title: Use of ICDAS combined with quantitative light-induced fluorescence as a caries detection method.
abstract: The purpose of this study was to combine a standardized visually based system, the International Caries Detection and Assessment System (ICDAS), with a sensitive fluorescence-based system, quantitative light-induced fluorescence (QLF), to determine the ability to monitor caries lesion progression. This combination (QLF-I) has the potential to increase the sensitivity of the visual method without compromising specificity. A total of 460 children were enrolled and examined at baseline, 8 months and 12 months by ICDAS and QLF by a single examiner. The examiner repeatability for both methods was comparable, varying between weighted kappa of 0.70 and 0.79. The DMFT score was 6.0 (SD 5.8) at baseline and 6.4 (SD 6.3) at 12 months, and both methods were able to follow the increase in incidence. The QLF-I scored more surfaces at the early ICDAS scores (1 and 2) and score 4. Not all lesions progressed at the same rate, differing by score at baseline and surface type.
authors.affiliation: Department of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis, IN, USA. azandona@iupui.edu
authors.forename: A
authors.initials: A
authors.lastname: Ferreira Zandoná
authors.forename: E
authors.initials: E
authors.lastname: Santiago
authors.forename: G
authors.initials: G
authors.lastname: Eckert
authors.forename: M
authors.initials: M
authors.lastname: Fontana
authors.forename: M
authors.initials: M
authors.lastname: Ando
authors.forename: D T
authors.initials: DT
authors.lastname: Zero
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries / Q000175:diagnosis*; D003732:Dental Caries Activity Tests / Q000379:methods*; D018450:Disease Progression; D005260:Female; D005453:Fluorescence; D006801:Humans; D008027:Light; D008137:Longitudinal Studies; D008297:Male; D015588:Observer Variation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity