Cutis verticis gyrata and alopecia areata: a synchronous coincidence?
Cutis verticis gyrata (CVG) is a descriptive term for a scalp condition that is convoluted folds and deep furrows that resemble the surface of the cerebral cortex. It is categorized by the underlying etiology, as primary essential, primary non-essential and secondary. Alopecia areata (AA) is a common, organ specific autoimmune disease, and most AA cases are sporadic. There is clearly a strong genetic component. There is no established relationship between CVG and AA. We report one case which was affected with essential primary CVG and alopecia areata, and suggest a possibility of genetic association between CVG and AA, possibly both being related to mutations in the fibroblast growth factor receptor 2 (FGFR2).
Yoo
Kwang Ho
KH
Department of Dermatology, College of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Korea.
Lee
Jin Woong
JW
Jang
Woo Sun
WS
Li
Kapsok
K
Seo
Seong Jun
SJ
Hong
Chang Kwun
CK
D000328:Adult; D000506:Alopecia Areata / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D012536:Scalp Dermatoses / Q000209:etiology / Q000235:genetics* / Q000473:pathology