title: Canadian global village reality: anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent.
abstract: OBJECTIVE
  To test the appropriateness of body mass index (BMI) and waist circumference (WC) cutoff points derived in largely white populations (ie, those of European descent) for detecting obesity-related metabolic abnormalities among East Asian and South Asian Canadians.
  
  
  METHODS
  Cross-sectional survey.
  
  
  METHODS
  Primary care and community settings in Ontario.
  
  
  METHODS
  Canadians of East Asian (n = 130), South Asian (n = 113), and European (n = 111) descent.
  
  
  METHODS
  Variables for metabolic syndromes, including BMI, WC, body fat percentage, blood pressure, lipid profile, and fasting blood glucose and insulin levels, were measured. Receiver operating characteristics curve analysis was used to generate BMI and WC cutoff points based on various criteria for metabolic syndromes.
  
  
  RESULTS
  Adjusting for sex and age, East Asian Canadians had a significantly lower mean BMI (23.2 kg/m(2)) and mean WC (79.6 cm) than did those of South Asian (26.1 kg/m(2) and 90.3 cm) and European (26.5 kg/m(2) and 89.3 cm) descent (P < .05). The BMI cutoffs for an increased risk of metabolic abnormalities ranged from 23.1 to 24.4 kg/m(2) in East Asian Canadians; 26.6 to 26.8 kg/m(2) in South Asian Canadians; and 26.3 to 28.2 kg/m(2) in European Canadians. Waist circumference cutoffs for increased risk of metabolic abnormalities were relatively low in East Asian men (83.3 to 85.2 cm) and women (74.1 to 76.7 cm), compared with South Asian men (98.8 cm) and women (90.1 to 93.5 cm), as well as European men (91.6 to 95.2 cm) and women (82.8 to 88.3 cm).
  
  
  CONCLUSIONS
  The BMI and WC cutoffs used for defining risk of metabolic abnormalities should be lowered for East Asian Canadians but not for South Asian Canadians. The World Health Organization ethnic-specific BMI and WC cutoffs should be used with caution, particularly with Asian migrants who have resided in Canada for a long period of time.
authors.affiliation: University of Texas at San Antonio, Department of Health and Kinesiology, One UTSA Circle, San Antonio, TX 78249, USA. meizi.he@utsa.edu
authors.forename: Meizi
authors.initials: M
authors.lastname: He
authors.forename: E T S
authors.initials: ET
authors.lastname: Li
authors.forename: Stewart
authors.initials: S
authors.lastname: Harris
authors.forename: Murray W
authors.initials: MW
authors.lastname: Huff
authors.forename: Chun Y
authors.initials: CY
authors.lastname: Yau
authors.forename: G Harvey
authors.initials: GH
authors.lastname: Anderson
mesh_terms: D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D002170:Canada; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005202:Asia, Eastern / Q000208:ethnology; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D008297:Male; D008659:Metabolic Diseases / Q000208:ethnology*; D008875:Middle Aged; D012372:ROC Curve; D012016:Reference Values; D012737:Sex Factors; D055105:Waist Circumference; D044465:White People
references.citation: Biomed Environ Sci. 2002 Mar;15(1):83-96
references.pmid: 12046553
references.citation: Int J Obes (Lond). 2005 Jun;29(6):656-67
references.pmid: 15782225
references.citation: Asia Pac J Clin Nutr. 2005;14(1):74-9
references.pmid: 15734711
references.citation: Int J Obes (Lond). 2005 Feb;29(2):228-35
references.pmid: 15570315
references.citation: Int J Obes Relat Metab Disord. 2001 May;25(5):748-52
references.pmid: 11360160
references.citation: Clin Chem. 1993 Apr;39(4):561-77
references.pmid: 8472349
references.citation: Diabetes Care. 2003 May;26(5):1380-4
references.pmid: 12716792
references.citation: Stat Med. 1997 Jul 15;16(13):1529-42
references.pmid: 9249923
references.citation: Int J Obes Relat Metab Disord. 2002 Sep;26(9):1232-8
references.pmid: 12187401
references.citation: CMAJ. 2004 Nov 23;171(11):1361-3
references.pmid: 15557589
references.citation: Diabet Med. 1998 Jul;15(7):539-53
references.pmid: 9686693
references.citation: Circulation. 2005 Oct 25;112(17):2735-52
references.pmid: 16157765
references.citation: Int J Obes Relat Metab Disord. 1998 Dec;22(12):1164-71
references.pmid: 9877251
references.citation: Diabetes Care. 2000 Jan;23(1):57-63
references.pmid: 10857969
references.citation: Lancet. 2004 Jan 10;363(9403):157-63
references.pmid: 14726171
references.citation: Lancet. 2005 Sep 24-30;366(9491):1059-62
references.pmid: 16182882
references.citation: J Am Coll Cardiol. 2007 May 29;49(21):2112-9
references.pmid: 17531661
references.citation: Diabetes Res Clin Pract. 2005 Oct;70(1):63-70
references.pmid: 16126124
references.citation: Am J Clin Nutr. 1994 Jul;60(1):23-8
references.pmid: 8017333
references.citation: Circulation. 2007 Apr 24;115(16):2111-8
references.pmid: 17420343
references.citation: Br J Nutr. 1974 Jul;32(1):77-97
references.pmid: 4843734
references.citation: Atherosclerosis. 2006 Jun;186(2):367-73
references.pmid: 16112123
references.citation: Clin Dermatol. 2004 Jul-Aug;22(4):276-80
references.pmid: 15475226
references.citation: World Health Organ Tech Rep Ser. 2000;894:i-xii, 1-253
references.pmid: 11234459
references.citation: Diabetologia. 1985 Jul;28(7):412-9
references.pmid: 3899825