title: Acute promyelocytic leukemia during pregnancy.
abstract: OBJECTIVE
  To report our experience about a woman with acute promyelocytic leukemia (APL) during pregnancy. We focus on the obstetric treatment of our patient.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University Hospital.
  
  
  METHODS
  A 32-year-old-woman, gravida 2, para 1, at the 25th week of pregnancy with a diagnosis of APL.
  
  
  METHODS
  Multidisciplinary approach to the problem with the aim to ensure a good outcome for both the mother and the baby.
  
  
  METHODS
  Treatment of maternal malignancy and fetal outcome.
  
  
  RESULTS
  At discharge, after 2 months in hospital, the baby had no neurologic or sensitive deficiencies, and his general health was good. The mother is now undergoing the third and last consolidation step with good results, and APL is in remission.
  
  
  CONCLUSIONS
  In cases of APL during the second and third trimesters, the modern chemotherapy associated with close monitoring of maternal and fetal well-being could ensure a good outcome for both the mother and the baby.
authors.affiliation: Clinic of Obstetrics and Gynaecology, University Hospital of Udine, Udine, Italy. ganzittilaura@live.it
authors.forename: Laura
authors.initials: L
authors.lastname: Ganzitti
authors.forename: Giorgio
authors.initials: G
authors.lastname: Fachechi
authors.forename: Lorenza
authors.initials: L
authors.lastname: Driul
authors.forename: Diego
authors.initials: D
authors.lastname: Marchesoni
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003907:Dexamethasone / Q000008:administration & dosage; D005260:Female; D005323:Fetal Monitoring; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage; D007231:Infant, Newborn; D033183:Interdisciplinary Communication; D015473:Leukemia, Promyelocytic, Acute / Q000175:diagnosis* / Q000628:therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000628:therapy; D011262:Pregnancy Trimester, Second; D014212:Tretinoin / Q000008:administration & dosage
chemical_list: D014212:Tretinoin; D003907:Dexamethasone; D015255:Idarubicin