title: Linear scleroderma after contusion and injection of mepivacaine hydrochloride.
abstract: A 36-year-old woman initially was treated for a contusion by local injection of mepivacaine hydrochloride into the left dorsum of the foot. Approximately 3 months after the injury and injection, linear sclerotic plaques originating from the site of contusion and injection were recognized. These progressed in extent and severity over a period of 3 years, when she presented to our clinic. By biopsy, swelling of collagen fibers in the lower dermis was revealed and the condition was diagnosed as linear scleroderma. Our present case had multiple linear sclerotic plaques of the left lower extremity, the distribution of which was consistent with Blaschko lines. It was also revealed that the initial sclerotic plaque was at the site of the contusion and local mepivacaine hydrochloride injection. Our present case is interesting in that the findings suggest a correlation between linear scleroderma plaque occurrence and the contusion or injection of mepivacaine.
authors.affiliation: Department of Dermatology, Kitasato University. School of Medicine, Sagamihara, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ueda
authors.forename: Shiro
authors.initials: S
authors.lastname: Niiyama
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Amoh
authors.forename: Kensei
authors.initials: K
authors.lastname: Katsuoka
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D003288:Contusions / Q000150:complications*; D005260:Female; D018409:Foot Injuries / Q000150:complications*; D006801:Humans; D007267:Injections; D007868:Leg Dermatoses / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D008619:Mepivacaine / Q000008:administration & dosage / Q000009:adverse effects*; D012594:Scleroderma, Localized / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology
chemical_list: D000779:Anesthetics, Local; D008619:Mepivacaine