title: The intestinal microbiota in inflammatory bowel diseases: time to connect with the host.
abstract: OBJECTIVE
  The aim of this review is to report recent findings regarding the role of the gut microbiota in inflammatory bowel disease pathogenesis.
  
  
  RESULTS
  After a description of the current knowledge on inflammatory bowel diseases-associated dysbiosis, we will focus on the recent functional studies that analyzed the cross relationship between the gut microbiota and the host.
  
  
  CONCLUSIONS
  Recently published studies have provided an insight into the altered dialog between the intestinal microbiota and the host leading to gut inflammation. Further investigation will allow identifying new therapeutic targets either in the microbiota or the host.
authors.affiliation: Gastroenterology and Nutrition Department, Saint Antoine Hospital, Université Pierre et Marie Curie, Paris VI, AP-HP, Paris, France. sokol_harry@yahoo.fr
authors.forename: Harry
authors.initials: H
authors.lastname: Sokol
authors.forename: Philippe
authors.initials: P
authors.lastname: Seksik
mesh_terms: D000818:Animals; D018407:Bacterial Physiological Phenomena; D054884:Host-Pathogen Interactions; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000276:immunology / Q000382:microbiology*; D007422:Intestines / Q000276:immunology / Q000382:microbiology*; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology