Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature.
Cancer metastasis to the thyroid is extremely rare. The more commonly reported primary sites for metastasis to the thyroid are the kidney, breast, lung, colon, esophagus, and uterus. Thyroid metastasis from the stomach has only been reported in three cases. Herein, we report a 71-year-old man presenting with bilateral thyroid multinodular lesions. Bilateral near-total thyroidectomy was performed due to airway compression with related symptoms. Wedge resection of a suspicious pulmonary nodule, detected on CT, was performed for diagnosis. Polypoid lesions in the stomach were examined by trans-scopic biopsy. Poorly differentiated adenocarcinomas with the same histological profiles were noted at these three sites. The immunohistochemical staining for thyroglobulin of these specimens was negative. We conclude that a new thyroid mass appearing in a patient with present or prior malignancies should raise the concern of metastatic disease.
Lee
Hwa-chan
HC
Department of Surgery, St. Martin de Porres Hospital, Chia-Yi City, Taiwan, China.
Chen
Fen-fen
FF
Lo
Ching-chu
CC
Wang
Chung-jing
CJ
Lo
Wei-chun
WC
Luh
Shi-ping
SP
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male; D013274:Stomach Neoplasms / Q000175:diagnosis; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000556:secondary*