Salmonella taking charge.
Pathogens develop creative ways to undermine host defenses. In this issue of Cell Host & Microbe, Bakowski et al. (2010) have unveiled a mechanism by which Salmonella evades lysosomal fusion by using a bacterial protein, SopB, that depletes the phagosomal membrane of negative charge.
Weigele
Bethany A
BA
Department of Microbiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8816, USA.
Alto
Neal M
NM