Asymmetric organocatalytic Michael addition of anthrone to enone.
Catalyzed by the bifunctional tertiary amino-thiourea organocatalyst derived from epicinchona alkaloid, the asymmetric Michael addition of anthrone to enone was achieved in high yield with excellent enantioselectivity.
Wu
Chunlin
C
Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Li
Wenjun
W
Yang
Juanjuan
J
Liang
Xinmiao
X
Ye
Jinxing
J
D000873:Anthracenes / Q000737:chemistry*; D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry; D000095322:Anthrones
D000873:Anthracenes; D002930:Cinchona Alkaloids; D003432:Cross-Linking Reagents; D007659:Ketones; D013890:Thiourea; C004522:anthrone; D000095322:Anthrones