Neuropathic pain in breast cancer survivors: using the ID pain as a screening tool.
Neuropathic pain (NP) is a debilitating symptom experienced by a number of patients with cancer. We evaluated the validity of ID Pain as a screening tool for NP in breast cancer survivors using the Self-Report Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and a reported diagnosis of NP as criterion measures. Two hundred forty breast cancer survivors with a mean age of 58 years (standard deviation=16) participated in this survey. Forty-five percent of the sample reported having pain in the past week. Of those reporting pain, 33% reported that they had been diagnosed by their health care provider with NP, 39% had a positive ID Pain (> or = 2) score, and 19% had a positive S-LANSS score. The most commonly endorsed ID Pain item was "hot/burning" (n=48) followed by feeling "numb" (n=47) and "pins and needles" (n=45). Total ID Pain score was significantly associated with a clinical diagnosis of NP (r=0.41; P<0.001) and the S-LANSS total score (r=0.54; P<0.001). Receiver operating curve analysis demonstrated that ID Pain has a predictive validity of 0.72 and 0.70 for diagnosis of NP as made by clinicians and the S-LANSS, respectively. We also found that an ID Pain score greater than or equal to 2 corresponded with the likelihood of NP in this sample, consistent with the original ID Pain development study. This study provides evidence for ID Pain as a valid screening measure for NP in breast cancer survivors.
Reyes-Gibby
Cielito
C
Department of Epidemiology, Division of Cancer Prevention, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030-4009, USA. creyes@mdanderson.org
Morrow
Phuong Khanh
PK
Bennett
Michael I
MI
Jensen
Mark P
MP
Shete
Sanjay
S
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D009437:Neuralgia / Q000175:diagnosis* / Q000209:etiology; D016017:Odds Ratio; D010147:Pain Measurement; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D017741:Survivors
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