Rapid anti-pathogen response in ant societies relies on high genetic diversity.
Social organisms are constantly exposed to infectious agents via physical contact with conspecifics. While previous work has shown that disease susceptibility at the individual and group level is influenced by genetic diversity within and between group members, it remains poorly understood how group-level resistance to pathogens relates directly to individual physiology, defence behaviour and social interactions. We investigated the effects of high versus low genetic diversity on both the individual and collective disease defences in the ant Cardiocondyla obscurior. We compared the antiseptic behaviours (grooming and hygienic behaviour) of workers from genetically homogeneous and diverse colonies after exposure of their brood to the entomopathogenic fungus Metarhizium anisopliae. While workers from diverse colonies performed intensive allogrooming and quickly removed larvae covered with live fungal spores from the nest, workers from homogeneous colonies only removed sick larvae late after infection. This difference was not caused by a reduced repertoire of antiseptic behaviours or a generally decreased brood care activity in ants from homogeneous colonies. Our data instead suggest that reduced genetic diversity compromises the ability of Cardiocondyla colonies to quickly detect or react to the presence of pathogenic fungal spores before an infection is established, thereby affecting the dynamics of social immunity in the colony.
Ugelvig
Line V
LV
Evolution, Behaviour and Genetics, Biology I, University of Regensburg, Universitätsstrasse 31, , 93040 Regensburg, Germany.
Kronauer
Daniel J C
DJ
Schrempf
Alexandra
A
Heinze
Jürgen
J
Cremer
Sylvia
S
D000818:Animals; D001000:Ants / Q000235:genetics / Q000276:immunology* / Q000382:microbiology*; D001522:Behavior, Animal; D014644:Genetic Variation; D054884:Host-Pathogen Interactions; D006920:Hygiene; D007113:Immunity, Innate; D052981:Metarhizium / Q000502:physiology*; D012919:Social Behavior
J Comp Physiol A. 2001 Jul;187(6):441-52
11548991
Exp Appl Acarol. 2005;37(3-4):231-44
16323053
Proc Biol Sci. 2007 Jan 7;274(1606):67-72
17015336
J Insect Physiol. 2009 Sep;55(9):774-80
19442668
Naturwissenschaften. 2003 Jun;90(6):265-8
12835837
Proc Biol Sci. 2006 Apr 7;273(1588):797-804
16618672
Am Nat. 1998 Apr;151(4):392-6
18811329
Science. 2007 Jul 20;317(5836):362-4
17641199
Ecol Lett. 2008 Jul;11(7):682-9
18371089
Evolution. 2004 Jun;58(6):1251-60
15266974
J Invertebr Pathol. 1999 Jan;73(1):25-33
9878286
Curr Biol. 2003 Feb 4;13(3):219-23
12573217
Malar J. 2005 Jan 11;4:3
15644136
J Neurobiol. 2003 Jun;55(3):341-54
12717703
Evolution. 2001 Jun;55(6):1136-45
11475049
Naturwissenschaften. 2002 Dec;89(12):565-8
12536279
Trends Ecol Evol. 1988 Oct;3(10):254-9
21227241
Annu Rev Entomol. 2001;46:413-40
11112175
Heredity (Edinb). 2006 Jul;97(1):75-80
16705320
Curr Biol. 2007 Aug 21;17(16):R693-702
17714663
Proc Biol Sci. 2003 Jan 7;270(1510):99-103
12596763
Proc Biol Sci. 2001 May 22;268(1471):1033-9
11375087
Evolution. 2003 Apr;57(4):777-83
12778547
Annu Rev Entomol. 2009;54:405-23
18793100
J Chem Ecol. 2009 Sep;35(9):1108-16
19816752
Proc Biol Sci. 2002 Sep 7;269(1502):1811-9
12350269
Naturwissenschaften. 2006 Apr;93(4):195-9
16518641
Curr Biol. 2007 Nov 20;17(22):1967-71
17980590
J Evol Biol. 2007 Jan;20(1):79-86
17210002
Proc Natl Acad Sci U S A. 2002 May 14;99(10):6838-42
12011442
Mol Ecol. 2010 Apr;19(7):1452-61
20298472
Proc Biol Sci. 2006 Oct 22;273(1601):2633-40
17002949
Proc Biol Sci. 2010 Feb 22;277(1681):609-15
19864289
J Econ Entomol. 2001 Apr;94(2):326-31
11332821
Evolution. 2001 Aug;55(8):1639-43
11580023