title: Early prophylactic pulmonary artery banding in isolated congenitally corrected transposition of the great arteries.
abstract: OBJECTIVE
  Mid-term evaluation of an aggressive surgical management of isolated congenitally corrected transposition of the great arteries (ccTGA) by pulmonary artery (PA) banding in early infancy.
  
  
  METHODS
  Between 2001 and 2009, 11 asymptomatic patients (seven neonates and four infants) underwent a dilatable, partially adjustable, homemade PA banding for ccTGA with intact ventricular septum. PA band circumference was correlated to body weight (22 mm+1 mm kg(-1)) and ideally adjusted to obtain flat septal geometry. Mean age at operation was 1.5±1.4 months.
  
  
  RESULTS
  There was no hospital mortality. Mean ventilation time and intensive care unit (ICU) stay were 20±9 h and 2.6±1.5 days, respectively. Five patients required postoperative inotropic support. One late death occurred suddenly at 4 months; normal biventricular function and no tricuspid regurgitation were noted at last follow-up, 1 week before death. Mean follow-up was 21.5±26 months. Mean band velocity increased over time from 2.65±0.7 m s(-1) postoperatively to 3.7±0.3 at 6 months and 4.5±0.4 m s(-1) at 2 years. Tricuspid regurgitation remained stable in seven patients, decreased in three and worsened in one. Flat septal geometry was obtained in all patients after the third postoperative month. One patient underwent a double-switch procedure at 7 years due to suprasystemic morphologically left ventricular pressure. The postoperative course was uneventful.
  
  
  CONCLUSIONS
  In neonates with isolated ccTGA, prophylactic PA banding is safe and carries a low morbidity. At mid-term evaluation, tricuspid valve function is stabilised or improved and systemic competence of the left ventricle is maintained, thus allowing double switch if indicated.
authors.affiliation: Department of Pediatric Cardiac Surgery, University Paris Descartes and Necker Sick Children Hospital, Paris, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Metton
authors.forename: Régis
authors.initials: R
authors.lastname: Gaudin
authors.forename: Phalla
authors.initials: P
authors.lastname: Ou
authors.forename: Sébastien
authors.initials: S
authors.lastname: Gerelli
authors.forename: Shafi
authors.initials: S
authors.lastname: Mussa
authors.forename: Daniel
authors.initials: D
authors.lastname: Sidi
authors.forename: Pascal
authors.initials: P
authors.lastname: Vouhé
authors.forename: Olivier
authors.initials: O
authors.lastname: Raisky
mesh_terms: D000367:Age Factors; D001783:Blood Flow Velocity / Q000502:physiology; D002316:Cardiotonic Agents / Q000627:therapeutic use; D003250:Constriction; D003422:Critical Care; D004812:Epidemiologic Methods; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D011182:Postoperative Care / Q000379:methods; D011651:Pulmonary Artery / Q000503:physiopathology / Q000601:surgery*; D012086:Reoperation / Q000379:methods; D014188:Transposition of Great Vessels / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D014262:Tricuspid Valve Insufficiency / Q000209:etiology
chemical_list: D002316:Cardiotonic Agents