Allele distribution of six STR/miniSTR loci (CD4, FABP2, D12S391, D14S1434, D22S1045 and D10S1248) for forensic purposes in Southeastern Brazil.
BACKGROUND
Allele frequencies for six STR/miniSTR loci were determined in a sample of unrelated individuals from Southeastern Brazil.


RESULTS
No significant deviations from Hardy-Weinberg equilibrium proportions were observed for the loci investigated (p-values ≥ 0.2320). Statistical parameters of forensic interest such as heterozygosity (H), power of discrimination (PD) and power of exclusion (PE) were estimated. Except for marker FABP2, all STR/miniSTRs tested showed observed heterozygosities over 0.66.Combined power of discrimination and power of exclusion were 0.9999993 and 0.9925, respectively.


CONCLUSIONS
Due to their ease of analysis and high informativity, these new STR multiplexes will be useful for extending current marker sets for forensic and paternity purposes.
dos Santos
Luciana Lara
LL
Departamento de Biologia Geral, Av. Antônio Carlos, Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Pampulha, Belo Horizonte, MG, Brazil.
de Assis
Joana Bernardes
JB
Reis
Adriana Helena de Oliveira
AH
Scliar
Marília de Oliveira
Mde O
Carvalho
Maria Raquel Santos
MR
Vaintraub
Marco Túlio
MT
Vaintraub
Patrícia
P
D000483:Alleles; D001483:Base Sequence; D001938:Brazil; D015704:CD4 Antigens / Q000235:genetics*; D016172:DNA Fingerprinting; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D053803:Forensic Genetics; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D018895:Microsatellite Repeats; D010334:Paternity; D016133:Polymerase Chain Reaction
D015704:CD4 Antigens; C493404:FABP2 protein, human; D050556:Fatty Acid-Binding Proteins; D005819:Genetic Markers