Pure naratriptan-induced ischemic colitis: a case report.
A 60-year-old female with sudden onset of abdominal pain and hematochezia was diagnosed with histology-proven ischemic colitis. She used naratriptan on a regular basis for migraine. By exclusion of other causes for colonic ischemia and the absence of cardiovascular risk factors, naratriptan was considered the causal agent. Discontinuation resulted in a complete clinical recovery. With the increasing use of triptans, health care providers should be aware of the possible serious ischemic events associated with these drugs.
Westgeest
Hans M
HM
Departments of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands. hm.westgeest@vumc.nl
Akol
Halil
H
Schreuder
Tim C M A
TC
D017091:Colitis, Ischemic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D010880:Piperidines / Q000009:adverse effects*; D014363:Tryptamines / Q000009:adverse effects*; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
D010880:Piperidines; D014363:Tryptamines; D014662:Vasoconstrictor Agents; C106783:naratriptan