title: Two new amide alkaloids from the flower of Datura metel L.
abstract: Two new amide alkaloids were isolated from the alkaloidal fraction of Datura metel L. Their structures were elucidated as (E)-methyl 4-(3-(4-hydroxyphenyl)-N-methylacrylamido) butanoate and 6,7-dimethyl-1-D-ribityl-quinoxaline-2,3(1H,4H)-dione-5'-O-β-D-glucopyranoside on the basis of spectroscopic methods including HRESIMS, 1D and 2D NMR. Tropane alkaloids have for a long time been considered as characteristic ingredients of D. metel. However, the presence of amide alkaloids in D. metel was reported for the first time in this study.
authors.affiliation: Heilongjiang University of Chinese Medicine, Harbin 150040, China.
authors.forename: Bing-You
authors.initials: BY
authors.lastname: Yang
authors.forename: Yong-Gang
authors.initials: YG
authors.lastname: Xia
authors.forename: Qiu-Hong
authors.initials: QH
authors.lastname: Wang
authors.forename: De-Qiang
authors.initials: DQ
authors.lastname: Dou
authors.forename: Hai-Xue
authors.initials: HX
authors.lastname: Kuang
mesh_terms: D000178:Acrylamides / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry*; D058530:Datura metel / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D015394:Molecular Structure; D011810:Quinoxalines / Q000737:chemistry*
chemical_list: C556842:(E)-methyl 4-(3-(4-hydroxyphenyl)-N-methylacrylamido) butanoate; C556844:6,7-dimethyl-1-D-ribityl-quinoxaline-2,3(1H,4H)-dione-5'-O-beta-D-glucopyranoside; D000178:Acrylamides; D000470:Alkaloids; D002087:Butyrates; D005960:Glucosides; D011810:Quinoxalines