Transcatheter repair of perivalvular regurgitation.
Hemodynamically significant perivalvular regurgitation affects about 1.5% of all prosthetic valve implants. Reoperation carries increased risk--especially in the setting of concomitant comorbidities of left ventricular dysfunction, prior coronary artery bypass grafts, renal dysfunction, and advanced age. Transcatheter closure of the perivalvular regurgitant channel using a variety of occluders has been available for several years; however, recent improvements in technology and technique have made this therapy more effective and available to a wider group of patients. This article describes the recent advances and the state of the art of this therapy.
Love
Barry A
BA
Division of Pediatric Cardiology, Mount Sinai School of Medicine, New York, NY 10029, USA. barry.love@mssm.edu
Fischer
Gregory W
GW
Mittnacht
Alexander
A
Kalman
Jill
J
Adams
David H
DH
D006328:Cardiac Catheterization / Q000379:methods*; D017548:Echocardiography, Transesophageal / Q000379:methods; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D011475:Prosthesis Failure; D012086:Reoperation; D012307:Risk Factors; D016896:Treatment Outcome