title: [Analysis of safety and efficacy of laparoscopic and open partial nephrectomy for small renal cell carcinoma].
abstract: OBJECTIVE
  To compare the safety and efficacy of laparoscopic and open partial nephrectomy for small renal cell carcinoma.
  
  
  METHODS
  To collect and analyze the data such as operation time, warm ischemia time, complications, recovery and surgical margins of 110 patients of small renal carcinoma (T1aN0M0) from January 2004 to March 2009, 52 of which underwent laparoscopic partial nephrectomy (LPN) and the other 58 patients underwent open partial nephrectomy (OPN).
  
  
  RESULTS
  The mean operation time of LPN group and OPN group were 177.8 min and 126.7 min (t = 3.973, P < 0.01), respectively. The warm ischemia time of the two groups were 28.3 min and 21.9 min (t = 4.627, P > 0.05), respectively. Two cases in LPN group and 1 case in OPN group (3.8% vs 1.7%, chi(2) = 0.010, P > 0.05) needed blood transfusion. The increment of creatine after operation were 4 micromol/L in LPN group and 6 micromol/L in OPN group (t = -2.018, P > 0.05). Six cases (11.5%) in LPN group and 8 cases (13.8%) in OPN group needed collection system repairing (chi(2) = 0.130, P > 0.05)and the same data of hematuria after operation was observed. There was no urinary fistula or other severe complications in all patients. The hospital stay after operation was 10.6 d and 12.9 d (t = -3.244, P < 0.01) in the two groups, respectively. All surgical margins were negative.
  
  
  CONCLUSIONS
  LPN and OPN have the same safety and efficacy, LPN primary treatment can be used for selected patients of T1aN0M0 renal cell carcinoma because of its fast recovery.
authors.affiliation: Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, Beijing 100034, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Yao
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Zhou
authors.forename: Xue-song
authors.initials: XS
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Song
authors.forename: Ning-chen
authors.initials: NC
authors.lastname: Li
authors.forename: Zhi-song
authors.initials: ZS
authors.lastname: He
mesh_terms: D002292:Carcinoma, Renal Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D010535:Laparoscopy; D008297:Male; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome