Salmonella pyomyositis complicating sickle cell anemia: a case report.
BACKGROUND
Pyomyositis is a bacterial infection of skeletal muscle and a rare complication of sickle cell anemia. It may present a difficult problem in diagnosis, leading to delay in appropriate treatment and development of complications including abscess formation and osteomyelitis.


METHODS
We report the case of a 44-year-old Afro-Caribbean woman with homozygous sickle cell disease who presented with chest crisis and later developed pyomyositis of her hip and pelvic muscles. Salmonella agbeni was isolated from blood cultures and magnetic resonance imaging confirmed the diagnosis in this case. It is noteworthy of this case that there were no antecedent signs of gastroenteritis. Drainage was not appropriate and she was treated with intravenous antibiotics for six weeks.


CONCLUSIONS
Focal Salmonella infections are uncommon in soft tissue. Pyomyositis should be considered in patients with sickle cell anemia that continue to have muscle pain and high fevers, despite initial management of their sickle cell crisis. Radiological imaging, particularly magnetic resonance imaging, is a crucial tool in establishing the diagnosis.
Wong
Vanessa K
VK
Department of Microbiology, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK. vanessawong@doctors.org.uk.
Lissack
Maxine E
ME
Turmezei
Tom D
TD
Maitland
Jenny A
JA