[Investigation and analysis of the common inhaled allergens in allergic diseases in Jingmen area of Hubei Province].
OBJECTIVE
In order provide important evidences for epidemiologic survey, clinical diagnosis, treatment and preservation of allergic diseases in this area, we investigate the distribution of the common allergens in allergic rhinitis and allergic asthma in Jingmen area and the sensitization condition of the major allergen house dust mite.


METHODS
Four hundred and twenty-five patients with suspected allergic rhinitis and asthma in our area accepted skin prick tests of 10 standard allergen agents and specificity IgE detection. The different positivity ratios of allergens in different age groups were compared and the correlation between the two different technique methods testing the dust mite allergen was analyzed.


RESULTS
Among 425 patients with suspected allergic rhinitis and asthma in our area, 298 patients were positive and 89 patients suffered a combined allergic asthma. House dust mite (292 cases) and dermatophagoides farinae (289 cases) were the commonest allergens. The other common allergens were mugwort (45), ragweed (31), fungus I (19), fungus II (15), spring-pollen II (14), poly-animal hair (14), spring-pollen I (9), poly-feather (3). There was a correlation between skin test and sIgE test for house dust mite, dermatophagoides farinae in children group, and the positivity ratios were significantly higher than the adults group.


CONCLUSIONS
Dust mite is the most important allergen in allergic rhinitis and asthma in Jingmen.
Zhao
Yan
Y
Department of Otorhinolaryngology, the First Public Hospital, Jingmen, 448000, China.
Huang
Fang
F
He
Jingpei
J
Deng
Pingping
P
Zhou
Ping
P
Zhou
Jingjie
J
Zhao
Xigui
X
Yang
Zili
Z
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000032:analysis* / Q000276:immunology; D000818:Animals; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D039981:Pyroglyphidae; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D012882:Skin Tests; D055815:Young Adult
D000485:Allergens; D007073:Immunoglobulin E