title: Effects of selenium diets on growth, accumulation and antioxidant response in juvenile carp.
abstract: An 8-week feeding trial was undertaken with Cyprinus carpio to determine the effects of two commercial Se diets (HSe 1.0 mg kg⁻¹ and LSe 0.25 mg kg⁻¹) on growth, accumulation and antioxidant response in juveniles at time 0, 30 and 60 days. HSe carp had higher mean weight (W) values than LSe group at 60 days and the Fulton condition factor (K) indicated good fish health for both diet groups. Among the investigated HSe tissues, kidney and liver were mainly involved in Se accumulation, whereas the Se level in muscle indicated a very low Se contamination risk for human health. Selenium accumulation levels in HSe tissues followed this order: kidney>liver>muscle. Although growth was not impaired, biochemical antioxidant indicators in liver and kidney evidenced an oxidative stress condition in HSe juveniles. Furthermore, selenium supplementation levels, higher than the one employed in this study, might worsen the antioxidant status of carp.
authors.affiliation: Ecotoxicology Laboratory, Department of Cellular and Environmental Biology, University of Perugia, Perugia, Italy.
authors.forename: Antonia Concetta
authors.initials: AC
authors.lastname: Elia
authors.forename: Marino
authors.initials: M
authors.lastname: Prearo
authors.forename: Nicole
authors.initials: N
authors.lastname: Pacini
authors.forename: Ambrosius Josef Martin
authors.initials: AJ
authors.lastname: Dörr
authors.forename: Maria Cesarina
authors.initials: MC
authors.lastname: Abete
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001835:Body Weight; D002347:Carps / Q000254:growth & development* / Q000378:metabolism*; D019587:Dietary Supplements; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D018482:Muscle, Skeletal / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects; D012643:Selenium / Q000493:pharmacokinetics* / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000975:Antioxidants; D012643:Selenium