Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells.
Internalization and dynamic subcellular distribution of thiol-capped CdTe quantum dots (QDs) in living cells were studied by means of laser scanning confocal microscopy. These unfunctionalized QDs were well internalized into human hepatocellular carcinoma and rat basophilic leukemia cells in vitro. Co-localizations of QDs with lysosomes and Golgi complexes were observed, indicating that in addition to the well-known endosome-lysosome endocytosis pathway, the Golgi complex is also a main destination of the endocytosed QDs. The movement of the endocytosed QDs toward the Golgi complex in the perinuclear region of the cell was demonstrated.


BACKGROUND
The online version of this article (doi:10.1007/s11671-009-9307-9) contains supplementary material, which is available to authorized users.
Zhang
Yu
Y
Mi
Lan
L
Xiong
Rongling
R
Wang
Pei-Nan
PN
Chen
Ji-Yao
JY
Yang
Wuli
W
Wang
Changchun
C
Peng
Qian
Q