Onset of lichen planus during treatment with etanercept.
The case is presented of a 24-year-old Caucasian man with moderate to severe psoriasis vulgaris resistant to traditional topical and systemic treatments who developed lichen planus (LP) during treatment with etanercept. Etanercept was effective, but LP developed after 8 months' therapy. Although LP was deemed possibly related to etanercept therapy, the treatment was not discontinued and topical corticosteroids were applied with some clinical improvement. This is the second report of LP associated with etanercept treatment.
Musumeci
Maria Letizia
ML
Dermatology Clinic, University of Catania, Italy.
Lacarrubba
Francesco
F
Micali
Giuseppe
G
D003875:Drug Eruptions / Q000209:etiology; D000068800:Etanercept; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects* / Q000627:therapeutic use; D007155:Immunologic Factors / Q000009:adverse effects* / Q000627:therapeutic use; D008010:Lichen Planus / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D011565:Psoriasis / Q000188:drug therapy; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use; D012720:Severity of Illness Index; D055815:Young Adult
D005938:Glucocorticoids; D007074:Immunoglobulin G; D007155:Immunologic Factors; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept