title: Right lobe estimated blood-free weight for living donor liver transplantation: accuracy of automated blood-free CT volumetry--preliminary results.
abstract: OBJECTIVE
  To determine the relative accuracy of automated blood-free to blood-filled computed tomographic (CT) volumetry for estimation of right-lobe weight in living donor liver transplantation.
  
  
  METHODS
  This retrospective study was approved by the institutional review board; informed consent was waived. Between October 1, 2008, and April 30, 2009, 88 live liver donors (54 men, 34 women; mean age, 26.1 years +/- 6.9 [standard deviation]) who underwent CT and had their right lobes procured in the study institution were included. Automated measurement of blood-filled volume (V(BFill)) and blood-free volume (V(BFree)) of the right lobe was performed by using 16-row multidetector CT performed with 5-mm intervals. Actual hepatic weight was measured blood free during surgery. Percentage blood volume, %V(B), was calculated as follows: %V(B) = V(BFill) - V(BFree)/V(BFill) . 100. Pearson tests were performed to determine correlation coefficients between V(BFill)/1.22 or V(BFree) and weight. Percentage deviation and percentage absolute deviation of V(BFree) from weight were compared with those of V(BFill)/1.22 by using a paired t test or Wilcoxon rank sum test. Regression analysis was performed between V(BFree) and weight.
  
  
  RESULTS
  Mean V(BFill), V(BFree), and weight were 789.0 mL +/- 126.4, 713.9 mL +/- 114.4, and 717.8 g +/- 110.4. Percentage blood volume varied from 6.5% to 19.8% (mean, 9.5%). Compared with weight, the correlation coefficient was slightly higher with V(BFree) (r = 0.9140) than with V(BFill)/1.22 (r = 0.8909). Mean percentage deviation and percentage absolute deviation were significantly smaller with V(BFree) (-0.4% +/- 6.3, 5.0% +/- 3.8; P < .001) than with V(BFill)/1.22 (-9.8% +/- 6.5, 10.2% +/- 7.3; P < .001). The equation relating V(BFree) and weight, W, was as follows: W = (0.8815 . V(BFree)) + 88.5117, with R(2) of 0.8355 (P < .001).
  
  
  CONCLUSIONS
  At automated CT volumetry in live liver donors, the percentage blood volume varies. The V(BFree) is more accurate than is V(BFill)/1.22 in estimation of hepatic weight.
authors.affiliation: Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap 2-dong, Songpa-ku, Seoul 138-736, Korea. kimkw@amc.seoul.kr
authors.forename: Kyoung Won
authors.initials: KW
authors.lastname: Kim
authors.forename: Jeongjin
authors.initials: J
authors.lastname: Lee
authors.forename: Ho
authors.initials: H
authors.lastname: Lee
authors.forename: Woo Kyoung
authors.initials: WK
authors.lastname: Jeong
authors.forename: Hyung Jin
authors.initials: HJ
authors.lastname: Won
authors.forename: Yong Moon
authors.initials: YM
authors.lastname: Shin
authors.forename: Dong-Hwan
authors.initials: DH
authors.lastname: Jung
authors.forename: Jeong Ik
authors.initials: JI
authors.lastname: Park
authors.forename: Gi-Won
authors.initials: GW
authors.lastname: Song
authors.forename: Tae-Yong
authors.initials: TY
authors.lastname: Ha
authors.forename: Deok-Bog
authors.initials: DB
authors.lastname: Moon
authors.forename: Ki-Hun
authors.initials: KH
authors.lastname: Kim
authors.forename: Chul-Soo
authors.initials: CS
authors.lastname: Ahn
authors.forename: Shin
authors.initials: S
authors.lastname: Hwang
authors.forename: Sung-Gyu
authors.initials: SG
authors.lastname: Lee
mesh_terms: D000328:Adult; D001810:Blood Volume; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D016031:Liver Transplantation / Q000000981:diagnostic imaging*; D019520:Living Donors; D008297:Male; D009929:Organ Size; D010865:Pilot Projects; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*