Case Report of a 2-year-old boy with Takayasu's arteritis: an atypical, severe presentation of a rare disease.
Takayasu's arteritis is a granulomatous giant-cell arteritis of the aorta and its major branches. It primarily affects East Asian women in their second or third decade of life but is well known to affect all ethnicities across the world. Given its systemic nature, Takayasu's arteritis has multiorgan involvement, with the majority of disease morbidity related to the cardiovascular, central nervous, and renal systems. This report describes an unusual presentation of Takayasu's arteritis in a 2½-year-old boy. This is the first report in the literature describing the presence of both severe aortic regurgitation and diffuse coronary artery involvement in a patient so young.
Division of Pediatric Cardiology, Department of Pediatrics, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA. dberman@chla.usc.edu
Darren P
DP
Berman
Alan B
AB
Lewis
Grace C
GC
Kung
D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012720:Severity of Illness Index; D013625:Takayasu Arteritis / Q000175:diagnosis*