Acute hepatitis and personality change in a 31-year-old man taking prohormone supplement SUS500.
BACKGROUND
For decades, anabolic-androgenic steroids have been abused to enhance muscle growth. The harm inflicted by these compounds is well documented.


OBJECTIVE
The authors investigated and report on a case in which a male patient self-prescribed some newer dietary supplements, about which less is known.


METHODS
The authors report on a case of hepatitis and aggressive personality changes in a 31-year-old man taking purported prohormone agent SUS500 and other, newer supplements.


RESULTS
Diagnosis was based on history, mental status exam, and laboratory findings. With discontinuation of all supplements and supportive care, the patient's personality changes resolved, and normal liver function returned.


CONCLUSIONS
The authors conclude that newer anabolic supplements may cause some of the same side effects as traditional steroid hormones.
Wingert
Nathaniel
N
Dept. of Psychiatry, Naval Medical Center, Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA.
Tavakoli
Hamid
H
Yoder
Elizabeth
E
D000111:Acetylcysteine / Q000008:administration & dosage; D000208:Acute Disease; D000328:Adult; D000374:Aggression / Q000187:drug effects; D045930:Anabolic Agents / Q000506:poisoning*; D000728:Androgens / Q000506:poisoning*; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D019587:Dietary Supplements; D004300:Doping in Sports / Q000379:methods / Q000523:psychology; D005221:Fatigue / Q000150:complications; D005492:Folic Acid / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects; D008297:Male; D018908:Muscle Weakness / Q000150:complications; D010551:Personality / Q000187:drug effects*; D010554:Personality Disorders / Q000139:chemically induced* / Q000628:therapy; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced / Q000150:complications; D013256:Steroids / Q000009:adverse effects; D013831:Thiamine / Q000008:administration & dosage; D014891:Weight Lifting
D045930:Anabolic Agents; D000728:Androgens; D013256:Steroids; D005492:Folic Acid; D000111:Acetylcysteine; D013831:Thiamine