title: Identification of Y chromosome genetic variations in Chinese indigenous horse breeds.
abstract: Y chromosome acts as a single nonrecombining unit that is male specific and in effect haploid, thus ensuring the preservation of mutational events as a single haplotype via male lines. In this study, 6 Y chromosome-specific microsatellites (SSR) were tested for the patrilineal genetic variations of 573 male samples from Chinese domestic horse (30 breeds), Przewalski's horse, and donkey. All the 6 loci appeared as a haplotype block in Przewalski's horse and the domestic donkey. There were notable differences, however, at Y chromosome markers between horse and donkey. There were 2 haplotypes of Eca.YA16 in the domestic horse breeds, Haplotype A (Allele A: 156 bp) and Haplotype B (Allele B: 152 bp). Allele A was the common allele among 30 horse breeds, and Allele B was found in 11 horse breeds. This is the first description of a Y chromosome variant for horses. The 2 haplotypes of Y chromosome discovered in the domestic horse breeds in China could be helpful in unveiling their intricate genetic genealogy.
authors.affiliation: Animal Genetic Resources Laboratory, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
authors.forename: Yinghui
authors.initials: Y
authors.lastname: Ling
authors.forename: Yuehui
authors.initials: Y
authors.lastname: Ma
authors.forename: Weijun
authors.initials: W
authors.lastname: Guan
authors.forename: Yuejiao
authors.initials: Y
authors.lastname: Cheng
authors.forename: Yanping
authors.initials: Y
authors.lastname: Wang
authors.forename: Jianlin
authors.initials: J
authors.lastname: Han
authors.forename: Dapeng
authors.initials: D
authors.lastname: Jin
authors.forename: Lai
authors.initials: L
authors.lastname: Mang
authors.forename: Halik
authors.initials: H
authors.lastname: Mahmut
mesh_terms: D000483:Alleles; D000818:Animals; D002681:China; D018397:Equidae / Q000235:genetics; D014644:Genetic Variation; D006239:Haplotypes; D006736:Horses / Q000235:genetics*; D008297:Male; D018895:Microsatellite Repeats; D010802:Phylogeny; D014998:Y Chromosome / Q000235:genetics*