Clinical characteristics of delayed endolymphatic hydrops in Japan: A nationwide survey by the Peripheral Vestibular Disorder Research Committee of Japan.
CONCLUSIONS
Similarly to almost all delayed endolymphatic hydrops (DEH) cases with both precedent sudden deafness and mumps deafness, two-thirds of DEH cases with precedent deafness of unknown cause with onset in early childhood developed DEH symptoms within 40 years after the precedent deafness. In spite of the diagnosis of precedent deafness, viral labyrinthitis may build up the late endolymphatic hydrops in most DEH cases up to four decades.


OBJECTIVE
To clarify the characteristics of DEH in Japan.


METHODS
Clinical information on 198 DEH cases was collected by nationwide, multicenter surveys conducted by the Peripheral Vestibular Disorders Research Committee of Japan.


RESULTS
The incidence of the ipsilateral type of DEH was 47.5%, which was almost equal to that of the contralateral type. In both types of DEH, the most common diagnosis of precedent deafness was deafness of unknown cause with onset in early childhood: 43.9% in both types of DEH. Sudden deafness and mumps deafness were the subsequent diagnoses of precedent deafness. The distribution of time delay of the onset between precedent deafness of unknown cause with onset in early childhood and DEH was different from that between precedent sudden and mumps deafness and DEH.
Shojaku
Hideo
H
Departments of Otolaryngology, University of Toyama, Japan. hshojaku@med.u-toyama.ac.jp
Watanabe
Yukio
Y
Takeda
Noriaki
N
Ikezono
Tetsuo
T
Takahashi
Masahiro
M
Kakigi
Akinobu
A
Ito
Juichi
J
Doi
Katsumi
K
Suzuki
Mamoru
M
Takumida
Masaya
M
Takahashi
Katsumasa
K
Yamashita
Hiroshi
H
Koizuka
Izumi
I
Usami
Shinichi
S
Aoki
Mitsuhiro
M
Naganuma
Hideaki
H
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D035843:Biomedical Research; D002648:Child; D002675:Child, Preschool; D003638:Deafness / Q000453:epidemiology* / Q000209:etiology; D018159:Endolymphatic Hydrops / Q000150:complications / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult