title: Home-based activity program for older people with depressive symptoms: DeLLITE--a randomized controlled trial.
abstract: OBJECTIVE
  We wanted to assess the effectiveness of a home-based physical activity program, the Depression in Late Life Intervention Trial of Exercise (DeLLITE), in improving function, quality of life, and mood in older people with depressive symptoms.
  
  
  METHODS
  We undertook a randomized controlled trial involving 193 people aged 75 years and older with depressive symptoms at enrollment who were recruited from primary health care practices in Auckland, New Zealand. Participants received either an individualized physical activity program or social visits to control for the contact time of the activity intervention delivered over 6 months. Primary outcome measures were function, a short physical performance battery comprising balance and mobility, and the Nottingham Extended Activities of Daily Living scale. Secondary outcome measures were quality of life, the Medical Outcomes Study 36-item short form, mood, Geriatric Depression Scale (GDS-15), physical activity, Auckland Heart Study Physical Activity Questionnaire, and self-report of falls. Repeated measures analyses tested the differential impact on outcomes over 12 months' follow-up.
  
  
  RESULTS
  The mean age of the participants was 81 years, and 59% were women. All participants scored in the at-risk category on the depression screen, 53% had a Diagnostic and Statistical Manual of Mental Disorders or International Classification of Diseases, Tenth Revision diagnosis of major depression or scored more than 4 on the GDS-15 at baseline, indicating moderate or severe depression. Almost all participants, 187 (97%), completed the trial. Overall there were no differences in the impact of the 2 interventions on outcomes. Mood and mental health related quality of life improved for both groups.
  
  
  CONCLUSIONS
  The DeLLITE activity program improved mood and quality of life for older people with depressive symptoms as much as the effect of social visits. Future social and activity interventions should be tested against a true usual care control.
authors.affiliation: Department of General Practice and Primary Health Care, School of Population Health, University of Auckland, Auckland, New Zealand. n.kerse@auckland.ac.nz
authors.forename: Ngaire
authors.initials: N
authors.lastname: Kerse
authors.forename: Karen J
authors.initials: KJ
authors.lastname: Hayman
authors.forename: Simon A
authors.initials: SA
authors.lastname: Moyes
authors.forename: Kathy
authors.initials: K
authors.lastname: Peri
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Robinson
authors.forename: Anthony
authors.initials: A
authors.lastname: Dowell
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Kolt
authors.forename: C Raina
authors.initials: CR
authors.lastname: Elley
authors.forename: Simon
authors.initials: S
authors.lastname: Hatcher
authors.forename: Liz
authors.initials: L
authors.lastname: Kiata
authors.forename: Janine
authors.initials: J
authors.lastname: Wiles
authors.forename: Sally
authors.initials: S
authors.lastname: Keeling
authors.forename: John
authors.initials: J
authors.lastname: Parsons
authors.forename: Bruce
authors.initials: B
authors.lastname: Arroll
mesh_terms: D000223:Adaptation, Psychological; D000339:Affect; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D005081:Exercise Therapy; D005260:Female; D015577:Geriatric Assessment; D006305:Health Status Indicators; D018575:Home Care Services, Hospital-Based; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D009043:Motor Activity; D009520:New Zealand / Q000453:epidemiology; D015397:Program Evaluation; D011594:Psychometrics; D011788:Quality of Life; D012044:Regression Analysis; D012944:Social Support; D011795:Surveys and Questionnaires
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