title: Longitudinal tissue velocity and deformation imaging in inferobasal left ventricular aneurysm.
abstract: BACKGROUND
  Longitudinal myocardial tissue velocity imaging (TVI) and strain rate imaging (SRI) quantify regional myocardial function. We aimed to measure TVI and SRI indices for inferobasal aneurysmal segments by echocardiography at rest.
  
  
  METHODS
  Sixteen patients with inferobasal left ventricular (LV) aneurysm, LV ejection fraction (EF) ≤50%, and 14 normal coronaries with normal echocardiography (control group) were studied. In SRI, peak systolic strain (ST), strain rate (SR), and pattern of strain curves and in TVI, peak systolic inward motion (Sm) were evaluated all at rest. Ascending curve means systolic expansion and descending means shortening.
  
  
  RESULTS
  LVEF was significantly lower in the patient group. Mean ST, SR, and Sm of inferobasal segment showed significant difference between patient and control groups; for ST: 1.45 ± 7.18% versus -17.64 ± 7.45%, P < 0.0001; SR: -0.25 ± 0.26 versus -1.44 ± 0.64 sec(-1) , P < 0.0001; and Sm: 3.85 ± 1.26 versus 5.56 ± 1.28 cm/sec, P = 0.006, respectively. All inferobasal aneurysmal segments had ascending curve while normal segments showed a descending curve. In patient group, aneurysmal segments had significantly reduced ST and SR compared to normal segments. Normal functioning segments of patients showed significant reduction of ST and SR compared to normal LV segments in control subjects. The range of SR and ST for inferobasal aneurysmal segments did not overlap with that of the normal segments (-0.60, 0.19 and -3.00, -0.80 sec(-1) for SR, and -8.30, 23.30 and -35.30, -10.00% for ST, respectively).
  
  
  CONCLUSIONS
  SRI indices were significantly reduced in inferobasal aneurysmal segment in comparison with either the same segment in normal subjects or normal functioning segments in the same patients. SR and ST may be superior to Sm in the evaluation of inferobasal aneurysmal segments.
authors.affiliation: Echocardiography Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hakimeh
authors.initials: H
authors.lastname: Sadeghian
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Ahmadi
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Lotfi-Tokaldany
authors.forename: Rezvanyieh
authors.initials: R
authors.lastname: Salehi
authors.forename: Reyhane
authors.initials: R
authors.lastname: Zavar
authors.forename: Mahmood Sheikh
authors.initials: MS
authors.lastname: Fathollahi
authors.forename: Seyed Hesameddin
authors.initials: SH
authors.lastname: Abbasi
mesh_terms: D016880:Anisotropy; D004452:Echocardiography / Q000379:methods*; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006322:Heart Aneurysm / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume