Hemorrhagic, bullous Henoch Schonlein purpura in a 16-year-old girl with previously undiagnosed dominant dystrophic epidermolysis bullosa.
A 16-year-old girl presenting with systemic and cutaneous symptoms of hemorrhagic Henoch-Schonlein purpura continued to develop bullae on top of old scars. Past history was significant for bullae on the feet and legs after trauma. Based on history, physical examination, disease course, and biopsy, the patient, her mother, and other family members were diagnosed with dominant dystrophic epidermolysis bullosa, explaining the severe course and complications of her Henoch-Schonlein purpura.
Department of Dermatology, University of Cincinnati, Cincinnati, Ohio 45229-3039, USA.
Farah
F
Abdulla
Anita P
AP
Sheth
Anne W
AW
Lucky
D000293:Adolescent; D001768:Blister / Q000175:diagnosis / Q000235:genetics; D016108:Epidermolysis Bullosa Dystrophica / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D007070:Immunoglobulin A / Q000032:analysis; D011241:Prednisone / Q000627:therapeutic use
D007070:Immunoglobulin A; D011241:Prednisone