An outbreak of severe leptospirosis in capuchin (Cebus) monkeys.
Naturally acquired acute leptospirosis in monkeys is uncommon. This study reports an outbreak of severe leptospirosis among 52 capuchin (Cebus) monkeys that had been rescued from homes and housed in a wildlife rehabilitation center in Colombia in 2007. Case confirmation consisted of Leptospira isolation followed by a polymerase chain reaction targeting the LipL32 gene. The attack and mortality rates were 71% and 27%, respectively. Sixteen cases were confirmed. Necropsy revealed diffuse jaundice and pulmonary hemorrhage. Multi-locus sequence typing identified the agent to be Leptospira interrogans sequence type 17, indicating rats as the source of infection. An environmental survey confirmed rodent infestation as the cause of the outbreak. The extent of Leptospira transmission between humans and monkeys is unknown. Improper husbandry of non-human primates could create new reservoirs and transmission routes for Leptospira threatening conservation efforts and public health.
Szonyi
Barbara
B
Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, NY 14853, USA. bs77@cornell.edu
Agudelo-Flórez
Piedad
P
Ramírez
Marcela
M
Moreno
Natali
N
Ko
Albert I
AI
D000818:Animals; D002428:Cebus / Q000382:microbiology; D004196:Disease Outbreaks / Q000662:veterinary; D004197:Disease Reservoirs / Q000382:microbiology / Q000662:veterinary*; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D005260:Female; D006801:Humans; D007922:Leptospirosis / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D008297:Male; D008992:Monkey Diseases / Q000453:epidemiology* / Q000635:transmission; D011634:Public Health; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology / Q000635:transmission