title: Curvularia keratomycosis in a dog.
abstract: A 10-year-old, spayed female Bichon Frise was referred to the Veterinary Medical Center of the University of Florida with a 6-week history of blepharospasm and a nonhealing ulcer of the left eye. Ophthalmic examination revealed a 3-4 mm diameter corneal ulcer with faint edema at the lesion edge, and a raised grayish area on the paraxial cornea near the 2 o'clock position. Cytological testing revealed fungal hyphae and extracellular cocci. Culture of the lesion found heavy growth of Enterococcus faecalis and Curvularia spp. Treatment with a combination of topical antibiotics (polymyxin B, sulfate/trimetoprim, and 10% sulfacetamide sodium), 1% miconazole, autologous serum, and 5% hypertonic saline was instituted. After 8 days of medical therapy, an improvement of clinical signs was noted, and 15 days after initiation of treatment, the ulcer was healed with minimal corneal scarring.
authors.affiliation: Department of Small and Large Animal Clinical Sciences, Ophthalmology Service, University of Florida, Gainesville, FL, USA. gil.benshlomo@yahoo.com
authors.forename: Gil
authors.initials: G
authors.lastname: Ben-Shlomo
authors.forename: Caryn
authors.initials: C
authors.lastname: Plummer
authors.forename: Kathleen
authors.initials: K
authors.lastname: Barrie
authors.forename: Dennis
authors.initials: D
authors.lastname: Brooks
mesh_terms: D000818:Animals; D001203:Ascomycota / Q000145:classification / Q000302:isolation & purification*; D004283:Dog Diseases / Q000382:microbiology* / Q000473:pathology; D004285:Dogs; D015821:Eye Infections, Fungal / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D007634:Keratitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*