New doxorubicin N-acyl hydrazones with improved efficacy and cell line specificity show modes of action different from the parent drug.
Effenberger
K
K
Organic Chemistry Laboratory, University of Bayreuth, Baryreuth, Germany.
Breyer
S
S
Ocker
M
M
Schobert
R
R
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004317:Doxorubicin / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D006835:Hydrazones / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D006835:Hydrazones; D004317:Doxorubicin