Synthesis of 1,3-dialkyl-1,2,3-triazolium ionic liquids and their applications to the Baylis-Hillman reaction.
Novel 1,3-dialkyl-1,2,3-triazolium ionic liquids were synthesized via click reactions using 1-trimethylsilylacetylene and alkyl azides and were efficient reaction media for the Baylis-Hillman reaction. The problems associated with deprotonation of the C-2 hydrogen of [bmim][PF(6)] could be suppressed in the reaction of [bmTr][PF(6)] or [bmTr][NTf(2)]. 1,3-Dialkyl-1,2,3-triazolium ionic liquids are chemically inert under basic conditions and more suitable media for the reactions involving bases than the common 1,3-dialkylimidazolium ionic liquids.
Jeong
Yunkyung
Y
Center for Cell Signaling & Drug Discovery Research, College of Pharmacy and Division of Life & Pharmaceutical Sciences, Ewha Womans University, 11-1 Daehyun-Dong, Seodaemun-Gu, Seoul 120-750, Korea.
Ryu
Jae-Sang
JS
D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D052578:Ionic Liquids / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D014230:Triazoles / Q000737:chemistry*
D000473:Alkanes; D052578:Ionic Liquids; D014230:Triazoles