Ben Ayed
authors.forename: Ilhem
authors.initials: I
authors.lastname: Boutiba-Ben Boubaker
authors.forename: Jalel
authors.initials: J
authors.lastname: Boukadida
authors.forename: Samia
authors.initials: S
authors.lastname: Hammami
authors.forename: Saïda
authors.initials: S
authors.lastname: Ben Redjeb
mesh_terms: D003428:Cross Infection / Q000175:diagnosis*; D006801:Humans; D017757:Infectious Disease Transmission, Professional-to-Patient; D055624:Methicillin-Resistant Staphylococcus aureus; D009296:Nasal Cavity / Q000382:microbiology; D009741:Nursing Staff, Hospital; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000635:transmission*; D014416:Tunisia