Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa.
OBJECTIVE
To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in sub-Saharan Africa.


METHODS
Cross-sectional survey conducted in eight adult HIV treatment centres from Benin, Côte d'Ivoire and Mali. Participants and measurements During a 4-week period, health workers administered the Alcohol Use Disorders Identification Test to HAART-treated patients and assessed treatment adherence using the AIDS Clinical Trials Group follow-up questionnaire.


RESULTS
A total of 2920 patients were enrolled with a median age of 38 years [interquartile range (IQR) 32-45 years] and a median duration on HAART of 3 years (IQR 1-4 years). Overall, 91.8% of patients were identified as adherent to HAART. Non-adherence was associated with current drinking [odds ratio (OR) 1.4; 95% confidence interval (CI) 1.1-2.0], hazardous drinking (OR 4.7; 95% CI 2.6-8.6) and was associated inversely with a history of counselling on adherence (OR 0.7; 95% CI 0.5-0.9).


CONCLUSIONS
Alcohol consumption and hazardous drinking is associated with non-adherence to HAART among HIV-infected patients from West Africa. Adult HIV care programmes should integrate programmes to reduce hazardous and harmful drinking.
HIV Epidemiology, INSERM CRE U 897, Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux 2, France. antoine.jaquet@isped.u-bordeaux2.fr
Antoine
A
Jaquet
Didier K
DK
Ekouevi
Jules
J
Bashi
Maiga
M
Aboubakrine
Eugène
E
Messou
Moussa
M
Maiga
Hamar Alassane
HA
Traore
Marcel Djimon
MD
Zannou
Calixte
C
Guehi
Franck Olivier
FO
Ba-Gomis
Albert
A
Minga
Gérard
G
Allou
Serge Paul
SP
Eholie
Emmanuel
E
Bissagnene
Annie J
AJ
Sasco
Francois
F
Dabis
D000293:Adolescent; D000328:Adult; D000354:Africa, Western / Q000453:epidemiology; D000428:Alcohol Drinking / Q000453:epidemiology*; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D003376:Counseling / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D011795:Surveys and Questionnaires; D055815:Young Adult
D044966:Anti-Retroviral Agents