title: Comparison between clinical and ultrasonographic findings in cases of periportal fibrosis in an endemic area for schistosomiasis mansoni in Brazil.
abstract: BACKGROUND
  Abdominal palpation and ultrasound findings among patients from an endemic area for schistosomiasis in Brazil who had been followed up for 27 years were compared.
  
  
  METHODS
  In 2004, 411 patients from Brejo do Espírito Santo, in the State of Bahia, were selected for the present investigation after giving their written informed consent. Based on clinical data, they were divided into three groups: 41 patients with evidence of liver fibrosis in 2004 (Group 1); 102 patients with evidence of liver fibrosis in the past (1976-1989) but not in 2004 (Group 2); and 268 patients without evidence of liver fibrosis at any time during the 27-year follow-up (Group 3). All of the patients underwent abdominal ultrasound in which the examiner did not know the result from the clinical examination. The data were stored in a database.
  
  
  RESULTS
  The prevalence of periportal fibrosis on ultrasound was 82.9%, 56.9% and 13.4% in Groups 1, 2 and 3, respectively. In the presence of hard, nodular liver or prominent left lobe and a hard palpable spleen, ultrasound revealed periportal fibrosis in 70.9%. However, periportal fibrosis was diagnosed using ultrasound in 25.4% of the patients in the absence of clinical evidence of liver involvement. Thus, ultrasound diagnosed periportal fibrosis 3.1 times more frequently than clinical examination did.
  
  
  CONCLUSIONS
  Although clinical examination is important in evaluating morbidity due to Manson's schistosomiasis in endemic areas, ultrasound is more accurate in diagnosing liver involvement and periportal fibrosis.
authors.affiliation: University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
authors.forename: Aluízio
authors.initials: A
authors.lastname: Prata
authors.forename: Raiza
authors.initials: R
authors.lastname: Ruiz-Guevara
authors.forename: Carlos Mauricio de Figueiredo
authors.initials: CM
authors.lastname: Antunes
authors.forename: Carolina Coimbra
authors.initials: CC
authors.lastname: Marinho
authors.forename: Leonardo Campos
authors.initials: LC
authors.lastname: Queiroz
authors.forename: Izabela
authors.initials: I
authors.lastname: Voieta
authors.forename: José Roberto
authors.initials: JR
authors.lastname: Lambertucci
mesh_terms: D000328:Adult; D001938:Brazil; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D010173:Palpation; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000469:parasitology* / Q000473:pathology; D012555:Schistosomiasis mansoni / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000469:parasitology; D014463:Ultrasonography