title: Zn(OTf)(2)-catalyzed addition of amines to carbodiimides: efficient synthesis of guanidines and unpredicted formation of Zn-N amido species.
abstract: Zn(OTf)(2) acts as an excellent catalyst precursor for addition of various amine N-H bonds to carbodiimides under an atmosphere of air, offering a convenient synthesis of substituted guanidines with high functional-group tolerance. A Zn-N amido species is shown to act as the active species.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.
authors.forename: Dongzhen
authors.initials: D
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Guang
authors.forename: Wen-Xiong
authors.initials: WX
authors.lastname: Zhang
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Xi
mesh_terms: D000588:Amines / Q000737:chemistry*; D002234:Carbodiimides / Q000737:chemistry*; D002384:Catalysis; D006146:Guanidines / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D017967:Zinc Compounds / Q000737:chemistry*
chemical_list: D000588:Amines; D002234:Carbodiimides; D006146:Guanidines; D017967:Zinc Compounds