A fast and highly efficient protocol for synthesis of pyrrolo[2,3-d]isoxazoles and a new series of novel benzyl bis-pyrrolo[2,3-d]isoxazoles using task-specific ionic liquids as catalyst and green solvent.
We report a mild, fast, highly efficient and eco-friendly protocol for the green synthesis of pyrrolo[2,3-d]isoxazoles and a new series of novel benzyl bis-pyrrolo[2,3-d]isoxazoles from nitro styrylisoxazoles in SnCl(2)-ionic liquid by reductive cyclization. These reactions were performed at ambient temperature which resulted in good yields in short reaction time, without requiring any organic solvent and catalyst.
Department of Chemistry, Kakatiya University. eligeti_rajan@yahoo.co.in
Eligeti
E
Rajanarendar
Samala
S
Raju
Atthunuri
A
Siva Rami Reddy
Kundur
K
Govardhan Reddy
Modugu
M
Nagi Reddy
D002384:Catalysis; D055772:Green Chemistry Technology / Q000191:economics / Q000379:methods*; D052578:Ionic Liquids / Q000737:chemistry*; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
D052578:Ionic Liquids; D007555:Isoxazoles; D011758:Pyrroles