TGF-beta receptors PAR-ticipate in axon formation.
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (2010) provide striking evidence that TGF-beta signaling via the Par polarity complex is required for axon formation by neocortical pyramidal neurons.
Dwyer
Noelle D
ND
Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA. ndwyer@virginia.edu
Winckler
Bettina
B