Ebola and marburg hemorrhagic fever.
Ebola and Marburg viruses cause a severe viral hemorrhagic fever disease mainly in Sub-Saharan Africa. Although outbreaks are sporadic, there is the potential for filoviruses to spread to other continents unintentionally because of air travel or intentionally because of bioterrorism. This article discusses the natural history, epidemiology, and clinical presentation of patients infected with Ebola and Marburg viruses. Clinicians in the United States should be aware of the symptoms of these viral infections in humans and know the appropriate procedures for contacting local, state, and national reference laboratories in the event of a suspected case of filoviral hemorrhagic fever.
University of Pittsburgh, Center for Vaccine Research, PA 15261, USA. hartman2@pitt.edu <hartman2@pitt.edu>
Amy L
AL
Hartman
Jonathan S
JS
Towner
Stuart T
ST
Nichol
D000818:Animals; D003937:Diagnosis, Differential; D016563:Filoviridae / Q000145:classification / Q000235:genetics; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D008379:Marburg Virus Disease / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D010802:Phylogeny; D014765:Viral Vaccines / Q000276:immunology
D014765:Viral Vaccines