title: Capsule endoscopy in small bowel tumors: a multicenter Korean study.
abstract: OBJECTIVE
  Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions in a variety of clinical conditions, but studies concerning the practical impact of CE on small bowel tumors are still scarce, especially in the Asian population. The aim of this study was to evaluate the diagnostic and therapeutic impact of CE in the field of small bowel tumors.
  
  
  METHODS
  CE records consecutively pooled from the beginning of use of CE in Korea, October 2001 until April 2008, in 14 centers throughout Korea were reviewed. Clinical information and CE video images of small bowel tumors were analyzed.
  
  
  RESULTS
  A total of 1332 cases undergoing CE were reviewed with all clinical indications. Small bowel tumors were diagnosed with CE in 57 (4.3%) of 1332 patients. The tumors were malignant in 33 cases, and included three adenocarcinomas, eight lymphomas, 20 gastrointestinal stromal tumors, and two metastatic cancers. The most frequent indications for CE in malignant tumors were obscure gastrointestinal bleeding, followed by abdominal pain and weight loss. Thirty of 57 tumors were identified exclusively by CE (diagnostic impact = 30/57), and they were smaller in size (mean, range: 14.3 mm, 2-35 mm) compared to the other tumors detected in radiological studies (48.7 mm, 10-110 mm). Seven patients underwent surgical resection (therapeutic impact = 7/57).
  
  
  CONCLUSIONS
  CE effectively identifies small bowel tumors that are undetectable by conventional radiological studies (diagnostic impact = 52.6%) and can critically change the therapeutic course (therapeutic impact = 12.3%).
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Cheung
authors.forename: In-Seok
authors.initials: IS
authors.lastname: Lee
authors.forename: Dong Kyung
authors.initials: DK
authors.lastname: Chang
authors.forename: Jin Oh
authors.initials: JO
authors.lastname: Kim
authors.forename: Jae Hee
authors.initials: JH
authors.lastname: Cheon
authors.forename: Byung Ik
authors.initials: BI
authors.lastname: Jang
authors.forename: Yong-Sik
authors.initials: YS
authors.lastname: Kim
authors.forename: Cheol Hee
authors.initials: CH
authors.lastname: Park
authors.forename: Kwang Jae
authors.initials: KJ
authors.lastname: Lee
authors.forename: Ki-Nam
authors.initials: KN
authors.lastname: Shim
authors.forename: Ji-Kon
authors.initials: JK
authors.lastname: Ryu
authors.forename: Jae-Hyuk
authors.initials: JH
authors.lastname: Do
authors.forename: Jeong-Seop
authors.initials: JS
authors.lastname: Moon
authors.forename: Byong Duk
authors.initials: BD
authors.lastname: Ye
authors.forename: Kyung-Jo
authors.initials: KJ
authors.lastname: Kim
authors.forename: Yun Jeong
authors.initials: YJ
authors.lastname: Lim
authors.forename: Myung-Gyu
authors.initials: MG
authors.lastname: Choi
authors.forename: Hoon-Jai
authors.initials: HJ
authors.lastname: Chun
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology; D000328:Adult; D000368:Aged; D053704:Capsule Endoscopy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D015994:Incidence; D007421:Intestine, Small; D007580:Jejunal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D007723:Korea / Q000453:epidemiology; D008223:Lymphoma / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies