title: Genes predict village of origin in rural Europe.
abstract: The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30  km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
authors.affiliation: Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.
authors.forename: Colm
authors.initials: C
authors.lastname: O'Dushlaine
authors.forename: Ruth
authors.initials: R
authors.lastname: McQuillan
authors.forename: Michael E
authors.initials: ME
authors.lastname: Weale
authors.forename: Daniel J M
authors.initials: DJ
authors.lastname: Crouch
authors.forename: Asa
authors.initials: A
authors.lastname: Johansson
authors.forename: Yurii
authors.initials: Y
authors.lastname: Aulchenko
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Franklin
authors.forename: Ozren
authors.initials: O
authors.lastname: Polašek
authors.forename: Christian
authors.initials: C
authors.lastname: Fuchsberger
authors.forename: Aiden
authors.initials: A
authors.lastname: Corvin
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Hicks
authors.forename: Veronique
authors.initials: V
authors.lastname: Vitart
authors.forename: Caroline
authors.initials: C
authors.lastname: Hayward
authors.forename: Sarah H
authors.initials: SH
authors.lastname: Wild
authors.forename: Thomas
authors.initials: T
authors.lastname: Meitinger
authors.forename: Cornelia M
authors.initials: CM
authors.lastname: van Duijn
authors.forename: Ulf
authors.initials: U
authors.lastname: Gyllensten
authors.forename: Alan F
authors.initials: AF
authors.lastname: Wright
authors.forename: Harry
authors.initials: H
authors.lastname: Campbell
authors.forename: Peter P
authors.initials: PP
authors.lastname: Pramstaller
authors.forename: Igor
authors.initials: I
authors.lastname: Rudan
authors.forename: James F
authors.initials: JF
authors.lastname: Wilson
mesh_terms: D005060:Europe; D005192:Family Health; D005828:Genetics, Population / Q000379:methods*; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D008957:Models, Genetic; D020641:Polymorphism, Single Nucleotide; D025341:Principal Component Analysis; D012424:Rural Population