title: Total synthesis of cryptoacetalide.
abstract: We are reporting the first total synthesis of the tetracyclic terpene natural product cryptoacetalide. Key steps of the synthesis are a microwave-mediated [2+2+2] cyclo-trimerization reaction to construct the central benzene ring, and a light-mediated radical cyclization to assemble the spiro-ketal moiety.
authors.affiliation: Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zou
authors.forename: Alexander
authors.initials: A
authors.lastname: Deiters
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004224:Diterpenes / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure
chemical_list: D004224:Diterpenes; C553736:cryptoacetalide