Successful treatment for carriage of methicillin-resistant Staphylococcus aureus and importance of follow-up.
With this prospective observational follow-up study of 165 methicillin-resistant Staphylococcus aureus (MRSA)-positive individuals (23 health care workers and 142 patients), we determined that our MRSA eradication therapy protocol results in a high success rate (81%). Five or more negative culture sets give a predictive value for MRSA eradication therapy success of >90%. Furthermore, MRSA colonization, at least in the throat, and the presence of wounds just before the start of MRSA eradication therapy are associated with MRSA eradication therapy failure.
Mollema
F P N
FP
Erasmus University Medical Center Rotterdam, Department of Medical Microbiology & Infectious Diseases, Postbus 2040, 3000 CA Rotterdam, The Netherlands.
Severin
J A
JA
Nouwen
J L
JL
Ott
A
A
Verbrugh
H A
HA
Vos
M C
MC
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000472:pathogenicity; D008875:Middle Aged; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology*; D055815:Young Adult
D000900:Anti-Bacterial Agents