Septic shock caused by Plesiomonas shigelloides in a patient with sickle beta-zero thalassemia.
Invasive infection and extraintestinal complications are rarely caused by Plesiomonas shigelloides, a waterborne bacterium belonging to the Vibrionaceae family. We report a case of a 16-year-old female patient with sickle beta-zero thalassemia who survived septic shock caused by P. shigelloides associated with secondary acute respiratory distress syndrome and disseminated intravascular coagulation. Treatment with a carbapenem was successful, and the patient recovered without any sequelae. The previous reports of P. shigelloides sepsis are cited, and possible pathogenic mechanisms are discussed.
Auxiliadora-Martins
Maria
M
Centro de Terapia Intensiva (Campus), Departamento de Cirurgia e Anatomia, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, HCFMRP-USP, Ribeirão Preto, SP, Brasil. mamartins@hcrp.usp.br <mamartins@hcrp.usp.br>
Bellissimo-Rodrigues
Fernando
F
Viana
Jaciara Machado
JM
Teixeira
Gil Cezar Alkmin
GC
Nicolini
Edson Antônio
EA
Cordeiro
Kátia Simone Muniz
KS
Colozza
Giovana
G
Martinez
Roberto
R
Martins-Filho
Olindo Assis
OA
Basile-Filho
Anibal
A
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D015780:Carbapenems / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D016638:Critical Illness; D004211:Disseminated Intravascular Coagulation; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D006451:Hemoglobin, Sickle / Q000032:analysis*; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D007362:Intensive Care Units; D008795:Metronidazole / Q000627:therapeutic use; D016981:Plesiomonas / Q000302:isolation & purification*; D012128:Respiratory Distress Syndrome; D012772:Shock, Septic / Q000188:drug therapy* / Q000382:microbiology; D013789:Thalassemia / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D015780:Carbapenems; D006451:Hemoglobin, Sickle; D008795:Metronidazole; D015378:Imipenem; D002443:Ceftriaxone; D017291:Clarithromycin