title: Current waveforms for neural stimulation-charge delivery with reduced maximum electrode voltage.
abstract: This paper contains results on the design of electrical signals for delivering charge through electrodes to achieve neural stimulation while reducing the peak electrode voltage. A generalization of the usual constant current stimulation phase to a stepped current waveform is presented. Techniques based on optimization and linear dynamic system theory are then applied to design the magnitude of each current segment in such a way as to minimize the maximum electrode voltage, while transferring a designated quantity of charge in a specified time. Experimental results are provided which validate the approach in saline and in neural tissue.
authors.affiliation: National Information and Communications Technologies Australia (NICTA) Victoria Research Laboratory (VRL), Department of Electrical and Electronic Engineering, University of Melbourne, Parkville,Vic. 3010, Australia. mark.halpern@nicta.com.au
authors.forename: Mark Edward
authors.initials: ME
authors.lastname: Halpern
authors.forename: James
authors.initials: J
authors.lastname: Fallon
mesh_terms: D000465:Algorithms; D000818:Animals; D001921:Brain / Q000502:physiology*; D002415:Cats; D003198:Computer Simulation; D046690:Deep Brain Stimulation / Q000379:methods*; D004567:Electrodes, Implanted; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D016014:Linear Models; D012815:Signal Processing, Computer-Assisted