Colorectal cancer distribution in 220 Indian patients undergoing colonoscopy.
OBJECTIVE
Colorectal cancer is one of the major cancers in the developed world. The incidence of colorectal cancer is low in India. The aim of the present study was to describe the anatomical distribution and age at diagnosis of colorectal cancer in India.


METHODS
Retrospective descriptive analysis of anatomical distribution, age at diagnosis and demography of 220 cases (149 [67.7%] men) of adenocarcinoma of the colon or rectum diagnosed at colonoscopy over a period of five years.


RESULTS
The mean age at diagnosis was 58.4 years (SD 13.3; range 23-85 years). Twenty-eight (12.7%) cases were below the age of 40 years. The majority (31.8%) cases were aged between 61-70 years. Most of the tumors (n=163, 74%) were located distal to the splenic flexure. Multivariate logistic regression analysis showed that bleeding per rectum (OR 2.8; 95% CI 1.2-6.2) was associated with distal cancer, and palpable mass (OR 3.9; 95% CI 1.7-8.6) was associated with proximal cancer.


CONCLUSIONS
Almost one-third of the colorectal cancers in this series occurred in the seventh decade and were located distal to the splenic flexure.
Peedikayil
Musthafa Chalikandy
MC
Department of Gastroenterology, Amritha Institute of Medical Sciences And Research Center, Kochi, Kerala, 682 041, India. musthafacpdr@gmail.com
Nair
Prem
P
Seena
S M
SM
Radhakrishnan
Lakshmi
L
Sadasivan
Shine
S
Naryanan
V A
VA
Balakrishnan
V
V
D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D055815:Young Adult