title: Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: insights from baseline findings in the circumpolar Inuit health in transition cohort study.
abstract: BACKGROUND
  The Inuit are commonly portrayed to be somehow protected from cardiovascular diseases (CVDs) through their traditional lifestyle and diet. However, actual sociocultural transition and related major, modifiable risk factors have scarcely been quantified in the Inuit population. Such knowledge is extremely valuable in terms of public health intervention.
  
  
  METHODS
  A total of 887 Inuit residents from Nunavik, Quebec, participated in a cohort study. The estimates presented were derived from anthropometric and biological measurements gathered at the time of recruitment and enhanced by information collected in the medical file of each participant. All estimates were corrected for a complex sampling strategy and bootstrapped to ensure the representativeness of the general Nunavik population.
  
  
  RESULTS
  Overall, 19% of Inuit had a disease of the circulatory system according to the International Statistical Classification of Diseases and Related Health Problems, 10th revision. Among all disorders, peripheral circulatory system disease was the most prevalent (9%). Prevalences of ischemic heart disease and cerebrovascular disease were of similar magnitude (2.5%). No significant difference in disease prevalence was noted between sexes. The major modifiable CVD risk factors were smoking (84%), obesity (49%) [corrected] (body mass index of greater than 30 kgm2) and elevated blood pressure (13085 mmHg or greater) (18%). Prevalences were globally higher among women.
  
  
  CONCLUSIONS
  The current belief that the Inuit are protected from CVD is seriously questioned by the results of the present study. Considering the extremely high prevalence of CVD risk factors, a population-based intervention reinforced for women is urgently needed to reduce their risk.
authors.affiliation: School of Dietetics and Human Nutrition, McGill University, Montreal, Canada. marie-ludivine.chateau-degat@crchul.ulaval.ca
authors.forename: Marie-Ludivine
authors.initials: ML
authors.lastname: Chateau-Degat
authors.forename: Eric
authors.initials: E
authors.lastname: Dewailly
authors.forename: Rabia
authors.initials: R
authors.lastname: Louchini
authors.forename: Emilie
authors.initials: E
authors.lastname: Counil
authors.forename: Martin
authors.initials: M
authors.lastname: Noël
authors.forename: Annie
authors.initials: A
authors.lastname: Ferland
authors.forename: Michel
authors.initials: M
authors.lastname: Lucas
authors.forename: Béatriz
authors.initials: B
authors.lastname: Valera
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Ekoé
authors.forename: Robert
authors.initials: R
authors.lastname: Ladouceur
authors.forename: S
authors.initials: S
authors.lastname: Déry
authors.forename: Grace
authors.initials: G
authors.lastname: Egeland
mesh_terms: D002318:Cardiovascular Diseases / Q000208:ethnology* / Q000209:etiology; D004032:Diet; D005260:Female; D005500:Follow-Up Studies; D019456:Health Transition; D006801:Humans; D015994:Incidence; D004930:Inuit; D008019:Life Style; D008297:Male; D009765:Obesity / Q000150:complications / Q000208:ethnology; D015995:Prevalence; D011792:Quebec / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000208:ethnology