Tumors associated with avian leukosis virus subgroup J in layer hens during 2007 to 2009 in China.
In the 3 years leading up to November 2009, 6 different types of naturally occurring neoplasms associated with avian leukosis virus subgroup J (ALV-J) were diagnosed by histopathology, polymerase chain reaction (PCR) and immunohistochemistry (IHC) in 140 layer hens out of approximately 100,000. The most prevalent tumor type was hemangioma (50%) in commercial layer flocks; the second most prevalent neoplasm type was myelocytoma (38.6%); a small number of ALV-J positive lymphomas (4.3%) that were not associated with Marek's disease (MD) or lymphoid leukosis (LL) was observed. Histiocytic sarcomas (2.1%) were found mainly in the spleen, liver and kidney. Fibrosarcomas (2.8%) presented as metastatic thigh, liver, lung and kidney neoplasms. Three cases of intestinal adenocarcinoma (2.1%) were found associated with ALV-J. Chickens with multiple tumors were a common phenomenon. Usually, hemangiomas plus myelocytomas (8.6%), myelocytomas plus histiocytic sarcomas (2.1%), hemangioma plus myelocytoma and lymphoma (3.6%) were found in various viscera organs. The present report describes the occurrence of multiple neoplasms associated with ALV-J in field layer hens.
Cheng
Ziqiang
Z
College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, PR China. czqsd@126.com
Liu
Jianzhu
J
Cui
Zhizhong
Z
Zhang
Li
L
D000818:Animals; D001353:Avian Leukosis / Q000453:epidemiology*; D001354:Avian Leukosis Virus / Q000235:genetics / Q000472:pathogenicity*; D002645:Chickens; D002681:China / Q000453:epidemiology; D017931:DNA Primers; D005260:Female; D006391:Hemangioma / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary; D054747:Histiocytic Sarcoma / Q000453:epidemiology / Q000662:veterinary; D007414:Intestinal Neoplasms / Q000453:epidemiology / Q000662:veterinary; D007680:Kidney Neoplasms / Q000453:epidemiology / Q000662:veterinary; D007951:Leukemia, Myeloid / Q000453:epidemiology / Q000662:veterinary; D008113:Liver Neoplasms / Q000453:epidemiology / Q000662:veterinary; D010058:Oviposition; D011201:Poultry Diseases / Q000453:epidemiology*; D013160:Splenic Neoplasms / Q000453:epidemiology / Q000662:veterinary
D017931:DNA Primers