title: Case report: osteonecrosis of the mandible after laryngoscopy and endotracheal tube placement.
abstract: Four patients underwent laryngoscopy and general anesthesia surgery without apparent perioperative complications. Within days of their procedure, throat and mouth pain were reported and intraoral examination in all cases revealed exposed bone in the posterior mandible. The sequestra were easily removed and healing was uneventful. These lesions are likely associated with localized oral trauma during intubation causing periosteal damage, compromised blood supply, and subsequent bone necrosis. Because trauma to the mylohyoid ridge during intubation is likely more common than previously appreciated, anesthesiologists should be aware of this potential complication and refer patients to a specialist for management.
authors.affiliation: Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, 188 Longwood Ave., Boston, MA 02115, USA. soulafa_almazrooa@hsdm.harvard.ed
authors.forename: Soulafa A
authors.initials: SA
authors.lastname: Almazrooa
authors.forename: Kathleen
authors.initials: K
authors.lastname: Chen
authors.forename: Luigino
authors.initials: L
authors.lastname: Nascimben
authors.forename: Sook-Bin
authors.initials: SB
authors.lastname: Woo
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Treister
mesh_terms: D000368:Aged; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D015505:Chest Tubes; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects* / Q000295:instrumentation; D007828:Laryngoscopy / Q000009:adverse effects*; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use; D010020:Osteonecrosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology; D011859:Radiography; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D009067:Mouthwashes