The testosterone two-step is really a minuet.
Newly developed genetic models indicate that estrogen receptors (ERs) alone mediate prenatal masculinization of the mouse brain to organize reproductive and territorial behaviors, while postnatal activation of androgen receptors (ARs) potentiates specific components of those behaviors. These results and others offer a model of how AR and ER pathways interact to fully masculinize the brain and behavior of male mice.
Hamson
Dwayne K
DK
Neuroscience Program and Department of Psychology, Michigan State University, East Lansing, MI 48824, USA.
Jordan
Cynthia L
CL
Breedlove
S Marc
SM