title: Genotoxic damage in auto body shop workers.
abstract: Some studies have shown increased DNA damage among car painters, but other professionals working in auto body and paint shops have not been extensively assessed. The aim of this study was to assess DNA damage in different types of auto body shop workers by measuring micronucleus (MN) levels in exfoliated buccal cells. The mean number of cells with MN per 2000 exfoliated buccal cells was analyzed in three groups of male workers: auto body repair technicians, painters, and office workers (control group). All participants answered a questionnaire inquiring about age, smoking habits, alcohol consumption, work practices, occupational exposure time, job activities, and use of protective equipment. The mean number of cells with MN was 3.50 ± 1.50 in auto body painters, 3.91 ± 2.10 in auto body repair technicians, and 0.80 ± 0.78 in office workers, with a significant difference between the control group and the two other groups (p = 0.0001). Age, occupational exposure time, use of protective masks, alcohol consumption, and smoking habit did not affect MN results. The findings indicate that technicians and painters working in auto body shops are at risk for genotoxic damage, while office workers seem to be protected.
authors.affiliation: Biological Sciences Department, Centro Universitário Feevale, Novo Hamburgo, RS, Brazil.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Siebel
authors.forename: Luciano
authors.initials: L
authors.lastname: Basso da Silva
mesh_terms: D000328:Adult; D001336:Automobiles; D016022:Case-Control Studies; D004249:DNA Damage; D006801:Humans; D008297:Male; D048629:Micronuclei, Chromosome-Defective / Q000139:chemically induced*; D015162:Micronucleus Tests; D009061:Mouth Mucosa / Q000166:cytology; D016273:Occupational Exposure; D010150:Paint / Q000506:poisoning*; D012307:Risk Factors; D018709:Statistics, Nonparametric