title: Neuropsychological decline/improvement in opsoclonus myoclonus ataxia.
abstract: Opsoclonus myoclonus ataxia (OMA) is a rare neurological disorder (incidence = approximately 1/5 million) primarily associated with involuntary conjugate saccadic eye movements, involuntary muscle jerks, cerebellar ataxia, and neuropsychological impairments. Unfortunately, there is limited published data regarding the nature and course of neuropsychological impairments following OMA diagnosis and treatment. This study presents neuropsychological data obtained at 1, 4, and 18 months post-diagnosis of a 52-year-old male with OMA. The patient initially demonstrated significant global neurocognitive, psychomotor, and psychological difficulties with substantial improvement over time. Treatment included medication management, physical rehabilitation, and psychological intervention.
authors.affiliation: Department of Health Psychology, University of Missouri, Columbia, MO, USA. mariansmith2@gmail.com
authors.forename: Marian L
authors.initials: ML
authors.lastname: Smith
authors.forename: Neil
authors.initials: N
authors.lastname: Thawani
authors.forename: Brick
authors.initials: B
authors.lastname: Johnstone
authors.forename: Renee
authors.initials: R
authors.lastname: Stucky
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D053578:Opsoclonus-Myoclonus Syndrome / Q000503:physiopathology* / Q000628:therapy