title: A Public Health Grid (PHGrid): Architecture and value proposition for 21st century public health.
abstract: OBJECTIVE
  This manuscript describes the value of and proposal for a high-level architectural framework for a Public Health Grid (PHGrid), which the authors feel has the capability to afford the public health community a robust technology infrastructure for secure and timely data, information, and knowledge exchange, not only within the public health domain, but between public health and the overall health care system.
  
  
  METHODS
  The CDC facilitated multiple Proof-of-Concept (PoC) projects, leveraging an open-source-based software development methodology, to test four hypotheses with regard to this high-level framework. The outcomes of the four PoCs in combination with the use of the Federal Enterprise Architecture Framework (FEAF) and the newly emerging Federal Segment Architecture Methodology (FSAM) was used to develop and refine a high-level architectural framework for a Public Health Grid infrastructure.
  
  
  RESULTS
  The authors were successful in documenting a robust high-level architectural framework for a PHGrid. The documentation generated provided a level of granularity needed to validate the proposal, and included examples of both information standards and services to be implemented. Both the results of the PoCs as well as feedback from selected public health partners were used to develop the granular documentation.
  
  
  CONCLUSIONS
  A robust high-level cohesive architectural framework for a Public Health Grid (PHGrid) has been successfully articulated, with its feasibility demonstrated via multiple PoCs. In order to successfully implement this framework for a Public Health Grid, the authors recommend moving forward with a three-pronged approach focusing on interoperability and standards, streamlining the PHGrid infrastructure, and developing robust and high-impact public health services.
authors.affiliation: National Center for Public Health Informatics, CDC, Atlanta, GA 30333, USA. tsavel@cdc.gov
authors.forename: T
authors.initials: T
authors.lastname: Savel
authors.forename: K
authors.initials: K
authors.lastname: Hall
authors.forename: B
authors.initials: B
authors.lastname: Lee
authors.forename: V
authors.initials: V
authors.lastname: McMullin
authors.forename: M
authors.initials: M
authors.lastname: Miles
authors.forename: J
authors.initials: J
authors.lastname: Stinn
authors.forename: P
authors.initials: P
authors.lastname: White
authors.forename: D
authors.initials: D
authors.lastname: Washington
authors.forename: T
authors.initials: T
authors.lastname: Boyd
authors.forename: L
authors.initials: L
authors.lastname: Lenert
mesh_terms: D002487:Centers for Disease Control and Prevention, U.S. / Q000458:organization & administration*; D033181:Information Dissemination / Q000379:methods*; D020407:Internet / Q000458:organization & administration*; D009937:Organizational Objectives; D011635:Public Health Administration / Q000379:methods*; D014481:United States