title: [Glomerular deposition disease, regarding a case of fibrillary glomerulonephritis].
abstract: In routine diagnosis for renal biopsy, glomerular diseases are encountered that, viewed by electron microscopy, reveal deposits with a fibrillary structure in the extracellular matrix of the glomeruli. Amyloidosis is the most common glomerulopathy that shows deposits with an ultrastructural fibrillary structure. However, other glomerulopathies have deposits with an ultrastructural fibrillary structure and which are negative for Congo-red stain, but positive for immunoglobulins. Fibrillary glomerulonephritis is a well-characterized disease, and clearly identified in approximately 0.5% to 1% of biopsies of native kidneys. These cases usually manifest themselves as severe renal insufficiencies with nephrotic-range proteinuria. No treatment regimes have been clearly established and the prognosis is poor. Herein, the clinical and histological characteristics are described for the first case of idiopathic fibrillary glomerulonephritis reported in Colombia.
authors.affiliation: Servicio de Nefrología y Diálisis, Hospital El Tunal, E.S.E, Bogotá, D.C., Colombia. md_cantillo@yahoo.com
authors.forename: Jorge de Jesús
authors.initials: Jde J
authors.lastname: Cantillo
authors.forename: Rocío del Pilar
authors.initials: Rdel P
authors.lastname: López
authors.forename: Rafael Enrique
authors.initials: RE
authors.lastname: Andrade
mesh_terms: D003105:Colombia / Q000453:epidemiology; D003131:Combined Modality Therapy; D005920:Glomerular Mesangium / Q000737:chemistry / Q000648:ultrastructure; D005921:Glomerulonephritis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D009404:Nephrotic Syndrome / Q000209:etiology; D009765:Obesity / Q000150:complications; D010530:Peritoneal Dialysis
chemical_list: D007166:Immunosuppressive Agents