title: Cystic bone tuberculosis in children--a case series.
abstract: Cystic tuberculosis of the bone is a rare form of tuberculosis (TB) osteomyelitis associated with disseminated lesions. In children, the lesions involve the peripheral skeleton, are symmetric and less sclerotic while in adults, the lesions are axial and predominantly sclerotic. TB dactylitis and spina ventosa are the other common variants of TB osteomyelitis seen in children below five years. Here we report seven cases of cystic TB bone disease. There were three males and four females with age of diagnosis between 2-11 years. Most patients presented with localized swelling and pain. X-rays revealed classical cystic lesions and spina ventosa. Four children had multiple cystic lesions and three had isolated lesions. Diagnosis was confirmed by FNAC of the bone or histopathological/radiological evidence of TB. The patients responded well to anti-tubercular therapy. The entity of cystic TB bone disease should be borne in mind as, lack of awareness may delay diagnosis and treatment. Biopsy is mandatory to confirm diagnosis and antitubercular drugs are the mainstay of therapy. Curettage of affected bone in selected cases may promote early healing. Response to therapy is excellent and the overall prognosis is good.
authors.affiliation: Department of Pediatrics, TNMC & BYL Nair Hospital, Mumbai Central, Mumbai-400 008, Maharashtra. sushmamalik@hotmail.com
authors.forename: Sushma
authors.initials: S
authors.lastname: Malik
authors.forename: Surekha
authors.initials: S
authors.lastname: Joshi
authors.forename: J Sonali
authors.initials: JS
authors.lastname: Tank
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D001845:Bone Cysts / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology*; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D014394:Tuberculosis, Osteoarticular / Q000000981:diagnostic imaging* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents