Expiratory muscle training in spinal cord injury: a randomized controlled trial.
OBJECTIVE
To assess the effectiveness of expiratory muscle training on the pulmonary function of spinal cord injured patients.


METHODS
Randomized controlled trial.


METHODS
Acute inpatient rehabilitation hospital.


METHODS
Patients (N=29, 22 men and 7 women) with recent traumatic, motor complete, spinal cord injury (SCI) at or above level T1 consecutively admitted to an SCI rehabilitation service. Subjects were randomized to either resistance training (n=16) or sham training (n=13).


METHODS
The subjects completed either sham training or expiratory muscle resistive training with maximal expiratory force using a small handheld device, which is a tube with an aperture at the distal end, for 10 repetitions twice a day 5 days a week for a total of 6 weeks.


METHODS
Pulmonary function tests were measured before and after the training program and included forced vital capacity (FVC); forced expiratory volume in 1 second (FEV1); maximum expiratory pressure (MEP), which is often referred to as forced expiratory pressure; maximum inspiratory pressure (MIP), which is often referred to as negative inspiratory force; inspiratory capacity (IC); expiratory reserve volume (ERV); total lung capacity (TLC); functional residual capacity (FRC); and residual volume (RV).


RESULTS
FVC, FEV1, and ERV improved in both groups. Although exit values of MEP were improved in both groups compared with entry values, this increase was statistically significant only in the resistance training group. No significant improvements occurred in IC, TLC, FRC, or RV from entry to exit. MIP improved in both groups, but this increase was statistically significant only in the resistance training group. There was also a significant between-group difference in MEP exit values (98cmH(2)O for the resistance training group and 59cmH(2)O for the sham training group, t=3.45, P=.002). Multivariate analyses failed to reveal significant effects of treatment for any of the pulmonary function tests.


CONCLUSIONS
The resistance training group had significantly greater exit MEP values than the sham training group in univariate analysis only. However, improvements in pulmonary function were noted in both the resistance training and sham training groups. Although multivariate analysis failed to reveal a significant difference between groups, these findings offer some indication that expiratory training may benefit people with SCI.
Roth
Elliot J
EJ
Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. EJR@northwestern.edu
Stenson
Katherine W
KW
Powley
Scott
S
Oken
Jeffrey
J
Primack
Scott
S
Nussbaum
Steven B
SB
Berkowitz
Michael
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001945:Breathing Exercises; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055070:Resistance Training / Q000379:methods*; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000503:physiopathology / Q000534:rehabilitation*; D016896:Treatment Outcome