Renal smooth muscle hamartoma.
A large (4 cm in diameter) smooth muscle tumor was found in the medial aspect of the right kidney in a 54-year-old Caucasian woman with acute hypertension. Clonality assay (HUMARA) showed no evidence of clonal proliferation, and array comparative genomic hybridization (aCGH) analysis failed to identify any copy number genomic change. These findings are consistent with smooth muscle hamartoma, a rare benign renal tumor-like lesion.
Gatalica
Zoran
Z
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA. zorangatalica@creighton.edu
Hes
Ondrej
O
Vanecek
Tomas
T
Sanger
Warren
W
D002999:Clone Cells; D055028:Comparative Genomic Hybridization; D004247:DNA / Q000032:analysis; D019175:DNA Methylation / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006222:Hamartoma / Q000235:genetics / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology; D007674:Kidney Diseases / Q000150:complications / Q000235:genetics / Q000473:pathology*; D007889:Leiomyoma / Q000175:diagnosis; D007890:Leiomyosarcoma / Q000175:diagnosis; D008875:Middle Aged; D009130:Muscle, Smooth / Q000473:pathology*; D011944:Receptors, Androgen / Q000235:genetics
D011944:Receptors, Androgen; D004247:DNA