title: Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate.
abstract: We report the synthesis and in vitro evaluation of folate receptor-targeted nanoconjugate that releases its therapeutic payload via a photochemical mechanism.
authors.affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Medical School, Ann Arbor, MI 48109, USA. skchoi@umich.edu
authors.forename: Seok Ki
authors.initials: SK
authors.lastname: Choi
authors.forename: Thommey
authors.initials: T
authors.lastname: Thomas
authors.forename: Ming-Hsin
authors.initials: MH
authors.lastname: Li
authors.forename: Alina
authors.initials: A
authors.lastname: Kotlyar
authors.forename: Ankur
authors.initials: A
authors.lastname: Desai
authors.forename: James R
authors.initials: JR
authors.lastname: Baker
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D002352:Carrier Proteins / Q000737:chemistry* / Q000378:metabolism; D050091:Dendrimers / Q000138:chemical synthesis / Q000737:chemistry*; D004317:Doxorubicin / Q000008:administration & dosage*; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry; D058973:Folate Receptors, GPI-Anchored; D005492:Folic Acid / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D010782:Photolysis; D011956:Receptors, Cell Surface / Q000737:chemistry* / Q000378:metabolism; D014466:Ultraviolet Rays
chemical_list: D000903:Antibiotics, Antineoplastic; D002352:Carrier Proteins; D050091:Dendrimers; D004337:Drug Carriers; D058973:Folate Receptors, GPI-Anchored; C104700:PAMAM Starburst; D011956:Receptors, Cell Surface; D004317:Doxorubicin; D005492:Folic Acid
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