title: A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation.
authors.affiliation: Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, SC 29208, USA.
authors.forename: Obiamaka
authors.initials: O
authors.lastname: Obianyo
authors.forename: Corey P
authors.initials: CP
authors.lastname: Causey
authors.forename: Tanesha C
authors.initials: TC
authors.lastname: Osborne
authors.forename: Justin E
authors.initials: JE
authors.lastname: Jones
authors.forename: Young-Ho
authors.initials: YH
authors.lastname: Lee
authors.forename: Michael R
authors.initials: MR
authors.lastname: Stallcup
authors.forename: Paul R
authors.initials: PR
authors.lastname: Thompson
mesh_terms: D000578:Amidines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001120:Arginine / Q000378:metabolism*; D020134:Catalytic Domain; D002460:Cell Line; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008745:Methylation; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011484:Protein-Arginine N-Methyltransferases / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D000578:Amidines; D004791:Enzyme Inhibitors; D010455:Peptides; D001120:Arginine; D011484:Protein-Arginine N-Methyltransferases