Simulation studies of instrumental artifacts on spin I=1 double quantum filtered NMR spectroscopy.
We report on the results of a simulation based study of the effect of various experimental artifacts for spin I=1 double quantum filtered NMR. The simulation captures the effects of static field inhomogeneity, finite pulse widths, phase errors, transients and radio frequency field inhomogeneity. We simulated the spectral distortions introduced under these errors for four, eight and sixteen step phase cycles that are well known in the NMR community. The dominating pulse errors are radio frequency field inhomogeneity and antisymmetric pulse transients. These errors result in the reduction of signal intensity as well as an introduction of distortions in the detected double quantum filtered spectrum. Using the simulation tool we studied the improvement one obtains when implementing a sixteen step phase cycle over a four step phase cycle. The results indicate that implementing a sixteen step phase cycle over an eight or four step phase cycle does not result in a significant reduction in the DQF intensity loss, or reduction in spectral distortions for antisymmetric transients.
Sun
Cheng
C
Brooklyn College, Department of Physics, 2900 Bedford Avenue, Brooklyn, NY 11210, United States.
Boutis
Gregory S
GS
D000465:Algorithms; D016477:Artifacts; D003627:Data Interpretation, Statistical; D004574:Electromagnetic Fields; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000706:statistics & numerical data*; D011789:Quantum Theory; D013113:Spin Labels
D013113:Spin Labels
J Magn Reson. 2004 Sep;170(1):22-41
15324755
Magn Reson Med. 2002 Aug;48(2):322-30
12210941
Biopolymers. 2004 Sep;75(1):46-59
15307197
J Magn Reson. 1999 Apr;137(2):295-310
10089163
Biophys J. 1997 Sep;73(3):1198-204
9284287
J Magn Reson. 2010 Feb;202(2):239-44
20004122
J Magn Reson. 1997 Nov;129(1):98-104
9405221
Magn Reson Med. 2007 Jun;57(6):990-9
17534920
NMR Biomed. 2001 Apr;14(2):112-32
11320537
NMR Biomed. 2006 Nov;19(7):877-93
17075957
J Magn Reson. 2011 Dec;213(2):276-94
22152348