title: Predictors of mortality in patients returning to dialysis after allograft loss.
abstract: BACKGROUND
  Although patients requiring dialysis after graft loss are increasing, data regarding the outcomes of patients on dialysis after graft loss are limited. We investigated the characteristics and risk factors for mortality in patients reinitiating dialysis after graft loss.
  
  
  METHODS
  A retrospective analysis was done for 292 patients who reinitiated dialysis after graft loss between 1985 and 2006.
  
  
  RESULTS
  The mean glomerular filtration rate (GFR) at dialysis reinitiation was 9.1 +/- 4.6 ml/min/1.73 m(2). Cardiovascular disease was the most common cause of death during the 67.4 +/- 50.6 months of follow-up. History of diabetes (HR 4.11, p = 0.02), new-onset diabetes after transplantation (HR 1.96, p = 0.03), Charlson comorbidity index score (HR 1.66, p = 0.03), and low serum albumin levels (HR 0.42, p = 0.03) were independent risk factors for mortality. However, GFR at dialysis reinitiation was not.
  
  
  CONCLUSIONS
  Comorbid conditions, new-onset diabetes after transplantation, and hypoalbuminemia predicted mortality in patients who returned to dialysis after graft failure.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jung Tak
authors.initials: JT
authors.lastname: Park
authors.forename: Tae-Hyun
authors.initials: TH
authors.lastname: Yoo
authors.forename: Tae Ik
authors.initials: TI
authors.lastname: Chang
authors.forename: Joo Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Dong Hyung
authors.initials: DH
authors.lastname: Lee
authors.forename: Beom Seok
authors.initials: BS
authors.lastname: Kim
authors.forename: Shin-Wook
authors.initials: SW
authors.lastname: Kang
authors.forename: Ho Yung
authors.initials: HY
authors.lastname: Lee
authors.forename: Myoung Soo
authors.initials: MS
authors.lastname: Kim
authors.forename: Soon Il
authors.initials: SI
authors.lastname: Kim
authors.forename: Yu Seun
authors.initials: YS
authors.lastname: Kim
authors.forename: Kyu Hun
authors.initials: KH
authors.lastname: Choi
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000150:complications / Q000401:mortality; D002423:Cause of Death; D003920:Diabetes Mellitus / Q000401:mortality; D005260:Female; D006084:Graft Rejection / Q000276:immunology* / Q000401:mortality*; D006085:Graft Survival / Q000276:immunology; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014184:Transplantation, Homologous / Q000276:immunology; D017211:Treatment Failure