title: Analyses of ERG in a patient with intraocular lymphoma.
abstract: OBJECTIVE
  To follow the changes in the electroretinograms (ERGs) in a patient with primary intraocular lymphoma (PIOL) who had a complete remission after chemotherapy.
  
  
  METHODS
  ERGs were recorded in a 41-year-old woman with PIOL during and after complete remission with chemotherapy. The patient was diagnosed with PIOL from both the ocular signs and the medical history of cranial lymphoma.
  
  
  RESULTS
  The ERGs were depressed in the subject. The amplitudes of the bright white flash b-waves were smaller than the a-waves, resulting in a "negative type" ERG. Six weeks after the beginning of chemotherapy, the ocular changes had resolved, and the ERGs, although not of the "negative type", still showed signs that the amplitude had not returned to normal levels.
  
  
  CONCLUSIONS
  The negative type ERGs indicated that the inner retina had been damaged to a greater extent than the outer retina. In the convalescent stage, when the ocular manifestations were resolved, the ERGs were still not fully recovered. Although only one case was studied, we suggest that ERGs can be used to evaluate and follow patients with a PIOL.
authors.affiliation: Department of Ophthalmology, Nagoya University School of Medicine, Nagoya, Japan.
authors.forename: Chieko
authors.initials: C
authors.lastname: Yasuda
authors.forename: Shinji
authors.initials: S
authors.lastname: Ueno
authors.forename: Mineo
authors.initials: M
authors.lastname: Kondo
authors.forename: Nagako
authors.initials: N
authors.lastname: Kondo
authors.forename: Chang-Hua
authors.initials: CH
authors.lastname: Piao
authors.forename: Hiroko
authors.initials: H
authors.lastname: Terasaki
references.citation: Int Ophthalmol Clin. 2002 Winter;42(1):115-31
references.pmid: 12189607
references.citation: Surv Ophthalmol. 2001 May-Jun;45(6):463-71
references.pmid: 11425352
references.citation: Invest Ophthalmol Vis Sci. 1989 Aug;30(8):1743-9
references.pmid: 2759790
references.citation: Cancer Control. 2004 Sep-Oct;11(5):285-95
references.pmid: 15377987
references.citation: Graefes Arch Clin Exp Ophthalmol. 2004 Nov;242(11):901-13
references.pmid: 15565454
references.citation: Ophthalmology. 1987 Dec;94(12):1631-9
references.pmid: 3323986
references.citation: Graefes Arch Clin Exp Ophthalmol. 2003 Oct;241(10):860-70
references.pmid: 14605902
references.citation: Doc Ophthalmol. 2004 Mar;108(2):107-14
references.pmid: 15455793
references.citation: Curr Opin Ophthalmol. 2002 Dec;13(6):411-8
references.pmid: 12441846
references.citation: Arch Ophthalmol. 1986 Jul;104(7):1013-20
references.pmid: 3488053