title: Flaxseed, olive and fish oil influence plasmatic lipids, lymphocyte migration and morphometry of the intestinal of Wistar rats.
abstract: OBJECTIVE
  Evaluate the effect of flaxseed, olive and fish oil on the lipid profile, preservation of villosities and lymphocyte migration in the intestinal mucosa of Wistar rats.
  
  
  METHODS
  Thirty Wistar male rats were divided into four groups, which received the AIN-93M diet, with changes only to their lipid source: flaxseed, olive, fish, and soy oil (control group). The serum was separated for the biochemical parameter analysis. A histological evaluation was performed in the ileal portion.
  
  
  RESULTS
  The group which was fed fish oil presented lower values when compared to the other treatments for Total Cholesterol, High-density Lipoprotein Cholesterol and Triacylglycerol (p<0.05). The animals treated with fish and olive oils presented better intestinal villosities preservation. Less deposition of lymphocytes was observed in the flaxseed group (p<0.001).
  
  
  CONCLUSIONS
  This study demonstrated that flaxseed, olive and fish oils present different responses than soy oil for the intestinal mucosa preservation and lymphocyte proliferation in Wistar rats.
authors.affiliation: Department of Nutrition and Health, UFV, Viçosa, MG, Brazil.
authors.forename: Damiana Diniz
authors.initials: DD
authors.lastname: Rosa
authors.forename: Regiane Lopes de
authors.initials: RL
authors.lastname: Sales
authors.forename: Luis Fernando de Sousa
authors.initials: LF
authors.lastname: Moraes
authors.forename: Fabíola Cesário
authors.initials: FC
authors.lastname: Lourenço
authors.forename: Clóvis Andrade
authors.initials: CA
authors.lastname: Neves
authors.forename: Céphora Maria
authors.initials: CM
authors.lastname: Sabarense
authors.forename: Sônia Machado Rocha
authors.initials: SM
authors.lastname: Ribeiro
authors.forename: Maria do Carmo Gouveia
authors.initials: Mdo C
authors.lastname: Peluzio
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002465:Cell Movement / Q000187:drug effects; D004041:Dietary Fats / Q000378:metabolism / Q000494:pharmacology; D005395:Fish Oils / Q000378:metabolism / Q000494:pharmacology; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D008043:Linseed Oil / Q000378:metabolism / Q000494:pharmacology; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis / Q000097:blood*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D023421:Models, Animal; D000069463:Olive Oil; D010938:Plant Oils / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013024:Soybean Oil / Q000378:metabolism / Q000494:pharmacology
chemical_list: D004041:Dietary Fats; D005395:Fish Oils; D008055:Lipids; D000069463:Olive Oil; D010938:Plant Oils; D013024:Soybean Oil; D008043:Linseed Oil