Microbial glucosylation of flavonols by Cunninghamella echinulata.
We report here that flavonol (3-hydroxyflavone) was O-glucosylated efficiently by filamentous fungus Cunninghamella echinulata. Kaemferol and some other flavonols were also glucosylated. The novel conversion is expected to be applicable to prepare glycosylated flavonoids which are commonly found in plants and mammalian metabolites of related compounds.
Miyakoshi
Shunichi
S
Gunma National College of Technology, 580 Toriba-machi, Maebashi, Gunma, 371-8530, Japan. miyako@nat.gunma-ct.ac.jp
Azami
Shun
S
Kuzuyama
Tomohisa
T
D050260:Carbohydrate Metabolism / Q000502:physiology*; D020093:Cunninghamella; D044948:Flavonols / Q000096:biosynthesis*; D018942:Macrolides / Q000378:metabolism
D044948:Flavonols; D018942:Macrolides; C027837:moxidectin