[Beneficial action of the liposomal form of dihydroquercetin on the process of skin regeneration after thermal burn].
It was found that the flavonoid of plant origin, dihydroquercetin, being localized in lecitin nanoparticles in the presence of amino acid, reduced inflammatory reactions in the wound zone after thermal burn. Application of the liposomal complex on burn trauma stabilized the endogenous antioxidant system and minimized the area of the secondary necrosis in burn wound. Also, intensification of skin regeneration and repair of hair follicles and sebaceous glands were observed.
Naumov
A A
AA
Potselueva
M M
MM
D000287:Administration, Topical; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism; D002056:Burns / Q000188:drug therapy* / Q000473:pathology; D005419:Flavonoids / Q000008:administration & dosage*; D008081:Liposomes; D008297:Male; D011794:Quercetin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D014945:Wound Healing / Q000187:drug effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D005419:Flavonoids; D008081:Liposomes; D011794:Quercetin; C003377:taxifolin