Switching off FRET by analyte-induced decomposition of squaraine energy acceptor: A concept to transform 'turn off' chemodosimeter into ratiometric sensors.
FRET cassette-type sensors, SN-1 and SN-2, which contain two naphthalimide donors and a squaraine acceptor, have been developed on the concept of switching off FRET through removing the spectral overlap by the analyte-induced decompositions of acceptor chromophore. SN-2 shows sensitive responses to fluoride anion and cyanide through both naked-eye detectable colour changes and ratiometric fluorescence changes. As the first example, SN-2 confirms that transformation of the common 'turn-off' chemodosimeter into ratiometric sensors can be realized conveniently based on the novel 'switching FRET off' approach.
Yu
Haibo
H
Stake Key Laboratory of Fine Chemicals, Dalian University of Technology, Zhongshan Road 158, Dalian 116012, China.
Fu
Meiyan
M
Xiao
Yi
Y
D000838:Anions; D003486:Cyanides / Q000032:analysis / Q000737:chemistry; D003503:Cyclobutanes / Q000737:chemistry*; D005453:Fluorescence; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D005459:Fluorides / Q000032:analysis / Q000737:chemistry; D008956:Models, Chemical; D053644:Naphthalimides / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*
D000838:Anions; D003486:Cyanides; D003503:Cyclobutanes; D005456:Fluorescent Dyes; D053644:Naphthalimides; D010636:Phenols; C480596:squaraine; D005459:Fluorides