Synthesis and Characterization of Shape Memory (Meth)Acrylate Co-Polymers and their Cytocompatibility In Vitro.
A series of novel transparent shape memory co-polymers, made from (meth)acrylate monomers, intended to be used as intraocular lens, was synthesized. The thermo-mechanical properties, shape memory properties and optical properties of the co-polymers could be adjusted by using monomers with various alkyl chain lengths. The cytocompatibility of the prepared co-polymers to L929 mouse connective tissue fibroblasts was demonstrated in vitro, and the co-polymers exhibited favorable cytocompatibility, supporting cell viability and proliferation. This study showed that the prepared co-polymers, which exhibited good flexibility, adjustable shape memory properties, high transparency and favorable cytocompatibility, could find great promising applications as intraocular lens.
Song
Li
L
a School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China.
Hu
Wang
W
Wang
Guojie
G
Zhang
Hongbin
H
Niu
Guoguang
G
Cao
Hui
H
Yang
Huai
H
Zhu
Siquan
S
D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D066241:Carbon-13 Magnetic Resonance Spectroscopy; D002460:Cell Line; D049109:Cell Proliferation / Q000502:physiology; D002470:Cell Survival / Q000502:physiology; D005347:Fibroblasts / Q000502:physiology; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D051379:Mice; D020273:Orbital Implants; D018583:Pliability; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D011474:Prosthesis Design; D017550:Spectroscopy, Fourier Transform Infrared
D001672:Biocompatible Materials; D008689:Methacrylates; D011108:Polymers