Iridium-catalyzed annulation of N-arylcarbamoyl chlorides with internal alkynes.
An iridium complex successfully catalyzed the annulation of various N-arylcarbamoyl chlorides with internal alkynes to afford 2-quinolones in good to excellent yields. The present reaction is widely applicable to substrates with various functionalities. An amide-iridacycle complex was isolated, and it is likely that such an iridacycle species is a key intermediate in the catalytic reaction.
Iwai
Tomohiro
T
Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.
Fujihara
Tetsuaki
T
Terao
Jun
J
Tsuji
Yasushi
Y
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D014961:X-Ray Diffraction
D000480:Alkynes; D002712:Chlorides; D007495:Iridium