Topical treatment of disseminated superficial actinic porokeratosis with hypericin-photodynamic therapy: a case report.
Hypericin is a photo-active dye originating from the St. John's wort. Two patients with disseminated superficial actinic porokeratosis (DSAP) were treated with photodynamic therapy (PDT) using topical hypericin. Although a partial response was obtained in one patient topical hypericin-PDT does not emerge as a promising treatment for DSAP.
Boiy
Annelies
A
Laboratory for Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, K.U.Leuven, Herestraat 49, 3000 Leuven, Belgium.
de Witte
Peter A M
PA
Roelandts
Rik
R
D000287:Administration, Topical; D000368:Aged; D000873:Anthracenes; D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010569:Perylene / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010778:Photochemotherapy; D017499:Porokeratosis / Q000532:radiotherapy*
D000873:Anthracenes; D000970:Antineoplastic Agents; D010569:Perylene; C004965:hypericin