[Drug treatment of cardiovascular risk factors over six years of following the French DESIR cohort].
OBJECTIVE
To describe the treatment of cardiovascular risk factors within the context of a cohort study of adults, according to the risk estimated by the Framingham equation.


METHODS
This prospective study, DESIR, followed 1526 men and 1652 women for six years. At the time of the study's initiation, all participants were aged 35 to 65, and none were being treated for hypertension or dyslipemia. Treatments for hypertension and dyslipemia initiated during the study were analyzed according to categories of cardiovascular risk based on the Framingham scale.


RESULTS
At baseline, 24% of men and 5% of women had an estimated 10 years cardiovascular risk (for CHD) higher or equal to 10%. Three years later, only 19% of these men and 36% of these women had been treated, while 6% of men and 9% of women at risk < 10% had also been treated well. At six years, one third of men at high risk at baseline and/or at three years were treated, against half of the women.


CONCLUSIONS
Despite a significant effort to communicate the importance of addressing and treating the individual risk factors, the currently prescribed treatments remain inadequate, especially given the necessity to treat them based on the assessment of the overall cardiovascular risk.
Cogneau
Joël
J
Institut de Recherche en Médecine Générale, 7 passage Poncelet 75017 Paris, France.
Lebeau
Jean-Pierre
JP
Tichet
Jean
J
Lange
Céulne
C
Balkau
Beverley
B
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D015331:Cohort Studies; D064420:Drug-Related Side Effects and Adverse Reactions; D050171:Dyslipidemias / Q000188:drug therapy; D005260:Female; D005602:France; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012307:Risk Factors