A Case of p-ANCA-Positive Propylthiouracil-Induced Pyoderma Gangrenosum.
Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who presented with cutaneous manifestations of pyoderma gangrenosum with simultaneous development of p-ANCAs during PTU therapy for Graves' disease.
Seo
Jong Won
JW
Department of Dermatology, Maryknoll Medical Center, Busan, Korea.
Son
Hyun Ho
HH
Choi
Joon Hee
JH
Lee
Sook Kyung
SK