[Central obesity index and cardiovascular risk factors in polycystic ovary syndrome].
BACKGROUND
Women with polycystic ovary syndrome (PCOS) present a high prevalence of abdominal obesity, which is associated with an increased cardiovascular risk.


OBJECTIVE
To verify the accuracy of the waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and the conicity index (CI) in the detection of cardiovascular risk factors (CVRF) in women with PCOS.


METHODS
The present transversal study allocated 102 women (26.5 +/- 5 years) with a diagnosis of PCOS, according to the Rotterdam criteria. Total cholesterol (TC), triglycerides (TG), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), fasting glucose, glucose after the oral glucose tolerance test (OGTT) and blood pressure (BP) were evaluated in all patients, in addition to the anthropometric variables.


RESULTS
The WHtR was the marker that presented significant positive correlations with the highest number of CVRF (BP, TG and post-OGTT glucose), whereas there was a negative correlation with HDL-C. All the evaluated anthropometric markers were positively correlated with BP, whereas WC and WHR also presented a positive correlation with TG. Regarding the accuracy for the detection of CVRF, the anthropometric markers presented a sensibility > 60%, especially the WHtR, which had a sensibility > 70%.


CONCLUSIONS
The WHtR showed to be the most accurate anthropometric indicator for the prediction of CVRF. In this sense, we propose the inclusion of this easily-measured parameter in the clinical assessment for the screening of women with PCOS and CVRF.
Costa
Eduardo Caldas
EC
Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.
Soares
Elvira Maria Mafaldo
EM
Lemos
Telma Maria Araujo Moura
TM
Maranhão
Técia Maria de Oliveira
TM
Azevedo
George Dantas
GD
D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D056128:Obesity, Abdominal / Q000175:diagnosis*; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011237:Predictive Value of Tests; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio / Q000379:methods / Q000592:standards*; D055815:Young Adult
D008055:Lipids; D014280:Triglycerides