Highly active gold-based catalyst for the reaction of benzaldehyde with ethyl diazoacetate.
The gold complex [IPrAu(NCMe)]BF(4) catalyzes the reaction of ethyl diazoacetate with benzaldehyde to give mixtures of ethyl 3-oxo-3-phenylpropanoate and ethyl 3-hydroxy-2-phenylacrylate in the first example of a group 11 metal-based catalyst for this transformation; the catalyst activity is improved by a factor of 2500 compared to those of previously reported iron-based catalysts.
Fructos
Manuel R
MR
Laboratorio de Catálisis Homogénea, Departamento de Química y Ciencia de los Materiales, Unidad Asociada al CSIC, Universidad de Huelva, Campus de El Carmen, 21007-Huelva, Spain.
Díaz-Requejo
M Mar
MM
Pérez
Pedro J
PJ
D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D003979:Diazonium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*
D001547:Benzaldehydes; D003979:Diazonium Compounds; D050607:Organogold Compounds; C032111:diazoacetic ester; C032175:benzaldehyde