Mirazid in treatment of three zoonotic trematodes in Beni-Sweif and Dakhalia Governorates.
A total of 60 patients with schistosomiasis (40), fascialiosis (15) and heterophyiasis (5) were selected Beni-Sweif and Mansoura Districts and subjected to history taking, clinical examination, Kato thick smear, sedimentation and hatching test (for schistosomiasis cases) at the beginning of the study, 2 & 3 months after treatment with Oleo-resin of Myrrh (Mirazid) in a dose of 10 mg/kg/day for 6 consecutive days an hour before breakfast. The results showed a significant improvement in symptoms with minimal negligible or no side effects. The cure rates, 2 & 3 months after treatment were 80.7%% & 11.8%% for schistosomiasis, 93.3% & 6.6% for fascioliasis, and 100% for heterophyiasis. The clinical picture of schistosomiasis before treatments were easy fatigability, anorexia, nausea, vomiting, epigastria pain, abdominal distention, right upper guardant pain, colicky abdominal pain, left upper and/or lower guardant pain, abdominal rumbling, dysentery, diarrhea, rectal bleeding, constipation, and alternating bowel habit. Those of fascioliasis were abdominal distention, dripping of saliva, right upper guardant, colicky abdominal pain, weight loss, easy fatigability, intermittent jaundice, anorexia, nausea, vomiting, epigastria, left upper and/or lower quadrant pain, right layer quadrant pain, loin pain, abdominal rumbling, diarrhea, constipation, and alternating bowel habit. The safety and efficacy of C. molmol extract in treating heterophyiasis (100%), fascioliasis (100%) and schistosomiasis (92.5%) were documented.
Massoud
Ahmad M A
AM
Department of Tropical Medicine, Faculty of Medicine, Al-Azhar University, Nasr City, Cairo, Egypt.
El-Sherbini
Eman T
ET
Mos
Nagla
N
Saleh
Nagla Mostafa Kamel
NM
Abouel-Nour
Mohamed Fathy
MF
Morsy
Ayman T A
AT
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D002648:Child; D029744:Commiphora; D004534:Egypt / Q000453:epidemiology; D005209:Fasciola / Q000187:drug effects / Q000302:isolation & purification; D005260:Female; D006578:Heterophyidae / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D012116:Resins, Plant; D012547:Schistosoma / Q000187:drug effects / Q000302:isolation & purification; D014201:Trematode Infections / Q000188:drug therapy*; D055815:Young Adult
D000871:Anthelmintics; D010936:Plant Extracts; D012116:Resins, Plant; C587573:myrrh resin