title: Detection of recurrence by 18F-FDG PET in patients with endometrial cancer showing no evidence of disease.
abstract: This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed (18)F-FDG PET scan. The feasibility of (18)F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on (18)F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of (18)F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, (18)F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer.
authors.affiliation: Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. ryu@kcch.re.kr
authors.forename: Sang-Young
authors.initials: SY
authors.lastname: Ryu
authors.forename: Kidong
authors.initials: K
authors.lastname: Kim
authors.forename: Younha
authors.initials: Y
authors.lastname: Kim
authors.forename: Sang-Il
authors.initials: SI
authors.lastname: Park
authors.forename: Beob-Jong
authors.initials: BJ
authors.lastname: Kim
authors.forename: Moon-Hong
authors.initials: MH
authors.lastname: Kim
authors.forename: Seok-Cheol
authors.initials: SC
authors.lastname: Choi
authors.forename: Eui-Don
authors.initials: ED
authors.lastname: Lee
authors.forename: Kyung-Hee
authors.initials: KH
authors.lastname: Lee
authors.forename: Byung Il
authors.initials: BI
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D019788:Fluorodeoxyglucose F18