Studies on resilin-like gene products in insects.
Putative pro-resilins from 12 Drosophila species are compared with each other and with some pro-resilin-related proteins from other insect species, in an attempt to decide which structural features are likely to be important for the characteristic properties of resilins. The putative pro-resilins from the 12 Drosophila species are very similar; their structures are characterized by a chitin-binding R&R Consensus sequence of type RR-2, surrounded by two repeat-containing regions. The repeat-containing regions are assumed to be responsible for the long-range elasticity characteristic for resilin. Pronounced differences are present between the Drosophila pro-resilins and the resilin-like gene products present in other insect species. It is suggested that gene products, which are predicted both to be cuticular proteins and to possess long-range elasticity, should be classified as either putative pro-resilins or pro-resilin-like proteins. Gene products which are predicted to possess long-range elasticity, but do not contain a chitin-binding region, should not be classified as pro-resilin-like proteins until it has been established that they are cuticular proteins.
Andersen
Svend Olav
SO
The Collstrop Foundation, The Royal Danish Academy of Sciences and Letters, H.C. Andersen Boulevard 35, 1553 Copenhagen V, Denmark. soa@royalacademy.dk
D020816:Amino Acid Motifs; D000818:Animals; D016384:Consensus Sequence; D004330:Drosophila / Q000235:genetics*; D029721:Drosophila Proteins / Q000737:chemistry* / Q000235:genetics; D019476:Insect Proteins / Q000737:chemistry* / Q000235:genetics; D007313:Insecta / Q000235:genetics; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein
D029721:Drosophila Proteins; D019476:Insect Proteins; C030951:resilin