title: Rhinitis in the geriatric population.
abstract: The current geriatric population in the United States accounts for approximately 12% of the total population and is projected to reach nearly 20% (71.5 million people) by 20301. With this expansion of the number of older adults, physicians will face the common complaint of rhinitis with increasing frequency. Nasal symptoms pose a significant burden on the health of older people and require attention to improve quality of life. Several mechanisms likely underlie the pathogenesis of rhinitis in these patients, including inflammatory conditions and the influence of aging on nasal physiology, with the potential for interaction between the two. Various treatments have been proposed to manage this condition; however, more work is needed to enhance our understanding of the pathophysiology of the various forms of geriatric rhinitis and to develop more effective therapies for this important patient population.
authors.affiliation: Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA. jpinto@surgery.bsd.uchicago.edu.
authors.forename: Jayant M
authors.initials: JM
authors.lastname: Pinto
authors.forename: Seema
authors.initials: S
authors.lastname: Jeswani
references.citation: Drugs. 1998 Jul;56(1):91-114
references.pmid: 9664202
references.citation: Curr Med Res Opin. 2007 Oct;23(10):2441-52
references.pmid: 17723160
references.citation: Allergy. 2009 Sep;64(9):1301-8
references.pmid: 19432938
references.citation: Laryngoscope. 1996 Sep;106(9 Pt 2):1-25
references.pmid: 8822730
references.citation: Am J Med. 2007 Jun;120(6):498-502
references.pmid: 17524748
references.citation: J Laryngol Otol. 1991 Mar;105(3):181-5
references.pmid: 2019802
references.citation: Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1724-8
references.pmid: 10556147
references.citation: Otolaryngol Head Neck Surg. 2004 Dec;131(6):946-9
references.pmid: 15577795
references.citation: Am J Med. 2009 Aug;122(8):747-53
references.pmid: 19540453
references.citation: Chest. 2008 Feb;133(2):412-9
references.pmid: 18252914
references.citation: Arch Fam Med. 1996 Sep;5(8):464-8
references.pmid: 8797551
references.citation: J Am Osteopath Assoc. 1999 Jul;99(7 Suppl):S7-12
references.pmid: 10478514
references.citation: Clin Geriatr Med. 2003 Feb;19(1):177-88, viii
references.pmid: 12735121
references.citation: Neuroimmunomodulation. 2008;15(4-6):224-40
references.pmid: 19047800
references.citation: Allergy Asthma Proc. 2006 Jan-Feb;27(1):9-11
references.pmid: 16598986
references.citation: J Asthma. 2009 Jun;46(5):481-5
references.pmid: 19544169
references.citation: Allergy. 2002;57 Suppl 70:5-39
references.pmid: 11990714
references.citation: J Plast Reconstr Aesthet Surg. 2008 Sep;61(9):1024-8
references.pmid: 18619934
references.citation: Int Arch Allergy Immunol. 2004 Dec;135(4):332-5
references.pmid: 15564775
references.citation: N Engl J Med. 2005 Nov 3;353(18):1934-44
references.pmid: 16267324
references.citation: J Clin Immunol. 2000 Jul;20(4):250-6
references.pmid: 10939712
references.citation: Mayo Clin Proc. 2002 Apr;77(4):350-4
references.pmid: 11936930
references.citation: J Allergy Clin Immunol. 2005 Sep;116(3):675-82
references.pmid: 16159642
references.citation: Pulm Pharmacol Ther. 2008;21(3):442-8
references.pmid: 17707667
references.citation: Drugs Aging. 2003;20(14):1011-7
references.pmid: 14651441
references.citation: Laryngoscope. 2009 Aug;119(8):1458-62
references.pmid: 19507239
references.citation: Am J Rhinol Allergy. 2009 Sep-Oct;23(5):512-7
references.pmid: 19807985
references.citation: JAMA. 2002 Jan 16;287(3):337-44
references.pmid: 11790213
references.citation: Curr Opin Otolaryngol Head Neck Surg. 2004 Jun;12(3):243-7
references.pmid: 15167037
references.citation: Praxis (Bern 1994). 2002 Feb 27;91(9):353-8
references.pmid: 11902099
references.citation: Clin Exp Allergy. 2008 Mar;38(3):393-404
references.pmid: 18201248
