Papuabalanols A and B, new tannins from Balanophora papuana.
Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.
Hosoya
Takahiro
T
Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.
Nakata
Asami
A
Zaima
Kazumasa
K
Latip
Jalifah
J
Din
Laily Bin
LB
Muslim
Noramly
N
Morita
Hiroshi
H
D000818:Animals; D031111:Balanophoraceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D013634:Tannins / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D004791:Enzyme Inhibitors; D010936:Plant Extracts; D013634:Tannins; D014665:Vasodilator Agents; C551763:papuabalanol A; C551764:papuabalanol B