Motor proteins: kinesin drives with an underhead cam.
A high-resolution cryo-EM structure of kinesin bound to its microtubule track allows for near-atomistic visualization of nucleotide-dependent conformational changes in this motor protein.
Lang
Matthew J
MJ
Department of Biological Engineering, MIT, Cambridge, MA 02139, USA. mjlang@mit.edu
Hwang
Wonmuk
W
D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D004734:Energy Metabolism / Q000502:physiology; D016547:Kinesins / Q000502:physiology / Q000648:ultrastructure*; D008870:Microtubules / Q000502:physiology / Q000648:ultrastructure; D009038:Motion
D000255:Adenosine Triphosphate; D016547:Kinesins