Investigation of integrons/cassettes in antimicrobial-resistant Escherichia coli isolated from food animals in China.
In this study, 326 Escherichia coli isolates from food animals collected during the last four decades in China were characterized using antimicrobial susceptibility testing and screening for integrons/cassettes. Minimum inhibitory concentration (MIC) testing indicated that the antimicrobial resistance of E. coli has increased since the 1970s. The findings of this study present a warning to veterinary practitioners about the excessive use of antimicrobials, and suggest the necessity for surveillance and control of antimicrobial resistance in veterinary clinical medicine in China.
Song
Li
L
China Institute of Veterinary Drug Control, Beijing, 100081, China. songli@indc.gov.cn
Ning
Yibao
Y
Shen
Jianzhong
J
Fan
Xuezheng
X
Zhang
Chunping
C
Yang
Chenghuai
C
Han
Jianfeng
J
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D002417:Cattle; D002645:Chickens; D002681:China; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics*; D032023:Integrons / Q000235:genetics*; D013552:Swine
D000890:Anti-Infective Agents