TransFind--predicting transcriptional regulators for gene sets.
The analysis of putative transcription factor binding sites in promoter regions of coregulated genes allows to infer the transcription factors that underlie observed changes in gene expression. While such analyses constitute a central component of the in-silico characterization of transcriptional regulatory networks, there is still a lack of simple-to-use web servers able to combine state-of-the-art prediction methods with phylogenetic analysis and appropriate multiple testing corrected statistics, which returns the results within a short time. Having these aims in mind we developed TransFind, which is freely available at http://transfind.sys-bio.net/.
Kiełbasa
Szymon M
SM
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D-14195 Berlin, Germany. kielbasa@molgen.mpg.de
Klein
Holger
H
Roider
Helge G
HG
Vingron
Martin
M
Blüthgen
Nils
N
D001665:Binding Sites; D005786:Gene Expression Regulation; D020407:Internet; D010802:Phylogeny; D011401:Promoter Regions, Genetic; D012984:Software; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic
D014157:Transcription Factors