Five classic articles in genetic epidemiology.
The relatively new field of genetic epidemiology has witnessed some exciting leaps forward in our quest to understand the population and familial nature of genetic inheritance. We have witnessed the mapping of thousands of genetic loci contributing to both mendelian and complex diseases, and new high-throughput, low-cost sequencing technologies promise to uncover even more. Here I highlight five publications that have shaped how we think about and conduct the task of unraveling the genetic causes of disease on a population scale.
DeWan
Andrew T
AT
Yale School of Public Health, New Haven, Connecticut 06520-8034, USA. andrew.dewan@yale.edu
D008040:Genetic Linkage; D015894:Genome, Human; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008233:Lymphotoxin-alpha / Q000235:genetics; D017720:Molecular Epidemiology / Q000266:history*; D009203:Myocardial Infarction / Q000235:genetics; D010375:Pedigree; D020641:Polymorphism, Single Nucleotide; D011995:Recombination, Genetic
D008233:Lymphotoxin-alpha