Should We Still be Performing Vasectomies?
Longterm safety of vasectomy has been questioned, based on the possibility of sperm antigens causing an antibody response. The point at which the antigens enter the circulation is unknown. Animal experiments have shown atherosclerosis as a result of antibody production, but evidence in man is still equivocal. Nonetheless, the family physician is obliged to inform patients of possible postoperative complications, but to avoid overinterpretation of a still controversial problem.
Smith
R K
RK
Science. 1978 Aug 11;201(4355):538-41
96532
J Exp Med. 1976 Feb 1;143(2):382-404
129498
Fertil Steril. 1972 Sep;23(9):640-3
5050294
Am J Epidemiol. 1978 Sep;108(3):176-80
707485
Sci Am. 1980 Nov;243(5):53-9
7423181
Br Med J. 1976 Mar 13;1(6010):621-2
1252850
Lancet. 1981 Jan 3;1(8210):13-5
6109049
Tissue Antigens. 1979 Aug;14(2):115-39
386565
Contraception. 1973 Aug;8(2):147-64
4797560
Arch Pathol. 1974 Jul;98(1):9-16
4208401
Fertil Steril. 1977 Jun;28(6):655-7
558921
J Clin Invest. 1980 Jan;65(1):15-25
6765957
Fertil Steril. 1979 Sep;32(3):253-60
114428
Arch Androl. 1978 May;1(3):249-55
310663
Clin Exp Immunol. 1979 Oct;38(1):31-36
393440
Clin Exp Immunol. 1975 Jul;21(1):65-74
1102162