title: Avascular necrosis of the metacarpals in juvenile dermatomyositis.
abstract: Avascular necrosis (AVN) of the metacarpal heads is uncommon and has been associated with trauma, systemic lupus erythematosus, and corticosteroid usage. There have been no previous reports of metacarpal AVN described in patients with juvenile dermatomyositis. Descriptions of AVN in juvenile dermatomyositis are rare. We present 2 cases of patients with juvenile dermatomyositis who developed multifocal avascular necrosis after corticosteroid therapy with unusual distribution and review the literature on metacarpal AVN.
authors.affiliation: Division of Pediatric Rheumatology, Duke University Medical Center, Durham, NC 27710, USA. angela.robinson2@duke.edu
authors.forename: Angela Byun
authors.initials: AB
authors.lastname: Robinson
authors.forename: C Egla
authors.initials: CE
authors.lastname: Rabinovich
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D050279:Metacarpal Bones / Q000473:pathology*; D010020:Osteonecrosis / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones