title: Measurement of splanchnic photoplethysmographic signals using a new reflectance fiber optic sensor.
abstract: Splanchnic organs are particularly vulnerable to hypoperfusion. Currently, there is no technique that allows for the continuous estimation of splanchnic blood oxygen saturation (SpO(2)). As a preliminary to developing a suitable splanchnic SpO(2) sensor, a new reflectance fiber optic photoplethysmographic (PPG) sensor and processing system are developed. An experimental procedure to examine the effect of fiber source detector separation distance on acquired PPG signals is carried out before finalizing the sensor design. PPG signals are acquired from four volunteers for separation distances of 1 to 8 mm. The separation range of 3 to 6 mm provides the best quality PPG signals with large amplitudes and the highest signal-to-noise ratios (SNRs). Preliminary calculation of SpO(2) shows that distances of 3 and 4 mm provide the most realistic values. Therefore, it is suggested that the separation distance in the design of a fiber optic reflectance pulse oximeter be in the range of 3 to 4 mm. Preliminary PPG signals from various splanchnic organs and the periphery are obtained from six anaesthetized patients. The normalized amplitudes of the splanchnic PPGs are, on average, approximately the same as those obtained simultaneously from the periphery. These observations suggest that fiber optic pulse oximetry may be a valid monitoring technique for splanchnic organs.
authors.affiliation: City University London, School of Engineering and Mathematical Sciences, Northampton Square, London, EC1V 0HB United Kingdom. m.hickey@city.ac.uk
authors.forename: Michelle
authors.initials: M
authors.lastname: Hickey
authors.forename: Neal
authors.initials: N
authors.lastname: Samuels
authors.forename: Nilesh
authors.initials: N
authors.lastname: Randive
authors.forename: Richard M
authors.initials: RM
authors.lastname: Langford
authors.forename: Panayiotis A
authors.initials: PA
authors.lastname: Kyriacou
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006801:Humans; D010092:Oximetry / Q000295:instrumentation*; D017156:Photoplethysmography / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013152:Splanchnic Circulation / Q000502:physiology*; D014159:Transducers