Tuneable DNA-based asymmetric catalysis using a G-quadruplex supramolecular assembly.
Described is the first modular construction of a G-quadruplex chiral catalyst. The key objective was to use G-quadruplex structures to act as chiral ligands that would allow access to either enantiomer of the product of a Diels-Alder reaction.
Roe
Stephen
S
The School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Ritson
Dougal J
DJ
Garner
Tom
T
Searle
Mark
M
Moses
John E
JE
D002384:Catalysis; D002942:Circular Dichroism; D003300:Copper / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D054856:G-Quadruplexes; D006860:Hydrogen Bonding; D008024:Ligands; D013237:Stereoisomerism
D008024:Ligands; D003300:Copper; D004247:DNA