Enantioselective formal synthesis of eurylene: synthesis of the cis- and trans-THF fragments using oxidative cyclization.
A formal synthesis of eurylene is described, where both cis- and trans-THF-containing fragments were prepared using diastereo- and chemoselective permanganate-mediated oxidative monocyclizations of trienes.
Sheikh
Nadeem S
NS
The School of Chemistry, The University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
Bataille
Carole J
CJ
Luker
Tim J
TJ
Brown
Richard C D
RC
D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D005663:Furans; C493363:eurylene