title: Access to original vinylic chlorides in the quinazoline series via a monoelectronic transfer reaction approach.
abstract: A series of new quinazoline derivatives bearing a vinylic chloride group on the 2-position was prepared by using a consecutive S(RN)1 / E(RC)1 radical strategy.
authors.affiliation: Laboratoire de Pharmacochimie Radicalaire, Faculté de Pharmacie, Universités d'Aix-Marseille I, II et III - UMR CNRS 6264, Laboratoire Chimie Provence, 27 Boulevard Jean Moulin, Marseille cedex 05, France. martine.maillard@univmed.fr
authors.forename: Martine
authors.initials: M
authors.lastname: Maillard-Boyer
authors.forename: Caroline
authors.initials: C
authors.lastname: Castera-Ducros
authors.forename: Pierre
authors.initials: P
authors.lastname: Verhaeghe
authors.forename: France
authors.initials: F
authors.lastname: Sifredi
authors.forename: Pascal
authors.initials: P
authors.lastname: Rathelot
authors.forename: Patrice
authors.initials: P
authors.lastname: Vanelle
mesh_terms: D000962:Antimalarials / Q000138:chemical synthesis / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry*; D047428:Protein Kinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry*; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry*; D014752:Vinyl Chloride / Q000737:chemistry*
chemical_list: D000962:Antimalarials; D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D014752:Vinyl Chloride