[Intramuscular myxoma of intercostal muscle; report of a case].
A 72-year-old woman was reffered to our hospital for further examination of a tumor shadow in the left upper lung field which was detected in a mass screening chest X-ray. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a chest wall tumor located in the left 4th intercostal space. The lesion was suspected to be neurogenic tumor and CT-guided needle biopsy was performed. The tumor was consisted of spindle-shaped cells, but immunohistochemistry demonstrated no evidence of neurogenic tumor. As a possibility of malignant tumor could not denied, we performed tumor resection under video-assisted surgery. The lesion was not originated from nerves, but adhered to the intercostal muscle. Histologically, the tumor was consisted of spidle-shaped cells without atypia which sparsely proliferate in the myxoid stroma adjacent to intercostal muscle. In immunohistochemistry, tumor cells were positive for vimentin, and negative for desmin, S-100 protein, smooth muscle actin, CD34 and factor VIII. It was diagnosed as intramuscular myxoma. This histology in the intercostal muscle is extremely rare.
Department of Surgery, Fukuyama City Hospital, Fukuyama, Japan.
Takashi
T
Yoshioka
Masahiko
M
Muro
Kenjiro
K
Kumano
Tetsumasa
T
Yamashita
Youhei
Y
Kurose
Shinichirou
S
Kubo
Hiroki
H
Nojima
Kanyu
K
Nakano
Shinya
S
Asami
Hiroshi
H
Sasaki
Hitoshi
H
Idani
Hitoshi
H
Kin
Norihisa
N
Takakura
D000368:Aged; D005260:Female; D006801:Humans; D007366:Intercostal Muscles; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000473:pathology*; D009232:Myxoma / Q000175:diagnosis / Q000473:pathology*