title: Primary myxoma of the lung.
abstract: A case of primary myxoma of the lung is presented. The patient is a 70-year-old woman who presented with a history of dyspnea, cough, and mild chest discomfort. Chest radiographic studies disclosed the presence of a well-marginated nodule in the left upper lobe. A wedge resection of the tumor mass was performed. The specimen contained a tan-gray, soft, well-circumscribed tumor nodule of approximately 1.8 cm in greatest dimension. Histologically, the tumor was characterized by a well-demarcated lesion, composed of loose spindle and stellate cells embedded in a myxoid matrix, containing thin-walled vessels. Immunohistochemical studies showed the cell to be negative for S-100, keratin, desmin, smooth muscle actin, and HMB-45. Vimentin stain showed positive staining in some of the stellate cells. No evidence of recurrence or metastatic disease was observed after 18 months.
authors.affiliation: Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. nkalhor@mdanderson.org
authors.forename: Neda
authors.initials: N
authors.lastname: Kalhor
authors.forename: Edith M
authors.initials: EM
authors.lastname: Marom
authors.forename: Cesar A
authors.initials: CA
authors.lastname: Moran
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009232:Myxoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D014746:Vimentin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D014746:Vimentin