Electrochemical method for the determination of enantiomeric excess of binol using redox-active boronic acids as chiral sensors.
A chiral ferrocene-based boronic acid interacts with (R)- and (S)-Binol to form two complexes that exhibit significantly different ferrocene-based electrode potentials. This difference in redox behavior can be exploited to demonstrate in principle how high levels of enantiomeric excess in a mixture of enantiomers can be quantified and read-out using an electrochemical method.
School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Giorgio
G
Mirri
Steven D
SD
Bull
Peter N
PN
Horton
Tony D
TD
James
Louise
L
Male
James H R
JH
Tucker