Controlled synthesis of linear alpha-cyclodextrin oligomers using copper-catalyzed Huisgen 1,3-dipolar cycloaddition.
The design and efficient synthesis of a novel class of linear oligomers based on cyclodextrins are described. These supramolecules have relatively rigid structures with well-defined topology and sizes, which could provide them with the ability to be used as scaffolds to present bioactive molecules to their receptors as well as host molecules.
Rawal
Girish K
GK
Alberta Ingenuity Centre for Carbohydrate Science, Department of Chemistry, University of Calgary, 2500, University Drive NW, Calgary, Alberta T2N 1N4 Canada.
Zhang
Ping
P
Ling
Chang-Chun
CC
D002236:Carbohydrate Conformation; D002384:Catalysis; D019327:Copper Sulfate / Q000737:chemistry*; D003500:Cyclization; D047391:alpha-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry
D047391:alpha-Cyclodextrins; D019327:Copper Sulfate; C032613:alpha-cyclodextrin