Effect of added monovalent electrolytes on the myelin formation from charged lipids.
The effect of added monovalent electrolytes on the myelin formation of cardiolipin is investigated by optical microscopy observations. The results show that the myelin formation strongly depends on the concentration rather than the type of electrolytes. Myelin figures are observed only in a certain concentration range of electrolytes, and the diameter of the myelin figures decreases with increasing of the electrolyte concentration. Furthermore, the theoretical model of myelin formation for the neutral lipids developed by Huang-Zou-Witten [J.R. Huang, L.N. Zou, T.A. Witten, Eur. Phys. J. E. 18 (2005) 279-285] is extended to the charged membrane system by taking into account the electrostatic interaction to understand the mechanism of myelin formation. The theoretical results well produce our experimental results.
Lin
Meiyu
M
The Key Laboratory of Molecular Engineering of Polymers, Ministry of Education, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.
Li
Li
L
Qiu
Feng
F
Yang
Yuliang
Y
D000818:Animals; D002308:Cardiolipins / Q000737:chemistry*; D002417:Cattle; D004573:Electrolytes / Q000494:pharmacology*; D008853:Microscopy; D009186:Myelin Sheath / Q000187:drug effects / Q000378:metabolism*
D002308:Cardiolipins; D004573:Electrolytes