title: Xanthogranuloma of the sellar region--case report.
abstract: A 55-year-old woman presented with a rare xanthogranuloma of the sellar region after complaining of severe headache and visual disturbance 3 months previously. Clinical examination showed she was alert with early signs of bitemporal hemianopsia. Endocrinological examination revealed hypopituitarism. Magnetic resonance imaging showed an intrasellar mass extending into the suprasellar region and compressing the optic chiasma, which appeared homogeneously hyperintense on T(1)-weighted images. Endonasal transsphenoidal resection of the tumor was performed. Histological examination disclosed granulomatous tissue with cholesterol clefts, hemosiderin deposits, fibrous tissues, and macrophages containing rich fat. The histological diagnosis was xanthogranuloma of the sellar region. Her visual symptoms recovered postoperatively although the hypopituitarism remained. Xanthogranuloma of the sellar region is rare, but must be considered in the differential diagnosis of tumors of the sellar region.
authors.affiliation: Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Arai
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Nishihara
authors.forename: Takashi
authors.initials: T
authors.lastname: Sasayama
authors.forename: Hideo
authors.initials: H
authors.lastname: Aihara
authors.forename: Kohkichi
authors.initials: K
authors.lastname: Hosoda
authors.forename: Tomoo
authors.initials: T
authors.lastname: Itoh
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Sakagami
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kuwamura
authors.forename: Eiji
authors.initials: E
authors.lastname: Kohmura
mesh_terms: D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D008875:Middle Aged; D011859:Radiography; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D019292:Skull Base Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D016896:Treatment Outcome; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000601:surgery