[Effects of the blood glucose-adjusting recipe on blood glucose and pancreas islet pathology in diabetic mice].
OBJECTIVE
To study the effects of a self-formulated blood glucose-adjusting recipe on blood glucose and pathology of the pancreas in diabetic mice.


METHODS
Diabetes mellitus (DM) was induced in mice by injection of alloxan through the caudal vein. The blood glucose-adjusting recipe was administered in the mice at the doses of 20, 10 and 5 g/kg for 21 days, after which blood glucose was determined and the sugar tolerance was evaluated, and the pancreas and islet pathologies were examined microscopically.


RESULTS
The blood glucose-adjusting recipe at 20 g/kg significantly lowered the fast blood glucose in the mice, and at 20 and 10 g/kg, the recipe significantly lowered the blood glucose 2 h after glucose administration and increased the sugar tolerance. The pathological damage in the diabetic mice was alleviated after treatment with the recipe.


CONCLUSIONS
The blood glucose-adjusting recipe has a good effect in stabilizing blood glucose in mice.
Luo
Su-fang
SF
Institute of Healthy Food, Southern Medical University, Ghuangzhou 510515, China.
Chen
Yu-yao
YY
D000818:Animals; D001786:Blood Glucose / Q000187:drug effects*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D007515:Islets of Langerhans / Q000473:pathology*; D051379:Mice; D008517:Phytotherapy
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal