title: Mitochondrial DNA polymorphisms in Gelao ethnic group residing in Southwest China.
abstract: Gelao ethnic group, an aboriginal population residing in southwest China, has undergone a long and complex evolutionary process. To investigate the genetic structure of this ancient ethnic group, mitochondrial DNA (mtDNA) polymorphisms of 102 Gelao individuals were collected and analyzed in this study. With the aid of the information extracted from control-region hypervariable segments (HVSs) I and II as well as some necessary coding-region segments, phylogenetic status of all mtDNAs under study were determined by means of classifying into various defined haplogroups. The southern-prevalent haplogroups B, R9, and M7 account for 45.1% of the gene pool, whereas northern-prevalent haplogroups A, D, G, N9, and M8 consist of 39.2%. Haplogroup distribution indicates that the Gelao bears signatures of southern populations and possesses some regional characters. In the PC map, Gelao clusters together with populations with Bai-Yue tribe origin as well as the local Han and the Miao. The results demonstrate the complexity of Gelao population and the data can well supplement the China mtDNA database.
authors.affiliation: Shenzhen People's Hospital, Clinical Medical College of Jinan University, Shenzhen, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Sha-Yan
authors.initials: SY
authors.lastname: Wang
authors.forename: Mian
authors.initials: M
authors.lastname: Zhao
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Xu
authors.forename: Yu-Hua
authors.initials: YH
authors.lastname: Hu
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Ruan-Zhang
authors.initials: RZ
authors.lastname: Zhang
authors.forename: Guo-Feng
authors.initials: GF
authors.lastname: Gao
authors.forename: Yue-Sheng
authors.initials: YS
authors.lastname: Yu
authors.forename: Qing-Peng
authors.initials: QP
authors.lastname: Kong
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China; D022801:Complementarity Determining Regions / Q000235:genetics; D016172:DNA Fingerprinting; D004272:DNA, Mitochondrial / Q000235:genetics*; D016208:Databases, Factual; D005006:Ethnicity / Q000235:genetics*; D005788:Gene Pool; D014644:Genetic Variation; D005828:Genetics, Population; D005843:Geography; D006239:Haplotypes; D006801:Humans; D008928:Mitochondria / Q000235:genetics; D016366:Open Reading Frames; D010802:Phylogeny; D011110:Polymorphism, Genetic; D012015:Reference Standards
chemical_list: D022801:Complementarity Determining Regions; D004272:DNA, Mitochondrial