Antisocial networking in T helper cells.
T helper cell differentiation is controlled by a network of transcription factors. In this issue of Immunity, Yagi et al. (2010) describe the opposing effects of transcription factors Runx3 and GATA3 in the network promoting T helper 1 cell development.
Pham
Duy
D
Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 West Walnut St. Indianapolis, IN 46202, USA.
Kaplan
Mark H
MH