[Atypical carcinoid of the larynx. Case report and review of literature].
BACKGROUND
With an incidence of over 90%, squamous carcinomas are the most frequent laryngeal malignancies. Laryngeal neuroendocrine tumors appear only in approximately 1%. These are aggressive tumours with a high rate of metastases. To date, no diagnosis or treatment guidelines have been established for this entity.


METHODS
We describe the case of a 63-year-old man complaining of dysphagia and intermittent hoarseness. Initial laryngoscopy showed a tumour at the laryngeal epiglottic surface. Staging demonstrated an atypical carcinoid tumour with local lymph-node metastasis. At 24 months following revision surgery with safety distance, elective bilateral neck dissection and adjuvant radiotherapy the patient is free of complaints and recurrence.


CONCLUSIONS
In atypical carcinoid tumours total resection as well as bilateral neck dissection should be performed, even in cN0 cases. In the presence of cervical lymph node metastases adjuvant radiotherapy is indicated.
Pein
M K
MK
Universitätsklinik und Poliklinik für HNO-Heilkunde, Kopf- und Halschirurgie, Universitätsklinikum Halle, Magdeburger Strasse 12, 06112, Halle, Deutschland. katharina.pein@medizin.uni-halle.de
Holzhausen
H
H
Kösling
S
S
Bartel-Friedrich
S
S
Knipping
S
S
D001706:Biopsy; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D003680:Deglutition Disorders / Q000209:etiology; D018572:Disease-Free Survival; D006685:Hoarseness / Q000209:etiology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D007828:Laryngoscopy; D007830:Larynx / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant