The synthesis of androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta.
Androstane brassinosteroid analogues with alpha-azido acid ester groups in position 17beta were synthesized from 2alpha,3alpha,17beta-trihydroxy-5alpha-androstan-6-one after the protection of the 2alpha,3alpha-diols upon treatment with the corresponding alpha-azido acid and the subsequent deprotection of the diol grouping. Six new castasterone analogues were prepared. The biological activities were evaluated in two bioassays: a rice lamina inclination test and bean second internode bioassays. The activities of the new analogues differ in these two bioassays.
Hnilickova
Jaroslava
J
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
Kohout
Ladislav
L
Capdevila
Enric
E
Esteve
Ana
A
Vilaplana
Marc
M
Molist
Meritxell
M
Brosa
Carme
C
Swaczynova-Oklestkova
Jana
J
Slavikova
Barbora
B
D000731:Androstanes / Q000138:chemical synthesis* / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D004952:Esters; D006878:Hydroxides / Q000737:chemistry
D000731:Androstanes; D001386:Azides; D004952:Esters; D006878:Hydroxides; C031356:hydroxide ion; C033936:androstane