[Renal involvement in Behcet's disease].
BACKGROUND
Renal involvement in the Behcet's disease is rare. The clinical features vary from urinary sediment's abnormalities to ESRD.


OBJECTIVE
We propose to study the clinical, biological and histological data, the therapeutic management and the prognosis of patients.


METHODS
We report a retrospective study including 8 patients representing 1.23 % of cases.


RESULTS
The average age of the patient was of 37 +/- 12. 35 years with a clear male prevalence. Urinary signs were discovered fortuitously by the strips in the majority of the cases after an average of 18 months. It's about proteinuria and hematuria. Renal insufficiency and hypertension were rare. Pathological study highlighted 3 cases of amyloidosis, 2 cases of IgA nephropathy, 1 case of minimal change disease, 1 case of endo and extracapillary glomerulonephritis and 1 case of interstitial nephropathy. Patients having GN were treated by corticoids and immunosuppressive agents and those having an interstitial nephropathy were treated symptomatically with good evolution in the majority of the cases. Only one patient is dead, he had amyloidosis. Prognosis depended on the precocity of the diagnosis, the histological type and the treatment.


CONCLUSIONS
The renal involvement during Behçet's disease is rare. Amyloidosis and Ig A nephropathy are the most frequent. Treatment is still controversial.
Service de Médecine interne A - Hôpital Charles Nicolle de Tunis.
Mondher
M
Ounissi
Khaoula
K
Ben Abdelghani
Taher
T
Gargueh
Sami
S
Turki
Rym
R
Goucha
Ezzedine
E
Abderrahim
Fathi
F
Ben Hamida
Hedi
H
Ben Maiz
Adel
A
Khedher
D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult