title: [Current views on antioxidative activity of glutathione and glutathione-depending enzymes].
abstract: Reduced glutathione (GSH), gamma-glutamyl-L-cysteineglycine, is a tripeptide widespread in plants, animals, and man as a low-molecular weight SH-containing compound. This review presents results of published and original studies concerned with the synthesis and the role of glutathione and glutathione-dependent enzymes in antioxidative processes, such as maintenance and regulation of cell status, glutathionilation and deglutathionilation, redox-dependent signaling, and apoptosis.
authors.forename: E V
authors.initials: EV
authors.lastname: Kalinina
authors.forename: N N
authors.initials: NN
authors.lastname: Chernov
authors.forename: R
authors.initials: R
authors.lastname: Aleud
authors.forename: M D
authors.initials: MD
authors.lastname: Novichkova
authors.forename: A N
authors.initials: AN
authors.lastname: Saprin
authors.forename: T T
authors.initials: TT
authors.lastname: Berezov
mesh_terms: D000818:Animals; D017209:Apoptosis; D054477:Glutaredoxins / Q000502:physiology*; D005978:Glutathione / Q000502:physiology*; D005979:Glutathione Peroxidase / Q000502:physiology*; D005982:Glutathione Transferase / Q000502:physiology*; D006801:Humans; D010084:Oxidation-Reduction; D015398:Signal Transduction
chemical_list: D054477:Glutaredoxins; D005979:Glutathione Peroxidase; D005982:Glutathione Transferase; D005978:Glutathione