Infection status of hospitalized diarrheal patients with gastrointestinal protozoa, bacteria, and viruses in the Republic of Korea.
To understand protozoan, viral, and bacterial infections in diarrheal patients, we analyzed positivity and mixed-infection status with 3 protozoans, 4 viruses, and 10 bacteria in hospitalized diarrheal patients during 2004-2006 in the Republic of Korea. A total of 76,652 stool samples were collected from 96 hospitals across the nation. The positivity for protozoa, viruses, and bacteria was 129, 1,759, and 1,797 per 10,000 persons, respectively. Especially, Cryptosporidium parvum was highly mixed-infected with rotavirus among pediatric diarrheal patients (29.5 per 100 C. parvum positive cases), and Entamoeba histolytica was mixed-infected with Clostridium perfringens (10.3 per 100 E. histolytica positive cases) in protozoan-diarrheal patients. Those infected with rotavirus and C. perfringens constituted relatively high proportions among mixed infection cases from January to April. The positivity for rotavirus among viral infection for those aged < or = 5 years was significantly higher, while C. perfringens among bacterial infection was higher for > or = 50 years. The information for association of viral and bacterial infections with enteropathogenic protozoa in diarrheal patients may contribute to improvement of care for diarrhea as well as development of control strategies for diarrheal diseases in Korea.
Cheun
Hyeng-Il
HI
Department of Malaria and Parasitic Diseases, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Seoul, Korea. ilcheun7@korea.kr
Cho
Shin-Hyeong
SH
Lee
Jin-Hee
JH
Lim
Yi-Young
YY
Jeon
Ji-Hye
JH
Yu
Jae-Ran
JR
Kim
Tong-Soo
TS
Lee
Won-Ja
WJ
Cho
Seung-Hak
SH
Lee
Deog-Yong
DY
Park
Mi-Seon
MS
Jeong
Hye-Sook
HS
Chen
Doo-Sung
DS
Ji
Yeong-Mi
YM
Kwon
Mi-Hwa
MH
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003967:Diarrhea / Q000453:epidemiology* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D056890:Eukaryota / Q000145:classification / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011528:Protozoan Infections / Q000453:epidemiology* / Q000469:parasitology; D056910:Republic of Korea / Q000453:epidemiology; D014777:Virus Diseases / Q000453:epidemiology* / Q000821:virology; D014780:Viruses / Q000145:classification / Q000302:isolation & purification; D055815:Young Adult