A unique adolescent response to reward prediction errors.
Previous work has shown that human adolescents may be hypersensitive to rewards, but it is not known which aspect of reward processing is responsible for this. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, whereas neural decision value signals varied depending on how value was modeled. This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking.
Cohen
Jessica R
JR
Department of Psychology, University of California Los Angeles, Los Angeles, California, USA. jrcohen@berkeley.edu
Asarnow
Robert F
RF
Sabb
Fred W
FW
Bilder
Robert M
RM
Bookheimer
Susan Y
SY
Knowlton
Barbara J
BJ
Poldrack
Russell A
RA
D000293:Adolescent; D041923:Adolescent Development / Q000502:physiology; D000328:Adult; D000375:Aging / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D002648:Child; D003342:Corpus Striatum / Q000502:physiology; D003657:Decision Making / Q000502:physiology*; D030141:Feedback, Psychological / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008606:Mental Processes / Q000502:physiology*; D011337:Probability Learning; D011930:Reaction Time; D012201:Reward; D055815:Young Adult
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