[Medication adherence of a sample of hypertensive patients in the region of Sfax (Tunisia)].
OBJECTIVE
Medication noncompliance is one of the daily problems of the physician. Improving the medication adherence allows better management of hypertension. The aim of this work was to determine the level of compliance for patients with hypertension and to identify factors that determine compliance.


METHODS
A cross-sectional study was carried out among a sample of hypertensive patients attending general and specialist practitioners in public or private clinics of Sfax. Two hundred and seventy-three participants had accepted to be interviewed. Patients were identified as noncompliants using a questionnaire developed by the Comité de lutte contre l'hypertension artérielle (CFLHTA).


RESULTS
Non-compliance rate was 63.4%. The low level of education was associated with a lower adherence. The monotherapy, the once-daily regimen with fewer number of tablets were associated with a better adherence (p<10(-6)). The welcome and the availability of drugs in the public clinic affect positively the adherence of patients (p<0.0002). A patient very satisfied with his consultation and the explanation given by the doctor about his illness and its treatment had a better adherence (p<0.00003).


CONCLUSIONS
Our study had demonstrated a low compliance with antihypertensive drug therapy. Tunisian health care system should elaborate a management plan which takes into account our particular predictors of compliance to improve adherence to antihypertensive medication.
Laboratoire de pharmacologie, faculté de médecine de Sfax, 3029 Sfax, Tunisie. ghozzihanne2001@yahoo.fr
H
H
Ghozzi
M
M
Kassis
A
A
Hakim
Z
Z
Sahnoun
A
A
Abderrahmen
R
R
Abbes
S
S
Maalej
S
S
Hammami
L
L
Hajkacem
K
K
Zeghal
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D014416:Tunisia; D016903:Drug Monitoring