title: Adaptation effects to sleep studies in participants with and without chronic posttraumatic stress disorder.
abstract: The "first night effect" (FNE) is the alteration of sleep architecture observed on the first night of polysomnographic (PSG) studies. It is unclear whether the FNE reflects adaptation to the equipment, sleeping environment, or both. Moreover, it is possible that certain patient populations, such as those with posttraumatic stress disorder (PTSD), demonstrate greater adaptation effects that are highly context dependent. We assessed FNE in participants with PTSD and healthy controls in a cross-sectional study consisting of PSG testing at home and in the hospital. Contrary to our expectations, the PTSD group showed no adaptation effects in either setting. Only the control group assigned to the "hospital first" condition showed significant decreases in total sleep time on night 1 versus night 2 of the study. The results suggest that the FNE is related to adaptation to the combination of the hospital environment and the recording equipment.
authors.affiliation: Department of Psychiatry, University of California San Francisco, San Francisco, California, USA.
authors.forename: Ellen
authors.initials: E
authors.lastname: Herbst
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Metzler
authors.forename: Maryann
authors.initials: M
authors.lastname: Lenoci
authors.forename: Shannon E
authors.initials: SE
authors.lastname: McCaslin
authors.forename: Sabra
authors.initials: S
authors.lastname: Inslicht
authors.forename: Charles R
authors.initials: CR
authors.lastname: Marmar
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Neylan
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000150:complications / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry; D017286:Polysomnography / Q000523:psychology*; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology; D013313:Stress Disorders, Post-Traumatic / Q000503:physiopathology / Q000523:psychology*; D019966:Substance-Related Disorders / Q000150:complications / Q000503:physiopathology / Q000523:psychology
references.citation: J Psychiatr Res. 2001 May-Jun;35(3):165-72
references.pmid: 11461712
references.citation: Sleep. 1981 Sep;4(3):293-8
references.pmid: 7302460
references.citation: Electroencephalogr Clin Neurophysiol. 1967 Jun;22(6):556-8
references.pmid: 4164969
references.citation: Biol Psychiatry. 1999 Apr 1;45(7):938-41
references.pmid: 10202585
references.citation: Hosp Community Psychiatry. 1991 Mar;42(3):293-6
references.pmid: 2030013
references.citation: Chronobiol Int. 2005;22(5):905-15
references.pmid: 16298775
references.citation: Depress Anxiety. 2001;13(3):132-56
references.pmid: 11387733
references.citation: Sleep Med Rev. 2008 Jun;12(3):185-95
references.pmid: 17997114
references.citation: Behav Brain Res. 1991 Jan 31;42(1):7-11
references.pmid: 2029347
references.citation: Psychophysiology. 2007 Jul;44(4):660-9
references.pmid: 17521374
references.citation: Psychophysiology. 1966 Jan;2(3):263-6
references.pmid: 5903579
references.citation: Psychiatry Res. 2003 Sep 30;120(2):191-9
references.pmid: 14527650
references.citation: Biol Psychiatry. 2007 Apr 15;61(8):952-6
references.pmid: 17336940
references.citation: Psychiatry Res. 1989 May;28(2):193-213
references.pmid: 2748771
references.citation: Sleep. 1991 Feb;14(1):13-7
references.pmid: 1811313
references.citation: Psychophysiology. 2002 Jul;39(4):409-13
references.pmid: 12212632
references.citation: N Engl J Med. 2001 Dec 20;345(25):1825-32
references.pmid: 11752360
references.citation: Sleep. 1996 Nov;19(9):691-7
references.pmid: 9122554
references.citation: Sleep. 1995 Jul;18(6):463-9
references.pmid: 7481418
references.citation: Depress Anxiety. 2003;18(4):187-97
references.pmid: 14661188
references.citation: Neuropsychopharmacology. 2003 Sep;28(9):1666-76
references.pmid: 12799616
references.citation: Sleep. 1997 Dec;20(12):1119-26
references.pmid: 9493921
references.citation: J Sleep Res. 2003 Mar;12(1):35-41
references.pmid: 12603785
references.citation: Sleep. 1996 May;19(4):312-7
references.pmid: 8776789
references.citation: Biol Psychiatry. 1971;3(1):33-45
references.pmid: 4329270
references.citation: Psychophysiology. 1975 Jul;12(4):412-5
references.pmid: 169540
references.citation: J Trauma Stress. 1995 Jan;8(1):75-90
references.pmid: 7712061
references.citation: Neuropsychopharmacology. 2005 Jun;30(6):1173-80
references.pmid: 15714228
references.citation: Am J Psychiatry. 1998 Jul;155(7):929-33
references.pmid: 9659859
references.citation: Ann Intern Med. 1993 Sep 15;119(6):449-53
references.pmid: 8357109
references.citation: J Clin Psychiatry. 2000;61 Suppl 7:33-9
references.pmid: 10795607
references.citation: J Trauma Stress. 2007 Aug;20(4):619-23
references.pmid: 17721964
references.citation: Sleep. 1988 Jun;11(3):273-6
references.pmid: 3399780