title: Comparison of a new whole-body continuous-table-movement protocol versus a standard whole-body MR protocol for the assessment of multiple myeloma.
abstract: OBJECTIVE
  To evaluate a whole body (WB) continuous-table-movement (CTM) MR protocol for the assessment of multiple myeloma (MM) in comparison to a step-by-step WB protocol.
  
  
  METHODS
  Eighteen patients with MM were examined at 1.5T using a WB CTM protocol (axial T2-w fs BLADE, T1-w GRE sequence) and a step-by-step WB protocol including coronal/sagittal T1-w SE and STIR sequences as reference. Protocol time was assessed. Image quality, artefacts, liver/spleen assessability, and the ability to depict bone marrow lesions less than or greater than 1 cm as well as diffuse infiltration and soft tissue lesions were rated. Potential changes in the Durie and Salmon Plus stage and the detectability of complications were assessed.
  
  
  RESULTS
  Mean protocol time was 6:38 min (CTM) compared to 24:32 min (standard). Image quality was comparable. Artefacts were more prominent using the CTM protocol (P = 0.0039). Organ assessability was better using the CTM protocol (P < 0.001). Depiction of bone marrow and soft tissue lesions was identical without a staging shift. Vertebral fractures were not detected using the CTM protocol.
  
  
  CONCLUSIONS
  The new protocol allows a higher patient throughput and facilitates the depiction of extramedullary lesions. However, as long as vertebral fractures are not detectable, the protocol cannot be safely used for clinical routine without the acquisition of an additional sagittal sequence.
authors.affiliation: Department of Clinical Radiology, University Hospital Munich-Grosshadern Campus, Marchioninistr. 15, 81377, Munich, Germany. sabine.weckbach@med.uni-muenchen.de
authors.forename: S
authors.initials: S
authors.lastname: Weckbach
authors.forename: H J
authors.initials: HJ
authors.lastname: Michaely
authors.forename: A
authors.initials: A
authors.lastname: Stemmer
authors.forename: S O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: D J
authors.initials: DJ
authors.lastname: Dinter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009038:Motion; D009101:Multiple Myeloma / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D051598:Whole Body Imaging / Q000379:methods*