What is the significance of solitary bony abnormalities on bone scintigrams of children with malignancy?
This investigation was undertaken to evaluate the significance of solitary bony abnormalities on bone scintigrams of children with known or suspected malignancy. A total of 215 bone scans were performed in 183 children in order to look for possible metastasis over a 10-year period. Forty-nine scans (22.8%) were found to have single lesions, of which 18 were due to uptake at the primary site and were excluded from further consideration. Of the remaining 31 lesions, 13 (41.9%) were confirmed as metastases, 17 lesions were proved to be benign, and 1 indeterminate. Solitary hot spots in children with known or suspected malignancy are common and therefore have to be taken seriously due to their higher malignant potential.
Freeman
Susan J
SJ
Department of Radiology, Addenbrookes' Hospital, Cambridge, England, UK.
Sonoda
Luke I
LI
Seshadri
Nagabhushan
N
Howard
William
W
Set
Patricia A K
PA
Balan
Kottekkattu K
KK
D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009362:Neoplasm Metastasis / Q000175:diagnosis*; D011877:Radionuclide Imaging / Q000379:methods; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate