title: A new fine-needle aspiration system.
abstract: BACKGROUND
  The main reasons for fine needle aspiration (FNA) failure are insufficient number of cells in the sample, nonrepresentative samples, and contamination of samples. The aim of this study was to measure the number of cells harvested by a new needle system with an aeration aperture (Thyrosampler) in comparison with a conventional FNA system (C-FNA).
  
  
  METHODS
  Under a double-blind setting, 30 aspirations, 15 with each system (C-FNA, Thyrosampler), were done in randomized order and recorded.
  
  
  RESULTS
  The median total number of cells was 59 680 cells/mL with C-FNA and 396 400 cells/mL with Thyrosampler. The needle system with the aeration aperture led to a significantly higher cell amount (564% more cells than the conventional system; P < .005) in needle aspiration biopsy.
  
  
  CONCLUSIONS
  The new system with the vacuum release feature leads to a significantly higher cell amount in needle aspiration biopsy, which is a well-defined benefit.
authors.affiliation: Medical University of Graz, Graz, Austria. mathias.glehr@klinikum-graz.at
authors.forename: Mathias
authors.initials: M
authors.lastname: Glehr
authors.forename: Andreas
authors.initials: A
authors.lastname: Leithner
authors.forename: Gerald
authors.initials: G
authors.lastname: Gruber
authors.forename: Paul
authors.initials: P
authors.lastname: Wretschitsch
authors.forename: Maximilian
authors.initials: M
authors.lastname: Zacherl
authors.forename: Thomas
authors.initials: T
authors.lastname: Kroneis
authors.forename: Franz
authors.initials: F
authors.lastname: Quehenberger
authors.forename: Reinhard
authors.initials: R
authors.lastname: Windhager
mesh_terms: D000818:Animals; D044963:Biopsy, Fine-Needle / Q000295:instrumentation*; D002452:Cell Count; D002470:Cell Survival; D004311:Double-Blind Method; D023421:Models, Animal; D013552:Swine; D013961:Thyroid Gland / Q000473:pathology*; D014618:Vacuum