title: [Cardiac functional analysis with MRI].
abstract: Cardiovascular diseases (CVD) are among the leading causes of death worldwide. Even in the 21(st) century CVD will still be the most frequent cause of morbidity and mortality. Precise evaluation of cardiac function is therefore mandatory for therapy planning and monitoring. In this article the contribution of MRI-based analysis of cardiac function will be addressed. Nowadays cine-MRI is considered as the standard of reference (SOR) in cardiac functional analysis. ECG-triggered steady-state free precession (SSFP) sequences are mainly used as they stand out due to short acquisition times and excellent contrast between the myocardium and the ventricular cavity. An indispensible requirement for cardiac functional analysis is an exact planning of the examination and based on that the coverage of the whole ventricle in short axial slices. By means of dedicated post-processing software, manual or semi-automatic segmentation of the endocardial and epicardial contours is necessary for functional analysis. In this way end-diastolic volume (EDV), end-systolic volume (ESV) and the ejection fraction (EF) are defined and regional wall motion abnormalities (RWMA) can be detected.
authors.affiliation: Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Marchioninistr. 15, 81377, München, Deutschland. Torleif.Sandner@med.uni-muenchen.de
authors.forename: T A
authors.initials: TA
authors.lastname: Sandner
authors.forename: D
authors.initials: D
authors.lastname: Theisen
authors.forename: K U
authors.initials: KU
authors.lastname: Bauner
authors.forename: M
authors.initials: M
authors.lastname: Picciolo
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
authors.forename: B J
authors.initials: BJ
authors.lastname: Wintersperger
mesh_terms: D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D006334:Heart Function Tests / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis*
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