Successful treatment of saphenous venous graft thrombus by tirofiban infusion.
A 60-year old man with a history of coronary-artery bypass grafting presented with symptoms of acute coronary syndrome. Coronary angiography revealed a huge intraluminal thrombus in the saphenous vein graft to the second obtuse marginal branch of the left circumflex artery. A glycoprotein IIb/IIIa inhibitor (tirofiban) was administered intravenously. Two days later, thrombus dissolution and Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow were evident on repeat coronary angiography. Glycoprotein IIb/IIIa inhibitors may be useful in a thrombus-laden saphenous-vein graft.
Sentürk
Tunay
T
Department of Cardiology, School of Medicine, Uludag University, Görükle, Bursa, Turkey. tunaysenturk@hotmail.com
Aydin Kaderli
Aysel
A
Aydin
Ozlem
O
Yeşilbursa
Dilek
D
Akin Serdar
Osman
O
D001026:Coronary Artery Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D012501:Saphenous Vein / Q000637:transplantation*; D013997:Time Factors; D000077466:Tirofiban; D014443:Tyrosine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000188:drug therapy*
D010975:Platelet Aggregation Inhibitors; D014443:Tyrosine; D000077466:Tirofiban