title: [Influence of vaginal microflora on the presence of persistent atypical squamous cells and atypical glandular cells in pap smear--a 3-year study].
abstract: OBJECTIVE
  the evaluation of influence of abnormal vaginal biocoenosis on presence and maintenance ASC and AGC in Pap smears.
  
  
  METHODS
  The study group consisted of 242 non-pregnant women (25-65 years of age): 207 women (4.96%) with atypical sqamous cells and 35 (0.7%) with atypical glandular cells. In all women the vaginal flora was assessed by Nugent scale.
  
  
  RESULTS
  Vaginal flora was normal in 157 (75.8%) and pathological in 50 (24.1%) women with ASC. In the ASC subgroup, the highest proportion of physiological vaginal flora was observed in 151 patients (77.4%) with ASC-US, in comparison to 44 (22.6%) with ASC-H, in which the percentage of women with normal or abnormal flora was the same (50% vs 50%). This difference was statistically significant. In case of AGC, vaginal culture was physiological in 23 (65.7%) women, and in 12 (34.3%) abnormal vaginal flora with features of the inflammation. The statistically significant influence of abnormal vaginal flora on the presence of atypical endometrial and endocervical cells was not observed.
  
  
  CONCLUSIONS
  We did not observed any influence of abnormal vaginal flora on the presence, regression and progression of ASC and AGC.
authors.affiliation: Klinika Ginekologii i Onkologii Collegium Medicum Uniwersytetu Jagielońskiego w Krakowie. biernat@cm-uj.krakow.pl
authors.forename: Inga
authors.initials: I
authors.lastname: Ludwin
authors.forename: Artur
authors.initials: A
authors.lastname: Ludwin
authors.forename: Antoni
authors.initials: A
authors.lastname: Basta
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002584:Cervix Uteri / Q000473:pathology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D065006:Papanicolaou Test; D011044:Poland; D002583:Uterine Cervical Neoplasms / Q000473:pathology; D014621:Vagina / Q000382:microbiology*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000473:pathology*