title: Synthesis of chiral cyclobutane containing C3-symmetric peptide dendrimers.
abstract: Five new highly functionalized cyclobutane containing C(3)-symmetric peptide dendrimers have been synthesized through a convergent approach from 1,3,5-trisubstituted benzene and chiral gamma,epsilon-amino diacid derivatives as well as a gamma-tetrapeptide. The first example of the synthesis of N-centered amides by using 1,3,5-triaminobenzene and a carboxylic acid is reported.
authors.affiliation: Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
authors.forename: Raquel
authors.initials: R
authors.lastname: Gutiérrez-Abad
authors.forename: Ona
authors.initials: O
authors.lastname: Illa
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Ortuño
mesh_terms: D001554:Benzene / Q000737:chemistry*; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D050091:Dendrimers; D010455:Peptides; D001554:Benzene