GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.
CONCLUSIONS
Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.


METHODS
The GPCR-OKB web application is freely available at http://www.gpcr-okb.org
Khelashvili
George
G
Department of Physiology & Biophysics, Weill Medical College of Cornell University, New York, NY, USA.
Dorff
Kevin
K
Shan
Jufang
J
Camacho-Artacho
Marta
M
Skrabanek
Lucy
L
Vroling
Bas
B
Bouvier
Michel
M
Devi
Lakshmi A
LA
George
Susan R
SR
Javitch
Jonathan A
JA
Lohse
Martin J
MJ
Milligan
Graeme
G
Neubig
Richard R
RR
Palczewski
Krzysztof
K
Parmentier
Marc
M
Pin
Jean-Philippe
JP
Vriend
Gerrit
G
Campagne
Fabien
F
Filizola
Marta
M
D016208:Databases, Factual; D020407:Internet; D051188:Knowledge Bases; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry*; D012984:Software
D043562:Receptors, G-Protein-Coupled