The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease.
Backscattering interferometry enables the detection of syphilis antibody-antigen interactions in the presence of human serum, showing promise as a diagnostic tool for the serological diagnosis of infectious disease with potentially quantitative capabilities.
Kussrow
Amanda
A
Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.
Enders
Carolyn S
CS
Castro
Arnold R
AR
Cox
David L
DL
Ballard
Ronald C
RC
Bornhop
Darryl J
DJ
D000906:Antibodies / Q000097:blood / Q000276:immunology; D000941:Antigens / Q000097:blood / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007368:Interferometry / Q000379:methods*; D008027:Light; D013587:Syphilis / Q000097:blood / Q000175:diagnosis*; D013588:Syphilis Serodiagnosis / Q000379:methods*
D000906:Antibodies; D000941:Antigens; D007074:Immunoglobulin G