[Immunohistochemical presentation of fibromodulin during wound healing of periodontal cells].
OBJECTIVE
To investigate immunohistochemical presentation of fibromodulin in vitro during wound healing of three types of periodontal cells and discuss the role of fibromodulin.


METHODS
Cultured periodontal cells were wounded and followed by observation up to 7 days. The immunohistochemical expression of fibromodulin in periodontal cells was observed.


RESULTS
Immunohistochemical localization of fibromodulin during cellular wound healing showed that newly migrating periodontal cells toward the wound area were expressed strongly for fibromodulin at day 1 after wounding; thereafter, fibromodulin expression was noted stronger in newly migrating periodontal cells localized in the central part of the wound area than those around the wound area.


CONCLUSIONS
These data suggest that fibromodulin may be involved in the early events of wound healing for periodontal cells.
Qian
Hong
H
Dept. of Pediatric Dentistry, Guangdong Provincial Stomatological Hospital, Stomatological Hospital Affiliated to Southern Medical University, Guangzhou 510280, China.
Huang
Qun
Q
Xiao
Yin
Y
D002478:Cells, Cultured; D016326:Extracellular Matrix Proteins; D000071235:Fibromodulin; D006801:Humans; D010513:Periodontal Ligament; D011509:Proteoglycans; D014945:Wound Healing
D016326:Extracellular Matrix Proteins; C000604330:FMOD protein, human; D011509:Proteoglycans; D000071235:Fibromodulin