title: [Peptic ulcer: facts and questions -- 2010].
abstract: Etiology and clinical manifestation of the peptic ulcer keep changes nowadays. Helicobacter pylori-infection, nonsteroidal anti-inflammatory drugs and small dosage acetic acid treatment are the main etiological factors. Helicobacter pylori positive peptic ulcer can be treated with eradication of the bacterium. Prevention of the NSAID-ulcer and the prescription of the acid suppressive therapy depend on the gastrointestinal and cardiovascular risk factors of patient. Despite of the effective therapies, there are still questions to answer. The number of Helicobacter pylori and NSAID negative ulcers is likely to increase, their therapy must be clarified. There's a fall in the eradication rate of Helicobacter pylori infection, the optimal treatment is missing.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar II. Belgyógyászati Klinika, Budapest. hagymasikriszti@freemail.hu
authors.forename: Krisztina
authors.initials: K
authors.lastname: Hagymási
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Tulassay
mesh_terms: D000863:Antacids / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D015994:Incidence; D010437:Peptic Ulcer / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000517:prevention & control* / Q000523:psychology; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications
chemical_list: D000863:Antacids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D054328:Proton Pump Inhibitors