title: Esophageal metastasis from occult lung cancer.
abstract: A 66-year-old man with dysphagia was found to have a poorly differentiated esophageal carcinoma by incision biopsy. Following esophagectomy, reconstruction with a gastric tube was performed. Pathological examination and immunohisto-chemistry showed infiltration of adenocarcinoma cells with positive thyroid transcription factor 1-staining in the submucosal layer, which indicated metastatic esophageal carcinoma. Although no pulmonary lesion could be visualized by imaging or bronchoscopy, pulmonary origin was highly suspected as a result of positive thyroid transcription factor 1-staining. To the best of our knowledge, this is the first reported case of metastatic esophageal carcinoma from occult lung cancer (AJCC TNM stage TX).
authors.affiliation: Department of Surgery, Chutung Veterans Hospital, Hsinchu, Taipei, Taiwan, ROC. hsupokuei@yahoo.com.tw
authors.forename: Po-Kuei
authors.initials: PK
authors.lastname: Hsu
authors.forename: Sen-Ei
authors.initials: SE
authors.lastname: Shai
authors.forename: John
authors.initials: J
authors.lastname: Wang
authors.forename: Chung-Ping
authors.initials: CP
authors.lastname: Hsu
mesh_terms: D000368:Aged; D004268:DNA-Binding Proteins / Q000032:analysis; D004938:Esophageal Neoplasms / Q000737:chemistry / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D014157:Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; C504003:TTF1 protein, human; D014157:Transcription Factors