Corticosteroids as adjunctive therapy in severe blastomycosis-induced acute respiratory distress syndrome in an immunosuppressed patient.
We describe the case of an immunosuppressed transplant recipient with disseminated blastomycosis (cutaneous, central nervous system, and pulmonary infection) complicated by septic shock and severe, refractory acute respiratory distress syndrome that improved markedly and rapidly after the addition of corticosteroids to the antifungal regimen.
Plamondon
Mireille
M
Department of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, Canada. mireille.plamondon.chum@ssss.gouv.qc.ca
Lamontagne
François
F
Allard
Catherine
C
Pépin
Jacques
J
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D001759:Blastomycosis / Q000150:complications* / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000382:microbiology*; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000935:Antifungal Agents