title: White blood cell count and cardiovascular biomarkers of atherosclerosis.
abstract: OBJECTIVE
  To investigate the association with white blood cells (WBC) and atherosclerotic parameters including cardio-ankle vascular index (CAVI) and carotid intima-media thickness (CIMT) in the general population.
  
  
  METHODS
  We investigated the relationship between WBC count and metabolic syndrome components, CAVI and CIMT in 3738 Japanese study participants.
  
  
  RESULTS
  WBC count weakly correlated with CAVI in men (beta = 0.61, p = 0.043), but not in women (beta = 0.35, p = 0.17). On the other hand, WBC did not correlate with CIMT in either men or women (p = 0.41 and p = 0.71, respectively).
  
  
  CONCLUSIONS
  WBC count was associated with lipids, blood pressure and body mass index, although the correlations with CAVI and CIMT were weak or absent.
authors.affiliation: Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Yui
authors.initials: Y
authors.lastname: Sekitani
authors.forename: Naomi
authors.initials: N
authors.lastname: Hayashida
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kadota
authors.forename: Hironori
authors.initials: H
authors.lastname: Yamasaki
authors.forename: Norio
authors.initials: N
authors.lastname: Abiru
authors.forename: Mio
authors.initials: M
authors.lastname: Nakazato
authors.forename: Takahiro
authors.initials: T
authors.lastname: Maeda
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ozono
authors.forename: Noboru
authors.initials: N
authors.lastname: Takamura
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000097:blood* / Q000175:diagnosis; D015415:Biomarkers / Q000097:blood*; D001794:Blood Pressure; D015992:Body Mass Index; D002339:Carotid Arteries / Q000473:pathology*; D008076:Cholesterol, HDL / Q000097:blood; D003404:Creatinine / Q000097:blood; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007958:Leukocyte Count; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012737:Sex Factors; D012907:Smoking; D014280:Triglycerides / Q000097:blood; D017540:Tunica Media / Q000473:pathology*
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D003404:Creatinine; D006442:Glycated Hemoglobin; D014280:Triglycerides