title: Spindle cell liposarcoma of the face: case report and literature review.
abstract: Liposarcoma is a common soft tissue sarcoma accounting for approximately 20% of all mesenchymal tumours across all ages. Recently, collaborative research in the specialties of pathology and genetics has led to the delineation of several tumour variants with different behaviours and prognoses, one of which includes the very rare spindle cell liposarcoma (SCL) subtype. We present the first case of an SCL arising in the subcutaneous tissue of the forehead of a 78-year-old man. In light of the rarity of this tumour, we describe the tumour and its clinical and pathological characteristics and undertake a literature review to clarify the surgical management and prognosis of SCL, and increase awareness to avoid misdiagnosis of a benign soft tissue neoplasm.
authors.affiliation: AOUP Burn Center and Plastic Surgery Unit, Via Paradisa 2, Ospedale Cisanello, 56100 Pisa, Italy. tommasoagostini@ymail.com
authors.forename: T
authors.initials: T
authors.lastname: Agostini
authors.forename: C
authors.initials: C
authors.lastname: Catelani
authors.forename: A
authors.initials: A
authors.lastname: Acocella
authors.forename: A
authors.initials: A
authors.lastname: Franchi
authors.forename: R
authors.initials: R
authors.lastname: Bertolai
authors.forename: R
authors.initials: R
authors.lastname: Sacco
authors.forename: D
authors.initials: D
authors.lastname: Lazzeri
authors.forename: K
authors.initials: K
authors.lastname: Shokrollahi
mesh_terms: D000368:Aged; D005153:Facial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D005546:Forehead; D006801:Humans; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D011379:Prognosis; D011859:Radiography; D016896:Treatment Outcome