title: Scanning laser image correlation for measurement of flow.
abstract: Scanning laser image correlation (SLIC) is an optical correlation technique for measuring the fluid velocity of particles suspended in a liquid. This technique combines laser scanning of an arbitrary pattern with pair cross-correlation between any two points in the pattern. SLIC overcomes many of the limitations of other optical correlation techniques for flow measurement, such as laser speckle, spatial temporal image correlation spectroscopy, and two-foci methods. One of the main advantages of SLIC is that the concept can be applied to measurements on a range of scales through simple zooming or modifications in the instrumentation. Additionally, SLIC is relatively insensitive to instrument noise through the use of correlation analysis and is insensitive to background. SLIC can provide detailed information about the direction and pattern of flow. SLIC has potential applications ranging from microfluidics to blood flow measurements.
authors.affiliation: University of California, Irvine, Biomedical Engineering Department, 3120 Natural Sciences 2, Irvine, California 92697-2715, USA.
authors.forename: Molly J
authors.initials: MJ
authors.lastname: Rossow
authors.forename: William W
authors.initials: WW
authors.lastname: Mantulin
authors.forename: Enrico
authors.initials: E
authors.lastname: Gratton
mesh_terms: D000465:Algorithms; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000379:methods*; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation*; D018613:Microscopy, Confocal / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic
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