title: First whole genome characterization of swine influenza virus subtype H3N2 in Thailand.
abstract: H3N2 swine influenza viruses (SIV) were first detected in Asia shortly after the 1968 pandemic emerged in humans. Subsequently, human H3N2 viruses have sporadically reappeared in swine. In Thailand, a human-like H3N2 SIV was reported in 1978 although the genetic sequence of this virus is unknown. In this study, we undertook cross sectional syndromic surveillance in pigs in four provinces in Thailand. Seven genetically similar H3N2 viruses were isolated. A representative, A/SW/Thailand/KU5.1/04, was fully sequenced and shown to contain genes from human-like influenza viruses and North American and European SIV. The results restate that transmission of influenza A virus among human and swine populations is common and that genes from both American and Eurasian SIV lineages cocirculate in Thailand.
authors.affiliation: Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, 50 Paholyothin Road, Bangkok, Thailand. fvetptn@ku.ac.th
authors.forename: Porntippa
authors.initials: P
authors.lastname: Lekcharoensuk
authors.forename: Jinpanee
authors.initials: J
authors.lastname: Nanakorn
authors.forename: Worawidh
authors.initials: W
authors.lastname: Wajjwalku
authors.forename: Richard
authors.initials: R
authors.lastname: Webby
authors.forename: Wilairat
authors.initials: W
authors.lastname: Chumsing
mesh_terms: D000818:Animals; D001483:Base Sequence; D003430:Cross-Sectional Studies; D016679:Genome, Viral; D053122:Influenza A Virus, H3N2 Subtype / Q000235:genetics*; D008969:Molecular Sequence Data; D009976:Orthomyxoviridae Infections / Q000235:genetics / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D017422:Sequence Analysis, DNA; D013552:Swine; D013553:Swine Diseases / Q000235:genetics / Q000821:virology*; D013785:Thailand
chemical_list: D012367:RNA, Viral