[Acute myocardial infarction in young smokers treated by coronary angioplasty. In-hospital prognosis and long-term outcome in a consecutive series of 93 patients].
OBJECTIVE
The study evaluated in-hospital and long-term outcome of patients less than 50 years old with myocardial infarction within 12 hours after symptom onset treated by coronary angioplasty.


METHODS
This is a retrospective study with survival analysis by Kaplan-Meier method in patients included from December 2003 to February 2008.


RESULTS
We included 93 patients aged 42,8+/-5,2 years old with smoking estimated at 27,7+/-12,7 pack-years. Thirty-one patients (33,3%) were dyslipidemic and 36 patients had family history of coronary artery disease. Thirty patients (32,3%) had an anterior myocardial infarction and four patients (4.4%) had Killip greater than 2. Coronary angioplasty was performed within 4.5+/-3.0 hours after symptom onset with TIMI 3 final flow in the culprit vessel in 96.8%. One patient died from cardiogenic shock. With a follow-up of 85 patients during 20.0+/-15.6 months, the survival without death was 98.2% and survival without major cardiac complication was 87.9% at 24 months. Seventy-two patients (85.7%) were taking a betablocker, 81 patients (96.4%) aspirin, 75 patients (89.3%) a statin and 64 patients (76.2%) an angiotensin-converting inhibitor. Only 50 patients (58.8%) were nonsmokers.


CONCLUSIONS
Thus, young smokers with acute MI treated by coronary angioplasty have a good prognosis during in-hospital stay and long-term outcome. Secondary medical treatment prevention is well followed but there is a low rate of smoking cessation.
Service de cardiologie, centre hospitalier Emile-Muller, 20, rue du Docteur Laennec, Mulhouse, France. jacqueminl@ch-mulhouse.fr
Jacquemin
J
L
Bourrelly
B
N
Roth
R
O
Wiedemann
W
J-Y
Le Bouar
le B
R
Levy
L
J
Monassier
M
J-P
D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies; D012907:Smoking; D013997:Time Factors; D016896:Treatment Outcome