title: Knitting complex weaves with DNA origami.
abstract: The past three decades have witnessed steady growth in our ability to harness DNA branched junctions as building blocks for programmable self-assembly of diverse supramolecular architectures. The DNA-origami method, which exploits the availability of long DNA sequences to template sophisticated nanostructures, has played a major role in extending this trend through the past few years. Today, two-dimensional and three-dimensional custom-shaped nanostructures comparable in mass to a small virus can be designed, assembled, and characterized with a prototyping cycle on the order of a couple of weeks.
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. William_Shih@dfci.harvard.edu
authors.forename: William M
authors.initials: WM
authors.lastname: Shih
authors.forename: Chenxiang
authors.initials: C
authors.lastname: Lin
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000096:biosynthesis / Q000737:chemistry* / Q000235:genetics; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*
chemical_list: D004247:DNA
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