In vivo estimation of the short-range stiffness of cross-bridges from joint rotation.
Short-range stiffness (SRS) is a mechanical property of muscles that is characterized by a disproportionally high stiffness within a short length range during both lengthening and shortening movements. SRS is attributed to the cross-bridges and is beneficial for stabilizing a joint during, e.g., postural conditions. Thus far, SRS has been estimated mainly on isolated mammalian muscles. In this study we presented a method to estimate SRS in vivo in the human wrist joint. SRS was estimated at joint level in the angular domain (Nm/rad) for both flexion and extension rotations of the human wrist in nine healthy subjects. Wrist rotations of 0.15rad at 3rad/s were imposed at eight levels of voluntary contraction ranging from 0 to 2.1Nm by means of a single axis manipulator. Flexion and extension SRS of the wrist joint was estimated consistently and accurately using a dynamic nonlinear model that was fitted onto the recorded wrist torque. SRS increased monotonically with torque in a way consistent with previous studies on isolated muscles. It is concluded that in vivo measurement of joint SRS represents the population of coupled cross-bridges in wrist flexor and extensor muscles. In its current form, the presented technique can be used for clinical applications in many neurological and muscular diseases where altered joint torque and (dissociated) joint stiffness are important clinical parameters.
van Eesbeek
Stijn
S
Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Laboratory for Neuromuscular Control, Delft University of Technology, Mekelweg 2, Delft, The Netherlands.
de Groot
Jurriaan H
JH
van der Helm
Frans C T
FC
de Vlugt
Erwin
E
D000328:Adult; D001696:Biomechanical Phenomena; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D019370:Observation; D016059:Range of Motion, Articular; D019415:Torque; D014955:Wrist Joint / Q000502:physiology*