High-molecular-weight polyquinoxaline-based helically chiral phosphine (PQXphos) as chirality-switchable, reusable, and highly enantioselective monodentate ligand in catalytic asymmetric hydrosilylation of styrenes.
A polyquinoxaline-based helical polymer ligand bearing both helical-sense-determining chiral side chains and coordinating diarylphosphino side chains exhibits solvent-dependent formation of P- or M-helical structures, with which either the S- or R-hydrosilylation product was obtained with high (>93% enantiomeric excess) enantioselectivities.
Yamamoto
Takeshi
T
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Yamada
Tetsuya
T
Nagata
Yuuya
Y
Suginome
Michinori
M