title: Photocatalytic antibacterial capabilities of TiO(2)-biocidal polymer nanocomposites synthesized by a surface-initiated photopolymerization.
abstract: Novel biocidal polymer-functionalized TiO(2) nanoparticles were prepared by surface-initiated photopolymerization using titania as an initiator. Vinyl monomer mixtures of nontoxic secondary amine-containing biocidal 2-(tert-butylamino)ethyl methacrylate and antifouling ethylene glycol dimethacrylate were used for the antimicrobial polymer shell. It was shown that the synthesized TiO(2)/poly[2-(tert-butylamino)ethyl methacrylate-co-ethylene glycol dimethacrylate] core/shell nanoparticles had enhanced photocatalytic antibacterial properties compared to the pristine TiO(2) nanoparticles due to the combined antibacterial activities of light-driven anti-infective TiO(2) core and biocidal polymer shell. In the dark condition, the TiO(2)/biocidal polymer nanoparticles exhibited high antimicrobial efficiency (95.7%) against gram-positive S. aureus. Furthermore, during UV irradiation, the TiO(2)/biocidal polymer showed improved inhibition of bacterial growth against gram-negative E. coli and gram-positive S. aureus in comparison to the pristine TiO(2) nanoparticles.
authors.affiliation: WCU program of Chemical Convergence for Energy and Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University, Gwanak-gu, Seoul, Korea.
authors.forename: Hyeyoung
authors.initials: H
authors.lastname: Kong
authors.forename: Jooyoung
authors.initials: J
authors.lastname: Song
authors.forename: Jyongsik
authors.initials: J
authors.lastname: Jang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D002384:Catalysis; D008027:Light; D049329:Nanostructures / Q000737:chemistry*; D010777:Photochemistry; D011108:Polymers / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D011108:Polymers; C009495:titanium dioxide; D014025:Titanium