Isolated conjunctival myeloid sarcoma as a presenting sign of acute leukemia.
Myeloid sarcoma is known as a tumor mass of myeloblasts or immature myeloid cells occurring in an extramedullary site. When ophthalmic areas are involved, it is usually located in the orbits and noted at or after the diagnosis of an underlying leukemia. We report a 38 year-old woman who had isolated conjunctival myeloid sarcoma without any other clinical signs and symptoms. Acute myeloid leukemia (AML) was diagnosed after a thorough examination. The image studies revealed no orbital or subcutaneous involvement. The patient had complete remission of AML after systemic chemotherapy. We reported this case to emphasize the unusual presentation of a conjunctival nodule of uncertain origin, particularly if it is salmon- pink and grows rapidly. The patient should undergo prompt evaluation for underlying hematological disease even if there are no ocular or systemic symptoms.
Lo
Wu-Ping
WP
Department of Ophthalmology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Kuo
Chin-Liang
CL
Kuo
Ming-Tse
MT
Fang
Po-Chiung
PC
D000328:Adult; D003230:Conjunctival Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000473:pathology; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000473:pathology