[Functional state of arterioles in patients with essential hypertension and arterial hypertension developed at the background of diabetes mellitus].
With the aim of studying linear velocity characteristics of arteriolar blood flow and reactivity of arterioles we examined 80 patients with essential arterial hypertension (AH), 83 patients with type 2 diabetes mellitus (DM) with concomitant AH, and 63 healthy people. In all patients examination included ultrasound continuous wave dopplerography of microcirculatory vascular bed at rest and after distant warming test. It was found that in patients with essential AH blood flow velocity in arterioles was maximal, increment of arteriolar blood flow in response to warming was lower than in healthy persons. In patients with type 2 DM minimal linear velocity characteristics of arteriolar blood flow and its increment in response to warming test were minimal. Results of the study evidence for principal differences of functioning and reactivity of arterioles in patients with essential AH and AH developed at the background of diabetes mellitus.
Volkov
V S
VS
State Medical Academy, ul. Sovetskaya 4, 170642 Tver, Russia.
Rudenko
E V
EV
D001160:Arterioles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008875:Middle Aged; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler