title: Persistence of ventilatory defect after resolution of pulmonary interstitial emphysema in a preterm baby.
abstract: Pulmonary interstitial emphysema is a common complication of mechanical ventilation in preterm babies. We report a case of severe unilateral pulmonary interstitial emphysema in a premature newborn, treated with high-frequency oscillatory ventilation, lateral decubitus positioning and selective intubation. After complete radiological resolution of the pulmonary emphysema in the left lung, the patient was studied by electrical impedance tomography and a marked reduction of ventilation was identified in the left lung despite radiological resolution of the cysts. This finding indicates that functional abnormalities may persist for longer periods after radiologic resolution of such lesions.
authors.affiliation: Clínica de Especialidades Pediátricas, Hospital Israelita Albert Einstein, São Paulo, Brazil.
authors.forename: Luiz Vicente Ferreira da Silva
authors.initials: LV
authors.lastname: Filho
authors.forename: Felipe De Souza
authors.initials: Fde S
authors.lastname: Rossi
authors.forename: Alice d'Agostini
authors.initials: Ad
authors.lastname: Deutsch
authors.forename: Ana Cristina Zanon
authors.initials: AC
authors.lastname: Yagui
authors.forename: Karina
authors.initials: K
authors.lastname: Timenetsky
authors.forename: Celso de Moura
authors.initials: Cde M
authors.lastname: Rebello
mesh_terms: D000328:Adult; D005260:Female; D006612:High-Frequency Ventilation; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology; D007235:Infant, Premature, Diseases / Q000628:therapy*; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011656:Pulmonary Emphysema / Q000150:complications / Q000628:therapy*; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications / Q000628:therapy; D012131:Respiratory Insufficiency / Q000150:complications / Q000175:diagnosis*; D017211:Treatment Failure; D014427:Twins