Intestinal stem cell asymmetric division in the Drosophila posterior midgut.
Over the past 2 years, our understanding of intestinal stem cells in the Drosophila posterior midgut has advanced greatly. In this review, I will focus on the establishment of these stem cells in their niche during development and the molecular mechanisms that regulate their asymmetric division in adults.
Hou
Steven X
SX
National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA. hous@mail.nih.gov
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D002455:Cell Division / Q000502:physiology*; D049109:Cell Proliferation; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000033:anatomy & histology*; D007422:Intestines / Q000166:cytology* / Q000502:physiology; D053613:Janus Kinase 1 / Q000378:metabolism; D050791:STAT Transcription Factors / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*; D051155:Wnt1 Protein / Q000378:metabolism
D029721:Drosophila Proteins; D050791:STAT Transcription Factors; D051155:Wnt1 Protein; C074622:wg protein, Drosophila; D053613:Janus Kinase 1