title: Morphological peculiarities of endometrium in chronic endometritis associated with bacterial vaginosis.
abstract: Most cervical cancers begin where the endocervix and ectocervix meet. Pap tests (also called Pap smears) are vital in the early detection of cervical cancer. Ecto-endocervical Pap-tests from 230 patients with verified bacterial vaginosis (BV) were studied. Endometrial biopsy was also used in the evaluation of 95 patients (47 with primary diagnosis BV and 48 relapsing BV). Control specimens were obtained from physically and gynecologically healthy females'. Biopsy samples were collected from endometrium of the uterine body. Morphological and morphometrical analysis of data and Pap-test criteria indicate that chronic endometritis (100%) as well as spontaneous abortion syndrome (20-25%) can be reasonably considered as primary and relapsing bacterial vaginosis (BV) associated pathologic processes. The chief morphological phenomena of chronic endometritis involve the severe dystrophic - atrophic alterations in lining and glandular epithelium, simultaneously with the polymorphic cellular infiltration and stromal transformation of the different intensity. Progressive atrophy of epithelium and fibroplastic transformation of stroma evidently contributes to the evolution of the condition preventing the implantation and development of the conceptus.
authors.affiliation: A. Natishvili Institute of Morphology.
authors.forename: M
authors.initials: M
authors.lastname: Beruchashvili
authors.forename: L
authors.initials: L
authors.lastname: Gogiashvili
authors.forename: E
authors.initials: E
authors.lastname: Datunashvili
authors.forename: Z
authors.initials: Z
authors.lastname: Topuria
authors.forename: Z
authors.initials: Z
authors.lastname: Tsagareli
mesh_terms: D001284:Atrophy; D002908:Chronic Disease; D004716:Endometritis / Q000209:etiology / Q000378:metabolism*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D016585:Vaginosis, Bacterial / Q000150:complications*