No effect of arm-crank exercise on diaphragmatic fatigue or ventilatory constraint in Paralympic athletes with cervical spinal cord injury.
Cervical spinal cord injury (CSCI) results in a decrease in the capacity of the lungs and chest wall for pressure, volume, and airflow generation. We asked whether such impairments might increase the potential for exercise-induced diaphragmatic fatigue and mechanical ventilatory constraint in this population. Seven Paralympic wheelchair rugby players (mean + or - SD peak oxygen uptake = 16.9 + or - 4.9 ml x kg(-1) x min(-1)) with traumatic CSCI (C(5)-C(7)) performed arm-crank exercise to the limit of tolerance at 90% of their predetermined peak work rate. Diaphragm function was assessed before and 15 and 30 min after exercise by measuring the twitch transdiaphragmatic pressure (P(di,tw)) response to bilateral anterolateral magnetic stimulation of the phrenic nerves. Ventilatory constraint was assessed by measuring the tidal flow volume responses to exercise in relation to the maximal flow volume envelope. P(di,tw) was not different from baseline at any time after exercise (unpotentiated P(di,tw) = 19.3 + or - 5.6 cmH(2)O at baseline, 19.8 + or - 5.0 cmH(2)O at 15 min after exercise, and 19.4 + or - 5.7 cmH(2)O at 30 min after exercise; P = 0.16). During exercise, there was a sudden, sustained rise in operating lung volumes and an eightfold increase in the work of breathing. However, only two subjects showed expiratory flow limitation, and there was substantial capacity to increase both flow and volume (<50% of maximal breathing reserve). In conclusion, highly trained athletes with CSCI do not develop exercise-induced diaphragmatic fatigue and rarely reach mechanical ventilatory constraint.
Taylor
Bryan J
BJ
Centre for Sports Medicine and Human Performance, Brunel Univ., Uxbridge UB8 3PH, UK.
West
Christopher R
CR
Romer
Lee M
LM
D000328:Adult; D001132:Arm; D002574:Cervical Vertebrae / Q000293:injuries*; D003964:Diaphragm / Q000294:innervation / Q000503:physiopathology*; D006233:Persons with Disabilities; D004558:Electric Stimulation; D005260:Female; D005538:Football; D006801:Humans; D008280:Magnetics; D008297:Male; D009119:Muscle Contraction; D018763:Muscle Fatigue; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000503:physiopathology*; D010101:Oxygen Consumption; D010264:Paraplegia / Q000503:physiopathology*; D010791:Phrenic Nerve / Q000503:physiopathology; D010807:Physical Endurance; D012123:Pulmonary Ventilation; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D013997:Time Factors; D014910:Wheelchairs