title: Digestive Disease Week 2010. Turning Science into Medicine--part 2.
abstract: The Digestive Disease Week 2010 conference, held in New Orleans, included topics covering new therapeutic developments in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. This conference report highlights selected presentations on the apolipoprotein E-mimetic peptide COG-112 (Cognosci Inc) for the potential treatment of Citrobacter rodentium-induced colitis; the inhibition of sphingosine kinase with ABC-294640 (Apogee Biotechnology Corp) to alleviate stress after hepatic ischemia-reperfusion injury; TLR4 targeting with NI-0101 (NovImmune SA) to prevent colitis-associated cancer; immunization against TNF with TNFalpha kinoid (Neovacs SA) for the treatment of patients with Crohn's disease; and preclinical studies with the anti-inflammatory agent minnelide (University of Minnesota) for the treatment of pancreatic cancer.
authors.affiliation: Thomson Reuters, 77 Hatton Garden, London, EC1N 8JS, UK. lisa.hodgkinson@thomsonreuters.com
authors.forename: Lisa
authors.initials: L
authors.lastname: Hodgkinson
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D004066:Digestive System Diseases / Q000188:drug therapy* / Q000276:immunology / Q000628:therapy; D004353:Drug Evaluation, Preclinical; D015507:Drugs, Investigational / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007114:Immunization
chemical_list: D015507:Drugs, Investigational