Intermolecular C-O addition of carboxylic acids to arynes.
A novel, efficient, and expedient route to biologically and pharmaceutically important o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed starting from readily available carboxylic acids and commercially available o-(trimethylsilyl)aryl triflates.
Dubrovskiy
Anton V
AV
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Larock
Richard C
RC
D001554:Benzene / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
D002264:Carboxylic Acids; D002244:Carbon; D001554:Benzene; D010100:Oxygen