Larvicidal activity of 94 extracts from ten plant species of northeastern of Brazil against Aedes aegypti L. (Diptera: Culicidae).
In an effort to find effective and affordable ways to control of Aedes aegypti L. (Diptera: Culicidae), the larvicidal activities of 94 extracts from ten plant species belonging to eight families [Guettarda grazielae and Spermacoce verticillata (Rubiaceae), Coccoloba mollis and Triplaris americana (Polygonaceae), Eschweilera ovata (Lecytidaceae), Merremia aegyptia (Convolvulaceae), Ouratea nitida (Ochnnaceae), Protium heptaphyllum (Burseraceae), Rourea doniana (Connaraceae), and Tovomita brevistaminea (Guttiferae)], widely found in the northeast of Brazil, were initially screened at 250 microg/mL. Nineteen of the 94 extracts from six plant species (C. mollis, G. grazielae, M. aegyptia, R. doniana, S. verticillata, and T. americana) showed significant activity (>75% mortality) against the fourth instar larvae. Some of these extracts showed 100% mosquito larvae mortality, with LD(50) values lower 200 microg/mL. When compared to synthetic insecticide Temephos (LD(50) 8.7 microg/mL), two of them, hexane (LD(50) 12.1 microg/mL) and ethyl acetate (LD(50) 51.6 microg/mL) extracts from stems of R. doniana and G. grazielae, respectively, were the most effective. The isolation and purification of these extracts are in progress and evaluation of these compounds will be needed to identify the active component.
Oliveira
Patrícia V
PV
Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, 57072-970, Maceió, Alagoas, Brazil.
Ferreira
Jesú C
JC
Moura
Fabyanne S
FS
Lima
Gerson S
GS
de Oliveira
Fernando M
FM
Oliveira
Patrícia Emanuella S
PE
Conserva
Lucia M
LM
Giulietti
Ana Maria
AM
Lemos
Rosangela P Lyra
RP
D000330:Aedes / Q000187:drug effects*; D000818:Animals; D001938:Brazil; D007306:Insecticides / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010944:Plants / Q000737:chemistry*; D016019:Survival Analysis; D000002:Temefos / Q000494:pharmacology
D007306:Insecticides; D010936:Plant Extracts; D000002:Temefos
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