Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan.
Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at baseline. When participants were divided into tertiles, all-cause mortality increased significantly as baPWV increased (P<0.001). Participants in the highest baPWV tertile showed an increased risk of all-cause mortality evidenced by a multivariable adjusted hazard ratio of 6.8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population.
Turin
Tanvir Chowdhury
TC
Department of Health Science, Shiga University of Medical Science, Shiga, Japan. turin@belle.shiga-med.ac.jp
Kita
Yoshikuni
Y
Rumana
Nahid
N
Takashima
Naoyuki
N
Kadota
Aya
A
Matsui
Kenji
K
Sugihara
Hideki
H
Morita
Yutaka
Y
Nakamura
Yasuyuki
Y
Miura
Katsuyuki
K
Ueshima
Hirotsugu
H
D000328:Adult; D000368:Aged; D055109:Ankle Brachial Index; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009026:Mortality; D011673:Pulsatile Flow / Q000502:physiology*