title: [Antibiotic resistance and biofilm formation in Staphylococcus saprophyticus strains isolated from urine].
abstract: Eighty-seven Staphylococcus saprophyticus strains isolated from urine of 87 patients with cystitis were examined in 2005-2009. All strains were tested for resistance to vancomycin, nitrofurantoin, doxycycline, oxacillin, amoxicillin/clavulanate, cefoxitin and sulfamethoxazole/trimethoprim and for biofilm formation by a modified Christensen method. None of the tested strains of S. saprophyticus showed resistance to vancomycin, while 2 strains (2.3 %) were resistant to nitrofurantoin, 9 (10.3%) to doxycycline, 20 (23.0 %) to oxacillin, 6 (6.9%) to amoxicillin/clavulanate, 6 (6.9%) to cefoxitin and 1 (1.1%) to sulfamethoxazole/trimethoprim. S. saprophyticus was detected as the causative agent of cystitis in 0.4 % of 20,375 culture positive urine samples analyzed in our laboratory between 2005 and 2009. Most 67 (77.0%) S. saprophyticus strains were recovered from women, particularly from young women. Biofilm formation was detected in 16 (18.4 %) out of 87 S. saprophyticus strains.
authors.affiliation: Mikrobiologický ustav LF MU a FN u sv. Anny v Brne. lenka.cernohorska@fnusa.cz
authors.forename: L
authors.initials: L
authors.lastname: Cernohorská
authors.forename: M
authors.initials: M
authors.lastname: Votava
mesh_terms: D000293:Adolescent; D000328:Adult; D018441:Biofilms / Q000254:growth & development*; D003556:Cystitis / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D013210:Staphylococcus / Q000187:drug effects* / Q000502:physiology; D014556:Urine / Q000382:microbiology*; D055815:Young Adult