title: [Rheumatic diseases: current technologies and perspectives of laboratory diagnosis].
abstract: The problems of the laboratory diagnosis of rheumatic diseases (RD), by determining a broad spectrum of biomarkers at the cellular and humoral levels, are considered. Serological assays aimed at detecting circulating autoantibodies are noted to hold a central position in the laboratory diagnosis of RD. Measurement of the blood levels of inflammatory markers maintains its diagnostic value; it is shown to be important to multiplex analysis, a fundamentally new laboratory technique in rheumatology.
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: E N
authors.initials: EN
authors.lastname: Aleksandrova
mesh_terms: D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D019411:Clinical Laboratory Techniques / Q000639:trends; D016207:Cytokines / Q000097:blood; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D012216:Rheumatic Diseases / Q000097:blood / Q000175:diagnosis* / Q000276:immunology
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D016207:Cytokines; D007136:Immunoglobulins