title: [Effects of multi-genes for reproductive traits in Tibet pig].
abstract: Tibet pig is a unique native breed in the plateau of China, which has good adaptation to the harsh climate of high land and resistance to diseases and crude feeding. However, its reproductive rate is low. The objectives of this study were to search for the polymorphisms of estrogen receptor (ESR), follicle-stimulating hormone (FSHb), prolactin receptor (PRLR), and retinol binding protein 4 (RBP4) in Tibet pig and to analyze the effects of these variants and their combination genotypes on reproductive traits. The results showed that the effects of FSHb, ESR, and PRLR genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively. There were two genotypes for RBP4 gene in Tibet pig, which did not have significant effect on the reproductive traits. The optical genotype of FSHb-ESR-PRLR is BB-BB-AA, which is more effective on reproductive traits than any single gene in Tibet pig.
authors.affiliation: College of Animal Science and Technology, China Agricultural University, Bejing 100193, China. liuxuantc@163.com
authors.forename: Xuan
authors.initials: X
authors.lastname: Liu
authors.forename: Yangzom
authors.initials: Y
authors.lastname: Chamba
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.forename: Yao
authors.initials: Y
authors.lastname: Ling
authors.forename: Xue-Dong
authors.initials: XD
authors.lastname: Gu
authors.forename: Ke-Liang
authors.initials: KL
authors.lastname: Wu
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
mesh_terms: D000483:Alleles; D000818:Animals; D005260:Female; D037201:Follicle Stimulating Hormone, beta Subunit / Q000235:genetics*; D005787:Gene Frequency; D005838:Genotype; D008098:Litter Size / Q000235:genetics; D008297:Male; D011110:Polymorphism, Genetic; D011960:Receptors, Estrogen / Q000235:genetics*; D011981:Receptors, Prolactin / Q000235:genetics*; D012098:Reproduction / Q000235:genetics; D054839:Retinol-Binding Proteins, Plasma / Q000235:genetics*; D013552:Swine / Q000235:genetics*; D018609:Tibet
chemical_list: D037201:Follicle Stimulating Hormone, beta Subunit; D011960:Receptors, Estrogen; D011981:Receptors, Prolactin; D054839:Retinol-Binding Proteins, Plasma