title: [Pulmonary involvement in patients with hypertensive disease].
abstract: METHODS
  Parameters of spirometry, body plethysmography, and pulmonary diffusion capacity were measured in 46 patients (age 35-60 years, 40 men, 6 women) with stage I-II hypertensive disease (HD) without bronchial and pulmonary diseases, systolic dysfunction of left ventricular myocardium, obesity, current or past smoking.
  
  
  RESULTS
  Increase of severity of HD and elevation of average values of arterial pressure (AP) was associated with mixed type worsening of parameters of pulmonary ventilation capacity. Negative correlations existed between parameters of 24 hour arterial pressure monitoring and spirometry. Progression of microalbuminuria and endothelial dysfunction was associated with lowering of pulmonary vital capacity, alveolar volume, and diffusion capacity.
  
  
  CONCLUSIONS
  The data presented allow to suggest that lungs can stand as target organ in hypertensive disease.
authors.affiliation: Kemerovo, Russia. olb61@mail.ru
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
authors.forename: N V
authors.initials: NV
authors.lastname: Rutkovskaia
authors.forename: S A
authors.initials: SA
authors.lastname: Smakotina
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Chesnokova
authors.forename: E V
authors.initials: EV
authors.lastname: Bazdyrev
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Cherniavskaia
authors.forename: I A
authors.initials: IA
authors.lastname: Kudriavtseva
mesh_terms: D000328:Adult; D001794:Blood Pressure; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010991:Plethysmography; D011379:Prognosis; D013147:Spirometry; D014797:Vital Capacity