title: Hit identification and biological evaluation of anticancer pyrazolopyrimidines endowed with anti-inflammatory activity.
authors.affiliation: Dipartimento di Scienze Farmacobiologiche, Università degli Studi "Magna Graecia" di Catanzaro, Italy. alcaro@unicz.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Alcaro
authors.forename: Anna
authors.initials: A
authors.lastname: Artese
authors.forename: Maurizio
authors.initials: M
authors.lastname: Botta
authors.forename: Alessandra T
authors.initials: AT
authors.lastname: Zizzari
authors.forename: Francisco
authors.initials: F
authors.lastname: Orallo
authors.forename: Francesco
authors.initials: F
authors.lastname: Ortuso
authors.forename: Silvia
authors.initials: S
authors.lastname: Schenone
authors.forename: Chiara
authors.initials: C
authors.lastname: Brullo
authors.forename: Matilde
authors.initials: M
authors.lastname: Yáñez
mesh_terms: D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D001665:Binding Sites; D045744:Cell Line, Tumor; D003198:Computer Simulation; D051545:Cyclooxygenase 1 / Q000737:chemistry / Q000378:metabolism; D051546:Cyclooxygenase 2 / Q000737:chemistry / Q000378:metabolism; D052246:Cyclooxygenase 2 Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D016861:Cyclooxygenase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D011720:Pyrazoles; D011725:Pyridines; C118531:pyrazolopyridine; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2