Paraneoplastic retinopathy associated with retroperitoneal liposarcoma.
We report a case of paraneoplastic retinopathy associated with a retroperitoneal liposarcoma. A 42-year-old man was referred to our hospital with complaints of night blindness and blurred vision in the peripheral field. Electroretinograms showed a progressive amplitude reduction in his both eyes. Abdominal magnetic resonance imaging showed a large retroperitoneal mass, and pathologic examination revealed a dedifferentiated liposarcoma. Western blot analysis showed an antiretinal antibody in the serum of our patient, and his serum reacted with the photoreceptors of a bovine retina. To the best of our knowledge, this is the first case of paraneoplastic retinopathy associated with a liposarcoma.
Kondo
Mineo
M
Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan. kondomi@med.nagoya-u.ac.jp
Mokuno
Kumiko
K
Uemura
Ai
A
Kachi
Shu
S
Nakamura
Makoto
M
Kondo
Atsuya
A
Terasaki
Hiroko
H
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