Psoriasis and body mass index.
Recently, it has emerged a strong association between increased adiposity, obesity, and psoriasis. Body Mass Index (BMI) is a simple index of weight-for-height that is commonly used to classify underweight, overweight and obesity in adults. Psoriasis has also been associated with systemic obesity-related disorders including type 2 diabetes, hypertension, ischemic heart disease, and combined hyperlipidemia, as a part of metabolic syndrome. Not only the obesity may be associated with higher psoriasis incidence and activity, and prevalence of obesity-related syndromes, but it may also influence the therapeutic approach to disease and the clinical response to systemic treatment. Consequently, the approach of the experienced dermatologist will take into account all the aspects of the patient clinical conditions including the analysis of BMI for the choice of the best suitable therapy.
Hercogová
Jana
J
Department of Dermatological Sciences, University of Florence, Florence, Italy.
Ricceri
Frederica
F
Tripo
Lara
L
Lotti
Torello
T
Prignano
Francesca
F
D050154:Adiposity / Q000187:drug effects / Q000502:physiology; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology; D000068800:Etanercept; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D007074:Immunoglobulin G / Q000627:therapeutic use; D007249:Inflammation / Q000150:complications / Q000453:epidemiology; D000069285:Infliximab; D008297:Male; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab; D000068800:Etanercept