Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis.
The objective of this study was to investigate the course of suicidal behavior over the first 2 years of comprehensive, integrated treatment in two groups of patients with DSM-IV first episode schizophrenia spectrum psychosis, where one group was recruited through an early detection program. We have previously shown that the rate of severe suicidal behavior was lower in the earlier detected group than in the other. First episode schizophrenia is a high risk period for suicidality, but we found low rates of completed suicides and suicide attempts in both groups after 2 years in treatment, with no between-groups differences. Severe suicidality (plans and attempts) was predicted by drug abuse, dissatisfaction with life and severe suicidality at start of treatment.
Melle
Ingrid
I
Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway. ingrid.melle@medisin.uio.no
Johannessen
Jan Olav
JO
Friis
Svein
S
Haahr
Ulrik
U
Joa
Inge
I
Larsen
Tor K
TK
Opjordsmoen
Stein
S
Rund
Bjørn R
BR
Simonsen
Erik
E
Vaglum
Per
P
McGlashan
Thomas
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D039721:Diagnostic and Statistical Manual of Mental Disorders; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011613:Psychotherapy / Q000379:methods*; D011618:Psychotic Disorders / Q000453:epidemiology* / Q000628:therapy*; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data*; D013997:Time Factors; D055815:Young Adult