Molecularly imprinted polymers for sample preparation: a review.
In spite of the huge development of analytical instrumentation during last two decades, sample preparation is still nowadays considered the bottleneck of the whole analytical process. In this regard, efforts have been conducted towards the improvement of the selectivity during extraction and/or subsequent clean-up of sample extracts. Molecularly imprinted polymers (MIPs) are stable polymers with molecular recognition abilities, provided by the presence of a template during their synthesis and thus are excellent materials to provide selectivity to sample preparation. In the present review, the use of MIPs in solid-phase extraction and solid-phase microextraction as well as its recent incorporation to other extraction techniques such as matrix-solid phase dispersion and stir bar sorptive extraction, among others, is described. The advantages and drawbacks of each methodology as well as the future expected trends are discussed.
Turiel
Esther
E
Departamento de Medio Ambiente, INIA, Carretera de A Coruña km 7.5, E-28040 Madrid, Spain.
Martín-Esteban
Antonio
A
D053000:Analytic Sample Preparation Methods / Q000379:methods / Q000639:trends; D005591:Chemical Fractionation / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis; D005504:Food Analysis / Q000379:methods; D054802:Molecular Imprinting / Q000379:methods; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods / Q000639:trends; D052617:Solid Phase Microextraction / Q000295:instrumentation / Q000639:trends
D004785:Environmental Pollutants; D011108:Polymers