Pigmented deposits on a Boston keratoprosthesis from topical ibopamine.
OBJECTIVE
To report a case of pigmented deposits on a type I Boston keratoprosthesis (KPro) associated with the use of topical ibopamine as a treatment for hypotony.


METHODS
Case report and literature review.


RESULTS
The dopamine-like agent ibopamine caused black deposits on the bandage lens and on the front plate of the Boston KPro that resulted in reduced visual acuity. Change to a daily disposable contact lens and regular cleaning of the KPro front plate with diluted baby shampoo eliminated this problem.


CONCLUSIONS
This is the first report of this complication with topical ibopamine use and should be considered when ibopamine is used chronically for hypotony.
Kanoff
Justin M
JM
Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Colby
Kathryn
K
D000287:Administration, Topical; D001187:Artificial Organs; D003846:Deoxyepinephrine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D018491:Dopamine Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008543:Melanins / Q000737:chemistry; D008548:Melanosis / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D015814:Ocular Hypotension / Q000188:drug therapy; D019736:Prostheses and Implants; D011475:Prosthesis Failure
D018491:Dopamine Agonists; D008543:Melanins; C023487:ibopamine; D003846:Deoxyepinephrine