title: A human case of subcutaneous dirofilariasis caused by Dirofilaria repens in Vietnam: histologic and molecular confirmation.
abstract: Human dirofilariasis caused by infection with Dirofilaria worms has been frequently reported. The symptoms associated with infection by these filarial parasites, which are transmitted to humans by zooanthropophilic mosquitoes, are characterized by mainly pulmonary and subcutaneous nodules. Here, we report the first case in Vietnam of a subcutaneous dirofilariasis with a painful nodule in the right eyelid. An immature female worm was removed by excisional biopsy and identified as Dirofilaria repens by histology and DNA analysis.
authors.affiliation: Department of Parasitology, National Institute of Malariology, Parasitology and Entomology, No. 245, Luong The Vinh street, Tu Liem, BC 10200, Hanoi, Vietnam. dtcthach@gmail.com
authors.forename: Thi Cam Thach
authors.initials: TC
authors.lastname: Dang
authors.forename: Thu Huong
authors.initials: TH
authors.lastname: Nguyen
authors.forename: Trung Dung
authors.initials: TD
authors.lastname: Do
authors.forename: Shoji
authors.initials: S
authors.lastname: Uga
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Morishima
authors.forename: Hiromu
authors.initials: H
authors.lastname: Sugiyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamasaki
mesh_terms: D000328:Adult; D000818:Animals; D001706:Biopsy; D018509:DNA, Helminth / Q000737:chemistry / Q000235:genetics; D004182:Dirofilaria / Q000302:isolation & purification*; D004184:Dirofilariasis / Q000175:diagnosis* / Q000473:pathology*; D005143:Eyelids / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D012876:Skin Diseases, Parasitic / Q000175:diagnosis* / Q000473:pathology*; D014744:Vietnam
chemical_list: D018509:DNA, Helminth