title: [Randomized controlled trial on manipulation for the treatment of cervical vertigo of high flow velocity type].
abstract: OBJECTIVE
  To explore the effects of manipulation and traction combined with Nimodipine on the blood flow velocity of vertebrobasilar artery (VBA) in cervical vertigo of high flow velocity,and to evaluate clinical therapeutic effects between two methods.
  
  
  METHODS
  From March 2008 to Feburary 2009,70 patients who were diagnosed as high flow velocity of cervical vertigo were randomly divided into treatment group (35 cases) and control group (35 cases). Among 70 patients, 32 were male and 38 were female. The age ranged from 21 to 45 years with an average of 37.6 years. The disease course ranged from one day to two years with an average of 12.6 days. Patients of the treatment group were treated with manipulation for total three weeks, three times once week. The patients in the control group were treated with traction (weight ranged from 5 to 6 kg, 20 minutes each time, once every other day) and Nimodipine for total three weeks (three times each day, and with a dose of 40 mg each time). After three weeks, the changes of flow velacity of VBI and score before and after treatment were observed using transcranil Doppler (TCD) and Evaluation Scale for Cervical Vertigo. After six weeks, the therapeutic effects were assessed.
  
  
  RESULTS
  The mean velocity in left vertebral artery (LVA), right vertebral artery (RVA) and basilar artery (BA) were obviously lower than those before treatment in two groups (P < 0.01). The LVA, RVA and BA of the treatment group was lower than those of control group after 3 weeks (P < 0.01). There was significant difference in vertigo score after treatment between the two groups. The improvement rate of double-sides sign in X-ray image and the therapeutic effects of treatment group was superior to that of control group (P < 0.01).
  
  
  CONCLUSIONS
  The effect of manipulation on flow velocity of VBA is superior to that of traction combined with Nimodipine, and there are better therapeutic effects in treating cervical vertigo of high flow velocity in comparison with traction combined with Nimodipine. But there are more higher demands for manipulation's application.
authors.affiliation: The First Affiliated Hospital of Zhejiang University of TCM, Hangzhou 310006, Zhejiang, China. duhgxy@yahoo.com
authors.forename: Hong-Gen
authors.initials: HG
authors.lastname: Du
authors.forename: Hui
authors.initials: H
authors.lastname: Wei
authors.forename: Mei-Zhen
authors.initials: MZ
authors.lastname: Huang
authors.forename: Zhong
authors.initials: Z
authors.lastname: Jiang
authors.forename: Shu-Liang
authors.initials: SL
authors.lastname: Ye
authors.forename: Hong-Quan
authors.initials: HQ
authors.lastname: Song
authors.forename: Ji-Wei
authors.initials: JW
authors.lastname: Yu
authors.forename: Xi-Tao
authors.initials: XT
authors.lastname: Ning
mesh_terms: D000328:Adult; D001158:Arteries / Q000503:physiopathology*; D001783:Blood Flow Velocity; D002574:Cervical Vertebrae / Q000098:blood supply*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D026201:Musculoskeletal Manipulations; D014717:Vertigo / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult