Copy coats: COPI mimics clathrin and COPII.
The assembly of COPI into a cage-like lattice sculpts membrane vesicles that transport cargo from the Golgi apparatus. Now, Lee and Goldberg (2010) present X-ray crystal structures of COPI suggesting that these coats combine selected features of two other archetypal coats, clathrin and COPII.
Hughson
Frederick M
FM
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. hughson@princeton.edu