Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis.
In this study, quantitative trait locus (QTL) analysis was used to identify candidate chromosomes and for detecting the regions that include the gene or genes causing gutter-shaped root (GSR) in AKXL recombinant inbred mouse strains. One potential QTL was detected on chromosome 5 within a region of 13.0 cM, where the likelihood ratio statistic (LRS) score was higher than a suggestive level. This indicates that one of the candidate genes causing mouse GSR may be located in this region.
Tashima
Itaru
I
Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, Yokohama, Japan. Itaru-tashima@tsurumi-u.ac.jp
Arita
Koichiro
K
Asada
Yoshinobu
Y
D000818:Animals; D002874:Chromosome Mapping; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D008126:Lod Score; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D008963:Molar / Q000002:abnormalities*; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics; D040641:Quantitative Trait Loci / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics; D014092:Tooth Root / Q000002:abnormalities*
D005819:Genetic Markers