title: Impact of synchrotron radiation on macromolecular crystallography: a personal view.
abstract: The introduction of synchrotron radiation sources almost four decades ago has led to a revolutionary change in the way that diffraction data from macromolecular crystals are being collected. Here a brief history of the development of methodologies that took advantage of the availability of synchrotron sources are presented, and some personal experiences with the utilization of synchrotrons in the early days are recalled.
authors.affiliation: Synchrotron Radiation Research Section, Macromolecular Crystallography Laboratory, NCI, Argonne National Laboratory, Argonne, IL 60439, USA. zdauter@anl.gov
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Dauter
authors.forename: Mariusz
authors.initials: M
authors.lastname: Jaskolski
authors.forename: Alexander
authors.initials: A
authors.lastname: Wlodawer
mesh_terms: D018360:Crystallography, X-Ray / Q000266:history / Q000379:methods; D005858:Germany; D049673:History, 20th Century; D046911:Macromolecular Substances / Q000737:chemistry*; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D017356:Synchrotrons / Q000266:history; D014481:United States
chemical_list: D046911:Macromolecular Substances; D011506:Proteins