A girl with Peters plus syndrome associated with myelomeningocele and chronic renal failure.
A girl was born with sclerocornea of the right eye, corneal staphyloma of the left eye and lumbar myelomeningocele. The myelomeningocele was repaired soon after birth. The corneal staphyloma was perforated during infancy. She received keratoplasty and achieved light perception. Her right kidney revealed multicystic dysplasia and was non-functioning at birth. She had neurogenic bladder, and her renal function deteriorated gradually. Peters plus syndrome was diagnosed based on anterior ocular segment anomalies, short stature, developmental delay and characteristic face. Anterior ocular segment anomalies are rare findings, but seem to be occasionally associated with spina bifida and renal anomalies. Myelomeningocele and chronic renal failure in patients with Peters plus syndrome have not been reported to our knowledge.
Motoyama
Osamu
O
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, Chiba, Japan. motoyan@basil.ocn.ne.jp
Arai
Hiroko
H
Harada
Ryoko
R
Hasegawa
Kei
K
Iitaka
Kikuo
K
D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000150:complications; D005124:Eye Abnormalities / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006130:Growth Disorders / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D019767:Maxillofacial Abnormalities / Q000150:complications; D008591:Meningomyelocele / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D021782:Multicystic Dysplastic Kidney / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013577:Syndrome