title: Pulmonary tuberculosis due to Mycobacterium microti: a study of six recent cases in France.
abstract: Human tuberculosis caused by Mycobacterium microti is rare, but its prevalence and clinical significance may have been underestimated. To the best of our knowledge, 21 cases have been reported in the literature in the last decade. We report six recent pulmonary cases caused by M. microti over a period of 5 years detected in French clinical mycobacteriology laboratories of the hospital network. Our data confirm the potential of M. microti to cause clinical illness in immunocompetent patients. M. microti grew slowly from specimens, delaying the final microbiological diagnosis. Therefore, patients with tuberculosis caused by M. microti could benefit from the use of rapid diagnostic molecular techniques directly on clinical samples. From a review of the literature and this study, a classical antituberculous therapy seems effective in treating patients with M. microti disease.
authors.affiliation: Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
authors.forename: G
authors.initials: G
authors.lastname: Panteix
authors.affiliation: Institut Pasteur de Lille, INSERM U629, 1 Rue du Professeur Calmette, 59021 Lille, France.
authors.forename: M C
authors.initials: MC
authors.lastname: Gutierrez
authors.affiliation: Unité Zoonoses Bactériennes, Agence Française de Sécurité Sanitaire des Aliments, 23 Avenue du Général de Gaulle, 94706 Maisons-Alfort Cedex, France.
authors.forename: M L
authors.initials: ML
authors.lastname: Boschiroli
authors.affiliation: Laboratoire de Biologie, Centre Hospitalier Général Gui de Chauliac de Mende, Avenue du 8 Mai 1945, BP 10, 48010 Mende Cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Rouviere
authors.affiliation: Laboratoire de Biologie, Centre Hospitalier de Vichy, Boulevard Deniere, BP 2757, 03207 Vichy Cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Plaidy
authors.affiliation: Laboratoire de Biologie, Centre Hospitalier de Tulle, 3 Place Maschat, BP 160, 19012 Tulle Cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Pressac
authors.affiliation: Laboratoire de Biologie, Centre Hospitalier Robert Ballanger (CHRB), 93602 Aulnay-Sous-Bois Cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Porcheret
authors.affiliation: Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
authors.forename: G
authors.initials: G
authors.lastname: Chyderiotis
authors.affiliation: Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Ponsada
authors.affiliation: Service de Pneumologie, Centre Hospitalier Général Gui de Chauliac de Mende, Avenue du 8 Mai 1945, BP 10, 48010 Mende Cedex, France.
authors.forename: K
authors.initials: K
authors.lastname: Van Oortegem
authors.affiliation: Service de Pneumologie, Centre Hospitalier de Vendome, 41106 Vendome Cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Salloum
authors.affiliation: Service de Médecine Interne et Pneumologie, Centre Hospitalier d'Aubenas, 9 Chemin de Bois Vignal, BP 146, 07205 Aubenas, France.
authors.forename: S
authors.initials: S
authors.lastname: Cabuzel
authors.affiliation: GEMI, UMR CNRS-IRD 2724, Centre IRD de Montpellier, France.
authors.forename: A L
authors.initials: AL
authors.lastname: Bañuls
authors.affiliation: Université Montpellier 1, EA 4205 'Transmission, Pathogenèse et Prévention de l'Infection par le VIH', and Laboratoire de Bactériologie-Virologie Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, F-34295 Montpellier Cedex 5, France.
authors.forename: P
authors.initials: P
authors.lastname: Van de Perre
authors.affiliation: Université Montpellier 1, EA 4205 'Transmission, Pathogenèse et Prévention de l'Infection par le VIH', and Laboratoire de Bactériologie-Virologie Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, F-34295 Montpellier Cedex 5, France.|GEMI, UMR CNRS-IRD 2724, Centre IRD de Montpellier, France.
authors.forename: S
authors.initials: S
authors.lastname: Godreuil
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents