Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates.
The assembly of double-stranded (ds) DNA nanocircles both by hybridization with branched oligodeoxynucleotides (ODNs) and by intercalation was analyzed by atomic force microscopy (AFM). Branched ODNs ligated to single-stranded (ss) gap regions of dsDNA nanocircles led to defined, dumbbell-shaped architectures. ODNs containing an aromatic intercalator yielded oligomeric aggregates.
Ackermann
Damian
D
LIMES Institute, Chemical Biology & Medicinal Chemistry Unit, University of Bonn, 53121 Bonn, Germany.
Rasched
Goran
G
Verma
Sandeep
S
Schmidt
Thorsten L
TL
Heckel
Alexander
A
Famulok
Michael
M
D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D018625:Microscopy, Atomic Force; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*
D009838:Oligodeoxyribonucleotides; D004247:DNA