title: Perfusion MRI demonstrates crossed-cerebellar diaschisis in sickle cell disease.
abstract: Arterial spin labeling is a fully noninvasive magnetic resonance perfusion imaging method, ideally suited to pediatric perfusion imaging. We describe an 8-year-old boy with sickle cell disease, extensive right-hemispheric cerebral infarction, and crossed-cerebellar diaschisis apparent on arterial spin labeling perfusion magnetic resonance imaging. To our knowledge, this is the first case of crossed-cerebellar diaschisis demonstrated with arterial spin labeling, highlighting the potential value of perfusion magnetic resonance imaging in the clinical evaluation and follow-up of crossed-cerebellar diaschisis, and the suitability of arterial spin labeling methods for routine perfusion imaging in pediatric patients.
authors.affiliation: Department of Neuroradiology, King's College Hospital, London, United Kingdom. ruth.ogorman@kcl.ac.uk
authors.forename: Ruth L
authors.initials: RL
authors.lastname: O'Gorman
authors.forename: Ata
authors.initials: A
authors.lastname: Siddiqui
authors.forename: David C
authors.initials: DC
authors.lastname: Alsop
authors.forename: Jozef M
authors.initials: JM
authors.lastname: Jarosz
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D002544:Cerebral Infarction / Q000150:complications / Q000473:pathology*; D054022:Cerebrum / Q000473:pathology; D002648:Child; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D012720:Severity of Illness Index