A simple and efficient approach to the synthesis of 2-phenylquinazolines via sp(3) C-H functionalization.
A facile and novel approach to the synthesis of 2-phenylquinazolines was developed via a tandem reaction following sp(3) C-H functionalization. Twenty-five examples of 2-phenylquinazolines were obtained from easily available 2-aminobenzophenones and benzylic amines with good to excellent yields.
Zhang
Jintang
J
Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, Pr China.
Zhu
Dapeng
D
Yu
Chenmin
C
Wan
Changfeng
C
Wang
Zhiyong
Z