Menstrual cycle characteristics and risk of coronary heart disease and type 2 diabetes.
In a prospective cohort study, we observed that women with a history of irregular cycles have a 28% increased coronary heart disease risk and tended to have a higher type 2 diabetes risk as compared with women who had a regular cycle length of 27 to 29 days. This association could not be explained by metabolic risk factors or altered hormone levels.
Gast
Gerrie-Cor M
GC
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. g.c.m.gast@umcutrecht.nl
Grobbee
Diederick E
DE
Smit
Henriette A
HA
Bueno-de-Mesquita
H Bas
HB
Samsioe
Göran N
GN
van der Schouw
Yvonne T
YT
D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008597:Menstrual Cycle / Q000502:physiology*; D008599:Menstruation Disturbances / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D013997:Time Factors; D055815:Young Adult