Suppression of ventricular tachycardia with dronedarone: a case report.
BACKGROUND
Dronedarone is a multichannel blocker with similar electrophysiological properties to amiodarone. Dronedarone has not been studied in humans as an agent to suppress ventricular arrhythmias.


METHODS
This case report describes the dramatic antiarrhythmic effects of dronedarone in a patient with nonischemic cardiomyopathy and recurrent ventricular tachycardia, which was resistant to multiple antiarrhythmic agents and endocardial catheter ablation.


RESULTS
Dronedarone was effective in completely suppressing ventricular tachycardia.


CONCLUSIONS
Further research is needed to establish a potential larger role for dronedarone in controlling ventricular arrhythmias in humans.
Shaaraoui
Mustaphasahim
M
Cardiovascular Division, Department of Medicine, Lehigh Valley Hospital, Allentown, Pennsylvania, USA. Mustapha_H.Shaaraoui@lvhn.org
Freudenberger
Ronald
R
Levin
Vadim
V
Marchlinski
Francis E
FE
D000328:Adult; D000638:Amiodarone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control*; D000077764:Dronedarone; D006801:Humans; D008297:Male; D055502:Secondary Prevention; D017180:Tachycardia, Ventricular / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control*; D016896:Treatment Outcome
D000889:Anti-Arrhythmia Agents; D000077764:Dronedarone; D000638:Amiodarone