Preoperative chemotherapy to salvage the hand in a case of giant infantile hemangiopericytoma.
Hemangiopericytoma (HPC) is a rare vascular tumor arising from contractile cells around blood vessels, with the potential for malignant degeneration. Up to 10% of HPC occurs in children. Standard therapy for this tumor is surgical excision. We report the case of a 6-month-old infant with giant HPC involving the hand. Chemotherapy resulted in a decrease in tumor size, allowing for salvage of most of the hand and fingers. Preoperative chemotherapy should be considered in the care of HPC tumors involving the upper extremity in children.
Schneider
Lisa F
LF
Institute of Reconstructive Plastic Surgery and the Division of Pediatric Oncology, New York University Langone Medical Center, New York, NY 10016, USA.
Gardner
Sharon L
SL
Sharma
Sheel
S
D000671:Amputation, Surgical; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005260:Female; D006225:Hand; D006393:Hemangiopericytoma / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D023821:Limb Salvage / Q000379:methods*; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D011300:Preoperative Care; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*