Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi.
This study characterized a cephalosporin-resistant Salmonella enterica serovar Typhi isolate. The organism possessed a plasmid encoding the CTX-M-15 extended-spectrum-beta-lactamase. This plasmid is the determinant for the phenotype of cephalosporin resistance and is transferrable among Enterobacteriaceae.
Morita
Masatomo
M
Department of Bacteriology I, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo, 162-8640, Japan.
Takai
Nobuko
N
Terajima
Jun
J
Watanabe
Haruo
H
Kurokawa
Manabu
M
Sagara
Hiroko
H
Ohnishi
Kenji
K
Izumiya
Hidemasa
H
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D012485:Salmonella typhi; D001618:beta-Lactamases / Q000235:genetics
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases