title: [Depression and diabetes].
abstract: 11 to 31% of patients with diabetes have depression or clinically significant depressive symptoms. Self-care and compliance of a depressive patient are not always optimal, and depression is independently associated with weakening blood glucose homeostasis. Depression remains undiagnosed in as many as 50 to 75% of cases. Poor glucose homeostasis may exacerbate depression. Treatment of depression in a diabetic patient with the currently most commonly used antidepressants is problematic, since long-term use of these drugs may involve deleterious metabolic effects with regard to diabetes.
authors.affiliation: HUS/HYKS, psykiatrian tulosyksikkö, PL 590, 00029 HUS.
authors.forename: Antero
authors.initials: A
authors.lastname: Leppävuori
mesh_terms: D001786:Blood Glucose / Q000502:physiology; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000503:physiopathology / Q000523:psychology*; D006706:Homeostasis; D006801:Humans
chemical_list: D001786:Blood Glucose