Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells.
Tinghuai
T
Wu
Jane
J
Tian
Roy G
RG
Cutler
Richard S
RS
Telljohann
David A
DA
Bernlohr
Mark P
MP
Mattson
James T
JT
Handa
D053299:Apolipoprotein B-100 / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism*; D050556:Fatty Acid-Binding Proteins / Q000172:deficiency / Q000235:genetics*; D055786:Gene Knockout Techniques; D006801:Humans; D008055:Lipids / Q000502:physiology; D012333:RNA, Messenger / Q000235:genetics*; D034741:RNA, Small Interfering / Q000494:pharmacology*; D055213:Retinal Pigment Epithelium / Q000502:physiology*; D014280:Triglycerides / Q000096:biosynthesis / Q000378:metabolism*
D053299:Apolipoprotein B-100; C493412:FABP5 protein, human; D050556:Fatty Acid-Binding Proteins; D008055:Lipids; D012333:RNA, Messenger; D034741:RNA, Small Interfering; D014280:Triglycerides; D002784:Cholesterol