title: Mother's occupation and sex ratio at birth.
abstract: BACKGROUND
  Many women are working outside of the home, occupying a multitude of jobs with varying degrees of responsibilities and levels of psychological stress. We investigated whether different job types in women are associated with child sex at birth, with the hypothesis that women in job types, which are categorized as "high psychological stress" jobs, would be more likely to give birth to a daughter than a son, as females are less vulnerable to unfavourable conditions during conception, pregnancy and after parturition, and are less costly to carry to term.
  
  
  METHODS
  We investigated the effects of mother's age, maternal and paternal job type (and associated psychological stress levels) and paternal income on sex ratio at birth. Our analyses were based on 16,384 incidences of birth from a six-year (2000 to 2005 inclusive) childbirth dataset from Addenbrooke's Hospital in Cambridge, UK. We obtained a restricted data set from Addenbrooke's hospital with: maternal age, maternal and paternal occupations, and whether or not the child was first-born.
  
  
  RESULTS
  Women in job types that were categorized as "high stress" were more likely to give birth to daughters, whereas women in job types that were categorized as "low stress" had equal sex ratios or a slight male bias in offspring. We also investigated whether maternal age, and her partner's income could be associated with reversed offspring sex ratio. We found no association between mother's age, her partner's job stress category or partner income on child sex. However, there was an important interaction between job stress category and partner income in some of the analyses. Partner income appears to attenuate the association between maternal job stress and sex ratios at moderate-income levels, and reverse it at high-income levels.
  
  
  CONCLUSIONS
  To our knowledge this is the first report on the association between women's job type stress categories and offspring sex ratio in humans, and the potential mitigating effect of their partners' income.
authors.affiliation: University of Calgary, Department of Biological Sciences, 2500 University Drive NW, Calgary, Alberta, T2N 1N4, Canada. kruckstu@ucalgary.ca
authors.forename: Kathreen E
authors.initials: KE
authors.lastname: Ruckstuhl
authors.forename: Grant P
authors.initials: GP
authors.lastname: Colijn
authors.forename: Volodymyr
authors.initials: V
authors.lastname: Amiot
authors.forename: Erin
authors.initials: E
authors.lastname: Vinish
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006761:Hospitals / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009790:Occupations / Q000145:classification*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology*; D012744:Sex Ratio; D013315:Stress, Psychological; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult