title: Risk of postoperative hypoxemia in ambulatory orthopedic surgery patients with diagnosis of obstructive sleep apnea: a retrospective observational study.
abstract: BACKGROUND
  It is unclear when it is safe to discharge patients with a diagnosis of Obstructive Sleep Apnea (OSA) after ambulatory surgical procedures due to concern for postoperative respiratory compromise and hypoxemia. Our OSA patients undergoing ambulatory-type orthopedic procedures are monitored overnight in the PACU, thus we reviewed patient records to determine incidence of complications.
  
  
  METHODS
  Two hundred and six charts of patients with preoperative diagnosis of OSA based on ICD-9 codes were reviewed for outcomes including episodes of hypoxemia. Univariate analysis followed by logistic regression and propensity analysis was performed to determine independent risk factors for hypoxemia and association with adverse outcomes.
  
  
  RESULTS
  The majority of patients had regional anesthesia (95%). Thirty four percent of patients had hypoxemia in the PACU. Initial risk factors for hypoxemia identified by univariate analysis were BMI >/= 35, increased age, history of COPD, upper extremity procedure, and use of peripheral nerve block. Independent risk factors identified by logistic regression were history of COPD (OR 3.64 with 95% CI 1.03-12.88) and upper extremity procedure (2.53, 1.36-4.68). After adjustment with propensity scores, adverse events were rare, and unplanned hospital admission after PACU stay was not increased with hypoxemia (11% vs 16%)
  
  
  CONCLUSIONS
  Episodes of postoperative hypoxemia in OSA patients undergoing ambulatory surgery with regional anesthesia are not associated with increased adverse outcomes or unplanned hospital admission.
authors.affiliation: Department of *Anesthesiology, Hospital for Special Surgery, Weill College of Medicine of Cornell University, 535 East 70th Street, New York, NY 10021, USA. liusp@hss.edu.
authors.forename: Spencer S
authors.initials: SS
authors.lastname: Liu
authors.forename: Mary F
authors.initials: MF
authors.lastname: Chisholm
authors.forename: Raymond S
authors.initials: RS
authors.lastname: John
authors.forename: Justin
authors.initials: J
authors.lastname: Ngeow
authors.forename: Yan
authors.initials: Y
authors.lastname: Ma
authors.forename: Stavros G
authors.initials: SG
authors.lastname: Memtsoudis