title: Statistically deformable 2D/3D registration for estimating post-operative cup orientation from a single standard AP X-ray radiograph.
abstract: The widely used procedure of estimating post-operative cup orientation based on a single standard AP X-ray radiograph is known inaccurate, largely due to the wide variability in individual pelvic orientation relative to X-ray plate. CT-based 2D/3D rigid image registration methods have been developed to measure post-operative cup orientation. Although encouraging results have been reported, their extensive usage in clinical routine is still limited. This may be explained by their requirement of having a CT study of the patient at some point during treatment, which is not available for vast majority of Total Hip Arthroplasty procedures performed nowadays. To address this limitation, this article proposes a statistically deformable 2D/3D registration approach for estimating post-operative cup orientation. No CT study of the patient is required any more. Compared to ground truths established from post-operative CT images, the cup orientations measured by the present technique in a cadaver experiment showed differences of 1.7 +/- 1.4 degrees for anteversion and difference of 1.5 +/- 1.5 degrees for inclination. When the present technique was evaluated on patients' datasets, differences of 2.2 +/- 1.3 degrees and differences of 2.0 +/- 0.8 degrees were found for the anteversion and the inclination, respectively. The experimental results, though still preliminary, demonstrated the efficacy of the present approach.
authors.affiliation: Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland. guoyan.zheng@ieee.org
authors.forename: Guoyan
authors.initials: G
authors.lastname: Zheng
mesh_terms: D000077:Acetabulum / Q000000981:diagnostic imaging*; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*