Colloquium paper: working toward a synthesis of archaeological, linguistic, and genetic data for inferring African population history.
Although Africa is the origin of modern humans, the pattern and distribution of genetic variation and correlations with cultural and linguistic diversity in Africa have been understudied. Recent advances in genomic technology, however, have led to genomewide studies of African samples. In this article, we discuss genetic variation in African populations contextualized with what is known about archaeological and linguistic variation. What emerges from this review is the importance of using independent lines of evidence in the interpretation of genetic and genomic data in the reconstruction of past population histories.
Scheinfeldt
Laura B
LB
Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Soi
Sameer
S
Tishkoff
Sarah A
SA
D000349:Africa; D001106:Archaeology / Q000379:methods; D005075:Biological Evolution; D004641:Emigration and Immigration; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D043322:Lactase / Q000235:genetics; D007802:Language; D008037:Linguistics; D018895:Microsatellite Repeats / Q000235:genetics; D008957:Models, Genetic
D043322:Lactase
Science. 2009 May 22;324(5930):1035-44
19407144
Hum Genet. 2005 Aug;117(4):366-75
15928903
Genetics. 2002 May;161(1):447-59
12019257
Am J Phys Anthropol. 2002 Oct;119(2):175-85
12237937
Hum Biol. 2006 Feb;78(1):9-27
16900879
Ann Hum Genet. 2001 Jan;65(Pt 1):43-62
11415522
PLoS Genet. 2007 Nov;3(11):e185
18039031
PLoS Biol. 2004 Oct;2(10):e286
15361935
Am J Phys Anthropol. 1992 Oct;89(2):159-81
1443092
Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10597-602
10485871
Am J Hum Genet. 2002 May;70(5):1197-214
11910562
Science. 2002 Feb 15;295(5558):1278-80
11786608
Science. 2004 Dec 3;306(5702):1680; author reply 1680
15576591
Am J Hum Genet. 2002 Jan;70(1):265-8
11719903
Annu Rev Genomics Hum Genet. 2008;9:403-33
18593304
Hum Genet. 2009 Jan;124(6):579-91
19034520
J Hum Evol. 2000 Nov;39(5):453-563
11102266
Nature. 2005 Feb 17;433(7027):733-6
15716951
Annu Rev Genet. 2003;37:197-219
14616060
Science. 2008 Feb 22;319(5866):1100-4
18292342
Hum Biol. 2003 Dec;75(6):941-9
15018041
Am J Hum Genet. 2004 May;74(5):1023-34
15069642
Am J Hum Genet. 2004 Jun;74(6):1102-10
15106124
Nature. 1987 Jan 1-7;325(6099):31-6
3025745
BMC Evol Biol. 2009 Mar 23;9:63
19309521
Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10693-8
18678889
PLoS Genet. 2009 Apr;5(4):e1000448
19360089
Nature. 1989 Apr 27;338(6218):756-8
2541339
Hum Immunol. 2001 Sep;62(9):937-48
11543896
Am Nat. 2004 Feb;163(2):212-26
14970923
Science. 2002 Apr 12;296(5566):336-9
11951043
Eur J Hum Genet. 2010 Jul;18(7):800-7
20051990
Mol Biol Evol. 2006 Aug;23(8):1628-41
16754639
Mol Biol Evol. 2007 Mar;24(3):757-68
17194802
J Hum Evol. 2001 Dec;41(6):631-78
11782112
Nat Genet. 2007 Jan;39(1):31-40
17159977
Syst Biol. 2005 Aug;54(4):513-26
16051587
Hum Genet. 2004 Oct;115(5):439-47
15340834
Nature. 1986 Dec 4-10;324(6096):453-5
3097556
PLoS Genet. 2008 Jan;4(1):e19
18208337
Proc Biol Sci. 2007 Jun 7;274(1616):1377-85
17412685
Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5836-40
7597038
Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):786-91
20080753
Curr Biol. 2003 Mar 18;13(6):464-73
12646128
Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9381-6
16772383
Hum Biol. 2001 Feb;73(1):17-55
11332644
Hum Genet. 2007 Feb;120(6):779-88
17120047
Am J Hum Genet. 2001 Sep;69(3):615-28
11481588
Eur J Hum Genet. 2007 Nov;15(11):1183-5
17700630
Am J Hum Genet. 2008 Jan;82(1):57-72
18179885
Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1596-601
18216239
Nature. 2007 Oct 18;449(7164):851-61
17943122
Hum Biol. 2004 Feb;76(1):55-75
15222680
Am J Phys Anthropol. 2008 Nov;137(3):316-23
18618658
Mol Biol Evol. 2009 Jul;26(7):1581-9
19369595
Nature. 2000 Dec 7;408(6813):708-13
11130070
Ann Hum Genet. 2007 Jul;71(Pt 4):433-52
17233755
Am J Phys Anthropol. 2000 Apr;111(4):557-72
10727973
Genetics. 2000 Jun;155(2):945-59
10835412
Nat Genet. 2002 Feb;30(2):233-7
11788828
Nat Genet. 2000 Nov;26(3):358-61
11062480
Mol Biol Evol. 2009 Dec;26(12):2765-73
19729424
Nature. 2003 Jun 12;423(6941):747-52
12802333
Am J Hum Genet. 1999 Sep;65(3):829-46
10441590
Am J Hum Genet. 2002 Nov;71(5):1082-111
12395296
Ann Hum Genet. 2001 Sep;65(Pt 5):439-58
11806853
Mol Biol Evol. 2008 Mar;25(3):517-25
18093995
Nature. 1993 May 20;363(6426):252-5
8387643
Monogr Popul Biol. 1981;16:1-388
7300842
Nature. 2003 Dec 18;426(6968):789-96
14685227
Am J Phys Anthropol. 1999 Nov;110(3):243-70
10516560
Eur J Hum Genet. 2005 Jul;13(7):867-76
15856073
Genetics. 2007 Dec;177(4):2195-207
18073427
Am J Hum Genet. 2008 May;82(5):1130-40
18439549
Mol Biol Evol. 2007 Oct;24(10):2180-95
17656633