A central role for p38 MAPK in the early transcriptional response to stress.
The mitogen-activated protein kinase p38 (p38 MAPK) is activated by a number of stresses. A recent study in BMC Genomics has uncovered the early transcriptional responses to three types of stress and has demonstrated a central role for p38 MAPK in mediating these responses. See research article http://www.biomedcentral.com/1471-2164/11/144.
Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK. alan.j.whitmarsh@manchester.ac.uk
Alan J
AJ
Whitmarsh
D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D015398:Signal Transduction / Q000502:physiology*; D013312:Stress, Physiological / Q000502:physiology*; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism*
D048051:p38 Mitogen-Activated Protein Kinases