[Dedifferentiated chondrosarcoma: radiologic-pathologic correlation].
Dedifferentiated chondrosarcomas are highly malignant tumors characterized by conventional low-grade chondrosarcoma with abrupt transition to foci that have dedifferentiated into a higher-grade noncartilaginous more aggressive sarcoma. The dedifferentiated component, an osteosarcoma or fibrosarcoma, determines the prognosis. Its identification is key for management. A diagnosis of dedifferentiated chondrosarcoma should be suggested by the presence of "tumoral dimorphism" with cartilaginous component and aggressive lytic component invading adjacent soft tissues.
Bierry
G
G
Service de Radiologie B, Hôpital Cochin, 27, faubourg Saint-Jacques, 750014 Paris. Guillaume.bierry@chru-strasbourg.fr
Feydy
A
A
Larousserie
F
F
Pluot
E
E
Guerini
H
H
Campagna
R
R
Dufau-Andreu
C
C
Anract
P
P
Babinet
A
A
Dietemann
J L
JL
Chevrot
A
A
Drapé
J L
JL
D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002356:Cartilage / Q000000981:diagnostic imaging / Q000473:pathology; D054337:Cell Dedifferentiation; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D005354:Fibrosarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010014:Osteolysis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D012516:Osteosarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D011379:Prognosis; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed