Do different populations of GABA-receptors exist in the vertebrate CNS?
Studies of the possible multiplicity of GABA-receptors that have been conducted with ligand-binding techniques and with certain electrophysiological and behavioral methods have been reviewed and analyzed. It seems evident that different populations of GABA binding sites exist in subcellular preparations of CNS tissues, but it is not yet certain that these sites reflect different populations of GABA-receptors that might exist in vivo.
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