title: Migraine and olfactory stimuli.
abstract: Migraine patients often report intolerance to odours. Migraineurs report odours may trigger attacks, that they experience osmophobia during attacks, and olfactory hypersensitivity between attacks. In this paper we discuss olfactory mechanisms in migraine. We also present data from a pilot questionnaire study in a group of young women diagnosed with migraine. The study results confirm that hypersensitivity to odour is a common feature in women with migraine. Migraine pathophysiology likely explains this particular vulnerability. We discuss these pathophysiologic mechanisms and hypotheses relating odour intolerances and migraine.
authors.affiliation: Headache Research Centre, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. christina.sjostrand@ki.se
authors.forename: Christina
authors.initials: C
authors.lastname: Sjöstrand
authors.forename: Ivanka
authors.initials: I
authors.lastname: Savic
authors.forename: Eva
authors.initials: E
authors.lastname: Laudon-Meyer
authors.forename: Lena
authors.initials: L
authors.lastname: Hillert
authors.forename: Karin
authors.initials: K
authors.lastname: Lodin
authors.forename: Elisabet
authors.initials: E
authors.lastname: Waldenlind
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000150:complications / Q000503:physiopathology*; D009812:Odorants; D000857:Olfaction Disorders / Q000209:etiology / Q000503:physiopathology*; D055696:Olfactory Perception / Q000502:physiology; D010865:Pilot Projects; D012903:Smell / Q000502:physiology; D011795:Surveys and Questionnaires; D055815:Young Adult