title: Cytoarchitectural differences of myoepithelial cells among goat major salivary glands.
abstract: Previously, the distribution of myoepithelial cells (mecs) in the salivary glands was studied by both immunohistochemistry, and transmission electron microscopy; however, little was elucidated concerning their morphological features, especially in goats. This study was performed to investigate the correlation between the cytoarchitecture of the mecs in goat major salivary glands (parotid, mandibular, and sublingual glands) and the nature of the saliva secretion. The cytoarchitectural features of the mecs were examined by scanning and transmission electron microscopy as well as immunohistochemically. The secretory endpieces in the parotid gland are of the pure serous type, but in both the mandibular and sublingual glands they are of the mixed type. In all studied glands, the intercalated ducts were covered by mecs which, unlike the large stellate cells that surrounded the secretory endpieces, were spindle-shaped with few cytoplasmic processes. Interestingly, the mecs were found to bulge on the basal surfaces of the serous acini and intercalated ducts in all glands and to be in close contact to the seromucous tubules surface in the mandibular and sublingual glands forming a continuous network around it. In conclusion, the differences in the degree of development of the mecs as well as the number of their cytoplasmic processes may be correlated with the nature of the secretion and the number of the secretory granules. Thus these observations may have some relevance in the diagnosis of atrophy and pathogenic conditions of these glands.
authors.affiliation: Laboratory of Anatomy, Department of Biochemical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Yaser Hosny
authors.initials: YH
authors.lastname: Elewa
authors.forename: Mohammad Hafez
authors.initials: MH
authors.lastname: Bareedy
authors.forename: Ahmed Awad
authors.initials: AA
authors.lastname: Abuel-Atta
authors.forename: Ahmed Awad Abu
authors.initials: AA
authors.lastname: Al Atta
authors.forename: Osamu
authors.initials: O
authors.lastname: Ichii
authors.forename: Saori
authors.initials: S
authors.lastname: Otsuka
authors.forename: Tomonori
authors.initials: T
authors.lastname: Kanazawa
authors.forename: Shin-Hyo
authors.initials: SH
authors.lastname: Lee
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kon
mesh_terms: D000818:Animals; D004847:Epithelial Cells / Q000145:classification* / Q000648:ultrastructure*; D005260:Female; D006041:Goats / Q000502:physiology*; D007150:Immunohistochemistry; D008297:Male; D008855:Microscopy, Electron, Scanning; D012469:Salivary Glands / Q000166:cytology*