title: Fabrication of carbonate apatite block based on internal dissolution-precipitation reaction of dicalcium phosphate and calcium carbonate.
abstract: In this study, we investigated a novel method for fabrication of carbonate apatite block without ionic movement between precursor and solution by using precursor that includes all constituent ions of carbonate apatite. A powder mixture prepared from dicalcium phosphate anhydrous and calcite at appropriate Ca/P ratios (1.5, 1.67, and 1.8) was used as starting material. For preparation of specimens, the slurry made from the powder mixture and distilled water was packed in a split stainless steel mold and heat - treated, ranging from 60 degrees C to 100 degrees C up to 48 hours at 100% humidity. It appeared that carbonate apatite could be obtained above 70 degrees C and monophasic carbonate apatite could be obtained from the powder mixture at Ca/P ratio of 1.67. Carbonate content of the specimen was about 5-7%. Diametral tensile strength of the carbonate apatite blocks slightly decreased with increasing treatment temperature. The decrease in diametral tensile strength is thought to be related to the crystal size of the carbonate apatite formed.
authors.affiliation: Department of Biomaterials, Faculty of Dental Science, Kyushu University, Higashi-ku, Fukuoka, Japan. d10f1@dent.kyushu-u.ac.jp
authors.forename: Fumikazu
authors.initials: F
authors.lastname: Daitou
authors.forename: Michito
authors.initials: M
authors.lastname: Maruta
authors.forename: Giichiro
authors.initials: G
authors.lastname: Kawachi
authors.forename: Kanji
authors.initials: K
authors.lastname: Tsuru
authors.forename: Shigeki
authors.initials: S
authors.lastname: Matsuya
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Terada
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D001031:Apatites / Q000138:chemical synthesis*; D018786:Bone Substitutes / Q000138:chemical synthesis*; D002119:Calcium Carbonate / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry; D003799:Dental Stress Analysis; D008422:Materials Testing; D055595:Mechanical Phenomena; D008855:Microscopy, Electron, Scanning; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D002130:Calcium Phosphates; C030782:carboapatite; D002119:Calcium Carbonate