The mucosal immune response to plant-derived vaccines.
Transgenic plants present enormous potential as one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary and agricultural uses. Heat-stable plant-derived vaccines that are administered orally could in effect enhance vaccine coverage in children and infants, particularly in developing countries. Here we discuss the current status of plant-derived vaccines and their potential to champion the battle against infectious diseases in the least developed countries.
Hefferon
Kathleen Laura
KL
Cornell Research Foundation, Cornell University, 395 Pine Tree Rd Suite 310, Ithaca, NY 14850, USA. klh22@cornell.edu
D001709:Biotechnology / Q000379:methods*; D003141:Communicable Diseases / Q000276:immunology; D003906:Developing Countries; D006801:Humans; D018928:Immunity, Mucosal; D046549:Plantibodies / Q000276:immunology*; D030821:Plants, Genetically Modified / Q000378:metabolism*; D022462:Vaccines, Edible / Q000096:biosynthesis / Q000276:immunology; D014614:Vaccines, Synthetic / Q000096:biosynthesis* / Q000276:immunology
D046549:Plantibodies; D022462:Vaccines, Edible; D014614:Vaccines, Synthetic
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