Exploiting ultrasound-mediated effects in delivering targeted, site-specific cancer therapy.
Although the concept of employing ultrasound for the treatment of cancer is not a new one, virtually all existing ultrasound-based clinical cancer treatments are based on hyperthermic ablation. This review seeks to highlight the potential offered by more subtle ultrasound-triggered phenomena such as sonoporation in delivering novel targeted cancer treatment modalities.
Nomikou
Nikolitsa
N
University of Ulster, Coleraine, UK.
McHale
Anthony P
AP
D000970:Antineoplastic Agents / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003287:Contrast Media; D016503:Drug Delivery Systems; D006801:Humans; D045423:Microbubbles; D009369:Neoplasms / Q000188:drug therapy / Q000628:therapy*; D014464:Ultrasonic Therapy / Q000379:methods*
D000970:Antineoplastic Agents; D003287:Contrast Media; D001761:Bleomycin