title: [Ovarian cancer screening: recommendations for clinical pratice].
abstract: Ovarian cancer accounts for a minority of female cancers but remains the leading cause of death from gynaecologic cancers and the fifth leading cause of all cancer-related deaths among women. More than two thirds of cases of ovarian cancer are diagnosed once the disease becomes symptomatic, i.e. at an advanced stage. Though early detection constitutes a legitimate aim, no screening approach has yet been shown to reduce ovarian cancer mortality. In particular, ovarian imagery with endovaginal ultrasonography and serum tumor markers (CA-125) dosage performed in asymptomatic individuals have not proven their efficacy. Screening of asymptomatic women is not therefore recommended because of the limited prevalence of ovarian cancer in the general population.
authors.affiliation: Service d'oncologie, HUG, Geneva. marie-laure.amram@hcuge.ch
authors.forename: M-L
authors.initials: ML
authors.lastname: Amram-Benamran
authors.forename: S
authors.initials: S
authors.lastname: Cochet
authors.forename: P
authors.initials: P
authors.lastname: Petignat
authors.forename: A-P
authors.initials: AP
authors.lastname: Sappino
mesh_terms: D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D012307:Risk Factors