title: Use of Ir192 interstitial brachytherapy for an equine malignant dermal schwannoma.
abstract: A 10-year-old Hanoverian mare was evaluated for a right buccal swelling that recurred 3 months following surgical resection. Ultrasonographic examination showed a broadly pedunculated subcutaneous mass at the level of 106-109 and 406-409 cheek teeth associated with an erosive mucosal lesion on the inside of the cheek. Histological examination of a biopsy specimen revealed a well-demarcated, malignant, dermal schwannoma. Following subcutaneous placement of platinum coated Ir192 wires under general anaesthesia, low-dose radiation of 5 gray per day was delivered for 14 days. Short-term complications included loss of patency of the right nasolacrimal duct, erythema, dermatitis, leukotrichia and left-sided deviation of the muzzle. Ten months later, there has been no tumour recurrence. Findings suggest that the use of interstitial brachytherapy should be considered for a malignant, dermal schwannoma that has recurred or is not amenable to surgery.
authors.affiliation: Section of Equine Medicine, Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa. montague.saulez@up.ac.za
authors.forename: M N
authors.initials: MN
authors.lastname: Saulez
authors.forename: A
authors.initials: A
authors.lastname: Voigt
authors.forename: J C A
authors.initials: JC
authors.lastname: Steyl
authors.forename: E
authors.initials: E
authors.lastname: van Wilpe
authors.forename: J
authors.initials: J
authors.lastname: Kotzen
authors.forename: F
authors.initials: F
authors.lastname: Daniels
mesh_terms: D000818:Animals; D001918:Brachytherapy / Q000379:methods / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000473:pathology / Q000532:radiotherapy*; D006736:Horses; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D009442:Neurilemmoma / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D007496:Iridium Radioisotopes