Cellular therapy in 2010: focus on autoimmune and cardiac diseases.
Stem cell therapy has developed extensively in recent years, leading to several new clinical fields. The use of mesenchymal stromal cells sparks special interest, as it reveals the importance of the paracrine and immunomodulatory effects of these supporting cells, in disease and in cure. This review discusses our current understanding of the basic clinical principles of stem cell therapy and demonstrates the broad range of this treatment modality by examining two relatively new therapeutic niches--autoimmune and cardiac diseases.
Perl
Leor
L
Department of Medicine B, Meir Medical Center, Kfar Saba, Israel.
Weissler
Adaya
A
Mekori
Yoseph A
YA
Mor
Adam
A
D001327:Autoimmune Diseases / Q000628:therapy*; D006331:Heart Diseases / Q000628:therapy*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D009203:Myocardial Infarction / Q000628:therapy