title: BRCA carriers' thoughts on risk management in relation to preimplantation genetic diagnosis and childbearing: when too many choices are just as difficult as none.
abstract: Women with a BRCA mutation have unique concerns about childbearing and future fertility. In a focus group conducted among unaffected carriers, the majority of women held positive attitudes toward preimplantation genetic diagnosis to reduce transmission to future offspring and further identified unmet needs for education and support for decision making.
authors.affiliation: Health Outcomes and Behavior Program, Division of Population Sciences, Moffitt Cancer Center, Department of Oncologic Science, College of Medicine, University of South Florida, Tampa, Florida 33612, USA. gwen.quinn@moffitt.org
authors.forename: Gwendolyn P
authors.initials: GP
authors.lastname: Quinn
authors.forename: Susan T
authors.initials: ST
authors.lastname: Vadaparampil
authors.forename: Sharon
authors.initials: S
authors.lastname: Tollin
authors.forename: Cheryl A
authors.initials: CA
authors.lastname: Miree
authors.forename: Devin
authors.initials: D
authors.lastname: Murphy
authors.forename: Bethanne
authors.initials: B
authors.lastname: Bower
authors.forename: Celso
authors.initials: C
authors.lastname: Silva
mesh_terms: D022126:Access to Information; D000328:Adult; D001294:Attitude to Health; D002755:Choice Behavior / Q000502:physiology; D004644:Emotions / Q000502:physiology; D005260:Female; D019398:Genes, BRCA1; D024522:Genes, BRCA2; D006301:Health Services Needs and Demand; D006579:Heterozygote; D006801:Humans; D009154:Mutation / Q000502:physiology; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000379:methods / Q000523:psychology*; D012098:Reproduction / Q000235:genetics / Q000502:physiology; D043762:Reproductive Behavior / Q000502:physiology / Q000523:psychology; D018570:Risk Assessment / Q000379:methods; D012944:Social Support; D013850:Thinking / Q000502:physiology