title: A bioorthogonal chemistry strategy for probing protein lipidation in live cells.
abstract: We report a chemical lipidation model for the study of protein lipidations in vitro and in live mammalian cells based on a bioorthogonal, photoinduced tetrazole-alkene cycloaddition reaction.
authors.affiliation: Department of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA.
authors.forename: Wenjiao
authors.initials: W
authors.lastname: Song
authors.forename: Zhipeng
authors.initials: Z
authors.lastname: Yu
authors.forename: Michael M
authors.initials: MM
authors.lastname: Madden
authors.forename: Qing
authors.initials: Q
authors.lastname: Lin
mesh_terms: D004591:Electrophoresis, Polyacrylamide Gel; D049452:Green Fluorescent Proteins / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D015394:Molecular Structure; D010777:Photochemistry / Q000379:methods; D011506:Proteins / Q000737:chemistry*; D013777:Tetrazoles / Q000737:chemistry*
chemical_list: D011506:Proteins; D013777:Tetrazoles; C485184:enhanced green fluorescent protein; D049452:Green Fluorescent Proteins; C045574:1H-tetrazole