title: A call to standardize teratoma assays used to define human pluripotent cell lines.
abstract: The teratoma assay is the gold standard for documenting pluripotency of human stem cells. However, reports of new human ESC and iPSC lines vary widely in both methods and analysis of teratoma data. We call for consensus standards to be established to make this assay worthy of its "golden" status.
authors.affiliation: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA. fj.mueller@zip.kiel.de
authors.forename: Franz-Josef
authors.initials: FJ
authors.lastname: Müller
authors.forename: Johanna
authors.initials: J
authors.lastname: Goldmann
authors.forename: Peter
authors.initials: P
authors.lastname: Löser
authors.forename: Jeanne F
authors.initials: JF
authors.lastname: Loring
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods* / Q000592:standards*; D002460:Cell Line; D032921:Consensus; D006801:Humans; D015201:Meta-Analysis as Topic; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology*; D012015:Reference Standards; D013724:Teratoma / Q000473:pathology*