Differentiating between benign and non-benign obesity: look at the liver.
Several recent experimental and epidemiological studies suggest that some forms of obesity may be benign and do not carry high risk of development of diabesity related disorders. This commentary discusses the available data supporting this concept, as well as the pathophysiological mechanisms.
Poupon
R
R
Hôpital Saint-Antoine, AP-HP, UPMC, Faculté de Médecine, 184, rue du Faubourg-Saint-Antoine, 75012 Paris cedex, France. raoul.poupon@gmail.com
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D015415:Biomarkers; D005234:Fatty Liver / Q000378:metabolism*; D006306:Health Surveys; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D008099:Liver; D024821:Metabolic Syndrome / Q000378:metabolism; D009765:Obesity / Q000378:metabolism*; D005723:gamma-Glutamyltransferase / Q000097:blood
D015415:Biomarkers; D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase