title: Spontaneous dural tear leading to intracranial hypotension and tonsillar herniation in Marfan syndrome: a case report.
abstract: BACKGROUND
  We describe the case of a 38 year old male with Marfan syndrome who presented with orthostatic headaches and seizures.
  
  
  METHODS
  The patient was diagnosed with Spontaneous Intracranial Hypotension secondary to CSF leaks, objectively demonstrated by MR myelogram with intrathecal contrast. Epidural autologous blood patch was administered at the leakage site leading to significant improvement.
  
  
  CONCLUSIONS
  Our literature search shows that this is the second reported case of a Marfan patient presenting with symptomatic spontaneous CSF leaks along with tonsillar herniation.
authors.affiliation: Medical College, Aga Khan University Hospital, Stadium Road, P.O. Box 3500, Karachi, Pakistan.
authors.forename: Aqueel H
authors.initials: AH
authors.lastname: Pabaney
authors.forename: Farhan A
authors.initials: FA
authors.lastname: Mirza
authors.forename: Nadir A
authors.initials: NA
authors.lastname: Syed
authors.forename: Humera
authors.initials: H
authors.lastname: Ahsan
mesh_terms: D000328:Adult; D017217:Blood Patch, Epidural; D001921:Brain / Q000473:pathology; D002555:Cerebrospinal Fluid; D003287:Contrast Media; D004388:Dura Mater / Q000473:pathology*; D004677:Encephalocele / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D019585:Intracranial Hypotension / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008382:Marfan Syndrome / Q000150:complications*; D013116:Spinal Cord / Q000473:pathology; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media