title: Laparoscopic versus open appendectomy in complicated appendicitis: a review of the NSQIP database.
abstract: BACKGROUND
  Laparoscopic appendectomy (LA) has been an established treatment method for uncomplicated acute appendicitis. Controversy still exits regarding the superiority of either laparoscopic or open technique for the treatment of complicated appendicitis.
  
  
  OBJECTIVE
  To examine for benefits in postoperative morbidity comparing laparoscopic versus open appendectomy for complicated appendicitis.
  
  
  METHODS
  A retrospective analysis was performed using the American College of Surgeon's National Surgical Quality Improvement Project (ACS-NSQIP) dataset between 2005 and 2007. Inclusion criteria were patients undergoing either open or laparoscopic appendectomy, and had complicated appendicitis. Patients with negative appendectomies and age less than 18 y old were excluded. The primary outcome variable was postoperative complications. Multivariate analysis was performed adjusting for demographics and standard NSQIP comorbidities.
  
  
  RESULTS
  We identified 2,790 complicated appendicitis cases treated with laparoscopic or open appendectomy. The majority were male (56.6%), White (70.3%), and 39.1% were younger than 40 y of age. On unadjusted analyses, the mean length of stay was significantly shorter for LA cases (3.97 d) than OA cases (5.13 d) (P < 0.001). On multivariate analysis, superficial surgical site infection was 70% less likely to occur in LA (OR 0.304 P = 0.000), organ space infection was 2-fold more likely to occur in LA (OR 2.19 P = 0.003), and dehiscence was 78% less likely to occur in LA (OR 0.22 P = 0.015).
  
  
  CONCLUSIONS
  In cases of complicated appendicitis, laparoscopic appendectomy is superior in terms of superficial and deep wound infections; however, it is associated with an increased incidence of postoperative intra-abdominal abscess.
authors.affiliation: Howard University Hospital, Division of Minimally Invasive and Bariatric Surgery, Washington, DC 20060, USA.
authors.forename: Karleena Regina-Marie
authors.initials: KR
authors.lastname: Tuggle
authors.forename: Gezzer
authors.initials: G
authors.lastname: Ortega
authors.forename: Oluwaseyi B
authors.initials: OB
authors.lastname: Bolorunduro
authors.forename: Tolulope A
authors.initials: TA
authors.lastname: Oyetunji
authors.forename: Richard
authors.initials: R
authors.lastname: Alexander
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Turner
authors.forename: David C
authors.initials: DC
authors.lastname: Chang
authors.forename: Edward E
authors.initials: EE
authors.lastname: Cornwell
authors.forename: Terrence M
authors.initials: TM
authors.lastname: Fullum
mesh_terms: D000328:Adult; D000368:Aged; D001062:Appendectomy / Q000009:adverse effects*; D001064:Appendicitis / Q000601:surgery*; D015992:Body Mass Index; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015994:Incidence; D010535:Laparoscopy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies