Bacille Calmette-Guérin osteomyelitis of the proximal femur.
All newborns in Hong Kong are given bacille Calmette-Guérin vaccinations. Reported complications include formation of regional and extra-regional localised abscesses, osteomyelitis, and lymphadenitis. Several cases of bacille Calmette-Guérin osteomyelitis have been reported in Europe, but there are few reports of this in Asia. To the author's knowledge, this is the first case report of bacille Calmette-Guérin osteomyelitis in Hong Kong. Bacille Calmette-Guérin osteomyelitis, although rare, should be kept in mind as a potential complication of bacille Calmette-Guérin vaccination. Clinical suspicion, early diagnosis using an image-guided tissue biopsy and polymerase chain reaction study, and early commencement of chemotherapy are key to the effective management of this problem.
Chan
P K
PK
Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Shatin, Hong Kong. lewis@graduate.hku.hk
Ng
Bobby K W
BK
Wong
C Y
CY
D001500:BCG Vaccine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005269:Femur; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000209:etiology*; D016133:Polymerase Chain Reaction
D001500:BCG Vaccine