title: Endovascular thrombolysis for severe cerebral sinus thrombosis.
abstract: Cerebral venous and sinus thrombosis (CVST) is a rare but life-threatening disease accounting for less than 1% of all strokes and a poor outcome in around 10% of all patients. Early diagnosis is crucial because anticoagulation may reduce the risk of a fatal outcome and severe disability. However, the absence of specific features and the possibility of presentation without associated neurological signs can make its early recognition difficult. For these CVST patients with deteriorating symptoms, endovascular thrombolysis might give better outcome. We describe our five cases of CVST with clinical deteriorating symptoms treated with endovascular thrombolysis. Four patients made an excellent recovery, whereas one patient died despite maximal treatment including decompressive craniectomy.
authors.affiliation: The first Hospital of Changzhou City, Suzhou University, Changzhou City, China - wilson-pengya@hotmail.com.
authors.forename: Y
authors.initials: Y
authors.lastname: Peng
authors.forename: J-G
authors.initials: JG
authors.lastname: Xuan
authors.forename: Y-L
authors.initials: YL
authors.lastname: Yang
authors.forename: S-N
authors.initials: SN
authors.lastname: Wang
references.citation: AJNR Am J Neuroradiol. 1999 Mar;20(3):414-7
references.pmid: 10219406
references.citation: J Neurosurg. 2009 Mar;110(3):442-5
references.pmid: 18834264
references.citation: Ann Neurol. 1995 Jul;38(1):58-67
references.pmid: 7611726
references.citation: Clin Neurol Neurosurg. 2005 Feb;107(2):99-107
references.pmid: 15708223
references.citation: Neurol Sci. 2004 Oct;25 Suppl 3:S206-10
references.pmid: 15549538
references.citation: Stroke. 2001 Oct;32(10):2310-7
references.pmid: 11588319
references.citation: Lancet Neurol. 2007 Feb;6(2):162-70
references.pmid: 17239803
references.citation: Intern Med J. 2001 Sep-Oct;31(7):384-90
references.pmid: 11584899
references.citation: Cochrane Database Syst Rev. 2002;(4):CD002005
references.pmid: 12519565
references.citation: Stroke. 2008 May;39(5):1487-90
references.pmid: 18340091
references.citation: AJNR Am J Neuroradiol. 1999 Apr;20(4):568-70
references.pmid: 10319961
references.citation: Stroke. 1999 Mar;30(3):489-94
references.pmid: 10066841
references.citation: J Neurosurg. 1988 Feb;68(2):284-7
references.pmid: 3339445
references.citation: AJNR Am J Neuroradiol. 1997 Apr;18(4):639-45
references.pmid: 9127024
references.citation: Stroke. 2004 Mar;35(3):664-70
references.pmid: 14976332
references.citation: Eur J Neurol. 1994 Nov;1(2):109-26
references.pmid: 24283479
references.citation: AJR Am J Roentgenol. 1994 May;162(5):1191-8
references.pmid: 8166009
references.citation: Clin Radiol. 2002 Jun;57(6):449-61
references.pmid: 12069459
references.citation: Stroke. 2005 Aug;36(8):1720-5
references.pmid: 16002765
references.citation: Lancet. 1991 Sep 7;338(8767):597-600
references.pmid: 1679154