MiRror: a combinatorial analysis web tool for ensembles of microRNAs and their targets.
CONCLUSIONS
The miRror application provides insights on microRNA (miRNA) regulation. It is based on the notion of a combinatorial regulation by an ensemble of miRNAs or genes. miRror integrates predictions from a dozen of miRNA resources that are based on complementary algorithms into a unified statistical framework. For miRNAs set as input, the online tool provides a ranked list of targets, based on set of resources selected by the user, according to their significance of being coordinately regulated. Symmetrically, a set of genes can be used as input to suggest a set of miRNAs. The user can restrict the analysis for the preferred tissue or cell line. miRror is suitable for analyzing results from miRNAs profiling, proteomics and gene expression arrays.


BACKGROUND
http://www.proto.cs.huji.ac.il/mirror
Department of Biological Chemistry, Sudarsky Center for Computational Biology and School of Computer Science and Engineering, Hebrew University of Jerusalem, Israel.
Yitzhak
Y
Friedman
Guy
G
Naamati
Michal
M
Linial
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods; D005786:Gene Expression Regulation; D020407:Internet; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism
D035683:MicroRNAs