Conversion of carbonyl compounds to alkynes: general overview and recent developments.
The preparation of alkynes from carbonyl compounds via a one-carbon homologation has become a very useful pathway for the synthesis of acetylenic compounds, both internal and terminal. This tutorial review provides an overview of the different methods available for this transformation, including their scope and limitations, recent developments and applications in total syntheses.
Habrant
Damien
D
Laboratory of Organic Chemistry, Aalto University School of Science and Technology, PO Box 16100, FIN-00076 Aalto, Finland.
Rauhala
Vesa
V
Koskinen
Ari M P
AM