title: Hearing organ disorders in patients with systemic sclerosis.
abstract: In systemic sclerosis (SSc), there may develop hearing and balance disorders as a result of the immune-mediated vasculitis and fibrosis in the inner ear. The objective of the study was evaluation of the hearing organ function in patients with SSc with relationship to duration of the disease and Raynaud phenomenon and also to type and severity of the disease. Twenty unselected, consecutive patients with SSc diagnosed in compliance with the international diagnostic criteria of the American Rheumatism Association (1982), were enrolled into the study. The control group consisted of 26 otologically healthy persons matched to the SSc group for age and sex. Case history was recorded for all patients from questionnaire data. Otolaryngological examination and battery of audiological tests (pure tone audiometry, speech audiometry, impedance audiometry and auditory brainstem response-ABR) were performed. In the anamnesis 60% of patients reported vertigo, 55% headaches, 50% tinnitus, 40% hyperacusis, 40% hearing loss and 30% ear fullness. It was found that patients with SSc had significantly poorer mean hearing thresholds than the control group for 0.5, 1, 6 and 8 kHz. In ABR there were no differences between SSc and control groups although an increase of latency averages in the group of limited patients with SSc compared with the diffuse patients with SSc was observed. In eight patients (40%) sensorineural hearing loss, mostly bilateral and symmetrical was found. Furthermore, no relation was seen between hearing level and duration, type and severity of the disease. Ear involvement is frequent in systemic sclerosis and should be taken into consideration during diagnostic and therapeutic procedures.
authors.affiliation: Department of Otolaryngology, Medical University of Lodz, 22, Kopcinskiego St., 90-153 Lodz, Poland. k.maciaszczyk@op.pl
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Maciaszczyk
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Waszczykowska
authors.forename: Anna
authors.initials: A
authors.lastname: Pajor
authors.forename: Bożena
authors.initials: B
authors.lastname: Bartkowiak-Dziankowska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Durko
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D006320:Hearing Tests / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D012737:Sex Factors; D012867:Skin / Q000473:pathology
references.citation: Medicine (Baltimore). 2008 May;87(3):131-141
references.pmid: 18520322
references.citation: J Laryngol Otol. 1987 Jul;101(7):656-62
references.pmid: 3625016
references.citation: Tenn Med. 2004 Mar;97(3):117-9
references.pmid: 15054944
references.citation: ORL J Otorhinolaryngol Relat Spec. 1994 Jul-Aug;56(4):195-8
references.pmid: 8078672
references.citation: J Laryngol Otol. 2005 Jul;119(7):529-33
references.pmid: 16175977
references.citation: Arthritis Rheum. 1980 May;23(5):581-90
references.pmid: 7378088
references.citation: J Laryngol Otol. 2003 Mar;117(3):212-4
references.pmid: 12648380
references.citation: Eur Arch Otorhinolaryngol. 2006 Sep;263(9):809-15
references.pmid: 16763823
references.citation: Otolaryngol Pol. 1979;33(1):95-104
references.pmid: 440764
references.citation: Otolaryngol Head Neck Surg. 2001 May;124(5):522-5
references.pmid: 11337656
references.citation: Curr Opin Otolaryngol Head Neck Surg. 2004 Oct;12(5):426-30
references.pmid: 15377956
references.citation: Ann Intern Med. 1997 Mar 15;126(6):450-3
references.pmid: 9072930
references.citation: Otolaryngol Head Neck Surg. 2007 Jan;136(1):82-6
references.pmid: 17210339
references.citation: Ann Rheum Dis. 2001 Jun;60(6):592-8
references.pmid: 11350848
references.citation: Haematologica. 2006 Dec;91(12 Suppl):ECR46
references.pmid: 17194652
references.citation: Arthritis Rheum. 2000 Nov;43(11):2437-44
references.pmid: 11083266
references.citation: J Laryngol Otol. 2005 Jul;119(7):534-9
references.pmid: 16175978
references.citation: J Laryngol Otol. 1995 Aug;109(8):713-8
references.pmid: 7561491
references.citation: Arthritis Rheum. 1979 Feb;22(2):130-40
references.pmid: 420706
references.citation: Medicine (Baltimore). 1980 Mar;59(2):149-59
references.pmid: 6244477
references.citation: Dermatologica. 1984;168(4):206
references.pmid: 6724075