title: Vertebral artery aneurysms and cervical arteriovenous fistulae in patients with neurofibromatosis 1.
abstract: Vascular involvement in the setting of neurofibromatosis type 1(NF1) has been well described. However, the coexistence of NF1 with vertebral artery (VA) aneurysms and arteriovenous fistulae (AVFs) is a rare occurrence. A 60-year-old female with NF1 and other severe comorbidities presented with acute respiratory insufficiency caused by a ruptured large VA aneurysm and an associated AVF that required emergent intubation and eventual repair through endovascular techniques that resolved her symptoms. A detailed description of this case and a comprehensive review of the literature are also presented.
authors.affiliation: Tucson Medical Center, AZ, USA.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Higa
authors.forename: John P
authors.initials: JP
authors.lastname: Pacanowski
authors.forename: David T
authors.initials: DT
authors.lastname: Jeck
authors.forename: Kaoru R
authors.initials: KR
authors.lastname: Goshima
authors.forename: Luis R
authors.initials: LR
authors.lastname: León
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D015901:Angiography, Digital Subtraction; D001164:Arteriovenous Fistula / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D002648:Child; D004621:Embolization, Therapeutic; D005260:Female; D005774:Gastrostomy; D006406:Hematoma / Q000209:etiology; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology; D012131:Respiratory Insufficiency / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014139:Tracheostomy; D016896:Treatment Outcome; D014711:Vertebral Artery / Q000000981:diagnostic imaging; D055815:Young Adult