title: Advances in local-regional treatment for patients with early-stage breast cancer: a review of the field.
abstract: This review highlights advances in the field of the local-regional treatment for patients with early-stage breast cancer. Through the years, the surgical treatment for early-stage breast cancer has evolved into more conservative treatment, with breast-conserving measures replacing the mastectomy as the most common procedure performed to treat the primary tumor. Likewise, nodal staging has evolved so that the lymphatic mapping procedures have replaced axillary dissection, resulting in a less morbid procedure and better staging information. Advances in radiation treatment have resulted in increasingly tailored approaches to adding radiation treatment after breast-conserving surgery or mastectomy. These improvements in local-regional treatment have benefitted patients through increased breast conservation treatment, improved local control, increased survival, and improved quality of life.
authors.affiliation: Department of Surgical Oncology, The Lakeland Regional Cancer Center, FL 33647, USA.
authors.forename: Christian
authors.initials: C
authors.lastname: Reintgen
authors.forename: Douglas
authors.initials: D
authors.lastname: Reintgen
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Solin
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D044584:Carcinoma, Ductal / Q000628:therapy; D055088:Early Detection of Cancer / Q000639:trends; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental / Q000639:trends; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant / Q000639:trends