title: Prevalence, self-care behaviors, and self-care activities for peripheral neuropathy symptoms of HIV/AIDS.
abstract: As part of a larger randomized controlled trial examining the efficacy of an HIV/AIDS symptom management manual (n = 775), this study examined the prevalence of peripheral neuropathy in HIV-infected individuals at 12 sites in the USA, Puerto Rico, and Africa. Neuropathy was reported by 44% of the sample; however, only 29.4% reported initiating self-care behaviors to address the neuropathy symptoms. Antiretroviral therapy was found to increase the frequency of neuropathy symptoms, with an increased mean intensity of 28%. A principal axis factor analysis with Promax rotation was used to assess the relationships in the frequency of use of the 18 self-care activities for neuropathy, revealing three distinct factors: (i) an interactive self-care factor; (ii) a complementary medicine factor; and (iii) a third factor consisting of the negative health items of smoking, alcohol, and street drugs. The study's results suggest that peripheral neuropathy is a common symptom and the presence of neuropathy is associated with self-care behaviors to ameliorate HIV symptoms. The implications for nursing practice include the assessment and evaluation of nursing interventions related to management strategies for neuropathy.
authors.affiliation: Division of Global Health Equity, Brigham and Women's Hospital and MGH Institute of Health Professions, Boston, MA 02120, USA. pnicholas@partners.org
authors.forename: Patrice K
authors.initials: PK
authors.lastname: Nicholas
authors.forename: Joachim
authors.initials: J
authors.lastname: Voss
authors.forename: Dean
authors.initials: D
authors.lastname: Wantland
authors.forename: Teri
authors.initials: T
authors.lastname: Lindgren
authors.forename: Emily
authors.initials: E
authors.lastname: Huang
authors.forename: William L
authors.initials: WL
authors.lastname: Holzemer
authors.forename: Yvette
authors.initials: Y
authors.lastname: Cuca
authors.forename: Shahnaz
authors.initials: S
authors.lastname: Moezzi
authors.forename: Carmen
authors.initials: C
authors.lastname: Portillo
authors.forename: Suzanne
authors.initials: S
authors.lastname: Willard
authors.forename: John
authors.initials: J
authors.lastname: Arudo
authors.forename: Kenn
authors.initials: K
authors.lastname: Kirksey
authors.forename: Inge B
authors.initials: IB
authors.lastname: Corless
authors.forename: María E
authors.initials: ME
authors.lastname: Rosa
authors.forename: Linda
authors.initials: L
authors.lastname: Robinson
authors.forename: Mary J
authors.initials: MJ
authors.lastname: Hamilton
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Sefcik
authors.forename: Sarie
authors.initials: S
authors.lastname: Human
authors.forename: Marta
authors.initials: M
authors.lastname: Rivero-Mendez
authors.forename: Mary
authors.initials: M
authors.lastname: Maryland
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Nokes
authors.forename: Lucille
authors.initials: L
authors.lastname: Eller
authors.forename: Jeanne
authors.initials: J
authors.lastname: Kemppainen
authors.forename: Carol
authors.initials: C
authors.lastname: Dawson-Rose
authors.forename: John M
authors.initials: JM
authors.lastname: Brion
authors.forename: Elli H
authors.initials: EH
authors.lastname: Bunch
authors.forename: Maureen
authors.initials: M
authors.lastname: Shannon
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Nicholas
authors.forename: Ana
authors.initials: A
authors.lastname: Viamonte-Ros
authors.forename: Catherine A
authors.initials: CA
authors.lastname: Bain
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods; D015331:Cohort Studies; D000529:Complementary Therapies; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010349:Patient Compliance / Q000706:statistics & numerical data*; D010523:Peripheral Nervous System Diseases / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy*; D015995:Prevalence; D018570:Risk Assessment; D012309:Risk-Taking; D012648:Self Care / Q000592:standards* / Q000639:trends; D012720:Severity of Illness Index; D017678:Sex Distribution; D014481:United States; D055815:Young Adult
chemical_list: D000700:Analgesics