Human cardiovascular effects of a new generation conducted electrical weapon.
OBJECTIVE
The conducted electrical weapon (CEW) is used by law enforcement to control potentially violent people. Much of the research in CEW safety has focused on the TASER X26, which uses a single deployment cartridge. New Generation CEW (NGCEW) technology has been developed that uses a different circuit and multiple cartridges that can be simultaneously deployed. The objective of this study is to examine the cardiovascular effects of the NGCEW in different deployment possibilities.


METHODS
This was a prospective study of human subjects during NGCEW training courses. Subjects received a NGCEW probe deployment to the frontal torso in 1 of 3 configurations: 2, 3,or 4 embedded probes and then underwent a 10-s exposure. Before and after vital signs, electrocardiograms (ECGs), and serum troponin I values were obtained. Real-time echocardiography was utilized before, during and after the exposure to evaluate heart rate and rhythm.


RESULTS
Initially, a 1st version NGCEW (NGCEWv1) that was in the final stages of manufacturer verification was used at the training courses. It had not been publicly released. During a NGCEWv1 exposure with 2 probes, there was an apparent brief episode of cardiac capture. Testing was halted and the manufacturer was notified. The device was redesigned and the study continued when a redesigned, 2nd version (NGCEWv2) was used. The NGCEW1 was studied in 8 subjects. The NGCEWv2 was studied in 45 subjects with no evidence of cardiac capture. There were no important post-exposure vital sign, troponin I or ECG changes found in any volunteers.


CONCLUSIONS
An apparent brief myocardial capture event occurred with the NGCEWv1. This device was not released and was redesigned. The NGCEWv2 appears to exhibit a reasonable degree of cardiac safety with frontal torso exposures and multiple probe combination configurations.
Ho
Jeffrey D
JD
Hennepin County Medical Center, Minneapolis, MN 55415, United States. jeffrey.ho@hcmed.org
Dawes
Donald M
DM
Reardon
Robert F
RF
Strote
Seth R
SR
Kunz
Sebastian N
SN
Nelson
Rebecca S
RS
Lundin
Erik J
EJ
Orozco
Benjamin S
BS
Miner
James R
JR
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000209:etiology*; D001794:Blood Pressure; D004452:Echocardiography; D004558:Electric Stimulation / Q000295:instrumentation*; D004562:Electrocardiography; D004867:Equipment Design; D005260:Female; D006339:Heart Rate; D006801:Humans; D035846:Law Enforcement; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood; D054041:Weapons
D019210:Troponin I; D010100:Oxygen