Selective addition of organolithium reagents to BF2-chelates of beta-ketoesters.
A short, mild, and highly chemoselective addition of organolithium reagents to a BF(2) complex of 3-oxopropanoates has been developed. The methodology allows straightforward preparation of various 1,3-dioxa-BF(2) complexes and subsequently leads to the formation of 1,3-diketones starting from the corresponding 3-oxopropanoates.
Stefane
Bogdan
B
Faculty of Chemistry and Chemical Technology, University of Ljubljana, SI-1000 Ljubljana, Slovenia. bogdan.stefane@fkkt.uni-lj.si
D001896:Boron Compounds / Q000737:chemistry*; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*
D001896:Boron Compounds; D004952:Esters; D007659:Ketones; D009942:Organometallic Compounds; D008094:Lithium