[Dedifferentiated chondrosarcoma: radiologic-pathologic correlation].
Dedifferentiated chondrosarcomas are highly malignant tumors characterized by conventional low-grade chondrosarcoma with abrupt transition to foci that have dedifferentiated into a higher-grade noncartilaginous more aggressive sarcoma. The dedifferentiated component, an osteosarcoma or fibrosarcoma, determines the prognosis. Its identification is key for management. A diagnosis of dedifferentiated chondrosarcoma should be suggested by the presence of "tumoral dimorphism" with cartilaginous component and aggressive lytic component invading adjacent soft tissues.
Service de Radiologie B, Hôpital Cochin, 27, faubourg Saint-Jacques, 750014 Paris. Guillaume.bierry@chru-strasbourg.fr
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G
Bierry
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Feydy
F
F
Larousserie
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E
Pluot
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H
Guerini
R
R
Campagna
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C
Dufau-Andreu
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P
Anract
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A
Babinet
J L
JL
Dietemann
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Chevrot
J L
JL
Drapé
D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002356:Cartilage / Q000000981:diagnostic imaging / Q000473:pathology; D054337:Cell Dedifferentiation; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D005354:Fibrosarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010014:Osteolysis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D012516:Osteosarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D011379:Prognosis; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed