Spinal subarachnoid hematomas and cerebral infarctions in Goodpasture's disease.
BACKGROUND
Goodpasture's disease with central nervous system involvement is extremely rare.


METHODS
We report a 62-year-old woman with Goodpasture's disease (GD) associated with the presence of perinuclear anti-neutrophil cytoplasmic antibodies, complicated by spinal subarachnoid hematomas and cerebral infarctions. In spite of aggressive treatment, the patient died.


CONCLUSIONS
GD and anti-neutrophil cytoplasmic antibodies vasculitis should be suspected in patients presented with renal insufficiency with spinal and/or brain involvement.
Taieb
G
G
Department of Neurology, CHU Nîmes, Hôpital Caremeau, Place du Pr Debré, Nîmes, France. taiebguillaume@gmail.com
Renard
D
D
Bonafe
A
A
Labauge
P
P
D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications* / Q000473:pathology; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood / Q000276:immunology; D002544:Cerebral Infarction / Q000150:complications* / Q000473:pathology; D005260:Female; D046649:Hematoma, Subdural, Spinal / Q000150:complications* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged
D019268:Antibodies, Antineutrophil Cytoplasmic