title: Lanarkshire Oximetry Index as a diagnostic tool for peripheral arterial disease in type 2 diabetes: a pilot study.
abstract: We evaluated the Lanarkshire Oximetry Index (LOI) for the diagnosis of peripheral arterial disease (PAD) in type 2 diabetic patients, using the Ankle-Brachial Index (ABI) as gold standard. We included 161 patients (71 men, mean age 63.1 +/- 9.8 years). Peripheral arterial disease was defined as ABI < 0.9. Two cut-off values of LOI (<0.9 and <0.8) were assessed for the diagnosis of PAD. Sensitivity and specificity for PAD were 93.3% and 89.1%, respectively, using a LOI cut-off value of 0.9, while they were 40% and 99.3%, respectively, using a LOI cut-off value of 0.8. Agreement between LOI and ABI was moderate (P < .001). There was a significant positive correlation between ABI and LOI (r = .377, P < .001). Lanarkshire Oximetry Index is a potentially useful alternative diagnostic test for PAD in type 2 diabetes. A cut-off value of 0.9 has high sensitivity and modest specificity. Agreement between LOI and ABI is moderate.
authors.affiliation: Outpatient Clinic of the Diabetic Foot in the Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece. papanasnikos@yahoo.gr
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Papanas
authors.forename: D
authors.initials: D
authors.lastname: Kakagia
authors.forename: K
authors.initials: K
authors.lastname: Papatheodorou
authors.forename: D
authors.initials: D
authors.lastname: Papazoglou
authors.forename: M
authors.initials: M
authors.lastname: Alexandridou
authors.forename: A
authors.initials: A
authors.lastname: Pagkalos
authors.forename: E J
authors.initials: EJ
authors.lastname: Karadimas
authors.forename: E
authors.initials: E
authors.lastname: Maltezos
mesh_terms: D000368:Aged; D055109:Ankle Brachial Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000379:methods*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism; D010865:Pilot Projects; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012307:Risk Factors