The engineering of an orally active conotoxin for the treatment of neuropathic pain.
Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.
Richard J
RJ
Clark
Jonas
J
Jensen
Simon T
ST
Nevin
Brid P
BP
Callaghan
David J
DJ
Adams
David J
DJ
Craik
D000818:Animals; D002121:Calcium Channel Blockers / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D020916:Conotoxins / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D015394:Molecular Structure; D009437:Neuralgia / Q000188:drug therapy*; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D011487:Protein Conformation; D051381:Rats
D002121:Calcium Channel Blockers; D020916:Conotoxins; D010455:Peptides