Malignant transformation of monostotic fibrous dysplasia in the mandible.
Malignant transformation of fibrous dysplasia (FD), which was first introduced by Coley and Steward is very rare. We present a case of malignant transformation of monostotic mandibular FD after 2 surgical excisions, 20 and 15 years ago, respectively. The treatment choice of FD is usually conservative. With the advanced surgical techniques, radical excisions followed by immediate reconstruction have been reported. However, the decision criteria are still controversial and we might think that radical treatment is a good method for recurrent lesions based on the recent literatures. The case discussed here is of sarcomatous transformation of a recurrent FD.
Kim
Gyu-Tae
GT
Departments of Oral & Maxillofacial Radiology, Kyung Hee University Medical Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
Lee
Jung-Kyo
JK
Choi
Byung-Joon
BJ
Kim
Jin
J
Han
Sun-Hee
SH
Kwon
Yong-Dae
YD
D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D003287:Contrast Media; D005260:Female; D005358:Fibrous Dysplasia, Monostotic / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008336:Mandibular Diseases / Q000473:pathology* / Q000601:surgery; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012516:Osteosarcoma / Q000473:pathology* / Q000601:surgery; D011862:Radiography, Panoramic; D012008:Recurrence; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D005682:Gadolinium