title: Unhealthy aggression: intermittent explosive disorder and adverse physical health outcomes.
abstract: OBJECTIVE
  To examine the relationship between Intermittent Explosive Disorder (IED; a psychiatric diagnosis characterized by episodes of affective aggression) and adverse physical health outcomes.
  
  
  METHODS
  A large epidemiological sample drawn from the Collaborative Psychiatric Epidemiological Surveys (N = 10,366), was used to compare participants with a lifetime diagnosis of IED (n = 929) to those without any history of IED (n = 9,437) on demographic variables (age, education, gender, race) common risk factors (smoking status, body mass index, substance use disorders, past accident or injury requiring treatment, major depression) and the presence of 12 adverse health outcomes.
  
  
  METHODS
  History of heart attacks, coronary heart disease, hypertension, stroke, lung disease, diabetes, cancer, arthritis, back/neck pain, ulcer, headaches, and other chronic pain.
  
  
  RESULTS
  Logistic regression analysis controlling for demographic and other risk factors indicated that IED was associated with 9 of the 12 adverse physical health outcomes (coronary heart disease, hypertension, stroke, diabetes, arthritis, back/neck pain, ulcer, headaches, and other chronic pain). Only cancer, heart attacks, and lung disease were not significantly related to IED.
  
  
  CONCLUSIONS
  IED may be a risk factor for several significant adverse physical health outcomes.
authors.affiliation: Department of Psychology, Temple University, 1701 North 13th Street, Philadelphia, PA 19122, USA. mikemccloskey@temple.edu
authors.forename: Michael S
authors.initials: MS
authors.lastname: McCloskey
authors.forename: Krystal
authors.initials: K
authors.lastname: Kleabir
authors.forename: Mitchell E
authors.initials: ME
authors.lastname: Berman
authors.forename: Eunice Y
authors.initials: EY
authors.lastname: Chen
authors.forename: Emil F
authors.initials: EF
authors.lastname: Coccaro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000374:Aggression / Q000523:psychology*; D015992:Body Mass Index; D016022:Case-Control Studies; D015897:Comorbidity; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011581:Psychological Tests; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult