[Studying efficacy of remaxol in the treatment of respiratory distress syndrome under endotoxicosis conditions].
Chronic model experiments on dogs showed that the development of respiratory distress syndrome under acute pancreatitis conditions is correlated with violation of metabolic processes in the lung tissue, which is caused by activation of the coagulation/lysis system and changes in the lipid metabolism. It is established that remaxol limits the development of inflammatory processes in lungs, produces correction of the lipid metabolism, and introduces positive changes in the coagulation system lung tissues under acute pancreatitis conditions.
Vlasov
A P
AP
Nachkina
E I
EI
Grigor'eva
T I
TI
Tarasova
T V
TV
Potianova
I V
IV
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D004285:Dogs; D004338:Drug Combinations; D005260:Female; D006706:Homeostasis; D050356:Lipid Metabolism / Q000187:drug effects; D008168:Lung / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D010195:Pancreatitis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D013386:Succinates / Q000627:therapeutic use*
D000975:Antioxidants; D004338:Drug Combinations; C555877:Remaxol; D013386:Succinates