A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain.
OBJECTIVE
This study describes the clinicopathological characteristics of a group of patients with oral lichen planus (OLP) in south-eastern Spain.


METHODS
A retrospective descriptive study was made of 550 patients clinically and histopathologically diagnosed with OLP in the period 1991-2007. Patient gender, age, the prevalence of hepatitis C, symptoms and malignization were recorded. The clinical forms were classified as reticular-papular and atrophic-erosive.


RESULTS
Of the 550 patients, 128 (23.3%) were men and 422 (76.7%) women. The mean age was 56.35 +/- 13.67 years (range 14-91). The prevalence of hepatitis C was 3.5%. The red clinical forms were the most frequent, with 359 cases (64.2%). The lesions were asymptomatic in 159 patients (28.9%). Five patients developed oral squamous cell carcinoma (0.9%); none of these subjects was smokers.


CONCLUSIONS
Patients with OLP present different clinical manifestations. Women were more frequently affected by the disease, and the malignant transformation rate was under 1%.
Bermejo-Fenoll
A
A
Mariano Sánchez-Siles, Clínica Odontológica Universitaria, Medicina Bucal, Hospital Morales Meseguer, Murcia, Spain.
Sánchez-Siles
M
M
López-Jornet
P
P
Camacho-Alonso
F
F
Salazar-Sánchez
N
N
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D017676:Lichen Planus, Oral / Q000145:classification / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology; D012189:Retrospective Studies; D013030:Spain; D055815:Young Adult