[Clinical and epidemiological features and HLA association in patients with pars planitis].
OBJECTIVE
Epidemiological studies on North American patients reported an association between HLA DR15 and pars planitis. This association has not been studied in the Spanish population. The objectives of the present study were to describe the clinical and epidemiological features of patients with pars planitis diagnosed in our hospital as well as the prevalence of multiple sclerosis and HLA class I and II.


METHODS
Twenty four patients with pars planitis were identified among 226 patients with uveitis diagnosed in the Ophtahlmology Department of our center from January 1992 to October 2006. Twenty four patients and 194 healthy controls underwent HLA A, B and DR genotyping.


RESULTS
The most frequent complication was cystic macular edema. Most patients needed many medical treatments. No statistical association was found between pars planitis and HLA.


CONCLUSIONS
Epidemiological data were consistent with previously reported studies. There appears to be no association between the occurrence of pars planitis and HLA DR 15 or other known HLA genotypes in Spanish patients. However, the small sample size could have limited the power of this study.
Servicio de Oftalmología. Hospital de San Juan de Dios del Aljarafe, Bormujos, Sevilla, España. manbeu@gmail.com
María Eugenia
ME
Mantrana-Bermejo
Trinidad
T
Rueda-Rueda
José
J
Bernabeu-Wittel
Francisca
F
González-Escribano
Francisco
F
García-Hernández
Julio
J
Sánchez-Román
D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D008297:Male; D015868:Pars Planitis / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D012189:Retrospective Studies; D055815:Young Adult
D006680:HLA Antigens