Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging.
A paramagnetic manganese complex of a fluorescein-based probe affords a dual-modality zinc sensor featuring an improved fluorescence dynamic range and an MRI readout.
You
Youngmin
Y
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Tomat
Elisa
E
Hwang
Kevin
K
Atanasijevic
Tatjana
T
Nam
Wonwoo
W
Jasanoff
Alan P
AP
Lippard
Stephen J
SJ
D005452:Fluoresceins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008345:Manganese / Q000737:chemistry*; D008856:Microscopy, Fluorescence / Q000379:methods*; D015032:Zinc / Q000032:analysis*
D005452:Fluoresceins; D005456:Fluorescent Dyes; D008345:Manganese; D015032:Zinc; C501987:zinpyr-1
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