title: Overactive bladder: Is there a link to the metabolic syndrome in men?
abstract: It is becoming increasingly clear that a variety of metabolic, cardiovascular, and endocrine factors contribute to male pelvic health. In particular, a growing body of evidence suggests a relationship between lower urinary tract symptoms, benign prostatic hyperplasia, overactive bladder, erectile dysfunction, and the metabolic syndrome. This article explores these relationships, focusing on the role of the autonomic nervous system and hyperinsulinemia, together with their implications for urological practice.
authors.affiliation: Faculty of Health & Human Sciences, Centre for Research in Primary & Community Care (CRIPACC), University of Hertfordshire, College Lane, Hatfield, Herts, UK. kirbym@globalnet.co.uk
authors.forename: Michael G
authors.initials: MG
authors.lastname: Kirby
authors.forename: Adrian
authors.initials: A
authors.lastname: Wagg
authors.forename: Linda
authors.initials: L
authors.lastname: Cardozo
authors.forename: Christopher
authors.initials: C
authors.lastname: Chapple
authors.forename: David
authors.initials: D
authors.lastname: Castro-Diaz
authors.forename: Dirk
authors.initials: D
authors.lastname: de Ridder
authors.forename: Montserrat
authors.initials: M
authors.lastname: Espuna-Pons
authors.forename: Francois
authors.initials: F
authors.lastname: Haab
authors.forename: Con
authors.initials: C
authors.lastname: Kelleher
authors.forename: Heinz
authors.initials: H
authors.lastname: Kölbl
authors.forename: Ian
authors.initials: I
authors.lastname: Milsom
authors.forename: Philip
authors.initials: P
authors.lastname: Van Kerrebroeck
authors.forename: Mark
authors.initials: M
authors.lastname: Vierhout
authors.forename: Stefano
authors.initials: S
authors.lastname: Salvatore
authors.forename: Andrea
authors.initials: A
authors.lastname: Tubaro
mesh_terms: D000818:Animals; D001341:Autonomic Nervous System / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000503:physiopathology; D019317:Evidence-Based Medicine; D006801:Humans; D006946:Hyperinsulinism / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D011470:Prostatic Hyperplasia / Q000453:epidemiology / Q000503:physiopathology; D001743:Urinary Bladder / Q000294:innervation*; D053201:Urinary Bladder, Overactive / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy