[Mean systolic annular velocity and strain score index: new and non-invasive parameters for the evaluation of acute myocardial infarction patients].
OBJECTIVE
To evaluate the diagnostic value of mean annular velocity (MAV) and strain score index (SSI) for determination of the left ventricular systolic dysfunction in patients with first acute myocardial infarction (AMI).


METHODS
Seventy-one patients (55 male, mean age: 59+/-12 years) with first acute ST-elevation myocardial infarction and 30 healthy subjects were included in this cross-sectional and observational study. Echocardiography with tissue Doppler and strain analysis was performed during initial hospital admission. Peak systolic myocardial velocities were recorded from 4 different sites on the mitral annulus. A MAV value was calculated and the peak systolic strain values of 12 segments were measured and a mean SSI was calculated. ROC curve analysis was used in order to determine cut-off values for MAV and SSI.


RESULTS
The patients with AMI had a significantly reduced MAV compared with healthy subjects (5.52+/-1.78 cm/s vs 9.80+/-1.13 cm/s, p<0.001). In ROC analysis, a cut-off value of 8.41 cm/s (AUC 0.915, 95%CI 0.887-0.952, p<0.001) for MAV differentiated AMI patients from controls with 97.2% sensitivity and 93.3% specificity. The patients with AMI have also decreased SSI (11.23+/-2.83 vs 19.11+/-2.05, p<0.001). A cut-off value of 15.35% differentiated AMI patients from controls with 94.4% sensitivity and 100% specificity (ROC AUC 0.945, 95%CI 0.901-0.972, p<0.001). There was a good correlation between left ventricular EF and MAV (r=0.73, p<0.001) and SSI (r=0.66, p<0.001).


CONCLUSIONS
The patients with first myocardial infarction have decreased mean systolic annular velocity and mean systolic strain score index.
Hacettepe Universitesi Tip Fakültesi, Kardiyoloji Anabilim Dali, Ankara, Türkiye. doctorkaya@yahoo.com
Ergün Bariş
EB
Kaya
Necla
N
Ozer
Hakan
H
Aksoy
Onur Sinan
OS
Deveci
Erol
E
Tülümen
Sercan
S
Okutucu
Hikmet
H
Yorgun
Enver
E
Atalar
Serdar
S
Aksöyek
Ferhan
F
Ozmen
Kenan
K
Ovünç
Sirri
S
Kes
Hilmi
H
Ozkutlu
D000208:Acute Disease; D000368:Aged; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006321:Heart / Q000033:anatomy & histology / Q000503:physiopathology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D012016:Reference Values; D013599:Systole / Q000502:physiology*