[Peptic ulcer: facts and questions -- 2010].
Etiology and clinical manifestation of the peptic ulcer keep changes nowadays. Helicobacter pylori-infection, nonsteroidal anti-inflammatory drugs and small dosage acetic acid treatment are the main etiological factors. Helicobacter pylori positive peptic ulcer can be treated with eradication of the bacterium. Prevention of the NSAID-ulcer and the prescription of the acid suppressive therapy depend on the gastrointestinal and cardiovascular risk factors of patient. Despite of the effective therapies, there are still questions to answer. The number of Helicobacter pylori and NSAID negative ulcers is likely to increase, their therapy must be clarified. There's a fall in the eradication rate of Helicobacter pylori infection, the optimal treatment is missing.
Hagymási
Krisztina
K
Semmelweis Egyetem, Altalános Orvostudományi Kar II. Belgyógyászati Klinika, Budapest. hagymasikriszti@freemail.hu
Tulassay
Zsolt
Z
D000863:Antacids / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D015994:Incidence; D010437:Peptic Ulcer / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000517:prevention & control* / Q000523:psychology; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications
D000863:Antacids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D054328:Proton Pump Inhibitors