title: Electroconvulsive therapy and corpus callosum aplasia: a case report.
abstract: The use of electroconvulsive therapy (ECT) in mental retardation has been discussed in several case reports and case series. In this case, a 35-year-old patient with corpus callosum aplasia and severe therapy-resistant catatonia was treated with a series of unilateral ECT and improved considerably. Electroencephalographic recordings during ECT showed a complete interhemispheric synchronicity due to regular anterior and posterior commissural fibers. After ECT, the patient received long-term medication with quetiapine and lorazepam. Electroconvulsive therapy turned out to be a powerful tool for treating catatonic syndromes in patients with mental retardation and should be considered as a potent treatment option in otherwise therapy-resistant cases.
authors.affiliation: Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Munich, Germany. ulrich.palm@med.uni-muenchen.de
authors.forename: Ulrich
authors.initials: U
authors.lastname: Palm
authors.forename: Anna
authors.initials: A
authors.lastname: Forsthoff
authors.forename: Larissa
authors.initials: L
authors.lastname: de la Fontaine
authors.forename: Tobias
authors.initials: T
authors.lastname: Rupprecht
authors.forename: Susanne
authors.initials: S
authors.lastname: Karch
authors.forename: Eva M
authors.initials: EM
authors.lastname: Meisenzahl
authors.forename: Oliver
authors.initials: O
authors.lastname: Pogarell
mesh_terms: D000328:Adult; D061085:Agenesis of Corpus Callosum; D002389:Catatonia / Q000150:complications* / Q000628:therapy*; D004565:Electroconvulsive Therapy; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D008297:Male