title: The wrath of RAFs: rogue behavior of B-RAF kinase inhibitors.
authors.forename: Fred M
authors.initials: FM
authors.lastname: Kaplan
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Mastrangelo
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Aplin
mesh_terms: D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000009:adverse effects*; D020935:MAP Kinase Signaling System / Q000187:drug effects*; D008545:Melanoma / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D047428:Protein Kinase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects*; D000077484:Vemurafenib
chemical_list: D007211:Indoles; D047428:Protein Kinase Inhibitors; D013449:Sulfonamides; D000077484:Vemurafenib; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf