title: Treatment of allergic rhinitis.
abstract: Allergic rhinitis is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma. Treatment should be based on the patient's age and severity of symptoms. Patients should be advised to avoid known allergens and be educated about their condition. Intranasal corticosteroids are the most effective treatment and should be first-line therapy for mild to moderate disease. Moderate to severe disease not responsive to intranasal corticosteroids should be treated with second-line therapies, including antihistamines, decongestants, cromolyn, leukotriene receptor antagonists, and nonpharmacologic therapies (e.g., nasal irrigation). With the exception of cetirizine, second-generation antihistamines are less likely to cause sedation and impair performance. Immunotherapy should be considered in patients with a less than adequate response to usual treatments. Evidence does not support the use of mite-proof impermeable covers, air filtration systems, or delayed exposure to solid foods in infancy.
authors.affiliation: University of California, Los Angeles, USA. dsur@mednet.ucla.edu
authors.forename: Denise K
authors.initials: DK
authors.lastname: Sur
authors.forename: Stephanie
authors.initials: S
authors.lastname: Scandale
mesh_terms: D000281:Administration, Intranasal; D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D004205:Cromolyn Sodium / Q000009:adverse effects / Q000627:therapeutic use; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D014663:Nasal Decongestants / Q000008:administration & dosage / Q000627:therapeutic use; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D006633:Histamine Antagonists; D014663:Nasal Decongestants; D004205:Cromolyn Sodium