Pigmented poroid neoplasm mimicking nodular melanoma.
We reported the case of a 92-year-old woman with a pigmented and non-pigmented surface of the pedunculated nodule on her lower leg. Microscopic examination revealed that this nodule consisted of a component of small, dark, homogenous, poroid cells and cuticular cells in the dermis. The histopathological features of the lesion were consistent with poroid neoplasm. Immunohistochemistry showed that HMB-45 and Melan-A were positive in malanocytes and melanophages of the pigmented areas. Unlike most poroid neoplasms, this case showed pigmented lesion mimicked nodular melanoma.
Department of Dermatology, Nippon Medical School, Bunkyou-ku, Tokyo, Japan.
Tsuyoshi
T
Mitsuishi
Shin-ichi
S
Ansai
Takashi
T
Ueno
Seiji
S
Kawana
D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis*; D057091:Poroma / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*