title: Successful treatment of a chronic facial abscess using a prolonged release antibiotic copolymer in a golden lion tamarin (Leontopithecus rosalia).
abstract: A 3-yr-old, female captive golden lion tamarin (Leontopithecus rosalia) developed an abscess initially within the oral cavity that progressed to the cheek. Treatment with amoxicillin/clavulanic acid, enrofloxacin, and sulfamethoxizole/trimethoprim resulted in temporary resolution of the abscess. Cultures from the abscess included Escherichia coli, Enterobacter cloacae, hemolytic Staphylococcus, and Serratia marcescens. Histopathology was consistent with chronic cellulitis. Ceftazidime mixed with a thermoreversable polymer gel was surgically placed in the wound to provide long-term local antibiotic therapy. This provided complete resolution of infection without the need for additional surgical procedures.
authors.affiliation: Roger Williams Park Zoo, 1000 Elmwood Avenue, Providence, Rhode Island 02907, USA. mmcbride@rwpzoo.org
authors.forename: Michael
authors.initials: M
authors.lastname: McBride
authors.forename: Cheryl
authors.initials: C
authors.lastname: Cullion
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002442:Ceftazidime / Q000008:administration & dosage* / Q000627:therapeutic use*; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D005260:Female; D051039:Leontopithecus; D008992:Monkey Diseases / Q000188:drug therapy*; D020442:Poloxamer
chemical_list: D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D020442:Poloxamer; D002442:Ceftazidime