[Spectrophotometric and HPLC evaluation of ceftazidime stability].
In this paper we followed up the stability of ceftazidime, raw material used in drug industry. Matherials and methods: We used three spectrophotometric methods based on ceftazidime property to form complexes with p-chloranilic acid (ac. p-CA), 3-methylbenzothiazolin-2-on hydrazone (MBTH) and N-(1-naphtil) etilendiamine (NEDA) and a chromatographic method (HPLC).


RESULTS
Our results revealed that the substances analyzed maintained minimum content allowable.
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Farmacie, Disciplina de Analiza Medicamentelor.
B
B
Palade
B
B
Cioroiu
Doina
D
Lazăr
Andreia
A
Corciovă
M I
MI
Lazăr
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D016227:Benzoquinones / Q000737:chemistry; D052160:Benzothiazoles / Q000737:chemistry; D002442:Ceftazidime / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D006835:Hydrazones / Q000737:chemistry; D013053:Spectrophotometry / Q000379:methods
D000900:Anti-Bacterial Agents; D016227:Benzoquinones; D052160:Benzothiazoles; D006835:Hydrazones; D002442:Ceftazidime; C002536:3-methyl-2-benzothiazolone hydrazone; C014400:chloranilic acid