title: [Effects of chronic exposure of power frequency magnetic field on neurobehavior in rats].
abstract: OBJECTIVE
  To observe the effect of chronic exposure to extremely low frequency magnetic field on neurobehavioral of adult rats.
  
  
  METHODS
  Fifty Hz sinusoidal extremely low frequency magnetic field (ELF-MF) was used in this experimental procedure and the strength of magnetic field was fixed at 2 mT. Thirty male adult rats were divided randomly into 3 groups: (1) no ELF MF exposure (control group, n=10); (2) exposure to ELF MF 1 h/day (MF1h group, n=10); (3) exposure to ELF MF 4 h/day (MF4h group, n=10). The neurobehavioral changes of rats were detected by the open field test, elevated plus maze test and light/dark box test.
  
  
  RESULTS
  Compared with controls, no significant difference was found in rats of MF1h group in any test. Rats in MF4h group showed increased thigmotaxis, more grooming in the open field test; less time spent in open arms, central part and more time spent in closed arms. However, no significant difference was observed in the light/dark test in MF1h or MF4h group.
  
  
  CONCLUSIONS
  Chronic ELF MF exposure has an anxiogenic effect on rats, which is dependent on the daily exposure duration.
authors.affiliation: Department of Occupational & Environmental Health, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Tong-tong
authors.initials: TT
authors.lastname: Liu
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.forename: Li-hua
authors.initials: LH
authors.lastname: He
authors.forename: Kang-ping
authors.initials: KP
authors.lastname: Ye
authors.forename: Ying-chun
authors.initials: YC
authors.lastname: Xu
authors.forename: Fei-ruo
authors.initials: FR
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001008:Anxiety Disorders / Q000209:etiology* / Q000503:physiopathology; D001522:Behavior, Animal / Q000502:physiology / Q000528:radiation effects*; D001921:Brain / Q000503:physiopathology / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure; D008297:Male; D009043:Motor Activity / Q000502:physiology / Q000528:radiation effects; D011597:Psychomotor Performance / Q000528:radiation effects; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley