Fluorocyanation of enamines.
A method for the fluorocyanation of enamines has been described. The reaction involves fluorination of the electron rich double bond with N-F reagent (Selectfluor or NFSI) accompanied by trapping of beta-fluoroiminium cationic intermediate with cyanide nucleophile.
Dilman
Alexander D
AD
N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation. adil25@mail.ru
Belyakov
Pavel A
PA
Struchkova
Marina I
MI
Arkhipov
Dmitry E
DE
Korlyukov
Alexander A
AA
Tartakovsky
Vladimir A
VA
D000588:Amines / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
D000588:Amines; D003486:Cyanides; D005461:Fluorine