title: Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates.
abstract: The assembly of double-stranded (ds) DNA nanocircles both by hybridization with branched oligodeoxynucleotides (ODNs) and by intercalation was analyzed by atomic force microscopy (AFM). Branched ODNs ligated to single-stranded (ss) gap regions of dsDNA nanocircles led to defined, dumbbell-shaped architectures. ODNs containing an aromatic intercalator yielded oligomeric aggregates.
authors.affiliation: LIMES Institute, Chemical Biology & Medicinal Chemistry Unit, University of Bonn, 53121 Bonn, Germany.
authors.forename: Damian
authors.initials: D
authors.lastname: Ackermann
authors.forename: Goran
authors.initials: G
authors.lastname: Rasched
authors.forename: Sandeep
authors.initials: S
authors.lastname: Verma
authors.forename: Thorsten L
authors.initials: TL
authors.lastname: Schmidt
authors.forename: Alexander
authors.initials: A
authors.lastname: Heckel
authors.forename: Michael
authors.initials: M
authors.lastname: Famulok
mesh_terms: D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D018625:Microscopy, Atomic Force; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*
chemical_list: D009838:Oligodeoxyribonucleotides; D004247:DNA