title: Allele distribution of six STR/miniSTR loci (CD4, FABP2, D12S391, D14S1434, D22S1045 and D10S1248) for forensic purposes in Southeastern Brazil.
abstract: BACKGROUND
  Allele frequencies for six STR/miniSTR loci were determined in a sample of unrelated individuals from Southeastern Brazil.
  
  
  RESULTS
  No significant deviations from Hardy-Weinberg equilibrium proportions were observed for the loci investigated (p-values ≥ 0.2320). Statistical parameters of forensic interest such as heterozygosity (H), power of discrimination (PD) and power of exclusion (PE) were estimated. Except for marker FABP2, all STR/miniSTRs tested showed observed heterozygosities over 0.66.Combined power of discrimination and power of exclusion were 0.9999993 and 0.9925, respectively.
  
  
  CONCLUSIONS
  Due to their ease of analysis and high informativity, these new STR multiplexes will be useful for extending current marker sets for forensic and paternity purposes.
authors.affiliation: Departamento de Biologia Geral, Av. Antônio Carlos, Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Pampulha, Belo Horizonte, MG, Brazil.
authors.forename: Luciana Lara
authors.initials: LL
authors.lastname: dos Santos
authors.forename: Joana Bernardes
authors.initials: JB
authors.lastname: de Assis
authors.forename: Adriana Helena de Oliveira
authors.initials: AH
authors.lastname: Reis
authors.forename: Marília de Oliveira
authors.initials: Mde O
authors.lastname: Scliar
authors.forename: Maria Raquel Santos
authors.initials: MR
authors.lastname: Carvalho
authors.forename: Marco Túlio
authors.initials: MT
authors.lastname: Vaintraub
authors.forename: Patrícia
authors.initials: P
authors.lastname: Vaintraub
mesh_terms: D000483:Alleles; D001483:Base Sequence; D001938:Brazil; D015704:CD4 Antigens / Q000235:genetics*; D016172:DNA Fingerprinting; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D053803:Forensic Genetics; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D018895:Microsatellite Repeats; D010334:Paternity; D016133:Polymerase Chain Reaction
chemical_list: D015704:CD4 Antigens; C493404:FABP2 protein, human; D050556:Fatty Acid-Binding Proteins; D005819:Genetic Markers