title: Utility of the Japanese version of the Checklist for Autism in Toddlers for predicting pervasive developmental disorders at age 2.
abstract: We evaluated the utility of the Japanese version of the Checklist for Autism in Toddlers for predicting pervasive developmental disorders (PDD) among 2-year-old children in clinical settings. Confirmed diagnosis revealed that the pass rate on four items (social interest, proto-imperative pointing, proto-declarative pointing and joint-attention) was significantly lower in 52 PDD children than in 48 non-PDD children, and if abnormal development was reported in two or more items, the sensitivity, specificity, and positive/negative predictive values for PDD diagnosis were 0.85, 0.73, and 0.77/0.81, respectively. This simple screening tool can provide valuable information to clinicians when diagnosing PDD.
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan. tomok@ncnp.go.jp
authors.forename: Tomonori
authors.initials: T
authors.lastname: Koyama
authors.forename: Eiko
authors.initials: E
authors.lastname: Inokuchi
authors.forename: Naoko
authors.initials: N
authors.lastname: Inada
authors.forename: Miho
authors.initials: M
authors.lastname: Kuroda
authors.forename: Aiko
authors.initials: A
authors.lastname: Moriwaki
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Katagiri
authors.forename: Madoka
authors.initials: M
authors.lastname: Noriuchi
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kamio
mesh_terms: D044466:Asian People / Q000523:psychology*; D057189:Checklist / Q000295:instrumentation*; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000453:epidemiology*; D002675:Child, Preschool; D004812:Epidemiologic Methods; D006801:Humans; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012680:Sensitivity and Specificity