Vibrational and electronic characterisation of Staphylococcus aureus wall teichoic acids and relevant components in thin films.
This work reports an investigation of S. aureus wall teichoic acid (WTA) and compares this biopolymer with its major occurring components, D: -alanine and glycerol phosphate. Detailed insight into molecular structures and electronic properties is obtained by vibrational and photoemission spectroscopy. Calculations are performed to support the analysis of our experimental vibrational spectra. It is shown that there are contributions of positive and negative charges in WTAs, but the number of negative charges is expected to be higher. The presence of both positive and negative charges on WTA may offer a route for modification of surfaces with the objective of avoiding the formation of biofilms.
Latteyer
Florian
F
Institute for Physical and Theoretical Chemistry, Auf der Morgenstelle 18, 72076 Tübingen, Germany. florian.latteyer@uni-tuebingen.de
Peisert
Heiko
H
Göhring
Nadine
N
Peschel
Andreas
A
Chassé
Thomas
T
D000409:Alanine; D002473:Cell Wall / Q000737:chemistry; D005994:Glycerophosphates; D007477:Ions; D015394:Molecular Structure; D056951:Photoelectron Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000737:chemistry*; D013682:Teichoic Acids / Q000737:chemistry*
D005994:Glycerophosphates; D007477:Ions; D013682:Teichoic Acids; D000409:Alanine