title: Temporal gliosarcoma with extraneural metastasis: case report.
abstract: A 51-year-old woman presented with a rare case of temporal gliosarcoma manifesting as a 2-month history of headache that rapidly penetrated the middle fossa floor postoperatively and metastasized to the lung. The tumor included an anteroinferior component consisting of a sarcomatous lesion adjacent to the middle fossa floor, and a posterosuperior component consisting of a gliomatous lesion. The MIB-1 index of the sarcomatous component was 47.5%, and that of the gliomatous component was 36.5%. In addition to the highly proliferative nature of the sarcomatous component, the craniotomy with partial excision of the dura mater might have accelerated the tumor penetration through the temporal base and the hematogenous metastasis to the lung.
authors.affiliation: Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Maeda
authors.forename: Takahito
authors.initials: T
authors.lastname: Miyazawa
authors.forename: Terushige
authors.initials: T
authors.lastname: Toyooka
authors.forename: Katsuji
authors.initials: K
authors.lastname: Shima
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D018316:Gliosarcoma / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D018193:Neoplasms, Complex and Mixed / Q000473:pathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000556:secondary* / Q000601:surgery; D013702:Temporal Lobe / Q000473:pathology