title: [Allopurinol-induced hypersensitivity syndrome resulting in death].
abstract: The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.
authors.affiliation: Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Hannover, Germany. Laurisch.Soeren@mh-hannover.de
authors.forename: Sören
authors.initials: S
authors.lastname: Laurisch
authors.forename: Maren
authors.initials: M
authors.lastname: Jaedtke
authors.forename: Reyhan
authors.initials: R
authors.lastname: Demir
authors.forename: Sajoscha A
authors.initials: SA
authors.lastname: Sorrentino
authors.forename: Jan T
authors.initials: JT
authors.lastname: Kielstein
authors.forename: Hans-Oliver
authors.initials: HO
authors.lastname: Rennekampff
authors.forename: Peter M
authors.initials: PM
authors.lastname: Vogt
authors.forename: Gerd P
authors.initials: GP
authors.lastname: Meyer
authors.forename: Martin
authors.initials: M
authors.lastname: Fuchs
authors.forename: Gunnar
authors.initials: G
authors.lastname: Klein
authors.forename: Hartmut
authors.initials: H
authors.lastname: Drexler
authors.forename: Bernhard
authors.initials: B
authors.lastname: Schieffer
authors.forename: L Christian
authors.initials: LC
authors.lastname: Napp
mesh_terms: D000368:Aged; D000493:Allopurinol / Q000633:toxicity*; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D017809:Fatal Outcome; D006073:Gout / Q000188:drug therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D012008:Recurrence; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D000493:Allopurinol
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