Synthesis of a high-purity chemical library reveals a potent inducer of oxidative stress.
Cui
Jiayue
J
Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA.
Matsumoto
Kenji
K
Wang
Cindy Y
CY
Peter
Marcus E
ME
Kozmin
Sergey A
SA
D053148:Caspase 3 / Q000378:metabolism; D053179:Caspase 7 / Q000378:metabolism; D045744:Cell Line, Tumor; D057166:High-Throughput Screening Assays; D006801:Humans; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000378:metabolism; D054852:Small Molecule Libraries / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013453:Sulfonylurea Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D017382:Reactive Oxygen Species; D054852:Small Molecule Libraries; D013453:Sulfonylurea Compounds; C005008:tolcyclamide; D053148:Caspase 3; D053179:Caspase 7
J Immunol Methods. 1991 Jun 3;139(2):271-9
1710634
Cell. 2004 Jun 11;117(6):773-86
15186778
Acta Histochem. 2001 Jul;103(3):241-51
11482370
Annu Rev Immunol. 2005;23:853-75
15771588
Nat Med. 2005 Jul;11(7):725-30
16015365
Free Radic Biol Med. 2000 Aug;29(3-4):323-33
11035261
Exp Cell Res. 1994 Apr;211(2):314-21
8143779
Nat Chem Biol. 2006 Oct;2(10):543-50
16936720
J Org Chem. 2010 Mar 5;75(5):1756-9
20141224
Cancer Res. 2003 Oct 15;63(20):6870-6
14583485
Chem Rev. 2003 Mar;103(3):893-930
12630855
J Immunol. 1992 Apr 1;148(7):2207-16
1545126
J Am Chem Soc. 2005 Jun 22;127(24):8686-96
15954774
J Biol Chem. 2002 Feb 8;277(6):4351-60
11733517