Molecular monitoring of viral infections after hematopoietic stem cell transplantation.
Viral infections are important complications after allogeneic hematopoietic stem cell transplantation. Viral load monitoring combined with preemptive antiviral therapy has become an established strategy for the management of CMV infections. This review discusses and summarizes information regarding viral load monitoring for EBV, human herpesvirus 6, and adenoviruses including virological and clinical aspects. Standardized assays are lacking for these viruses and additional studies are needed.
Ljungman
Per
P
Department of Hematology, Karolinska University Hospital, Stockholm, Sweden. per.ljungman@ki.se
D004279:DNA, Viral / Q000097:blood*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016133:Polymerase Chain Reaction; D019562:Viral Load; D014777:Virus Diseases / Q000097:blood / Q000175:diagnosis* / Q000821:virology*
D004279:DNA, Viral