title: Behavioural abnormalities in children with nephrotic syndrome--an underappreciated complication of a standard treatment?
abstract: Behaviour and psychosocial adjustment are impaired in children with steroid-sensitive idiopathic nephrotic syndrome (SSNS). Both illness-related variables and family climate play a role. Steroid treatment-both short- and long-term-is an important contributor among other determinants. The exact mechanisms by which steroids lead to behavioural alterations in humans is unclear. Optimizing the benefit/risk ratio of steroid treatment in children with SSNS is a constant goal.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Neuhaus
authors.forename: Valerie
authors.initials: V
authors.lastname: Langlois
authors.forename: Christoph
authors.initials: C
authors.lastname: Licht
mesh_terms: D000293:Adolescent; D002648:Child; D002653:Child Behavior Disorders / Q000139:chemically induced* / Q000523:psychology; D002675:Child, Preschool; D005195:Family Relations; D006801:Humans; D007223:Infant; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000523:psychology; D011584:Psychology; D013256:Steroids / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D013256:Steroids