title: Relationship between uric acid and metabolic syndrome according to menopausal status.
abstract: OBJECTIVE
  Uric acid, the levels of which have been shown to increase after menopause, has been associated with metabolic syndrome. The prevalence of metabolic syndrome has also been determined to increase after menopause. Therefore, we surmised that menopausal status-specific analyses for the characterisation of the relationship between uric acid and the metabolic syndrome were warranted.
  
  
  METHODS
  We included 1644 patients: 1018 premenopausal women and 626 postmenopausal women, all of whom participated in annual health examinations at Anam Hospital in Seoul, Korea, from January 2008 through December 2008.
  
  
  RESULTS
  On the multivariate logistic regression analysis, uric acid was identified as an independent risk factor for metabolic syndrome in both premenopausal and postmenopausal women. Uric acid levels had different relationships with blood pressure based on menopausal status, however, no such relationships with fasting glucose or age were found.
  
  
  CONCLUSIONS
  Increased uric acid levels were associated with increased risk for metabolic syndrome in both premenopausal and postmenopausal women. In studies regarding uric acid and metabolic syndrome in women, the effects of menopausal status should be considered.
authors.affiliation: Department of Obstetrics and Gynecology, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea.
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Lee
authors.forename: Hyun Tae
authors.initials: HT
authors.lastname: Park
authors.forename: Geum Joon
authors.initials: GJ
authors.lastname: Cho
authors.forename: Kyung Wook
authors.initials: KW
authors.lastname: Yi
authors.forename: Ki Hoon
authors.initials: KH
authors.lastname: Ahn
authors.forename: Jung-Ho
authors.initials: JH
authors.lastname: Shin
authors.forename: Tak
authors.initials: T
authors.lastname: Kim
authors.forename: Young Tae
authors.initials: YT
authors.lastname: Kim
authors.forename: Jun Young
authors.initials: JY
authors.lastname: Hur
authors.forename: Sun Haeng
authors.initials: SH
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D033461:Hyperuricemia / Q000453:epidemiology; D007333:Insulin Resistance / Q000502:physiology; D008055:Lipids / Q000097:blood; D008593:Menopause / Q000097:blood* / Q000502:physiology; D024821:Metabolic Syndrome / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood*
chemical_list: D008055:Lipids; D014527:Uric Acid