title: Synthesis and antifungal activities of new pyrazole derivatives via 1,3-dipolar cycloaddition reaction.
abstract: A series of cycloadducts--pyrazoles via 1,3-dipolar cycloaddition reactions of generated nitrilimines with N-(4-chloro-2-fluorophenyl)maleimide were described. The novel compounds synthesized were characterized by (1)H NMR, MS, and elemental analysis. The fungicidal tests showed that most of the title compounds exhibit significant fungicidal activities against Corynespora cassiicola.
authors.affiliation: Nankai University, Tianjin, China.
authors.forename: Chuan-Yu
authors.initials: CY
authors.lastname: Zhang
authors.forename: Xing-Hai
authors.initials: XH
authors.lastname: Liu
authors.forename: Bao-Lei
authors.initials: BL
authors.lastname: Wang
authors.forename: Su-Hua
authors.initials: SH
authors.lastname: Wang
authors.forename: Zheng-Ming
authors.initials: ZM
authors.lastname: Li
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018360:Crystallography, X-Ray; D003500:Cyclization; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000935:Antifungal Agents; D011720:Pyrazoles