title: Relationship between prostate-specific antigen and body mass index according to age: lower prostate-specific antigen in middle-aged overweight and obese Korean men.
abstract: OBJECTIVE
  To analyze the relationship between serum prostate-specific antigen (PSA) and body mass index (BMI) according to age in a population of ostensibly healthy Korean men.
  
  
  METHODS
  Between 2002 and 2006, data from 13,025 men who visited health promotion centers were evaluated. All men underwent anthropometric measurements and serum PSA determination. The relationship between serum PSA and BMI according to age was analyzed.
  
  
  RESULTS
  The median age was 50.0 years and the median serum PSA level was 0.69 ng/ml. There was no relationship between serum PSA and BMI in the group whose BMI was <23 kg/m(2). The serum PSA showed a significant inverse relationship in those with BMI of ≥23 kg/m(2). However, this finding was only true among 40- to 59-year-old middle aged men and no such relationship between serum PSA and BMI was seen in the older groups (60-79 years of age).
  
  
  CONCLUSIONS
  Our study revealed serum PSA had a significant inverse relationship with BMI in overweight and obese men aged between 40 and 59 years; however, there was no relationship between serum PSA and BMI in men whose age was older than 60 years.
authors.affiliation: Department of Urology, College of Medicine, Soonchunhyang University, Seoul, Korea.
authors.forename: Won Jae
authors.initials: WJ
authors.lastname: Yang
authors.forename: Sang Hyeon
authors.initials: SH
authors.lastname: Cheon
authors.forename: Young Sig
authors.initials: YS
authors.lastname: Kim
authors.forename: Dong Jun
authors.initials: DJ
authors.lastname: Kim
authors.forename: Do Hwan
authors.initials: do H
authors.lastname: Seong
authors.forename: Yun Seob
authors.initials: YS
authors.lastname: Song
authors.forename: Soung Yong
authors.initials: SY
authors.lastname: Cho
authors.forename: In Rae
authors.initials: IR
authors.lastname: Cho
authors.forename: Sun Il
authors.initials: SI
authors.lastname: Kim
authors.forename: Se Joong
authors.initials: SJ
authors.lastname: Kim
authors.forename: Chun Il
authors.initials: CI
authors.lastname: Kim
authors.forename: Young Deuk
authors.initials: YD
authors.lastname: Choi
authors.forename: Sung Joon
authors.initials: SJ
authors.lastname: Hong
authors.forename: Hyoungjune
authors.initials: H
authors.lastname: Im
authors.forename: Jin Seon
authors.initials: JS
authors.lastname: Cho
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D044466:Asian People; D015992:Body Mass Index; D015536:Down-Regulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000208:ethnology*; D050177:Overweight / Q000097:blood* / Q000208:ethnology*; D017430:Prostate-Specific Antigen / Q000097:blood*; D056910:Republic of Korea
chemical_list: D017430:Prostate-Specific Antigen