Optoelectronic tweezers as a tool for parallel single-cell manipulation and stimulation.
Optoelectronic tweezers (OET) is a promising approach for the parallel manipulation of single cells for a variety of biological applications. By combining the manipulation capabilities of OET with other relevant biological techniques (such as cell lysis and electroporation), one can realize a true parallel, single-cell diagnostic and stimulation tool. Here, we demonstrate the utility of the OET device by integrating it onto single-chip systems capable of performing in-situ, electrode-based electroporation/lysis, individual cell, light-induced lysis, and light-induced electroporation.
Valley
J K
JK
Ohta
A T
AT
Hsan-Yin Hsu
Neale
S L
SL
Jamshidi
A
A
Wu
M C
MC