title: Metrics of the normal cornea: anterior segment imaging with the Visante OCT.
abstract: OBJECTIVE
  The purpose of the study was to obtain anterior segment biometry for 40 normal eyes and to measure variables that may be useful to design large diameter gas permeable contact lenses that sit outside the region normally viewed by corneal topographers. Also, the distribution of these variables in the normal eye and how well they correlated to each other were determined.
  
  
  METHODS
  This is a cross-sectional study, in which data were collected at a single study visit. Corneal topography and imaging of the anterior segment of the eye were performed using the Orbscan II and Visante OCT. The variables that were collected were horizontal K reading, central corneal/scleral sagittal depth at 15 mm chord, and nasal and temporal angles at the 15 mm chord using the built-in software measurement tools.
  
  
  RESULTS
  The central horizontal K readings for the 40 eyes were 43 +/- 1.73 D (7.85 +/- 0.31 mm), with +/- 95% confidence interval (CI) of 38.7 (8.7 mm) and 46.6 D (7.24 mm). The mean corneal/scleral sagittal depth at the 15 mm chord was 3.74 +/- 0.19 mm and the range was 3.14 to 4.04 mm. The average nasal angle (which was not different from the temporal angle) at the 15 mm chord was 39.32 +/- 3.07 degrees and the +/- 95%CI was 33.7 and 45.5 degrees. The correlation coefficient comparing the K reading and the corneal/scleral sagittal depth showed the best correlation (0.58, p < 0.001). The corneal/scleral sagittal depth at 15 mm correlated less with the nasal angle (0.44, p = 0.004) and the weakest correlation was for the nasal angle at 15 mm with the horizontal readings (0.32, p = 0.046).
  
  
  CONCLUSIONS
  The Visante OCT is a valuable tool for imaging the anterior segment of the eye. The Visante OCT is especially effective in providing the biometry of the peripheral cornea and sclera and may help in fitting GP lenses with a higher percentage of initial lens success, when the corneal sag and lens sag are better matched.
authors.affiliation: Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada. gsorbara@sciborg.uwaterloo.ca
authors.forename: Luigina
authors.initials: L
authors.lastname: Sorbara
authors.forename: Jyotsna
authors.initials: J
authors.lastname: Maram
authors.forename: Desmond
authors.initials: D
authors.lastname: Fonn
authors.forename: Craig
authors.initials: C
authors.lastname: Woods
authors.forename: Trefford
authors.initials: T
authors.lastname: Simpson
mesh_terms: D000328:Adult; D003261:Contact Lenses; D019781:Corneal Topography / Q000295:instrumentation*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D012984:Software; D041623:Tomography, Optical Coherence / Q000295:instrumentation*