Fulminant pancytopenia due to cytomegalovirus infection in an immunocompetent adult.
A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.
Koukoulaki
Maria
M
15th Department of Medicine, Division of Infectious Diseases, Evangelismos General Hospital, 45-47 Ipsilantou street, Athens, Greece. mkoukoulaki@gmail.com
Ifanti
Georgia
G
Grispou
Eirini
E
Papastamopoulos
Vassilios
V
Chroni
Georgia
G
Diamantopoulos
Emmanouil
E
Skoutelis
Athanasios
A
D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D018805:Sepsis / Q000209:etiology*; D012720:Severity of Illness Index
D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D011239:Prednisolone