title: A randomised controlled trial of cognitive behaviour therapy for psychosis in a routine clinical service.
abstract: OBJECTIVE
  To evaluate cognitive behaviour therapy for psychosis (CBTp) delivered by non-expert therapists, using CBT relevant measures.
  
  
  METHODS
  Participants (N = 74) were randomised into immediate therapy or waiting list control groups. The therapy group was offered 6 months of therapy and followed up 3 months later. The waiting list group received therapy after waiting 9 months (becoming the delayed therapy group).
  
  
  RESULTS
  Depression improved in the combined therapy group at both the end of therapy and follow-up. Other significant effects were found in only one of the two therapy groups (positive symptoms; cognitive flexibility; uncontrollability of thoughts) or one of the two time points (end of therapy: general symptoms, anxiety, suicidal ideation, social functioning, resistance to voices; follow-up: power beliefs about voices, negative symptoms). There was no difference in costs between the groups.
  
  
  CONCLUSIONS
  The only robust improvement was in depression. Nevertheless, there were further encouraging but modest improvements in both emotional and cognitive variables, in addition to psychotic symptoms.
authors.affiliation: Department of Psychology, Kings College London, Institute of Psychiatry, De Crespigny Park, London, UK. emmanuelle.peters@kcl.ac.uk
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Peters
authors.forename: S
authors.initials: S
authors.lastname: Landau
authors.forename: P
authors.initials: P
authors.lastname: McCrone
authors.forename: M
authors.initials: M
authors.lastname: Cooke
authors.forename: P
authors.initials: P
authors.lastname: Fisher
authors.forename: C
authors.initials: C
authors.lastname: Steel
authors.forename: R
authors.initials: R
authors.lastname: Evans
authors.forename: K
authors.initials: K
authors.lastname: Carswell
authors.forename: K
authors.initials: K
authors.lastname: Dawson
authors.forename: S
authors.initials: S
authors.lastname: Williams
authors.forename: A
authors.initials: A
authors.lastname: Howard
authors.forename: E
authors.initials: E
authors.lastname: Kuipers
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001007:Anxiety; D015928:Cognitive Behavioral Therapy / Q000379:methods / Q000458:organization & administration; D003156:Community Mental Health Services / Q000458:organization & administration; D035061:Control Groups; D003863:Depression / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D011369:Professional-Patient Relations; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D012917:Social Adjustment; D059020:Suicidal Ideation; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents