title: Angiosarcoma following MammoSite partial breast irradiation.
abstract: Angiosarcoma is a rare tumor of endothelial origin which commonly arises in small blood or lymphatic vessels. Its development in the treated breast following adjuvant external beam radiation is also rare. To our knowledge, there are no reported cases in the literature or MammoSite registry which describe the occurrence of angiosarcoma in the treated breast following MammoSite brachytherapy. This is a case report of a 74 year old female who developed angiosarcoma 4 years after receiving MammoSite balloon brachytherapy following surgical resection of a T1mic N0 M0 infiltrating ductal carcinoma.
authors.affiliation: Department of Radiation Oncology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Andrews
authors.forename: Rebecca
authors.initials: R
authors.lastname: Wilcoxon
authors.forename: Jo
authors.initials: J
authors.lastname: Benda
authors.forename: Geraldine
authors.initials: G
authors.lastname: Jacobson
mesh_terms: D000368:Aged; D001706:Biopsy; D001918:Brachytherapy / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D019583:Dose Fractionation, Radiation; D005260:Female; D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D018714:Radiotherapy, Adjuvant