title: Cross-sectional study of the prevalence of radiographic degenerative joint disease in domesticated cats.
abstract: OBJECTIVE
  To determine the prevalence of radiographic signs of degenerative joint disease (DJD) in a randomly selected sample of domestic cats.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Client-owned cats.
  
  
  METHODS
  Cats (n=100) from a single practice and equally distributed across 4 age groups (0-5; 5-10; 10-15, and 15-20 years old) were randomly selected (regardless of heath status) and sedated for orthogonal radiographic projections of all joints and the spine. Quasi-Poisson regression analysis was used to investigate the relationship between patient demographics, blood biochemistry, hematologic and urine analysis variables, and DJD severity.
  
  
  RESULTS
  Most (92%) cats had radiographic evidence of DJD; 91% had at least 1 site of appendicular DJD and 55% had > or = 1 site of axial column DJD. Affected joints in descending order of frequency were hip, stifle, tarsus, and elbow. The thoracic segment of the spine was more frequently affected than the lumbosacral segment. Although many variables were significantly associated with DJD, when variables were combined, only the association between age and DJD was significant (P<.0001). For each 1-year increase in cat age, the expected total DJD score increases by an estimated 13.6% (95% confidence interval: 10.6%, 16.8%).
  
  
  CONCLUSIONS
  Radiographically visible DJD is very common in domesticated cats, even in young animals and is strongly associated with age.
  
  
  CONCLUSIONS
  DJD is a common disease of domesticated cats that requires further investigation of its associated clinical signs.
authors.affiliation: Comparative Pain Research Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA. duncan_lascelles@ncsu.edu
authors.forename: B Duncan X
authors.initials: BD
authors.lastname: Lascelles
authors.forename: John B
authors.initials: JB
authors.lastname: Henry
authors.forename: James
authors.initials: J
authors.lastname: Brown
authors.forename: Ian
authors.initials: I
authors.lastname: Robertson
authors.forename: Andrea Thomson
authors.initials: AT
authors.lastname: Sumrell
authors.forename: Wendy
authors.initials: W
authors.lastname: Simpson
authors.forename: Simon
authors.initials: S
authors.lastname: Wheeler
authors.forename: Bernie D
authors.initials: BD
authors.lastname: Hansen
authors.forename: Helia
authors.initials: H
authors.lastname: Zamprogno
authors.forename: Mila
authors.initials: M
authors.lastname: Freire
authors.forename: Anthony
authors.initials: A
authors.lastname: Pease
mesh_terms: D000367:Age Factors; D000818:Animals; D002371:Cat Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology; D002415:Cats; D003430:Cross-Sectional Studies; D005260:Female; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D016012:Poisson Distribution; D015995:Prevalence; D011446:Prospective Studies; D011859:Radiography