title: Senior-Loken syndrome in an Iranian family.
abstract: Senior-Loken syndrome is a rare entity that combines familial juvenile nephronophthisis with retinal dystrophy. Herein, we report Senior-Loken syndrome in six members of an Iranian family with progressive blindness and renal failure since childhood. Although, this syndrome was reported from other parts of the world, report of six members of one family with this syndrome is rare. To the best of our knowledge, this is the first report from Iran.
authors.affiliation: Urology Nephrology Research Center, Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Jamshid
authors.initials: J
authors.lastname: Roozbeh
authors.forename: Maryam
authors.initials: M
authors.lastname: Sharifian
authors.forename: Hamid
authors.initials: H
authors.lastname: Hosseini
authors.forename: Mohammad Mahdi
authors.initials: MM
authors.lastname: Sagheb
authors.forename: Saeed
authors.initials: S
authors.lastname: Behzadi
authors.forename: Ghanbar Ali
authors.initials: GA
authors.lastname: Raeisjalali
authors.forename: Alireza
authors.initials: A
authors.lastname: Iraniparast
authors.forename: Raha
authors.initials: R
authors.lastname: Afshariani
authors.forename: Masume
authors.initials: M
authors.lastname: Tohidi
authors.forename: Mostafa
authors.initials: M
authors.lastname: Sharifian
mesh_terms: D000293:Adolescent; D000328:Adult; D001766:Blindness; D002386:Cataract / Q000175:diagnosis; D002387:Cataract Extraction; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D007674:Kidney Diseases / Q000150:complications / Q000235:genetics*; D008297:Male; D009679:Nuclear Family; D012162:Retinal Degeneration / Q000150:complications / Q000235:genetics*; D012174:Retinitis Pigmentosa / Q000175:diagnosis; D035781:Siblings; D013577:Syndrome