[The importance of updating criteria of altered fasting glucose levels in Mexico].
OBJECTIVE
To evaluate the impact of applying the 2003-ADA-proposed lower normality value of fasting glucose (FG) on impaired fasting glucose (IFG), prevalence and the agreement between diagnostic categories from ADA-2003 FG values and WHO two hours oral glucose tolerance test (OGTT) current criteria in a Mexican population with suspected diabetes.


METHODS
A retrospective cross sectional study was undertaken. We analyzed fasting and 2 hours post load glucose values of 2062 patients and compared diagnostic categories on the basis of different criteria.


RESULTS
Considering fasting values, prevalence of IFG changed from 17.7 % to 41.3 % when applying ADA-1997 or ADA-2003 criteria, respectively. Furthermore, based on their OGTT values (WHO-1999), 63 % the 852 IFG patients identified by ADA-2003 criteria were reclassified as having diabetes (26.1 %) or IGT (36.9 %). A heavy kappa test showed a moderate diagonal agreement of 0.43260 (CI 95 % = 0.43214-0.43305) between diagnostic categories from ADA-2003 with FG and OGTT values and WHO current criteria.


CONCLUSIONS
The lower ADA-2003 criteria for IFG identifies a higher ratio of patients with IGT or DM.
Pérez-Jáuregui
José
J
Dirección Corporativa de Medicina de Laboratorio, Laboratorio Médico del Chopo, Distrito Federal, México. jperezj@medicasur.org.mx
Reza-Albarrán
Alfredo
A
González-Cardel
Ana María
AM
Olay-Fuentes
Gabriela
G
Fagundo-Sierra
Reynerio
R
Cortez-Gómez
Rudyard
R
D001786:Blood Glucose / Q000032:analysis*; D003430:Cross-Sectional Studies; D005215:Fasting / Q000097:blood*; D006801:Humans; D008800:Mexico; D012016:Reference Values; D012189:Retrospective Studies
D001786:Blood Glucose