In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria.
OBJECTIVE
The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms.


METHODS
The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus planktonic cells and biofilms in vitro.


RESULTS
P aeruginosa, S epidermidis, and S aureus planktonic cells decreased by a mean of 5.10, 4.99, and 5.22 log10 colony-forming units/mL, respectively, with 4 Qoustic Wound Therapy System treatment minutes. After 10 minutes of treatment, P aeruginosa, S epidermidis, and S aureus biofilms decreased by a mean of 1.34, 1.46, and 1.02 log10 colony-forming units/cm, respectively.


CONCLUSIONS
The Qoustic Wound Therapy System, using the Qoustic Qurette, kills planktonic bacteria and reduces bacterial biofilms in vitro.
Karau
Melissa J
MJ
Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Piper
Kerryl E
KE
Steckelberg
James M
JM
Kavros
Steven J
SJ
Patel
Robin
R
D001424:Bacterial Infections / Q000382:microbiology* / Q000628:therapy*; D018441:Biofilms; D015169:Colony Count, Microbial; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000254:growth & development; D013211:Staphylococcus aureus / Q000254:growth & development; D013212:Staphylococcus epidermidis / Q000254:growth & development; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods*; D014945:Wound Healing; D014946:Wound Infection / Q000382:microbiology* / Q000628:therapy*