title: Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) isolates from Korea.
abstract: Emergence of Candida haemulonii and closely related species at five Korean hospitals has been recently described. We examined biofilm formation by these isolates and assessed their genotypic relatedness by pulsed-field gel electrophoresis (PFGE). This study is the first to show that all bloodstream isolates of Candida pseudohaemulonii can form significant biofilms in glucose-containing medium. PFGE of NotI-digested genomic DNA revealed that C. pseudohaemulonii isolates recovered from seven patients in two hospitals shared five patterns, and that 15 isolates of a proposed new species (Candida auris) obtained from patients at three hospitals shared seven patterns, suggesting that some of these isolates may be related to clonal transmission.
authors.affiliation: Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
authors.forename: Bong Joon
authors.initials: BJ
authors.lastname: Oh
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Mi-Na
authors.initials: MN
authors.lastname: Kim
authors.forename: Heungsup
authors.initials: H
authors.lastname: Sung
authors.forename: Kyungwon
authors.initials: K
authors.lastname: Lee
authors.forename: Min Young
authors.initials: MY
authors.lastname: Joo
authors.forename: Myung Geun
authors.initials: MG
authors.lastname: Shin
authors.forename: Soon Pal
authors.initials: SP
authors.lastname: Suh
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Ryang
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D001769:Blood / Q000382:microbiology; D002175:Candida / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D002177:Candidiasis / Q000382:microbiology*; D016000:Cluster Analysis; D003470:Culture Media / Q000737:chemistry; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D058889:Molecular Typing; D016533:Mycological Typing Techniques; D056910:Republic of Korea
chemical_list: D003470:Culture Media