title: Changes in Health-Related Quality of Life among African-Americans in a lifestyle weight loss program.
abstract: OBJECTIVE
  Changes in health-related quality of life (HRQoL) were assessed in clinically obese, African-American adults after completion of a weight loss program that resulted in modest average weight loss.
  
  
  METHODS
  Data were analyzed for 87 men and women who provided weight measurements after an initial 10-week weight loss program (Phase 1) and a subsequent clinical trial to evaluate three weight maintenance approaches (Phase 2) over an additional 8 to 18 months. HRQoL was assessed using the Short Form SF-36 questionnaire. Intra-person changes in HRQoL were assessed and analyzed for associations with weight change within each phase. Non-parametric bivariable analyses and multivariable linear regression were used in statistical analyses.
  
  
  RESULTS
  Changes in HRQoL were modest; clinically significant intra-subject improvements in SF-36 domains of general health and vitality and in the mental component summary score were observed after Phase 1 but were attenuated during Phase 2. Improvements in vitality were significantly associated with greater weight loss in Phase 1, but no HRQoL change scores during Phase 2 were associated with weight change.
  
  
  CONCLUSIONS
  Short-term improvements in general health and vitality were observed. The vitality domain of the SF-36 appeared to be the domain of HRQoL most responsive to modest weight change.
authors.affiliation: Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA.
authors.forename: Aluko A
authors.initials: AA
authors.lastname: Hope
authors.forename: Shiriki K
authors.initials: SK
authors.lastname: Kumanyika
authors.forename: Justine
authors.initials: J
authors.lastname: Shults
authors.forename: William C
authors.initials: WC
authors.lastname: Holmes
mesh_terms: D000328:Adult; D001741:Black or African American; D001294:Attitude to Health; D005260:Female; D006293:Health Promotion / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011788:Quality of Life; D040242:Risk Reduction Behavior; D015431:Weight Loss / Q000208:ethnology*
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