title: Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment.
abstract: Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full-term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Gazi University, Ankara, Turkey. gtacoy@gmail.com
authors.forename: Gülten
authors.initials: G
authors.lastname: Taçoy
authors.forename: Numan Nadir
authors.initials: NN
authors.lastname: Ekim
authors.forename: Atiye
authors.initials: A
authors.lastname: Cengel
mesh_terms: D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000188:drug therapy*; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D010879:Piperazines / Q000627:therapeutic use*; D011247:Pregnancy; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate