Immune disease expressed in liver and platelets in an adolescent: a case report.
We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy.The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.
Antunes
Henedina
H
Adolescents Unit and Gastrenterology, Hepatology and Nutrition Unit, Pediatrics Department, Braga Hospital, and Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal.
Rocha
Ruben
R
Silva
Nicole
N
Pontes
Teresa
T
Antunes
Ana
A
Martins
Sofia
S
D000293:Adolescent; D015551:Autoimmunity; D001706:Biopsy; D003937:Diagnosis, Differential; D019693:Hepatitis, Autoimmune / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology