Applications of novel drug delivery system for herbal formulations.
Over the past several years, great advances have been made on development of novel drug delivery systems (NDDS) for plant actives and extracts. The variety of novel herbal formulations like polymeric nanoparticles, nanocapsules, liposomes, phytosomes, nanoemulsions, microsphere, transferosomes, and ethosomes has been reported using bioactive and plant extracts. The novel formulations are reported to have remarkable advantages over conventional formulations of plant actives and extracts which include enhancement of solubility, bioavailability, protection from toxicity, enhancement of pharmacological activity, enhancement of stability, improved tissue macrophages distribution, sustained delivery, and protection from physical and chemical degradation. The present review highlights the current status of the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, size, entrapment efficiency, route of administration, biological activity and applications of novel formulations.
Ajazuddin
University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, C.G., 492010, India.
Saraf
S
S
D002626:Chemistry, Pharmaceutical; D004304:Dosage Forms; D004333:Drug Administration Routes; D016503:Drug Delivery Systems; D006801:Humans; D008517:Phytotherapy; D028321:Plant Preparations / Q000008:administration & dosage*
D004304:Dosage Forms; D028321:Plant Preparations