title: Aseptic meningitis in adult onset Still's disease.
abstract: Adult onset Still's disease (AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy, and a neutrophilic leukocytosis. Though systemic complications of AOSD or its treatment are well described in the literature, CNS involvement in AOSD is exceedingly rare and can have protean manifestations. We present a patient with AOSD who developed chronic meningitis and sensorineural hearing loss on treatment, with a review of prior reported cases of aseptic meningitis, to highlight this rare complication of this uncommon illness.
authors.affiliation: Division of Rheumatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. akkaraveetil.bharathmanu@mayo.edu
authors.forename: Bharath Manu
authors.initials: BM
authors.lastname: Akkara Veetil
authors.forename: Alan H
authors.initials: AH
authors.lastname: Yee
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Warrington
authors.forename: Allen J
authors.initials: AJ
authors.lastname: Aksamit
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Mason
mesh_terms: D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008582:Meningitis, Aseptic / Q000209:etiology*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D016706:Still's Disease, Adult-Onset / Q000150:complications* / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents; D011241:Prednisone; D008727:Methotrexate