Nucleosome positioning: an essential component of the enhancer regulatory code?
The organization of transcription factor binding sites within enhancers plays a key role in the function of these elements. A recent study suggests that the intrinsic propensity to bind to nucleosomes can also play a decisive part in determining enhancer function.
Ay
Ahmet
A
Department of Biochemistry and Molecular Biology, and Program in Quantitative Biology, Michigan State University, East Lansing, MI 48824, USA. ayahmet@msu.edu
Arnosti
David N
DN
D000818:Animals; D002938:Ciona intestinalis / Q000235:genetics; D004742:Enhancer Elements, Genetic / Q000502:physiology*; D050980:GATA Transcription Factors / Q000502:physiology; D005786:Gene Expression Regulation / Q000235:genetics / Q000502:physiology; D009707:Nucleosomes / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology
D050980:GATA Transcription Factors; D009707:Nucleosomes; D014157:Transcription Factors