[Experimental investigation of antiinflammatory and anesthetic properties of calcium pectate].
Antiinflammatory (antiexudative, antiproliferative) activity of calcium pectate was revealed by tests on the mice leg carrageenan-induced edema and cotton-ball granuloma models. It was also established that this polysaccharide produced an anesthetic effect comparable with that of indomethacin on the model of acetate-induced convulsions in mice.
Efimova
L A
LA
Krylova
S G
SG
Zueva
E P
EP
Khotimchenko
Iu S
IuS
Khotimchenko
M Iu
MIu
D000777:Anesthetics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002351:Carrageenan / Q000633:toxicity; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy*; D005260:Female; D006099:Granuloma / Q000139:chemically induced / Q000188:drug therapy*; D007213:Indomethacin / Q000494:pharmacology; D051379:Mice; D010368:Pectins / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D000777:Anesthetics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010368:Pectins; D002351:Carrageenan; C003181:polygalacturonic acid; D007213:Indomethacin