Multilocus sequence types of carbapenem-resistant Pseudomonas aeruginosa in Singapore carrying metallo-beta-lactamase genes, including the novel bla(IMP-26) gene.
Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from an earlier study showed that the epidemic clones from 2000 have not become established.
Koh
Tse Hsien
TH
Department of Pathology, Singapore General Hospital, Singapore. koh.tse.hsien@sgh.com.sg
Khoo
Cheng Teng
CT
Tan
Thuan Tong
TT
Arshad
Mohamed Amir Bin Mohamed
MA
Ang
Li Ping
LP
Lau
Lee Jin
LJ
Hsu
Li-Yang
LY
Ooi
Eng Eong
EE
D001426:Bacterial Proteins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D015780:Carbapenems / Q000494:pharmacology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics; D017422:Sequence Analysis, DNA / Q000379:methods; D012846:Singapore; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics*
D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases
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