title: Ectopia cordis in a fetus with mosaic trisomy 16.
abstract: Ectopia cordis and mosaic trisomy 16 are two rare fetal anomalies, which have not been reported in association. We report a case of an isolated ectopia cordis at 11(+3) weeks. Subsequent embryological examination confirmed thoracic ectopia cordis with normal heart structure and array comparative genomic hybridization of fetal tissue detected trisomy 16 mosaicism.
authors.affiliation: Fetal Medicine Unit, 1st Department of Obstetrics & Gynecology, Papageorgiou Hospital, Aristotle University of Thessaloniki, Periferiakos Str., 56429, Thessaloniki, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Arnaoutoglou
authors.forename: Soultana
authors.initials: S
authors.lastname: Meditskou
authors.forename: Anastasia
authors.initials: A
authors.lastname: Keivanidou
authors.forename: Marilena
authors.initials: M
authors.lastname: Manthou
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Anesidis
authors.forename: Efstratios
authors.initials: E
authors.lastname: Assimakopoulos
authors.forename: Apostolos
authors.initials: A
authors.lastname: Athanasiadis
authors.forename: Sailesh
authors.initials: S
authors.lastname: Kumar
mesh_terms: D000025:Abortion, Eugenic; D000328:Adult; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics; D054083:Ectopia Cordis / Q000000981:diagnostic imaging* / Q000235:genetics; D005260:Female; D006801:Humans; D009030:Mosaicism; D011247:Pregnancy; D014314:Trisomy / Q000175:diagnosis / Q000235:genetics; D016216:Ultrasonography, Prenatal / Q000379:methods*; D055815:Young Adult