title: [Feed-related selenium poisoning in swine].
abstract: The following case report describes a selenium toxicosis in a pig-fattening farm of two finisher groups. The diseased animals partly showed ataxia and paresis or intense lameness in connection with band-like ablation of the epidermis at the coronary band. Some of them suffered from alopecia. Foot-and-mouth disease and swine vesicular disease were excluded by serological tests. Dissection revealed a multifocal bilateral symmetric poliomyelomalacia. Histological changes in the claws ranged from severe cell-decay in the germinative layer to distinctive decay of the stratum corneum. Due to damage of the claw epidermis the corium was partly exposed. Feed analysis revealed 100-fold increased selenium content in the finishing premix from the feed mill and as a result 20- to 60-fold increased selenium values in feed samples from the farm-made finisher mixture. Selenium concentration in the blood of diseased animals was 4- to 10-fold higher than normal values, which confirmed the tentative diagnosis of a selenium toxicosis.
authors.affiliation: Abteilung Veterinär-Anatomie der Universität Bern. marta.raeber@ita.unibe.ch
authors.forename: M
authors.initials: M
authors.lastname: Räber
authors.forename: T
authors.initials: T
authors.lastname: Sydler
authors.forename: U
authors.initials: U
authors.lastname: Wolfisberg
authors.forename: H
authors.initials: H
authors.lastname: Geyer
authors.forename: E
authors.initials: E
authors.lastname: Bürgi
mesh_terms: D000821:Animal Feed / Q000506:poisoning*; D000818:Animals; D001259:Ataxia / Q000139:chemically induced / Q000662:veterinary; D006724:Hoof and Claw / Q000473:pathology; D010291:Paresis / Q000139:chemically induced / Q000662:veterinary; D012643:Selenium / Q000097:blood / Q000506:poisoning*; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000473:pathology*
chemical_list: D012643:Selenium