title: [Acute hyperglycemia and reperfusion therapy in stroke patients].
abstract: Current acute therapies for ischemic stroke are limited. Only a small proportion of stroke patients are eligible to receive reperfusion therapy. Acute hyperglycemia has a deleterious effect in stroke patients by accelerating ischemic brain damage. The complex relationship between hyperglycemia and stroke is discussed. In tPA-treated patients, the acute but not chronic hyperglycemic state may hamper fibrinolytic process, delaying reperfusion of ischemic penumbra. Early measures to reduce hyperglycemia may favor early recanalization.
authors.affiliation: Neurologická klinika Lékarské fakulty UK a FN Hradec Králové. krajickova@fnhk.cz
authors.forename: D
authors.initials: D
authors.lastname: Krajícková
mesh_terms: D000208:Acute Disease; D002560:Cerebrovascular Circulation; D006801:Humans; D006943:Hyperglycemia / Q000150:complications*; D020521:Stroke / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D015912:Thrombolytic Therapy