title: Emergent and unusual allergens in cosmetics.
abstract: Allergic contact dermatitis from cosmetics is a common problem that is occasionally caused by new or rare allergens. When a patient has a positive patch test to a cosmetic product but to none of the common or commercially available allergens, it is important to further patch-test this patient to the ingredients of the product. Thorough testing with the breakdown of ingredients, usually obtained through cooperation with the manufacturer, often allows identification of the culprit allergen in the cosmetic product. In this article, we discuss emerging or rare allergens discovered by this method, including nail lacquer and lipstick allergens, copolymers, shellac, alkyl glucosides, glycols, protein derivatives, idebenone, and octocrylene.
authors.affiliation: Department of Dermatology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
authors.forename: David
authors.initials: D
authors.lastname: Pascoe
authors.forename: Linda
authors.initials: L
authors.lastname: Moreau
authors.forename: Denis
authors.initials: D
authors.lastname: Sasseville
mesh_terms: D000179:Acrylates / Q000009:adverse effects; D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000009:adverse effects*; D002368:Castor Oil / Q000009:adverse effects; D003358:Cosmetics / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005227:Fatty Acids / Q000009:adverse effects; D005260:Female; D005960:Glucosides / Q000009:adverse effects; D006018:Glycols / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D011409:Propylene Glycols / Q000009:adverse effects; D012116:Resins, Plant / Q000009:adverse effects; D014451:Ubiquinone / Q000009:adverse effects / Q000031:analogs & derivatives; D055815:Young Adult
chemical_list: D000179:Acrylates; D000485:Allergens; D003358:Cosmetics; D005227:Fatty Acids; D005960:Glucosides; D006018:Glycols; D011409:Propylene Glycols; D012116:Resins, Plant; D014451:Ubiquinone; C003934:shellac; C088673:octocrylene; D002368:Castor Oil; C036619:idebenone; C487451:pentaerythritol rosinate