title: A double-blind controlled trial of polyglytone 6211 versus poliglecaprone 25 for use in body contouring.
abstract: The use of absorbable sutures to obtain secure dermal closure in surgeries such as body contouring is common. The risk of complications based on the absorption rate of these materials is unknown. This study attempts to determine whether a faster absorbing suture material such as polyglytone 6211 will lead to fewer complications such as extrusion and granuloma formation as compared with less rapidly absorbing materials such as poliglecaprone 25. Concomitantly, this study also attempts to explore the possible negative outcomes that may be due to faster loss of strength, such as dehiscence and poor scar aesthetics. We found that extrusion occurs less frequently with the rapidly absorbed polyglytone 6211 suture material, without increase in granuloma formation, infection, dehiscence, cellulitis, necrosis, seroma formation, and hematoma formation. We also observed no clinical difference in the cosmetic appearance of scars at the 12-week postoperative follow-up visit.
authors.affiliation: University of Pittsburgh Medical Center, PA, USA.
authors.forename: Nima
authors.initials: N
authors.lastname: Naghshineh
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Ota
authors.forename: Lawton
authors.initials: L
authors.lastname: Tang
authors.forename: James
authors.initials: J
authors.lastname: O'Toole
authors.forename: J Peter
authors.initials: JP
authors.lastname: Rubin
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques; D004146:Dioxanes / Q000627:therapeutic use*; D004311:Double-Blind Method; D004954:Esthetics; D005260:Female; D006801:Humans; D008297:Male; D011091:Polyesters / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D011446:Prospective Studies; D012307:Risk Factors; D013537:Sutures; D016896:Treatment Outcome
chemical_list: D004146:Dioxanes; D011091:Polyesters; C508421:polyglytone 6211; C095495:glycolide E-caprolactone copolymer