title: [Increased prevalence of depression in hepatitis C infection patients].
abstract: The prevalence of depression is increased in patients with chronic hepatitis C virus (HCV) infection. Several aetiological mechanisms are thought to be involved, e.g. premorbid psychiatric disease, genetic disposition to affective disorders, socio-economic factors, stigmatization and possibly HCV neuroinfection. Evidence to support that former intravenous drug abuse increases the risk of depression is lacking. It is particularly important to diagnose and treat depression in HCV patients as it constitutes a relative contraindication to antiviral treatment and may jeopardize therapeutic outcome.
authors.affiliation: Center for Psykiatrisk Forskning, Arhus Universitetshospital, Risskov, 8240 Risskov, Denmark. bauhjerrild@gmail.com
authors.forename: Simon
authors.initials: S
authors.lastname: Hjerrild
authors.forename: Signe Groth
authors.initials: SG
authors.lastname: Renvillard
authors.forename: Peter Derek Christian
authors.initials: PD
authors.lastname: Leutscher
authors.forename: Poul
authors.initials: P
authors.lastname: Videbech
mesh_terms: D000998:Antiviral Agents; D001921:Brain / Q000821:virology; D000075202:Contraindications; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D020022:Genetic Predisposition to Disease; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000821:virology; D006801:Humans; D001523:Mental Disorders / Q000150:complications; D015995:Prevalence; D012307:Risk Factors
chemical_list: D000998:Antiviral Agents