Signal-on electrochemiluminescence biosensor for thrombin based on target-induced conjunction of split aptamer fragments.
A highly sensitive and selective electrochemiluminescence biosensor for detection of thrombin based on the strategy of target-induced conjunction of split aptamer fragments was developed.
Lin
Zhenyu
Z
Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China.
Chen
Lifen
L
Zhu
Xi
X
Qiu
Bin
B
Chen
Guonan
G
D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry / Q000378:metabolism*; D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry / Q000379:methods*; D006801:Humans; D049449:Luminescence; D053758:Nanoparticles / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000737:chemistry; D013917:Thrombin / Q000032:analysis*
D052157:Aptamers, Nucleotide; D012822:Silicon Dioxide; D012428:Ruthenium; D013917:Thrombin