Colorectal cancer: current care, future innovations and economic considerations.
For those involved in colorectal cancer management, the present day is an exciting time. There is a multitude of new techniques to be considered for early detection (screening). National population screening for 60-69-year olds in England is due to start this year. Also, minimally invasive surgical techniques and multimodal pathways of care are aiding faster recovery, and there are increasing options for both adjuvant and palliative therapies. This article summarizes how colorectal cancer is currently managed in the UK and discusses the developments that are in the early stages of clinical use or on the horizon. Current management is discussed in detail in the hope that innovators reading the article may identify areas for improvement and allow comparison of new interventions with what are currently the gold standards. As changes are moving so fast, this review will probably only relate to the next 10 years at most. It does not provide a detailed reference list to support all therapies but indicates the key publications that will enable more detailed reading.
Specialist Registrar, Section of Surgery, Department of Surgery, Derby City Hospital, Uttoxeter Road, Derby DE22 3NE, UK. dmacafee@doctors.org.uk.
David A L
DA
Macafee
Elizabeth H
EH
Gemmill
John N
JN
Lund