Anodic oxidation of catechols in the presence of alpha-oxoketene N,N-acetals with a tetrahydropyrimidine ring: selective alpha-arylation reaction.
The electrochemical oxidation of catechols leads to the formation of o-benzoquinones. This property has been applied to effectively synthesize alpha-arylated products of alpha-oxoketene N,N-acetals with a tetrahydropyrimidine ring.
Zeng
Cheng-Chu
CC
College of Life Science & Bioengineering, Beijing University of Technology, Beijing, 100124, China. zengcc@bjut.edu.cn
Ping
Da-Wei
DW
Hu
Li-Ming
LM
Song
Xiu-Qing
XQ
Zhong
Ru-Gang
RG
D000080:Acetals / Q000737:chemistry*; D002396:Catechols / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D004583:Electrons; D005030:Ethylenes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D011743:Pyrimidines / Q000737:chemistry*; D013379:Substrate Specificity
D000080:Acetals; D002396:Catechols; D005030:Ethylenes; D007659:Ketones; D011743:Pyrimidines; C030986:pyrimidine; C008223:ketene; C034221:catechol