title: Novel heteronuclear ruthenium-copper coordination compounds as efficient DNA-cleaving agents.
abstract: The DNA-cleavage ability of novel bifunctional heterobimetallic copper-ruthenium complexes is demonstrated by using gel electrophoresis.
authors.affiliation: Gorlaeus Laboratories, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.
authors.forename: Stefanie
authors.initials: S
authors.lastname: van der Steen
authors.forename: Paul
authors.initials: P
authors.lastname: de Hoog
authors.forename: Karlijn
authors.initials: K
authors.lastname: van der Schilden
authors.forename: Patrick
authors.initials: P
authors.lastname: Gamez
authors.forename: Marguerite
authors.initials: M
authors.lastname: Pitié
authors.forename: Robert
authors.initials: R
authors.lastname: Kiss
authors.forename: Jan
authors.initials: J
authors.lastname: Reedijk
mesh_terms: D003300:Copper / Q000737:chemistry*; D004247:DNA / Q000187:drug effects*; D053837:DNA Cleavage; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D003300:Copper; D012428:Ruthenium; D004247:DNA