title: Final report on the safety assessment of sodium cetearyl sulfate and related alkyl sulfates as used in cosmetics.
abstract: Sodium cetearyl sulfate is the sodium salt of a mixture of cetyl and stearyl sulfate. The other ingredients in this safety assessment are also alkyl salts, including ammonium coco-sulfate, ammonium myristyl sulfate, magnesium coco-sulfate, sodium cetyl sulfate, sodium coco/hydrogenated tallow sulfate, sodium coco-sulfate, sodium decyl sulfate, sodium ethylhexyl sulfate, sodium myristyl sulfate, sodium oleyl sulfate, sodium stearyl sulfate, sodium tallow sulfate, sodium tridecyl sulfate, and zinc coco-sulfate. These ingredients are surfactants used at concentrations from 0.1% to 29%, primarily in soaps and shampoos. Many of these ingredients are not in current use. The Cosmetic Ingredient Review (CIR) Expert Panel previously completed a safety assessment of sodium and ammonium lauryl sulfate. The data available for sodium lauryl sulfate and ammonium lauryl sulfate provide sufficient basis for concluding that sodium cetearyl sulfate and related alkyl sulfates are safe in the practices of use and concentration described in the safety assessment.
authors.affiliation: Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 412, Washington, DC 20036, USA. cirinfo@cir-safety.org
authors.forename: Monice
authors.initials: M
authors.lastname: Fiume
authors.forename: Wilma F
authors.initials: WF
authors.lastname: Bergfeld
authors.forename: Donald V
authors.initials: DV
authors.lastname: Belsito
authors.forename: Curtis D
authors.initials: CD
authors.lastname: Klaassen
authors.forename: James G
authors.initials: JG
authors.lastname: Marks
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Shank
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Slaga
authors.forename: Paul W
authors.initials: PW
authors.lastname: Snyder
authors.forename: F
authors.initials: F
authors.lastname: Alan Andersen
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D003257:Consumer Product Safety; D003358:Cosmetics / Q000493:pharmacokinetics / Q000633:toxicity*; D005233:Fatty Alcohols / Q000493:pharmacokinetics / Q000633:toxicity*; D006801:Humans; D018570:Risk Assessment; D013228:Stearates / Q000493:pharmacokinetics / Q000633:toxicity*; D013463:Sulfuric Acid Esters / Q000493:pharmacokinetics / Q000633:toxicity*; D018675:Toxicity Tests
chemical_list: D003358:Cosmetics; D005233:Fatty Alcohols; D013228:Stearates; D013463:Sulfuric Acid Esters; C002211:cetyl sulfate