Virilizing adrenocortical oncocytoma in a child: a case report.
Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40-60 yr of age. To our knowledge, only 2 cases of functioning adrenocortical oncocytomas have been reported in childhood. We report a case of functioning adrenocortical oncocytoma in a 14-yr-old female child presenting with virilization. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosterone sulfate. She had an adrenalectomy. The completely resected tumor composed predominantly of oncocytes without atypical mitosis and necrosis. A discussion of this case and a review of the literature on this entity are presented.
Lim
Yeon-Jung
YJ
Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea.
Lee
Se-Min
SM
Shin
Jae-Hun
JH
Koh
Hyun-Chul
HC
Lee
Young-Ho
YH
D018249:Adenoma, Oxyphilic / Q000150:complications* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014770:Virilism / Q000209:etiology* / Q000473:pathology / Q000601:surgery