title: Restorative proctectomy with ileal pouch-anal anastomosis in obese patients.
abstract: OBJECTIVE
  The aim of this study was to assess outcomes of ileal pouch-anal anastomosis in obese patients compared with a matched cohort of nonobese patients.
  
  
  METHODS
  A review of all obese patients who underwent ileal pouch-anal anastomosis from 1998 to 2008 was performed. Obesity was defined as body mass index >or=30 kg/m. A matched control group of patients with body mass index within 18.5 to 25 kg/m was created. Primary end points included operative time, length of hospital stay, operative blood loss, and early (<or=6 wk) and long-term (>6 wk) postoperative complications.
  
  
  RESULTS
  Sixty-five obese patients (mean body mass index, 34.3 +/- 0.51 kg/m) underwent proctectomy with ileal pouch-anal anastomosis or proctocolectomy with ileal pouch-anal anastomosis. Mean body mass index of the control group was 22.45 +/- 0.2 kg/m (P < .0001). The most common diagnosis was mucosal ulcerative colitis (84.6%), followed by familial adenomatous polyposis (13.9%) and Crohn's disease (1.5%). The obese population had a higher incidence of cardiorespiratory comorbidities (P = .044), and a trend for steroid and immunosuppressive therapy (P = .06) preoperatively. Obese patients required longer operative time (P = .001) and longer hospital stay (P = .009). Early postoperative complications were comparable (P > .05). Long-term outcomes were also similar, except for a higher incidence of incisional hernia in the obese group (P = .01).
  
  
  CONCLUSIONS
  The overall postoperative complication rate in obese patients undergoing ileal pouch-anal anastomosis was similar to a matched nonobese cohort of patients. However, longer operative time, longer length of stay, and a higher rate of incisional hernia were noted in the obese population. Obese patients should be appropriately consulted about these issues before undergoing ileal pouch-anal anastomosis.
authors.affiliation: Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA.
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Canedo
authors.forename: Rodrigo A
authors.initials: RA
authors.lastname: Pinto
authors.forename: Elisabeth C
authors.initials: EC
authors.lastname: McLemore
authors.forename: Lester
authors.initials: L
authors.lastname: Rosen
authors.forename: Steven D
authors.initials: SD
authors.lastname: Wexner
mesh_terms: D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D015992:Body Mass Index; D003108:Colonic Diseases / Q000150:complications / Q000601:surgery*; D039021:Colonic Pouches; D005260:Female; D005431:Florida / Q000453:epidemiology; D005500:Follow-Up Studies; D006555:Hernia, Ventral / Q000453:epidemiology; D006801:Humans; D007082:Ileum / Q000601:surgery*; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D016737:Proctocolectomy, Restorative / Q000379:methods*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome