No interference of the 1,3-β-D-glucan containing nutritional supplement ImunixX with the 1,3-β-D-glucan serum test.
The detection of 1,3-β-D-glucan serum levels may permit establishing the diagnosis of invasive fungal infections more early. We tested in six healthy volunteers whether the intake of a 1,3-β-D-glucan-containing nutritional supplement leads to false-positive 1,3-β-D-glucan levels. All levels were negative, even in two different dosing regimens.
Spriet
Isabel
I
Pharmacy Department, University Hospitals Leuven, Leuven, Belgium. isabel.spriet@uzleuven.be
Desmet
Stephanie
S
Willems
Ludo
L
Lagrou
Katrien
K
D000328:Adult; D004032:Diet / Q000379:methods*; D005189:False Positive Reactions; D005260:Female; D016469:Fungemia / Q000175:diagnosis*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008297:Male; D009172:Mycology / Q000379:methods*; D011509:Proteoglycans; D044967:Serum / Q000737:chemistry*; D047071:beta-Glucans / Q000097:blood*
D011509:Proteoglycans; D047071:beta-Glucans; C010770:polysaccharide-K