Prevention and treatment of systemic glucocorticoid side effects.
BACKGROUND
Systemic glucocorticoids are used in dermatologic practice for various diseases including connective tissue disorders, bullous diseases, and many other dermatologic conditions. Patients with these diseases are at times treated with long-term courses of glucocorticoids, which place them at increased risk for glucocorticoid-induced side effects. Therefore, dermatologists must be knowledgeable of risks related to glucocorticoid use and be familiar with guidelines to manage them.


OBJECTIVE
To provide an update of recent advances in the prevention and treatment of major glucocorticoid-induced side effects.


METHODS
Review of the literature.


RESULTS
Data regarding the prevention and treatment of glucocorticoid-induced side effects are presented.


CONCLUSIONS
This review should help dermatologists optimally manage and prevent glucocorticoid-induced side effects.
Moghadam-Kia
Siamak
S
Philadelphia VA Hospital, Philadelphia, PA, USA.
Werth
Victoria P
VP
D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D002493:Central Nervous System Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D004700:Endocrine System Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D005260:Female; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D009140:Musculoskeletal Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D010024:Osteoporosis / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control; D012871:Skin Diseases / Q000188:drug therapy*
D005938:Glucocorticoids
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