[Fatal course of a patient during in vitro fertilisation treatment].
Chylomicronaemia syndrome is a rare disorder primarily caused by a genetic defect which increases triglycerides, combined with a secondary inducing factor. We describe the fatal course of a 33-year-old, pregnant woman with known dyslipidaemia who had been treated with in vitro fertilisation and developed chylomicronaemia syndrome with severe hypertriglyceridaemia, hypertriglyceridaemia-induced acute pancreatitis and septic shock. Appropriate treatment including close monitoring, severe restriction of dietary fat intake and early plasmapheresis is emphasized - especially during pregnancy.
Sørensen
Martin Kryspin
MK
Anaestesi- og Operationsklinikken, HovedOrtoCentret, Rigshospitalet, 2100 København Ø, Denmark. martin@kryspin.dk
Møller-Sørensen
Hasse
H
Svane
Christian
C
Jensen
Carsten Huus
CH
Lange
Kai Henrik Wiborg
KH
Tybjaerg-Hansen
Anne
A
D000328:Adult; D002914:Chylomicrons / Q000097:blood*; D017809:Fatal Outcome; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood / Q000209:etiology; D010195:Pancreatitis / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000209:etiology; D012772:Shock, Septic / Q000209:etiology; D013577:Syndrome
D002914:Chylomicrons