Tissue microarray for routine clinical breast biomarker analysis. The British Columbia Cancer Agency 2008 experience.
Clinical use of tissue microarrays for immunohistochemical analysis of breast biomarkers, namely estrogen receptor, progesterone receptor, and HER2, was instituted in our laboratory in 2008. The method has proved reliable and cost-effective. We report the results of the initial year of testing with this method.
Thomson
Thomas A
TA
Department of Laboratory Medicine, British Columbia Cancer Agency, 600 W 10th Ave., Vancouver, BC, Canada.
Zhou
Chen
C
Ceballos
Kathy
K
Knight
Bryan
B
D014408:Biomarkers, Tumor / Q000032:analysis*; D001940:Breast / Q000737:chemistry*; D001943:Breast Neoplasms / Q000737:chemistry*; D001955:British Columbia; D002886:Chromosomes, Human, Pair 17 / Q000737:chemistry; D006801:Humans; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis; D046888:Tissue Array Analysis / Q000191:economics
D014408:Biomarkers, Tumor; D018719:Erb-b2 Receptor Tyrosine Kinases; D011960:Receptors, Estrogen; C508053:ERBB2 protein, human