Total synthesis of (+/-)-elegansidiol, (+/-)-farnesiferol B, and (+/-)-farnesiferol D.
The racemic total synthesis of elegansidiol, farnesiferol B, and farnesiferol D has been obtained following a Diels-Alder approach. Gillman addition, cross metathesis reaction are the other key steps involved in the target synthesis.
Yadav
Jhillu Singh
JS
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Council of Scientific and Industrial Research, Hyderabad, India. yadavpub@iict.res.in
Satyanarayana
Kamani
K
Sreedhar
Pamu
P
Srihari
Pabbaraja
P
Shaik
Thokhir Basha
TB
Kalivendi
Shasi Vardhan
SV
D001688:Biological Products / Q000138:chemical synthesis* / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D009447:Neuroblastoma / Q000473:pathology; D012717:Sesquiterpenes / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis* / Q000494:pharmacology
D001688:Biological Products; D012717:Sesquiterpenes; D013729:Terpenes; C551829:elegansidiol; C551831:farnesiferol D; C551830:farnesiferol B