The Streptococcus milleri population of a cystic fibrosis clinic reveals patient specificity and intraspecies diversity.
The genetic relatedness of Streptococcus milleri group isolates from the airways of cystic fibrosis patients was determined by using pulsed-field gel electrophoresis. This study reveals no evidence for patient-to-patient transmission in our patient population; however, within individual patients, complex inter- and intraspecies diversity and dynamics can be observed.
Sibley
Christopher D
CD
Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.
Sibley
Kristen A
KA
Leong
Tara A
TA
Grinwis
Margot E
ME
Parkins
Michael D
MD
Rabin
Harvey R
HR
Surette
Michael G
MG
D016000:Cluster Analysis; D015331:Cohort Studies; D003428:Cross Infection / Q000150:complications / Q000382:microbiology; D003550:Cystic Fibrosis / Q000150:complications / Q000382:microbiology; D016172:DNA Fingerprinting; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008168:Lung / Q000382:microbiology; D013045:Species Specificity; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology; D034364:Streptococcus milleri Group / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification
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