Nickel-catalyzed allylic substitution of simple alkenes.
Nickel-catalyzed intermolecular allylic substitution of simple alkenes (ethylene and alpha olefins) is described. This method is the first catalytic intermolecular process for direct allylation of nonconjugated, nonstrained simple alkenes. Catalyst loadings as low as 2.5 mol % Ni afford the desired product in high yield in both gram-scale and smaller scale coupling reactions.
Matsubara
Ryosuke
R
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Jamison
Timothy F
TF
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D009532:Nickel / Q000737:chemistry*
D000475:Alkenes; D009532:Nickel