references.citation: Am J Rhinol Allergy. 2010 Jul-Aug;24(4):286-90
references.pmid: 20819468
references.citation: Fertil Steril. 2003 Sep;80(3):669-71
references.pmid: 12969725
references.citation: Allergy. 2004;59 Suppl 76:16-22; discussion 22-3
references.pmid: 14984552
references.citation: Allergy Asthma Proc. 2000 Sep-Oct;21(5):267-70
references.pmid: 11061034
references.citation: Allergy Asthma Proc. 2009 Mar-Apr;30(2):120-7
references.pmid: 19463202
references.citation: Lancet. 1999 Oct 23;354(9188):1435-9
references.pmid: 10543671
references.citation: Am J Rhinol. 1998 Jan-Feb;12(1):65-72
references.pmid: 9513662
references.citation: Ann Allergy Asthma Immunol. 1995 Oct;75(4):311-6
references.pmid: 7583845
references.citation: J Allergy Clin Immunol. 2001 Jul;108(1 Suppl):S2-8
references.pmid: 11449200
references.citation: J Allergy Clin Immunol. 2006 Nov;118(5):985-98
references.pmid: 17088121
references.citation: J Allergy Clin Immunol. 2000 Jun;105(6 Pt 2):S599-604
references.pmid: 10856164
references.citation: ORL J Otorhinolaryngol Relat Spec. 1994 May-Jun;56(3):157-60
references.pmid: 7515487
references.citation: Drugs Aging. 1995 Sep;7(3):168-75
references.pmid: 8535047
references.citation: Curr Allergy Asthma Rep. 2008 Apr;8(2):147-53
references.pmid: 18417057
references.citation: Clin Otolaryngol Allied Sci. 2003 Oct;28(5):381-5
references.pmid: 12969337
references.citation: Expert Opin Drug Metab Toxicol. 2009 Jan;5(1):91-102
references.pmid: 19220164
references.citation: Mov Disord. 2004 Mar;19 Suppl 8:S137-41
references.pmid: 15027066
references.citation: Rhinology. 2008 Sep;46(3):221-5
references.pmid: 18853875
references.citation: Clin Exp Allergy. 1996 Aug;26(8):868-79
references.pmid: 9011329
references.citation: Clin Exp Pharmacol Physiol. 2007 Jan-Feb;34(1-2):1-9
references.pmid: 17201728
references.citation: Am J Rhinol. 2004 Mar-Apr;18(2):125-7
references.pmid: 15152879
references.citation: Am J Rhinol. 2004 Nov-Dec;18(6):343-7
references.pmid: 15706979
references.citation: Clin Exp Allergy. 1998 Dec;28 Suppl 6:54-9
references.pmid: 9988437
references.citation: Am J Respir Crit Care Med. 2001 Mar;163(4):983-8
references.pmid: 11282777
references.citation: Arch Otolaryngol Head Neck Surg. 2003 May;129(5):584-7
references.pmid: 12759275
references.citation: J Allergy Clin Immunol. 2008 Aug;122(2 Suppl):S1-84
references.pmid: 18662584
references.citation: Acta Otolaryngol. 1983 Jul-Aug;96(1-2):175-9
references.pmid: 6613547
references.citation: Psychosom Med. 2003 Jan-Feb;65(1):63-73
references.pmid: 12554816
references.citation: Curr Allergy Asthma Rep. 2001 May;1(3):202-6
references.pmid: 11892037
references.citation: Allergol Immunopathol (Madr). 2006 Nov-Dec;34(6):257-62
references.pmid: 17173843
references.citation: J Occup Med. 1989 Jul;31(7):624-6
references.pmid: 2769459
references.citation: Arzneimittelforschung. 1995 May;45(5):576-81
references.pmid: 7612056
references.citation: J Gerontol A Biol Sci Med Sci. 2005 Mar;60(3):396-8
references.pmid: 15860481
references.citation: Cleft Palate Craniofac J. 1994 Jan;31(1):81-2
references.pmid: 8130249
references.citation: Allergy. 2004 Apr;59(4):461-4
references.pmid: 15005772
references.citation: HNO. 2009 May;57(5):466-72
references.pmid: 19387597
references.citation: Laryngoscope. 2008 Aug;118(8):1472-5
references.pmid: 18545216
references.citation: Ann Allergy Asthma Immunol. 2009 Feb;102(2):116-20
references.pmid: 19230461
references.citation: Allergy Asthma Proc. 2009 Jul-Aug;30(4):358-65
references.pmid: 19772758
references.citation: Am J Rhinol. 2007 Mar-Apr;21(2):207-13
references.pmid: 17424882
references.citation: Clin Exp Allergy. 2003 Sep;33(9):1305-24
references.pmid: 12956754
references.citation: Geriatrics. 2002 Oct;57(10):22-4, 29, 32 passim
references.pmid: 12391797
references.citation: Curr Opin Allergy Clin Immunol. 2004 Jun;4(3):159-63
references.pmid: 15126935
references.citation: Sleep. 2009 Sep;32(9):1221-8
