title: Looking for hypertrophic cardiomyopathy in the community: why is it important?
abstract: Hypertrophic cardiomyopathy (HCM) is an epidemiologically relevant, worldwide spread condition which is frequently perceived as a rare disease. This misconception might be supported by some characteristics of HCM such as its incomplete penetrance and variable age at onset and by the fact that many patients remain asymptomatic for a long course of the disease and are thus unlikely to seek for medical evaluation. Multiple evidences suggest that early diagnosis of HCM is important, not only because it allows the patients to be addressed to appropriate diagnostic work-out and to adequate therapeutical options but because it may trigger the screening of family members with the potential of further, new diagnosis of HCM in previously unsuspected individuals. Increased awareness of the disease among physicians working in community-based hospitals and in outpatients facilities, and a facilitated communication and access to tertiary referral centers, will result into a wider knowledge of the spectrum of the disease, a better access to the state-of-the-art management options for patients, and to a more diffuse practice of genetic evaluation of HCM families.
authors.affiliation: CMSR Veneto Medica, Via Vicenza 204, 36077, Altavilla Vicentina (VI), Italy. snistr@tin.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Nistri
authors.forename: Iacopo
authors.initials: I
authors.lastname: Olivotto
authors.forename: Francesca
authors.initials: F
authors.lastname: Girolami
authors.forename: Francesca
authors.initials: F
authors.lastname: Torricelli
authors.forename: Franco
authors.initials: F
authors.lastname: Cecchi
authors.forename: Magdi H
authors.initials: MH
authors.lastname: Yacoub
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001291:Attitude of Health Personnel; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D024741:Cardiomyopathy, Hypertrophic, Familial / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D042241:Early Diagnosis; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D055815:Young Adult