Benign monoclonal gammopathy-associated acute kidney injury: case report and literature review.
BACKGROUND
Benign monoclonal gammopathy (MG) is an MG that is not accompanied by clinical manifestations of plasma cell dyscrasia, such as multiple myeloma, macroglobulinemia, amyloidosis, or other related disorders. Benign MG can progress to malignancy, but seldom causes organ damage.


METHODS
We presented a case denied any underlying disease who visited our hospital as acute uremia syndrome. Laboratory data indicated renal failure and abnormal paraprotein in the serum and urine. Renal biopsy indicated acute tubular necrosis and cast in the renal tubule. The plasma cell counts were normal in his bone marrow biopsy. The patient had received maintenance hemodialysis for the irreversible renal failure.


CONCLUSIONS
Benign MG might progress to malignancy or other related disorders in a risk of 1% per year. It also might cause secondary organ impairment, such as kidney.
Hii
Ing Moi
IM
Nephrology Division, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, Republic of China.
Chen
Mei Ling
ML
Chang
Chia-Chu
CC
D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D006801:Humans; D008297:Male; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000150:complications*