title: Steroidal alkaloids of Veratrum lobelianum Bernh. and Veratrum nigrum L.
abstract: Twelve steroidal alkaloids were isolated from four populations of Veratrum lobelianum Bernh. and Veratrum nigrum L. Full NMR data for veralosinine (1), and extensive 1H NMR data for veralosine (3) and teinemine (5) are presented here for the first time. (+/-)-15-O-(2-Methylbutyroyl)germine (10) is undescribed up to now. The antiproliferative activities of veranigrine, veralosinine, and neogermitrine have shown that they are a perspective for further studies.
authors.affiliation: Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. christov@orgchm.bas.bg
authors.forename: Veselin
authors.initials: V
authors.lastname: Christov
authors.forename: Bozhanka
authors.initials: B
authors.lastname: Mikhova
authors.forename: Antoaneta
authors.initials: A
authors.lastname: Ivanova
authors.forename: Julianna
authors.initials: J
authors.lastname: Serly
authors.forename: Joseph
authors.initials: J
authors.lastname: Molnar
authors.forename: Dangaa
authors.initials: D
authors.lastname: Selenge
authors.forename: Amgalan
authors.initials: A
authors.lastname: Solongo
authors.forename: Nadezhda
authors.initials: N
authors.lastname: Kostova
authors.forename: Yadamsuren
authors.initials: Y
authors.lastname: Gerelt-Od
authors.forename: Dimitar
authors.initials: D
authors.lastname: Dimitrov
mesh_terms: D000818:Animals; D002031:Bulgaria; D002455:Cell Division / Q000187:drug effects*; D007940:Leukemia L5178 / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D051379:Mice; D008958:Models, Molecular; D008986:Mongolia; D010840:Phytosterols / Q000494:pharmacology; D014703:Veratrum / Q000737:chemistry*; D014704:Veratrum Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D010840:Phytosterols; D014704:Veratrum Alkaloids; C539652:veranigrine