title: A new approach to accelerate orthodontic tooth movement in women: Orthodontic force application after ovulation.
abstract: Tooth movement occurs as a consequence of periodontal tissue remodeling. The goal of every orthodontist is to investigate better approaches to accelerate tooth movement. Estrogen, by binding with its receptors in periodontal tissue, regulates the remodeling of alveolar bones, promotes bone formation, and inhibits bone resorption. Estrogen secretion in vivo is characterized by a nearly lunar rhythm. The estrogen expression level is low during menstruation and the luteal phase, and reaches the highest at 1-2days before ovulation. Estrogen physiological fluctuations can cause physiological fluctuations in the serum markers of bone turnover. Therefore, orthodontic therapy should be planned according to the menstrual cycle since tooth movement, under the application of force, is faster during low estrogen levels. In this paper, we propose a hypothesis that application of orthodontic force after each ovulation may promote tooth movement, thereby shortening the course of orthodontic treatment.
authors.affiliation: Department of Orthodontics, West China Hospital of Stomatology, State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, Sichuan, PR China.
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Xu
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhao
authors.forename: Siwei
authors.initials: S
authors.lastname: Yang
authors.forename: Guangxin
authors.initials: G
authors.lastname: Fu
authors.forename: Yangxi
authors.initials: Y
authors.lastname: Chen
mesh_terms: D016723:Bone Remodeling / Q000502:physiology*; D004967:Estrogens / Q000378:metabolism* / Q000502:physiology; D005260:Female; D006801:Humans; D009971:Orthodontics, Corrective / Q000379:methods*; D010060:Ovulation / Q000502:physiology*; D013997:Time Factors; D014086:Tooth Mobility / Q000503:physiopathology*; D014087:Tooth Movement Techniques / Q000379:methods*
chemical_list: D004967:Estrogens