Xenohormesis: health benefits from an eon of plant stress response evolution.
Xenohormesis is a biological principle that explains how environmentally stressed plants produce bioactive compounds that can confer stress resistance and survival benefits to animals that consume them. Animals can piggyback off products of plants' sophisticated stress response which has evolved as a result of their stationary lifestyle. Factors eliciting the plant stress response can judiciously be employed to maximize yield of health-promoting plant compounds. The xenohormetic plant compounds can, when ingested, improve longevity and fitness by activating the animal's cellular stress response and can be applied in drug discovery, drug production, and nutritional enhancement of diet.
Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Denver, School of Medicine, Aurora, CO, USA. phoopermd@gmail.com
Philip L
PL
Hooper
Paul L
PL
Hooper
Michael
M
Tytell
Lászlo
L
Vígh
D000818:Animals; D001688:Biological Products / Q000737:chemistry / Q000378:metabolism; D020834:Ethnopharmacology; D006360:Heat-Shock Proteins / Q000378:metabolism; D008136:Longevity; D010944:Plants / Q000378:metabolism*; D013312:Stress, Physiological
D001688:Biological Products; D006360:Heat-Shock Proteins