title: Left ventricular endocardial definition enhancement using perflutren microsphere contrast echocardiography during peripheral venoarterial extracorporeal membranous oxygenation.
abstract: Contrast echocardiography provides incremental benefit in patients with nondiagnostic imaging, particularly in the intensive care setting. There are minimal data regarding its use in patients on mechanical cardiac support devices. This case highlights the additional diagnostic information provided with contrast-enhanced imaging in a patient with shock, supported by a peripherally cannulated extra-corporeal membranous oxygenation (ECMO) device. The signal persistence was reduced compared to the conventional setting, as anticipated but the concentration of perflutren microspheres remained sufficient to provide satisfactory endocardial definition, despite passage through a centrifugal pump. There was no adverse affect on the patient's cardiorespiratory status or ECMO function.
authors.affiliation: Department of Echocardiography, The Prince Charles Hospital, Brisbane, Queensland, Australia. david_platts@health.qld.gov.au
authors.forename: David
authors.initials: D
authors.lastname: Platts
authors.forename: John F
authors.initials: JF
authors.lastname: Fraser
authors.forename: Daniel
authors.initials: D
authors.lastname: Mullany
authors.forename: Darryl
authors.initials: D
authors.lastname: Burstow
mesh_terms: D000293:Adolescent; D003287:Contrast Media; D004452:Echocardiography / Q000379:methods*; D004699:Endocardium / Q000000981:diagnostic imaging; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D005260:Female; D005466:Fluorocarbons; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008863:Microspheres; D018084:Ultrasonography, Interventional / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000628:therapy*
chemical_list: D003287:Contrast Media; D005466:Fluorocarbons; C042852:perflutren