Study on the oxidation form of adenine in phosphate buffer solution.
The oxidation of adenine in phosphate buffer solution is investigated using square-wave voltammetry and in situ UV spectroelectrochemistry. The geometry of adenine and the derivatives optimized at DFTB3LYP-6-31G (d, p)-PCM level is in agreement with the crystal structure, and the imitated UV spectra of adenine and the product at electrode are consistent with the in situ UV spectra. The relationship between the electrochemical property and the molecular structure is also discussed. The experimental and theoretical results show that the adenine oxidation origins from the neutral adenine.
Song
Yuan-Zhi
YZ
Jiangsu Province Key Laboratory for Chemistry of Low-Dimensional Materials, School of Chemistry & Chemical Engineering, Huaiyin Normal University, Huai An 223300, People's Republic of China. songyuanzhi@126.com
Zhou
Jian-Feng
JF
Zhu
Feng-Xia
FX
Ye
Yong
Y
Xie
Ji-Min
JM
D000225:Adenine / Q000737:chemistry*; D002021:Buffers; D055664:Electrochemical Techniques; D016011:Normal Distribution; D010084:Oxidation-Reduction; D010710:Phosphates / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D002021:Buffers; D010710:Phosphates; D000225:Adenine; C018279:sodium phosphate