title: A need for basic research on fluid-based early detection biomarkers.
abstract: Cancer continues to be a major cause of mortality despite decades of effort and expense. The problem reviewed here is that before many cancers are discovered they have already progressed to become drug resistant or metastatic. Biomarkers found in blood or other body fluids could supplement current clinical indicators to permit earlier detection and thereby reduce cancer mortality.
authors.affiliation: Bioarray Therapeutics Inc., Belmont, Massachusetts, USA.
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Martin
authors.forename: Marcia V
authors.initials: MV
authors.lastname: Fournier
authors.forename: G Prem Veer
authors.initials: GP
authors.lastname: Reddy
authors.forename: Arthur B
authors.initials: AB
authors.lastname: Pardee
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis* / Q000378:metabolism; D042241:Early Diagnosis; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor