title: The Schizophrenia Cognition Rating Scale: validation of an interview-based assessment of cognitive functioning in Asian patients with schizophrenia.
abstract: Growing interest in cognitive deficits associated with schizophrenia has led to the need for a clinician-friendly cognitive instrument. The Schizophrenia Cognition Rating Scale (SCoRS), recognized for its brevity and ease of administration, has proven to be a valid and reliable measure of overall cognition in schizophrenia patients. However, there has been no such validation in an Asian context. This SCoRS validation study involved 103 patient and 48 control subjects within an Asian population. Test-retest reliability, sensitivity of the instrument to cognitive differences between patients with schizophrenia and healthy controls as well as validity by comparing with a standardised performance-based cognitive battery, the Brief Assessment of Cognition in Schizophrenia (BACS) were assessed. Our findings indicated that SCoRS is highly reliable (ICC=0.984) and sensitive to cognitive dysfunction. SCoRS is significantly correlated with BACS composite scores and predicted functional outcomes as measured by Global Assessment of Functioning (GAF) and World Health Organisation-Quality of Life (WHO QOL) within an Asian population. SCoRS represents a clinician-friendly cognitive assessment tool that incorporates third-party feedback and might be employed in clinical practice to better evaluate and manage schizophrenia.
authors.affiliation: Research Division, Institute of Mental Health, Singapore, Singapore.
authors.forename: Ming Ying
authors.initials: MY
authors.lastname: Chia
authors.forename: Wai Yen
authors.initials: WY
authors.lastname: Chan
authors.forename: Kok Yeow
authors.initials: KY
authors.lastname: Chua
authors.forename: Helen
authors.initials: H
authors.lastname: Lee
authors.forename: Jimmy
authors.initials: J
authors.lastname: Lee
authors.forename: Rebecca
authors.initials: R
authors.lastname: Lee
authors.forename: Caroline
authors.initials: C
authors.lastname: Lim
authors.forename: Eugene
authors.initials: E
authors.lastname: Tay
authors.forename: Puay San
authors.initials: PS
authors.lastname: Woon
authors.forename: Richard S E
authors.initials: RS
authors.lastname: Keefe
authors.forename: Kang
authors.initials: K
authors.lastname: Sim
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology; D055815:Young Adult