title: Virilizing adrenocortical oncocytoma in a child: a case report.
abstract: Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40-60 yr of age. To our knowledge, only 2 cases of functioning adrenocortical oncocytomas have been reported in childhood. We report a case of functioning adrenocortical oncocytoma in a 14-yr-old female child presenting with virilization. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosterone sulfate. She had an adrenalectomy. The completely resected tumor composed predominantly of oncocytes without atypical mitosis and necrosis. A discussion of this case and a review of the literature on this entity are presented.
authors.affiliation: Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Yeon-Jung
authors.initials: YJ
authors.lastname: Lim
authors.forename: Se-Min
authors.initials: SM
authors.lastname: Lee
authors.forename: Jae-Hun
authors.initials: JH
authors.lastname: Shin
authors.forename: Hyun-Chul
authors.initials: HC
authors.lastname: Koh
authors.forename: Young-Ho
authors.initials: YH
authors.lastname: Lee
mesh_terms: D018249:Adenoma, Oxyphilic / Q000150:complications* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014770:Virilism / Q000209:etiology* / Q000473:pathology / Q000601:surgery