Probiotic therapy for irritable bowel syndrome.
The etiology of irritable bowel syndrome (IBS) is thought to be multifactorial, with several factors (including alterations in gut motility, small-bowel bacterial overgrowth, microscopic inflammation, and visceral hypersensitivity) potentially playing a role. Recent studies have suggested that probiotics may be useful in the treatment of IBS. Although the exact mechanism for how probiotics may aid in the reduction of symptoms commonly found in IBS is unknown, the effects of probiotics on alterations in gut bacteria appear to play a part. This review focuses on recent studies examining the role of probiotics in the treatment of IBS.
Aragon
George
G
Drs. Aragon and Graham are Gastroenterology Fellows at the George Washington University School of Medicine in Washington, DC.
Graham
Deborah B
DB
Borum
Marie
M
Doman
David B
DB