Vitamin D: extraskeletal health.
Vitamin D deficiency is the most common nutritional deficiency and likely the most common medical condition in the world. The major cause of vitamin D deficiency has been the lack of appreciation that the body requires 5- to 10-fold higher intakes than is currently recommended by health agencies. There is now overwhelming and compelling scientific and epidemiologic data suggesting that the human body requires a blood level of 25(OH)D above 30 ng/mL for maximum health. To increase the blood level to the minimum 30 ng/mL requires the ingestion of at least 1000 IU of vitamin D per day for adults. In general, there is no downside to increasing either a child's or adult's vitamin D intake.
Holick
Michael F
MF
Section of Endocrinology, Nutrition, and Diabetes, Department of Medicine, Vitamin D, Skin and Bone Research Laboratory, Boston University School of Medicine, Boston University Medical Center, Boston, MA 02118, USA. mfholick@bu.edu
D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000517:prevention & control; D002319:Cardiovascular System / Q000187:drug effects; D003060:Cod Liver Oil / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000517:prevention & control; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D050417:Insulin-Secreting Cells / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000517:prevention & control; D009369:Neoplasms / Q000188:drug therapy / Q000517:prevention & control; D018673:Nutrition Policy; D009751:Nutritional Requirements; D011565:Psoriasis / Q000188:drug therapy; D018167:Receptors, Calcitriol / Q000378:metabolism; D013472:Sunlight; D014376:Tuberculosis / Q000188:drug therapy / Q000517:prevention & control; D014807:Vitamin D / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use*; D014808:Vitamin D Deficiency / Q000378:metabolism*
D018167:Receptors, Calcitriol; D014807:Vitamin D; D003060:Cod Liver Oil