title: Cardiac rehabilitation programs improve metabolic parameters in patients with the metabolic syndrome and coronary heart disease.
abstract: This study was performed to determine the effectiveness of a cardiac rehabilitation and exercise training program on metabolic parameters and coronary risk factors in patients with the metabolic syndrome and coronary heart disease. The study involved 642 patients with coronary heart disease. Of them, 171 (26.7%) fulfilled criteria for the metabolic syndrome. Clinical data, laboratory tests, and exercise testing were performed before and after the program, which lasted 2 to 3 months. Except for waist circumference, there were no significant differences between groups; blood pressure, high-density lipoprotein cholesterol, triglycerides, and fasting glucose improvements during the follow-up were higher in patients with the metabolic syndrome (all P<.001). At study end, in patients with the metabolic syndrome, functional capacity increased by 26.45% ( P<.001), as measured by metabolic equivalents, with a slight increase of 1.25% ( P=not significant) in the double product. Patients with the metabolic syndrome who took part in this secondary prevention program reported improvements in cardiovascular risk profile and functional capacity.
authors.affiliation: Department of Cardiology, Infanta Sofia Hospital, San Sebastián de los Reyes, Madrid, Spain. ignacio.plaza@salud.madrid.org
authors.forename: Ignacio P
authors.initials: IP
authors.lastname: Pérez
authors.forename: Maria A
authors.initials: MA
authors.lastname: Zapata
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Cervantes
authors.forename: Rosario M
authors.initials: RM
authors.lastname: Jarabo
authors.forename: Cristina
authors.initials: C
authors.lastname: Grande
authors.forename: Rose
authors.initials: R
authors.lastname: Plaza
authors.forename: Sara
authors.initials: S
authors.lastname: Garcia
authors.forename: Miriam L
authors.initials: ML
authors.lastname: Rodriguez
authors.forename: Silvia
authors.initials: S
authors.lastname: Crespo
authors.forename: Jesús
authors.initials: J
authors.lastname: Perea
mesh_terms: D001786:Blood Glucose; D001794:Blood Pressure; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D005080:Exercise Test; D005081:Exercise Therapy; D017079:Exercise Tolerance; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation*; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome; D055105:Waist Circumference
chemical_list: D001786:Blood Glucose; D008055:Lipids