title: Design, synthesis and DNA/RNA binding studies of nucleic acids comprising stereoregular and acyclic polycarbamate backbone: polycarbamate nucleic acids (PCNA).
abstract: The designed, chiral, acyclic polycarbamate nucleic acids (PCNA) exhibited sequence and orientation specific binding to nucleic acids. Complexes of PCNA with DNA were as stable as PNA:DNA complexes and those with RNA were as stable as natural DNA:RNA complexes.
authors.affiliation: Division of Organic Chemistry, National Chemical Laboratory, Pune 411008, India.
authors.forename: Vangala
authors.initials: V
authors.lastname: Madhuri
authors.forename: Vaijayanti A
authors.initials: VA
authors.lastname: Kumar
mesh_terms: D002219:Carbamates / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D015394:Molecular Structure; D012313:RNA / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D002219:Carbamates; D012313:RNA; D004247:DNA