title: Time to stable ST-segment recovery following primary angioplasty is predictive of regional wall motion score and clinical outcome.
abstract: We report the time to stable ST-segment reperfusion (TSTR) after primary angioplasty and its relationship with the clinical results; 137 patients who underwent primary angioplasty were included as part of the analysis. All patients had 24 hours ST-segment monitoring. Time to stable STR was defined as the beginning of ST-segment reperfusion (STR) lasting >4 hours without ST-segment reelevation. Six-month mortality was associated with slower TSTR (median 166.5 vs 6 minute, P = .001). Time to stable STR cutoff value of 136.5 minutes was identified as the best mortality predictor (area under the curve: 0.86, P = .001). Multivariate analysis identified Killip class > or = 2 (P = .042), TSTR cutoff value (P = .002), and final thrombolysis myocardial infarction (TIMI) flow grade III (P = .067) as predictors of 6-month mortality. Time to stable STR may be a novel continuous electrocardiogram (ECG) parameter following primary angioplasty, which can identify high-risk patients that need to be considered for additional treatments.
authors.affiliation: Department of Interventional Cardiology and Endovascular Therapeutics, Instituto Cardiovascular de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina. marianoalbertal@gmail.com
authors.forename: Mariano
authors.initials: M
authors.lastname: Albertal
authors.forename: Fernando
authors.initials: F
authors.lastname: Cura
authors.forename: Jorge
authors.initials: J
authors.lastname: Thierer
authors.forename: Marcelo
authors.initials: M
authors.lastname: Trivi
authors.forename: Alejandro G
authors.initials: AG
authors.lastname: Escudero
authors.forename: Lucio T
authors.initials: LT
authors.lastname: Padilla
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Belardi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D004562:Electrocardiography; D006440:Hemofiltration / Q000295:instrumentation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D015425:Myocardial Reperfusion; D020127:Recovery of Function; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome