title: Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species.
abstract: Diketopiperazine (DKP) derivatives, named colletopiperazine, fusaperazine C and E as well as four known DKPs were isolated from cultures of Colletotrichum gloeosporioides, Penicillium crustosum, both endophytic fungi isolated from Viguiera robusta, and a Fusarium spp., an endophyte of Viguiera arenaria, respectively. Their structures were established on the basis of their spectroscopic data. Conformational analysis of two known DKPs showed that folded conformations were as energetically stable as the extended one.
authors.affiliation: Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903 Ribeirão Preto, SP, Brazil.
authors.forename: Denise O
authors.initials: DO
authors.lastname: Guimarães
authors.forename: Warley S
authors.initials: WS
authors.lastname: Borges
authors.forename: Noemi J
authors.initials: NJ
authors.lastname: Vieira
authors.forename: Laiani F
authors.initials: LF
authors.lastname: de Oliveira
authors.forename: Carlos H T P
authors.initials: CH
authors.lastname: da Silva
authors.forename: Norberto P
authors.initials: NP
authors.lastname: Lopes
authors.forename: Luis G
authors.initials: LG
authors.lastname: Dias
authors.forename: Rosa
authors.initials: R
authors.lastname: Durán-Patrón
authors.forename: Isidro G
authors.initials: IG
authors.lastname: Collado
authors.forename: Mônica T
authors.initials: MT
authors.lastname: Pupo
mesh_terms: D019659:Asteraceae / Q000145:classification / Q000382:microbiology*; D020231:Colletotrichum / Q000737:chemistry; D054659:Diketopiperazines / Q000737:chemistry / Q000302:isolation & purification*; D005658:Fungi / Q000737:chemistry / Q000302:isolation & purification*; D005670:Fusarium / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry
chemical_list: D054659:Diketopiperazines