title: Incidence of meningitis secondary to suppurative otitis media in adults.
abstract: OBJECTIVE
  Meningitis is the commonest intracranial complication of suppurative otitis media, and carries the risk of death and life-changing morbidity. This study aimed to estimate the risk of an adult in the UK developing otogenic meningitis.
  
  
  METHODS
  Adults hospitalised with meningitis in Bristol from 1997 to 2002 were identified retrospectively. Cases confirmed by positive blood culture or cerebrospinal fluid investigation were studied. A case was classified as otogenic if there was coexistent evidence of ear infection.
  
  
  RESULTS
  Eighty-seven cases of meningitis were analysed. The overall mortality rate was 5.7 per cent. Acute and chronic suppurative otitis media accounted for 13 and three cases, respectively. The adult population of Bristol at the midpoint of the study was 635,976.
  
  
  CONCLUSIONS
  In this study, the age-adjusted incidence of otogenic meningitis was 0.42 per 100,000 per year.
authors.affiliation: Department of Otolaryngology, National University Hospital, Singapore.
authors.forename: S I
authors.initials: SI
authors.lastname: Ibrahim
authors.forename: P P
authors.initials: PP
authors.lastname: Cheang
authors.forename: D A
authors.initials: DA
authors.lastname: Nunez
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002908:Chronic Disease; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000150:complications*; D011320:Primary Health Care; D018570:Risk Assessment; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult