title: Amyloidosis secondary to xanthogranulomatous pyelonephritis: a rare association.
abstract: Xanthogranulomatous pyelonephritis and secondary systemic amyloidosis are relatively common pathologies with innumerable cases being reported now and then. However the association of these entities is an extremely uncommon occurrence with only ten cases described in the literature. Clinical remission of amyloidosis develops in a majority of these patients after removal of the renal lesion. We present a case of this rare association in a young female who under-went nephrectomy for a non-functioning kidney. A histopathological diagnosis of xanthogranulomatous pyelonephritis was made. In addition there were deposits of amyloid in the glomeruli and the interstitial blood vessels.
authors.affiliation: Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
authors.forename: Rajpal Singh
authors.initials: RS
authors.lastname: Punia
authors.forename: Neerja
authors.initials: N
authors.lastname: Dhingra
authors.forename: Harsh
authors.initials: H
authors.lastname: Mohan
authors.forename: Sanjay
authors.initials: S
authors.lastname: D'Cruz
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000097:blood / Q000209:etiology* / Q000473:pathology; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000473:pathology*; D009392:Nephrectomy; D011705:Pyelonephritis, Xanthogranulomatous / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome