title: Computational fluid dynamics for brain circulation and aneurysm with therapeutic devices.
abstract: We analysed fluid dynamics at brain arteries having multiple inflow and out flow like Willis ring based on clinical imaging modalities. In addition, we analysed fluid dynamics with therapeutic devices like coils and stents to simulate their influences to blood flow. 3D CTA and MRA obtained three-dimensional structures of the brain vessels. The centreline was obtained from the three dimensional structure. Diameter of the blood vessels was measured by 3D CTA/MRA then smooth surfaced blood vessel models were created. For the fluid analysis, we developed a home brew software which can display parameters such as streamline, etc. In addition, our CFD (computational fluid dynamics) software can work in collaboration with a CAD (computer aided design) software which we also developed (VCAD: Volume CAD). So, therapeutic devices such as coils, balloons and stents could be placed in the models and CFD analysis could be performed placing devices in the models. The flow pattern in the complicated vascular structure could be calculated such as Willis ring which has multiple inputs like ICA, VA and multiple outlets like MCA and PCA with communicating arteries. CFD with therapeutic devices could also analysed with our system. CFD including communicating arteries will assist the simulation of parent artery occlusion. CFD with therapeutic devices is helpful not only for simulation for embolization, but will help us to design therapeutic devices under computer simulation.
authors.affiliation: Advance Computing Centre; Computational Biomechanics Unit, Riken (The Institute of Physical and Chemical Research); Wako, Japan - fukasaku@med.nagoya-u.ac.jp - fukasaku@postman.riken.go.jp.
authors.forename: K
authors.initials: K
authors.lastname: Fukasaku
authors.forename: M
authors.initials: M
authors.lastname: Negoro
authors.forename: H
authors.initials: H
authors.lastname: Iwase
authors.forename: K
authors.initials: K
authors.lastname: Yokoi
authors.forename: R
authors.initials: R
authors.lastname: Himeno