title: The arms race between tomato and Fusarium oxysporum.
abstract: The interaction between tomato and Fusarium oxysporum f. sp. lycopersici has become a model system for the study of the molecular basis of disease resistance and susceptibility. Gene-for-gene interactions in this system have provided the basis for the development of tomato cultivars resistant to Fusarium wilt disease. Over the last 6 years, new insights into the molecular basis of these gene-for-gene interactions have been obtained. Highlights are the identification of three avirulence genes in F. oxysporum f. sp. lycopersici and the development of a molecular switch model for I-2, a nucleotide-binding and leucine-rich repeat-type resistance protein which mediates the recognition of the Avr2 protein. We summarize these findings here and present possible scenarios for the ongoing molecular arms race between tomato and F. oxysporum f. sp. lycopersici in both nature and agriculture.
authors.affiliation: Plant Pathology, Swammerdam Institute for Life Sciences, University of Amsterdam, P.O. Box 94215, 1090 GE Amsterdam, the Netherlands. f.l.w.takken@uva.nl
authors.forename: Frank
authors.initials: F
authors.lastname: Takken
authors.forename: Martijn
authors.initials: M
authors.lastname: Rep
mesh_terms: D005075:Biological Evolution; D005670:Fusarium / Q000235:genetics / Q000472:pathogenicity / Q000502:physiology*; D054884:Host-Pathogen Interactions / Q000235:genetics; D007113:Immunity, Innate / Q000235:genetics; D018551:Solanum lycopersicum / Q000235:genetics / Q000382:microbiology*; D014774:Virulence / Q000235:genetics
references.citation: Plant Cell. 2006 Aug;18(8):2082-93
references.pmid: 16844906
references.citation: FEMS Microbiol Lett. 2009 Nov;300(2):201-15
references.pmid: 19799634
references.citation: Annu Rev Genet. 1990;24:447-63
references.pmid: 2088175
references.citation: Plant Cell. 1998 Jun;10(6):1055-68
references.pmid: 9634592
references.citation: Plant J. 2000 Jul;23(2):183-93
references.pmid: 10929112
references.citation: Annu Rev Pathol. 2009;4:365-98
references.pmid: 18928408
references.citation: Curr Opin Plant Biol. 2000 Aug;3(4):299-304
references.pmid: 10873849
references.citation: Annu Rev Phytopathol. 2007;45:289-306
references.pmid: 17430087
references.citation: Mol Plant Microbe Interact. 2005 Jan;18(1):15-23
references.pmid: 15672814
references.citation: Mol Plant. 2008 May;1(3):401-10
references.pmid: 19825549
references.citation: FEMS Microbiol Lett. 2005 Dec 1;253(1):19-27
references.pmid: 16216445
references.citation: Science. 2007 Feb 23;315(5815):1098-103
references.pmid: 17185563
references.citation: Plant Cell. 2005 Apr;17(4):1268-78
references.pmid: 15749757
references.citation: Annu Rev Phytopathol. 2007;45:43-72
references.pmid: 17367271
references.citation: Annu Rev Plant Biol. 2009;60:379-406
references.pmid: 19400727
references.citation: J Mol Biol. 2004 Oct 8;343(1):1-28
references.pmid: 15381417
references.citation: Mol Plant Pathol. 2009 May;10(3):311-24
references.pmid: 19400835
references.citation: Plant Cell. 2002 Nov;14(11):2929-39
references.pmid: 12417711
references.citation: Curr Opin Plant Biol. 2007 Dec;10(6):580-6
references.pmid: 17884715
references.citation: PLoS Pathog. 2008 May 09;4(5):e1000061
references.pmid: 18464895
references.citation: Plant Physiol. 2006 Apr;140(4):1233-45
references.pmid: 16489136
references.citation: Science. 1939 Jun 30;89(2322):603-4
references.pmid: 17751616
references.citation: Science. 2009 May 8;324(5928):744-6
references.pmid: 19423813
references.citation: EMBO J. 2002 Sep 2;21(17):4511-9
references.pmid: 12198153
references.citation: Plant J. 2005 Jul;43(2):284-98
references.pmid: 15998314
references.citation: Curr Opin Plant Biol. 2009 Aug;12(4):427-36
references.pmid: 19394891
references.citation: Cell. 2006 Feb 24;124(4):803-14
references.pmid: 16497589
references.citation: Plant Cell. 2008 Aug;20(8):2009-17
references.pmid: 18723576
references.citation: Curr Opin Microbiol. 2005 Aug;8(4):399-404
references.pmid: 15996507
references.citation: Trends Plant Sci. 2002 Feb;7(2):67-71
references.pmid: 11832277
references.citation: Nature. 2006 Nov 16;444(7117):323-9
references.pmid: 17108957
references.citation: Phytopathology. 2003 Aug;93(8):1014-22
references.pmid: 18943868
references.citation: Mol Microbiol. 2004 Sep;53(5):1373-83
references.pmid: 15387816
references.citation: Plant J. 2009 Jun;58(6):970-8
references.pmid: 19228334
references.citation: Environ Microbiol. 2008 Jun;10(6):1475-85
references.pmid: 18312397
references.citation: Mol Plant Microbe Interact. 2009 Apr;22(4):371-80
references.pmid: 19271952
references.citation: Mol Genet Genomics. 2001 Aug;265(6):1104-11
references.pmid: 11523783
references.citation: Structure. 2009 Feb 13;17(2):172-82
references.pmid: 19217388
references.citation: Mol Plant Pathol. 2007 Mar;8(2):215-21
references.pmid: 20507493
references.citation: Nat Rev Mol Cell Biol. 2007 May;8(5):405-13
references.pmid: 17377525