title: Evaluation of anterior lenticonus in alport syndrome using tracey wavefront aberrometry and transmission electron microscopy.
abstract: OBJECTIVE
  To evaluate the efficacy of Tracey wavefront aberrometry (Tracey Technologies, Houston, TX) and transmission electron microscopy for the detection of anterior lenticonus in Alport syndrome.
  
  
  METHODS
  Tracey wavefront aberrometry was used to treat a patient with bilateral anterior lenticonus who had a history of Alport syndrome. For transmission electron microscopic examination, anterior lens capsules were obtained during clear lens phacoemulsification and intraocular lens implantation.
  
  
  RESULTS
  Spherical aberrations were the predominant higher-order aberrations in the internal optics of both eyes. The Tracey wavefront aberrometer showed that most of the irregular astigmatism originated from the lenticular portion. Transmission electron microscopy of the specimens showed anterior lens capsules with decreased thickness and multiple dehiscences.
  
  
  CONCLUSIONS
  Tracey wavefront aberrometry and transmission electron microscopy are effective tools for evaluation of anterior lenticonus in Alport syndrome.
authors.affiliation: Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Kim
authors.forename: Mo Sae
authors.initials: MS
authors.lastname: Kim
authors.forename: Joon Mo
authors.initials: JM
authors.lastname: Kim
authors.forename: Chul Young
authors.initials: CY
authors.lastname: Choi
mesh_terms: D057128:Aberrometry / Q000379:methods*; D000328:Adult; D003315:Cornea / Q000473:pathology; D019781:Corneal Topography; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007905:Lens Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000648:ultrastructure*; D008297:Male; D046529:Microscopy, Electron, Transmission / Q000379:methods*; D009394:Nephritis, Hereditary / Q000150:complications* / Q000175:diagnosis; D018918:Phacoemulsification / Q000379:methods; D012029:Refraction, Ocular; D015203:Reproducibility of Results; D016896:Treatment Outcome; D014792:Visual Acuity