Use of narrow-band imaging bronchoscopy in detection of lung cancer.
Narrow-band imaging (NBI) is a new endoscopic technique designed for detection of pathologically altered submucosal and mucosal microvascular patterns. The combination of magnification videobronchoscopy and NBI showed great potential in the detection of precancerous and cancerous lesions of the bronchial mucosa. The preliminary studies confirmed supremacy of NBI over white-light videobronchoscopy in the detection of premalignant and malignant lesions. Pathological patterns of capillaries in bronchial mucosa are known as Shibuya's descriptors (dotted, tortuous and abrupt-ending blood vessels). Where respiratory endoscopy is concerned, the NBI is still a 'technology in search of proper indication'. More randomized trials are necessary to confirm the place of NBI in the diagnostic algorithm, and more trials are needed to evaluate the relation of NBI to autofluorescence videobronchoscopy and to white-light magnification videobronchoscopy. Considering the fact that NBI examination of the tracheo-bronchial tree is easy, reproducible and clear to interpret, it is certain that NBI videobronchoscopy will play a significant role in the future of lung cancer detection and staging.
Zaric
Bojan
B
Institute for Pulmonary Diseases of Vojvodina, Clinic for Pulmonary Oncology, Institutski put 4, Sremska Kamenica, Serbia. bojanzaric@neobee.net
Perin
Branislav
B
D000818:Animals; D001999:Bronchoscopy / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*