Ag-containing all-carbon 1,3-dipoles: generation and formal cycloaddition for furo[3,2-b]-beta/gamma-lactams.
A new strategy for highly diastereoselective synthesis of furo[3,2-b]-beta-lactams and furo[3,2-b]-gamma-lactams via a novel Ag(I)-mediated intramolecular 1,3-dipolar cycloaddition of oxo-N-propargylamides, is developed and the possible mechanism of these transformation is proposed.
Zhang
Zhiguo
Z
Department of Chemistry, Northeast Normal University, Changchun, 130024, PR China.
Zhang
Qian
Q
Ni
Zhikun
Z
Liu
Qun
Q