Consequences of a network view for genetic association studies.
Cramer et al's proposal to view mental disorders as the outcome of network dynamics among symptoms obviates the need to invoke latent traits to explain co-occurrence of symptoms and syndromes. This commentary considers the consequences of such a network view for genetic association studies.
van der Sluis
Sophie
S
Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije University Amsterdam, 1081 HV Amsterdam, The Netherlands. sophie.van.der.sluis@cncr.vu.nl
Kan
Kees-Jan
KJ
Dolan
Conor V
CV
D056726:Genetic Association Studies; D006801:Humans; D001523:Mental Disorders / Q000235:genetics*; D008960:Models, Psychological