title: Autologous matrix-induced chondrogenesis (AMIC). A one-step procedure for retropatellar articular resurfacing.
abstract: The objective of this technical note is to describe the autologous matrix induced chondrogenesis (AMIC) procedure and to evaluate its possible role for resurfacing of retropatellar cartilage defects. AMIC is a one-step procedure combining microfracturing with application of a collagen I/III membrane to protect the initial blood clot and to serve as a scaffold for the developing chondrocytes. A retrospective analysis of our experience in three patients followed for 18 months is presented.
authors.affiliation: Hip, Knee and Endoprosthetic Division, Department of Orthopaedic Surgery, Basel University Hospital, Basel, Switzerland. jbenthien@uhbs.ch
authors.forename: Jan Philipp
authors.initials: JP
authors.lastname: Benthien
authors.forename: Peter
authors.initials: P
authors.lastname: Behrens
mesh_terms: D002358:Cartilage, Articular / Q000293:injuries*; D020219:Chondrogenesis / Q000502:physiology; D006801:Humans; D010329:Patella / Q000293:injuries*; D012189:Retrospective Studies; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds