title: Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy.
abstract: Fulminant myocarditis is a rare inflammatory heart disease affecting relatively young adults. We describe a case of a 27-year-old male with acute onset severe heart failure. A rapid and accurate diagnostic approach suggested parvovirus B19 as the most probable cause for this fulminant viral myocarditis. Initial haemodynamic support, intensive immunosuppressive and antiviral therapy resulted in a complete recovery within 2 weeks. This case demonstrates the importance of a detailed diagnosis, allowing better classification of the underlying pathology and subsequent targeted treatment.
authors.affiliation: Department of Cardiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
authors.forename: Robert
authors.initials: R
authors.lastname: Dennert
authors.forename: Sebastiaan
authors.initials: S
authors.lastname: Velthuis
authors.forename: Dirk
authors.initials: D
authors.lastname: Westermann
authors.forename: Dirk
authors.initials: D
authors.lastname: Donker
authors.forename: Simon
authors.initials: S
authors.lastname: Schalla
authors.forename: Robert-Jan
authors.initials: RJ
authors.lastname: van Suylen
authors.forename: Stephane
authors.initials: S
authors.lastname: Heymans
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009205:Myocarditis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D010322:Parvoviridae Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D016732:Parvovirus B19, Human / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents