Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players.
Oxidative stress occurs during maximal exercise, perhaps as a result of increased consumption of oxygen. Vitamins C and E can overcome the effects of antioxidants in exercise. We investigated the effects of supplementation with a combination of vitamin C and E (VCE) on blood lipid peroxidation (LP) and antioxidant levels following maximal training in basketball players.Blood samples were taken from 14 players (group A) and divided into two subgroups namely maximal training (group B) and maximal training plus VCE groups (group C). Group B maximally exercised for 35 days. VCE was supplemented to group C for 35 days and blood samples were taken from group B and C. Plasma and hemolyzed erythrocyte samples were obtained from the players.Erythrocyte glutathione peroxidase (GSH-Px) activity and plasma vitamin E concentration were lower in group B than in group A, whereas plasma and erythrocyte LP levels were higher in group B than in group A. Plasma vitamin A, vitamin E, erythrocyte GSH-Px, and reduced glutathione (GSH) values were higher in group C than in groups A and B although LP levels in plasma and erythrocytes were lower in group C than in group A and B. beta-Carotene values did not change in the three groups.In conclusion, VCE supplementation in maximal exercising basketball players may strengthen the antioxidant defense system by decreasing reactive oxygen species (ROS).
Naziroğlu
Mustafa
M
Department of Biophysics, Suleyman Demirel University, Isparta, Turkey. mnaziroglu@med.sdu.edu.tr <mnaziroglu@med.sdu.edu.tr>
Kilinç
Fatih
F
Uğuz
Abdulhadi Cihangir
AC
Celik
Omer
O
Bal
Ramazan
R
Butterworth
Peter J
PJ
Baydar
Metin Lütfi
ML
D000284:Administration, Oral; D000293:Adolescent; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D001490:Basketball; D004912:Erythrocytes / Q000201:enzymology; D015444:Exercise; D005978:Glutathione / Q000097:blood; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D014801:Vitamin A / Q000097:blood; D014810:Vitamin E / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D019207:beta Carotene / Q000097:blood
D000975:Antioxidants; D019207:beta Carotene; D014801:Vitamin A; D014810:Vitamin E; D005979:Glutathione Peroxidase; D005978:Glutathione; D001205:Ascorbic Acid