title: Results of percutaneous transhepatic cholecystostomy for high surgical risk patients with acute cholecystitis.
abstract: OBJECTIVE
  To assess the efficacy and safety of percutaneous transhepatic cholecystostomy (PTC) in treatment for acute cholecystitis in high surgical risk patients.
  
  
  METHODS
  A retrospective review was carried out from January 1999 to June 2007 on 23 patients, 11 males and 12 females, who underwent PTC for the management of acute cholecystitis at the Department of Surgery, Queen Mary Hospital, Hong Kong, China. The mean age of the patients was 83. They all had either clinical or radiological evidence of acute cholecystitis and had significant pre-morbid diseases. The median follow-up period on them was 35 months.
  
  
  RESULTS
  All the PTCs performed were technically successful. One patient died from procedure-related haemoperitoneum, while 87% (n = 20) of all the patients had clinical resolution of sepsis by 20 h after PTC. Eight patients underwent elective cholecystectomy afterwards (62.5% with the laparoscopic approach). Eight patients had dislodgement of the PTC catheter and one of them developed recurrent acute cholecystitis 3 months after PTC. That patient was treated conservatively. Four patients died from their pre-morbid conditions during the follow-up period.
  
  
  CONCLUSIONS
  PTC was a safe and effective alternative for treating acute cholecystitis in this group of patients. Thirteen of them without elective cholecystectomy performed did not have recurrent acute cholecystitis after a single session of PTC. It may be considered as a definitive treatment for this group of patients.
authors.affiliation: Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Hong Kong, China. kennethchok@yahoo.com.hk
authors.forename: Kenneth S H
authors.initials: KS
authors.lastname: Chok
authors.forename: Ferdinand S K
authors.initials: FS
authors.lastname: Chu
authors.forename: Tan To
authors.initials: TT
authors.lastname: Cheung
authors.forename: Vincent W T
authors.initials: VW
authors.lastname: Lam
authors.forename: Wai Key
authors.initials: WK
authors.lastname: Yuen
authors.forename: Kelvin K C
authors.initials: KK
authors.lastname: Ng
authors.forename: See Ching
authors.initials: SC
authors.lastname: Chan
authors.forename: Ronnie T P
authors.initials: RT
authors.lastname: Poon
authors.forename: Chun
authors.initials: C
authors.lastname: Yeung
authors.forename: Chung Mau
authors.initials: CM
authors.lastname: Lo
authors.forename: Sheung Tat
authors.initials: ST
authors.lastname: Fan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002408:Catheters, Indwelling; D041881:Cholecystitis, Acute / Q000601:surgery*; D002767:Cholecystostomy / Q000295:instrumentation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome