title: [Comparison of flavonoids content in huangqi gnizhi wuwu tang of different dosages by uniform design method].
abstract: OBJECTIVE
  To determine the content of flavonoids in huangqi guizhi wuwu tang (HQGZWWT) of different dosages by uniform design method and analyze their difference for clinical application.
  
  
  METHODS
  The uniform design set five factors and 11 levels to explore the content of flavonoids. The results were analyzed by computer with the method of multiple regression analysis.
  
  
  RESULTS
  The contribution of each medicinal material to the content of total flavonoids was Radix Astragali (51.8%), Rhizoma Zingiberis (0.967%), Rhizoma Zingiberis (0.689%), Ramulus Cinnamomi (0.381%) and Raidix Paenoiae alba (0.185%), respectively.
  
  
  CONCLUSIONS
  The extraction rate of flavonoids is not directly relative to the total amount of medicines, instead, there is an optimum dosage matching for it.
authors.forename: Hong-rong
authors.initials: HR
authors.lastname: Bian
authors.forename: Gui-qin
authors.initials: GQ
authors.lastname: Lou
authors.forename: Qing-bo
authors.initials: QB
authors.lastname: Zhang
authors.forename: Zi-jia
authors.initials: ZJ
authors.lastname: Zhao
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
mesh_terms: D027883:Astragalus Plant / Q000737:chemistry*; D027424:Cinnamomum / Q000737:chemistry*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis*; D029596:Paeonia / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012044:Regression Analysis; D013056:Spectrophotometry, Ultraviolet; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005419:Flavonoids