title: Limb salvage operation using intraoperative extracorporeal autogenous irradiated bone and tendon graft for myxoid liposarcoma on dorsum of foot.
abstract: Foot and ankle sarcomas are conventionally treated with amputation. In this article, we report a case of myxoid liposarcoma on the dorsum of the foot treated by limb salvage operation with intraoperative extracorporeal autogenous irradiated bone and tendon grafts. The patient was a 76-year-old woman with a soft tissue tumor beneath the extensor tendons with attachment to the tarsal and metatarsal bones. The histological diagnosis was myxoid liposarcoma. Wide margin was achieved by splitting the tarsal and metatarsal bones into dorsal and plantar parts. The dorsal part of the bones and tendons was isolated from the resected material, irradiated ex-vivo and re-implanted into the host's bones and tendons. No local recurrence was detected around the irradiated bones and tendons during the follow-up at 36 months. The functional rating was 74% according to the ISOLS rating system. This method may be a better procedure for limb salvage operation of sarcomas on the dorsum of the foot.
authors.affiliation: Department of Orthopaedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1-3-3, Nakamichi, Higashinari-ku, Osaka 537-8511, Japan.
authors.forename: Ritsuro
authors.initials: R
authors.lastname: Ozaki
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hamada
authors.forename: Makoto
authors.initials: M
authors.lastname: Emori
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Omori
authors.forename: Susumu
authors.initials: S
authors.lastname: Joyama
authors.forename: Norifumi
authors.initials: N
authors.lastname: Naka
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tomita
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Araki
mesh_terms: D000368:Aged; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005534:Foot Diseases / Q000601:surgery*; D006801:Humans; D023821:Limb Salvage / Q000379:methods; D018208:Liposarcoma, Myxoid / Q000532:radiotherapy* / Q000601:surgery*; D008682:Metatarsal Bones / Q000528:radiation effects / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000601:surgery*; D013639:Tarsal Bones / Q000528:radiation effects / Q000601:surgery; D013710:Tendons / Q000637:transplantation*; D014182:Transplantation, Autologous