[Fibromyalgia as a neuropathic pain condition].
Fibromyalgia is characterised by chronic widespread pain and mechanical hyperalgesia. It is associated with a higher pain intensity, fewer pain-free intervals and more pronounced pain-related interference in function than other musculoskeletal pain conditions. Increasing evidence supports an underlying augmented central pain processing which includes sensitization of pain-transmitting neurons and dysfunction of pain inhibitory pathways. If this permanent change in the function of the nociceptive system is shown to equal fibromyalgia, the condition may be considered a neuropathic pain condition.
Amris
Kirstine
K
Parker Instituttet og Reumatologisk Afdeling H, Frederiksberg Hospital, 2000 Frederiksberg, Denmark. kirstine.amris@frh.regionh.dk
Jespersen
Anders
A
D015415:Biomarkers / Q000134:cerebrospinal fluid; D001921:Brain / Q000503:physiopathology; D005356:Fibromyalgia / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D006930:Hyperalgesia / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009437:Neuralgia / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D009619:Nociceptors / Q000502:physiology
D015415:Biomarkers