Hypertensive disorders of pregnancy: preventative-, immediate- and long-term management.
The hypertensive disorders of pregnancy are common and continue to be significant contributors to maternal and perinatal mortality and morbidity, both globally and in the UK. This review aims to describe the recent developments in the understanding of the pathophysiology of the disease processes, potential strategies for identification of women at high risk, and current and future therapeutic strategies for the treatment and prevention of hypertension in pregnancy. Women who experience adverse pregnancy outcomes are also at increased risk of premature cardiovascular disease, and potential therapeutic strategies to minimize their risk profile are discussed.
Nelson
Scott M
SM
Clinician Scientist, University of Glasgow, Reproductive and Maternal Medicine, and Division of Developmental Medicine, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 ER, UK. s.nelson@clinmed.gla.ac.uk.
Greer
Ian A
IA