Pregnancy-related fibroid reduction.
We tested the hypothesis that the protective effect of parity on fibroids is due to direct pregnancy-related effects by following women from early pregnancy to postpartum period with ultrasound. Of 171 women with one initial fibroid, 36% had no identifiable fibroid at the time of postpartum ultrasound, and 79% of the remaining fibroids decreased in size.
Laughlin
Shannon K
SK
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA. laughlin.shannon@mayo.edu
Herring
Amy H
AH
Savitz
David A
DA
Olshan
Andrew F
AF
Fielding
Julia R
JR
Hartmann
Katherine E
KE
Baird
Donna D
DD
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology; D049590:Postpartum Period / Q000502:physiology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology*; D011859:Radiography; D047368:Tumor Burden; D016216:Ultrasonography, Prenatal; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology*
Gynecol Obstet Invest. 2009;67(2):137-44
19005262
J Reprod Med. 2006 Sep;51(9):671-4
17039693
Am J Public Health. 1996 Jun;86(6):858-62
8659663
J Am Assoc Gynecol Laparosc. 2004 May;11(2):138-52
15200765
Br J Obstet Gynaecol. 1996 Sep;103(9):909-14
8813312
Am J Obstet Gynecol. 2003 Jan;188(1):100-7
12548202
Am J Epidemiol. 2004 Jan 15;159(2):113-23
14718211
Br J Obstet Gynaecol. 1988 May;95(5):510-3
3042016
Fertil Steril. 1998 Sep;70(3):432-9
9757871
J Ultrasound Med. 1992 Oct;11(10):511-5
1404579
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19887-92
19047643
Fertil Steril. 2006 Jan;85(1):179-87
16412751
Arch Gynecol Obstet. 1999 Nov;263(1-2):13-6
10728621
Carcinogenesis. 2001 Dec;22(12):2049-52
11751438
Obstet Gynecol. 2009 Mar;113(3):630-635
19300327
Paediatr Perinat Epidemiol. 2004 Mar;18(2):143-52
14996255
Epidemiology. 2003 Mar;14(2):247-50
12606893
Hum Reprod. 2003 May;18(5):1088-93
12721189
Best Pract Res Clin Obstet Gynaecol. 2008 Aug;22(4):571-88
18534913