title: Long-term survival outcomes of laparoscopically assisted radical hysterectomy in treating early-stage cervical cancer.
abstract: OBJECTIVE
  The objective of the study was to determine the long-term disease-free and overall survival outcomes of laparoscopic treatment of early-stage cervical cancer.
  
  
  METHODS
  This was a longitudinal study of prospectively registered patients of cervical cancer undergoing laparoscopic surgery from June 1994 to December 2005.
  
  
  RESULTS
  A total of 139 patients were included, in which 60 patients were in International Federation of Gynecology and Obstetrics stage IA, 76 in IB, and 3 in IIA. Mean operation time was 231.1 +/- 6.1 minutes. Median number of pelvic lymph node retrieval was 16. Major intraoperative complications included 1 great vessel injury, 1 ureteral injury, 1 colon injury, and 6 cystotomies. In a median follow-up of 92.1 months, the mean +/- SEM cumulative disease-free and overall survival rates were 91.01% +/- 2.77% and 92.78% +/- 3.06%, respectively.
  
  
  CONCLUSIONS
  The laparoscopic approach has favorable long-term survival outcomes and perioperative morbidity. With the advantage of minimal invasiveness, laparoscopic treatment by experienced surgeons is an ideal alternative for early-stage cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Tao-Yuan, Taiwan, Republic of China.
authors.forename: Chyi-Long
authors.initials: CL
authors.lastname: Lee
authors.forename: Kai-Yun
authors.initials: KY
authors.lastname: Wu
authors.forename: Kuan-Gen
authors.initials: KG
authors.lastname: Huang
authors.forename: Pei-Shan
authors.initials: PS
authors.lastname: Lee
authors.forename: Chih-Feng
authors.initials: CF
authors.lastname: Yen
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002681:China; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000379:methods* / Q000401:mortality; D015907:Hysteroscopy / Q000379:methods; D007150:Immunohistochemistry; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D008137:Longitudinal Studies; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality / Q000503:physiopathology; D011446:Prospective Studies; D012042:Registries; D018570:Risk Assessment; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*