Effects of age and concentrate feeding on the expression of MCT 1 and CD147 in the gastrointestinal tract of goats and Hereford finishing beef bulls.
Monocarboxylate transporter 1 (MCT 1) necessary for the absorption of short chain fatty acids in the gastrointestinal tract, was measured in ventral wall of rumen, abomasum and duodenum of kids at age of 1 day and 1, 2 and 8 weeks. Samples from rumen, abomasum and duodenum were also taken from finishing beef bulls fed concentrate either ad libitum (A) or restrictively (R). Increased expression of MCT 1 was observed during the first week and parallel increases were found in its ancillary protein, CD147 in the rumen of kids. In duodenum, MCT 1 decreased with age and a similar tendency was seen in abomasum. In bulls, MCT 1 was higher in ventral wall and atrium than in other parts of gastrointestinal tract. However, in ventral wall of rumen MCT 1 was higher in A than in R. These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.
Koho
N M
NM
Divisions of Veterinary Biosciences and Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Taponen
J
J
Tiihonen
H
H
Manninen
M
M
Pösö
A R
AR
D000375:Aging; D000821:Animal Feed; D000818:Animals; D051926:Basigin / Q000235:genetics / Q000378:metabolism*; D002417:Cattle / Q000254:growth & development / Q000378:metabolism*; D004032:Diet / Q000662:veterinary; D041981:Gastrointestinal Tract / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000502:physiology; D006041:Goats / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D027501:Monocarboxylic Acid Transporters / Q000235:genetics / Q000378:metabolism*; D027981:Symporters / Q000235:genetics / Q000378:metabolism*; D000099233:Monocarboxylate Transport Protein 1
D051926:Basigin; D027501:Monocarboxylic Acid Transporters; D027981:Symporters; D000099233:Monocarboxylate Transport Protein 1