A case of congenital midline fistula of the upper lip.
Congenital fistulas of the lip are commonly found in the lower lip and accompany cleft lip. They are seen as a symptom of Van der Woude syndrome, which is predominantly hereditary. In contrast, congenital fistulas of the upper lip are rare. A number of hypotheses have been proposed to explain the pathogenesis of fistulas of the upper lip, including fusion failure of facial prominences and absence of mesoblasts, suggesting a relationship between this condition and the development of cleft lip. The pathogenesis of this disorder has been attracting attention. We report the case of a 5-year-old girl with congenital fistula of the upper lip.
Nakano
Yoko
Y
Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Mihama-ku, Chiba, Japan. nakano@tdc.ac.jp
Somiya
Hideki
H
Shibui
Takeo
T
Uchiyama
Takeshi
T
Takano
Nobuo
N
Shibahara
Takahiko
T
Hashimoto
Sadamitsu
S
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007742:Labial Frenum; D008047:Lip Diseases / Q000151:congenital* / Q000601:surgery; D016155:Oral Fistula / Q000151:congenital* / Q000601:surgery; D019647:Oral Surgical Procedures / Q000295:instrumentation*