title: [Endomyocardial disease as the first manifestation of hypereosinophilic syndrome].
abstract: A case of hypereosinophilic syndrome (HES) initially manifesting as endomyocardial disease in a 21-year-old man is presented. The diagnosis of HES was made according to the Chusid's criteria. Myeloproliferative disorders were excluded and corticosteroid therapy with prednisone at a dose of 1 mg/kg/d was started immediately. After 30 days of continuous corticotherapy the patient recovered completely. His blood eosinophil count decreased from 8740 cells/microL (48.7%) to 30 cells/microL (0.3%). Then, prednisone was discontinued gradually. During 18-month follow-up the patient was free from cardiovascular symptoms and his complete blood count was normal. We also present the current state of knowledge on the cardiovascular complications of hypereosinophilic syndrome.
authors.affiliation: Klinika Choroby Wiencowej, Instytut Kardiologii, Uniwersytet Jagiellonski, Krakow.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Poreba
authors.forename: Paweł
authors.initials: P
authors.lastname: Rostoff
authors.forename: Ewa
authors.initials: E
authors.lastname: Konduracka
authors.forename: Patrycja
authors.initials: P
authors.lastname: Pikul
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Rucińska
authors.forename: Mieczysław
authors.initials: M
authors.lastname: Pasowicz
authors.forename: Wiesława
authors.initials: W
authors.lastname: Piwowarska
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004719:Endomyocardial Fibrosis / Q000150:complications / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009206:Myocardium / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D011241:Prednisone