title: Determination and evaluation of clinically efficient stopping criteria for the multiple auditory steady-state response technique.
abstract: OBJECTIVE
  The present study aimed at establishing clinically efficient stopping criteria for a multiple 80-Hz auditory steady-state response (ASSR) system.
  
  
  METHODS
  In Experiment 1, data of 31 normal-hearing subjects were analyzed off-line to propose stopping rules. Consequently, ASSR recordings will be stopped when (1) all 8 responses reach significance and significance can be maintained for 8 consecutive sweeps; or (2) the mean noise levels were 4nV (if p-values were between 0.05 and 0.1, measurements were extended once by 8 sweeps); or (3) a maximum amount of 48 sweeps was attained; whichever occurred first. In Experiment 2, these stopping criteria were applied on 10 normal hearing and 10 hearing-impaired adults to assess the efficiency.
  
  
  RESULTS
  The application of these stopping rules resulted in ASSR threshold values that were comparable to other ASSR research. Furthermore, preliminary analysis of the response and noise amplitudes demonstrated slightly higher values for hearing impaired than normal-hearing subjects.
  
  
  CONCLUSIONS
  The proposed stopping rules can be used in adults to determine accurate ASSR thresholds within a time-frame of about 1h.
  
  
  CONCLUSIONS
  The use of these a priori stopping criteria might assist the clinician in their decision to terminate ASSR recordings.
authors.affiliation: Ghent University, Faculty of Medicine, Department of Oto-rhino-laryngology and Logopaedic-audiologic Sciences, De Pintelaan 185, B - 9000 Ghent, Belgium. Wendy.Dhaenens@ugent.be
authors.forename: Wendy
authors.initials: W
authors.lastname: D'haenens
authors.forename: Bart M
authors.initials: BM
authors.lastname: Vinck
authors.forename: Leen
authors.initials: L
authors.lastname: Maes
authors.forename: Annelies
authors.initials: A
authors.lastname: Bockstael
authors.forename: Hannah
authors.initials: H
authors.lastname: Keppler
authors.forename: Birgit
authors.initials: B
authors.lastname: Philips
authors.forename: Freya
authors.initials: F
authors.lastname: Swinnen
authors.forename: Ingeborg
authors.initials: I
authors.lastname: Dhooge
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D034381:Hearing Loss / Q000175:diagnosis* / Q000503:physiopathology; D006320:Hearing Tests / Q000379:methods*; D006801:Humans; D008297:Male; D012815:Signal Processing, Computer-Assisted