Targeting microglial purinergic signaling to improve morphine analgesia.
Ji
Ru-Rong
RR
Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
D000818:Animals; D039481:CD11b Antigen / Q000378:metabolism; D006801:Humans; D051379:Mice; D017628:Microglia / Q000187:drug effects* / Q000378:metabolism; D009020:Morphine / Q000494:pharmacology* / Q000627:therapeutic use; D009294:Narcotics / Q000494:pharmacology* / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy / Q000378:metabolism; D058848:Receptors, Purinergic P2X4 / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D013116:Spinal Cord / Q000473:pathology
D039481:CD11b Antigen; D009294:Narcotics; D058848:Receptors, Purinergic P2X4; D009020:Morphine