title: Late effects in hemopoiesis and bone tissue among people with incorporated osteotropic isotope 90Sr.
abstract: The present paper focuses on the analysis of data resulting from 50-y studies involving assessment of the hemopoiesis state in Techa riverside residents chronically exposed to radiation and evaluation of the bone tissue status for people with Sr incorporation at late time after the intakes.
  
  
  CONCLUSIONS
  1. In the late period after the start of chronic radiation exposure (50 y later) only a few individuals with red bone marrow doses reaching about 1.8 Gy (mean dose of 0.66 Gy) had a marked peripheral blood leucopenia, and the incidence of neutropenia, lymphopenia and thrombocypenia in the exposed group did not exceed that noted in the control group. The results of our observations indicate the spontaneous recovery of the hemopoietic system of residents of the Techa riverside villages. Thus, the adaptation mechanisms of hemopoiesis to the long-term chronic exposure in the range of low to intermediate doses are sufficiently effective; 2. About half of the people with Sr incorporation and the control group have changes in bone tissue expressed by different stages of osteoporosis. Age is a determinative factor of bone tissue involution in women while some tendency of Sr influence on the intensity of osteoporosis is revealed in the male group.
authors.affiliation: Urals Research Center for Radiation Medicine, 68-a Vorovsky St, 454076 Chelyabinsk, Russia.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Akleyev
authors.forename: Georgy P
authors.initials: GP
authors.lastname: Dimov
authors.forename: Tatyana A
authors.initials: TA
authors.lastname: Varfolomeyeva
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000528:radiation effects; D001842:Bone and Bones / Q000528:radiation effects*; D016022:Case-Control Studies; D004781:Environmental Exposure; D005260:Female; D006410:Hematopoiesis / Q000528:radiation effects*; D006801:Humans; D007970:Leukopenia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000209:etiology; D012426:Russia; D013326:Strontium Radioisotopes / Q000009:adverse effects*; D014875:Water Pollutants, Radioactive
chemical_list: D013326:Strontium Radioisotopes; D014875:Water Pollutants, Radioactive