Beneficial effect of epilepsy surgery in a case of childhood non-paraneoplastic limbic encephalitis.
This 15-year-old girl had subacute onset of secondary generalized seizures, confusion, and subsequent memory decline. MRI showed bilateral hippocampal swelling progressing to unilateral mesial temporal sclerosis (MTS) within 12 months. Epilepsy surgery was performed, and laboratory data were consistent with non-paraneoplastic limbic encephalitis. 18 months after epilepsy surgery, the patient is seizure-free with stable cognitive functions.
Muehlebner
Angelika
A
Department of Pediatrics, Medical University Vienna, Waehringer Guertel 18-20, Vienna, Austria.
Groeppel
Gudrun
G
Pahs
Gerald
G
Hainfellner
Johannes A
JA
Prayer
Daniela
D
Czech
Thomas
T
Feucht
Martha
M
D000293:Adolescent; D005260:Female; D006624:Hippocampus / Q000473:pathology / Q000601:surgery*; D006801:Humans; D020363:Limbic Encephalitis / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D012598:Sclerosis / Q000150:complications / Q000473:pathology / Q000601:surgery; D012640:Seizures / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome