Quantum dots for multimodal molecular imaging of angiogenesis.
Quantum dots exhibit unique optical properties for bioimaging purposes. We have previously developed quantum dots with a paramagnetic and functionalized coating and have shown their potential for molecular imaging purposes. In the current mini-review we summarize the synthesis procedure, the in vitro testing and, importantly, the in vivo application for multimodal molecular imaging of tumor angiogenesis.
Mulder
Willem J M
WJ
Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1234, New York, NY 10029, USA. willem.mulder@mountsinai.org
Strijkers
Gustav J
GJ
Nicolay
Klaas
K
Griffioen
Arjan W
AW
D000818:Animals; D008823:Micelles; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000098:blood supply / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000175:diagnosis*; D045663:Quantum Dots
D008823:Micelles