Catalytic asymmetric Strecker hydrocyanation of imines using Yb(OTf)3-pybox catalysts.
We have explored the highly enantioselective Strecker hydrocyanation of a wide range of aromatic, alpha,beta-unsaturated, heterocyclic, and aliphatic aldimines with good to excellent conversions and ees up to 98% in the presence of catalytic amounts of Yb(OTf)(3)-pybox complexes.
Karimi
Babak
B
Department of Chemistry, Institute for Advanced Studies in Basic Sciences, PO Box 45195-1159, Gava Zang, Zanjan, Iran. karimi@iasbs.ac.ir
Maleki
Aziz
A
D002384:Catalysis; D007097:Imines / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D007097:Imines; D008698:Mesylates; D009570:Nitriles; D009942:Organometallic Compounds; C518808:ytterbium(III) triflate