title: The incidence of epiglottic cysts in a cohort of adults with acute epiglottitis.
abstract: OBJECTIVE
  To evaluate the effects of a coexisting epiglottic cyst on the clinical course and airway management of acute epiglottitis in adults. A review of the airway risk factors were studied in adults with acute epiglottitis in South Korea from 1997 to 2009.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Academic tertiary care referral medical center.
  
  
  METHODS
  The study included 117 adult patients that were diagnosed with acute epiglottitis laryngoscopically over a period of 12 years. Two distinct groups were identified: one with acute epiglottitis associated with an infected epiglottic cyst (n = 29, 25%) and the other with acute epiglotittis without a cyst (n = 88, 75%).
  
  
  METHODS
  Patient background data, clinical manifestations, laboratory data, airway management, outcomes, and recurrence were recorded.
  
  
  RESULTS
  Eight (28%) out of 29 patients with an infected epiglottic cyst required airway intervention compared to the four (5%) out of 88 patients without a cyst. The difference between the two groups was statistically significant (P = 0.001). Five out of six patients with recurrent acute epiglottitis had a coexisting epiglottic cyst. The recurrence of acute epiglottitis in patients with a cyst was significantly more frequent (P = 0.003). Twelve patients (10%) required airway intervention. There was no mortality found in this study. Logistic regression analysis showed that an older age, dyspnoea, a high pulse rate, and the presence of an epiglottic cyst were associated with an increased risk for airway obstruction.
  
  
  CONCLUSIONS
  The results of this study showed that a pre-existing epiglottic cyst might be associated with a suppurative infection of the supraglottis. Infected epiglottic cysts increased the risk for airway obstruction and recurrence of acute epiglottitis.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hwasun Hospital, Research Institute of Medical Sciences, Dong-Gu, Gwangju, South Korea.
authors.forename: T M
authors.initials: TM
authors.lastname: Yoon
authors.forename: J O
authors.initials: JO
authors.lastname: Choi
authors.forename: S C
authors.initials: SC
authors.lastname: Lim
authors.forename: J K
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003560:Cysts / Q000453:epidemiology* / Q000473:pathology; D004825:Epiglottis / Q000473:pathology*; D004826:Epiglottitis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult