Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud.
CONCLUSIONS
We present the first parallel implementation of the T-Coffee consistency-based multiple aligner. We benchmark it on the Amazon Elastic Cloud (EC2) and show that the parallelization procedure is reasonably effective. We also conclude that for a web server with moderate usage (10K hits/month) the cloud provides a cost-effective alternative to in-house deployment.


BACKGROUND
T-Coffee is a freeware open source package available from http://www.tcoffee.org/homepage.html
Di Tommaso
Paolo
P
Centre For Genomic Regulation (Pompeu Fabra University), Carrer del Doctor Aiguader 88, Barcelona, Spain.
Orobitg
Miquel
M
Guirado
Fernando
F
Cores
Fernado
F
Espinosa
Toni
T
Notredame
Cedric
C
D000465:Algorithms; D020407:Internet; D016415:Sequence Alignment / Q000379:methods*; D012984:Software