title: Pancreatic endocrine tumor with neoplastic venous thrombus and bilobar liver metastasis. A case report.
abstract: We report the case of an asymptomatic 56-year-old woman with a metastatic pancreatic endocrine tumor, fortuitously discovered by abdominal imaging. A CT-scan showed a large mass in the pancreatic tail invading the spleen and stomach; in addition, there was neoplastic thrombus within the spleno-mesentericoportal venous confluence and bilobar liver metastases. Surgical resection was performed in two stages. The first procedure was an extended left pancreatectomy with venous thrombectomy and "clearance" of the left hepatic lobe. During the interval, embolization of the right portal vein was carried out. Right hepatectomy and radiofrequency destruction of residual metastases was then performed. On the basis of completeness of the resection and the histopathological data, the patient did not undergo any adjuvant therapy, in accordance with French guidelines. At 1 year of follow-up, there was no evidence of recurrence.
authors.affiliation: Service of oncologic and gastrointestinal surgery, centre de lutte contre le cancer, institut Paoli-Calmette, 232, boulevard Sainte-Marguerite, 13009 Marseille, France. louisebarbier@hotmail.fr
authors.forename: L
authors.initials: L
authors.lastname: Barbier
authors.forename: O
authors.initials: O
authors.lastname: Turrini
authors.forename: A
authors.initials: A
authors.lastname: Sarran
authors.forename: J-R
authors.initials: JR
authors.lastname: Delpero
mesh_terms: D017115:Catheter Ablation; D004621:Embolization, Therapeutic; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D018358:Neuroendocrine Tumors / Q000150:complications* / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D011859:Radiography; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000628:therapy