Drying gels.
There are several reasons why it may be desirable to dry a gel after its use for electrophoresis. Firstly, it is a convenient way of storing the end result of the experiment. Secondly, drying a gel that is fragile may make it easier to handle (say, during optical scanning). Thirdly, and most importantly, it may be necessary to dry a gel to allow the most efficient detection of radioactive samples on it by autoradiography or fluorography. The method described below is rapid and generally applicable to all types of slab gel, although the description below applies specifically to a thin (0.5-1 mm thick) polyacrylamide (15%) gel being prepared for fluorography (see Chapter 17 ).
Institute of Cancer Research, Royal Cancer Hospital, Chester Beatty Laboratories, London, England.
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Smith