Lymphocytic colitis under treatment with duloxetine.
Lymphocytic colitis is a disease characterised by chronic watery diarrhoea that can only be diagnosed histologically, since colonoscopy reveals macroscopically normal mucosa. A causal relationship to the administration of certain drugs has repeatedly been described. In this report we describe a case of lymphocytic colitis that developed after initiation of treatment with duloxetine - a selective serotonin- and noradrenaline-reuptake inhibitor - and remitted after discontinuation of the drug. Since a causal relationship between the onset of lymphocytic colitis and the use of duloxetine is highly probable, duloxetine should be included among those drugs capable of inducing lymphocytic colitis.
Kusnik
B
B
Pathology, Klinikum Kulmbach, Germany.
Stolte
M
M
D000369:Aged, 80 and over; D046730:Colitis, Lymphocytic / Q000139:chemically induced* / Q000175:diagnosis* / Q000517:prevention & control; D000068736:Duloxetine Hydrochloride; D005260:Female; D006801:Humans; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects; D013876:Thiophenes / Q000009:adverse effects*
D000068736:Duloxetine Hydrochloride; D017367:Selective Serotonin Reuptake Inhibitors; D013876:Thiophenes