title: Strategy for Prevention of Restenosis after PTA. Clinical and Basic Approaches.
abstract: Percutaneous transluminal angioplasty (PTA) has been a useful therapy to treat stenosis of cervical internal carotid artery (ICA) or vertebral artery (VA). Here we show that our clinical results regarding preventive effect of stenting on restenosis after PTA in the ICA and VA origin. We also show our experimental studies with gene transfer techniques aiming reduction of restenosis after balloon-injury in rat carotid artery. It has been reported that drug-eluting stent inhibits restenosis after coronary angioplasty. Further understanding of the mechanism of restenosis and application of these new modalities may lead to better clinical results in angioplasty of the craniocervical arteries.
authors.affiliation: Department of Neurosurgery, Gifu University School of Medicine, Gifu; Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yoshimura
authors.forename: Y
authors.initials: Y
authors.lastname: Kaku
authors.forename: J
authors.initials: J
authors.lastname: Kokuzawa
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: N
authors.initials: N
authors.lastname: Sakai