title: Safety of antihistamines during pregnancy and lactation.
abstract: OBJECTIVE
  Many of my pregnant and breastfeeding patients suffer from allergies and frequently ask me about the safety of antihistamines during pregnancy and breastfeeding. Should I advise them to use the older sedating medications? I have heard that they might be safer than the newer nonsedating class of drugs. Or have the newer ones been studied as well?
  
  
  CONCLUSIONS
  First-generation antihistamines are considered safe to use during pregnancy. There are relatively fewer data on the nonsedating second-generation antihistamines; however, published studies are reassuring. All antihistamines are considered safe to use during breastfeeding, as minimal amounts are excreted in the breast milk and would not cause any adverse effects on a breastfeeding infant.
authors.forename: Miranda
authors.initials: M
authors.lastname: So
authors.forename: Pina
authors.initials: P
authors.lastname: Bozzo
authors.forename: Miho
authors.initials: M
authors.lastname: Inoue
authors.forename: Adrienne
authors.initials: A
authors.lastname: Einarson
mesh_terms: D001942:Breast Feeding; D005260:Female; D005333:Fetus / Q000187:drug effects; D006633:Histamine Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy*; D007258:Informed Consent; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
chemical_list: D006633:Histamine Antagonists
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