Pleural granuloma mimicking malignancy 42 years after slurry talc injection for primary spontaneous pneumothorax.
BACKGROUND
Talc poudrage is considered a safe pleurodesis technique to improve the results of video-assisted thoracoscopic surgery in cases of primary spontaneous pneumothorax (PSP).


METHODS
We report the case of a patient with left pleural pseudo-nodular plaque and a high metabolic rate upon PET scan suspected for malignancy, occurring 42 years after slurry talc injection for conservative treatment of PSP. The patient presented with coughing, chest pain and weight loss. Thoracotomy was required to obtain a diagnosis and perform a complete pleurectomy.


RESULTS
Histology was conclusive for pleural talc granuloma.


CONCLUSIONS
Indications and possible complications of talc use in young patients with PSP, and the management of possible consequent pleural lesions suspected for malignancy, need to be investigated.
Tenconi
S
S
Thoracic Surgery Unit, University Hospital of Siena, Siena, Italy. tenconi.sara @ gmail.com
Luzzi
L
L
Paladini
P
P
Voltolini
L
L
Gallazzi
M S
MS
Granato
F
F
Gotti
G
G
D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D015745:Granuloma, Foreign-Body / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis; D008875:Middle Aged; D010995:Pleural Diseases / Q000175:diagnosis* / Q000209:etiology*; D010997:Pleural Neoplasms / Q000175:diagnosis; D018700:Pleurodesis / Q000009:adverse effects* / Q000379:methods; D011030:Pneumothorax / Q000628:therapy*; D019275:Radiopharmaceuticals; D013627:Talc / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D013627:Talc