title: Stevens-Johnson syndrome: a case report.
abstract: Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal anti-inflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one such potentially lethal adverse drug reaction. Most reported cases of analgesic-induced Stevens-Johnson syndrome were due to oxicams or propionic acid derivatives. There are very few detailed reports of Stevens-Johnson syndrome due to use of diclofenac. We report here a case of Stevens-Johnson syndrome which occurred due to use of diclofenac sodium. The clinical features of this condition and multidisciplinary management of the patient are described in brief.
authors.affiliation: Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India. drshishirshettyomr@yahoo.com
authors.forename: Shishir R
authors.initials: SR
authors.lastname: Shetty
authors.forename: Laxmikanth
authors.initials: L
authors.lastname: Chatra
authors.forename: Prashanth
authors.initials: P
authors.lastname: Shenai
authors.forename: Prasanna K
authors.initials: PK
authors.lastname: Rao
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003229:Conjunctival Diseases / Q000139:chemically induced; D003731:Dental Caries / Q000628:therapy; D004008:Diclofenac / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007871:Leg Ulcer / Q000139:chemically induced; D008875:Middle Aged; D019226:Oral Ulcer / Q000139:chemically induced; D010149:Postoperative Pain / Q000188:drug therapy; D012883:Skin Ulcer / Q000139:chemically induced; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced*; D014081:Tooth Extraction; D014456:Ulcer / Q000139:chemically induced
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac