title: Microwave-assisted Maillard reactions for the preparation of advanced glycation end products (AGEs).
abstract: The application of microwaves as an efficient form of volumetric heating to promote organic reactions was recognized in the mid-1980 s. It has a much longer history in the food research and industry where microwave irradiation was studied in depth to optimize food browning and the development of desirable flavours from Maillard reactions. The microwave-promoted Maillard reaction is a challenging synthetic method to generate molecular diversity in a straightforward way. In this paper we present a new rapid and efficient one-pot procedure for the preparation of pentosidine and other AGEs under microwave irradiation.
authors.affiliation: Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, via P. Giuria 9, 10125 Torino, Italy.
authors.forename: Sonja
authors.initials: S
authors.lastname: Visentin
authors.forename: Claudio
authors.initials: C
authors.lastname: Medana
authors.forename: Alessandro
authors.initials: A
authors.lastname: Barge
authors.forename: Valeria
authors.initials: V
authors.lastname: Giancotti
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Cravotto
mesh_terms: D001120:Arginine / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D017127:Glycation End Products, Advanced / Q000138:chemical synthesis* / Q000737:chemistry; D017612:Gold Compounds / Q000138:chemical synthesis / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry; D007202:Indicators and Reagents; D007700:Kinetics; D008239:Lysine / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry; D015416:Maillard Reaction / Q000528:radiation effects*; D013058:Mass Spectrometry; D008872:Microwaves
chemical_list: C523287:1,3-bis(5-amino-5-carboxypentyl)-4-methyl-1H-imidazolium; D017127:Glycation End Products, Advanced; D017612:Gold Compounds; D007093:Imidazoles; D007202:Indicators and Reagents; D001120:Arginine; C062187:pentosidine; D008239:Lysine