[Effects of continuous blood purification on hemodynamics and oxygenation in patients with acute respiratory distress syndrome].
OBJECTIVE
To evaluate the effects of continuous blood purification on the hemodynamics and oxygenation in patients with acute respiratory distress syndrome (ARDS).


METHODS
Twenty-one patients with ARDS were treated with continuous veno-venous hemofiltration (CVVH) combined with plasma exchange. Hemodynamics and oxygenation were measured or calculated at scheduled intervals using Swan-Ganz catheters.


RESULTS
The mean arterial pressure, partial pressure of arterial oxygen, oxygen delivery, oxygen consumption increased, heart rate, mean pulmonary arterial pressure, pulmonary capillary wedge pressure, blood lactate concentration all decreased significantly after the treatment, and the oxygen extraction ratio underwent no obvious changes.


CONCLUSIONS
Continuous blood purification can increase blood and oxygen supply but has no significant effects on oxygen extraction ratio in ARDS patients.
Liang
Xue-ling
XL
Department of Emergency, Zhongshan People's Hospital, Hospital, Zhongshan 528437, China. lianxueling020504@163.com
Jian
Chong-hui
CH
Lu
Pin-duan
PD
Zheng
Huan-cheng
HC
D000328:Adult; D005260:Female; D006439:Hemodynamics; D006440:Hemofiltration / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000502:physiology*; D010313:Partial Pressure; D010951:Plasma Exchange / Q000379:methods*; D011659:Pulmonary Gas Exchange; D012128:Respiratory Distress Syndrome / Q000628:therapy*
D010100:Oxygen