Alpha-glucosidase inhibitory constituents of Linaria kurdica subsp. eriocalyx.
Three known iridoid glycosides, antirrhide (1), antirrhinoside (2), and 5-O-beta-allosylantirrhinoside (3), and two known flavone glycosides, linariin (4"'-O-acetylpectolinarin) (4) and linarin (acacetin-7-O-beta-D-rutinoside) (5) were isolated from Linaria kurdica Boiss & Hohen. subsp. eriocalyx. The structures of the isolated compounds were established from spectroscopic evidence. Compounds 1-3 showed high inhibitory potential against alpha-glucosidase.
Aydoğdu
Irfan
I
Department of Chemistry, Faculty of Science, Ege University, Bornova, Izmir 35100, Turkey.
Zihnioğlu
Figen
F
Karayildirim
Tamer
T
Gülcemal
Derya
D
Alankuş-Calişkan
Ozgen
O
Bedir
Erdal
E
D065089:Glycoside Hydrolase Inhibitors; D039823:Iridoids / Q000737:chemistry* / Q000494:pharmacology*; D032221:Linaria / Q000737:chemistry*; D015394:Molecular Structure
D065089:Glycoside Hydrolase Inhibitors; D039823:Iridoids