Distribution of HLA-B27 in Romanian spondyloarthritides patients.
The analysis of 310 Romanian spondyloarthritides patients confirmed the association of the HLA-B27 marker with the susceptibility to different diseases of this group. For ankylosing spondylitis, the HLA-B27 frequency in Romanian patients (72.1%) was similar to that found in several regions in the Mediterranean area.
Popa
O M
OM
Faculty of Medicine, Department of Immunology and Pathophysiology, University Carol Davila, Bucharest, Romania. oliviapopa@yahoo.com
Bojinca
M
M
Bojinca
V
V
Ciofu
C
C
Dutescu
M I
MI
Bardan
A
A
Sfrent-Cornateanu
R
R
Petrek
M
M
Bara
C
C
Popa
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000483:Alleles; D015535:Arthritis, Psoriatic / Q000235:genetics* / Q000276:immunology; D016918:Arthritis, Reactive / Q000235:genetics* / Q000276:immunology; D004198:Disease Susceptibility; D005260:Female; D005787:Gene Frequency; D005805:Genes, MHC Class I; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D015796:HLA-B27 Antigen / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012383:Romania; D025241:Spondylarthritis / Q000235:genetics* / Q000276:immunology; D013167:Spondylitis, Ankylosing / Q000235:genetics* / Q000276:immunology
D005819:Genetic Markers; D015796:HLA-B27 Antigen