Plasma cell leukemia presenting as organizing pneumonia refractory to high-dose steroid therapy.
A case of steroid-refractory organizing pneumonia (OP) as the initial presentation of plasma cell leukemia (PCL) in a patient who had no prior exposure to chemotherapy or radiation is described. Since OP is traditionally a steroid-responsive disease, this case raises the possibility of a previously unknown patient subgroup with variable disease pattern and/or behavior in patients with plasma cell neoplasm.
Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI 48201, USA. ntageja@med.wayne.edu
Nishant
N
Tageja
Jasdeepa
J
Nagi
Jason
J
Valent
Jeffrey
J
Zonder
D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis
D005938:Glucocorticoids