Synthesis of annonacin isolated from Annona densicoma.
A total synthesis of annonacin (1) was accomplished by using versatile chiral building block 2 for synthesizing the mono-tetrahydrofuran (THF) annonaceous acetogenins.
Oasa
Mayu
M
Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University, Nagano, Japan.
Hattori
Yasunao
Y
Konno
Hiroyuki
H
Makabe
Hidefumi
H
D054378:Acetogenins / Q000737:chemistry; D031041:Annona / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
D054378:Acetogenins; D005663:Furans; D007783:Lactones; C018674:tetrahydrofuran; C053442:annonacin