title: Contrast-enhanced MRI of the small bowel in Crohn's disease.
abstract: Recently, magnetic resonance imaging has emerged as a valuable tool in evaluation of small bowel Crohn's disease. MRI provides several advantages to other imaging modalities, including the lack of ionizing radiation, multiplanar capability, and functional information. Intravenous contrast administration is a routine portion of MR enterography protocol, and aids in detection of disease extent, extramural complications such as fistula and abscess, and assessment of activity. Additionally, promising techniques such as dynamic contrast-enhanced MRI may provide quantitative measures to assess bowel perfusion, which may enhance evaluation of disease activity. This article will provide an overview of the technical aspects of contrast-enhanced MR enterography, describe common pathologic findings involving the small bowel in Crohn's disease, summarize its role in determination of activity with an emphasis on endoscopic and histologic correlation, and compare its efficacy with other imaging modalities.
authors.affiliation: Department of Radiology, University of Chicago, Chicago, IL, USA. jkoommen1@gmail.com
authors.forename: Jacob
authors.initials: J
authors.lastname: Oommen
authors.forename: Aytekin
authors.initials: A
authors.lastname: Oto
mesh_terms: D003287:Contrast Media; D003424:Crohn Disease / Q000473:pathology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D007421:Intestine, Small; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media