Allosteric AKT inhibitors as a targeted cancer therapy.
Yun
Jihye
J
Ludwig Center for Cancer Genetics and Therapeutics, and Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA. yun1@jhmi.edu
D000494:Allosteric Regulation; D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000517:prevention & control*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D051057:Proto-Oncogene Proteins c-akt / Q000037:antagonists & inhibitors* / Q000378:metabolism
D047428:Protein Kinase Inhibitors; D051057:Proto-Oncogene Proteins c-akt