Shigella-associated diarrhea in children in South Jakarta, Indonesia.
A surveillance of Shigella infections was conducted on 612 children aged 0-12 years-old presenting with diarrhea to Mampang and Tebet Community Health Centers in South Jakarta, Indonesia, during February 2005 through September 2007. Shigella was isolated from 9.3% of diarrhea patients in the health centers. S.flexneri which was found in 5.9% of patients, and was the most frequent species isolated, comprising 63.2% (36/57) of all Shigella species isolated. Shigella species were found significantly more often among children over 2 years old, and the rate of isolation increased with age. Stool with mucus and/or blood were the main characteristics of Shigella infection in these patients. Antibiotic multi-resistance was found in S. flexneri and S. boydii strains, in particular to ampicillin, chloramphenicol, tetracycline, and trimethoprim-sulfamethoxazole. None of the Shigella species showed resistance to nalidixic acid, norfloxacin, ciprofloxacin, or ceftriaxone
Herwana
Elly
E
Department of Medical Pharmacology, Medical Faculty, Trisakti University, Jakarta, Indonesia. elly_herwana@cbn.net.id
Surjawidjaja
Julius E
JE
Salim
Oktavianus Ch
OCh
Indriani
Novia
N
Bukitwetan
Paul
P
Lesmana
Murad
M
D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D012760:Shigella / Q000302:isolation & purification*