Harnessing CD8(+) regulatory T cells: therapy for type 1 diabetes?
In this issue of Immunity, Tsai et al. (2010) demonstrate that low-avidity autoantigen-specific regulatory CD8(+) T cells can reverse ongoing autoimmune disease and provide insight into the mechanism by which this is achieved.
Zaccone
Paola
P
Department of Pathology, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QP, UK.
Cooke
Anne
A