title: Importance of screening serological examination of umbilical blood and the blood of the mother for timely diagnosis of congenital toxoplasmosis and toxocariasis.
abstract: OBJECTIVE
  Parasitic diseases, particularly the congenital form of toxoplasmosis, can negatively affect the mortality and morbidity of newborns and infants.
  
  
  METHODS
  The authors examined 152 samples of umbilical blood in 152 women who had experienced premature delivery with or without PROM. The samples were examined for the titre of antibodies - the CFR, levels of immunoglobulins IgA and IGM (toxoplasmosis) and for titres of antibodies against toxocariasis.
  
  
  RESULTS
  No presence of IGM was demonstrated in association with the congenital form of toxoplasmosis. The values of titres of antibodies against toxocariasis were negative. There was only one case of a titre in a newborn higher than that in the mother. There was no clinical manifestation of the disease.
  
  
  CONCLUSIONS
  In spite of the negative result, the authors point out the possibility of a timely diagnosis of these parasitic diseases.
authors.affiliation: University of South Bohemia in Ceské Budejovice, Faculty of Health and Social Studies, Department of Clinical Branches, Ceské Budejovice, Czech Republic. mveleminsky@tbn.cz
authors.forename: Milos
authors.initials: M
authors.lastname: Veleminsky
authors.forename: Milos
authors.initials: M
authors.lastname: Veleminsky
authors.forename: Karel
authors.initials: K
authors.lastname: Fajfrlik
authors.forename: Libuse
authors.initials: L
authors.lastname: Kolarova
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D036801:Parturition / Q000097:blood*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D012698:Serologic Tests / Q000379:methods; D017166:Toxocara canis / Q000276:immunology*; D014120:Toxocariasis / Q000097:blood* / Q000175:diagnosis* / Q000276:immunology; D014125:Toxoplasmosis, Congenital / Q000097:blood* / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007075:Immunoglobulin M