title: Escape from X inactivation in mice and humans.
abstract: A subset of X-linked genes escapes silencing by X inactivation and is expressed from both X chromosomes in mammalian females. Species-specific differences in the identity of these genes have recently been discovered, suggesting a role in the evolution of sex differences. Chromatin analyses have aimed to discover how genes remain expressed within a repressive environment.
authors.affiliation: Department of Pathology, University of Washington, Seattle, Washington 98195, USA.
authors.forename: Joel B
authors.initials: JB
authors.lastname: Berletch
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Christine M
authors.initials: CM
authors.lastname: Disteche
mesh_terms: D000818:Animals; D042002:Chromatin Assembly and Disassembly / Q000235:genetics; D004194:Disease / Q000235:genetics; D018392:Genomic Imprinting / Q000235:genetics; D006801:Humans; D008540:Meiosis / Q000235:genetics; D051379:Mice; D012730:Sex Chromosomes / Q000235:genetics; D049951:X Chromosome Inactivation / Q000235:genetics*