title: Durable responses to Erlotinib despite KRAS mutations in two patients with metastatic lung adenocarcinoma.
authors.affiliation: SITEP (Phase I Unit), Department of Medical Oncology, Institut Gustave Roussy, Villejuif; General Oncology Department, Centre Oscar Lambret, Lille.
authors.forename: C
authors.initials: C
authors.lastname: Ferté
authors.affiliation: Department of Medical Oncology, Institut Gustave Roussy, Villejuif.
authors.forename: B
authors.initials: B
authors.lastname: Besse
authors.affiliation: General Oncology Department, Centre Oscar Lambret, Lille.
authors.forename: E
authors.initials: E
authors.lastname: Dansin
authors.affiliation: Department of Pneumology, Antoine Beclere Hospital, Assistance Publique-Hopitaux de Paris, Clamart.
authors.forename: F
authors.initials: F
authors.lastname: Parent
authors.affiliation: Molecular Biology Laboratory (Oncology Unit), Centre Hospitalier Universitaire Régional, Lille.
authors.forename: M-P
authors.initials: MP
authors.lastname: Buisine
authors.affiliation: Department of Pathology, CHRU, Lille, France.
authors.forename: M-C
authors.initials: MC
authors.lastname: Copin
authors.affiliation: General Oncology Department, Centre Oscar Lambret, Lille.
authors.forename: N
authors.initials: N
authors.lastname: Penel
authors.affiliation: SITEP (Phase I Unit), Department of Medical Oncology, Institut Gustave Roussy, Villejuif. Electronic address: soria@igr.fr.
authors.forename: J-C
authors.initials: JC
authors.lastname: Soria
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000069347:Erlotinib Hydrochloride; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D009154:Mutation / Q000502:physiology; D009362:Neoplasm Metastasis; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D011799:Quinazolines / Q000627:therapeutic use*; D012074:Remission Induction; D013997:Time Factors; D018631:ras Proteins / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D011799:Quinazolines; D000069347:Erlotinib Hydrochloride; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins