Influence of titanium implant surface characteristics on bone regeneration in dehiscence-type defects: an experimental study in dogs.
OBJECTIVE
The aim of the present study was to compare bone regeneration in dehiscence-type defects at titanium implants with chemically modified sandblasted/acid-etched (modSLA) or dual acid-etched surfaces with a calcium phosphate nanometre particle modification (DCD/CaP).


METHODS
Buccal dehiscence-type defects were surgically created following implant site preparation in both the upper and the lower jaws of 12 fox hounds. Both types of implants were randomly allocated in a split-mouth design and left to heal in a submerged position for 2 and 8 weeks. Dissected blocks were processed for histomorphometrical analysis [e.g. new bone height (NBH), percentage of bone-to-implant contact (BIC), area of new bone fill (BF), and area of mineralized tissue (MT) within BF].


RESULTS
At 2 and 8 weeks, both groups revealed comparable mean BF (2.3+/-0.6 to 2.5+/-0.6 mm(2)versus 2.0+/-0.6 to 1.4+/-0.5 mm(2)) and MT (31.1+/-14.3-83.2+/-8.2%versus 38.9+/-15.9-84.4+/-6.3%) values. However, modSLA implants revealed significantly higher mean NBH (2.4+/-0.8 to 3.6+/-0.3 mm versus 0.9+/-0.8 to 1.8+/-1.4 mm) and BIC (53.3+/-11.3-79.5+/-6.6%versus 19.3+/-16.4-47.2+/-30.7%) values than DCD/CaP implants.


CONCLUSIONS
ModSLA implants may have a higher potential to support osseointegration in dehiscence-type defects than DCD/CaP implants.
Schwarz
Frank
F
Department of Oral Surgery, Westdeutsche Kieferklinik, Germany. frank.schwarz@med.uni-dueseldorf.de
Sager
Martin
M
Kadelka
Ines
I
Ferrari
Daniel
D
Becker
Jürgen
J
D000134:Acid Etching, Dental / Q000379:methods*; D000818:Animals; D002130:Calcium Phosphates; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D004285:Dogs; D053758:Nanoparticles; D016348:Osseointegration; D011897:Random Allocation; D013499:Surface Properties; D013529:Surgical Wound Dehiscence; D014025:Titanium
D002130:Calcium Phosphates; D015921:Dental Implants; C020243:calcium phosphate; D014025:Titanium