Alemtuzumab pretreatment and tacrolimus monotherapy in living-donor liver and kidney transplantation.
We previously described the use of alemtuzumab as a pretreatment agent in 207 living-donor renal transplants, a trial that represented the largest series to date of live-donor renal and liver transplant recipients undergoing alemtuzumab pretreatment, and confirmed the short-term safety, efficacy and cost-effectiveness of this approach. This paper examines the use of the immunosuppressive combination of alemtuzumab and tacrolimus monotherapy in 47 patients with right-lobe adult living-donor liver transplantation.
Tan
Henkie P
HP
Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. tanhp@upmc.edu.
Shapiro
Ron
R
Tom
Kusum
K
Thai
Ngoc
N
Marsh
Wallis
W
Basu
Amit
A
Marcos
Amadeo
A