An alkynylboronate cycloaddition strategy to functionalised benzyne derivatives.
A new approach to benzyne precursors has been developed that involves the [4+2] cycloaddition of trimethylsilyl alkynylboronates with 2-pyrones, followed by oxidation and trifluoromethylsulfonylation of the boronate moiety.
Kirkham
James D
JD
Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.
Delaney
Patrick M
PM
Ellames
George J
GJ
Row
Eleanor C
EC
Harrity
Joseph P A
JP
D001555:Benzene Derivatives / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D003500:Cyclization; D010084:Oxidation-Reduction; D011753:Pyrones / Q000737:chemistry
D001555:Benzene Derivatives; D001897:Boronic Acids; D011753:Pyrones; C524146:benzyne