Pure naratriptan-induced ischemic colitis: a case report.
A 60-year-old female with sudden onset of abdominal pain and hematochezia was diagnosed with histology-proven ischemic colitis. She used naratriptan on a regular basis for migraine. By exclusion of other causes for colonic ischemia and the absence of cardiovascular risk factors, naratriptan was considered the causal agent. Discontinuation resulted in a complete clinical recovery. With the increasing use of triptans, health care providers should be aware of the possible serious ischemic events associated with these drugs.
Departments of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands. hm.westgeest@vumc.nl
Hans M
HM
Westgeest
Halil
H
Akol
Tim C M A
TC
Schreuder
D017091:Colitis, Ischemic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D010880:Piperidines / Q000009:adverse effects*; D014363:Tryptamines / Q000009:adverse effects*; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
D010880:Piperidines; D014363:Tryptamines; D014662:Vasoconstrictor Agents; C106783:naratriptan