title: Prevention of adverse health trajectories in a vulnerable elderly population through nurse home visits: a randomized controlled trial [ISRCTN05358495].
abstract: OBJECTIVE
  Can indicative prevention of home-visiting nurses be effective when targeted at a frail senior population using multidimensional geriatric assessments and personalized care plans?
  
  
  METHODS
  We performed an individually randomized controlled trial in 33 blinded primary care practices over 18 months. The 651 participants were aged 75 years or older, lived at home, and were frail but neither terminally ill nor demented. A score in the lowest quartile on at least two of six self-reported functional health domains (COOP-WONCA charts), defined frail health. We compared usual care with proactive home visits by trained community nurses. The nurses (a) assessed the care needs with a multidimensional computerized geriatric instrument, which enabled direct identification of health risks; (b) determined care priorities together with the person; (c) designed and executed individually tailored interventions; and (d) monitored participants by telephone and on average three home visits. Primary outcome measures were functional health and instrumental activities of daily living disability. Secondary outcomes were acute hospital admittance (time until), institutionalization, and mortality.
  
  
  RESULTS
  We found no significant differences between intervention and usual care group on any of the outcome measures. Predefined subgroup analyses revealed a higher risk of hospital admission for persons with poor health in the intervention group.
  
  
  CONCLUSIONS
  We could not demonstrate preventive effects of home visits by nurses in vulnerable older persons. Hospital admissions increased in the frailest group. The search for effective interventions for vulnerable persons requires further investigation. Future efforts may focus on improved integrated approaches.
authors.affiliation: Department of General Practice, EMGO Institute, VU University Medical Center Amsterdam, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands. hpj.vanhout@vumc.nl
authors.forename: Hein P J
authors.initials: HP
authors.lastname: van Hout
authors.forename: Aaltje P D
authors.initials: AP
authors.lastname: Jansen
authors.forename: Harm W J
authors.initials: HW
authors.lastname: van Marwijk
authors.forename: Marieke
authors.initials: M
authors.lastname: Pronk
authors.forename: Dinnus F
authors.initials: DF
authors.lastname: Frijters
authors.forename: Giel
authors.initials: G
authors.lastname: Nijpels
mesh_terms: D000203:Activities of Daily Living; D000369:Aged, 80 and over; D005260:Female; D016330:Frail Elderly; D015577:Geriatric Assessment; D006299:Health Services for the Aged; D006304:Health Status; D006701:Home Nursing; D006760:Hospitalization; D006801:Humans; D007326:Institutionalization; D008297:Male; D009026:Mortality; D017063:Outcome Assessment, Health Care; D012307:Risk Factors; D012959:Socioeconomic Factors