"I feel like I am 100 years old!" managing arthralgias from aromatase inhibitors.
Aromatase inhibitors (AIs) are recommended for the treatment of estrogen-sensitive breast cancer in postmenopausal women and provide a superior risk reduction compared to five years of tamoxifen alone. Arthralgias, a common side effect of AIs, may adversely affect quality of life, treatment adherence, and persistence. Early discontinuation of AIs may result in an inadequate clinical response. Over-the-counter analgesics, exercise, and drug holidays are common strategies used to manage arthralgias, however few interventions are evidence-based. Patients experiencing arthralgias may experience distress and, therefore would benefit from ongoing nursing support. When caring for patients with arthralgias, nurses should assess for potential modifiable risk factors, recommend lifestyle changes and/or pharmacologic interventions, and offer ongoing education and follow-up.
Winters
Loren
L
Gillette Center for Breast Cancer, Massachusetts General Hospital, Boston, USA. lwinters@partners.org
Habin
Karleen
K
Flanagan
Jane
J
Cashavelly
Barbara J
BJ
D047072:Aromatase Inhibitors / Q000009:adverse effects*; D018771:Arthralgia / Q000139:chemically induced / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged
D047072:Aromatase Inhibitors