title: Extensive hypertrophic lichen planus in an HIV positive patient.
abstract: Individuals who are infected with Human Immunodeficiency Virus (HIV) suffer from numerous dermatoses. These disorders are often more severe than those observed in non HIV-infected persons afflicted with the same diseases. Lichen planus (LP) is a chronic inflammatory papulosquamous skin disorder. Herein, the diagnosis and treatment of a 40-year-old HIV+ Kenyan man afflicted with hypertrophic lichen planus (HLP) is described. In this case, lesions of HLP were widely distributed across the trunk and extremities, having become of such thickness on the dorsal surfaces of the hands and fingers as to make normal use of hands impossible. A significant distinguishing feature of this patient is prior history of tuberculosis, which is a known trigger for lichenoid skin lesions.
authors.affiliation: Red Crescent Society of the Islamic Republic of Iran Research and Medical Center, Nairobi, Kenya. naseremad@yahoo.com
authors.forename: Seyed Naser
authors.initials: SN
authors.lastname: Emadi
authors.forename: Jamal
authors.initials: J
authors.lastname: Akhavan-Mogaddam
authors.forename: Maryam
authors.initials: M
authors.lastname: Yousefi
authors.forename: Bahman
authors.initials: B
authors.lastname: Sobhani
authors.forename: Abbas
authors.initials: A
authors.lastname: Moshkforoush
authors.forename: Seyed Emad
authors.initials: SE
authors.lastname: Emadi
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002990:Clobetasol / Q000627:therapeutic use; D004338:Drug Combinations; D015658:HIV Infections / Q000150:complications*; D006229:Hand Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D008297:Male; D019829:Nevirapine / Q000627:therapeutic use; D011537:Pruritus / Q000188:drug therapy; D018119:Stavudine / Q000627:therapeutic use; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications
chemical_list: D019380:Anti-HIV Agents; D004338:Drug Combinations; C516355:stavudine, lamivudine, nevirapine drug combination; D019259:Lamivudine; D019829:Nevirapine; D002990:Clobetasol; D018119:Stavudine