Genetic analysis of a hantavirus strain carried by Niviventer confucianus in Yunnan province, China.
Hantavirus genome sequences were recovered from lung tissues of Chinese white-bellied rats (Niviventer confucianus) captured in Yunnan province, China. Pairwise comparison of the nucleotide and deduced amino acid sequences of the entire S and partial M and L segments indicated that the newly discovered virus strain, which was designated as strain YN509, was very different from other rodent-borne hantaviruses. Phylogenetic analysis showed that the new strain fit into a clade containing Da Bie Shan virus (DBSV) (also carried by N. confucianus), which is mainly found in Anhui Province in mainland China. Strain YN509 appears to be in a sister taxa of the DBSV group described previously. These data suggest that strain YN509 is a new subtype of DBSV, which appears to be widely distributed in China with a higher genetic diversity than expected.
Cao
Zhi-Wei
ZW
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20-Dongda Street, Fengtai District, Beijing 100071, China.
Zuo
Shu-Qing
SQ
Gong
Zheng-Da
ZD
Zhan
Lin
L
Bian
Chang-Ling
CL
Zhang
Pan-He
PH
Yang
Hong
H
Zhang
Jiu-Song
JS
Zhao
Qiu-Min
QM
Jia
Na
N
Cao
Wu-Chun
WC
D000818:Animals; D002681:China; D016000:Cluster Analysis; D006476:Orthohantavirus / Q000235:genetics* / Q000302:isolation & purification; D018778:Hantavirus Infections / Q000662:veterinary* / Q000821:virology; D008168:Lung / Q000821:virology; D008969:Molecular Sequence Data; D051189:Murinae / Q000821:virology*; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D051381:Rats; D012376:Rodent Diseases / Q000821:virology*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000235:genetics
D012367:RNA, Viral; D014764:Viral Proteins