title: Women and bleeding disorders.
abstract: While women are rarely affected by haemophilia, they are equally as likely as men to have other bleeding disorders. Menorrhagia, or heavy menstrual bleeding, is the most common symptom that they experience. Not only is menorrhagia more prevalent among women with bleeding disorders, but bleeding disorders are more prevalent among women with menorrhagia. Although menorrhagia is the most common reproductive tract manifestation of a bleeding disorder, it is not the only manifestation. Women with bleeding disorders appear to be at an increased risk of developing haemorrhagic ovarian cysts and possibly endometriosis. Women suspected of having a bleeding disorder or being a carrier of haemophilia should be offered diagnostic testing before getting pregnant to allow for appropriate preconception counselling and pregnancy management. During pregnancy, women with bleeding disorders may be at an increased risk of bleeding complications. At the time of childbirth, women with bleeding disorders appear to be more likely to experience postpartum haemorrhage, particularly delayed or secondary postpartum haemorrhage. As women with bleeding disorders grow older, they may be more likely to manifest gynaecological conditions which present with bleeding. Women with bleeding disorders are more likely to undergo a hysterectomy and are more likely to have the operation at a younger age. While women with bleeding disorders are at risk for the same obstetrical and gynaecological problems that affect all women, women with bleeding disorders are disproportionately affected by conditions that manifest with bleeding. Optimal management involves the combined expertise of haemostasis experts and obstetrician-gynaecologists.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA. andra.james@duke.edu
authors.forename: A H
authors.initials: AH
authors.lastname: James
mesh_terms: D000293:Adolescent; D000328:Adult; D003270:Contraceptive Agents / Q000627:therapeutic use; D005260:Female; D006176:Gynecology / Q000379:methods; D006474:Hemorrhagic Disorders / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D008595:Menorrhagia / Q000453:epidemiology / Q000628:therapy*; D009774:Obstetrics / Q000379:methods; D006473:Postpartum Hemorrhage / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D014842:von Willebrand Diseases / Q000453:epidemiology / Q000628:therapy
chemical_list: D003270:Contraceptive Agents