title: Fungal pathogenicity and morphological switches.
abstract: The virulence of Candida albicans, a major human fungal pathogen, has been considered dependent on the ability to transition between different morphologies. A new study reports a screen of C. albicans mutants that demonstrates that pathogenesis can be dissociated from morphological switching and in vitro growth rate.
authors.forename: P T
authors.initials: PT
authors.lastname: Magee
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000235:genetics* / Q000254:growth & development / Q000472:pathogenicity; D002177:Candidiasis / Q000382:microbiology*; D004195:Disease Models, Animal; D005260:Female; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D017353:Gene Deletion; D005963:Glucosylceramides / Q000096:biosynthesis; D006801:Humans; D025301:Hyphae / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D051379:Mice; D009024:Morphogenesis; D009154:Mutation; D014774:Virulence / Q000235:genetics
chemical_list: D005656:Fungal Proteins; D005963:Glucosylceramides