Executive functioning in adult patients with Sydenham's chorea.
Sydenham's chorea (SC) is characterized by a combination of motor and behavioral findings. Cognitive function has been scarcely studied in this condition. The aim of this study is to investigate executive functions in adult patients with SC. We performed neuropsychological tests to evaluate executive functions in controls and adult patients with persistent and in remission SC. Patients with SC have impairment in Tower of London task, reduced verbal fluency, and lower scores in the Stroop test. A subset of adult patients with SC present with executive dysfunction, even when chorea is in remission.
Beato
Rogério
R
Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Maia
Débora P
DP
Teixeira
Antônio Lúcio
AL
Cardoso
Francisco
F
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002819:Chorea / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D010868:Pimozide / Q000627:therapeutic use; D012720:Severity of Illness Index; D014635:Valproic Acid / Q000627:therapeutic use; D055815:Young Adult
D000900:Anti-Bacterial Agents; D018726:Anti-Dyskinesia Agents; D000927:Anticonvulsants; D010868:Pimozide; D014635:Valproic Acid; D010401:Penicillin G Benzathine