[Efficacy and tolerability of short courses of nonsteroid anti-inflammatory drugs in the treatment of dorsalgia: results of the comparative study].
Efficacy of different nonsteroid anti-inflammatory drugs (voltaren (diclofenac), movalis (meloxicam), nimesil (nimesulide) and xefocam (lornoxicam) in stopping the pain syndrome and normalization of motor activity was assessed in 140 patients with dorsalgia using the Visual Analogous Scale and the modified Waddel scale. Moreover, we suggest a method for calculating a treatment efficacy coefficient. The most effective drug in the treatment of back pain was xefocam (lornoxicam). Nimesil (nimesulide) was somewhat less effective. Other drugs did not reveal any significant effect. Xefocam was well-tolerated: adverse effects were rare compared to other drugs used in the study.
Koval'chuk
V V
VV
Efimov
M A
MA
D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001416:Back Pain / Q000188:drug therapy* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D010147:Pain Measurement; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D013449:Sulfonamides / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; D010894:Piroxicam; C059451:lornoxicam; C012655:nimesulide