title: Features of Gastric Neoplasm Detected during the Screening Examination.
abstract: OBJECTIVE
  Gastric cancer is the leading malignancy in Korea and early detection through the health screening seems to be important. The aims of this study were to investigate the features of gastric neoplasms detected during screening, and to figure out the risk factors of these lesions.
  
  
  METHODS
  From October 2003 to September 2005, subjects who visited Seoul National University Hospital Healthcare System Gangnam Center for health check-up were included in the study. The program included a questionnaire and tests including anti-Helicobacter pylori (H. pylori) antibody, esophagogastroduodenoscopy or double contrast upper gastrointestinal study. To figure out the risk factors, an age and gender-matched, four-fold sized control group was selected from the subjects.
  
  
  RESULTS
  Of 25, 432 subjects, 122 cases of gastric neoplasms were detected including 61 adenocarcinoma (45 early gastric cancers), 53 adenoma, 7 mucosa-associated lymphoid tissue lymphoma, and one metastatic cancer. There was no significant statistical difference in basal characteristics of the subjects between gastric adenocarcinoma and adenoma. When comparing with the control group those without gastric neoplasms, smoking history, family history of stomach cancer, and H. pylori seropositivity were found to be significant risk factors for gastric neoplasms. Metabolic syndrome was more prevalent in adenoma than in the control (p<0.05).
  
  
  CONCLUSIONS
  The health screening may be beneficial in early detection of gastric cancer. In addition, metabolic syndrome might be related with gastric adenoma.
authors.affiliation: Seoul National University Hospital, Healthcare System Gangnam Center, Healthcare Research Institute, Seoul, Korea.
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Park
authors.forename: Dong Hee
authors.initials: DH
authors.lastname: Kim
authors.forename: Seon Hee
authors.initials: SH
authors.lastname: Lim
authors.forename: Jeong Yoon
authors.initials: JY
authors.lastname: Yim
authors.forename: Young Sun
authors.initials: YS
authors.lastname: Kim
authors.forename: Kyung Ran
authors.initials: KR
authors.lastname: Cho
authors.forename: Chung Hyeon
authors.initials: CH
authors.lastname: Kim
authors.forename: Hyun Chae
authors.initials: HC
authors.lastname: Jung
authors.forename: In Sung
authors.initials: IS
authors.lastname: Song
authors.forename: Sun Sin
authors.initials: SS
authors.lastname: Kim
authors.forename: Dae Hyun
authors.initials: DH
authors.lastname: Yoon
authors.forename: Chan Soo
authors.initials: CS
authors.lastname: Shin
authors.forename: Sang-Heon
authors.initials: SH
authors.lastname: Cho
authors.forename: Byung-Hee
authors.initials: BH
authors.lastname: Oh
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Lee