Prostate cancer diagnosis.
Prostate cancer is the fourth most common malignancy diagnosed in Missouri. The diagnosis may be clinically suspected based on an elevated serum prostate specific antigen (PSA) and/or digital rectal examination abnormality. Clinical symptoms are usually a manifestation of more advanced disease. The diagnosis is typically established by histopathologic examination of needle biopsy tissue. This article reviews clinical and pathological approaches to prostate cancer diagnosis, with a focus on clinically localized disease and needle biopsy diagnosis.
Humphrey
Peter A
PA
Washington University School of Medicine in St. Louis, USA. humphrey@path.wustl.edu
Andriole
Gerald L
GL
D014408:Biomarkers, Tumor / Q000097:blood; D001707:Biopsy, Needle; D051517:Digital Rectal Examination; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010338:Pathology, Clinical / Q000379:methods; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen
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