[Optical coherence tomography for evaluation of neointimal proliferation after placement of a new drug eluting stent].
OBJECTIVE
To evaluate neointimal proliferation following placement of a new drug-eluting stent (BUMA) by optical coherence tomography (OCT).


METHODS
Twenty-two patients with coronary artery disease were randomized into BUMA group (n=15) and Endeavor group (n=7) and underwent OCT imaging after 9 months of stent implantation.


RESULTS
The neointima hyperplasia (NIH) thickness in BUMA group were significantly smaller than that in endeavor group (0.220-/+0.140 mm vs 0.269-/+0.207 mm, P<0.001), and the uncovered Struts were significantly lower in BUMA group than in Endeavor group (5.65% vs 6.56%, P<0.0001). The luminal late loss in BUMA group was also significantly lower (34.87-/+11.50 vs 40.82-/+18.53, P=0.025).


CONCLUSIONS
BUMA stent is safe and effective for treatment of coronary artery disease.
Liu
Chang-fu
CF
Department of Cardiology, General Hospital of PLA, Beijing 100853, China. liucf301@126.com
Chen
Yun-dai
YD
Chen
Lian
L
Sun
Zhi-jun
ZJ
Gai
Lu-yue
LY
Liu
Hong-bin
HB
Tian
Feng
F
Bai
Qi-cai
QC
Guo
Kai
K
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D049109:Cell Proliferation; D003324:Coronary Artery Disease / Q000473:pathology / Q000628:therapy*; D003331:Coronary Vessels / Q000473:pathology*; D054855:Drug-Eluting Stents / Q000009:adverse effects; D006801:Humans; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D017539:Tunica Intima / Q000473:pathology*