Intranasal eosinophilic angiocentric fibrosis: a case report and review.
Eosinophilc angiocentric fibrosis is a rare fibrosing vasculitis of unknown etiology that is progressive and potentially disfiguring. It has a predilection for the upper airways presenting most commonly as an obstructing mass lesion that is diagnosed histologically. Thus far, it has been nonfatal in the more than 40 reported cases; however, subglottic and ocular involvement has resulted in significant morbidity in several patients. Treatment has been challenging with persistent disease in most cases. The current case is a prototypical presentation with a limited nasal septal lesion providing the opportunity to discuss clinically relevant issues and increase awareness.
The University of Alabama School of Medicine, University of Alabama at Birmingham, BDB 563, Birmingham, AL 35294, USA. jsunde@uab.edu
Jumin
J
Sunde
Kathrina A
KA
Alexander
Vishnu V B
VV
Reddy
Bradford A
BA
Woodworth
D004802:Eosinophilia / Q000150:complications / Q000473:pathology*; D005355:Fibrosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000209:etiology / Q000473:pathology / Q000601:surgery; D009300:Nasal Septum / Q000473:pathology* / Q000601:surgery; D009668:Nose Diseases / Q000473:pathology* / Q000601:surgery