Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!
Delayed haemorrhage due to vitamin K deficiency in early infancy has rarely been the cause of acquired hemostatic disorders. We report here 11 cases of vitamin K deficiency bleeding (VKDB), despite receiving appropriate dosage of injectible vitamin K at birth. Bleeding symptoms ranged from excessive bleed from cuts to intracranial bleed. Tuberculosis, diarrhea with intermittent antibiotic therapy were some of the associated symptoms. Laboratory tests confirmed acquired bleeding diathesis due to vitamin K deficiency, which was corrected after adequate vitamin K supplementation. VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis.
National Institute of Immunohaematology, KEM Hospital, Parel, Mumbai, India.
Priyanka
P
Kasatkar
Shrimati
S
Shetty
Kanjaksha
K
Ghosh
D003967:Diarrhea / Q000209:etiology; D006801:Humans; D007223:Infant; D012189:Retrospective Studies; D014376:Tuberculosis / Q000209:etiology; D014812:Vitamin K / Q000627:therapeutic use; D014813:Vitamin K Deficiency / Q000150:complications*; D006475:Vitamin K Deficiency Bleeding / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
D014812:Vitamin K