title: Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature.
abstract: Cancer metastasis to the thyroid is extremely rare. The more commonly reported primary sites for metastasis to the thyroid are the kidney, breast, lung, colon, esophagus, and uterus. Thyroid metastasis from the stomach has only been reported in three cases. Herein, we report a 71-year-old man presenting with bilateral thyroid multinodular lesions. Bilateral near-total thyroidectomy was performed due to airway compression with related symptoms. Wedge resection of a suspicious pulmonary nodule, detected on CT, was performed for diagnosis. Polypoid lesions in the stomach were examined by trans-scopic biopsy. Poorly differentiated adenocarcinomas with the same histological profiles were noted at these three sites. The immunohistochemical staining for thyroglobulin of these specimens was negative. We conclude that a new thyroid mass appearing in a patient with present or prior malignancies should raise the concern of metastatic disease.
authors.affiliation: Department of Surgery, St. Martin de Porres Hospital, Chia-Yi City, Taiwan, China.
authors.forename: Hwa-chan
authors.initials: HC
authors.lastname: Lee
authors.forename: Fen-fen
authors.initials: FF
authors.lastname: Chen
authors.forename: Ching-chu
authors.initials: CC
authors.lastname: Lo
authors.forename: Chung-jing
authors.initials: CJ
authors.lastname: Wang
authors.forename: Wei-chun
authors.initials: WC
authors.lastname: Lo
authors.forename: Shi-ping
authors.initials: SP
authors.lastname: Luh
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male; D013274:Stomach Neoplasms / Q000175:diagnosis; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000556:secondary*