title: A case of probable mixed-infection with Clonorchis sinensis and Fasciola sp.: CT and parasitological findings.
abstract: We report here a human case probably mixed-infected with Clonorchis sinensis and Fasciola sp. who was diagnosed by computed tomography (CT) scan, serological findings, and/or fecal examination. The patient was a 43-year-old Korean female and was admitted to Kyung Hee University Hospital with the complaints of fever and abdominal pain. On admission, marked eosinophilia was noted in her peripheral blood. CT scan showed specific lesions for clonorchiasis and fascioliasis in the liver, along with lesions suggestive of amebic abscess. Micro-ELISA revealed positive results for the 2 helminthic infections. Eggs of C. sinensis and trophozoites of Entamoeba histolytica were observed in the stool. Treatment with praziquantel followed by metronidazole and tinidazole reduced abnormalities in the liver and eosinophilia. This is the first case report of a possible co-infection with 2 kinds of liver flukes in the Republic of Korea.
authors.affiliation: Department of Medical Zoology, Kyung Hee University, Seoul 130-701, Korea.
authors.forename: Tae Yun
authors.initials: TY
authors.lastname: Kim
authors.forename: Yun-Sik
authors.initials: YS
authors.lastname: Lee
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Yun
authors.forename: Jeong Ju
authors.initials: JJ
authors.lastname: Kim
authors.forename: Won Hyung
authors.initials: WH
authors.lastname: Choi
authors.forename: In Hwan
authors.initials: IH
authors.lastname: Oh
authors.forename: Hyun Ouk
authors.initials: HO
authors.lastname: Song
authors.forename: Jong Phil
authors.initials: JP
authors.lastname: Chu
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000913:Antibodies, Protozoan / Q000097:blood; D003003:Clonorchiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology; D003004:Clonorchis sinensis / Q000302:isolation & purification*; D004748:Entamoeba histolytica / Q000302:isolation & purification; D004802:Eosinophilia / Q000209:etiology; D005209:Fasciola / Q000302:isolation & purification*; D005211:Fascioliasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007723:Korea; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008100:Liver Abscess / Q000175:diagnosis / Q000209:etiology; D008795:Metronidazole / Q000627:therapeutic use; D011223:Praziquantel / Q000627:therapeutic use; D014011:Tinidazole / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000871:Anthelmintics; D000913:Antibodies, Protozoan; D014011:Tinidazole; D008795:Metronidazole; D011223:Praziquantel