title: [38 year-old patient with suspected congenital hormonal dysfunction].
abstract: We present the case of a patient with suspected congenital hypopituitarism first diagnosed at the age of 38 years. Despite partial insufficiency of all pituitary-regulated hormonal axes, the patient never suffered from severe health problems. However, the patient was disfigured, and his intellectual and physical capacities were clearly impaired. The initiation of a hormone replacement therapy with hydrocortisone and thyroid hormones is essential in such a patient, but the substitution of sex hormones can create ethical problems.
authors.affiliation: Schwerpunkt Endokrinologie und Stoffwechsel, Medizinische Klinik 1, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland. tanja.bergmann@uk-erlangen.de
authors.forename: T
authors.initials: T
authors.lastname: Bergmann
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
authors.forename: P
authors.initials: P
authors.lastname: Lohse
authors.forename: I A
authors.initials: IA
authors.lastname: Harsch
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004992:Ethics, Medical; D020249:Hormone Replacement Therapy / Q000941:ethics; D019382:Human Growth Hormone / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007006:Hypogonadism / Q000151:congenital / Q000175:diagnosis / Q000188:drug therapy; D007018:Hypopituitarism / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D010024:Osteoporosis / Q000151:congenital / Q000175:diagnosis / Q000188:drug therapy; D010901:Pituitary Function Tests; D013739:Testosterone / Q000627:therapeutic use; D013963:Thyroid Hormones / Q000627:therapeutic use
chemical_list: D013963:Thyroid Hormones; D019382:Human Growth Hormone; D013739:Testosterone; D006854:Hydrocortisone