[A Meta analysis: mother to infant transmission of hepatitis B virus via different combined immunoprophylaxis delivery modes].
OBJECTIVE
To evaluate the effect of different combined immunoprophylaxis delivery modes on mother to infant transmission of hepatitis B virus (HBV).


METHODS
Six hundred and ninety-six relevant literatures were collected by systematic literature search. Meta-analysis was applied to seven selected literatures that met the criteria and to assess the influence on the infant HBV transmission via different delivery patterns by infants combined immunoprophylaxis.


RESULTS
A total of 1435 cases from seven studies which met the criteria were included. The positive rate of HBV was 7.34% (61/831) among the 831 infants in the vaginal delivery group and 4.80% (29/604) among the 604 infants in the caesarean section group. There was no statistically difference between the two groups (OR = 0.70, 95%CI: 0.45 - 1.11, Z = 1.52, P = 0.13).


CONCLUSIONS
There was no significant effect of delivery modes on infant infectious rate of HBV by infants' passive and active immunization.
Wang
Hui-hua
HH
Department of Maternity, The First People's Hospital of Tongxiang, Zhejiang 314500, China.
Wang
Zheng-ping
ZP
D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control* / Q000635:transmission; D017325:Hepatitis B Vaccines / Q000627:therapeutic use; D006515:Hepatitis B virus; D006801:Humans; D007114:Immunization; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy
D017325:Hepatitis B Vaccines