title: Oocyte cryopreservation: a feasible fertility preservation option for reproductive age cancer survivors.
abstract: OBJECTIVE
  To compare oocyte cryopreservation cycles performed in cancer patients to those of infertile women.
  
  
  METHODS
  Cancer patients referred for fertility preservation underwent counseling in compliance with the ASRM; those electing oocyte cryopreservation were included. Ovarian stimulation was achieved with injectable gonadotropins and freezing was performed using slow-cooling and vitrification methods.
  
  
  RESULTS
  Fifty cancer patients (mean age 31 y) underwent oocyte cryopreservation; adequate ovarian stimulation was achieved in 10 ± 0.3 days. The outcome from these cycles included a mean peak estradiol of 2,376 pg/ml and an average of 19 oocytes retrieved (15 mature oocytes were cryopreserved/cycle). All patients tolerated ovarian hyperstimulation. There were no significant differences noted between cryopreservation cycles performed in cancer patients and in women without malignancy.
  
  
  CONCLUSIONS
  Oocyte cryopreservation appears to be a feasible fertility preservation method for reproductive-age women diagnosed with cancer. This modality is not only effective but also, providing a multidiscipline effort, can be completed in timely fashion.
authors.affiliation: NYU Fertility Center, NYU School of Medicine, New York, NY 10016, USA. nnoyes01@gmail.com
authors.forename: Nicole
authors.initials: N
authors.lastname: Noyes
authors.forename: Patty Ann
authors.initials: PA
authors.lastname: Labella
authors.forename: James
authors.initials: J
authors.lastname: Grifo
authors.forename: Jaime M
authors.initials: JM
authors.lastname: Knopman
mesh_terms: D000367:Age Factors; D015925:Cryopreservation; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control; D009369:Neoplasms; D009865:Oocytes; D010062:Ovulation Induction; D017741:Survivors