title: [Clinical outcome of partial glossectomy or brachytherapy in early-stage tongue cancer].
abstract: Partial glossectomy and low-dose-rate (LDR) brachytherapy are both effective in early-stage tongue cancer without lymph node metastasis, although head and neck surgeons and radiation oncologists disagree on which treatment is superior. Because our subjects select the treatment modality, we compared treatment results between 39 subjects undergoing partial glossectomy and 107 undergoing brachytherapy for stage I/II tongue cancer. Local recurrence was observed in 10% and cervical lymph node recurrence in 23% following partial glossectomy, versus local recurrence in 13% and cervical lymph node recurrence in 24% following brachytherapy. Disease-free 5-year survival was 87.0% following partial glossectomy and 90.7% following brachytherapy. Because incidence of local recurrence, nodal metastasis, and prognosis were the same regardless of treatment modality, treatment should be based on the age, performance status, and quality of life among subjects.
authors.affiliation: Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka.
authors.forename: Torahiko
authors.initials: T
authors.lastname: Nakashima
authors.forename: Katsumasa
authors.initials: K
authors.lastname: Nakamura
authors.forename: Hideki
authors.initials: H
authors.lastname: Shiratsuchi
authors.forename: Ryuji
authors.initials: R
authors.lastname: Yasumatsu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Toh
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Shioyama
authors.forename: Shizuo
authors.initials: S
authors.lastname: Komune
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D018572:Disease-Free Survival; D005260:Female; D005927:Glossectomy / Q000379:methods*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D014062:Tongue Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D016896:Treatment Outcome