Should all oocyte donors receive prophylactic antibiotics for retrieval?
In a retrospective study comparing 526 oocyte donors who received prophylactic antibiotics for oocyte retrieval with a comparable group of 625 who did not, the incidence of infection after retrieval was reduced from 0.4% to 0 in the group receiving antibiotics. Donors take risks but have no medical indication for the procedures that they undergo; our data suggest that prophylactic antibiotics at retrieval should be considered to minimize the risk of infection.
Weinreb
Elena B
EB
Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10021, USA.
Cholst
Ina N
IN
Ledger
William J
WJ
Danis
Rachel B
RB
Rosenwaks
Zev
Z
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods; D002440:Cefoxitin / Q000008:administration & dosage / Q000627:therapeutic use; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D018587:Oocyte Donation / Q000009:adverse effects / Q000379:methods*; D054315:Oocyte Retrieval / Q000379:methods*; D034161:Pelvic Infection / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects; D012189:Retrospective Studies; D018805:Sepsis / Q000517:prevention & control; D014260:Triclosan / Q000008:administration & dosage / Q000627:therapeutic use; D055815:Young Adult
D000891:Anti-Infective Agents, Local; D002981:Clindamycin; D014260:Triclosan; D002440:Cefoxitin