title: [Blastomycosis: report of an imported case in Mexico, with only cutaneous lesions].
abstract: BACKGROUND
  Blastomycosis is a granulomatous infectious disease. It is caused by the dimorphus fungus Blastomyces dermatitidis. It predominates in the United States of America, but in Mexico two systemic imported cases have been reported. Cutaneous primary blastomycosis is a rare clinical presentation, which occurs after traumatic inoculation of the fungus.
  
  
  OBJECTIVE
  We present a case of a 54 year old male, born in Guadalajara, Mexico, and living in Chicago, USA, who had two verrucous nodules (8mm in diameter) on the forehead and right nasogenian fold, of 4 weeks progression.
  
  
  METHODS
  We made a histopathological study (hematoxylin and eosin, Gomori Groccot and periodic acid-Schiff stains) and mycology studies (direct microscopic examination, Sabouraud and mycobiotic agar cultures). Multiple studies were made with no evidence of systemic spread.
  
  
  RESULTS
  Biopsy showed a dermal inflammatory infiltrate made up of lymphocytes, neutrophils, histiocytes and multinucleated giant cells. A few large, haloed, broad-based budding yeasts were also observed. Direct examination with KOH revealed broad-based budding yeasts, 10μm in diameter. Culture at 35°C yielded a white, pleated colony, which changed into a yellowish cerebriform. Multiple studies were made with no evidence of systemic spread. Itraconazole 200mg qd PO was given over a 2 month period, with a complete clinical and mycological response.
  
  
  CONCLUSIONS
  This is the first imported case in Mexico of blastomycosis with cutaneous lesions without systemic involvement.
authors.affiliation: Centro de Referencia en Micología Médica (CEREMI), Instituto Dermatológico de Jalisco Dr. José Barba Rubio, Zapopan, Jalisco, México.
authors.forename: Adriana
authors.initials: A
authors.lastname: Rodríguez-Mena
authors.forename: Jorge
authors.initials: J
authors.lastname: Mayorga
authors.forename: Guillermo
authors.initials: G
authors.lastname: Solís-Ledesma
authors.forename: José
authors.initials: J
authors.lastname: Barba-Gómez
mesh_terms: D001759:Blastomycosis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D014195:Travel; D014481:United States