Features of Gastric Neoplasm Detected during the Screening Examination.
OBJECTIVE
Gastric cancer is the leading malignancy in Korea and early detection through the health screening seems to be important. The aims of this study were to investigate the features of gastric neoplasms detected during screening, and to figure out the risk factors of these lesions.


METHODS
From October 2003 to September 2005, subjects who visited Seoul National University Hospital Healthcare System Gangnam Center for health check-up were included in the study. The program included a questionnaire and tests including anti-Helicobacter pylori (H. pylori) antibody, esophagogastroduodenoscopy or double contrast upper gastrointestinal study. To figure out the risk factors, an age and gender-matched, four-fold sized control group was selected from the subjects.


RESULTS
Of 25, 432 subjects, 122 cases of gastric neoplasms were detected including 61 adenocarcinoma (45 early gastric cancers), 53 adenoma, 7 mucosa-associated lymphoid tissue lymphoma, and one metastatic cancer. There was no significant statistical difference in basal characteristics of the subjects between gastric adenocarcinoma and adenoma. When comparing with the control group those without gastric neoplasms, smoking history, family history of stomach cancer, and H. pylori seropositivity were found to be significant risk factors for gastric neoplasms. Metabolic syndrome was more prevalent in adenoma than in the control (p<0.05).


CONCLUSIONS
The health screening may be beneficial in early detection of gastric cancer. In addition, metabolic syndrome might be related with gastric adenoma.
Park
Min Jung
MJ
Seoul National University Hospital, Healthcare System Gangnam Center, Healthcare Research Institute, Seoul, Korea.
Kim
Dong Hee
DH
Lim
Seon Hee
SH
Yim
Jeong Yoon
JY
Kim
Young Sun
YS
Cho
Kyung Ran
KR
Kim
Chung Hyeon
CH
Jung
Hyun Chae
HC
Song
In Sung
IS
Kim
Sun Sin
SS
Yoon
Dae Hyun
DH
Shin
Chan Soo
CS
Cho
Sang-Heon
SH
Oh
Byung-Hee
BH
Lee
Dong Ho
DH