title: [Hormonal therapy in systemic lupus erythematosus].
abstract: Estrogens favor the development and/or exacerbation of systemic lupus erythematosus (SLE). Numerous reports have described the association between estrogens exposure (oral contraceptives and menopause hormonal therapy) and development or exacerbation of SLE. Some new studies showed benefit from oral contraceptives and other hormonal therapies without a change in lupus activity but with increased risk of thrombosis. Hormonal therapy in SLE patients should be individual according to clinical presentation and progression of the disease.
authors.affiliation: Odsjek za klinicku imunologiju i reumatologiju, Klinika za unutarnje bolesti Klinicki bolnicki centar Split, Soltanska 1, 21000 Split.
authors.forename: Dusanka Martinović
authors.initials: DM
authors.lastname: Kaliterna
authors.forename: Danijela Marasović
authors.initials: DM
authors.lastname: Krstulović
authors.forename: Mislav
authors.initials: M
authors.lastname: Radić
mesh_terms: D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D004967:Estrogens / Q000502:physiology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D003278:Contraceptives, Oral, Hormonal; D004967:Estrogens