Detection of low-populated reaction intermediates with hyperpolarized NMR.
Hyperpolarized (13)C NMR spectroscopy can provide the sensitivity and spectral resolution to detect, identify and quantify low-populated reaction intermediates, thus yielding direct chemical information on reaction mechanisms in real-time assays.
Jensen
Pernille R
PR
Albeda Research, Gamle Carlsberg Vej 10, 2500 Valby, Denmark.
Meier
Sebastian
S
Ardenkjaer-Larsen
Jan H
JH
Duus
Jens Ø
JØ
Karlsson
Magnus
M
Lerche
Mathilde H
MH
D000106:Acetate-CoA Ligase / Q000737:chemistry* / Q000378:metabolism; D000085:Acetates / Q000737:chemistry*; D002247:Carbon Isotopes; D002384:Catalysis; D004789:Enzyme Activation; D019811:Hydroxylamine / Q000737:chemistry*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D000085:Acetates; D002247:Carbon Isotopes; D019811:Hydroxylamine; D000106:Acetate-CoA Ligase