title: Design and investigation of a series of rhodamine-based fluorescent probes for optical measurements of pH.
abstract: A series of structurally similar fluorescent probes (1-4), synthesized from rhodamine B, were designed to optically measure pH. Each probe had a unique "off-on" response as the solution went from basic to acidic. Probes 1-3 exhibited a spirocyclic quenching of the pyronin B fluorophore, whereas probe 4 was quenched by PET from the amine moiety.
authors.affiliation: Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois 62901, USA.
authors.forename: Quinn A
authors.initials: QA
authors.lastname: Best
authors.forename: Ruisong
authors.initials: R
authors.lastname: Xu
authors.forename: Matthew E
authors.initials: ME
authors.lastname: McCarroll
authors.forename: Lichang
authors.initials: L
authors.lastname: Wang
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Dyer
mesh_terms: D015195:Drug Design; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D055620:Optical Phenomena; D012235:Rhodamines / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines