A simple primary amine thiourea catalyzed highly enantioselective conjugate addition of alpha,alpha-disubstituted aldehydes to maleimides.
School of Pharmacy, East China University of Science, Shanghai 200237, China.
Fei
F
Xue
Lu
L
Liu
Shilei
S
Zhang
Wenhu
W
Duan
Wei
W
Wang
D000447:Aldehydes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D008301:Maleimides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
D000447:Aldehydes; D000588:Amines; D008301:Maleimides; D012997:Solvents; D013890:Thiourea