Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility.
During trauma resuscitation involving massive transfusion, the best fresh-frozen plasma to packed red blood cells ratio is unknown. No randomised controlled trial (RCT) is available on this subject, although there are plenty of observational studies suggesting that the ratio should be about 1:1. This ratio also makes more physiological sense, and we suggest that in patients with massive and ongoing bleeding, it is a sensible strategy with which to start resuscitation.
Ho
Anthony M-H
AM
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong. hoamh@hotmail.com
Dion
Peter W
PW
Yeung
Janice H H
JH
Ng
Calvin S H
CS
Karmakar
Manoj K
MK
Critchley
Lester A H
LA
Rainer
Timothy H
TH
Cheung
Chi Wai
CW
Tay
Beng A
BA
D016913:Blood Component Transfusion / Q000592:standards*; D017707:Erythrocyte Transfusion; D006470:Hemorrhage / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D010949:Plasma; D012151:Resuscitation / Q000379:methods*; D012720:Severity of Illness Index; D014947:Wounds and Injuries / Q000150:complications* / Q000503:physiopathology*