title: Nature of the refractive errors in rhesus monkeys (Macaca mulatta) with experimentally induced ametropias.
abstract: We analyzed the contribution of individual ocular components to vision-induced ametropias in 210 rhesus monkeys. The primary contribution to refractive-error development came from vitreous chamber depth; a minor contribution from corneal power was also detected. However, there was no systematic relationship between refractive error and anterior chamber depth or between refractive error and any crystalline lens parameter. Our results are in good agreement with previous studies in humans, suggesting that the refractive errors commonly observed in humans are created by vision-dependent mechanisms that are similar to those operating in monkeys. This concordance emphasizes the applicability of rhesus monkeys in refractive-error studies.
authors.affiliation: College of Optometry, University of Houston, Houston, TX 77204-2020, United States.
authors.forename: Ying
authors.initials: Y
authors.lastname: Qiao-Grider
authors.forename: Li-Fang
authors.initials: LF
authors.lastname: Hung
authors.forename: Chea-Su
authors.initials: CS
authors.lastname: Kee
authors.forename: Ramkumar
authors.initials: R
authors.lastname: Ramamirtham
authors.forename: Earl L
authors.initials: EL
authors.lastname: Smith
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000867:Anterior Chamber / Q000473:pathology*; D001699:Biometry; D004195:Disease Models, Animal; D007908:Lens, Crystalline / Q000473:pathology*; D008253:Macaca mulatta / Q000502:physiology; D012030:Refractive Errors / Q000503:physiopathology*; D014822:Vitreous Body / Q000473:pathology*