Cardiac resynchronization therapy in patients with minimally symptomatic heart failure.
Cardiac resynchronization therapy improves mortality and heart failure symptoms in patients with sinus rhythm, depressed left ventricular ejection fraction, a wide QRS complex and moderate-to-severe heart failure symptoms. The results of recent trials suggest that in similar patients with minimal heart failure symptoms cardiac resynchronization therapy is associated with left ventricular reverse remodeling, and may prevent the progression of heart failure.
Venkataraman
Ganesh
G
Washington Electrophysiology and Cardiovascular Research Institute, 106 Irving Street, NW, #204, Washington, DC 20010-2975, USA.
Strickberger
S Adam
SA
D002304:Cardiac Pacing, Artificial; D018450:Disease Progression; D004562:Electrocardiography; D055724:Electrophysiological Phenomena; D006333:Heart Failure / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy*; D006339:Heart Rate; D006352:Heart Ventricles; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D012849:Sinoatrial Node / Q000503:physiopathology; D013318:Stroke Volume; D020257:Ventricular Remodeling