Haemolytic uraemic syndrome associated with gemcitabine.
Haemolytic uraemic syndrome (HUS) is a rare thromboembolic complication observed in patients with cancer. It is characterised by the clinical triad of acute renal failure, microangiopathic haemolytic anaemia and thrombocytopaenia. It may be associated with a variety of aetiologies, including chemotherapeutic agents such as mitomycin, cisplatin, bleomycin, 5-fluorouracil and, most recently, gemcitabine. We report a 70-year-old patient treated with gemcitabine who developed haemolytic uraemic syndrome.
Moya-Horno
Irene
I
Medical Oncology Service, Hospital de Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain.
Querol Niñerola
Rosa
R
Bonfill Abella
Teresa
T
Dalmau Pórtulas
Elsa
E
Gallardo-Díaz
Enrique
E
Saigí Grau
Eugeni
E
Pericay Pijaume
Carles
C
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D002277:Carcinoma / Q000188:drug therapy / Q000473:pathology; D003841:Deoxycytidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology; D019459:Urothelium / Q000187:drug effects / Q000473:pathology; D000093542:Gemcitabine
D003841:Deoxycytidine; D016190:Carboplatin; D000093542:Gemcitabine
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