title: Transcatheter repair of perivalvular regurgitation.
abstract: Hemodynamically significant perivalvular regurgitation affects about 1.5% of all prosthetic valve implants. Reoperation carries increased risk--especially in the setting of concomitant comorbidities of left ventricular dysfunction, prior coronary artery bypass grafts, renal dysfunction, and advanced age. Transcatheter closure of the perivalvular regurgitant channel using a variety of occluders has been available for several years; however, recent improvements in technology and technique have made this therapy more effective and available to a wider group of patients. This article describes the recent advances and the state of the art of this therapy.
authors.affiliation: Division of Pediatric Cardiology, Mount Sinai School of Medicine, New York, NY 10029, USA. barry.love@mssm.edu
authors.forename: Barry A
authors.initials: BA
authors.lastname: Love
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Fischer
authors.forename: Alexander
authors.initials: A
authors.lastname: Mittnacht
authors.forename: Jill
authors.initials: J
authors.lastname: Kalman
authors.forename: David H
authors.initials: DH
authors.lastname: Adams
mesh_terms: D006328:Cardiac Catheterization / Q000379:methods*; D017548:Echocardiography, Transesophageal / Q000379:methods; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D011475:Prosthesis Failure; D012086:Reoperation; D012307:Risk Factors; D016896:Treatment Outcome