Medication effects on sleep.
The understanding of the neuropharmacologic reciprocal interactions between the sleep and wake cycles has progressed significantly in the past decade. It was also recently appreciated that sleep disruption or deprivation can have adverse metabolic consequences. Multiple medications have a direct or indirect impact on sleep and the waking state. This article reviews how commonly prescribed medications can significantly affect the sleep-wake cycle.
Roux
Francoise J
FJ
Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, 333 Cedar Street, Post Office Box 208057, New Haven, CT 06520-8057, USA. francoise.roux@yale.edu
Kryger
Meir H
MH
D000978:Antiparkinson Agents / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000494:pharmacology; D001559:Benzhydryl Compounds / Q000494:pharmacology; D001569:Benzodiazepines / Q000494:pharmacology; D006633:Histamine Antagonists / Q000494:pharmacology; D006801:Humans; D008094:Lithium / Q000494:pharmacology; D000077408:Modafinil; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology; D014851:Wakefulness / Q000502:physiology
D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D001559:Benzhydryl Compounds; D001569:Benzodiazepines; D006633:Histamine Antagonists; D008094:Lithium; D000077408:Modafinil; D017367:Selective Serotonin Reuptake Inhibitors; D013806:Theophylline