title: Variable phenotypes of bicuspid aortic valve disease: classification by cardiovascular magnetic resonance.
abstract: BACKGROUND
  Recently, cardiovascular magnetic resonance (CMR) has been shown to allow accurate visualisation and quantification of aortic valve disease. Although bicuspid aortic valve (BAV) disease is relatively rare in the general population, the frequency is high in patients requiring valve surgery. The aim of the current study was to characterise the different phenotypes of BAV disease by CMR.
  
  
  METHODS
  CMR studies were performed on a 1.5 T scanner in 105 patients with BAV.
  
  
  RESULTS
  The pattern of BAV phenotypes was as follows: a raphe was identified in 90 patients (86%). Among patients with raphe, 76 patients had fusion between the right and left cusps (RL) and 14 patients had fusion between the right and the non-coronary cusps (RN). There were no significant differences in the aortic dimensions in the different BAV phenotypes.
  
  
  CONCLUSIONS
  CMR allows excellent characterisation of valve phenotype in patients with BAV. The present data demonstrate that a raphe is present in the vast majority of cases and RL fusion is the predominant phenotype of BAV. No significant differences in the aortic dimensions were observed.
authors.affiliation: Klinik und Poliklinik für Innere Medizin II, Universitätsklinikum Regensburg, Regensburg, Germany. stefan.buchner@klinik.uni-regensburg.de
authors.forename: Stefan
authors.initials: S
authors.lastname: Buchner
authors.forename: Marion
authors.initials: M
authors.lastname: Hülsmann
authors.forename: Florian
authors.initials: F
authors.lastname: Poschenrieder
authors.forename: Okka W
authors.initials: OW
authors.lastname: Hamer
authors.forename: Claudia
authors.initials: C
authors.lastname: Fellner
authors.forename: Reinhard
authors.initials: R
authors.lastname: Kobuch
authors.forename: Stefan
authors.initials: S
authors.lastname: Feuerbach
authors.forename: Günter A J
authors.initials: GA
authors.lastname: Riegger
authors.forename: Behrus
authors.initials: B
authors.lastname: Djavidani
authors.forename: Andreas
authors.initials: A
authors.lastname: Luchner
authors.forename: Kurt
authors.initials: K
authors.lastname: Debl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001011:Aorta / Q000473:pathology; D001021:Aortic Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D017548:Echocardiography, Transesophageal; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010641:Phenotype; D015203:Reproducibility of Results; D012189:Retrospective Studies; D055815:Young Adult