title: Compact instrument for fluorescence image-guided surgery.
abstract: Fluorescence image-guided surgery (FIGS) is an emerging technique in oncology, neurology, and cardiology. To adapt intraoperative imaging for various surgical applications, increasingly flexible and compact FIGS instruments are necessary. We present a compact, portable FIGS system and demonstrate its use in cardiovascular mapping in a preclinical model of myocardial ischemia. Our system uses fiber optic delivery of laser diode excitation, custom optics with high collection efficiency, and compact consumer-grade cameras as a low-cost and compact alternative to open surgical FIGS systems. Dramatic size and weight reduction increases flexibility and access, and allows for handheld use or unobtrusive positioning over the surgical field.
authors.affiliation: GE Global Research, 1 Research Circle, Niskayuna, New York 12309, USA.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Wang
authors.forename: Srabani
authors.initials: S
authors.lastname: Bhaumik
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.forename: V Paul
authors.initials: VP
authors.lastname: Staudinger
authors.forename: Siavash
authors.initials: S
authors.lastname: Yazdanfar
mesh_terms: D000818:Animals; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D007089:Image Enhancement / Q000295:instrumentation*; D008297:Male; D008856:Microscopy, Fluorescence / Q000295:instrumentation*; D008904:Miniaturization; D017202:Myocardial Ischemia / Q000473:pathology* / Q000601:surgery*; D051381:Rats; D017208:Rats, Wistar; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted / Q000295:instrumentation*