[Effect of alcohol concentration in water extraction and alcohol precipitation on preparation of effervescent tablets of Banlangen].
OBJECTIVE
To study effect of alcohol concentration in water extraction and alcohol precipitation on the preparation of effervescent tablets of Banlangen.


METHODS
Effects of different concentrations of alcohol precipitation on the Banlangen extract rate, metastasis rate of index components, extract properties of powder, preparation process were investigated, respectively.


RESULTS
Alcohol concentration on the Banlangen extract rate, metastasis rate of adenosine, extract the amount of saturated moisture, effervescent disintegration time of no significant impact, but spray drying process, dry granulation process.


CONCLUSIONS
Alcohol concentration has a significant effect on the preparation of effervescent tablets of Banlangen in the process of water extraction and alcohol precipitation, It suggest that the choice of concentration of alcohol precipitation should be based on experimental purposes, the entire preparation process of the system test results.
He
Yan
Y
National Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China. heyan95@yahoo.com.cn
Xin
Hongliang
H
Huang
Kai
K
Zhang
Yao
Y
Luo
Xiaojian
X
D011232:Chemical Precipitation; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry*; D013607:Tablets / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014867:Water / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D013607:Tablets; D014867:Water; D000431:Ethanol; C540579:banlangen