title: [Pilot plant for microbiological synthesis. Engineer and technological aspects].
abstract: A biotechnological pilot plant (National Research Centre of Antibiotics) and its technical potentialities in production of various biosynthetic products are described. Some engineer and technological aspects of the fermentation equipment and particularly sterilization of the media and apparatus, fermentation broth aeration under sterile conditions and control of biosynthesis technological parameters (t degrees, pO2, P, pH, foaming, etc.) are considered. The pilot plant is designed for fermentation processes under aseptic conditions with the use practically of any object, from bacteria to tissue cultures.
authors.forename: A V
authors.initials: AV
authors.lastname: Lukanin
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D019149:Bioreactors; D004345:Drug Industry / Q000295:instrumentation* / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents