title: Corneal hysteresis, corneal resistance factor, and intraocular pressure measurement in patients with scleroderma using the reichert ocular response analyzer.
abstract: OBJECTIVE
  The Reichert ocular response analyzer (ORA) measures corneal biomechanical properties in vivo by monitoring and analyzing the corneal behavior when its structure is submitted to a force induced by an air jet. This study was designed to examine corneal biomechanical properties and intraocular pressure in patients with systemic sclerosis (SSc) and to compare with control eyes.
  
  
  METHODS
  ORA measurements were performed on the right eyes of 29 patients with SSc (group 1) and 29 healthy people who served as the control group (group 2). Corneal hysteresis, corneal resistance factor (CRF), and intraocular pressure [Goldmann correlated (IOPg) and corneal compensated] were recorded with ORA.
  
  
  RESULTS
  Mean age of patients with SSc and control groups were 51.7 +/- 11.1 and 50.3 +/- 10.8 years, respectively. Mean (+/-SD) of the corneal hysteresis and CRF readings were 9.8 +/- 1.7 versus 9.5 +/- 1.2 mm Hg (P > 0.05) and 10.0 +/- 1.5 versus 9.2 +/- 1.4 mm Hg (P < 0.05), in groups 1 and 2, respectively. Mean (+/-SD) of the IOPg and intraocular pressure corneal-compensated recordings were 15.9 +/- 2.5 versus 14.1 +/- 2.4 mm Hg (P < 0.05) and 16.9 +/- 3.2 versus 15.6 +/- 2.9 mm Hg (P > 0.05), in groups 1 and 2, respectively. Statistical analysis revealed significant differences for CRF and IOPg between the study groups.
  
  
  CONCLUSIONS
  The mean CRF and IOPg values of patients with SSc were higher when compared with normal controls. According to the results of our study, one can conclude that corneal biomechanical properties would be changed in patients with SSc and this can be determined by CRF.
authors.affiliation: Department of Ophthalmology, School of Medicine, Celal Bayar University, Manisa, Turkey. mdsinanemre@yahoo.com
authors.forename: Sinan
authors.initials: S
authors.lastname: Emre
authors.forename: Ozcan
authors.initials: O
authors.lastname: Kayikçioğlu
authors.forename: Halil
authors.initials: H
authors.lastname: Ateş
authors.forename: Esat
authors.initials: E
authors.lastname: Cinar
authors.forename: Nehir
authors.initials: N
authors.lastname: Inceoğlu
authors.forename: Figen
authors.initials: F
authors.lastname: Yargucu
authors.forename: Timur
authors.initials: T
authors.lastname: Pirildar
authors.forename: Fahrettin
authors.initials: F
authors.lastname: Oksel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D003315:Cornea / Q000503:physiopathology*; D004547:Elastic Tissue / Q000502:physiology*; D004548:Elasticity / Q000502:physiology; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000503:physiopathology*; D014065:Tonometry, Ocular