title: Ebstein's anomaly in pregnancy: maternal and neonatal outcomes.
abstract: OBJECTIVE
  Ebstein's anomaly is a rare congenital cardiac abnormality, associated with cyanosis and arrhythmia. Patients often reach childbearing age and pregnant women pose a challenge to the treating physician. We describe the course and outcome of pregnancy in women with Ebstein's anomaly and discuss the related management issues.
  
  
  METHODS
  Analysis of pregnancies in four women with Ebstein's anomaly was carried out in a referral institute in northern India. Data of two women were analyzed retrospectively and the other two women were prospectively followed in their pregnancies during the study period. The course of the pregnancy, disease and perinatal outcome in each woman were analyzed.
  
  
  RESULTS
  Four women had eight pregnancies all resulting in vaginal deliveries. There were two premature deliveries. The mean birth weight was 2.54 + or - 0.88 kg. Of the eight babies, six did not have any cardiac anomalies; one was an unexplained neonatal death and for another, no data was available. Pregnancy was well tolerated in two patients, while one had right heart failure during early pregnancy, and one had arrhythmia during labor, which was managed medically; one patient had arrhythmia in the postpartum period, which was managed medically.
  
  
  CONCLUSIONS
  When a woman with Ebstein's anomaly reaches childbearing age, fertility is not affected, even in cyanotic women. Under close supervision by the woman's obstetrician and cardiologist, the pregnancy outcome is usually favorable.
authors.affiliation: Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. drseemachopra@yahoo.com
authors.forename: Seema
authors.initials: S
authors.lastname: Chopra
authors.forename: Vanita
authors.initials: V
authors.lastname: Suri
authors.forename: Neelam
authors.initials: N
authors.lastname: Aggarwal
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Rohilla
authors.forename: Rajesh
authors.initials: R
authors.lastname: Vijayvergiya
authors.forename: Anish
authors.initials: A
authors.lastname: Keepanasseril
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000000981:diagnostic imaging*; D001724:Birth Weight; D003490:Cyanosis / Q000150:complications / Q000000981:diagnostic imaging*; D036861:Delivery, Obstetric; D004437:Ebstein Anomaly / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging*; D011256:Pregnancy Outcome; D011446:Prospective Studies; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D014463:Ultrasonography