Anticoagulation and psychotropic medications.
Anticoagulants and psychotropic medications are commonly prescribed together. Thus, the potential for interaction exists. Whereas thrombolytics and heparins are implicated in few pharmacokinetic interactions, warfarin and platelet inhibitors have been implicated in various interactions with psychotropic medications. In this article, I review the various psychotropic drug classes' relationships to anticoagulants. In a field devoid of randomized, placebo-controlled trials, clinical vigilance is advised when managing patients on concomitant therapy.
Bachawati
Maurice
M
George Washington University/Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA. mbachawati@gmail.com
D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D004347:Drug Interactions; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006304:Health Status; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D009203:Myocardial Infarction / Q000517:prevention & control*; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D013923:Thromboembolism / Q000517:prevention & control*
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D011619:Psychotropic Drugs