[Malignant fibrous histiocytoma of the bladder. A literature review].
OBJECTIVE
Malignant fibrous histiocytoma (MFH) is an uncommon urinary tract tumor. This paper is intended to provide an update on its diagnostic criteria, pathological and immunohistochemical characteristics, histological classification, prognostic factors, and alternative treatments.


METHODS
All published articles on MFH of the urinary bladder have been reviewed and a descriptive study has been done.


RESULTS
Twenty-nine cases of MFH of the bladder have been reported. The most common morphological variants are storiform-fascicular (41%) and inflammatory (36%) MFH. Non-myxoid variants have a poorer prognosis. Stage T3 MFH was found in 72% of cases at the time of diagnosis. MFH local recurrence and distant metastasis rates were 50% and 25% respectively after surgical treatment only.


CONCLUSIONS
MFH of the bladder is a tumor with high local and distant recurrence rates and a low survival rate, and therefore requires early and aggressive treatment. Radical cystectomy with lymphadenectomy and adjuvant radiotherapy is considered to be the treatment of choice, eventually associated to chemotherapy.
Povo-Martín
I
I
Servicio de Urología, Hospital General de Castellón, Castellón, España. Ivanjp82@hotmail.com
Gallego-Vilar
D
D
Bosquet-Sanz
M
M
Miralles-Aguado
J
J
Gimeno-Argente
V
V
Rodrigo-Aliaga
M
M
Gallego-Gómez
J
J
D051677:Histiocytoma, Malignant Fibrous / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000628:therapy