Visceral Leishmaniasis treated with antimonials/paromomycin followed by itraconazole/miltefosine after standard therapy failures in a human immunodeficiency virus-infected patient.
Visceral leishmaniasis is an opportunistic infection that affects human immunodeficiency virus-infected persons in leishmaniasis-endemic areas. The standard treatment may not be effective and relapses are common. We report the case of a human immunodeficiency virus-1-infected patient who had several relapses of visceral leishmaniasis after treatment with standard therapies and responded to a combined therapy.
Barragán
Patricia
P
Infectious Disease Service, Hospital Universitari de Bellvitge, L'Hospitalet, Barcelona, Spain. pbarragan@bellvitgehospital.cat
López-Velez
Rogelio
R
Olmo
Montserrat
M
Podzamczer
Daniel
D
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000209:etiology; D006678:HIV; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D015497:HIV-1; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D007896:Leishmaniasis; D016773:Leishmaniasis, Cutaneous; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000503:physiopathology*; D009894:Opportunistic Infections / Q000150:complications; D021261:Parasitic Sensitivity Tests; D010303:Paromomycin / Q000627:therapeutic use*; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012008:Recurrence; D017211:Treatment Failure
D010767:Phosphorylcholine; D017964:Itraconazole; C039128:miltefosine; D010303:Paromomycin