Haematological effects of minimized compared to conventional extracorporeal circulation after coronary revascularization procedures.
During the last decade, minimized extracorporeal circulation (MECC) systems have shown beneficial effects to the patients over the conventional cardiopulmonary bypass (CECC) circuits. This is a prospective randomized study of 99 patients who underwent coronary artery bypass grafting (CABG) surgery, evaluating the postoperative haematological effects of these systems. Less haemodilution (p=0.001) and markedly less haemolysis (p<0.001), as well as better preservation of the coagulation system integrity (p=0.01), favouring the MECC group, was found. As a clinical result, less bank blood requirements were noted and a quicker recovery, as far as mechanical ventilation support and ICU stay are concerned, was evident with the use of MECC systems. As a conclusion, minimized extracorporeal circulation systems may attenuate the adverse effects of conventional circuits on the haematological profile of patients undergoing CABG surgery.
Department of Cardiothoracic Surgery, AHEPA University Hospital, Thessaloniki, Greece.
Kyriakos
K
Anastasiadis
Christos
C
Asteriou
Apostolos
A
Deliopoulos
Helena
H
Argiriadou
Georgios
G
Karapanagiotidis
Polychronis
P
Antonitsis
Vasilios
V
Grosomanidis
Georgios
G
Misias
Christos
C
Papakonstantinou
D000368:Aged; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods*; D005112:Extracorporeal Circulation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006403:Hematologic Tests / Q000379:methods; D006438:Hemodilution / Q000379:methods; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D016896:Treatment Outcome