title: Analysis of placental vascularization by means of 3D Power Doppler in women pregnant following oocyte donation.
abstract: OBJECTIVE
  To analyze the differences in placental perfusion in pregnancies following oocyte donation compared to spontaneous pregnancies.
  
  
  METHODS
  A total of 33 patients who became pregnant after oocyte donation are studied and compared to 42 spontaneously pregnant participants. A 3-dimensional Power Doppler is used to obtain 3 placental volumes. Of each volume, 3 portions are analyzed in the form of a spherical ''placental biopsy.'' Four vascularization rates are applied, using the virtual organ computer-aided analysis (VOCAL) method: grey index (GI), vascularization index (VI), flow index (FI), and vascularization-flow index (VFI).
  
  
  RESULTS
  Vascular alterations are demonstrated, manifested by a lower IG and a significantly higher IV in the group of spontaneous pregnancies (GI P = .001; (VI) P = .039) and is almost statistically significant in comparison to the IVF (P = .051).
  
  
  CONCLUSIONS
  Placental perfusion in pregnancies obtained following oocyte donation is deficient in comparison to spontaneous pregnancies.
authors.affiliation: Bernabeu Institute of Fertility and Gynecology, Alicante, Spain. fsellersl@sego.es
authors.forename: F
authors.initials: F
authors.lastname: Sellers López
authors.forename: Domingo
authors.initials: D
authors.lastname: Orozco-Beltran
authors.forename: Vicente
authors.initials: V
authors.lastname: Gil-Guillen
authors.forename: J M
authors.initials: JM
authors.lastname: Lozano
authors.forename: A
authors.initials: A
authors.lastname: Palacios
authors.forename: R
authors.initials: R
authors.lastname: Bernabeu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008875:Middle Aged; D018587:Oocyte Donation / Q000009:adverse effects*; D010920:Placenta / Q000098:blood supply* / Q000000981:diagnostic imaging*; D021041:Placental Circulation; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal / Q000379:methods*