Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones.
A convenient synthesis of benzyl-gamma-butyrolactone derivatives via intramolecular Michael addition reaction of nitro-substituted aryl allyl beta-ketocarboxylates is reported. The method features simple operation, mild reaction conditions and high efficiency.
He
Hu
H
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, P. R. China.
Dai
Li-Xin
LX
You
Shu-Li
SL
D002384:Catalysis; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D014508:Urea / Q000031:analogs & derivatives / Q000737:chemistry
D007783:Lactones; D014508:Urea; C483182:N,N'-dibutylurea