title: [Constituents from a water-soluble portion of ethanolic extract of Iodes cirrhosa].
abstract: OBJECTIVE
  To investigate chemical constituents of Iodes cirrhosa.
  
  
  METHODS
  Constituents were isolated by using a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, and C-18, as well as reversed-phase HPLC. Structures of the isolates were identified by spectroscopic and chemical methods.
  
  
  RESULTS
  Twenty-four compounds were obtained from a H2O-soluble portion of an ethanolic extract of the root of lodes cirrhosa Turcz. Structures of the isolates were identified as (-)-(7R,8S,7'E) -4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8,4'-oxyneolign-7'-ene-9'-O-beta-D-glucopyra-noside (1), (-)-(7S,8S,7'E)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8,4'-oxyneolign-7'-ene-9'-O-beta-D-glucopyranoside(2), (+)-(7S,8S)-syringylglycerol 8-O-beta-D-glucopyranoside (3), (+)-(7S, 8S)-guaiacylglycerol 8-O-P-D-glucopyranoside (4), (-)-(7S, 8S)-4,7,9, 9'-tetrahydroxy-3,3'-dimethoxy-8,4'-oxyneolignan-7-O-beta-D-glucopyranoside (5),(-)-alaschanisoside A (6), (-)-(2R)-1-O-beta-D-glucopyranosyl-2-(2-methoxy-4-[1-(E)-propen-3-ol] phenoxyl propane-3-ol(7), (-)-(2R)-1-O-beta-D-glucopyranosyl-2-{2,6-dimethoxy-4-[1-(E)-propen-3-ol] phenoxyl} propane-3-ol(8), (-)-liriodendrin(9), (-)-(7S, 8R)-guaiacylglycerol 9-O-beta-D-glucopyranoside(10), (-)-(7R, 8R)-guaiacylglycerol 9-O-beta-D-glucopyranoside(11),(-)-(7R,8R)-syringylglycerol 9-O-beta-D-glucopyranoside(12), (-)-(7R,8R)-guaiacylglycerol 7-O-beta-D-glucopyranoside(13), (-)-11,13-dihydrodeacylcynaropicrin 3-O-beta-D-glucopyranoside(14), (-)-sweroside (15), (-)-2-hydroxy-5-(2-hydroxyethyl) phenyl beta-D-glucopyranoside(16), (-)-(1'R)-1'-(3-hydroxy-4-methoxyphenyl) ethane-1',2'-diol-3-O-beta-D-glucopyranoside(17), (-)-tachioside(18), (-)-3,5-dimethoxy-4-hydroxyphenyl beta-D-glucopyranoside(19), (-)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone-3-O-beta-D-glucopy ranoside(20), (-)-2-methoxy4-(1-propionyl) phenyl beta-D-glucopyranoside(21), (-)-4-propionyl-3, 5-dimethoxyphenyl beta-D-glucopyranoside(22), erigeside C(23), and scopoletin beta-D-xylopyranosyl-(1-->6)-beta-D-glucopyranoside(24).
  
  
  CONCLUSIONS
  Compounds 1-24 were obtained from the genus for the first time.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Maoluo
authors.initials: M
authors.lastname: Gan
authors.forename: Chenggeni
authors.initials: C
authors.lastname: Zhu
authors.forename: Yanling
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jiachen
authors.initials: J
authors.lastname: Zi
authors.forename: Weixia
authors.initials: W
authors.lastname: Song
authors.forename: Yongchun
authors.initials: Y
authors.lastname: Yang
authors.forename: Jiangong
authors.initials: J
authors.lastname: Shi
mesh_terms: D004365:Drugs, Chinese Herbal / Q000032:analysis*; D000431:Ethanol / Q000737:chemistry; D005960:Glucosides / Q000032:analysis*; D007536:Isomerism; D019684:Magnoliopsida / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D012995:Solubility; D014867:Water / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D005960:Glucosides; D014867:Water; D000431:Ethanol