title: Activated sludge behaviour in a batch reactor in the presence of antibiotics: study of extracellular polymeric substances.
abstract: The influence of Erythromycin, Roxithromycin, Amoxicillin, Tetracycline and Sulfamethoxazole on municipal sludge in batch reactors was investigated. The study was focused on extracellular polymeric substances (EPS) as indicator of bacteria sensitivity to toxic agents. The EPS were analysed by UV-Vis and FT-IR spectroscopies and by size exclusion chromatography. It was found that Erythromycin and Roxithromycin induced a significant increase of bound EPS in flocs. This was attributed to a protection mechanism of the bacteria. Erythromycin was the only antibiotic which inhibited COD and nitrogen removal.
authors.affiliation: Laboratoire Environnement et Minéralurgie, Nancy-Université, LEM UMR CNRS INPL 7569, 15 avenue du Charmois, 54500 Vandoeuvre-les-Nancy, France. catalina.avella@ensg.inpl-nancy.fr
authors.forename: A C
authors.initials: AC
authors.lastname: Avella
authors.forename: M
authors.initials: M
authors.lastname: Essendoubi
authors.forename: J N
authors.initials: JN
authors.lastname: Louvet
authors.forename: T
authors.initials: T
authors.lastname: Görner
authors.forename: G D
authors.initials: GD
authors.lastname: Sockalingum
authors.forename: M N
authors.initials: MN
authors.lastname: Pons
authors.forename: M
authors.initials: M
authors.lastname: Manfait
authors.forename: P H
authors.initials: PH
authors.lastname: de Donato
mesh_terms: D000658:Amoxicillin / Q000032:analysis; D000900:Anti-Bacterial Agents / Q000032:analysis*; D019149:Bioreactors; D002850:Chromatography, Gel; D004917:Erythromycin / Q000032:analysis; D009584:Nitrogen / Q000302:isolation & purification; D011108:Polymers; D015575:Roxithromycin / Q000032:analysis; D012722:Sewage / Q000032:analysis*; D013053:Spectrophotometry; D013055:Spectrophotometry, Infrared; D013420:Sulfamethoxazole / Q000032:analysis; D013752:Tetracycline / Q000032:analysis
chemical_list: D000900:Anti-Bacterial Agents; D011108:Polymers; D012722:Sewage; D015575:Roxithromycin; D004917:Erythromycin; D000658:Amoxicillin; D013752:Tetracycline; D013420:Sulfamethoxazole; D009584:Nitrogen