title: Estimating continuous 4D wall motion of cerebral aneurysms from 3D rotational angiography.
abstract: This paper presents a technique to recover dynamic 3D vascular morphology from a single 3D rotational X-ray angiography acquisition. The dynamic morphology corresponding to a canonical cardiac cycle is represented via a 4D B-spline based spatiotemporal deformation. Such deformation is estimated by simultaneously matching the forward projections of a sequence of the temporally deformed 3D reference volume to the entire 2D measured projection sequence. A joint use of two acceleration strategies is also proposed: semi-precomputation of forward projections and registration metric computation based on a narrow-band region-of-interest. Digital and physical phantoms of pulsating cerebral aneurysms have been used for evaluation. Accurate estimation has been obtained in recovering sub-voxel pulsation, even from images with substantial intensity inhomogeneity. Results also demonstrate that the acceleration strategies can reduce memory consumption and computational time without degrading the performance.
authors.affiliation: Center for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra, Barcelona, Spain.
authors.forename: Chong
authors.initials: C
authors.lastname: Zhang
authors.forename: Mathieu
authors.initials: M
authors.lastname: De Craene
authors.forename: Maria-Cruz
authors.initials: MC
authors.lastname: Villa-Uriol
authors.forename: Jose M
authors.initials: JM
authors.lastname: Pozo
authors.forename: Bart H
authors.initials: BH
authors.lastname: Bijnens
authors.forename: Alejandro F
authors.initials: AF
authors.lastname: Frangi
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D002533:Cerebral Angiography / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D009068:Movement; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012399:Rotation; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*