Minimal hepatic encephalopathy: consensus statement of a working party of the Indian National Association for Study of the Liver.
Hepatic encephalopathy (HE) is a major complication that develops in some form and at some stage in a majority of patients with liver cirrhosis. Overt HE occurs in approximately 30-45% of cirrhotic patients. Minimal HE (MHE), the mildest form of HE, is characterized by subtle motor and cognitive deficits and impairs health-related quality of life. The Indian National Association for Study of the Liver (INASL) set up a Working Party on MHE in 2008 with a mandate to develop consensus guidelines on various aspects of MHE relevant to clinical practice. Questions related to the definition of MHE, its prevalence, diagnosis, clinical characteristics, pathogenesis, natural history and treatment were addressed by the members of the Working Party.
Dhiman
Radha K
RK
Department of Hepatology, Postgraduate Institute of Medical Education & Research, Chandigarh, India. rkpsdhiman@hotmail.com
Saraswat
Vivek A
VA
Sharma
Barjesh K
BK
Sarin
Shiv K
SK
Chawla
Yogesh K
YK
Butterworth
Roger
R
Duseja
Ajay
A
Aggarwal
Rakesh
R
Amarapurkar
Deepak
D
Sharma
Praveen
P
Madan
Kaushal
K
Shah
Samir
S
Seth
Avnish K
AK
Gupta
Rakesh K
RK
Koshy
Abraham
A
Rai
Ramesh R
RR
Dilawari
Jang B
JB
Mishra
Sri Prakash
SP
Acharya
Subrat K
SK
D000465:Algorithms; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003245:Consensus Statements as Topic; D018450:Disease Progression; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006501:Hepatic Encephalopathy / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D017410:Practice Guidelines as Topic; D015995:Prevalence; D019936:Probiotics / Q000627:therapeutic use*; D011788:Quality of Life; D012955:Societies, Medical; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D005765:Gastrointestinal Agents