[Risk factors associated to neonatal cross-infection].
BACKGROUND
Late-onset sepsis (occurring after 3 days of age) either cross-infection (CI) or perinatal is the first cause of morbidity and mortality in neonatal intensive care units (NICU) around the world. Our objective was to determine the current incidence of CI risk factors in neonates admitted to the NICU of the Hospital Civil de Guadalajara during a 9-month period.


METHODS
A case-control study with 114 newborns; 38 with CI and 76 controls. Odds ratio with 95 % confidence interval were calculated.


RESULTS
Associated risk factors were total parenteral nutrition (OR = 16.54, CI = 6.30-43.39, p < 0.001); weight < 1000 g (OR = 7.33, CI = 2.15-25.01, p < 0.001); intravascular catheter (OR = 6.79, CI = 2.68-17.00, p < 0.001); gestational age < 30 weeks (OR = 4.54, CI = 1.61-12.81, p < 0.003); intratracheal intubation and mechanical ventilation with (OR = 6.98, CI = 2.94-16.5, p < 0.001).


CONCLUSIONS
Total parenteral nutrition and weight < 1000 g showed the greatest association with cross-infection; in this study, male gender was not a risk factor.
Ramírez-Valdivia
Juan Manuel
JM
División de Pediatría OPD, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Jalisco, México. jramirez_valdivia@hotmail.com
Pérez-Molina
J Jesús
JJ
Villaseñor-Sierra
Alberto
A
Troyo-Sanromán
Rogelio
R
Gómez-Ruiz
Larissa María
LM
Farfán-Covarrubias
José Luis
JL
D016022:Case-Control Studies; D003428:Cross Infection / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology*; D008297:Male; D012307:Risk Factors