title: Human papillomavirus in the etiology of head and neck carcinomas.
abstract: BACKGROUND
  For more than 20 years, infection with the human papillomavirus (HPV) has been of a matter of interest not only to gynecologists but also to maxillofacial surgeons and othorhinolaryngologists. HPV is generally known to be involved in cervical cancer. Recently, there are many clinical studies pointed out the potentially dangerous connection between HPV infection and head and neck carcinomas (HNC). HPV infection was identified as a possible etiological factor in 15-30% of HNC.
  
  
  METHODS
  Aim of this article is to summarize the recent knowledge about the HPV infection with regards to etiology of head and neck cancer.
  
  
  RESULTS
  It has been proven that HPV infection is related to development of head and neck cancer and that the sexual behavior has played an important role in the viral transmission. HNC of viral etiology have been observed mostly in younger people; their curability is difficult and prognosis serious.
  
  
  CONCLUSIONS
  Beside the well known correlation between developing of new head and neck cancer and bad habits (smoking, alcohol abuse, poor oral hygiene etc.) we should take into consideration the sexual promiscuity and alternative sexual practices. Vaccination against cervical cancer, recommended to young women, should be extended to their male partners to prevent the virus transmission and decrease the HNC incidence.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Hospital Olomouc, I. P. Pavlova 6, Olomouc 77900, Czech Republic. Michl.Petr@seznam.cz
authors.forename: Petr
authors.initials: P
authors.lastname: Michl
authors.forename: Jindrich
authors.initials: J
authors.lastname: Pazdera
authors.forename: Martin
authors.initials: M
authors.lastname: Prochazka
authors.forename: Richard
authors.initials: R
authors.lastname: Pink
authors.forename: Tatana
authors.initials: T
authors.lastname: Stosova
mesh_terms: D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000821:virology*; D006801:Humans; D030361:Papillomavirus Infections / Q000150:complications* / Q000175:diagnosis