title: [Which one to choose for the first antihypertensive drug?].
abstract: All pivotal groups of antihypertensive drugs improve the prognosis of hypertensive patients. The status of renin-angiotensin system inhibitors as the first-line drug has become established in high-risk patients. Antihypertensive efficacy of various drugs varies individually due to the diversity of the background of hypertension and the heterogeneous nature of essential hypertension, whereby choice of the first-line drug is made on an individual basis. The selection involves consideration of predictive evidence of possible target organ alterations and associated diseases with various drug classes on one hand and factors affecting the patient's individual blood pressure response on the other hand.
authors.affiliation: HYKS, medisiininen tulosyksikkö, nefrologian klinikka ja Helsinki Hypertension Centre of Excellence, PL 340, 00029 HUS.
authors.forename: Ilkka
authors.initials: I
authors.lastname: Tikkanen
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003657:Decision Making; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D012084:Renin-Angiotensin System / Q000187:drug effects*
chemical_list: D000959:Antihypertensive Agents