Synchronized changes in serum vascular endothelial growth factor during the clinical course of chronic systemic capillary leak syndrome.
Systemic capillary leak syndrome (SCLS) is a rare disease characterized by leakage of plasma from blood vessels into the interstitial space due to increased capillary permeability. We describe a 24-year-old man who was hospitalized with systemic edema, hypoalbuminemia, and disseminated intravascular coagulation. After extensive investigative procedures, he was diagnosed with chronic SCLS and made a gradual recovery after starting on prednisolone, terbutaline, and theophylline. We measured the patient's serum vascular endothelial growth factor (VEGF) over time and found a relationship between serum VEGF and the clinical course.
Kinoshita
Yoshiaki
Y
Advanced Medical Emergency and Critical Care Center, Yamaguchi University Hospital, Ube. yoshi-kino@umin.ac.jp
Kasaoka
Shunji
S
Fujita
Motoki
M
Oshima
Chiyomi
C
Kawamura
Yoshikatsu
Y
Tsuruta
Ryosuke
R
Maekawa
Tsuyoshi
T
D015415:Biomarkers / Q000097:blood; D019559:Capillary Leak Syndrome / Q000097:blood* / Q000175:diagnosis*; D002908:Chronic Disease; D006801:Humans; D008297:Male; D013997:Time Factors; D042442:Vascular Endothelial Growth Factors / Q000097:blood*; D055815:Young Adult
D015415:Biomarkers; D042442:Vascular Endothelial Growth Factors