title: Ligational, analytical and biological applications on oxalyl bis(3,4-dihydroxybenzylidene) hydrazone.
abstract: The molecular modeling and parameters have been calculated to confirm the geometry of oxalyl bis(3,4-dihydroxybenzylidene) hydrazone, H(6)L. The metal complexes of Cr(3+), VO(2+), ZrO(2+), HfO(2+), UO(2)(2+) and MoO(2)(2+) with H(6)L have been prepared and characterized by partial elemental analysis, spectral studies (electronic; IR), thermal analysis and magnetic measurements. The data suggest the formation of polymer complexes with a unit [Cr(H(4)L)(H(2)O)(3)Cl].H(2)O, [VO(H(4)L)(H(2)O)(2)], [Hf(H(4)L)(H(2)O)].H(2)O [UO(2)(H(4)L)(H(2)O)(2)].2H(2)O [MoO(2)(H(4)L)] and [(ZrO)(2)(H(2)L)-(C(2)H(5)OH)(2)]. The ligand behaves as a dibasic bidentate in all complexes except ZrO(2+) which acts as a tetrabasic tetradentate with the two ZrO(2+) ions. An octahedral geometry was proposed for the Cr(3+), HfO(2+), MoO(2)(2+)and UO(2)(2+) complexes and square pyramid for VO(2+). The Cr(3+) is necessary to degrade the DNA of eukaryotic subject completely; the other complexes have little effect. H(6)L was found suitable as a new reagent for the separation and preconcentration of ZrO(2+) ions from different water samples using flotation technique with satisfactory results.
authors.affiliation: Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Dakhalia 35516, Egypt. aelasmy@yahoo.com
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: El-Asmy
authors.forename: O A
authors.initials: OA
authors.lastname: El-Gammal
authors.forename: H A
authors.initials: HA
authors.lastname: Radwan
authors.forename: S E
authors.initials: SE
authors.lastname: Ghazy
mesh_terms: D000818:Animals; D001593:Benzyl Compounds / Q000737:chemistry* / Q000494:pharmacology*; D002417:Cattle; D003116:Color; D004247:DNA / Q000187:drug effects; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D006835:Hydrazones / Q000737:chemistry* / Q000494:pharmacology*; D007477:Ions; D008280:Magnetics; D008958:Models, Molecular; D013055:Spectrophotometry, Infrared; D013696:Temperature; D013818:Thermogravimetry; D015040:Zirconium / Q000737:chemistry
chemical_list: D001593:Benzyl Compounds; D006835:Hydrazones; D007477:Ions; C552648:oxalyl bis(3,4-dihydroxybenzylidene) hydrazone; D004247:DNA; C427203:calf thymus DNA; D015040:Zirconium; C028541:zirconium oxide