Virulence of Escherichia coli B2 isolates from meat and animals in a murine model of ascending urinary tract infection (UTI): evidence that UTI is a zoonosis.
In vivo evidence of a connection between urinary tract infections (UTI) and foods is lacking. The virulence of 13 Escherichia coli B2 isolates from healthy animals and fresh meat was investigated in a murine model of ascending UTI. All isolates produced positive bladder cultures (10(2) to 10(7) CFU), and nine isolates produced positive kidney cultures (10(2) to 10(5) CFU).
National Center for Antimicrobials and Infection Control, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S, Denmark. lja@ssi.dk
Lotte
L
Jakobsen
Anette M
AM
Hammerum
Niels
N
Frimodt-Møller
D000818:Animals; D002645:Chickens / Q000382:microbiology*; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000302:isolation & purification* / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology* / Q000473:pathology; D005260:Female; D007668:Kidney / Q000382:microbiology; D008460:Meat / Q000382:microbiology*; D051379:Mice; D013552:Swine / Q000382:microbiology*; D001743:Urinary Bladder / Q000382:microbiology; D014552:Urinary Tract Infections / Q000382:microbiology* / Q000473:pathology; D014774:Virulence