title: Efficacy of bleeding control using a large amount of highly diluted vasopressin in laparoscopic treatment for interstitial pregnancy.
abstract: OBJECTIVE
  We sought to report the safety and effectiveness of bleeding control using a large amount of highly diluted vasopressin in laparoscopic management of interstitial pregnancy.
  
  
  METHODS
  This was an uncontrolled retrospective review of 20 patients who were laparoscopically treated for interstitial pregnancy using a large amount of highly diluted vasopressin. For hemostasis, 1 ampule of vasopressin was diluted in 1000 mL of normal saline (1000-fold) and 150-250 mL of diluted vasopressin was injected in the uterus below interstitial pregnancy.
  
  
  RESULTS
  Mean patient age and gestational age was 33.5 years and 6.7 weeks, respectively. Mean blood loss was 24 mL. The mean serum human chorionic gonadotropin level was 10,950, 4065, and 959 mIU/mL on the day of operation and postoperative days 1 and 4, respectively.
  
  
  CONCLUSIONS
  Laparoscopic management of interstitial pregnancy using a large amount of highly diluted vasopressin is safe and effective in hemostasis with minimal blood loss and no complications.
authors.affiliation: Department of Obstetrics and Gynecology, Center for Minimally Invasive Surgery, Good Moonhwa Hospital, 899-8 Beomil2-dong, Busan, Korea. moonhwas@moonhwa.or.kr
authors.forename: Hwa Sook
authors.initials: HS
authors.lastname: Moon
authors.forename: Sang Gab
authors.initials: SG
authors.lastname: Kim
authors.forename: Gun Sik
authors.initials: GS
authors.lastname: Park
authors.forename: Jin Kuk
authors.initials: JK
authors.lastname: Choi
authors.forename: Ja Seong
authors.initials: JS
authors.lastname: Koo
authors.forename: Bo Sun
authors.initials: BS
authors.lastname: Joo
mesh_terms: D000328:Adult; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000601:surgery*; D012189:Retrospective Studies; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*; D014667:Vasopressins / Q000008:administration & dosage*
chemical_list: D014662:Vasoconstrictor Agents; D014667:Vasopressins