A database analysis of cutaneous lupus erythematosus with the EUSCLE Core Set Questionnaire.
The aim of this study was to determine whether the Core Set Questionnaire developed recently by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) is a useful tool to evaluate clinical features and therapeutic strategies in cutaneous lupus erythematosus. Disease characteristics were analysed in 50 patients with different subtypes of cutaneous lupus erythematosus from two European centres (Germany and Sweden). Mean age at onset of disease was 42.0 +/- 13.3 years (range: 7-69 years) and this differed significantly between the cutaneous lupus erythematosus subtypes. Moreover, 22 (44.0%) of the patients with cutaneous lupus erythematosus fulfilled four or more of the American College of Rheumatology (ACR) criteria; however, only 7 (14.0%) had severe systemic organ manifestations, such as kidney involvement. The analysis of serological features, such as antinuclear antibodies, revealed further significant differences between the cutaneous lupus erythematosus subtypes. In conclusion, the EUSCLE Core Set Questionnaire provides a useful tool for standardized collection and statistical analysis of data on cutaneous lupus erythematosus in clinical practice.
Meuth
Anna Maria
AM
Department of Dermatology, University of Muenster, Muenster, Germany.
Amler
Suzanne
S
Haust
Merle
M
Bein
Dennis
D
Sauerland
Cristina
C
Köpcke
Wolfgang
W
Bonsmann
Gisela
G
Nyberg
Filippa
F
Kuhn
Annegret
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D019992:Databases as Topic; D005240:Feasibility Studies; D005260:Female; D005858:Germany; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013548:Sweden; D016896:Treatment Outcome; D055815:Young Adult