Direct Pd-catalyzed benzylation of highly electron-deficient perfluoroarenes.
An efficient and practical method to a wide range of perfluorinated unsymmetrical diarylmethanes with good to excellent yields and high regioselectivities has been developed by Pd-catalyzed direct benzylation of highly electron-deficient perfluoroarenes; excellent compatibility of functional groups has also been established.
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
Shilu
S
Fan
Chun-Yang
CY
He
Xingang
X
Zhang
D002384:Catalysis; D004583:Electrons; D005461:Fluorine / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D005461:Fluorine; D010165:Palladium