title: Novel treatment for chylothorax after esophagectomy with 50% glucose pleurodesis.
abstract: Chylothorax is characterized by the presence of chyle in the pleural space and cardiothoracic surgery accounts for nearly half of all the cases. Treatment of chylothorax has traditionally been nonoperative, with alternative medical therapies involving the administration of octreotide or pleurodesis. Pleurodesis with chemical agents has previously been reported, but never with 50% glucose and 0.1% xylocaine. Herein, we report a successful method of intrapleural instillation of 50% glucose and 0.1% xylocaine to treat chylothorax. Five patients treated with this method were all recovered rapidly. This method can generate extensive adherence and prevent the effusion of the chylous fluid with minor side effects.
authors.affiliation: Department of Lung Cancer, Cancer Institute & Hospital, Tian Jin Medical University, Tian Jin, PR China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Chen
authors.forename: Changyuan
authors.initials: C
authors.lastname: Li
authors.forename: Lijun
authors.initials: L
authors.lastname: Xu
authors.forename: Hongjing
authors.initials: H
authors.lastname: Lin
authors.forename: Youbin
authors.initials: Y
authors.lastname: Cui
authors.forename: Jean
authors.initials: J
authors.lastname: Deslauriers
mesh_terms: D000328:Adult; D000368:Aged; D002916:Chylothorax / Q000209:etiology / Q000628:therapy*; D004322:Drainage; D016629:Esophagectomy / Q000009:adverse effects*; D005260:Female; D005950:Glucose Solution, Hypertonic / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010289:Parenteral Nutrition, Total; D018700:Pleurodesis / Q000009:adverse effects / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D005950:Glucose Solution, Hypertonic; D008012:Lidocaine