title: [Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma].
abstract: Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time. Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postinterventional angiography showed complete occlusion of all supporting blood vessels. Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications. Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications. It could represent a new strategy for the treatment of JNA, as is already the case with other highly vascularized head and neck tumors. Moreover, it increases the likelihood of achieving complete resection.
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie, Klinikum Bielefeld, Teutoburger Strasse 50, 33604, Bielefeld, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Lehmann
authors.forename: S
authors.initials: S
authors.lastname: Ulrich
authors.forename: U
authors.initials: U
authors.lastname: Reineke
authors.forename: U
authors.initials: U
authors.lastname: Hamberger
authors.forename: U
authors.initials: U
authors.lastname: Dietrich
authors.forename: H
authors.initials: H
authors.lastname: Sudhoff
mesh_terms: D000293:Adolescent; D018322:Angiofibroma / Q000098:blood supply* / Q000175:diagnosis / Q000601:surgery*; D000792:Angiography; D004121:Dimethyl Sulfoxide; D004621:Embolization, Therapeutic / Q000379:methods*; D004724:Endoscopy; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000098:blood supply* / Q000175:diagnosis / Q000601:surgery*; D011145:Polyvinyls; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed
chemical_list: C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide