title: Pigmented pleomorphic xanthoastrocytoma: a rare variant and literature review.
abstract: A 16-year-old male teenager presented with seizure and loss of consciousness for 20 min. Magnetic resonance imaging demonstrated a mass occupying the right medial temporal lobe. Histological examination revealed a non-pigmented area with spindle-shaped and large xanthomatous pleomorphic cells and a pigmented region with pigmented neoplastic cells with fascicular arrangement. Immunohistochemical studies showed the tumor was positive for GFAP and low index of Ki-67. Considering the patient's history, clinical data and pathological findings, we rendered a rare variant named pigmented pleomorphic xanthoastrocytoma.
authors.affiliation: Department of Neuropathology, Institute of Neurology, Huashan Hospital of Fudan University, Shanghai, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Xiong
authors.forename: Shu-Guang
authors.initials: SG
authors.lastname: Chu
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
authors.forename: Yin
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D010858:Pigmentation
chemical_list: D014408:Biomarkers, Tumor