[Ocular manifestations in HIV/AIDS patients undergoing highly active antiretroviral treatment (HAART) in Togo].
OBJECTIVE
The twofold purpose of this study in people living with human immunodeficiency virus (PLHIV/AIDS) and undergoing highly active antiretroviral treatment (HAART) was to determine the prevalence of ocular manifestations and its correlation with CD4 T-cell count.


METHODS
All patients who attended 2 NGO care centers that manage PLHIV/AIDS in Lomé, Togo between August and October 2005 were recruited. CD4 T-cell counts and use of antiretroviral treatment was noted. A thorough eye examination was performed in all cases.


RESULTS
A total of 422 PLHIV/SIDA were recruited including 281 who were undergoing HAART. The sex-ratio was 2 female/1 male. Mean age was 34 +/- 2294 years. Involvement of the anterior segment was observed in 36.3% of patients and involvement of the posterior segment in 54.1%. The second most common ocular manifestation was ophthalmic herpes zoster of the anterior segment (19.6%) secondary to conjunctivitis (57.8%). One case of palpebral and conjunctival Kaposi's sarcoma was noted. The most common type of posterior segment involvement was cotton-wool nodules (35.5%). Five cases of CMV retinitis were observed.


CONCLUSIONS
A longitudinal study in PLHIV/AIDS will be needed to better evaluate the correlation between ocular manifestations and CD4 T-cell count.
Ayena
K D
KD
Service d'ophtalmologie CHU Tokoin, Lomé, Togo.
Amedome
K M
KM
Agbo
A R D
AR
Kpetessou-Ayivon
A L
AL
Dzidzinyo
B K
BK
Djagnikpo
P A
PA
Banla
M
M
Balo
K P
KP
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D003231:Conjunctivitis / Q000139:chemically induced*; D015817:Eye Infections / Q000139:chemically induced*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006562:Herpes Zoster / Q000209:etiology*; D006801:Humans; D008297:Male; D014037:Togo