Extensive comedonal and cystic acne in Patau syndrome.
Patau syndrome is a chromosomal disorder associated with multiple malformations caused by inheritance of an extra chromosome (trisomy 13). Some skin defects have been reported in patients with Patau syndrome, such as scalp defects, glabellar stains, deep palmar creases, rocker-bottom feet, convex soles, hyperconvextity of the nails, and multiple hemangiomas. To our knowledge, widespread comedonal and cystic acne have not been previously reported in Patau syndrome.
Torrelo
Antonio
A
Department of Dermatology, Hospital del Nino Jesus, Madrid, Spain. atorrelo@aedv.es
Fernandez-Crehuet
Pablo
P
Del Prado
Elena
E
Martes
Pilar
P
Hernández-Martín
Angela
A
De Diego
Verónica
V
Carapeto
Francisco
F
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000235:genetics; D000038:Abscess / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D000152:Acne Vulgaris / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D001585:Benzoyl Peroxide / Q000627:therapeutic use; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics; D002981:Clindamycin / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D005145:Face; D005260:Female; D006801:Humans; D007223:Infant; D012176:Retinoids / Q000627:therapeutic use; D012627:Sebaceous Glands / Q000002:abnormalities; D013577:Syndrome; D014314:Trisomy / Q000175:diagnosis* / Q000235:genetics
D012176:Retinoids; D002981:Clindamycin; D004917:Erythromycin; D001585:Benzoyl Peroxide