Silica gel-mediated rearrangement of allylic acetates. Application to the synthesis of 1,3-enynes.
Silica gel was found to efficiently promote the rearrangement of allylic acetates into their most stable regioisomers under microwave irradiation. The reaction is easy to perform and eco-friendly. This method was applied to the metal-free synthesis of 1,3-enynes.
Serra-Muns
Anna
A
Laboratoire de Chimie Organique, ESPCI ParisTech, UMR CNRS 7084, 10, rue Vauquelin, 75231 Paris Cedex 05, France.
Guérinot
Amandine
A
Reymond
Sébastien
S
Cossy
Janine
J