Treatment of skin cancers in epidermolysis bullosa.
Squamous cell carcinomas (SCCs) are highly aggressive in patients with epidermolysis bullosa (EB). Non-ultraviolet-related SCCs are the leading cause of death in patients with recessive dystrophic EB, particularly recessive dystrophic EB-generalized severe subtype (RDEB-GS). The mechanism of SCC development in patients with RDEB continues to be investigated and several theories have been reported in the literature.
Venugopal
Supriya S
SS
Department of Dermatology, St George Hospital, University of New South Wales, Kogarah, Sydney, NSW, Australia.
Murrell
Dédée F
DF
D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D004820:Epidermolysis Bullosa / Q000150:complications* / Q000473:pathology; D006801:Humans; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy*