title: Salivary gland tumor: a review of 599 cases in a Brazilian population.
abstract: Salivary gland tumors consist of a group of heterogeneous lesions with complex clinicopathological characteristics and distinct biological behaviors. Worldwide series show a contrast in the relative incidence of salivary gland tumors, with some discrepancies in clinicopathological data. The main aim of this study was to describe demographic characteristics of 599 cases in a population from Central Brazil over a 10-year period and compare these with other epidemiological studies. Benign tumors represented 78.3% of the cases. Women were the most affected (61%) and the male:female ratio was 1:1.6. Parotid gland tumors were the most frequent (68.5% of cases) and patient age ranged from 1 to 88 years-old (median of 45 years old). The most frequent tumors were pleomorphic adenomas (68.4%) and benign tumors were significantly more frequent in the parotid (75.9%), while malignant tumors were more frequent in the minor salivary glands (40%) (P < 0.05). In conclusion, women and the parotid gland were the most affected and pleomorphic adenoma was the most frequent lesion, followed by adenoid cystic carcinoma and Warthin's tumor.
authors.affiliation: Instituto de Patologia Tropical e Saúde Pública of the Universidade Federal de Goiás, Goiânia-GO, Brazil.
authors.forename: Flávia Aparecida
authors.initials: FA
authors.lastname: de Oliveira
authors.forename: Eliza Carla Barroso
authors.initials: EC
authors.lastname: Duarte
authors.forename: Cláudia Teixeira
authors.initials: CT
authors.lastname: Taveira
authors.forename: Aline Abreu
authors.initials: AA
authors.lastname: Máximo
authors.forename: Erica Carvalho
authors.initials: EC
authors.lastname: de Aquino
authors.forename: Rita de Cássia
authors.initials: Rde C
authors.lastname: Alencar
authors.forename: Eneida Franco
authors.initials: EF
authors.lastname: Vencio
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D055815:Young Adult