title: A simple low-SAR technique for chemical-shift selection with high-field spin-echo imaging.
abstract: We have discovered a simple and highly robust method for removal of chemical shift artifact in spin-echo MR images, which simultaneously decreases the radiofrequency power deposition (specific absorption rate). The method is demonstrated in spin-echo echo-planar imaging brain images acquired at 7 T, with complete suppression of scalp fat signal. When excitation and refocusing pulses are sufficiently different in duration, and thus also different in the amplitude of their slice-select gradients, a spatial mismatch is produced between the fat slices excited and refocused, with no overlap. Because no additional radiofrequency pulse is used to suppress fat, the specific absorption rate is significantly reduced compared with conventional approaches. This enables greater volume coverage per unit time, well suited for functional and diffusion studies using spin-echo echo-planar imaging. Moreover, the method can be generally applied to any sequence involving slice-selective excitation and at least one slice-selective refocusing pulse at high magnetic field strengths. The method is more efficient than gradient reversal methods and more robust against inhomogeneities of the static (polarizing) field (B(0)).
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. divanov@cbs.mpg.de
authors.forename: Dimo
authors.initials: D
authors.lastname: Ivanov
authors.forename: Andreas
authors.initials: A
authors.lastname: Schäfer
authors.forename: Markus N
authors.initials: MN
authors.lastname: Streicher
authors.forename: Robin M
authors.initials: RM
authors.lastname: Heidemann
authors.forename: Robert
authors.initials: R
authors.lastname: Trampel
authors.forename: Robert
authors.initials: R
authors.lastname: Turner
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology*; D001923:Brain Chemistry; D017352:Echo-Planar Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013113:Spin Labels
chemical_list: D013113:Spin Labels