title: A novel glycoside from Acanthus hirsutus (Acanthaceae).
abstract: A novel glycoside, hirsutusoide (1), characterized as 2-(o-hydroxyphenyl)-2-hydroxyethenyl-O-beta-glucopyranoside, was isolated from the endemic Acanthus hirsutus Boiss. In addition to compound 1, three known glycosides, luteolin-7-O-beta-D-glucuronide (2), beta-sitosterol-3-O-beta-D-glucopyranoside (3) and (2R)-2-O-beta-D-glucopyranosyl-2H-1,4-benzoxazin-3(4H)-one (4), were also isolated. Compound 2 was the first report from this genus. Antimicrobial and antioxidant activity of the extracts and the novel compound were investigated by determining MIC (microg/mL) and IC50 (microg/mL) values, respectively.
authors.affiliation: Chemistry Department, Faculty of Science, Ege University, Bornova, Izmir, Turkey.
authors.forename: Seval
authors.initials: S
authors.lastname: Capanlar
authors.forename: Nazli
authors.initials: N
authors.lastname: Böke
authors.forename: Ihsan
authors.initials: I
authors.lastname: Yaşa
authors.forename: Süheyla
authors.initials: S
authors.lastname: Kirmizigül
mesh_terms: D027901:Acanthaceae / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D008826:Microbial Sensitivity Tests; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D016166:Free Radical Scavengers; D006027:Glycosides; D010636:Phenols; D013481:Superoxides