title: The management of Peyronie's disease: evidence-based 2010 guidelines.
abstract: BACKGROUND
  The field of Peyronie's disease is evolving and there is need for a state-of-the-art information in this area.
  
  
  OBJECTIVE
  To develop an evidence-based state-of-the-art consensus report on the management of Peyronie's disease.
  
  
  METHODS
  To provide state-of-the-art knowledge regarding the prevalence, etiology, medical and surgical management of Peyronie's Disease, representing the opinion of leading experts developed in a consensus process over a 2-year period.
  
  
  METHODS
  Expert opinion was based on grading of evidence-based medical literature, widespread internal committee discussion, public presentation, and debate.
  
  
  CONCLUSIONS
  The real etiology of Peyronie's disease and the mechanisms of formation of the plaque still remain obscure. Although conservative management is obtaining a progressively larger consensus among the experts, surgical correction still remains the mainstay treatment for this condition.
authors.affiliation: Institute of Urology, London, UK. dralph@andrology.co.uk
authors.forename: David
authors.initials: D
authors.lastname: Ralph
authors.forename: Nestor
authors.initials: N
authors.lastname: Gonzalez-Cadavid
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mirone
authors.forename: Sava
authors.initials: S
authors.lastname: Perovic
authors.forename: Michael
authors.initials: M
authors.lastname: Sohn
authors.forename: Mustafa
authors.initials: M
authors.lastname: Usta
authors.forename: Laurence
authors.initials: L
authors.lastname: Levine
mesh_terms: D000818:Animals; D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D010411:Penile Induration / Q000601:surgery / Q000628:therapy*; D015917:Penile Prosthesis; D015995:Prevalence; D014481:United States / Q000453:epidemiology; D013521:Urologic Surgical Procedures, Male / Q000379:methods