Differences in testosterone, androstenone, and skatole levels in plasma and fat between pubertal purebred Duroc and Landrace boars in response to human chorionic gonadotrophin stimulation.
The concentrations of the boar taint compounds androstenone and skatole in plasma and fat, together with those of testosterone in plasma, were investigated in pubertal purebred Duroc and Landrace boars following stimulation with human chorionic gonadotrophin (hCG). Higher initial levels of androstenone and testosterone were found in Duroc than Landrace boars. Duroc boars, which were approximately ten days older than the Landrace boars, also showed a more advanced stage of spermatogenesis than Landrace boars. While Landrace boars had the highest skatole levels. Following stimulation with hCG the relative increases in testosterone, androstenone, and skatole concentrations were highest in Landrace boars. The level of androstenone in fat three days after hCG stimulation exceeded 1 microg/g fat in all stimulated boars. The decreases in plasma levels of androstenone and testosterone on Days 2 and 3 after hCG stimulation were more pronounced in Landrace than Duroc boars. However, unlike the plasma androstenone and testosterone levels, the plasma concentrations of skatole did not decrease on Days 2 and 3 following stimulation, but remained elevated on Day 3. These results indicate that the lower levels of testicular steroids in Landrace boars compared with Duroc boars was not due to a lower production capacity, but more likely to a faster disappearance of steroids in Landrace boars. In the present study, age, live weight, and testicular development did not significantly contribute to the variation in fat androstenone. The present data and previous reports on candidate genes related to androstenone biosynthesis and metabolism suggests that future selection against factors associated with boar taint remains a possible solution for the problem of boar taint in the swine industry.
Oskam
I C
IC
The Norwegian School of Veterinary Science, Department of Production Animal Clinical Sciences. P.B. 8146, NO-0033 Oslo, Norway. irma.oskam@rikshospitalet.no
Lervik
S
S
Tajet
H
H
Dahl
E
E
Ropstad
E
E
Andresen
Ø
Ø
D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism; D000367:Age Factors; D000738:Androsterone / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D001947:Breeding; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D004247:DNA / Q000032:analysis; D008297:Male; D010949:Plasma / Q000187:drug effects* / Q000378:metabolism; D012741:Sexual Maturation / Q000502:physiology; D012862:Skatole / Q000097:blood / Q000378:metabolism*; D013045:Species Specificity; D013087:Spermatids / Q000187:drug effects / Q000378:metabolism; D013552:Swine / Q000097:blood / Q000378:metabolism; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
D006063:Chorionic Gonadotropin; D013739:Testosterone; D004247:DNA; D012862:Skatole; D000738:Androsterone