title: Epigenetic markers in rectal cancer.
abstract: DNA methylation changes in rectal cancer may serve as a new screening marker and a tool for monitoring recurrence. Importantly, these changes may also function as a predictive marker to allow appropriate exclusion of (neo)adjuvant therapies in patients at low risk for disease recurrence, sparing them from potential treatment-related morbidities.
authors.affiliation: Steele Laboratory, Massachusetts General Hospital, Boston, Massachusetts, USA.
authors.forename: Lei
authors.initials: L
authors.lastname: Xu
authors.forename: Brian G
authors.initials: BG
authors.lastname: Czito
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Willett
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D006801:Humans; D012004:Rectal Neoplasms / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor