Adenocarcinoma of the upper aerodigestive tract.
Although squamous cell carcinoma is the most frequent malignant diagnosis made with upper aerodigestive tract specimens, a myriad of neoplasms can occur throughout the area. Very uncommonly, one encounters adenocarcinomas that cannot be better classified as salivary gland-type neoplasia. This manuscript reviews these tumors, including sinonasal intestinal-type adenocarcinomas, sinonasal low-grade and high-grade nonintestinal adenocarcinomas and nasopharyngeal papillary adenocarcinomas. Clinical, histologic, and immunohistochemical features and differential diagnoses are discussed.
Stelow
Edward B
EB
Department of Pathology, University of Virginia, Charlottesville, USA.
Mills
Stacey E
SE
Jo
Vickie Y
VY
Carlson
Diane L
DL
D000230:Adenocarcinoma / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000473:pathology; D012142:Respiratory Tract Neoplasms / Q000473:pathology*