[A cutaneous thickening case...].
The authors present a clinical case of a 79 years old female patient, with a progressive cutaneous thickening of the face, trunk and limbs, lasting for 6 years. She also presented exertional dyspnea and intermittent solid dysphagia. The laboratory study identified IgG KAPA monoclonal protein and antinuclear antibodies with a speckled pattern. The nailfold capillaroscopy was normal. A detailed physical examination together with cutaneous histopathology led to the diagnosis of Scleromyxedema, a rare cutaneous scleroderma like disease. The differential diagnosis of cutaneous sclerosis is discussed.
Serviço de Reumatologia, Hospitais da Universidade de Coimbra, Coimbra. saramserra@hotmail.com
S
S
Serra
C
C
Ambrósio
M
M
João Salvador
J
J
Silva
D
D
Serra
J
J
Pedro Reis
A
A
Malcata
D000368:Aged; D005260:Female; D006801:Humans; D053718:Scleromyxedema / Q000473:pathology*; D012867:Skin / Q000473:pathology