Intranasal eosinophilic angiocentric fibrosis: a case report and review.
Eosinophilc angiocentric fibrosis is a rare fibrosing vasculitis of unknown etiology that is progressive and potentially disfiguring. It has a predilection for the upper airways presenting most commonly as an obstructing mass lesion that is diagnosed histologically. Thus far, it has been nonfatal in the more than 40 reported cases; however, subglottic and ocular involvement has resulted in significant morbidity in several patients. Treatment has been challenging with persistent disease in most cases. The current case is a prototypical presentation with a limited nasal septal lesion providing the opportunity to discuss clinically relevant issues and increase awareness.
Sunde
Jumin
J
The University of Alabama School of Medicine, University of Alabama at Birmingham, BDB 563, Birmingham, AL 35294, USA. jsunde@uab.edu
Alexander
Kathrina A
KA
Reddy
Vishnu V B
VV
Woodworth
Bradford A
BA
D004802:Eosinophilia / Q000150:complications / Q000473:pathology*; D005355:Fibrosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000209:etiology / Q000473:pathology / Q000601:surgery; D009300:Nasal Septum / Q000473:pathology* / Q000601:surgery; D009668:Nose Diseases / Q000473:pathology* / Q000601:surgery