Branching morphogenesis: Rac signaling "PIX" tubulogenesis. Focus on "Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanism".
Marrs
James A
JA
D000199:Actins / Q000378:metabolism; D000818:Animals; D018929:Cell Culture Techniques; D002460:Cell Line; D048430:Cell Shape; D024042:Collagen Type I / Q000378:metabolism; D003560:Cysts / Q000201:enzymology* / Q000473:pathology; D003599:Cytoskeleton / Q000378:metabolism; D004285:Dogs; D004847:Epithelial Cells / Q000201:enzymology* / Q000473:pathology; D020662:Guanine Nucleotide Exchange Factors / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D019012:Integrin beta1 / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology* / Q000473:pathology; D009024:Morphogenesis; D009154:Mutation; D018994:Myosin Light Chains / Q000378:metabolism; D010766:Phosphorylation; D064067:Rho Guanine Nucleotide Exchange Factors; D015398:Signal Transduction; D013997:Time Factors; D054462:p21-Activated Kinases / Q000235:genetics / Q000378:metabolism*; D020744:rac GTP-Binding Proteins / Q000378:metabolism*
D000199:Actins; D024042:Collagen Type I; D020662:Guanine Nucleotide Exchange Factors; D019012:Integrin beta1; D018994:Myosin Light Chains; D064067:Rho Guanine Nucleotide Exchange Factors; C515903:PAK1 protein, human; D054462:p21-Activated Kinases; D020744:rac GTP-Binding Proteins