title: Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels.
abstract: CONCLUSIONS
  Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research.
  
  
  METHODS
  Assemble is released under an open-source license (MIT license) and is freely available at http://bioinformatics.org/assemble. It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.
authors.affiliation: Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France. f.jossinet@ibmc-cnrs.unistra.fr
authors.forename: Fabrice
authors.initials: F
authors.lastname: Jossinet
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Ludwig
authors.forename: Eric
authors.initials: E
authors.lastname: Westhof
mesh_terms: D019295:Computational Biology; D003196:Computer Graphics; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D017423:Sequence Analysis, RNA; D012984:Software; D014584:User-Computer Interface
chemical_list: D012313:RNA