title: [Investigation of simplified international diagnostic criteria for autoimmune hepatitis].
abstract: The simplified international diagnostic criteria for autoimmune hepatitis (AIH), re-revised by the International AIH Group in 2008, were investigated in 114 patients with AIH from 15 centers in Japan. While applying of the criteria, we had to pay attention to anti-nuclear antibody measurement methods, and liver histology scoring. Definite and probable AIH were diagnosed in 83 and 22 patients, respectively. The criteria were found to be useful for the diagnosis of AIH in Japan. However, 9 patients who did not meet the diagnostic criteria showed normal immunoglobulin G levels or were negative for autoantibodies. As the criteria were unreliable for diagnosing such atypical cases in the present series, we speculated that we should not rely solely on these, criteria and take a more holistic approach to diagnosis in such cases.
authors.affiliation: Department of Gastroenterology, NTT West Osaka Hospital, Japan. a.kaneko@mhc.west.ntt.co.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Kaneko
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Kubo
authors.forename: Ryoko
authors.initials: R
authors.lastname: Yamada
authors.forename: Tomoki
authors.initials: T
authors.lastname: Tanimura
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yamaguchi
authors.forename: Moritoshi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Tatsumi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Nakama
authors.forename: Eiji
authors.initials: E
authors.lastname: Mita
authors.forename: Michio
authors.initials: M
authors.lastname: Kato
authors.forename: Taizo
authors.initials: T
authors.lastname: Hijioka
authors.forename: Masahide
authors.initials: M
authors.lastname: Oshita
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Ito
authors.forename: Kazuho
authors.initials: K
authors.lastname: Imanaka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katayama
authors.forename: Masako
authors.initials: M
authors.lastname: Sato
authors.forename: Harumasa
authors.initials: H
authors.lastname: Yoshihara
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kiriyama
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Imai
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kashihara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fukui
authors.forename: Kunio
authors.initials: K
authors.lastname: Suzuki
authors.forename: Shio
authors.initials: S
authors.lastname: Miyoshi
authors.forename: Akira
authors.initials: A
authors.lastname: Yamada
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yakushijin
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Naoki
authors.initials: N
authors.lastname: Hiramatsu
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Takehara
authors.forename: Norio
authors.initials: N
authors.lastname: Hayashi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D019693:Hepatitis, Autoimmune / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged