title: [Axillary recurrences after sentinel lymph node biopsy in initial breast cancer].
abstract: OBJECTIVE
  The aim of our study was to analyze the application of the Selective Sentinel Lymph Node Biopsy (SLNB) in early Breast Cancer of our population, through the analysis of axillary recurrences in patients with false negative sentinel node procedures without complete axillary lymphadenectomy, after a subsequent clinical follow-up.
  
  
  METHODS
  A total of 218 early Breast Cancer patients who underwent SLNB after being diagnosed of early breast cancer (T1-2N0) with complete axillary dissection only when the SLNB was positive in the histopathological analysis. In every case, a 2-day protocol was used to localize the sentinel node after injection of (⁹⁹m)Tc-Nanocolloid.
  
  
  RESULTS
  The mean subsequent clinical follow-up was 27 months. A total of 413 sentinel nodes were removed with a median of 1.89/p (range 1-5). Infiltration was detected in 33.9% of patients (59.45% macrometastasis, 22.97% micrometastasis and 17.5% Isolated Tumor Cells (ITC)) and negative for the other nodes excised after conventional lymphadenectomy in 60% of cases. In our population, there was only one case of false negative (FN) SLN due to massive lymphatic blockage, and an abnormal lymph node without uptake adjacent to the SLN was identified intraoperatively. No case of axillary recurrence was detected during an average follow-up of 27 months.
  
  
  CONCLUSIONS
  The absence of axillary recurrences in our population with negative SLNB without complete axillary dissection demonstrates the appropriate local control offered by this procedure in early Breast Cancer.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Universitario Son Dureta, Palma de Mallorca, España. catalinam.sampol@ssib.es
authors.forename: C
authors.initials: C
authors.lastname: Sampol
authors.forename: M
authors.initials: M
authors.lastname: Giménez
authors.forename: J
authors.initials: J
authors.lastname: Torrecabota
authors.forename: C
authors.initials: C
authors.lastname: Serra
authors.forename: R
authors.initials: R
authors.lastname: Canet
authors.forename: J
authors.initials: J
authors.lastname: Daumal
authors.forename: C
authors.initials: C
authors.lastname: Peña
authors.forename: L
authors.initials: L
authors.lastname: Gonzalez
authors.forename: E
authors.initials: E
authors.lastname: Hernandez
authors.forename: A
authors.initials: A
authors.lastname: Graner
authors.forename: A
authors.initials: A
authors.lastname: Pozo
authors.forename: F
authors.initials: F
authors.lastname: Vega
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005188:False Negative Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D010173:Palpation; D011877:Radionuclide Imaging; D021701:Sentinel Lymph Node Biopsy; D055815:Young Adult