Iodine-mediated synthesis of 3H-indoles via intramolecular cyclization of enamines.
The synthesis of 3H-indoles was achieved via the iodine-mediated intramolecular cyclization of enamines. A wide variety of 3H-indole derivatives bearing multifunctional groups were obtained in good to high yields under transition metal-free reaction conditions.
Department of Chemistry, Renmin University of China, Beijing 100872, China.
Zhiheng
Z
He
Huanrong
H
Li
Zhiping
Z
Li
D000475:Alkenes / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028561:Transition Elements / Q000737:chemistry
D000475:Alkenes; D000588:Amines; D007211:Indoles; D028561:Transition Elements; D007455:Iodine