title: Sclerostin: a gem from the genome leads to bone-building antibodies.
authors.affiliation: Metabolic Disorders, Amgen Inc, Thousand Oaks, CA 91320-1799, USA. cpaszty@amgen.com
authors.forename: Chris
authors.initials: C
authors.lastname: Paszty
authors.forename: Charles H
authors.initials: CH
authors.lastname: Turner
authors.forename: Martyn K
authors.initials: MK
authors.lastname: Robinson
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D000906:Antibodies / Q000276:immunology* / Q000494:pharmacology; D001846:Bone Development / Q000187:drug effects / Q000276:immunology / Q000502:physiology*; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000502:physiology*; D001842:Bone and Bones / Q000166:cytology / Q000502:physiology; D005819:Genetic Markers / Q000235:genetics / Q000502:physiology*; D016678:Genome; D006023:Glycoproteins; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D051379:Mice; D018345:Mice, Knockout; D010281:Parathyroid Hormone / Q000502:physiology; D015398:Signal Transduction
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D000906:Antibodies; D019485:Bone Morphogenetic Proteins; D005819:Genetic Markers; D006023:Glycoproteins; D036341:Intercellular Signaling Peptides and Proteins; D010281:Parathyroid Hormone; C486030:Sost protein, mouse