Malabsorption syndrome and leukotriene inhibitor.
Previously described treatments used for eosinophilic diseases of the gastrointestinal tract have included dietary restrictions primarily of cow milk protein, anti-inflammatory therapy utilizing suplatast, budesonide and corticosteroids, cromolyn sodium, anti-histamines and oral inhalable steroids. We describe a 12-year-old girl with diarrhea and malabsorption, who was later diagnosed to have eosinophilic gastroenteritis, was unresponsive to standard therapies, but exhibited marked improvement with use of montelukast.
Selva Kumar
Chinnakkannan
C
Department of Pediatrics, Sri Venkateswara Medical College and Research Institute, Arriyur, Puduchery, India.
Das
Rashmi Ranjan
RR
Balakrishnan
C D
CD
Balagurunathan
K
K
Chaudhuri
Kaustabh
K
D000085:Acetates / Q000627:therapeutic use*; D002648:Child; D003521:Cyclopropanes; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis; D016099:Endoscopy, Gastrointestinal; D004751:Enteritis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005756:Gastritis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use*; D008286:Malabsorption Syndromes / Q000175:diagnosis / Q000209:etiology; D011804:Quinolines / Q000627:therapeutic use*; D013440:Sulfides; D016896:Treatment Outcome
D000085:Acetates; D003521:Cyclopropanes; D020024:Leukotriene Antagonists; D011804:Quinolines; D013440:Sulfides; C093875:montelukast