title: Characterization of nanofilm spray products by mass spectrometry.
abstract: The use of nanofilm spray products (NFPs) has been associated with a number of severe cases of airway injuries; however, the causative agents are unknown. To identify possible causative agents, 10 products from three different suppliers have been analysed using two mass spectrometric methods: (1) ESI-MS and ESI-MS/MS; (2) GC-MS and GC-MS/MS. The 10 products could be classified into three groups (NFPs 1-3). NFP 1 and NFP 2 contained hydrolysates and condensates of the organo-functionalized silanes 1H,1H,2H,2H-perfluorooctyl triisopropoxysilane and hexadecyl triethoxysilane, respectively. NFP 3 contained non-ionic detergents and abrasive as active ingredients. To verify the fluorosilane solution in NFP 1, a synthetic NFP 1 was prepared by hydrolysis and condensation of 1H,1H,2H,2H-perfluorooctyl triethoxysilane. After about 1month in acidic 2-propanol substitution of the ethoxy groups with isopropoxy groups had taken place and all silane was converted to disiloxanes, trisiloxanes and tetrasiloxanes.
authors.affiliation: The National Research Centre for the Working Environment, Lersø Parkalle 105, 2100 København Ø, Denmark. awn@nrcwe.dk
authors.forename: Asger W
authors.initials: AW
authors.lastname: Nørgaard
authors.forename: Peder
authors.initials: P
authors.lastname: Wolkoff
authors.forename: Frants R
authors.initials: FR
authors.lastname: Lauritsen
mesh_terms: D000393:Air Pollutants / Q000737:chemistry*; D013058:Mass Spectrometry; D049329:Nanostructures / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry; D012833:Siloxanes / Q000737:chemistry
chemical_list: D000393:Air Pollutants; D012821:Silanes; D012833:Siloxanes