[Wilson's disease].
Wilson's disease is a disorder of the liver's copper metabolism. Accumulation of copper causes liver and central nervous system damage. Wilson's disease should always be suspected, when a liver disease is detected in a child or an adolescent. The disease may also manifest itself as severe neurological or neuropsychiatric disorders. The diagnosis is often delayed despite the fact that the accumulation of copper in the body can be shown by various means. Early started medication will stop the accumulation of copper into the body. If the treatment is delayed or ineffective, liver transplantation is required.
Moilanen
Veikko
V
Satakunnan keskussairaala, sisätautien klinikka Sairaalantie 3, 28500 Pori.
Mäkisalo
Heikki
H
D003300:Copper / Q000378:metabolism; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008099:Liver / Q000378:metabolism
D003300:Copper