title: [How radical nephrectomy compares to partial nephrectomy for the treatment of pT1a papillary renal cell carcinomas?].
abstract: OBJECTIVE
  Our objective was to compare oncologic results of nephron sparing surgery (NSS) versus radical nephrectomy (RN) in T1aN0-x M0 papillary renal cell carcinoma (PRCC).
  
  
  METHODS
  We retrospectively reviewed 277 patients treated for a pT1aN0M0 PRCC selected from an academic database from 12 centres. We compared the clinico-pathological features by using Chi-square and Student statistical analyses. Survivals analyses using Kaplan-Meier and Log-rank models were performed.
  
  
  RESULTS
  The two groups were composed by 186 patients treated by NSS and 91 by RN. The TNM stage was fixed and the two groups were, in terms of age and Fuhrman grade, comparable. Median age at diagnosis was 59 years (27-85). Median tumor size was 2.7 cm (0.4-4). The average follow-up was 49 months (1-246). Very few events arose in both groups: two local recurrences were observed in the NSS group (1.07%), three patients died of cancer in the NSS treated group (1.6%) and five in the RN treated group (5.5%). The five and 10 cancer-specific survival rate were comparable in the two groups (98% vs. 100% and 98% vs. 97%). The specific survival curves were perfectly similar for both groups (log rank test, p=0.25).
  
  
  CONCLUSIONS
  NSS is equivalent to RN as far as oncologic control of pT1aN0M0 PRCC is concerned.
authors.affiliation: UMR 60-61 CNRS, service d'urologie, CHU de Rennes, université Rennes 1, 2 rue Henri-Le-Guilloux, Rennes, France.
authors.forename: P
authors.initials: P
authors.lastname: Bigot
authors.forename: J-C
authors.initials: JC
authors.lastname: Bernhard
authors.forename: M
authors.initials: M
authors.lastname: Crepel
authors.forename: K
authors.initials: K
authors.lastname: Bensalah
authors.forename: A-R
authors.initials: AR
authors.lastname: Azzouzi
authors.forename: A
authors.initials: A
authors.lastname: de la Taille
authors.forename: L
authors.initials: L
authors.lastname: Salomon
authors.forename: J
authors.initials: J
authors.lastname: Tostain
authors.forename: V
authors.initials: V
authors.lastname: Ficarra
authors.forename: A-J
authors.initials: AJ
authors.lastname: Pantuck
authors.forename: A-S
authors.initials: AS
authors.lastname: Belldegrun
authors.forename: A
authors.initials: A
authors.lastname: Méjean
authors.forename: J-M
authors.initials: JM
authors.lastname: Ferrière
authors.forename: C
authors.initials: C
authors.lastname: Pfister
authors.forename: B
authors.initials: B
authors.lastname: Albouy
authors.forename: M
authors.initials: M
authors.lastname: Colombel
authors.forename: L
authors.initials: L
authors.lastname: Zini
authors.forename: A
authors.initials: A
authors.lastname: Villers
authors.forename: F
authors.initials: F
authors.lastname: Montorsi
authors.forename: S
authors.initials: S
authors.lastname: Shariat
authors.forename: N
authors.initials: N
authors.lastname: Rioux-Leclercq
authors.forename: J-J
authors.initials: JJ
authors.lastname: Patard
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies