Nuclear functions of actin.
Actin participates in several essential processes in the cell nucleus. Even though the presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes that require actin have been only recently identified. Actin is part of chromatin remodeling complexes; it is associated with the transcription machineries; it becomes incorporated into newly synthesized ribonucleoproteins; and it influences long-range chromatin organization. As in the cytoplasm, nuclear actin works in conjunction with different types of actin-binding proteins that regulate actin function and bridge interactions between actin and other nuclear components.
Visa
Neus
N
Department of Molecular Biology & Functional Genomics, Stockholm University, Sweden. Neus.Visa@molbio.su.se <Neus.Visa@molbio.su.se>
Percipalle
Piergiorgio
P
D000199:Actins / Q000502:physiology*; D002467:Cell Nucleus / Q000502:physiology*; D002843:Chromatin / Q000502:physiology; D003593:Cytoplasm / Q000502:physiology; D012321:DNA-Directed RNA Polymerases / Q000502:physiology; D034441:Heterogeneous-Nuclear Ribonucleoproteins / Q000502:physiology; D014158:Transcription, Genetic
D000199:Actins; D002843:Chromatin; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012321:DNA-Directed RNA Polymerases
Curr Opin Cell Biol. 2007 Jun;19(3):326-30
17467255
Nucleic Acids Res. 1993 Aug 25;21(17):4085-92
8371983
Genes Dev. 2005 Aug 15;19(16):1871-84
16103215
Exp Cell Res. 2004 Mar 10;294(1):140-8
14980509
Eur J Biochem. 1980 Sep;110(2):343-8
6254767
J Biol Chem. 2009 Feb 27;284(9):5753-62
19117945
Exp Cell Res. 1999 Aug 25;251(1):135-46
10438579
J Cell Biol. 2006 Mar 27;172(7):967-71
16549500
Biochem Cell Biol. 2009 Feb;87(1):283-306
19234542
Curr Opin Cell Biol. 2006 Jun;18(3):267-74
16574391
Curr Biol. 2002 Jan 8;12(1):13-25
11790299
J Cell Sci. 2004 May 15;117(Pt 12):2481-90
15128868
Nat Struct Mol Biol. 2005 Mar;12(3):238-44
15711563
Annu Rev Biochem. 2002;71:755-81
12045110
Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19199-204
19052240
FASEB J. 2006 Sep;20(11):1901-3
16877530
Cell. 1996 Jan 26;84(2):253-64
8565071
Mol Biol Cell. 2009 Aug;20(15):3543-51
19477923
Nat Cell Biol. 2009 Apr;11(4):451-9
19287377
Mol Biol Cell. 2003 Dec;14(12):4805-12
12960421
EMBO J. 1984 Oct;3(10):2363-71
6499833
J Cell Biol. 2006 Feb 13;172(4):541-52
16476775
J Cell Biochem. 2006 Nov 1;99(4):1001-9
16960872
Trends Cell Biol. 2004 Aug;14(8):435-42
15308210
FEBS Lett. 2008 Jun 18;582(14):2051-65
18375206
Neuron. 1990 May;4(5):711-23
2344408
J Cell Biol. 2001 Apr 2;153(1):229-36
11285288
Biochem Cell Biol. 2006 Aug;84(4):418-26
16936815
Biochemistry. 2007 Jul 31;46(30):8897-908
17620012
Nucleic Acids Res. 2002 Apr 15;30(8):1725-34
11937625
Curr Opin Cell Biol. 1999 Jun;11(3):363-71
10395553
Curr Biol. 2006 Apr 18;16(8):825-31
16631592
Science. 2000 Oct 13;290(5490):337-41
11030652
J Biol Chem. 2007 Jun 29;282(26):18872-8
17468105
Genes Dev. 2004 Dec 15;18(24):3010-5
15574586
Cell. 1984 Nov;39(1):111-22
6386181
Nat Cell Biol. 2004 Nov;6(11):1094-101
15502823
Cell. 2003 May 2;113(3):329-42
12732141
Cell. 1998 Nov 25;95(5):625-36
9845365
J Cell Sci. 2004 Oct 15;117(Pt 22):5333-41
15466884
J Cell Biol. 2007 Dec 17;179(6):1095-103
18070915
Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20291-6
19074261
Cell Mol Life Sci. 2009 Jul;66(13):2151-65
19300907
J Biol Chem. 2006 Jun 16;281(24):16264-71
16603771
Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2824-9
11880634
EMBO J. 1991 Apr;10(4):757-66
1849072
Exp Cell Res. 2003 May 15;286(1):12-21
12729790
Histochem Cell Biol. 2009 Jun;131(6):743-53
19294406
J Cell Sci. 2003 Oct 1;116(Pt 19):3949-56
12928329
Proc Natl Acad Sci U S A. 2003 May 27;100(11):6475-80
12743363
Trends Cell Biol. 2002 Sep;12(9):425-32
12220863
Mol Cell Biol. 2008 Oct;28(20):6342-57
18710935
Int Rev Cell Mol Biol. 2009;272:107-47
19121817
Nat Cell Biol. 2004 Dec;6(12):1165-72
15558034
J Biol Chem. 2003 Apr 18;278(16):14394-400
12566455
FEBS Lett. 2008 Jun 18;582(14):2120-7
18325339
Mol Biol Cell. 1999 Aug;10(8):2595-605
10436015
J Cell Biol. 2008 Mar 24;180(6):1061-4
18347069
Nat Rev Mol Cell Biol. 2003 Aug;4(8):605-12
12923522
RNA. 2002 Sep;8(9):1102-11
12358429
FEBS Lett. 2008 Jun 18;582(14):2041-50
18442483
Genes Dev. 2007 Dec 1;21(23):3027-43
18056419
Genes Dev. 2005 Jun 15;19(12):1401-15
15964991
J Cell Biol. 2001 Mar 5;152(5):895-910
11238447
J Struct Biol. 2002 Oct-Dec;140(1-3):3-9
12490148
J Biol Chem. 2007 Mar 9;282(10):7616-23
17220302
Science. 2001 Jun 8;292(5523):1863-76
11313498
Nat Methods. 2007 Nov;4(11):951-6
17922018
Methods Mol Biol. 2009;567:215-35
19588095
Chromosoma. 1990 Dec;100(1):37-47
2129286
Nat Cell Biol. 2006 Jul;8(7):756-63
16767080
FEBS Lett. 2008 Jun 18;582(14):2033-40
18423404
Nat Rev Mol Cell Biol. 2002 Mar;3(3):195-205
11994740
Mol Biol Cell. 2008 Jul;19(7):3008-19
18480411
PLoS Genet. 2008 Mar 21;4(3):e1000039
18369458
Annu Rev Biochem. 2003;72:573-608
14527325
Genes Dev. 1993 Mar;7(3):393-406
8449401
Genes Dev. 2008 Feb 1;22(3):322-30
18230700
FASEB J. 2010 Jan;24(1):146-57
19729515
Science. 2007 Jun 22;316(5832):1749-52
17588931
EMBO Rep. 2006 May;7(5):525-30
16514417
Trends Cell Biol. 2006 Aug;16(8):391-6
16828286