Delphian node metastasis in head and neck cancers--oracle or myth?
Delphian node (DN) refers to the pre-laryngeal or pre-cricoid nodal tissue often identified during laryngeal or thyroid surgery. The original nomenclature is based on the assumption that metastasis to this node was predictive of aggressive disease and poor outcome for patients. In this article, we review the existing literature on the topic to determine the significance of DN metastasis in laryngeal, hypopharyngeal and thyroid cancers.
Iyer
N Gopalakrishna
NG
Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Shaha
Ashok R
AR
Ferlito
Alfio
A
Thomas Robbins
K
K
Medina
Jesus E
JE
Silver
Carl E
CE
Rinaldo
Alessandra
A
Takes
Robert P
RP
Suárez
Carlos
C
Rodrigo
Juan P
JP
Bradley
Patrick J
PJ
Werner
Jochen A
JA
D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery