[The influence of ion metal on flavonoid radioprotection activity towards yeast cells].
Influence of ion Mn2+ and Fe2+ on ability of flavonoids intercept free radical and reveal radioprotection activity towards yeast cells was investigated. In work have been used flavonols quercetin, rutin and anthocyanins allocated of flowers Hibiscus. As a measure of radiating damage of cages of yeast the exit of ions K+ served. It is shown that Fe2+ ions essentially reduce protection activity flavonoids, and the ions of manganese showing protection properties, at presence anthocyanins sensibilization radiation damage.
Suvorova
A A
AA
Fenin
A A
AA
D000872:Anthocyanins / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology*; D004336:Drug Antagonism; D005419:Flavonoids / Q000494:pharmacology*; D035264:Flowers / Q000737:chemistry; D005609:Free Radicals / Q000037:antagonists & inhibitors; D031584:Hibiscus / Q000737:chemistry; D007501:Iron / Q000494:pharmacology*; D008345:Manganese / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism; D011794:Quercetin / Q000494:pharmacology; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D012431:Rutin / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism
D000872:Anthocyanins; D000975:Antioxidants; D005419:Flavonoids; D005609:Free Radicals; D011837:Radiation-Protective Agents; D008345:Manganese; D012431:Rutin; D011794:Quercetin; D007501:Iron; D011188:Potassium