The cognitive profile of preschool-aged children with neurofibromatosis type 1.
Few studies have examined the cognitive profile of young children with NF1. In this study, 26 children with NF1 (M(age) = 5 years 3 months) were compared with 21 peer comparisons (M(age) = 4 years 8 months) and available normative data on neuropsychological measures. Children with NF1 demonstrated the characteristic downward shift in IQ, poor visuospatial constructional skills, and inattention. Working memory deficits were common in parental ratings. These findings suggest that at least some of the cognitive deficits associated with NF1 can be identified in the preschool-age group, highlighting the need for early assessment and intervention.
Sangster
Jennifer
J
Department of Psychology, Macquarie University, New South Wales, Australia.
Shores
E Arthur
EA
Watt
Sharon
S
North
Kathryn N
KN
D001288:Attention; D016022:Case-Control Studies; D002675:Child, Preschool; D003071:Cognition; D005260:Female; D006801:Humans; D007360:Intelligence; D007361:Intelligence Tests; D008297:Male; D008570:Memory, Short-Term; D009456:Neurofibromatosis 1 / Q000523:psychology*; D009483:Neuropsychological Tests; D013037:Spatial Behavior; D014796:Visual Perception