title: [Assessment of global left and right ventricular function with 64 multi-detector row computed tomography in healthy adults].
abstract: To evaluate the global left and right ventricular function and establish the CT reference data of global ventricular function parameters in normal people, 56 normal subjects (male, 28 cases; female, 28 case) were scanned with retrospective ECG gated 64-detector row CT. Ten time-phases in the cardiac cycle were reconstructed and short-axis images were acquired. On the cardiac analysis software, endo-cardium and epi-cardium of left and right ventricle were delineated and global function parameters were calculated. Left and right ventricular end-diastolic volume (LV/RVEDV), end-systolic volume (LV/RVESV), stroke volume (LV/RVSV), and wall mass (LV/RVWM) were significantly greater (P < 0.05) in men than in women, but cardiac output (LV/RVCO) and ejection fraction (LV/RVEF) exhibited no difference in women and men. In man group and woman group, LVWM was greater than RVWM (P < 0.01). LVESV, RVESV and body mass Index (BMI) were shown to have significant negative-correlation; the correlation coefficient = -0.54 and r = -0.53. LV/RVSV, LV/RVEF and BMI were noted to have significant positive-correlation; the correlation coefficients were 0.87/0.97 and 0.69/0.62, respectively. The normal global left and right ventricular functions differ significantly according to gender and body size.
authors.affiliation: Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Yang
authors.forename: Yingkun
authors.initials: Y
authors.lastname: Guo
authors.forename: Qiling
authors.initials: Q
authors.lastname: Wang
authors.forename: Tianwu
authors.initials: T
authors.lastname: Chen
authors.forename: Ensen
authors.initials: E
authors.lastname: Ma
mesh_terms: D000328:Adult; D000368:Aged; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012189:Retrospective Studies; D013318:Stroke Volume; D036542:Tomography, Spiral Computed / Q000379:methods*; D016277:Ventricular Function, Left / Q000502:physiology*; D016278:Ventricular Function, Right / Q000502:physiology*