title: Real-time, once-daily monitoring of symptoms and FEV in cystic fibrosis patients--a feasibility study using a novel device.
abstract: OBJECTIVE
  We investigated feasibility and value of a real-time electronic monitoring system adapted for early detection of cystic fibrosis (CF) pulmonary exacerbations (P Exs).
  
  
  METHODS
  This was a 6-month prospective study. Patients recorded once daily their symptom score and spirometry using an electronic diary. The data were sent daily to the research team in real time. P Ex was considered to be present when change in symptoms and lung function values met a preset criteria. Number of P Exs during the study was compared with a parallel period of the previous and of the following years.
  
  
  RESULTS
  Only 19 patients (37.2%) completed recording that could be evaluated. A total of 53 P Exs were identified, 26 (49.0%) of which needed intravenous (IV) antibiotics. The number of total P Exs in the study year did not differ from the previous or the following year, but the number of courses of oral antibiotics was greater than those given during the previous year.
  
  
  CONCLUSIONS
  Remote daily monitoring of symptoms and spirometry had a poor uptake among CF patients. For those who completed the study, this method early detected P Exs that were treated with oral antibiotics that might otherwise required IV antibiotics.
authors.affiliation: Adult CF Centre, Department of Respiratory Medicine, Bristol Royal Infirmary, Bristol, UK.
authors.forename: Sunny
authors.initials: S
authors.lastname: Sarfaraz
authors.forename: Zoe
authors.initials: Z
authors.lastname: Sund
authors.forename: Nabil
authors.initials: N
authors.lastname: Jarad
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications* / Q000503:physiopathology; D018450:Disease Progression; D005240:Feasibility Studies; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008499:Medical Records; D010349:Patient Compliance; D011014:Pneumonia / Q000175:diagnosis*; D019095:Point-of-Care Systems; D013147:Spirometry / Q000295:instrumentation; D017216:Telemedicine