[Spectrophotometric and HPLC evaluation of ceftazidime stability].
In this paper we followed up the stability of ceftazidime, raw material used in drug industry. Matherials and methods: We used three spectrophotometric methods based on ceftazidime property to form complexes with p-chloranilic acid (ac. p-CA), 3-methylbenzothiazolin-2-on hydrazone (MBTH) and N-(1-naphtil) etilendiamine (NEDA) and a chromatographic method (HPLC).


RESULTS
Our results revealed that the substances analyzed maintained minimum content allowable.
Palade
B
B
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Farmacie, Disciplina de Analiza Medicamentelor.
Cioroiu
B
B
Lazăr
Doina
D
Corciovă
Andreia
A
Lazăr
M I
MI
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D016227:Benzoquinones / Q000737:chemistry; D052160:Benzothiazoles / Q000737:chemistry; D002442:Ceftazidime / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D006835:Hydrazones / Q000737:chemistry; D013053:Spectrophotometry / Q000379:methods
D000900:Anti-Bacterial Agents; D016227:Benzoquinones; D052160:Benzothiazoles; D006835:Hydrazones; D002442:Ceftazidime; C002536:3-methyl-2-benzothiazolone hydrazone; C014400:chloranilic acid