Electrically assisted solid-phase microextraction combined with liquid chromatography-mass spectrometry for determination of parathion in water.
A novel method for electrically assisted microextraction coupled to liquid chromatography-mass spectrometry was evaluated for determination of trace levels of parathion in water. A pencil lead electrode was used in a di-electrode system to extract parathion onto the electrode surface with a reductive potential applied. The optimum extraction conditions were found to be a potential of -600 mV for 60s in pH 2 phosphate buffer solution. The parathion was desorbed statically for 1 min and dynamically for 3 min in the commercial SPME-HPLC desorption chamber, then analyzed with LC-APCI-MS/MS. The detection limit (LOD) for parathion in water was found to be 0.3 ng/mL. The proposed technique was demonstrated to be fast, sensitive and not require a solvent sample pretreatment.
Yang
Tzung-Jie
TJ
Department of Chemistry, National Chung Hsing University, Taichung, Taiwan.
Lee
Maw-Rong
MR
D002853:Chromatography, Liquid / Q000379:methods; D004560:Electricity; D004784:Environmental Monitoring; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D010278:Parathion / Q000032:analysis* / Q000737:chemistry; D052617:Solid Phase Microextraction / Q000379:methods; D014867:Water / Q000737:chemistry*
D014867:Water; D010278:Parathion