title: [Allergenic environment in asthmatic children in Annaba (Algeria)].
abstract: We determined blood levels of total and specific immunoglobulins E in a cohort of 75 asthmatic children at Annaba (mean age: 9 years, sex ratio M/F: 1,64). Analysis clinical investigation and biological results allowed us to estimate the clinico-biological relations in this population. We showed that: atopy based on family criteria was very frequent (74%); the symptoms of atopy associated with asthma were frequent for atopic children (96%) whose majority (46%) had severe asthma (grade 3) that required treatment. Sensitization to trophallergens was rare in this population and always associated with sensitizations to pneumallergens (acariens: 2/3; cockroaches: 50%). Sensitizations to pneumallergens seemed promoted by climatic conditions in the area of Annaba that increased the risk of developing allergic diseases.
authors.affiliation: Laboratoire de biochimie et microbiologie appliquées, Unité d'immunologie, Faculté des sciences, Université Badji Mokhtar, Annaba, Algérie. amelibis@yahoo.fr
authors.forename: Amel
authors.initials: A
authors.lastname: Boumendjel
authors.forename: Arlette
authors.initials: A
authors.lastname: Tridon
authors.forename: Sylvie
authors.initials: S
authors.lastname: Ughetto
authors.forename: Mahfoud
authors.initials: M
authors.lastname: Messarah
authors.forename: Mohamed Salah
authors.initials: MS
authors.lastname: Boulakoud
mesh_terms: D000293:Adolescent; D000462:Algeria / Q000453:epidemiology; D000485:Allergens / Q000276:immunology*; D001249:Asthma / Q000453:epidemiology* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D012720:Severity of Illness Index
chemical_list: D000485:Allergens; D007073:Immunoglobulin E