title: [Antibiotic resistance of gramnegative nosocomial pathogens in Minsk ICUs].
abstract: The species pattern and antibiotic resistance of gramnegative isolates from patients with nosocomial infections in Minsk ICUs were studied. Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae and Escherichia coli were the main pathogens, highly resistant to the antibiotics used. Imipenem, meropenem, polymyxin B, ampicillin/sulbactam, amikacin and cefoperazone/sulbactam were the most active antimicrobials against the isolates. The choice of antimicrobials for empirical therapy of hospital infections in ICUs should be based on the local situation regarding the antibiotic resistance, that makes it obligatory to use regular microbiological monitoring in all hospitals thus providing the policy of the use of antimicrobials in ICUs.
authors.forename: G V
authors.initials: GV
authors.lastname: Iliukevich
authors.forename: V M
authors.initials: VM
authors.lastname: Smirnov
authors.forename: N N
authors.initials: NN
authors.lastname: Levshina
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology*; D024881:Drug Resistance, Bacterial; D006090:Gram-Negative Bacteria / Q000254:growth & development* / Q000302:isolation & purification*; D006801:Humans; D007362:Intensive Care Units; D002094:Republic of Belarus / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents