Successful treatment of late Salmonella infections in total hip replacement - report of two cases.
BACKGROUND
Salmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture.


METHODS
Two patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Salmonella Enteridis infection with an abscess in the groin, with loosening of both components. He underwent a successful one stage cemented revision hip replacement, followed by 6 weeks of antibiotic therapy (ciprofloxacin). He had no recurrence or complications. The second patient was admitted in a septic condition with ARDS to the Intensive Care Unit 7 years following an uncemented total hip replacement. From an ultrasound guided hip aspirate Salmonella cholerae-suis was isolated. He underwent a successful a two-stage revision hip replacement.


CONCLUSIONS
Successful treatment of such potentially life threatening infections is achievable using modern orthopaedic techniques and close collaboration with the infectious diseases specialists.
Department of Orthopaedics, University of Szeged, 6 Semmelweis Street, Szeged 6720, Hungary. tothk@szote.u-szeged.hu
Kálmán
K
Tóth
Gábor
G
Janositz
Gyula
G
Kovács
Krisztián
K
Sisák
Ervin
E
Rudner
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip; D002939:Ciprofloxacin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D012476:Salmonella arizonae / Q000302:isolation & purification*; D012477:Salmonella enteritidis / Q000302:isolation & purification*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin