Regulation of skeletal myogenesis by Notch.
Notch signaling has emerged as a key player in skeletal muscle development and regeneration. Simply stated, Notch signaling inhibits differentiation. Accordingly, fine-tuning the pathway is essential for proper muscle homeostasis. This review will address various aspects of Notch signaling, including our current views of the core pathway, its effects in muscle, its interactions with other signaling pathways, and its relationship with ageing.
Buas
Matthew F
MF
Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6145, USA.
Kadesch
Tom
T
D000818:Animals; D006801:Humans; D024510:Muscle Development / Q000502:physiology*; D018482:Muscle, Skeletal / Q000254:growth & development*; D051880:Receptors, Notch / Q000502:physiology*; D015398:Signal Transduction
D051880:Receptors, Notch
Genes Dev. 2002 Aug 1;16(15):1964-76
12154126
Blood. 2007 Nov 15;110(10):3618-23
17699740
Exp Cell Res. 2004 Jun 10;296(2):173-82
15149848
Sci Signal. 2009 Jan 27;2(55):ra1
19176515
Stem Cells. 2009 Nov;27(11):2769-80
19785007
Mol Cell Biol. 1999 Apr;19(4):2853-62
10082551
Science. 1995 Apr 14;268(5208):225-32
7716513
Dev Cell. 2005 Nov;9(5):617-28
16256737
Development. 1994 Sep;120(9):2385-96
7956819
J Biol Chem. 2009 Sep 25;284(39):26427-38
19567869
Nature. 2005 Feb 17;433(7027):760-4
15716955
Development. 1999 Apr;126(8):1689-702
10079231
Dev Cell. 2002 Aug;3(2):221-31
12194853
Genes Dev. 1998 Aug 1;12(15):2269-77
9694793
Mol Cell. 2004 Nov 19;16(4):509-20
15546612
J Biol Chem. 2010 Jan 8;285(2):1249-58
19917614
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3368-73
18299578
J Clin Invest. 2007 Sep;117(9):2477-85
17717603
Cell. 1995 Mar 24;80(6):909-17
7697721
Genes Dev. 2001 Nov 15;15(22):2950-66
11711431
J Cell Physiol. 2009 Jan;218(1):84-93
18727102
Genes Dev. 2007 Jun 1;21(11):1322-7
17545467
Genes Dev. 2002 Jun 1;16(11):1397-411
12050117
Dev Cell. 2002 Sep;3(3):397-409
12361602
J Biol Chem. 2007 Feb 2;282(5):3058-65
17158101
Genes Dev. 1995 Dec 15;9(24):3136-48
8543157
Cell. 2009 Apr 17;137(2):216-33
19379690
Nature. 2008 Jul 24;454(7203):528-32
18552838
Cell Stem Cell. 2009 Jun 5;4(6):535-47
19497282
Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4443-8
17360543
Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):537-42
17194759
Nat Rev Mol Cell Biol. 2008 May;9(5):355-66
18431399
Development. 2003 Dec;130(24):6089-99
14597575
Mol Cell Biol. 2005 Dec;25(23):10379-90
16287852
Cell Stem Cell. 2008 Jan 10;2(1):50-9
18371421
EMBO J. 2002 Oct 15;21(20):5417-26
12374742
J Biol. 2009;8(4):44
19486506
Genes Dev. 1992 Dec;6(12B):2620-34
1340473
Science. 2003 Nov 28;302(5650):1575-7
14645852
J Cell Biol. 2006 Nov 20;175(4):535-40
17116748
Cell. 2007 Jun 1;129(5):999-1010
17540178
Genes Dev. 2006 Mar 15;20(6):675-88
16510869
Nature. 2000 Jun 22;405(6789):966-70
10879540
Development. 1996 Dec;122(12):3765-73
9012498
Nature. 1995 Sep 28;377(6547):355-8
7566092