Ultrasound measurement of bladder wall thickness in different forms of detrusor overactivity.
OBJECTIVE
Aims of this study were to compare the ultrasound measurement of bladder wall thickness (BWT) in women with different urodynamic diagnosis and to correlate BWT to the different urodynamic findings of detrusor overactivity (DO).


METHODS
Two hundred forty seven women with urinary symptoms have been prospectively enrolled. Urodynamics and transvaginal ultrasound BWT were performed. Patients were divided into four urodynamic subgroups. BWT of women with DO was compared with the BWT of any other subgroup.


RESULTS
Women with DO had a BWT value significantly higher (p < 0.0001). A cut-off of 6.5 mm for BWT had a positive predictive value of 100% for all DO. We use ROC curves to analyze the BWT for urgency urinary incontinence (AUC 0.645 95% CI 0.57-0.72) and the BWT for "pure DO" (AUC 0.702 95% CI 0.64-0.76) and for "all DO" (AUC 0.704 95% CI 0.64-0.77) vs other urodynamic diagnoses.


CONCLUSIONS
The ultrasound BWT showed a highly significant association with DO. However, the performance of this test cannot currently replace urodynamic testing.
Dept of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Piazza Biroldi 1, Varese 21100, Italy. mauserati@hotmail.com
Maurizio
M
Serati
Stefano
S
Salvatore
Elena
E
Cattoni
Marco
M
Soligo
Antonella
A
Cromi
Fabio
F
Ghezzi
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D014463:Ultrasonography; D001743:Urinary Bladder / Q000000981:diagnostic imaging* / Q000473:pathology*; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D014549:Urinary Incontinence / Q000150:complications