[Three-year follow up of metabolic control in adolescents with type 1 diabetes with and without eating disorders].
Eating disorders associated to type 1 diabetes (T1D) raise the risk of impairments in metabolic control increasing short and long term complications.


OBJECTIVE
To compare the glycosylated hemoglobin (HbA1c) levels variation in a group of T1D adolescents with and without disordered eating behaviour (DEB) during 3-year follow-up and to relate the metabolic control, with pubertal stage, T1D duration, Body Mass Index and gender at the end of the study.


METHODS
Analytyc an observational comparative study of two cohorts: patients were selected from a previous multicentric study done by the Paediatric Committee of the Argentinean Diabetes Association. One DEB sample group and another group without DEB were conformed. HbA1c levels were estimated al baseline and after 3 years. Pubertal stage, BMI, gender and duration of T1D were assessed at the end of the study. Comparison of statistical tests of HbA1c levels and association tests were made.


RESULTS
Eighty seven patients, 22 with DEB and 65 without DEB were studied. Patient's mean ages (13.6 vs.14.3 years) and T1D evolution time (4.0 vs. 4.7 years) were similar in both groups. Three years later, there was an increase in the mean HbA1c levels in both groups, with statistical differences only in the DEB group (8.40 vs. 9.93) (p: 0.001), but not in the group without DEB [8.57 vs. 9.01 (p: 0.06)]. An association between metabolic control and the presence of DEB was observed but not with the other studied variables.


CONCLUSIONS
Presence and persistence DEB in T1D patients implies a worsening prognosis of the metabolic control in the future.
Figueroa Sobrero
Angela
A
Hospital Materno Infantil San Roque, Paraná. figueroasobrero@arnet.com.ar
Evangelista
Patricia
P
Mazza
Carmen
C
Basso
Pablo
P
López
Stella M
SM
Scaiola
Edith
E
Honf
Margarita
M
Ferraro
Mabel
M
Eandi
María L
ML
Walz
Florencia
F
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000150:complications; D001068:Feeding and Eating Disorders / Q000097:blood* / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D013997:Time Factors
D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human