Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation.
With the constant advent of new developments and modifications in immunosuppressive regimens, clinicians are responsible for providing pregnancy counseling in all pre- and post-transplant recipients of childbearing age. As individual physicians and centers accrue experience with these major therapeutic decisions, it is critical that both positive and negative outcomes be reported in appropriate settings-symposia, meetings, publications, and registries. Future analyses from the NTPR are directed at potential effects of newer immunosuppressive regimens, not only from immediate exposure, but also from continued exposures such as may occur from breastfeeding. As the registry study design allows for contact between registry staff and recipients and their health care providers, efforts are ongoing to analyze long-term outcomes of parent and child. Continued close collaboration among specialists will help to better identify potential pregnancy risks in these populations, particularly as new immunosuppressive agents are developed. Therefore, centers are encouraged to report all pregnancy exposures in transplant recipients to the NTPR.
Dept of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Lisa A
LA
Coscia
Serban
S
Constantinescu
Michael J
MJ
Moritz
Adam
A
Frank
Carlo B
CB
Ramirez
Warren L
WL
Maley
Cataldo
C
Doria
Carolyn H
CH
McGrory
Vincent T
VT
Armenti
D001724:Birth Weight; D002585:Cesarean Section / Q000706:statistics & numerical data; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007231:Infant, Newborn; D050498:Live Birth; D016377:Organ Transplantation / Q000502:physiology*; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012042:Registries; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014481:United States
D007166:Immunosuppressive Agents