Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report-.
A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.
Department of Anesthesiology and Pain Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
Jin Suk
JS
Park
Chong Wha
CW
Baek
Hyun
H
Kang
Su Man
SM
Cha
Jung Won
JW
Park
Yong Hun
YH
Jung
Young-Cheol
YC
Woo