Nerve conduction changes following arteriovenous fistula construction in hemodialysis patients.
BACKGROUND
Peripheral neuropathy is a common complication of chronic renal failure (CRF). Superimposed neuropathies may complicate arteriovenous fistulas (AVF) construction. The aim of this study was to evaluate the effect of AVF construction on nerve conduction.


METHODS
Twenty-six patients were included in this prospective case-control study. All patients underwent clinical and electrophysiologic evaluations 1 week before and 3 months after AVF placement. A side-to-side fistula was set up for all patients, and the radial, ulnar, and median nerves were studied. Patient's non-fistula hand served as a control.


RESULTS
No significant changes were observed on neurological examination of the upper limbs following AVF construction. In the case of motor nerves, the AVF hand had decreased amplitude of distal and proximal segments of the radial nerve (P = 0.025 and P = 0.042), proximal segment of the median nerve (P = 0.025), and increased distal latency of the ulnar nerve (P = 0.027). No significant changes were observed for sensory parameters.


CONCLUSIONS
This study showed that all three nerves of the upper extremity can be affected by hemodialysis vascular access construction in patients with CRF, and the motor radial nerve was the most affected nerve.
Talebi
Mahnaz
M
Department of Neurology, Imam Reza Hospital, Tabriz University (Medical Sciences), Tabriz, Iran. talebineuro@yahoo.com
Salari
Behzad
B
Ghannadan
Hossein
H
Kakaei
Farzad
F
Azar
Sima Abedi
SA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D009460:Neurologic Examination; D011115:Polyneuropathies / Q000150:complications / Q000503:physiopathology*; D011446:Prospective Studies; D011826:Radial Nerve / Q000503:physiopathology; D006435:Renal Dialysis / Q000009:adverse effects*; D014459:Ulnar Nerve / Q000503:physiopathology; D055815:Young Adult