Differential substrate specificity of two inositol transporters of Bacillus subtilis.
Bacillus subtilis IolT is the major myo-inositol transporter for growth, while IolF is a minor one unable to support growth. We found that either IolT or IolF was sufficient for moderate growth using D-chiro-inositol. Conversely to IolT, IolF transported D-chiro-inositol more preferentially than myo-inositol. These results indicate that IolT and IolF are different in substrate specificity.
Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe, Japan.
Tetsuro
T
Morinaga
Takatsugu
T
Matsuse
Hitoshi
H
Ashida
Ken-ichi
K
Yoshida
D001412:Bacillus subtilis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D001692:Biological Transport; D007294:Inositol / Q000737:chemistry / Q000378:metabolism*; D009004:Monosaccharide Transport Proteins / Q000378:metabolism*; D013379:Substrate Specificity
D001426:Bacterial Proteins; D009004:Monosaccharide Transport Proteins; D007294:Inositol