title: Methadone-induced rigid-chest syndrome after substantial overdose.
abstract: We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone. The child responded to narcotic reversal. Pediatric physicians should be aware of this possible complication.
authors.affiliation: Pediatric Critical Care, St John's Mercy Children's Hospital, Creve Coeur, MO 63141, USA. robert.lynch2@mercy.net
authors.forename: Robert E
authors.initials: RE
authors.lastname: Lynch
authors.forename: Richard A
authors.initials: RA
authors.lastname: Hack
mesh_terms: D004334:Drug Administration Schedule; D062787:Drug Overdose / Q000150:complications* / Q000175:diagnosis; D005283:Fentanyl / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D008508:Medication Errors; D008691:Methadone / Q000008:administration & dosage*; D009127:Muscle Rigidity / Q000139:chemically induced* / Q000503:physiopathology; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000139:chemically induced* / Q000503:physiopathology; D018570:Risk Assessment; D013577:Syndrome; D035441:Thoracic Wall / Q000503:physiopathology*
chemical_list: D008691:Methadone; D005283:Fentanyl