title: Non-rigid Registration of High Angular Resolution Diffusion Images Represented by Gaussian Mixture Fields.
abstract: In this paper, we present a novel algorithm for non-rigidly registering two high angular resolution diffusion weighted MRIs (HARDI), each represented by a Gaussian mixture field (GMF). We model the non-rigid warp by a thin-plate spline and formulate the registration problem as the minimization of the L2 distance between the two given GMFs. The key mathematical contributions of this work are, (i) a closed form expression for the derivatives of this objective function with respect to the parameters of the registration and (ii) a novel and simpler re-orientation scheme based on an extension to the "Preservation of Principle Directions" technique. We present results of our algorithm's performance on several synthetic and real HARDI data sets.
authors.affiliation: CISE, University of Florida.
authors.forename: Guang
authors.initials: G
authors.lastname: Cheng
authors.forename: Baba C
authors.initials: BC
authors.lastname: Vemuri
authors.forename: Paul R
authors.initials: PR
authors.lastname: Carney
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Mareci
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