Migraine and cerebrovascular risk.
Migraine (in particular with aura) is a risk factor for cerebrovascular disease; the relative risk of stroke in migraineurs is about twofold, and increases with the coexistence of female gender, cigarette smoking and old-preparation contraceptive use. The mechanisms of the increased risk are not completely understood, and the absolute risk of stroke is low; yet, migraineurs have to be advised on how to reduce the risk for primary prevention of stroke.
Del Sette
Massimo
M
S. Andrea Hospital, La Spezia, Italy. massimo.delsette@asl5.liguria.it
D002561:Cerebrovascular Disorders / Q000150:complications*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000150:complications*; D012306:Risk; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking
D003278:Contraceptives, Oral, Hormonal
Stroke. 2004 Jul;35(7):1574-8
15143296
Headache. 2004 Jul-Aug;44(7):642-51
15209685
BMJ. 2005 Jan 8;330(7482):63
15596418
Neurology. 2008 Apr 22;70(17):1510-7
18354079
BMJ. 1999 Jan 2;318(7175):13-8
9872876
Headache. 2008 Apr;48(4):661-7
18377395
JAMA. 2006 Jul 19;296(3):283-91
16849661
Neurology. 2004 Feb 24;62(4):563-8
14981171
BMJ. 2008 Aug 07;337:a636
18687721
Stroke. 2006 Jun;37(6):1583-633
16675728
Cephalalgia. 2008 Apr;28(4):376-82
18294247
Cerebrovasc Dis. 1998 Nov-Dec;8(6):327-30
9774749
Mol Genet Metab. 2006 Jun;88(2):107-13
16403664
Stroke. 2007 Sep;38(9):2438-45
17690308
Br Med J (Clin Res Ed). 1983 Nov 12;287(6403):1442-3
6416449
Neurology. 2005 May 10;64(9):1573-7
15883318