title: Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse.
abstract: OBJECTIVE
  The aim of this study is to estimate efficacy and safety of mesh in surgery for uterine or vault prolapse.
  
  
  METHODS
  Seventeen electronic databases were searched for relevant studies that were published from 1980 onwards.
  
  
  RESULTS
  Fifty-four studies involving 7,054 women were included. For sacrocolpopexy (average follow-up 23 months), the risk of clinical recurrence ranged from 0% to 6%, persistent symptoms ranged from 3% to 31% and mesh erosion from 0% to 12%. For infracoccygeal sacropexy (average follow-up 13 months), the risk of clinical recurrence ranged from 0% to 25%, persistent symptoms from 2% to 21% and mesh erosion 0% to 21%. Limited evidence was available for sacrocolpoperineopexy and uterine suspension sling to draw reliable estimates.
  
  
  CONCLUSIONS
  Sacrocolpopexy was associated with a low risk of recurrence but with a relatively high risk of mesh erosion. Ranges of estimates for outcomes for other mesh techniques were wide.
authors.affiliation: Health Services Research Unit, University of Aberdeen, Aberdeen AB25 2ZD, UK. x.jia@abdn.ac.uk
authors.forename: Xueli
authors.initials: X
authors.lastname: Jia
authors.forename: Cathryn
authors.initials: C
authors.lastname: Glazener
authors.forename: Graham
authors.initials: G
authors.lastname: Mowatt
authors.forename: David
authors.initials: D
authors.lastname: Jenkinson
authors.forename: Cynthia
authors.initials: C
authors.lastname: Fraser
authors.forename: Christine
authors.initials: C
authors.lastname: Bain
authors.forename: Jennifer
authors.initials: J
authors.lastname: Burr
mesh_terms: D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D012449:Safety; D013526:Surgical Mesh / Q000009:adverse effects; D014596:Uterine Prolapse / Q000601:surgery*