title: Collagen membranes at immediate implants: a histomorphometric study in dogs.
abstract: OBJECTIVE
  To evaluate the influence of resorbable membranes on hard tissue alterations and osseointegration at implants placed into extraction sockets in a dog model.
  
  
  METHODS
  In the mandibular premolar region, implants were installed immediately into the extraction sockets of six Labrador dogs. Collagen-resorbable membranes were placed at the test sites, while the control sites were left uncovered. Implants were intended to heal in a submerged mode. After 4 months of healing, the animals were sacrificed, and ground sections were obtained for histomorphometric evaluation.
  
  
  RESULTS
  After 4 months of healing, a control implant was not integrated (n=5). Both at the test and at the control sites, bone resorption occurred. While the most coronal bone-to-implant contact was similar between the test and the control sites, the alveolar bone crest outline was maintained to a higher degree at the buccal aspect of the test sites (loss: 1.7 mm) compared with the control sites (loss: 2.2 mm).
  
  
  CONCLUSIONS
  The use of collagen-resorbable membranes at implants immediately placed into extraction sockets contributed to a partial (23%) preservation of the buccal outline of the alveolar process.
authors.affiliation: UNESP - Faculty of Dentistry of Araçatuba, São Paulo State University, SP, Brazil.
authors.forename: Marco
authors.initials: M
authors.lastname: Caneva
authors.forename: Daniele
authors.initials: D
authors.lastname: Botticelli
authors.forename: Luiz Antonio
authors.initials: LA
authors.lastname: Salata
authors.forename: Sérgio Luis
authors.initials: SL
authors.lastname: Scombatti Souza
authors.forename: Leandro
authors.initials: L
authors.lastname: Carvalho Cardoso
authors.forename: Niklaus Peter
authors.initials: NP
authors.lastname: Lang
mesh_terms: D020341:Absorbable Implants; D016301:Alveolar Bone Loss / Q000145:classification / Q000473:pathology; D000539:Alveolar Process / Q000473:pathology; D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D017267:Dental Prosthesis Design; D004285:Dogs; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008567:Membranes, Artificial; D023421:Models, Animal; D016348:Osseointegration / Q000502:physiology; D013524:Surgical Flaps; D013529:Surgical Wound Dehiscence / Q000209:etiology; D014025:Titanium / Q000737:chemistry; D020390:Tooth Socket / Q000473:pathology / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology; D015040:Zirconium / Q000737:chemistry
chemical_list: C106416:Bio-Gide; D001672:Biocompatible Materials; D015921:Dental Implants; D003764:Dental Materials; D008567:Membranes, Artificial; D003094:Collagen; D015040:Zirconium; D014025:Titanium