title: Malignant transformation of monostotic fibrous dysplasia in the mandible.
abstract: Malignant transformation of fibrous dysplasia (FD), which was first introduced by Coley and Steward is very rare. We present a case of malignant transformation of monostotic mandibular FD after 2 surgical excisions, 20 and 15 years ago, respectively. The treatment choice of FD is usually conservative. With the advanced surgical techniques, radical excisions followed by immediate reconstruction have been reported. However, the decision criteria are still controversial and we might think that radical treatment is a good method for recurrent lesions based on the recent literatures. The case discussed here is of sarcomatous transformation of a recurrent FD.
authors.affiliation: Departments of Oral & Maxillofacial Radiology, Kyung Hee University Medical Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
authors.forename: Gyu-Tae
authors.initials: GT
authors.lastname: Kim
authors.forename: Jung-Kyo
authors.initials: JK
authors.lastname: Lee
authors.forename: Byung-Joon
authors.initials: BJ
authors.lastname: Choi
authors.forename: Jin
authors.initials: J
authors.lastname: Kim
authors.forename: Sun-Hee
authors.initials: SH
authors.lastname: Han
authors.forename: Yong-Dae
authors.initials: YD
authors.lastname: Kwon
mesh_terms: D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D003287:Contrast Media; D005260:Female; D005358:Fibrous Dysplasia, Monostotic / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008336:Mandibular Diseases / Q000473:pathology* / Q000601:surgery; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012516:Osteosarcoma / Q000473:pathology* / Q000601:surgery; D011862:Radiography, Panoramic; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D005682:Gadolinium