Pigmented pleomorphic xanthoastrocytoma: a rare variant and literature review.
A 16-year-old male teenager presented with seizure and loss of consciousness for 20 min. Magnetic resonance imaging demonstrated a mass occupying the right medial temporal lobe. Histological examination revealed a non-pigmented area with spindle-shaped and large xanthomatous pleomorphic cells and a pigmented region with pigmented neoplastic cells with fascicular arrangement. Immunohistochemical studies showed the tumor was positive for GFAP and low index of Ki-67. Considering the patient's history, clinical data and pathological findings, we rendered a rare variant named pigmented pleomorphic xanthoastrocytoma.
Xiong
Ji
J
Department of Neuropathology, Institute of Neurology, Huashan Hospital of Fudan University, Shanghai, China.
Chu
Shu-Guang
SG
Mao
Ying
Y
Wang
Yin
Y
D000293:Adolescent; D001254:Astrocytoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D010858:Pigmentation
D014408:Biomarkers, Tumor