title: Paraneoplastic pandysautonomia as a manifestation of non-small cell lung cancer.
abstract: Pandysautonomia is a severe and rare clinical condition characterized by widespread sympathetic and parasympathetic dysfunction. Consideration of whether symptoms and presentation are acute, subacute, or chronic is often helpful in establishing a differential diagnosis. The underlying mechanisms leading to pure pandysautonomia are unclear; however, there is some evidence suggestive of an immune-mediated pathogenesis. Herein, we report a case with pandysautonomia as a paraneoplastic manifestation of non-small cell lung cancer that had an excellent response to symptomatic and supportive treatments, as well as IVIG therapy.
authors.affiliation: Department of Neurology, Marmara University Hospital, Tophanelioğlu cad. 13/15, Altunizade, Istanbul, Turkey. kayihanu@yahoo.com
authors.forename: Kayihan
authors.initials: K
authors.lastname: Uluc
authors.forename: Muge
authors.initials: M
authors.lastname: Kocak
authors.forename: Pinar Kahraman
authors.initials: PK
authors.lastname: Koytak
authors.forename: Deniz
authors.initials: D
authors.lastname: Borucu
authors.forename: Baris
authors.initials: B
authors.lastname: Isak
authors.forename: Sevinc
authors.initials: S
authors.lastname: Aktan
authors.forename: Onder
authors.initials: O
authors.lastname: Us
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D054969:Primary Dysautonomias / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D011877:Radionuclide Imaging
chemical_list: D016756:Immunoglobulins, Intravenous
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