title: Steroidal glycosides with anti-tumor activity from the roots of Cynanchum wallichii Wight.
abstract: Two new steroidal glycosides characterized with 2,6-dideoxypyranoses as component sugars have been isolated from roots of Cynanchum wallichii Wight. Their structure elucidation and cytotoxic activities against HL-60 and PC-3 cells are reported.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Nan
authors.initials: N
authors.lastname: Xu
authors.forename: Zhi-Feng
authors.initials: ZF
authors.lastname: Li
authors.forename: Qi-Hui
authors.initials: QH
authors.lastname: Zhang
authors.forename: Hong-Hua
authors.initials: HH
authors.lastname: Wu
authors.forename: Yue-Hu
authors.initials: YH
authors.lastname: Pei
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D031105:Cynanchum / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010840:Phytosterols; C550643:qinyangshengenin-3-O-beta-D-oleandropyranosyl-(1-4)-beta-D-cymaropyranoside; C550642:qinyangshengenin-3-O-beta-D-oleandropyranosyl-(1-4)-beta-D-oleandropyranosyl-(1-4)-beta-D-cymaropyranoside