Determination of non-HDL cholesterol in diabetic and hypertensive patients.
Recently, it has been suggested that non-high-density lipoprotein (non-HDL) cholesterol measure is a useful evaluation tool to assess heart disease death risk. The non-HDL cholesterol is defined as the value between total cholesterol and HDL - total cholesterol, and it involves the different fractions of lipoproteins: low-density lipoprotein, intermediate-density lipoprotein, and very low density lipoprotein, including highly atherogenic lipoproteins as very low density lipoprotein remnants. The purpose of this study was to compare the values of non-HDL cholesterol as a cardiovascular risk marker in a control population, and one diabetic and hypertensive. It was demonstrated that the mean values of non-HDL cholesterol in the diseased groups were higher than the values from the control group, whereas the low-density lipoprotein showed no marked difference in high-risk patients. Non-HDL cholesterol has shown to be a quick and simple way to estimate the risk of developing cardiovascular disease.
Contreras
Freddy
F
Medicine School, Physiopathology Department, Universidad Central de Venezuela,Caracas, Venezuela. sicontreras@cantv.net
Lares
Mary
M
Castro
Jorge
J
Velasco
Manuel
M
Rojas
Joselyn
J
Guerra
Xavier
X
Chacín
Maricarmen
M
Dowling
Victoria
V
Bermúdez
Valmore
V
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000209:etiology; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D055815:Young Adult
D015415:Biomarkers; D008076:Cholesterol, HDL; D002784:Cholesterol