[Mistaking a long QT syndrome for epilepsy: does every seizure call for an ECG?].
Syncope is a common and difficult differential diagnosis for epilepsy. One possible cause for a cardiac syncope is a long QT syndrome (LQTS). LQTS with torsade de pointes tachycardia can lead to lethal ventricular fibrillation and cardiac arrest. Patients with LQTS when first diagnosed as suffering from epileptic fits often experience a particularly long diagnostic delay which may even take years. In some cases, the diagnosis of LQTS is not made until the patient needs resuscitation due to a cardiac arrest. Therefore, ECG recording should be performed for every patient presenting with a seizure considered to be of epileptic origin not only at the beginning of the disease but also when fits occur in spite of antiepileptic treatment in order to prevent an incorrect diagnosis and delay in making the correct diagnosis.
Klinik und Poliklinik für Neurologie, Uniklinik Köln, Kerpener Strasse 62, Köln. lothar.burghaus@uk-koeln.de
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Burghaus
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Liu
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Eggers
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Müller-Ehmsen
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Fink
D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac; D003937:Diagnosis, Differential; D004562:Electrocardiography; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis*; D006334:Heart Function Tests; D006801:Humans; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D012640:Seizures / Q000209:etiology*; D016171:Torsades de Pointes / Q000150:complications / Q000175:diagnosis; D014693:Ventricular Fibrillation / Q000175:diagnosis
D000927:Anticonvulsants