Glial versus melanocyte cell fate choice: Schwann cell precursors as a cellular origin of melanocytes.
Melanocytes and Schwann cells are derived from the multipotent population of neural crest cells. Although both cell types were thought to be generated through completely distinct pathways and molecular processes, a recent study has revealed that these different cell types are intimately interconnected far beyond previously postulated limits in that they share a common post-neural crest progenitor, i.e. the Schwann cell precursor. This finding raises interesting questions about the lineage relationships of hitherto unrelated cell types such as melanocytes and Schwann cells, and may provide clinical insights into mechanisms of pigmentation disorders and for cancer involving Schwann cells and melanocytes.
Adameyko
Igor
I
Unit of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles väg 1-A1-plan2, 171 77, Stockholm, Sweden. igor.adameyko@ki.se
Lallemend
Francois
F
D000818:Animals; D005075:Biological Evolution; D002454:Cell Differentiation; D002465:Cell Movement; D008544:Melanocytes / Q000166:cytology*; D051379:Mice; D009457:Neuroglia / Q000166:cytology*; D010859:Pigmentation Disorders / Q000473:pathology; D012583:Schwann Cells / Q000166:cytology*; D013234:Stem Cells / Q000166:cytology*; D015027:Zebrafish / Q000254:growth & development
Melanoma Res. 2004 Apr;14(2):159-63
15057048
Nature. 1999 Dec 2;402(6761):496-501
10591209
Neuron. 1994 Mar;12(3):509-27
8155318
Cell. 1994 May 6;77(3):349-60
7910115
Curr Opin Cell Biol. 2006 Dec;18(6):698-703
17030122
Annu Rev Genet. 2004;38:365-411
15568981
Development. 1993 Jun;118(2):363-76
7693414
Cancer Invest. 2008 Jun;26(5):516-34
18568775
Development. 2000 Jul;127(13):2811-21
10851127
Cell. 2009 Oct 16;139(2):366-79
19837037
Bioessays. 2008 Jun;30(6):530-41
18478530
Pigment Cell Melanoma Res. 2010 Feb;23(1):144-6
19793384
Q Rev Biol. 1983 Mar;58(1):1-28
6346380
J Invest Dermatol. 1995 Sep;105(3):322-8
7545201
Development. 2002 Jul;129(14):3349-57
12091305
Pigment Cell Res. 2005 Feb;18(1):13-24
15649148
Nat Neurosci. 2003 Nov;6(11):1186-93
14555954
Dev Biol. 2001 Dec 15;240(2):301-14
11784065
Development. 2010 Mar;137(5):705-14
20147375
J Biol Chem. 2000 Dec 1;275(48):37978-83
10973953
Cell. 2008 Jun 27;133(7):1162-74
18585351
Dev Biol. 1973 Jan;30(1):217-22
4121410
Genes Dev. 1999 Oct 1;13(19):2538-48
10521398
Cancer Cell. 2008 Feb;13(2):117-28
18242512
Prog Clin Biol Res. 1988;256:35-48
3368494
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4495-500
15070746
Semin Cell Dev Biol. 2009 Feb;20(1):117-24
18950723
Development. 1996 Apr;122(4):1207-14
8620847
Nat Rev Mol Cell Biol. 2008 Jul;9(7):557-68
18523435
Development. 2004 Oct;131(19):4637-50
15358668
Development. 2001 Apr;128(8):1467-79
11262245
Genes Dev. 2003 Jun 1;17(11):1380-91
12782656
J Invest Dermatol. 2004 Nov;123(5):924-9
15482481
Dev Biol. 1995 Oct;171(2):317-29
7556916
Cell Stem Cell. 2009 May 8;4(5):453-63
19427294
Development. 1996 Dec;122(12):3911-9
9012511
Neuron. 1995 Sep;15(3):585-96
7546738
Nature. 2003 Jan 16;421(6920):264-7
12529642
J Neurosci. 1995 Feb;15(2):1329-40
7869101
Cell. 1994 Dec 30;79(7):1257-66
8001158
J Laryngol Otol. 2003 Jul;117(7):584-7
12901822
PLoS Genet. 2009 Nov;5(11):e1000744
19956727
Trends Mol Med. 2006 Sep;12(9):406-14
16899407
J Neurosci. 2002 Nov 15;22(22):9831-40
12427839
EMBO J. 1991 Aug;10(8):2111-8
1712289
Mech Dev. 2001 Mar;101(1-2):47-59
11231058
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14214-9
9826680
J Cell Biol. 2000 Mar 6;148(5):1035-46
10704452
Development. 1998 Aug;125(15):2915-23
9655813
Australas J Dermatol. 2009 Nov;50(4):294-6
19916976
Oncogene. 2003 May 19;22(20):3016-23
12789276
Pigment Cell Res. 1998 Feb;11(1):38-44
9523334
Development. 1997 Jun;124(12):2377-86
9199364
EMBO J. 1991 May;10(5):1135-47
2022185
Neuron. 2005 Sep 1;47(5):681-94
16129398
Mol Cell Biol. 2000 May;20(9):3198-209
10757804
Dev Biol. 2003 Jul 1;259(1):162-75
12812796
Am J Hum Genet. 2007 Aug;81(2):243-51
17668375
Genes Dev. 2001 Jan 1;15(1):66-78
