title: Initial evaluation of Permacol bioprosthesis for the repair of complex incisional and parastomal hernias.
abstract: OBJECTIVE
  Repair of complex hernias with synthetic mesh is associated with a significant complication rate, which may necessitate mesh removal. Recent studies have reported good results with the use of collagen-based prosthesis for complicated or infected abdominal hernias. The aim of our study was to evaluate an initial experience using Permacol for the repair of complex incisional and parastomal hernias.
  
  
  METHODS
  A retrospective study of patients with massive, recurrent, complex, or infected incisional and hernias who underwent repair with Permacol at a tertiary referral centre was performed.
  
  
  RESULTS
  Between 2003 and 2007, 15 patients underwent repair of complex massive or recurrent hernias with Permacol. Patients were followed up for a median of 377 days (range 85-1905). 16 postoperative complications developed in 11 patients. Two patients developed a recurrence and two patients developed fistulae. No patient has an active infection or required removal of the Permacol. There have been no deaths.
  
  
  CONCLUSIONS
  There is increasing evidence that Permacol mesh can be safely used for complex and contaminated hernia repairs with acceptable overall results.
authors.affiliation: Department of Upper Gastrointestinal Surgery, Castle Hill Hospital, Cottingham, East Yorkshire, UK. a.loganathan@yahoo.co.uk
authors.forename: A
authors.initials: A
authors.lastname: Loganathan
authors.forename: W G
authors.initials: WG
authors.lastname: Ainslie
authors.forename: K R
authors.initials: KR
authors.lastname: Wedgwood
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D046449:Hernia, Abdominal / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012008:Recurrence; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; C422414:Permacol; D003094:Collagen