title: Compositions and in vitro anticancer activities of the leaf and fruit oils of Litsea cubeba from Taiwan.
abstract: The leaf and fruit essential oils of Litsea cubeba, extracted by hydrodistillation, were assessed for anticancer activities. A total of 53 and 50 compounds were identified, respectively from the leaf and fruit oils, and their yields were 13.9 +/- 0.09% and 4.0 +/- 0.03%, v/w, of the oven-dried materials, respectively. The main compound in the leaf oil was 1,8-cineol, and in the fruit oil, citral. The fruit oil, but not that of the leaf, exhibited cytotoxic activity against human lung, liver and oral cancer cells.
authors.affiliation: Division of Wood Cellulose, Taiwan Forestry Research Institute,Taipei, Taiwan.
authors.forename: Chen-Lung
authors.initials: CL
authors.lastname: Ho
authors.forename: Ou
authors.initials: O
authors.lastname: Jie-Pinge
authors.forename: Yao-Chi
authors.initials: YC
authors.lastname: Liu
authors.forename: Chien-Ping
authors.initials: CP
authors.lastname: Hung
authors.forename: Ming-Chih
authors.initials: MC
authors.lastname: Tsai
authors.forename: Pei-Chun
authors.initials: PC
authors.lastname: Liao
authors.forename: Eugene I-Chen
authors.initials: EI
authors.lastname: Wang
authors.forename: Yi-Lin
authors.initials: YL
authors.lastname: Chen
authors.forename: Yu-Chang
authors.initials: YC
authors.lastname: Su
mesh_terms: D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D032862:Litsea / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D013624:Taiwan; D013729:Terpenes / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D010938:Plant Oils; D013729:Terpenes