title: Wear pattern observations from TDR retrievals using autoregistration of voxel data.
abstract: Because of their unique geometry, characterization of wear damage in total disc replacement (TDR) is difficult. In the article, we developed and validated an automated damage calculation technique for explanted TDR components. Eight polyethylene cores implanted from 4.6 to 16.0 years were using cone-beam microCT imaging (SCANCO Medical, Switzerland). The nominal uniform voxel size for the implant under investigation was 18 mum, however with a smaller sample size increased resolutions (10-microm nominal voxel size) could be achieved using the same microCT imaging hardware. Nominal surface data for both sizes of TDR components we examined were obtained from manufacturer's drawings (Link, Germany) and converted to highly discretized triangular meshes. The damage calculation technique utilized an initial alignment phase, followed by a pointwise calculation of the linear damage at each 3D surface point. During the alignment phase, a three-dimensional surface of the undamaged component was automatically aligned with volumetric image data from the damaged component. The alignment algorithm maximized the contact area between undamaged portions of the implant and its nominal surface using an iterative optimization technique. Linear damage at each triangle on the nominal surface was computed by moving along the local normal of the surface both inward and outward direction for a distance much less than the size of the implant. For the retrieved components, the maximum damage occurred away from the central axis of the dome close to the rim. Penetrations of up to 0.8 mm were observed in this region. Lower magnitude penetrations were observed near the pole of the dome. In conclusion, we have developed an analytical method to automatically align and measure three-dimensional surface damage with both high resolution and accuracy on implants with complicated, nonparametric, surface geometry and used this technique to analyze eight implants.
authors.affiliation: Exponent, Inc., 3401 Market St., Suite 300, Philadelphia, Pennsylvania 19104.|School of Biomedical Engineering, Science, and Heath Systems, Drexel University, Philadelphia, Pennsylvania 19104.
authors.forename: Yakov P
authors.initials: YP
authors.lastname: Shkolnikov
authors.affiliation: Department of Mechanical Engineering, Brigham Young University, Provo, Utah 84602.
authors.forename: Anton
authors.initials: A
authors.lastname: Bowden
authors.affiliation: Implant Research Center, School of Biomedical Engineering, Science, and Heath Systems and Drexel University, Philadelphia, Pennsylvania 19104.
authors.forename: Daniel
authors.initials: D
authors.lastname: MacDonald
authors.affiliation: Exponent, Inc., 3401 Market St., Suite 300, Philadelphia, Pennsylvania 19104.|Implant Research Center, School of Biomedical Engineering, Science, and Heath Systems and Drexel University, Philadelphia, Pennsylvania 19104.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Kurtz
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery*; D008297:Male; D008422:Materials Testing / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D020959:Polyethylene; D019736:Prostheses and Implants / Q000592:standards*; D011475:Prosthesis Failure; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*
chemical_list: D020959:Polyethylene