title: Extra- and intra-articular synovial chondromatosis and malignant transformation to chondrosarcoma.
abstract: Intra- and extra-articular primary synovial chondromatosis (SC) was observed in a five-year-old, entire male German Shepherd. Thousands of small cartilaginous nodules were removed from the stifle joint as well as from several adjacent muscles. Diagnosis of SC was established based on clinical, radiographic and biopsy results. The owner declined to have a new surgery performed for complete nodule removal and partial synovectomy. Nine months after the initial presentation, a proximal pathological intra- articular tibial fracture was observed and malignant transformation to chondrosarcoma was diagnosed after limb amputation. No metastasis was observed after 1.5 years of follow-up.
authors.affiliation: Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Campus Edificio V, Universidad Autónoma de Barcelona, Bellaterra, Barcelona 08193, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Díaz-Bertrana
authors.forename: I
authors.initials: I
authors.lastname: Durall
authors.forename: J M
authors.initials: JM
authors.lastname: Rial
authors.forename: J
authors.initials: J
authors.lastname: Franch
authors.forename: P
authors.initials: P
authors.lastname: Fontecha
authors.forename: A
authors.initials: A
authors.lastname: Ramis
mesh_terms: D000671:Amputation, Surgical / Q000662:veterinary; D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D019902:Chondrocytes / Q000473:pathology; D018210:Chondromatosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000662:veterinary; D015838:Chondromatosis, Synovial / Q000000981:diagnostic imaging / Q000473:pathology* / Q000662:veterinary; D002813:Chondrosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D004285:Dogs; D007794:Lameness, Animal / Q000209:etiology / Q000473:pathology; D008297:Male; D011859:Radiography; D013264:Stifle / Q000000981:diagnostic imaging / Q000473:pathology; D013583:Synovial Membrane / Q000473:pathology