DIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS.
We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional 'progressive' approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary sequence information to construct multiple protein alignments. Both programs are available through 'Göttingen Bioinformatics Compute Server' (GOBICS).
Subramanian
Amarendran R
AR
Wilhelm-Schickard-Institut für Informatik, University of Tübingen, Sand 13, 72076 Tübingen, Germany.
Hiran
Suvrat
S
Steinkamp
Rasmus
R
Meinicke
Peter
P
Corel
Eduardo
E
Morgenstern
Burkhard
B
D020407:Internet; D017433:Protein Structure, Secondary; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein; D012984:Software