title: Factors affecting pattern of care and survival in a population-based cohort of non-small-cell lung cancer incident cases.
abstract: OBJECTIVE
  To analyze the role of sociodemographic factors as determinants of the initial pattern of care and survival in incident NSCLC cases.
  
  
  METHODS
  We linked 2298 incident NSCLC cases, identified by the Piedmont Cancer Registry of Turin (PCRT) with administrative health records to identify the initial pattern of care. Because stage of disease strongly influences pattern of care and prognosis of NSCLC, all the analyses were stratified according to stage (early and advanced). The association between the set of patient's characteristics and the probability of accessing a specific pattern of care was analysed with a multivariable multinomial logistic regression model. Survival was analysed with the Cox proportional hazard model.
  
  
  RESULTS
  In the early stage group, presence of comorbidities, older age and low educational level were all associated with a lower probability of receiving surgery. These same factors, as well as being unmarried, were associated with higher probability of receiving other non-curative care only. The effects of comorbidities and low educational level as barriers to receiving more effective patterns of care were not relevant in the advanced stage group. When controlling for initial patterns of care, in the early stage group, an age older than 75 years and being unmarried were negative prognostic factors, while survival was completely independent from educational level. Among patients with an advanced stage of disease, only comorbidities had a negative impact on survival.
  
  
  CONCLUSIONS
  Appropriate lung cancer care is affected by sociodemographic factors. Greater attention to social and health programs is recommended to improve the timeliness of diagnosis, the staging of potentially resectable patients, and to implement more comprehensive multidisciplinary evaluations of those who may benefit from curative treatments.
authors.affiliation: University of Turin, Italy. evapagano@yahoo.com
authors.forename: Eva
authors.initials: E
authors.lastname: Pagano
authors.forename: Claudia
authors.initials: C
authors.lastname: Filippini
authors.forename: Daniela
authors.initials: D
authors.lastname: Di Cuonzo
authors.forename: Enrico
authors.initials: E
authors.lastname: Ruffini
authors.forename: Roberto
authors.initials: R
authors.lastname: Zanetti
authors.forename: Stefano
authors.initials: S
authors.lastname: Rosso
authors.forename: Oscar
authors.initials: O
authors.lastname: Bertetto
authors.forename: Franco
authors.initials: F
authors.lastname: Merletti
authors.forename: Giovannino
authors.initials: G
authors.lastname: Ciccone
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality* / Q000628:therapy; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003695:Delivery of Health Care / Q000592:standards*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000401:mortality* / Q000628:therapy; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011787:Quality of Health Care / Q000592:standards*; D012189:Retrospective Studies; D015996:Survival Rate