Biomechanical and microscopic response of bone to titanium implants in the presence of inorganic grafts.
This study evaluated the biomechanical and microscopic response of previously grafted bone to titanium implants. The lower incisors of 16 rabbits were surgically extracted, and bilateral perforations communicating with the remaining sockets were created distally. A socket/perforation defect on each mandible was chosen at random to be immediately filled with a xenogenic graft, whereas the contralateral perforation was left to heal naturally and served as a paired control. After 60 days, titanium implants were installed in the previously operated areas. After periods of 2 and 6 months, the animals were killed, and the force necessary to retrieve implants as well as the bone-implant contact (BIC) and bone mass (BM) were quantified and statistically compared by 2-way analysis of variance and Tukey's test (α  =  .05). No significant differences in removal torque were observed, either by time or by treatment condition. Differences in BIC and BM between experimental and control groups were not statistically significant through the intervals studied (P < .05). The presence of a xenogenic graft did not influence the microscopic tissue response to titanium implants or fixation into newly formed or mature bone.
Munhoz
Etiene Andrade
EA
Department of Stomatology and Oral Surgery, School of Dentistry, University of São Paulo, Bauru, Brazil. etiamfob@yahoo.com
Bodanezi
Augusto
A
Cestari
Tania Mary
TM
Taga
Rumio
R
Ferreira Junior
Osny
O
de Carvalho
Paulo Sergio Perri
PS
D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000502:physiology; D016025:Bone Transplantation / Q000379:methods*; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D008297:Male; D008334:Mandible / Q000473:pathology* / Q000601:surgery; D008338:Mandibular Injuries / Q000473:pathology / Q000601:surgery; D016348:Osseointegration / Q000502:physiology; D010006:Osteoblasts / Q000166:cytology; D010011:Osteocytes / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits; D013314:Stress, Mechanical; D013997:Time Factors; D014025:Titanium / Q000737:chemistry; D020390:Tooth Socket / Q000473:pathology / Q000601:surgery; D019415:Torque; D014183:Transplantation, Heterologous; D014945:Wound Healing / Q000502:physiology
D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium