title: Papuabalanols A and B, new tannins from Balanophora papuana.
abstract: Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hosoya
authors.forename: Asami
authors.initials: A
authors.lastname: Nakata
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Zaima
authors.forename: Jalifah
authors.initials: J
authors.lastname: Latip
authors.forename: Laily Bin
authors.initials: LB
authors.lastname: Din
authors.forename: Noramly
authors.initials: N
authors.lastname: Muslim
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
mesh_terms: D000818:Animals; D031111:Balanophoraceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D013634:Tannins / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D010936:Plant Extracts; D013634:Tannins; D014665:Vasodilator Agents; C551763:papuabalanol A; C551764:papuabalanol B