Joint disease mapping of cervical and male oropharyngeal cancer incidence in blacks and whites in South Carolina.
Human papillomavirus (HPV) infection is an established causal agent for cervical cancer and a subset of oropharyngeal cancers. It is hypothesized that orogenital transmission results in oral cavity infection. In this paper we explore the geographical association between cervical and male oropharyngeal cancer incidence in blacks and whites in South Carolina using Bayesian joint disease mapping models fit to publicly available data. Our results suggest weak evidence for county-level association between the diseases, and different patterns of joint disease behavior for blacks and whites.
Onicescu
Georgiana
G
Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, USA. onicescu@musc.edu
Hill
Elizabeth G
EG
Lawson
Andrew B
AB
Korte
Jeffrey E
JE
Gillespie
M Boyd
MB
D001499:Bayes Theorem; D044383:Black People / Q000706:statistics & numerical data*; D015984:Causality; D015897:Comorbidity; D005260:Female; D052162:Human papillomavirus 16 / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D007592:Joint Diseases / Q000175:diagnosis / Q000208:ethnology*; D008297:Male; D009959:Oropharyngeal Neoplasms / Q000208:ethnology* / Q000821:virology; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000208:ethnology* / Q000635:transmission; D016012:Poisson Distribution; D018570:Risk Assessment; D013022:South Carolina / Q000453:epidemiology; D019371:Topography, Medical; D002583:Uterine Cervical Neoplasms / Q000208:ethnology* / Q000821:virology; D044465:White People / Q000706:statistics & numerical data*; D001741:Black or African American