Radiotherapy. Hypofractionation for breast cancer--clinical implications.
A recent landmark study reported the long-term results that compared a standard course of whole-breast irradiation (25 treatments over 5 weeks) with a hypofractionated course of radiation (16 treatments over 3.5 weeks) in patients with early-stage, node-negative breast cancer. The trial demonstrated equivalence of results with respect to overall survival,local control, toxicity and cosmetic outcomes.
Department of Radiation Oncology, UMDNJ Robert Wood Johnson Medical School, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08901, USA. hafftybg@umdnj.edu
Bruce G
BG
Haffty
D001940:Breast / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D016896:Treatment Outcome