title: [What contributes to the transformation of Helicobacter pylori from symbiont into the etiopathogenetical factor of duodenal ulcer?].
abstract: The aim was to study the relationship duodenogastral reflux (DGR) and Helicobacterpylori infection (Hp) at duodenal ulcer (DU).
  
  
  METHODS
  Group 1-50 patients with uncomplicated course of DU, Group 2-75 patients with destructive complications of DU; Group 3-40 "healthy" volunteers. It was performed daily EGDS, pH meter, semi-quantitative assessment of contamination of the Hp.
  
  
  RESULTS
  The acidity in the body of the stomach was highest in group 2, and lowest--in group 3, patients diagnosed DU night rush giperatsidnosti. In the night period patients from the 1st and 3rd groups were recorded an increase of antral pH, including the expense of growth duration of DGR, while in group 2 reflux was extremely short. The maximum Hp dissemination was in a bulb at fetomaternal of DU.
  
  
  CONCLUSIONS
  in healthy individuals DGR intragastral involved in the regulation of pH, in patients with uncomplicated DU while reducing the duration of this resonance persists compensation of antral alkalization, and complications throughout the DGR sharply depressed, which is accompanied by severe decompensation alkalization of antrum. Bulbs semination with Hp inversely proportional to the intensity of this resonance.
authors.forename: V S
authors.initials: VS
authors.lastname: Volkov
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Kolesnikova
authors.forename: V A
authors.initials: VA
authors.lastname: Leont'eva
authors.forename: A A
authors.initials: AA
authors.lastname: Smirnova
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000378:metabolism* / Q000382:microbiology; D004383:Duodenogastric Reflux / Q000378:metabolism* / Q000382:microbiology; D005260:Female; D005750:Gastric Juice / Q000378:metabolism / Q000382:microbiology; D016481:Helicobacter Infections / Q000378:metabolism* / Q000382:microbiology; D016480:Helicobacter pylori; D054884:Host-Pathogen Interactions; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D013559:Symbiosis