title: Low-fiber diet in limited bowel preparation for CT colonography: Influence on image quality and patient acceptance.
abstract: OBJECTIVE
  The purpose of this study was to determine whether a low-fiber diet is necessary for optimal tagging-only bowel preparation for CT colonography.
  
  
  METHODS
  Fifty consecutively enrolled patients received an iodine bowel preparation: 25 patients used a low-fiber diet and 25 used no special diet. One observer determined the tagging quality per segment on a 5-point scale (1, inhomogeneous tagging; 5, excellent preparation) and the largest size of untagged feces. Semiautomatic measurements of density and homogeneity of residual feces were performed. Patient acceptance was assessed with questionnaires. Per polyp sensitivity for polyps 6 mm in diameter and larger was calculated for two experienced observers.
  
  
  RESULTS
  Tagging quality was scored less than grade 5 in 15 segments (10%) in the low-fiber diet group and in 25 segments (17%) in the unrestricted diet group (p = 0.098). One piece of untagged feces 10 mm in diameter or larger was found in the low-fiber diet group, and 12 were found in the unrestricted diet group (p < 0.001). Automatic measurement of attenuation resulted in a mean value of 594 HU in the low-fiber diet group and 630 HU in the unrestricted diet group (p = 0.297). In the low-fiber diet group, 22% of patients indicated that the bowel preparation was extremely or severely burdensome; 8% of patients in the unrestricted diet group had this response (p = 0.19). Thirty-two polyps 6 mm in diameter or larger were found in the low-fiber diet group and 30 in the unrestricted diet group. Observer 1 had 84% and 77% sensitivity in detecting polyps 6 mm in diameter or larger in the low-fiber diet and unrestricted diet groups, respectively (p = 0.443), and observer 2 had 97% and 83% sensitivity (p = 0.099).
  
  
  CONCLUSIONS
  Use of a low-fiber diet in bowel preparation for CT colonography results in significantly less untagged feces and shows a trend toward better residue homogeneity.
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, The Netherlands. m.h.liedenbaum@amc.uva.nl <m.h.liedenbaum@amc.uva.nl>
authors.forename: Marjolein H
authors.initials: MH
authors.lastname: Liedenbaum
authors.forename: Maaike J
authors.initials: MJ
authors.lastname: Denters
authors.forename: Ayso H
authors.initials: AH
authors.lastname: de Vries
authors.forename: Vincent F
authors.initials: VF
authors.lastname: van Ravesteijn
authors.forename: Shandra
authors.initials: S
authors.lastname: Bipat
authors.forename: Frans M
authors.initials: FM
authors.lastname: Vos
authors.forename: Evelien
authors.initials: E
authors.lastname: Dekker
authors.forename: Jaap
authors.initials: J
authors.lastname: Stoker
mesh_terms: D016009:Chi-Square Distribution; D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic; D003113:Colonoscopy; D003287:Contrast Media; D004043:Dietary Fiber; D005260:Female; D006801:Humans; D007422:Intestines / Q000000981:diagnostic imaging*; D007482:Iothalamate Meglumine; D007552:Isotonic Solutions / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009780:Occult Blood; D010342:Patient Acceptance of Health Care; D011092:Polyethylene Glycols / Q000008:administration & dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires
chemical_list: D003287:Contrast Media; D004043:Dietary Fiber; D007552:Isotonic Solutions; C520497:MoviPrep; C112283:klean prep; D011092:Polyethylene Glycols; C001694:meglumine ioxithalamate; D007482:Iothalamate Meglumine