title: Phosphoinositide-binding interface proteins involved in shaping cell membranes.
abstract: The mechanism by which cell and cell membrane shapes are created has long been a subject of great interest. Among the phosphoinositide-binding proteins, a group of proteins that can change the shape of membranes, in addition to the phosphoinositide-binding ability, has been found. These proteins, which contain membrane-deforming domains such as the BAR, EFC/F-BAR, and the IMD/I-BAR domains, led to inward-invaginated tubes or outward protrusions of the membrane, resulting in a variety of membrane shapes. Furthermore, these proteins not only bind to phosphoinositide, but also to the N-WASP/WAVE complex and the actin polymerization machinery, which generates a driving force to shape the membranes.
authors.affiliation: Laboratory of Lipid Biochemistry, Graduate School of Medicine, Kobe University, Hyogo, Japan. takenawa@med.kobe-u.ac.jp
authors.forename: Tadaomi
authors.initials: T
authors.lastname: Takenawa
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D010716:Phosphatidylinositols / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D010716:Phosphatidylinositols; D011506:Proteins
references.citation: Dev Cell. 2005 Dec;9(6):791-804
references.pmid: 16326391
references.citation: FEBS Lett. 2003 Nov 6;554(1-2):30-4
references.pmid: 14596909
references.citation: J Cell Sci. 2008 Feb 1;121(Pt 3):379-90
references.pmid: 18198193
references.citation: EMBO J. 2005 Jan 26;24(2):240-50
references.pmid: 15635447
references.citation: J Biol Chem. 1990 May 25;265(15):8382-6
references.pmid: 2160454
references.citation: Structure. 2007 Jul;15(7):839-52
references.pmid: 17540576
references.citation: Prog Lipid Res. 2009 Sep;48(5):298-305
references.pmid: 19481110
references.citation: J Biol Chem. 1987 Sep 5;262(25):12228-36
references.pmid: 3040735
references.citation: EMBO J. 2008 Nov 5;27(21):2817-28
references.pmid: 18923421
references.citation: Annu Rev Physiol. 2003;65:761-89
references.pmid: 12471164
references.citation: Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4379-83
references.pmid: 15070726
references.citation: Biochem J. 2001 Dec 15;360(Pt 3):513-30
references.pmid: 11736640
references.citation: Nature. 1998 Jul 30;394(6692):433-4
references.pmid: 9697765
references.citation: J Mol Med (Berl). 2007 Jun;85(6):569-76
references.pmid: 17497115
references.citation: Nature. 1998 Jan 1;391(6662):93-6
references.pmid: 9422512
references.citation: Proc Natl Acad Sci U S A. 1988 Dec;85(23):9057-61
references.pmid: 2848254
references.citation: J Cell Biol. 2006 May 22;173(4):571-85
references.pmid: 16702231
references.citation: Mol Cell Biol. 1997 Jul;17(7):3841-9
references.pmid: 9199318
references.citation: Trends Cell Biol. 2008 Feb;18(2):52-60
references.pmid: 18215522
references.citation: Eur J Cell Biol. 2004 Feb;83(1):13-8
references.pmid: 15085951
references.citation: J Biol Chem. 2009 Mar 27;284(13):8548-56
references.pmid: 19155218
references.citation: Dev Cell. 2003 Oct;5(4):595-609
references.pmid: 14536061
references.citation: J Cell Sci. 2005 Nov 15;118(Pt 22):5393-403
references.pmid: 16280553
references.citation: Curr Biol. 1998 Aug 27;8(17):959-62
references.pmid: 9742397
references.citation: Annu Rev Biochem. 2009;78:857-902
references.pmid: 19317650
references.citation: Nat Cell Biol. 2004 Apr;6(4):319-27
references.pmid: 15048123
