[Digestive tract, obesity and cancer].
Current statistics show that overweight and obesity are seriously increasing, mainly in occidental countries with high industrialization rate. Simultaneously sedentarism has increased as a consequence of technological comforts that the dominant market economy offers. Obesity, sedentarism, excessive adiposity, especially if centrally distributed, insulin resistance and hyperinsulinemia interact for cancer development. Visceral adipose tissue is considerate as an endocrine organ which produces and liberates cytokines and inflammatory peptides with hormonal and metabolic signals. Although there are several obesity-related types of cancer, in this paper we focus on digestive system tumors.
Actis
Andrea
A
Departamento de Bioquímica Humana, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Outomuro
Delia
D
D004067:Digestive System Neoplasms / Q000209:etiology*; D006801:Humans; D009765:Obesity / Q000150:complications*