title: [Subarachnoid blockade with ropivacaine versus bupivacaine in urologic and orthopedic surgery].
abstract: OBJECTIVE
  To compare the effects of intrathecal isobaric ropivacaine (IR) versus isobaric bupivacaine (IB) in a dose ratio of 3:2 in non-ambulatory urologic and orthopedic surgery.
  
  
  METHODS
  One hundred and seventeen patients scheduled for surgery were randomized and assigned in a double-blind fashion to receive either 15 mg of IR (n = 58) or 10 mg of IB (n = 59) into the subarachnoid space.
  
  
  RESULTS
  There were no differences about age, sex distribution, body mass index, type of surgical interventions and operative time. Both groups were similar respect to latency time and extension of sensory block. Complete motor blockade was reached in more than 90 % of patients of both groups ten minutes after the intrathecal injection and the length was significantly longer in the IB group (226.4 +/- 22.3 minutes versus 266.5 +/- 29.5, p < 0.001). There was no significant hypotension or bradicardia during the transoperative period. Three and a half hours after the end of the surgery, more patients of the IB group required intravenous analgesics and opiaceous derivates (p < 0.001).
  
  
  CONCLUSIONS
  The motor blockade was longer in the IB group but postoperative analgesia was better in the IR group.
authors.affiliation: Departamento de Anestesiología, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.
authors.forename: Oscar
authors.initials: O
authors.lastname: Hinojosa-Sánchez
authors.forename: Irma
authors.initials: I
authors.lastname: Alamilla-Beltrán
authors.forename: Rosario
authors.initials: R
authors.lastname: Han-Alonso
authors.forename: Héctor
authors.initials: H
authors.lastname: Solano-Moreno
authors.forename: Andrea Socorro
authors.initials: AS
authors.lastname: Alvarez-Villaseñor
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Ramírez-Contreras
authors.forename: Clotilde
authors.initials: C
authors.lastname: Fuentes-Orozco
authors.forename: Alejandro
authors.initials: A
authors.lastname: González-Ojeda
mesh_terms: D000577:Amides / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D010149:Postoperative Pain / Q000517:prevention & control*; D000077212:Ropivacaine; D013520:Urologic Surgical Procedures
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D002045:Bupivacaine