Unlikeliness of Pd-free gold(I)-catalyzed Sonogashira coupling reactions.
The Sonogashira coupling reaction is not catalyzed by AuI/dppe in the absence of Pd complexes. However, addition of 0.1 mol % of Pd(0) led to efficient cross-coupling reactions. The most plausible catalytic cycles for the Au-catalyzed cross-coupling reactions have been examined and are unlikely in the absence of Pd contamination.
Institute of Chemical Research of Catalonia (ICIQ), 43007 Tarragona, Spain.
Thorsten
T
Lauterbach
Madeleine
M
Livendahl
Antonio
A
Rosellón
Pablo
P
Espinet
Antonio M
AM
Echavarren
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D010165:Palladium; D006046:Gold