Indirect laser treatment and anti-VEGF therapy of a retinal angioma, with resolution of a large serous retinal detachment, macular exudates, and macular edema.
OBJECTIVE
To report on a novel treatment strategy in an eye with a retinal angioma and macular edema


METHODS
Wide-angle angiography was used to characterize the lesion and response to theraphy, while the treatment combined laser photocoagulation with the indirect laser delivery system, and intravitreal injections of pegaptanib and bevacizumab. Treatment was rendered over 21 months' time.


RESULTS
The treatment resulted in graduate resolution of marked macular edema and exudation, with a gain in visual acuity.


CONCLUSIONS
A combination of laser photocoagulation and anti-VEGF theraphy can be effective in the treatment of macular exudation and edema from a retinal angioma.
Rarey
Kristin
K
UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Friberg
Thomas R
TR
D000368:Aged; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D052157:Aptamers, Nucleotide / Q000627:therapeutic use; D000068258:Bevacizumab; D003131:Combined Modality Therapy; D005122:Exudates and Transudates; D005260:Female; D005451:Fluorescein Angiography; D006391:Hemangioma / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D017075:Laser Coagulation; D008269:Macular Edema / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D012163:Retinal Detachment / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D041623:Tomography, Optical Coherence; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*; D014792:Visual Acuity / Q000502:physiology
D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D052157:Aptamers, Nucleotide; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; C495058:pegaptanib; D000068258:Bevacizumab