Epigenetic markers in rectal cancer.
DNA methylation changes in rectal cancer may serve as a new screening marker and a tool for monitoring recurrence. Importantly, these changes may also function as a predictive marker to allow appropriate exclusion of (neo)adjuvant therapies in patients at low risk for disease recurrence, sparing them from potential treatment-related morbidities.
Xu
Lei
L
Steele Laboratory, Massachusetts General Hospital, Boston, Massachusetts, USA.
Czito
Brian G
BG
Willett
Christopher G
CG
D014408:Biomarkers, Tumor / Q000235:genetics*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D006801:Humans; D012004:Rectal Neoplasms / Q000235:genetics*
D014408:Biomarkers, Tumor