title: A case report of complete remission of pulmonary metastases from epithelioid sarcoma to navelbine chemotherapy.
abstract: Management of soft tissue sarcomas can be very challenging because they have a high rate of metastasis, especially to the lungs, and respond very poorly to the currently available chemotherapeutic drugs. We present a case of epithelioid sarcoma in which complete remission of pulmonary metastases was observed after treatment with a single agent, navelbine, a vinca alkaloid, and a potential therapeutic agent. The patient has been persistently free of metastases for 4 years since treatment with navelbine. Further studies are warranted to establish the role of navelbine for the treatment of soft tissue sarcoma and their metastases.
authors.affiliation: Departments of Medicine, University of Toledo, Toledo, OH, USA. zeeshan.tariq@utoledo.edu
authors.forename: Zeeshan
authors.initials: Z
authors.lastname: Tariq
authors.forename: Abhimanyu
authors.initials: A
authors.lastname: Ghose
authors.forename: Muhammad Z
authors.initials: MZ
authors.lastname: Bawany
authors.forename: Bilal
authors.initials: B
authors.lastname: Saeed
authors.forename: Iman
authors.initials: I
authors.lastname: Mohamed
authors.forename: David
authors.initials: D
authors.lastname: Harmon
mesh_terms: D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D005542:Forearm; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012074:Remission Induction / Q000379:methods; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077235:Vinorelbine
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D000077235:Vinorelbine