title: Metabolically exaggerated cardiac reactions to acute psychological stress: the effects of resting blood pressure status and possible underlying mechanisms.
abstract: The study aimed to: confirm that acute stress elicits metabolically exaggerated increases in cardiac activity; test whether individuals with elevated resting blood pressure show more exaggerated cardiac reactions to stress than those who are clearly normotensive; and explore the underlying mechanisms. Cardiovascular activity and oxygen consumption were measured pre-, during, and post-mental stress, and during graded sub-maximal cycling exercise in 11 young men with moderately elevated resting blood pressure and 11 normotensives. Stress provoked increases in cardiac output that were much greater than would be expected from contemporary levels of oxygen consumption. Exaggerated cardiac reactions were larger in the relatively elevated blood pressure group. They also had greater reductions in total peripheral resistance, but not heart rate variability, implying that their more exaggerated cardiac reactions reflected greater beta-adrenergic activation.
authors.affiliation: School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, England, United Kingdom.
authors.forename: George M
authors.initials: GM
authors.lastname: Balanos
authors.forename: Anna C
authors.initials: AC
authors.lastname: Phillips
authors.forename: Michael P
authors.initials: MP
authors.lastname: Frenneaux
authors.forename: David
authors.initials: D
authors.lastname: McIntyre
authors.forename: Christos
authors.initials: C
authors.lastname: Lykidis
authors.forename: Harry S
authors.initials: HS
authors.lastname: Griffin
authors.forename: Douglas
authors.initials: D
authors.lastname: Carroll
mesh_terms: D000293:Adolescent; D001794:Blood Pressure / Q000502:physiology*; D001830:Body Surface Area; D002302:Cardiac Output / Q000502:physiology*; D005080:Exercise Test / Q000379:methods; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood; D012146:Rest / Q000502:physiology*; D013223:Statistics as Topic; D013315:Stress, Psychological / Q000378:metabolism* / Q000503:physiopathology* / Q000534:rehabilitation; D013997:Time Factors; D014655:Vascular Resistance / Q000502:physiology; D055815:Young Adult
chemical_list: D010100:Oxygen