title: [Feasibility study of using Sabin-IPV immunization in post-eradication era in China].
abstract: Based upon the World Health Organization (WHO)'s perspective, the post-eradication era is coming with a priority of global certifying the wild poliovirus eradication, by which then the Oral Poliomyelitis Attenuated Live Vaccine (OPV) will be ceased and Inactivated Poliovirus Vaccine (IPV) will be synchronized used, in particular the affordable Sabin-IPV (sIPV) is recommended to be used continuously in developing countries till the final eradication of poliomyelitis. However, no any sIPV has successfully been developed in the world. In this paper, the sIPV immunization strategy, current development status and its usage in industrialized countries are preliminarily analyzed. Feasibility analysis of potential sIPV usage in China, including immunization strategy, schedule, production technology and supply capacity is analysed as well. sIPV development in China should be accelerated in order to prepare production technology to the post-eradication era.
authors.affiliation: Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, Yunnan, China.
authors.forename: Yan-Chun
authors.initials: YC
authors.lastname: Che
authors.forename: Li
authors.initials: L
authors.lastname: Jiang
authors.forename: Cong-Wen
authors.initials: CW
authors.lastname: Shao
mesh_terms: D002681:China; D005240:Feasibility Studies; D006801:Humans; D038622:Internationality; D032541:Mass Vaccination / Q000379:methods*; D011055:Poliovirus Vaccine, Oral / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000276:immunology; D014944:World Health Organization
chemical_list: D011055:Poliovirus Vaccine, Oral; D014613:Vaccines, Attenuated