Resistin concentration is increased in the peritoneal fluid of women with endometriosis.
OBJECTIVE
The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis.


METHODS
PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay.


RESULTS
The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis.


CONCLUSIONS
The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis.
Yi
Kyong Wook
KW
Department of Obstetrics and Gynecology, Korea University, Seoul, Korea.
Shin
Jung-Ho
JH
Park
Hyun Tae
HT
Kim
Tak
T
Kim
Sun Haeng
SH
Hur
Jun-Young
JY
D052242:Adiponectin / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D001202:Ascitic Fluid / Q000276:immunology / Q000378:metabolism*; D015992:Body Mass Index; D001835:Body Weight; D004715:Endometriosis / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D012044:Regression Analysis; D052243:Resistin / Q000276:immunology / Q000378:metabolism*; D055105:Waist Circumference; D049629:Waist-Hip Ratio
D052242:Adiponectin; D052243:Resistin