Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines.
We report on novel 3-arylamino-6-benzylamino-1,2,4,5-tetrazines with potent activity against Plasmodium falciparum.
Nhu
Duong
D
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Duffy
Sandra
S
Avery
Vicky M
VM
Hughes
Andrew
A
Baell
Jonathan B
JB
D000962:Antimalarials / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D001596:Benzylamines / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D010963:Plasmodium falciparum / Q000187:drug effects; D013329:Structure-Activity Relationship; D013777:Tetrazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity
D000962:Antimalarials; D001596:Benzylamines; D013777:Tetrazoles