The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics.
Luzzatto
Lucio
L
Istituto Toscano Tumori, Florence, Italy. lucio.luzzatto@ittumori.it
D000743:Anemia, Hemolytic / Q000139:chemically induced / Q000209:etiology*; D000962:Antimalarials / Q000009:adverse effects* / Q000627:therapeutic use; D003622:Dapsone / Q000009:adverse effects* / Q000627:therapeutic use; D004338:Drug Combinations; D004351:Drug Resistance; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D010597:Pharmacogenetics; D002727:Proguanil / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000962:Antimalarials; D004338:Drug Combinations; C519882:chloroguanil, dapsone drug combination; D003622:Dapsone; D002727:Proguanil