title: The effects of tautomerism on the nature of molecules in the solid state.
abstract: Tautomerism is a phenomenon well know to most chemists but frequently forgotten when chemistry leaves the bench and enters the computational realm. Through the examination of several examples from the crystallographic literature it can be clearly demonstrated that the tautomeric state of a molecules can strongly affect its nature.
authors.affiliation: Structural Chemistry, Global Pharmaceutical R & D, Abbott Laboratories, 100 Abbott Park Rd., Abbott Park, IL, 60064, USA. rodger.henry@abbott.com
authors.forename: Rodger F
authors.initials: RF
authors.lastname: Henry
mesh_terms: D003461:Crystallography; D007536:Isomerism; D008958:Models, Molecular; D011725:Pyridines / Q000737:chemistry*; D011728:Pyridones; D013449:Sulfonamides / Q000737:chemistry*
chemical_list: D011725:Pyridines; D011728:Pyridones; D013449:Sulfonamides; C534143:4-pyridone