Salvage of pelvic recurrence of colorectal cancer.
Although the incidence of locally recurrent colorectal cancer has been reduced by improved surgical techniques and the frequent use of multimodality therapy, pelvic recurrence remains a significant problem. Radiation or chemotherapy may provide palliation but it is often short-lived. For fit candidates without evidence of extrapelvic disease, surgical resection (anterior resection, abdominoperineal resection, pelvic exenteration, or abdominosacral resection) may be the most appropriate treatment. For patients with unresectable disease, isolated pelvic perfusion may provide effective palliation.
Varker
Kimberly A
KA
Division of Surgical Oncology, Comprehensive Cancer Center, The Ohio State University Medical Center, Columbus, Ohio, USA.
Wanebo
Harold J
HJ
D010478:Chemotherapy, Cancer, Regional Perfusion; D015179:Colorectal Neoplasms / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010385:Pelvic Exenteration; D010388:Pelvis / Q000601:surgery; D012445:Sacrococcygeal Region / Q000601:surgery