title: The use of isotretinoin in acne.
abstract: Systemic isotretinoin remains the most efficacious treatment for severe acne as well as many cases of more moderate disease that are unresponsive to other treatment modalities. The current chapter outlines the mechanisms behind the excellent efficacy, describes how to optimize treatment, reviews the recommended guidelines for monitoring and summarizes adverse effects.
authors.affiliation: Harrogate Foundation Trust; Dermatology; Harrogate and District Foundation Trust; Harrogate, North Yorkshire UK.
authors.forename: Alison
authors.initials: A
authors.lastname: Layton