Report of a case of Zimmermann-Laband syndrome with new manifestations.
Zimmermann-Laband syndrome is a rare disorder characterized by gingival fibromatosis, abnormalities of the nose and/or ears, absence and/or hyperplasia of the nails or terminal phalanges of the hands and feet, hyperextensibility of joints, hepatosplenomegaly, mild hirsutism and mental retardation. The syndromic characteristics of Zimmermann-Laband syndrome are highly variable and complicated. This paper described a patient with Zimmermann-Laband syndrome with new manifestations and discusses the possible underlying genetic mechanisms.
Lin
Z
Z
Department of Oral and Dentomaxillofacial Radiology, Affiliated Stomatology Hospital of Medical School, Nanjing University, China.
Wang
T
T
Sun
G
G
Huang
X
X
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000235:genetics / Q000628:therapy; D002648:Child; D019465:Craniofacial Abnormalities / Q000000981:diagnostic imaging / Q000235:genetics / Q000628:therapy; D005260:Female; D005351:Fibromatosis, Gingival / Q000000981:diagnostic imaging / Q000235:genetics / Q000628:therapy; D005355:Fibrosis; D005893:Gingivoplasty; D006228:Hand Deformities, Congenital / Q000000981:diagnostic imaging / Q000235:genetics / Q000628:therapy; D006801:Humans; D006965:Hyperplasia; D007621:Karyotyping; D011859:Radiography; D012008:Recurrence; D012086:Reoperation; D013950:Thymus Gland / Q000473:pathology*; D014096:Tooth, Supernumerary / Q000175:diagnosis* / Q000000981:diagnostic imaging; D016896:Treatment Outcome