title: Lessons from photoreceptors: turning off g-protein signaling in living cells.
abstract: Phototransduction in retinal rods is one of the most extensively studied G-protein signaling systems. In recent years, our understanding of the biochemical steps that regulate the deactivation of the rod's response to light has greatly improved. Here, we summarize recent advances and highlight some of the remaining puzzles in this model signaling system.
authors.affiliation: Departments of Ophthalmology and Vision Science, University of California, Davis, California, USA. meburns@ucdavis.edu
authors.forename: Marie E
authors.initials: ME
authors.lastname: Burns
authors.forename: Edward N
authors.initials: EN
authors.lastname: Pugh
mesh_terms: D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism*; D051379:Mice; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology*; D014785:Vision, Ocular / Q000502:physiology*
chemical_list: D019204:GTP-Binding Proteins