title: Kleine-Levin syndrome: current status.
abstract: Kleine-Levin Syndrome is a periodic hypersomnia characterized by recurrent episodes of hypersomnia and other symptoms. This article reviews the research to date, outlines the clinical symptoms, and describes current testing and treatment. It concludes that the cause remains unknown and no treatment is effective in preventing recurrence, although modafinil may reduce duration of symptomatic episode.
authors.affiliation: Sleep Center, Chang Gung Memorial Hospital and University, Taoyuan, Taiwan.
authors.forename: Yu-Shu
authors.initials: YS
authors.lastname: Huang
authors.forename: Clair
authors.initials: C
authors.lastname: Lakkis
authors.forename: Christian
authors.initials: C
authors.lastname: Guilleminault
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D003072:Cognition Disorders / Q000150:complications; D006801:Humans; D017593:Kleine-Levin Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000928:Antidepressive Agents; D000697:Central Nervous System Stimulants