[Atypical carcinoid of the lung with abnormal elevation of serum ProGRP level; report of a case].
We report a rare case of an atypical carcinoid of the lung with the elevation of serum ProGRP. A 79-year-old female was referred to our hospital presenting with an abnormal shadow by a chest X-ray film. Chest computed tomography (CT) scan revealed a well-defined solitary nodule in the left lower lobe. The serum level of ProGRP was elevated to 2.267 pg/ml (normal range: <46 pg/ml). Pulmonary carcinoid was pathologically suggested by a transbronchial lung biopsy. Considering the patient's general condition, a partial wide resection was performed. Pathological diagnosis was atypical carcinoid. After the operation, further increase of the serum ProGRP level was noted, and multiple liver metastases developed.
Department of Thoracic Surgery, Toda Chuo General Hospital, Toda, Japan.
Tetsushi
T
Ito
Kyeongil
K
Kim
Masahiro
M
Taira
Masao
M
Kinoshita
Norihiko
N
Ikeda
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D002276:Carcinoid Tumor / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis*; D010446:Peptide Fragments / Q000097:blood*; D011994:Recombinant Proteins / Q000097:blood
D014408:Biomarkers, Tumor; D010446:Peptide Fragments; D011994:Recombinant Proteins; C087079:pro-gastrin-releasing peptide (31-98)