Bacille Calmette-Guérin osteomyelitis of the proximal femur.
All newborns in Hong Kong are given bacille Calmette-Guérin vaccinations. Reported complications include formation of regional and extra-regional localised abscesses, osteomyelitis, and lymphadenitis. Several cases of bacille Calmette-Guérin osteomyelitis have been reported in Europe, but there are few reports of this in Asia. To the author's knowledge, this is the first case report of bacille Calmette-Guérin osteomyelitis in Hong Kong. Bacille Calmette-Guérin osteomyelitis, although rare, should be kept in mind as a potential complication of bacille Calmette-Guérin vaccination. Clinical suspicion, early diagnosis using an image-guided tissue biopsy and polymerase chain reaction study, and early commencement of chemotherapy are key to the effective management of this problem.
Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Shatin, Hong Kong. lewis@graduate.hku.hk
P K
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Chan
Bobby K W
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Ng
C Y
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Wong
D001500:BCG Vaccine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005269:Femur; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000209:etiology*; D016133:Polymerase Chain Reaction
D001500:BCG Vaccine