A seven-year experience with patients with juvenile nasopharyngeal angiofibroma.
Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in adolescent males. It originates in the nasopharynx.


OBJECTIVE
To present the experience of JNA management at an Otorhinolaryngology Service between 2001 and 2008.


METHODS
Demographical data, clinical presentation, investigations as well as the treatment of sixteen JNA patients were reviewed and collected from medical records from the ORL Service.


METHODS
Cross-sectional, retrospective and descriptive study.


RESULTS
All JNA patients were male. The average age at diagnosis was 16.8 years (range 9-23 years). More than 56% of the patients were classified as Fisch II. Preoperative embolization was carried out in ten (62.5%) patients. All 16 patients were submitted to primary surgical resection. Two patients (66.7%) who didn't receive preoperative embolization required intraoperative blood transfusion. The overall recurrence rate was 43.75% and the cure rate was 93.75%.


CONCLUSIONS
Preoperative embolization minimizes intraoperative blood loss. The recurrence rate was related to advanced tumoral stage at diagnostic and the lack of preoperative embolization. Surgery combined with preoperative embolization is the major treatment for JNA. All the patients should undergo preoperative imaging studies, especially CT, to assist in surgical planning and follow-up.
Gaillard
Alfredo Lara
AL
Anastácio
Vanessa Menegatti
VM
Piatto
Vânia Belintani
VB
Maniglia
José Victor
JV
Molina
Fernando Drimel
FD
D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D002648:Child; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000379:methods; D003430:Cross-Sectional Studies; D004621:Embolization, Therapeutic; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D055815:Young Adult