Psychosis alters association between IQ and future risk of attempted suicide: cohort study of 1,109,475 Swedish men.
OBJECTIVE
To explore associations between IQ measured in early adulthood and subsequent hospital admissions for attempted suicide and to explore the role of psychosis and examine associations of IQ with specific methods of attempted suicide.


METHODS
Cohort study.


METHODS
Sweden.


METHODS
1 109 475 Swedish men with IQ measured in early adulthood followed up for an average 24 years.


METHODS
Hospital admission for attempted suicide.


RESULTS
17 736 (1.6%) men had at least one hospital admission for attempted suicide by any means during follow-up. After adjustment for age and socioeconomic status, lower IQ scores were associated with an elevated risk of attempted suicide by any means (hazard ratio per standard deviation decrease in IQ=1.57, 95% confidence interval 1.54 to 1.60), with stepwise increases in risk across the full IQ range (P for trend<0.001). Similar associations were observed for all specific methods of attempted suicide. Separate analyses indicated that associations between IQ and attempted suicide were restricted to participants without psychosis and that IQ had no marked impact on risk of attempted suicide in those with psychosis.


CONCLUSIONS
Low IQ scores in early adulthood were associated with a subsequently increased risk of attempted suicide in men free from psychosis. A greater understanding of the mechanisms underlying these associations may provide opportunities and strategies for prevention.
Batty
G David
GD
Medical Research Council Social and Public Health Sciences Unit, University of Glasgow, Glasgow.
Whitley
Elise
E
Deary
Ian J
IJ
Gale
Catharine R
CR
Tynelius
Per
P
Rasmussen
Finn
F
D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000523:psychology; D015331:Cohort Studies; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007360:Intelligence; D008297:Male; D011618:Psychotic Disorders / Q000150:complications* / Q000453:epidemiology; D018570:Risk Assessment; D012907:Smoking / Q000523:psychology; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data; D013548:Sweden / Q000453:epidemiology; D055815:Young Adult