Pd(OAc)2-catalyzed regioselective arylation of indoles with arylsiloxane in acidic medium.
Mild conditions have been developed to achieve a Pd(OAc)(2)-catalyzed cross-coupling between indoles and arylsiloxanes in the presence of TBAF and Ag(2)O in acidic medium. Electron-deficient arylsiloxanes presented high efficiency in this system to give the arylated indoles in excellent yields.
Liang
Zunjun
Z
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
Yao
Bangben
B
Zhang
Yuhong
Y