Improved blood pressure control in elderly hypertensive patients: results of the PAPY-65 Survey.
BACKGROUND
Blood pressure (BP) control is far from optimal. Studies on factors influencing BP control in the elderly are limited, yet identification of factors contributing to the low rate of BP control is a prerequisite to improvement of clinical management.


OBJECTIVE
To evaluate the rate of BP control and the relationship between different clinical characteristics and BP control in treated hypertensive outpatients aged >or=65 years.


METHODS
The PAPY-65 Survey was a prospective cross-sectional survey conducted in primary care in Belgium in 2007. Participating primary-care physicians were required to include consecutive hypertensive patients aged >or=65 years and treated with antihypertensive drugs. Demographic and anthropometric data as well as data on cardiovascular risk factors and history were obtained. BP was measured in accordance with the European Society of Hypertension/European Society of Cardiology guidelines.


RESULTS
The mean +/- standard deviation (SD) age of the 1272 patients enrolled in the survey was 75 +/- 7 years; 702 (55%) patients were women. The mean +/- SD systolic/diastolic BP was 134/79 +/- 13/8 mmHg. BP was normalized (reduced to <140/90 mmHg, or <130/80 mmHg in patients with diabetes mellitus) in 617 (48.5%) patients overall and in 88 (24%) patients with diabetes (n = 371). The majority of patients (921; 72%) were treated with two or more antihypertensive drugs. Both general obesity (body mass index >or=30 vs <25 kg/m2) and abdominal obesity were associated with lack of BP control (unadjusted odds ratio [OR] 2.988, 95% CI 2.200, 4.057 and OR 2.066, 95% CI 1.649, 2.588, respectively). Abdominal obesity was no longer related to BP control when adjusted for the presence of diabetes. Diabetes was strongly associated with lack of BP control only when a stringent definition of BP control (<130/80 mmHg) was used. The combined presence of subclinical organ damage and a history of cardiovascular disease was associated with less uncontrolled BP (OR 0.62, 95% CI 0.48, 0.80).


CONCLUSIONS
Compared with previous data in the elderly in Belgium, a clear improvement in BP control was observed, probably related to the use of more antihypertensive agents. The presence of diabetes, excess bodyweight and abdominal obesity were all associated with poor BP control.
Van der Niepen
Patricia
P
Department of Nephrology and Hypertension, Universitair Ziekenhuis Brussel, Brussels, Belgium. hemovnnp@uzbrussel.be
Dupont
Alain G
AG
D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001530:Belgium; D001794:Blood Pressure / Q000187:drug effects*; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000503:physiopathology; D004359:Drug Therapy, Combination; D005260:Female; D006306:Health Surveys; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009765:Obesity / Q000150:complications; D056128:Obesity, Abdominal / Q000150:complications; D011320:Primary Health Care; D011446:Prospective Studies
D000959:Antihypertensive Agents