title: Developmental profile of three enolase isozymes in rat brain determination from one-cell embryo to adult brain.
abstract: Levels of three enolase isozymes (??, ?? and ??) were determined in rat tissues from one-cell embryo to adult brain with a sensitive enzyme immunoassay system. Each embryo of the early stage (gestational age, 0-3 days) contained about 5 x 10(?17) mol of ?? enolase. The nervous system-specific ?? and ?? enolases would be detected in the embryos of 6-8 days, which contain no histologically recognizable neurones. The 8-day embryos contained 4.3 x 10(?17) and 3.4 x 10(?16) mol of ?? and ?? enolases. Amounts of all the three enolases were increased with growth of the embryo. The nervous system-specific enolases (?? and ??) in the brain kept increasing until 1-2 months of postnatal age, whereas the ?? enolase level in the brain was relatively constant after the 15-day embryo through the adult rat.
authors.affiliation: Department of Biochemistry, Institute for Developmental Research, Aichi Prefectural Colony, Kasugai, Aichi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: F
authors.initials: F
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: R
authors.initials: R
authors.lastname: Semba
authors.forename: H
authors.initials: H
authors.lastname: Keino