title: beta(1-3)Glucanosyltransferase Gel4p is essential for Aspergillus fumigatus.
abstract: The beta(1-3)glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.
authors.affiliation: Unité des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.
authors.forename: Amandine
authors.initials: A
authors.lastname: Gastebois
authors.forename: Thierry
authors.initials: T
authors.lastname: Fontaine
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Latgé
authors.forename: Isabelle
authors.initials: I
authors.lastname: Mouyna
mesh_terms: D001232:Aspergillus fumigatus / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D002852:Chromatography, Ion Exchange; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D017353:Gene Deletion; D015971:Gene Expression Regulation, Enzymologic; D015966:Gene Expression Regulation, Fungal; D020043:Genes, Essential / Q000235:genetics; D005800:Genes, Fungal / Q000235:genetics; D004693:Glucan Endo-1,3-beta-D-Glucosidase / Q000235:genetics / Q000378:metabolism*; D017261:Glycosylphosphatidylinositols / Q000378:metabolism; D025282:Mycelium / Q000201:enzymology / Q000235:genetics / Q000254:growth & development; D010802:Phylogeny
chemical_list: D005656:Fungal Proteins; D017261:Glycosylphosphatidylinositols; D004693:Glucan Endo-1,3-beta-D-Glucosidase