title: Finite element analysis of the human mandible at 3 different stages of life.
abstract: OBJECTIVE
  This study analyzed detailed models of human mandibles at 3 different stages of life with simulation of supra normal chewing forces at static conditions.
  
  
  METHODS
  Finite element analysis (FEA) was used to generate models from cone-beam computerized tomograms (CBCT) of 3 patients aged 12, 20, and 67 years, using numerically calculated material parameters. Estimated chewing forces were then applied to the simulations.
  
  
  RESULTS
  The results reflect higher elasticity in younger models in all regions of the mandible. The experimental models show that physiologic load stress and strain distributional changes of the mandible vary according to age.
  
  
  CONCLUSIONS
  The CBCT-based model generation used in this study provided high-quality model definition of the 3 individual patients of different ages. FEA has great potential to predict bone responses to paradigms of mechanical activity. Future applications of FEA will include surgical planning, surgical hardware testing, and the design of scaffolds and tissue-engineered constructs.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Dentistry, Faculty of Dentistry, Semmelweis University, Budapest, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Bujtár
authors.forename: George K B
authors.initials: GK
authors.lastname: Sándor
authors.forename: Attila
authors.initials: A
authors.lastname: Bojtos
authors.forename: Attila
authors.initials: A
authors.lastname: Szucs
authors.forename: József
authors.initials: J
authors.lastname: Barabás
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D001732:Bite Force; D002648:Child; D003198:Computer Simulation; D054893:Cone-Beam Computed Tomography; D003799:Dental Stress Analysis / Q000379:methods*; D004548:Elasticity; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D007575:Jaw, Edentulous; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000254:growth & development / Q000502:physiology*; D008409:Mastication / Q000502:physiology*; D008953:Models, Anatomic; D055815:Young Adult