title: Delphian node metastasis in head and neck cancers--oracle or myth?
abstract: Delphian node (DN) refers to the pre-laryngeal or pre-cricoid nodal tissue often identified during laryngeal or thyroid surgery. The original nomenclature is based on the assumption that metastasis to this node was predictive of aggressive disease and poor outcome for patients. In this article, we review the existing literature on the topic to determine the significance of DN metastasis in laryngeal, hypopharyngeal and thyroid cancers.
authors.affiliation: Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
authors.forename: N Gopalakrishna
authors.initials: NG
authors.lastname: Iyer
authors.forename: Ashok R
authors.initials: AR
authors.lastname: Shaha
authors.forename: Alfio
authors.initials: A
authors.lastname: Ferlito
authors.forename: K
authors.initials: K
authors.lastname: Thomas Robbins
authors.forename: Jesus E
authors.initials: JE
authors.lastname: Medina
authors.forename: Carl E
authors.initials: CE
authors.lastname: Silver
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rinaldo
authors.forename: Robert P
authors.initials: RP
authors.lastname: Takes
authors.forename: Carlos
authors.initials: C
authors.lastname: Suárez
authors.forename: Juan P
authors.initials: JP
authors.lastname: Rodrigo
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Bradley
authors.forename: Jochen A
authors.initials: JA
authors.lastname: Werner
mesh_terms: D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery