title: Breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport.
abstract: Pyruvate is the key substance controlling the formation of diacetyl, acetaldehyde, and acetate during alcoholic fermentation. Here we report the breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport. Mitochondrial function was involved in resistance to this substance and in the production of pyruvate by the mutants.
authors.affiliation: Faculty of Agriculture, Saga University, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Horie
authors.forename: Takahiro
authors.initials: T
authors.lastname: Oba
authors.forename: Saori
authors.initials: S
authors.lastname: Motomura
authors.forename: Atsuko
authors.initials: A
authors.lastname: Isogai
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshimura
authors.forename: Keisuke
authors.initials: K
authors.lastname: Tsuge
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Koganemaru
authors.forename: Genta
authors.initials: G
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kitagaki
mesh_terms: D000085:Acetates / Q000378:metabolism; D000434:Alcoholic Beverages; D000435:Alcoholic Intoxication / Q000235:genetics / Q000378:metabolism; D057229:Alcoholics; D001692:Biological Transport / Q000235:genetics; D001947:Breeding; D005285:Fermentation / Q000235:genetics; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism*; D019289:Pyruvic Acid / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D015003:Yeasts / Q000235:genetics
chemical_list: D000085:Acetates; D011773:Pyruvates; D019289:Pyruvic Acid