title: Acute onset lactobacillus endophthalmitis after trabeculectomy: a case report.
abstract: BACKGROUND
  We report a case of early lactobacillus endophthalmitis which occurred ten days after trabeculectomy.
  
  
  METHODS
  A 76-year-old Caucasian diabetic woman underwent uncomplicated trabeculectomy with a collagen implant as an adjunct, in her left phakic eye, for the treatment of uncontrolled open-angle glaucoma. Ten days post-operatively, our patient complained of left phakic eye discharge pain and visual acuity decreased to "light-perception". The anterior chamber had 3+ cells and flare, and there was also 2 mm layered hypopyon. Vitreous involvement was present obscuring visualization of the fundus. On the same day our patient underwent vitrectomy surgery and intra-vitreal and systemic antibiotics were administered. Vitreous cultures grew Lactobacillus brevis. Our patient responded well to treatment and 30 days after vitrectomy visual acuity improved to 1/10. Six months later our patient underwent cataract surgery. Eight months after initial surgery visual acuity was 2/10 and intra-ocular pressure was 14 mmHg without any anti-glaucoma medication.
  
  
  CONCLUSIONS
  This is the first report of acute lactobacillus endophthalmitis in the phakic eye of a diabetic patient after trabeculectomy. Glaucoma surgeons should be aware of the potential for acute post-operative endophthalmitis due to rare microorganisms, such as lactobacillus, in glaucoma filtration surgery, especially in diabetic patients. The literature shows an increased risk of endophthalmitis when anti-metabolites are used in conjunction with trabeculectomy. Perhaps, any type of wound healing modulation, such as collagen or mitomycin-C may increase this risk. However, it is unclear at this time and more studies need to be done. In this single case, vitrectomy combined with intra-vitreal and systemic antibiotics were efficient in limiting the devastating sequels of this complication.
authors.affiliation: Department of Ophthalmology, "G, Gennimatas" Hospital, University of Athens, Greece. igeorgalas@yahoo.com.
authors.forename: Dimitris
authors.initials: D
authors.lastname: Papaconstantinou
authors.forename: Ilias
authors.initials: I
authors.lastname: Georgalas
authors.forename: Themis
authors.initials: T
authors.lastname: Karmiris
authors.forename: Ioannis
authors.initials: I
authors.lastname: Ladas
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Droutsas
authors.forename: Gerasimos
authors.initials: G
authors.lastname: Georgopoulos