The other end of the rainbow: infrared and skin.
Although infrared radiation (IRR) is ubiquitous in the terrestrial milieu, its effects on human skin have until now been largely ignored. Recent studies suggest an important role for infrared A (IRA) radiation (760-1440 nm) in dermal inflammation, photoaging, and photocarcinogenesis. In this issue, Calles et al. identify and analyze the IRA-induced transcriptome in human dermal fibroblasts. Their work paves the way for new research directions in IRA photobiology and raises important clinical questions regarding photoprotection and IRR-based dermatotherapy.
Holzer
Aton M
AM
Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue S., Birmingham, AL 35294, USA.
Athar
Mohammad
M
Elmets
Craig A
CA
D005347:Fibroblasts / Q000528:radiation effects*; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000528:radiation effects*; D006801:Humans; D007259:Infrared Rays; D009381:Neoplasms, Radiation-Induced / Q000235:genetics; D018462:Photobiology; D011855:Radiodermatitis / Q000235:genetics; D012867:Skin / Q000528:radiation effects*; D015595:Skin Aging / Q000235:genetics / Q000528:radiation effects; D012878:Skin Neoplasms / Q000235:genetics
CA Cancer J Clin. 1979 May-Jun;29(3):169-71
109172
Int J Cancer. 1996 Jun 21;69(3):174-9
8682583
J Am Acad Dermatol. 2007 Mar;56(3):432-8
17239987
Photochem Photobiol. 2002 Mar;75(3):296-301
11950096
Arch Dermatol Res. 1982;272(3-4):229-38
7165330
J Drugs Dermatol. 2009 Aug;8(8):708-12
19663107
Ann Dermatol Venereol. 2004 Jun-Jul;131(6-7 Pt 1):575-7
15318141
Oncogene. 2006 Aug 31;25(39):5416-25
16619044
Skin Pharmacol Physiol. 2010;23(1):15-7
20090404
Exp Mol Pathol. 2007 Dec;83(3):413-8
17599830
Photochem Photobiol. 2008 Mar-Apr;84(2):450-62
18248499
Dermatol Surg. 2009 Jul;35(7):1099-104
19438688
Nat Rev Cancer. 2009 Nov;9(11):798-809
19851315
Dermatol Monatsschr. 1990;176(11):683-6
2083608
J Rehabil Res Dev. 2009;46(4):543-54
19882488
Photomed Laser Surg. 2010 Jun;28(3):291-325
19995230
Photodermatol Photoimmunol Photomed. 2003 Oct;19(5):228-34
14535893
Natl Cancer Inst Monogr. 1978 Dec;(50):27-9
753977
J Invest Dermatol. 2008 Oct;128(10):2491-7
18449210
Adv Wound Care. 1999 Jan-Feb;12(1):35-40
10326355
Skin Pharmacol Physiol. 2009;22(1):31-44
19122479
J Exp Med. 2005 Jan 17;201(2):173-9
15657287
J Photochem Photobiol B. 2009 Mar 3;94(3):164-70
19135383
J Invest Dermatol. 2009 May;129(5):1271-9
19037232
J Invest Dermatol. 2010 Feb;130(2):554-62
19727119
Photochem Photobiol. 2008 Sep-Oct;84(5):1091-9
18651871