title: [Clinical characteristics and outcome comparison between young (< or = 45 years) female and male patients with coronary artery disease undergoing percutaneous coronary intervention].
abstract: OBJECTIVE
  To compare the clinical characteristics and clinical outcomes in young (< / = 45 years) female and male coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI).
  
  
  METHODS
  Angiographic and clinical data from 124 premenopausal female patients who underwent elective PCI from April 2004 to February 2008 were compared to age-matched 430 male patients who underwent elective PCI between 2006 and 2007 in our department. All patients were treated according to guidelines and coronary angiography was repeated after 6 months. One year clinical follow-up were performed in all patients.
  
  
  RESULTS
  Incidences of dyslipidemia, the history of myocardial infarction and smoking were significantly lower in female patients than in male patients (all P < 0.01). Left main, left anterior descending and bifurcation lesions were more common while type C lesion and right coronary lesion were less common in young female CAD group compared to young male CAD group (P < 0.01-0.05). The average lesion length in female patients was significantly longer than that in male patients [(20.36 +/- 13.37) mm vs. (23.04 +/- 13.86) mm, P < 0.05]. The in-hospital and follow-up incidences of major adverse cardiac events, stent thrombosis and in-stent restenosis were similar between young female and male CAD patients.
  
  
  CONCLUSIONS
  CAD risk factors were less and vessel lesions were more likely to be found at left main, left anterior descending and bifurcation in young female CAD patients compared to young male CAD patients. The clinical outcomes were similar between young female and male CAD patients.
authors.affiliation: Coronary Heart Disease Center, Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
authors.forename: Jing-han
authors.initials: JH
authors.lastname: Huang
authors.forename: Shu-bin
authors.initials: SB
authors.lastname: Qiao
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.forename: Jian-jun
authors.initials: JJ
authors.lastname: Li
authors.forename: Jue
authors.initials: J
authors.lastname: Chen
authors.forename: Hai-bo
authors.initials: HB
authors.lastname: Liu
authors.forename: Yue-jin
authors.initials: YJ
authors.lastname: Yang
authors.forename: Min
authors.initials: M
authors.lastname: Yao
authors.forename: Yong-jian
authors.initials: YJ
authors.lastname: Wu
authors.forename: Jin-qing
authors.initials: JQ
authors.lastname: Yuan
authors.forename: Xue-wen
authors.initials: XW
authors.lastname: Qin
authors.forename: Yuan
authors.initials: Y
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Dai
authors.forename: Shi-jie
authors.initials: SJ
authors.lastname: You
authors.forename: Feng-huan
authors.initials: FH
authors.lastname: Hu
authors.forename: Wei-hua
authors.initials: WH
authors.lastname: Ma
authors.forename: Jie
authors.initials: J
authors.lastname: Qian
authors.forename: Pei
authors.initials: P
authors.lastname: Zhang
authors.forename: Ke-fei
authors.initials: KF
authors.lastname: Dou
authors.forename: Ji-lin
authors.initials: JL
authors.lastname: Chen
authors.forename: Zai-jia
authors.initials: ZJ
authors.lastname: Chen
authors.forename: Run-lin
authors.initials: RL
authors.lastname: Gao
mesh_terms: D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome