[The clinical research of contrast-enhanced sonography in evaluating renal cortical perfusion during follow up of PTRAS].
OBJECTIVE
To investigate the feasibility of contrast-enhanced sonography in the evaluating renal cortical perfusion.


METHODS
Thirteen patients with renal artery stenosis (RAS) >or= 50% were included. Technos Du8 and CnTI technology were used in the pre and post treatment of percutaneous transluminal renal artery angioplasty with stent (PTRAS). Differences in area under curve (AUC) were used to quantitate renal cortex perfusion change during follow up of PTRAS.


RESULTS
Contrast-enhanced sonography showed significantly reduced peak flow rate by improving the renal trunk artery patency with PTRAS. AUC ratio was (6.41 +/- 38.14)% in PTRAS renal vs (-9.65 +/- 24.35)% in contralateral renal during 3 - 6 months follow up (P > 0.05). They had no statistical difference. Otherwise, Severe stenosis of renal artery (>or= 75%) show the decreased AUC ratio of (-5.19 +/- 45.88)% in 7 cases vs (19.95 +/- 23.61)% with midrange stenosis (50% - 75%) in 6 cases (P < 0.05).


CONCLUSIONS
Contrast-enhanced sonography may provide a sensitive detection of change of the renal cortical microcirculation with the helpful to estimate therapeutic effect of PTRAS.
Zhang
Lan
L
Vasculary Department, Renji Hospital, Shanghai Jiaotong University, Shanghai, China.
Liang
Wei
W
Xue
Guan-hua
GH
Ye
Meng
M
Fang
Hua
H
Zhang
Ji-wei
JW
D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D003287:Contrast Media; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply*; D007672:Kidney Cortex / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging*; D014463:Ultrasonography
D003287:Contrast Media