title: Impella 2.5.
abstract: Impella 2.5 (Abiomed Inc., Danvers, Ma.) is a percutaneous microaxial circulatory support pump that delivers up to 2.5 l/min of systemic flow augmentation by pumping directly from the left ventricle into the ascending aorta. This article describes the device including the insertion method, fundamental principles of action, and clinical results from the completed Protect I clinical trial as well as general use under FDA clearance.
authors.affiliation: Abiomed, Danvers, MA, USA. draess@abiomed.com
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Raess
authors.forename: David M
authors.initials: DM
authors.lastname: Weber
mesh_terms: D000818:Animals; D018849:Controlled Clinical Trials as Topic; D018795:Device Approval; D004867:Equipment Design; D019317:Evidence-Based Medicine; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome; D014481:United States; D016277:Ventricular Function, Left