Tropheryma whipplei in the skin of patients with classic Whipple's disease.
Positive Tropheryma whipplei PCR results in skin biopsies were frequent in patients with classic Whipple's disease without skin manifestations. The bacterium was alive, as a strain was successfully cultured. The skin may be a reservoir for T. whipplei and may be helpful in the non-invasive diagnosis of the disease.
Angelakis
Emmanouil
E
Université de la Méditerranée, Unité des Rickettsies, URMITE CNRS-IRD UMR 6236, Faculté de Médecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France.
Fenollar
Florence
F
Lepidi
Hubert
H
Birg
Marie-Laure
ML
Raoult
Didier
D
D006801:Humans; D007150:Immunohistochemistry; D016133:Polymerase Chain Reaction; D012867:Skin / Q000382:microbiology*; D054851:Tropheryma / Q000235:genetics / Q000302:isolation & purification*; D008061:Whipple Disease / Q000382:microbiology*