title: Management of bladder cancer with Studer orthotopic neobladder: 13-year experience.
abstract: BACKGROUND
  We present the results of patients submitted to a Studer type urinary orthotopic derivation after radical cystectomy.
  
  
  METHODS
  The files of patients with bladder cancer submitted to a radical cystectomy plus the procedure of the ileal neobladder were reviewed in our hospital from January 1992 until December 2004. Patients were divided into two groups: group A--60 years old or younger and group B-->60 years old.
  
  
  RESULTS
  From 306 patients submitted to radical cystectomy with urinary derivation, there were 42 patients (13.7%) included with Studer type neobladder. There were 34 (80.9 %) men and 8 (19.1%) women, with an average age of 60 years. Average surgical time was 7 h with an average blood loss of 1600 cc requiring transfer to intensive care unit (ICU) in 55% of the cases. The most frequent early complication was metabolic acidosis that was present in 28 (66%) patients. The most severe complication was ileal-ureter urinary leak, which was present in seven (16.6 %) patients. Among the most frequent late complications are the day- and night-time urinary incontinence often related to urinary infections and intestinal occlusion. Overall 5-year survival was 71%, cancer-specific mortality was 15% and surgical-related mortality was 7.3%.
  
  
  CONCLUSIONS
  The performance of procedures with orthotopic neobladders is actually feasible in experienced hospital centers and is a valuable alternative to urinary heterotopic derivation with ileal conduit. Postoperative patient management and regular follow-up is of major importance.
authors.affiliation: Servicio de Urología Oncológica, Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D F, Mexico. andres2424@yahoo.com
authors.forename: Andrés
authors.initials: A
authors.lastname: Martínez-Cornelio
authors.forename: Narciso
authors.initials: N
authors.lastname: Hernández-Toriz
authors.forename: Joel
authors.initials: J
authors.lastname: Quintero-Becerra
authors.forename: Donaciano
authors.initials: D
authors.lastname: Flores-López
authors.forename: Jorge
authors.initials: J
authors.lastname: Moreno-Palacios
authors.forename: Emanuel
authors.initials: E
authors.lastname: Vázquez-Martínez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015653:Cystectomy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D001743:Urinary Bladder / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D016476:Urinary Reservoirs, Continent