[The sleep organization in the Krushinskii-Molodkina strain rats after sleep deprivation and different intensity audiogenic seizures].
Organization of sleep after different intensity audiogenic paroxysmal seizures evoked in animals under normal diurnal wakefulness-sleep cycle and after 12-hour fast-wave sleep deprivations or 6-hour total sleep deprivation was studied in Krushinskii-Molodkina strain rats with an inherited predisposition to audiogenic convulsions. Under all specified conditions, intensive audiogenic clonic or clonic-tonic convulsions caused long-lasting and pronounced sleep disorders in rats associated with disorganization of the mechanisms of starting the fast-wave sleep phase in the first place. But after experimental deprivations of sleep the audiogenic paroxysmal seizures run only as initial motor excitement without obvious convulsions. Such sort of seizures promote a faster beginning of recovery process after deprivations and did not cause any disorganization of the function of the brain systems responsible for starting and shaping (maintenance) fast-wave sleep.
S I
SI
Vataev
G A
GA
Oganesian
D000818:Animals; D020195:Epilepsy, Reflex / Q000150:complications / Q000503:physiopathology*; D051381:Rats; D012892:Sleep Deprivation / Q000209:etiology / Q000503:physiopathology*; D012895:Sleep, REM