title: Optimal cutoff value of contralateral testicular size for prediction of absent testis in Japanese boys with nonpalpable testis.
abstract: OBJECTIVE
  To investigate the accuracy of contralateral testicular hypertrophy in Japanese boys with a nonpalpable testis and to determine the optimal cutoff value of the contralateral testicular size to predict the absence of the testis.
  
  
  METHODS
  From December 2003 to November 2009, we evaluated 55 boys <60 months old (mean age 19.4) with a unilateral nonpalpable testis and compared their findings with those of a control group. The control group included 20 age-matched boys with 40 testes. The nonpalpable status of the testes was diagnosed by physical examination, and the contralateral testis was measured with calipers before surgery. A sensitivity and specificity analysis were performed using computer software.
  
  
  RESULTS
  At surgery, the testis was found in 22 of the 55 boys and was absent in 33. Of the 33 boys with an absent testis, 4 had a blind-ending vessel and 29 had an atrophic cord and testicular nubbin in the canal or scrotum. The mean contralateral testicular length and volume in the boys with an absent testis was 22.4 mm and 2.20 cm(3) compared with 16.6 mm and 1.10 cm(3) in the boys with the testis present and 16.6 mm and 1.18 cm(3) in the controls, respectively (P < .01). The predictive accuracy, sensitivity, and specificity for an absent testis was 87.3%, 81.8%, and 95.5% for the length and 85.5%, 84.8%, and 86.4% for the volume, respectively, at the optimal cutoff value of 21 mm in length and 1.6 cm(3) in volume.
  
  
  CONCLUSIONS
  Our data have shown that contralateral testicular hypertrophy strongly indicates an absent testis in Japanese boys. The optimal cutoff for contralateral testicular hypertrophy with calipers was 21 mm and 1.6 cm(3). This result has provided valuable information for preoperative counseling and treatment planning.
authors.affiliation: Department of Nephrourology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shibata
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kojima
authors.forename: Kentaro
authors.initials: K
authors.lastname: Mizuno
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nakane
authors.forename: Toshiki
authors.initials: T
authors.lastname: Kato
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kamisawa
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kohri
authors.forename: Yutaro
authors.initials: Y
authors.lastname: Hayashi
mesh_terms: D002675:Child, Preschool; D006801:Humans; D006984:Hypertrophy; D007564:Japan; D008297:Male; D009929:Organ Size; D010173:Palpation; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013737:Testis / Q000002:abnormalities* / Q000473:pathology*