title: Determination of furan levels in commercial samples of baby food from Brazil and preliminary risk assessment.
abstract: Commercial baby food samples available on the Brazilian market (n = 31) were analysed for furan content using a gas chromatography-mass spectrometry method preceded by solid-phase microextraction. A limit of detection of 0.7 microg kg(-1), a limit of quantitation of 2.4 microg kg(-1), mean recoveries varying from 80% to 107%, and coefficients of variation ranging from 5.6% to 9.4% for repeatability and from 7.4% to 12.4% for within-laboratory reproducibility were obtained during an in-house validation. The levels of furan found in the samples were from not detected to 95.5 microg kg(-1). Samples containing vegetables and meat showed higher furan levels as compared with those containing only fruits. An exposure assessment showed furan intakes up to 2.4 microg kg(-1) body weight day(-1) (99th percentile) for babies fed exclusively with commercial baby foods. Margins of exposure obtained from intakes estimated in this work indicated a potential public health concern.
authors.affiliation: Institute of Food Technology, Food Science and Quality Center, CP 139, 13070-178 Campinas, SP, Brazil. adriana.arisseto@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Pavesi Arisseto
authors.forename: E
authors.initials: E
authors.lastname: Vicente
authors.forename: M C
authors.initials: MC
authors.lastname: De Figueiredo Toledo
mesh_terms: D001938:Brazil; D002273:Carcinogens / Q000032:analysis* / Q000737:chemistry; D057140:Fast Foods / Q000032:analysis; D005506:Food Contamination; D005638:Fruit / Q000737:chemistry; D005663:Furans / Q000032:analysis* / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000032:analysis*; D057230:Limit of Detection; D008460:Meat / Q000032:analysis; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods; D052617:Solid Phase Microextraction / Q000379:methods; D014675:Vegetables / Q000737:chemistry
chemical_list: D002273:Carcinogens; D005663:Furans; C039281:furan