Synthesis, characterization and antimicrobial properties of a Co(II)-phthalylsulfathiazolate complex.
The reaction between phthalylsulfathiazole (H(2)PST), in alkaline aqueous solution, and cobalt(II) nitrate led to a pink solid, [Co(PST)(H(2)O)(4)] (1), which was characterized by elemental and thermogravimetric analysis; FT-IR, Raman and diffuse reflectance spectra. Spectroscopic data reveal that the ligand would be doubly deprotonated and that the Co(II) ion environment is a distorted octahedral one. (1) showed antibacterial activity similar to the ligand.
Monti
Laura
L
Química Inorgánica, Universidad Nacional de Rosario, Suipacha 531, 2000, Rosario, Argentina.
Pontoriero
Ana
A
Mosconi
Natalia
N
Giulidori
Cecilia
C
Hure
Estela
E
Williams
Patricia A M
PA
Rodríguez
María Victoria
MV
Feresin
Gabriela
G
Campagnoli
Darío
D
Rizzotto
Marcela
M
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003035:Cobalt / Q000737:chemistry*; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009152:Mutagenicity Tests; D019697:Onions / Q000187:drug effects / Q000235:genetics; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D056831:Coordination Complexes; D003035:Cobalt; C025913:cobaltous nitrate