title: [Primitive leptomeningeal malignant melanoma: a rare etiology of pachymeningitis and leptomeningitis].
abstract: BACKGROUND
  Leptomeningitis and pachymeningitis are known to occur consecutive to many causes.
  
  
  METHODS
  We report the case of a 24-year-old woman with symptoms of raised intracranial pressure and repeated switching transient hemiparesis. The magnetic resonance imaging (MRI) showed a pachyleptomeningitis. Search for a cause was negative. The pathology examination of meningeal tissue revealed a malignant melanoma, without any sign of cutaneous melanoma, leading to the diagnosis of primary leptomeningeal malignant melanoma.
  
  
  CONCLUSIONS
  A meningeal biopsy can enable the rare diagnosis of primary leptomeningeal malignant melanoma in a patient with unexplained pachyleptomeningitis.
authors.affiliation: Service de neurologie C, pôle de neurologie, hôpital Roger-Salengro, CHRU de Lille, 2, rue Emile-Laine, 59037 Lille cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Bocquillon
authors.forename: A-S
authors.initials: AS
authors.lastname: Berteloot
authors.forename: C-A
authors.initials: CA
authors.lastname: Maurage
authors.forename: M-A
authors.initials: MA
authors.lastname: Mackowiak-Cordoliani
authors.forename: F
authors.initials: F
authors.lastname: Pasquier
authors.forename: S
authors.initials: S
authors.lastname: Bombois
mesh_terms: D001706:Biopsy; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008577:Meningeal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008581:Meningitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D010291:Paresis / Q000209:etiology; D055815:Young Adult