FDG-PET is effective in the detection of granulocytic sarcoma in patients with myeloid malignancy.
Granulocytic sarcomas (GSs) are extramedullary tumors that consist of myeloid cells in patients with myeloid malignancies. The role for (18)F-fluorodeoxyglucose-positron-emission tomography (FDG-PET) to detect GSs has been unclear. We retrospectively evaluated seven patients with pathologically proven GSs. Compared with other diagnostic tools, FDG-PET was more effective or at least equivalent in the detection of GSs in six patients, but was less effective in one patient. Maximum standardized uptake value (SUVmax) for the lesions widely varied from 2.6 to 9.7. When our findings and previous reports taken together, FDG-PET is an effective tool to search for GSs, however, other diagnostic tools including computed tomography (CT) are still necessary to detect morphological abnormalities.
Ueda
Koki
K
Department of Hematology and Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Ichikawa
Motoshi
M
Takahashi
Miwako
M
Momose
Toshimitsu
T
Ohtomo
Kuni
K
Kurokawa
Mineo
M
D019046:Bone Marrow Neoplasms / Q000000981:diagnostic imaging*; D006098:Granulocytes; D006801:Humans; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D012189:Retrospective Studies; D012509:Sarcoma / Q000000981:diagnostic imaging*