title: Fulminant pancytopenia due to cytomegalovirus infection in an immunocompetent adult.
abstract: A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.
authors.affiliation: 15th Department of Medicine, Division of Infectious Diseases, Evangelismos General Hospital, 45-47 Ipsilantou street, Athens, Greece. mkoukoulaki@gmail.com
authors.forename: Maria
authors.initials: M
authors.lastname: Koukoulaki
authors.forename: Georgia
authors.initials: G
authors.lastname: Ifanti
authors.forename: Eirini
authors.initials: E
authors.lastname: Grispou
authors.forename: Vassilios
authors.initials: V
authors.lastname: Papastamopoulos
authors.forename: Georgia
authors.initials: G
authors.lastname: Chroni
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Diamantopoulos
authors.forename: Athanasios
authors.initials: A
authors.lastname: Skoutelis
mesh_terms: D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D018805:Sepsis / Q000209:etiology*; D012720:Severity of Illness Index
chemical_list: D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D011239:Prednisolone