Drug therapy of tuberculosis.
In new, previously untreated tuberculosis patients preference is given to treatment with major antituberculous drugs, namely Isoniazid, PAS and Streptomycin. The exchange of PAS with one of the recently introduced drugs (Rifampin, Ethambutol) should await the results of the therapeutic trials being conducted at various centers. In the meantime, these new drugs should be reserved for reactivation cases, for individuals hypersensitive to major antituberculous agents, or who are not responding satisfactorily to the routine therapy and for patients infected with organisms resistant to Isoniazid, PAS or Streptomycin.
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Tubercle. 1963 Mar;44:180-2
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Tubercle. 1969 Jun;50(2):125-43
4894707
Ann N Y Acad Sci. 1966 Apr 20;135(2):835-45
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