title: Studies on resilin-like gene products in insects.
abstract: Putative pro-resilins from 12 Drosophila species are compared with each other and with some pro-resilin-related proteins from other insect species, in an attempt to decide which structural features are likely to be important for the characteristic properties of resilins. The putative pro-resilins from the 12 Drosophila species are very similar; their structures are characterized by a chitin-binding R&R Consensus sequence of type RR-2, surrounded by two repeat-containing regions. The repeat-containing regions are assumed to be responsible for the long-range elasticity characteristic for resilin. Pronounced differences are present between the Drosophila pro-resilins and the resilin-like gene products present in other insect species. It is suggested that gene products, which are predicted both to be cuticular proteins and to possess long-range elasticity, should be classified as either putative pro-resilins or pro-resilin-like proteins. Gene products which are predicted to possess long-range elasticity, but do not contain a chitin-binding region, should not be classified as pro-resilin-like proteins until it has been established that they are cuticular proteins.
authors.affiliation: The Collstrop Foundation, The Royal Danish Academy of Sciences and Letters, H.C. Andersen Boulevard 35, 1553 Copenhagen V, Denmark. soa@royalacademy.dk
authors.forename: Svend Olav
authors.initials: SO
authors.lastname: Andersen
mesh_terms: D020816:Amino Acid Motifs; D000818:Animals; D016384:Consensus Sequence; D004330:Drosophila / Q000235:genetics*; D029721:Drosophila Proteins / Q000737:chemistry* / Q000235:genetics; D019476:Insect Proteins / Q000737:chemistry* / Q000235:genetics; D007313:Insecta / Q000235:genetics; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein
chemical_list: D029721:Drosophila Proteins; D019476:Insect Proteins; C030951:resilin