title: Learning from the pregnane X receptor: how to fight one aggressor with two strategies.
authors.forename: Christian
authors.initials: C
authors.lastname: Rust
authors.forename: Ulrich
authors.initials: U
authors.lastname: Beuers
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002756:Cholagogues and Choleretics / Q000494:pharmacology; D015209:Cholangitis, Sclerosing / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D002780:Cholestasis, Intrahepatic / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D004195:Disease Models, Animal; D005999:Glycochenodeoxycholic Acid / Q000494:pharmacology; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D000077297:Pregnane X Receptor; D051381:Rats; D011987:Receptors, Steroid / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014580:Ursodeoxycholic Acid / Q000494:pharmacology
chemical_list: D002756:Cholagogues and Choleretics; D000077297:Pregnane X Receptor; D011987:Receptors, Steroid; D005999:Glycochenodeoxycholic Acid; D014580:Ursodeoxycholic Acid