[Microhemocirculation and its correction in duodenal ulcer during period of rehabilitation].
The background of this research is to study morphological and functional microcirculatory channel condition with duodenum ulcer in the period of rehabilitation against the background of regular antiulcer therapy (1 group) and further treatment using Vazonit (2 group) in clinical conditions. EDU in animals results in marked microcirculatory disease in duodenum depending on the time of ulcer process development. Hypoxia is to be the significant factor associated with capillary stases, venous congestion. Blood flow impairment in organ results in metabolic damages of tissue structures. The results obtained are evidence of significant correction of microcirculatory channel state, improvement of regeneration and reparation processes. Vazonit improves the disorder of microcirculation and theological blood properties, restoring of macro and microangiopathy changes of hemocirculatory channel.
Parpibaeva
D A
DA
Zakirkhodzhaev
Sh Ia
ShIa
Sagatov
T A
TA
Shakirova
D T
DT
Narziev
N M
NM
D000328:Adult; D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004381:Duodenal Ulcer / Q000473:pathology / Q000503:physiopathology / Q000534:rehabilitation*; D004386:Duodenum / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects*; D055806:Microvessels / Q000187:drug effects / Q000473:pathology; D008875:Middle Aged; D009278:Naphazoline / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats; D016896:Treatment Outcome
D000890:Anti-Infective Agents; D000897:Anti-Ulcer Agents; D009278:Naphazoline