[Role of prognostic factors in evaluation of survival in breast cancer].
The aim of our study is to evaluate the prognostic value of tumor size, regional lymph nodes and steroid-hormones receptors status, histological grade, and the presence of metastasis in other organs.


METHODS
Our retro-prospective study analyzes a group of 266 patients diagnosed and treated for breast cancer in the IVth Obstetrics and Gynecology Clinic.


RESULTS
150 of the patients (56.7%) presented stage I disease, and only 39 (14.7%) stage IV. 151 (57%) of the patients had no regional lymph nodes metastasis and 252 (94.9%) were free of metastatic disease when they first presented for diagnosis. Almost 43% of all tumors were poorly differentiated. In the majority of cases, the tumors were positive for steroid receptors. The survival rate after 5 years was higher in the absence of lymph nodes metastasis (76%) and the presence of a low Nottingham prognostic index (78%).


CONCLUSIONS
The identification and evaluation of prognostic factors is an essential step for treatment planning and limiting metastatic disease.
Popârlan
T
T
Universitatea de Medicină şi Farmacie Gr. T. Popa laşi Facultatea de Medicină, Clinica a IV(-a) Obstetrică Ginecologie.
Muscă
Simona
S
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D001943:Breast Neoplasms / Q000737:chemistry / Q000401:mortality* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000737:chemistry / Q000401:mortality* / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D011987:Receptors, Steroid / Q000032:analysis; D012383:Romania / Q000453:epidemiology; D015996:Survival Rate; D042461:Vascular Endothelial Growth Factor A / Q000032:analysis
D014408:Biomarkers, Tumor; D011987:Receptors, Steroid; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A