title: A proposed framework to standardize the neurocognitive assessment of patients with pediatric systemic lupus erythematosus.
abstract: OBJECTIVE
  To develop and propose a standardized battery of neuropsychological tests for the assessment of cognitive functioning of children and adolescents with pediatric systemic lupus erythematosus (SLE).
  
  
  METHODS
  A committee of health care professionals involved in the assessment of pediatric SLE patients reviewed the literature to identify cognitive domains most commonly affected in pediatric SLE and in adult SLE. They then reviewed the standardized tests available for children and adolescents that assess the cognitive domains identified. Through a structured consensus formation process, the committee considered the psychometric characteristics and durations of the tests.
  
  
  RESULTS
  A test battery was developed that appears suitable to provide a comprehensive assessment of cognitive domains commonly affected by pediatric SLE within a 2.5-hour period.
  
  
  CONCLUSIONS
  It is hoped that the consistent use of this reliable and efficient battery increases the practicality of routine evaluations in pediatric SLE, enabling between-cohort comparisons and facilitating the longitudinal assessment of individual patients over time.
authors.affiliation: Weill-Cornell Medical College, New York, New York 10021, USA. gsross@med.cornell.edu
authors.forename: Gail S
authors.initials: GS
authors.lastname: Ross
authors.forename: Frank
authors.initials: F
authors.lastname: Zelko
authors.forename: Marisa
authors.initials: M
authors.lastname: Klein-Gitelman
authors.forename: Deborah M
authors.initials: DM
authors.lastname: Levy
authors.forename: Eyal
authors.initials: E
authors.lastname: Muscal
authors.forename: Laura E
authors.initials: LE
authors.lastname: Schanberg
authors.forename: Kelly
authors.initials: K
authors.lastname: Anthony
authors.forename: Hermine I
authors.initials: HI
authors.lastname: Brunner
mesh_terms: D000293:Adolescent; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000523:psychology*; D009483:Neuropsychological Tests / Q000592:standards*; D012015:Reference Standards