Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA).
OBJECTIVE
We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea.


METHODS
In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht(2)) (kg/m(2)) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area >or=100 cm(2).


RESULTS
The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht(2); however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% CI 4.45-15.40]) than the obese (5.51 [2.81-10.80]) or sarcopenic group (2.64 [1.08-6.44]).


CONCLUSIONS
SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.
Lim
Soo
S
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kim
Jung Hee
JH
Yoon
Ji Won
JW
Kang
Seon Mee
SM
Choi
Sung Hee
SH
Park
Young Joo
YJ
Kim
Ki Woong
KW
Lim
Jae Young
JY
Park
Kyong Soo
KS
Jang
Hak Chul
HC
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D044466:Asian People / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology*; D009765:Obesity / Q000208:ethnology*; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D055948:Sarcopenia / Q000208:ethnology*; D017678:Sex Distribution
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