Partitioning of persistent organic pollutants between blubber and blood of wild bottlenose dolphins: implications for biomonitoring and health.
Biomonitoring surveys of wild cetaceans commonly utilize blubber as a means to assess exposure to persistent organic pollutants (POPs), but the relationship between concentrations in blubber and those in blood, a better indicator of target organ exposure, is poorly understood. To define this relationship, matched blubber and plasma samples (n = 56) were collected from free-ranging bottlenose dolphins (Tursiops truncatus) and analyzed for 61 polychlorinated biphenyl (PCB) congeners, 5 polybrominated diphenyl ether (PBDE) congeners, and 13 organochlorine pesticides (OCPs). With the exception of PCB 209, lipid-normalized concentrations of the major POPs in blubber and plasma were positively and significantly correlated (R(2) = 0.828 to 0.976). Plasma concentrations, however, significantly increased with declining blubber lipid content, suggesting that as lipid is utilized, POPs are mobilized into blood. Compound- and homologue- specific blubber/blood partition coefficients also differed according to lipid content, suggesting POPs are selectively mobilized from blubber. Overall, these results suggest that with the regression parameters derived here, blubber may be used to estimate blood concentrations and vice versa. Additionally, the mobilization of lipid from blubber and concomitant increase in contaminants in blood suggests cetaceans with reduced blubber lipid may be at greater risk for contaminant-associated health effects.
Yordy
Jennifer E
JE
Hollings Marine Laboratory, National Institute of Standards and Technology, 331 Fort Johnson Road, Charleston, South Carolina 29412, USA. jennifer.yordy@noaa.gov
Wells
Randall S
RS
Balmer
Brian C
BC
Schwacke
Lori H
LH
Rowles
Teri K
TK
Kucklick
John R
JR
D000825:Animal Structures / Q000378:metabolism*; D000818:Animals; D050681:Bottle-Nosed Dolphin / Q000097:blood*; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D006262:Health; D008055:Lipids / Q000032:analysis; D008297:Male; D009930:Organic Chemicals / Q000097:blood*; D012044:Regression Analysis; D014018:Tissue Distribution
D004785:Environmental Pollutants; D008055:Lipids; D009930:Organic Chemicals