title: Advance of studies on anti-atherosclerosis mechanism of berberine.
abstract: Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness, purging fire to eliminate toxin. Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis. This paper reviewed the anti-atherosclerosis mechanism of berberine, which may be related to regulating lipids, anti-inflammation, decompression, reducing blood sugar, and inhibiting vascular smooth muscle cell proliferation.
authors.affiliation: Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing (100053), China.
authors.forename: Min
authors.initials: M
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Long-tao
authors.initials: LT
authors.lastname: Liu
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D050197:Atherosclerosis / Q000517:prevention & control*; D001599:Berberine / Q000494:pharmacology* / Q000627:therapeutic use*; D001786:Blood Glucose / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D007249:Inflammation / Q000517:prevention & control; D050356:Lipid Metabolism / Q000187:drug effects; D008055:Lipids / Q000097:blood
chemical_list: D000893:Anti-Inflammatory Agents; D001786:Blood Glucose; D000960:Hypolipidemic Agents; D008055:Lipids; D001599:Berberine
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