Ultrafast Grignard addition reactions in the presence of water.
The addition of allylmagnesium bromide and benzylmagnesium chloride to carbonyl compounds was investigated in the presence of protic reagents such as water and the rate of carbonyl addition was found to be comparable to the rate of protonation by the reagent.
Osztrovszky
Gyorgyi
G
Department of Chemistry, Building 201, Technical University of Denmark, DK-2800 Kgs. Lyngby. Denmark.
Holm
Torkil
T
Madsen
Robert
R