title: [Case for diagnosis. Langerhans cell histiocytosis].
abstract: Langerhans cell histiocytosis is a rare disease of unknown cause, characterized by the proliferation of histiocytic cells (Langerhans cells). Its diagnosis is especially difficult due to its wide clinical spectrum, ranging from a single lesion to a multisystemic disorder. Diagnosis may be confirmed by means of an immunohistochemical study. Treatment depends upon the severity of the disease, and systemic chemotherapy may be needed.
authors.affiliation: Faculdade de Medicina de Jundiaí, SP, Brasil.
authors.forename: Carolina Balbi
authors.initials: CB
authors.lastname: Mosqueira
authors.forename: Augusto Frederico de Paula
authors.initials: AF
authors.lastname: Xavier
authors.forename: Cíntia Letícia
authors.initials: CL
authors.lastname: Tuschinski
authors.forename: Clóvis A Lopes
authors.initials: CA
authors.lastname: Pinto
authors.forename: Paulo R
authors.initials: PR
authors.lastname: Cunha
mesh_terms: D000293:Adolescent; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D012871:Skin Diseases / Q000473:pathology*