title: Epitheloid hemangioendothelioma in patient with liver transplantation.
abstract: Malignant hepatic epithelioid hemangioendothelioma (HEH) is a rare malignant tumor of vascular origin with unknown aetiology and a variable natural course. At the time of diagnosis, most patients present with multifocal tumours lesions that involve both liver lobes. From the therapeutic aspect, liver resection (LRx), liver transplantation (LTx), chemotherapy, radiotherapy, and/or immunotherapy have been used in the treatment of patients with HEH. However, because of the rarity of this tumor and its unpredictable natural history, it is impossible to assess the effectiveness of these respective therapies. In this report, our objective was to present clinical aspects, diagnostic options, therapeutic modalities, and the clinical outcome of single patient with LTx because of this rare tumor.
authors.affiliation: Department of Medicine, University Hospital "Merkur", Zagreb, Croatia. tajana_filipec@yahoo.com
authors.forename: Tajana Filipec
authors.initials: TF
authors.lastname: Kanizaj
authors.forename: Vesna Colić
authors.initials: VC
authors.lastname: Cvrlje
authors.forename: Anna
authors.initials: A
authors.lastname: Mrzljak
authors.forename: Ika
authors.initials: I
authors.lastname: Kardum-Skelin
authors.forename: Dunja
authors.initials: D
authors.lastname: Sustercić
authors.forename: Dinko
authors.initials: D
authors.lastname: Segro
authors.forename: Denis
authors.initials: D
authors.lastname: Gustin
authors.forename: Branislav
authors.initials: B
authors.lastname: Kocman
mesh_terms: D018952:Antigens, CD34 / Q000378:metabolism; D044963:Biopsy, Fine-Needle; D004801:Eosine Yellowish-(YS); D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D016031:Liver Transplantation; D008751:Methylene Blue; D008875:Middle Aged; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; C043260:May-Grunwald Giemsa; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D008751:Methylene Blue; D004801:Eosine Yellowish-(YS)