title: Endografting in the aortic arch - does the proximal landing zone influence outcome?
abstract: OBJECTIVE
  To analyse early and midterm results of thoracic aortic endografting (TEVAR) in the aortic arch.
  
  
  METHODS
  Between January 1997 and February 2009 178 patients received TEVAR in the aortic arch at our institution. This population was subdivided into four groups according to the proximal landing zone (LZ) classification in the aortic arch by Ishimaru et al. and a retrospective analysis regarding perioperative mortality, morbidity and endoleak formation was performed.
  
  
  RESULTS
  The overall 30-day mortality rate was 14% with no statistical significant difference between LZ's 0-3 (p=0.274). Renal insufficiency (hazard ratio (HR) 2.5; p=0.0119), age >75 years (HR 3.1; p=0.0019) and emergency procedures (HR 8.9; p < 0.0001) were independent predictors of death. There was no significant difference regarding type I (p=0.07) or type III (p=0.49) endoleaks between the proximal LZs, but a significant difference regarding the development of type II endoleaks (p=0.01).
  
  
  CONCLUSIONS
  The present study showed no influence of the proximal LZ on perioperative mortality and morbidity rate. Furthermore it did not influence relevant (type I/III) endoleak formation.
authors.affiliation: Department of Vascular and Endovascular Surgery, Ruprecht - Karls University Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany. philipp.geisbuesch@med.uni-heidelberg.de
authors.forename: P
authors.initials: P
authors.lastname: Geisbüsch
authors.forename: D
authors.initials: D
authors.lastname: Kotelis
authors.forename: A
authors.initials: A
authors.lastname: Hyhlik-Dürr
authors.forename: M
authors.initials: M
authors.lastname: Hakimi
authors.forename: N
authors.initials: N
authors.lastname: Attigah
authors.forename: D
authors.initials: D
authors.lastname: Böckler
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic / Q000601:surgery*; D001015:Aortic Arch Syndromes / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005858:Germany / Q000453:epidemiology; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D015607:Stents; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult