Metal-free reductions of N-heterocycles via Lewis acid catalyzed hydrogenation.
N-Heterocycles form weak adducts with B(C(6)F(5))(3) that exist in equilibrium with the corresponding FLP; nonetheless, these heterocycles are reduced in the presence of a catalytic amount of the borane B(C(6)F(5))(3) and H(2).
Geier
Stephen J
SJ
Department of Chemistry, 80 St. George St., University of Toronto, Toronto, Ontario, CanadaM5S 3H6.
Chase
Preston A
PA
Stephan
Douglas W
DW