title: DIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS.
abstract: We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional 'progressive' approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary sequence information to construct multiple protein alignments. Both programs are available through 'Göttingen Bioinformatics Compute Server' (GOBICS).
authors.affiliation: Wilhelm-Schickard-Institut für Informatik, University of Tübingen, Sand 13, 72076 Tübingen, Germany.
authors.forename: Amarendran R
authors.initials: AR
authors.lastname: Subramanian
authors.forename: Suvrat
authors.initials: S
authors.lastname: Hiran
authors.forename: Rasmus
authors.initials: R
authors.lastname: Steinkamp
authors.forename: Peter
authors.initials: P
authors.lastname: Meinicke
authors.forename: Eduardo
authors.initials: E
authors.lastname: Corel
authors.forename: Burkhard
authors.initials: B
authors.lastname: Morgenstern
mesh_terms: D020407:Internet; D017433:Protein Structure, Secondary; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein; D012984:Software