Three new dioxopiperazine metabolites from a marine-derived fungus Aspergillus fumigatus Fres.
Three new dioxopiperazine metabolites (1-3), together with two known compounds, N-acetyltyramine (4) and cyclo-(Ala-Val) (5), were isolated from a marine-derived fungus Aspergillus fumigatus Fres. Their structures were established by spectroscopic methods. Their cytotoxic activities against the K562 cell line were preliminarily evaluated by the sulphorhodamine B (SRB) method.
Zhao
Wen Ying
WY
Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, PR China.
Zhu
Tian Jiao
TJ
Fan
Guo Tao
GT
Liu
Hong Bing
HB
Fang
Yu Chun
YC
Gu
Qian Qun
QQ
Zhu
Wei Ming
WM
D001232:Aspergillus fumigatus / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D000077489:Piperazine; D010879:Piperazines / Q000737:chemistry*
D010879:Piperazines; D000077489:Piperazine