Rational design of efficient rhodium catalysts for the anti-Markovnikov oxidative amination of styrene.
Cationic rhodium(I) complexes containing the flexible hemilabile phosphine ligand (3-ethoxypropyl)diphenylphosphine efficiently catalyzed the anti-Markovnikov oxidative amination of styrene in tetrahydrofurane at 80 degrees C to produce (E)-1-styrylpiperidine with turnover frequencies up to 75 h(-1) with excellent enamine selectivity (96%).
Jiménez
M Victoria
MV
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-C.S.I.C., 50009-Zaragoza, Spain. vjimenez@unizar.es
Pérez-Torrente
Jesús J
JJ
Bartolomé
M Isabel
MI
Lahoz
Fernando J
FJ
Oro
Luis A
LA