Evidence-based emergency medicine: clinical synopsis. What is the appropriate antibiotic course for the treatment of urinary tract infections in children?
METHODS
The authors searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE from 1966 to 2005, and EMBASE from 1988 to 2005, without language restriction.


METHODS
Randomized and quasi-randomized controlled trials comparing short-term (2 to 4 days) with standard (7 to 14 days) oral antibiotic therapy in children aged 3 months to 18 years, with culture-proven urinary tract infections.


METHODS
Two authors independently assessed study quality and extracted data from included trials. A random-effects model was used to analyze data. Only randomized controlled trials were included; only 2 clearly described allocation concealment, whereas none of the trials defined appropriate blinding or used an intention-to-treat analysis.
Seupaul
Rawle A
RA
Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.