title: Coordination polymer particles as potential drug delivery systems.
abstract: Micro- and nanoscale coordination polymer particles can be used for encapsulating and delivering drugs. In vitro cancer cell cytotoxicity assays showed that these capsules readily release doxorubicin, which shows anticancer efficacy. The results from this work open up new avenues for metal-organic capsules to be used as potential drug delivery systems.
authors.affiliation: Centro de Investigación en Nanociencia y Nanotecnología (ICN-CSIC) Campus UAB, 08193 Bellaterra, Spain.
authors.forename: Inhar
authors.initials: I
authors.lastname: Imaz
authors.forename: Marta
authors.initials: M
authors.lastname: Rubio-Martínez
authors.forename: Lorena
authors.initials: L
authors.lastname: García-Fernández
authors.forename: Francisca
authors.initials: F
authors.lastname: García
authors.forename: Daniel
authors.initials: D
authors.lastname: Ruiz-Molina
authors.forename: Jordi
authors.initials: J
authors.lastname: Hernando
authors.forename: Victor
authors.initials: V
authors.lastname: Puntes
authors.forename: Daniel
authors.initials: D
authors.lastname: Maspoch
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004337:Drug Carriers / Q000737:chemistry*; D016503:Drug Delivery Systems; D018922:HL-60 Cells; D006801:Humans; D008670:Metals / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry; D009930:Organic Chemicals / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D000903:Antibiotics, Antineoplastic; D004337:Drug Carriers; D008670:Metals; D009930:Organic Chemicals; D011108:Polymers; D004317:Doxorubicin