One-pot synthesis of azaindoles via palladium-catalyzed alpha-heteroarylation of ketone enolates.
A convenient, one-pot method for the construction of a variety of azaindoles using simple ketones and haloaminopyridines is described.
Spergel
Steven H
SH
Bristol-Myers Squibb, Princeton, New Jersey 08543-4000, USA. steven.spergel@bms.com
Okoro
Danielle R
DR
Pitts
William
W
D001372:Aza Compounds / Q000138:chemical synthesis*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis*; D007659:Ketones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010165:Palladium / Q000737:chemistry*
D001372:Aza Compounds; D007211:Indoles; D007659:Ketones; D010165:Palladium