title: Sodium tetradecyl sulphate direct intralesional sclerotherapy of venous malformations of the vulva and vagina: report of five cases.
abstract: We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control.
authors.affiliation: Department of Radiology, Guy's and St. Thomas' NHS Trust, London, UK. mkrokidis@hotmail.com
authors.forename: Miltiadis
authors.initials: M
authors.lastname: Krokidis
authors.forename: Pietro
authors.initials: P
authors.lastname: Venetucci
authors.forename: Adam
authors.initials: A
authors.lastname: Hatzidakis
authors.forename: Vittorio
authors.initials: V
authors.lastname: Iaccarino
mesh_terms: D000293:Adolescent; D005260:Female; D005471:Fluoroscopy; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D010690:Phlebography; D012597:Sclerosing Solutions; D015911:Sclerotherapy / Q000379:methods*; D012981:Sodium Tetradecyl Sulfate / Q000008:administration & dosage*; D014621:Vagina / Q000098:blood supply*; D054079:Vascular Malformations / Q000628:therapy*; D014680:Veins / Q000002:abnormalities*; D014844:Vulva / Q000098:blood supply*; D055815:Young Adult
chemical_list: D012597:Sclerosing Solutions; D012981:Sodium Tetradecyl Sulfate