title: The role of endorectal magnetic resonance imaging in predicting extraprostatic extension and seminal vesicle invasion in clinically localized prostate cancer.
abstract: OBJECTIVE
  We aimed to assess the clinical value of endorectal magnetic resonance imaging (MRI) in predicting extraprostatic extension and seminal vesicle invasion in patients with clinically localized prostate cancer.
  
  
  METHODS
  A total of 54 patients who underwent radical prostatectomy for clinically localized prostate cancer were retrospectively analyzed. The findings of endorectal MRI, performed at least 3 weeks after biopsy, were compared with the pathological results of radical prostatectomy specimens. The sensitivity, specificity, and accuracy of the detection of extraprostatic extension and seminal vesicle invasion were calculated.
  
  
  RESULTS
  The sensitivity, specificity, and accuracy of the endorectal MRI findings were 50.0%, 82.6%, and 77.8% for the detection of extraprostatic extension, respectively, and 75.0%, 92.0%, and 90.7% for the detection of seminal vesicle invasion, respectively. The sensitivity of endorectal MRI in the detection of extraprostatic extension improved as the Gleason score increased.
  
  
  CONCLUSIONS
  Endorectal MRI findings demonstrated modest sensitivity for predicting extraprostatic extension, whereas specificity was relatively high. In addition, endorectal MRI showed better sensitivity for detecting high-grade tumors.
authors.affiliation: Department of Urology, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Seo Yong
authors.initials: SY
authors.lastname: Park
authors.forename: Jung Jun
authors.initials: JJ
authors.lastname: Kim
authors.forename: Tae Heon
authors.initials: TH
authors.lastname: Kim
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Lim
authors.forename: Deok Hyun
authors.initials: DH
authors.lastname: Han
authors.forename: Byung Kwan
authors.initials: BK
authors.lastname: Park
authors.forename: Chan Kyo
authors.initials: CK
authors.lastname: Kim
authors.forename: Ghee Young
authors.initials: GY
authors.lastname: Kwon
authors.forename: Han Yong
authors.initials: HY
authors.lastname: Choi
authors.forename: Hyun Moo
authors.initials: HM
authors.lastname: Lee