title: Evaluation of eight cases of confirmed Bordetella bronchiseptica infection and colonization over a 15-year period.
abstract: We describe eight human cases of Bordetella bronchiseptica infection and colonization over a 15-year period. Amongst the eight patients, seven had significant underlying disease. Cat exposure was documented in three cases. Symptoms ranged from asymptomatic carriage to severe pneumonia. We could not identify a homogeneous pattern of clinical disease among symptomatic patients. Although B. bronchiseptica infection remains a rare clinical condition among humans, it should be considered as potentially pathogenic when found in airways of immunocompromised patients.
authors.affiliation: Division of Infectious Diseases and Clinical Microbiology Laboratory, University of Geneva Hospitals and Medical School, Geneva, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Wernli
authors.forename: S
authors.initials: S
authors.lastname: Emonet
authors.forename: J
authors.initials: J
authors.lastname: Schrenzel
authors.forename: S
authors.initials: S
authors.lastname: Harbarth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001885:Bordetella Infections / Q000382:microbiology* / Q000473:pathology; D016950:Bordetella bronchiseptica / Q000302:isolation & purification*; D002353:Carrier State / Q000382:microbiology* / Q000473:pathology; D002415:Cats; D005260:Female; D006801:Humans; D008297:Male; D057805:Pets; D018410:Pneumonia, Bacterial / Q000382:microbiology* / Q000473:pathology; D055815:Young Adult; D015047:Zoonoses / Q000635:transmission