title: Interleukin 6 activity associated with a cardiac lymphoma.
abstract: Primary cardiac B-cell lymphoma is an extremely rare heart tumor that may be difficult to diagnose because of nonspecific clinical manifestations. Cardiac myxomas and mediastinal lymphomas show increased levels of serum cytokines, which correlate with symptoms and tumor size. We present a case of an intracardiac large B-cell lymphoma in a 75-year-old woman who had high serum levels of interleukin 6 that decreased after tumor excision. These data suggest a possible correlation between cardiac B lymphoma symptoms and interleukin 6 overproduction.
authors.affiliation: Division of Cardiac Surgery, University Hospital Le Scotte, Viale Bracci, Siena, Italy. chiavarelli@unisi.it
authors.forename: Mario
authors.initials: M
authors.lastname: Chiavarelli
authors.forename: Emma
authors.initials: E
authors.lastname: Borrelli
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Gandolfo
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D006348:Cardiac Surgical Procedures / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006338:Heart Neoplasms / Q000097:blood*; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000097:blood* / Q000601:surgery; D012720:Severity of Illness Index
chemical_list: D014408:Biomarkers, Tumor; D015850:Interleukin-6