title: Radiation therapy for gastric wall metastasis from esophageal carcinoma.
abstract: An 86-year-old man with dysphagia underwent gastrointestinal fiberscopy (GIF) and was found to have a circumferential type 3 advanced carcinoma in the upper thoracic esophagus and a type 2 tumor in the posterior wall of the gastric body. Microscopic examination of biopsy specimens of both tumors demonstrated moderately differentiated squamous cell carcinoma. He was diagnosed as having stage IVb (T3N0M1b) esophageal carcinoma with gastric wall metastasis. A total of 60 Gy in 30 fractions of three-dimensional conformal radiation therapy (3D-CRT) was first administered to the esophageal carcinoma, next to the gastric wall metastasis. Concurrent chemotherapy was not given because of the patient's refusal. No subjective morbidity was observed during the treatment. In the GIF study immediately after 3D-CRT, both esophageal and gastric wall tumors had attained a complete response. The dysphagia dissolved as the esophageal tumor shrunk. The patient has been doing well for 17 months after the start of 3D-CRT. No local recurrence was observed in either the esophagus or the stomach during follow-up GIF. Considering the dismal prognosis of esophageal carcinoma patients with intramural metastasis to the stomach, a watchful follow-up is needed.
authors.affiliation: Department of Radiology, Osaka Kouseinenkin Hospital, Fukushima-ku, Osaka, Japan, cuhsk805@occn.zaq.ne.jp
authors.forename: Naoko
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Jin
authors.initials: J
authors.lastname: Iwazawa
authors.forename: Hisashi
authors.initials: H
authors.lastname: Abe
authors.forename: Takashi
authors.initials: T
authors.lastname: Mitani
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Kagawa
mesh_terms: D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000556:secondary*; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal; D012004:Rectal Neoplasms / Q000601:surgery; D013274:Stomach Neoplasms / Q000532:radiotherapy* / Q000556:secondary*