title: The safety and efficacy of ablative techniques adjacent to the hepatic vasculature and biliary system.
abstract: Ablative techniques may provide an alternative to resection in treating awkwardly placed hepatic malignancy adjacent to major vascular and biliary structures. The heat-sink effect may reduce efficacy adjacent to major vascular structures. Vascular occlusion improves efficacy but is associated with increased vascular and biliary complications. The safety and efficacy of ablation in these situations remain to be defined. Further studies comparing both safety and efficacy are needed.
authors.affiliation: Department of Hepatobiliary and Pancreatic Surgery, University Hospitals of Leicester, Gwendolen Road, Leicester, UK. chris.mann@doctors.org.uk
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Mann
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Metcalfe
authors.forename: David M
authors.initials: DM
authors.lastname: Lloyd
authors.forename: Guy J
authors.initials: GJ
authors.lastname: Maddern
authors.forename: Ashley R
authors.initials: AR
authors.lastname: Dennison
mesh_terms: D055011:Ablation Techniques / Q000009:adverse effects; D000818:Animals; D001652:Bile Ducts / Q000293:injuries; D017115:Catheter Ablation; D006489:Hemostatic Techniques; D006499:Hepatic Artery / Q000293:injuries; D006503:Hepatic Veins / Q000293:injuries; D006801:Humans; D008099:Liver / Q000098:blood supply*; D008113:Liver Neoplasms / Q000601:surgery*; D008872:Microwaves; D011169:Portal Vein / Q000293:injuries; D011183:Postoperative Complications / Q000517:prevention & control; D012449:Safety