Fetal valproate syndrome in a 2-month-old male infant.
Fetal valproate syndrome (FVS) results from prenatal exposure to valproic acid. It is characterized by a distinctive facial appearance, a cluster of minor and major anomalies and central nervous system dysfunction. We describe a 2-month-old male infant with the typical dysmorphic features characteristic of FVS. He had a persistent left superior vena cava draining into a dilated coronary sinus and mild pulmonary hypertension. There was a history of maternal intake of sodium valproate during pregnancy.
Zaki
Syed A
SA
Department of Pediatrics, Lokmanya Tilak Municipal General Hospital, Mumbai, India.
Phulsundar
Amol
A
Shanbag
Preeti
P
Mauskar
Anupama
A
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis*; D000927:Anticonvulsants / Q000009:adverse effects; D002493:Central Nervous System Diseases / Q000139:chemically induced / Q000151:congenital; D054326:Coronary Sinus / Q000002:abnormalities*; D019465:Craniofacial Abnormalities / Q000139:chemically induced* / Q000175:diagnosis; D005145:Face / Q000002:abnormalities; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced / Q000151:congenital* / Q000175:diagnosis; D007223:Infant; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D018570:Risk Assessment; D013577:Syndrome; D014635:Valproic Acid / Q000009:adverse effects*; D014683:Vena Cava, Superior / Q000002:abnormalities*
D000927:Anticonvulsants; D014635:Valproic Acid