In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth.
A method is proposed to measure transverse blood flow by using photoacoustic Doppler broadening of bandwidth. By measuring bovine blood flowing through a plastic tube, the linear dependence of the broadening on the flow speed was validated. The blood flow of the microvasculature in a mouse ear and a chicken embryo (stage 16) was also studied.
Yao
Junjie
J
Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, USA.
Maslov
Konstantin I
KI
Shi
Yunfei
Y
Taber
Larry A
LA
Wang
Lihong V
LV
D000818:Animals; D001783:Blood Flow Velocity; D002417:Cattle / Q000097:blood; D002642:Chick Embryo / Q000098:blood supply; D004423:Ear / Q000098:blood supply; D018056:Hemorheology; D051379:Mice; D008815:Mice, Inbred Strains; D055095:Optics and Photonics / Q000379:methods*; D012039:Regional Blood Flow; D012212:Rheology / Q000379:methods*; D018608:Ultrasonography, Doppler