title: Rituximab (Rituxan).
abstract: Rituximab is a monoclonal antibody that was first approved by the FDA as an antineoplastic agent designed to treat B-cell malignancies. This article will review the mechanism of action and clinical role of this anti-B-cell agent.
authors.affiliation: Division of Pediatric Nephrology, University of Michigan Mott Children's Hospital, Ann Arbor, Michigan, USA. dselewsk@med.umich.edu
authors.forename: David T
authors.initials: DT
authors.lastname: Selewski
authors.forename: G V
authors.initials: GV
authors.lastname: Shah
authors.forename: R J
authors.initials: RJ
authors.lastname: Mody
authors.forename: P A
authors.initials: PA
authors.lastname: Rajdev
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherji
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000188:drug therapy* / Q000473:pathology; D000069283:Rituximab
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D000069283:Rituximab
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