Epidermotropic metastatic mucoepidermoid carcinoma.
Mucoepidermoid carcinoma (MEC), an invasive malignant neoplasm composed of mucus-secreting, epidermoid, and intermediate cells in varying proportions, is the commonest malignant salivary gland neoplasm in adults. Cutaneous metastases from the same, although not entirely common, has been previously reported but are typically confined to dermis. In this report, we present a case of MEC presenting as a cutaneous metastasis. A histologic feature unique to this case was epidermotropism, previously not noted in either metastatic or primary MEC.
Abbas
Ossama
O
Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA.
Reddy
Kavitha
K
Demierre
Marie-France
MF
Blanchard
Rita A
RA
Mahalingam
Meera
M
D000310:Adrenal Gland Neoplasms / Q000556:secondary; D001706:Biopsy; D018277:Carcinoma, Mucoepidermoid / Q000556:secondary*; D002528:Cerebellar Neoplasms / Q000556:secondary; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000556:secondary*