Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is a major regulator of muscle mass during growth but not for adult myofiber hypertrophy.
Shavlakadze
Thea
T
School of Anatomy and Human Biology, The University of Western Australia, Perth.
Grounds
Miranda D
MD
D000328:Adult; D006801:Humans; D006984:Hypertrophy / Q000473:pathology / Q000503:physiopathology; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D040542:Mechanotransduction, Cellular; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000473:pathology* / Q000503:physiopathology*; D009929:Organ Size; D005082:Physical Exertion
D007334:Insulin-Like Growth Factor I