title: [Diagnosis and therapy in multiple sclerosis].
abstract: Multiple sclerosis (MS) is an inflammatory disease the central nervous system. Its first manifestation and clinical course of the disease is highly heterogeneous. The diagnosis is based on the verification of neurological deficits, the development of the clinical course and the magnetic resonance imaging (MRI) of the head and spine. The therapy comprises disease modifying drugs (DMD), therapy for acute relapses and escalation therapy according the German MS-Therapy-Consensus-Group (MSTKG). An early therapy initiation and a systematic therapy of acute relapses and symptoms determine the modern MS-management.
authors.affiliation: MS Ambulanz & Restaurative Neurologie, Neurologische Universitätsklinik, Otto-von-Guericke Universität Magdeburg. michael.sailer@med.ovgu.de
authors.forename: Michael
authors.initials: M
authors.lastname: Sailer
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002490:Central Nervous System / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D005858:Germany / Q000453:epidemiology; D000068717:Glatiramer Acetate; D005938:Glucocorticoids / Q000378:metabolism; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D008942:Mitoxantrone / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy; D010455:Peptides / Q000627:therapeutic use; D010956:Plasmapheresis; D011859:Radiography
chemical_list: D000700:Analgesics; D000998:Antiviral Agents; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D010455:Peptides; D000068717:Glatiramer Acetate; D016899:Interferon-beta; D008942:Mitoxantrone