title: Glucosamine hydrochloride functionalized tetraphenylethylene: a novel fluorescent probe for alkaline phosphatase based on the aggregation-induced emission.
abstract: Grafting of glucosamine hydrochloride moieties to tetraphenylethylene (TPE) motif furnished a novel cationic water-soluble tetraphenylethylene derivative (GH-TPE). With aggregation-induced emission properties, GH-TPE was used for fluorometric detection to alkaline phosphatase through enzyme-triggered de-aggregation of the ensemble of GH-TPE and substrate.
authors.affiliation: National Center for Nanoscience and Technology, Beijing 100190, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Chen
authors.forename: Ning
authors.initials: N
authors.lastname: Bian
authors.forename: Chun
authors.initials: C
authors.lastname: Cao
authors.forename: Xi-Long
authors.initials: XL
authors.lastname: Qiu
authors.forename: Ai-Di
authors.initials: AD
authors.lastname: Qi
authors.forename: Bao-Hang
authors.initials: BH
authors.lastname: Han
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005470:Fluorometry / Q000379:methods*; D005944:Glucosamine / Q000031:analogs & derivatives* / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D013267:Stilbenes; D014230:Triazoles; D000469:Alkaline Phosphatase; D005944:Glucosamine