title: Risk factors for bacteremia with uropathogen not cultured from urine in adults with febrile urinary tract infection.
abstract: In a prospective study involving 642 patients with febrile urinary tract infection (UTI), we found antimicrobial pretreatment (odds ratio [OR], 3.3), an indwelling urinary catheter (OR, 2.8), and malignancy (OR, 2.7) to be independent risk factors for bacteremia with a uropathogen that was not cultured or recognized in the urine. Although the diagnostic value of blood cultures has been questioned in UTI, we advocate performing blood cultures for patients with these risk factors.
authors.affiliation: Departments of Infectious Diseases , Bronovo Hospital, the Netherlands. c.van_nieuwkoop@lumc.nl
authors.forename: Cees
authors.initials: C
authors.lastname: van Nieuwkoop
authors.forename: Tobias N
authors.initials: TN
authors.lastname: Bonten
authors.forename: Jan W Van't
authors.initials: JW
authors.lastname: Wout
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Becker
authors.forename: Geert H
authors.initials: GH
authors.lastname: Groeneveld
authors.forename: Casper L
authors.initials: CL
authors.lastname: Jansen
authors.forename: Eric R
authors.initials: ER
authors.lastname: van der Vorm
authors.forename: Ed P
authors.initials: EP
authors.lastname: Ijzerman
authors.forename: Philip H
authors.initials: PH
authors.lastname: Rothbarth
authors.forename: Etel M
authors.initials: EM
authors.lastname: Termeer-Veringa
authors.forename: Ed J
authors.initials: EJ
authors.lastname: Kuijper
authors.forename: Jaap T
authors.initials: JT
authors.lastname: van Dissel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000453:epidemiology*; D002408:Catheters, Indwelling / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D011446:Prospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000150:complications* / Q000382:microbiology; D014556:Urine / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents