[Ocular side effects of steroids and other immunosuppressive agents].
The increasing use of immunosuppressive (IS) drugs in transplants or in systemic diseases, implies a long period of treatment and to be aware of possible side effects. These drugs can be used alone or in combination with steroids. This review deals with the issue of ocular side effects of the most used IS drugs, including steroids. Data were collected from Medline using Pubmed software. We first describe specific complication of each drug and then conclude on major common toxicity represented by opportunistic infections and induced cancers.
Ballonzoli
Laurent
L
Service d'Opthalmologie, Nouvel Hôpital Civil, Strasbourg, France. laurent.ballonzoli@chru-strasbourg.fr
Bourcier
Tristan
T
D001379:Azathioprine / Q000009:adverse effects; D002386:Cataract / Q000139:chemically induced*; D003316:Corneal Diseases / Q000139:chemically induced*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives; D009369:Neoplasms / Q000139:chemically induced*; D009894:Opportunistic Infections / Q000139:chemically induced*
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D001379:Azathioprine