title: Duration of aortic cross-clamping during elective open abdominal aortic aneurysm repair operations and postoperative cardiac/renal function.
abstract: OBJECTIVE
  To determine the effect of the duration of aortic cross-clamping during elective infrarenal abdominal aortic aneurysm (AAA) repair operations on postoperative cardiac and renal function.
  
  
  METHODS
  Fifty patients scheduled for open infrarenal AAA repair underwent pre- and postoperative evaluation of serum creatinine and troponin levels. The patients were divided into 2 groups according to the duration of aortic cross-clamping (Group A: <50 min; Group B: >50 min).
  
  
  RESULTS
  A prolonged (>50 min) duration of aortic cross-clamping was associated with an increase in post-operative serum troponin (P<0.001) and serum creatinine values (P<0.001). A prolonged duration of aortic cross-clamping was the only independent predictor of postoperative renal (r=0.534; P<0.001) and cardiac dysfunction (r=0.578; P<0.001).
  
  
  CONCLUSIONS
  Elective open infrarenal AAA repair procedures may be associated with mild/moderate cardiac and/or renal dysfunction, especially when aortic cross-clamping time is prolonged. Measuring serum troponin and creatinine levels before and after such operations may reveal an often clinically-silent post-operative cardiac and/or renal dysfunction.
authors.affiliation: Department of Anesthesiology, Red Cross Hospital, Athens, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Georgakis
authors.forename: K I
authors.initials: KI
authors.lastname: Paraskevas
authors.forename: N
authors.initials: N
authors.lastname: Bessias
authors.forename: D P
authors.initials: DP
authors.lastname: Mikhailidis
authors.forename: V
authors.initials: V
authors.lastname: Andrikopoulos
authors.forename: I
authors.initials: I
authors.lastname: Katsouli-Liapis
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D015415:Biomarkers / Q000097:blood; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D003250:Constriction; D003404:Creatinine / Q000097:blood; D017558:Elective Surgical Procedures; D005260:Female; D006115:Greece; D006331:Heart Diseases / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood
chemical_list: D015415:Biomarkers; D019210:Troponin I; D003404:Creatinine