title: Activated charcoal: to give or not to give?
abstract: There has been much debate about the use of activated charcoal in patients who have taken overdoses and then present to Emergency Departments. There are clinical trials, research and position statements that have examined the effectiveness of activated charcoal in a number of overdoses of different medications, but there is still a debate surrounding the evidence based practice of administering activated charcoal in patients who have taken a drug overdose due to lack of evidence. This article will examine on the two main guidelines on activated charcoal, one produced by the National Institute for Clinical Excellence and the second produced by American Academy of Clinical Toxicology. It will discuss the methods of administration on activated charcoal, contraindications and the difficulties or challenges in adhering to these guidelines in the clinical setting.
authors.affiliation: Emergency Dept, Bristol Royal Infirmary, Bristol BS2 8HW, UK.
authors.forename: Georgina M
authors.initials: GM
authors.lastname: Elder
mesh_terms: D000931:Antidotes / Q000494:pharmacology / Q000627:therapeutic use*; D002606:Charcoal / Q000494:pharmacology / Q000627:therapeutic use*; D034462:Dissent and Disputes; D004334:Drug Administration Schedule; D062787:Drug Overdose / Q000188:drug therapy*; D004636:Emergency Service, Hospital; D004638:Emergency Treatment / Q000379:methods* / Q000451:nursing / Q000592:standards; D055317:Evidence-Based Practice; D019983:Guideline Adherence; D006801:Humans; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D013406:Suicide, Attempted / Q000706:statistics & numerical data; D013997:Time Factors
chemical_list: D000931:Antidotes; D002606:Charcoal