Programmed assembly of organic radicals on DNA.
Nitronyl nitroxide radical introduced to naphthyridine carbamate dimer is noncovalently bound to a CGG/CGG triad as an addressable position in DNA duplexes, leading to the programmed assembly of the radical molecules into an 11-mer duplex and a tandem repetitive array of double stranded DNA.
Maekawa
Kensuke
K
Department of Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Ibaraki 567-0047, Japan.
Nakazawa
Shigeaki
S
Atsumi
Hiroshi
H
Shiomi
Daisuke
D
Sato
Kazunobu
K
Kitagawa
Masahiro
M
Takui
Takeji
T
Nakatani
Kazuhiko
K
D002219:Carbamates / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D009287:Naphthyridines / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D018911:Trinucleotide Repeats
D002219:Carbamates; D009287:Naphthyridines; D009589:Nitrogen Oxides; D004247:DNA; C039900:nitroxyl