Kaposiform hemangioendothelioma of the kidney: an unusual presentation of a rare vascular neoplasm.
Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive, vascular spindle-cell proliferation, with resemblance to Kaposi sarcoma. Usually, this tumor occurs in the skin and the retroperitoneum. We described a girl with a kidney localization and extension into the inferior vena cava and even into the right atrium. The case presented here is unique in 2 ways. First, kidney involvement of KHE has never been described in the literature until now. Second, and most remarkably, extensive tumor thrombosis suggests surgical excision even with cardiopulmonary bypass. The KHE of the kidney is a rare tumor but should be taken into account in the differential diagnosis with other pediatric renal neoplasms.
Indolfi
Paolo
P
Pediatric Department, Pediatric Oncology Service, Second University of Naples, Naples, Italy. paolo.indolfi@unina2.it
Donofrio
Vittoria
V
Fusco
Claudia
C
Di Martino
Martina
M
Di Pinto
Daniela
D
Indolfi
Cristiana
C
Scanderbech
Agostino Maioli Castriota
AM
Casale
Fiorina
F
D002675:Child, Preschool; D005260:Female; D006390:Hemangioendothelioma / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D006801:Humans; D007124:Immunoenzyme Techniques; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D019043:Vascular Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy