title: A case of congenital midline fistula of the upper lip.
abstract: Congenital fistulas of the lip are commonly found in the lower lip and accompany cleft lip. They are seen as a symptom of Van der Woude syndrome, which is predominantly hereditary. In contrast, congenital fistulas of the upper lip are rare. A number of hypotheses have been proposed to explain the pathogenesis of fistulas of the upper lip, including fusion failure of facial prominences and absence of mesoblasts, suggesting a relationship between this condition and the development of cleft lip. The pathogenesis of this disorder has been attracting attention. We report the case of a 5-year-old girl with congenital fistula of the upper lip.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Mihama-ku, Chiba, Japan. nakano@tdc.ac.jp
authors.forename: Yoko
authors.initials: Y
authors.lastname: Nakano
authors.forename: Hideki
authors.initials: H
authors.lastname: Somiya
authors.forename: Takeo
authors.initials: T
authors.lastname: Shibui
authors.forename: Takeshi
authors.initials: T
authors.lastname: Uchiyama
authors.forename: Nobuo
authors.initials: N
authors.lastname: Takano
authors.forename: Takahiko
authors.initials: T
authors.lastname: Shibahara
authors.forename: Sadamitsu
authors.initials: S
authors.lastname: Hashimoto
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007742:Labial Frenum; D008047:Lip Diseases / Q000151:congenital* / Q000601:surgery; D016155:Oral Fistula / Q000151:congenital* / Q000601:surgery; D019647:Oral Surgical Procedures / Q000295:instrumentation*