title: Acute hepatitis and personality change in a 31-year-old man taking prohormone supplement SUS500.
abstract: BACKGROUND
  For decades, anabolic-androgenic steroids have been abused to enhance muscle growth. The harm inflicted by these compounds is well documented.
  
  
  OBJECTIVE
  The authors investigated and report on a case in which a male patient self-prescribed some newer dietary supplements, about which less is known.
  
  
  METHODS
  The authors report on a case of hepatitis and aggressive personality changes in a 31-year-old man taking purported prohormone agent SUS500 and other, newer supplements.
  
  
  RESULTS
  Diagnosis was based on history, mental status exam, and laboratory findings. With discontinuation of all supplements and supportive care, the patient's personality changes resolved, and normal liver function returned.
  
  
  CONCLUSIONS
  The authors conclude that newer anabolic supplements may cause some of the same side effects as traditional steroid hormones.
authors.affiliation: Dept. of Psychiatry, Naval Medical Center, Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA.
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Wingert
authors.forename: Hamid
authors.initials: H
authors.lastname: Tavakoli
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Yoder
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage; D000208:Acute Disease; D000328:Adult; D000374:Aggression / Q000187:drug effects; D045930:Anabolic Agents / Q000506:poisoning*; D000728:Androgens / Q000506:poisoning*; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D019587:Dietary Supplements; D004300:Doping in Sports / Q000379:methods / Q000523:psychology; D005221:Fatigue / Q000150:complications; D005492:Folic Acid / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects; D008297:Male; D018908:Muscle Weakness / Q000150:complications; D010551:Personality / Q000187:drug effects*; D010554:Personality Disorders / Q000139:chemically induced* / Q000628:therapy; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced / Q000150:complications; D013256:Steroids / Q000009:adverse effects; D013831:Thiamine / Q000008:administration & dosage; D014891:Weight Lifting
chemical_list: D045930:Anabolic Agents; D000728:Androgens; D013256:Steroids; D005492:Folic Acid; D000111:Acetylcysteine; D013831:Thiamine