title: Successful salvage of kidney allografts threatened by ureteral stricture using pyelovesical bypass.
abstract: Ureteral stricture is the most common urologic complication after renal transplantation. When endourologic management fails, open ureteral reconstruction remains the standard treatment. The complexity of some of these procedures makes it necessary to explore other means of repair. This study evaluated the intermediate-term outcome of subcutaneous pyelovesical bypass graft (SPBG) on renal transplant recipients. We reviewed 8 patients (6 male and 2 female; mean age 52 years) with refractory ureteral strictures postrenal transplantation, who received SPBG as salvage therapy. All patients failed endourologic management and half failed open management of their strictures. After a mean follow-up of 19.4 months, 7 out of 8 renal grafts have good function with mean GFR of 58.5 mL/min/1.73 m(2), without evidence of obstruction or infection. One patient lost his graft due to persistent infection of the SPBG and one patient developed a recurrent urinary tract infection managed with long-term antibiotics. SPBG offers a last resort in the treatment of ureteral stricture after renal transplantation refractory to conventional therapy.
authors.affiliation: Department of Urology, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: R A
authors.initials: RA
authors.lastname: Azhar
authors.forename: M
authors.initials: M
authors.lastname: Hassanain
authors.forename: M
authors.initials: M
authors.lastname: Aljiffry
authors.forename: S
authors.initials: S
authors.lastname: Aldousari
authors.forename: T
authors.initials: T
authors.lastname: Cabrera
authors.forename: S
authors.initials: S
authors.lastname: Andonian
authors.forename: P
authors.initials: P
authors.lastname: Metrakos
authors.forename: M
authors.initials: M
authors.lastname: Anidjar
authors.forename: S
authors.initials: S
authors.lastname: Paraskevas
mesh_terms: D000328:Adult; D000368:Aged; D003251:Constriction, Pathologic / Q000150:complications / Q000209:etiology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014513:Ureter / Q000601:surgery*; D014517:Ureteral Obstruction / Q000209:etiology / Q000601:surgery / Q000628:therapy; D014656:Vascular Surgical Procedures / Q000009:adverse effects