title: Method for regio-, chemo- and stereoselective deuterium labeling of sugars based on ruthenium-catalyzed C-H bond activation.
abstract: An efficient and facile deuterium labeling of sugars has been achieved in a completely regio-, chemo- and stereoselective manner using the Ru/C-H(2)-D(2)O combination via C-H bond activation assisted by the coordination of Ru to the oxygen atom of the sugar-hydroxyl groups.
authors.affiliation: Laboratory of Organic Chemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Iwata
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Sawama
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Monguchi
authors.forename: Hironao
authors.initials: H
authors.lastname: Sajiki
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003903:Deuterium / Q000737:chemistry*; D041961:Deuterium Exchange Measurement; D006859:Hydrogen / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D002241:Carbohydrates; D002244:Carbon; D012428:Ruthenium; D006859:Hydrogen; D003903:Deuterium; D010100:Oxygen