"Clickable" polymer nanoparticles: a modular scaffold for surface functionalization.
The versatility of copper-catalyzed alkyne-azide coupling (CuAAC) in functionalizing drug-loaded polymer nanoparticles is demonstrated via the modification of surfaces of acetylene-functionalized PNPs with folate, biotin, and gold nanoparticles.
Krovi
Sai Archana
SA
Department of Chemistry and The International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
Smith
DeeDee
D
Nguyen
SonBinh T
ST
D000475:Alkenes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties
D000475:Alkenes; D001386:Azides; D011108:Polymers; D006046:Gold; D003300:Copper