[Distal pancreatectomy with splenectomy and en bloc resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk].
BACKGROUND
Locally advanced cancer of the body of the pancreas with infiltration of the celiac trunk and its branches is often considered an unresectable disease. Distal pancreatectomy with resection of the celiac trunk was described as a new concept for the curative treatment of these tumors.


METHODS
The case of a 61-year-old female patient is reported, who underwent distal pancreatectomy with splenectomy and resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk. The celiac trunk was embolized preoperatively in order to assure arterial perfusion of the liver.


CONCLUSIONS
Distal pancreatectomy with en bloc resection of the celiac trunk offers a high resectability rate and thus a curative option for locally advanced cancer of the pancreatic body with vascular invasion. The optimization of patient selection and the development of effective adjuvant chemotherapy could significantly improve the survival of patients subjected to this operation.
Andreou
Andreas
A
Klinik für Allgemein-, Visceral- und Transplantationschirurgie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany. andreas.andreou@charite.de
Glanemann
Matthias
M
Guckelberger
Olaf
O
Denecke
Timm
T
Grieser
Christian
C
Podrabsky
Petr
P
Neuhaus
Peter
P
D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000601:surgery*; D002445:Celiac Artery / Q000473:pathology* / Q000601:surgery*; D049448:Cholangiopancreatography, Magnetic Resonance; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007511:Ischemia / Q000517:prevention & control; D008099:Liver / Q000098:blood supply; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy / Q000379:methods*; D010183:Pancreatic Ducts / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D011300:Preoperative Care; D011379:Prognosis; D013154:Spleen / Q000473:pathology; D013156:Splenectomy / Q000379:methods*; D013270:Stomach / Q000098:blood supply; D014057:Tomography, X-Ray Computed
Am J Surg. 1992 Jul;164(1):26-31
1378243
J Gastrointest Surg. 2002 Mar-Apr;6(2):147-57; discussion 157-8
11992799
JOP. 2001 May;2(3):93-7
11870330
Ann Surg. 2007 Jul;246(1):46-51
17592290
Br J Surg. 1996 Aug;83(8):1065-70
8869304
Hepatogastroenterology. 1997 Mar-Apr;44(14):387-93
9164507
Dig Surg. 1999;16(4):305-12
10449975
Hepatogastroenterology. 2000 Sep-Oct;47(35):1447-9
11100373
Br J Surg. 1993 Sep;80(9):1177-9
8402126
Pancreas. 2004 Apr;28(3):219-30
15084961
J Gastrointest Surg. 2000 Nov-Dec;4(6):567-79
11307091
J Surg Oncol. 1997 Jul;65(3):164-70
9236924
J Gastrointest Surg. 2005 Apr;9(4):503-7
15797231
Hepatobiliary Pancreat Dis Int. 2003 Nov;2(4):622-5
14627533
Int J Pancreatol. 1997 Aug;22(1):15-21
9387020
J Clin Oncol. 1999 Aug;17(8):2419-28
10561305
J Hepatobiliary Pancreat Surg. 2009;16(2):229-33
19224117
Am J Surg. 2006 Sep;192(3):330-5
16920427
Langenbecks Arch Surg. 2003 Apr;388(2):101-6
12684805
J Hepatobiliary Pancreat Surg. 2001;8(5):441-8
11702254
J Hepatobiliary Pancreat Surg. 2005;12(1):55-60
15754101
J Gastrointest Surg. 2007 Jun;11(6):743-9
17417712
Eur J Surg Oncol. 2009 Oct;35(10):1124-7
19410414