Regioselective functionalization of alkanes by sequential dehydrogenation-hydrozirconation.
We have succeeded in formal regioselective functionalization of alkanes by iridium-catalyzed dehydrogenation, hydrozirconation of the resulting alkenes, and electrophilic reaction of the generated alkylzirconium intermediate.
Kuninobu
Yoichiro
Y
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Kita-ku, Okayama 700-8530, Japan. kuninobu@cc.okayama-u.ac.jp
Ureshino
Tomonari
T
Yamamoto
Shun-ichi
S
Takai
Kazuhiko
K