[Recent progress of researches on scaffolds for tissue engineered meniscus].
Tissue engineered meniscus provides a novel approach for the treatment of severe meniscus injury. The researches on scaffold for tissue engineered meniscus is an essential element. The researches on scaffolds for tissue engineered meniscus, including natural biomaterials and synthetic polymer, have made great advances in recent years. At present, collagen meniscus implants have been used in clinical practice. As hydrogel is characterized by having high water content and good biocompatibility, being similar to extracellular matrix in structure, and being able to provide access to microsurgery, it has become the hotspot field in recent years. Meanwhile, the combinatorial scaffold material advantages of biological composite tissue engineered scaffolds also illuminate the key point of research on meniscal scaffolds. This paper reviews the recent progress in betterment of the scaffolds so as to provide a theoretical and practical basis for further researches of tissue engineered meniscus.
Fu
Weili
W
Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Wang
Jianyun
J
Wan
Changxiu
C
Li
Jian
J
D000818:Animals; D001672:Biocompatible Materials; D002478:Cells, Cultured; D019902:Chondrocytes / Q000166:cytology*; D006801:Humans; D020100:Hydrogels; D008592:Menisci, Tibial / Q000166:cytology / Q000601:surgery; D012038:Regeneration / Q000502:physiology; D000070600:Tibial Meniscus Injuries; D023822:Tissue Engineering; D054457:Tissue Scaffolds
D001672:Biocompatible Materials; D020100:Hydrogels