Overactive bladder: Is there a link to the metabolic syndrome in men?
It is becoming increasingly clear that a variety of metabolic, cardiovascular, and endocrine factors contribute to male pelvic health. In particular, a growing body of evidence suggests a relationship between lower urinary tract symptoms, benign prostatic hyperplasia, overactive bladder, erectile dysfunction, and the metabolic syndrome. This article explores these relationships, focusing on the role of the autonomic nervous system and hyperinsulinemia, together with their implications for urological practice.
Kirby
Michael G
MG
Faculty of Health & Human Sciences, Centre for Research in Primary & Community Care (CRIPACC), University of Hertfordshire, College Lane, Hatfield, Herts, UK. kirbym@globalnet.co.uk
Wagg
Adrian
A
Cardozo
Linda
L
Chapple
Christopher
C
Castro-Diaz
David
D
de Ridder
Dirk
D
Espuna-Pons
Montserrat
M
Haab
Francois
F
Kelleher
Con
C
Kölbl
Heinz
H
Milsom
Ian
I
Van Kerrebroeck
Philip
P
Vierhout
Mark
M
Salvatore
Stefano
S
Tubaro
Andrea
A
D000818:Animals; D001341:Autonomic Nervous System / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000503:physiopathology; D019317:Evidence-Based Medicine; D006801:Humans; D006946:Hyperinsulinism / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D011470:Prostatic Hyperplasia / Q000453:epidemiology / Q000503:physiopathology; D001743:Urinary Bladder / Q000294:innervation*; D053201:Urinary Bladder, Overactive / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy