title: Remarkable effect of phosphine on the reactivity of O,P-acetal--efficient substitution reaction of O,P-acetal.
abstract: The structure and electronic nature of the phosphine have a significant influence on not only the formation, but also the subsequent transformation of O,P-acetals. The O,P-acetals generated from tris(o-tolyl)phosphine [(o-tol)(3)P] underwent efficient substitution reactions with various nucleophiles.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan. fujioka@phs.osaka-u.ac.jp
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Fujioka
authors.forename: Akihiro
authors.initials: A
authors.lastname: Goto
authors.forename: Kazuki
authors.initials: K
authors.lastname: Otake
authors.forename: Ozora
authors.initials: O
authors.lastname: Kubo
authors.forename: Kenzo
authors.initials: K
authors.lastname: Yahata
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Sawama
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Maegawa
mesh_terms: D000080:Acetals / Q000737:chemistry*; D006868:Hydrolysis; D010720:Phosphines / Q000737:chemistry*
chemical_list: D000080:Acetals; D010720:Phosphines; C044646:phosphine