title: [Neostigmine test for the diagnosis of congenital hypertrofic pyloric stenosis during the last 50 years].
abstract: Since a half of XXI Century had been used the neostigmine test for the diagnosis of congenital hypertrofic pyloris stenosis with satisfactory results in newborns. The neostigmine test consist in the intramuscular application of 0.5 mL of neostigmine metilsulfate in a dilution of 1:2000. The reproduction of the characteristic clinic picture (gastric wave passing from left to right, a pyloric olive can be felt through the abdominal wall and possible vomiting) 20 minutes after is considered a positive test. The test is quite simple, economic, easy to observe and its results are confidence after 50 years.
authors.forename: Andrés E
authors.initials: AE
authors.lastname: Straffon-Osorno
mesh_terms: D049673:History, 20th Century; D006801:Humans; D009388:Neostigmine / Q000266:history; D046248:Pyloric Stenosis, Hypertrophic / Q000175:diagnosis*
chemical_list: D009388:Neostigmine