title: [Interpretation of false positive results of biochemical prenatal tests].
abstract: Modern, non-invasive prenatal diagnostics based on biochemical and ultrasonographic markers of fetal defects allows us to calculate the risk of fetal chromosomal aneuploidies with high sensitivity and specificity An introduction of biochemical, non-invasive prenatal tests turned out to result in frequent false positive results of these tests in cases when invasive diagnostics does not confirm fetal defects. However prospective analysis of these cases showed numerous complications in the third trimester of the pregnancies.
authors.affiliation: Klinika Medycyny Płodu i Ginekologii I Katedry Ginekologii i Połoznictwa Uniwersytetu Medycznego w Łodzi. piotr.sieroszewski@umed.lodz.pl
authors.forename: Piotr
authors.initials: P
authors.lastname: Sieroszewski
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Słowakiewicz
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Perenc
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D005189:False Positive Reactions; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D012680:Sensitivity and Specificity