Persistent corneal endothelial deposits associated with rifabutin therapy for Crohn's disease.
OBJECTIVE
To report a case of corneal endothelial deposits associated with rifabutin therapy for Crohn's disease.


METHODS
Case report, anterior segment photography, and current literature search.


RESULTS
Persistence of corneal endothelial deposits was found to occur in a 55-year-old gentleman 6 years after cessation of a 3-year course of rifabutin. The corneal deposits were not associated with lenticular findings or retinal dysfunction, the latter side effect being published in a recent research article.


CONCLUSIONS
This is only the second published case of corneal deposits in conjunction with rifabutin therapy for Crohn's disease. This case uniquely confirms the persistence of the corneal deposits longer than previously documented.
Williams
Katie
K
West Kent Eye Centre, Princess Royal University Hospital, South London NHS Trust, Orpington, Kent, United Kingdom. kmw.email@gmail.com
Ilari
Luca
L
D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003316:Corneal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003424:Crohn Disease / Q000188:drug therapy*; D004728:Endothelium, Corneal / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017828:Rifabutin / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D017828:Rifabutin