Mechanisms of stationary-phase mutagenesis in bacteria: mutational processes in pseudomonads.
In a growth-restricting environment, mutants arise that are able to take over bacterial populations by a process known as adaptive mutation or stationary-phase mutation. This process is best studied in Escherichia coli. The genus Pseudomonas represents one of the largest groups of bacteria able to colonize multiple habitats and to adapt rapidly to new environments. The majority of bacteria including pseudomonads contain a different set of DNA polymerases and DNA repair enzymes than those identified in E. coli. The aim of this review is to provide an overview of the results of studies of mutagenic processes in pseudomonads and to discuss these results in the light of the mechanisms of stationary-phase mutagenesis discovered in E. coli.
Kivisaar
Maia
M
Department of Genetics, Estonian Biocentre, Institute of Molecular and Cell Biology, Tartu University, Tartu, Estonia. maiak@ebc.ee
D001419:Bacteria / Q000235:genetics* / Q000254:growth & development; D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development; D016296:Mutagenesis; D009154:Mutation; D011549:Pseudomonas / Q000235:genetics* / Q000254:growth & development