Mutations for the people.
Similar cancer types may nevertheless differ widely in the genetic mutations they carry. In this Closeup, Kristensen and Borresen-Dale discuss how identifying these mutations can define which therapy is most likely to succeed in eliminating the cancerous cells and how the methodology developed by Dias-Santagata et al and described in this issue, is an important step in making mutation screening a reality in the clinical practice worldwide.
Kristensen
Vessela
V
Institute for Cancer Research, Oslo, Norway. v.n.kristensen@medisin.uio.no
Borresen-Dale
Anne-Lise
AL
D004252:DNA Mutational Analysis; D005838:Genotype; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics* / Q000628:therapy
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