title: Multilocus sequence types of carbapenem-resistant Pseudomonas aeruginosa in Singapore carrying metallo-beta-lactamase genes, including the novel bla(IMP-26) gene.
abstract: Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from an earlier study showed that the epidemic clones from 2000 have not become established.
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore. koh.tse.hsien@sgh.com.sg
authors.forename: Tse Hsien
authors.initials: TH
authors.lastname: Koh
authors.forename: Cheng Teng
authors.initials: CT
authors.lastname: Khoo
authors.forename: Thuan Tong
authors.initials: TT
authors.lastname: Tan
authors.forename: Mohamed Amir Bin Mohamed
authors.initials: MA
authors.lastname: Arshad
authors.forename: Li Ping
authors.initials: LP
authors.lastname: Ang
authors.forename: Lee Jin
authors.initials: LJ
authors.lastname: Lau
authors.forename: Li-Yang
authors.initials: LY
authors.lastname: Hsu
authors.forename: Eng Eong
authors.initials: EE
authors.lastname: Ooi
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D015780:Carbapenems / Q000494:pharmacology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics; D017422:Sequence Analysis, DNA / Q000379:methods; D012846:Singapore; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases
references.citation: J Clin Microbiol. 2004 Nov;42(11):5378-80
references.pmid: 15528748
references.citation: Environ Microbiol. 2002 Dec;4(12):898-911
references.pmid: 12534471
references.citation: Clin Microbiol Infect. 2001 Feb;7(2):88-91
references.pmid: 11298149
references.citation: Acta Microbiol Immunol Hung. 2008 Dec;55(4):447-54
references.pmid: 19130752
references.citation: J Clin Microbiol. 2004 Dec;42(12):5644-9
references.pmid: 15583294
references.citation: J Antimicrob Chemother. 2007 Feb;59(2):321-2
references.pmid: 17185300
references.citation: J Antimicrob Chemother. 2009 Jul;64(1):46-51
references.pmid: 19398456