title: Ecthyma gangrenosum mimicking acute invasive fungal sinusitis in an immunocompromised patient.
abstract: Ecthyma gangrenosum is a rare necrotizing cutaneous infection usually caused by Pseudomonas aeruginosa. We report a case of ecthyma gangrenosum presenting as a sinonasal eschar and mimicking acute invasive fungal sinusitis in an immunocompromised 39-year-old man with a hematologic malignancy. To the best of our knowledge, this represents the first case of ecthyma gangrenosum affecting the sinonasal mucosa to be reported in the literature.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. AHekiert@entandallergy.com
authors.forename: Adrianna M
authors.initials: AM
authors.lastname: Hekiert
authors.forename: Michael B
authors.initials: MB
authors.lastname: Cohen
authors.forename: Kathleen T
authors.initials: KT
authors.lastname: Montone
authors.forename: James N
authors.initials: JN
authors.lastname: Palmer
authors.forename: Satish
authors.initials: S
authors.lastname: Govindaraj
mesh_terms: D000081:Acetamides / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004473:Ecthyma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D000069349:Linezolid; D008297:Male; D009181:Mycoses / Q000175:diagnosis / Q000382:microbiology; D009297:Nasal Mucosa / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D015242:Ofloxacin / Q000627:therapeutic use; D023303:Oxazolidinones / Q000627:therapeutic use; D011500:Protein Synthesis Inhibitors / Q000627:therapeutic use; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D011550:Pseudomonas aeruginosa; D017511:Pyoderma Gangrenosum; D012307:Risk Factors; D012852:Sinusitis / Q000175:diagnosis* / Q000382:microbiology; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D011500:Protein Synthesis Inhibitors; D014640:Vancomycin; D015242:Ofloxacin; D000069349:Linezolid