title: Isolated myeloid sarcoma of the gastrointestinal tract.
abstract: Myeloid sarcoma (MS) is a rare disease that presents as an extramedullary tumor of myeloid cells. Most patients subsequently develop acute myelogenous leukemia (AML), and their prognosis is poor. Here, we report the case of a 28-year-old woman with a primary isolated myeloid sarcoma which originated in the gastrointestinal (GI) tract. Two months after initial presentation, bone marrow tests led to a diagnosis of AML. This case is noteworthy because GI tract infiltration with leukemic cells is very rare, and it is even more rare as an occurrence preceding the development of systemic leukemia.
authors.affiliation: Institute of Hematology, Clinical Center Serbia, Belgrade. tweety@scnet.rs
authors.forename: Darko
authors.initials: D
authors.lastname: Antic
authors.forename: Ivo
authors.initials: I
authors.lastname: Elezovic
authors.forename: Andrija
authors.initials: A
authors.lastname: Bogdanovic
authors.forename: Nada Suvajdzic
authors.initials: NS
authors.lastname: Vukovic
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Pavlovic
authors.forename: Maja Perunicic
authors.initials: MP
authors.lastname: Jovanovic
authors.forename: Ljubomir
authors.initials: L
authors.lastname: Jakovic
authors.forename: Nada
authors.initials: N
authors.lastname: Kraguljac
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D018450:Disease Progression; D004386:Duodenum / Q000473:pathology; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007421:Intestine, Small / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000473:pathology*; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000473:pathology*; D012720:Severity of Illness Index; D016312:Treatment Refusal