Value of sonohysterography in preoperative assessment of myometrial invasion for patients with endometrial cancer.
OBJECTIVE
The aims of this study were to compare the diagnostic performance of sonohysterography (SH) with that of magnetic resonance imaging (MRI) in estimation of myometrial invasion and to evaluate the influence of SH on peritoneal cytologic results for patients with endometrial cancer.


METHODS
Seventy-four patients with endometrial cancer were included. Sonohysterography and MRI were performed before surgery. All patients had complete staging procedures, including peritoneal cytologic analyses. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were determined for SH and MRI.


RESULTS
The concordance rates of myometrial invasion for SH and MRI were 82.4% and 81.1%, respectively. The sensitivity, specificity, PPV, and NPV for identification of deep myometrial invasion were 64.7%, 87.7%, 61.1%, and 89.3% on SH and 70.6%, 84.2%, 57.1%, and 90.6% on MRI. Two patients (2.7%) were found to have positive results for malignant cells on peritoneal cytologic analyses.


CONCLUSIONS
Sonohysterography appears to be a useful preoperative method for predicting myometrial invasion, comparable to MRI.
Chang
Suk-Joon
SJ
Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.
Lee
Eun Ju
EJ
Kim
Woo Young
WY
Yoo
Seung-Chul
SC
Yoon
Jong-Hyuck
JH
Chang
Ki-Hong
KH
Ryu
Hee-Sug
HS
D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003287:Contrast Media; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D016015:Logistic Models; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009215:Myometrium / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011300:Preoperative Care; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014621:Vagina
D003287:Contrast Media; D019786:Gadolinium DTPA