Fresh-frozen bone allografts in maxillary ridge augmentation: histologic analysis.
Bone allograft has become an alternative to autogenous bone due to its decreased operative trauma and the almost unlimited supply of reconstructive material. The aim of the present study was to histologically evaluate the suitability of fresh-frozen bone graft (test group) used in maxillary ridge augmentation, comparing it to autogenous bone (native maxilla: control group). During the re-entry procedures, 9 months after the fresh-frozen allogeneic bone blocks were placed in the atrophic maxillary ridges, bone cores were removed with a trephine bur from test and control treatments in the same patient. Routine histologic processing using hematoxylin and eosin and Picrosirius staining was performed. Mature and immature collagen area and density analysis were carried out for both groups under polarization. The results of Student's t test for paired samples (P > .05) showed no statistically significant difference in mature and immature collagen area or density percentage between test and control groups. Histologically similar bone formation patterns were observed in both groups. We concluded that fresh-frozen bone allograft is a biologically acceptable alternative for augmentation of the deficient alveolar ridge, showing a similar collagen pattern to that of autogenous bone.
Contar
Cintia Mussi Milani
CM
School of Dentistry, Universidade Tuiuti do Paraná, Brazil. cintiacontar@hotmail.com
Sarot
João Rodrigo
JR
da Costa
Maite Barroso
MB
Bordini
Jayme
J
de Lima
Antonio Adilson Soares
AA
Alanis
Luciana Reis Azevedo
LR
Trevilatto
Paula Cristina
PC
Machado
Maria Ângela Naval
MÂ
D000328:Adult; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D015519:Bone Density; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods*; D003094:Collagen / Q000737:chemistry; D005260:Female; D005615:Freezing; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008875:Middle Aged; D014183:Transplantation, Heterologous
D003094:Collagen