title: Phyllodes tumor of the breast; a case series.
abstract: BACKGROUND
  Phyllodes tumor (PT) is a rare neoplasm comprising less than 1% of all breast tumors. Its clinical spectrum ranges from a benign and locally recurrent form of behavior to malignant and metastatic forms. The aim of the study was to evaluate the clinical characteristics, treatment regimens, survival and late complications in patients with PT.
  
  
  METHODS
  We retrospectively reviewed the medical records of 10 women who were treated for PT in our center between 1998 and 2002. All cases were histologically examined by an experienced breast pathologist, and tumors were classified as benign, borderline malignant or malignant according to standard histological criteria.
  
  
  RESULTS
  The median age at diagnosis was 45.5 years (range: 21-69 years). Seven (70%) of 10 tumors were benign and 3 (30%) were malignant. The median tumor size was 29 mm (range: 12-80 mm). The least safe margin was 1 cm. Three of 10 patients had malignant PT and underwent simple mastectomy. Local recurrence was determined in no patients. Only one patient had lung metastasis. Median follow-up period was 62 months (range, 12-96 months). The patient with lung metastasis was treated with doxorubicine but died one year after the operation.
  
  
  CONCLUSIONS
  PT is a rare neoplasm of the breast. It resembles fibroadenoma. Local excision with appropriate surgical margins seems adequate in all patients (Tab. 1, Fig. 3, Ref. 15). Full Text (Free, PDF) www.bmj.sk.
authors.affiliation: Gazi University Medical School, Department of General Surgery, Ankara, Turkey. makin@gazi.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Akin
authors.forename: Oktay
authors.initials: O
authors.lastname: Irkorucu
authors.forename: Hande
authors.initials: H
authors.lastname: Koksal
authors.forename: Ipek Isik
authors.initials: II
authors.lastname: Gonul
authors.forename: Serap
authors.initials: S
authors.lastname: Gultekin
authors.forename: Osman
authors.initials: O
authors.lastname: Kurukahvecioglu
authors.forename: Ahmet Ziya
authors.initials: AZ
authors.lastname: Anadol
authors.forename: Ercument
authors.initials: E
authors.lastname: Tekin
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000473:pathology / Q000601:surgery; D055815:Young Adult