Topical treatment of psoriasis.
BACKGROUND
The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit. Optimal use of topical therapy requires an awareness of the range and efficacy of all products.


METHODS
The review covers the efficacy and role of topical therapies including emollients, corticosteroids, vitamin D analogs, calcineurin inhibitors, dithranol, coal tar, retinoids, keratolyics and combination therapy. The report was prepared following a PubMed and Embase literature search up to April 2010.


RESULTS
The paper provides a broad review of the relevant topical therapeutic options available in routine clinical practice for the management of psoriasis and a recommendation for selection of treatment.


CONCLUSIONS
Topical therapies used appropriately provide a safe and effective option for the management of psoriasis. An awareness of the available products and their efficacy is key to treatment selection and patient satisfaction.
Laws
Philip M
PM
The University of Manchester, Salford Royal Hospital (Hope), Manchester Academic Health Sciences Centre, Department of Dermatology, Salford, Manchester M6 8HD, UK.
Young
Helen S
HS
D000287:Administration, Topical; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011565:Psoriasis / Q000188:drug therapy*; D018570:Risk Assessment; D016896:Treatment Outcome
D003879:Dermatologic Agents