title: Three new dioxopiperazine metabolites from a marine-derived fungus Aspergillus fumigatus Fres.
abstract: Three new dioxopiperazine metabolites (1-3), together with two known compounds, N-acetyltyramine (4) and cyclo-(Ala-Val) (5), were isolated from a marine-derived fungus Aspergillus fumigatus Fres. Their structures were established by spectroscopic methods. Their cytotoxic activities against the K562 cell line were preliminarily evaluated by the sulphorhodamine B (SRB) method.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, PR China.
authors.forename: Wen Ying
authors.initials: WY
authors.lastname: Zhao
authors.forename: Tian Jiao
authors.initials: TJ
authors.lastname: Zhu
authors.forename: Guo Tao
authors.initials: GT
authors.lastname: Fan
authors.forename: Hong Bing
authors.initials: HB
authors.lastname: Liu
authors.forename: Yu Chun
authors.initials: YC
authors.lastname: Fang
authors.forename: Qian Qun
authors.initials: QQ
authors.lastname: Gu
authors.forename: Wei Ming
authors.initials: WM
authors.lastname: Zhu
mesh_terms: D001232:Aspergillus fumigatus / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D000077489:Piperazine; D010879:Piperazines / Q000737:chemistry*
chemical_list: D010879:Piperazines; D000077489:Piperazine