Comparison of self-reported cutaneous allodynia and brushing allodynia during migraine attacks.
This study compares the results of brushing allodynia (BA) during migraine attacks to those of self-reported cutaneous allodynia. We recruited 100 patients (20 with chronic migraine, 80 with episodic migraine) and performed a gauze-brushing test to detect BA. A previous experience of cutaneous allodynia was queried. Seventeen patients reported having allodynia before, whereas 22 patients exhibited BA. The frequency of self-reported allodynia (12.5% vs. 35.0%, p = .040) but not BA (21.3% vs. 25.0%, p = .765) differed between patients with episodic migraine and those chronic migraine. Patients with aura (N = 8) had a higher frequency of both self-reported allodynia (62.5% vs. 12.2%, p = .003) and BA (87.5% vs. 17.6%, p < .001) than those without aura (N = 92). Some allodynia symptoms, including avoidance of washing hair, touching the head, combing hair and lying on the site of head pain, were associated with BA (all p < .05). Our study showed that BA during migraine attacks correlated well with prior allodynia symptoms. The frequencies of BA and self-reported allodynia depend on the composition of different migraine subtypes and the timing of the gauze-brushing test.
Chou
Chi-Hsiang
CH
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Fuh
Jong-Ling
JL
Wu
Jaw-Ching
JC
Wang
Shuu-Jiun
SJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications*; D011795:Surveys and Questionnaires; D014110:Touch; D055815:Young Adult