Testing of a new disinfectant process for poultry viruses.
The chemical compound metam-sodium was tested at three concentrations for the ability to inactivate the infectivity of low-pathogenic avian influenza virus (LPAIV) and infectious bursal disease virus (IBDV), with virus-contaminated chicken litter used as the substrate. LPAIV was inactivated within 1 hr after the addition of metam-sodium independent of the concentration used. IBDV was not inactivated with the lowest amount of metam-sodium, but at higher concentrations the virus was inactivated within 1 hr after application. The results show that metam-sodium is able to penetrate chicken litter and inactivate enveloped as well as nonenveloped viruses because of its ability to form the active compound methyl isothiocyanate, which acts as a fumigant.
College of Veterinary Medicine, Department of Population Health, University of Georgia, Athens, GA, USA.
Lauren
L
Gay
Egbert
E
Mundt
D000818:Animals; D002460:Cell Line; D002642:Chick Embryo; D002645:Chickens; D004202:Disinfectants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006799:Housing, Animal; D007243:Infectious bursal disease virus / Q000187:drug effects*; D009980:Influenza A virus / Q000187:drug effects*; D010575:Pesticides / Q000494:pharmacology; D013859:Thiocarbamates / Q000494:pharmacology*
D004202:Disinfectants; D010575:Pesticides; D013859:Thiocarbamates; C008435:methyldithiocarbamate