title: Gold(I)-catalyzed rearrangement of propargyl benzyl ethers: a practical method for the generation and in situ transformation of substituted allenes.
abstract: A series of benzyl propargyl ethers react with a gold(I) catalyst to furnish variously substituted allenes via a 1,5-hydride shift/fragmentation sequence. This transformation is rapid and practical. It can be performed under very mild conditions (room temperature or 60 degrees C) using terminal as well as substituted alkyne substrates bearing a primary, secondary, or tertiary benzyl ether group. The allenes thus formed can be reacted in situ with an internal or external nucleophile, corresponding to an overall reductive substitution process, to produce more functionalized compounds.
authors.affiliation: Département de Chimie, UMR 7652, CNRS/Ecole Polytechnique, 91128 Palaiseau, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Bolte
authors.forename: Yann
authors.initials: Y
authors.lastname: Odabachian
authors.forename: Fabien
authors.initials: F
authors.lastname: Gagosz