title: Hyperperfusion syndrome after clipping an unruptured cerebral aneurysm: two case reports.
abstract: A 68-year-old woman presented with severe headache 9 days after undergoing successful clipping of a right middle cerebral artery aneurysm. Postoperative imaging revealed increased perfusion and diffuse edema in the right frontotemporal cortex. A 57-year-old woman exhibited perseveration soon after undergoing successful clipping of an anterior communicating artery aneurysm. Postoperative imaging studies revealed increased perfusion and diffuse edema in the left frontal and insular cortex. The symptoms and diffuse edema gradually resolved in both patients. These two cases of hyperperfusion syndrome occurred in a series of 190 patients treated by clipping of unruptured cerebral aneurysms. Hyperperfusion syndrome is a rare complication following aneurysm surgery, especially surgery for unruptured cerebral aneurysms without temporary clipping.
authors.affiliation: Department of Neurosurgery, Obihiro Kosei General Hospital, Obihiro, Hokkaido, Japan. t-sugino@sapmed.ac.jp
authors.forename: Toshiya
authors.initials: T
authors.lastname: Sugino
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ohtaki
authors.forename: Masahiko
authors.initials: M
authors.lastname: Wanibuchi
authors.forename: Sonen
authors.initials: S
authors.lastname: Kin
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Houkin
mesh_terms: D000368:Aged; D002540:Cerebral Cortex / Q000098:blood supply* / Q000473:pathology; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000473:pathology; D004487:Edema / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D002532:Intracranial Aneurysm / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology; D013525:Surgical Instruments; D013577:Syndrome; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects* / Q000295:instrumentation