[Roles of dendritic cell in disease progression of AIDS primate models].
Non-human primate models are widely used in research of AIDS mechanism, transmission, vaccine and drugs. Dendritic cells (DC), as antigen presenting cells linking the innate immunity and acquired immunity, play a pivotal role in AIDS progression. Studies on the change of DC subsets number, phenotype and function in AIDS non-human primate models are important for revealing some mechanism of AIDS progression. This article reviews the progress in DC subsets of non-human primate AIDS models, which will provide an avenue for further study in AIDS.
Xia
Hou-Jun
HJ
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.
Zhang
Gao-Hong
GH
Zheng
Yong-Tang
YT
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000473:pathology* / Q000821:virology; D000818:Animals; D003713:Dendritic Cells / Q000276:immunology* / Q000821:virology; D004195:Disease Models, Animal; D018450:Disease Progression; D006801:Humans; D011323:Primates