Surface biocompatible modification of polypropylene by entrapment of polypropylene-block-poly(vinylpyrrolidone).
A macromolecular surface modifier, namely polypropylene-block-poly(vinylpyrrolidone) copolymer, could diffuse preferably onto the surface and effectively increased the biocompatibility of PP. The blood and cell compatibilities of PP and PP-b-PVP/PP blend films were evaluated by determination of the extent of platelet adsorption, plasma recalcification time, hemolysis rate and cell proliferation using smooth muscle cells from rabbit aorta. The results revealed that the blood and cell compatibilities of PP were improved significantly by entrapment of a few PP-b-PVP copolymers in PP.
Xu
Man
M
School of Science, Shantou University, Shantou 515063, China.
Qiu
Jingfeng
J
Lin
Yuemei
Y
Shi
Xuhua
X
Chen
Hanjia
H
Xiao
Tan
T
D000818:Animals; D001011:Aorta / Q000166:cytology; D001672:Biocompatible Materials / Q000009:adverse effects* / Q000138:chemical synthesis / Q000737:chemistry*; D049109:Cell Proliferation / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D032389:Myocytes, Smooth Muscle / Q000166:cytology / Q000187:drug effects; D011108:Polymers / Q000009:adverse effects* / Q000138:chemical synthesis / Q000737:chemistry*; D011126:Polypropylenes / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry*; D011817:Rabbits; D013499:Surface Properties
D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D011126:Polypropylenes; D011759:Pyrrolidines