Primary treatment of incomplete Kawasaki disease with infliximab and methylprednisolone in a patient with a contraindication to intravenous immune globulin.
Incomplete Kawasaki disease was diagnosed in a 3-year-old boy. Because intravenous immune globulin infusion was not tolerated, he was treated with infliximab and methylprednisolone. Coronary aneurysms were not visualized on initial or follow-up echocardiograms. To our knowledge, this is the first report to document the use of infliximab and methylprednisolone as first line therapy for Kawasaki disease.
Shirley
Debbie-Ann
DA
Pediatric Infectious Diseases and Tropical Pediatrics, University of Maryland Medical Center, Baltimore, MD, USA. dshirley@peds.umaryland.edu
Stephens
Ina
I
D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000175:diagnosis; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage*; D000069285:Infliximab; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
D000911:Antibodies, Monoclonal; D007155:Immunologic Factors; D000069285:Infliximab; D008775:Methylprednisolone