title: Minimally invasive and computer-navigated total hip arthroplasty: a qualitative and systematic review of the literature.
abstract: BACKGROUND
  Both minimally invasive surgery (MIS) and computer-assisted surgery (CAS) for total hip arthroplasty (THA) have gained popularity in recent years. We conducted a qualitative and systematic review to assess the effectiveness of MIS, CAS and computer-assisted MIS for THA.
  
  
  METHODS
  An extensive computerised literature search of PubMed, Medline, Embase and OVIDSP was conducted. Both randomised clinical trials and controlled clinical trials on the effectiveness of MIS, CAS and computer-assisted MIS for THA were included. Methodological quality was independently assessed by two reviewers. Effect estimates were calculated and a best-evidence synthesis was performed.
  
  
  RESULTS
  Four high-quality and 14 medium-quality studies with MIS THA as study contrast, and three high-quality and four medium-quality studies with CAS THA as study contrast were included. No studies with computer-assisted MIS for THA as study contrast were identified. Strong evidence was found for a decrease in operative time and intraoperative blood loss for MIS THA, with no difference in complication rates and risk for acetabular outliers. Strong evidence exists that there is no difference in physical functioning, measured either by questionnaires or by gait analysis. Moderate evidence was found for a shorter length of hospital stay after MIS THA. Conflicting evidence was found for a positive effect of MIS THA on pain in the early postoperative period, but that effect diminished after three months postoperatively. Strong evidence was found for an increase in operative time for CAS THA, and limited evidence was found for a decrease in intraoperative blood loss. Furthermore, strong evidence was found for no difference in complication rates, as well as for a significantly lower risk for acetabular outliers.
  
  
  CONCLUSIONS
  The results indicate that MIS THA is a safe surgical procedure, without increases in operative time, blood loss, operative complication rates and component malposition rates. However, the beneficial effect of MIS THA on functional recovery has to be proven. The results also indicate that CAS THA, though resulting in an increase in operative time, may have a positive effect on operative blood loss and operative complication rates. More importantly, the use of CAS results in better positioning of acetabular component of the prosthesis.
authors.affiliation: Department of Orthopaedics, University Medical Center Groningen, University of Groningen, The Netherlands. i.reininga@orth.umcg.nl
authors.forename: Inge H F
authors.initials: IH
authors.lastname: Reininga
authors.forename: Wiebren
authors.initials: W
authors.lastname: Zijlstra
authors.forename: Robert
authors.initials: R
authors.lastname: Wagenmakers
authors.forename: Alexander L
authors.initials: AL
authors.lastname: Boerboom
authors.forename: Bregtje P
authors.initials: BP
authors.lastname: Huijbers
authors.forename: Johan W
authors.initials: JW
authors.lastname: Groothoff
authors.forename: Sjoerd K
authors.initials: SK
authors.lastname: Bulstra
authors.forename: Martin
authors.initials: M
authors.lastname: Stevens
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods* / Q000706:statistics & numerical data / Q000639:trends*; D006801:Humans; D007432:Intraoperative Period; D007902:Length of Stay; D019060:Minimally Invasive Surgical Procedures / Q000379:methods* / Q000706:statistics & numerical data / Q000639:trends*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D025321:Surgery, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data / Q000639:trends*; D013997:Time Factors; D016896:Treatment Outcome
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