Enhancement of glucose transport by selected plant foods in muscle cell line L6.
Glucose uptake activity of 11 plant foods was assessed in L6 myotubes. Among them onion and ginger showed potent enhancement of glucose transport. This effect required new protein synthesis of glucose transporters. In addition, onion-induced glucose uptake in L6 myotubes was mediated through activation of phosphoinositide 3-kinase.
Drug Delivery System Excellence Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla 90110, Thailand. kusumarn.n@psu.ac.th
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Noipha
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Ratanachaiyavong
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Ninla-Aesong
D031021:Anacardium / Q000737:chemistry; D000818:Animals; D031601:Azadirachta / Q000737:chemistry; D001692:Biological Transport / Q000187:drug effects*; D002460:Cell Line; D028041:Centella / Q000737:chemistry; D028526:Coriandrum / Q000737:chemistry; D019662:Cucurbitaceae / Q000737:chemistry; D003847:Deoxyglucose / Q000378:metabolism; D005737:Garlic / Q000737:chemistry; D020939:Zingiber officinale / Q000737:chemistry; D005947:Glucose / Q000378:metabolism*; D018485:Muscle Fibers, Skeletal / Q000187:drug effects* / Q000378:metabolism*; D019697:Onions / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D051381:Rats
D010936:Plant Extracts; D003847:Deoxyglucose; D005947:Glucose