Imide-catalyzed oxidation system: sulfides to sulfoxides and sulfones.
A new combination system, the oxidation of sulfides using aqueous NaOCl in the presence of a catalytic amount of imide under two-phase conditions, has been developed. The combination effectively converts various sulfides to the corresponding sulfoxides and sulfones. It was deduced that the imide could react with NaOCl to produce N-chloroimide, which would play roles of both the active oxidizing reagent and phase transfer catalyst.
Chemical Development Laboratories, CMC Center, Takeda Pharmaceutical Company Limited, Yodogawa-ku, Osaka 532-8686, Japan.
Naohiro
N
Fukuda
Tomomi
T
Ikemoto
D002384:Catalysis; D007094:Imides / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013440:Sulfides / Q000737:chemistry*; D013454:Sulfoxides / Q000737:chemistry*
D007094:Imides; D007202:Indicators and Reagents; D013440:Sulfides; D013454:Sulfoxides