The role of endorectal magnetic resonance imaging in predicting extraprostatic extension and seminal vesicle invasion in clinically localized prostate cancer.
OBJECTIVE
We aimed to assess the clinical value of endorectal magnetic resonance imaging (MRI) in predicting extraprostatic extension and seminal vesicle invasion in patients with clinically localized prostate cancer.


METHODS
A total of 54 patients who underwent radical prostatectomy for clinically localized prostate cancer were retrospectively analyzed. The findings of endorectal MRI, performed at least 3 weeks after biopsy, were compared with the pathological results of radical prostatectomy specimens. The sensitivity, specificity, and accuracy of the detection of extraprostatic extension and seminal vesicle invasion were calculated.


RESULTS
The sensitivity, specificity, and accuracy of the endorectal MRI findings were 50.0%, 82.6%, and 77.8% for the detection of extraprostatic extension, respectively, and 75.0%, 92.0%, and 90.7% for the detection of seminal vesicle invasion, respectively. The sensitivity of endorectal MRI in the detection of extraprostatic extension improved as the Gleason score increased.


CONCLUSIONS
Endorectal MRI findings demonstrated modest sensitivity for predicting extraprostatic extension, whereas specificity was relatively high. In addition, endorectal MRI showed better sensitivity for detecting high-grade tumors.
Park
Seo Yong
SY
Department of Urology, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim
Jung Jun
JJ
Kim
Tae Heon
TH
Lim
Soo Hyun
SH
Han
Deok Hyun
DH
Park
Byung Kwan
BK
Kim
Chan Kyo
CK
Kwon
Ghee Young
GY
Choi
Han Yong
HY
Lee
Hyun Moo
HM