The relationship between glucose tolerance and severity of coronary artery disease using the Gensini score.
Consecutive patients (n = 235) with coronary ischemia were studied; 69 patients (29%) had diabetes. An oral glucose tolerance test (OGTT) was administered to the 166 patients without diabetes; 76 (46%) had normal glucose tolerance (group I = NGT), 68 (41%) had impaired glucose tolerance ([IGT] group II = IGT), and 22 (13%) had diabetic glucose tolerance (DGT). The DGT patients were added to the known diabetics forming (Group III; n = 91). Multivessel disease was significantly more prevalent in group III; 30 patients (43%) in group I, 32 patients (51%) in group II, and 57 patients (69%) in group III (P = .002). Gensini scores were 43.20 ± 24.92 in group I, 54.22 ± 42.61 in group II, and 60.59 ± 38.21 in group III. (P = .037) The severity of coronary artery disease is related to abnormal glucose tolerance. Patients with IGT could be neglected in terms of interventions focused to improve risk factors.
Nurkalem
Zekeriya
Z
Siyami Ersek Cardiovascular and Thoracic Surgery Center, Training and Research Hospital, Cardiology Department, Istanbul, Turkey. zeknurkalem@yahoo.com
Hasdemir
Hakan
H
Ergelen
Mehmet
M
Aksu
Huseyin
H
Sahin
Irfan
I
Erer
Betul
B
Yilmaz
Hale Y
HY
Comert
Nuri
N
Sargin
Mehmet
M
Eren
Mehmet
M
D001786:Blood Glucose / Q000032:analysis; D003324:Coronary Artery Disease / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D048909:Diabetes Complications / Q000097:blood; D005260:Female; D018149:Glucose Intolerance / Q000150:complications*; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012720:Severity of Illness Index
D001786:Blood Glucose