title: Serum proteinogram of cats experimentally infected by Trypanosoma evansi.
abstract: This study was aimed at evaluating the electrophoretic profile of serum proteins in Trypanosoma evansi-infected cats during different periods of infection. Thirteen adult females non-breeding Felis catus were separated into two groups. Animals from the infected group (n=7) were inoculated intraperitoneally with a strain of T. evansi; whereas, animals from the control group (n=6) received a physiological solution. Blood samples were collected at days 0, 7, 21, and 35 for total protein evaluation and protein fractionation by electrophoresis. Albumin (P<0.01), alpha-2 globulin and gamma globulin (P<0.05) concentrations were statistically different from the seventh day post-inoculation onwards. Beta-globulin levels were increased from day 21 onwards (P<0.05). Alpha-1 globulin fraction did not differ statistically. These results indicate that the infection by T. evansi in cats alters the serum protein electrophoretic profile.
authors.affiliation: Small Animals Department, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil. marmcvet@yahoo.com.br
authors.forename: Márcio Machado
authors.initials: MM
authors.lastname: Costa
authors.forename: Aleksandro Schafer
authors.initials: AS
authors.lastname: da Silva
authors.forename: Patrícia
authors.initials: P
authors.lastname: Wolkmer
authors.forename: Régis Adriel
authors.initials: RA
authors.lastname: Zanette
authors.forename: Raqueli Teresinha
authors.initials: RT
authors.lastname: França
authors.forename: Silvia Gonzalez
authors.initials: SG
authors.lastname: Monteiro
authors.forename: Sonia Terezinha
authors.initials: ST
authors.lastname: dos Anjos Lopes
mesh_terms: D000818:Animals; D001797:Blood Protein Electrophoresis / Q000662:veterinary; D001798:Blood Proteins / Q000032:analysis*; D002371:Cat Diseases / Q000097:blood* / Q000469:parasitology; D002415:Cats; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D012712:Serum Globulins / Q000032:analysis; D014352:Trypanosomiasis / Q000097:blood / Q000662:veterinary*
chemical_list: D001798:Blood Proteins; D006454:Hemoglobins; D012712:Serum Globulins