Emergence of VIM-12 in Enterobacter cloacae.
Detection of the bla(VIM-12) gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.
Panopoulou
Maria
M
Laboratory of Clinical Microbiology, School of Medicine, Democritus University of Thrace, Alexandroupolis 68100, Greece.
Alepopoulou
Eleonora
E
Ikonomidis
Alexandros
A
Grapsa
Anastasia
A
Paspalidou
Eleni
E
Kartali-Ktenidou
Sofia
S
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016972:Enterobacter cloacae / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D032023:Integrons; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000032:analysis; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D001618:beta-Lactamases