title: [Physiological changes in fibromyalgia].
abstract: A number of physiological changes, some measurable as changes in biomarkers, have been described in fibromyalgia (FM). These include changes in cytokine serum levels and elevated levels of some neurotransmitters in the cerebrospinal fluid. None of these measurements have been validated for diagnosis or follow-up in FM. It is suggested that non-invasive methods which hold the potential to evaluate the severity of FM and serve as therapy targets should be developed in the future.
authors.affiliation: Parker Instituttet, Frederiksberg Hospital, 2000 Frederiksberg, Denmark. henning.bliddal@frh.regionh.dk
authors.forename: Henning
authors.initials: H
authors.lastname: Bliddal
authors.forename: Else Marie
authors.initials: EM
authors.lastname: Bartels
authors.forename: Anders
authors.initials: A
authors.lastname: Jespersen
authors.forename: Bente
authors.initials: B
authors.lastname: Danneskiold-Samsøe
mesh_terms: D015415:Biomarkers / Q000097:blood / Q000134:cerebrospinal fluid; D001921:Brain / Q000503:physiopathology; D016207:Cytokines / Q000097:blood; D005356:Fibromyalgia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D018377:Neurotransmitter Agents / Q000097:blood; D018384:Oxidative Stress
chemical_list: D015415:Biomarkers; D016207:Cytokines; D018377:Neurotransmitter Agents