When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome.
A report in this issue of Molecular Cell (Dechassa et al., 2010) provides evidence that a translocating SWI/SNF-nucleosome complex efficiently displaces neighboring nucleosomes in vitro and may account for SWI/SNF-dependent nucleosome eviction in vivo.
Liu
Ning
N
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA.
Hayes
Jeffrey J
JJ