A radical-based approach to hydroxytetralones from unprotected phenols.
Xanthates derived from unprotected 2-hydroxyacetophenones undergo smooth intermolecular addition to unactivated alkenes and subsequent cyclisation to give hydroxytetralones in good yield.
Petit
Laurent
L
Laboratoire de Synthèse Organique associé au C.N.R.S., Département de Chimie, Ecole Polytechnique, F-91128 Palaiseau, France.
Zard
Samir Z
SZ