title: [Case of Fisher syndrome with ocular flutter].
abstract: We report a case of Fisher syndrome accompanied by ocular flutter. A 19-year-old man presented with diplopia and vertigo, associated with preceding symptoms of common cold. Since symmetric weakness of abduction in both eyes, truncal ataxia, diminution of tendon reflexes, and gaze nystagmus were noted, he was diagnosed as having Fisher syndrome. Ocular flutter also was noticed during horizontal gaze. Serum anti-GQ1b antibody and anti-GM1 antibody were detected. He was followed without therapy and the symptoms resolved. The accompanying ocular flutter may suggest that a central nervous system disorder may also be present in Fisher syndrome.
authors.affiliation: Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Ooyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan. nakayasu@med.nihon-u.ac.jp
authors.forename: Koki
authors.initials: K
authors.lastname: Nakayasu
authors.forename: Tohru
authors.initials: T
authors.lastname: Sakimoto
authors.forename: Masayuki
authors.initials: M
authors.lastname: Minami
authors.forename: Syuntaro
authors.initials: S
authors.lastname: Shigihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishikawa
mesh_terms: D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002493:Central Nervous System Diseases / Q000150:complications*; D005677:G(M1) Ganglioside / Q000276:immunology; D005732:Gangliosides / Q000276:immunology; D006801:Humans; D008297:Male; D019846:Miller Fisher Syndrome / Q000175:diagnosis / Q000209:etiology*; D015835:Ocular Motility Disorders / Q000175:diagnosis / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000150:complications; D055815:Young Adult
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D005732:Gangliosides; D005677:G(M1) Ganglioside; C039129:GQ1b ganglioside