title: Comparing biomimetic and biological receptors for insulin sensing.
abstract: Biological information such as recognition abilities of antibodies can be transferred to man-made systems by imprinting. For instance, sensor layers with insulin-selective cavities yield similar selectivity and sensitivity as IgG. True "artificial antibodies" are achieved by synthesizing "polymer copies" retaining the original binding properties of anti-insulin IgG via two-step imprinting.
authors.affiliation: University of Vienna, Department of Analytical Chemistry, Währingerstrasse 38, 1090 Vienna, Austria.
authors.forename: Romana
authors.initials: R
authors.lastname: Schirhagl
authors.forename: Dagmar
authors.initials: D
authors.lastname: Podlipna
authors.forename: Peter A
authors.initials: PA
authors.lastname: Lieberzeit
authors.forename: Franz L
authors.initials: FL
authors.lastname: Dickert
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry* / Q000378:metabolism; D032701:Biomimetics / Q000379:methods*; D015374:Biosensing Techniques / Q000379:methods*; D006801:Humans; D007328:Insulin / Q000032:analysis* / Q000378:metabolism; D012680:Sensitivity and Specificity
chemical_list: D007328:Insulin