title: Vascular patterns in basal cell carcinoma.
abstract: BACKGROUND
  Dermoscopy has been proved to increase the diagnostic accuracy of basal cell carcinoma (BCC).
  
  
  OBJECTIVE
  To characterize the type and frequency of vascular patterns in superficial and nodular BCCs.
  
  
  METHODS
  We retrospectively analysed the dermoscopic images of 504 histopathologically proven BCCs.
  
  
  RESULTS
  The most common vascular pattern was represented by arborizing vessels (306/504; 60.7%), which were significantly more frequent in nodular BCCs (nBCCs) compared with superficial BCCs (sBCCs), and in pigmented sBCCs vs. non-pigmented sBCCs (P<0.0001). Short fine telangectasias (SFTs) were found in 33.1% (167/504) of cases and were significantly more frequent in sBCCs compared with nBCCs (P<0.0001). Hairpin vessels were detected in 52/504 (10.3%) BCCs. Minor vascular patterns included glomerular vessels (41/504; 8.1%), dotted (21/504; 4.2%), comma vessels (5/504; 1.0%) and polymorphous pattern (9/504; 1.8%).
  
  
  CONCLUSIONS
  Arborizing vessels are prototypic of nBCCs, whereas SFTs are characteristics of sBCCs. Differential diagnosis with squamous cell carcinoma or melanoma is mandatory when a polymorphous pattern is detected.
authors.affiliation: Department of Dermatology, University of L'Aquila, L'Aquila, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Micantonio
authors.forename: A
authors.initials: A
authors.lastname: Gulia
authors.forename: E
authors.initials: E
authors.lastname: Altobelli
authors.forename: A
authors.initials: A
authors.lastname: Di Cesare
authors.forename: R
authors.initials: R
authors.lastname: Fidanza
authors.forename: A
authors.initials: A
authors.lastname: Riitano
authors.forename: M C
authors.initials: MC
authors.lastname: Fargnoli
authors.forename: K
authors.initials: K
authors.lastname: Peris
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000098:blood supply* / Q000175:diagnosis / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D046169:Dermoscopy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000098:blood supply* / Q000175:diagnosis / Q000473:pathology*; D055815:Young Adult