Bronchoscopic management of sarcoidosis related bronchial stenosis with adjunctive topical mitomycin C.
A 58-year-old woman with multiple proximal airway stenoses due to sarcoidosis failed to improve with steroid therapy. After bronchoscopic balloon dilation with adjunctive topical mitomycin C, there was symptomatic improvement and preserved patency of the airways one month later. However, the patient's effort tolerance gradually deteriorated subsequently, and a repeat bronchoscopy one year later showed recurrence of airway stenosis.
Teo
Felicia
F
Division of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Anantham
Devanand
D
Feller-Kopman
David
D
Ernst
Armin
A
D000287:Administration, Topical; D001982:Bronchial Diseases / Q000209:etiology* / Q000628:therapy*; D001999:Bronchoscopy; D017024:Chemotherapy, Adjuvant; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D019384:Nucleic Acid Synthesis Inhibitors / Q000008:administration & dosage*; D017565:Sarcoidosis, Pulmonary / Q000150:complications*
D019384:Nucleic Acid Synthesis Inhibitors; D016685:Mitomycin