title: Primary central nervous system peripheral T-cell lymphoma in a child.
abstract: A 10-year-old Caucasian boy was admitted to the hospital with a 3-month history of headache, vomiting, ataxia, and right amaurosis. A magnetic resonance imaging (MRI) showed a solid, expansive, parasagittal mass in the right parietal hemisphere that extended sagitally to include the optical chiasm. The lesion was considered unresectable. Histology and immunophenotyping of biopsy tissue revealed characteristics of peripheral T-cell lymphoma. No other anatomical region, including bone marrow, was compromised. Primary T-cell lymphomas of the central nervous system are rare, especially in childhood. Here, we describe the rapidly deteriorating and fatal clinical course of a boy with a primary T-cell lymphoma in the central nervous system.
authors.affiliation: Consultoria em Patologia, Botucatu-SP, Brazil.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Gualco
authors.forename: Sheila
authors.initials: S
authors.lastname: Wludarski
authors.forename: Luciana
authors.initials: L
authors.lastname: Hayashi-Silva
authors.forename: Plinio
authors.initials: P
authors.lastname: Medeiros Filho
authors.forename: Geni
authors.initials: G
authors.lastname: Veras
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Bacchi
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D002648:Child; D017809:Fatal Outcome; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral / Q000378:metabolism / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D014408:Biomarkers, Tumor