[The frequency of polymorphism in promoter gene coding epoxygenase 2J2 in patents with acute coronary syndrome].
G(-50) --> T promoter polymorphism of gene encoding human epoxygenase 2J2 in 107 patients with acute coronary syndrome and in 104 practically healthy people was determined. It was shown that interrelation of genotypes G/G, G/T and T/T was 91%, 9% Ta 0% correspondingly (in control--92%, 7%, 1%; P > 0.05 by chi2-test). The data indicate that epoxygenase 2J2 gene polymorphism is not a risk factor of acute coronary syndrome in Ukrainian population.
Lisovoĭ
A O
AO
Dosenko
V E
VE
Parkhomenko
A N
AN
Moĭbenko
A A
AA
D054058:Acute Coronary Syndrome / Q000201:enzymology* / Q000235:genetics*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000090762:Cytochrome P-450 CYP2J2; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D011401:Promoter Regions, Genetic; D014455:Ukraine
D003577:Cytochrome P-450 Enzyme System; D000090762:Cytochrome P-450 CYP2J2