title: [A 37-year-old patient with fever, dyspnea and elevated transaminases after a stay in Mexico].
abstract: METHODS
  A 37-year-old patient with cephalgia and fever after his return from Mexico is reported. Due to persistently elevated transaminases, a liver biopsy was performed. Histological examination revealed hepatic involvement of a granulomatous disease. Serologic analyses detected anti-Brucella IgM. The suspected diagnosis was thus brucellosis taking the typical anamnesis into account. Treatment with rifampicin and doxycycline led to a complete convalescence of the patient.
  
  
  CONCLUSIONS
  Brucellosis is an anthropozoonosis that exists worldwide. Potential sources of infection are uncooked or unpasteurized milk and milk products of infected animals. Complete cure of most brucellosis-infected patients can be achieved by an early and adequate antibiotic treatment.
authors.affiliation: Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg, Regensburg, Germany. Stephan.Schmid@klinik.uni-regensburg.de
authors.forename: Stephan A
authors.initials: SA
authors.lastname: Schmid
authors.forename: Gabriele
authors.initials: G
authors.lastname: Birkenfeld
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood*; D001706:Biopsy; D002002:Brucella / Q000276:immunology; D002006:Brucellosis / Q000175:diagnosis* / Q000473:pathology; D003131:Combined Modality Therapy; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004417:Dyspnea / Q000209:etiology*; D005335:Fever of Unknown Origin / Q000209:etiology*; D006505:Hepatitis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D008800:Mexico; D012293:Rifampin / Q000627:therapeutic use; D014195:Travel; D018084:Ultrasonography, Interventional
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D007075:Immunoglobulin M; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D004318:Doxycycline; D012293:Rifampin
references.citation: Clin Infect Dis. 1995 Aug;21(2):283-9; quiz 290
references.pmid: 8562733
references.citation: Res Vet Sci. 2000 Oct;69(2):135-40
references.pmid: 11020364
references.citation: Antimicrob Agents Chemother. 1995 Sep;39(9):2061-7
references.pmid: 8540716
references.citation: J Lab Clin Med. 1949 Jan;34(1):40-58
references.pmid: 18106408
references.citation: J R Army Med Corps. 1992 Oct;138(3):140-50
references.pmid: 1453384
references.citation: Medicine (Baltimore). 1996 Jul;75(4):195-211
references.pmid: 8699960
references.citation: Rev Infect Dis. 1991 May-Jun;13(3):359-72
references.pmid: 1866536
references.citation: Scand J Infect Dis. 2000;32(1):31-5
references.pmid: 10716074
references.citation: J Bacteriol. 1997 May;179(10):3244-9
references.pmid: 9150220
references.citation: Clin Infect Dis. 1992 Feb;14(2):506-9
references.pmid: 1554839
references.citation: J Clin Microbiol. 2001 Jan;39(1):235-40
references.pmid: 11136777