Salivary gland tumor: a review of 599 cases in a Brazilian population.
Salivary gland tumors consist of a group of heterogeneous lesions with complex clinicopathological characteristics and distinct biological behaviors. Worldwide series show a contrast in the relative incidence of salivary gland tumors, with some discrepancies in clinicopathological data. The main aim of this study was to describe demographic characteristics of 599 cases in a population from Central Brazil over a 10-year period and compare these with other epidemiological studies. Benign tumors represented 78.3% of the cases. Women were the most affected (61%) and the male:female ratio was 1:1.6. Parotid gland tumors were the most frequent (68.5% of cases) and patient age ranged from 1 to 88 years-old (median of 45 years old). The most frequent tumors were pleomorphic adenomas (68.4%) and benign tumors were significantly more frequent in the parotid (75.9%), while malignant tumors were more frequent in the minor salivary glands (40%) (P < 0.05). In conclusion, women and the parotid gland were the most affected and pleomorphic adenoma was the most frequent lesion, followed by adenoid cystic carcinoma and Warthin's tumor.
de Oliveira
Flávia Aparecida
FA
Instituto de Patologia Tropical e Saúde Pública of the Universidade Federal de Goiás, Goiânia-GO, Brazil.
Duarte
Eliza Carla Barroso
EC
Taveira
Cláudia Teixeira
CT
Máximo
Aline Abreu
AA
de Aquino
Erica Carvalho
EC
Alencar
Rita de Cássia
Rde C
Vencio
Eneida Franco
EF
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D055815:Young Adult