title: Mapping subchondral bone density of selected donor and recipient sites for autologous osteochondral transplantation in the canine stifle joint using computed tomographic osteoabsorptiometry.
abstract: OBJECTIVE
  To characterize donor and recipient sites for autologous osteochondral transplantation (AOT) in the canine stifle joint with respect to maximal subchondral bone density (mSBD).
  
  
  METHODS
  Descriptive laboratory study.
  
  
  METHODS
  Femora (n=15) of dogs (>20 kg).
  
  
  METHODS
  mSBD at selected donor sites within and outside the femoropatellar joint and at potential recipient sites for both femoral condyles was assessed using nonvolumetric computed tomographic osteoabsorptiometry and normalized to values obtained at the central weight-bearing aspect of the lateral femoral condyle.
  
  
  RESULTS
  Only transplants harvested at the axial aspects of the lateral and medial trochlear ridge had a normalized mSBD comparable with the lateral and medial femoral condyle. Grafts from outside the femoropatellar joint, at the most proximal aspect of the medial femoral condyle and at the most distal aspect of the trochlea (the notch area) had mSBD values 13.8-24.4% less than at the femoral condyles.
  
  
  CONCLUSIONS
  Choosing between donor sites within or outside the femoropatellar joint may significantly affect subchondral bone quality of harvested transplants.
  
  
  CONCLUSIONS
  Donor sites abaxial to the femoropatellar joint and at the most proximal aspect of the medial femoral condyle may provide transplants of suboptimal bone morphology, challenging their use as primary donor sites for AOT in dogs. However, this statement is based on nonvolumetric assessment of bone density, necessitating verification using volumetric density analysis to finally infer the biomechanical value of different grafts.
authors.affiliation: Department of Small Animal Medicine, University of Leipzig, Leipzig, Germany. boettcher@kleintierklinik.uni-leipzig.de
authors.forename: Peter
authors.initials: P
authors.lastname: Böttcher
authors.forename: Markus
authors.initials: M
authors.lastname: Zeissler
authors.forename: Vera
authors.initials: V
authors.lastname: Grevel
authors.forename: Gerhard
authors.initials: G
authors.lastname: Oechtering
authors.forename: Johann
authors.initials: J
authors.lastname: Maierl
mesh_terms: D000818:Animals; D015519:Bone Density; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005269:Femur / Q000033:anatomy & histology / Q000637:transplantation*; D010329:Patella / Q000033:anatomy & histology / Q000637:transplantation; D013264:Stifle / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000662:veterinary*; D014182:Transplantation, Autologous; D016474:Weight-Bearing