title: Cyclodextrins: more than pharmaceutical excipients.
abstract: Cyclodextrins are pharmaceutical excipients used to enhance the solubility, stability, safety and bioavailability of drugs. Recent findings have shown them to display adjuvant activity in vaccine therapy and prophylactic and therapeutic activity in the treatment of several host-pathogen infections. This article focuses on their activity and mechanism of action.
authors.affiliation: Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Campus Universitario sur s/n. 15782 Santiago de Compostela, Spain. francisco.otero@usc.es
authors.forename: F J
authors.initials: FJ
authors.lastname: Otero-Espinar
authors.forename: A
authors.initials: A
authors.lastname: Luzardo-Alvarez
authors.forename: J
authors.initials: J
authors.lastname: Blanco-Méndez
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000977:Antiparasitic Agents / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology; D003505:Cyclodextrins / Q000737:chemistry* / Q000494:pharmacology; D005079:Excipients / Q000737:chemistry* / Q000494:pharmacology; D007155:Immunologic Factors / Q000737:chemistry / Q000494:pharmacology; D017510:Protein Folding
chemical_list: D000900:Anti-Bacterial Agents; D000977:Antiparasitic Agents; D000998:Antiviral Agents; D003505:Cyclodextrins; D005079:Excipients; D007155:Immunologic Factors