Sequential insertion of three different organometallics into a versatile building block containing a PNA backbone.
In the view of developing a synthetic route for the controlled insertion of distinct organometallic moieties into peptide nucleic acid (PNA) oligomers, a proof-of-principle study of the chemoselective insertion of three different organometallics into a building block containing both a PNA backbone and an alkyne side-chain is presented in this study.
Patra
Malay
M
Lehrstuhl für Anorganische Chemie I, Fakultät für Chemie und Biochemie, Ruhr-Universität Bochum, Gebäude NC 3 Nord, Universitätsstr. 150, 44801, Bochum, Germany.
Gasser
Gilles
G
Bobukhov
Dmytro
D
Merz
Klaus
K
Shtemenko
Alexander V
AV
Metzler-Nolte
Nils
N
D000480:Alkynes / Q000737:chemistry; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D020135:Peptide Nucleic Acids / Q000737:chemistry*; D012211:Rhenium / Q000737:chemistry
D000480:Alkynes; D009942:Organometallic Compounds; D020135:Peptide Nucleic Acids; D012211:Rhenium