title: [Hyperparathyroidism during pregnancy: dangerous association for the mother and her infant].
abstract: Hypercalcaemia during pregnancy is rare but requires a systematic approach for its diagnosis and its treatment. We report a 32-year-old pregnant female at 32 weeks of gestation who presented a severe hypercalcaemia, due to primary hyperparathyroidism. The delivery allowed the birth of a healthy child who had a serum calcium level in the normal range. Eight days later, the mother was operated from a parathyroid adenoma allowing normalisation of calcaemia. Hyperparathyroidism during pregnancy is rarely reported; it can lead to severe complications for both the mother and the infant. The newborn can present tetania due to hypocalcaemia and hypoparathyroidism can be definitive. Surgery should be discussed when serum calcium level of the mother is markedly elevated.
authors.affiliation: Service d'endocrinologie et maladies métaboliques, HIA Bégin, Saint-Mandé, France. olivierdupuy2@orange.fr
authors.forename: O
authors.initials: O
authors.lastname: Dupuy
authors.forename: P
authors.initials: P
authors.lastname: Aubert
authors.forename: M-L
authors.initials: ML
authors.lastname: Dumuis
authors.forename: L
authors.initials: L
authors.lastname: Bordier
authors.forename: H
authors.initials: H
authors.lastname: Mayaudon
authors.forename: B
authors.initials: B
authors.lastname: Bauduceau
mesh_terms: D000328:Adult; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000150:complications / Q000175:diagnosis*; D007231:Infant, Newborn; D010282:Parathyroid Neoplasms / Q000150:complications / Q000601:surgery*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011263:Pregnancy Trimester, Third; D012016:Reference Values; D016896:Treatment Outcome
chemical_list: D002118:Calcium