ACE I/D genotype, habitual physical activity, and blood pressure in children.
The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p < .05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.
Sarzynski
Mark A
MA
Depts. of Kinesiology and Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA.
Eisenmann
Joey C
JC
Welk
Gregory J
GJ
Tucker
Jared
J
Glenn
Kim
K
Rothschild
Max
M
Heelan
Kate
K
D001794:Blood Pressure; D050218:Body Fat Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D015438:Health Behavior; D006801:Humans; D054643:INDEL Mutation; D008297:Male; D009043:Motor Activity; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide
D007703:Peptidyl-Dipeptidase A