title: Malabsorption syndrome and leukotriene inhibitor.
abstract: Previously described treatments used for eosinophilic diseases of the gastrointestinal tract have included dietary restrictions primarily of cow milk protein, anti-inflammatory therapy utilizing suplatast, budesonide and corticosteroids, cromolyn sodium, anti-histamines and oral inhalable steroids. We describe a 12-year-old girl with diarrhea and malabsorption, who was later diagnosed to have eosinophilic gastroenteritis, was unresponsive to standard therapies, but exhibited marked improvement with use of montelukast.
authors.affiliation: Department of Pediatrics, Sri Venkateswara Medical College and Research Institute, Arriyur, Puduchery, India.
authors.forename: Chinnakkannan
authors.initials: C
authors.lastname: Selva Kumar
authors.forename: Rashmi Ranjan
authors.initials: RR
authors.lastname: Das
authors.forename: C D
authors.initials: CD
authors.lastname: Balakrishnan
authors.forename: K
authors.initials: K
authors.lastname: Balagurunathan
authors.forename: Kaustabh
authors.initials: K
authors.lastname: Chaudhuri
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D002648:Child; D003521:Cyclopropanes; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis; D016099:Endoscopy, Gastrointestinal; D004751:Enteritis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005756:Gastritis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use*; D008286:Malabsorption Syndromes / Q000175:diagnosis / Q000209:etiology; D011804:Quinolines / Q000627:therapeutic use*; D013440:Sulfides; D016896:Treatment Outcome
chemical_list: D000085:Acetates; D003521:Cyclopropanes; D020024:Leukotriene Antagonists; D011804:Quinolines; D013440:Sulfides; C093875:montelukast