title: Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation.
abstract: The involvement of the small bowel in systemic forms of amyloidosis may be diffuse or very rarely focal. Some cases of focal amyloidomas of the duodenum and jejunum without extraintestinal manifestations have been reported. The focal amyloidomas consisted of extensive amyloid infiltration of the entire intestinal wall thickness. Radiological barium studies, ultrasound and computed tomography (CT) patterns of diffuse small bowel amyloidosis have been described: the signs are non-specific and may include small-bowel dilatation, symmetric bowel wall thickening, mesenteric infiltration, and mesenteric adenopathy. No data are available about the positron emission tomography (PET)/CT and magnetic resonance imaging (MRI) patterns of intestinal amyloidosis. We report two cases of small bowel amyloidosis: the former characterized by focal deposition of amyloid proteins exclusively within blood vessel walls of the terminal ileum, the latter characterized by diffuse intestinal involvement observed on MRI and PET/CT studies.
authors.affiliation: IBB CNR, Naples, Via Pansini 5, 80131, Naples, Italy. pierpamainenti@hotmail.com
authors.forename: Pier-Paolo
authors.initials: PP
authors.lastname: Mainenti
authors.forename: Sabrina
authors.initials: S
authors.lastname: Segreto
authors.forename: Marcello
authors.initials: M
authors.lastname: Mancini
authors.forename: Antonio
authors.initials: A
authors.lastname: Rispo
authors.forename: Immacolata
authors.initials: I
authors.lastname: Cozzolino
authors.forename: Stefania
authors.initials: S
authors.lastname: Masone
authors.forename: Ciro-Roberto
authors.initials: CR
authors.lastname: Rinaldi
authors.forename: Gerardo
authors.initials: G
authors.lastname: Nardone
authors.forename: Marco
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D007422:Intestines / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods