title: Familial complete androgen insensitivity syndrome with prostatic tissue and seminal vesicles.
abstract: BACKGROUND
  Complete androgen insensitivity syndrome (CAIS) is a rare androgen receptor function disorder where phenotypic female has a male genotype. They mostly present as bilateral inguinal hernias containing testes. Uterus and cervix are absent.
  
  
  METHODS
  The authors present a case of CAIS in a 22-year-old female where the presence of testes, prostatic tissue and seminal vesicles was confirmed by ultrasonography, hormonal analysis, operative findings and histopathological study. She was second of the two sisters and her elder sister was also diagnosed with CAIS.
  
  
  CONCLUSIONS
  High levels of testosterone seen in CAIS can stimulate Wolffian duct development/differentiation. Gonadectomy is advisable in such patients to avoid future neoplastic changes.
authors.affiliation: Department of Pathology, S.C.B. Medical College, Cuttack 753007, Orissa, India. kalpalata_tripathy@yahoo.co.in
authors.forename: Kalpalata
authors.initials: K
authors.lastname: Tripathy
authors.forename: Kalyaniprava
authors.initials: K
authors.lastname: Gouda
authors.forename: Pramod Kumar
authors.initials: PK
authors.lastname: Palai
authors.forename: Lucy
authors.initials: L
authors.lastname: Das
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D011467:Prostate / Q000473:pathology* / Q000601:surgery; D011944:Receptors, Androgen / Q000235:genetics*; D013737:Testis / Q000473:pathology* / Q000601:surgery; D055815:Young Adult
chemical_list: C410798:AR protein, human; D011944:Receptors, Androgen