title: In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria.
abstract: OBJECTIVE
  The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms.
  
  
  METHODS
  The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus planktonic cells and biofilms in vitro.
  
  
  RESULTS
  P aeruginosa, S epidermidis, and S aureus planktonic cells decreased by a mean of 5.10, 4.99, and 5.22 log10 colony-forming units/mL, respectively, with 4 Qoustic Wound Therapy System treatment minutes. After 10 minutes of treatment, P aeruginosa, S epidermidis, and S aureus biofilms decreased by a mean of 1.34, 1.46, and 1.02 log10 colony-forming units/cm, respectively.
  
  
  CONCLUSIONS
  The Qoustic Wound Therapy System, using the Qoustic Qurette, kills planktonic bacteria and reduces bacterial biofilms in vitro.
authors.affiliation: Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
authors.forename: Melissa J
authors.initials: MJ
authors.lastname: Karau
authors.forename: Kerryl E
authors.initials: KE
authors.lastname: Piper
authors.forename: James M
authors.initials: JM
authors.lastname: Steckelberg
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Kavros
authors.forename: Robin
authors.initials: R
authors.lastname: Patel
mesh_terms: D001424:Bacterial Infections / Q000382:microbiology* / Q000628:therapy*; D018441:Biofilms; D015169:Colony Count, Microbial; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000254:growth & development; D013211:Staphylococcus aureus / Q000254:growth & development; D013212:Staphylococcus epidermidis / Q000254:growth & development; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods*; D014945:Wound Healing; D014946:Wound Infection / Q000382:microbiology* / Q000628:therapy*