title: Systematic reviews of the effectiveness and cost-effectiveness of multi-channel unilateral cochlear implants for adults.
abstract: OBJECTIVE
  In the UK approximately 3% of over 50 years olds and 8% of over 70 year olds have severe (794-94 dBHL) to deafness. As deafness increased, hearing aids become increasingly ineffective. Cochelear implants can provide an alternative treatment.
  
  
  OBJECTIVE
  To bring together the research evidence through the robustness of a systematic review of the effectiveness of unilateral cochlear implants for adults. We also sought to systematically review the published literature on cost-effectiveness. TYPES OF REVIEW: Systematic review.
  
  
  METHODS
  This examined 16 electronic databases, plus bibliographies and references for published and unpublished studies from inception to june 2009.
  
  
  METHODS
  Abstracts were independently assessed against inclusion criteria by two researchers were compared and disagreements resolved. Included papers were then retrieved and further independently assessed in a similar way. Remaining studies had their data independently extracted by one of five reviewers and checked by another reviewer.
  
  
  RESULTS
  From 1,580 titles and abstracts nine studies were included. These were of variable quality; some study's results should be viewed with caution. The studies were too hetrogeneous to pool the data. However, overall the results firmly supported the use of unilateral cochler implants for severe to profoundly deaf adults. Additionally, four UK based economic evaluations found unilateral cochlear implants to be cost-effectivene in adults at UK implants centres.
  
  
  CONCLUSIONS
  The methodologically weak but universally positive body of effectiveness evidence supports the use of unilateral cochlear implants in adults. Previous economic evaluations indicate that such implants are likely to be cost-effective.
authors.affiliation: Peninsula Medical School, University of Exeter, Exeter, EX2 4SG, UK. mary.bond@pms.ac.uk
authors.forename: M
authors.initials: M
authors.lastname: Bond
authors.forename: J
authors.initials: J
authors.lastname: Elston
authors.forename: S
authors.initials: S
authors.lastname: Mealing
authors.forename: R
authors.initials: R
authors.lastname: Anderson
authors.forename: G
authors.initials: G
authors.lastname: Weiner
authors.forename: R
authors.initials: R
authors.lastname: Taylor
authors.forename: K
authors.initials: K
authors.lastname: Stein
mesh_terms: D000328:Adult; D019929:Cochlear Implantation / Q000191:economics / Q000295:instrumentation; D003054:Cochlear Implants / Q000191:economics*; D003362:Cost-Benefit Analysis; D003638:Deafness / Q000601:surgery; D046088:Hearing Loss, Unilateral / Q000191:economics* / Q000601:surgery*; D006801:Humans; D011474:Prosthesis Design; D016896:Treatment Outcome