title: Local recurrence and surveillance after endoscopic resection of large colorectal tumors.
abstract: Local recurrence rates after endoscopic piecemeal mucosal resection (EPMR) typically range from 10 to 23%. In our previous study, the local recurrence rate after a piecemeal resection was significantly higher than that after an en bloc resection, irrespective of tumor size or macroscopic features. To reduce local recurrence after an EPMR, it is important to carefully note the circumferences of the edge and base of the ulcer. Recently, endoscopic submucosal dissection (ESD) was developed and recognized for its effectiveness in large, complete, en bloc resections and precise pathological assessments. ESD also showed lower local recurrence rates, ranging from 0 to 3% in previous, retrospective studies. However, ESD showed a higher perforation rate and longer procedure times; thus, it is necessary to improve ESD. An appropriate surveillance interval after EPMR was still controversial, and recommendations of some guidelines ranged from 2 to 9 months. In order to determine the appropriate interval, a randomized controlled study is necessary.
authors.affiliation: Department of Gastroenterology, Saku Central Hospital, Saku, Nagano, Japan. kinichi1@janis.or.jp
authors.forename: Kinichi
authors.initials: K
authors.lastname: Hotta
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Saito
authors.forename: Takahisa
authors.initials: T
authors.lastname: Matsuda
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Shinohara
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Oyama
mesh_terms: D003082:Colectomy / Q000379:methods*; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000601:surgery*; D019160:Endosonography; D014943:Global Health; D006801:Humans; D015994:Incidence; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000453:epidemiology*; D011159:Population Surveillance / Q000379:methods*