Sirolimus oral ulcer with Cedecea davisae superinfection.
Cedecea davisae is a member of the Enterobacteriaceae family and is an uncommon pathogen. This organism has been isolated from the blood, sputum, and cutaneous ulcers of only a handful of patients, most of these being elderly or otherwise medically compromised. This is a report of a patient, status post renal transplantation, who developed an oral ulcer associated with sirolimus use and superinfected with C. davisae. According to the literature, this is the first case of C. davisae detected in the oral cavity. Antibiotic therapy led to prompt resolution of this very large ulcer.
Harvard School of Dental Medicine, Department of Oral Medicine, Infection and Immunity, Boston, Massachusetts, USA. hmawardi@partners.org
H
H
Mawardi
M
M
Pavlakis
D
D
Mandelbrot
S-B
SB
Woo
D000328:Adult; D000368:Aged; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D019226:Oral Ulcer / Q000139:chemically induced* / Q000209:etiology; D020123:Sirolimus / Q000009:adverse effects*; D015163:Superinfection / Q000188:drug therapy / Q000209:etiology*
D007166:Immunosuppressive Agents; D020123:Sirolimus