[Atypical carcinoid of the lung with abnormal elevation of serum ProGRP level; report of a case].
We report a rare case of an atypical carcinoid of the lung with the elevation of serum ProGRP. A 79-year-old female was referred to our hospital presenting with an abnormal shadow by a chest X-ray film. Chest computed tomography (CT) scan revealed a well-defined solitary nodule in the left lower lobe. The serum level of ProGRP was elevated to 2.267 pg/ml (normal range: <46 pg/ml). Pulmonary carcinoid was pathologically suggested by a transbronchial lung biopsy. Considering the patient's general condition, a partial wide resection was performed. Pathological diagnosis was atypical carcinoid. After the operation, further increase of the serum ProGRP level was noted, and multiple liver metastases developed.
Ito
Tetsushi
T
Department of Thoracic Surgery, Toda Chuo General Hospital, Toda, Japan.
Kim
Kyeongil
K
Taira
Masahiro
M
Kinoshita
Masao
M
Ikeda
Norihiko
N
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D002276:Carcinoid Tumor / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis*; D010446:Peptide Fragments / Q000097:blood*; D011994:Recombinant Proteins / Q000097:blood
D014408:Biomarkers, Tumor; D010446:Peptide Fragments; D011994:Recombinant Proteins; C087079:pro-gastrin-releasing peptide (31-98)