Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells.
A novel dextran-based nanoprobe was synthesized and demonstrated the pH-activated near-infrared (NIR) fluorescence in the physiologically acidic aqueous solutions and acidic compartments in human glioblastoma cancer cells.
Li
Cong
C
School of Pharmacy, Fudan University, Shanghai 201203, China. congli@fudan.edu.cn
Li
Kai
K
Yan
Huihui
H
Li
Guanghui
G
Xia
Jinsong
J
Wei
Xunbin
X
D045744:Cell Line, Tumor; D002470:Cell Survival; D003911:Dextrans / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
D003911:Dextrans; D005456:Fluorescent Dyes