[Detection of antibodies to A/H5N1 influenza virus in citizens of Russian Federation].
OBJECTIVE
To determine levels of antibodies to influenza virus A/H5N1 in serum samples of people living in different regions of Russia in order to assess the risk of infection with avian influenza H5N1.


METHODS
Two thousand one hundred sixty-eight serum samples were tested by hemagglutination inhibition assay for the presence of antibodies to influenza virus A/H5N1.


RESULTS
Twenty-six serum samples obtained from residents of Khanty-Mansiysk Autonomous Area and 2 samples from residents of Novosibirsk region were positive for antibodies to serotype A/H5. There were no clinical cases of avain influenza A/H5N1 infection in medical history of studied persons.


CONCLUSIONS
Since cases of asymptomatic carriage of A/H5N1 influenza virus in water birds are described and ability of the virus to survive in water environment for a long time is shown, it seems logical to detect antibodies to influenza virus A/H5 in sera of subjects living in Russian Federation taking into account that influenza virus A/H5N1 is isolated from wild fowl and poultry since 2005.
Onishchenko
G G
GG
Il'icheva
T N
TN
Kurskaia
O G
OG
Kolodiĭ
K M
KM
Iasinskaia
L M
LM
Durymanov
A G
AG
Ignashkina
M B
MB
Zaĭkovskaia
A V
AV
Shestopalov
A M
AM
Drozdov
I G
IG
D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000276:immunology / Q000302:isolation & purification*; D007251:Influenza, Human / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D016036:Seroepidemiologic Studies; D012800:Siberia / Q000453:epidemiology
D000914:Antibodies, Viral