title: [Comparative characteristics of hydroxyzine (atarax) and diazepam in the premedication regimen in children in dental practice].
abstract: The effects of hydroxyzine, 2 mg/kg, versus diazepam, 0.5 mg/kg, given orally, on hemodynamics, respiration, and sedative background were studied. The anxiolytic effect of hydroxyzine was higher than that of diazepam. Hydroxyzine showed a minimum effect on hemodynamic and respiratory parameters in children in dental practice before oral sanitation using general anesthesia.
authors.forename: V V
authors.initials: VV
authors.lastname: Milenin
mesh_terms: D000284:Administration, Oral; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods / Q000523:psychology; D054810:Deep Sedation / Q000379:methods / Q000523:psychology; D016854:Dental Anxiety / Q000517:prevention & control* / Q000523:psychology; D003975:Diazepam / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006919:Hydroxyzine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D019647:Oral Surgical Procedures; D011292:Premedication / Q000379:methods*; D012119:Respiration / Q000187:drug effects
chemical_list: D006993:Hypnotics and Sedatives; D006919:Hydroxyzine; D003975:Diazepam