High prevalence of a novel porcine bocavirus in weanling piglets with respiratory tract symptoms in China.
This study presents the first evidence of infection by a novel porcine bocavirus (PBoV) in Chinese swine herds. The PCR detection results showed that PBoV was significantly more prevalent in weanling piglets (69.7%, 69/99) with respiratory tract symptoms than that in other samples (0-13.6%) (P < 0.01). Sequence analysis showed that the partial VP1/2 genes were highly conserved (99-100% identity), and only five frequent nucleotide mutation positions existed in Chinese PBoV strains. These data indicate that PBoV might be an emerging virus for swine respiratory tract diseases. This study could help us to better understand the epidemiology of PBoV.
Zhai
Shaolun
S
Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Aricultural Sciences, No. 518 Ziyue Road, Minhang District, Shanghai 200241, China.
Yue
Cheng
C
Wei
Zuzhang
Z
Long
Jinxue
J
Ran
Duoliang
D
Lin
Tao
T
Deng
Yu
Y
Huang
Lv
L
Sun
Lichang
L
Zheng
Haihong
H
Gao
Fei
F
Zheng
Hao
H
Chen
Shengnan
S
Yuan
Shishan
S
D000818:Animals; D001483:Base Sequence; D052660:Bocavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D002681:China; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012137:Respiratory System / Q000821:virology; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D014886:Weaning