title: [Effect of micronutrients on the immune status of human immunodeficiency virus-positive individuals].
abstract: OBJECTIVE
  To evaluate the effect of micronutrients on the immune status of human immunodeficiency virus (HIV)-positive individuals.
  
  
  METHODS
  Totally 102 HIV-positive individuals were randomly divided into supplementation group (received micronutrients supplement) and control group (received placebo). Physical examinations were performed at baseline and at the end of the trial. Immune status were determined in both two groups.
  
  
  RESULTS
  Age, height, weight, and sex ratio were not significantly different between two groups (all P>0.05). Baseline CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 levels were not significantly different between two groups (all P>0.05), while the levels of CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 were significantly higher in supplementation group than in control group(all P0.05).
  
  
  CONCLUSIONS
  Supplementation of micronutrients can improve the immune status of HIV-positives individuals.
authors.affiliation: Institute of STD and AIDS Prevention, Henan Center for Disease Control and Prevention, Zhengzhou 450016, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Zhao
authors.forename: Xue-Ling
authors.initials: XL
authors.lastname: Feng
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Yan-Min
authors.initials: YM
authors.lastname: Ma
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wang
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Li
mesh_terms: D000328:Adult; D019587:Dietary Supplements; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D018977:Micronutrients / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D018977:Micronutrients