title: Efficacy of dog-appeasing pheromone (DAP) for ameliorating separation-related behavioral signs in hospitalized dogs.
abstract: Dogs hospitalized in veterinary clinics are likely to show signs of separation-induced anxiety from hospitalization. The study assessed the effect of dog-appeasing pheromone (DAP) on 10 typical separation-related behavioral signs in hospitalized dogs. A DAP treated group (n = 24) was compared with a placebo control group (n = 19). There was overall amelioration of the signs without 'vigilance' and 'anorexia' in the DAP-treated dogs; marked decreases were noted in elimination (P = 0.038), excessive licking (P = 0.005), and pacing (P = 0.017). The results suggest that the use of DAP could decrease separation-induced anxiety, distress, and fear in inpatients, and possibly facilitate recovery in hospitalized dogs.
authors.affiliation: Department of Veterinary Physiology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
authors.forename: Young-Mee
authors.initials: YM
authors.lastname: Kim
authors.forename: Jong-Kyung
authors.initials: JK
authors.lastname: Lee
authors.forename: A M
authors.initials: AM
authors.lastname: Abd el-aty
authors.forename: Sung-Hee
authors.initials: SH
authors.lastname: Hwang
authors.forename: Jae-Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Sang-Mok
authors.initials: SM
authors.lastname: Lee
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001010:Anxiety, Separation / Q000188:drug therapy*; D001522:Behavior, Animal / Q000187:drug effects; D004283:Dog Diseases / Q000188:drug therapy* / Q000523:psychology; D004285:Dogs; D004311:Double-Blind Method; D005260:Female; D008297:Male; D010675:Pheromones / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D010675:Pheromones