title: Microstructure, biocorrosion and cytotoxicity evaluations of rapid solidified Mg-3Ca alloy ribbons as a biodegradable material.
abstract: Rapidly solidified (RS) Mg–3Ca alloy ribbons were prepared by the melt-spinning technique at different wheel rotating speeds (15 m s(-1), 30 m s(-1) and 45 m s(-1) with the as-cast Mg–3Ca alloy ingot as a raw material. The RS45 Mg–3Ca alloy ribbon showed a much more fine grain size feature (approximately 200–500 nm) in comparison to the coarse grain size (50–100 μm)of the original as-cast Mg–3Ca alloy ingot. The corrosion electrochemical tests in simulated body fluid indicated that the corrosion rate of the as-cast Mg–3Ca alloy was strongly reduced by the RS procedure and tended to be further decreased with increasing wheel rotating speeds(1.43 mm yr(-1) for RS15, 0.94 mm yr(-1) for RS30 and 0.36 mm yr(-1) for RS45). The RS Mg–3Ca alloy ribbons showed more uniform corrosion morphology compared with the as-cast Mg–3Ca alloy after polarization. The cytotoxicity evaluation revealed that the three experimental as-spun Mg–3Ca alloy ribbon extracts did not induce toxicity to the L-929 cells,whereas the as-cast Mg–3Ca alloy ingot extract did. The L-929 cells showed more improved adhesion on the surfaces of the three as-spun Mg–3Ca alloy ribbons than that of the as-cast Mg–3Ca alloy ingot.
authors.affiliation: State Key Laboratory for Turbulence and Complex System and Department of Advanced Materials and Nanotechnology, College of Engineering, Peking University, Beijing 100871, People’s Republic of China.
authors.forename: X N
authors.initials: XN
authors.lastname: Gu
authors.forename: X L
authors.initials: XL
authors.lastname: Li
authors.forename: W R
authors.initials: WR
authors.lastname: Zhou
authors.forename: Y
authors.initials: Y
authors.lastname: Cheng
authors.forename: Y F
authors.initials: YF
authors.lastname: Zheng
mesh_terms: D020341:Absorbable Implants; D000497:Alloys / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000633:toxicity; D002118:Calcium / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects*; D003343:Corrosion; D006244:Hardness; D008274:Magnesium / Q000737:chemistry*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity* / Q000648:ultrastructure; D010316:Particle Size; D013499:Surface Properties
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D008274:Magnesium; D002118:Calcium