title: Diastereoselective encapsulation of tartaric acid by a helical aromatic oligoamide.
abstract: A helical aromatic oligoamide foldamer encapsulates tartaric acid with exceptional affinity, selectivity, and diastereoselectivity. The structure of the complex has been elucidated both in solution by NMR spectroscopy and in the solid state by X-ray crystallography, making it possible to rationalize the strong effects observed, particularly the role of hydrogen bonds between the hydroxyl and carboxylic acid groups of tartaric acid and the inner wall of the helically folded capsule, which completely surrounds the guest and insulates it from the solvent.
authors.affiliation: Institut Européen de Chimie et Biologie, Université de Bordeaux-CNRS UMR5248 and UMS3033, 2 rue Robert Escarpit, 33607 Pessac, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Ferrand
authors.forename: Amol M
authors.initials: AM
authors.lastname: Kendhale
authors.forename: Brice
authors.initials: B
authors.lastname: Kauffmann
authors.forename: Axelle
authors.initials: A
authors.lastname: Grélard
authors.forename: Cécile
authors.initials: C
authors.lastname: Marie
authors.forename: Virginie
authors.initials: V
authors.lastname: Blot
authors.forename: Muriel
authors.initials: M
authors.lastname: Pipelier
authors.forename: Didier
authors.initials: D
authors.lastname: Dubreuil
authors.forename: Ivan
authors.initials: I
authors.lastname: Huc