Structural and DNA cleavage of sugar-derived Schiff base ligands and their dinuclear Cu(II) complexes.
Neutral dinuclear Cu(II) complexes of Schiff base ligands derived from D-glucose have been synthesized and structurally characterized. These complexes were evaluated for their interaction with DNA, and DNA cleavage was observed even in the presence of radical inhibitors.
Nagarajan
Subbiah
S
Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India.
Kumbhar
Anupa
A
Varghese
Babu
B
Das
Thangamuthu Mohan
TM
D002241:Carbohydrates / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004247:DNA / Q000378:metabolism*; D006031:Glycosylation; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D012545:Schiff Bases / Q000737:chemistry*
D002241:Carbohydrates; D008024:Ligands; D009942:Organometallic Compounds; D012545:Schiff Bases; D003300:Copper; D004247:DNA