Adverse events in analgesic treatment with tramadol associated with CYP2D6 extensive-metaboliser and OPRM1 high-expression variants.
Kim
Eunjin
E
Choi
Chan-Bum
CB
Kang
Changwon
C
Bae
Sang-Cheol
SC
D000701:Analgesics, Opioid / Q000009:adverse effects*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D009325:Nausea / Q000139:chemically induced; D017450:Receptors, Opioid, mu / Q000235:genetics*; D014147:Tramadol / Q000009:adverse effects*; D014839:Vomiting / Q000139:chemically induced
D000701:Analgesics, Opioid; C485764:OPRM1 protein, human; D017450:Receptors, Opioid, mu; D014147:Tramadol; D019389:Cytochrome P-450 CYP2D6