title: Heyde syndrome--the link between aortic stenosis and gastrointestinal bleeding.
abstract: Aortic valve stenosis can be complicated by gastrointestinal bleeding from angiodysplasia. A deficiency of high molecular weight multimers of von Willebrand factor (vWF) (type 2A von Willebrand disease) provides the link between this association, which is known as Heyde syndrome. Aortic valve replacement corrects the vWF abnormalities with long-term resolution of gastrointestinal bleeding. The authors present a case report and a review of this association.
authors.affiliation: Serviço de Medicina I, Hospital S. Teotónio, Viseu, Portugal. xana.vaz29@gmail.com
authors.forename: Alexandra
authors.initials: A
authors.lastname: Vaz
authors.forename: Andreia
authors.initials: A
authors.lastname: Correia
authors.forename: Borges
authors.initials: B
authors.lastname: Martins
authors.forename: Joana
authors.initials: J
authors.lastname: Capelo
authors.forename: Pedro
authors.initials: P
authors.lastname: Ferreira
authors.forename: Pedro
authors.initials: P
authors.lastname: Henriques
authors.forename: Oliveira
authors.initials: O
authors.lastname: Santos
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000150:complications*; D001024:Aortic Valve Stenosis / Q000150:complications*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D013577:Syndrome