title: Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan.
abstract: Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at baseline. When participants were divided into tertiles, all-cause mortality increased significantly as baPWV increased (P<0.001). Participants in the highest baPWV tertile showed an increased risk of all-cause mortality evidenced by a multivariable adjusted hazard ratio of 6.8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population.
authors.affiliation: Department of Health Science, Shiga University of Medical Science, Shiga, Japan. turin@belle.shiga-med.ac.jp
authors.forename: Tanvir Chowdhury
authors.initials: TC
authors.lastname: Turin
authors.forename: Yoshikuni
authors.initials: Y
authors.lastname: Kita
authors.forename: Nahid
authors.initials: N
authors.lastname: Rumana
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Takashima
authors.forename: Aya
authors.initials: A
authors.lastname: Kadota
authors.forename: Kenji
authors.initials: K
authors.lastname: Matsui
authors.forename: Hideki
authors.initials: H
authors.lastname: Sugihara
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Morita
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Miura
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Ueshima
mesh_terms: D000328:Adult; D000368:Aged; D055109:Ankle Brachial Index; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009026:Mortality; D011673:Pulsatile Flow / Q000502:physiology*