title: Assessment of Growth Disturbance in Japanese Children with IBD.
abstract: In Japan, there is as yet no report on growth retardation in children with IBD. We therefore investigated the cause of growth retardation in Japanese children with IBD. We investigated the height, body weight, serum levels of albumin, IGF-I, CRP, and cytokines, and the amount of corticosteroid administered in children with Crohn's disease (CD, n = 15) and ulcerative colitis (UC, n = 18). Our results suggest that growth retardation is already present before the initial visit in children with CD, and chronic inflammation may be responsible this growth disturbance. Moreover, the amount of PSL used may contribute to growth retardation by decreasing the serum levels of IGF-I in children with IBD.
authors.affiliation: Department of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shono
authors.forename: Mayuko
authors.initials: M
authors.lastname: Kato
authors.forename: Yo
authors.initials: Y
authors.lastname: Aoyagi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Haruna
authors.forename: Tohru
authors.initials: T
authors.lastname: Fujii
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kudo
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Ohtsuka
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shimizu
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