title: Cutis verticis gyrata and alopecia areata: a synchronous coincidence?
abstract: Cutis verticis gyrata (CVG) is a descriptive term for a scalp condition that is convoluted folds and deep furrows that resemble the surface of the cerebral cortex. It is categorized by the underlying etiology, as primary essential, primary non-essential and secondary. Alopecia areata (AA) is a common, organ specific autoimmune disease, and most AA cases are sporadic. There is clearly a strong genetic component. There is no established relationship between CVG and AA. We report one case which was affected with essential primary CVG and alopecia areata, and suggest a possibility of genetic association between CVG and AA, possibly both being related to mutations in the fibroblast growth factor receptor 2 (FGFR2).
authors.affiliation: Department of Dermatology, College of Medicine, Chung-Ang University, Dongjak-gu, Seoul, Korea.
authors.forename: Kwang Ho
authors.initials: KH
authors.lastname: Yoo
authors.forename: Jin Woong
authors.initials: JW
authors.lastname: Lee
authors.forename: Woo Sun
authors.initials: WS
authors.lastname: Jang
authors.forename: Kapsok
authors.initials: K
authors.lastname: Li
authors.forename: Seong Jun
authors.initials: SJ
authors.lastname: Seo
authors.forename: Chang Kwun
authors.initials: CK
authors.lastname: Hong
mesh_terms: D000328:Adult; D000506:Alopecia Areata / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D012536:Scalp Dermatoses / Q000209:etiology / Q000235:genetics* / Q000473:pathology