Catalytic asymmetric transacetalization.
A catalytic enantioselective transacetalization has been developed. The chiral phosphoric acid TRIP was demonstrated to be an efficient and highly enantioselective catalyst for the activation of O,O-acetals. The reaction enables the asymmetric synthesis of acetals with the acetal carbon as the only stereogenic center.
Corić
Ilija
I
Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470, Mülheim an der Ruhr, Germany.
Vellalath
Sreekumar
S
List
Benjamin
B
D000080:Acetals / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D008968:Molecular Conformation; D013237:Stereoisomerism; D013379:Substrate Specificity
D000080:Acetals