[Bilateral deafness and unilateral facial nerve palsy as presenting features of Wegener's granulomatosis : a case report].
A 72-year-old female patient presented with otitis of her left ear with inner ear depletion. Despite administration of intravenous antibiotics according to the resistogram and mastoidectomy the patient developed a similar pathological condition in the right ear and facial nerve palsy on the left side. Treatment with trimethoprim/sulfamethoxazole under the working diagnosis of a localised seronegative Wegener's granulomatosis was initiated without achieving remission. Cyclophosphamide pulse therapy in combination with high-dose methylprednisolone was initiated with rapid cure of the bilateral otitis. Sensorineural hearing loss and facial nerve palsy remained irreversible.
Bohne
S
S
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Lessingstr. 2, 07743, Jena, Deutschland. silvia.bohne@med.uni-jena.de
Koscielny
S
S
Burmeister
H P
HP
Guntinas-Lichius
O
O
Wittekindt
C
C
D000368:Aged; D020330:Bell Palsy / Q000175:diagnosis* / Q000209:etiology*; D003638:Deafness / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis*; D006801:Humans
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