title: Combining host-guest systems with nonfouling material for the fabrication of a biosurface: toward nearly complete and reversible resistance of cytochrome c.
abstract: In this letter, a pH-responsive reactivated biointerface is fabricated using an inclusion reaction between an azobenzene-containing self-assembled monolayer and pH-responsive poly(ethylene glycol)-block-poly(acrylic acid) grafted with cyclodextrins. The pH-responsive interface can be switched between an extended state and a relaxed state for the reversible resistance of cytochrome c adsorption completely in cooperation with protein-resistant poly(ethylene glycol).
authors.affiliation: Key Lab of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, PR China.
authors.forename: Pengbo
authors.initials: P
authors.lastname: Wan
authors.forename: Yueyue
authors.initials: Y
authors.lastname: Chen
authors.forename: Yibo
authors.initials: Y
authors.lastname: Xing
authors.forename: Lifeng
authors.initials: L
authors.lastname: Chi
authors.forename: Xi
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry; D045304:Cytochromes c / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008954:Models, Biological; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D000179:Acrylates; D001391:Azo Compounds; D011108:Polymers; D011092:Polyethylene Glycols; D045304:Cytochromes c; C009850:azobenzene