title: What is the best method for brain protection in surgery of the aortic arch? Selective antegrade cerebral perfusion.
abstract: Despite considerable progress in the operative management of lesions involving the transverse aortic arch, replacement of this portion of the vessel remains a surgical challenge and is still associated with mortality and morbidity. This situation is due not only to the technical difficulties of the procedure but, often, to the unsatisfactory preservation of the integrity of the central nervous system during the period of arch exclusion. The techniques of cerebral protection during surgery of the aortic arch can be divided into those aimed at suppressing the metabolic demand of the central nervous system and those aimed at maintaining the metabolic supply during the time of exclusion of the cerebral vessels. Whichever technique is used, it must maintain the normal metabolism of the central nervous system or, at least, allow restoration of the physiologic conditions of its function. In this regard, selective antegrade cerebral perfusion has demonstrated experimentally and clinically its superiority over the other proposed protective techniques.
authors.affiliation: Department of Cardiovascular Surgery, Zayed Military Hospital, Abu Dhabi, UAE. jean.bachet@dms.mil.ae
authors.forename: Jean
authors.initials: J
authors.lastname: Bachet
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D050792:Circulatory Arrest, Deep Hypothermia Induced / Q000379:methods*; D006801:Humans; D010477:Perfusion / Q000379:methods*; D020521:Stroke / Q000209:etiology / Q000517:prevention & control*; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000379:methods*