Relationship between prostate-specific antigen and body mass index according to age: lower prostate-specific antigen in middle-aged overweight and obese Korean men.
OBJECTIVE
To analyze the relationship between serum prostate-specific antigen (PSA) and body mass index (BMI) according to age in a population of ostensibly healthy Korean men.


METHODS
Between 2002 and 2006, data from 13,025 men who visited health promotion centers were evaluated. All men underwent anthropometric measurements and serum PSA determination. The relationship between serum PSA and BMI according to age was analyzed.


RESULTS
The median age was 50.0 years and the median serum PSA level was 0.69 ng/ml. There was no relationship between serum PSA and BMI in the group whose BMI was <23 kg/m(2). The serum PSA showed a significant inverse relationship in those with BMI of ≥23 kg/m(2). However, this finding was only true among 40- to 59-year-old middle aged men and no such relationship between serum PSA and BMI was seen in the older groups (60-79 years of age).


CONCLUSIONS
Our study revealed serum PSA had a significant inverse relationship with BMI in overweight and obese men aged between 40 and 59 years; however, there was no relationship between serum PSA and BMI in men whose age was older than 60 years.
Yang
Won Jae
WJ
Department of Urology, College of Medicine, Soonchunhyang University, Seoul, Korea.
Cheon
Sang Hyeon
SH
Kim
Young Sig
YS
Kim
Dong Jun
DJ
Seong
Do Hwan
do H
Song
Yun Seob
YS
Cho
Soung Yong
SY
Cho
In Rae
IR
Kim
Sun Il
SI
Kim
Se Joong
SJ
Kim
Chun Il
CI
Choi
Young Deuk
YD
Hong
Sung Joon
SJ
Im
Hyoungjune
H
Cho
Jin Seon
JS
D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D044466:Asian People; D015992:Body Mass Index; D015536:Down-Regulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000208:ethnology*; D050177:Overweight / Q000097:blood* / Q000208:ethnology*; D017430:Prostate-Specific Antigen / Q000097:blood*; D056910:Republic of Korea
D017430:Prostate-Specific Antigen