[Fetal myocarditis associated with maternal anti-Ro and anti-La antibodies in the absence of atrioventricular block with good outcome].
We report a case of fetal myocarditis without conductive abnormality in a pregnant woman with anti-Ro/La antibodies. Fetal echocardiography showed myocarditis with ventricular and valvular hyperechogenicity, which was confirmed by postnatal transthoracic echography. Treatment with dexamethasone (4 mg/day) was started in the 22nd week of gestation. The outcome was good, with the child remaining asymptomatic 2 years later. This observation describes one of the rare forms of fetal myocarditis with favorable outcome.
De La Villeon
C-G
CG
Cardiologie pédiatrique, hôpital des enfants, CHU de Toulouse, 330, avenue de Grande-Bretagne, 31026 Toulouse cedex 3, France.
Dulac
Y
Y
Ohanessian
G
G
Ziani
A
A
Paranon
S
S
Acar
P
P
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000276:immunology*; D054537:Atrioventricular Block; D001324:Autoantigens / Q000276:immunology*; D002675:Child, Preschool; D003907:Dexamethasone / Q000627:therapeutic use*; D004452:Echocardiography / Q000379:methods; D005260:Female; D005315:Fetal Diseases; D005318:Fetal Heart / Q000000981:diagnostic imaging; D006801:Humans; D009205:Myocarditis / Q000188:drug therapy / Q000196:embryology* / Q000276:immunology; D011247:Pregnancy; D012261:Ribonucleoproteins / Q000276:immunology*; D016896:Treatment Outcome; D000097585:SS-B Antigen
D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D001324:Autoantigens; D003907:Dexamethasone; D012261:Ribonucleoproteins; D000097585:SS-B Antigen; C035356:SS-A antibodies