title: Campylobacter spp among children with acute diarrhea attending Mulago hospital in Kampala--Uganda.
abstract: BACKGROUND
  Campylobacter infections occur worldwide. A recent study in Kampala, Uganda, found that 87% of broiler chickens had Campylobacter jejuni; these are potential source of human infection. Isolation rate in developing countries is between 5-35%. This study aimed at finding prevalence of children with campylobacter infection among children with acute diarrhea attending Mulago hospital.
  
  
  OBJECTIVE
  The objective was to establish the proportion of children infected with Campylobacter spp among children with acute diarrhea at Mulago hospital.
  
  
  METHODS
  A crossectional study from July to October 2005 was conducted involved 226 children with acute diarrhea. Serial sampling was done a total of 226 stool specimens were obtained and cultured on selective media. Identification was done using biochemical test and susceptibility using standard discs diffusion method.
  
  
  RESULTS
  Campylobacter spp were isolated in 21 (9.3%) of 226 stool specimens analyzed. Campylobacter jejuni 17 (80.9%), Campylobacter lari 2 (9.5%), Campylobacter coli 1 (4.5%) and Campylobacter jejuni/coli 1(4.5%). All Campylobacter isolates were sensitive to erythromycin, and 20% had intermediate resistance to Ampicillin.
  
  
  CONCLUSIONS
  Campylobacter spp are prevalent among children with acute diarrhea in Kampala- Uganda. A large multicenter study should be undertaken so that the extent of campylobacter infection in our setting can be established.
authors.affiliation: Department of Medical Microbiology Makerere University College of Health Sciences, Kampala Uganda. mshana72@yahoo.com
authors.forename: S E
authors.initials: SE
authors.lastname: Mshana
authors.forename: M
authors.initials: M
authors.lastname: Joloba
authors.forename: A
authors.initials: A
authors.lastname: Kakooza
authors.forename: D
authors.initials: D
authors.lastname: Kaddu-Mulindwa
mesh_terms: D000208:Acute Disease; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002167:Campylobacter / Q000187:drug effects / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D014454:Uganda / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents