Optimizing surgical care: a contemporary assessment of temperature, oxygen, and glucose.
Factors such as temperature, oxygen, and glucose have recently been implicated in the development of surgical sepsis by either promoting or attenuating protective components of the innate immune response. Reducing infective sequelae and the improvement of the quality of care of surgical patients is a top practice priority today. These factors and their associated effects are discussed through the examination of recent clinical and scientific studies to provide an up-to-date evidence-based review.
Dickinson
Ashley
A
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA.
Qadan
Motaz
M
Polk
Hiram C
HC
D001786:Blood Glucose / Q000032:analysis; D001831:Body Temperature / Q000276:immunology*; D016638:Critical Illness; D005334:Fever / Q000276:immunology; D006801:Humans; D007035:Hypothermia / Q000276:immunology; D007113:Immunity, Innate / Q000502:physiology*; D007432:Intraoperative Period; D009000:Monocytes / Q000276:immunology; D011182:Postoperative Care; D018805:Sepsis / Q000276:immunology*; D013530:Surgical Wound Infection / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D001786:Blood Glucose; D014409:Tumor Necrosis Factor-alpha