Oncometabolite? IDH1 discoveries raise possibility of new metabolism targets in brain cancers and leukemia.
Garber
Ken
K
D015971:Gene Expression Regulation, Enzymologic; D015972:Gene Expression Regulation, Neoplastic; D016147:Genes, Tumor Suppressor; D005909:Glioblastoma / Q000378:metabolism; D005977:Glutarates / Q000378:metabolism*; D006019:Glycolysis; D056466:Histone Demethylases / Q000378:metabolism; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D008928:Mitochondria / Q000378:metabolism; D009154:Mutation; D009369:Neoplasms / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D009857:Oncogenes
D005977:Glutarates; C019417:alpha-hydroxyglutarate; C538784:IDH2 protein, human; D007521:Isocitrate Dehydrogenase; C543588:IDH1 protein, human; D056466:Histone Demethylases