11156606
J Eur Acad Dermatol Venereol. 2010 May;24(5):611-2
19793152
J Biol Chem. 2004 Oct 1;279(40):41911-7
15277526
Development. 1989 Aug;106(4):809-16
2562671
Dev Biol. 2000 Nov 15;227(2):545-57
11071773
Cancer Cell. 2008 Feb;13(2):105-16
18242511
Dev Biol. 1997 Dec 1;192(1):99-107
9405100
Dev Biol. 1991 Aug;146(2):312-24
1713863
Int J Dev Biol. 2005;49(2-3):151-9
15906228
Nat Rev Neurosci. 2005 Sep;6(9):671-82
16136171
Dev Biol. 1977 Oct 1;60(1):226-37
561724
Dev Biol. 2001 Sep 15;237(2):245-57
11543611
Proc Natl Acad Sci U S A. 1979 Apr;76(4):1843-7
287025
J Exp Zool B Mol Dev Evol. 2006 Sep 15;306(5):470-80
16619245
PLoS Genet. 2009 Jul;5(7):e1000544
19578401
Dev Biol. 2002 Apr 1;244(1):199-214
11900468
Development. 1993 Aug;118(4):1313-26
8269857
Development. 2008 Aug;135(15):2603-14
18508863
Neuron. 1999 Jun;23(2):273-83
10399934
Anat Rec. 1966 Oct;156(2):143-55
5969670
Curr Biol. 2005 Mar 29;15(6):513-24
15797019
Development. 2001 Oct;128(20):3949-61
11641219
J Biomed Sci. 2002 Nov-Dec;9(6 Pt 2):564-73
12432222
Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9229-34
8799183
Dev Biol. 1986 Dec;118(2):392-8
3792615
Nature. 1998 Nov 26;396(6709):370-3
9845073
J Cell Biol. 2006 Dec 18;175(6):1005-15
17158956
J Biol Chem. 1996 Sep 20;271(38):23126-33
8798505
Bioessays. 2000 Nov;22(11):987-96
11056475
Development. 1997 Jan;124(1):65-77
9006068
Semin Cell Dev Biol. 2007 Aug;18(4):481-91
17509911
Development. 1996 Oct;122(10):3023-33
8898216
Cell Growth Differ. 1999 Jul;10(7):525-36
10437920
Cell. 1994 Dec 30;79(7):1277-85
8001160
Dev Biol. 1963 Jun;6:279-310
14000137
Melanoma Res. 2008 Dec;18(6):438-42
19011514
Pigment Cell Res. 2000 Jun;13(3):172-8
10885676
Mech Dev. 2002 Oct;118(1-2):139-46
12351177
Nat Rev Neurosci. 2006 Feb;7(2):93-102
16429119
Nature. 1997 Oct 16;389(6652):725-30
9338783
Genes Dev. 2000 Jan 15;14(2):158-62
10652270
Dev Biol. 2001 May 1;233(1):22-37
11319855
Cancer Cell. 2008 Feb;13(2):129-40
18242513
Development. 1990 Apr;108(4):605-12
2387238
Development. 2004 Nov;131(22):5599-612
15496445
Curr Opin Cell Biol. 2008 Apr;20(2):201-7
18291635
Development. 2000 Dec;127(24):5379-89
11076759
Mol Cancer. 2006 Sep 10;5:36
16961930
Nature. 2007 Nov 15;450(7168):415-9
17928865
J Biol Chem. 2000 Oct 6;275(40):30757-60
10938265
Anat Rec. 1947 Dec;99(4):648
18935453
Development. 2007 Jul;134(13):2435-47
17537790
Genes Dev. 2002 Oct 15;16(20):2650-61
12381664
J Biol Chem. 2000 May 12;275(19):14013-6
10747853
Neuron. 2003 Apr 10;38(1):17-31
12691661
Trends Neurosci. 2003 Jan;26(1):40-5
12495862
Nat Neurosci. 2009 Jul;12(7):839-47
19525946
Glia. 2008 Nov 1;56(14):1481-90
18803317
Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7882-7
10884419
Dev Biol. 2009 Aug 15;332(2):408-17
19527705
J Neurosci. 1996 Oct 1;16(19):6107-18
8815893
Nat Genet. 1996 Sep;14(1):50-4
8782819
Neuroradiology. 2003 Sep;45(9):618-25
12898075
J Comp Neurol. 1997 Aug 11;384(4):483-500
9259485
Development. 1995 Mar;121(3):731-42
7536655
Development. 2006 Sep;133(18):3563-73
16914496
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5229-33
12702775
Pigment Cell Res. 2004 Oct;17(5):461-70
15357832
Development. 2009 Jun;136(11):1849-58
19403660
J Neurosci. 1999 May 15;19(10):3847-59
10234017
Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1431-5
7877996
Dev Biol. 2006 Dec 15;300(2):656-69
17052705
Nature. 2004 Oct 7;431(7009):696-9
15470430
Pigment Cell Melanoma Res. 2008 Dec;21(6):598-610
19067969
Pigment Cell Res. 1993 Oct;6(5):336-47
8302772
Development. 2007 Sep;134(18):3271-81
17699610
Nature. 1997 Oct 30;389(6654):966-70
9353119
Cell. 2000 May 26;101(5):499-510
10850492
J Cell Biol. 2002 Dec 9;159(5):867-80
12473692
Development. 2000 Sep;127(17):3715-24
10934016
Science. 2002 May 31;296(5573):1644-6
12040179
Leukemia. 1998 Feb;12(2):207-12
9519783
Ann Thorac Surg. 2009 Oct;88(4):e42-3
19766777
Dev Biol. 1977 Oct 1;60(1):217-25
911400
Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9081-5
16757562
Br J Dermatol. 1977 Sep;97(3):255-61
921895
Development. 2001 Nov;128(21):4127-38
11684651