Amyloid A amyloidosis and systemic lupus erythematosus.
Amyloid A (AA) amyloidosis occurs secondary to long-standing inflammation and causes nephropathy and various internal manifestations, which leads to mortality. It is very rare in some rheumatic diseases, such as systemic lupus erythematosus (SLE). Therefore, there are few articles that report AA amyloidosis in SLE. This article focuses on the previously reported cases of 24 patients with SLE that are complicated by AA amyloidosis, and on the underlying mechanisms.
Düzgün
Nursen
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Ankara University Faculty of Medicine, Department of Clinical Immunology and Rheumatology, Samanpazar, 06100 Ankara, Turkey. duzgun@medicine.ankara.edu.tr