title: Unexplained vision loss following removal of epiretinal membrane.
abstract: OBJECTIVE
  To report unexplained severe central vision loss accompanied by a dense central scotoma as an uncommon complication following epiretinal membrane removal.
  
  
  METHODS
  Retrospective, multicentred, case series.
  
  
  RESULTS
  Six patients underwent uncomplicated vitrectomy surgery between 2000 and 2007 at four separate retina practices for removal of an epiretinal membrane. Preoperative vision ranged from 20/60 to 20/100, with a median of 20/70. On the first day postoperatively, all patients noted decreased vision ranging from counting fingers to light perception and were found to have a dense central scotoma. Posterior segment examination revealed a white, oedematous macula in all affected eyes. Vision improved minimally during the follow-up period, which ranged from 2 months to 5 years. The final vision ranged from 20/200 to hand movements. No anatomic or physiologic cause for the decreased vision and central scotoma was identified.
  
  
  CONCLUSIONS
  While uncommon, severe, permanent, central vision loss accompanied by a dense central scotoma can occur following epiretinal membrane removal and should be considered when assessing the risks and benefits of such surgery.
authors.affiliation: The San Francisco Retina Foundation, San Francisco, California, USA.
authors.forename: R H
authors.initials: RH
authors.lastname: Roe
authors.forename: H R
authors.initials: HR
authors.lastname: McDonald
authors.forename: A D
authors.initials: AD
authors.lastname: Fu
authors.forename: J M
authors.initials: JM
authors.lastname: Lahey
authors.forename: R T
authors.initials: RT
authors.lastname: Wendel
authors.forename: J A
authors.initials: JA
authors.lastname: Pearlman
authors.forename: P M
authors.initials: PM
authors.lastname: Monahan
authors.forename: J M
authors.initials: JM
authors.lastname: Jumper
authors.forename: R N
authors.initials: RN
authors.lastname: Johnson
authors.forename: E
authors.initials: E
authors.lastname: Ai
authors.forename: E T
authors.initials: ET
authors.lastname: Cunningham
mesh_terms: D000368:Aged; D001766:Blindness / Q000209:etiology*; D019773:Epiretinal Membrane / Q000601:surgery*; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012607:Scotoma / Q000209:etiology; D014821:Vitrectomy / Q000009:adverse effects*