Does the timing of mock embryo transfer trial improve implantation in intracytoplasmic sperm injection cycles?
OBJECTIVE
To determine if endometrial trauma during embryo transfer trials (ETTs) improves implantation and clinical pregnancy rates in intracytoplasmic sperm injection treatment cycles.


METHODS
One-hundred fifty women undergoing their first IVF treatment were included in a prospective randomised study in a University hospital clinic. ETTs were performed either on day 21 of the previous cycle, or on day 6 of the controlled ovarian hyperstimulatin (COH) cycle, or conducted at least two cycles before COH cycle. Clinical pregnancy and implantation rates were compared between the groups.


RESULTS
There was no difference between the groups in terms of clinical pregnancy or implantation rates.


CONCLUSIONS
Endometrial trauma by ETTs performed either during the preceding cycle or on day 6 of the COH cycle does not improve pregnancy rates.
Department of Obstetrics and Gynecology, Marmara University School of Medicine, Istanbul, Turkey. tevfik.yoldemir@gmail.com
Tevfik
T
Yoldemir
Mithat
M
Erenus
D000328:Adult; D010064:Embryo Implantation / Q000502:physiology*; D004624:Embryo Transfer / Q000379:methods* / Q000706:statistics & numerical data; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007246:Infertility / Q000097:blood / Q000628:therapy; D008297:Male; D010919:Placebos; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods* / Q000706:statistics & numerical data; D013997:Time Factors; D055815:Young Adult
D010919:Placebos; D004958:Estradiol