Histological differences between the mucosa on the medial and lateral sides of the normal uncinate process.
OBJECTIVE
To determine whether histological differences exist between the medial and lateral sides of the normal mucosa of the uncinate process (UP).


METHODS
Retrospective histological analysis.


METHODS
Twenty UPs from the nasal cavities of 17 patients with no evidence of sinus disease were harvested during endoscopic sinus surgery. The dissected mucosa was stained with hematoxylin and eosin, chromotrope 2R, alcian blue-periodic acid-Schiff, and toluidine blue.


RESULTS
: The thickness of the nasal mucosa was significantly greater on the medial side of the UPs than on the lateral side (173 +/- 72 microm vs. 157 +/- 14 microm). The thickness of the basement membrane of the lamina propria of the mucosa was significantly greater on the medial side of the UPs than on the lateral side (2.8 +/- 2.5 microm vs. 0.8 +/- 1.0 microm). The thickness of the epithelium was greater on the lateral side than on the medial side (14 +/- 3 microm vs. 12 +/- 3 microm). The area of mucous glands was larger on the medial side than on the lateral side (43 +/- 13 x 10(-2) mm(2) vs. 33 +/- 12 x 10(-2) mm(2)). Meanwhile, the number of mast cells (4.0 +/- 1.2 vs. 1.8 +/- 0.2) and goblet cells (23.1 +/- 12.3 vs. 10.5 +/- 10.2) were both found to be higher on the lateral side than on the medial side.


CONCLUSIONS
There are histological differences between the mucosa on the medial and lateral sides of the normal UP.
She
Wenyu
W
Key Laboratory of Otolaryngology, Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing, China.
Wang
Xiaoyan
X
Han
Demin
D
Zhang
Luo
L
D000293:Adolescent; D000328:Adult; D001485:Basement Membrane / Q000166:cytology; D004847:Epithelial Cells / Q000166:cytology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000166:cytology*; D012189:Retrospective Studies