Electromagnetic fields: mechanism, cell signaling, other bioprocesses, toxicity, radicals, antioxidants and beneficial effects.
Electromagnetic fields (EMFs) played a role in the initiation of living systems, as well as subsequent evolution. The more recent literature on electrochemistry is documented, as well as magnetism. The large numbers of reports on interaction with living systems and the consequences are presented. An important aspect is involvement with cell signaling and resultant effects in which numerous signaling pathways participate. Much research has been devoted to the influence of man-made EMFs, e.g., from cell phones and electrical lines, on human health. The degree of seriousness is unresolved at present. The relationship of EMFs to reactive oxygen species (ROS) and oxidative stress (OS) is discussed. There is evidence that indicates a relationship involving EMFs, ROS, and OS with toxic effects. Various articles deal with the beneficial aspects of antioxidants (AOs) in countering the harmful influence from ROS-OS associated with EMFs. EMFs are useful in medicine, as indicated by healing bone fractures. Beneficial effects are recorded from electrical treatment of patients with Parkinson's disease, depression, and cancer.
Department of Chemistry, San Diego State University, San Diego, California, USA. pkovacic@sundown.sdsu.edu
Peter
P
Kovacic
Ratnasamy
R
Somanathan
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D040421:Cell Phone; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005609:Free Radicals / Q000378:metabolism*; D006801:Humans; D015398:Signal Transduction; D014945:Wound Healing
D000975:Antioxidants; D005609:Free Radicals