Flaxseed, olive and fish oil influence plasmatic lipids, lymphocyte migration and morphometry of the intestinal of Wistar rats.
OBJECTIVE
Evaluate the effect of flaxseed, olive and fish oil on the lipid profile, preservation of villosities and lymphocyte migration in the intestinal mucosa of Wistar rats.


METHODS
Thirty Wistar male rats were divided into four groups, which received the AIN-93M diet, with changes only to their lipid source: flaxseed, olive, fish, and soy oil (control group). The serum was separated for the biochemical parameter analysis. A histological evaluation was performed in the ileal portion.


RESULTS
The group which was fed fish oil presented lower values when compared to the other treatments for Total Cholesterol, High-density Lipoprotein Cholesterol and Triacylglycerol (p<0.05). The animals treated with fish and olive oils presented better intestinal villosities preservation. Less deposition of lymphocytes was observed in the flaxseed group (p<0.001).


CONCLUSIONS
This study demonstrated that flaxseed, olive and fish oils present different responses than soy oil for the intestinal mucosa preservation and lymphocyte proliferation in Wistar rats.
Rosa
Damiana Diniz
DD
Department of Nutrition and Health, UFV, Viçosa, MG, Brazil.
Sales
Regiane Lopes de
RL
Moraes
Luis Fernando de Sousa
LF
Lourenço
Fabíola Cesário
FC
Neves
Clóvis Andrade
CA
Sabarense
Céphora Maria
CM
Ribeiro
Sônia Machado Rocha
SM
Peluzio
Maria do Carmo Gouveia
Mdo C
D000704:Analysis of Variance; D000818:Animals; D002465:Cell Movement / Q000187:drug effects; D004041:Dietary Fats / Q000378:metabolism / Q000494:pharmacology; D005395:Fish Oils / Q000378:metabolism / Q000494:pharmacology; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D008043:Linseed Oil / Q000378:metabolism / Q000494:pharmacology; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis / Q000097:blood*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D023421:Models, Animal; D000069463:Olive Oil; D010938:Plant Oils / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013024:Soybean Oil / Q000378:metabolism / Q000494:pharmacology
D004041:Dietary Fats; D005395:Fish Oils; D008055:Lipids; D000069463:Olive Oil; D010938:Plant Oils; D013024:Soybean Oil; D008043:Linseed Oil