[Acute hyperglycemia and reperfusion therapy in stroke patients].
Current acute therapies for ischemic stroke are limited. Only a small proportion of stroke patients are eligible to receive reperfusion therapy. Acute hyperglycemia has a deleterious effect in stroke patients by accelerating ischemic brain damage. The complex relationship between hyperglycemia and stroke is discussed. In tPA-treated patients, the acute but not chronic hyperglycemic state may hamper fibrinolytic process, delaying reperfusion of ischemic penumbra. Early measures to reduce hyperglycemia may favor early recanalization.
Krajícková
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Neurologická klinika Lékarské fakulty UK a FN Hradec Králové. krajickova@fnhk.cz
D000208:Acute Disease; D002560:Cerebrovascular Circulation; D006801:Humans; D006943:Hyperglycemia / Q000150:complications*; D020521:Stroke / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D015912:Thrombolytic Therapy