title: Enhancement of C2C12 differentiation by perfluorocarbon-mediated oxygen delivery.
abstract: We have studied the effect of enhanced oxygen delivery by perfluorocarbons on the differentiation of C2C12 cells. The extent of differentiation was assessed by means of phase contrast/fluorescence microscopy, active tension measurement and the glucose consumption/lactate production rates. We found that enhanced oxygen delivery is suitable for full differentiation of C2C12 cells.
authors.affiliation: Toyota Central Research and Development Labs., Inc., 41-1 Yokomichi, Nagakute, Aichi 480-1192, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Fujita
authors.forename: Kazunori
authors.initials: K
authors.lastname: Shimizu
authors.forename: Yuki
authors.initials: Y
authors.lastname: Morioka
authors.forename: Eiji
authors.initials: E
authors.lastname: Nagamori
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002460:Cell Line; D005466:Fluorocarbons / Q000493:pharmacokinetics*; D051379:Mice; D018485:Muscle Fibers, Skeletal / Q000166:cytology* / Q000378:metabolism*; D032446:Myoblasts / Q000166:cytology* / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*
chemical_list: D005466:Fluorocarbons; D010100:Oxygen