EPR effect based drug design and clinical outlook for enhanced cancer chemotherapy.
Maeda
Hiroshi
H
School of Pharmaceutical Sciences, Sojo University, Ikeda, Kumamoto, Japan. hirmaeda@ph.sojo-u.ac.jp
Matsumura
Yasuhiro
Y
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D002199:Capillary Permeability; D015195:Drug Design; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000503:physiopathology*; D006801:Humans; D050997:Nanomedicine / Q000379:methods / Q000639:trends; D009369:Neoplasms / Q000188:drug therapy* / Q000503:physiopathology*
D000970:Antineoplastic Agents