title: Double stranded DNA discrimination by di-pyrene modified gamma-cyclodextrin.
abstract: Neutral fluorescent active di-pyrene modified gamma-cyclodextrin (1) was synthesized in order to discriminate with single and double strand DNA (ssDNA and dsDNA, respectively) with high selectivity. The binding and selectivity of 1 for dsDNA was indicated by increase of the fluorescent intensity in an addition of dsDNA. On the other hand, an increase of fluorescent intensity of 1 was not recognized in an addition of ssDNA.
authors.affiliation: Department of Material-Process and Applied Chemistry for Environments, Graduate School of Engineering and Resource Science, Akita University, Akita 010-8502, Japan.
authors.forename: Akane
authors.initials: A
authors.lastname: Takeda
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Akimoto
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kondo
authors.forename: Fumio
authors.initials: F
authors.lastname: Hamada
mesh_terms: D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D047408:gamma-Cyclodextrins / Q000737:chemistry*
chemical_list: D011721:Pyrenes; D047408:gamma-Cyclodextrins; D004247:DNA; C023792:gamma-cyclodextrin