Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1).
We report a case of atypical hemolytic uremic syndrome (aHUS) triggered by influenza A (H1N1) in a 17-year-old boy with a mutation in the gene (CD46) encoding the transmembrane complement regulator membrane cofactor protein. The patient recovered completely following treatment with oseltamivir, plasma exchange, and hemodialysis. We describe the case and discuss this unusual association of diseases.
Bento
Diogo
D
Intensive Care Unit, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal. diogo_pb@sapo.pt
Mapril
Joana
J
Rocha
Carla
C
Marchbank
Kevin J
KJ
Kavanagh
David
D
Barge
Dawn
D
Strain
Lisa
L
Goodship
Timothy H J
TH
Meneses-Oliveira
Carlos
C
D000293:Adolescent; D006463:Hemolytic-Uremic Syndrome / Q000821:virology*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications*; D008297:Male