title: Detection of low-populated reaction intermediates with hyperpolarized NMR.
abstract: Hyperpolarized (13)C NMR spectroscopy can provide the sensitivity and spectral resolution to detect, identify and quantify low-populated reaction intermediates, thus yielding direct chemical information on reaction mechanisms in real-time assays.
authors.affiliation: Albeda Research, Gamle Carlsberg Vej 10, 2500 Valby, Denmark.
authors.forename: Pernille R
authors.initials: PR
authors.lastname: Jensen
authors.forename: Sebastian
authors.initials: S
authors.lastname: Meier
authors.forename: Jan H
authors.initials: JH
authors.lastname: Ardenkjaer-Larsen
authors.forename: Jens Ø
authors.initials: JØ
authors.lastname: Duus
authors.forename: Magnus
authors.initials: M
authors.lastname: Karlsson
authors.forename: Mathilde H
authors.initials: MH
authors.lastname: Lerche
mesh_terms: D000106:Acetate-CoA Ligase / Q000737:chemistry* / Q000378:metabolism; D000085:Acetates / Q000737:chemistry*; D002247:Carbon Isotopes; D002384:Catalysis; D004789:Enzyme Activation; D019811:Hydroxylamine / Q000737:chemistry*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D000085:Acetates; D002247:Carbon Isotopes; D019811:Hydroxylamine; D000106:Acetate-CoA Ligase