Incidence and management of high grade glioma in Māori and non-Māori patients.
A retrospective analysis of 301 patients was undertaken between 1993 and 2003 to evaluate the relationship of ethnicity with incidence, treatment and survival in patients undergoing surgery for high grade glioma (HGG) in New Zealand. There was no difference in age standardised incidence of HGG in Māori compared to non-Māori patients; 4.2/100,000 person years (95% confidence interval [CI] 2.6-6.9) versus 4.1 (95% CI 3.6-4.6). Māori were more likely to have complete tumour resection (odds ratio 3.59 (95% CI 1.01-12.76)) but waited 1.32 (95% CI 0.98-1.79) times longer for radiotherapy. Median survival was 29 weeks with poorer survival in Māori compared to non-Māori (hazard ratio 1.55 [95% CI 0.95-2.55]). We concluded that the incidence of HGG in Māori is similar to non-Maori. However, Māori with HGG have higher rates of complete resection but wait longer for radiotherapy and may have poorer overall survival than non-Māori.
Alexander
Hamish
H
Department of Neurosurgery, Wellington Hospital, Capital and Coast District Health Board, Private Bag 7902, Wellington, New Zealand. hamishalexander@gmail.com
Irwin
Chris
C
Purdie
Gordon
G
Hunn
Martin
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000208:ethnology* / Q000401:mortality / Q000628:therapy*; D019468:Disease Management; D005006:Ethnicity / Q000208:ethnology*; D005260:Female; D005910:Glioma / Q000208:ethnology* / Q000401:mortality / Q000628:therapy*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009520:New Zealand / Q000208:ethnology; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D055815:Young Adult