Nuclear mRNA on the move.
Innovations in live-cell microscopy and single-molecule analysis have allowed a new direct view of nuclear messenger RNA dynamics. A new study extends previous analyses of mRNA-protein intranuclear transport and links this critical step to the kinetics of moving through nuclear pore complexes. Seeing nuclear mRNA on the move will impact future work on pore translocation and nuclear organization.
Noble
Kristen N
KN
Vanderbilt University School of Medicine, Department of Cell and Developmental Biology, Nashville, TN 37232-8240, USA.
Wente
Susan R
SR
D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D022022:Nuclear Pore / Q000235:genetics / Q000378:metabolism*; D021381:Protein Transport / Q000235:genetics; D034443:RNA Transport / Q000235:genetics*; D012333:RNA, Messenger / Q000378:metabolism*
D002352:Carrier Proteins; D012333:RNA, Messenger