title: Influence of titanium implant surface characteristics on bone regeneration in dehiscence-type defects: an experimental study in dogs.
abstract: OBJECTIVE
  The aim of the present study was to compare bone regeneration in dehiscence-type defects at titanium implants with chemically modified sandblasted/acid-etched (modSLA) or dual acid-etched surfaces with a calcium phosphate nanometre particle modification (DCD/CaP).
  
  
  METHODS
  Buccal dehiscence-type defects were surgically created following implant site preparation in both the upper and the lower jaws of 12 fox hounds. Both types of implants were randomly allocated in a split-mouth design and left to heal in a submerged position for 2 and 8 weeks. Dissected blocks were processed for histomorphometrical analysis [e.g. new bone height (NBH), percentage of bone-to-implant contact (BIC), area of new bone fill (BF), and area of mineralized tissue (MT) within BF].
  
  
  RESULTS
  At 2 and 8 weeks, both groups revealed comparable mean BF (2.3+/-0.6 to 2.5+/-0.6 mm(2)versus 2.0+/-0.6 to 1.4+/-0.5 mm(2)) and MT (31.1+/-14.3-83.2+/-8.2%versus 38.9+/-15.9-84.4+/-6.3%) values. However, modSLA implants revealed significantly higher mean NBH (2.4+/-0.8 to 3.6+/-0.3 mm versus 0.9+/-0.8 to 1.8+/-1.4 mm) and BIC (53.3+/-11.3-79.5+/-6.6%versus 19.3+/-16.4-47.2+/-30.7%) values than DCD/CaP implants.
  
  
  CONCLUSIONS
  ModSLA implants may have a higher potential to support osseointegration in dehiscence-type defects than DCD/CaP implants.
authors.affiliation: Department of Oral Surgery, Westdeutsche Kieferklinik, Germany. frank.schwarz@med.uni-dueseldorf.de
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.forename: Martin
authors.initials: M
authors.lastname: Sager
authors.forename: Ines
authors.initials: I
authors.lastname: Kadelka
authors.forename: Daniel
authors.initials: D
authors.lastname: Ferrari
authors.forename: Jürgen
authors.initials: J
authors.lastname: Becker
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods*; D000818:Animals; D002130:Calcium Phosphates; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D004285:Dogs; D053758:Nanoparticles; D016348:Osseointegration; D011897:Random Allocation; D013499:Surface Properties; D013529:Surgical Wound Dehiscence; D014025:Titanium
chemical_list: D002130:Calcium Phosphates; D015921:Dental Implants; C020243:calcium phosphate; D014025:Titanium