Acculturation, childhood trauma and the cortisol awakening response in Mexican-American adults.
Exposure to chronic and traumatic stress has been associated with the dysregulation of crucial stress response systems. Acculturation has been associated with unique forms of chronic psychosocial stress. The purpose of this study was to examine the effects of exposure to early traumatic stress and acculturation on dysregulation of the cortisol awakening response (CAR) in Mexican-American adults. Salivary cortisol samples were collected at awakening and 30, 45, and 60 min thereafter, on two consecutive weekdays from 59 healthy Mexican-American adult males (26) and females (33), ages 18-38 years. Participants were assessed for level of acculturation and exposure to early trauma. Data were analyzed using a mixed effects regression model with repeated measures at four time points. Mixed effects regression results indicated a significant Early Trauma x Time interaction (p=.0029) and a significant Acculturation x Time interaction (p=.0015), after controlling for age and sex. Subsequent analyses of the interaction of Trauma x Acculturation x Time showed that more than minimal exposure to either risk factor was associated with attenuation of the awakening cortisol response (p=.0002). Higher levels of acculturation with greater Anglo-orientation were associated with attenuation of the CAR in Mexican-American adults. Both moderate and higher levels of exposure to early trauma were associated with an attenuated CAR. However, greater exposure to both risk factors was only incrementally worse than exposure to either one.
Mangold
Deborah
D
The University of Texas at San Antonio, 6900 North Loop 1604 West, San Antonio, TX 78249, USA. dmangold@utsa.edu
Wand
Gary
G
Javors
Martin
M
Mintz
James
J
D000069:Acculturation; D000223:Adaptation, Psychological / Q000502:physiology; D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D002648:Child; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000378:metabolism*; D008297:Male; D017058:Mexican Americans / Q000706:statistics & numerical data; D012463:Saliva / Q000737:chemistry / Q000378:metabolism; D013315:Stress, Psychological / Q000453:epidemiology / Q000208:ethnology / Q000378:metabolism*; D014851:Wakefulness / Q000502:physiology; D055815:Young Adult
D006854:Hydrocortisone