title: Trimethoprim-sulfamethoxazole-induced rhabdomyolysis in an allogeneic stem cell transplant patient.
abstract: Trimethoprim-Rhabdomyolysis is a serious, potentially life-threatening complication diagnosed when creatine phosphokinase levels exceed 1000 U/L. Although many drugs are associated with rhabdomyolysis, the previous reports of trimethoprim-sulfamethoxazole (TMP/SMX)-induced rhabdomyolysis have involved patients with human immunodeficiency virus/acquired immunodeficiency syndrome. This is the first report, to our knowledge, of TMP/SMX-induced rhabdomyolysis in an allogeneic stem cell transplant patient.
authors.affiliation: Simon Cancer Center-Clarian Health, Indiana University, Indianapolis, Indiana, USA. pkiel@clarian.org
authors.forename: P J
authors.initials: PJ
authors.lastname: Kiel
authors.forename: N
authors.initials: N
authors.lastname: Dickmeyer
authors.forename: J E
authors.initials: JE
authors.lastname: Schwartz
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects*; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D014184:Transplantation, Homologous; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D003402:Creatine Kinase