title: [Surgical treatment for 140 patients with gastric stromal tumors].
abstract: OBJECTIVE
  To analyze the outcome of the patients with gastric gastrointestinal stromal tumor(GIST) after surgical treatment and identify the associated risk factors.
  
  
  METHODS
  Clinical data and the tissue slices including immunohistochemistry staining of 140 patients with gastric GIST from January 1990 to December 2008 were retrospectively reviewed. SPSS 16.0 for Windows software package was used for statistical analysis.
  
  
  RESULTS
  The overall survival rates of 1-, 3-, 5-year were 96.8%, 86.7% and 79.3%, respectively. The survival rates of 1-, 3-, 5-year were 98.1%, 90.0% and 85.4% in patients who underwent complete tumor resection. But the survival rates of 1-, 3-, 5-year were 38.1%, 0 and 0 in patients with incomplete tumor resection. The differences were statistically significant (P<0.05). Gender, preoperative metastasis, tumor size,pathology type,karyokinesis, recurrence and metastasis were associated with survival rates in patients with complete tumor resection by univariate analysis. However, only tumor size, karyokinesis, recurrence and metastasis were associated with survival rates by Cox regression multivariable analysis(P<0.05).
  
  
  CONCLUSIONS
  Surgery remains the main treatment for gastric GIST. Local complete resection is the principal treatment.
authors.affiliation: Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Guangzhou 510060, China.
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Wu
authors.forename: Yu-jin
authors.initials: YJ
authors.lastname: Fang
authors.forename: Zhen-hai
authors.initials: ZH
authors.lastname: Lu
authors.forename: Jun-zhong
authors.initials: JZ
authors.lastname: Lin
authors.forename: De-sen
authors.initials: DS
authors.lastname: Wan
authors.forename: Pei-rong
authors.initials: PR
authors.lastname: Ding
authors.forename: Gong
authors.initials: G
authors.lastname: Chen
authors.forename: Li-ren
authors.initials: LR
authors.lastname: Li
authors.forename: Ling-heng
authors.initials: LH
authors.lastname: Kong
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Pan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome; D055815:Young Adult