Kabuki syndrome and cancer in two patients.
Both hepatoblastoma and neuroblastoma are occasionally associated with congenital syndromes such as Beckwith-Wiedemann syndrome and trisomy 18. There have been no reports of hepatoblastoma in patients with Kabuki syndrome, whereas one patient with neuroblastoma and this syndrome has been reported. In this paper we present two patients with Kabuki syndrome and a neoplasm: a child of 6 years with hepatoblastoma and an infant, of 6 months affected by neuroblastoma.
Tumino
Manuela
M
Unit of Pediatric Hematology/Oncology, Department of Pediatrics, University of Catania, Catania, Italy.
Licciardello
Maria
M
Sorge
Giovanni
G
Cutrupi
Maria Concetta
MC
Di Benedetto
Fabrizio
F
Amoroso
Loredana
L
Catania
Roberta
R
Pennisi
Monica
M
D'Amico
Salvatore
S
Di Cataldo
Andrea
A
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000235:genetics; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D002648:Child; D019066:Facies; D005260:Female; D018197:Hepatoblastoma / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007223:Infant; D008607:Intellectual Disability / Q000175:diagnosis* / Q000235:genetics; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D011859:Radiography; D013577:Syndrome