title: Four new ent-kaurane diterpenoids from the fruits of Annona cherimola.
abstract: Four new ent-kaurane diterpenoids (16R)-ent-kauran-17,19-diol (1), (16R)-17-hydroxy-ent-kauran-19-oic acid (2), (16S)-17-hydroxy-ent-kauran-19-oic acid (3), and (16R)-17-dimethoxy-ent-kauran-19-oic acid (4) have been isolated from the fresh fruits of Annona cherimola together with eight known compounds. Their structures are determined on the basis of spectroscopic data and optical rotation.
authors.affiliation: Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 862-0082, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Miyashita
authors.forename: Makiko
authors.initials: M
authors.lastname: Nishida
authors.forename: Masafumi
authors.initials: M
authors.lastname: Okawa
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nohara
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yoshimitsu
mesh_terms: D031041:Annona / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry*; D045786:Diterpenes, Kaurane / Q000737:chemistry* / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D045786:Diterpenes, Kaurane; D010936:Plant Extracts