Synthetic and structural studies on amine coordination to Pd-N-heterocyclic carbene complexes.
The reaction between 2-chlorobenzylamine or 2-chlorobenzylalcohol and Pd(I(t)Bu)(2) (I(t)Bu = 1,3-di-tert-butylimidazol-2-ylidene) in benzene affords the dimeric complexes [Pd(I(t)Bu)(mu-NH{2-CH(2)C(6)H(4)})](2) and [Pd(I(t)Bu)(mu-O{2-CH(2)C(6)H(4)})](2); the latter has been structurally characterised. The syntheses, structural characterisation and reactivity of the Pd-NHC amine complexes [(I(t)Bu)Pd(R-4-C(6)H(4))(morpholine)Cl] (R = Me, OMe, CO(2)Me), intermediates in the Buchwald-Hartwig aryl amination reaction, are also reported.
de K Lewis
Alexandra K
AK
Christopher Ingold Laboratories, Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ.
Caddick
Stephen
S
Esposito
Oriana
O
Cloke
F Geoffrey N
FG
Hitchcock
Peter B
PB
D000588:Amines / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006571:Heterocyclic Compounds / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000588:Amines; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C030011:carbene; D010165:Palladium; D008697:Methane