High fruit intake is associated with a lower risk of future hypertension determined by home blood pressure measurement: the OHASAMA study.
We investigate associations of fruit and vegetable intake with the risk of future hypertension using home blood pressure in a general population from Ohasama, Japan. We obtained data from 745 residents aged ≥35 years without home hypertension at baseline. Dietary intake was measured using a validated 141-item food frequency questionnaire, and subjects were then divided into quartiles according to the fruit and vegetable intake. Home hypertension was defined as home systolic/diastolic blood pressure of ≥135/85 mm Hg and/or the use of antihypertensive medication. During a 4-year follow-up period, we identified 222 incident cases of home hypertension. After adjustment for all putative confounding factors, the highest quartile of fruit intake was associated with a significantly lower risk of future home hypertension (odds ratio 0.40, 95% confidence interval 0.22-0.74, P=0.004). In conclusion, this study, based on home blood pressure measurement, suggests that higher intake of fruit is associated with a lower risk of future home hypertension.
Tsubota-Utsugi
M
M
Nutritional Epidemiology Program, National Institute of Health and Nutrition, Shinjuku-ku, Tokyo, Japan. mutsugky@nih.go.jp
Ohkubo
T
T
Kikuya
M
M
Metoki
H
H
Kurimoto
A
A
Suzuki
K
K
Fukushima
N
N
Hara
A
A
Asayama
K
K
Satoh
H
H
Tsubono
Y
Y
Imai
Y
Y
D000959:Antihypertensive Agents / Q000627:therapeutic use; D018660:Blood Pressure Monitoring, Ambulatory; D015930:Diet Records; D005260:Female; D005500:Follow-Up Studies; D005638:Fruit; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012306:Risk; D012307:Risk Factors; D014675:Vegetables
D000959:Antihypertensive Agents