title: Hyperperfusion in primary somatosensory region related to somatic hallucination in the elderly.
abstract: OBJECTIVE
  The purpose of the present study was to investigate the regional cerebral blood flow (rCBF) of patients with delusional disorder, somatic type (DDST) exhibiting somatic hallucination.
  
  
  METHODS
  Five patients diagnosed with DDST, as well as 20 control subjects, were examined. All subjects underwent technetium-99m ethyl cysteinate dimer brain perfusion single-photon emission computed tomography. Statistical analysis was performed with SPM5, using a two-sample t-test model to test the regional population effect on rCBF.
  
  
  RESULTS
  Patients with DDST had a significant increase in perfusion in the left post-central gyrus and the right paracentral lobule, both of which are involved in somatic sensory processing.
  
  
  CONCLUSIONS
  Somatic hallucination might be associated with increased perfusion in the primary somatosensory regions.
authors.affiliation: Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan. kiyotaka@nemotos.net
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Nemoto
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Mizukami
authors.forename: Takafumi
authors.initials: T
authors.lastname: Hori
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tachikawa
authors.forename: Miho
authors.initials: M
authors.lastname: Ota
authors.forename: Tohoru
authors.initials: T
authors.lastname: Takeda
authors.forename: Takashi
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuda
authors.forename: Takashi
authors.initials: T
authors.lastname: Asada
mesh_terms: D000368:Aged; D001921:Brain / Q000098:blood supply; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006212:Hallucinations / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020886:Somatosensory Disorders / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon