"Alice in Wonderland syndrome" associated with topiramate for migraine prevention.
Various visual and sensory phenomena have been described in migraine with aura. Among those, the 'Alice in Wonderland' syndrome is defined as a distortion of the body image with the patient being aware of its unreal nature. Here, the case of a 17-year-old girl with migraine without aura who developed an 'Alice in Wonderland' syndrome repeatedly on topiramate treatment was presented and potential pathophysiological concepts were discussed.
Jürgens
T P
TP
Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, Germany. t.juergens@uke.de
Ihle
K
K
Stork
J-H
JH
May
A
A
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D001828:Body Image; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006212:Hallucinations / Q000139:chemically induced* / Q000523:psychology; D006801:Humans; D020326:Migraine without Aura / Q000517:prevention & control*; D000077236:Topiramate
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose