title: [Correlations of sister chromatids cohesion complexes distribution with histones H3 and H4 modifications].
abstract: The formulation of "histone code" theory brings active investigations of the role of histone modifications and other supramolecular factors of DNA condensation in transcription regulation. In this work, we have analyzed the localization of methylated histones on 9, 36 and 79 lysines, hyperacetylated H4 histone, and subunits of cohesion complex DRAD21 relatively of Drosophila melanogaster polytene chromosomes chromatin condensation. We propose the hypotheses of a cascade regulation of transcription activity defined by histone modifications and the adaptive role of sister chromatids cohesion in the transcription of high active and extensive genes.
authors.forename: A V
authors.initials: AV
authors.lastname: Markov
authors.forename: A A
authors.initials: AA
authors.lastname: Zakharov
authors.forename: N S
authors.initials: NS
authors.lastname: Rodionova
authors.forename: A A
authors.initials: AA
authors.lastname: Mikhaĭlutsa
authors.forename: A V
authors.initials: AV
authors.lastname: Strunnikov
authors.forename: A F
authors.initials: AF
authors.lastname: Smirnov
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism*; D002842:Chromatids / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis / Q000378:metabolism; D002874:Chromosome Mapping; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000235:genetics / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D008745:Methylation
chemical_list: D018797:Cell Cycle Proteins; D002868:Chromosomal Proteins, Non-Histone; D029721:Drosophila Proteins; D006657:Histones; C410884:vtd protein, Drosophila