title: Cervix cancer in Tunisia: clinical and pathological study.
abstract: BACKGROUND
  Uterine cervix cancer is the second most commonly diagnosed cancer among women worldwide.
  
  
  METHODS
  In order to review the clinical and pathological features of cervix cancer in the center of Tunisia, a retrospective study was carried out on 410 cancer cases diagnosed in the Pathology Department, Farhet Hached University Hospital, Sousse, Tunisia (1993-2006).
  
  
  RESULTS
  The mean age was 52.1 years. Of the 410 patients, 90.5% had squamous cell carcinoma and 7.3% had adenocarcinoma. One hundred thirty-eight patients were identified as being in early stages (0 and I) (33.6%) and 58.2% in advanced stages (II-IV). Therapy consisted mainly in combination of radiotherapy and surgery in early stages (28.8%), and radiotherapy alone or associated with the chemotherapy in advanced stage (29.7%). Surgery was the only treatment in 29.5% of cases.
  
  
  CONCLUSIONS
  A relatively large proportion of patients presented in stages II to IV, as compared to only 36% with early stages, emphasizing the need to reinforce the early detection of this cancer and its precursor lesions in the center of Tunisia.
authors.affiliation: Cancer Epidemiology and Cytopathology in the Center of Tunisia, Medicine Faculty, Farhet Hached University Hospital, Sousse, Tunisia. missaouinabiha@live.fr
authors.forename: Nabiha
authors.initials: N
authors.lastname: Missaoui
authors.forename: Sihem
authors.initials: S
authors.lastname: Hmissa
authors.forename: Amel
authors.initials: A
authors.lastname: Trabelsi
authors.forename: Lucien
authors.initials: L
authors.lastname: Frappart
authors.forename: Moncef
authors.initials: M
authors.lastname: Mokni
authors.forename: Sadok
authors.initials: S
authors.lastname: Korbi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D014416:Tunisia / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D014626:Vaginal Smears; D055815:Young Adult