Indication for skin-sparing mastectomy with or without nipple preservation for primary breast cancer.
Skin-sparing mastectomy (SSM) is one of the available operation methods for breast cancer. We discuss here indications for SSM for primary breast cancer. We carried out SSM for 28 patients with breast cancer. Their clinical features were compared with those in patients who underwent breast-conserving treatment (BCT). Fifteen of the 28 patients received SSM according to schedule. The remaining 13 patients who were scheduled to undergo BCT received SSM because of involvement of the surgical margin. Clinical features indicating suitability for SSM included extensive intraductal cancer growth and multicentricity. The length of intraductal cancer growth in these patients was significantly greater than that in 24 patients who received BCT (2.28 versus 0.571 cm; P = 0.000078). Tumor size and tumor-nipple distance were not indicating factors for this treatment. SSM, which is advantageous in terms of aesthetic outcome and oncologic safety, may be widely indicated after careful evaluation by magnetic resonance imaging or pathologic examination.
Kontani
Keiichi
K
Department of Respiratory, Breast, and Endocrine Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun 761-0793, Japan. konbat@med.kagawa-u.ac.jp
Murazawa
Chisa
C
Norimura
Shoko
S
Yamashita
Kanako
K
Fujiwara-Honjo
Naomi
N
Ohtani
Masahiro
M
Date
Manabu
M
Kushida
Yoshio
Y
Muneuchi
Gan
G
Haba
Reiji
R
Yokomise
Hiroyasu
H
Yamauchi
Akira
A
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008408:Mastectomy / Q000379:methods*; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009558:Nipples; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism
D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human