title: Digestive Disease Week 2010. Turning Science into Medicine--part 1.
abstract: The Digestive Disease Week 2010 conference, held in New Orleans, included topics covering new therapeutic developments in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. This conference report highlights selected presentations on the novel thiopurine-based immunosuppressive agents B-0N and E-1 (both Giuliani SpA/Friedrich-Alexander-Universitaet Erlangen-Nuernberg); the investigation of ML-3403 (c-a-i-r biosciences GmbH), a p38 MAPK inhibitor for the treatment of chronic inflammatory disease; the development of ALV-003 (Alvine Pharmaceuticals Inc) for the treatment of celiac disease; efficacy studies of AST-120 in patients with irritable bowel syndrome; and a clinical trial evaluating linaclotide (Ironwood Pharmaceuticals Inc/Forest Laboratories Inc/Astellas Pharma Inc/Almirall Prodesfarma SA) withdrawal during chronic constipation therapy.
authors.affiliation: Thomson Reuters, 77 Hatton Garden, London, EC1N 8JS, UK. lisa.hodgkinson@thomsonreuters.com
authors.forename: Lisa
authors.initials: L
authors.lastname: Hodgkinson
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D004066:Digestive System Diseases / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D015507:Drugs, Investigational / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans
chemical_list: D015507:Drugs, Investigational