title: Current concepts in the classification, diagnosis and treatment of vascular anomalies.
abstract: Patients with extended vascular anomalies may suffer from significant aesthetic and functional impairment and represent a challenge to therapeutic planning, which is best met by an interdisciplinary concept. In agreement with the International Society for the Study of Vascular Anomalies (ISSVA), vascular lesions are classified into haemangiomas as proliferating endothelial tumours on the one hand and congenital vascular malformations on the other. According to the preponderant vascular channels and hemodynamic characteristics, malformations are subdivided into low flow (venous, lymphatic and capillary) lesions and high-flow malformations. Diagnostic imaging should be targeted at the specific structural and functional informations required for treatment planning. The imaging modality of choice to provide these informations is magnetic resonance imaging (MRI) supplemented by magnetic resonance angiography (MRA) with high spatial and temporal resolution. Treatment indications for haemangiomas depend on the proliferative behaviour of the lesion and comprise beta-blockers in order to induce involution as well as cryotherapy, laser and open surgery. Interventional radiological procedures have evolved as an essential element in an interdisciplinary treatment plan for vascular malformations and include percutaneous sclerotherapy with ethanol and OK-432 for venous and lymphatic malformations and transarterial embolization for high-flow lesions.
authors.affiliation: Department of Diagnostic and Interventional Neuroradiology, Radiological Clinic, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany. ulrike.ernemann@med.uni-tuebingen.de
authors.forename: Ulrike
authors.initials: U
authors.lastname: Ernemann
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kramer
authors.forename: Stephan
authors.initials: S
authors.lastname: Miller
authors.forename: Sotirios
authors.initials: S
authors.lastname: Bisdas
authors.forename: Hans
authors.initials: H
authors.lastname: Rebmann
authors.forename: Helmut
authors.initials: H
authors.lastname: Breuninger
authors.forename: Christine
authors.initials: C
authors.lastname: Zwick
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hoffmann
mesh_terms: D000792:Angiography / Q000379:methods*; D001808:Blood Vessels / Q000002:abnormalities*; D006391:Hemangioma / Q000145:classification / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D014656:Vascular Surgical Procedures / Q000379:methods*