Absence of the septum pellucidum associated with a midline fornical nodule and ventriculomegaly: a report of two cases.
We report two autopsy cases that revealed the partial absence of the septum pellucidum with ventriculomegaly. In each case, the brain showed mild dilatation of both frontal horns of the lateral ventricles, normal third and fourth ventricles and no aqueductal stenosis. The posterior portion of the septum pellucidum was absent and the fornices were fused in a single midline nodule, abnormally displaced to a caudal position and lodged in the foramina of Monro. The brain base showed no apparent abnormalities; the optic nerves were well developed. We conclude that the caudally displaced fornix in the absence of the septum pellucidum may have intermittently obstructed the foramina of Monro and induced mild ventriculomegaly.
Department of Pathology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. ykcmd@naver.com
Yi Kyeong
YK
Chun
Hye Sun
HS
Kim
Sung Ran
SR
Hong
Je G
JG
Chi
D000028:Abortion, Induced; D000328:Adult; D002552:Cerebral Ventricles / Q000002:abnormalities*; D003616:Dandy-Walker Syndrome / Q000000981:diagnostic imaging / Q000473:pathology; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D020712:Fornix, Brain / Q000002:abnormalities*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D012688:Septum Pellucidum / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D016216:Ultrasonography, Prenatal