title: An epidemiological survey of hymenoptera venom allergy in the Spanish paediatric population.
abstract: Hypersensitivity reactions to hymenoptera venom are infrequent in paediatric patients. A study was made to determine the incidence of this pathology in children, based on an epidemiological survey targeted to all members of the SEICAP (Sociedad Española de Inmunología Clínica y Alergia Pediátrica/Spanish Society of Paediatric Clinical Immunology and Allergy), and designed to collect the data on patients under 17 years of age diagnosed with hymenoptera venom allergy.
  
  
  RESULTS
  The data corresponding to 175 patients (135 males) were collected. The mean age was 9.9 ± 3.6 years. Seventeen percent (32 patients) were the offspring of beekeepers, and 68.9% had experienced previous stings. The causal insect was Apis melifera, implicated in 55 cases, followed by Polistes dominulus (33 cases). In 151 patients (83.9%) the condition consisted of a local reaction. The most frequent systemic response was urticaria and angio-oedema. Fourteen patients suffered anaphylactic shock. The diagnosis was based on skin test (intradermal and prick) and/or specific IgE testing. Three treatment categories were established: (a) prevention and educational measures; (b) symptomatic treatment with oral antihistamines as well as self-injectable adrenalin; and (c) immunotherapy. In this context, 135 patients underwent immunotherapy with a mean duration of 3.5 ± 1.7 years (range 2-5 years) - with excellent tolerance. The starting regimen was predominantly conventional (92 patients).
  
  
  CONCLUSIONS
  The results of this survey show hypersensitivity reactions to hymenoptera venom to be infrequent in paediatrics, though with a strong impact upon patient quality of life.
authors.affiliation: Sección de Alergia Infantil, Hospital Materno Infantil Virgen de las Nieves de Granada, Spain. anamartinezcanavate@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Martínez-Cañavate
authors.forename: A I
authors.initials: AI
authors.lastname: Tabar
authors.forename: J L
authors.initials: JL
authors.lastname: Eseverri
authors.forename: F
authors.initials: F
authors.lastname: Martín
authors.forename: C
authors.initials: C
authors.lastname: Pedemonte-Marco
mesh_terms: D000485:Allergens / Q000276:immunology*; D000799:Angioedema; D000818:Animals; D001180:Arthropod Venoms / Q000276:immunology*; D056630:Beekeeping; D002648:Child; D003888:Desensitization, Immunologic; D004781:Environmental Exposure; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D006927:Hymenoptera / Q000276:immunology; D006967:Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D007073:Immunoglobulin E / Q000097:blood; D015994:Incidence; D008297:Male; D012882:Skin Tests; D013030:Spain; D014581:Urticaria
chemical_list: D000485:Allergens; D001180:Arthropod Venoms; D007073:Immunoglobulin E