title: Photoaffinity labeling of benzodiazepine-receptors: Possible mechanism of reaction.
abstract: Photoaffinity labeling of brain benzodiazepine-receptors with [(3)H]flunitrazepam ([(3)H]FNZ) results in the covalent linking of the ligand to [(3)H]FNZ-binding site. The major findings in benzodiazepine-receptor studies employing photoaffinity labeling are described; the covalent linking of [(3)H]FNZ is compared to its reversible binding; and a mechanism for the labeling reaction is postulated.
authors.affiliation: Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Sherman-Gold