Novel coumarin derivatives as potential antidyslipidemic agents.
A series of novel benzocoumarin derivatives were synthesized and evaluated for their in vivo antidyslipidemic and in vitro antioxidant activities. Among 11 compounds tested, 2 compounds showed potent antidyslipidemic activity and 3 compounds showed potent antioxidant activity.
Sashidhara
Koneni V
KV
Medicinal and Process Chemistry Division, Central Drug Research Institute, CSIR, Lucknow 226 001, India. sashidhar123@gmail.com
Kumar
Abdhesh
A
Kumar
Manoj
M
Sonkar
Ravi
R
Bhatia
Gitika
G
Khanna
A K
AK
D003374:Coumarins / Q000737:chemistry / Q000627:therapeutic use*; D050171:Dyslipidemias / Q000188:drug therapy*; D006801:Humans
D003374:Coumarins; C030123:coumarin