title: Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus.
abstract: In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at the highest concentration (3 mg/mL) at all time points.
authors.affiliation: Department of Physics, Brown University, Providence, Rhode Island, USA.
authors.forename: Nhiem
authors.initials: N
authors.lastname: Tran
authors.forename: Aparna
authors.initials: A
authors.lastname: Mir
authors.forename: Dhriti
authors.initials: D
authors.lastname: Mallik
authors.forename: Arvind
authors.initials: A
authors.lastname: Sinha
authors.forename: Suprabha
authors.initials: S
authors.lastname: Nayar
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Webster
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005290:Ferric Compounds / Q000008:administration & dosage*; D008422:Materials Testing; D053758:Nanoparticles / Q000008:administration & dosage*; D010316:Particle Size; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; C000499:ferric oxide
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