title: Periodontitis and cardiovascular disease: Floss and reduce a potential risk factor for CVD.
abstract: There is evidence supporting an association between cardiovascular disease (CVD) and periodontitis. We determined whether patients with chronic periodontitis, who are otherwise healthy individuals, have higher serum concentrations of emerging risk markers of CVD such as C-reactive protein (CRP) and interleukin 6 (IL-6) and investigated the effect of subsequent periodontal treatment on the levels of these markers. A total of 40 individuals were included in the study. Serum levels of CRP and IL-6 were estimated twice, once on the initial visits and the other 3 months after periodontal therapy. The mean CRP and IL-6 levels were significantly higher (P < .001) in the patients compared with controls and significantly decreased (P < .001) following periodontal treatment. This study suggests that periodontitis is a potential modifiable risk factor for CVD.
authors.affiliation: Department of Oral Medicine, Periodontology and Diagnosis, Cairo University, Egypt.
authors.forename: Khaled Abou
authors.initials: KA
authors.lastname: El Fadl
authors.forename: Nivine
authors.initials: N
authors.lastname: Ragy
authors.forename: Mona
authors.initials: M
authors.lastname: El Batran
authors.forename: Neemat
authors.initials: N
authors.lastname: Kassem
authors.forename: Sherine A
authors.initials: SA
authors.lastname: Nasry
authors.forename: Rania
authors.initials: R
authors.lastname: Khalifa
authors.forename: Heba
authors.initials: H
authors.lastname: Sedrak
authors.forename: Esma R
authors.initials: ER
authors.lastname: Isenovic
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology* / Q000517:prevention & control*; D003742:Dental Devices, Home Care; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood / Q000150:complications*; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D002097:C-Reactive Protein