Concomitant pulmonary infection with Nocardia transvalensis and Aspergillus ustus in lung transplantation.
Lung infections with Nocardia and Aspergillus spp in lung transplant recipients (LTRs) create diagnostic and therapeutic challenges. The present case illustrates the difficulties in identifying these pathogens in LTRs. A high degree of clinical suspicion and aggressive early management are required to ensure good outcomes. Although prospective data on treating these conditions are scarce, the empiric use of combination broad-spectrum anti-microbials initially seems prudent.
Cabada
Miguel M
MM
Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-0772, USA.
Nishi
Shawn P
SP
Lea
Alfred S
AS
Schnadig
Vicki
V
Lombard
Gisele A
GA
Lick
Scott D
SD
Valentine
Vincent G
VG
D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001230:Aspergillus; D015897:Comorbidity; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000276:immunology / Q000601:surgery*; D007165:Immunosuppression Therapy; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016040:Lung Transplantation / Q000276:immunology; D008297:Male; D009615:Nocardia; D009617:Nocardia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D055732:Pulmonary Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome
D000890:Anti-Infective Agents