Perfusion MRI demonstrates crossed-cerebellar diaschisis in sickle cell disease.
Arterial spin labeling is a fully noninvasive magnetic resonance perfusion imaging method, ideally suited to pediatric perfusion imaging. We describe an 8-year-old boy with sickle cell disease, extensive right-hemispheric cerebral infarction, and crossed-cerebellar diaschisis apparent on arterial spin labeling perfusion magnetic resonance imaging. To our knowledge, this is the first case of crossed-cerebellar diaschisis demonstrated with arterial spin labeling, highlighting the potential value of perfusion magnetic resonance imaging in the clinical evaluation and follow-up of crossed-cerebellar diaschisis, and the suitability of arterial spin labeling methods for routine perfusion imaging in pediatric patients.
O'Gorman
Ruth L
RL
Department of Neuroradiology, King's College Hospital, London, United Kingdom. ruth.ogorman@kcl.ac.uk
Siddiqui
Ata
A
Alsop
David C
DC
Jarosz
Jozef M
JM
D000755:Anemia, Sickle Cell / Q000150:complications / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D002544:Cerebral Infarction / Q000150:complications / Q000473:pathology*; D054022:Cerebrum / Q000473:pathology; D002648:Child; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D012720:Severity of Illness Index