Temporal-based needle segmentation algorithm for transrectal ultrasound prostate biopsy procedures.
OBJECTIVE
Automatic identification of the biopsy-core tissue location during a prostate biopsy procedure would provide verification that targets were adequately sampled and would allow for appropriate intraprocedure biopsy target modification. Localization of the biopsy core requires accurate segmentation of the biopsy needle and needle tip from transrectal ultrasound (TRUS) biopsy images. A temporal-based TRUS needle segmentation algorithm was developed specifically for the prostate biopsy procedure to automatically identify the TRUS image containing the biopsy needle from a collection of 2D TRUS images and to segment the biopsy-core location from the 2D TRUS image.


METHODS
The temporal-based segmentation algorithm performs a temporal analysis on a series of biopsy TRUS images collected throughout needle insertion and withdrawal. Following the identification of points of needle insertion and retraction, the needle axis is segmented using a Hough transform-based algorithm, which is followed by a temporospectral TRUS analysis to identify the biopsy-needle tip. Validation of the temporal-based algorithm is performed on 108 TRUS biopsy sequences collected from the procedures of ten patients. The success of the temporal search to identify the proper images was manually assessed, while the accuracies of the needle-axis and needle-tip segmentations were quantitatively compared to implementations of two other needle segmentation algorithms within the literature.


RESULTS
The needle segmentation algorithm demonstrated a >99% accuracy in identifying the TRUS image at the moment of needle insertion from the collection of real-time TRUS images throughout the insertion and withdrawal of the biopsy needle. The segmented biopsy-needle axes were accurate to within 2.3 +/- 2.0 degrees and 0.48 +/- 0.42 mm of the gold standard. Identification of the needle tip to within half of the biopsy-core length (<10 mm) was 95% successful with a mean error of 2.4 +/- 4.0 mm. Needle-tip detection using the temporal-based algorithm was significantly more accurate (p < 0.001) than the other two algorithms tested, while the segmentation of the needle axis was not significantly different between the three algorithms.


CONCLUSIONS
The temporal-based needle segmentation algorithm accurately segments the location of the biopsy core from 2D TRUS images of clinical prostate biopsy procedures. The results for needle-tip localization demonstrated that the temporal-based algorithm is significantly more accurate than implementations of some existing needle segmentation algorithms within the literature.
Cool
Derek W
DW
Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5K8, Canada. dcool@imaging.robarts.ca
Gardi
Lori
L
Romagnoli
Cesare
C
Saikaly
Manale
M
Izawa
Jonathan I
JI
Fenster
Aaron
A
D000465:Algorithms; D001185:Artificial Intelligence; D001331:Automation; D001707:Biopsy, Needle / Q000379:methods*; D003201:Computers; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D013997:Time Factors; D014463:Ultrasonography