Contaminated heparin-affected patient plasmas are associated with activated contact systems.
Yi Qian
Department of Pathology, Washington University School of Medicine, St Louis, MO 63110, USA.
Jing Pan
Xiaodong Zhou
Weiser
Peter
P
Hong Lu
Beck
Anne M
AM
Shih
Fei F
FF
Lijuan Zhang
D000707:Anaphylaxis / Q000097:blood / Q000139:chemically induced*; D000925:Anticoagulants / Q000032:analysis / Q000494:pharmacology* / Q000627:therapeutic use; D001777:Blood Coagulation / Q000187:drug effects*; D002809:Chondroitin Sulfates / Q000009:adverse effects* / Q000032:analysis / Q000494:pharmacology; D003174:Complement C1 Inactivator Proteins / Q000032:analysis; D050718:Complement C1 Inhibitor Protein; D003289:Convalescence; D004340:Drug Contamination; D004789:Enzyme Activation / Q000187:drug effects; D006493:Heparin / Q000032:analysis / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007610:Kallikreins / Q000502:physiology; D007704:Kininogens / Q000097:blood; D015539:Platelet Activation / Q000187:drug effects; D011288:Prekallikrein / Q000032:analysis / Q000187:drug effects / Q000378:metabolism; D011516:Prothrombin / Q000378:metabolism; D006435:Renal Dialysis; D013917:Thrombin / Q000096:biosynthesis; D013921:Thrombocytopenia / Q000139:chemically induced*
D000925:Anticoagulants; D003174:Complement C1 Inactivator Proteins; D050718:Complement C1 Inhibitor Protein; D007704:Kininogens; C469952:SERPING1 protein, human; D011516:Prothrombin; D006493:Heparin; D002809:Chondroitin Sulfates; D011288:Prekallikrein; D007610:Kallikreins; D013917:Thrombin