[Bioinformatic search for plant homologs of Ste20-like serine/threonine protein kinases].
Eleven plant homologs of animal and yeast Ste20-like protein kinases were identified. It was shown that the nearest plant homologs of the Ste20-like protein kinases are the unknown proteins A9RVK0 from Physcomitrella patens ssp. patens and A7P2E2 from Vitis vinifera. Cladistic analysis showed a protein kinase dstl from Dictyostelium discoideum as the closest protein to the newly found plant homologs. A predicted spatial structure of the A9RVK0 from P. patens ssp. patens catalytic domain is presented.
Karpov
P A
PA
Emets
A I
AI
Matusov
V G
VG
Nyporko
A Iu
AIu
Nadezhdina
E S
ES
Blium
Ia B
IaB
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D004023:Dictyostelium / Q000737:chemistry; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry* / Q000302:isolation & purification; D020930:MAP Kinase Kinase Kinases; D008969:Molecular Sequence Data; D010802:Phylogeny; D010940:Plant Proteins / Q000737:chemistry* / Q000302:isolation & purification; D010944:Plants / Q000201:enzymology; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry* / Q000302:isolation & purification; D017434:Protein Structure, Tertiary; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry* / Q000302:isolation & purification; D016415:Sequence Alignment; D040681:Structural Homology, Protein; D000099317:Hippo Kinases
D047908:Intracellular Signaling Peptides and Proteins; D020930:MAP Kinase Kinase Kinases; D010940:Plant Proteins; D017346:Protein Serine-Threonine Kinases; D029701:Saccharomyces cerevisiae Proteins; C485733:SLK protein, human; D000099317:Hippo Kinases; C078754:STE20 protein, S cerevisiae