[Anti-Müllerian hormone: player and marker of folliculogenesis].
All indicates that anti-Müllerian hormone (AMH), though initially studied for its importance on male development, plays an inhibiting role on the initial and cyclic processes of follicular recruitment. The aspects involved in its regulation are still poorly understood, but the oocyte, some steroids, and follicular development itself seem to be involved. In addition, AMH has become an important clinical marker of ovarian functioning for many reasons, including its exclusive production by granulosa follicles at many stages of development, its probable FSH independence, its low inter and intracycle variability and its reliable quantitative (qualitative?) relationship with ovarian follicles and their response to exogenous FSH. The growing interest in ovarian AMH incited us to review some important fundamental and clinical publications in this field.
da Silva
A-L Berwanger
AL
Service de gynécologie-obstétrique et médecine de la reproduction, Inserm U782, hôpital Antoine-Béclère, AP-HP, université Paris-Sud, Clamart, France.
Even
M
M
Grynberg
M
M
Gallot
V
V
Frydman
R
R
Fanchin
R
R
D000818:Animals; D054304:Anti-Mullerian Hormone / Q000235:genetics / Q000502:physiology*; D015415:Biomarkers; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D008297:Male; D009865:Oocytes / Q000502:physiology; D006080:Ovarian Follicle / Q000502:physiology*; D010053:Ovary / Q000502:physiology; D010062:Ovulation Induction
D015415:Biomarkers; D054304:Anti-Mullerian Hormone