Coronary revascularisation in chronic kidney disease. Part II: acute coronary syndromes.
Chronic kidney disease (CKD) is associated with a high burden of coronary artery disease, myocardial infarction and cardiovascular death. Management of patients with CKD presenting with acute coronary syndromes is more complex than in the general population, due to greater diagnostic uncertainty and the lack of direct evidence for therapeutic interventions in this specific population, coupled with concerns about therapy-related adverse effects. However, these patients potentially have much to gain from conventional revascularisation strategies used in the general population. This review summarises the current evidence regarding the treatment of patients with CKD presenting with acute coronary syndromes, in particular with respect to coronary revascularisation strategies.
Seddon
Mike
M
Wessex Cardiac Unit, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK.
Curzen
Nick
N
D054058:Acute Coronary Syndrome / Q000401:mortality / Q000451:nursing* / Q000503:physiopathology / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary / Q000451:nursing*; D005919:Glomerular Filtration Rate / Q000502:physiology; D017052:Hospital Mortality; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000451:nursing* / Q000503:physiopathology*; D009203:Myocardial Infarction / Q000401:mortality / Q000451:nursing / Q000503:physiopathology / Q000628:therapy; D009204:Myocardial Revascularization / Q000451:nursing*; D016032:Randomized Controlled Trials as Topic; D015607:Stents; D015996:Survival Rate; D015912:Thrombolytic Therapy / Q000451:nursing