Five sesquiterpenoids from a marine-derived fungus Aspergillus sp. isolated from a gorgonian Dichotella gemmacea.
Three new phenolic bisabolane-type sesquiterpenoids: (+)-methyl sydowate (1), 7-deoxy-7,14-didehydrosydonic acid (2), and 7-deoxy-7,8-didehydrosydonic acid (3), together with two known fungal metabolites were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated in turn from a gorgonian Dichotella gemmacea collected from the South China Sea. Their structures were elucidated by combined spectroscopic methods, and the structure of 1 was further confirmed by single-crystal X-ray data.
Wei
Mei-Yan
MY
School of Pharmacy, Guangdong Medical College, Dongguan, 523808, China. mywei95@126.com
Wang
Chang-Yun
CY
Liu
Qing-Ai
QA
Shao
Chang-Lun
CL
She
Zhi-Gang
ZG
Lin
Yong-Cheng
YC
D000818:Animals; D037421:Anthozoa / Q000382:microbiology*; D001230:Aspergillus / Q000737:chemistry* / Q000302:isolation & purification; D002681:China; D018360:Crystallography, X-Ray; D005285:Fermentation; D012623:Seawater; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D013057:Spectrum Analysis
D012717:Sesquiterpenes