Catalytic intermolecular hydroamination of vinyl ethers.
This manuscript details the development of a palladium-catalyzed hydroamination of vinyl ethers. It is proposed that palladium catalyzes the hydroamination via Bronsted base catalysis, where palladium is protonated by the relatively acidic sulfonamide to generate a palladium hydride as well as the active anionic sulfonamide nucleophile. Thus, this process is distinct from known palladium-catalyzed hydroaminations of styrene derivatives that utilize less acidic amines.
Pahadi
Nirmal K
NK
Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS, 66045-7582.
Tunge
Jon A
JA