title: Explained factors of suicide attempts in major depression.
abstract: OBJECTIVE
  The aim of this study is to identify risk factors for suicide attempts including bipolarity.
  
  
  METHODS
  The paper presents the most recent data on suicide attempts and depression with or without hypomanic features from three French "Bipolact", studies including 2249 patients with recurrent or resistant depression. Hypomania and BP-II disorder were defined by a score of 10 or more on the Hypomania Checklist-20. Attempters and non-attempters were compared, and multivariate logistic regression analyses were performed on all the significant variables obtained in univariate tests.
  
  
  RESULTS
  Rates of suicide attempts and of a family history of suicide were higher in BP-II disorder. Suicide attempts were best explained by a family history of suicide and mood disorders, recurrence of depression, the "irritable-risk-taking" dimension of hypomania, substance abuse, and need of psychiatric treatment.
  
  
  CONCLUSIONS
  The study does not deal with DSM-IV BP-II disorder.
  
  
  CONCLUSIONS
  Clinicians need to be familiarized with these risk factors.
authors.affiliation: Anxiety and Mood Center, CTAH, 117 rue de Rennes, Paris, France. elie.hantouche@wanadoo.fr
authors.forename: Elie
authors.initials: E
authors.lastname: Hantouche
authors.forename: Jules
authors.initials: J
authors.lastname: Angst
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Azorin
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics / Q000523:psychology*; D057189:Checklist; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000235:genetics / Q000523:psychology*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory / Q000706:statistics & numerical data; D012008:Recurrence; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000235:genetics / Q000523:psychology; D013406:Suicide, Attempted / Q000523:psychology*