Robust generation of lead compounds for protein-protein interactions by computational and MCR chemistry: p53/Hdm2 antagonists.
Czarna
Anna
A
Max-Planck-Institut für Biochemie, Martinsried, Germany.
Beck
Barbara
B
Srivastava
Stuti
S
Popowicz
Grzegorz M
GM
Wolf
Siglinde
S
Huang
Yijun
Y
Bista
Michal
M
Holak
Tad A
TA
Dömling
Alexander
A
D019295:Computational Biology; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D008958:Models, Molecular; D021381:Protein Transport; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors* / Q000378:metabolism
C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2