Nonalcoholic fatty liver disease as a comorbidity of childhood obesity.
Childhood obesity is a worldwide health problem associated with an increase in the prevalence and severity of comorbid conditions including nonalcoholic fatty liver disease (NAFLD). The increasing number of children with NAFLD presents a major public health concern. This review focuses on the recent advancements in the understanding of the epidemiology, diagnosis, histology, pathogenesis and treatment of pediatric NAFLD and highlights ongoing challenges and unmet needs in the area.
Barshop
Nicole J
NJ
Department of Pediatrics, University of California, San Diego, California, CA 92103, USA, Tel.: +1 619 543 7544, , nbarshop@ucsd.edu.
Francis
Cameron S
CS
Schwimmer
Jeffrey B
JB
Lavine
Joel E
JE