[Analysis of glucose levels and the risk for coronary heart disease in elderly patients in Guangzhou Haizhu district].
OBJECTIVE
To investigate the prevalence of diabetes and prediabetes and their association with the risk for coronary heart disease (CHD) in elderly residents in Haizhu District of Guangzhou.


METHODS
Stratified random sampling was employed to select a total of 1800 resident aged 50 years or older in the region. The fasting fingertip blood glucose>5.6 mmol/L was used as the criterion for the initial screening. The data were collected from qualified subjects via scheduled questionnaire surveys, blood collection and testing, and physical examination. The subjects were divided into the 3 groups, namely normal blood glucose, prediabetes, and diabetes groups. The combination rates of the relevant risk factors (hypertension, hyperlipemia, obesity, and central obesity) were compared among the groups by Framingham Heart Study to predict the occurrence of CHD in 10 years.


RESULTS
The incidence was 11.00% for prediabetes and 7.56% for diabetes in the elderly residents in Haizhu District. The occurrence of hypertension, hyperlipemia, obesity, and central obesity was significant higher in the prediabetes and diabetes group than in the normal blood glucose group, and showed no significant differences between the former two groups. The 10-year risks for CHD were markedly higher in both the prediabetes and diabetes groups than in the normal blood glucose group, but similar between the former two groups.


CONCLUSIONS
Elderly patients with prediabetes and diabetes have significantly increased 10-year risk for CHD in comparison with those with normal blood glucose, but the risk is similar between the former two groups, indicating a close association of IGR (impaired fasting glucose+ impaired fasting glucose) with CHD. Early control of blood glucose is essential to the prevention and control of CHD.
Li
Qiang
Q
Department of Cardiology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. 68574753@163.com
Chen
Ai-hua
AH
Song
Xu-dong
XD
Yan
Quan-neng
QN
Guo
Jing-bin
JB
Hao
Pei-yuan
PY
Zhou
Shan-shan
SS
Cai
De-hong
DH
D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D002681:China / Q000453:epidemiology; D003327:Coronary Disease / Q000097:blood* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012494:Sampling Studies
D001786:Blood Glucose