Metal trifluoromethanesulfonate-catalyzed regioselective acylation of myo-inositol 1,3,5-orthoformate.
A highly regioselective acylation of myo-inositol 1,3,5-orthoformate at the 4-O/6-O positions is catalyzed by various metal trifluoromethanesulfonates, giving excellent yields; an asymmetric example using (-)-camphanic anhydride is described here.
Padiyar
Laxmansingh T
LT
Genomics Research Center, Academia Sinica, No. 128, Section 2, Academia Road, Taipei, 11529, Taiwan.
Wen
Yuh-Sheng
YS
Hung
Shang-Cheng
SC
D000215:Acylation; D002384:Catalysis; D005561:Formates / Q000737:chemistry*; D007294:Inositol / Q000031:analogs & derivatives*; D007536:Isomerism; D008698:Mesylates / Q000737:chemistry*; D008958:Models, Molecular
D005561:Formates; D008698:Mesylates; C030544:formic acid; D007294:Inositol; C012077:trifluoromethanesulfonic acid