Influenza and bacterial pneumonia--constant companions.
Sequential or concomitant influenza and bacterial pneumonia are two common syndromes seen in community-acquired pneumonia. Inadequacies of diagnostic testing make separating simple pneumonia with either bacteria or influenza from concomitant or sequential influenza with both microorganisms difficult, although the novel 2009 H1N1 epidemic may improve the availability of molecular testing for viruses. Given the frequency of viral pneumonia and diagnostic limitations, empirical antivirals may be underutilized in community-acquired pneumonia. Thankfully, increasingly effective vaccines appear to disrupt this synergistic relationship.
Wunderink
Richard G
RG
Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, 676 North St, Clair Street, Suite 14-044, Chicago, IL 60611, USA. r-wunderink@northwestern.edu
D003428:Cross Infection; D003937:Diagnosis, Differential; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis*; D018410:Pneumonia, Bacterial / Q000150:complications / Q000175:diagnosis*