Traction on the retina induced by saccadic eye movements in the presence of posterior vitreous detachment.
Posterior vitreous detachment is a fairly common condition in elderly people. Tractions exerted by the detached vitreous on the retina may result in retinal tears and detachments. We studied how these tractions can arise from saccadic eye movements. Numerical simulations have been performed on a two-dimensional model of the vitreous chamber within a rigid spherical sclera, subjected to prescribed finite-amplitude rotations about a vertical axis. The vitreous chamber was assumed to be split into two regions: one occupied by the detached vitreous, modeled as an elastic viscous solid, and the other occupied by the separated liquefied vitreous, modeled as a Newtonian fluid. At the interface between the two phases, we also considered the presence of the vitreous cortex, modeled as an elastic membrane. We tested several different configurations of the interface. In all cases, we found that eye rotations generate large tractions on the retina close to the attachment points of the membrane. Comparing them, we identified configurations of the vitreous detachment that exhibit higher tractions. We also investigated how the response to saccadic movements depends on some physical parameters, in particular on the rheological properties of the solid phase and the membrane. The numerical simulations show that the generated tractions may be of the same order of magnitude as the adhesive force between the retina and the pigment epithelium. Therefore, the model provides a sound physical justification for the hypothesis that saccadic movements, in the presence of posterior vitreous detachment, could be responsible for high tractions on the retina, which may trigger retinal tear formation.
Department of Civil, Environmental and Architectural Engineering, University of Genoa, Genoa, Italy. rodolfo.repetto@unige.it
R
R
Repetto
A
A
Tatone
A
A
Testa
E
E
Colangeli
D006801:Humans; D008954:Models, Biological; D009716:Numerical Analysis, Computer-Assisted; D012160:Retina / Q000503:physiopathology*; D012212:Rheology; D012399:Rotation; D012438:Saccades / Q000502:physiology*; D013997:Time Factors; D014143:Traction; D014822:Vitreous Body / Q000473:pathology / Q000503:physiopathology; D020255:Vitreous Detachment / Q000503:physiopathology*