[Dentification ability of inbred strain mice tooth germs homologically transplanted into oral submucosa].
OBJECTIVE
To establish a suitable environment for the bioengineered teeth in vivo by observing the dentification ability of BALB/C mice tooth germs homologically implanted into the oral submucosa.


METHODS
The first molar tooth germs of BALB/C mice 4 days after birth were transplanted into the oral submucosa of BALB/C male mice, and then recycled for regular histological observation after 1, 2, 3, and 6 week transplantation.


RESULTS
The tooth germs in the oral submucosa grew well with continuing developing enamelum and pulpodentinal complex, and the dentinal tubules were clear.


CONCLUSIONS
The environment of the BALB/C male mice oral submucosa is favorable for the growth of tooth germs in inbred strain BALB/C mice, and it can provide a new environment for the development of bioengineered teeth in vivo.
Li
Heng
H
Department of Stomatology, Xiangya Hospital, Central South University, Changsha 410008, China.
Que
Guoying
G
Zhang
Lei
L
D000818:Animals; D000831:Animals, Newborn; D003810:Dentinogenesis / Q000502:physiology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008963:Molar / Q000637:transplantation; D009061:Mouth Mucosa / Q000601:surgery*; D023822:Tissue Engineering; D014083:Tooth Germ / Q000637:transplantation*