[Complex application of indralin and ferrocin for the combined exposure on the organism of external gamma-irradiation and incorporation of 137Cs].
The summary of the study is that when using both medicines indraline doesn't influence the effectiveness of pherrocine in preventing of 137Cs accumulation in the main depositing/pooling organs. The radiation protecting medicine indraline used more intensive accumulation of radio nuclides in liver and kidney then a control. Accumulation rapidity and amount of 137Cs in liver and kidney depends on the time period between taking indraline and inflow of cesium into organism of animals. For the case when animals being exposured by external gamma-irradiation and incorporation of 137Cs the introduction of indraline without pherrocine is not advisable.
Zhorova
E S
ES
Kalistratova
V S
VS
Nisimov
P G
PG
Parfenova
I M
IM
Tishchenko
G S
GS
D000284:Administration, Oral; D000818:Animals; D021461:Animals, Outbred Strains; D000931:Antidotes / Q000627:therapeutic use*; D002588:Cesium Radioisotopes / Q000378:metabolism / Q000633:toxicity; D004333:Drug Administration Routes; D004359:Drug Therapy, Combination; D016061:Enterosorption; D005295:Ferrocyanides / Q000627:therapeutic use*; D005720:Gamma Rays; D007273:Injections, Intramuscular; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D018482:Muscle, Skeletal / Q000378:metabolism; D010636:Phenols / Q000627:therapeutic use*; D011832:Radiation Injuries / Q000188:drug therapy*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*
D000931:Antidotes; D002588:Cesium Radioisotopes; D005295:Ferrocyanides; D010636:Phenols; D011837:Radiation-Protective Agents; C086896:indralin; C042827:potassium iron(III) hexacyanoferrate (II); C000170:ferric ferrocyanide