title: n-Hydroxyapatite/PCL-Pluronic-PCL Nanocomposites for Tissue Engineering. Part 2: Thermal and Tensile Study.
abstract: In this work a series of nano-hydroxyapatite/poly(ε-caprolactone)-Pluronic-poly(ε-caprolactone) (n-HA/PCFC) nanocomposites has been prepared. Thermal properties of the nanocomposites are studied by thermogravimetry analysis (TGA) and differential scanning calorimetry (DSC). The TGA/DTG results reveal that thermal stability of n-HA/PCFC nanocomposites is improved by incorporation of n-HA into polymer matrix, and the thermo-degradation temperature increased slightly with increasing HA loading. DSC results show that the glass transition temperature (T g) changed by the addition of n-HA. The mechanical properties of the nanocomposites are investigated by tensile testing. The morphology for tensile-fractured surfaces of nanocomposites is observed by scanning electron microscopy. The effect of n-HA contents of nanocomposites on tensile strength and morphology is also discussed.
authors.affiliation: a State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, P. R. China.
authors.forename: Shaozhi
authors.initials: S
authors.lastname: Fu
authors.forename: Gang
authors.initials: G
authors.lastname: Guo
authors.forename: Xinlong
authors.initials: X
authors.lastname: Wang
authors.forename: Liangxue
authors.initials: L
authors.lastname: Zhou
authors.forename: Changyang
authors.initials: C
authors.lastname: Gong
authors.forename: Feng
authors.initials: F
authors.lastname: Luo
authors.forename: Xia
authors.initials: X
authors.lastname: Zhao
authors.forename: Yuquan
authors.initials: Y
authors.lastname: Wei
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qian
mesh_terms: D002152:Calorimetry, Differential Scanning; D017886:Durapatite / Q000737:chemistry*; D055119:Elastic Modulus; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D020442:Poloxamer / Q000737:chemistry*; D011091:Polyesters / Q000737:chemistry*; D013696:Temperature; D013718:Tensile Strength; D013818:Thermogravimetry; D023822:Tissue Engineering
chemical_list: D011091:Polyesters; D020442:Poloxamer; C016240:polycaprolactone; D017886:Durapatite