title: Relationships in glaucoma patients between standard vision tests, quality of life, and ability to perform daily activities.
abstract: OBJECTIVE
  To determine the relationships among three methods of assessing visual loss caused by glaucoma: (1) standard clinical tests of vision, (2) self-reported quality of life, and (3) the ability to perform activities of daily living.
  
  
  METHODS
  One hundred and ninety two glaucoma patients with a full range of glaucomatous visual loss were selected from the Glaucoma Service of Wills Eye Institute. Subjects were evaluated clinically by visual acuity, contrast sensitivity, visual field, stereopsis, the Disc Damage Likelihood Scale, and intraocular pressure. Subjects were evaluated subjectively by the 25-item National Eye Institute's Visual Functioning Questionnaire (NEI-VFQ-25) and objectively by a performance-based measure of visual function, the Assessment of Disability Related to Vision (ADREV). Statistical analysis, including Spearman coefficients, was performed on the data from the clinical measures, NEI-VFQ-25, and ADREV.
  
  
  RESULTS
  The clinical tests had higher correlations with ADREV than with the NEI-VFQ-25. There was a moderate, but not strong, connection between how patients rated their own visual ability with how they performed when objectively tested.
  
  
  CONCLUSIONS
  ADREV provides valid estimates of how visual loss due to glaucoma affects the ability to perform activities of daily living. Performance-based testing and quality of life evaluations are both independently important measures of health, which are related, but by no means the same.
authors.affiliation: Glaucoma Service, Wills Eye Institute of Jefferson Medical College, Philadelphia, PA 1910, USA. jesse_richman@yahoo.com
authors.forename: Jesse
authors.initials: J
authors.lastname: Richman
authors.forename: Luciano L
authors.initials: LL
authors.lastname: Lorenzana
authors.forename: Dara
authors.initials: D
authors.lastname: Lankaranian
authors.forename: Jyoti
authors.initials: J
authors.lastname: Dugar
authors.forename: Jason R
authors.initials: JR
authors.lastname: Mayer
authors.forename: Sheryl S
authors.initials: SS
authors.lastname: Wizov
authors.forename: George L
authors.initials: GL
authors.lastname: Spaeth
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003867:Depth Perception; D004185:Disability Evaluation; D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000175:diagnosis*; D014787:Vision Tests; D014792:Visual Acuity; D014794:Visual Fields; D055815:Young Adult