title: Efficacy of 10% Povidone Iodine in children affected with early childhood caries: an in vivo study.
abstract: For prevention of dental caries, S. mutans numbers must be reduced and prevented from returning to the original level. An antibacterial agent that is effective and also acceptable to young children can help to establish a favorable oral environment and halt the caries process.
  
  
  OBJECTIVE
  This study was conducted to evaluate the efficacy of topical antimicrobial (10% Povidone- Iodine) on S. mutans counts in children with Early Childhood Caries after full mouth rehabilitation. Also its effects on the clinical outcomes in terms of incidence of new caries and secondary caries were evaluated.
  
  
  METHODS
  Full mouth rehabilitation was done in 30 children (mean age 4.2 years) suffering from Severe Early Childhood Caries (SECC). Stimulated saliva samples were collected to determine the post operative baseline S. mutans counts. Thereafter the subjects were randomly divided into two groups. The experimental group received 10% Povidone Iodine at 3 months interval for a period of 12 months while the control group received placebo (deionized water) at similar intervals. Change in the S.mutans count at 6 and 12 month intervals were compared to the baseline post-operative mutans score. Results revealed that application of 10% Povidone Iodine caused a significant reduction in the rise of Streptococcus mutans levels from the baseline postoperative score after 12 months of treatment thus decreasing the oral load of the organisms. Reduction in counts; in turn decreased the relapse of caries in these children.
  
  
  CONCLUSIONS
  Thus oral rehabilitation coupled with regular application of 10% Povidone Iodine application can be a good alternative to control dental caries in children affected with Early Childhood Caries (ECC).
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Christian Dental College, Ludhiana, Punjab, India. dr_maulisimrat@yahoo.com
authors.forename: Mauli
authors.initials: M
authors.lastname: Simratvir
authors.forename: Namita
authors.initials: N
authors.lastname: Singh
authors.forename: Saroj
authors.initials: S
authors.lastname: Chopra
authors.forename: Abi M
authors.initials: AM
authors.lastname: Thomas
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002675:Child, Preschool; D015169:Colony Count, Microbial; D003188:Composite Resins; D003442:Crowns; D003723:Dental Amalgam; D003731:Dental Caries / Q000382:microbiology / Q000517:prevention & control* / Q000628:therapy; D003764:Dental Materials; D003793:Dental Restoration, Permanent / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D010919:Placebos; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D012463:Saliva / Q000382:microbiology; D013295:Streptococcus mutans / Q000187:drug effects / Q000254:growth & development; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D003188:Composite Resins; D003764:Dental Materials; D010919:Placebos; D003723:Dental Amalgam; D011206:Povidone-Iodine