title: Application of k-space energy spectrum analysis for inherent and dynamic B0 mapping and deblurring in spiral imaging.
abstract: Spiral imaging is vulnerable to spatial and temporal variations of the amplitude of the static magnetic field (B(0)) caused by susceptibility effects, eddy currents, chemical shifts, subject motion, physiological noise, and system instabilities, resulting in image blurring. Here, a novel off-resonance correction method is proposed to address these issues. A k-space energy spectrum analysis algorithm is first applied to inherently and dynamically generate a B(0) map from the k-space data at each time point, without requiring any additional data acquisition, pulse sequence modification, or phase unwrapping. A simulated phase evolution rewinding algorithm and an automatic residual deblurring algorithm are then used to correct for the blurring caused by both spatial and temporal B(0) variations, resulting in a high spatial and temporal fidelity. This method is validated against conventional B(0) mapping and deblurring methods, and its advantages for dynamic MRI applications are demonstrated in functional MRI studies.
authors.affiliation: Brain Imaging and Analysis Center, Duke University, Durham, North Carolina, USA. truong@biac.duke.edu
authors.forename: Trong-Kha
authors.initials: TK
authors.lastname: Truong
authors.forename: Nan-Kuei
authors.initials: NK
authors.lastname: Chen
authors.forename: Allen W
authors.initials: AW
authors.lastname: Song
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity