dsDNA-triggered energy transfer and lanthanide sensitization processes. Luminescent probing of specific A/T sequences.
Orthogonal attachment of a DOTA[Ln(3+)] complex or a coumarin fluorophore to appropriately functionalized bis-4-aminobenzamidines yields compounds that experience A/T-selective, dsDNA-dependent energy transfer processes, and elicit long wavelength emission of light.
Vázquez
Olalla
O
Dept. de Química Orgánica, Facultade de Química, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Sánchez
Mateo I
MI
Mascareñas
José L
JL
Vázquez
M Eugenio
ME
D020856:AT Rich Sequence; D001483:Base Sequence; D001550:Benzamidines / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D004735:Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry*; D006573:Heterocyclic Compounds, 1-Ring / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D049449:Luminescence
D001550:Benzamidines; D003374:Coumarins; D005456:Fluorescent Dyes; D006573:Heterocyclic Compounds, 1-Ring; D028581:Lanthanoid Series Elements; C071349:1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid; C006500:4-aminobenzamidine; D004247:DNA; C030123:coumarin