title: [Is there any scientific evidence supporting antiaging medicine?].
abstract: The objective of antiaging medicine is to interfere in the normal human biological aging process. Is there any scientific basis to justify classifying antiaging medicine as a medical specialty and not a branch of basic biological science? This review evaluated 110 papers, nine of which (8.2% of the total) reported studies involving human subjects. Only one of these studies was randomized and double-blinded (Jadad 2). In accordance with their classification of recommendations and level of evidence, these studies were considered CII. Three of the nine articles were published in journals with an impact factor over 1.110. Therefore, there does not appear to be any solid scientific and/or clinical evidence that would justify the application of antiaging medicine in current medical practice.
authors.affiliation: Hospital Geriátrico e de Convalescentes Dom Pedro II, Departamento de Clinica Medica, Sao Paulo, Brasil. hdp.dirtec@santacasasp.org.br <hdp.dirtec@santacasasp.org.br>
authors.forename: Milton Luiz
authors.initials: ML
authors.lastname: Gorzoni
authors.forename: Sueli Luciano
authors.initials: SL
authors.lastname: Pires
mesh_terms: D000375:Aging; D000818:Animals; D019317:Evidence-Based Medicine; D006801:Humans; D008511:Medicine; D012060:Rejuvenation