title: RP-HPLC Method for the Estimation of Dutasteride in Tablet Dosage Form.
abstract: A simple, sensitive and precise RP-HPLC method was developed for the determination of dutasteride in tablet dosage form. The RP-HPLC separation was achieved on phenomenex C(18) column (250 mm, id 4.6 mm, 5 mum) using mobile phase methanol:water (90:10 v/v) at a flow rate of 1 ml/min at an ambient temperature. Quantification was achieved with photodiode array detection at 235 nm over the concentration range 1-12 mug/ml. The method was validated statistically and was applied successfully for the determination of dutasteride in tablets.
authors.affiliation: S. K. Patel College of Pharmaceutical Education & Research, Department of Pharmaceutical Chemistry, Ganpat University, Kherva-382 711, India.
authors.forename: Dipti B
authors.initials: DB
authors.lastname: Patel
authors.forename: N J
authors.initials: NJ
authors.lastname: Patel
authors.forename: S K
authors.initials: SK
authors.lastname: Patel
authors.forename: A M
authors.initials: AM
authors.lastname: Prajapati
authors.forename: S A
authors.initials: SA
authors.lastname: Patel