[Allopurinol-induced hypersensitivity syndrome resulting in death].
The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.
Laurisch
Sören
S
Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Hannover, Germany. Laurisch.Soeren@mh-hannover.de
Jaedtke
Maren
M
Demir
Reyhan
R
Sorrentino
Sajoscha A
SA
Kielstein
Jan T
JT
Rennekampff
Hans-Oliver
HO
Vogt
Peter M
PM
Meyer
Gerd P
GP
Fuchs
Martin
M
Klein
Gunnar
G
Drexler
Hartmut
H
Schieffer
Bernhard
B
Napp
L Christian
LC
D000368:Aged; D000493:Allopurinol / Q000633:toxicity*; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D017809:Fatal Outcome; D006073:Gout / Q000188:drug therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D012008:Recurrence; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
D000493:Allopurinol
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