[Prevention of early-onset neonatal group B streptococcal infection: neonatal outcome after introduction of national screening guideline].
OBJECTIVE
To evaluate the effectiveness of introduction of national guideline to prevent early-onset group B streptococcal (EOGBS) disease, number of screened women and incidence of GBS colonization.


METHODS
Retrospective cohort study.


METHODS
Department of Obstetrics and Gynaecology, Department of Neonatology, University Hospital Ostrava.


METHODS
We reviewed 8484 consecutive term pregnancies of women who delivered in our hospital, between years 1999-2001 before the introduction of guideline and years 2003-2005 following the guideline.


RESULTS
In group 1999-2001 there were 12/3581 (3.35 per thousand) neonates with EOGBS infection in which 7/3581 (1.96 per thousand) had invasive disease. In group 2003-2005 there were 14/4903 (2.86 per thousand) neonates with EOGBS infection (p=68,33%), in which 6/4903 (1,22 per thousand) had invasive disease (p=39,52%). Number of screened women in years 2003-2005 increased from 40% to 65%, and 69% respectively. There were 577/3019 (19%) of GBS colonized women.


CONCLUSIONS
There was 15% decrease of EOGBS disease following the introduction of guideline. Number of screened women increased by 29% in three-year period. GBS colonization in pregnant women is 19%.
Simetka
O
O
Porodnicko-gynekologická klinika, FN Ostrava. ondrej.simetka@fnspo.cz
Petros
M
M
Podesvová
H
H
D018153:Czech Republic; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D015997:Neonatal Screening; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis / Q000517:prevention & control*; D013292:Streptococcus agalactiae