title: Mean platelet volume: a new predictor in confirming acute appendicitis diagnosis.
abstract: The purpose of this study was to investigate the diagnostic value of mean platelet volume (MPV) in acute appendicitis (AA).
  
  
  METHODS
  Our study was carried out in 206 healthy control groups and 226 patients who had a preliminary diagnosis of AA.
  
  
  RESULTS
  A statistically significant decrease in MPV was noted in patients with AA compared with healthy controls (P < .001). The best MPV level cutoff point for AA was 7.6 fL, with a sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 73%, 84%, 84%, and 74%, respectively.
  
  
  CONCLUSIONS
  As the MPV value is included in the complete blood count (CBC) analysis, it increases the sensitivity and NPVs of white blood cell (WBC) in AA diagnosis without the need for extra analyses, loss of time, or cost increase. Therefore, we believe that the MPV value should also be taken into consideration along with the WBC in every patient with suspected AA.
authors.affiliation: Department of General Surgery and Burn Unit, Erzurum Region Education and Research Hospital, Erzurum, Turkey. yavuzalbayrakdr@gmail.com
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Albayrak
authors.forename: Ayse
authors.initials: A
authors.lastname: Albayrak
authors.forename: Fatih
authors.initials: F
authors.lastname: Albayrak
authors.forename: Rahsan
authors.initials: R
authors.lastname: Yildirim
authors.forename: Belkiz
authors.initials: B
authors.lastname: Aylu
authors.forename: Abdullah
authors.initials: A
authors.lastname: Uyanik
authors.forename: Esref
authors.initials: E
authors.lastname: Kabalar
authors.forename: Ibrahim C
authors.initials: IC
authors.lastname: Güzel
mesh_terms: D000208:Acute Disease; D000328:Adult; D001064:Appendicitis / Q000097:blood* / Q000175:diagnosis*; D001792:Blood Platelets / Q000473:pathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male