title: Clinicians' use of guidelines as illustrated by curative treatment of prostate cancer at a comprehensive cancer center.
abstract: BACKGROUND
  We studied compliance to guidelines of curative treatments in prostate cancer (PCa), which were of special interest due to recent introduction of new treatment technologies and the fact that there existed a real choice between surgery and radiotherapy.
  
  
  METHODS
  We did retrospective analyses of guidelines adherence for all PCa patients receiving curative treatment at the Norwegian Radium Hospital from 2004 to 2007 after the introduction of robot-assisted prostatectomy and after-loading brachytherapy. The patients were classified into three groups in relation to guidelines: the accordance, accordance after discussion, and the deviance groups. In time Period I (2004-2005) the 2003 EAU guidelines were used and in Period II (2006-2007) in-house guidelines with minor modifications of EAU were applied.
  
  
  RESULTS
  During the observation period 859 patients had curative treatment for PCa, and 83% of the patients were treated according to guidelines. In the deviance group (N=146), 119 men (82%) got prostatectomy instead of radiotherapy. The reasons for deviation in the second period were age >65 years (N=70) and surgery in cases with T3 tumors (N=10), Gleason score >8 (N=13) and combinations (N=26). Deviances from guidelines in the radiotherapy group (N=27) mainly concerned patient selecting this treatment due to expectations of preserving sexuality and/or fertility.
  
  
  CONCLUSIONS
  In spite of acceptable overall compliance to guidelines for curative PCa treatment, the proportion of non-adherence should not been overseen, in particular when new treatment technologies are introduced. Guidelines for PCa need to be monitored regularly, and the compliance to guidelines has to be assessed on a regular basis. Guidelines should avoid too strict criteria, particularly in relation to age.
authors.affiliation: Department of Clinical Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Norway. andreas.stensvold@oslo-universitetssykehus.no
authors.forename: Andreas
authors.initials: A
authors.lastname: Stensvold
authors.forename: Alv A
authors.initials: AA
authors.lastname: Dahl
authors.forename: Sophie D
authors.initials: SD
authors.lastname: Fosså
authors.forename: Karol
authors.initials: K
authors.lastname: Axcrona
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Lilleby
authors.forename: Bjørn
authors.initials: B
authors.lastname: Brennhovd
authors.forename: Sigbjørn
authors.initials: S
authors.lastname: Smeland
mesh_terms: D000328:Adult; D000368:Aged; D001918:Brachytherapy / Q000706:statistics & numerical data; D002173:Cancer Care Facilities / Q000706:statistics & numerical data; D002755:Choice Behavior / Q000502:physiology; D003191:Comprehensive Health Care / Q000706:statistics & numerical data; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010820:Physicians / Q000706:statistics & numerical data*; D011468:Prostatectomy / Q000706:statistics & numerical data; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000628:therapy*; D012189:Retrospective Studies