title: Postexposure treatment of Marburg virus infection.
abstract: Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.
authors.affiliation: National Emerging Infectious Diseases Laboratories Institute, Boston, Massachusetts 02118, USA. geisbert@bu.edu
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Geisbert
authors.forename: Lisa E
authors.initials: LE
authors.lastname: Hensley
authors.forename: Joan B
authors.initials: JB
authors.lastname: Geisbert
authors.forename: Anders
authors.initials: A
authors.lastname: Leung
authors.forename: Joshua C
authors.initials: JC
authors.lastname: Johnson
authors.forename: Allen
authors.initials: A
authors.lastname: Grolla
authors.forename: Heinz
authors.initials: H
authors.lastname: Feldmann
mesh_terms: D000818:Animals; D008253:Macaca mulatta; D008379:Marburg Virus Disease / Q000517:prevention & control*; D029024:Marburgvirus / Q000276:immunology*; D008992:Monkey Diseases / Q000517:prevention & control*; D014614:Vaccines, Synthetic / Q000276:immunology; D014721:Vesicular stomatitis Indiana virus / Q000235:genetics; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D014614:Vaccines, Synthetic; D014765:Viral Vaccines