title: Risk factors for infection after cardiovascular surgery in children in Argentina.
abstract: Infections after cardiovascular surgery are an important cause of morbidity and mortality. This paper described the study of risk factors associated with development of infections. This is a prospective study, setting in a Hospital JP Garrahan, a tertiary and referral center of Buenos Aires, Argentina. All patients with cardiac surgeries between 1/11/01 to 1/1/ 2002 were included. The median age of p was 30 months (r: 1-212 m), 184 p (53%) were boys, 21% (75) had underlying disease, being the genetic disorders or undernutrition the most frequent, 56 p (16%) had previous surgery, 36 p (10%) had received previous antibiotics and 30 (9%) of them had previous infection, An ASA score higher than or equal to 3 was found in 308 p (88%). Median hospital stay before surgery was 1 day (r1-120 d), 88 p (25%) needed inotropic support with epinephrine, 147 p (42%) needed mechanical ventilation during a median time of 4 days (r: 1-66d).Drainage with thorax opened was done in 339p (97%) for a median time of 2 days (r:1-7d). Total hospital stay was between 1 and 120 days (median 5 days). Postsurgical infections developed in 38 of 350p (11%). Superficial wound infection in 4 p (1%), 5 p (1.5%) had deep infection, 3p (1%) had mediastinitis and 26 p (7.5%) had other nonsurgical infections Eleven p (3%) died. By multivariate study underlying diseases (p<0.012) OR 4.22 (CI 1.38-12.8), inotropic support with epinephrine (p<0.027) OR 4.04 (CI 1.17-13.9) and postoperative stay longer than 12 days were found to be risk factors for infections. We concluded that presence of underlying diseases, longer hospitalization and inotropic support were risk factors for infections.
authors.affiliation: Hospital Garrahan, Buenos Aires, Argentina. margris2@yahoo.com.ar
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Rosanova
authors.forename: Adrian
authors.initials: A
authors.lastname: Allaria
authors.forename: Alejandro
authors.initials: A
authors.lastname: Santillan
authors.forename: Claudia
authors.initials: C
authors.lastname: Hernandez
authors.forename: Luis
authors.initials: L
authors.lastname: Landry
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Ceminara
authors.forename: Griselda
authors.initials: G
authors.lastname: Berberian
mesh_terms: D000293:Adolescent; D001118:Argentina; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000209:etiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric