Association between the catechol-O-methyltransferase Val158Met polymorphism and panic disorder: a replication.
The association between the catechol-O-methyltransferase Val158Met polymorphism and panic disorder was studied in a Swedish sample of 211 patients and 452 controls. We found a significant excess of the Val allele in both male and female patients, the latter but not the former finding being in line with previous studies.
Annerbrink
Kristina
K
Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. kristina.annerbrink@pharm.gu.se
Westberg
Lars
L
Olsson
Marie
M
Allgulander
Christer
C
Andersch
Sven
S
Sjödin
Ingemar
I
Holm
Göran
G
Eriksson
Elias
E
D000328:Adult; D002394:Catechol O-Methyltransferase / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D056726:Genetic Association Studies; D006801:Humans; D008297:Male; D008715:Methionine / Q000235:genetics*; D008875:Middle Aged; D016584:Panic Disorder / Q000235:genetics*; D011110:Polymorphism, Genetic; D013548:Sweden; D014633:Valine / Q000235:genetics*
D008715:Methionine; D002394:Catechol O-Methyltransferase; D014633:Valine