Glycosyl-nucleoside-lipid based supramolecular assembly as a nanostructured material with nucleic acid delivery capabilities.
A glycosyl-nucleoside-lipid self-assembles to give highly organized structures such as fibers and nanotubes, which can stabilize hydrogels; carbohydrate moieties provide a suitable environment to deliver nucleic acids into human cells.
Godeau
Guilhem
G
INSERM U869, Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.
Bernard
Julie
J
Staedel
Cathy
C
Barthélémy
Philippe
P
D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems; D005947:Glucose / Q000737:chemistry*; D022781:Hepatocytes / Q000737:chemistry; D006801:Humans; D020100:Hydrogels / Q000737:chemistry; D008055:Lipids / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties; D014162:Transfection
D004337:Drug Carriers; D020100:Hydrogels; D008055:Lipids; D046911:Macromolecular Substances; D009841:Oligonucleotides; D005947:Glucose