[Pathogenis surveillance of epidemic cerebrospinal meningitis in Shandong Province in 2007/2008].
OBJECTIVE
To understander Neisseria meningitides (Nm) and antimicrobial susceptibility through analyzing the pathogens surveillance meningistis (ECM) cases and Nm carrier rate in healthy people in 2008.


METHODS
Nm strains were isolated, identified and tested of specimens of cerebrospinal fluid and serum were analyzed by real-time.


RESULTS
Seven Nm strains were isolated from ECM cases and close 4 serogroup C.44 Nm strains were isolated from 2323 healthy persons. strains include 11 serogroup A (25.00%), 16 serogroup B (36.36%), other serogroups (29.55%). The carrier rate was highest among the There is no significant statistical difference between males and females


CONCLUSIONS
Serogroup C and B were the dominant strains in ECM cases province. In healthy people, serogroup B was the dominant strain, C. Surveillance of pathogens and Nmantimicrobial susceptibility test strategies mainly based on vaccination should be strengthened.
Li
Man-Shi
MS
Shandong Provincial Centre for Disease Control and Prevention, Jinan 250014, Shandong, China.
Wang
Min
M
Fu
Zhong-Yan
ZY
D000293:Adolescent; D017677:Age Distribution; D000890:Anti-Infective Agents / Q000494:pharmacology; D002353:Carrier State / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002681:China; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000635:transmission; D009345:Neisseria meningitidis / Q000145:classification / Q000187:drug effects / Q000472:pathogenicity*; D012111:Residence Characteristics / Q000706:statistics & numerical data; D017678:Sex Distribution; D055815:Young Adult
D000890:Anti-Infective Agents