Angiogenesis, lymphangiogenesis, growth pattern, and tumor emboli in inflammatory breast cancer: a review of the current knowledge.
This objective of the current review was to provide the reader with a comprehensive summary of the literature related to 3 important and inter-related features of the biology of inflammatory breast cancer (IBC): angiogenesis, lymphangiogenesis, and the formation of tumor emboli. Information derived from animal models of IBC as well as from translational studies using tissue samples of patients with IBC are discussed.
Vermeulen
Peter B
PB
Translational Cancer Research Group and Pathology Department, Cancer Center of the Saint-Augustinus Hospital, University of Antwerp, Wilrijk, Belgium. peter.vermeulen2@telenet.be
van Golen
Kenneth L
KL
Dirix
Luc Y
LY
D043925:Angiogenesis Inducing Agents / Q000032:analysis; D001943:Breast Neoplasms / Q000098:blood supply / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D042583:Lymphangiogenesis; D008325:Mammary Neoplasms, Experimental / Q000473:pathology; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D009389:Neovascularization, Pathologic; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors
D043925:Angiogenesis Inducing Agents; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A