[Features of preoperative contrast-enhanced ultrasound of breast cancer: relationship with the syndrome classification in traditional Chinese medicine].
OBJECTIVE
To analyze the relationship between the features of preoperative contrast-enhanced ultrasound and the differentiation of symptoms and signs for syndrome classification by traditional Chinese medicine (TCM).


METHODS
Eighty-two patients with malignant breast tumor were examined with contrast-enhanced ultrasound before the operation. The tumor diameter was greater than 2.0 cm in 48 cases and below 2.0 cm in 34 cases. According to the curative effect standard of TCM disorder, differentiation of symptoms and signs for classification of syndrome were performed, and the ultrasonic manifestations of different syndrome types were compared.


RESULTS
In patients with maximum tumor diameter < or = 2 cm, Chong and Ren disorder type and liver Qi stagnation type were prevalent. In those with tumor diameter of <2 cm, Zeyi liver Qi stagnation type and virtual drug junction were more common. The mass peak intensity, slope of increase, enhancement intensity index and time-intensity curve of ultrasound differed significant between different syndrome types (P<0.05).


CONCLUSIONS
The preoperative ultrasound features of breast cancer are associated with the syndrome types in TCM.
Cai
Li-shan
LS
Department of Ultrasound, Second Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510120, China. Seeyaya @tom.com
Zhang
Jian-xing
JX
Shen
Qiang
Q
Situ
Hong-lin
HL
Song
Guang-hui
GH
Xie
Yin-chang
YC
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000145:classification / Q000000981:diagnostic imaging*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D057234:Preoperative Period; D014463:Ultrasonography
D003287:Contrast Media