[Research progress on autophagy in hematopoietic malignancies].
Autophagy is a process of bulk degradation of proteins and organelles in cytoplasm.Autophagy has many normal physiological functions in cellular catabolism; therefore is essential for cell homeostasis. In some circumstances autophagy can induces cell death, namely autophagic cell death. Recent studies have suggested that autophagy plays an important role in both normal tissue development and a variety of diseases, including cancer. Therefore, the strategy targeting autophagy pathway may represent a new way of cancer treatment.
Tong
Yin
Y
The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Li
Lu
L
Liu
Hui
H
Qian
Wen-bin
WB
D017209:Apoptosis / Q000502:physiology; D001343:Autophagy / Q000502:physiology*; D016923:Cell Death / Q000502:physiology*; D019337:Hematologic Neoplasms / Q000473:pathology* / Q000503:physiopathology; D015398:Signal Transduction