Rhinoscleroma causing severe bilateral nasal obstruction.
Rhinoscleroma is a chronic, infectious and granulomatous disease of the respiratory tract. There is often a delay in diagnosis due to unfamiliarity with the disease and also because culture is not always positive. We report a case in a 26-year-old woman with granular mass obstructing bilateral nasal cavities and causing breathing difficulty. Histopathological examination showed characteristic Mikulicz histiocytes containing numerous Gram-negative intracellular rod-shaped bacilli consistent with the diagnosis of rhinoscleroma. The patient was treated with gemifloxacin and tetracycline and remains asymptomatic over a year follow-up period. It is important to consider rhinoscleroma in cases of chronic nasal obstruction. As culture is not always positive, histopathological examination may be crucial to the diagnosis.
Moraes
Mário Augusto Pinto de
MA
Department of Pathology, Hospital Universitário de Brasília, UNB Via L2 Norte, Brasília, Brazil.
Magalhães
Albino Verçosa de
AV
Marinho
Larissa Cardoso
LC
Azevedo
Ana Emília Borges de
AE
Carneiro
Fabiana Pirani
FP
Raymundo
Igor Teixeira
IT
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D024841:Fluoroquinolones / Q000627:therapeutic use; D000077735:Gemifloxacin; D006801:Humans; D009287:Naphthyridines / Q000627:therapeutic use; D015508:Nasal Obstruction / Q000188:drug therapy / Q000209:etiology*; D012226:Rhinoscleroma / Q000150:complications* / Q000188:drug therapy; D013752:Tetracycline / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; D013752:Tetracycline; D000077735:Gemifloxacin