title: Robust generation of lead compounds for protein-protein interactions by computational and MCR chemistry: p53/Hdm2 antagonists.
authors.affiliation: Max-Planck-Institut für Biochemie, Martinsried, Germany.
authors.forename: Anna
authors.initials: A
authors.lastname: Czarna
authors.forename: Barbara
authors.initials: B
authors.lastname: Beck
authors.forename: Stuti
authors.initials: S
authors.lastname: Srivastava
authors.forename: Grzegorz M
authors.initials: GM
authors.lastname: Popowicz
authors.forename: Siglinde
authors.initials: S
authors.lastname: Wolf
authors.forename: Yijun
authors.initials: Y
authors.lastname: Huang
authors.forename: Michal
authors.initials: M
authors.lastname: Bista
authors.forename: Tad A
authors.initials: TA
authors.lastname: Holak
authors.forename: Alexander
authors.initials: A
authors.lastname: Dömling
mesh_terms: D019295:Computational Biology; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D008958:Models, Molecular; D021381:Protein Transport; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2