title: Disruption of cigarette smoking addiction after posterior cingulate damage.
abstract: The authors describe the case of a 35-year-old woman with a history of an addiction to cigarette smoking who presented with an intracerebral hemorrhage from a ruptured arteriovenous malformation. The patient reported an immediate and complete disruption of her addiction to cigarette smoking following her stroke. Structural MR imaging revealed a lesion of the posterior cingulate cortex. Neuropsychological tests showed intact cognitive functioning. This observation suggests that the posterior cingulate cortex may play a role in the addiction to cigarette smoking.
authors.affiliation: Department of Neurosurgery, Assitance Publique-Hôpitaux de Paris, Groupe Henri-Mondor Albert-Chenevier, Univ Paris 12 UPEC, Faculté de Médecine, Créteil, France. bechir@nmr.mgh.harvard.edu
authors.forename: Béchir
authors.initials: B
authors.lastname: Jarraya
authors.forename: Pierre
authors.initials: P
authors.lastname: Brugières
authors.forename: Naoki
authors.initials: N
authors.lastname: Tani
authors.forename: Jérôme
authors.initials: J
authors.lastname: Hodel
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Grandjacques
authors.forename: Gilles
authors.initials: G
authors.lastname: Fénelon
authors.forename: Philippe
authors.initials: P
authors.lastname: Decq
authors.forename: Stéphane
authors.initials: S
authors.lastname: Palfi
mesh_terms: D000328:Adult; D016739:Behavior, Addictive / Q000503:physiopathology*; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000523:psychology; D005260:Female; D006179:Gyrus Cinguli / Q000293:injuries*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations; D012422:Rupture, Spontaneous / Q000150:complications*; D012907:Smoking / Q000503:physiopathology*; D016540:Smoking Cessation; D020521:Stroke / Q000209:etiology / Q000523:psychology*