Synthesis and antifungal activities of new pyrazole derivatives via 1,3-dipolar cycloaddition reaction.
A series of cycloadducts--pyrazoles via 1,3-dipolar cycloaddition reactions of generated nitrilimines with N-(4-chloro-2-fluorophenyl)maleimide were described. The novel compounds synthesized were characterized by (1)H NMR, MS, and elemental analysis. The fungicidal tests showed that most of the title compounds exhibit significant fungicidal activities against Corynespora cassiicola.
Zhang
Chuan-Yu
CY
Nankai University, Tianjin, China.
Liu
Xing-Hai
XH
Wang
Bao-Lei
BL
Wang
Su-Hua
SH
Li
Zheng-Ming
ZM
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018360:Crystallography, X-Ray; D003500:Cyclization; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D011720:Pyrazoles