title: Phosphine-free chiral metal catalysts for highly effective asymmetric catalytic hydrogenation.
abstract: In addition to the brilliant chiral phosphorus metal catalysts, chiral phosphine-free metal complexes find increasing application as catalysts for asymmetric hydrogenation. In this account, two types of chiral phosphine-free ligands, N-heterocyclic carbene-based C,N-ligands and diamine-based N,N-ligands, in the homogeneous asymmetric hydrogenation of prochiral ketones, imines and quinolines are reviewed.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Yan-Mei
authors.initials: YM
authors.lastname: He
authors.forename: Qing-Hua
authors.initials: QH
authors.lastname: Fan
mesh_terms: D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry; D011804:Quinolines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D056831:Coordination Complexes; D006571:Heterocyclic Compounds; D007097:Imines; D007659:Ketones; D010720:Phosphines; D011804:Quinolines; C030011:carbene; C044646:phosphine; D008697:Methane