Determinants of gestational diabetes mellitus: A case control study in a district tertiary care hospital in south India.
OBJECTIVE
To study the determinants of Gestational Diabetes Mellitus (GDM).


METHODS
Case-control study.


METHODS
Sri Avittom Thirunal Hospital, Thiruvananthapuram district, Kerala, South India.


METHODS
300 GDM women as cases and 300 age-matched controls.


METHODS
Sociodemographic characteristics, pre-pregnancy Body Mass Index (BMI), menstrual history, obstetric history, infertility history, family history of diabetes in first degree relatives, recurrent urinary tract infection (UTI), and moniliasis.


METHODS
T-test, Fishers Exact Test, Chi square test, Adjusted Odds Ratio with 95% CI.


RESULTS
Pre-pregnancy BMI >/= 25 (P < 0.001, OR = 2.7), irregular menstrual cycle (P = 0.006), treatment for infertility (P = 0.001, OR = 3.3), family history of diabetes (P = 0.001, OR = 4.5), history of diabetes in mother (P = 0.003), previous pregnancy losses (P = 0.04), past GDM (P = 0.035), prematurity (P = 0.01), pre-eclampsia (P = 0.04), polyhydramnios (P < 0.001, OR = 6.0), UTI (P < 0.001, OR = 3.2), and moniliasis (P < 0.001, OR = 7.6) were significantly associated with present GDM.


CONCLUSIONS
Early identification of women at risk of GDM and prompt treatment is recommended to prevent complications.
Department of Obstetrics and Gynecology, Sree Chitra Tirunal Institute for Medical Sciences, Thiruvananthapuram, India.
Mamta
M
Bhat
Ramesha
R
K N
Sankara P
SP
Sarma
Sangeetha
S
Menon
Sowmini
S
C V
Ganesh Kumar
GK
S