[Prediction of the GVHD after allo-HSCT by sequence similar matching method].
This study was aimed to investigate the role of sequence similar matching (SSM) method in prediction of GVHD after HLA unmatched allogeneic hematopoietic stem cell transplantation (allo-HSCT). The data from 23 patients undergoing HLA unmatched allo-HSCT were analyzed and calculated by SSM method. The results showed that the incidence of acute and severe GVHD were significantly less in the allo-HSCT cases with total SSM value less than 55. In conclusion, the SSM method can be used to predict GVHD in the HLA-unmatched allogeneic hematopoietic stem cell transplantation.
Zhao
Dan-Dan
DD
Department of Hematology, 304th Clinical Division, Chinese PLA General Hospital, Beijing 100048 China.
Liu
Zhou-Yang
ZY
Cao
Yong-Bin
YB
Jiang
Shuang
S
DA
Wan-Ming
WM
Wu
Xiao-Xiong
XX
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006086:Graft vs Host Disease / Q000175:diagnosis* / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects* / Q000379:methods; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous / Q000009:adverse effects; D055815:Young Adult