Campylobacter jejuni and Campylobacter coli in children from communities in Northeastern Brazil: molecular detection and relation to nutritional status.
This study determined the prevalence of Campylobacter jejuni/coli and its relation with nutritional status in children from Northeastern Brazil. This was a case-control study design. Stool samples were evaluated for hipO (C. jejuni), ask (C. coli), and cdtABC (C. jejuni's cytolethal distending toxin) genes. The nutritional status from these children was assessed by anthropometric measures and z-scores. C. jejuni and C. coli were detected in 9.6% (8/83) and 6.0% (5/83) in the diarrhea group and in 7.2% (6/83) and 1.2% (1/83) of the nondiarrhea group, respectively. Children with positive molecular detection of C. jejuni showed significantly lower z-scores than children without C. jejuni. The cdtABC operon was found in 57% of hipO(+) samples. C. jejuni/coli prevalence was similar in diarrhea and nondiarrhea groups. There was a significant association of C. jejuni infection with lower nutritional status.
da Silva Quetz
Josiane
J
Institute of Biomedicine for Brazilian Semi-Arid and Clinical Research Unit/Center for Global Health, Federal University of Ceara, Fortaleza, Brazil. jquetz@gmail.com
Lima
Ila Fernanda Nunes
IF
Havt
Alexandre
A
de Carvalho
Eunice Bobo
EB
Lima
Noélia Leal
NL
Soares
Alberto Melo
AM
Mota
Rosa Maria Salani
RM
Guerrant
Richard Littleton
RL
Lima
Aldo Angelo Moreira
AA
D000886:Anthropometry / Q000379:methods; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics; D001938:Brazil; D002169:Campylobacter Infections / Q000453:epidemiology* / Q000382:microbiology; D017000:Campylobacter coli / Q000302:isolation & purification*; D016123:Campylobacter jejuni / Q000302:isolation & purification*; D016022:Case-Control Studies; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009752:Nutritional Status; D015995:Prevalence
D001426:Bacterial Proteins; D001427:Bacterial Toxins