Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant.
Recently, a new genus of Anaplasmataceae termed "Candidatus Neoehrlichia" was discovered in ticks and rodents. Here, we report on two patients who suffered from febrile bacteremia due to "Candidatus Neoehrlichia mikurensis" associated with thrombotic or hemorrhagic events. 16S rRNA and groEL gene sequencing provided evidence of three groups of sequence variants.
von Loewenich
Friederike D
FD
Institute of Medical Microbiology and Hygiene, University of Freiburg, Freiburg, Germany.
Geissdörfer
Walter
W
Disqué
Claudia
C
Matten
Jens
J
Schett
Georg
G
Sakka
Samir G
SG
Bogdan
Christian
C
D000368:Aged; D000710:Anaplasmataceae / Q000235:genetics / Q000302:isolation & purification*; D000711:Anaplasmataceae Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D001853:Bone Marrow / Q000382:microbiology; D004269:DNA, Bacterial / Q000737:chemistry; D005060:Europe; D017809:Fatal Outcome; D005334:Fever / Q000382:microbiology*; D005798:Genes, Bacterial / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D017282:Tick-Borne Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S