title: Evaluation of the vascular anatomy in potential living kidney donors with gadolinium-enhanced magnetic resonance angiography: comparison with digital subtraction angiography and intraoperative findings.
abstract: BACKGROUND
  X-ray contrast arteriography has traditionally been used for pre-operative evaluation in living kidney donors. However, magnetic resonance angiography (MRA) offers a non-invasive alternative, which has been considered to be less accurate. This study was performed to determine whether MRA in the pre-operative investigation of living kidney donors provides sufficient information.
  
  
  METHODS
  From December 2005 to December 2007, 173 potential live donors were evaluated in this study. Donors performed digital subtraction angiography (DSA) and those with one or more accessory arteries at least on one side recruited for further evaluation with three-dimensional gadolinium-enhanced MRA.
  
  
  RESULTS
  A total of 30 donors constituted the study population. When compared with DSA as the reference method, MRA detected 20 of 36 renal accessory arteries which indicates a sensitivity of 55.6%. The difference between MRA and DSA in identifying accessory renal arteries was significant (p-value <0.001). Considering intraoperative findings as the standard of reference, MRA depicted correctly four of six (66.7%) accessory arteries on the transplanted kidneys.
  
  
  CONCLUSIONS
  MRA has the advantage of avoiding exposure to ionizing radiation and is non-invasive. These are important considerations in pre-operative evaluation of a generally healthy donor population. However, MRA provides suboptimal accuracy in detecting small accessory arteries.
authors.affiliation: Urology and Nephrology Research Center, Shahid Modarress Hospital, Tehran, Iran.
authors.forename: Majid A
authors.initials: MA
authors.lastname: Asgari
authors.forename: Farid
authors.initials: F
authors.lastname: Dadkhah
authors.forename: Ali R
authors.initials: AR
authors.lastname: Ghadian
authors.forename: Mohammad R
authors.initials: MR
authors.lastname: Razzaghi
authors.forename: Mohammad H
authors.initials: MH
authors.lastname: Noorbala
authors.forename: Erfan
authors.initials: E
authors.lastname: Amini
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007668:Kidney / Q000033:anatomy & histology* / Q000098:blood supply*; D016030:Kidney Transplantation; D019520:Living Donors; D018810:Magnetic Resonance Angiography; D008297:Male; D011300:Preoperative Care; D011379:Prognosis; D055815:Young Adult
chemical_list: D003287:Contrast Media; D005682:Gadolinium