En plaque meningioma with angioinvasion.
En plaque meningioma is a rare type of meningioma characterized by infiltrative nature, sheet-like growth and at times invading the bone. We report here a case of en plaque meningioma with typical grade I histomorphology along with unusual feature of angioinvasion. The patient was a 55-year-old man presenting with headache and painful proptosis of right eye. Imaging modalities revealed an en -plaque meningioma extending into the right sylvian fissure, with thickening of right temporal calvarium, greater wing of sphenoid and extension into the orbit. Magnetic resonance angiography showed medial displacement of right middle cerebral artery. The tumor was removed from the sylvian fissure and right temporal convexity. However, only subtotal removal of the intraorbital part was possible. Histology showed a meningothelial meningioma with low tumor cell proliferation, but infiltration into the bone, skeletal muscle and angioinvasion. Recognition of meningiomas en plaque is useful, as these tumors are difficult to resect completely, and are more prone to undergo recurrence or malignant change. In addition, angioinvasion seen in this tumor may have additional prognostic significance.
Basu
Keya
K
Department of Pathology, Nilratan Sirkar Medical College, Kolkata, India.
Majumdar
Kaushik
K
Chatterjee
Uttara
U
Ganguli
Manojit
M
Chatterjee
Sandip
S
D000792:Angiography; D001921:Brain / Q000000981:diagnostic imaging; D005094:Exophthalmos / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008853:Microscopy; D008875:Middle Aged; D009389:Neovascularization, Pathologic