Iron-catalyzed, directed oxidative arylation of olefins with organozinc and Grignard reagents.
Chelation-controlled arylation of olefins with organozinc or Grignard reagents proceeds in the presence of an iron catalyst, under mild conditions and typically without the need of external ligands, to afford substituted olefins in high yield and with complete regio- and stereocontrol.
Ilies
Laurean
L
Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Okabe
Jun
J
Yoshikai
Naohiko
N
Nakamura
Eiichi
E
D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007202:Indicators and Reagents; D007501:Iron / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry
D000475:Alkenes; D007202:Indicators and Reagents; D007501:Iron; D008274:Magnesium; D015032:Zinc