title: Organochlorine pesticide levels in adipose tissue of pregnant women in Veracruz, Mexico.
abstract: DDT and Lindane (gamma-HCH) which were used until 1999 in Mexico, have provided great benefits in the combat of vectors that spread infection-borne diseases and in agriculture for crop protection. The persistence in the environment and their accumulative properties results in bioconcentration in lipid rich tissues of the human body that reflect the extent of environmental pollution. Human adipose tissue samples were taken during 2009 from abdominal cavities of 69 pregnant women by cesarean surgery and from 34 samples of control donors by autopsy in Veracruz State. The samples were analyzed by gas chromatography with ECD. The results of mean levels (mg/kg on fat basis) were higher in controls compared to pregnant women beta-HCH 0.064 vs 0.027; pp'DDE 1.187 vs. 0.745; op'DDT 0.016 vs. 0.011; pp'DDT 0.117 vs. 0.099 and Sigma-DDT 1.337 vs. 0.854. The pregnant women group was divided according to age: up to 20, 20-30, and more than 30 years, and presented an increase for the more persistent pesticides with age in terms of mean concentrations and a more pronounced higher correlation in medians levels. Pairing Body Mass Index to organochlorine pesticide mean levels revealed no correlation between these factors in pregnant women.
authors.affiliation: Biomedical Sciences Doctor Study, University of Veracruz, Xalapa, Mexico.
authors.forename: Margarita
authors.initials: M
authors.lastname: Herrero-Mercado
authors.forename: S M
authors.initials: SM
authors.lastname: Waliszewski
authors.forename: R
authors.initials: R
authors.lastname: Valencia-Quintana
authors.forename: M
authors.initials: M
authors.lastname: Caba
authors.forename: F
authors.initials: F
authors.lastname: Hernández-Chalate
authors.forename: E
authors.initials: E
authors.lastname: García-Aguilar
authors.forename: R
authors.initials: R
authors.lastname: Villalba
mesh_terms: D050153:Abdominal Fat / Q000378:metabolism*; D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D002585:Cesarean Section; D002947:Cities; D003634:DDT / Q000032:analysis / Q000493:pharmacokinetics; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis* / Q000493:pharmacokinetics; D005260:Female; D001556:Hexachlorocyclohexane / Q000032:analysis / Q000493:pharmacokinetics; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis* / Q000493:pharmacokinetics; D018811:Maternal Exposure; D008800:Mexico; D008875:Middle Aged; D010575:Pesticides / Q000032:analysis* / Q000493:pharmacokinetics; D011247:Pregnancy; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D001556:Hexachlorocyclohexane; D003634:DDT