N-H activation of amines and ammonia by Ru via metal-ligand cooperation.
A nonoxidative addition pathway for the activation of NH bonds of ammonia and amines by a Ru(II) complex is reported. The pincer complex 1 cleaves N-H bonds via metal-ligand cooperation involving aromatization of the pincer ligand without a change in the formal oxidation state of the metal. Electron-rich N-H bond substrates lead to reversible activation, while electron-poor substrates result in stable activation products. Isotopic labeling studies using ND(3) as well as density functional theory calculations were used to shed light on the N-H activation mechanism.
Khaskin
Eugene
E
Department of Organic Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
Iron
Mark A
MA
Shimon
Linda J W
LJ
Zhang
Jing
J
Milstein
David
D