title: A novel bioengineering clinical device testing cellular homeostatic potentials to customize and monitor nutritional-related age-management interventional strategies.
abstract: Most devices assessing body composition harbor a number of drawbacks and hardly assess the phenomena taking place at a cellular membrane level. The present single-frequency bioelectrical potential homeostatic structure analysis (PHoSA) technology requires only a proper hands contact on fixed electrodes and determines the phase displacement between tested current and voltage by using a 50-KHz alternate sinusoidal current. This allows quick testing time with high degree of precision, sensitivity, and specificity of sectorial functional body compartments analysis. Such assessment may prove to be an integrated part of either a diagnostic workup or monitoring tool in tailoring nutritional/nutraceutical, pharmacological, and exercise activity, all being framed within a proactive, preventive, age-intervention management strategy.
authors.affiliation: Rilevo Bioengineering Research Laboratory, Piacenza, Italy. segreteria@Rilevo.com
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Mariani
authors.forename: Franco
authors.initials: F
authors.lastname: Dellaglio
authors.forename: Francesco
authors.initials: F
authors.lastname: Marotta
mesh_terms: D000375:Aging / Q000378:metabolism / Q000502:physiology*; D000886:Anthropometry / Q000295:instrumentation / Q000379:methods; D057005:Bioengineering / Q000295:instrumentation* / Q000379:methods; D001823:Body Composition / Q000502:physiology; D015992:Body Mass Index; D002138:Calibration; D002468:Cell Physiological Phenomena; D004034:Diet Surveys; D004311:Double-Blind Method; D017097:Electric Impedance; D005500:Follow-Up Studies; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D009747:Nutritional Physiological Phenomena; D009752:Nutritional Status; D044968:Regenerative Medicine / Q000295:instrumentation* / Q000379:methods*; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires