title: RECIST versus volume measurement in medical CT using ellipsoids of known size.
abstract: Two hundred eighty three uniaxial ellipsoids with sizes from 4 mm to 11 mm were measured with a coordinate measuring matching (CMM) and also scanned using a medical computed tomography (CT) machine. Their volumes were determined by counting voxels over a threshold, as well as using equivalent volumes from the length given by the RECIST 1.1 criterion (Response Evaluation Criteria in Solid Tumors). The volumetric measurements yield an order of magnitude reduction in residuals compared to the CMM measurements than the residuals of the RECIST measurements also compared to the CMM measurements.
authors.affiliation: National Institute for Standards and Technology, 100 Bureau Drive, Gaithersburg, Maryland 20899, USA. zlevine@nist.gov
authors.forename: Zachary H
authors.initials: ZH
authors.lastname: Levine
authors.forename: Bruce R
authors.initials: BR
authors.lastname: Borchardt
authors.forename: Nolan J
authors.initials: NJ
authors.lastname: Brandenburg
authors.forename: Charles W
authors.initials: CW
authors.lastname: Clark
authors.forename: Bala
authors.initials: B
authors.lastname: Muralikrishnan
authors.forename: Craig M
authors.initials: CM
authors.lastname: Shakarji
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Chen
authors.forename: Eliot L
authors.initials: EL
authors.lastname: Siegel
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods*