Successful treatment of late Salmonella infections in total hip replacement - report of two cases.
BACKGROUND
Salmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture.


METHODS
Two patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Salmonella Enteridis infection with an abscess in the groin, with loosening of both components. He underwent a successful one stage cemented revision hip replacement, followed by 6 weeks of antibiotic therapy (ciprofloxacin). He had no recurrence or complications. The second patient was admitted in a septic condition with ARDS to the Intensive Care Unit 7 years following an uncemented total hip replacement. From an ultrasound guided hip aspirate Salmonella cholerae-suis was isolated. He underwent a successful a two-stage revision hip replacement.


CONCLUSIONS
Successful treatment of such potentially life threatening infections is achievable using modern orthopaedic techniques and close collaboration with the infectious diseases specialists.
Tóth
Kálmán
K
Department of Orthopaedics, University of Szeged, 6 Semmelweis Street, Szeged 6720, Hungary. tothk@szote.u-szeged.hu
Janositz
Gábor
G
Kovács
Gyula
G
Sisák
Krisztián
K
Rudner
Ervin
E
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip; D002939:Ciprofloxacin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D012476:Salmonella arizonae / Q000302:isolation & purification*; D012477:Salmonella enteritidis / Q000302:isolation & purification*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin