title: Preferential association between childhood emotional abuse and bipolar disorder.
abstract: Childhood trauma has been suggested to be involved in the susceptibility to bipolar disorder. However, case-control studies are lacking, and the preferential implication and the dose-effect of different trauma subtypes remain poorly investigated. Two hundred six bipolar patients and 94 controls completed the Childhood Trauma Questionnaire (CTQ; Bernstein et al., 1994). The CTQ total score was higher for bipolar patients than for controls. The presence of multiple trauma was significantly more frequent in bipolar patients than in controls (63% vs. 33%). Multiple logistic regression suggested that only emotional abuse was associated with bipolar disorder with a suggestive dose-effect. Clinical practice should include systematic assessment of childhood trauma among bipolar patients with a particular focus on emotional abuse.
authors.affiliation: INSERM, Unité 955 and Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Henri Mondor-Albert Chenevier, Pöle de Psychiatrie, Créteil Cedex, France. bruno.etain@inserm.fr
authors.forename: Bruno
authors.initials: B
authors.lastname: Etain
authors.forename: Flavie
authors.initials: F
authors.lastname: Mathieu
authors.forename: Chantal
authors.initials: C
authors.lastname: Henry
authors.forename: Aurélie
authors.initials: A
authors.lastname: Raust
authors.forename: Isabelle
authors.initials: I
authors.lastname: Roy
authors.forename: Anne
authors.initials: A
authors.lastname: Germain
authors.forename: Marion
authors.initials: M
authors.lastname: Leboyer
authors.forename: Frank
authors.initials: F
authors.lastname: Bellivier
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000209:etiology*; D002648:Child; D002649:Child Abuse / Q000523:psychology*; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires