How pathologic staging informs the surgical management of primary cutaneous melanoma.
In this brief review, the authors will summarize recent changes in the American Joint Committee on Cancer (AJCC) staging system, with a particular emphasis on the prognostic importance of mitotic rate and microsatellitosis, and address continuing controversial aspects of the surgical management of cutaneous melanoma.
Tsai
S
S
Department of Surgery, Division of Surgical Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Balch
C M
CM
D001706:Biopsy / Q000379:methods; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000379:methods