title: Composition and biological properties of the volatile oil of Artemisia gorgonum Webb.
abstract: The chemical composition of Artemisia gorgonum Webb essential oil from Cape Verde was analyzed by GC and GC/MS. A total of 111 volatile compounds, accounting for 94.9% of the essential oil, were identified by GC and GC/MS. The major compounds were camphor (28.7%), chrysanthenone (10.8%), lavandulyl 2-methylbutanoate (9.5%), alpha-phellandrene (5.5%), lavandulyl propanoate (4.2%), camphene (4.0%), and p-cymene (3.4%). The volatile oil of this endemic plant, which is used in Cape Verdean folk medicine against several ailments, was tested for its antioxidant and antimalarial properties, and was found to exhibit free-radical scavenging on 1,1-diphenyl-2-picrylhydrazyl (DPPH), prevention of lipid peroxidation-in vitro by TBARS (thiobarbituric acid reactive species) assay, and antiplasmodial activity.
authors.affiliation: Université de Nice-Sophia Antipolis, Laboratoire de Chimie des Molécules Bioactives et des Arômes, UMR 6001 CNRS, Faculté des Sciences, 28 Avenue Valrose, F-06108 Nice Cedex 2.
authors.forename: Risoleta
authors.initials: R
authors.lastname: Ortet
authors.forename: Olivier P
authors.initials: OP
authors.lastname: Thomas
authors.forename: Erik L
authors.initials: EL
authors.lastname: Regalado
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Pino
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Filippi
authors.forename: Miguel D
authors.initials: MD
authors.lastname: Fernández
mesh_terms: D000962:Antimalarials / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D019306:Artemisia / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D015227:Lipid Peroxidation / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*
chemical_list: D000962:Antimalarials; D016166:Free Radical Scavengers; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils