title: Concomitant pulmonary infection with Nocardia transvalensis and Aspergillus ustus in lung transplantation.
abstract: Lung infections with Nocardia and Aspergillus spp in lung transplant recipients (LTRs) create diagnostic and therapeutic challenges. The present case illustrates the difficulties in identifying these pathogens in LTRs. A high degree of clinical suspicion and aggressive early management are required to ensure good outcomes. Although prospective data on treating these conditions are scarce, the empiric use of combination broad-spectrum anti-microbials initially seems prudent.
authors.affiliation: Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-0772, USA.
authors.forename: Miguel M
authors.initials: MM
authors.lastname: Cabada
authors.forename: Shawn P
authors.initials: SP
authors.lastname: Nishi
authors.forename: Alfred S
authors.initials: AS
authors.lastname: Lea
authors.forename: Vicki
authors.initials: V
authors.lastname: Schnadig
authors.forename: Gisele A
authors.initials: GA
authors.lastname: Lombard
authors.forename: Scott D
authors.initials: SD
authors.lastname: Lick
authors.forename: Vincent G
authors.initials: VG
authors.lastname: Valentine
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001230:Aspergillus; D015897:Comorbidity; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000276:immunology / Q000601:surgery*; D007165:Immunosuppression Therapy; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016040:Lung Transplantation / Q000276:immunology; D008297:Male; D009615:Nocardia; D009617:Nocardia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D055732:Pulmonary Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents