Exposure to environmental toxins in mothers of children with autism spectrum disorder.
OBJECTIVE
Environmental pollutants, especially environmental toxins (ET), may have the potential to disrupt neurodevelopmental pathways during early brain development. This study was designed to test our hypothesis that mothers with autism spectrum disorder (ASD) children would have less knowledge about ET and more chance to be exposed to ET than mothers with healthy children (MHC).


METHODS
One hundred and six biologic mothers with ASD children (MASD) and three hundred twenty four biologic mothers with healthy children MHC were assessed using two questionnaires asking about ET.


RESULTS
The total score in response to questions related to knowledge about ET in MHC was higher than that in MASD. The possibility of exposure to ET was higher in MASD than MHC. MASD showed higher sub-scale scores in terms of exposures to canned food, plastics, waste incinerators, old electronics, microwavable food, and textiles.


CONCLUSIONS
The current results show that reduced knowledge about ET and greater exposure to ET may be associated with autism spectrum disorder.
Kim
Sun Mi
SM
Department of Psychiatry, Chung Ang University College of Medicine, Seoul, Korea.
Han
Doug Hyun
DH
Lyoo
Hang Sik
HS
Min
Kyung Joon
KJ
Kim
Kyung Ho
KH
Renshaw
Perry
P