title: Prevalence of malignant disorders in 50 cases of postmenopausal bleeding.
abstract: OBJECTIVE
  To find the prevalence of malignant pathology in women with postmenopausal bleeding (PMB).
  
  
  METHODS
  An observational cross section study was conducted in the Department of Obstetrics and Gynaecology at Peoples Medical College and Hospital Nawabshah from 1st January 2006 to 31st December 2006. All patients with a typical history of post-menopausal bleeding were evaluated under anaesthesia and diagnostic dilatation and curettage was done for histopathological assessment of endometrial lining. Cervical biopsy was taken in selected patients.
  
  
  RESULTS
  Total 50 patients were included. Benign lesion was found in 24 (48%) cases, followed by malignant pathology in 15 (30%), premalignant lesion was responsible for PMB in 7 (14%) cases, while pathology remained undetermined in 4 (8%) patients.
  
  
  CONCLUSIONS
  Malignancy has an important role in the etiology of PMB which needs a careful evaluation. This study showed a high prevalence of malignant disorders (30%) with carcinoma of cervix and endometrium having an equal contribution. Multiparity was the most significant factor for carcinoma of endometrium.
authors.affiliation: Peoples Medical College, Nawabshah, Sindh.
authors.forename: Kauser
authors.initials: K
authors.lastname: Jillani
authors.forename: Razia Bahadur
authors.initials: RB
authors.lastname: Khero
authors.forename: Safia
authors.initials: S
authors.lastname: Maqsood
authors.forename: Maqsood Ahmed
authors.initials: MA
authors.lastname: Siddiqui
mesh_terms: D003430:Cross-Sectional Studies; D016889:Endometrial Neoplasms / Q000453:epidemiology; D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D015995:Prevalence; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology; D014592:Uterine Hemorrhage / Q000453:epidemiology* / Q000209:etiology*