Transition-metal-catalyzed immobilization of organic functional groups onto solid supports through vinylsilane coupling reactions.
A novel and efficient grafting method for covalent bonding of functional organic molecules to silica or glass surfaces has been developed. The protocol employs transition-metal-catalyzed reactions of vinylsilanes with surface hydroxyl groups. Dimethyldivinylsilane can be used in this procedure as a linker in which one vinyl group is used for direct C-C bond formation with a functional organic molecule and the other is employed to immobilize the alkylsilyl group onto the hydroxyl surface of the solid support.
Park
Jung-Woo
JW
Department of Chemistry and Center for Bioactive Molecular Hybrids, Yonsei University, Seoul 120-749, Korea.
Jun
Chul-Ho
CH
D002384:Catalysis; D005898:Glass / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D028561:Transition Elements / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
D012821:Silanes; D028561:Transition Elements; D014753:Vinyl Compounds; C476909:vinylsilane; D012822:Silicon Dioxide