Viral houseguests undertake interior redesign.
As part of their life cycle some single-stranded RNA viruses remodel host cytoplasmic membranes into specialized organelles. In this issue, Hsu et al. (2010) demonstrate how the viruses selectively co-opt host machinery to make this unique organelle, which has a lipid composition favorable to viral replication.
Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10065, USA.
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