title: Community perceptions of bloody diarrhoea in an urban slum in South Asia: implications for introduction of a Shigella vaccine.
abstract: Understanding local perceptions of disease causation could help public health officials improve strategies to prevent bloody diarrhoea. A cross-sectional survey was conducted in Dhaka, Bangladesh to elicit community beliefs about the causes of and prevention strategies for bloody diarrhoea. Between March and June 2003, we interviewed 541 randomly selected respondents. Overall, 507 (93%) respondents perceived that a vaccine could prevent bloody diarrhoea. If a vaccine provided lifetime protection, 445 (83%) respondents stated that they would opt to get the vaccine and would pay a median of $0·05 (range U.S.$0·01-0·15) for it, equivalent to <1% of their median weekly income. There was almost universal perception that an effective vaccine to prevent bloody diarrhoea was highly beneficial and acceptable. While respondents valued a vaccine for prevention of bloody diarrhoea, they were only willing to pay minimally for it. Therefore, achieving a high rate of Shigella vaccine coverage may require subsidy of vaccine purchase.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, GA, USA. warvelo@gt.cdc.gov
authors.forename: W
authors.initials: W
authors.lastname: Arvelo
authors.forename: L S
authors.initials: LS
authors.lastname: Blum
authors.forename: N
authors.initials: N
authors.lastname: Nahar
authors.forename: L
authors.initials: L
authors.lastname: von Seidlein
authors.forename: L
authors.initials: L
authors.lastname: Nahar
authors.forename: R P
authors.initials: RP
authors.lastname: Pack
authors.forename: A W
authors.initials: AW
authors.lastname: Brooks
authors.forename: A
authors.initials: A
authors.lastname: Pach
authors.forename: R F
authors.initials: RF
authors.lastname: Breiman
authors.forename: S P
authors.initials: SP
authors.lastname: Luby
authors.forename: P K
authors.initials: PK
authors.lastname: Ram
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001459:Bangladesh / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004405:Dysentery, Bacillary / Q000453:epidemiology* / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D011204:Poverty Areas; D022281:Shigella Vaccines / Q000191:economics / Q000276:immunology*; D014611:Vaccination / Q000191:economics / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D022281:Shigella Vaccines