Strategies at the interface of drug discovery and development: early optimization of the solid state phase and preclinical toxicology formulation for potential drug candidates.
Palucki
Michael
M
Basic Pharmaceutical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, Pennsylvania 19486, USA. michael_palucki@merck.com
Higgins
John D
JD
Kwong
Elizabeth
E
Templeton
Allen C
AC
D000818:Animals; D002626:Chemistry, Pharmaceutical; D003460:Crystallization; D004339:Drug Compounding; D055808:Drug Discovery / Q000379:methods*; D004353:Drug Evaluation, Preclinical; D004355:Drug Stability; D006801:Humans; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism; D010599:Pharmacokinetics; D012995:Solubility; D018675:Toxicity Tests
D004364:Pharmaceutical Preparations