title: [Cheek paresthesia by an osteosarcoma].
abstract: A 21-year-old woman was referred by the dental practitioner to an oral surgeon concerning a hard elastic swelling of the left cheek in combination with local paresthesia. Histopathologic and radiographic examination revealed an osteosarcoma in the left segment of the maxilla. Subsequently, the patient was referred to a medical centre for head and neck oncology. The treatment consisted of 3 courses neoadjuvant chemotherapy, followed by radical surgical resection of the tumor, and 3 courses adjuvant chemotherapy. One year after treatment, there was no sign of local tumor recurrence or metastases. An osteosarcoma is a malignant tumor of bone forming cells. About 10% of osteosarcomas are appearing in the head and neck region, primarily in the mandible and the maxilla. The treatment of choice is adequate surgical removal. Treatment with (neo)adjuvant chemotherapy seems to have additional benefit, but this needs further research.
authors.affiliation: Centrum voor Tandheelkunde en Mondzorgkunde, Universitair Medisch Centrum Groningen, Groningen. s.veldhuis@kchir.umcg.nl
authors.forename: S K B
authors.initials: SK
authors.lastname: Veldhuis
authors.forename: M J H
authors.initials: MJ
authors.lastname: Witjes
authors.forename: H
authors.initials: H
authors.lastname: Reintsema
authors.forename: J L N
authors.initials: JL
authors.lastname: Roodenburg
authors.forename: K P
authors.initials: KP
authors.lastname: Schepman
authors.forename: N M
authors.initials: NM
authors.lastname: Timmenga
authors.forename: P S
authors.initials: PS
authors.lastname: van der Hem
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008441:Maxillary Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D012516:Osteosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult