Autologous matrix-induced chondrogenesis (AMIC). A one-step procedure for retropatellar articular resurfacing.
The objective of this technical note is to describe the autologous matrix induced chondrogenesis (AMIC) procedure and to evaluate its possible role for resurfacing of retropatellar cartilage defects. AMIC is a one-step procedure combining microfracturing with application of a collagen I/III membrane to protect the initial blood clot and to serve as a scaffold for the developing chondrocytes. A retrospective analysis of our experience in three patients followed for 18 months is presented.
Benthien
Jan Philipp
JP
Hip, Knee and Endoprosthetic Division, Department of Orthopaedic Surgery, Basel University Hospital, Basel, Switzerland. jbenthien@uhbs.ch
Behrens
Peter
P
D002358:Cartilage, Articular / Q000293:injuries*; D020219:Chondrogenesis / Q000502:physiology; D006801:Humans; D010329:Patella / Q000293:injuries*; D012189:Retrospective Studies; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds