Prevalence of enterotoxins among Escherichia coli isolates causing bacteraemia.
The most frequent cause of bacteraemia among Gram-negative bacteria is Escherichia coli. Analysis of the genes encoding the Shigella enterotoxin 1 (ShET-1), ShET-2, enteroaggregative heat stable toxin 1 (EAST-1) toxins and AggR factor in E. coli strains causing bacteraemia revealed that set1 genes were presented significantly more frequently among quinolone-susceptible strains (P<0.0001), in phylogenetic group B2 (P=0.0004) and in biofilm strains (P=0.02). In contrast, sen genes were significantly more frequent among nalidixic acid-resistant isolates (15% vs. 6%, P=0.046) and in phylogenetic group B1 (P=0.0001). This is the first study in which ShET1, ShET2 and EAST-1 have been found in E. coli collected from blood.
Department of Microbiology and Clinical Microbiology, Adnan Menderes University, Aydin, Turkey.
Murat
M
Telli
Elisabet
E
Guiral
Jose A
JA
Martínez
Manuel
M
Almela
Jordi
J
Bosch
Jordi
J
Vila
Sara M
SM
Soto
D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000382:microbiology*; D004269:DNA, Bacterial / Q000235:genetics; D004768:Enterotoxins / Q000235:genetics*; D004926:Escherichia coli / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D037521:Virulence Factors / Q000235:genetics*
D004269:DNA, Bacterial; D004768:Enterotoxins; D029968:Escherichia coli Proteins; D037521:Virulence Factors