Comparison of the armed/disarmed building blocks of the D-gluco and D-glucosamino series in the context of chemoselective oligosaccharide synthesis.
A very elegant Fraser-Reid armed-disarmed approach recently expanded to the building blocks of the superarmed and superdisarmed series shows very high utility in chemoselective oligosaccharide synthesis. Although a number of studies dedicated to the chemoselective activation of 2-amino-2-deoxysugars have emerged, little remains known about how the reactivity of the armed/disarmed building blocks of the neutral sugars directly compares to that of their 2-aminosugar counterparts. A preliminary study of this comparative reactivity is presented.
Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
Teerada
T
Kamkhachorn
Archana R
AR
Parameswar
Alexei V
AV
Demchenko
D002236:Carbohydrate Conformation; D005944:Glucosamine / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D009844:Oligosaccharides; D005944:Glucosamine