title: Catalytic enantioselective synthesis of sterically demanding alcohols using di(2 degrees -alkyl)zinc prepared by the refined Charette's method.
abstract: A highly practical, catalytic enantioselective 2 degrees -alkyl addition to aldehydes and ketones was developed. Chiral phosphoramide ligand (1) with salt-free and solvent-free di(2 degrees -alkyl)zinc reagents prepared from (2 degrees -alkyl)MgCl was essential.
authors.affiliation: Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa, Nagoya, 464-8603, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Hatano
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Mizuno
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Ishihara