EPONYM. Sweet syndrome.
Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain drugs. Although drug-induced Sweet syndrome is rare, granulocyte colony-stimulating factor, all-trans-retinoic acid, and miscellaneous drugs have been implicated in causing this disorder in adults. In pediatric patients, granulocyte colony-stimulating factor, all-trans-retinoic acid, trimethoprim-sulfamethoxazole, and azathioprine have been implicated as potential causes of drug-induced Sweet syndrome. To date, six cases, including the patient reported here, have been reported in children.
Kim
Mi Jin
MJ
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, South Korea.
Choe
Yon Ho
YH
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D002648:Child; D003240:Connective Tissue Diseases / Q000150:complications / Q000188:drug therapy; D004890:Erythema / Q000139:chemically induced / Q000503:physiopathology; D005334:Fever / Q000503:physiopathology; D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects*; D006801:Humans; D007239:Infections / Q000150:complications / Q000188:drug therapy; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000209:etiology / Q000503:physiopathology; D014212:Tretinoin / Q000009:adverse effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
D016179:Granulocyte Colony-Stimulating Factor; D014212:Tretinoin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D001379:Azathioprine
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