title: Treatment-resistant depression in Hispanic patients.
abstract: About one-third of patients treated with antidepressants do not respond to initial treatment, and Spanish-speaking Hispanic patients with major depression may exhibit a worse response to initial medication than English-speaking patients. Patients and clinicians should be resolute and patient as different regimens are tried throughout the course of treatment. Other options include electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation, and the medicinal food L-methylfolate.
authors.affiliation: Texas College of Osteopathic Medicine, and the Department of Psychiatry and Behavioral Health, University of North Texas Health Science Center, Fort Worth, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Podawiltz
authors.forename: Larry
authors.initials: L
authors.lastname: Culpepper
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000628:therapy*; D004351:Drug Resistance; D004565:Electroconvulsive Therapy; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D050781:Transcranial Magnetic Stimulation; D016896:Treatment Outcome; D055536:Vagus Nerve Stimulation
chemical_list: D000928:Antidepressive Agents