title: Campylobacter jejuni and Campylobacter coli in children from communities in Northeastern Brazil: molecular detection and relation to nutritional status.
abstract: This study determined the prevalence of Campylobacter jejuni/coli and its relation with nutritional status in children from Northeastern Brazil. This was a case-control study design. Stool samples were evaluated for hipO (C. jejuni), ask (C. coli), and cdtABC (C. jejuni's cytolethal distending toxin) genes. The nutritional status from these children was assessed by anthropometric measures and z-scores. C. jejuni and C. coli were detected in 9.6% (8/83) and 6.0% (5/83) in the diarrhea group and in 7.2% (6/83) and 1.2% (1/83) of the nondiarrhea group, respectively. Children with positive molecular detection of C. jejuni showed significantly lower z-scores than children without C. jejuni. The cdtABC operon was found in 57% of hipO(+) samples. C. jejuni/coli prevalence was similar in diarrhea and nondiarrhea groups. There was a significant association of C. jejuni infection with lower nutritional status.
authors.affiliation: Institute of Biomedicine for Brazilian Semi-Arid and Clinical Research Unit/Center for Global Health, Federal University of Ceara, Fortaleza, Brazil. jquetz@gmail.com
authors.forename: Josiane
authors.initials: J
authors.lastname: da Silva Quetz
authors.forename: Ila Fernanda Nunes
authors.initials: IF
authors.lastname: Lima
authors.forename: Alexandre
authors.initials: A
authors.lastname: Havt
authors.forename: Eunice Bobo
authors.initials: EB
authors.lastname: de Carvalho
authors.forename: Noélia Leal
authors.initials: NL
authors.lastname: Lima
authors.forename: Alberto Melo
authors.initials: AM
authors.lastname: Soares
authors.forename: Rosa Maria Salani
authors.initials: RM
authors.lastname: Mota
authors.forename: Richard Littleton
authors.initials: RL
authors.lastname: Guerrant
authors.forename: Aldo Angelo Moreira
authors.initials: AA
authors.lastname: Lima
mesh_terms: D000886:Anthropometry / Q000379:methods; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics; D001938:Brazil; D002169:Campylobacter Infections / Q000453:epidemiology* / Q000382:microbiology; D017000:Campylobacter coli / Q000302:isolation & purification*; D016123:Campylobacter jejuni / Q000302:isolation & purification*; D016022:Case-Control Studies; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009752:Nutritional Status; D015995:Prevalence
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins