BF2-chelated tetraarylazadipyrromethenes as NIR fluorochromes.
The synthesis and properties of a new visible red/near-infrared fluorochrome for bioconjugation via activated ester groups is described. Representative amine conjugations with amino acid lysine and proteins lysozyme and trypsin were successfully accomplished.
Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Mariusz
M
Tasior
Donal F
DF
O'Shea
D001372:Aza Compounds / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry*; D002614:Chelating Agents / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008239:Lysine / Q000737:chemistry; D015394:Molecular Structure; D009113:Muramidase / Q000737:chemistry / Q000378:metabolism; D011162:Porphobilinogen / Q000031:analogs & derivatives* / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared; D013237:Stereoisomerism; D014357:Trypsin / Q000737:chemistry
D001372:Aza Compounds; D001896:Boron Compounds; D002614:Chelating Agents; D005456:Fluorescent Dyes; C507544:dipyrromethene; D011162:Porphobilinogen; D009113:Muramidase; D014357:Trypsin; D008239:Lysine