title: Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi.
abstract: This study characterized a cephalosporin-resistant Salmonella enterica serovar Typhi isolate. The organism possessed a plasmid encoding the CTX-M-15 extended-spectrum-beta-lactamase. This plasmid is the determinant for the phenotype of cephalosporin resistance and is transferrable among Enterobacteriaceae.
authors.affiliation: Department of Bacteriology I, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo, 162-8640, Japan.
authors.forename: Masatomo
authors.initials: M
authors.lastname: Morita
authors.forename: Nobuko
authors.initials: N
authors.lastname: Takai
authors.forename: Jun
authors.initials: J
authors.lastname: Terajima
authors.forename: Haruo
authors.initials: H
authors.lastname: Watanabe
authors.forename: Manabu
authors.initials: M
authors.lastname: Kurokawa
authors.forename: Hiroko
authors.initials: H
authors.lastname: Sagara
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohnishi
authors.forename: Hidemasa
authors.initials: H
authors.lastname: Izumiya
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D012485:Salmonella typhi; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases