Dynamics of chitosan by (1)h NMR relaxation.
The dynamics of chitosan (CS) in solution have been studied by (1)H NMR relaxation [longitudinal (T(1)) and transverse (T(2)) relaxation times and NOE] as a function of the degrees of acetylation (DA, 1-70) and polymerization (DP, 10-1200), temperature (278-343 K), concentration (0.1-30 g/L), and ionic strength (50-400 mM). This analysis points to CS as a semirigid polymer with increased flexibility at higher DA in agreement with reduced electrostatic repulsions between protonated amino groups.
Novoa-Carballal
Ramon
R
Departamento de Quimica Organica, Facultad de Quimica, and Unidad de RMN de Biomoleculas Asociada al CSIC, Universidad de Santiago de Compostela, Avda. de las Ciencias S.N. 15782 Santiago de Compostela, Spain.
Fernandez-Megia
Eduardo
E
Riguera
Ricardo
R
D000107:Acetylation; D048271:Chitosan / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008970:Molecular Weight; D009994:Osmolar Concentration; D013696:Temperature
D048271:Chitosan