Comparative outcomes between hemo- and peritoneal dialysis patients with acute intracerebral hemorrhage.
OBJECTIVE
The optimal mode of dialysis for end-stage renal disease (ESRD) patients with spontaneous intracerebral hemorrhage (ICH) remains controversial. We compared the outcomes of ESRD patients who received continuous peritoneal dialysis (CPD) or extended hemodialysis (EHD) after ICH, and investigated the factors determining prognosis.


METHODS
We incorporated our ICH patients with ESRD, requiring dialysis from January 2005 to December 2009. Patients were allocated to the CPD or EHD group according to the dialysis mode after ICH. We compared the 30-day mortality rate and modified Rankin Scale (mRS) of the two groups and analyzed the factors associated with mortality.


RESULTS
There were 40 patients with 16 episodes in CPD and 27 episodes in EHD group, without significant differences in baseline demographic data. The 30-day mortality rate and mRS were not different between the two groups. The patients who died within 30 days had higher ICH scores (4 +/- 1 vs. 1 +/- 1, p < 0.001) and outcome scores (5 +/- 2 vs. 1 +/- 1, p < 0.001). Dialysis-related complications occurred more frequently in the PD group (p = 0.07), but were unrelated to mortality.


CONCLUSIONS
Among ESRD patients with ICH, EHD had a similar 30-day mortality rate and 30-day mRS to those receiving CPD. The mortality was significantly related to the severity of ICH.
Hsieh
Cheng-Yang
CY
Stroke Center, National Cheng Kung University Hospital, Tainan, Taiwan.
Chen
Chih-Hung
CH
Wu
An-Bang
AB
Tseng
Chin-Chung
CC
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000401:mortality* / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000401:mortality* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000401:mortality*; D015995:Prevalence; D011379:Prognosis; D006435:Renal Dialysis / Q000401:mortality*; D012720:Severity of Illness Index; D016896:Treatment Outcome