First detection of CTX-M and SHV extended-spectrum beta-lactamases in Escherichia coli urinary tract isolates from dogs and cats in the United States.
One hundred fifty canine and feline Escherichia coli isolates associated with urinary tract infections were screened for the presence of extended-spectrum beta-lactamase (ESBL) genes. Out of 60 isolates suspected to be ESBL positive based on antimicrobial susceptibility testing, 11 ESBLs were identified, including one SHV-12 gene, one CTX-M-14 gene, and nine CTX-M-15 genes. This study provides the first report of CTX-M- and SHV-type ESBLs in dogs and cats in the United States.
O'Keefe
Alexandra
A
Matthew J. Ryan Veterinary Hospital, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104-6010, USA.
Hutton
Tabitha A
TA
Schifferli
Dieter M
DM
Rankin
Shelley C
SC
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002371:Cat Diseases / Q000382:microbiology*; D002415:Cats; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D014481:United States; D014552:Urinary Tract Infections / Q000382:microbiology / Q000662:veterinary*; D001618:beta-Lactamases / Q000235:genetics*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; C456080:beta-lactamase CTX-M-14; C473109:beta-lactamase CTX-M-15; C107198:beta-lactamase SHV-12; D001618:beta-Lactamases