title: Identification of X chromosome copies by quantitative real-time polymerase chain reaction for population screening tests.
abstract: We adapted a method that allows the identification of X chromosome copy number by quantitative real-time polymerase chain reaction (PCR) in a short amount of time. It may be used for sex and aneuploidy involving X chromosome large population screening tests.
authors.affiliation: Department of Genetics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. esramos@rge.fmrp.usp.br
authors.forename: Ester S
authors.initials: ES
authors.lastname: Ramos
authors.forename: Juliana V
authors.initials: JV
authors.lastname: Serafim
authors.forename: Paula L
authors.initials: PL
authors.lastname: Takeuchi
authors.forename: Cintia R
authors.initials: CR
authors.lastname: Marcondes
authors.forename: Adriane
authors.initials: A
authors.lastname: Araújo
mesh_terms: D000782:Aneuploidy; D016022:Case-Control Studies; D058674:Chromosome Duplication; D041321:Chromosomes, Human, X / Q000235:genetics; D005260:Female; D018628:Gene Dosage; D005820:Genetic Testing / Q000379:methods*; D005828:Genetics, Population / Q000379:methods; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*; D012729:Sex Chromosome Aberrations; D025064:Sex Chromosome Disorders / Q000175:diagnosis / Q000235:genetics