An improved route to PUGNAc and its galacto-configured congener.
An efficient, scalable, and reliable synthesis of PUGNAc and its galacto-configured congener is reported.
Goddard-Borger
Ethan D
ED
Chemistry M313, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
Stubbs
Keith A
KA
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D005690:Galactose; D006031:Glycosylation; D008722:Methods; D010091:Oximes / Q000138:chemical synthesis*; D048448:Phenylcarbamates / Q000138:chemical synthesis*
D010091:Oximes; D048448:Phenylcarbamates; C068836:N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime; D000117:Acetylglucosamine; D005690:Galactose