title: Negative effects of chronic kidney failure on lung function and functional capacity.
abstract: OBJECTIVE
  To evaluate lung function and functional capacity in patients with chronic kidney failure (CKF) undergoing dialysis and in patients after kidney transplant.
  
  
  METHODS
  Seventy-two participants were evaluated: 32 patients with CKF on dialysis (DG) for at least six months, ten patients who had kidney transplants (TG) at least six months earlier, and 30 healthy subjects as a control group (CG). All groups were evaluated using spirometry, with maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), and using the six-minute walking test (6MWT). The SPSS 12.0 software was used for statistical analysis, with a minimum significance level of alpha<0.05.
  
  
  RESULTS
  There was a decreased lung function in the DG for FVC, FEV1, MVV, VC, MIP and MEP, and decreased FEV1 and MVV in the TG compared to the CG (one-way ANOVA/Fisher's post-hoc; p<0.01). There was also an association (chi-square) between decreased MIP and belonging to the DG (alpha=0.5, p<0.001), between lower performance in the 6MWT for the DG and TG (p<0.01) compared to the CG (one-way ANOVA/Fisher's post-hoc), and between MIP and MEP (Pearson's coefficient; r=0.752; p<0.01).
  
  
  CONCLUSIONS
  Patients with CKF undergoing dialysis showed impaired functional capacity and lung function that were not completely reverted in the kidney transplant patients.
authors.affiliation: Department of Physical Therapy, Centro Universitário da Grande Dourados, Dourados, Brasil. julianalc@gmail.com
authors.forename: Juliana L
authors.initials: JL
authors.lastname: Cury
authors.forename: Antonio F
authors.initials: AF
authors.lastname: Brunetto
authors.forename: Ricardo D
authors.initials: RD
authors.lastname: Aydos
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D016030:Kidney Transplantation; D008168:Lung / Q000503:physiopathology*; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis