title: Higher birth rate after recombinant hCG triggering compared with urinary-derived hCG in single-blastocyst IVF antagonist cycles: a randomized controlled trial.
abstract: In a prospective randomized controlled trial, 119 patients were randomized to receive either recombinant hCG (250 μg) or urinary-derived hCG (10,000 IU) for final oocyte maturation in an antagonist protocol with a fixed dose of recombinant FSH (187.5 IU) and predefined single blastocyst transfer. The delivery rate was improved in the recombinant hCG group compared with the urinary-derived hCG group (44.1 vs. 25.7, respectively); however, adequately powered randomized controlled trials are justified to ascertain whether this difference is true.
authors.affiliation: Center for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium. papanikolaou@irg.gr
authors.forename: Evangelos G
authors.initials: EG
authors.lastname: Papanikolaou
authors.forename: Human
authors.initials: H
authors.lastname: Fatemi
authors.forename: Michel
authors.initials: M
authors.lastname: Camus
authors.forename: Dimitra
authors.initials: D
authors.lastname: Kyrou
authors.forename: Nikos P
authors.initials: NP
authors.lastname: Polyzos
authors.forename: Peter
authors.initials: P
authors.lastname: Humaidan
authors.forename: Basil
authors.initials: B
authors.lastname: Tarlatzis
authors.forename: Paul
authors.initials: P
authors.lastname: Devroey
authors.forename: Herman
authors.initials: H
authors.lastname: Tournaye
mesh_terms: D000328:Adult; D001723:Birth Rate; D006063:Chorionic Gonadotropin / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use* / Q000652:urine; D004334:Drug Administration Schedule; D005260:Female; D005300:Fertility Agents, Female / Q000008:administration & dosage / Q000627:therapeutic use; D005307:Fertilization in Vitro / Q000379:methods*; D006727:Hormone Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008596:Menotropins / Q000008:administration & dosage / Q000627:therapeutic use*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D056826:Single Embryo Transfer / Q000379:methods
chemical_list: D006063:Chorionic Gonadotropin; D005300:Fertility Agents, Female; D006727:Hormone Antagonists; D011994:Recombinant Proteins; D008596:Menotropins