[Increased prevalence of depression in hepatitis C infection patients].
The prevalence of depression is increased in patients with chronic hepatitis C virus (HCV) infection. Several aetiological mechanisms are thought to be involved, e.g. premorbid psychiatric disease, genetic disposition to affective disorders, socio-economic factors, stigmatization and possibly HCV neuroinfection. Evidence to support that former intravenous drug abuse increases the risk of depression is lacking. It is particularly important to diagnose and treat depression in HCV patients as it constitutes a relative contraindication to antiviral treatment and may jeopardize therapeutic outcome.
Hjerrild
Simon
S
Center for Psykiatrisk Forskning, Arhus Universitetshospital, Risskov, 8240 Risskov, Denmark. bauhjerrild@gmail.com
Renvillard
Signe Groth
SG
Leutscher
Peter Derek Christian
PD
Videbech
Poul
P
D000998:Antiviral Agents; D001921:Brain / Q000821:virology; D000075202:Contraindications; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D020022:Genetic Predisposition to Disease; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000821:virology; D006801:Humans; D001523:Mental Disorders / Q000150:complications; D015995:Prevalence; D012307:Risk Factors
D000998:Antiviral Agents