title: How to use the computing environment R to analyze ATP-induced ribonucleotide reductase R1 hexamerization data.
abstract: R is an object oriented free and open source statistical computing environment. The R package Combinatorially Complex Equilibrium Model Selection is being developed to meet the analysis challenges of ribonucleotide reductase (RNR). An example of its use is given here. This example involves ATP-induced R1 hexamerization dynamic light scattering data that suggests that R1 hexamers have two types of a-sites, one that binds ATP and another that does not (here, R1 is the large subunit of RNR).
authors.affiliation: Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106, USA. txr24@case.edu
authors.forename: T
authors.initials: T
authors.lastname: Radivoyevitch
mesh_terms: D000255:Adenosine Triphosphate / Q000737:chemistry*; D019295:Computational Biology / Q000379:methods*; D055503:Protein Multimerization; D012264:Ribonucleotide Reductases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D000255:Adenosine Triphosphate; D012264:Ribonucleotide Reductases