Master regulator or readout: the wisdom of distributed control. Focus on "Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes".
Department of Integrative Biology, University of California, Berkeley, California 94720-3140, USA. gbrooks@berkeley.edu
George A
GA
Brooks
D000818:Animals; D002460:Cell Line; D004579:Electron Transport / Q000502:physiology*; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice; D018485:Muscle Fibers, Skeletal / Q000378:metabolism*; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D019289:Pyruvic Acid / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D013379:Substrate Specificity / Q000502:physiology; D014157:Transcription Factors / Q000037:antagonists & inhibitors / Q000096:biosynthesis*
D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; C501429:Ppargc1a protein, rat; D016601:RNA-Binding Proteins; D014157:Transcription Factors; D019289:Pyruvic Acid