title: Overweight men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles.
abstract: OBJECTIVE
  To evaluate if elevated male body mass influences success after assisted reproductive technologies
  
  
  METHODS
  Retrospective study of 290 cycles.
  
  
  RESULTS
  Male body mass index greater than 25.0 kg/m² was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07-0.69] vs. 0.75 [0.38-1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass.
  
  
  CONCLUSIONS
  In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction.
authors.affiliation: Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA. julia.keltz@gmail.com
authors.forename: Julia
authors.initials: J
authors.lastname: Keltz
authors.forename: Athena
authors.initials: A
authors.lastname: Zapantis
authors.forename: Sangita K
authors.initials: SK
authors.lastname: Jindal
authors.forename: Harry J
authors.initials: HJ
authors.lastname: Lieman
authors.forename: Nanette
authors.initials: N
authors.lastname: Santoro
authors.forename: Alex J
authors.initials: AJ
authors.lastname: Polotsky
mesh_terms: D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D016015:Logistic Models; D008297:Male; D009765:Obesity; D016017:Odds Ratio; D050177:Overweight; D011247:Pregnancy; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic