title: Characterization of breast tissue using energy-dispersive X-ray diffraction computed tomography.
abstract: A method for sample characterization using energy-dispersive X-ray diffraction computed tomography (EDXRDCT) is presented. The procedures for extracting diffraction patterns from the data and the corrections applied are discussed. The procedures were applied to the characterization of breast tissue samples, 6mm in diameter. Comparison with histological sections of the samples confirmed the possibility of grouping the patterns into five families, corresponding to adipose tissue, fibrosis, poorly differentiated cancer, well differentiated cancer and benign tumour.
authors.affiliation: Department of Medical Physics and Bioengineering, University College London, UK. s.pani@surrey.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Pani
authors.forename: E J
authors.initials: EJ
authors.lastname: Cook
authors.forename: J A
authors.initials: JA
authors.lastname: Horrocks
authors.forename: J L
authors.initials: JL
authors.lastname: Jones
authors.forename: R D
authors.initials: RD
authors.lastname: Speller
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D001706:Biopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000145:classification* / Q000473:pathology*; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014961:X-Ray Diffraction / Q000379:methods*