title: Intervention with education and exercise reverses the metabolic syndrome in adults.
abstract: About 29% of the adult population of Talca, Chile, suffers from the metabolic syndrome (MS), a value higher than the national prevalence. Evidence indicates that exercise and nutritional changes reduce the predominance of this syndrome. The goal of this study was to evaluate the effects of a structured interventional program of physical activity and nutritional counseling in adults with MS. Fifty-one subjects were studied: 27 were included in the interventional program (I-MS). The control group was formed by 24 individuals who did not participate in the program (NI-MS). We assessed body weight, corporal composition, arterial pressure, glycemia, and lipid profile at baseline and after 18 weeks of treatment. After this period, the I-SM group showed a significant decrease in triglycerides (geometric mean 202.2 to 110.5 mg/dL, P < .001), diastolic blood pressure (mean 85.4 to 79.6 mm Hg, P = .001), waist circumference (mean men 101.5 to 94.1 cm, P < .001; mean women 107.2 to 96.2 cm, P < .001), weight (mean 81.1 to 77.2 kg, P < .001), and body mass index (mean 31.8 to 30.2 kg/m(2), P < .001). In the NI-MS group, the individual parameters did not change significantly. Our results show that a non-pharmacological treatment based on exercise exerts an important beneficial effect in patients with MS, mainly on the waist circumference, blood pressure, and triglycerides.
authors.affiliation: Escuela de Medicina, Universidad de Talca, Talca, Chile. vmujica@utalca.cl
authors.forename: Verónica
authors.initials: V
authors.lastname: Mujica
authors.forename: Alberto
authors.initials: A
authors.lastname: Urzúa
authors.forename: Elba
authors.initials: E
authors.lastname: Leiva
authors.forename: Nora
authors.initials: N
authors.lastname: Díaz
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Moore-Carrasco
authors.forename: Marcela
authors.initials: M
authors.lastname: Vásquez
authors.forename: Edgardo
authors.initials: E
authors.lastname: Rojas
authors.forename: Gloria
authors.initials: G
authors.lastname: Icaza
authors.forename: Carla
authors.initials: C
authors.lastname: Toro
authors.forename: Roxana
authors.initials: R
authors.lastname: Orrego
authors.forename: Iván
authors.initials: I
authors.lastname: Palomo
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D002677:Chile / Q000453:epidemiology; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology / Q000534:rehabilitation*; D008875:Middle Aged; D010353:Patient Education as Topic / Q000379:methods*; D015995:Prevalence; D017678:Sex Distribution; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D008055:Lipids