title: Seven years of recording from monkey cortex with a chronically implanted multiple microelectrode.
abstract: A brush of 64 microwires was chronically implanted in the ventral premotor cortex of a macaque monkey. Contrary to common approaches, the wires were inserted from the white matter side. This approach, by avoiding mechanical pressure on the dura and pia mater during penetration, disturbed only minimally the cortical recording site. With this approach isolated potentials and multiunit activity were recorded for more than 7 years in about one-third of electrodes. The indirect insertion method also provided an excellent stability within each recording session, and in some cases even allowed recording from the same neurons for several years. Histological examination of the implanted brain region shows only a very marginal damage to the recording area. Advantages and problems related to long-term recording are discussed.
authors.affiliation: Dipartimento di Neuroscienze, Università di Parma Parma, Italy.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Krüger
authors.forename: Fausto
authors.initials: F
authors.lastname: Caruana
authors.forename: Riccardo Dalla
authors.initials: RD
authors.lastname: Volta
authors.forename: Giacomo
authors.initials: G
authors.lastname: Rizzolatti