Virulence of Escherichia coli B2 isolates from meat and animals in a murine model of ascending urinary tract infection (UTI): evidence that UTI is a zoonosis.
In vivo evidence of a connection between urinary tract infections (UTI) and foods is lacking. The virulence of 13 Escherichia coli B2 isolates from healthy animals and fresh meat was investigated in a murine model of ascending UTI. All isolates produced positive bladder cultures (10(2) to 10(7) CFU), and nine isolates produced positive kidney cultures (10(2) to 10(5) CFU).
Jakobsen
Lotte
L
National Center for Antimicrobials and Infection Control, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S, Denmark. lja@ssi.dk
Hammerum
Anette M
AM
Frimodt-Møller
Niels
N
D000818:Animals; D002645:Chickens / Q000382:microbiology*; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000302:isolation & purification* / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology* / Q000473:pathology; D005260:Female; D007668:Kidney / Q000382:microbiology; D008460:Meat / Q000382:microbiology*; D051379:Mice; D013552:Swine / Q000382:microbiology*; D001743:Urinary Bladder / Q000382:microbiology; D014552:Urinary Tract Infections / Q000382:microbiology* / Q000473:pathology; D014774:Virulence