Antifungal Activity of Eugenol against Penicillium, Aspergillus, and Fusarium Species.
The antifungal activity of eugenol in a model system against aspergilli (Aspergillus niger, Aspergillus terreus, and Emericella nidulans), penicilli (Penicillium expansum, Penicillium glabrum, and Penicillium italicum), and fusaria (Fusarium oxysporum and Fusarium avenaceum) was investigated. Minimum detection time (time to attain a colony diameter of 1 cm) and the kinetic parameters were evaluated. The effectiveness of the active compound seemed to be strain or genus dependent; 100 mg/liter represented a critical value for P. expansum, P. glabrum, P. italicum, A. niger, and E. nidulans because a further increase of eugenol resulted in fungistatic activity. The radial growth of A. terreus and F. avenaceum was inhibited at 140 mg/liter, and growth of F. oxysporum was completely inhibited at 150 mg/liter.
Campaniello
Daniela
D
Department of Food Science, Faculty of Agricultural Science, University of Foggia, Via Napoli 25, 71100 Foggia, Italy.
Corbo
Maria Rosaria
MR
Sinigaglia
Milena
M
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects*; D015169:Colony Count, Microbial; D004305:Dose-Response Relationship, Drug; D005054:Eugenol / Q000494:pharmacology*; D005516:Food Microbiology; D005670:Fusarium / Q000187:drug effects*; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D010407:Penicillium / Q000187:drug effects*; D013997:Time Factors
D000935:Antifungal Agents; D005054:Eugenol