title: Asymptomatic somatostatinoma of the pancreatic head: Report of a case.
abstract: A 44-year-old man was attending routine follow-up 5 years after colon cancer resection, when ultrasonography detected a pancreatic tumor with a low echoic area. He had no symptoms. Computed tomography (CT) showed a protruding-type tumor, 4 cm in diameter, in the pancreatic head with central necrosis. Angiography revealed that the tumor was hypervascular. The serum somatostatin level was elevated, at 27 pg/ml (normal range, 1.0-12 pg/ml). As somatostatinoma of the pancreas was suspected, we performed pylorus-preserving pancreaticoduodenectomy. Histological and immunohistochemical staining confirmed somatostatinoma of the pancreas without nodal metastasis. Thus, if an endocrine tumor of the pancreas is suspected in a patient with a hypervascular tumor, the possibility of somatostatinoma should be included in the differential diagnosis.
authors.affiliation: Department of Surgical Oncology and Digestive Surgery, Field of Oncology, Course of Advanced Therapeutics, Kagoshima University School of Medical and Dental Science, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Arima
authors.forename: Shoji
authors.initials: S
authors.lastname: Natsugoe
authors.forename: Kousei
authors.initials: K
authors.lastname: Maemura
authors.forename: Youichi
authors.initials: Y
authors.lastname: Hata
authors.forename: Toru
authors.initials: T
authors.lastname: Kumanohoso
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Yuko
authors.initials: Y
authors.lastname: Mataki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kurahara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shinchi
authors.forename: Sonshin
authors.initials: S
authors.lastname: Takao
authors.forename: Takashi
authors.initials: T
authors.lastname: Aikou
mesh_terms: D000328:Adult; D003110:Colonic Neoplasms / Q000601:surgery; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D016577:Pancreaticoduodenectomy; D013004:Somatostatin / Q000097:blood*; D013005:Somatostatinoma / Q000097:blood / Q000175:diagnosis*
chemical_list: D013004:Somatostatin