Multiple drug resistance and strength of attachment to surfaces in Pseudomonas aeruginosa isolates.
OBJECTIVE
To investigate the presence of a relationship between the strength of attachment of Pseudomonas aeruginosa to stainless steel surfaces and their observed multiple drug resistance.


RESULTS
Multiple drug resistance of clinical and environmental isolates of Ps. aeruginosa was evaluated using disc diffusion method. The blot succession technique was used to quantify the strength of attachment of Ps. aeruginosa isolates. Different multiple drug-resistant Ps. aeruginosa isolates exhibited variable attachment strength. Although the highest multiple drug-resistant clinical isolate was shown to have the least attachment strength among clinical isolates, a weak correlation was found between attachment strength and multiple resistance among our investigated Ps. aeruginosa isolates.


CONCLUSIONS
There is a weak correlation between multiple drug resistance and strength of attachment to stainless steel surfaces.


CONCLUSIONS
Even low-resistant Ps. aeruginosa could have the potential of attaching firmly to surfaces and forming biofilm.
Haddadin
R N
RN
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Jordan, Amman, Jordan.
Saleh
S A
SA
Mahmoud
R A
RA
Shehabi
A A
AA
D001422:Bacterial Adhesion; D024901:Drug Resistance, Multiple, Bacterial; D004783:Environmental Microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification / Q000502:physiology*; D013193:Stainless Steel
D013193:Stainless Steel