title: Organocatalytic asymmetric aza-Nazarov cyclization of an azirine.
abstract: An unusual organocatalytic asymmetric cyclization of a ketoazirine that is accompanied by a kinetic resolution leads to 4-hydroxy-3-oxo-1,2,3,6-tetrahydropyridine-2-carboxylates in >99/1 er.
authors.affiliation: Department of Chemistry, University of Hawaii, 2545 The Mall, Honolulu, HI 96822, USA.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Shimada
authors.forename: Bradley O
authors.initials: BO
authors.lastname: Ashburn
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Basak
authors.forename: William F
authors.initials: WF
authors.lastname: Bow
authors.forename: David A
authors.initials: DA
authors.lastname: Vicic
authors.forename: Marcus A
authors.initials: MA
authors.lastname: Tius
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D001389:Azirines / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D008968:Molecular Conformation
chemical_list: D001372:Aza Compounds; D001389:Azirines