references.citation: EMBO J. 2002 Nov 15;21(22):6083-94
references.pmid: 12426380
references.citation: Blood. 1986 Dec;68(6):1329-32
references.pmid: 3779101
references.citation: Science. 2001 Feb 9;291(5506):1047-51
references.pmid: 11161217
references.citation: J Cell Sci. 2004 Aug 1;117(Pt 17):3839-53
references.pmid: 15265985
references.citation: Nature. 1992 Sep 10;359(6391):150-2
references.pmid: 1326084
references.citation: J Cell Biol. 2006 Jan 16;172(2):269-79
references.pmid: 16418535
references.citation: EMBO J. 2006 Jun 21;25(12):2889-97
references.pmid: 16763557
references.citation: Nature. 2002 Aug 15;418(6899):790-3
references.pmid: 12181570
references.citation: J Exp Med. 1992 Sep 1;176(3):867-74
references.pmid: 1512549
references.citation: Nat Rev Mol Cell Biol. 2007 Jan;8(1):37-48
references.pmid: 17183359
references.citation: J Neurosci. 2005 Mar 9;25(10):2670-81
references.pmid: 15758177
references.citation: Traffic. 2008 Jan;9(1):133-46
references.pmid: 17988218
references.citation: Genes Cells. 2006 Mar;11(3):281-92
references.pmid: 16483316
references.citation: J Neurochem. 2004 Aug;90(3):659-65
references.pmid: 15255944
references.citation: Sci Signal. 2009 Sep 08;2(87):ra52
references.pmid: 19738202
references.citation: J Biol Chem. 2003 Feb 21;278(8):6461-9
references.pmid: 12477732
references.citation: Biochim Biophys Acta. 2001 Oct 31;1533(3):190-206
references.pmid: 11731330
references.citation: Cell. 1999 Apr 16;97(2):221-31
references.pmid: 10219243
references.citation: J Biol Chem. 2005 Aug 19;280(33):29849-55
references.pmid: 15929989
references.citation: J Cell Sci. 2003 Jan 15;116(Pt 2):239-46
references.pmid: 12482910
references.citation: J Biol Chem. 1994 Feb 25;269(8):5489-92
references.pmid: 8119878
references.citation: Nat Cell Biol. 2001 Jul;3(7):613-8
references.pmid: 11433291
references.citation: J Biol Chem. 2003 Mar 7;278(10):8452-9
references.pmid: 12482861
references.citation: EMBO J. 2006 Jun 21;25(12):2898-910
references.pmid: 16763559
references.citation: Cell. 2003 Feb 21;112(4):453-65
references.pmid: 12600310
references.citation: J Cell Biol. 2003 Sep 15;162(6):1079-88
references.pmid: 12975351
references.citation: Neuron. 2008 Jun 12;58(5):736-48
references.pmid: 18549785
references.citation: Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12700-5
references.pmid: 19549836
references.citation: Science. 1988 Feb 5;239(4840):640-3
references.pmid: 2829356
references.citation: Science. 2004 Jan 23;303(5657):495-9
references.pmid: 14645856
references.citation: Nat Cell Biol. 2008 Mar;10(3):306-13
references.pmid: 18278037
references.citation: Curr Biol. 2001 Oct 30;11(21):1645-55
references.pmid: 11696321
references.citation: Nat Cell Biol. 2001 Jul;3(7):675-8
references.pmid: 11433300
references.citation: EMBO J. 1998 Dec 1;17(23):6932-41
references.pmid: 9843499
references.citation: IUBMB Life. 2006 May-Jun;58(5-6):296-303
references.pmid: 16754321
references.citation: J Cell Biol. 2000 Sep 18;150(6):1299-310
references.pmid: 10995436
references.citation: Curr Biol. 2003 Sep 2;13(17):1480-7
references.pmid: 12956949
references.citation: EMBO J. 1996 Oct 1;15(19):5326-35
references.pmid: 8895577
references.citation: J Cell Biol. 2000 Mar 6;148(5):1047-62
references.pmid: 10704453
references.citation: Nature. 1985 Apr 4-10;314(6010):472-4
references.pmid: 2984579
references.citation: J Biol Chem. 2004 Sep 17;279(38):40091-9
