title: Relationship between postoperative refractive outcomes and cataract density: multiple regression analysis.
abstract: OBJECTIVE
  To evaluate the relationship between cataract density and the deviation from the predicted refraction.
  
  
  METHODS
  Department of Ophthalmology, Nara Medical University, Kashihara, Japan.
  
  
  METHODS
  Axial length (AL) was measured in eyes with mainly nuclear cataract using partial coherence interferometry (IOLMaster). The postoperative AL was measured in pseudophakic mode. The AL difference was calculated by subtracting the postoperative AL from the preoperative AL. Cataract density was measured with the pupil dilated using anterior segment Scheimpflug imaging (EAS-1000). The predicted postoperative refraction was calculated using the SRK/T formula. The subjective refraction 3 months postoperatively was also measured. The mean absolute prediction error (MAE) (mean of absolute difference between predicted postoperative refraction and spherical equivalent of postoperative subjective refraction) was calculated. The relationship between the MAE and cataract density, age, preoperative visual acuity, anterior chamber depth, corneal radius of curvature, and AL difference was evaluated using multiple regression analysis.
  
  
  RESULTS
  In the 96 eyes evaluated, the MAE was correlated with cataract density (r = 0.37, P = .001) and the AL difference (r = 0.34, P = .003) but not with the other parameters. The AL difference was correlated with cataract density (r = 0.53, P<.0001).
  
  
  CONCLUSIONS
  The postoperative refractive outcome was affected by cataract density. This should be taken into consideration in eyes with a higher density cataract.
authors.affiliation: Department of Ophthalmology, Nara Medical University, Nara, Japan. tueda@naramed-u.ac.jp
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ueda
authors.forename: Hitoe
authors.initials: H
authors.lastname: Ikeda
authors.forename: Takeo
authors.initials: T
authors.lastname: Ota
authors.forename: Toyoaki
authors.initials: T
authors.lastname: Matsuura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Hara
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D002386:Cataract / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007368:Interferometry; D019654:Lens Implantation, Intraocular; D008027:Light; D018918:Phacoemulsification; D011184:Postoperative Period; D012029:Refraction, Ocular / Q000502:physiology*; D012044:Regression Analysis; D014792:Visual Acuity / Q000502:physiology