title: Usefulness of autofluorescence imaging for estimating the extent of gastric neoplastic lesions: a prospective multicenter study.
abstract: OBJECTIVE
  The aim of this study was to determine whether the margin of early to be detected gastric cancer (EGC) and gastric adenoma is easier to be detected with autofluorescence imaging (AFI) than with white-light endoscopy (WLE).
  
  
  METHODS
  A total of 102 lesions (48 EGCs and 54 gastric adenomas) found in 98 patients were removed endoscopically or surgically. The measured length of each pathology specimen was compared with the lengths estimated using WLE, AFI, and chromoendoscopy.
  
  
  RESULTS
  The lesions could be discriminated from surrounding mucosa by AFI in 86 cases (84.3%). The detection rates were similar for elevated lesions (85.1%) and flat/depressed lesions (82.9%, p=0.770). In terms of histology, the detection rate was slightly higher for adenomas (90.7%) than for cancer (77.1%, p=0.058). The estimated length was shorter than the pathologic length in 31.4% of cases when using WLE and 22.1% of cases when using AFI (p=0.168). The resection range was larger for EMR than for AFI in 24 of 80 cases (30.0%).
  
  
  CONCLUSIONS
  WLE tends to underestimate the size of EGCs, whereas AFI tends to overestimate their size.
authors.affiliation: Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
authors.forename: Jun Haeng
authors.initials: JH
authors.lastname: Lee
authors.forename: Joo Yong
authors.initials: JY
authors.lastname: Cho
authors.forename: Myung Gyu
authors.initials: MG
authors.lastname: Choi
authors.forename: Joo Sung
authors.initials: JS
authors.lastname: Kim
authors.forename: Kee Don
authors.initials: KD
authors.lastname: Choi
authors.forename: Yong Chan
authors.initials: YC
authors.lastname: Lee
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Jang
authors.forename: Hoon Jai
authors.initials: HJ
authors.lastname: Chun
authors.forename: Sang Yong
authors.initials: SY
authors.lastname: Seol