Synthesis of reaction-ready 6,6'-biindole and 6,6'-biisatin via palladium(II)-catalysed intramolecular C-H functionalisation.
The first synthesis of a 6,6'-biindole and 6,6'-biisatin scaffold is reported with the penultimate step being the formation of the di-heterocyclic ring by Pd(II)-catalysed intramolecular C-H functionalisation and Sandmeyer cyclisation, respectively.
Gamble
Allan B
AB
School of Chemistry, University of Wollongong, 2522, Wollongong, Australia.
Keller
Paul A
PA
D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry*
D007211:Indoles; D010165:Palladium