title: Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement.
abstract: Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is an uncommon infection for which there is no optimal therapy. We describe a young, female patient who presented with extensive cutaneous and neurological involvement and who recovered after receiving prolonged treatment with miltefosine, fluconazole, and albendazole.
authors.affiliation: Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru. dalmaext@gmail.com
authors.forename: Dalila Y
authors.initials: DY
authors.lastname: Martínez
authors.forename: Carlos
authors.initials: C
authors.lastname: Seas
authors.forename: Francisco
authors.initials: F
authors.lastname: Bravo
authors.forename: Pedro
authors.initials: P
authors.lastname: Legua
authors.forename: Cesar
authors.initials: C
authors.lastname: Ramos
authors.forename: Alfonso M
authors.initials: AM
authors.lastname: Cabello
authors.forename: Eduardo
authors.initials: E
authors.lastname: Gotuzzo
mesh_terms: D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000562:Amebiasis / Q000188:drug therapy* / Q000469:parasitology* / Q000473:pathology; D056894:Amoebozoa / Q000145:classification / Q000302:isolation & purification*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D004660:Encephalitis / Q000188:drug therapy* / Q000469:parasitology; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006651:Histocytochemistry; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010767:Phosphorylcholine / Q000031:analogs & derivatives / Q000627:therapeutic use; D011859:Radiography; D012876:Skin Diseases, Parasitic / Q000188:drug therapy* / Q000469:parasitology / Q000473:pathology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000981:Antiprotozoal Agents; D010767:Phosphorylcholine; C039128:miltefosine; D015725:Fluconazole; D015766:Albendazole