Design of fluorescently tagged poly(alkyl cyanoacrylate) nanoparticles for human brain endothelial cell imaging.
Rhodamine B-tagged poly(alkyl cyanoacrylate) amphiphilic copolymers have been synthesised, characterised and successfully used to prepare fluorescent nanoparticles for human brain endothelial cell imaging, allowing their uptake and intracellular trafficking to be finely observed.
Brambilla
Davide
D
Laboratoire de Physico-Chimie, Pharmacotechnie et Biopharmacie, Université Paris-Sud, UMR CNRS 8612, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Nicolas
Julien
J
Le Droumaguet
Benjamin
B
Andrieux
Karine
K
Marsaud
Véronique
V
Couraud
Pierre-Olivier
PO
Couvreur
Patrick
P
D001921:Brain / Q000166:cytology; D002460:Cell Line; D003487:Cyanoacrylates / Q000737:chemistry*; D042783:Endothelial Cells / Q000166:cytology*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D018613:Microscopy, Confocal; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry
D003487:Cyanoacrylates; D005456:Fluorescent Dyes; D011108:Polymers; D012235:Rhodamines; C029773:rhodamine B