title: Scalp reconstruction: regeneration with acellular dermal matrix.
abstract: BACKGROUND
  Current methods of scalp reconstruction with complicating osteomyelitis of underlying bone require excision of deficient tissue and a staged reconstruction for ultimate coverage of the defect. Our group proposes a novel use of acellular dermal matrix (ADM) to preserve these deficient areas without the need for excision or staged management of osteomyelitic calvaria.
  
  
  RESULTS
  From 2003 to 2008, 3 patients underwent scalp reconstruction with ADM at our facility. Elevation of the scalp for secondary operations in each case showed full incorporation of the ADM. Follow-up ranging from 12 to 36 months showed a healed scalp with preserved hair-bearing skin in all cases.
  
  
  CONCLUSIONS
  Scalp regeneration with ADM has specific advantages that include preservation of hair-bearing scalp, maintenance of distinct tissue planes for later reconstruction, absence of a donor site, and the alleviation of tissue expansion. This technology may represent an immediate solution for difficult scalp defects that would otherwise require staged complex reconstruction.
authors.affiliation: Division of Pediatric Plastic Surgery, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Kinsella
authors.forename: Lorelei J
authors.initials: LJ
authors.lastname: Grunwaldt
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Cooper
authors.forename: Mimi Chao
authors.initials: MC
authors.lastname: Mills
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Losee
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use*; D016025:Bone Transplantation; D002648:Child; D003094:Collagen / Q000627:therapeutic use*; D003399:Craniotomy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D012038:Regeneration / Q000502:physiology; D012535:Scalp / Q000601:surgery*; D017768:Skin, Artificial; D012886:Skull / Q000601:surgery; D013524:Surgical Flaps; D013529:Surgical Wound Dehiscence / Q000601:surgery; D013530:Surgical Wound Infection / Q000601:surgery; D016896:Treatment Outcome
chemical_list: C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen