Muir-Torre syndrome: Facts and controversies.
The cutaneous presentation of a tumor sometimes has implications for a patient and his or her family, and Muir-Torre syndrome is an example of this. Because a single skin lesion can have broad consequences, it is important for clinicians to be aware of Muir-Torre syndrome. The definition, potential clues, the role of ancillary testing (microsatellite, immunohistochemical, and genetic), and screening recommendations are reviewed.
Ko
Christine J
CJ
Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA. christine.ko@yale.edu
D055088:Early Detection of Cancer / Q000379:methods; D005820:Genetic Testing; D006801:Humans; D007150:Immunohistochemistry; D053842:Microsatellite Instability; D055653:Muir-Torre Syndrome / Q000175:diagnosis* / Q000235:genetics; D017410:Practice Guidelines as Topic; D012307:Risk Factors