Eight-year survival after advanced gastric cancer treated with S-1 followed by surgery.
We report a case of advanced gastric cancer, with cervical, axillary, and abdominal paraaortic lymph node metastases, that was successfully treated with chemotherapy and surgery. The disease was initially considered unresectable, and the patient was treated with orally administered S-1. Chemotherapy was effective, and all lymph node metastases disappeared after 6 courses. After 27 mo of chemotherapy, the patient underwent curative surgery, with subtotal gastrectomy and lymph node dissection. Histopathological examination revealed many viable poorly differentiated adenocarcinoma cells in the stomach, but no cancer cells in the lymph nodes. The patient is alive, without recurrence, 8 years later. This, therefore, is a case report of an 8-year survivor of advanced gastric cancer with distant lymph node metastasis.
Department of Medical Oncology, Cancer Institute Hospital of JFCR, 3-8-31 Ariake Koto-ku, Tokyo 135-8550, Japan.
Susumu
S
Hijioka
Keisho
K
Chin
Yasuyuki
Y
Seto
Noriko
N
Yamamoto
Kiyohiko
K
Hatake
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D018572:Disease-Free Survival; D004338:Drug Combinations; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid