title: Antisocial networking in T helper cells.
abstract: T helper cell differentiation is controlled by a network of transcription factors. In this issue of Immunity, Yagi et al. (2010) describe the opposing effects of transcription factors Runx3 and GATA3 in the network promoting T helper 1 cell development.
authors.affiliation: Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 West Walnut St. Indianapolis, IN 46202, USA.
authors.forename: Duy
authors.initials: D
authors.lastname: Pham
authors.forename: Mark H
authors.initials: MH
authors.lastname: Kaplan