title: Transpalpebral measurement of intraocular pressure using the Diaton tonometer versus standard Goldmann applanation tonometry.
abstract: BACKGROUND
  Diaton transpalpebral tonometry is a new version of TGDc-01 transpalpebral tonometry. The aim of this study is to evaluate the reliability of this method, and to compare the results with those of corrected Goldmann applanation tonometry (c-GAT), which is the "gold standard" for the clinical measurement of IOP.
  
  
  METHODS
  IOP was measured in 212 eyes of 129 subjects by means of two different methods. Measurements with two tonometers were performed in random order, and the measurements of central cornea thickness were performed with ultrasound pachymetry.
  
  
  RESULTS
  The average IOP reading was 15.46 ± 5.68 mmHg for c-GAT and 13.84 ± 5.12 mmHg for Diaton tonometer. The mean difference between c-GAT and Diaton tonometer was 1.62 ± 3.60 mmHg (p < 0.05). Compared with c-GAT, 39.6% of IOP readings (84 eyes) by Diaton tonometer was in an interval of ± 1 mmHg; 59.4% (126 eyes) was in an interval of ± 2 mmHg, and 76.4% (162 eyes) was in an interval of ± 3 mmHg. For the subjects whose age was from 20 to 50, the mean difference of IOP readings by two tonometers was 0.53 ± 3.24 mmHg.
  
  
  CONCLUSIONS
  We cannot recommend Diaton as a substitute or alternative method for GAT for diagnosis and follow-up of patients with abnormal IOPs, but it may be helpful as a screening tool, especially for subjects whose age is between 20 and 50 years and for healthy subjects.
authors.affiliation: Department of Ophthalmology, 2nd Xiang-Ya Hospital, Central South University, Changsha, 410011, People's Republic of China. liyuehua501@yahoo.com.cn
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Li
authors.forename: Jingming
authors.initials: J
authors.lastname: Shi
authors.forename: Xuanchu
authors.initials: X
authors.lastname: Duan
authors.forename: Fang
authors.initials: F
authors.lastname: Fan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003315:Cornea / Q000033:anatomy & histology; D005143:Eyelids; D005260:Female; D005901:Glaucoma / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D015203:Reproducibility of Results; D014065:Tonometry, Ocular / Q000295:instrumentation*; D055815:Young Adult