Synthesis, characterisation and antibacterial activity of PVA/TEOS/Ag-Np hybrid thin films.
Novel hybrid material thin films based on polyvinyl alcohol (PVA)/tetraethyl orthosilicate (TEOS) with embedded silver nanoparticles (AgNps) were synthesized using sol-gel method. Two different strategies for the synthesis of silver nanoparticles in PVA/TEOS matrix were applied based on reduction of the silver ions by thermal annealing of the films or by preliminary preparation of silver nanoparticles using PVA as a reducing agent. The successful incorporation of silver nanoparticles ranging from 5 to 7nm in PVA/TEOS matrix was confirmed by TEM and EDX analysis, UV-Vis spectroscopy and XRD analysis. The antibacterial activity of the synthesized hybrid materials against etalon strains of three different groups of bacteria -Staphylococcus aureus (gram-positive bacteria), Escherichia coli (gram-negative bacteria), Pseudomonas aeruginosa (non-ferment gram-negative bacteria) has been studied as they are commonly found in hospital environment. The hybrid materials showed a strong bactericidal effect against E. coli, S. aureus and P. aeruginosa and therefore have potential applications in biotechnology and biomedical science.
Bryaskova
Rayna
R
University of Chemical Technology and Metallurgy, Department of Polymer Engineering, 8 Kl. Ohridski, 1756 Sofia, Bulgaria.
Pencheva
Daniela
D
Kale
Girish M
GM
Lad
Umesh
U
Kantardjiev
T
T
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D011142:Polyvinyl Alcohol / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012821:Silanes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D012821:Silanes; D012834:Silver; C040733:tetraethoxysilane; D011142:Polyvinyl Alcohol