[Dermatoendocrinology. Skin aging].
Hormones and their imbalances have significant effects on the morphology and physiology of the skin and influence various skin functions, especially wound healing and lipogenesis. With increasing age, the concentrations of important circulating hormones, including growth hormone and sex-related steroids, decrease continuously. As a result, physiologic processes are negatively influenced and various age-associated disorders may develop. As the population aged 80 and over is expected to rise in the next decades, the understanding of the molecular mechanisms accompanying skin aging and disease prevention will become even more important and play a role in preventing disease.
Makrantonaki
E
E
Klinik für Dermatologie, Venerologie und Allergologie/Immunologisches Zentrum, Städtisches Klinikum Dessau, Auenweg 38, 06847, Dessau, Germany. emakrantonaki@yahoo.com
Zouboulis
C C
CC
D000368:Aged; D000369:Aged, 80 and over; D047649:Andropause / Q000502:physiology; D002648:Child; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D020249:Hormone Replacement Therapy; D006728:Hormones / Q000097:blood*; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D008297:Male; D008593:Menopause / Q000502:physiology; D008875:Middle Aged; D011157:Population Dynamics; D011627:Puberty / Q000502:physiology; D012867:Skin / Q000473:pathology / Q000503:physiopathology; D015595:Skin Aging / Q000473:pathology / Q000502:physiology*; D012871:Skin Diseases / Q000473:pathology / Q000503:physiopathology*; D012878:Skin Neoplasms / Q000473:pathology / Q000503:physiopathology*
D012739:Gonadal Steroid Hormones; D006728:Hormones; D019382:Human Growth Hormone