The Scandinavian Solutions for Wellness study - a two-arm observational study on the effectiveness of lifestyle intervention on subjective well-being and weight among persons with psychiatric disorders.
BACKGROUND
Solutions for Wellness (SfW) is an educational 3-month program concerning nutrition and exercise for persons with psychiatric disorders on psychotropic medication, who have weight problems. This observational study assessed the impact of SfW on subjective well-being, weight and waist circumference (WC).


METHODS
Data was collected at 49 psychiatric clinics. Where the SfW program was offered patients could enter the intervention group; where not, the control group. Subjective well-being was measured by the Subjective Well-being under Neuroleptics scale (SWN), at baseline, at the end of SfW participation, and at a follow-up 6 months after baseline. Demographic, disease and treatment data was also collected.


RESULTS
314 patients enrolled in the SfW group, 59 in the control group. 54% of the patients had schizophrenia, 67% received atypical antipsychotics, 56% were female. They averaged 41 +/- 12.06 years and had a BMI of 31.4 +/- 6.35. There were significant differences at baseline between groups for weight, SWN total score and other factors. Stepwise logistic models controlling for baseline covariates yielded an adjusted non-significant association between SfW program participation and response in subjective well-being (SWN increase). However, statistically significant associations were found between program participation and weight-response (weight loss or gain < 1 kg) OR = 2; 95% CI [1.1; 3.7] and between program participation and WC-response (WC decrease or increase < 2 cm) OR = 5; 95% CI [2.4; 10.3]), at 3 months after baseline.


CONCLUSIONS
SfW program participation was associated with maintaining or decreasing weight and WC but not with improved subjective well-being as measured with the SWN scale.
Porsdal
Vibeke
V
Eli Lilly Danmark A/S, Nybrovej 110, DK - 2800 Lyngby, Denmark. porsdal@lilly.com
Beal
Catherine
C
Kleivenes
Ole Kristian
OK
Martinsen
Egil W
EW
Lindström
Eva
E
Nilsson
Harriet
H
Svanborg
Pär
P
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001835:Body Weight; D003625:Data Collection; D005260:Female; D006266:Health Education / Q000379:methods* / Q000458:organization & administration; D006304:Health Status; D006801:Humans; D008019:Life Style; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000523:psychology; D009765:Obesity / Q000139:chemically induced / Q000628:therapy*; D017063:Outcome Assessment, Health Care; D015397:Program Evaluation; D012537:Scandinavian and Nordic Countries; D012559:Schizophrenia / Q000188:drug therapy; D011795:Surveys and Questionnaires; D055105:Waist Circumference; D015430:Weight Gain / Q000187:drug effects; D015431:Weight Loss / Q000187:drug effects
D014150:Antipsychotic Agents