title: Periodontal therapy and risk for adverse pregnancy outcomes.
abstract: Periodontitis has been associated with adverse pregnancy outcomes. Results from intervention studies are few and controversial. The present study assessed the effects of non-surgical periodontal treatment in the occurrence of adverse pregnancy outcomes. Two hundred forty-six eligible women were randomly divided into two groups: periodontitis intervention (n = 122; undergoing non-surgical treatment during gestation) and periodontitis control (n = 124; not treated during gestation). Univariate analysis was performed and estimates of relative risk were reported. Data from 225 women were analyzed. No differences for preterm birth (p = 0.721), low birth weight (p = 0.198), and preterm low birth weight (p = 0.732) rates were observed. Relative risk estimates for preterm birth, low birth weight, and preterm low birth weight in the periodontitis intervention group were 0.915 (95% CI 0.561-1.493), 0.735 (95% CI 0.459-1.179), and 0.927 (0.601-1.431), respectively. Non-surgical periodontal treatment during the second semester of gestation did not reduce the risk for preterm birth, low birth weight, and preterm low birth weight.
authors.affiliation: Department of Periodontology, Pontific Catholic University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Alcione Maria Soares Dutra
authors.initials: AM
authors.lastname: Oliveira
authors.forename: Peterson Antonio Dutra
authors.initials: PA
authors.lastname: de Oliveira
authors.forename: Luís Otávio Miranda
authors.initials: LO
authors.lastname: Cota
authors.forename: Claúdia Silami
authors.initials: CS
authors.lastname: Magalhães
authors.forename: Allyson Nogueira
authors.initials: AN
authors.lastname: Moreira
authors.forename: Fernando Oliveira
authors.initials: FO
authors.lastname: Costa
mesh_terms: D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D003774:Dental Plaque Index; D003777:Dental Prophylaxis; D005260:Female; D005884:Gingival Hemorrhage / Q000628:therapy; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D009910:Oral Hygiene / Q000193:education; D010353:Patient Education as Topic; D017622:Periodontal Attachment Loss / Q000628:therapy; D057747:Periodontal Debridement; D010514:Periodontal Pocket / Q000628:therapy; D010518:Periodontitis / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D047928:Premature Birth / Q000209:etiology; D018570:Risk Assessment; D047929:Term Birth; D055815:Young Adult