Carboxylation of C-H bonds using N-heterocyclic carbene gold(I) complexes.
A highly efficient [(NHC)Au(I)]-based (NHC = N-heterocyclic carbene) catalytic system for the carboxylation of aromatic and heteroaromatic C-H bonds was developed. The significant base strength of the Au-OH species is at the origin of the activation process and permits the facile functionalization of C-H bonds without the use of other organometallic reagents.
Boogaerts
Ine I F
II
EaStCHEM School of Chemistry, University of St Andrews, St. Andrews KY16 9ST, UK.
Nolan
Steven P
SP