[The role of the connective tissue in healing process in myocardial infarction].
Myocardial infarction is followed by the inflammatory response of mezenchymal tissue leading to the debridement of the necrotic area as well as to initiation of repair followed by scar formation. The healing is a complex sequence of events consisted of four overlapping phases. Repair of the heart is under control of local and systemic regulatory factors. The knowledge of the mechanism of myocardial infarction allows to develop new strategies aimed at minimizing necrotic area and optimizing cardiac repair. This approach gives a chance to reduce the complications of myocardial infarction and to improve the quality of patients life.
Drobnik
Jacek
J
Zakład Patofizjologii, Katedra Patofizjologii, Uniwersytet Medyczny, Łódź. drob@bg.am.lodz.pl
Ciosek
Joanna
J
Jakubowski
Lucjusz
L
D000818:Animals; D049109:Cell Proliferation; D003238:Connective Tissue / Q000378:metabolism*; D006801:Humans; D008648:Mesoderm / Q000378:metabolism / Q000473:pathology; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology*; D009205:Myocarditis / Q000473:pathology / Q000503:physiopathology; D009206:Myocardium / Q000473:pathology; D009336:Necrosis / Q000517:prevention & control; D014945:Wound Healing / Q000502:physiology*