Unsaturated beta-ketoesters as versatile electrophiles in organocatalysis.
Beta-ketoesters, which have widely been employed as nucleophiles, are also useful electrophiles in organocatalytic quinine mediated cascade reactions, leading to the formation of products bearing multiple stereocenters in high stereoselectivity.
Piovesana
Susy
S
Dipartimento di Chimica, Sapienza University of Roma and Istituto di Chimica Biomolecolare del CNR, P.le Aldo Moro 5, 00185 Roma, Italy.
Schietroma
Daniele M Scarpino
DM
Tulli
Ludovico G
LG
Monaco
Mattia R
MR
Bella
Marco
M
D002384:Catalysis; D004952:Esters; D007659:Ketones / Q000737:chemistry*; D011803:Quinine / Q000737:chemistry; D013237:Stereoisomerism
D004952:Esters; D007659:Ketones; D011803:Quinine