An efficient one-pot synthesis of new 2-imino-1,3-thiazolidin-4-ones under ultrasonic conditions.
A convenient one-pot protocol was developed for the synthesis of 2-imino-1,3-thiazolidin-4-ones by the reaction of amines, isocyanates, aldehydes, and chloroform in the presence of sodium hydroxide under ultrasonic conditions in high yields (75-91%) and shorter reaction times (12-15 min).
Mamaghani
Manouchehr
M
Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran. m-chem41@guilan.ac.ir
Loghmanifar
Azam
A
Taati
Mohammad Reza
MR
D000447:Aldehydes / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D002725:Chloroform / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D017953:Isocyanates / Q000737:chemistry; D012972:Sodium Hydroxide / Q000737:chemistry; D053778:Thiazolidines / Q000138:chemical synthesis* / Q000737:chemistry; D014465:Ultrasonics
D000447:Aldehydes; D000588:Amines; D007097:Imines; D017953:Isocyanates; D053778:Thiazolidines; D012972:Sodium Hydroxide; D002725:Chloroform