title: [Prediction of the GVHD after allo-HSCT by sequence similar matching method].
abstract: This study was aimed to investigate the role of sequence similar matching (SSM) method in prediction of GVHD after HLA unmatched allogeneic hematopoietic stem cell transplantation (allo-HSCT). The data from 23 patients undergoing HLA unmatched allo-HSCT were analyzed and calculated by SSM method. The results showed that the incidence of acute and severe GVHD were significantly less in the allo-HSCT cases with total SSM value less than 55. In conclusion, the SSM method can be used to predict GVHD in the HLA-unmatched allogeneic hematopoietic stem cell transplantation.
authors.affiliation: Department of Hematology, 304th Clinical Division, Chinese PLA General Hospital, Beijing 100048 China.
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Zhao
authors.forename: Zhou-Yang
authors.initials: ZY
authors.lastname: Liu
authors.forename: Yong-Bin
authors.initials: YB
authors.lastname: Cao
authors.forename: Shuang
authors.initials: S
authors.lastname: Jiang
authors.forename: Wan-Ming
authors.initials: WM
authors.lastname: DA
authors.forename: Xiao-Xiong
authors.initials: XX
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006086:Graft vs Host Disease / Q000175:diagnosis* / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects* / Q000379:methods; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous / Q000009:adverse effects; D055815:Young Adult