title: Young age and termination of pregnancy during the second trimester are risk factors for repeat second-trimester abortion.
abstract: OBJECTIVE
  The objective of the study was to characterize women undergoing a termination of pregnancy (TOP) during the second trimester and to evaluate the risk factors and timing of repeat TOP.
  
  
  METHODS
  This nationwide retrospective cohort study investigated 41,750 women who underwent TOP during the first (n = 39,850) or second (n = 1900) trimester in Finland in 2000-2005. The follow-up time was until repeat TOP or until Dec. 31, 2006.
  
  
  RESULTS
  TOP during the second trimester increases the risk of repeat TOP (hazard ratio [HR], 1.4; 95% confidence interval [CI], 1.3-1.6), repeat second-trimester TOP (HR, 3.8; 95% CI, 2.9-5.1), and repeat TOP after 16 weeks of gestation (HR, 5.0; 95% CI, 3.3-7.7). The other risk factor for these is young age (HR, 7.0, 95% CI, 5.3-9.3; and HR, 12.5; 95% CI, 3.1-50.4 for age <20 years).
  
  
  CONCLUSIONS
  Second-trimester TOP and young age are risk factors for repeat second-trimester TOP. Special focus on these women might be effective in decreasing repeat abortions.
authors.affiliation: Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: Maarit J
authors.initials: MJ
authors.lastname: Mentula
authors.forename: Maarit
authors.initials: M
authors.lastname: Niinimäki
authors.forename: Satu
authors.initials: S
authors.lastname: Suhonen
authors.forename: Elina
authors.initials: E
authors.lastname: Hemminki
authors.forename: Mika
authors.initials: M
authors.lastname: Gissler
authors.forename: Oskari
authors.initials: O
authors.lastname: Heikinheimo
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data*; D000022:Abortion, Spontaneous / Q000453:epidemiology* / Q000209:etiology; D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008423:Maternal Age; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011336:Probability; D016016:Proportional Hazards Models; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D055815:Young Adult