Insular lesions and smoking cessation after first-ever ischemic stroke: a 3-month follow-up.
Little is known about biological factors involved in post-stroke smoking cessation. A recent retrospective study has indicated a possible association between unilateral insular lesions of various origin and a rapid disruption of nicotine addiction. Given the above, the aim of the present prospective study was to assess a relationship between post-stroke smoking cessation and lesion localization. Eighty-seven patients with first-ever, unilateral, ischemic stroke who had been active smokers at stroke onset were examined during hospitalization and at 3-month follow-up. No association was found between any specific lesion localization (the insula, operculum, striatum, thalamus, internal capsule, brainstem) and smoking status at the 3-month follow-up visit. Patients with lacunar circulation strokes (LACS) were more likely to be non-smokers at the follow-up examination. No sudden disruption of nicotine addition was observed in patients with insular or other stroke locations. Concluding, post-stroke smoking cessation may not be associated with insular lesions.
Bienkowski
Przemyslaw
P
Department of Pharmacology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Zatorski
Pawel
P
Baranowska
Anna
A
Ryglewicz
Danuta
D
Sienkiewicz-Jarosz
Halina
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology*; D002545:Brain Ischemia / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012907:Smoking / Q000473:pathology; D016540:Smoking Cessation; D020521:Stroke / Q000473:pathology; D013997:Time Factors