Pulmonary tuberculosis due to Mycobacterium microti: a study of six recent cases in France.
Human tuberculosis caused by Mycobacterium microti is rare, but its prevalence and clinical significance may have been underestimated. To the best of our knowledge, 21 cases have been reported in the literature in the last decade. We report six recent pulmonary cases caused by M. microti over a period of 5 years detected in French clinical mycobacteriology laboratories of the hospital network. Our data confirm the potential of M. microti to cause clinical illness in immunocompetent patients. M. microti grew slowly from specimens, delaying the final microbiological diagnosis. Therefore, patients with tuberculosis caused by M. microti could benefit from the use of rapid diagnostic molecular techniques directly on clinical samples. From a review of the literature and this study, a classical antituberculous therapy seems effective in treating patients with M. microti disease.
Panteix
G
G
Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
Gutierrez
M C
MC
Institut Pasteur de Lille, INSERM U629, 1 Rue du Professeur Calmette, 59021 Lille, France.
Boschiroli
M L
ML
Unité Zoonoses Bactériennes, Agence Française de Sécurité Sanitaire des Aliments, 23 Avenue du Général de Gaulle, 94706 Maisons-Alfort Cedex, France.
Rouviere
M
M
Laboratoire de Biologie, Centre Hospitalier Général Gui de Chauliac de Mende, Avenue du 8 Mai 1945, BP 10, 48010 Mende Cedex, France.
Plaidy
A
A
Laboratoire de Biologie, Centre Hospitalier de Vichy, Boulevard Deniere, BP 2757, 03207 Vichy Cedex, France.
Pressac
D
D
Laboratoire de Biologie, Centre Hospitalier de Tulle, 3 Place Maschat, BP 160, 19012 Tulle Cedex, France.
Porcheret
H
H
Laboratoire de Biologie, Centre Hospitalier Robert Ballanger (CHRB), 93602 Aulnay-Sous-Bois Cedex, France.
Chyderiotis
G
G
Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
Ponsada
M
M
Laboratoire Biomnis, 19 Avenue Tony Garnier, 69007 Lyon, France.
Van Oortegem
K
K
Service de Pneumologie, Centre Hospitalier Général Gui de Chauliac de Mende, Avenue du 8 Mai 1945, BP 10, 48010 Mende Cedex, France.
Salloum
S
S
Service de Pneumologie, Centre Hospitalier de Vendome, 41106 Vendome Cedex, France.
Cabuzel
S
S
Service de Médecine Interne et Pneumologie, Centre Hospitalier d'Aubenas, 9 Chemin de Bois Vignal, BP 146, 07205 Aubenas, France.
Bañuls
A L
AL
GEMI, UMR CNRS-IRD 2724, Centre IRD de Montpellier, France.
Van de Perre
P
P
Université Montpellier 1, EA 4205 'Transmission, Pathogenèse et Prévention de l'Infection par le VIH', and Laboratoire de Bactériologie-Virologie Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, F-34295 Montpellier Cedex 5, France.
Godreuil
S
S
Université Montpellier 1, EA 4205 'Transmission, Pathogenèse et Prévention de l'Infection par le VIH', and Laboratoire de Bactériologie-Virologie Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, F-34295 Montpellier Cedex 5, France.|GEMI, UMR CNRS-IRD 2724, Centre IRD de Montpellier, France.
D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*
D000995:Antitubercular Agents