title: Fine-needle aspiration cytology of salivary gland lesions: a systematic review.
abstract: OBJECTIVE
  The aim of this study was to provide a systematic review of fine-needle aspiration (FNA) cytology on salivary gland lesions.
  
  
  METHODS
  A review of the literature was carried out using PubMed, SCIRUS, and the Cochrane Central Register of Controlled Trials (CENTRAL). The present study included only data correlating cytological and histological diagnoses.
  
  
  RESULTS
  Of the patients, 484 received a histological diagnosis of malignant tumor; cytological diagnosis was concordant in 387 (79.95%), discordant in 97 (20.04%). A total of 1,275 patients received a histological diagnosis of benign tumor; cytological diagnosis was concordant in 1,219 (95.608%) and discordant in 56 (4.39%). In all, 154 patients received a histological diagnosis of non-neoplastic lesion; cytological diagnosis was concordant in 145 (94.156%) and discordant in 9 (5.84%).
  
  
  CONCLUSIONS
  FNA is a safe diagnostic tool that has a reliable sensitivity and specificity for the assessment of salivary gland pathology. FNA cytology may be useful in routine preoperative diagnostic testing.
authors.affiliation: Department of Head and Neck Pathology, Second University of Naples, Naples, Italy. giuseppe.colella@unina2.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Colella
authors.forename: Rosangela
authors.initials: R
authors.lastname: Cannavale
authors.forename: Federica
authors.initials: F
authors.lastname: Flamminio
authors.forename: Maria P
authors.initials: MP
authors.lastname: Foschini
mesh_terms: D001707:Biopsy, Needle; D006801:Humans; D012466:Salivary Gland Diseases / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012680:Sensitivity and Specificity