[Drug eruption during living-donor renal transplantation in which it was difficult to identify the causative drug: a case report].
A 59-year-old man with renal failure given oral medication for the symptoms associated with it had no drug allergies before surgery. The patient received 8 units of FFP for a surgery of gastric tumor. The stomach tumor was benign, and living-donor renal transplantation was performed. After the living-donor transplantation, extensive reddening and swelling were observed over the patient's entire body. Anaphylaxis due to drug allergy was considered, and the patient's course was monitored. The flare and swelling tended to regress, and after about 3 hours they were resolved. The following day the drugs used intraoperatively were tested, but it was difficult to identify any allergy-inducing drugs. Ultimately, the FFP was suspected as the cause, and the patient appeared to have been saved by the methylprednisolone used as an immunosuppressive agent.
Hashimoto
Kazuyoshi
K
Department of Anethesiology, Uwajima Tokusyukai General Hospital, Uwajima 798-0003.
Ozawa
Yoshiki
Y
Tsurutani
Ai
A
Kobayashi
Tomoharu
T
Kojima
Keimei
K
Mannami
Makoto
M
D003875:Drug Eruptions / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D010949:Plasma
D007166:Immunosuppressive Agents; D008775:Methylprednisolone