[Surgical treatment of isolated right-sided infective endocarditis].
OBJECTIVE
To analyze the surgical treatment and outcomes of isolated right-sided infective endocarditis.


METHODS
From January 1994 to February 2009, 28 patients with isolated right-sided infective endocarditis underwent operation whose clinical data was retrospectively reviewed. There were 18 male and 10 female, age ranged from 10 to 72 years with a mean of 38 years. All of the patients presented intermittent fever, 14 patients presented heart failure (NYHA class III or IV), 25 patients had a history of pulmonary embolism or pneumonia, 18 patients had positive culture; 27 patients had intra-cardiac vegetations confirmed by echocardiogram. All the operations were performed under cardiopulmonary bypass. Antibiotic therapy continued for another 2 to 3 weeks after surgery.


RESULTS
One patient had underwent re-operation due to mediastinal bleeding, 2 patients needed mechanical ventilation for more than 1 week after surgery, renal dysfunction occurred in 3 patients. After surgery, 11 patients presented with mild or moderate tricuspid regurgitation before discharge. One patient (3.6%) died in hospital after surgery due to severe infection and multi-organ failure, the other 27 patients were cured and discharged. Patients were followed up for 6 months to 15 years.NYHA class decreased in all patients, and the symptoms of heart failure improved significantly after surgery. No recurrent case was found.


CONCLUSIONS
Surgery is an effective treatment for isolated right-sided infective endocarditis with congenital heart disease or right heart implants. Good outcomes are observed in these settings.
Zhang
Lin
L
Department of Cardiovascular Surgery, Chinese People's Liberation Army General Hospital, People's Liberation Army Institute of Cardiac Surgery, Beijing 100853, China.
Gao
Chang-qing
CQ
Jiang
Sheng-li
SL
Ren
Chong-lei
CL
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004697:Endocarditis, Bacterial / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult