title: A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications.
abstract: A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.
authors.affiliation: Department of Chemistry, School of Science, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Baocun
authors.initials: B
authors.lastname: Zhu
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Zhang
authors.forename: Yamin
authors.initials: Y
authors.lastname: Li
authors.forename: Pengfei
authors.initials: P
authors.lastname: Wang
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Zhuang
mesh_terms: D003124:Colorimetry; D005456:Fluorescent Dyes / Q000737:chemistry*; D005978:Glutathione / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D053644:Naphthalimides / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D053644:Naphthalimides; D013438:Sulfhydryl Compounds; D005978:Glutathione