title: Treatment of osteonecrosis of the femoral head in lymphoma patients by free vascularised fibular grafting.
abstract: The purpose of this study was to assess the outcomes of treatment of femoral head osteonecrosis using free vascularised fibular grafting in patients with Hodgkin's disease and non-Hodgkin's lymphoma. We retrospectively reviewed seven patients (14 hips) with lymphoma who underwent free vascularised fibular grafting for osteonecrosis of the femoral head, evaluating pre- and postoperative Harris hip scores, visual analog scale (VAS) pain scores, hip range of motion and radiographs. Patients were followed up for a minimum of 1.5 years (mean, 3.3 years). All these patients exhibited good recovery without severe life-threatening complications. The mean Harris hip score improved from 69 to 88, while average VAS pain score decreased from 54 to 18. At the latest follow-up, we found improvement or unchanged radiographs in all three hips with initial Steinberg stage II osteonecrosis and in nine of 11 hips with stage III or IV osteonecrosis. No hips failed treatment and underwent total hip arthroplasty. The clinical data demonstrated that free vascularised fibular grafting can slow or even halt progression of necrosis, and improve the function of the hip and quality of life in lymphoma patients.
authors.affiliation: Department of Orthopaedic Surgery, Shanghai Jiao Tong University, Shanghai Sixth People's Hospital, Shanghai, China.
authors.forename: Si
authors.initials: S
authors.lastname: Yin
authors.forename: Changqing
authors.initials: C
authors.lastname: Zhang
authors.forename: Dongxu
authors.initials: D
authors.lastname: Jin
authors.forename: Shengbao
authors.initials: S
authors.lastname: Chen
authors.forename: Yuan
authors.initials: Y
authors.lastname: Sun
authors.forename: Jiageng
authors.initials: J
authors.lastname: Sheng
mesh_terms: D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005271:Femur Head Necrosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005360:Fibula / Q000098:blood supply / Q000637:transplantation*; D006304:Health Status; D006621:Hip Joint / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008223:Lymphoma / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011788:Quality of Life; D020127:Recovery of Function; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult
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