title: Neuraxial anesthesia for a parturient with hypogammaglobulinemia: a case report.
abstract: Hypogammaglobulinemia is characterized as a deficiency in humoral immunity. Humoral immunity deficiencies include the absence of B cells and/or serum immunoglobulins. Common clinical features include a predisposition toward infections naturally defended against through antibody-mediated responses. Clinical manifestations of this condition, in the parturient, may contraindicate neuraxial anesthesia. A 30-year-old parturient with hypogammaglobulinemia was admitted for repeated cesarean delivery and a bilateral tubal ligation. The pathophysiology and anesthetic management of the parturient with hypogammaglobulinemia is discussed.
authors.affiliation: Medical Anesthesia and Pain Consultant Group, Lee Memorial Health Park System, Ft Myers, Florida, USA. bmurza@comcast.net
authors.forename: Barbara
authors.initials: B
authors.lastname: Murza
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000601:surgery*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D009719:Nurse Anesthetists; D011183:Postoperative Complications / Q000517:prevention & control; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000601:surgery*