A membranous spindle matrix orchestrates cell division.
Eukaryotic cell division uses morphologically different forms of mitosis, referred to as open, partially open and closed mitosis, for accurate chromosome segregation and proper partitioning of other cellular components such as endomembranes and cell fate determinants. Recent studies suggest that the spindle matrix provides a conserved strategy to coordinate the segregation of genetic material and the partitioning of the rest of the cellular contents in all three forms of mitosis.
Department of Embryology, Carnegie Institute for Science, Baltimore, Maryland 21218, USA. zheng@ciwemb.edu
Yixian
Y
Zheng
D000818:Animals; D002455:Cell Division / Q000235:genetics / Q000502:physiology*; D020090:Chromosome Segregation / Q000235:genetics / Q000502:physiology; D006801:Humans; D008870:Microtubules / Q000235:genetics / Q000378:metabolism; D008954:Models, Biological; D008941:Spindle Apparatus / Q000235:genetics / Q000378:metabolism*