title: Cytoreductive surgery and ovarian carcinoma.
abstract: OBJECTIVE
  the aim of this study is to demonstrate if Cytoreductive surgery in patients with ovarian carcinoma increases overall survival.
  
  
  METHODS
  during the period between 1998 and 2008, 60 patients with a relapse of ovarian cancer, were evaluated in order to undergo a cytoreductive surgery.
  
  
  RESULTS
  an optimal cytoreduction (residual disease < 1 cm maximum diameter) was obtained in over half of patients.
  
  
  CONCLUSIONS
  surgery remains the best therapeutic approach in ovarian cancer since it is associated with an increase in survival in all patients undergoing cytoreduction especially in the advanced stages of the disease. These results and those of other studies allow us to determine which patients may benefit from the cytoreductive surgery, improving their survival rate. A disease-free interval > 12 months is the best predictive factor of improved survival rate after surgery.
authors.affiliation: Department of Obstetrics and Gynecology, Second University of Naples, Naples, Italy. giancarlo.balbi@unina2.it
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Balbi
authors.forename: Antonietta
authors.initials: A
authors.lastname: Monteverde
authors.forename: Isabella
authors.initials: I
authors.lastname: Landino
authors.forename: Maria Amparo
authors.initials: MA
authors.lastname: Manganaro
authors.forename: Ciro
authors.initials: C
authors.lastname: Franzese
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010051:Ovarian Neoplasms / Q000401:mortality / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology