Recent advances in rapid and ultrasensitive biosensors for infectious agents: lesson from Bacillus anthracis diagnostic sensors.
Here, we review the cumulative efforts to develop rapid and ultrasensitive diagnostic systems, especially for the infectious agent, Bacillus anthracis, as a model system. This Minireview focuses on demonstrating the features of various probes for target molecule detection and recent methods of signal generation within the biosensors. Also, we discuss the possibility of using peptides as next-generation probe molecules.
Kim
Joungmok
J
Department of Chemistry, Research Institute for Natural Sciences, Hanyang University, Seoul 133-791, Korea.
Yoon
Moon-Young
MY
D000881:Anthrax / Q000175:diagnosis*; D001408:Bacillus anthracis / Q000302:isolation & purification*; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D007118:Immunoassay / Q000379:methods; D008163:Luminescent Measurements / Q000379:methods; D021141:Nucleic Acid Amplification Techniques / Q000379:methods; D010455:Peptides / Q000737:chemistry / Q000378:metabolism
D010455:Peptides; D004247:DNA