Clinical efficacy of a novel elimination diet composed of a mixture of amino acids and potatoes in dogs with non-seasonal pruritic dermatitis.
There has been a need for improvement of the elimination diet used for diagnosis of adverse food reaction (AFR) in dogs. Recently, a novel elimination diet composed of a mixture of amino acids and potatoes was developed. We evaluated the efficacy of the elimination diet for diagnosis of AFR in dogs. Twenty dogs that were suspected to have allergic dermatitis were enrolled in a 2-month food elimination trial using the diet. Before and after the trial, the clinical symptoms were evaluated based on the change in canine atopic dermatitis extent and severity index (CADESI), pruritus score and medication score. Of the 20 dogs, 15 completed the food elimination trial. The remaining 5 dogs were removed from the trial because of diet unpalatability, skin disease progression or diarrhea. On the basis of evaluation of the clinical scores, we observed that the clinical symptoms improved in 11 of the 15 dogs that completed the food elimination trial. Provocative challenge was performed in 10 of the 11 dogs that showed improvement in their clinical symptoms. Of the 10 dogs, 7 were diagnosed as having AFR against food ingredients such as pork, beef, chicken and wheat because their skin symptoms reappeared after intake of these ingredients. The results of the food elimination trial and the provocative challenge indicated the usefulness of the novel elimination diet for diagnosis of AFR.
Kawarai
Shinpei
S
First Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
Ishihara
Jun
J
Masuda
Kenichi
K
Yasuda
Nobutaka
N
Ohmori
Keitaro
K
Sakaguchi
Masahiro
M
Asami
Yasuhiro
Y
Tsujimoto
Hajime
H
D017668:Age of Onset; D000485:Allergens / Q000032:analysis; D000596:Amino Acids / Q000008:administration & dosage*; D000821:Animal Feed / Q000009:adverse effects*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000178:diet therapy / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000178:diet therapy* / Q000276:immunology; D004285:Dogs; D005260:Female; D005512:Food Hypersensitivity / Q000662:veterinary*; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D009919:Orchiectomy / Q000662:veterinary; D010052:Ovariectomy / Q000662:veterinary; D011537:Pruritus / Q000178:diet therapy / Q000276:immunology / Q000662:veterinary*; D012720:Severity of Illness Index; D012882:Skin Tests / Q000662:veterinary; D011198:Solanum tuberosum
D000485:Allergens; D000596:Amino Acids; D000900:Anti-Bacterial Agents; D007073:Immunoglobulin E