Cinchona alkaloid/Ti(IV)-catalyzed enantioselective enamine-trifluoropyruvate condensation-cyclization reaction and its application to drug-like heterocycles.
Ogawa
Shinichi
S
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya, 466-8555 Japan.
Iida
Norihito
N
Tokunaga
Etsuko
E
Shiro
Motoo
M
Shibata
Norio
N
D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry*; D003500:Cyclization; D005461:Fluorine / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D019289:Pyruvic Acid / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014025:Titanium / Q000737:chemistry*
D002930:Cinchona Alkaloids; D006571:Heterocyclic Compounds; D012997:Solvents; D013141:Spiro Compounds; D005461:Fluorine; D019289:Pyruvic Acid; D014025:Titanium