Clinical effectiveness of transcervical polyp resection in women with endometrial polyps: randomized controlled trial.
OBJECTIVE
To estimate the clinical effectiveness of transcervical resection of endometrial polyps.


METHODS
Randomized controlled trial (Canadian Task Force classification I).


METHODS
University teaching hospital.


METHODS
One hundred fifty premenopausal women with endometrial polyps.


METHODS
Either transcervical resection of the polyp or observation for 6 months.


RESULTS
There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat.


CONCLUSIONS
Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.
Lieng
Marit
M
Department of Gynecology and Obstetrics, Oslo University Hospital Ullevål, Oslo, Norway. m.lieng@online.no
Istre
Olav
O
Sandvik
Leiv
L
Engh
Vibeke
V
Qvigstad
Erik
E
D000328:Adult; D016063:Blood Loss, Surgical; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods*; D008875:Middle Aged; D017060:Patient Satisfaction; D018579:Patient Selection; D011127:Polyps / Q000601:surgery*; D016896:Treatment Outcome; D014591:Uterine Diseases / Q000601:surgery*