Time varying neonatal seizure localization.
BACKGROUND
A common cause for damage to the neonatal brain is a shortage in the oxygen supply to the brain or asphyxia. Neonatal seizures are the most frequent manifestation of neonatal neurologic disorders. Multichannel EEG recordings allow topographic localization of seizure foci.


OBJECTIVE
We want to objectively determine the spatial distribution of the seizure on the scalp, the location in time and order the dominant sources in the brain based on their strength.


METHODS
In this paper we combine a method based on higher order CP-decomposition with subsequent singular value decomposition (SVD).


RESULTS
We illustrate the abilities of the method on simulated as well as on real neonatal seizure EEG.


CONCLUSIONS
The proposed method provides reliable time and spatial information about the seizure, gives a clear overview of what is going on in the EEG and allows easy interpretation.
Department of Electrical Engineering (ESAT), Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, Postbox 02446, 3001 Leuven-Heverlee, Belgium. wouter.deburchgraeve@esat.kuleuven.be
W
W
Deburchgraeve
P J
PJ
Cherian
M
M
De Vos
R M
RM
Swarte
J H
JH
Blok
G H
GH
Visser
P
P
Govaert
S
S
Van Huffel
D000465:Algorithms; D001238:Asphyxia Neonatorum / Q000150:complications; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D008959:Models, Neurological; D012640:Seizures / Q000145:classification* / Q000175:diagnosis / Q000209:etiology; D012815:Signal Processing, Computer-Assisted