[Influence of intervene of traditional Chinese medicine on cytokine level in benign prostatic hyperplasia].
OBJECTIVE
To make a study of the influence of the intervene of traditional Chinese medicine on cytokine level in benign prostatic hyperplasia.


METHODS
The patients were divided into treatment group (group A), control group (group B) and healthy group (group C) with the randomly compared researching method. Group A were given Qianliening Tang (QLNT), daily potion, two times a day. Group B were given Qianliekang, three times a day, three pills each time. The course of both treatment lasted for 8 weeks.


RESULTS
Before treatment, TNF-alpha, IL-17/IL-10, IL-4 in group A and B are obviously out of order compared with group C (P < 0.01). After the treatment, TNF-alpha, IL-17 in group A decreased dramatically and IL-10, IL-4 increased, which shows great differences compared with those before treatment and with group B (P < 0.01), but still can't reach to group C level.


CONCLUSIONS
Qian liening Tang can efficiently regulate the level of suppressive inflammatory cytokines and proinflammatory cytokines. It provides scientific experimental basis for clinical diagnosis and treatment of the disease.
Wang
Hao
H
School of Medicine, Jinhua College of Profession and Technology, Jinhua 321017, China. wanghao9864@163.com
Shu
Yuemin
Y
Zheng
Haiwen
H
Wu
Dong
D
Huang
Binlun
B
Gao
Suhua
S
D000276:Adjuvants, Immunologic; D000368:Aged; D000369:Aged, 80 and over; D016207:Cytokines / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D007371:Interferon-gamma / Q000097:blood; D016753:Interleukin-10 / Q000097:blood; D020381:Interleukin-17 / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D007963:Leukocytes, Mononuclear / Q000187:drug effects*; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D008517:Phytotherapy; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000188:drug therapy; D012333:RNA, Messenger; D013583:Synovial Membrane / Q000187:drug effects; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D000276:Adjuvants, Immunologic; D016207:Cytokines; D004365:Drugs, Chinese Herbal; D020381:Interleukin-17; D012333:RNA, Messenger; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D015847:Interleukin-4; D007371:Interferon-gamma