title: Evaluation of the Calhoun Vision UV Light Adjustable Lens implanted following cataract removal.
abstract: OBJECTIVE
  To evaluate the effectiveness of a silicone intraocular lens (IOL) that can be adjusted following implantation using ultraviolet (UV) irradiation.
  
  
  METHODS
  Prospective clinical trial of 40 patients (40 eyes) with visually significant cataract. Participants underwent small-incision phacoemulsification followed by implantation of a light-adjustable, silicone IOL (Light Adjustable Lens [LAL], Calhoun Vision). All patients were required to wear UV-protective eyewear at all times, until final lock-in. Pre- and postoperative clinical parameters included distance visual acuity and manifest refraction.
  
  
  RESULTS
  At average 2 weeks postoperative (range: 10 to 21 days), patients were seen and refracted to determine type and magnitude of refractive error needing correction. All patients required an initial adjustment of the LAL, whereas 28 required a second UV treatment and none required a third adjustment. At 4 months postoperative, mean refraction was 0.04±0.37 diopters (D) (range: -0.88 to 0.50 D), mean sphere was 0.24±0.40 D (range: -0.50 to 0.75 D), and mean cylinder was 0.41±0.25 D (range: 1.00 to 0.0 D). Eighty-one percent of eyes gained 2 or more lines of corrected distance visual acuity.
  
  
  CONCLUSIONS
  The adjustment and lock-in procedures were well tolerated by patients. The Calhoun Vision LAL is a promising technology with the potential to eliminate postoperative refractive surprises of up to 2.00 D of refractive and cylindrical error following implantation.
authors.affiliation: Center for Vision Science, Ruhr University Eye Hospital, In der Schornau 23-25, 44892 Bochum, Germany. fritz.hengerer@kk-bochum.de
authors.forename: Fritz H
authors.initials: FH
authors.lastname: Hengerer
authors.forename: Ina
authors.initials: I
authors.lastname: Conrad-Hengerer
authors.forename: Sabine E
authors.initials: SE
authors.lastname: Buchner
authors.forename: H Burkhard
authors.initials: HB
authors.lastname: Dick
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011379:Prognosis; D011446:Prospective Studies; D011474:Prosthesis Design; D012029:Refraction, Ocular / Q000502:physiology; D014466:Ultraviolet Rays; D014792:Visual Acuity / Q000502:physiology