title: Lyme disease: a review.
abstract: Lyme disease is the most common vector-borne illness in the United States and is also endemic in Europe and Asia. It is caused by the spirochete Borrelia burgdorferi and transmitted by the bite of the Ixodes (deer) tick. It occurs most frequently during spring and summer and may involve the skin, nervous system, heart, and joints. This article reviews the pathogenesis, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of Lyme disease.
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11 N234, Bethesda, MD 20892, USA. amarques@niaid.nih.gov
authors.forename: Adriana R
authors.initials: AR
authors.lastname: Marques
mesh_terms: D000818:Animals; D025065:Borrelia burgdorferi / Q000472:pathogenicity*; D006801:Humans; D007303:Insect Vectors; D018884:Ixodes; D008193:Lyme Disease / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000503:physiopathology / Q000517:prevention & control