Two new amide alkaloids from the flower of Datura metel L.
Two new amide alkaloids were isolated from the alkaloidal fraction of Datura metel L. Their structures were elucidated as (E)-methyl 4-(3-(4-hydroxyphenyl)-N-methylacrylamido) butanoate and 6,7-dimethyl-1-D-ribityl-quinoxaline-2,3(1H,4H)-dione-5'-O-β-D-glucopyranoside on the basis of spectroscopic methods including HRESIMS, 1D and 2D NMR. Tropane alkaloids have for a long time been considered as characteristic ingredients of D. metel. However, the presence of amide alkaloids in D. metel was reported for the first time in this study.
Yang
Bing-You
BY
Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Xia
Yong-Gang
YG
Wang
Qiu-Hong
QH
Dou
De-Qiang
DQ
Kuang
Hai-Xue
HX
D000178:Acrylamides / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry*; D058530:Datura metel / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D015394:Molecular Structure; D011810:Quinoxalines / Q000737:chemistry*
C556842:(E)-methyl 4-(3-(4-hydroxyphenyl)-N-methylacrylamido) butanoate; C556844:6,7-dimethyl-1-D-ribityl-quinoxaline-2,3(1H,4H)-dione-5'-O-beta-D-glucopyranoside; D000178:Acrylamides; D000470:Alkaloids; D002087:Butyrates; D005960:Glucosides; D011810:Quinoxalines