title: A database analysis of cutaneous lupus erythematosus with the EUSCLE Core Set Questionnaire.
abstract: The aim of this study was to determine whether the Core Set Questionnaire developed recently by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) is a useful tool to evaluate clinical features and therapeutic strategies in cutaneous lupus erythematosus. Disease characteristics were analysed in 50 patients with different subtypes of cutaneous lupus erythematosus from two European centres (Germany and Sweden). Mean age at onset of disease was 42.0 +/- 13.3 years (range: 7-69 years) and this differed significantly between the cutaneous lupus erythematosus subtypes. Moreover, 22 (44.0%) of the patients with cutaneous lupus erythematosus fulfilled four or more of the American College of Rheumatology (ACR) criteria; however, only 7 (14.0%) had severe systemic organ manifestations, such as kidney involvement. The analysis of serological features, such as antinuclear antibodies, revealed further significant differences between the cutaneous lupus erythematosus subtypes. In conclusion, the EUSCLE Core Set Questionnaire provides a useful tool for standardized collection and statistical analysis of data on cutaneous lupus erythematosus in clinical practice.
authors.affiliation: Department of Dermatology, University of Muenster, Muenster, Germany.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Meuth
authors.forename: Suzanne
authors.initials: S
authors.lastname: Amler
authors.forename: Merle
authors.initials: M
authors.lastname: Haust
authors.forename: Dennis
authors.initials: D
authors.lastname: Bein
authors.forename: Cristina
authors.initials: C
authors.lastname: Sauerland
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Köpcke
authors.forename: Gisela
authors.initials: G
authors.lastname: Bonsmann
authors.forename: Filippa
authors.initials: F
authors.lastname: Nyberg
authors.forename: Annegret
authors.initials: A
authors.lastname: Kuhn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D019992:Databases as Topic; D005240:Feasibility Studies; D005260:Female; D005858:Germany; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013548:Sweden; D016896:Treatment Outcome; D055815:Young Adult