title: For good measure: Origins and prospects of exposure science (2007 Wesolowski Award Lecture).
abstract: Measurement is the foundation of exposure science. Associations between illness and environmental agents have been observed for millennia, but the ability to quantify exposure and dose has been possible only in the last century. Improved means of measurement and refined concepts of who, what, when, where, and why to measure have been the seminal contributions of exposure science to the study of disease causation and prevention. This paper examines critical advancements in exposure assessment associated with workplace health and safety, and the groundbreaking work of the US Public Health Service. Many of the key concepts of modern exposure science have their origin in these early studies. Occupational hygiene scientists have conducted receptor-based exposure analyses for more than 80 years, evaluating indoor air, defining microenvironments, and developing personal sampling techniques. Biological monitoring of community populations including children, dermal exposure monitoring, duplicate diet studies, and multi-pathway, aggregate exposure assessments can be traced to early public health studies. As we look to the future, we see that new technologies and techniques are expanding the scope of exposure science dramatically. We need to ensure that the highest of scientific standards are maintained, make a greater effort to include occupational hygiene scientists, microbiologists, and behavioral scientists in the field, and promote new sources of training and research support. Exposure science has a critical role to play in the prevention strategy that is central to public health.
authors.affiliation: Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, 98195, USA. rfenske@u.washington.edu
authors.forename: Richard A
authors.initials: RA
authors.lastname: Fenske
mesh_terms: D000393:Air Pollutants / Q000032:analysis; D000397:Air Pollution / Q000032:analysis; D001363:Awards and Prizes; D004463:Ecology; D004781:Environmental Exposure / Q000032:analysis / Q000517:prevention & control / Q000592:standards; D004784:Environmental Monitoring / Q000379:methods / Q000592:standards; D005506:Food Contamination / Q000032:analysis / Q000517:prevention & control; D006801:Humans; D015980:Public Health Practice; D018570:Risk Assessment / Q000379:methods; D014481:United States; D014492:United States Public Health Service
chemical_list: D000393:Air Pollutants