Mohs' micrographic surgery for dermatofibrosarcoma protuberans.
BACKGROUND
Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue tumour with a high local recurrence rate. Recent reports indicate more favourable cure rates with Mohs' micrographic surgery (MMS).


OBJECTIVE
To investigate the beneficial use of MMS for DFSP in a single institution in Korea.


METHODS
A retrospective review was performed of pertinent demographic data, tumour data, treatment characteristics and follow-up data of 11 patients between 1997 and 2007. A review of literature for treatment methods and recurrence rates of DFSP was also performed.


RESULTS
In total, 11 patients (7 female, 4 male; mean age 26.9 years, range 3-36) with DFSP were identified and analysed. A mean number of 1.8 MMS layers were required to clear the tumour. All tumours were excised and reconstructed by the surgeon. There were no identifiable recurrences in the follow-up period of an average of 26 months.


CONCLUSIONS
Treatment of primary and recurrent DFSP by MMS results in a low recurrence rate with possible benefits of smaller defects compared with wide local excision. This study provides further support for MMS as the treatment of choice for DFSP.
Roh
M R
MR
Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Bae
B
B
Chung
K Y
KY
D000328:Adult; D002675:Child, Preschool; D018223:Dermatofibrosarcoma / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D015580:Mohs Surgery / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D056910:Republic of Korea; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult