title: Rh catalyzed olefination and vinylation of unactivated acetanilides.
abstract: In the catalyzed oxidative olefination of acetanilides (oxidative-Heck coupling), Rh offers great advantages over more common Pd catalysts. Lower catalyst loadings, large functional group tolerance (in particular to halides), and higher reactivity of electron-neutral olefins (styrenes) are some of the attractive features. Most interestingly, even ethylene reacts to yield the corresponding acetanilido-styrene. Moreover, the Cu(II) oxidant can also be utilized in catalytic amounts with air serving as the terminal oxidant.
authors.affiliation: Organisch-Chemisches Institut der Westfälischen Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
authors.forename: Frederic W
authors.initials: FW
authors.lastname: Patureau
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius
mesh_terms: D000083:Acetanilides / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D007536:Isomerism; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000083:Acetanilides; D000475:Alkenes; D012238:Rhodium; C508827:acetanilide