title: Dissecting the Finnish male uniformity: the value of additional Y-STR loci.
abstract: The forensic use of Y-chromosomal markers can be hampered by reduced diversity and geographical subdivision in some populations. In Finland both of these confounding factors are well documented, but it is also shown that increase of data could resolve or at least alleviate these problems. In order to increase the forensic usability of Y-chromosomal data in Finland, we have here evaluated the diversity at a number of additional Y-STRs. A seven Y-STR locus panel ("FY7": DYS449, DYS460, DYS505, DYS522, DYS576, DYS612 and DYS627) was found to reveal higher diversity levels among Finns than the substantially larger commercial multiplexes commonly in use. The Y-STR data augmented with the FY7 panel shows substantially higher discrimination capacity and lower levels of geographical structure among Finns. Amplifiable in one multiplex, this set of loci offers an informative and easy-to-use supplementary for the commercial Y-STR kits.
authors.affiliation: Laboratory of Forensic Biology, Hjelt Institute, P.O. Box 40, 00014 University of Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Hedman
authors.forename: A M
authors.initials: AM
authors.lastname: Neuvonen
authors.forename: A
authors.initials: A
authors.lastname: Sajantila
authors.forename: J U
authors.initials: JU
authors.lastname: Palo
mesh_terms: D041322:Chromosomes, Human, Y; D005387:Finland; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D009154:Mutation