Iron-mediated direct Suzuki-Miyaura reaction: a new method for the ortho-arylation of pyrrole and pyridine.
The first example of an iron-mediated direct Suzuki-Miyaura reaction between N-heterocyclic compounds and arylboronic acids is described, and both electron-rich and electron-deficient heteroarenes can be successfully used for the coupling reaction.
Wen
Jun
J
Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, PR China.
Qin
Song
S
Ma
Li-Fang
LF
Dong
Liang
L
Zhang
Ji
J
Liu
Shan-Shan
SS
Duan
Yi-Shu
YS
Chen
Shan-Yong
SY
Hu
Chang-Wei
CW
Yu
Xiao-Qi
XQ
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry*; D013237:Stereoisomerism
D001897:Boronic Acids; D006571:Heterocyclic Compounds; D011725:Pyridines; D011758:Pyrroles; D007501:Iron