title: [Study on extraction of anti-diabetes active constituents from Potentilla chinesis].
abstract: OBJECTIVE
  To study the extraction technology of anti-diabetes active constituents from Potentilla chinesis.
  
  
  METHODS
  Through single factor test, the effects of factors such as concentration of ethanol, temperature, ratio of liquid-solid, extraction time and times of extraction were investigated. Through orthogonal experiment, the optimal conditions of extraction were obtained on the basis of single factor test.
  
  
  RESULTS
  The optimum extraction conditions of Potentilla flavone from P. chinesis were determined as follows: refluxing for 3 times, 1.5 hours each time, and 8-6-6 for the multiple of 60% EtOH and material.
  
  
  CONCLUSIONS
  The extraction process is stable and suitable for industry.
authors.affiliation: Tianjin Research Center of Basic Medical Science, School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhao
authors.forename: Sheng-an
authors.initials: SA
authors.lastname: Tang
authors.forename: Hong-quan
authors.initials: HQ
authors.lastname: Duan
mesh_terms: D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000737:chemistry; D047309:Flavones / Q000032:analysis / Q000302:isolation & purification*; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031987:Potentilla / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods; D013696:Temperature; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D047309:Flavones; D007004:Hypoglycemic Agents; D000431:Ethanol; C043562:flavone