title: New N-acyl taurine from the sea urchin Glyptocidaris crenularis.
abstract: A new N-acyl taurine (1), together with a new natural product, l-(beta-D-ribofuranosyl)-1,2,4-triazole (4), and two known compounds (2 and 3), were isolated from the sea urchin, Glyptocidaris crenularis. The new N-acyl taurine was elucidated as 2-(5R,15S-dihydroxyeicosanoylamino) ethanesulfonic acid on the basis of spectroscopic (NMR, MS) analyses and the modified Mosher ester method. Compound 2 showed significant toxicity against brine shrimp larvae.
authors.affiliation: Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Zhou
authors.forename: Tunhai
authors.initials: T
authors.lastname: Xu
authors.forename: Kewei
authors.initials: K
authors.lastname: Wen
authors.forename: Xian-Wen
authors.initials: XW
authors.lastname: Yang
authors.forename: Shi-Hai
authors.initials: SH
authors.lastname: Xu
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D006893:Hydroxyeicosatetraenoic Acids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012617:Sea Urchins / Q000737:chemistry*; D013654:Taurine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: C551885:2-(5,15-dihydroxyeicosanoylamino)ethanesulfonic acid; D006893:Hydroxyeicosatetraenoic Acids; D013654:Taurine