title: (99m)Tc-labeled-1-thio-beta-d-glucose as a new tool to temporomandibular joint inflammatory disorders diagnosis.
abstract: OBJECTIVE
  The aim of this study was to evaluate early detection of temporomandibular joint (TMJ) inflammatory changes based on 1-thio-beta-d-glucose radiolabeled with technetium-99m.
  
  
  METHODS
  The method applied a TMJ inflammation model in rats followed by radiopharmaceutical synthesis, intravenous administration of (99m)Tc-1-TG and kinetic scintigraphy imaging.
  
  
  RESULTS
  Results show a significant difference of (99m)Tc-1-TG uptake between inflamed TMJ and the control joint. The biodistribution of (99m)Tc-1-TG by images showed the kidneys' excretion.
  
  
  CONCLUSIONS
  As conclusion, (99m)Tc-1-TG is a helpful tool in TMJ inflammatory process detection.
authors.affiliation: Departamento de Engenharia Nuclear--PCA, Escola de Engenharia, Universidade Federal de Minas Gerais (UFMG)--Avenida Presidente Antônio Carlos, 6627, CEP: 31270-100 Belo Horizonte, MG, Brazil. cbbrasileiro@gmail.com
authors.forename: Cláudia Borges
authors.initials: CB
authors.lastname: Brasileiro
authors.forename: Cinthia Mara da Fonseca
authors.initials: CM
authors.lastname: Pacheco
authors.forename: Celso Martins
authors.initials: CM
authors.lastname: Queiroz-Junior
authors.forename: Carla Flávia
authors.initials: CF
authors.lastname: de Lima
authors.forename: Juliana Batista
authors.initials: JB
authors.lastname: da Silva
authors.forename: Tarcísio Passos Ribeiro
authors.initials: TP
authors.lastname: de Campos
mesh_terms: D000818:Animals; D005947:Glucose / Q000008:administration & dosage* / Q000737:chemistry; D008297:Male; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D051381:Rats; D013705:Temporomandibular Joint Disorders / Q000175:diagnosis*
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D005947:Glucose