Review: Toxicants in reproductive fluid and in vitro fertilization (IVF) outcome.
Some of the physical, chemical, dietary, occupational and environmental factors are having adverse effect on human reproduction. Increasing trend in reproductive disorders in recent years at least in part might be associated with these factors. The data available suggests less success rate of in vitro fertilization (IVF) outcome of parents exposed to some of the reproductive toxic chemicals as compared to parents who were not exposed to such chemicals. However, data are very meager and require more studies as some debatable data also exists. But existing positive findings encourage in advising that sub-fertile subjects, who are planning to go for the IVF, should reduce toxic exposure well in advance by adopting positive life style and work environment. Further, clinician ought to be aware of occupational and environmental exposure history of the participating couple.
Kumar
Sunil
S
Division of Reproductive and Cytotoxicology, National Institute of Occupational Health (ICMR), Ahmedabad 380016, India. sunilnioh@yahoo.com
Mishra
Vineet V
VV
D004781:Environmental Exposure / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000378:metabolism* / Q000633:toxicity; D004787:Environmental Pollution / Q000706:statistics & numerical data; D005260:Female; D005306:Fertilization / Q000187:drug effects*; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D008019:Life Style; D008297:Male; D012661:Semen / Q000187:drug effects / Q000378:metabolism*; D016896:Treatment Outcome
D004785:Environmental Pollutants