Function follows form: defining mammary stem cells.
A new functional approach to identify and characterize normal mammary stem cells provides insights into the inner workings and molecular features of both these adult stem cells and their cancerous relatives. These findings further support the cancer stem cell hypothesis as well as the notion that a combination of traditional therapies with new approaches to specifically target cancer stem cells is needed if we are to win the battle against breast cancer.
Vivanco
María dM
Md
CIC bioGUNE, Cell Biology and Stem Cells Unit, Ed 801A, 48160 Derio (Bizkaia), Spain. mdmvivanco@cicbiogune.es
D053687:Adult Stem Cells / Q000166:cytology* / Q000378:metabolism; D000818:Animals; D001940:Breast / Q000166:cytology* / Q000378:metabolism; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D008321:Mammary Glands, Animal / Q000166:cytology / Q000378:metabolism; D051379:Mice; D008954:Models, Biological; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology