title: Silica nanoparticle supported lipid bilayers for gene delivery.
abstract: Silica nanoparticle supported cationic lipids can effectively bind plasmid DNAs and transfect mammalian cells with an efficiency that depends on both the particle size and lipid composition; here the gene delivery and expression process has been confirmed by confocal fluorescence microscopy.
authors.affiliation: Center for Micro-Engineered Materials, University of New Mexico, Albuquerque, NM, USA.
authors.forename: Juewen
authors.initials: J
authors.lastname: Liu
authors.forename: Alison
authors.initials: A
authors.lastname: Stace-Naughton
authors.forename: C Jeffrey
authors.initials: CJ
authors.lastname: Brinker
mesh_terms: D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000737:chemistry*; D018014:Gene Transfer Techniques; D008051:Lipid Bilayers / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D010957:Plasmids; D012822:Silicon Dioxide / Q000737:chemistry*; D014162:Transfection
chemical_list: D008051:Lipid Bilayers; D012822:Silicon Dioxide; D004247:DNA
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