[Zerebrale Amyloidangiopathie : Cerebral amyloid angiopathy].
Cerebral amyloid angiopathy (CAA) is defined by the accumulation of β-amyloid in the walls of cortical arteries. The risk factors of CAA include advanced age and the presence of certain alleles of apolipoprotein E. CAA mostly remains asymptomatic, but the classical manifestation is intracerebral hemorrhage. A definite diagnosis can only be made on the basis of histopathological examination. Detection of lobar hemorrhages and lobar microhemorrhages in imaging investigations support the diagnosis of CAA as long as other causes can be excluded.
Neurologische Klinik HELIOS-Kliniken Schwerin, Schwerin, Deutschland. frank.block@helios-kliniken.de
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D016657:Cerebral Amyloid Angiopathy / Q000150:complications* / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans