Stereodifferentiation in fluorescence quenching within cholic acid aggregates.
Two cholic acid (ChA) analogues, containing a 4-nitrobenzo-2-oxa-1,3-diazole (NBD) moiety at C-3, were incorporated into ChA aggregates and submitted to fluorescence quenching by the two enantiomers of several tryptophan derivatives. In all cases, a significant stereodifferentiation was observed; the most remarkable effect was found when comparing the 3alpha and the 3beta diastereomers.
Cuquerella
M Consuelo
MC
Instituto de Tecnología Química (UPV-CSIC), Universidad Politécnica de Valencia, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n. 46022, Valencia, Spain.
Rohacova
Jana
J
Marin
M Luisa
ML
Miranda
Miguel A
MA
D019826:Cholic Acid / Q000737:chemistry*; D010069:Oxadiazoles / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism; D013816:Thermodynamics; D014364:Tryptophan / Q000737:chemistry
D010069:Oxadiazoles; C011514:4-nitrobenzofurazan; D014364:Tryptophan; D019826:Cholic Acid