Cardiac conductive disturbance in patients with polycystic ovary syndrome.
BACKGROUND
Polycystic ovary syndrome (PCOS) is the most common endocrine abnormality of reproductive-aged women and increases the risk of cardiovascular disease. However, the effects of PCOS on electrocardiograms (ECGs) are not fully elucidated. The aim of this study was to evaluate the characteristics of ECGs in patients with PCOS.


METHODS
This study included 24 patients with PCOS and 12 patients without PCOS. The heart rate, PR interval, QRS duration, Sokolow-Lyon voltage (SV1 + RV5/6), Cornell voltage (RaVL + SV3), QT interval and QTc interval were measured in 12-lead ECGs.


RESULTS
The QRS duration was wider in patients with PCOS than those without PCOS (91 ± 8 vs. 81 ± 10 ms, p < 0.05). The heart rate, PR interval, Sokolow-Lyon voltage, product of the QRS duration times Cornell voltage combination, QT interval, QTc interval, QT dispersion and QTc dispersion were similar between the two groups.


CONCLUSIONS
PCOS is associated with a widening QRS duration, which may contribute to its increased cardiovascular risks.
Huang
Jen-Hung
JH
Division of Cardiovascular Medicine, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan.
Tsai
Jen-Chen
JC
Hsu
Ming-I
MI
Chen
Yi-Jen
YJ
D000328:Adult; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D055815:Young Adult