title: Formation of a cyclic tetrapeptide mimic by thermal azide-alkyne 1,3-dipolar cycloaddition.
abstract: Cyclodimerisation of an appropriate alpha,omega-difunctionalised precursor via thermal azide-alkyne 1,3-dipolar cycloaddition affords a cyclic pseudotetrapeptide whose conformation closely resembles that of a previously prepared analogue containing L-proline and 6-aminopicolinic acid subunits.
authors.affiliation: Technische Universität Kaiserslautern, Fachbereich Chemie-Organische Chemie, Erwin-Schrödinger-Strasse, D-67663 Kaiserslautern, Germany.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Krause
authors.forename: Richard
authors.initials: R
authors.lastname: Goddard
authors.forename: Stefan
authors.initials: S
authors.lastname: Kubik
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D040761:Biomimetic Materials / Q000138:chemical synthesis*; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry*; D013696:Temperature
chemical_list: D000480:Alkynes; D001386:Azides; D010456:Peptides, Cyclic