title: Twelve-month follow-up of family communication and psychopathology in children and adolescents with a first psychotic episode (CAFEPS study).
abstract: We analyzed the potential influence of family relationships and history of psychiatric disorders on the presentation and course of early psychotic disorders. We recruited 110 subjects aged 9-17 years with a first psychotic episode and 98 matched healthy controls, and followed them for 1 year. Data were collected through clinical interviews and the Parent-Adolescent Communication Inventory. A family history of psychosis-related disorders was more common in patients' families, with a five-fold higher risk for psychoses related disorders than families of healthy controls. If we consider psychoses related disorder in first-degree relatives, the risk is even higher, rising to 15-fold. The families of patients with a first psychotic episode score themselves worse in communication than the families of healthy controls. More problems in communication at baseline correlated with a higher degree of psychopathology and a lower clinical improvement after 12 months of follow-up.
authors.affiliation: Child and Adolescent Mental Health Unit, Department of Psychiatry and Psychology, Hospital Universitario Marqués de Valdecilla, Santander, Spain. sotero@humv.es
authors.forename: Soraya
authors.initials: S
authors.lastname: Otero
authors.forename: Miguel
authors.initials: M
authors.lastname: Moreno-Iniguez
authors.forename: Beatriz
authors.initials: B
authors.lastname: Payá
authors.forename: Josefina
authors.initials: J
authors.lastname: Castro-Fornieles
authors.forename: Ana
authors.initials: A
authors.lastname: Gonzalez-Pinto
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Baeza
authors.forename: María
authors.initials: M
authors.lastname: Mayoral
authors.forename: Montserrat
authors.initials: M
authors.lastname: Graell
authors.forename: Celso
authors.initials: C
authors.lastname: Arango-López
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D003142:Communication; D005192:Family Health; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D010287:Parent-Child Relations; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000523:psychology*; D018709:Statistics, Nonparametric