The effect of tiotropium bromide on health-related quality of life in chronic obstructive pulmonary disease.
Tiotropium bromide is a once-daily anticholinergic recommended for maintenance treatment of chronic obstructive pulmonary disease. The 24-h bronchodilation in patients with chronic obstructive pulmonary disease achieved with tiotropium treatment is currently unique. However, there is an increasing demand for proven efficacy in parameters of more direct interest to patients, in addition to physiological parameters. This article reviews the data currently available on the efficacy of tiotropium to improve the health-related quality of life of patients with chronic obstructive pulmonary disease.
University of Aberdeen, Department of General Practice and Primary Care, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, Scotland, UK. d.price@abdn.ac.uk.
David
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Price