title: Preparation of organoaluminum reagents from propargylic bromides and aluminum activated by PbCl2 and their regio- and diastereoselective addition to carbonyl derivatives.
abstract: Various propargylic and allenic aluminum reagents have been easily prepared by a direct insertion of aluminum into propargylic bromides in the presence of PbCl(2) (1 mol%). These organoaluminum reagents react with carbonyl compounds to afford the corresponding allenic alcohols or homopropargylic alcohols in good to excellent yields with high regio- and diastereoselectivity.
authors.affiliation: Department Chemie and Biochemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, Haus F, 81377 München, Gemany.
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Guo
authors.forename: Hongjun
authors.initials: H
authors.lastname: Gao
authors.forename: Peter
authors.initials: P
authors.lastname: Mayer
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel