Spontaneous HBsAg seroconversion after severe flare of chronic hepatitis B infection.
The results of the acute exacerbations of hepatitis B virus are varied from silent to severe acute hepatitis. HBsAg seroconversion induced by either antiviral drugs or occurred spontaneously, as a targeted end point of HBV infection management is infrequent. The affect of the severe hepatitic flare on HBsAg seroconversion was reported before, however the predictive markers of HBsAg seroconversion are not clear yet. The reasons of the spontaneously HBV re-activations, or its usual results are not known well. We, herein reported a case, with the high serum HBV DNA titer during an acute spontaneously induced severe exacerbation of HBV infection which spontaneously resulted in total HBV recovery.
Diskapi Yildirim Beyazit Education and Research Hospital, Department of Gastroenterology, Ankara, Turkey. drakifa@yahoo.com
Akif
A
Altinbas
Ilhami
I
Yüksel
Melih
M
Pamukcu
Fuat
F
Ekiz
Omer
O
Basar
Osman
O
Yüksel
D000328:Adult; D004279:DNA, Viral / Q000097:blood; D006510:Hepatitis B Antibodies / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology*; D019694:Hepatitis B, Chronic / Q000175:diagnosis*; D006801:Humans; D008297:Male; D012720:Severity of Illness Index; D019562:Viral Load; D014775:Virus Activation
D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens