A case report: femoral fracture in a multiple sclerosis patient with vitamin d deficiency--a preventable injury.
In this report, we describe the management of a multiple sclerosis patient with a femoral fracture who had severe vitamin D deficiency. After the patient's preoperative laboratory studies revealed a normal platelet count, the orthopedic surgeon performed an intramedullary rod fixation on the patient's left femoral fracture. After the surgery, the diagnosis of vitamin D deficiency was made by measuring the circulating serum concentration of 25-dihydroxyvita-min D (25(OH)D) via Disorin's Vitamin D immunochemiluminometric assay LIASION by LabCorp (Laboratory Corporation of America). The patient's postoperative management included the oral administration of 4000 IU of vitamin D3 in a gel-cap suspension that resulted in an elevation of the blood serum concentration of 25(OH)D to an optimal concentration of >80 nmol/L (32 ng/ml).
Biomedical Engineering and Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA. richardedlichmd@gmail.com
Richard F
RF
Edlich
Shelley S
SS
Mason
Jill S
JS
Reddig
K
K
Gubler
William B
WB
Long
D000368:Aged; D001858:Bone Nails; D002112:Calcifediol / Q000097:blood; D002762:Cholecalciferol / Q000008:administration & dosage; D005264:Femoral Fractures / Q000150:complications* / Q000517:prevention & control / Q000601:surgery; D005594:Fracture Fixation, Intramedullary; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000097:blood / Q000150:complications*; D011182:Postoperative Care; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications* / Q000188:drug therapy
D002762:Cholecalciferol; D002112:Calcifediol