Contribution of glutathione and MRP-mediated efflux to intracellular oxaliplatin accumulation.
Mohn
C
C
Institute of Pharmacy, Department of Clinical Pharmacy, University of Bonn, Bonn, Germany.
Kalayda
G V
GV
Häcker
H-G
HG
Gütschow
M
M
Metzger
S
S
Jaehde
U
U
D000970:Antineoplastic Agents / Q000493:pharmacokinetics*; D045744:Cell Line, Tumor; D005978:Glutathione / Q000378:metabolism*; D006801:Humans; D000089762:Multidrug Resistance-Associated Protein 2; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000502:physiology*; D009944:Organoplatinum Compounds / Q000493:pharmacokinetics*; D000077150:Oxaliplatin
D000970:Antineoplastic Agents; D005978:Glutathione; D000089762:Multidrug Resistance-Associated Protein 2; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; C421109:multidrug resistance-associated protein 1