Gold nanoparticle platforms as drug and biomacromolecule delivery systems.
Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/release using these nanocarriers. This review will discuss several delivery strategies utilizing AuNPs.
Duncan
Bradley
B
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Kim
Chaekyu
C
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Rotello
Vincent M
VM
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: rotello@chem.umass.edu.
D000818:Animals; D002463:Cell Membrane Permeability; D002945:Cisplatin / Q000008:administration & dosage; D016503:Drug Delivery Systems; D005978:Glutathione / Q000737:chemistry; D006046:Gold / Q000008:administration & dosage* / Q000737:chemistry; D006801:Humans; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry; D010316:Particle Size; D013499:Surface Properties; D014466:Ultraviolet Rays
D006046:Gold; D005978:Glutathione; D002945:Cisplatin