[Current views on antioxidative activity of glutathione and glutathione-depending enzymes].
Reduced glutathione (GSH), gamma-glutamyl-L-cysteineglycine, is a tripeptide widespread in plants, animals, and man as a low-molecular weight SH-containing compound. This review presents results of published and original studies concerned with the synthesis and the role of glutathione and glutathione-dependent enzymes in antioxidative processes, such as maintenance and regulation of cell status, glutathionilation and deglutathionilation, redox-dependent signaling, and apoptosis.
Kalinina
E V
EV
Chernov
N N
NN
Aleud
R
R
Novichkova
M D
MD
Saprin
A N
AN
Berezov
T T
TT
D000818:Animals; D017209:Apoptosis; D054477:Glutaredoxins / Q000502:physiology*; D005978:Glutathione / Q000502:physiology*; D005979:Glutathione Peroxidase / Q000502:physiology*; D005982:Glutathione Transferase / Q000502:physiology*; D006801:Humans; D010084:Oxidation-Reduction; D015398:Signal Transduction
D054477:Glutaredoxins; D005979:Glutathione Peroxidase; D005982:Glutathione Transferase; D005978:Glutathione