title: [Electrophysiological evaluation of the hearing function following cisplatin administration].
abstract: Experiments on guinea pigs with the use of electrophysiological methods (short-latency auditory evoked potentials, SLAEPs, and distortion product otoacoustic emission, DPOAE) have demonstrated damage of outer hair cells following application of therapeutic doses of cisplatin. It is concluded that finding of the logarithmic amplitude-time dependence for the first SLAEPs peak permits to diagnose an injury to outer hair cells.
authors.forename: M R
authors.initials: MR
authors.lastname: Bogomol'skiĭ
authors.forename: I N
authors.initials: IN
authors.lastname: D'iakonova
authors.forename: I V
authors.initials: IV
authors.lastname: Rakhmanova
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Sapozhnikov
authors.forename: O R
authors.initials: OR
authors.lastname: Stakhovskaia
authors.forename: A M
authors.initials: AM
authors.lastname: Tikhomirov
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects*; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000473:pathology; D006309:Hearing / Q000187:drug effects* / Q000502:physiology; D034381:Hearing Loss / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin