title: Lysidicins F-H, three new phloroglucinols from Lysidice rhodostegia.
abstract: Three new phloroglucinols, named lysidicins F-H (1-3), were isolated from the roots of Lysidice rhodostegia. These compounds have a unprecedented benzyl benzo[b]furo[3,2-d]furan skeleton, and lysidicin F (1) is the first example of natural product with trans-fused furan rings. Their structures were established on the basis of extensive spectroscopic analysis, and the absolute configurations of them were determined by computational methods. A possible biosynthetic pathway for 1-3 was also postulated.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College (Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education), Beijing 100050, PR China.
authors.forename: Xian-Fu
authors.initials: XF
authors.lastname: Wu
authors.forename: You-Cai
authors.initials: YC
authors.lastname: Hu
authors.forename: Shi-Shan
authors.initials: SS
authors.lastname: Yu
authors.forename: Nan
authors.initials: N
authors.lastname: Jiang
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.forename: Ren-Xiang
authors.initials: RX
authors.lastname: Tan
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Hai-Ning
authors.initials: HN
authors.lastname: Lv
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Shuang-Gang
authors.initials: SG
authors.lastname: Ma
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D003198:Computer Simulation; D007887:Fabaceae / Q000737:chemistry*; D008956:Models, Chemical; D008968:Molecular Conformation; D010696:Phloroglucinol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000975:Antioxidants; C551379:lysidicin F; C551380:lysidicin G; C551381:lysidicin H; D010696:Phloroglucinol