title: Two-stage total aortic replacement for Loeys-Dietz syndrome.
abstract: Loeys-Dietz syndrome (LDS) is a recently described connective tissue disorder characterized by generalized arterial tortuosity and aggressive aortopathy that untreated leads to early death even at aortic dimensions as small as 4 cm. We report the case of a young man with LDS successfully treated for aortic root, arch, and thoracoabdominal pathology.
authors.affiliation: Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Duke University, Durham, North Carolina 27710, USA.
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Williams
authors.forename: Stephanie Burns
authors.initials: SB
authors.lastname: Wechsler
authors.forename: G Chad
authors.initials: GC
authors.lastname: Hughes
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000601:surgery*; D001011:Aorta / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D006801:Humans; D055947:Loeys-Dietz Syndrome / Q000601:surgery*; D008297:Male; D016896:Treatment Outcome