Bone marrow involvement in a patient with paracoccidioidomycosis: a rare presentation of juvenile form.
Paracoccidioides brasiliensis rarely shows bone marrow involvement and its response to treatment with itraconazole in children needs further assessment. We describe here a child with a juvenile disseminated form of paracoccidioidomycosis, which showed reticuloendothelial system involvement and the presence of Paracoccidioides brasiliensis in the bone marrow. The patient showed an effective and rapid response to itraconazole therapy.
Pereira
Graziella Hanna
GH
Department of Infectious Diseases and Infection Control, Brigadeiro Hospital, São Paulo, SP, Brazil. ghpereira1@terra.com.br
Santos
Aline Queiroz
AQ
Park
Miriam
M
Muller
Patricia Rady
PR
Padua
Soraia
S
Marchesi
Raquel Ferrari
RF
Aldred
Vera Lucia
VL
D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000382:microbiology* / Q000473:pathology; D002648:Child; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008198:Lymph Nodes / Q000473:pathology; D008853:Microscopy; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000188:drug therapy; D016896:Treatment Outcome
D000935:Antifungal Agents; D017964:Itraconazole
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