[Diabetes as a risk factor for infections in cirrhotic patients].
OBJECTIVE
Infections are a common cause of morbidity and mortality in cirrhotic patients. Diabetes Mellitus (DM) is a predisposing factor for infections, and coexistence of DM and cirrhosis has increased in the last years, particularly in cirrhosis caused by hepatitis C virus. The aim of this study was to determine if there is an association between DM and infections in patients with cirrhosis.


METHODS
Retrospective, cross sectional, analytical, multicenter study. Patients included were distributed in two groups: those with DM (glucose > 126 mg/dl) and those without DM. Frequency and type of infections were compared between both groups. Data was analyzed using Student's t test, Chi square, and Odds ratio analysis.


RESULTS
178 patients were included, 60.1% were male. Range age was between 25 and 88 years, and 25.8% reported DM. There were no demographic differences between groups. The frequency of infections in the DM group was 84.8% as compared to 48.5% in the controls (p=0.001; OR = 5.9). The most common infections were Urinary Tract Infection (UTI), Pneumonia, and Cellulites. We found a higher frequency of Pneumonia in the DM group, not so for UTI and Cellulites population.


CONCLUSIONS
The occurrence of DM is a risk factor for infections in patients with hepatic cirrhosis, particularly increased is the risk for acquiring Pneumonia.


BACKGROUND
Cirrhosis, Diabetes mellitus, Infections.
Díaz Ferrer
Javier
J
Unidad de Hígado, Hospital Nacional Edgardo Rebagliati, EsSALUD, Lima-Perú.
Román
Rossana
R
Ulloa
Viviana
V
Monge
Eduardo
E
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D007239:Infections / Q000453:epidemiology / Q000209:etiology*; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors