Acquired hemophilia as a paraneoplastic manifestation of gastrointestinal stromal tumor.
Acquired hemophilia is a severe hemorrhagic diathesis characterized by the emergence of anti-factor VIII inhibiting antibodies. It is rarely seen in certain types of cancers as a paraneoplastic syndrome. The case of a 73-year-old patient who developed acquired hemophilia during the course of treatment for a gastrointestinal stromal tumor is presented. A discussion of the diagnosis and treatment of acquired hemophilia as a paraneoplastic syndrome is also included.
Department of Clinical Sciences, Saba University School of Medicine, Devens, MA, USA. b.kumar@saba.edu
Bharat
B
Kumar
D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology*; D001780:Blood Coagulation Tests; D017809:Fatal Outcome; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D046152:Gastrointestinal Stromal Tumors / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology*; D011379:Prognosis