title: Duodenal enteroglucagonoma revealed by differential comparison of serum and tissue glucagon reactivity with Siemens' Double Glucagon Antibody and DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon: a case report.
abstract: BACKGROUND
  This case report demonstrates that the differential immunohistochemical reactivities of Siemens' Double Antibody Glucagon compared to DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon allow for pathologic distinction of enteral versus pancreatic glucagonoma.
  
  
  METHODS
  A 64-year-old Caucasian man was diagnosed with a duodenal enteroglucagonoma following presentation with obstructive jaundice. He had a low serum glucagon level using Siemens' Double Antibody Glucagon, a clinical syndrome consistent with glucagon hypersecretion. A periampullary mass biopsy proved to be a neuroendocrine tumor, with positive immunohistochemical reactivity to DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon.
  
  
  CONCLUSIONS
  Differential comparison of the immunohistochemical reactivities of Siemens' Double Antibody Glucagon and DakoCytomation's Polyclonal Rabbit Anti-Human Glucagon discerns enteroglucagon from pancreatic glucagon.
authors.affiliation: Department of Surgery, Division of Transplant Surgery and Hepatobiliary Surgery, Henry Ford Hospital, West Grand Boulevard (CFP-2), Detroit, MI 48202, USA. blakevanderlan@yahoo.com.
authors.forename: Wesley B
authors.initials: WB
authors.lastname: Vanderlan
authors.forename: Ziying
authors.initials: Z
authors.lastname: Zhang
authors.forename: Marwan S
authors.initials: MS
authors.lastname: Abouljoud