Challenges in using mobile phones for collection of antiretroviral therapy adherence data in a resource-limited setting.
Frequent antiretroviral therapy adherence monitoring could detect incomplete adherence before viral rebound develops and thus potentially prevent treatment failure. Mobile phone technologies make frequent, brief adherence interviews possible in resource-limited settings; however, feasibility and acceptability are unknown. Interactive voice response (IVR) and short message service (SMS) text messaging were used to collect adherence data from 19 caregivers of HIV-infected children in Uganda. IVR calls or SMS quantifying missed doses were sent in the local language once weekly for 3-4 weeks. Qualitative interviews were conducted to assess participant impressions of the technologies. Participant interest and participation rates were high; however, weekly completion rates for adherence queries were low (0-33%), most commonly due to misunderstanding of personal identification numbers. Despite near ubiquity of mobile phone technology in resource-limited settings, individual level collection of healthcare data presents challenges. Further research is needed for effective training and incentive methods.
Department of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA. jhaberer@partners.org
Jessica E
JE
Haberer
Julius
J
Kiwanuka
Denis
D
Nansera
Ira B
IB
Wilson
David R
DR
Bangsberg
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D017028:Caregivers; D040421:Cell Phone; D002648:Child; D002675:Child, Preschool; D003625:Data Collection / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D055118:Medication Adherence; D011446:Prospective Studies; D036301:Qualitative Research; D017010:Reminder Systems; D014454:Uganda