title: Isolation and analysis of bioactive constituents of sour cherry (Prunus cerasus) seed kernel: an emerging functional food.
abstract: A plant-based diet reduces the risk for the development of several chronic diseases, such as ischemic heart disease or cancer due to natural compounds found in plants. Numerous cereals, berries, fruits, and vegetables, including sour cherry (Prunus cerasus), which is a favored fruit worldwide, contain biological active components. The antioxidant components of the sour cherry seed kernel have not been investigated until now. The aim of our study was to isolate and analyze the bioactive constituents of sour cherry seed kernel. We separated the oil fraction of the kernel; then the remaining solid fraction was dried, and the oil-free kernel extract was further analyzed. Our results show that sour cherry seed kernel oil contains vegetable oils including unsaturated fatty acids, oleic acids, alpha-tocopherol, tocotrienols, and tocopherol-like components. The components of the solid fraction include various bioactive structures such as polyphenols, flavonoids, vegetable acids, and pro- and anthocyanidins, which could have useful therapeutic effects in the prevention of various vascular diseases.
authors.affiliation: Department of Pharmacology, Faculty of Pharmacy, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.
authors.forename: Istvan
authors.initials: I
authors.lastname: Bak
authors.forename: Istvan
authors.initials: I
authors.lastname: Lekli
authors.forename: Bela
authors.initials: B
authors.lastname: Juhasz
authors.forename: Edit
authors.initials: E
authors.lastname: Varga
authors.forename: Balazs
authors.initials: B
authors.lastname: Varga
authors.forename: Rudolf
authors.initials: R
authors.lastname: Gesztelyi
authors.forename: Levente
authors.initials: L
authors.lastname: Szendrei
authors.forename: Arpad
authors.initials: A
authors.lastname: Tosaki
mesh_terms: D000975:Antioxidants / Q000032:analysis* / Q000302:isolation & purification*; D005419:Flavonoids / Q000032:analysis / Q000302:isolation & purification; D055951:Functional Food / Q000032:analysis*; D006801:Humans; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification*; D010938:Plant Oils / Q000032:analysis / Q000302:isolation & purification; D059808:Polyphenols; D027861:Prunus / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D010938:Plant Oils; D059808:Polyphenols