title: Evidence-based guidelines for the pharmacological treatment of postmenopausal osteoporosis: a consensus document by the Belgian Bone Club.
abstract: Several drugs are available for the management of postmenopausal osteoporosis. This may, in daily practice, confuse the clinician. This manuscript offers an evidence-based update of previous treatment guidelines, with a critical assessment of the currently available efficacy data on all new chemical entities which were granted a marketing authorization. Osteoporosis is widely recognized as a major public health concern. The availability of new therapeutic agents makes clinical decision-making in osteoporosis more complex. Nation-specific guidelines are needed to take into consideration the specificities of each and every health care environment. The present manuscript is the result of a National Consensus, based on a systematic review and a critical appraisal of the currently available literature. It offers an evidence-based update of previous treatment guidelines, with the aim of providing clinicians with an unbiased assessment of osteoporosis treatment effect.
authors.affiliation: Department of Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: J-J
authors.initials: JJ
authors.lastname: Body
authors.forename: P
authors.initials: P
authors.lastname: Bergmann
authors.forename: S
authors.initials: S
authors.lastname: Boonen
authors.forename: Y
authors.initials: Y
authors.lastname: Boutsen
authors.forename: J-P
authors.initials: JP
authors.lastname: Devogelaer
authors.forename: S
authors.initials: S
authors.lastname: Goemaere
authors.forename: J-M
authors.initials: JM
authors.lastname: Kaufman
authors.forename: S
authors.initials: S
authors.lastname: Rozenberg
authors.forename: J-Y
authors.initials: JY
authors.lastname: Reginster
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D004164:Diphosphonates / Q000627:therapeutic use; D020847:Estrogen Receptor Modulators / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D019317:Evidence-Based Medicine / Q000379:methods; D005260:Female; D006801:Humans; D009942:Organometallic Compounds / Q000627:therapeutic use; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy*; D058866:Osteoporotic Fractures / Q000517:prevention & control; D013876:Thiophenes / Q000627:therapeutic use
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D020847:Estrogen Receptor Modulators; D009942:Organometallic Compounds; D013876:Thiophenes; C081587:strontium ranelate