title: Pigmented deposits on a Boston keratoprosthesis from topical ibopamine.
abstract: OBJECTIVE
  To report a case of pigmented deposits on a type I Boston keratoprosthesis (KPro) associated with the use of topical ibopamine as a treatment for hypotony.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  The dopamine-like agent ibopamine caused black deposits on the bandage lens and on the front plate of the Boston KPro that resulted in reduced visual acuity. Change to a daily disposable contact lens and regular cleaning of the KPro front plate with diluted baby shampoo eliminated this problem.
  
  
  CONCLUSIONS
  This is the first report of this complication with topical ibopamine use and should be considered when ibopamine is used chronically for hypotony.
authors.affiliation: Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
authors.forename: Justin M
authors.initials: JM
authors.lastname: Kanoff
authors.forename: Kathryn
authors.initials: K
authors.lastname: Colby
mesh_terms: D000287:Administration, Topical; D001187:Artificial Organs; D003846:Deoxyepinephrine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D018491:Dopamine Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008543:Melanins / Q000737:chemistry; D008548:Melanosis / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D015814:Ocular Hypotension / Q000188:drug therapy; D019736:Prostheses and Implants; D011475:Prosthesis Failure
chemical_list: D018491:Dopamine Agonists; D008543:Melanins; C023487:ibopamine; D003846:Deoxyepinephrine