A protease-based strategy for the controlled release of therapeutic peptides.
Li
Hongjian
H
Department of Biotechnology, Jinan University, Guangzhou, Guangdong 510632, China. tlihj@jnu.edu.cn
Ma
Yi
Y
Chen
Ying
Y
Sang
Yanxia
Y
Zhou
Tianhong
T
Qiu
Meilan
M
Huang
Xiumei
X
Zhou
Cindy
C
Su
Zhengding
Z
D000595:Amino Acid Sequence; D052216:Glucagon-Like Peptide 1 / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D006207:Half-Life; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D010447:Peptide Hydrolases / Q000378:metabolism*; D010455:Peptides / Q000008:administration & dosage* / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D012709:Serum Albumin / Q000737:chemistry; D013917:Thrombin / Q000378:metabolism
D007004:Hypoglycemic Agents; D010455:Peptides; D012709:Serum Albumin; D052216:Glucagon-Like Peptide 1; D010447:Peptide Hydrolases; D013917:Thrombin