Association of adenoid surface biofilm formation and chronic otitis media with effusion.
OBJECTIVE
To investigate bacterial biofilm formation on the adenoid surface of pediatric patients undergoing adenoidectomy and to reveal whether this formation is associated with chronic otitis media with effusion (COME).


METHODS
Prospective, single-blinded study with scanning electron microscopy.


METHODS
Dişkapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey.


METHODS
Thirty-four children between 4 and 15 years of age (mean age, 7.76 years) who had undergone adenoidectomy from June 1 through December 31, 2007, were divided into 2 groups. The first group (17 children) had undergone adenoidectomy alone, whereas the second group (17 children) had undergone adenoidectomy combined with ventilation tube insertion for COME.


METHODS
Scanning electron microscopy was performed to observe biofilm formation on the surface of adenoid tissues. The biofilm formation was graded according to extension. The roles of adenoid size, age, sex, and duration of COME symptoms were evaluated.


RESULTS
Biofilm formation was detected on all samples. Adenoids removed from patients with COME had higher-grade biofilm formation than the other group (P = .001). No correlation was found between adenoid size and biofilm formation.


CONCLUSIONS
In pediatric patients, adenoid surface biofilm formation may be associated with COME etiopathogenesis.
Saylam
Güleser
G
Kizilirmak Mah 53.Cad 35/10, 06520-Cukurambar Ankara, Turkey. guleserkilic@yahoo.com
Tatar
Emel Cadalli
EC
Tatar
Ilkan
I
Ozdek
Ali
A
Korkmaz
Hakan
H
D000233:Adenoidectomy; D000234:Adenoids / Q000382:microbiology* / Q000473:pathology; D000293:Adolescent; D018441:Biofilms; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D010034:Otitis Media with Effusion / Q000209:etiology*; D011446:Prospective Studies