Synthesis and hypolipidemic activity of novel 2-(4-(2-substituted aminothiazole-4-yl) phenoxy) acetic acid derivatives.
A novel series of aminotihazole compounds possessing phenoxy acetic acid moiety were synthesized. The synthesized compounds were evaluated for their hypolipidemic activity by using high fat diet induced hyperlipidemia in Sprague-Dawley rats.
Mokale
Santosh N
SN
Y. B. Chavan College of Pharmacy, Aurangabad (MS), India.
Sanap
Priyanka T
PT
Shinde
Devanand B
DB
D000085:Acetates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005260:Female; D000960:Hypolipidemic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D013329:Structure-Activity Relationship
D000085:Acetates; D000960:Hypolipidemic Agents