[Obesity and atherosclerosis--what's the link?].
Obesity, primarily abdominal obesity, is a significant risk factor for symptomatic atherosclerosis. Atherosclerotic vascular changes and the pandemic of obesity are connected with the civilization process, in particular with diet modification and shortage of exercise and physical effort. The clinically defined metabolic syndrome is the most prominent atherosclerotic risk factor based on adipose tissue dysfunction producing low grade inflammation and endothelial dysfunction.
Sucharda
P
P
3. interní klinika 1, lékarské fakulty UK a VFN Praha. petr.sucharda@lf1.cuni.cz
D050197:Atherosclerosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications; D009765:Obesity / Q000150:complications* / Q000503:physiopathology; D012307:Risk Factors