title: [Features of preoperative contrast-enhanced ultrasound of breast cancer: relationship with the syndrome classification in traditional Chinese medicine].
abstract: OBJECTIVE
  To analyze the relationship between the features of preoperative contrast-enhanced ultrasound and the differentiation of symptoms and signs for syndrome classification by traditional Chinese medicine (TCM).
  
  
  METHODS
  Eighty-two patients with malignant breast tumor were examined with contrast-enhanced ultrasound before the operation. The tumor diameter was greater than 2.0 cm in 48 cases and below 2.0 cm in 34 cases. According to the curative effect standard of TCM disorder, differentiation of symptoms and signs for classification of syndrome were performed, and the ultrasonic manifestations of different syndrome types were compared.
  
  
  RESULTS
  In patients with maximum tumor diameter < or = 2 cm, Chong and Ren disorder type and liver Qi stagnation type were prevalent. In those with tumor diameter of <2 cm, Zeyi liver Qi stagnation type and virtual drug junction were more common. The mass peak intensity, slope of increase, enhancement intensity index and time-intensity curve of ultrasound differed significant between different syndrome types (P<0.05).
  
  
  CONCLUSIONS
  The preoperative ultrasound features of breast cancer are associated with the syndrome types in TCM.
authors.affiliation: Department of Ultrasound, Second Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510120, China. Seeyaya @tom.com
authors.forename: Li-shan
authors.initials: LS
authors.lastname: Cai
authors.forename: Jian-xing
authors.initials: JX
authors.lastname: Zhang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Shen
authors.forename: Hong-lin
authors.initials: HL
authors.lastname: Situ
authors.forename: Guang-hui
authors.initials: GH
authors.lastname: Song
authors.forename: Yin-chang
authors.initials: YC
authors.lastname: Xie
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000145:classification / Q000000981:diagnostic imaging*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D057234:Preoperative Period; D014463:Ultrasonography
chemical_list: D003287:Contrast Media