title: [Frozen section doesn't reduce the number of reoperations for cancer after hemithyroidectomy].
abstract: FUNDAMENTALS AND OBJECTIVES: Frozen section (FS) constitutes a diagnostic procedure in patients following hemithyroidectomy. It is used to diagnose malignant lesions and to avoid reoperations. Our objective is to confirm this test as useless to rule out cancer.
  
  
  METHODS
  Retrospective and comparative trial between two series of patients following hemithyroidectomy. G I: 179 patients operated in 1995-2002. In this period we performed systematic FS. Sensitivity (S), specificity (E) and predictive values (PPV, NPV) are analyzed. G II: 126 patients were operated between 2003-2008. Selective FS was performed (23 patients). Both groups are compared: hospital stay, number of FS, percentage of cancer, definitive biopsy and reoperations.
  
  
  RESULTS
  Data analyzed in the first period: S: 48%, E: 100%, PPV: 100%, NPV: 90%, positive likelihood ratio>10, negative likelihood ratio 0.52. When both periods are compared no significant differences between reoperations are found.
  
  
  CONCLUSIONS
  FS during hemithyroidectomy does not reduce reoperations for cancer.
authors.affiliation: Servicio de Cirugía General, Hospital General Universitario J.M. Morales Meseguer, Murcia, Spain. be240762@terra.es
authors.forename: Benito
authors.initials: B
authors.lastname: Flores-Pastor
authors.forename: Joana
authors.initials: J
authors.lastname: Miquel Perelló
authors.forename: Mónica
authors.initials: M
authors.lastname: Mengual Ballester
authors.forename: Alvaro
authors.initials: A
authors.lastname: Campillo Soto
authors.forename: Victoriano
authors.initials: V
authors.lastname: Soria Aledo
authors.forename: José Luis
authors.initials: JL
authors.lastname: Aguayo Albasini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008875:Middle Aged; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D055815:Young Adult