title: "Clickable" polymer nanoparticles: a modular scaffold for surface functionalization.
abstract: The versatility of copper-catalyzed alkyne-azide coupling (CuAAC) in functionalizing drug-loaded polymer nanoparticles is demonstrated via the modification of surfaces of acetylene-functionalized PNPs with folate, biotin, and gold nanoparticles.
authors.affiliation: Department of Chemistry and The International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
authors.forename: Sai Archana
authors.initials: SA
authors.lastname: Krovi
authors.forename: DeeDee
authors.initials: D
authors.lastname: Smith
authors.forename: SonBinh T
authors.initials: ST
authors.lastname: Nguyen
mesh_terms: D000475:Alkenes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000475:Alkenes; D001386:Azides; D011108:Polymers; D006046:Gold; D003300:Copper