On-resin dimerization incorporates a diverse array of pi-conjugated functionality within aqueous self-assembling peptide backbones.
We report a convenient method to incorporate pi-electron units into peptides that assemble into amyloid-like supramolecular polymers, discussing the scope of the process and preliminary characterization of the resulting nanomaterials. Self-assembly manipulates these "electronic peptides" into delocalized sub-10 nm 1-D nanostructures under completely aqueous conditions.
Vadehra
Geeta S
GS
Department of Chemistry, Johns Hopkins University, 3400 N. Charles St. (NCB 316), Baltimore, MD 21218, USA.
Wall
Brian D
BD
Diegelmann
Stephen R
SR
Tovar
John D
JD
D019281:Dimerization; D004583:Electrons; D006863:Hydrogen-Ion Concentration; D055767:Immobilized Proteins / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D014867:Water / Q000737:chemistry
D055767:Immobilized Proteins; D010455:Peptides; D014867:Water