The prevention of rh-immunization.
Administration of Rh immune globulin to the Rh-negative unimmunized woman at risk of Rh-immunization is highly effective if given in sufficient dose prior to active Rh-immunization. Remaining problems are: 1. treating all of those at risk, 2. protecting those who abort, 3. treating after amniocentesis, 4. instituting an antenatal prophylaxis program to protect the 1.8 percent immunized too early to be protected by post-delivery injection of Rh immune globulin, 5. protecting those who have had massive transplacental fetal hemorrhages. All physicians practicing obstetrics should ensure that all of their unimmunized Rh-negative women are protected against Rh-immunization.
Bowman
J M
JM
Klin Wochenschr. 1957 Jun 15;35(12):637-8
13450287
Can Med Assoc J. 1967 Nov 18;97(21):1245-57
4168032
Br Med J. 1961 May 27;1(5238):1486-90
13699661
Transfusion. 1971 Nov-Dec;11(6):333-9
5002765
Lancet. 1954 Jun 12;266(6824):1213-5
13164357
Pediatr Res. 1976 Apr;10(4):213-5
818607
Presse Med. 1970 Nov 7;78(47):2072
4098405
Immunology. 1975 Feb;28(2):349-57
804437
Vox Sang. 1973 Oct;25(4):308-16
4201742
Am J Obstet Gynecol. 1968 Feb 15;100(4):567-9
4965940
Science. 1946 May 10;103(2680):583-4
17779885
Transfusion. 1964 Jan-Feb;4:26-32
14105934