[Characteristics and peculiarities of the course of encephalopathy in diabetes mellitus].
A complex neurological and neuropsychological study of clinical signs of encephalopathy in patients with diabetes mellitus type I (DM I) was carried out. One hundred and twelve patients with different severity and compensation state of DM were examined. A comparison group included 40 patients with discirculatory encephalopathy. Clinical symptoms of encephalopathy were significantly more frequent in patients with DM I, with the presence of frequent hypoglycemias (more than once a week during the last year). The higher level of glycolized hemoglobin (by more than 6.9%) and longer duration of the disease (more than 5 years) were found in the group of patients with encephalopathy. Ultrasonic dopplerography of head and neck vessels and transcranial dopplerography support the involvement of complex vascular factors in the development of encephalopathy in DM I. The special attention is drawn to the changes in microcirculation channel that contribute to the development of encephalopathy in DM I and determine the characteristics of its clinical presentations and course compared to discirculatory encephalopathy.
D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D006801:Humans; D007003:Hypoglycemia; D008833:Microcirculation; D013997:Time Factors