title: Psychoneuroimmunology: the example of psoriasis.
abstract: The relationship between the central nervous system (CNS) and the endocrine system have been known for many years. Indeed some of the hormone secreting glands are actually located in the brain. The notion that the CNS and hormones are also involved in the bi-directional cross-talk with the Immune System has been the target of intense research in the recent decades. In this manner, for example, psychological states can be closely related to changes in immune mediators, and not only they may influence the evolution of human diseases, but may in the future lead to novel therapeutic interventions. This is the subject of this review, with particular emphasis on the role of psychoneuroimmunology (PNI) in psoriasis.
authors.affiliation: Department of Psychiatry, University of Rochester, Rochester, NY, USA.
authors.forename: J
authors.initials: J
authors.lastname: Moynihan
authors.forename: E
authors.initials: E
authors.lastname: Rieder
authors.forename: F
authors.initials: F
authors.lastname: Tausk
mesh_terms: D016207:Cytokines / Q000502:physiology; D006801:Humans; D011565:Psoriasis / Q000276:immunology* / Q000523:psychology*; D013315:Stress, Psychological / Q000150:complications
chemical_list: D016207:Cytokines
references.citation: Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1059-64
references.pmid: 9927693
references.citation: J Am Acad Dermatol. 2001 Mar;44(3):433-8
references.pmid: 11209111
references.citation: J Psychosom Res. 2002 Oct;53(4):873-6
references.pmid: 12377296
references.citation: Nat Rev Immunol. 2005 Mar;5(3):243-51
references.pmid: 15738954
references.citation: J Am Acad Dermatol. 1986 Feb;14(2 Pt 1):305-11
references.pmid: 2419375
references.citation: Nature. 2007 Feb 8;445(7128):648-51
references.pmid: 17187052
references.citation: Dermatol Ther. 2008 Jan-Feb;21(1):22-31
references.pmid: 18318882
references.citation: Psychosom Med. 1998 Sep-Oct;60(5):625-32
references.pmid: 9773769
references.citation: J Clin Invest. 2008 Feb;118(2):597-607
references.pmid: 18202747
references.citation: Br J Clin Psychol. 2002 Jun;41(Pt 2):157-74
references.pmid: 12034003
references.citation: Brain Behav Immun. 2009 Nov;23(8):1109-16
references.pmid: 19615438
references.citation: Brain Behav Immun. 2007 May;21(4):374-83
references.pmid: 17360153
references.citation: Immunol Today. 1990 May;11(5):170-5
references.pmid: 2186751
references.citation: Dermatol Clin. 2005 Oct;23(4):681-94
references.pmid: 16112445
references.citation: Brain Behav Immun. 1990 Mar;4(1):67-73
references.pmid: 2334816
references.citation: Am J Clin Dermatol. 2005;6(6):383-92
references.pmid: 16343026
references.citation: Neurosci Biobehav Rev. 2010 Sep;35(1):2-16
references.pmid: 19822172
references.citation: Neuroscience. 2005;135(3):659-78
references.pmid: 16154288
references.citation: Am J Psychiatry. 2006 Sep;163(9):1630-3
references.pmid: 16946190
references.citation: Br J Psychiatry. 1983 Jul;143:51-4
references.pmid: 6882992
references.citation: J Clin Invest. 2006 May;116(5):1218-22
references.pmid: 16670765
references.citation: Biol Psychiatry. 2009 Feb 15;65(4):296-303
references.pmid: 18801471
references.citation: Hautarzt. 2005 May;56(5):466-72
references.pmid: 15711815
references.citation: Arch Dermatol. 2000 Mar;136(3):393-9
references.pmid: 10724204
references.citation: Am J Med. 2009 Dec;122(12):1150.e1-9
references.pmid: 19958894
references.citation: Psychosom Med. 2009 Feb;71(2):171-86
