New acute treatments for headache.
Although we have several acute care medications for the treatment of migraine, we are always looking for new medications to treat our patients. Patients often say that their headaches are not under optimal control and would be happy to try another medication. Patients look for faster onset of relief, more complete relief, no recurrent headache and no adverse events. This article will cover some new and some anticipated acute care products, CGRP antagonists, sumatriptan by iontophoretic patch, sumatriptan by needle-free injections, DHE by oral inhalation and diclofenac potassium in a sachet. Botulinum toxin therapy, although a preventive measure, will be mentioned at the end.
Rapoport
Alan M
AM
The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. alanrapoport@gmail.com
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004008:Diclofenac / Q000008:administration & dosage / Q000627:therapeutic use; D004151:Dipeptides / Q000627:therapeutic use*; D004333:Drug Administration Routes; D020773:Headache Disorders / Q000188:drug therapy*; D006801:Humans; D010879:Piperazines; D011799:Quinazolines / Q000627:therapeutic use*; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D018170:Sumatriptan / Q000008:administration & dosage* / Q000627:therapeutic use; D016896:Treatment Outcome; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004151:Dipeptides; D010879:Piperazines; D011799:Quinazolines; D017366:Serotonin Receptor Agonists; D014662:Vasoconstrictor Agents; D004008:Diclofenac; D018170:Sumatriptan; D019274:Botulinum Toxins, Type A; C406305:olcegepant
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