title: Successful treatment of disseminated human papillomavirus infection with pegylated interferon and ribavirin.
abstract: We report a case of disseminated human papillomavirus infection that developed in a patient while receiving efalizumab for the treatment of psoriasis. This infection progressed for several months after efalizumab treatment had been stopped. All human papillomavirus lesions completely resolved after 10 weeks of therapy with a combination of pegylated interferon and ribavirin.
authors.affiliation: Department of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA. shrestn@ccf.org
authors.forename: Nabin K
authors.initials: NK
authors.lastname: Shrestha
authors.forename: David J
authors.initials: DJ
authors.lastname: Hamrock
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal / Q000009:adverse effects; D061067:Antibodies, Monoclonal, Humanized; D000998:Antiviral Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D008297:Male; D030361:Papillomavirus Infections / Q000188:drug therapy* / Q000209:etiology; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy; D012254:Ribavirin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons; C472181:efalizumab