Exercise-induced asthma in children.
Exercise-induced bronchoconstriction affects 40-90% of people with asthma, compared with 3-15% of the general population. Exercise-induced asthma (EIA) is diagnosed on the basis of subjective symptoms of airflow obstruction during and after exercise, objective measures of airflow obstruction and the exclusion of alternative diagnoses. Although the pathogenesis of EIA has not been fully elucidated, two major theories have been proposed: the airway rewarming theory and the hyperosmolarity theory. Increasing evidence suggests that airway inflammation plays a major role in the pathogenesis of EIA. In this article, we review the prevalence, pathogenesis, methods for diagnosis and treatment of EIA, as well as the responsiveness of children and adolescents to EIA therapies.
Lee
So-Yeon
SY
Department of Pediatrics, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Youngdeungpo-dong, Youngdeungpo-gu, Seoul, Korea. imipenem@hanmail.net
Kim
Hyo-Bin
HB
Yu
Jinho
J
Hong
Soo-Jong
SJ