title: [Eosinophilic fasciitis (Shulman's disease): a case series of 11 patients].
abstract: OBJECTIVE
  Eosinophilic fasciitis or Shulman's disease is a rare condition of unknown etiology.
  
  
  METHODS
  We report a retrospective case series of 11 patients with eosinophilic fasciitis (seven men and four women, including a single pediatric case) and perform a systematic literature review to determine the main features of this disease.
  
  
  RESULTS
  Mean age of the patients was 46 years. Subcutaneous induration of limbs observed in all the patients was the major presenting symptom. The induration was atypically located in the chest area in two patients. Blood eosinophilia was absent in five cases. Histological fasciitis was demonstrated in all patients and eosinophilic infiltration was present in seven patients. Relapse of subcutaneous induration was observed in only one patient who gradually developed systemic sclerosis.
  
  
  CONCLUSIONS
  Diagnosis of eosinophilic fasciitis should be considered in the presence myalgia and subcutaneous induration of limbs, blood eosinophilia and hypergammaglobulinemia. Treatment is based on systemic corticosteroids.
authors.affiliation: Service de médecine interne, hôpital Mongi Slim, La Marsa, Tunisia. naouitn2001@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Naoui
authors.forename: K
authors.initials: K
authors.lastname: Bouslama
authors.forename: M
authors.initials: M
authors.lastname: Abdallah
authors.forename: S
authors.initials: S
authors.lastname: Hamzaoui
authors.forename: T
authors.initials: T
authors.lastname: Arbi
authors.forename: F
authors.initials: F
authors.lastname: Bahri
authors.forename: S
authors.initials: S
authors.lastname: M'zabi
authors.forename: A
authors.initials: A
authors.lastname: Harmel
authors.forename: M
authors.initials: M
authors.lastname: Ennafaa
authors.forename: M
authors.initials: M
authors.lastname: Ben Dridi
authors.forename: S
authors.initials: S
authors.lastname: M'rad
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis*; D005208:Fasciitis / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies