An effective preparation of sulfonyl- or sulfinyl-substituted fluorinated alkenes and their stereoselective addition-elimination reactions with organocuprates.
Treatment of trifluorovinyl- or pentafluoropropen-1-yl sulfone or sulfoxide, which are easily prepared from commercially available 1,2-dibromofluoroalkanes, with various organocuprates affords substitution or beta-reduction products in good to excellent yields through an addition-elimination reaction sequence.
Yamada
Shigeyuki
S
Department of Chemistry and Materials Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
Shimoji
Kanoko
K
Takahashi
Toshio
T
Konno
Tsutomu
T
Ishihara
Takashi
T