[Role of Toll-like receptors in the therapeutic effect of probiotics].
We considered data on the interaction of probiotics with Toll-like receptors. Is was shown that the probiotic effect may have and intact bacterial cells, living or dead, and their structural components. The basis of the surface structures and the DNA of probiotics is the ability to interact with Toll-like receptors, and this interaction can lead to uneven effects, which greatly depends on the strain of probiotic. Hence the obvious need for a more detailed study of the effects of the interaction of probiotic strains with the Toll-receptors. The criteria for evaluating new drugs probiotioticheskih and feasibility of optimal probiotic in a particular clinical case.
Bondarenko
V M
VM
Likhoded
V G
VG
D000818:Animals; D001419:Bacteria / Q000276:immunology*; D004269:DNA, Bacterial / Q000276:immunology*; D006801:Humans; D019936:Probiotics / Q000494:pharmacology*; D051193:Toll-Like Receptors / Q000276:immunology*
D004269:DNA, Bacterial; D051193:Toll-Like Receptors