Rheumatologic sequelae and challenges in organ transplantation.
Despite the increasing success of transplantation, graft recipients experience a high burden of musculoskeletal symptoms that may hinder quality of life. Post-transplant musculoskeletal problems may result from sequelae of the organ dysfunction that indicated the transplant or from the subsequent anti-rejection therapy. Rheumatology consultants need to be familiar with the spectrum of musculoskeletal syndromes presenting in these unique patients and their appropriate treatment in the context of complex drug regimens and immunosuppression.
Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, Portland Veterans Affairs Medical Center, 3181 SW Sam Jackson Park Road, Portland OR 97239, USA. schwabp@ohsu.edu
Pascale
P
Schwab
Sarah
S
Lipton
Gail S
GS
Kerr
D001168:Arthritis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006073:Gout / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006086:Graft vs Host Disease / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D009140:Musculoskeletal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D016377:Organ Transplantation / Q000009:adverse effects*; D010020:Osteonecrosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D010024:Osteoporosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D011183:Postoperative Complications; D011788:Quality of Life; D014657:Vasculitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology
D007166:Immunosuppressive Agents