Investigation of the cyanuric acid contamination caused by acetonitrile and alkali detergent for the LC-ESI MS/MS analysis.
During the replicate analysis of melamine and cyanuric acid by LC-ESI MS/MS for the method development, recurring cyanuric acid contamination was observed. The high concentration (6,950 mg/kg) of cyanuric acid was found in the strong alkali detergent used in a glassware washing machine. However, only small concentration of cyanuric acid (0.002-0.004 mg/kg) was detected in the glassware washed with the above alkali detergent. The major contamination source of cyanuric acid was some specific lot of acetonitrile (0.093 mg/kg) that increased the background level of the ion chromatogram.
Kim
Hyun
H
Analysis Team, HAITAI Confectionery & Foods Co. Ltd, Seoul, South Korea.
Roh
Jung Seop
JS
Oh
Chang-Hwan
CH
D000097:Acetonitriles / Q000737:chemistry*; D000468:Alkalies / Q000737:chemistry; D002681:China; D002851:Chromatography, High Pressure Liquid; D003902:Detergents / Q000737:chemistry*; D004784:Environmental Monitoring; D005506:Food Contamination / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014227:Triazines / Q000737:chemistry*
D000097:Acetonitriles; D000468:Alkalies; D003902:Detergents; D014227:Triazines; C004632:cyanuric acid; C032159:acetonitrile