title: Genetic analysis of 10 X-STRs in Argentinian population.
abstract: A set of 200 samples, 100 males and 100 females, obtained from unrelated Argentinean donors were analyzed using 10 X-STRs-DXS8378, DXS9898, DXS7133, GATA31E08, GATA172D05, DXS7423, DXS6809, DXS7132, DXS9902 and DXS6789-in order to obtain allele frequencies. Statistical analysis was performed using Powerstats and Arlequin software. The population showed no deviation from Hardy Weinberg equilibrium at all loci analyzed. Allele frequencies were compared with Spanish and Portuguese sample sets showing no statistical significant differences in four of the 10 markers analyzed. The most polymorphic marker was DXS6809 and the high values of combined power of exclusion (99.9993355% in trios and 99.9715450% in duos) reinforce the usefulness of this set of markers for kinship test and human identification.
authors.affiliation: Cátedra de Genética y Biología Molecular, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Bobillo
authors.forename: Andrea
authors.initials: A
authors.lastname: Sala
authors.forename: Leonor
authors.initials: L
authors.lastname: Gusmão
authors.forename: Daniel
authors.initials: D
authors.lastname: Corach
mesh_terms: D000483:Alleles; D001118:Argentina; D041321:Chromosomes, Human, X; D016172:DNA Fingerprinting; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006239:Haplotypes; D006579:Heterozygote; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011153:Population / Q000235:genetics*; D012015:Reference Standards; D020080:Tandem Repeat Sequences
chemical_list: D005819:Genetic Markers