Platinum-catalyzed intramolecular hydroarylation of allenyl arenes: efficient synthesis of 1,4-dihydronaphthalenes.
An efficient synthetic method of 1,4-dihydronaphthalenes having various alkyl groups on the 4-position and/or ethoxycarbonyl group on the 2-position through selective intramolecular Pt-catalyzed 6-endo cyclohydroarylation of ethyl 2-benzyl-2,3-alkadienoates was developed. The present method could be further extended to two-fold Pt-catalyzed 6-endo and 7-endo cyclizations.
Mo
Juntae
J
National Research Laboratory for Catalytic Organic Reaction, Department of Chemistry, and Institute for Molecular Science and Fusion Technology, Kangwon National University, Chuncheon 200-701, Republic of Korea.
Lee
Phil Ho
PH
D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*
D000466:Alkadienes; D009281:Naphthalenes; D010984:Platinum; C025947:propadiene