Proarrhythmia Induced by Propafenone: What is the Mechanism?
Propafenone, a Class IC antiarrhythmic drug, is an orally active sodium channel-blocking agent. It is effective in supraventricular tachyarrhythmias and is particularly useful in converting atrial fibrillation to sinus rhythm. In therapeutic doses, it may cause non-cardiac and cardiac toxicity, including proarrhythmia.
Femenia
Francisco
F
Unidad de Arritmias, Departamento de Cardiología, Hospital Espanol de Mendoza, Argentina.
Palazzolo
Jorge
J
Arce
Mauricio
M
Arrieta
Martin
M