Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer.
OBJECTIVE
The aim of this study was to compare magnetic resonance imaging (MRI) with positron emission tomography/computed tomography (PET/CT) in the preoperative detection of lymph node metastases in patients with uterine cervical cancer.


METHODS
This retrospective study reviewed patients with cervical cancer who had undergone both preoperative MRI and PET/CT before radical surgery, including lymphadenectomy between 2004-2008.


RESULTS
Eighty-three patients were identified, of whom 28 (33.7%) had pelvic lymph node metastasis. The sensitivity, specificity, and accuracy for detecting lymph node metastasis were 64.3%, 69.1%, and 67.5% for MRI, and 28.6%, 83.6%, and 65.1% for PET/CT, respectively. The area under the receiver operating characteristics for the MRI and PET/CT were 0.667 and 0.561, respectively (P = .013). MRI showed significantly higher sensitivity for detecting metastatic lymph nodes than PET/CT (P = .006).


CONCLUSIONS
MRI was more sensitive than PET/CT for detecting metastatic lymph node in patients with cervical cancer.
Chung
Hyun Hoon
HH
Department of Obstetrics and Gynecology and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kang
Keon Wook
KW
Cho
Jeong Yeon
JY
Kim
Jae Weon
JW
Park
Noh-Hyun
NH
Song
Yong-Sang
YS
Kim
Seung Hyup
SH
Chung
June-Key
JK
Kang
Soon-Beom
SB
D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011300:Preoperative Care / Q000379:methods; D011336:Probability; D012372:ROC Curve; D012189:Retrospective Studies; D012380:Role; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D055815:Young Adult