title: STAR*D: has it taught us anything about the management of depression?
abstract: OBJECTIVE
  The aim of this paper was to review the large US National Institute of Mental Health-sponsored depression intervention effectiveness study, STAR*D, in order to evaluate critically its relevance for Australasian clinicians.
  
  
  CONCLUSIONS
  STAR*D is a landmark study which tried to address issues of effectiveness rather than efficacy, of a number of interventions for depression. However, methodological shortcomings limit the utility of the study in informing Australasian clinical practice.
authors.affiliation: Department of Psychiatry, The University of Melbourne, St Vincent's Health, Fitzroy, VIC, Australia. david.castle@svhm.org.au
authors.forename: David
authors.initials: D
authors.lastname: Castle
authors.forename: Isaac
authors.initials: I
authors.lastname: Schweitzer
authors.forename: John
authors.initials: J
authors.lastname: Tiller
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015928:Cognitive Behavioral Therapy / Q000379:methods; D003131:Combined Modality Therapy / Q000379:methods; D003863:Depression / Q000188:drug therapy* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010358:Patient Participation; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012074:Remission Induction
chemical_list: D000928:Antidepressive Agents