New N-acyl taurine from the sea urchin Glyptocidaris crenularis.
A new N-acyl taurine (1), together with a new natural product, l-(beta-D-ribofuranosyl)-1,2,4-triazole (4), and two known compounds (2 and 3), were isolated from the sea urchin, Glyptocidaris crenularis. The new N-acyl taurine was elucidated as 2-(5R,15S-dihydroxyeicosanoylamino) ethanesulfonic acid on the basis of spectroscopic (NMR, MS) analyses and the modified Mosher ester method. Compound 2 showed significant toxicity against brine shrimp larvae.
Zhou
Xuefeng
X
Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.
Xu
Tunhai
T
Wen
Kewei
K
Yang
Xian-Wen
XW
Xu
Shi-Hai
SH
Liu
Yonghong
Y
D000818:Animals; D006893:Hydroxyeicosatetraenoic Acids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012617:Sea Urchins / Q000737:chemistry*; D013654:Taurine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification
C551885:2-(5,15-dihydroxyeicosanoylamino)ethanesulfonic acid; D006893:Hydroxyeicosatetraenoic Acids; D013654:Taurine