Functional characterisation of the extrastriate body area based on the N1 ERP component.
Electrophysiological and functional neuroimaging evidence points to the existence of neural populations that respond strongly and selectively to the appearance of the human body and its parts. However, the relationship between ERP and fMRI markers of these populations remains unclear. Here we used a previously identified functional dissociation between two body-selective regions identified with fMRI (extrastriate body area or EBA; fusiform body area or FBA) in order to better understand the source of a body-selective N1 ERP component. Specifically, we compared the magnitude of the N1 elicited by images of fingers, hands, arms and bodies to that obtained for hierarchically-matched control stimuli. We found close agreement between the pattern of body-part selectivity exhibited by N1, and the pattern of BOLD selectivity elicited in a previous study by the same type of stimuli in EBA (in contrast to FBA). We interpret these findings as evidence for EBA as the primary generator of the body-selective N1 component. Our results are an example of the use of functional criteria to distinguish among the possible neural sources of ERP markers.
Taylor
John C
JC
Wales Institute of Cognitive Neuroscience, Bangor University, United Kingdom. psp223@bangor.ac.uk
Roberts
Mark V
MV
Downing
Paul E
PE
Thierry
Guillaume
G
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D009778:Occipital Lobe / Q000033:anatomy & histology* / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000502:physiology; D012016:Reference Values; D013702:Temporal Lobe / Q000033:anatomy & histology* / Q000502:physiology; D014796:Visual Perception / Q000502:physiology; D055815:Young Adult