title: A unique protein labeling system based on melittin and the non-covalent  binding-induced pyrene excimer.
abstract: We report a unique protein labeling system based on melittin and a pyrene derivative (1). The specific region of the C-terminal in melittin efficiently induced the formation of the pyrene eximer, which can be used as a tag to target proteins and for further detection.
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, 130012, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Li
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Li
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Ma
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Dang
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000595:Amino Acid Sequence; D002942:Circular Dichroism; D008555:Melitten / Q000737:chemistry*; D008969:Molecular Sequence Data; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013194:Staining and Labeling / Q000379:methods*; D014364:Tryptophan / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: C551637:N-(4-(1-pyrene)butyroyl)tryptophan; D011721:Pyrenes; D008555:Melitten; D014364:Tryptophan