Siderophore-mediated iron acquisition in Bacillus anthracis and related strains.
Recent observations have shed light on some of the endogenous iron-acquisition mechanisms of members of the Bacillus cereus sensu lato group. In particular, pathogens in the B. cereus group use siderophores with both unique chemical structures and biological roles. This review will focus on recent discoveries in siderophore biosynthesis and biology in this group, which contains numerous human pathogens, most notably the causative agent of anthrax, Bacillus anthracis.
Hotta
Kinya
K
Department of Biological Sciences, National University of Singapore, Singapore.
Kim
Chu-Young
CY
Department of Biological Sciences, National University of Singapore, Singapore.
Fox
David T
DT
Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Koppisch
Andrew T
AT
Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
D000818:Animals; D000881:Anthrax / Q000378:metabolism / Q000382:microbiology; D001408:Bacillus anthracis / Q000235:genetics / Q000378:metabolism*; D001692:Biological Transport; D006801:Humans; D007501:Iron / Q000378:metabolism*; D017262:Siderophores / Q000378:metabolism*
D017262:Siderophores; D007501:Iron