KDOQI US commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients.
In response to recently published KDIGO (Kidney Disease: Improving Global Outcomes) guidelines for the care of kidney transplant recipients (KTRs), the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) organized a working group of transplant nephrologists and surgeons to review these guidelines and comment on their relevance and applicability for US KTRs. The following commentaries on the KDIGO guidelines represent the consensus of our work group. The KDIGO transplant guidelines concentrated on aspects of transplant care most important to this population in the posttransplant period, such as immunosuppression, infection, malignancy, and cardiovascular care. Our KDOQI work group concurred with many of the KDIGO recommendations except in some important areas related to immunosuppression, in which decisions in the United States are largely made by transplant centers and are dependent in part on the specific patient population served. Most, but not all, KDIGO guidelines are relevant to US patients. However, implementation of many may remain a major challenge because of issues of limitation in resources needed to assist in the tasks of educating, counseling, and implementing and maintaining lifestyle changes. Although very few of the guidelines are based on evidence that is strong enough to justify their being used as the basis of policy or performance measures, they offer an excellent road map to navigate the complex care of KTRs.
Bia
Margaret
M
Yale School of Medicine, New Haven, CT 06520-8029, USA.
Adey
Deborah B
DB
Bloom
Roy D
RD
Chan
Laurence
L
Kulkarni
Sanjay
S
Tomlanovich
Steven
S
D002985:Clinical Protocols; D003404:Creatinine / Q000097:blood; D005919:Glomerular Filtration Rate; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000592:standards; D007674:Kidney Diseases / Q000601:surgery; D016030:Kidney Transplantation; D008019:Life Style; D008048:Lip Neoplasms / Q000453:epidemiology; D008991:Monitoring, Physiologic / Q000592:standards*; D009369:Neoplasms / Q000453:epidemiology; D011182:Postoperative Care / Q000592:standards*; D017410:Practice Guidelines as Topic; D012878:Skin Neoplasms / Q000453:epidemiology; D014184:Transplantation, Homologous; D014481:United States
D005938:Glucocorticoids; D003404:Creatinine