references.pmid: 15252009
references.citation: Curr Biol. 2009 Jan 27;19(2):95-107
references.pmid: 19150238
references.citation: Traffic. 2009 Feb;10(2):246-57
references.pmid: 19054385
references.citation: Biochem J. 1996 Jun 1;316 ( Pt 2):639-45
references.pmid: 8687411
references.citation: Nat Cell Biol. 2004 May;6(5):420-6
references.pmid: 15107862
references.citation: FEBS Lett. 1995 Dec 4;376(3):172-6
references.pmid: 7498535
references.citation: PLoS One. 2009 May 25;4(5):e5678
references.pmid: 19479071
references.citation: Nature. 2000 Dec 7;408(6813):732-5
references.pmid: 11130076
references.citation: Nat Rev Mol Cell Biol. 2003 Feb;4(2):127-39
references.pmid: 12563290
references.citation: Nat Cell Biol. 2008 Mar;10(3):259-71
references.pmid: 18297063
references.citation: Cell. 1994 Aug 26;78(4):635-44
references.pmid: 8069912
references.citation: Cell. 2007 May 18;129(4):761-72
references.pmid: 17512409
references.citation: J Cell Sci. 2009 Jul 1;122(Pt 13):2283-91
references.pmid: 19509061
references.citation: J Biol Chem. 1997 Mar 21;272(12):7578-81
references.pmid: 9065410
references.citation: Cell. 2005 Oct 21;123(2):305-20
references.pmid: 16239147
references.citation: J Cell Sci. 2000 Dec;113 Pt 24:4511-21
references.pmid: 11082044
references.citation: Mol Cell Biol. 2002 Nov;22(22):7889-906
references.pmid: 12391157
references.citation: J Biol Chem. 2008 Jul 18;283(29):20454-72
references.pmid: 18448434
references.citation: Dev Biol. 2008 Dec 15;324(2):297-309
references.pmid: 18938151
references.citation: Nature. 1994 Sep 8;371(6493):168-70
references.pmid: 8072546
references.citation: Biochem Biophys Res Commun. 1999 Jun 24;260(1):296-302
references.pmid: 10381382
references.citation: J Biochem. 2006 Apr;139(4):663-70
references.pmid: 16672266
references.citation: J Biol Chem. 2006 Nov 17;281(46):35347-58
references.pmid: 17003044
references.citation: Ann N Y Acad Sci. 1995 Sep 7;766:31-43
references.pmid: 7486679
references.citation: Nature. 1998 Jul 30;394(6692):432-3
references.pmid: 9697764
references.citation: J Cell Biol. 2007 Mar 26;176(7):953-64
references.pmid: 17371834
references.citation: J Biol Chem. 2004 Apr 9;279(15):14929-36
references.pmid: 14752106
references.citation: J Biol Chem. 1994 Jan 14;269(2):1518-22
references.pmid: 8288618
references.citation: J Cell Biol. 1996 Oct;135(1):37-51
references.pmid: 8858161
references.citation: Mol Cell. 2009 Nov 13;36(3):512-24
references.pmid: 19917258
references.citation: Nature. 2002 Sep 26;419(6905):361-6
references.pmid: 12353027
references.citation: Biochem J. 2000 Aug 15;350 Pt 1:1-18
references.pmid: 10926821
references.citation: Science. 1992 Oct 23;258(5082):607-14
references.pmid: 1411571
references.citation: Nature. 1996 Jun 6;381(6582):531-5
references.pmid: 8632828
references.citation: Nature. 2003 Jul 24;424(6947):452-6
references.pmid: 12879075
references.citation: J Biol Chem. 2006 May 12;281(19):13285-13299
references.pmid: 16540475
references.citation: Cell. 2004 Jul 23;118(2):203-16
references.pmid: 15260990
references.citation: J Cell Biol. 2001 Feb 5;152(3):579-94
references.pmid: 11157984
references.citation: Cell. 2009 Sep 4;138(5):990-1004
references.pmid: 19737524
references.citation: Cell. 1996 Mar 8;84(5):723-34
references.pmid: 8625410
references.citation: Cell Signal. 2002 Sep;14(9):733-43
references.pmid: 12034354