title: Desmoplastic fibroma of the cervical spine: case report and review of the literature.
abstract: METHODS
  A case report and literature review are presented.
  
  
  OBJECTIVE
  To present a rare case of desmoplastic fibroma (DF) in the cervical spine and discuss the diagnosis and treatment of this disorder.
  
  
  BACKGROUND
  DF is an extremely rare primary tumor of bone, especially in cervical spine. It is a benign but locally aggressive tumor of the connective tissue. It has a predilection for the mandible and the metadiaphyses of long bones. It has a propensity for local recurrence, especially after intralesional resection.
  
  
  METHODS
  We report on a 70-year-old woman with a DF of the fourth and fifth cervical vertebrae. The patient complained of progressive neck pain and limitation of activity. After radiologic evaluation, a mass lesion was found on the fourth and fifth cervical vertebral bodies. A 2-level corpectomy with wide marginal resection of the tumor was performed through the anterior approach, and the histopathologic examination yielded the diagnosis of DF. Reconstruction was achieved with a long titanium mesh and locking plate with autologous iliac crest bone graft.
  
  
  RESULTS
  After surgery, pain was completely relieved, and neurologic function was normal. The postoperative course was uneventful, and the patient has been well without recurrence for 35 months of follow-up evaluation.
  
  
  CONCLUSIONS
  Patients with DF of the cervical spine may present with the arm and neck pain mimicking cervical disc disease. High index of suspicion by the clinicians must be practiced to make the appropriate diagnosis, and histologic confirmation of the diagnosis is essential. Surgical resection with wide margins is the preferred treatment.
authors.affiliation: Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Ni
authors.forename: Liangyu
authors.initials: L
authors.lastname: Zhao
authors.forename: Huajiang
authors.initials: H
authors.lastname: Chen
authors.forename: Songkai
authors.initials: S
authors.lastname: Li
authors.forename: Fengjin
authors.initials: F
authors.lastname: Zhou
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: Nicholas
authors.initials: N
authors.lastname: Tsai
mesh_terms: D000368:Aged; D002574:Cervical Vertebrae; D005260:Female; D018220:Fibroma, Desmoplastic / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome