Cutaneous metastasis of ovarian carcinoma with shadow cells mimicking a primary pilomatrical neoplasm.
Shadow cells are characteristic of pilomatricoma, although they have been described in other cutaneous and visceral neoplasms, particularly endometrioid adenocarcinomas of the female genital tract. We describe a metastasis of an ovarian endometrioid adenocarcinoma with shadow cells to the skin that was initially misinterpreted as a pilomatricoma. We compare the histology of the ovarian neoplasm to 21 pilomatricomas. This is the first reported case of a cutaneous metastasis of a visceral neoplasm mimicking a primary pilomatrical neoplasm.
Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, University Hospital, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
Daniel
D
Lalich
Ossama
O
Tawfik
Julia
J
Chapman
Garth
G
Fraga
D000328:Adult; D001132:Arm; D001706:Biopsy; D018269:Carcinoma, Endometrioid / Q000556:secondary*; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D010052:Ovariectomy; D010053:Ovary / Q000473:pathology; D018296:Pilomatrixoma / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000556:secondary*