High prevalence of narrow angles among Filipino-American patients.
OBJECTIVE
To determine the prevalence of gonioscopically narrow anterior chamber angles in a Filipino-American clinic population.


METHODS
The records of 122 consecutive, new, self-declared Filipino-American patients examined in a comprehensive ophthalmology clinic in Vallejo, California were reviewed retrospectively. After exclusion, 222 eyes from 112 patients remained for analysis. Data were collected for anterior chamber angle grade as determined by gonioscopy (Shaffer system), age, sex, manifest refraction (spherical equivalent), intraocular pressure, and cup-to-disk ratio. Data from both eyes of patients were included and modeled using standard linear mixed-effects regression. As a comparison, data were also collected from a group of 30 consecutive White patients from the same clinic. After exclusion, 50 eyes from 25 White patients remained for comparison.


RESULTS
At least 1 eye of 24% of Filipino-American patients had a narrow anterior chamber angle (Shaffer grade ≤ 2). Filipino-American angle grade significantly decreased with increasingly hyperopic refraction (P=0.007) and larger cup-to-disk ratio (P=0.038). Filipino-American women had significantly decreased angle grades compared with men (P=0.028), but angle grade did not vary by intraocular pressure or age (all, P≥ 0.059).


CONCLUSIONS
Narrow anterior chamber angles are highly prevalent in Filipino-American patients in our clinic population.
Seider
Michael I
MI
Department of Ophthalmology, University of California-San Francisco, 10 Koret Street, San Francisco, CA 94143, USA.
Sáles
Christopher S
CS
Lee
Roland Y
RY
Agadzi
Anthony K
AK
Porco
Travis C
TC
Weinreb
Robert N
RN
Lin
Shan C
SC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000473:pathology*; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis / Q000208:ethnology*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D010679:Philippines / Q000208:ethnology; D015995:Prevalence; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology; D044465:White People