title: Seoul Neuropsychological Screening Battery-dementia version (SNSB-D): a useful tool for assessing and monitoring cognitive impairments in dementia patients.
abstract: The Seoul Neuropsychological Screening Battery (SNSB) is one of the standardized neuropsychological test batteries widely used in Korea. However, it may be a bit too lengthy for patients with decreased attention span; and it does not provide the score of global cognitive function (GCF), which is useful for monitoring patients longitudinally. We sought to validate a dementia version of SNSB (SNSB-D) that was shorter than the original SNSB and contained only scorable tests with a GCF score of 300. We administered SNSB-D to patients with mild cognitive impairment (MCI) (n=43) and Alzheimer's disease (AD) (n=93), and normal controls (NC) (n=77). MCI and AD groups had GCF scores significantly different from NC group, and GCF scores were able to distinguish patients with Clinical Dementia Rating of 0.5 and 1. Test-retest reliability was high, with a correlation coefficient of 0.918 for AD, 0.999 for MCI, and 0.960 for NC. The GCF score significantly correlated with the Mini-Mental State Examination (MMSE). Through ROC-curve analysis, GCF scores were found to yield more accurate diagnoses than the MMSE. The SNSB-D is a valid, reliable tool for assessing the overall cognitive function, and can be used to monitor cognitive changes in patients with dementia.
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Hyun-Jung
authors.initials: HJ
authors.lastname: Ahn
authors.forename: Juhee
authors.initials: J
authors.lastname: Chin
authors.forename: Aram
authors.initials: A
authors.lastname: Park
authors.forename: Byung Hwa
authors.initials: BH
authors.lastname: Lee
authors.forename: Mee Kyung
authors.initials: MK
authors.lastname: Suh
authors.forename: Sang Won
authors.initials: SW
authors.lastname: Seo
authors.forename: Duk L
authors.initials: DL
authors.lastname: Na
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis / Q000503:physiopathology; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D003704:Dementia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007723:Korea; D009483:Neuropsychological Tests / Q000592:standards; D012372:ROC Curve; D015203:Reproducibility of Results; D012720:Severity of Illness Index