title: A summary of computational resources for protein phosphorylation.
abstract: Protein phosphorylation is the most ubiquitous post-translational modification (PTM), and plays important roles in most of biological processes. Identification of site-specific phosphorylated substrates is fundamental for understanding the molecular mechanisms of phosphorylation. Besides experimental approaches, prediction of potential candidates with computational methods has also attracted great attention for its convenience, fast-speed and low-cost. In this review, we present a comprehensive but brief summarization of computational resources of protein phosphorylation, including phosphorylation databases, prediction of non-specific or organism-specific phosphorylation sites, prediction of kinase-specific phosphorylation sites or phospho-binding motifs, and other tools. The latest compendium of computational resources for protein phosphorylation is available at: http://gps.biocuckoo.org/links.php.
authors.affiliation: Hubei Bioinformatics and Molecular Imaging Key Laboratory, Department of Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China. xueyu@mail.hust.edu.cn
authors.forename: Yu
authors.initials: Y
authors.lastname: Xue
authors.forename: Xinjiao
authors.initials: X
authors.lastname: Gao
authors.forename: Jun
authors.initials: J
authors.lastname: Cao
authors.forename: Zexian
authors.initials: Z
authors.lastname: Liu
authors.forename: Changjiang
authors.initials: C
authors.lastname: Jin
authors.forename: Longping
authors.initials: L
authors.lastname: Wen
authors.forename: Xuebiao
authors.initials: X
authors.lastname: Yao
authors.forename: Jian
authors.initials: J
authors.lastname: Ren
mesh_terms: D000465:Algorithms; D001665:Binding Sites; D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D020407:Internet; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D012984:Software
chemical_list: D011506:Proteins; D011494:Protein Kinases