Anaplasma phagocytophilum in livestock and small rodents.
To identify the prevalence of Anaplasma phagocytophilum in both wild rodents and domestic animals and to make clear the genetic characteristics of the agents from different animals in China, a total of 105 livestock and 159 small rodents were analyzed by real-time-PCR and sequence analysis. The prevalence rate was 6.7% (7/105) and 14.5% (23/159), respectively. The nucleotide sequences of 16S rRNA (rrs) from the positive livestock and rodents were identical to each other. The phylogenetic analysis based on partial A. phagocytophilum p44ESup1 gene revealed that A. phagocytophilum identified in this study was placed on a separate clade distinct from those in other continents. These findings indicated A. phagocytophilum in rodents might be able to infect livestock and intensified the threats of anaplasmosis to livestock in the area. Further studies on public health significance of the agent are worth investigation in future.
Zhan
Lin
L
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong-Da Street, Fengtai District, Beijing 100071, People's Republic of China.
Cao
Wu-Chun
WC
Jiang
Jia-Fu
JF
Zhang
Xiao-Ai
XA
Wu
Xiao-Ming
XM
Zhang
Wen-Yi
WY
Liu
Wei
W
Zuo
Shu-Qing
SQ
Cao
Zhi-Wei
ZW
Yang
Hong
H
Richardus
Jan H
JH
Habbema
J Dikf
JD
D041081:Anaplasma phagocytophilum / Q000235:genetics; D000818:Animals; D002681:China / Q000453:epidemiology; D016873:Ehrlichiosis / Q000453:epidemiology / Q000662:veterinary*; D015511:Goat Diseases / Q000453:epidemiology / Q000382:microbiology*; D006041:Goats; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012377:Rodentia; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology / Q000382:microbiology*