title: Non-pulsatile circulation with axial-flow left ventricular assist device preserves neurocognitive function.
abstract: Concerns about the potential impact of the non-pulsatile circulation pattern generated by the new generation axial-flow left ventricular assist devices on neurocognitive function led us to evaluate a patient in whom a Jarvik 2000 pump was implanted. We assessed the patient's baseline neurocognitive function preoperatively as well as at 1-month and 6-month follow-up, using a comprehensive battery of neuropsychological tests. A slight improvement in circumscribed neurocognitive domains was noted, with no evidence of further decline at the end of a 6-month follow-up period.
authors.affiliation: Department of Anesthesia and Intensive Care, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
authors.forename: Helena
authors.initials: H
authors.lastname: Argiriadou
authors.forename: Kalliopi
authors.initials: K
authors.lastname: Megari
authors.forename: Polychronis
authors.initials: P
authors.lastname: Antonitsis
authors.forename: Mary H
authors.initials: MH
authors.lastname: Kosmidis
authors.forename: Christos
authors.initials: C
authors.lastname: Papakonstantinou
authors.forename: Kyriakos
authors.initials: K
authors.lastname: Anastasiadis
mesh_terms: D003071:Cognition / Q000502:physiology*; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation; D016277:Ventricular Function, Left