references.pmid: 19750927
references.citation: Allergy. 2006 Jun;61(6):693-8
references.pmid: 16677237
references.citation: J Appl Physiol (1985). 2007 Sep;103(3):1082-92
references.pmid: 17569762
references.citation: Otolaryngol Head Neck Surg. 2002 Apr;126(4):382-7
references.pmid: 11997777
references.citation: Am Fam Physician. 2001 Jan 1;63(1):69-76
references.pmid: 11195772
references.citation: Am Fam Physician. 2005 Sep 15;72(6):1057-62
references.pmid: 16190503
references.citation: J Pathol. 2007 Jan;211(2):144-56
references.pmid: 17200946
references.citation: Age Ageing. 2003 Mar;32(2):154-63
references.pmid: 12615558
references.citation: Immun Ageing. 2005 May 31;2(1):9
references.pmid: 15927080
references.citation: Allergy. 1998 Feb;53(2):190-4
references.pmid: 9534919
references.citation: J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):99-107
references.pmid: 12586846
references.citation: Otolaryngol Head Neck Surg. 2003 Sep;129(3):274-9
references.pmid: 12958580
references.citation: J Laryngol Otol. 2005 Nov;119(11):843-52
references.pmid: 16354334
references.citation: Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008 Mar;22(5):201-3
references.pmid: 18476606
references.citation: Otolaryngol Clin North Am. 2004 Dec;37(6):1209-28, vii
references.pmid: 15563911
references.citation: Allergy. 2008 Jul;63(7):842-53
references.pmid: 18588549
references.citation: Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2006 Sep;20(17):777-9, 783
references.pmid: 17087112
references.citation: Ann Allergy Asthma Immunol. 2001 May;86(5):494-507; quiz 507-8
references.pmid: 11379801
references.citation: Am J Med. 2002 Dec 16;113 Suppl 9A:17S-24S
references.pmid: 12517578
references.citation: Clin Allergy Immunol. 2007;19:23-34
references.pmid: 17153005
references.citation: Prim Care Respir J. 2007 Feb;16(1):28-35
references.pmid: 17297524
references.citation: Otolaryngol Clin North Am. 1980 May;13(2):275-88
references.pmid: 7393572
references.citation: Otolaryngol Head Neck Surg. 2005 Jul;133(1):3-8
references.pmid: 16025044
references.citation: Geriatrics. 1998 Jun;53(6):76, 81-4
references.pmid: 9634108
references.citation: Clin Allergy Immunol. 2007;19:209-19
references.pmid: 17153015
references.citation: Ann Allergy Asthma Immunol. 1999 Feb;82(2):152-6
references.pmid: 10071517
references.citation: Minerva Med. 1999 Nov-Dec;90(11-12):421-7
references.pmid: 10829804
references.citation: Otolaryngol Head Neck Surg. 2003 Dec;129(6):739-50
references.pmid: 14663444
references.citation: Drugs Aging. 2005;22(4):289-96
references.pmid: 15839718
references.citation: Arch Gerontol Geriatr. 2008 May-Jun;46(3):349-57
references.pmid: 17597236
references.citation: Otolaryngol Head Neck Surg. 1990 Oct;103(4):605-9
references.pmid: 2123319
references.citation: Anat Embryol (Berl). 2003 Jul;207(1):19-27
references.pmid: 12783321
references.citation: Arch Otolaryngol Head Neck Surg. 2001 Nov;127(11):1353-6
references.pmid: 11701073
references.citation: Exp Gerontol. 2008 May;43(5):493-8
references.pmid: 18166287
references.citation: Ann Allergy Asthma Immunol. 2001 Jan;86(1):28-35
references.pmid: 11206234
references.citation: Indian J Pathol Microbiol. 2005 Jul;48(3):310-3
references.pmid: 16761739
references.citation: Drug Saf. 2008;31(2):127-41
references.pmid: 18217789
references.citation: Mech Ageing Dev. 2009 Aug;130(8):509-17
references.pmid: 19540259
references.citation: Ann Allergy Asthma Immunol. 1998 Nov;81(5 Pt 2):478-518
references.pmid: 9860027
references.citation: Am J Med. 2004 Mar 1;116(5):338-44
references.pmid: 14984820
references.citation: Respir Med. 2006 Nov;100(11):1952-9
references.pmid: 16626955
references.citation: Crit Care Nurs Q. 2008 Jan-Mar;31(1):40-5
references.pmid: 18316935
references.citation: Clin Allergy Immunol. 2007;19:335-50
references.pmid: 17153024
references.citation: Eur Ann Allergy Clin Immunol. 2005 Nov;37(9):353-6
references.pmid: 16453969