title: Clostridium difficile toxinotype XI (A-B-) exhibits unique arrangement of PaLoc and its upstream region.
abstract: Clostridium difficile toxinotype XI strains do not produce toxins A (TcdA) or B (TcdB) but do possess a nonfunctional remnant of the pathogenicity locus (PaLoc), bearing part of the sequence for tcdA. This is the first report of a type with absent upstream terminal PaLoc sequences and major genetic rearrangements of the PaLoc region.
authors.affiliation: Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, Ljubljana, Slovenia. barbara.geric@guest.arnes.si
authors.forename: Barbara
authors.initials: B
authors.lastname: Geric Stare
authors.forename: Maja
authors.initials: M
authors.lastname: Rupnik
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics*; D016360:Clostridioides difficile / Q000235:genetics*; D004768:Enterotoxins / Q000235:genetics; D023061:Gene Order; D056426:Genetic Loci
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; C041348:tcdA protein, Clostridium difficile