[Effects of chronic exposure of power frequency magnetic field on neurobehavior in rats].
OBJECTIVE
To observe the effect of chronic exposure to extremely low frequency magnetic field on neurobehavioral of adult rats.


METHODS
Fifty Hz sinusoidal extremely low frequency magnetic field (ELF-MF) was used in this experimental procedure and the strength of magnetic field was fixed at 2 mT. Thirty male adult rats were divided randomly into 3 groups: (1) no ELF MF exposure (control group, n=10); (2) exposure to ELF MF 1 h/day (MF1h group, n=10); (3) exposure to ELF MF 4 h/day (MF4h group, n=10). The neurobehavioral changes of rats were detected by the open field test, elevated plus maze test and light/dark box test.


RESULTS
Compared with controls, no significant difference was found in rats of MF1h group in any test. Rats in MF4h group showed increased thigmotaxis, more grooming in the open field test; less time spent in open arms, central part and more time spent in closed arms. However, no significant difference was observed in the light/dark test in MF1h or MF4h group.


CONCLUSIONS
Chronic ELF MF exposure has an anxiogenic effect on rats, which is dependent on the daily exposure duration.
Liu
Tong-tong
TT
Department of Occupational & Environmental Health, Peking University School of Public Health, Beijing 100191, China.
Wang
Sheng
S
He
Li-hua
LH
Ye
Kang-ping
KP
Xu
Ying-chun
YC
Zhang
Fei-ruo
FR
D000818:Animals; D001008:Anxiety Disorders / Q000209:etiology* / Q000503:physiopathology; D001522:Behavior, Animal / Q000502:physiology / Q000528:radiation effects*; D001921:Brain / Q000503:physiopathology / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure; D008297:Male; D009043:Motor Activity / Q000502:physiology / Q000528:radiation effects; D011597:Psychomotor Performance / Q000528:radiation effects; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley