One new sesquiterpene from Saussurea laniceps.
One new guaiane-type sesquiterpene (1) was isolated from Saussurea laniceps. The structure of the new compound was elucidated by spectroscopic data analysis. The immunomodulatory activity of compound 1 was evaluated. It was found that compound 1 showed significant inhibition for proliferation of murine T cells in vitro.
Wang
Hong-Bing
HB
Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
Zuo
Jian-Ping
JP
Qin
Guo-Wei
GW
D000818:Animals; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects*; D007155:Immunologic Factors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D030441:Saussurea / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects*
D007155:Immunologic Factors; D010936:Plant Extracts; D012717:Sesquiterpenes; C557534:lanicepomine A