title: Iron(II)-bis(isonitrile) complexes: novel catalysts in asymmetric transfer hydrogenations of aromatic and heteroaromatic ketones.
abstract: Chiral iron(ii)-bis(isonitrile) complexes catalyse the transfer hydrogenation of aromatic ketones with enantioselectivities up to 91% ee, most likely via hydride transfer through imine intermediates, generated by in situ reduction of the isonitrile ligands, whereas iron acts as a Lewis acid to activate the ketone.
authors.affiliation: Institut für Organische Chemie, Universität Regensburg, Universitätsstr. 31, 93053 Regensburg, Germany.
authors.forename: Anu
authors.initials: A
authors.lastname: Naik
authors.forename: Tapan
authors.initials: T
authors.lastname: Maji
authors.forename: Oliver
authors.initials: O
authors.lastname: Reiser
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D005296:Ferrous Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*
chemical_list: D005296:Ferrous Compounds; D007659:Ketones; D009570:Nitriles