title: Can morels (Morchella sp.) induce a toxic neurological syndrome?
abstract: BACKGROUND
  Several cases of morel poisoning associated with neurological symptoms have been reported. The objective of this study was to describe this new mushroom poisoning syndrome.
  
  
  METHODS
  Retrospective study of morel poisonings collected in the French Poison Control Centers from 1976 to 2006. Cases were classified as neurological syndrome (NS; tremor or dizziness/inebriation or unsteadiness/ataxia +/- associated with gastrointestinal symptoms) or isolated gastrointestinal syndrome.
  
  
  RESULTS
  146 patients presented gastrointestinal syndrome (median time to onset: 5 h) and 129 presented NS (12 h) after morel consumption. Gastrointestinal (67%) and other neurological symptoms were also present (mainly ocular/vision disorders: 26%, paresthesia: 7%, drowsiness/confusion: 6%, and muscle disorders: 6%). These patients more frequently ingested a large quantity of morels. Confusion with Gyromitra was ruled out.
  
  
  CONCLUSIONS
  The NS is very different from the common gastrointestinal syndrome occurring after ingestion of poorly cooked morels and is not limited to a cerebellar syndrome.
authors.affiliation: Toxicovigilance Center, Michallon Hospital, Grenoble, France. PSaviuc@chu-grenoble.fr <PSaviuc@chu-grenoble.fr>
authors.forename: Philippe
authors.initials: P
authors.lastname: Saviuc
authors.forename: Patrick
authors.initials: P
authors.lastname: Harry
authors.forename: Corine
authors.initials: C
authors.lastname: Pulce
authors.forename: Robert
authors.initials: R
authors.lastname: Garnier
authors.forename: Amandine
authors.initials: A
authors.lastname: Cochet
mesh_terms: D000328:Adult; D001203:Ascomycota; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000175:diagnosis / Q000453:epidemiology*; D009183:Mycotoxins / Q000633:toxicity*; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000453:epidemiology; D012189:Retrospective Studies; D013577:Syndrome
chemical_list: D009183:Mycotoxins