title: Cellular homeostasis: coping with ER overload during an immune response.
abstract: Host cells secrete antimicrobial proteins en masse to counter extracellular pathogens, placing a strain on the endoplasmic reticulum. The interplay between defence and cellular homeostasis has now been dissected genetically in Caenorhabditis elegans.
authors.affiliation: Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, Case 906, 13288 Marseille cedex 9, France. ewbank@ciml.univ-mrs.fr
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Ewbank
authors.forename: Nathalie
authors.initials: N
authors.lastname: Pujol
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006706:Homeostasis; D007113:Immunity, Innate