title: Seroprevalence of HTLV-1 among kidney graft recipients: a single-center study.
abstract: BACKGROUND
  Renal transplant recipients are susceptible to viral infections because of their immunocompromised background. HTLV-1 is a retrovirus that leads to adult T-cell leukemia/lymphoma or myelopathies. This study aimed to evaluate HTLV-1 antibodies among renal transplant recipients in Urmia, Iran.
  
  
  METHODS
  Serum samples of 91 renal transplant recipients from Urmia, Iran, were examined serologically for antibodies against HTLV type 1 using an enzyme-linked immunosorbent assay.
  
  
  RESULTS
  Mean age was 37.26 +/- 14.22 years old. Only 1 patient had a positive anti-HTLV-1 enzyme-linked immunosorbent assay test, which was confirmed by Western blot. The HTLV-1-positive case did not have HTLV-associated clinical manifestation. This patient was a 45-year-old man, with no history of blood transfusion, but he did have a history of hemodialysis before transplant.
  
  
  CONCLUSIONS
  The frequency of HTLV-1 among renal transplant recipients of our region in the northwest of Iran was not so high, and it is similar to the HTLV- 1 seroprevalence among hemodialysis patients. Still, it is more frequent among healthy blood donors as representative of the general population in our region.
authors.affiliation: Department of Microbiology and Immunology, Umria University of Medical Sciences, Urmia, Iran.
authors.forename: Zakieh Rostamzadeh
authors.initials: ZR
authors.lastname: Khameneh
authors.forename: Nariman
authors.initials: N
authors.lastname: Sepehrvand
authors.forename: Sima
authors.initials: S
authors.lastname: Masudi
authors.forename: Ali
authors.initials: A
authors.lastname: Taghizade-Afshari
mesh_terms: D000328:Adult; D015153:Blotting, Western; D003430:Cross-Sectional Studies; D006800:Deltaretrovirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood*; D015368:Human T-lymphotropic virus 1 / Q000276:immunology*; D006801:Humans; D007492:Iran / Q000453:epidemiology; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D015481:HTLV-I Antibodies