Esophageal metastasis from occult lung cancer.
A 66-year-old man with dysphagia was found to have a poorly differentiated esophageal carcinoma by incision biopsy. Following esophagectomy, reconstruction with a gastric tube was performed. Pathological examination and immunohisto-chemistry showed infiltration of adenocarcinoma cells with positive thyroid transcription factor 1-staining in the submucosal layer, which indicated metastatic esophageal carcinoma. Although no pulmonary lesion could be visualized by imaging or bronchoscopy, pulmonary origin was highly suspected as a result of positive thyroid transcription factor 1-staining. To the best of our knowledge, this is the first reported case of metastatic esophageal carcinoma from occult lung cancer (AJCC TNM stage TX).
Hsu
Po-Kuei
PK
Department of Surgery, Chutung Veterans Hospital, Hsinchu, Taipei, Taiwan, ROC. hsupokuei@yahoo.com.tw
Shai
Sen-Ei
SE
Wang
John
J
Hsu
Chung-Ping
CP
D000368:Aged; D004268:DNA-Binding Proteins / Q000032:analysis; D004938:Esophageal Neoplasms / Q000737:chemistry / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D014157:Transcription Factors
D004268:DNA-Binding Proteins; C504003:TTF1 protein, human; D014157:Transcription Factors