title: Field-amplified sample injection-micellar electrokinetic capillary chromatography for the analysis of bisphenol A, bisphenol F, and their diglycidyl ethers and derivatives in canned soft drinks.
abstract: Conditions were established for the separation and analysis of bisphenol A, bisphenol F, and their diglycidyl ethers by micellar electrokinetic capillary chromatography (MECC). Good resolution was obtained for all compounds, although in order to achieve the separation of ortho-ortho, ortho-para, and para-para isomers of bisphenol F diglycidyl ether (BFDGE), BFDGE x 2H(2)O and BFDGE x 2HCl, it was necessary to use a 25 microm id fused silica capillary. To increase sensitivity, a field-amplified sample injection (FASI)-MECC method was developed using 10 mM SDS solution as injection matrix and a 75 microm id fused silica capillary. Instrumental quality parameters such as LODs (<55 microg/L with standards), linearity (r(2)>0.999), and run-to-run and day-to-day precisions (RSD values lower than 12.5%) were determined. Finally, the suitability of the FASI-MECC method for the analysis of bisphenol A, bisphenol F, and their diglycidyl ethers in canned soft drinks was evaluated. Quantitation was performed by matrix-matched calibration using a plastic-bottled isotonic drink as matrix. The results showed that FASI-MECC is an economic method for the screening and quantitation of these kinds of compounds in soft drink beverages, with no loss of reproducibility, and effective at concentrations lower than the specific migration level values established by the European Union.
authors.affiliation: Department of Analytical Chemistry, University of Barcelona, Barcelona, Spain.
authors.forename: Héctor
authors.initials: H
authors.lastname: Gallart-Ayala
authors.forename: Oscar
authors.initials: O
authors.lastname: Núñez
authors.forename: Encarnación
authors.initials: E
authors.lastname: Moyano
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Galceran
mesh_terms: D001559:Benzhydryl Compounds; D002138:Calibration; D002253:Carbonated Beverages / Q000032:analysis* / Q000592:standards; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D004852:Epoxy Compounds / Q000032:analysis* / Q000737:chemistry; D005504:Food Analysis / Q000379:methods*; D018857:Food Packaging; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004852:Epoxy Compounds; D010636:Phenols; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds; C006780:bisphenol A; C423722:bisphenol F diglycidyl ether