title: Outcomes of fat injection laryngoplasty in unilateral vocal cord paralysis.
abstract: OBJECTIVE
  To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis.
  
  
  METHODS
  Longitudinal outcomes evaluation study.
  
  
  METHODS
  Tertiary referral voice center.
  
  
  METHODS
  Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan.
  
  
  METHODS
  Autologous fat injection laryngoplasty.
  
  
  METHODS
  Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey.
  
  
  RESULTS
  Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P < .05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning-physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery.
  
  
  CONCLUSIONS
  Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.
authors.affiliation: Department of Otolaryngology, Chang Gung Memorial Hospital, Keelung, Taiwan.
authors.forename: Tuan-Jen
authors.initials: TJ
authors.lastname: Fang
authors.forename: Hsueh-Yu
authors.initials: HY
authors.lastname: Li
authors.forename: Richard E
authors.initials: RE
authors.lastname: Gliklich
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Chen
authors.forename: Pa-Chun
authors.initials: PC
authors.lastname: Wang
authors.forename: Hsiu-Feng
authors.initials: HF
authors.lastname: Chuang
mesh_terms: D000273:Adipose Tissue; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010699:Phonation; D011788:Quality of Life; D013061:Speech Acoustics; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000628:therapy*