One-pot cascade Michael-Michael-aldol condensation for diastereoselective synthesis of nitro-substituted cyclohexanes.
A one-pot reaction of nitroalkenes and enones was developed for the preparation of nitro-vinyl-substituted cyclohexanes, which could be simply converted into poly-N-heterocycles.
Chen
Yunfeng
Y
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, USA.
Zhong
Cheng
C
Sun
Xiaohua
X
Akhmedov
Novruz G
NG
Petersen
Jeffrey L
JL
Shi
Xiaodong
X
D000475:Alkenes / Q000737:chemistry; D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry; D013237:Stereoisomerism
D000475:Alkenes; D003510:Cyclohexanes; D007659:Ketones; D009574:Nitro Compounds