title: Extrastriate body area underlies aesthetic evaluation of body stimuli.
abstract: Humans appear to be the only animals to have developed the practice and culture of art. This practice presumably relies on special processing circuits within the human brain associated with a distinct subjective experience, termed aesthetic experience, and preferentially evoked by artistic stimuli. We assume that positive or negative aesthetic judgments are an important function of neuroaesthetic circuits. The localisation of these circuits in the brain remains unclear, though neuroimaging studies have suggested several possible neural correlates of aesthetic preference. We applied repetitive transcranial magnetic stimulation (rTMS) over candidate brain areas to disrupt aesthetic processing while healthy volunteers made aesthetic preference judgments between pairs of dance postures, or control non-body stimuli. Based on evidence from visual body perception studies, we targeted the ventral premotor cortex (vPMC) and extrastriate body area (EBA), in the left and right hemispheres. rTMS over EBA reduced aesthetic sensitivity for body stimuli relative to rTMS over vPMC, while no such difference was found for non-body stimuli. We interpret our results within the framework of dual routes for visual body processing. rTMS over either EBA or vPMC reduced the contributions of the stimulated area to body processing, leaving processing more reliant on the unaffected route. Disruption of EBA reduces the local processing of the stimuli and reduced observers' aesthetic sensitivity. Conversely, disruption of the global route via vPMC increased the relative contribution of the local route via EBA and thus increased aesthetic sensitivity. In this way, we suggest a complementary contribution of both local and global routes to aesthetic processing.
authors.affiliation: Department of Psychology, City University London, Northampton Square, London, EC1V 0HB, UK. b.calvo@city.ac.uk
authors.forename: B
authors.initials: B
authors.lastname: Calvo-Merino
authors.forename: C
authors.initials: C
authors.lastname: Urgesi
authors.forename: G
authors.initials: G
authors.lastname: Orgs
authors.forename: S M
authors.initials: SM
authors.lastname: Aglioti
authors.forename: P
authors.initials: P
authors.lastname: Haggard
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001828:Body Image; D001921:Brain / Q000502:physiology*; D004954:Esthetics; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007600:Judgment / Q000502:physiology; D008297:Male; D009044:Motor Cortex / Q000502:physiology; D009483:Neuropsychological Tests; D009778:Occipital Lobe / Q000502:physiology*; D010775:Photic Stimulation; D050781:Transcranial Magnetic Stimulation; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
references.citation: J Exp Psychol Hum Percept Perform. 1995 Apr;21(2):334-43
references.pmid: 7714475
references.citation: J Neurophysiol. 2005 Jan;93(1):603-8
references.pmid: 15295012
references.citation: Neuroreport. 2004 Apr 9;15(5):893-7
references.pmid: 15073538
references.citation: Curr Biol. 2007 Aug 21;17(16):R724-32
references.pmid: 17714666
references.citation: Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6321-5
references.pmid: 15079079
references.citation: Eur J Neurosci. 2008 Jun;27(12):3380-4
references.pmid: 18598273
references.citation: Neuroimage. 2007 Jul 1;36(3):1004-14
references.pmid: 17478105
references.citation: Perception. 2008;37(8):1187-96
references.pmid: 18853555
references.citation: Spat Vis. 2008;21(3-5):379-96
references.pmid: 18534110
references.citation: Br J Psychol. 2004 Nov;95(Pt 4):489-508
references.pmid: 15527534
references.citation: Exp Brain Res. 1992;91(1):176-80
references.pmid: 1301372
references.citation: Neuron. 2003 Oct 30;40(3):655-64
references.pmid: 14642287
references.citation: Curr Biol. 2006 Oct 10;16(19):1905-10
references.pmid: 17027486
references.citation: Brain. 1994 Jun;117 ( Pt 3):607-36
references.pmid: 8032869
references.citation: Neuron. 2008 Oct 23;60(2):235-46
references.pmid: 18957216
references.citation: Curr Biol. 2004 Dec 14;14(23):2130-4
references.pmid: 15589156
references.citation: Nat Rev Neurosci. 2007 Aug;8(8):636-48
references.pmid: 17643089
references.citation: Psychol Sci. 2003 Jul;14(4):302-8
references.pmid: 12807401
references.citation: J Neurosci. 2007 Jul 25;27(30):8023-30
references.pmid: 17652592
references.citation: Conscious Cogn. 2008 Sep;17(3):911-22
references.pmid: 18207423
references.citation: Neurophysiol Clin. 2008 Jun;38(3):189-95
references.pmid: 18539253
references.citation: Psychol Rep. 2004 Jun;94(3 Pt 2):1253-60
references.pmid: 15362400
references.citation: Br J Psychol. 2005 Nov;96(Pt 4):493-503
references.pmid: 16248938
references.citation: Neuroreport. 2004 Oct 25;15(15):2407-10
references.pmid: 15640765
references.citation: J Neurophysiol. 2004 Apr;91(4):1699-705
references.pmid: 15010496
references.citation: Neuroimage. 2006 Jan 1;29(1):276-85
references.pmid: 16087351
references.citation: PLoS One. 2007 Nov 21;2(11):e1201
references.pmid: 18030335
references.citation: J Exp Psychol Hum Percept Perform. 2005 Dec;31(6):1234-46
references.pmid: 16366786
references.citation: Neuropsychologia. 1999 Feb;37(2):191-8
references.pmid: 10080376
references.citation: Neuron. 2004 Oct 14;44(2):379-87
references.pmid: 15473974
references.citation: Neuropsychologia. 2007 Jun 11;45(10):2201-15
references.pmid: 17448507
references.citation: J Neurophysiol. 2007 Sep;98(3):1626-33
references.pmid: 17596425
references.citation: Neuron. 2004 Apr 22;42(2):335-46
references.pmid: 15091347
references.citation: Nat Neurosci. 2004 May;7(5):542-8
references.pmid: 15107859
references.citation: Science. 2001 Sep 28;293(5539):2470-3
references.pmid: 11577239
references.citation: Cortex. 1975 Sep;11(3):230-8
references.pmid: 1204363
references.citation: Nature. 2005 Dec 22;438(7071):1148-50
references.pmid: 16372008
references.citation: Electroencephalogr Clin Neurophysiol. 1998 Jan;108(1):1-16
references.pmid: 9474057
references.citation: Cereb Cortex. 2005 Aug;15(8):1243-9
references.pmid: 15616133