Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.
Phytoceuticals (non-nutritional but beneficial plant chemicals) merit investigation as pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD). Although asthma is mostly treated adequately, COPD is not. Thus, there is a need for new drugs with improved therapeutic benefit, especially in COPD. Recent interest in herbal remedies has redirected attention towards plants as sources of improved treatments for lung disease. Phytoceuticals from a variety of plants and plant products, including butterbur, English ivy, apples, chocolate, green tea and red wine, demonstrate broad-spectrum pharmacotherapeutic activities that could be exploited in the clinic. Well-designed clinical trials are required to determine whether these beneficial activities are reproduced in patients, with the prospect that phytoceuticals are the new physic garden for asthma and COPD.
Grandhi
Sumalatha
S
Airway Disease, National Heart & Lung Institute, Imperial College London, Dovehouse Street, London SW3 6LY, UK.
Donnelly
Louise E
LE
Rogers
Duncan F
DF