title: [Short-term therapeutic effect of modified total pelvic floor reconstruction in treatment of severe pelvic organ prolapse].
abstract: OBJECTIVE
  To evaluate short-term clinical effects of modified total pelvic floor reconstruction surgery in treatment of severe pelvic organ prolapse.
  
  
  METHODS
  Thirty-nine cases with severe pelvic organ prolapse including vault prolapse diagnosed by pelvic organ prolapse quantification (POP-Q) system received modified total pelvic floor reconstruction surgery. Clinical parameters associated peri-operative period and 12 months after surgery and complications were analyzed.
  
  
  RESULTS
  Median operation time was 70 minutes (30-240 minutes), median blood loss was 100 ml (10-200 ml). Seventy-seven percent (30/39) patients were able to micturate spontaneously in the next morning after surgery with postvoid residual volume less than 100 ml (0-650 ml). No severe intra-operative complications were recorded and the rate of postoperative morbidity was 20% (8/39). Median post-operative hospital stay was 4 days (1-11 days). The patients were followed up at median 24 months (13-29 months). According to POP-Q system evaluation, the successful rate of operation reached 100%. Two cases (5%, 2/39) were recorded as symptomatic recurrence which manifested as posterior wall prolapse within 24 months after operation. During follow-up, 8% (3/39) patients were found to have erosion within 7 months after surgery, and urgent urinary incontinence was observed in 5% (2/39) cases, while constipation occurred in 8% (3/39) cases. The most remarkable complication was dyspareunia (36%, 5/14); while 50% (7/14) experienced better sexual life after surgery.
  
  
  CONCLUSIONS
  Modified total pelvic reconstruction is a safe, efficient and micro-invasive surgery in treatment of severe pelvic organ prolapse. However, its influence on post-operative sexual life should be concerned.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Ren
authors.forename: Lan
authors.initials: L
authors.lastname: Zhu
authors.forename: Jing-he
authors.initials: JH
authors.lastname: Lang
authors.forename: Wen-yan
authors.initials: WY
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D004414:Dyspareunia / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D017773:Pelvic Floor / Q000601:surgery*; D056887:Pelvic Organ Prolapse / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D011788:Quality of Life; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000453:epidemiology / Q000209:etiology; D014596:Uterine Prolapse / Q000473:pathology / Q000601:surgery