Lithium-associated Mobitz II block: case series and review of the literature.
We report two cases of lithium-associated Mobitz II block. Both patients required placement of a permanent pacemaker due to persistent block and symptoms despite attempts at lowering the daily dose of lithium. We then reviewed the literature on this rare complication. Chronic lithium therapy may be associated with development of conduction block at or below the level of the atrioventricular node. Patients taking lithium should be monitored closely for development of cardiovascular complications.
Armstrong
Ehrin J
EJ
Department of Medicine, Division of Cardiology, University of California, San Francisco, California 94143-0124, USA. ehrin.armstrong@gmail.com
Dubey
Ankit
A
Scheinman
Melvin M
MM
Badhwar
Nitish
N
D001714:Bipolar Disorder / Q000188:drug therapy; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000139:chemically induced* / Q000628:therapy*; D006801:Humans; D018020:Lithium Compounds / Q000009:adverse effects*; D008875:Middle Aged; D010138:Pacemaker, Artificial
D018020:Lithium Compounds