Validity of the telephone interview for cognitive status (TICS) and modified TICS (TICSm) for mild cognitive imparment (MCI) and dementia screening.
This study aimed to validate the TICS and modified TICS (TICSm) in Korean elderly population and to compare MCI and dementia screening ability between TICS and TICSm. TICS and TICSm were administered to 70 cognitively normal (CN), 75 MCI, and 85 dementia subjects, with mini-mental state examination (MMSE) and other cognitive and functional measures. TICS and TICSm scores were highly correlated with other global cognitive and functional scores. The CN vs. dementia discrimination ability of both instruments was as excellent as that of MMSE (sensitivity/specificity at optimal cutoff: 87.1/90.1 for TICS; 88.2/90.0 for TICSm). Although their CN vs. MCI discrimination performances were comparable to that of MMSE, they were far from perfect (sensitivity/specificity: 69.3/68.6 for TICS; 73.3/67.1 for TICSm). There was no significant difference in dementia or MCI screening accuracy between TICS and TICSm. Both of them also showed high test-retest reliability. Our findings indicate that TICS and TICSm are reliable and as valid as MMSE in regard of screening cognitively impaired elderly. In terms of the comparison between TICSm and TICS, however, TICSm has little advantage over TICS for screening dementia and even MCI, in spite of longer administration time and more efforts required.
Seo
Eun Hyun
EH
Interdisciplinary Program for Cognitive Science, Seoul National University, 599 Kwanak-ro, Kwanak-gu, Seoul 151-742, Republic of Korea.
Lee
Dong Young
DY
Kim
Shin Gyeom
SG
Kim
Ki Woong
KW
Kim
Do Hoon
DH
Kim
Bong Jo
BJ
Kim
Moon-Doo
MD
Kim
Seong Yoon
SY
Kim
Young Hoon
YH
Kim
Jeong-Lan
JL
Kim
Jee Wook
JW
Moon
Seok Woo
SW
Park
Joon Hyuck
JH
Ryu
Seung-Ho
SH
Yoon
Jong Choul
JC
Lee
Nam Jin
NJ
Lee
Chang Uk
CU
Jhoo
Jin Hyeong
JH
Choo
Ll Han
LH
Woo
Jong Inn
JI
D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards; D015203:Reproducibility of Results; D056910:Republic of Korea; D012680:Sensitivity and Specificity