Even moderate weight loss can lower your heart risk.  Research shows that strength training and aerobic exercise can help sedentary seniors decrease their risk for insulin resistance.
D031204:Caloric Restriction; D004043:Dietary Fiber / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D015444:Exercise; D006331:Heart Diseases / Q000517:prevention & control*; D006801:Humans; D007333:Insulin Resistance; D009119:Muscle Contraction / Q000502:physiology; D053580:Muscle Strength / Q000502:physiology; D055070:Resistance Training; D012307:Risk Factors; D057185:Sedentary Behavior; D015431:Weight Loss
D004043:Dietary Fiber; D004044:Dietary Proteins