[Integrin and repair following nervous system injury].
OBJECTIVE
To review the role of integrin in nervous system injury and its repair, and to analyze the possible mechanisms.


METHODS
Recent literature concerning integrin and its role in nervous system injury was reviewed and analyzed.


RESULTS
Integrin and its related signalling pathway were involved in nervous system injury, especially hypoxic-ischemic nervous injury, and their repair processes.


CONCLUSIONS
Intervention of integrin signalling pathway would be a potential strategy to treat nervous system injury, especially hypoxic-ischemic nervous injury.
Tang
Binzhi
B
Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R. China.
Qu
Yi
Y
Mu
Dezhi
D
D016023:Integrins / Q000378:metabolism; D015398:Signal Transduction; D020196:Trauma, Nervous System / Q000378:metabolism* / Q000628:therapy
D016023:Integrins