title: [Orbital lymphoma].
abstract: BACKGROUND
  Orbital lymphomas are neoplasms with increasing incidence in recent years in immunocompromised, as well as immunocompetent patients, which defines their social importance.
  
  
  OBJECTIVE
  To describe and analyze the experience of the University hospital "'Sv. Ivan Rilski" with the treatment of this pathology for the period 1997-2008.
  
  
  METHODS
  Fourteen patients (8 females, 6 males - 13 primary orbital lymphomas, 1 systemic lymphoma). Mean age at diagnosis was 65.6 years (from 50 to 80 years). In 2/3 of the patients the lesion was localized in left eye, without a case with bilateral orbital involvement. Seven cases the diagnosis was made 6 months from the onset of symptoms, 5 cases - 1 year and 2 cases - more than one year. The most common clinical symptoms were exophthalmus (12 case), tumor or bulging mass of the eyelid - 8, diplopy - 6, decreased visual acuity - 5. Intraconal localization of the tumor was in 6 cases, extraconal - 2. intra-extraconal - 6. The diagnosis was made by neuro-ophthalmologist and precised with the aid of CT and MRI. All the patients were operated on with the following approaches - fronto-orbital - 9 cases, lateral - 3, anterior orbitotomy (without bone resection) - 2 cases. In six cases "'gross total" resection was achieved, in the rest of the cases the resection was partial. On histological examination, a high grade lymphoma was established in 2 cases with primary orbital lymphoma and one case with systemic lymphoma. All other cases were diagnosed as low-grade B-call small lymphocytic non-Hodgkin's lymphoma. Long-term survival (over 5 years) was observed in 4 cases with primary lymphoma, whereas the patient with systemic form of the disease died 10 months after the operation.
authors.forename: Ch
authors.initials: Ch
authors.lastname: Tzekov
authors.forename: T
authors.initials: T
authors.lastname: Spiriev
authors.forename: S
authors.initials: S
authors.lastname: Hristova
authors.forename: S
authors.initials: S
authors.lastname: Chernikova
authors.forename: K
authors.initials: K
authors.lastname: Minkin
authors.forename: E
authors.initials: E
authors.lastname: Naydenov
authors.forename: V
authors.initials: V
authors.lastname: Bussarsky
authors.forename: K
authors.initials: K
authors.lastname: Romansky
authors.forename: M
authors.initials: M
authors.lastname: Marinov
authors.forename: O
authors.initials: O
authors.lastname: Kalev
authors.forename: A
authors.initials: A
authors.lastname: Cekov
authors.forename: L
authors.initials: L
authors.lastname: Laleva
authors.forename: D
authors.initials: D
authors.lastname: Kolarov
authors.forename: R
authors.initials: R
authors.lastname: Tanova
authors.forename: V
authors.initials: V
authors.lastname: Enchev
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000473:pathology* / Q000601:surgery*; D016393:Lymphoma, B-Cell / Q000473:pathology / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D009918:Orbital Neoplasms / Q000473:pathology* / Q000601:surgery*; D016019:Survival Analysis