What can we learn from an unnatural immune response?
In a recent review on CD8+ T-cell responses after malaria infection and immunization, Zavala and colleagues outline two decades of research and formulate the central unresolved questions in the field. Here we discuss some of these findings and highlight their importance to malaria vaccinology.
Bennett
Brandy Lee
BL
Department of Medical Parasitology, New York University School of Medicine, New York, NY 10010, USA.
Sinnis
Photini
P
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology* / Q000469:parasitology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D017780:Malaria Vaccines / Q000276:immunology*; D016778:Malaria, Falciparum / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control; D010963:Plasmodium falciparum / Q000276:immunology*
D017780:Malaria Vaccines