references.pmid: 19188531
references.citation: Clin Dermatol. 2007 Nov-Dec;25(6):563-7
references.pmid: 18021893
references.citation: Brain Behav Immun. 2007 Jan;21(1):92-9
references.pmid: 16714097
references.citation: Exp Gerontol. 2005 Apr;40(4):344-52
references.pmid: 15820616
references.citation: Ann N Y Acad Sci. 2003 May;992:205-17
references.pmid: 12794060
references.citation: Biol Psychiatry. 2001 Mar 1;49(5):391-404
references.pmid: 11274650
references.citation: Eur J Immunol. 1975 Apr;5(4):274-81
references.pmid: 61868
references.citation: Biol Psychiatry. 2009 May 1;65(9):732-41
references.pmid: 19150053
references.citation: J Invest Dermatol. 2008 May;128(5):1207-11
references.pmid: 18200064
references.citation: Brain Behav Immun. 2003 Oct;17(5):350-64
references.pmid: 12946657
references.citation: J Am Acad Dermatol. 1988 Sep;19(3):572-4
references.pmid: 3049703
references.citation: Prog Neuropsychopharmacol Biol Psychiatry. 2005 Feb;29(2):201-17
references.pmid: 15694227
references.citation: Psychosom Med. 2010 Feb;72(2):192-7
references.pmid: 20028830
references.citation: Acta Derm Venereol Suppl (Stockh). 1991;156:37-43
references.pmid: 2048373
references.citation: Ann N Y Acad Sci. 2009 Sep;1173:470-7
references.pmid: 19758188
references.citation: Ann N Y Acad Sci. 1998 May 1;840:747-54
references.pmid: 9629301
references.citation: Curr Opin Allergy Clin Immunol. 2007 Oct;7(5):374-81
references.pmid: 17873575
references.citation: J Affect Disord. 2009 Dec;119(1-3):181-5
references.pmid: 19269036
references.citation: Mol Psychiatry. 2006 Jul;11(7):680-4
references.pmid: 16491133
references.citation: Int J Dermatol. 1990 Jul-Aug;29(6):418-20
references.pmid: 2397964
references.citation: Psychother Psychosom. 1999;68(4):221-5
references.pmid: 10396014
references.citation: Psychoneuroendocrinology. 2006 May;31(4):439-46
references.pmid: 16359823
references.citation: Brain Behav Immun. 2009 Feb;23(2):149-58
references.pmid: 18793712
references.citation: Lancet. 2006 Jan 7;367(9504):29-35
references.pmid: 16399150
references.citation: Trends Immunol. 2006 Jan;27(1):24-31
references.pmid: 16316783
references.citation: J Dermatolog Treat. 2008;19(1):5-21
references.pmid: 18273720
references.citation: Biol Psychiatry. 2008 Jun 1;63(11):1022-9
references.pmid: 18242584
references.citation: Neurobiol Aging. 2005 Dec;26 Suppl 1:1-5
references.pmid: 16290269
references.citation: J Psychosom Res. 2001 Jan;50(1):11-5
references.pmid: 11259795
references.citation: Neuroimmunomodulation. 2005;12(5):255-69
references.pmid: 16166805
references.citation: Biol Psychiatry. 2007 Aug 15;62(4):280-1
references.pmid: 17678943
references.citation: J Am Acad Dermatol. 1996 Jun;34(6):1008-15
references.pmid: 8647966
references.citation: Neuroimmunomodulation. 2006;13(5-6):337-46
references.pmid: 17709956
references.citation: Biol Psychiatry. 2004 Dec 1;56(11):819-24
references.pmid: 15576057
references.citation: Ann N Y Acad Sci. 1998 Jun 30;851:311-35
references.pmid: 9668623
references.citation: J Am Acad Dermatol. 1993 Mar;28(3):488-9
references.pmid: 7680359
references.citation: Nat Med. 2007 Mar;13(3):242-4
references.pmid: 17342112
references.citation: Psychosom Med. 2002 Jan-Feb;64(1):15-28
references.pmid: 11818582
references.citation: Psychosom Med. 1975 Jul-Aug;37(4):333-40
references.pmid: 1162023
references.citation: Arch Gen Psychiatry. 2005 Dec;62(12):1377-84
references.pmid: 16330726
references.citation: Curr Pharm Des. 2005;11(8):963-72
references.pmid: 15777247