title: Enantioselective Michael addition of ketones to maleimides catalyzed by bifunctional monosulfonyl DPEN salt.
abstract: An unprecedented enantioselective Michael addition of various ketones to maleimides catalyzed by a simple bifunctional primary amine, monosulfonyl DPEN salt, is reported and provides the desired adducts in good to excellent yields (up to 99%) with excellent enantioselectivities (up to 99%).
authors.affiliation: Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Yu
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Sun
authors.forename: Zhichao
authors.initials: Z
authors.lastname: Jin
authors.forename: Shigang
authors.initials: S
authors.lastname: Wen
authors.forename: Xinmiao
authors.initials: X
authors.lastname: Liang
authors.forename: Jinxing
authors.initials: J
authors.lastname: Ye
mesh_terms: D002384:Catalysis; D005029:Ethylenediamines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008301:Maleimides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012492:Salts / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D005029:Ethylenediamines; D007659:Ketones; D008301:Maleimides; D012492:Salts; C007305:1,2-dianilinoethane