title: Irritable bowel syndrome in haemodialysis: Prevalence, link with quality of life and depression.
abstract: OBJECTIVE
  Health-related quality of life (HRQOL) is decreased in haemodialysis (HD) patients. Irritable bowel syndrome (IBS) is highly prevalent in general population. This study evaluated the prevalence of IBS and its association with HRQOL and depression in HD.
  
  
  METHODS
  Sociodemographic and laboratory variables were recorded. Severity of depressive symptoms and HRQOL were assessed by the Beck Depression Inventory (BDI) and Short Form 36 (SF-36), respectively. Diagnosis of IBS was based on Rome II criteria.
  
  
  RESULTS
  Among 236 patients 69 (29.2%) had IBS. Patients with IBS had lower SF-36 scores and had higher depressive symptoms than patients without IBS. Presence of IBS was associated with sleep disturbance (odds ratio (OR) = 2.012; P = 0.045), physical component summary score (OR = 0.963, P = 0.029), mental component summary score (OR = 0.962, P = 0.023), BDI score (OR = 1.040, P = 0.021) and albumin (OR = 0.437, P = 0.01).
  
  
  CONCLUSIONS
  IBS is highly prevalent in HD patients. Presence of IBS is closely related with HRQOL and depression.
authors.affiliation: Gülhane School of Medicine, Department of Nephrology, Ankara. afsarbrs@yahoo.com
authors.forename: Baris
authors.initials: B
authors.lastname: Afsar
authors.forename: Rengin
authors.initials: R
authors.lastname: Elsurer
authors.forename: M Ilker
authors.initials: MI
authors.lastname: Yilmaz
authors.forename: Tayfun
authors.initials: T
authors.lastname: Eyileten
authors.forename: Müjdat
authors.initials: M
authors.lastname: Yenicesu
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D007674:Kidney Diseases / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D006435:Renal Dialysis / Q000523:psychology*; D018570:Risk Assessment; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000209:etiology; D014421:Turkey / Q000453:epidemiology
chemical_list: D015415:Biomarkers; D012709:Serum Albumin