[Secondary osteoporosis UPDATE. Bone metabolic change and osteoporosis during pregnancy and lactation].
Calcium transfer from the mother to the infant during pregnancy and lactation plays an extremely important role in the bone health of the mother and neonate. Calcium aids in bone health through all ages but is especially crucial during pregnancy and lactation. Changes in the structure and metabolism of bone during pregnancy and the early stage of postpartum are evaluated by investigating bone mineral density (BMD), bone histomorphometry and bone markers of human or animal models. The bone resorption increased at the end of pregnancy and lactation, and the bone formation increases and the bone structure is almost recovered after cessation of lactating in postpartum. Puerperal BMD remained static over the subsequent 5-10 years. If the women have a low BMD at this stage of their reproductive life, it tends not to improve over this time. Perhaps identification of this at-risk group may lead to effective interventions to reduce fracture risk in later life.
Kurabayashi
Takumi
T
Department of Obatetrics and Gynecology, Niigata City General Hospital.
Tamura
Ryo
R
Hata
Yuki
Y
Nishijima
Shota
S
Tsuneki
Ikunosuke
I
Tamura
Masaki
M
Yanase
Toru
T
D000328:Adult; D000818:Animals; D001862:Bone Resorption; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007774:Lactation / Q000378:metabolism*; D010012:Osteogenesis; D010024:Osteoporosis / Q000209:etiology* / Q000517:prevention & control; D049590:Postpartum Period / Q000378:metabolism; D011247:Pregnancy / Q000378:metabolism*; D051381:Rats; D012306:Risk; D014807:Vitamin D / Q000378:metabolism; D055815:Young Adult
D014807:Vitamin D