A case report of complete remission of pulmonary metastases from epithelioid sarcoma to navelbine chemotherapy.
Management of soft tissue sarcomas can be very challenging because they have a high rate of metastasis, especially to the lungs, and respond very poorly to the currently available chemotherapeutic drugs. We present a case of epithelioid sarcoma in which complete remission of pulmonary metastases was observed after treatment with a single agent, navelbine, a vinca alkaloid, and a potential therapeutic agent. The patient has been persistently free of metastases for 4 years since treatment with navelbine. Further studies are warranted to establish the role of navelbine for the treatment of soft tissue sarcoma and their metastases.
Tariq
Zeeshan
Z
Departments of Medicine, University of Toledo, Toledo, OH, USA. zeeshan.tariq@utoledo.edu
Ghose
Abhimanyu
A
Bawany
Muhammad Z
MZ
Saeed
Bilal
B
Mohamed
Iman
I
Harmon
David
D
D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005542:Forearm; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012074:Remission Induction / Q000379:methods; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077235:Vinorelbine
D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D000077235:Vinorelbine