title: Copper-catalyzed alkynylation of amides with potassium alkynyltrifluoroborates: a room-temperature, base-free synthesis of ynamides.
abstract: An efficient copper-mediated method for the coupling of potassium alkynyltrifluoroborates with nitrogen nucleophiles is reported. This reaction provides the first base-free and room-temperature synthesis of ynamides and allows for an easy preparation of these useful building blocks.
authors.affiliation: Institut Lavoisier de Versailles, UMR CNRS 8180, Université de Versailles Saint-Quentin en Yvelines, 45, avenue des Etats-Unis, 78035 Versailles Cedex, France.
authors.forename: Kévin
authors.initials: K
authors.lastname: Jouvin
authors.forename: François
authors.initials: F
authors.lastname: Couty
authors.forename: Gwilherm
authors.initials: G
authors.lastname: Evano