title: Validity of the telephone interview for cognitive status (TICS) and modified TICS (TICSm) for mild cognitive imparment (MCI) and dementia screening.
abstract: This study aimed to validate the TICS and modified TICS (TICSm) in Korean elderly population and to compare MCI and dementia screening ability between TICS and TICSm. TICS and TICSm were administered to 70 cognitively normal (CN), 75 MCI, and 85 dementia subjects, with mini-mental state examination (MMSE) and other cognitive and functional measures. TICS and TICSm scores were highly correlated with other global cognitive and functional scores. The CN vs. dementia discrimination ability of both instruments was as excellent as that of MMSE (sensitivity/specificity at optimal cutoff: 87.1/90.1 for TICS; 88.2/90.0 for TICSm). Although their CN vs. MCI discrimination performances were comparable to that of MMSE, they were far from perfect (sensitivity/specificity: 69.3/68.6 for TICS; 73.3/67.1 for TICSm). There was no significant difference in dementia or MCI screening accuracy between TICS and TICSm. Both of them also showed high test-retest reliability. Our findings indicate that TICS and TICSm are reliable and as valid as MMSE in regard of screening cognitively impaired elderly. In terms of the comparison between TICSm and TICS, however, TICSm has little advantage over TICS for screening dementia and even MCI, in spite of longer administration time and more efforts required.
authors.affiliation: Interdisciplinary Program for Cognitive Science, Seoul National University, 599 Kwanak-ro, Kwanak-gu, Seoul 151-742, Republic of Korea.
authors.forename: Eun Hyun
authors.initials: EH
authors.lastname: Seo
authors.forename: Dong Young
authors.initials: DY
authors.lastname: Lee
authors.forename: Shin Gyeom
authors.initials: SG
authors.lastname: Kim
authors.forename: Ki Woong
authors.initials: KW
authors.lastname: Kim
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Kim
authors.forename: Bong Jo
authors.initials: BJ
authors.lastname: Kim
authors.forename: Moon-Doo
authors.initials: MD
authors.lastname: Kim
authors.forename: Seong Yoon
authors.initials: SY
authors.lastname: Kim
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Kim
authors.forename: Jeong-Lan
authors.initials: JL
authors.lastname: Kim
authors.forename: Jee Wook
authors.initials: JW
authors.lastname: Kim
authors.forename: Seok Woo
authors.initials: SW
authors.lastname: Moon
authors.forename: Joon Hyuck
authors.initials: JH
authors.lastname: Park
authors.forename: Seung-Ho
authors.initials: SH
authors.lastname: Ryu
authors.forename: Jong Choul
authors.initials: JC
authors.lastname: Yoon
authors.forename: Nam Jin
authors.initials: NJ
authors.lastname: Lee
authors.forename: Chang Uk
authors.initials: CU
authors.lastname: Lee
authors.forename: Jin Hyeong
authors.initials: JH
authors.lastname: Jhoo
authors.forename: Ll Han
authors.initials: LH
authors.lastname: Choo
authors.forename: Jong Inn
authors.initials: JI
authors.lastname: Woo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards; D015203:Reproducibility of Results; D056910:Republic of Korea; D012680:Sensitivity and Specificity