Siloxy(trialkoxy)ethene undergoes regioselective [2+2] cycloaddition to ynones and ynoates en route to functionalized cyclobutenediones.
Regioselective [2+2] cycloaddition of ynones or ynoates to siloxy(trialkoxy)ethene (KSA) is described. A siloxy group on the KSA directs the perfect regioselectivity, allowing rapid construction of various functionalized cyclobutenedione derivatives.
Iwata
Shin
S
Department of Chemistry, Tokyo Institute of Technology, and SORST, JST Agency, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
Hamura
Toshiyuki
T
Suzuki
Keisuke
K
D003500:Cyclization; D003503:Cyclobutanes / Q000737:chemistry*; D005030:Ethylenes / Q000737:chemistry*; D015394:Molecular Structure; D012833:Siloxanes / Q000737:chemistry*
D003503:Cyclobutanes; D005030:Ethylenes; D012833:Siloxanes; C036216:ethylene