Interleukin 6 activity associated with a cardiac lymphoma.
Primary cardiac B-cell lymphoma is an extremely rare heart tumor that may be difficult to diagnose because of nonspecific clinical manifestations. Cardiac myxomas and mediastinal lymphomas show increased levels of serum cytokines, which correlate with symptoms and tumor size. We present a case of an intracardiac large B-cell lymphoma in a 75-year-old woman who had high serum levels of interleukin 6 that decreased after tumor excision. These data suggest a possible correlation between cardiac B lymphoma symptoms and interleukin 6 overproduction.
Chiavarelli
Mario
M
Division of Cardiac Surgery, University Hospital Le Scotte, Viale Bracci, Siena, Italy. chiavarelli@unisi.it
Borrelli
Emma
E
Gandolfo
Fabrizio
F
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D006348:Cardiac Surgical Procedures / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006338:Heart Neoplasms / Q000097:blood*; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000097:blood* / Q000601:surgery; D012720:Severity of Illness Index
D014408:Biomarkers, Tumor; D015850:Interleukin-6