title: Solitary, extracutaneous, skull-based juvenile xanthogranuloma.
abstract: We report a case of an 18-month-old female who presented an occipital bone lesion with progressive growth. Imaging studies showed a left extradural, skull-based tumor partially occupying the posterior fossa. Histopathological and immunohistochemical studies confirmed a juvenile xanthogranuloma (JXG). Partial surgical resection, chemotherapy, and conformational radiotherapy were used. Exclusive extracutaneous JXG with an intracranial, vertebral, or skull-based localization is extremely rare.
authors.affiliation: Department of Anatomic Pathology and Neuropathology, 264 Rue Saint-Pierre, Centre Hospitalier Universitaire La Timone, 13005 Marseille, France. andre.mauesdepaula@ap-hm.fr
authors.forename: André Maues
authors.initials: AM
authors.lastname: De Paula
authors.forename: Nicolas
authors.initials: N
authors.lastname: André
authors.forename: Carla
authors.initials: C
authors.lastname: Fernandez
authors.forename: Bema
authors.initials: B
authors.lastname: Coulibaly
authors.forename: Didier
authors.initials: D
authors.lastname: Scavarda
authors.forename: Gabriel
authors.initials: G
authors.lastname: Lena
authors.forename: Corinne
authors.initials: C
authors.lastname: Bouvier
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007223:Infant; D019291:Skull Base; D016896:Treatment Outcome; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy