title: Chronic recurrent multifocal osteomyelitis as the first presentation of acute lymphoblastic leukemia in a 2-year-old boy.
abstract: We present herein a 2-year-old boy who suffered from chronic recurrent multifocal osteomyelitis for 6 months and was later diagnosed as acute lymphoblastic leukemia. In view of the rarity of bilateral symmetric and multifocal lesions in osteomyelitis in children, we suggest that leukemia should be investigated with bone marrow aspiration in such patients, even if complete blood count parameters are normal, and there is no hepatosplenomegaly.
authors.affiliation: Faculty of Medicine, Pediatric Hematology Unit, Ihsan Dogramaci Children's Hospital, Hacettepe University, Ankara/Turkey. betultavil@yahoo.com
authors.forename: Betul
authors.initials: B
authors.lastname: Tavil
authors.forename: Gulten
authors.initials: G
authors.lastname: Secmeer
authors.forename: Yasemin Isk
authors.initials: YI
authors.lastname: Balc
authors.forename: Hasan
authors.initials: H
authors.lastname: Tezer
authors.forename: Cemalettin
authors.initials: C
authors.lastname: Aksoy
authors.forename: Serdar
authors.initials: S
authors.lastname: Alan
authors.forename: Fatma
authors.initials: F
authors.lastname: Gumruk
authors.forename: Sevgi
authors.initials: S
authors.lastname: Yetgin
mesh_terms: D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D011379:Prognosis; D012008:Recurrence