title: LASIK correction of vision in adults with unilateral amblyopia.
abstract: OBJECTIVE
  to evaluate the effects of laser refractive surgery in adult patients with mild to moderate amblyopia due to anisometropic myopia.
  
  
  METHODS
  a retrospective review of 30 patients (60 eyes) with unilateral amblyopia (corrected distance visual acuity [CDVA] 0.6 or worse) who underwent simultaneous bilateral laser vision correction using the Technolas 217z excimer laser (Bausch & Lomb) was performed. Mean patient age was 31.03 ± 10.05 years (range: 18 to 53 years). Visual outcomes in the amblyopic eye were compared with those in the fellow nonamblyopic control eye of the same patient.
  
  
  RESULTS
  mean preoperative CDVA improved in amblyopic eyes from 0.50 ± 0.13 to 0.57 ± 0.20 postoperatively (average gain of 0.075 ± 0.14; P=.007) and improved from 0.92 ± 0.12 preoperatively to 0.93±0.15 after surgery (mean gain of 0.013 ± 0.14; P=.603) in the fellow nonamblyopic eyes. The safety index was significantly greater in the amblyopic eyes compared with the nonamblyopic fellow eyes (1.15 ± 0.30 vs 1.02 ± 0.15, P=.035), therefore, no difference was noted in efficacy (P=.913). Five of 30 eyes with mild to moderate amblyopia gained 2 to 4 lines of CDVA.
  
  
  CONCLUSIONS
  laser refractive surgery for myopic correction was found to be safe and effective in eyes with mild to moderate amblyopia.
authors.affiliation: Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. faikorucov@yahoo.co.uk
authors.forename: Faik
authors.initials: F
authors.lastname: Oruçoğlu-Orucov
authors.forename: Joseph
authors.initials: J
authors.lastname: Frucht-Pery
authors.forename: David
authors.initials: D
authors.lastname: Landau
authors.forename: Eyal
authors.initials: E
authors.lastname: Strasman
authors.forename: Abraham
authors.initials: A
authors.lastname: Solomon
mesh_terms: D000293:Adolescent; D000328:Adult; D000550:Amblyopia / Q000503:physiopathology / Q000601:surgery*; D015858:Anisometropia / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult