title: Cobalt-catalyzed 1,4-hydrovinylation of allylsilane and allylboronic esters for the synthesis of hydroxy-functionalized 1,4-dienes.
abstract: The cobalt(I)-catalyzed 1,4-hydrovinylation reaction of allyl trimethylsilane and allyl pinacol boronic ester with symmetrical and unsymmetrical 1,3-dienes generates building blocks for the in situ allylboration or the Lewis acid induced allylation reaction utilizing the corresponding allyl silane derivatives. The products of these three-component reactions are hydroxy-functionalized 1,4-dienes which can be used for the synthesis of pyranones. An alternate reaction sequence for the synthesis of the hydroxy-functionalized 1,4-dienes by performing the allylation first followed by the cobalt-catalyzed 1,4-hydrovinylation is also possible. Accordingly, polyfunctionalized complex structures can be generated by both approaches in a convergent fashion.
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg, 35043 Marburg, Germany.
authors.forename: Marion
authors.initials: M
authors.lastname: Arndt
authors.forename: Anne
authors.initials: A
authors.lastname: Reinhold
authors.forename: Gerhard
authors.initials: G
authors.lastname: Hilt