title: Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA).
abstract: OBJECTIVE
  We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea.
  
  
  METHODS
  In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht(2)) (kg/m(2)) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area >or=100 cm(2).
  
  
  RESULTS
  The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht(2); however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% CI 4.45-15.40]) than the obese (5.51 [2.81-10.80]) or sarcopenic group (2.64 [1.08-6.44]).
  
  
  CONCLUSIONS
  SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Soo
authors.initials: S
authors.lastname: Lim
authors.forename: Jung Hee
authors.initials: JH
authors.lastname: Kim
authors.forename: Ji Won
authors.initials: JW
authors.lastname: Yoon
authors.forename: Seon Mee
authors.initials: SM
authors.lastname: Kang
authors.forename: Sung Hee
authors.initials: SH
authors.lastname: Choi
authors.forename: Young Joo
authors.initials: YJ
authors.lastname: Park
authors.forename: Ki Woong
authors.initials: KW
authors.lastname: Kim
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Lim
authors.forename: Kyong Soo
authors.initials: KS
authors.lastname: Park
authors.forename: Hak Chul
authors.initials: HC
authors.lastname: Jang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D044466:Asian People / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology*; D009765:Obesity / Q000208:ethnology*; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D055948:Sarcopenia / Q000208:ethnology*; D017678:Sex Distribution
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