[Changes of repolarization properties of the right ventricle in hypertensive left ventricular hypertrophy].
Repolarization properties of left ventricular (LV) myocardium change during its hypertrophy of various genesis. Aim of this work was to study repolarization of epicardial surface of the right ventricle (RV) in experimental model of LV hypertrophy caused by renovascular hypertension in rats. We registered 32 unipolar electrograms on the surface of cardiac ventricles and calculated duration of activation recovery intervals for assessment of repolarization. In hypertensive rats relative LV mass was 26% greater than in control rats, while relative mass of RV was similar in both groups. Length of activation recovery intervals in hypertension was 1.7 times greater than in control group on both LV and RV surfaces. Dispersion of activation recovery intervals did not differ significantly between groups. Thus in LV hypertrophy in rats caused by renovascular hypertension electrical remodeling of myocardium occurs not only in left but also in right ventricle.
Krandycheva
V V
VV
Syktyvkar, Russia.
Kharin
S N
SN
Azarov
Ya E
YE
Shmakov
D N
DN
D000818:Animals; D004195:Disease Models, Animal; D018450:Disease Progression; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D020257:Ventricular Remodeling / Q000502:physiology*