Pineal anlage tumor in a 5-month-old boy.
Pineal tumors are rare neoplasms that are categorized into pineoblastomas, pineocytomas, and pineal parenchymal tumors of intermediate differentiation. Pineal anlage tumors are primary pineal tumors with neuroepithelial and ectomesenchymal differentiation and without endodermal differentiation. The authors review the literature and report the case of a 5-month-old boy with a pineal anlage tumor. This is only the sixth case of a pineal anlage tumor reported in the English-language literature adding to the understanding of this tumor's presentation, immunomorphological and molecular characteristics, embryological origin, radiological appearance, treatment outcome, and prognosis.
Department of Neurosurgery, Loma Linda University Medical Center, Loma Linda, California 92354, USA.
Joffre E
JE
Olaya
Ravi
R
Raghavan
Laura
L
Totaro
Alexander
A
Zouros
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003399:Craniotomy; D003937:Diagnosis, Differential; D004630:Emergencies; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D017600:Neuroectodermal Tumor, Melanotic / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D044583:Neuroendoscopy; D009460:Neurologic Examination; D010870:Pineal Gland / Q000473:pathology / Q000601:surgery; D010871:Pinealoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014696:Ventriculostomy
D014408:Biomarkers, Tumor