[Research progress on IR improvement and acting mechanisms of active ingredients of traditional Chinese medicine].
The insulin resistance (IR) and the active ingredients of traditional Chinese medicine and their mechanisms to improve IR in the last 3 years are summarized. Retrieve, classify and arrange the recent documentations of china and abroad. IR can drive the occurrence and progress of type 2 diabetes mellitus (T2DM), and there are several molecular mechanisms for the occurrence of IR. IR has been a research focus of diabetes, the control strategies of T2DM have been changed from the "hypoglycemic therapy" into "improve the IR and IR-related metabolic abnormalities, and make a comprehensive prevention and treatment of cardiovascular risk factors". It is demonstrated by experiments that a variety of active ingredients of traditional Chinese medicine can improve IR through different mechanisms to treat diabetes mellitus.
Zheng
Hua
H
School of Pharmacological Science, Jiangsu University, Zhenjiang 212013, China. zhenghuas08@126.com
Ge
Yanru
Y
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000627:therapeutic use*; D006801:Humans; D007333:Insulin Resistance; D008516:Medicine, Chinese Traditional
D004365:Drugs, Chinese Herbal