Cortical gamma-oscillations modulated by visuomotor tasks: Intracranial recording in patients with epilepsy.
We determined how visuomotor tasks modulated gamma-oscillations on electrocorticography in epileptic patients who underwent epilepsy surgery. Each visual-cue consisted of either a sentence or hand gesture instructing the subject to press or not to press the button. Regardless of the recorded hemisphere, viewing sentence and gesture cues elicited gamma-augmentation sequentially in the lateral-polar occipital and inferior occipital-temporal areas; subsequently, button-press movement elicited gamma-augmentation in the Rolandic area. The magnitudes of gamma-augmentation in the Rolandic and inferior occipital-temporal areas were larger when the hand contralateral to the recorded hemisphere was used for motor responses. A double dissociation was found in the left inferior occipital-temporal cortex in one subject; the lateral portion had greater gamma-augmentation elicited by a sentence-cue, whereas the medial portion had greater gamma-augmentation elicited by a gesture-cue. The present study has increased our understanding of the physiology of the human visuomotor system.
Nagasawa
Tetsuro
T
Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit Medical Center, Detroit, Michigan 48201, USA.
Rothermel
Robert
R
Juhász
Csaba
C
Nishida
Masaaki
M
Sood
Sandeep
S
Asano
Eishi
E
D000293:Adolescent; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D003463:Cues; D004558:Electric Stimulation / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D004827:Epilepsy / Q000473:pathology* / Q000503:physiopathology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D005868:Gestures; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D007802:Language; D008297:Male; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D009483:Neuropsychological Tests; D010775:Photic Stimulation / Q000379:methods*; D012189:Retrospective Studies; D013223:Statistics as Topic; D014741:Video Recording / Q000379:methods