[The role of chemotherapy in pediatric medulloblastoma].
Medulloblastoma is one of the most frequent brain tumors in childhood. The mortality of medulloblastoma decreased significantly during the last few decades, which was the result of the better surgical and radiotherapeutic methods and of the development of chemotherapy. The aim of this publication is the critical review of the present chemotherapeutic treatment. The new therapeutic trials based on the molecular genetic mechanism of these tumors are also mentioned.
Schuler
Dezsô
D
Semmelweis Egyetem AOK II. sz. Gyermekgyógyászati Klinika 1094 Budapest Tuzoltó utca 7-9. schdez@gyer2.sote.hu
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000453:epidemiology / Q000235:genetics / Q000378:metabolism*; D002648:Child; D002986:Clinical Trials as Topic; D006801:Humans; D008527:Medulloblastoma / Q000188:drug therapy* / Q000453:epidemiology / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects; D016896:Treatment Outcome