Manipulation of host membrane machinery by bacterial pathogens.
Subversion of host membrane machinery is important for the uptake, survival, and replication of bacterial pathogens. Understanding how pathogens manipulate host membrane transport pathways provides mechanistic insight into how infection occurs and is also revealing new information on biochemical processes involved in the functioning of eukaryotic cells. In this review we discuss several of the canonical host pathways targeted by bacterial pathogens and emerging areas of investigation in this exciting field.
Cossart
Pascale
P
Unité des Interactions Bactéries-Cellules, Institut Pasteur, F-75015 Paris, France. pcossart@pasteur.fr
Roy
Craig R
CR
D000818:Animals; D001343:Autophagy / Q000502:physiology; D001419:Bacteria / Q000378:metabolism*; D001422:Bacterial Adhesion / Q000502:physiology; D002462:Cell Membrane / Q000382:microbiology*; D054884:Host-Pathogen Interactions; D006801:Humans; D014617:Vacuoles / Q000382:microbiology