title: Randomized comparison of multipolar, duty-cycled, bipolar-unipolar radiofrequency versus conventional catheter ablation for treatment of common atrial flutter.
abstract: BACKGROUND
  Radiofrequency (RF) catheter ablation has been established as an effective and curative treatment for atrial flutter (AFL). Approved methods include a drag-and-drop method, as well as a point-by-point ablation technique. The aim of this study was to compare the acute efficacy and procedural efficiency of a multipolar linear ablation catheter with simultaneous energy delivery to multiple catheter electrodes against conventional RF for treatment of AFL.
  
  
  METHODS
  Patients presenting to our department with symptomatic, typical AFL were enrolled consecutively and randomized to conventional RF ablation with an 8-mm tip catheter (ConvRF) or a duty-cycled, bipolar-unipolar RF generator delivering power to a hexapolar tip-versatile ablation catheter (T-VAC) group. For both groups, the procedural endpoint was bidirectional cavotricuspid isthmus block.
  
  
  RESULTS
  Sixty patients were enrolled, 30 patients each assigned to ConvRF and T-VAC groups. Total procedure time (40.2 ± 15.8 min vs 60.5 ± 12.7 min), energy delivery time (8.5 ± 3.7 min vs 14.7 ± 5.2 min), radiation dose (14.5 ± 3.5 cGy/cm² vs 31.7 ± 12.1 cGy/cm²), and the minimum number of RF applications needed to achieve block (4.2 ± 2.4 vs 8.9 ± 7.2) were significantly lower in the T-VAC group. In 7 patients treated with the T-VAC catheter, bidirectional block was achieved with less than 3 RF applications, versus no patients with conventional RF energy delivery.
  
  
  CONCLUSIONS
  The treatment of typical AFL using a hexapolar catheter with a multipolar, duty-cycled, bipolar-unipolar RF generator offers comparable effectiveness relative to conventional RF while providing improved procedural efficiency.
authors.affiliation: Department of Cardiology, University Clinic of Giessen, Giessen, Germany. ali.erdogan@innere.med.uni-giessen.de
authors.forename: Ali
authors.initials: A
authors.lastname: Erdogan
authors.forename: Norbert
authors.initials: N
authors.lastname: Guettler
authors.forename: Oliver
authors.initials: O
authors.lastname: Doerr
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Franzen
authors.forename: Nedim
authors.initials: N
authors.lastname: Soydan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bilgin
authors.forename: Pascal
authors.initials: P
authors.lastname: Vogelsang
authors.forename: Mariana
authors.initials: M
authors.lastname: Parahuleva
authors.forename: Harald
authors.initials: H
authors.lastname: Tillmanns
authors.forename: Siegbert
authors.initials: S
authors.lastname: Stracke
authors.forename: Dursun
authors.initials: D
authors.lastname: Guenduez
authors.forename: Christiane
authors.initials: C
authors.lastname: Neuhof
mesh_terms: D000368:Aged; D001282:Atrial Flutter / Q000175:diagnosis* / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome