Compositions and in vitro anticancer activities of the leaf and fruit oils of Litsea cubeba from Taiwan.
The leaf and fruit essential oils of Litsea cubeba, extracted by hydrodistillation, were assessed for anticancer activities. A total of 53 and 50 compounds were identified, respectively from the leaf and fruit oils, and their yields were 13.9 +/- 0.09% and 4.0 +/- 0.03%, v/w, of the oven-dried materials, respectively. The main compound in the leaf oil was 1,8-cineol, and in the fruit oil, citral. The fruit oil, but not that of the leaf, exhibited cytotoxic activity against human lung, liver and oral cancer cells.
Ho
Chen-Lung
CL
Division of Wood Cellulose, Taiwan Forestry Research Institute,Taipei, Taiwan.
Jie-Pinge
Ou
O
Liu
Yao-Chi
YC
Hung
Chien-Ping
CP
Tsai
Ming-Chih
MC
Liao
Pei-Chun
PC
Wang
Eugene I-Chen
EI
Chen
Yi-Lin
YL
Su
Yu-Chang
YC
D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D032862:Litsea / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D013624:Taiwan; D013729:Terpenes / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification
D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D010938:Plant Oils; D013729:Terpenes