title: Early human bone response to laser metal sintering surface topography: a histologic report.
abstract: This histologic report evaluated the early human bone response to a direct laser metal sintering implant surface retrieved after a short period of healing. A selective laser sintering procedure using a Ti-6Al-4V alloy powder with a particle size of 25-45 microm prepared this surface topography. One experimental microimplant was inserted into the anterior mandible of a patient during conventional implant surgery of the jaw. The microimplant and surrounding tissues were removed after 2 months of unloaded healing and were prepared for histomorphometric analysis. Histologically, the peri-implant bone appeared in close contact with the implant surface, whereas marrow spaces could be detected in other areas along with prominently stained cement lines. The mean of bone-to-implant contact was 69.51%. The results of this histologic report suggest that the laser metal sintering surface could be a promising alternative to conventional implant surface topographies.
authors.affiliation: University of Varese, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Mangano
authors.forename: Adriano
authors.initials: A
authors.lastname: Piattelli
authors.forename: Susana
authors.initials: S
authors.lastname: d'Avila
authors.forename: Giovanna
authors.initials: G
authors.lastname: Iezzi
authors.forename: Francesco
authors.initials: F
authors.lastname: Mangano
authors.forename: Tatiana
authors.initials: T
authors.lastname: Onuma
authors.forename: Jamil Awad
authors.initials: JA
authors.lastname: Shibli
mesh_terms: D000497:Alloys; D003722:Dental Alloys; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D017267:Dental Prosthesis Design; D006358:Hot Temperature; D006801:Humans; D053844:Lasers, Solid-State; D008297:Male; D008334:Mandible; D008875:Middle Aged; D016348:Osseointegration; D013499:Surface Properties; D014025:Titanium
chemical_list: D000497:Alloys; D003722:Dental Alloys; D015921:Dental Implants; C031462:titanium alloy (TiAl6V4); D014025:Titanium