A cope rearrangement-based route to hexahydroazulenes.
2-exo-Vinyl-7-alkylidenenorbornanes, readily prepared from fulvene Diels-Alder adducts, undergo smooth Cope rearrangement at elevated temperatures to produce hexahydroazulene derivatives.
Seizert
Curtis A
CA
Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.
Bumbu
Valentina D
VD
Birman
Vladimir B
VB
D052176:Azulenes / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D009636:Norbornanes / Q000737:chemistry*
D052176:Azulenes; D009636:Norbornanes