title: Echocardiographic measurement of epicardial adipose tissue in obese children.
abstract: The echocardiographic measurement of epicardial adipose tissue (EAT) has been suggested as an easy method for evaluation of the visceral adipose tissue and its related cardiovascular risks in adults. However, a direct effect of obesity on cardiac function is not well established, and echocardiographic EAT thickness has not been studied in children. The aims of this study were to evaluate cardiac function and echocardiographic EAT thickness and to correlate EAT with the other echocardiographic findings in obese children. The study population included 106 obese and 62 lean children. Echocardiographic indexes of systolic and diastolic function were obtained. We measured EAT thickness on the free wall of the right ventricle from parasternal long-axis views. The septal and posterior wall thicknesses, relative wall thickness, left atrial diameter, and left ventricular mass were increased (p = 0.001) in obese children. However, systolic and diastolic functions of the left ventricle were normal in the patients. The obese children had a significantly thicker EAT (p = 0.001) compared to the lean subjects. EAT thickness correlated significantly with body mass index (r = 0.50, p = 0.001), left atrial diameter (r = 0.37, p = 0.001), and left ventricular mass (r = 0.33, p = 0.001). In conclusion, the present study demonstrates a close relationship between EAT thickness and obesity in children. Assessment of EAT thickness in routine echocardiographic examinations might be used as a feasible and reliable method for the evaluation of obesity and its related cardiovascular risks during childhood.
authors.affiliation: Department of Paediatric Cardiology, Kecioren Training and Research Hospital, Sanatoryum Caddesi, Pinarbasi Mahallesi, Ardahan Sokak, Kecioren Egitim ve Arastirma Hastanesi, Ankara, Turkey. pedkard@gmail.com
authors.forename: Osman
authors.initials: O
authors.lastname: Ozdemir
authors.forename: Samil
authors.initials: S
authors.lastname: Hizli
authors.forename: Ayhan
authors.initials: A
authors.lastname: Abaci
authors.forename: Kadir
authors.initials: K
authors.lastname: Agladioglu
authors.forename: Sinef
authors.initials: S
authors.lastname: Aksoy
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D015992:Body Mass Index; D002648:Child; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D010496:Pericardium / Q000000981:diagnostic imaging*; D011379:Prognosis; D012307:Risk Factors; D018754:Ventricular Dysfunction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology
references.citation: J Cardiol. 1995 Aug;26(2):135-6
references.pmid: 7674144
references.citation: Pediatrics. 2004 Aug;114(2 Suppl 4th Report):555-76
references.pmid: 15286277
references.citation: J Am Coll Cardiol. 2006 Jun 6;47(11):2267-73
references.pmid: 16750694
references.citation: Comp Biochem Physiol B. 1989;94(2):225-32
references.pmid: 2591189
references.citation: Am J Clin Nutr. 2000 Oct;72(4):1032-9
references.pmid: 11010948
references.citation: JAMA. 2004 Jun 16;291(23):2847-50
references.pmid: 15199035
references.citation: Pediatr Res. 2008 Aug;64(2):205-9
references.pmid: 18391840
references.citation: Am J Cardiol. 1994 Mar 15;73(8):613-5
references.pmid: 8147313
references.citation: Nat Clin Pract Cardiovasc Med. 2005 Oct;2(10):536-43
references.pmid: 16186852
references.citation: J Clin Endocrinol Metab. 2003 Nov;88(11):5163-8
references.pmid: 14602744
references.citation: Bull World Health Organ. 2007 Sep;85(9):660-7
references.pmid: 18026621
references.citation: Circulation. 1998 May 19;97(19):1907-11
references.pmid: 9609083
references.citation: Indian Heart J. 2007 Mar-Apr;59(2):142-6
references.pmid: 19122247
references.citation: Pediatr Cardiol. 2001 Jul-Aug;22(4):273-8
references.pmid: 11455391
references.citation: Obes Rev. 2007 May;8(3):253-61
references.pmid: 17444966
references.citation: Am J Clin Nutr. 1997 Jun;65(6):1703-8
references.pmid: 9174463
references.citation: Int J Cardiol. 1994 Aug;46(1):7-13
references.pmid: 7960279
references.citation: Am J Biomed Sci. 2009 Apr 1;1(2):133
references.pmid: 20098632
references.citation: Am J Cardiol. 2006 Sep 1;98(5):691-3
references.pmid: 16923463
references.citation: Pediatrics. 1999 Jun;103(6 Pt 1):1175-82
references.pmid: 10353925
references.citation: J Pediatr. 2006 Mar;148(3):321-5
references.pmid: 16615959
references.citation: Am J Clin Nutr. 1996 Jan;63(1):4-14
references.pmid: 8604668
references.citation: Am J Cardiol. 2004 Oct 15;94(8):1084-7
references.pmid: 15476634
references.citation: Turk J Pediatr. 2005 Jan-Mar;47(1):34-8
references.pmid: 15884627
references.citation: J Pediatr Endocrinol Metab. 2006 Aug;19(8):1007-14
references.pmid: 16995586
references.citation: AJR Am J Roentgenol. 1985 Oct;145(4):753-5
references.pmid: 3898784
references.citation: Circulation. 1981 Sep;64(3):477-82
references.pmid: 7261280
references.citation: Circulation. 2008 Mar 4;117(9):1216-27
references.pmid: 18316498
references.citation: Am J Cardiol. 2008 Dec 15;102(12):1602-7
references.pmid: 19064012
references.citation: J Am Coll Cardiol. 2008 Apr 8;51(14):1342-8
references.pmid: 18387434
references.citation: Pediatr Diabetes. 2006 Feb;7(1):39-44
references.pmid: 16489973
references.citation: Circulation. 1978 Dec;58(6):1072-83
references.pmid: 709763
references.citation: Eur Heart J. 2004 Jun;25(11):987-92
references.pmid: 15172471
references.citation: Int J Obes (Lond). 2009 Apr;33(4):440-6
references.pmid: 19223846
references.citation: Ultrasound Med Biol. 2000 Feb;26(2):229-37
references.pmid: 10722912
references.citation: Am J Cardiol. 2004 Jun 15;93(12):1567-9
references.pmid: 15194041