title: A reversible fluorescent Hg2+ chemosensor based on a receptor composed of a thiol atom and an alkene moiety for living cell fluorescence imaging.
abstract: A novel reversible fluorescence turn-on chemosensor 1 for Hg(2+) was constructed based on a new receptor composed of an S atom and an alkene moiety. The sensor showed a large fluorescence enhancement response (1000-fold enhancement), high selectivity, and high sensitivity with a detection limit of 27.5 nM. Significantly, the reversible sensor functioned well in the near pure aqueous medium and could be employed for Hg(2+) imaging in living cells.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China. weiyinglin@hnu.cn
authors.forename: Weiying
authors.initials: W
authors.lastname: Lin
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Cao
authors.forename: Yundi
authors.initials: Y
authors.lastname: Ding
authors.forename: Lin
authors.initials: L
authors.lastname: Yuan
authors.forename: Quanxing
authors.initials: Q
authors.lastname: Yu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002413:Cations, Divalent / Q000737:chemistry; D005456:Fluorescent Dyes / Q000032:analysis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008628:Mercury / Q000032:analysis* / Q000737:chemistry; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D002413:Cations, Divalent; D005456:Fluorescent Dyes; D013438:Sulfhydryl Compounds; D008628:Mercury