title: High prevalence of a novel porcine bocavirus in weanling piglets with respiratory tract symptoms in China.
abstract: This study presents the first evidence of infection by a novel porcine bocavirus (PBoV) in Chinese swine herds. The PCR detection results showed that PBoV was significantly more prevalent in weanling piglets (69.7%, 69/99) with respiratory tract symptoms than that in other samples (0-13.6%) (P < 0.01). Sequence analysis showed that the partial VP1/2 genes were highly conserved (99-100% identity), and only five frequent nucleotide mutation positions existed in Chinese PBoV strains. These data indicate that PBoV might be an emerging virus for swine respiratory tract diseases. This study could help us to better understand the epidemiology of PBoV.
authors.affiliation: Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Aricultural Sciences, No. 518 Ziyue Road, Minhang District, Shanghai 200241, China.
authors.forename: Shaolun
authors.initials: S
authors.lastname: Zhai
authors.forename: Cheng
authors.initials: C
authors.lastname: Yue
authors.forename: Zuzhang
authors.initials: Z
authors.lastname: Wei
authors.forename: Jinxue
authors.initials: J
authors.lastname: Long
authors.forename: Duoliang
authors.initials: D
authors.lastname: Ran
authors.forename: Tao
authors.initials: T
authors.lastname: Lin
authors.forename: Yu
authors.initials: Y
authors.lastname: Deng
authors.forename: Lv
authors.initials: L
authors.lastname: Huang
authors.forename: Lichang
authors.initials: L
authors.lastname: Sun
authors.forename: Haihong
authors.initials: H
authors.lastname: Zheng
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.forename: Hao
authors.initials: H
authors.lastname: Zheng
authors.forename: Shengnan
authors.initials: S
authors.lastname: Chen
authors.forename: Shishan
authors.initials: S
authors.lastname: Yuan
mesh_terms: D000818:Animals; D001483:Base Sequence; D052660:Bocavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D002681:China; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012137:Respiratory System / Q000821:virology; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D014886:Weaning