title: [Helicobacter pylori resistance].
abstract: Helicobacter pylori (H. pylori) is recognized as the causative of several gastroduodenal disorders. The discovery of H. pylori revolutionized the treatment for ulcus pepticum. Antibiotics combined with proton pump inhibitors or bismuth have been effective in the treatment of H. pylori infections, but there is an emerging problem with H. pylori resistance against the most frequently used antibiotics, which substantially impairs the treatment of H. pylori-associated disorders. In this article the focus is on the prevalence of H. pylori resistance, its clinical implications and the molecular mechanisms behind resistance development.
authors.affiliation: Neurokirugisk Afdeling, Glostrup Hospital, 2600 Glostrup, Denmark. Dalaho112@hotmail.com
authors.forename: Jalal
authors.initials: J
authors.lastname: Alimoradi
authors.forename: Lone
authors.initials: L
authors.lastname: Rasmussen
authors.forename: Leif Percival
authors.initials: LP
authors.lastname: Andersen
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics / Q000502:physiology; D014943:Global Health; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D015994:Incidence; D015995:Prevalence; D013276:Stomach Ulcer / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents