title: HPLC and TLC enantioseparation of the nitro-positioned aryloxysubstituted aminopropanols.
abstract: An enantioseparation study of nitro-substituted aryloxyaminopropanols was performed using HPLC on a teicoplanin chiral stationary phase and TLC impregnated with L-aspartic and L-tartaric acid as chiral selectors. The type of substituent on the nitrogen in the hydrophilic part of molecule is essential for excellent separation by HPLC. L-aspartic acid seems to be a suitable chiral selector for enantioseparation by TLC.
authors.affiliation: Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic. cizmarikova@fpharm.uniba.sk
authors.forename: R
authors.initials: R
authors.lastname: Cizmáriková
authors.forename: K
authors.initials: K
authors.lastname: Bruchatá
authors.forename: Z
authors.initials: Z
authors.lastname: Pastírová
authors.forename: J
authors.initials: J
authors.lastname: Lehotay
authors.forename: K
authors.initials: K
authors.lastname: Hrobonová
mesh_terms: D001224:Aspartic Acid / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D007202:Indicators and Reagents; D009574:Nitro Compounds / Q000737:chemistry*; D011412:Propanolamines / Q000737:chemistry*; D013237:Stereoisomerism; D013644:Tartrates / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D009574:Nitro Compounds; D011412:Propanolamines; D013644:Tartrates; D001224:Aspartic Acid; C029768:tartaric acid