Synthesis of an acyltrifluoroborate and its fusion with azides to form amides.
A uniquely stable acyl potassium trifluoroborate, potassium (2-phenylacetyl)trifluoroborate, has been synthesized and isolated. In the presence of an activating Lewis acid, this reagent reacts with azides to form amides in good yields.
Molander
Gary A
GA
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA. gmolandr@sas.upenn.edu
Raushel
Jessica
J
Ellis
Noel M
NM
D000577:Amides / Q000138:chemical synthesis; D001386:Azides / Q000138:chemical synthesis; D001881:Borates / Q000138:chemical synthesis* / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D015394:Molecular Structure
D000577:Amides; D001386:Azides; D001881:Borates; D005461:Fluorine