title: [Epstein-Barr virus associated pulmonary lymphoma in Sjögren's syndrome].
abstract: A 71 year-old man with primary Sjögren's syndrome developed pulmonary opacities within two years of the diagnosis. Videothoracoscopic lung biopsy demonstrated high grade, B-cell, CD20+, large-cell lymphoma, associated with Epstein-Barr virus (RNA EBERs of the virus were expressed by the lymphoma cells). The condition initially improved with rituximab-CHOP treatment, but recurrence of the lymphoma was fatal.
  
  
  CONCLUSIONS
  High-grade B-cell lymphoma associated with EBV can occur in Sjögren's syndrome in the absence of long-term immunosuppressive therapy.
authors.affiliation: UMR 754, service de pneumologie, centre de référence des maladies pulmonaires rares, hôpital Louis-Pradel, université de Lyon, 69677 Lyon (Bron) cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Traclet
authors.forename: V
authors.initials: V
authors.lastname: Cottin
authors.forename: B
authors.initials: B
authors.lastname: Duvert
authors.forename: F
authors.initials: F
authors.lastname: Thivolet-Bejui
authors.forename: F
authors.initials: F
authors.lastname: Berger
authors.forename: B
authors.initials: B
authors.lastname: Coiffier
authors.forename: J-F
authors.initials: JF
authors.lastname: Cordier
mesh_terms: D000368:Aged; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000821:virology*; D016393:Lymphoma, B-Cell / Q000821:virology*; D008297:Male; D012859:Sjogren's Syndrome / Q000150:complications*