Urinary type IV collagen excretion predicts subsequent declining renal function in type 2 diabetic patients with proteinuria.
Baseline urinary type IV collagen excretion was negatively correlated with the subsequent GFR change (r(s)=-0.39, p=0.04) in our cohort of 30 type 2 diabetic patients with proteinuria. Therefore, it could be used to predict subsequent declining renal function in type 2 diabetic patients with proteinuria.
Katavetin
Pisut
P
Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, 1873 Rama IV Road, Pathumwan, Bangkok 10330, Thailand. pkatavetin@yahoo.com
Katavetin
Paravee
P
Susantitaphong
Paweena
P
Townamchai
Natavudh
N
Tiranathanagul
Khajohn
K
Tungsanga
Kriang
K
Eiam-Ong
Somchai
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D024141:Collagen Type IV / Q000652:urine*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000503:physiopathology* / Q000652:urine*; D003928:Diabetic Nephropathies / Q000473:pathology* / Q000652:urine*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000188:drug therapy / Q000473:pathology* / Q000652:urine*
D000806:Angiotensin-Converting Enzyme Inhibitors; D024141:Collagen Type IV