title: [Globus sensation : A clinical review].
abstract: Globus sensation is a medially felt lump in the throat. It can be associated with a number of different diseases, but this symptom may also occur monosymptomatically as a somatoform disorder or as a secondary somatoform illness behavior. Globus sensation may be persistent or intermittent. Diagnosis requires close interdisciplinary cooperation, since the globus may be a symptom of anxiety, depression or personality disorders. Firstly, patients should undergo a thorough otolaryngological examination (including careful medical history taking), possibly in cooperation with other medical specialists. Subsequent psychosomatic and clinical tests - if necessary - may be time-consuming due to complex interrelations between somatic vulnerability and psychosocial coping strategies. Sometimes a comorbid disorder is diagnosed and the primary disease treated; however, the identification of multiple etiologically effective mechanisms is impossible. If the patient is unable to accept his benign monosymptomatic globus as a somatoform disorder (ICD-10; F45.8), a combination of pharmacologic intervention and cognitive-behavioral intervention as an integrated treatment approach is recommended. However, the symptom has a strong tendency to recur. Since controlled therapy studies are scant to date, evidence-based treatment concepts are currently not available.
authors.affiliation: Universitätsmedizin Göttingen, Deutschland. ckiese@med.uni-goettingen.de
authors.forename: C
authors.initials: C
authors.lastname: Kiese-Himmel
mesh_terms: D000223:Adaptation, Psychological; D001008:Anxiety Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D015897:Comorbidity; D003291:Conversion Disorder / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy; D003299:Cooperative Behavior; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D055809:Illness Behavior; D033183:Interdisciplinary Communication; D008016:Life Change Events; D010554:Personality Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013001:Somatoform Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy
chemical_list: D011619:Psychotropic Drugs
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