title: Peroxisome biogenesis and positioning.
abstract: Plant peroxisomes are extremely dynamic, moving and undergoing changes of shape in response to metabolic and environmental signals. Matrix proteins are imported via one of two import pathways, depending on the targeting signal within the protein. Each pathway has a specific receptor but utilizes common membrane-bound translocation machinery. Current models invoke receptor recycling, which may involve cycles of ubiquitination. Some components of the import machinery may also play a role in proteolytic turnover of matrix proteins, prompting parallels with the endoplasmic-reticulum-associated degradation pathway. Peroxisome membrane proteins, some of which are imported post-translationally, others of which may traffic to peroxisomes via the endoplasmic reticulum, use distinct proteinaceous machinery. The isolation of mutants defective in peroxisome biogenesis has served to emphasize the important role of peroxisomes at all stages of the plant life cycle.
authors.affiliation: Centre for Plant Sciences, University of Leeds, Leeds LS2 9JT, UK. a.baker@leeds.ac.uk
authors.forename: Alison
authors.initials: A
authors.lastname: Baker
authors.forename: Imogen A
authors.initials: IA
authors.lastname: Sparkes
authors.forename: Laura-Anne
authors.initials: LA
authors.lastname: Brown
authors.forename: Catherine
authors.initials: C
authors.lastname: O'Leary-Steele
authors.forename: Stuart L
authors.initials: SL
authors.lastname: Warriner
mesh_terms: D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D010084:Oxidation-Reduction; D020675:Peroxisomes / Q000378:metabolism* / Q000648:ultrastructure; D059828:Plant Cells; D010940:Plant Proteins / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
chemical_list: D005227:Fatty Acids; D008565:Membrane Proteins; D010940:Plant Proteins