Liberation and animation for ventilated ICU patients: the ABCDE bundle for the back-end of critical care.
Critically ill patients are frequently prescribed sedatives and analgesics to ensure patient safety, to relieve pain and anxiety, to reduce stress and oxygen consumption, and to prevent patient ventilator dysynchrony. Recent studies have revealed that these medications themselves contribute to worsening clinical outcomes. An evidence-based organizational approach referred to as the ABCDE bundle (Awakening and Breathing Coordination of daily sedation and ventilator removal trials; Choice of sedative or analgesic exposure; Delirium monitoring and management; and Early mobility and Exercise) is presented in this commentary.
Pandharipande
Pratik
P
Anesthesiology Service, VA TN Valley Health Care System, 1310 24th Ave South, Nashville 37212, USA. pratik.pandharipande@vanderbilt.edu
Banerjee
Arna
A
McGrane
Stuart
S
Ely
E Wesley
EW
D000075202:Contraindications; D003422:Critical Care / Q000379:methods*; D055317:Evidence-Based Practice; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects / Q000627:therapeutic use*; D007362:Intensive Care Units; D017146:Models, Organizational; D012121:Respiration, Artificial
D006993:Hypnotics and Sedatives