title: Pseudolymphomatous tumid lupus erythematosus of the oral mucosa.
abstract: Oral lesions are frequent complications of systemic lupus erythematosus, but only ulceration is included in the 1982 American College of Rheumatology revised criteria. Because the lack of a uniform classification, a range of ulcerative and keratotic lesions are typically described. In this report we describe a unique progressive irregularly cobblestoned and vegetating plaque of the oral mucosa with clinical and histological features mimicking a cutaneous lymphoma. Despite the papillomatous and extensive nature of the lesions and the dense lymphoid infiltrate with follicle formation suggesting a malignant lymphoproliferative process, the slow progression coupled with a mixed cell infiltrate and polyclonality supported a diagnosis of pseudolymphoma. Recognition of this entity is important to prevent diagnosing them as a malignant lymphoma. As well as with the other mucosal lesions in lupus erythematosus, this pseudolymphomatous variant should be added to the disease spectrum.
authors.affiliation: Department of Dermatology, Medical University of Graz, Austria.
authors.forename: Ben
authors.initials: B
authors.lastname: Tallon
authors.forename: Steven
authors.initials: S
authors.lastname: Kaddu
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Cerroni
authors.forename: Helmut
authors.initials: H
authors.lastname: Kerl
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Aberer
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology*; D019310:Pseudolymphoma / Q000209:etiology / Q000473:pathology*