Wild bird's-eye view of influenza virus A(H1N1) phylogenetic evolution.
Wild bird fecal samples collected and characterized by the USDA as part of a national surveillance effort were sequenced to study the genetic relatedness of avian, swine, and human H1 and N1 subtypes. Our results find that the 2009 H1N1 human outbreak is closely related to swine virus, but falls into different clades in the H1 and N1 trees. Further, there is evidence of multiple viral genetic exchanges between birds and swine. Ongoing research across host species contributes to an understanding of the circulation of influenza viruses.
Piaggio
Antoinette J
AJ
National Wildlife Research Center, United States Department of Agriculture, Wildlife Services, 4101 LaPorte Avenue, Fort Collins, CO 80521, USA. Toni.J.Piaggio@aphis.usda.gov
Clark
Larry
L
Franklin
Alan B
AB
Kolokotronis
Sergios-Orestis
SO
D000818:Animals; D001717:Birds; D019143:Evolution, Molecular; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification / Q000235:genetics*; D005585:Influenza in Birds / Q000821:virology*; D007251:Influenza, Human / Q000821:virology; D009976:Orthomyxoviridae Infections / Q000821:virology; D010802:Phylogeny; D013553:Swine Diseases / Q000821:virology; D014481:United States; D016885:United States Department of Agriculture; D015047:Zoonoses
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