title: First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces.
abstract: A multidrug resistance gene, cfr, and a phenicol resistance gene, fexA, were detected in a Bacillus strain, BS-01, isolated from swine feces. The cfr gene was carried on a novel 16.5-kb plasmid, designated pBS-01. A complete Tn917 structure, which harbors the macrolide-lincosamide-streptogramin B resistance gene erm(B), was located downstream of the cfr gene. The fexA gene was discovered in the chromosomal DNA of the BS-01 strain and identified in a Tn558 variant.
authors.affiliation: Key Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Dai
authors.forename: Cong-Ming
authors.initials: CM
authors.lastname: Wu
authors.forename: Ming-Gui
authors.initials: MG
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Si-Yang
authors.initials: SY
authors.lastname: Huang
authors.forename: Li-Ning
authors.initials: LN
authors.lastname: Xia
authors.forename: Bei-Bei
authors.initials: BB
authors.lastname: Li
authors.forename: Jian-Zhong
authors.initials: JZ
authors.lastname: Shen
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001407:Bacillus / Q000187:drug effects* / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D005243:Feces / Q000382:microbiology*; D055231:Lincosamides / Q000494:pharmacology; D018942:Macrolides / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D025381:Streptogramin B / Q000494:pharmacology; D013552:Swine
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D055231:Lincosamides; D018942:Macrolides; D025381:Streptogramin B