Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus.
In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at the highest concentration (3 mg/mL) at all time points.
Tran
Nhiem
N
Department of Physics, Brown University, Providence, Rhode Island, USA.
Mir
Aparna
A
Mallik
Dhriti
D
Sinha
Arvind
A
Nayar
Suprabha
S
Webster
Thomas J
TJ
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005290:Ferric Compounds / Q000008:administration & dosage*; D008422:Materials Testing; D053758:Nanoparticles / Q000008:administration & dosage*; D010316:Particle Size; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; C000499:ferric oxide
Biomaterials. 2005 Jun;26(18):3995-4021
15626447
Cell. 2007 Sep 7;130(5):797-810
17803904
Nanomedicine. 2007 Mar;3(1):95-101
17379174
Biomaterials. 2005 May;26(15):2685-94
15585272
Exp Physiol. 1997 Mar;82(2):291-5
9129943
Langmuir. 2005 Sep 13;21(19):8858-64
16142971
Clin Imaging. 1998 May-Jun;22(3):211-5
9559234
Biomaterials. 2008 Feb;29(4):487-96
17964647
J Colloid Interface Sci. 2004 Oct 15;278(2):353-60
15450454
FEMS Immunol Med Microbiol. 2007 Aug;50(3):375-9
17537178
Environ Sci Technol. 2008 Feb 15;42(4):1262-7
18351103
FEMS Microbiol Lett. 1999 Apr 15;173(2):279-84
10227156
J Photochem Photobiol B. 2008 Jan 30;90(1):57-63
18093839
Lancet Infect Dis. 2001 Oct;1(3):147-55
11871491
Nanotechnology. 2008 Jul 2;19(26):265101
21828670
Arch Biochem Biophys. 2000 Jan 1;373(1):1-6
10620317
Emerg Infect Dis. 2001 Mar-Apr;7(2):178-82
11294701
J Magn Magn Mater. 2009 Jul;321(13):1947-1950
26405373
Environ Sci Technol. 2008 Jul 1;42(13):4927-33
18678028
J Colloid Interface Sci. 1999 Apr 15;212(2):474-482
10092379
Colloids Surf B Biointerfaces. 2005 Jun 10;43(1):7-11
15885991
Biomaterials. 2004 Aug;25(18):4135-48
15046904
Water Res. 2009 Mar;43(4):1027-32
19073336
Int J Nanomedicine. 2009;4:145-52
19774113