title: The relationships between leptin and measures of fitness and fatness are dependent upon obesity status in youth.
abstract: The relationship between peak aerobic fitness (peakVO2) and plasma leptin was assessed in 25 normal (BMI < 85th %tile) and 25 overweight (BMI > 85th %tile) youth, ages 7-17 years. In the overall analysis peakVO2 was related to leptin when expressed in mL/kg/min (R2 = .516, p < .0001), or as ml/kg(FFM)/min (R2 = .127, p = .01). The relationships between peak VO2 and leptin were no longer significant when percent bodyfat was added to the models. In subanalyses by weight groups, peak VO2: leptin relationships were not evident for normal weight, but remained for overweight youth. In conclusion the relationship between aerobic fitness and leptin in youth is dependent upon weight status.
authors.affiliation: Dept. of EXSS, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-8700, USA.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Hosick
authors.forename: Robert G
authors.initials: RG
authors.lastname: McMurray
authors.forename: Dan M
authors.initials: DM
authors.lastname: Cooper
mesh_terms: D000293:Adolescent; D050218:Body Fat Distribution; D015992:Body Mass Index; D002648:Child; D005080:Exercise Test; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D050177:Overweight / Q000097:blood* / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000502:physiology*; D010809:Physical Fitness / Q000502:physiology*; D012044:Regression Analysis
chemical_list: D020738:Leptin