title: Managing comorbid disease in patients with psoriatic arthritis.
abstract: Psoriatic arthritis (PsA) is a unique type of inflammatory arthritis that is associated with skin psoriasis. The concept that PsA is simply a skin and joint disease has been challenged by large epidemiologic studies that link PsA with substantial comorbidity. Important comorbidities related to PsA include premature cardiovascular disease, infectious complications, malignancy risk, osteoporosis, and reduced quality of life. This review focuses on the prevalent comorbid diseases in patients with PsA and highlights how the presence of these associated comorbidities can affect the management of these patients.
authors.affiliation: Cleveland Clinic, Orthopedic and Rheumatologic Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USA. husnie@ccf.org
authors.forename: M Elaine
authors.initials: ME
authors.lastname: Husni
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Mease
mesh_terms: D015535:Arthritis, Psoriatic / Q000150:complications*; D002318:Cardiovascular Diseases / Q000150:complications* / Q000628:therapy; D003866:Depressive Disorder / Q000150:complications* / Q000628:therapy; D006801:Humans; D009765:Obesity / Q000150:complications* / Q000628:therapy; D010024:Osteoporosis / Q000150:complications* / Q000628:therapy; D012307:Risk Factors