[Prognostic analysis on primary duodenal adenocarcinoma].
OBJECTIVE
To investigate the prognostic factors of primary duodenal adenocarcinoma.


METHODS
The medical records of 67 patients with primary duodenal adenocarcinoma treated in our hospital from January 1990 to December 2005 were retrospectively analyzed. Prognostic factors were analyzed by univariable and multivariable analysis.


RESULTS
Of the 67 patients, 38 underwent curative resection and 29 underwent palliative resection. The overall 5-year survival rate was 22.4%. The survival was significantly higher in patients who underwent curative resection (5-year survival 39.5%) than that in those who underwent palliative resection(5-year survival 0) (P<0.05). Univariable analysis showed that T-stage, nodal metastasis and tumor stage had significant negative effects on the survival of patients who underwent curative resection. However, multivariable analysis revealed that T-stage and nodal metastasis were significantly associated with survival.


CONCLUSIONS
Curative resection may improve the survival. T-stage and lymph nodes metastasis are associated with decreased survival.
Ke
Bin
B
Department of Gastric Cancer, Cancer Institute and Hospital of Tianjin Medical University, Tianjin 300060, China. kebinchina@hotmail.com
Liang
Han
H
Zhang
Ru-peng
RP
Wang
Xue-jun
XJ
Wang
Gang
G
Zhao
Jing-zhu
JZ
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D004379:Duodenal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult