Calpain-mediated proteolysis of fast transported proteins in nerve terminals of rabbit retinal ganglion cells.
In vitro administration of calpain to microsomal fractions from regions containing nerve terminals of retinal ganglion cells causes a selective degradation of certain rapidly axonally transported membrane proteins. The major part of the degradation products were in the size of 30-60 kDa as shown by gel filtration.
Hall
C M
CM
Institute of Neurobiology, University of Göteborg, Göteborg, Sweden.
Nilsson
E
E
Karlsson
J O
JO