title: Three-dimensional structures of RNA obtained by means of knowledge-based interaction potentials.
abstract: We derive a set of effective potentials describing the interaction between pairs of nucleotides that belong to an RNA molecule. Such interaction potentials are then used as the main constituents of a simplified simulation model, which is tested in the description of small secondary structure motifs. Our simulated RNA hairpins are consistent with the experimental structures obtained by NMR.
authors.affiliation: Departamento de Física, Centro de Investigación y de Estudios Avanzados del IPN, Apartado Postal 14-740, 07000 México, Distrito Federal, Mexico.
authors.forename: Oscar
authors.initials: O
authors.lastname: Taxilaga-Zetina
authors.forename: Patricia
authors.initials: P
authors.lastname: Pliego-Pastrana
authors.forename: Mauricio D
authors.initials: MD
authors.lastname: Carbajal-Tinoco
mesh_terms: D001483:Base Sequence; D055029:Inverted Repeat Sequences; D008954:Models, Biological; D008958:Models, Molecular; D009010:Monte Carlo Method; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*
chemical_list: D012313:RNA