DNA-functionalised blend micelles: mix and fix polymeric hybrid nanostructures.
We report the formation and characterisation of easily functionalisable mixed micelles with DNA/PEO corona and PPO core which can be loaded with hydrophobic molecules and stabilised by the formation of a cross-linked semi-interpenetrating network. Furthermore, the corona is functionalised by hybridisation either with dye-modified complementary DNA, with demonstrable distance control, or with DNA-labelled gold nanoparticles.
Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Minseok
M
Kwak
Andrew J
AJ
Musser
Jeewon
J
Lee
Andreas
A
Herrmann
D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D053768:Metal Nanoparticles / Q000737:chemistry; D008823:Micelles; D049329:Nanostructures / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D011092:Polyethylene Glycols / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*
D008823:Micelles; D011108:Polymers; D011092:Polyethylene Glycols; D006046:Gold; D004247:DNA