title: Calcification of a Rayner Centerflex 570H hydrophilic acrylic intraocular lens following vitrectomy for retinal detachment: a clinicopathologic report.
abstract: OBJECTIVE
  The case of a 71-year-old man who complained of progressive, unilateral visual blurring following vitrectomy for retinal detachment due to opacification of his Rayner Centerflex 570H intraocular lens (IOL) implant is reported. Intraocular lens exchange was carried out and the explanted lens analyzed. The same model lens in his fellow eye has remained clear.
  
  
  METHODS
  Clinicopathologic case report.
  
  
  RESULTS
  Scanning electron microscopy and energy-dispersive x-ray analysis confirmed the presence of hydroxyapatite deposits within the anterior surface of the IOL.
  
  
  CONCLUSIONS
  To our knowledge, this is the first clinicopathologic case report of calcification of this model IOL in an adult patient. The sequence of events, unilaterality, and pathologic findings suggest secondary calcification, which could have been related to severe postoperative inflammation and associated blood-aqueous barrier breakdown.
authors.affiliation: Oxford Eye Hospital, John Radcliffe Hospital, Headley Way, Headington,Oxford, UK.
authors.forename: Robert M J
authors.initials: RM
authors.lastname: Purbrick
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Stavrakas
authors.forename: Hamid
authors.initials: H
authors.lastname: Porooshani
authors.forename: Chetan K
authors.initials: CK
authors.lastname: Patel
authors.forename: David J P
authors.initials: DJ
authors.lastname: Ferguson
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D002114:Calcinosis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008855:Microscopy, Electron, Scanning; D018918:Phacoemulsification; D011475:Prosthesis Failure; D012163:Retinal Detachment / Q000601:surgery*; D013052:Spectrometry, X-Ray Emission; D014786:Vision Disorders / Q000209:etiology; D014821:Vitrectomy
chemical_list: D000180:Acrylic Resins