Integrating clinical trial imaging data resources using service-oriented architecture and grid computing.
Clinical trials which use imaging typically require data management and workflow integration across several parties. We identify opportunities for all parties involved to realize benefits with a modular interoperability model based on service-oriented architecture and grid computing principles. We discuss middleware products for implementation of this model, and propose caGrid as an ideal candidate due to its healthcare focus; free, open source license; and mature developer tools and support.
El-Ghatta
Stefan Baumann
SB
Biomarker Development/Clinical Imaging, Novartis Institutes for BioMedical Research, Lichtstrasse 35, 4056, Basel, Switzerland. stefan.baumann@novartis.com
Cladé
Thierry
T
Snyder
Joshua C
JC
D002986:Clinical Trials as Topic; D019295:Computational Biology; D003628:Database Management Systems; D003952:Diagnostic Imaging; D006295:Health Resources; D006801:Humans; D033181:Information Dissemination; D020407:Internet; D008490:Medical Informatics; D018511:Systems Integration
J Am Med Inform Assoc. 2008 Mar-Apr;15(2):138-49
18096909
Clin Pharmacol Ther. 2008 Jul;84(1):69-74
18563070