title: De novo synthesis and lectin binding studies of unsaturated carba-pyranoses.
abstract: Starting from branched para-benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy.
authors.affiliation: Bergische University Wuppertal, Gaussstrasse 20, 42097, Wuppertal, Germany. timo.leermann@broteleermann.de
authors.forename: Timo
authors.initials: T
authors.lastname: Leermann
authors.forename: Oliver
authors.initials: O
authors.lastname: Block
authors.forename: Michael A L
authors.initials: MA
authors.lastname: Podeschwa
authors.forename: Uwe
authors.initials: U
authors.lastname: Pfüller
authors.forename: Hans-Josef
authors.initials: HJ
authors.lastname: Altenbach
mesh_terms: D054329:Carbasugars / Q000138:chemical synthesis / Q000737:chemistry*; D037102:Lectins / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D054329:Carbasugars; D037102:Lectins