title: Relations between respiratory changes in R-wave amplitude and arterial pulse pressure in mechanically ventilated patients.
abstract: BACKGROUND
  R-wave obtained from the electrocardiogram depends on ventricular stroke volume. We assessed the relationship between respiratory variations in R-wave (DeltaRDII) and in pulse pressure (DeltaPP) during general anesthesia.
  
  
  METHODS
  R-wave amplitude was measured from standard lead II (RDII). Maximal RDII (RDIImax) and minimal RDII (RDIImin) were determined over one respiratory cycle. DeltaRDII was calculated as 100 x [RDIImax-RDIImin]/([RDIImax + RDIImin]/2. DeltaRDII and DeltaPP were simultaneously recorded.
  
  
  RESULTS
  There was a significant relationship (r = 0.79; P < 0.001) between DeltaRDII and DeltaPP. A DeltaRDII > 13% detected patients with a DeltaPP > 13% with an 89% sensitivity, and an 88% specificity.
  
  
  CONCLUSIONS
  DeltaRDII and DeltaPP are related in this setting.
authors.affiliation: Department of Anesthesiology & Perioperative Care, University of California, Irvine, Orange, 92868-3301, USA. maxime_cannesson@hotmail.com
authors.forename: Maxime
authors.initials: M
authors.lastname: Cannesson
authors.forename: Geoffray
authors.initials: G
authors.lastname: Keller
authors.forename: Olivier
authors.initials: O
authors.lastname: Desebbe
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Lehot
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001794:Blood Pressure / Q000502:physiology*; D002245:Carbon Dioxide / Q000032:analysis; D004562:Electrocardiography; D045853:Exhalation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D012119:Respiration; D012121:Respiration, Artificial; D013318:Stroke Volume
chemical_list: D002245:Carbon Dioxide
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