[Comparison of flavonoids content in huangqi gnizhi wuwu tang of different dosages by uniform design method].
OBJECTIVE
To determine the content of flavonoids in huangqi guizhi wuwu tang (HQGZWWT) of different dosages by uniform design method and analyze their difference for clinical application.


METHODS
The uniform design set five factors and 11 levels to explore the content of flavonoids. The results were analyzed by computer with the method of multiple regression analysis.


RESULTS
The contribution of each medicinal material to the content of total flavonoids was Radix Astragali (51.8%), Rhizoma Zingiberis (0.967%), Rhizoma Zingiberis (0.689%), Ramulus Cinnamomi (0.381%) and Raidix Paenoiae alba (0.185%), respectively.


CONCLUSIONS
The extraction rate of flavonoids is not directly relative to the total amount of medicines, instead, there is an optimum dosage matching for it.
Bian
Hong-rong
HR
Lou
Gui-qin
GQ
Zhang
Qing-bo
QB
Zhao
Zi-jia
ZJ
Li
Yan
Y
D027883:Astragalus Plant / Q000737:chemistry*; D027424:Cinnamomum / Q000737:chemistry*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis*; D029596:Paeonia / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012044:Regression Analysis; D013056:Spectrophotometry, Ultraviolet; D013678:Technology, Pharmaceutical / Q000379:methods
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005419:Flavonoids