Post-transplant lymphoproliferative disorder following cytomegalovirus reactivation in a lung recipient.
Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation, for which several risk factors including pretransplant seronegativity for Epstein-Barr virus are known. However, the impact of cytomegalovirus on PTLD remains to be determined. Here, we describe a case of Epstein-Barr virus-associated polymorphic PTLD that developed shortly after treatment for cytomegalovirus reactivation in a lung transplant recipient who was preoperatively seropositive for both cytomegalovirus and Epstein-Barr virus.
Aoyama
Akihiro
A
Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Omasa
Mitsugu
M
Kondo
Nobuyuki
N
Chen
Fengshi
F
Date
Hiroshi
H
Bando
Toru
T
D000998:Antiviral Agents / Q000008:administration & dosage; D001706:Biopsy; D003587:Cytomegalovirus / Q000472:pathogenicity*; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D015774:Ganciclovir / Q000008:administration & dosage; D004854:Herpesvirus 4, Human / Q000472:pathogenicity*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016040:Lung Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome; D014740:Vidarabine / Q000008:administration & dosage; D014775:Virus Activation
D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D014740:Vidarabine; D015774:Ganciclovir
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