Diabetes and cancer: a consensus report.
Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning 1) the association between diabetes and cancer incidence or prognosis; 2) risk factors common to both diabetes and cancer; 3) possible biologic links between diabetes and cancer risk; and 4) whether diabetes treatments influence the risk of cancer or cancer prognosis. In addition, key unanswered questions for future research are posed.
Giovannucci
Edward
E
Departments of Nutrition and Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA. egiovann@hsph.harvard.edu
Harlan
David M
DM
Archer
Michael C
MC
Bergenstal
Richard M
RM
Gapstur
Susan M
SM
Habel
Laurel A
LA
Pollak
Michael
M
Regensteiner
Judith G
JG
Yee
Douglas
D
D000367:Age Factors; D000428:Alcohol Drinking; D015992:Body Mass Index; D016207:Cytokines / Q000378:metabolism; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy; D004032:Diet; D004967:Estrogens / Q000097:blood; D006801:Humans; D006943:Hyperglycemia / Q000150:complications; D006946:Hyperinsulinism / Q000150:complications; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000009:adverse effects; D054795:Incretins / Q000008:administration & dosage / Q000009:adverse effects; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D008687:Metformin / Q000008:administration & dosage / Q000009:adverse effects; D009043:Motor Activity; D009369:Neoplasms / Q000150:complications* / Q000209:etiology* / Q000378:metabolism; D050177:Overweight; D044469:Racial Groups; D017526:Receptor, IGF Type 1 / Q000378:metabolism; D011972:Receptor, Insulin / Q000378:metabolism; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013453:Sulfonylurea Compounds / Q000008:administration & dosage / Q000009:adverse effects; D013739:Testosterone / Q000097:blood; D045162:Thiazolidinediones / Q000008:administration & dosage / Q000009:adverse effects
D016207:Cytokines; D004967:Estrogens; D007004:Hypoglycemic Agents; D054795:Incretins; D007328:Insulin; D013453:Sulfonylurea Compounds; D045162:Thiazolidinediones; D013739:Testosterone; D008687:Metformin; D017526:Receptor, IGF Type 1; D011972:Receptor, Insulin