Two new bisindole alkaloids from the seeds of Strychnos nux-vomica.
The reinvestigation of Strychnos nux-vomica resulted in the isolation of two colorless monoquaternary bisindole alkaloids from the seeds. The structures of the two new compounds named 4-N-hydroxymethyl strychnidin-17-acetic acid (1) and 10, 11-dimethoxy-4-N-hydroxymethyl strychnidin-17-acetic acid (2), were defined by detailed spectral analyses, especially (1)H NMR, (13)C NMR, DEPT, HSQC, (1)H NMR-(1)H NMR, NOESY, HMBC and TOF-MS.
Yang
Guang-Ming
GM
Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210029, China.
Tu
Xia
X
Liu
Liang-Jing
LJ
Pan
Yang
Y
D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds; D031451:Strychnos / Q000737:chemistry*
C557762:10,11-dimethoxy-4-N-hydroxymethyl strychnidin-17-acetic acid; C557763:4-N-hydroxymethyl strychnidin-17-acetic acid; D026121:Indole Alkaloids; D010936:Plant Extracts