RECIST versus volume measurement in medical CT using ellipsoids of known size.
Two hundred eighty three uniaxial ellipsoids with sizes from 4 mm to 11 mm were measured with a coordinate measuring matching (CMM) and also scanned using a medical computed tomography (CT) machine. Their volumes were determined by counting voxels over a threshold, as well as using equivalent volumes from the length given by the RECIST 1.1 criterion (Response Evaluation Criteria in Solid Tumors). The volumetric measurements yield an order of magnitude reduction in residuals compared to the CMM measurements than the residuals of the RECIST measurements also compared to the CMM measurements.
Levine
Zachary H
ZH
National Institute for Standards and Technology, 100 Bureau Drive, Gaithersburg, Maryland 20899, USA. zlevine@nist.gov
Borchardt
Bruce R
BR
Brandenburg
Nolan J
NJ
Clark
Charles W
CW
Muralikrishnan
Bala
B
Shakarji
Craig M
CM
Chen
Joseph J
JJ
Siegel
Eliot L
EL
D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods*