[The composition, biochemical properties and toxicity of snake venoms].
2.5 million cases of snake bites are noticed in the world every year (within 100,000 is mortal). These bites occur frequently in Asia and Africa. Some reports proved the toxicity and composition changes of well-known venoms from the same snake species according to the climatic zone. Snake venom is a natural source of many biologically active substances, including those with potential therapeutic properties. These substances contain peptides, proteins, and enzymes which are divided into five subfamilies: three-finger toxins, serine protease inhibitors of the Kunitz type, phospholipases A2, serine proteases, and metalloproteases. All snake venoms are grouped depending on their mode of action. They usually cause neurotransmission disorders, cardiotoxic action, hemostasis disorders, and have central nervous system and necrotic activity.
Całkosiński
Ireneusz
I
Katedra i Zakład Biochemii Lekarskiej, Akademia Medyczna we Wrocławiu, Wrocław. i.calkosinski@wp.pl
Seweryn
Ewa
E
Zasadowski
Arkadiusz
A
Małolepsza-Jarmołowska
Katarzyna
K
Dzierzba
Katarzyna
K
Bronowicka-Szydełko
Agnieszka
A
Mierzchała
Magdalena
M
Ceremuga
Ireneusz
I
Rosińczuk-Tonderys
Joanna
J
Dobrzyński
Maciej
M
Gamian
Andrzej
A
D000818:Animals; D006801:Humans; D012910:Snake Venoms / Q000737:chemistry* / Q000494:pharmacology / Q000633:toxicity*
D012910:Snake Venoms