Rosuvastatin-induced thrombocytopenia.
Rosuvastatin, a statin indicated for patients with primary hypercholesterolemia, mixed dyslipidemia and familial hypercholesterolemia, is well tolerated by most patients. Its most common adverse effects are gastrointestinal derangement, muscle aches and hepatitis. One rare complication of statin treatment is severe thrombocytopenia. The case of a 65-year-old patient who developed severe thrombocytopenia while on rosuvastatin is presented, in addition to a review of the literature.
Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, Attikon University General Hospital, Haidari, Athens, Greece.
Ioannis
I
Vrettos
Sotiris
S
Papageorgiou
Christina
C
Economopoulou
Vasiliki
V
Pappa
Panagiotis
P
Tsirigotis
Nikolaos
N
Tountas
Theofanis
T
Economopoulos
John
J
Dervenoulas
D000368:Aged; D050171:Dyslipidemias / Q000188:drug therapy; D005260:Female; D005464:Fluorobenzenes / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D011743:Pyrimidines / Q000009:adverse effects* / Q000627:therapeutic use; D000068718:Rosuvastatin Calcium; D013449:Sulfonamides / Q000009:adverse effects* / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis
D005464:Fluorobenzenes; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011743:Pyrimidines; D013449:Sulfonamides; D000068718:Rosuvastatin Calcium