Kinetic resolution of trans-cycloalkane-1,2-diols via Steglich esterification.
We describe the efficient and highly enantioselective kinetic resolution of trans-cycloalkane-1,2-diols utilizing an enantioselective Steglich reaction with a variety of carboxylic acids that form the corresponding anhydrides in situ.
Hrdina
Radim
R
Institute of Organic Chemistry, Justus-Liebig University, Heinrich-Buff-Ring 58, 35392 Giessen, Germany.
Müller
Christian E
CE
Schreiner
Peter R
PR
D000812:Anhydrides / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D003516:Cycloparaffins / Q000737:chemistry*; D004951:Esterification; D007700:Kinetics; D013237:Stereoisomerism
D000812:Anhydrides; D002264:Carboxylic Acids; D003516:Cycloparaffins