De novo artistic activity following insular-SII ischemia.
We report here the case of a female patient who developed the following behavioural changes after a brain lesion involving the left posterior insula and SII cortices. She discovered de novo artistic capabilities for painting, with an episodic and compulsive need to paint ("hyperpainting"), but also exhibited changes in her ability to feel emotions. In addition, she had a typical neuropathic pain syndrome, including provoked pain and spontaneous pain, whose intensity was worsened when she painted with cold colours. This case-report suggests some kind of synaesthesiae, which has previously been reported for other sensory modalities. These findings suggest that a cross-talk between emotional, thermosensory, pain, and motivational functions may take place during recovery, at the level of the left insular-SII cortices.
Thomas-Anterion
Catherine
C
Neurology/Neuropsychology - CM2R Unit, CHU de Saint-Etienne F-42055, France CAJ, L'Adapt-Rhône, 69007 Lyon, France INSERM U879, UCBLyon1, UJM St-Etienne, France Dpt de Neurologie, CHU de Saint-Etienne F-42055, France.
Creac'h
Christelle
C
Dionet
Elsa
E
Borg
Céline
C
Extier
Chantal
C
Faillenot
Isabelle
I
Peyron
Roland
R
D000328:Adult; D002545:Brain Ischemia / Q000150:complications / Q000503:physiopathology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D004644:Emotions; D005260:Female; D006801:Humans; D009437:Neuralgia / Q000209:etiology / Q000503:physiopathology*; D010147:Pain Measurement; D010151:Paintings / Q000523:psychology*; D010468:Perceptual Disorders / Q000209:etiology / Q000503:physiopathology*; D020521:Stroke / Q000150:complications / Q000503:physiopathology*; D013697:Thermosensing
Bantick SJ, Wise RG, Ploghaus A, Clare S, Smith SM, Tracey I. Imaging how attention modulates pain in humans using functional MRI. Brain. 2002;125:310-319.
Craig AD, Chen K, Bandy D, Reiman EM. Thermosensory activation of insular cortex. Nat Neurosci. 2000;3:184-190.
Finkelstein Y, Vardi J, Hod I. Impulsive artistic creativity as a presentation of transient cognitive alterations. Behav Med. 1991;17:91-94.
Frank GK, Oberndorfer TA, Simmons AN, Paulus MP, Fudge JL, Yang TT, Kaye WH. Sucrose activates human taste pathways differently from artificial sweetener. Neuroimage. 2008;39:1559-1569.
Frot M, Magnin M, Mauguière F, Garcia-Larrea L. Human SII and posterior insula differently encode thermal laser stimuli. Cereb Cortex. 2007;17:610-620.
García-Larrea L, Peyron R, Laurent B, Mauguière F. Association and dissociation between laser-evoked potentials and pain perception. NeuroReport. 1997;8:3785-3789.
Hanggi J, Beeli G, Oechslin MS, Jancke L. The multiple synaesthete E.S.: neuroanatomical basis of interval-taste and tone-colour synaesthesia. Neuroimage. 2008;43:192-203.
Jabbi M, Bastiaansen J, Keysers C. A common anterior insula representation of disgust observation, experience and imagination shows divergent functional connectivity pathways. PLoS ONE. 2008;3:e2939.
Lythgoe MFX, Pollak TA, Kalmus BA, De Haan M, Khean Chong W. Obsessive, prolific artistic output following subarachnoid hemorrhage. Neurology. 2005;64:397-398.
Mell JC, Howard SM, Miller BL. Art and the brain. The influence of frontotemporal dementia on an accomplished artist. Neurology. 2003;60:1707-1710.
Mendez MF. Hypergraphia for poetry in an epileptic patient. J Neuropsychiatry Clin Neurosci. 2005;17:560-561.
Miller BL, Cummings JL, Mishkin F. Emergence of artistic talent in frontotemporal dementia. Neurology. 1998;51:978-981.
Mulvenna CM, Walsh V. Synaesthesia: a supernormal integration? Trends Cogn Sci. 2005;10:350-352.
Peyron R, Schneider F, Faillenot I, Convers P, Barral FG, García-Larrea L, Laurent B. A fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain. Neurology. 2004;63:1838-1846.
Rolls ET, Grabenhorst F, Parris BA. Warm pleasant feelings in the brain. Neuroimage. 2008;41:1504-1513.
Royet JP, Plailly J, Delon-Martin C, Kareken DA, Segebarth C. FMRI of emotional responses to odors: influence of hedonic valence and judgment, handedness, and gender. Neuroimage. 2003;20:713-728.
Seifert F, Maihöfner C. Representation of cold allodynia in the human brain – a functional MRI study. NeuroImage. 2007;35:1168-1180.
Sellal F, Musacchio M. Créativité artistique et démence. PNPV. 2008;6:57-66.
Schrag A, Trimble M. Poetic talent unmasked by treatment of Parkinson's disease. Mov Disord. 2001;16:1175-1176.
Thomas-Antérion C, Honoré S, Dirson S, Farget-Broisin K, Laurent B. Alone cow boy's thoughts. Neurology. 2002;59:1812-1813.
Valet M, Sprenger T, Boecker H. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain – an fMRI analysis. Pain. 2004;109:399-408.
Weiss PH, Fink GR. Grapheme-colour synaesthetes show increased grey matter volumes of parietal and fusiform cortex. Brain. 2009;132:65-70.
Witt K, Krack P, Deuschl G. Change in artistic expression related to subthalamic stimulation. J Neurol. 2006;253:955-956.