Ileal Crohn's disease: MRI with endoscopic correlation.
OBJECTIVE
To evaluate activity staging of Crohn's disease (CD) measured with MR-enterography using ileoscopy as reference standard.


METHODS
A prospective study was made of 61 patients with CD. All patients underwent MR-enterography and ileoscopy. MRI activity was measured by means of an ad hoc developed score, as well as by analysis of the imaging findings, and was compared with the SES-CD score obtained via ileoscopy. Examinations were performed using a 1.0 T scanner.


RESULTS
MRI score discriminates between active and inactive disease with an area under the ROC curve of 0.941. Overall correlation with the standard reference SES-CD score was moderate to strong (Spearman's r=0.62 p<0.001). Agreement between both methods in staging patients with ileal CD as inactive, mild or moderate to severe was good (Cohen's κ=0.60). Differences in means of the MRI activity scores of the three groups showed statistical significance (p<0.01).


CONCLUSIONS
The MRI score is a reliable predictor of activity in ileal CD and can stage patients in a way comparable to endoscopy. 1.0 T scans are valid for performing radiological evaluation of ileal Crohn's disease.
Gallego
José C
JC
Department of Radiology, Hospital A. Marcide, Ferrol, Spain. josecarlos.gallego.ojea@sergas.es
Echarri
Ana I
AI
Porta
Ana
A
Ollero
Virginia
V
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D019540:Area Under Curve; D002086:Butylscopolammonium Bromide; D003287:Contrast Media; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012372:ROC Curve
D003287:Contrast Media; D002086:Butylscopolammonium Bromide