Long-term outcome after neonatal hypoxic-ischaemic encephalopathy.
Outcome of full-term infants with neonatal encephalopathy of hypoxic-ischemic origin is often assessed in infancy or early childhood and data on outcome in childhood and adolescence is limited. MRI performed in the neonatal period has made a huge contribution to recognition of different patterns of injury. These different patterns of injury are related to the severity of later motor and cognitive disabilities. Long-term follow-up shows that cognitive and memory difficulties may follow even in children without motor deficits. It is therefore recommended to perform follow-up assessment into childhood in children with and without adverse neurological outcome in early infancy.
de Vries
Linda S
LS
Department of Neonatology, University Medical Centre Utrecht/Wilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands. l.s.devries@umcutrecht.nl
Jongmans
Marian J
MJ
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology; D002658:Developmental Disabilities / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000473:pathology; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011379:Prognosis