title: Health-related quality of life in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome.
abstract: OBJECTIVE
  To examine the health-related quality of life (HRQoL) and factors associated with HRQoL in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using two generic preference-based HRQoL instruments, EQ-5D (plus EQ-VAS) and SF-6D, with the results compared with general population.
  
  
  METHODS
  CP/CPPS patients were recruited from two tertiary referral hospitals, and the general populations were randomly approached. After informed consent, subjects were interviewed using EQ-5D, EQ-VAS and SF-6D, and their socio-demographic and medical information was solicited.
  
  
  RESULTS
  Compared to the general population (n = 364), CP/CPPS patients (n = 268) reported significantly worse HRQoL with median score of the EQ-5D utility index (0.73 vs. 0.85), SF-6D utility index (0.76 vs. 0.81), and EQ-VAS (70.0 vs. 85.0). Multiple linear regression analyses showed pain symptom had the strongest predictive power for HRQoL, compared to symptom duration and urinary symptom. Socio-demographic factors and comorbidities did not significantly contribute to poorer HRQoL.
  
  
  CONCLUSIONS
  CP/CPPS patients experienced deteriorated HRQoL with lower health-related utility scores compared to general population, and pain severity was the main physical symptom predicting decreased health-related utility. Further studies are needed to provide the reference utility index for the comparison and better characterizing the influence of geographic and cultural factors on variation of health-related utility of CP/CPPS patients.
authors.affiliation: Discipline of Pharmacy & Experimental Pharmacology, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW 2308, Australia.
authors.forename: Fei-Li
authors.initials: FL
authors.lastname: Zhao
authors.forename: Ming
authors.initials: M
authors.lastname: Yue
authors.forename: Hua
authors.initials: H
authors.lastname: Yang
authors.forename: Tian
authors.initials: T
authors.lastname: Wang
authors.forename: Jiu-Hong
authors.initials: JH
authors.lastname: Wu
authors.forename: Shu-Chuen
authors.initials: SC
authors.lastname: Li
mesh_terms: D000328:Adult; D002681:China / Q000208:ethnology; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011472:Prostatitis / Q000523:psychology*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult