[The role of infection in the development of polypous rhinosinusitis in patients with bronchial asthma].
At present, many authors accept the many-factor theory of development of polypous rhinosinusitis associated with bronchial asthma according to which this condition should be regarded as an inflammatory syndrome in subjects predisposed to a specific tissue reaction. Inflammation induced by an infection is accompanied by the release of protease-inhibiting enzymes that turn inflammation into a chronic process thereby contributing to tissue disintegration, remodeling of mucous membranes, and development of polyps.
Bondarev
G P
GP
Terekhova
A O
AO
D001249:Asthma / Q000150:complications*; D006801:Humans; D009298:Nasal Polyps / Q000201:enzymology / Q000382:microbiology* / Q000821:virology; D012220:Rhinitis / Q000201:enzymology / Q000382:microbiology* / Q000821:virology; D012852:Sinusitis / Q000201:enzymology / Q000382:microbiology* / Q000821:virology