A rare case of segmental neurofibromatosis involving the sciatic nerve.
Segmental neurofibromatosis (NF-5) is an extremely rare variant of neurofibromatosis involving a single extremity without pathologic features beyond the midline. A case of segmental neurofibromatosis involving the sciatic nerve and its branches is presented with a detailed description of the patient's preoperative findings plus postoperative course through 1-year follow-up. Clinical, histologic, and genetic findings are given along with a brief review of the literature on segmental neurofibromatosis. Last, treatment options and postoperative care recommendations are provided.
Trocchia
Aron
A
Department of Orthopaedics, William Beaumont Hospital, Royal Oak, Michigan 48073, USA. aron@drexel.edu
Reyes
Alma
A
Wilson
Jon
J
Les
Kimberly
K
D000328:Adult; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D017253:Neurofibromatoses / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009418:S100 Proteins / Q000378:metabolism; D012583:Schwann Cells / Q000378:metabolism; D012584:Sciatic Nerve / Q000473:pathology* / Q000601:surgery
D009418:S100 Proteins