title: [CT-guided radiofrequency ablation of non-small cell lung cancer].
abstract: FUNDAMENTAL AND OBJECTIVE: To present the first experiences with a series of consecutive cases of patients with non-small cell lung cancer (NSCLC) treated with radiofrequency ablation (RFA), considering its clinical applicability, effectiveness and safety.
  
  
  METHODS
  Descriptive study performed from June 2003 to March 2009, with a series of consecutive cases of patients with NSCLC treated with RFA, selected according to well-defined inclusion criteria, in different stages of the disease. The variables studied were local recurrence, complications, staging, demographic and procedure-related variables. Local control was assessed in posterior controls according to CT morphology criteria and/or lesion enhancement after intravenous contrast. Survival curves were estimated. Statistical analysis was performed with SPSS version 15.0 application.
  
  
  RESULTS
  We studied 15 patients (46-88 years), diagnosed with NSCLC in different stages, in a total of 22 sessions. After 1 year of follow up, 75% of lesions showed no local recurrence (15). The progression-free survival and disease-free survival in localized stage at one year were 81,3% and 75% respectively. In 8 of 22 sessions there were post-procedure complications (36.36%). Of all complications (14), 28.5% were pneumothorax, 21.4% alveolar hemorrhage and 7.1% pulmonary infarction.
  
  
  CONCLUSIONS
  ARF is clinically useful in the treatment of patients with inoperable NSCLC, considering the high percentage of local control and few major complications, being thus a plausible, effective and safe therapeutic alternative.
authors.affiliation: Departamento de Diagnóstico por Imagen, Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España. jcamacho@fhalcorcon.es
authors.forename: Jonathan
authors.initials: J
authors.lastname: Camacho Romero
authors.forename: José María
authors.initials: JM
authors.lastname: Oliver Goldaracena
authors.forename: Gil
authors.initials: G
authors.lastname: Rodríguez Caravaca
authors.forename: Susana
authors.initials: S
authors.lastname: Hernando Polo
authors.forename: José
authors.initials: J
authors.lastname: Martel Villagrán
authors.forename: Miguel
authors.initials: M
authors.lastname: Trapero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000601:surgery*; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D015641:Radiography, Interventional; D012189:Retrospective Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome