LC-MS-SPE-NMR for the isolation and characterization of neo-clerodane diterpenoids from Teucrium luteum subsp. flavovirens (perpendicular).
neo-Clerodane diterpenes of plant origin are molecules difficult to monitor due to their nonspecific UV/vis absorption. The present work describes for the first time the application of the LC-MS-SPE-NMR technique for the isolation and characterization of three new neo-clerodane diterpenes, 3beta-hydroxyteucroxylepin and teuluteumin A and teuluteumin B, from Teucrium luteum subsp. flavovirens, harvested from two different locations.
Castro
Amaya
A
Institut de Quimica Avancada de Catalunya, Consejo Superior de Investigaciones Cientificas, Barcelona, Spain.
Moco
Sofia
S
Coll
Josep
J
Vervoort
Jacques
J
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D009018:Morocco; D019906:Nuclear Magnetic Resonance, Biomolecular; D013056:Spectrophotometry, Ultraviolet; D031367:Teucrium / Q000737:chemistry
C550040:3beta-hydroxyteucroxylepin; D004224:Diterpenes; D045785:Diterpenes, Clerodane; C550041:teuluteumin A; C550042:teuluteumin B