title: [Photobiochemistry of folates: a photochemical reduction of folic acid].
abstract: Exposure of deaerated folic acid solutions containing an electron donor to UV radiation (310-390 nm, I = 0.4 W m(-2)) induced formation of dihydrofolic acid (DHFA), a photoexcitation which gave tetrahydrofolic acid (THFA). Only DHFA was formed in the presence of EDTA (E'o = +0.40 V), while the presence of stronger reductants-NADH (E'o = -0.32 V) and boron hydride (E'o = -0.48 V)-induced photoreduction to THFA. It was demonstrated that UV radiation had no effect on the THFA formylation, giving the coenzyme 5,10-methenyltetrahydrofolic acid and its transformation into another coenzyme, 5-formyltetrahydrofolic acid.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Vechtomova
authors.forename: T A
authors.initials: TA
authors.lastname: Telegina
authors.forename: M P
authors.initials: MP
authors.lastname: Kolesnikov
authors.forename: M S
authors.initials: MS
authors.lastname: Kritskiĭ
mesh_terms: D004492:Edetic Acid / Q000737:chemistry*; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*; D055668:Photochemical Processes; D013763:Tetrahydrofolates / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D013763:Tetrahydrofolates; C010920:dihydrofolate; C030371:5,6,7,8-tetrahydrofolic acid; D005492:Folic Acid; D004492:Edetic Acid