Ellagitannins from Geranium potentillaefolium and G. bellum.
The aerial parts of Geranium potentillaefoium afforded geraniin (1), corilagin (2), gallic acid (4), methyl gallate (6), methyl brevifolincarboxylate (7), quercetin, quercetin 3-O-beta-D-glucopyranoside, quercetin 3-O-beta-D-[6"-O-galloyl)glucopyranoside, kaempferol, beta-sitosterol 3-O-beta-D-glucopyranoside and beta-sitosterol, while the aerial parts of G. bellum gave the same compounds in addition to kaempferol 3-O-beta-D-glucopyranoside, isolated instead of kaempferol. The substances were identified by 1D and 2D NMR spectroscopy in comparison with published data. The water decoction preparations from air-dried plant materials (2.5 g) contain ca. 4.6 % of the ellagitannin 1, envisaging that when such decoction is ingested (250 mL), a therapeutic dose of ca. 36 mg of the antitumor ellagic acid (3) may be incorporated into the organism.
Gayosso-De-Lucio
Juan A
JA
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Hidalgo, Hidalgo, México.
Torres-Valencia
J Martín
JM
Cerda-García-Rojas
Carlos M
CM
Joseph-Nathan
Pedro
P
D031315:Geranium / Q000737:chemistry*; D047348:Hydrolyzable Tannins / Q000737:chemistry / Q000302:isolation & purification*; D019906:Nuclear Magnetic Resonance, Biomolecular; D035261:Plant Components, Aerial / Q000737:chemistry
D047348:Hydrolyzable Tannins