title: Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China.
abstract: In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.
authors.affiliation: Mobile post-doctoral station, Shaanxi Normal University, Xi'an, 710062, China. bfzhu2008@yahoo.com.cn
authors.forename: Bo-feng
authors.initials: BF
authors.lastname: Zhu
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
authors.forename: Chun-mei
authors.initials: CM
authors.lastname: Shen
authors.forename: Hai-xia
authors.initials: HX
authors.lastname: Qin
authors.forename: Shuan-liang
authors.initials: SL
authors.lastname: Fan
authors.forename: Li-bin
authors.initials: LB
authors.lastname: Deng
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Li-ping
authors.initials: LP
authors.lastname: Chen
authors.forename: Hong-dan
authors.initials: HD
authors.lastname: Wang
authors.forename: Zhen-yuan
authors.initials: ZY
authors.lastname: Wang
authors.forename: Rudolf
authors.initials: R
authors.lastname: Lucas
authors.forename: Zhen-min
authors.initials: ZM
authors.lastname: Lian
mesh_terms: D002681:China; D002877:Chromosomes, Human / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency / Q000235:genetics; D056426:Genetic Loci / Q000235:genetics*; D005828:Genetics, Population; D005843:Geography; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D010802:Phylogeny; D012426:Russia
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