Ocular malformation in a newborn secondary to maternal hypovitaminosis A.
We report a case of microphthalmia, inferior adherent leukoma, and optic nerve hypoplasia in an infant whose mother underwent biliopancreatic diversion surgery for obesity 7 years before his birth. The pregnancy was complicated by severe, maternal hypovitaminosis A despite oral supplementation. The infant was found to have undetectable serum vitamin A levels in the perinatal period. At 8 weeks of age, the infant underwent sector iridectomies. At 9 months of age, electroretinography suggested rod dysfunction. His visual performance is poor.
Gilchrist
Hannah
H
Department of Ophthalmology, Royal Children's Hospital, Brisbane, Queensland, Australia.
Taranath
Deepa A
DA
Gole
Glen A
GA
D005124:Eye Abnormalities / Q000209:etiology*; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009755:Night Blindness / Q000209:etiology; D009767:Obesity, Morbid / Q000601:surgery*; D011247:Pregnancy; D011248:Pregnancy Complications; D011297:Prenatal Exposure Delayed Effects / Q000209:etiology*; D014802:Vitamin A Deficiency / Q000150:complications* / Q000209:etiology