title: Optofluidic platforms based on surface-enhanced Raman scattering.
abstract: We report recent progress in the development of surface-enhanced Raman scattering (SERS)-based optofluidic platforms for the fast and sensitive detection of chemical and biological analytes. In the current context, a SERS-based optofluidic platform is defined as an integrated analytical device composed of a microfluidic element and a sensitive Raman spectrometer. Optofluidic devices for SERS detection normally involve nanocolloid-based microfluidic systems or metal nanostructure-embedded microfluidic systems. In the current review, recent advances in both approaches are surveyed and assessed. Additionally, integrated real-time sensing systems that combine portable Raman spectrometers with microfluidic devices are also reviewed. Such real-time sensing systems have significant utility in environmental monitoring, forensic science and homeland defense applications.
authors.affiliation: Department of Bionano Engineering, Hanyang University, Ansan 426-791, South Korea.
authors.forename: Chaesung
authors.initials: C
authors.lastname: Lim
authors.forename: Jongin
authors.initials: J
authors.lastname: Hong
authors.forename: Bong Geun
authors.initials: BG
authors.lastname: Chung
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: deMello
authors.forename: Jaebum
authors.initials: J
authors.lastname: Choo
mesh_terms: D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods; D008904:Miniaturization; D049329:Nanostructures / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods