title: Pre-operative transarterial embolization for treatment of primary sacral tumors.
abstract: Pre-operative embolization of hypervascular spinal tumors can be helpful in tumour resection; however, few studies have been reported on its effectiveness in sacral tumors. We aimed to investigate the value of surgical excision with pre-operative transarterial embolization for primary sacral tumors and evaluate the long-term follow-up outcomes. Data were obtained from a consecutive series of 60 patients (33 female, 27 male) who had sacral tumors and who, between 1992 and 2007, underwent surgical excision in conjunction with arterial embolization. The evaluation parameters included intraoperative blood loss, transfusion, treatment, local recurrence and complications associated with surgery. All tumor masses were resected without intraoperative shock or death. The mean intraoperative blood loss was 1168.3mL (range: 200-5700mL) and the mean transfusion amount was 5.2 units (range: 0-35 units). Radical wide excision was performed on eight patients, marginal excision was conducted for 34 patients and intralesional excision was undertaken for the remaining 18 patients. The mean follow-up period was 75.2months (range: 15-180months). Nineteen (31.7%) patients developed local recurrences. Of the patients who had at least the second sacral roots and the unilateral S3 preserved, 33 (84.6%) had normal bladder function and 34 (87.2%) had normal bowel control. Pre-operative arterial embolization may significantly reduce the likelihood of intraoperative hemorrhage, and has the potential to assist surgeons in completing tumor resection and improving the outcomes for these patients.
authors.affiliation: Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, No. 188 ShiZi Street, Suzhou 215006, Jiang Su, China.
authors.forename: Hui-Lin
authors.initials: HL
authors.lastname: Yang
authors.forename: Kang-Wu
authors.initials: KW
authors.lastname: Chen
authors.forename: Gen-Lin
authors.initials: GL
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Lu
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Ji
authors.forename: Jia-Yong
authors.initials: JY
authors.lastname: Liu
authors.forename: Gui-Zhong
authors.initials: GZ
authors.lastname: Wu
authors.forename: Yong
authors.initials: Y
authors.lastname: Gu
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction / Q000379:methods; D002817:Chordoma / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012447:Sacrum / Q000473:pathology* / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000628:therapy*; D055815:Young Adult