Synthesis of gamma-lactone-type sialic acid, an isomer of 2,3-dehydrosialic acid.
An efficient synthesis of gamma-lactone-type sialic acid, which is an isomer of 2,3-dehydrosialic acid, was achieved from the corresponding sialic ester. The sialic ester was reconstructed from the gamma-lactone in a 95% yield. The gamma-lactone structure was determined by methylating to its corresponding methyl ether.
Sawada
Yoshiharu
Y
The United Graduate School of Agricultural Science, Gifu University, Gifu, Japan.
Nakatsuka
Shin-ichi
S
D007536:Isomerism; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D012794:Sialic Acids / Q000138:chemical synthesis* / Q000737:chemistry*
D007783:Lactones; D012794:Sialic Acids