[The study of adaptation mechanisms of Yarrowia lipolytica yeast to alkaline conditions by means of proteomics].
Using proteomic technologies--two-dimensional electrophoresis in denaturing conditions in combination with mass spectroscopy of MALDI-TOF proteins--we demonstrated, for the first time, that the most noticeable alteration of protein composition of a Yarrowia lipolytica cell during adaptation to alkaline conditions was an increase of mitochondrial proteins relatively to proteins of cytoplasm.
Guseeva
M A
MA
Epova
E Iu
EIu
Kovalev
L I
LI
Shelev
A B
AB
D000222:Adaptation, Physiological / Q000502:physiology*; D003593:Cytoplasm / Q000378:metabolism*; D005656:Fungal Proteins / Q000096:biosynthesis*; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000096:biosynthesis*; D040901:Proteomics; D025062:Yarrowia / Q000254:growth & development / Q000378:metabolism*
D005656:Fungal Proteins; D024101:Mitochondrial Proteins