title: Performance of modularity maximization in practical contexts.
abstract: Although widely used in practice, the behavior and accuracy of the popular module identification technique called modularity maximization is not well understood in practical contexts. Here, we present a broad characterization of its performance in such situations. First, we revisit and clarify the resolution limit phenomenon for modularity maximization. Second, we show that the modularity function Q exhibits extreme degeneracies: it typically admits an exponential number of distinct high-scoring solutions and typically lacks a clear global maximum. Third, we derive the limiting behavior of the maximum modularity Qmax for one model of infinitely modular networks, showing that it depends strongly both on the size of the network and on the number of modules it contains. Finally, using three real-world metabolic networks as examples, we show that the degenerate solutions can fundamentally disagree on many, but not all, partition properties such as the composition of the largest modules and the distribution of module sizes. These results imply that the output of any modularity maximization procedure should be interpreted cautiously in scientific contexts. They also explain why many heuristics are often successful at finding high-scoring partitions in practice and why different heuristics can disagree on the modular structure of the same network. We conclude by discussing avenues for mitigating some of these behaviors, such as combining information from many degenerate solutions or using generative models.
authors.affiliation: Department of Physics, Swarthmore College, Swarthmore, Pennsylvania 19081, USA and Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, New Mexico 87501, USA. conkerll@gmail.com
authors.forename: Benjamin H
authors.initials: BH
authors.lastname: Good
authors.forename: Yves-Alexandre
authors.initials: YA
authors.lastname: de Montjoye
authors.forename: Aaron
authors.initials: A
authors.lastname: Clauset
mesh_terms: D008962:Models, Theoretical