First sequential Mukaiyama-Michael reaction/crossed-Claisen condensation using two molar ketene silyl acetals and one molar alpha,beta-unsaturated esters promoted by a NaOH catalyst.
The NaOH-catalyzed first sequential Mukaiyama-Michael reaction/crossed-Claisen condensation is developed using two molar ketene silyl acetals and one molar alpha,beta-unsaturated esters in either a stepwise or one-pot manner.
Tamagaki
Hiroaki
H
Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo, 669-1337, Japan.
Nawate
Yuuya
Y
Nagase
Ryohei
R
Tanabe
Yoo
Y