title: [Use abusive of benzydamine in Brazil: an overview in pharmacovigilance].
abstract: The abusive drug use has been object of increasing concern in public health and is commonly issued in the Brazilian press. Amongst medicines, those that are abuse substances and cause physical and/or psychic dependence, barbiturates, benzodiazepines, opioid analgesics and amphetamines are included. Analgesics, antipyretics and non-steroidal anti-inflammatory drugs, even not making part of this list, are generally associated with recreational use or non therapeutical purpose. The objective of this essay is to present information on the abusive use of benzydamine in Brazil. The present study is an exploratory essay in which different methodological strategies adopted in the regulatory practice of pharmacovigilance have been used. The abusive use of this drug was evidenced in scientific literature, press releases and on the internet. Considering the facility of purchasing drugs under medical prescription, among other factors, it must be demanded ways to assess the marketing and use of medicines, and assure its safe and rational use, including the strengthening of pharmacovigilance in Brazil.
authors.affiliation: Agência Nacional de Vigilância Sanitária, Brasília, DF, 71205-050. daniel.mota@anvisa.gov.br
authors.forename: Daniel Marques
authors.initials: DM
authors.lastname: Mota
authors.forename: Alessandra Alves da
authors.initials: AA
authors.lastname: Costa
authors.forename: Christiane Dos Santos
authors.initials: Cdos S
authors.lastname: Teixeira
authors.forename: Augusto Amorim
authors.initials: AA
authors.lastname: Bastos
authors.forename: Murilo Freitas
authors.initials: MF
authors.lastname: Dias
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D001591:Benzydamine / Q000009:adverse effects* / Q000494:pharmacology; D001938:Brazil; D006801:Humans; D019966:Substance-Related Disorders / Q000453:epidemiology*
chemical_list: D001591:Benzydamine