title: Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: a case report.
abstract: OBJECTIVE
  To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disccuss the ante-, peri- and postpartum management.
  
  
  METHODS
  A case report and review of the literature.
  
  
  RESULTS
  FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was successfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and referred to hematology department for further follow-up.
  
  
  CONCLUSIONS
  FVIID, a rare cause of ante- and postpartum hemorrhages that may differently present by other hemorrhages (i.e.: epistaxis), can be optimally managed with replacement of rFVII.
authors.affiliation: Ankara University School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey. gaynaoglu@gmail.com
authors.forename: Gülşah
authors.initials: G
authors.lastname: Aynaoğlu
authors.forename: Gülşen Doğan
authors.initials: GD
authors.lastname: Durdağ
authors.forename: Batuhan
authors.initials: B
authors.lastname: Ozmen
authors.forename: Feride
authors.initials: F
authors.lastname: Söylemez
mesh_terms: D004844:Epistaxis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D005167:Factor VII / Q000627:therapeutic use; D005168:Factor VII Deficiency / Q000150:complications / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D011994:Recombinant Proteins; D005167:Factor VII