title: [Significance of MR angiography for imaging diagnostics of carotid artery diseases].
abstract: During the last decade, magnetic resonance angiography (MRA) evolved to an essential method for radiological diagnostics of extracranial arteries' diseases. Contrast enhanced MRA enables meanwhile the acquisition of angiographic series in high diagnostic quality comparable to that originating from conventional DSA. Due to MRA, conventional DSA anymore plays a crucial role in the diagnostic assessment of carotid artery disease or highly vascularised tumors of the head and neck region. Besides reliable quantification of carotid stenoses, highly resolved MRI sequences provide a promising approach for characterization of plaque morphologies and thereby contribute to turn the risk for a stroke calculable. Furthermore, MRA has nearly replaced DSA in radiographics of carotid artery dissections whereas MRA has especially emerged as an appropriate method to visualize the intramural hematoma which is evidentiary for the diagnosis. However, not all methods of MRA are equivalent in respect to their diagnostic value. While CE MRA is able to completely substitute DSA in many clinical questions, applicability of flow-dependent Time-of-flight (TOF) or phase-contrast (PC) MRA is limited due to their distinct susceptibility to motion or flow-related artefacts.
authors.affiliation: Abteilung Radiologie, Deutsches Krebsforschungszentrum Heidelberg, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland. l.schuster@dkfz.de
authors.forename: L
authors.initials: L
authors.lastname: Schuster
authors.forename: T
authors.initials: T
authors.lastname: Hauser
authors.forename: M
authors.initials: M
authors.lastname: Essig
mesh_terms: D015901:Angiography, Digital Subtraction; D002340:Carotid Artery Diseases / Q000175:diagnosis*; D020215:Carotid Artery, Internal, Dissection; D016893:Carotid Stenosis / Q000175:diagnosis; D002544:Cerebral Infarction / Q000175:diagnosis / Q000517:prevention & control; D003287:Contrast Media / Q000008:administration & dosage; D006406:Hematoma / Q000175:diagnosis; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D012307:Risk Factors; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media