title: Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis.
abstract: In this study, quantitative trait locus (QTL) analysis was used to identify candidate chromosomes and for detecting the regions that include the gene or genes causing gutter-shaped root (GSR) in AKXL recombinant inbred mouse strains. One potential QTL was detected on chromosome 5 within a region of 13.0 cM, where the likelihood ratio statistic (LRS) score was higher than a suggestive level. This indicates that one of the candidate genes causing mouse GSR may be located in this region.
authors.affiliation: Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, Yokohama, Japan. Itaru-tashima@tsurumi-u.ac.jp
authors.forename: Itaru
authors.initials: I
authors.lastname: Tashima
authors.forename: Koichiro
authors.initials: K
authors.lastname: Arita
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Asada
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D008126:Lod Score; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D008963:Molar / Q000002:abnormalities*; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics; D040641:Quantitative Trait Loci / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics; D014092:Tooth Root / Q000002:abnormalities*
chemical_list: D005819:Genetic Markers