Eosinophilia and eosinophilic infiltration into splenic B-cell high-grade lymphoma in a dog.
A 13-year-old mixed-breed dog showing ascites, anorexia and anemia was found to have leukocytosis with marked eosinophilia, splenomegaly and hepatomegaly. The dog died 4 days after initial presentation and was diagnosed with splenic high-grade B-cell lymphoma at necropsy. Remarkable infiltrations of eosinophils were observed in spleen and liver tissues. The eosinophilia and infiltration of eosinophils into the lesions could have been associated with B-cell lymphoma because causes other than lymphoma were excluded. This is the first report of eosinophilia and eosinophilic infiltrations into neoplastic lesions in a dog with high-grade B-cell lymphoma.
Tomiyasu
Hirotaka
H
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
Fujino
Yasuhito
Y
Ugai
Jun
J
Goto-Koshino
Yuko
Y
Ide
Tetsuya
T
Takahashi
Masashi
M
Ohno
Koichi
K
Uchida
Kazuyuki
K
Nakayam
Hiroyuki
H
Tsujimoto
Hajime
H
D000740:Anemia / Q000209:etiology / Q000662:veterinary; D000818:Animals; D000855:Anorexia / Q000209:etiology / Q000662:veterinary; D001201:Ascites / Q000209:etiology / Q000662:veterinary; D001774:Blood Chemical Analysis / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004802:Eosinophilia / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D004804:Eosinophils / Q000473:pathology; D005260:Female; D016393:Lymphoma, B-Cell / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D010052:Ovariectomy / Q000662:veterinary; D011859:Radiography