Exopolysaccharide synthesized by Lactobacillus reuteri decreases the ability of enterotoxigenic Escherichia coli to bind to porcine erythrocytes.
This study investigated the therapeutic potential of bacterial polysaccharides by employing a model system based on enteroxigenic Escherichia coli (ETEC)-induced hemagglutination of erythrocytes. Exopolysaccharides produced by strains of Lactobacillus reuteri inhibited ETEC-induced hemagglutination of porcine erythrocytes. No effect was observed for dextran produced from Weissella cibaria and commercially available oligo- and polysaccharides.
Wang
Yvonne
Y
University of Alberta, Department of Agricultural, Food and Nutritional Science, Edmonton, AB T6G 2P5, Canada.
Gänzle
Michael G
MG
Schwab
Clarissa
C
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D000898:Antibiosis; D001422:Bacterial Adhesion; D054307:Enterotoxigenic Escherichia coli / Q000187:drug effects* / Q000472:pathogenicity; D004912:Erythrocytes / Q000382:microbiology*; D006384:Hemagglutination / Q000187:drug effects; D052200:Limosilactobacillus reuteri / Q000378:metabolism*; D056584:Leuconostocaceae / Q000378:metabolism; D011135:Polysaccharides, Bacterial / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D013552:Swine
D000900:Anti-Bacterial Agents; D011135:Polysaccharides, Bacterial
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