title: The synthesis of androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta.
abstract: Androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta were synthesized from 2alpha,3alpha,17beta-trihydroxy-5alpha-androstan-6-one after the protection of the 2alpha,3alpha-diols upon treatment with the corresponding alpha-azido acid and the subsequent deprotection of the diol grouping. Six new castasterone analogues were prepared. The biological activities were evaluated in two bioassays: a rice lamina inclination test and bean second internode bioassays. The activities of the new analogues differ in these two bioassays.
authors.affiliation: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
authors.forename: Jaroslava
authors.initials: J
authors.lastname: Hnilickova
authors.forename: Ladislav
authors.initials: L
authors.lastname: Kohout
authors.forename: Enric
authors.initials: E
authors.lastname: Capdevila
authors.forename: Ana
authors.initials: A
authors.lastname: Esteve
authors.forename: Marc
authors.initials: M
authors.lastname: Vilaplana
authors.forename: Meritxell
authors.initials: M
authors.lastname: Molist
authors.forename: Carme
authors.initials: C
authors.lastname: Brosa
authors.forename: Jana
authors.initials: J
authors.lastname: Swaczynova-Oklestkova
authors.forename: Barbora
authors.initials: B
authors.lastname: Slavikova
mesh_terms: D000731:Androstanes / Q000138:chemical synthesis* / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D004952:Esters; D006878:Hydroxides / Q000737:chemistry
chemical_list: D000731:Androstanes; D001386:Azides; D004952:Esters; D006878:Hydroxides; C031356:hydroxide ion; C033936:androstane