title: A synthesis of the C1-C15 domain of the halichondrins.
abstract: A concise route to the C1-C15 domain of the halichondrins is described. The key reaction is the conversion of a furfuryl alcohol to a pyranone. The stereocenter of this pyranone serves as the starting point for the other 8 stereocenters.
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309-0215, USA.
authors.forename: Katrina L
authors.initials: KL
authors.lastname: Jackson
authors.forename: James A
authors.initials: JA
authors.lastname: Henderson
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Morris
authors.forename: Hajime
authors.initials: H
authors.lastname: Motoyoshi
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Phillips