title: Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis.
abstract: We report the rapid and dramatic efficacy of propranolol in 8 infants with infantile hepatic hemangiomas. The degree of response varied from a significant improvement to a complete resolution of hepatic lesions. Heart failure and hypothyroidism resolved, and hepatomegaly decreased. No side-effects of the drug were noted.
authors.affiliation: Dermatology Department, Paul Sabatier University and the Department of Dermatology, Children's Hospital, Toulouse, France. mazereeuw-hautier.j@chu-toulouse.fr
authors.forename: Juliette
authors.initials: J
authors.lastname: Mazereeuw-Hautier
authors.forename: Peter H
authors.initials: PH
authors.lastname: Hoeger
authors.forename: Sarah
authors.initials: S
authors.lastname: Benlahrech
authors.forename: Amir
authors.initials: A
authors.lastname: Ammour
authors.forename: Pierre
authors.initials: P
authors.lastname: Broue
authors.forename: Julie
authors.initials: J
authors.lastname: Vial
authors.forename: Gerard
authors.initials: G
authors.lastname: Ohanessian
authors.forename: Christine
authors.initials: C
authors.lastname: Léauté-Labrèze
authors.forename: Marc
authors.initials: M
authors.lastname: Labenne
authors.forename: Pierre
authors.initials: P
authors.lastname: Vabres
authors.forename: Jochen
authors.initials: J
authors.lastname: Rössler
authors.forename: Christine
authors.initials: C
authors.lastname: Bodemer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D006333:Heart Failure / Q000517:prevention & control; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D014665:Vasodilator Agents; D011433:Propranolol