title: A seven-year experience with patients with juvenile nasopharyngeal angiofibroma.
abstract: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumor in adolescent males. It originates in the nasopharynx.
  
  
  OBJECTIVE
  To present the experience of JNA management at an Otorhinolaryngology Service between 2001 and 2008.
  
  
  METHODS
  Demographical data, clinical presentation, investigations as well as the treatment of sixteen JNA patients were reviewed and collected from medical records from the ORL Service.
  
  
  METHODS
  Cross-sectional, retrospective and descriptive study.
  
  
  RESULTS
  All JNA patients were male. The average age at diagnosis was 16.8 years (range 9-23 years). More than 56% of the patients were classified as Fisch II. Preoperative embolization was carried out in ten (62.5%) patients. All 16 patients were submitted to primary surgical resection. Two patients (66.7%) who didn't receive preoperative embolization required intraoperative blood transfusion. The overall recurrence rate was 43.75% and the cure rate was 93.75%.
  
  
  CONCLUSIONS
  Preoperative embolization minimizes intraoperative blood loss. The recurrence rate was related to advanced tumoral stage at diagnostic and the lack of preoperative embolization. Surgery combined with preoperative embolization is the major treatment for JNA. All the patients should undergo preoperative imaging studies, especially CT, to assist in surgical planning and follow-up.
authors.forename: Alfredo Lara
authors.initials: AL
authors.lastname: Gaillard
authors.forename: Vanessa Menegatti
authors.initials: VM
authors.lastname: Anastácio
authors.forename: Vânia Belintani
authors.initials: VB
authors.lastname: Piatto
authors.forename: José Victor
authors.initials: JV
authors.lastname: Maniglia
authors.forename: Fernando Drimel
authors.initials: FD
authors.lastname: Molina
mesh_terms: D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D002648:Child; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000379:methods; D003430:Cross-Sectional Studies; D004621:Embolization, Therapeutic; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D055815:Young Adult