[Clinical efficiency of the use of interferon inductors in surgical patients].
The authors describe their experience in using cycloferon in 27 patients with pyoseptic abdominal pathology. For comparative evaluation of the efficacy of the immunomodulator, they examined 34 patients who received conventional drug therapy. Immunomodulatory therapy was performed, by taking into account the data on the immune status and severity rated by the SIRS and SAPS. Indications for immunomodulatory therapy were defined. The results of immunomodulation suggest that the use of cycloferon in the complex therapy of patients with pyoseptic abdominal diseases makes it possible to enhance the efficiency of treatment and to reduce the number of postoperative complications.
Stupin
V A
VA
Givirovskaia
N E
NE
Zhidkikh
N V
NV
D034841:Abdominal Cavity / Q000382:microbiology*; D000166:Acridines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D056747:Immunomodulation; D007369:Interferon Inducers / Q000627:therapeutic use*; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology*; D018805:Sepsis / Q000188:drug therapy*; D013492:Suppuration / Q000188:drug therapy; D016896:Treatment Outcome
D000166:Acridines; D007369:Interferon Inducers; C026430:10-carboxymethyl-9-acridanone