title: [The study of adaptation mechanisms of Yarrowia lipolytica yeast to alkaline conditions by means of proteomics].
abstract: Using proteomic technologies--two-dimensional electrophoresis in denaturing conditions in combination with mass spectroscopy of MALDI-TOF proteins--we demonstrated, for the first time, that the most noticeable alteration of protein composition of a Yarrowia lipolytica cell during adaptation to alkaline conditions was an increase of mitochondrial proteins relatively to proteins of cytoplasm.
authors.forename: M A
authors.initials: MA
authors.lastname: Guseeva
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Epova
authors.forename: L I
authors.initials: LI
authors.lastname: Kovalev
authors.forename: A B
authors.initials: AB
authors.lastname: Shelev
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D003593:Cytoplasm / Q000378:metabolism*; D005656:Fungal Proteins / Q000096:biosynthesis*; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000096:biosynthesis*; D040901:Proteomics; D025062:Yarrowia / Q000254:growth & development / Q000378:metabolism*
chemical_list: D005656:Fungal Proteins; D024101:Mitochondrial Proteins