A case of isolated plexiform neurofibroma in a patient with myasthenia gravis.
We report a case of an isolated plexiform neurofibroma occurring in a patient with myasthenia gravis. A 48-year-old man presented with asymptomatic skin-colored nodules on the tip of his 4th finger. Microscopically, a plexiform neurofibroma was identified located in the dermis that appeared to originate from small superficial nerves. He had a 20-year history of treated myasthenia gravis; otherwise, his personal and family histories were unremarkable. Given that myasthenia gravis is a disorder of the peripheral nerves, plexiform neurofibromas could be associated with myasthenia gravis. However, the development of an isolated plexiform neurofibroma in a case of myasthenia gravis has not yet been reported. The occurrence of a neurofibromas in a patient with myasthenia gravis suggests a link in the pathogenesis of these two diseases.
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Seung Ju
SJ
Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea.
Kim
Dae Hun
DH
Kim
Nari
N
Lee
Young
Y
Seo
Young Joon
YJ
Park
Jang Kyu
JK
Lee
Jeung Hoon
JH