Nanoceria as Antioxidant: Synthesis and Biomedical Applications.
The therapeutic application of nanomaterials has been a focus of numerous studies in the past decade. Due to its unique redox properties, cerium oxide (ceria) is finding widespread use in the treatment of medical disorders caused by the reactive oxygen intermediates (ROI). The radical-scavenging role of ceria nanoparticles (nanoceria) have been established, as well as the autocatalytic ability of nanoceria to regenerate under various environmental conditions. The synthesis of nanoceria in biocompatible media has also been reported along with cell viability in order to determine the potential use of nanoceria in biomedical applications.
Karakoti
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A.S. Karakoti is with the Surface Engineering and Nanotechnology Facility, Advanced Materials Processing and Analysis Center, Department of Mechanical Materials and Aerospace Engineering, University of Central Florida, Orlando, Florida. N.A. Monteiro-Riviere is with the Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, and the Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, Raleigh, North Carolina. R. Aggarwal and R.J. Narayan are with the Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University. J.P. Davis is with the USDA ARS Market Quality and Handling Research Unit, Department of food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina. W.T. Self is with the Department of Molecular Biology and Microbiology, Burnett College of Biomedical Sciences, University of Central Florida. J. McGinnis is with the Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma. S. Seal is with the Surface Engineering and Nanotechnology Facility, Advanced Materials Processing and Analysis Center, Department of Mechanical Materials and Aerospace Engineering, University of Central Florida; and also with the Nanoscience and Technology Center, University of Central Florida. Dr. Narayan can be reached at e-mail: roger_narayan@unc.edu.
Monteiro-Riviere
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Aggarwal
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Davis
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Narayan
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Self
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McGinnis
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Seal
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