[The temperature regulation of the spontaneous activity frequency and the concomitant changes of the cortical neurons' spike amplitude].
In the sensorimotor cortical slices of guinea pigs, the rate of neurons' spike activity increased at 27-29 and 34-36 degrees C. The change of the firing rate was accompanied by a drop in the spike amplitude at the temperature below 27 and above 34 degrees C. Usually after cooling to 24 degrees C the spike amplitude fully restored when the temperature increased to 32-34 degrees C. The fall of spike amplitude at t >35 degrees C could not be stopped by temperatyre decrease. The data obtained indicate the important role of the neuron membrane K+ permeability.
N V
NV
Pasikova
Iu S
IuS
Mednikova
I V
IV
Averina
D000818:Animals; D002463:Cell Membrane Permeability / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D006168:Guinea Pigs; D006358:Hot Temperature; D009474:Neurons / Q000502:physiology*; D011188:Potassium / Q000378:metabolism
D011188:Potassium