title: Correlations between aorto-popliteal bolus transit speed and aortic and popliteal bolus transit time during CT angiography of aortoiliac and lower extremity arteries.
abstract: OBJECTIVE
  The purpose of this study was to investigate correlations between the aorto-popliteal bolus transit speed and aortic and popliteal bolus transit time in order to evaluate the possibility for prediction of bolus transit speed by single test injection technique.
  
  
  METHODS
  Approval was obtained from our institutional review board for this study, which included 42 patients, from all of whom written informed consent was obtained. Low-dose serial CT scanning after injection of 12 ml contrast material (300 mg/ml) at a rate of 3 ml/s followed by saline flush was performed twice, first at the level of the upper abdomen and second at the level of the knee joint. The times needed to reach peak enhancement of the upper abdominal aorta (T-aorta) and bilateral popliteal arteries (T-popliteal) were obtained, and aorto-popliteal bolus transit speeds between the abdominal aorta and popliteal arteries were calculated. ABI was recorded for the bilateral feet. The Pearson's product-moment correlation coefficient was used to investigate the correlation between the bolus transit speed and T-aorta, T-popliteal, ABI, and patient age.
  
  
  RESULTS
  The respective correlation coefficients for bolus transit speed on the one hand and T-aorta, T-popliteal, ABI, patient age on the other were -0.50, -0.84, 0.36, and -0.52.
  
  
  CONCLUSIONS
  The time to peak enhancement for popliteal arteries showed the strongest correlation with aorto-popliteal bolus transit speeds, and was considered to be the most accurate predictor for aorto-popliteal bolus transit speeds.
authors.affiliation: Department of Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan. y-nakaya@radiol.med.osaka-u.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nakaya
authors.forename: Tonsok
authors.initials: T
authors.lastname: Kim
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Hori
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Onishi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakamoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuboyama
authors.forename: Noboru
authors.initials: N
authors.lastname: Maeda
authors.forename: Hiroki
authors.initials: H
authors.lastname: Higashihara
authors.forename: Kaname
authors.initials: K
authors.lastname: Tomoda
authors.forename: Hironobu
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography / Q000379:methods*; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007472:Iohexol / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging*; D011150:Popliteal Artery / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol