title: Chronic, painful lower extremity wounds: postoperative pain management through the use of continuous infusion of regional anaesthesia supplied by a portable pump device.
abstract: Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia directly to the site of interest. A considerable amount of attention in literature has been dedicated to using regional anaesthesia postoperatively for various surgical applications. However, to our knowledge, little or no work has been published concerning the use of infusion of regional anaesthesia in the treatment of painful lower extremity wounds. We present a case report of a 55-year-old gentleman with a complex past medical history, 2-year history of opioid dependency and a 2-week history of intractable pain associated with the combination of debilitating painful diabetic neuropathy and painful lower extremity wounds. After surgical debridement of the lower extremity wounds, substantial analgesia was achieved postoperatively through the implantation of a portable direct infusion pump device. The device supplied 2 ml/hour of 0.25% bupivacaine and resulted in a reduction in pain within the first hour of implantation. Although the device achieved maximal analgesia at 6 hours, we found that this could have been likely reduced through the use of a 5-ml bolus dose of 0.25% bupivacaine at the time of implantation. The device provided sufficient analgesia to the patient without any observed adverse effects, and showed significant potential in avoiding an increase in his requirement for other systemic analgesia including opioids.
authors.affiliation: Southern Arizona Limb Salvage Alliance (SALSA), Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85741, USA.
authors.forename: Christy L
authors.initials: CL
authors.lastname: Scimeca
authors.forename: Timothy K
authors.initials: TK
authors.lastname: Fisher
authors.forename: Manish
authors.initials: M
authors.lastname: Bharara
authors.forename: David G
authors.initials: DG
authors.lastname: Armstrong
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000772:Anesthesia, Local / Q000295:instrumentation / Q000379:methods*; D002045:Bupivacaine / Q000627:therapeutic use; D003646:Debridement / Q000009:adverse effects; D017719:Diabetic Foot / Q000150:complications / Q000601:surgery*; D006801:Humans; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010148:Intractable Pain / Q000209:etiology; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D011182:Postoperative Care / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D002045:Bupivacaine