title: Scintigraphy for the detection of myocardial damage in the indeterminate form of Chagas disease.
abstract: BACKGROUND
  Non-invasive cardiological methods have been used for the identification of myocardial damage in Chagas disease.
  
  
  OBJECTIVE
  To verify whether the rest/stress myocardial perfusion scintigraphy is able to identify early myocardial damage in the indeterminate form of Chagas disease.
  
  
  METHODS
  Eighteen patients with the indeterminate form of Chagas Disease and the same number of normal controls, paired by sex and age, underwent rest/stress myocardial scintigraphy using sestamibi-99mTc, aiming at detecting early cardiac damage.
  
  
  RESULTS
  The results did not show perfusion or ventricular function defects in patients at the indeterminate phase of Chagas disease and in the normal controls, except for a patient who presented signs of ventricular dysfunction in the myocardial perfusion scintigraphy with electrocardiographic gating.
  
  
  CONCLUSIONS
  The results of this study, considering the small sample size, showed that the rest/stress myocardial scintigraphy using sestamibi-99mTc is not an effective method to detect early myocardial alterations in the indeterminate form of Chagas disease.
authors.affiliation: Instituto de Medicina Nuclear e Diagnóstico Molecular, Belo Horizonte, MG, Brasil.
authors.forename: Ivana Moura
authors.initials: IM
authors.lastname: Abuhid
authors.forename: Enio Roberto Pietra
authors.initials: ER
authors.lastname: Pedroso
authors.forename: Nilton Alves de
authors.initials: NA
authors.lastname: Rezende
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002598:Chagas Cardiomyopathy / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi