title: [Morpho-functional compensatory changes of colonic mucosa after long-term exposure to urine in the experiment].
abstract: Using 60 outbred albino male rats, the changes of colonic mucosa were studied after rectal infusion of urine for 1, 3 and 5 months. In response to prolonged exposure to urine, the mucosa was found to undergo gradual atrophic changes, including the reduction of its thickness and crypt depth. Moreover, the number of goblet cells was significantly decreased. Oral correction by weak solution of sodium hydrocarbonate could slow down the progression of atrophic processes in colonic mucosa.
authors.forename: A B
authors.initials: AB
authors.lastname: Stroganov
authors.forename: L V
authors.initials: LV
authors.lastname: Shkalova
authors.forename: V A
authors.initials: VA
authors.lastname: Atduev
authors.forename: N V
authors.initials: NV
authors.lastname: Zhemarina
authors.forename: N N
authors.initials: NN
authors.lastname: Prodanets
authors.forename: O S
authors.initials: OS
authors.lastname: Evdokimova
authors.forename: Ch S
authors.initials: ChS
authors.lastname: Zakirov
authors.forename: I A
authors.initials: IA
authors.lastname: Samsonov
mesh_terms: D000818:Animals; D003106:Colon / Q000473:pathology* / Q000503:physiopathology; D020397:Goblet Cells / Q000473:pathology*; D007413:Intestinal Mucosa / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D051381:Rats; D013997:Time Factors; D014556:Urine