title: Population genetics of 17 Y-chromosomal STR loci in Yakutia.
abstract: Haplotype and allele frequencies of 17 Y-chromosomal short tandem repeat (Y-STR) markers in a population sample of 133 Yakut male volunteers from two regions: Central (n=41) and Western Yakutia (n=92) were determined using the AmpFlSTR Yfiler PCR Amplification Kit (Applied Biosystems). A total of 65 haplotypes were identified in the Yakut population, with 15 haplotypes in Central sample and 54 haplotypes in Western sample. Haplotype diversity values of 0.79 and 0.96, and average gene diversity values of 0.14 and 0.41 were calculated for Central and Western samples, respectively. The Fst distances between both our Yakut populations with other Russian, Siberian and Chinese populations were represented by MDS plot. The graphical view demonstrated close distances between most Yakut populations and differences with other Siberian populations.
authors.affiliation: Laboratory AMIS, FRE N°2960, CNRS/UPS, 37 Allées Jules Guesde, 31000 Toulouse, France. catheves@toulouse.inserm.fr
authors.forename: Catherine
authors.initials: C
authors.lastname: Thèves
authors.forename: Patricia
authors.initials: P
authors.lastname: Balaresque
authors.forename: Larissa E
authors.initials: LE
authors.lastname: Evdokimova
authors.forename: Innokentevich V
authors.initials: IV
authors.lastname: Timofeev
authors.forename: Anatoly N
authors.initials: AN
authors.lastname: Alekseev
authors.forename: André
authors.initials: A
authors.lastname: Sevin
authors.forename: Eric
authors.initials: E
authors.lastname: Crubézy
authors.forename: Morgane
authors.initials: M
authors.lastname: Gibert
mesh_terms: D041322:Chromosomes, Human, Y; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D016133:Polymerase Chain Reaction; D012800:Siberia