title: Association of adenoid surface biofilm formation and chronic otitis media with effusion.
abstract: OBJECTIVE
  To investigate bacterial biofilm formation on the adenoid surface of pediatric patients undergoing adenoidectomy and to reveal whether this formation is associated with chronic otitis media with effusion (COME).
  
  
  METHODS
  Prospective, single-blinded study with scanning electron microscopy.
  
  
  METHODS
  Dişkapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey.
  
  
  METHODS
  Thirty-four children between 4 and 15 years of age (mean age, 7.76 years) who had undergone adenoidectomy from June 1 through December 31, 2007, were divided into 2 groups. The first group (17 children) had undergone adenoidectomy alone, whereas the second group (17 children) had undergone adenoidectomy combined with ventilation tube insertion for COME.
  
  
  METHODS
  Scanning electron microscopy was performed to observe biofilm formation on the surface of adenoid tissues. The biofilm formation was graded according to extension. The roles of adenoid size, age, sex, and duration of COME symptoms were evaluated.
  
  
  RESULTS
  Biofilm formation was detected on all samples. Adenoids removed from patients with COME had higher-grade biofilm formation than the other group (P = .001). No correlation was found between adenoid size and biofilm formation.
  
  
  CONCLUSIONS
  In pediatric patients, adenoid surface biofilm formation may be associated with COME etiopathogenesis.
authors.affiliation: Kizilirmak Mah 53.Cad 35/10, 06520-Cukurambar Ankara, Turkey. guleserkilic@yahoo.com
authors.forename: Güleser
authors.initials: G
authors.lastname: Saylam
authors.forename: Emel Cadalli
authors.initials: EC
authors.lastname: Tatar
authors.forename: Ilkan
authors.initials: I
authors.lastname: Tatar
authors.forename: Ali
authors.initials: A
authors.lastname: Ozdek
authors.forename: Hakan
authors.initials: H
authors.lastname: Korkmaz
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000382:microbiology* / Q000473:pathology; D000293:Adolescent; D018441:Biofilms; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D010034:Otitis Media with Effusion / Q000209:etiology*; D011446:Prospective Studies