title: Correlation between canal paresis and spontaneous nystagmus during early stage of acute peripheral vestibular disorders.
abstract: CONCLUSIONS
  This study demonstrates that the resolution period of spontaneous nystagmus (SN) may provide an indication of vestibular dysfunction on a particular day in the primary care setting.
  
  
  OBJECTIVE
  We aimed to predict canal paresis using fundamental observations of SN during the early stage of acute peripheral vestibular disorders.
  
  
  METHODS
  The study involved 87 patients who had recently experienced their first episode of acute spontaneous vertigo and direction-fixed horizontal nystagmus. Although they did not exhibit any other neurological deficits, they had been hospitalized with severe acute symptoms between 2004 and 2007. A correlation between the resolution period of SN and the results of laboratory caloric testing was reviewed.
  
  
  RESULTS
  The receiver operating characteristic analysis showed that the resolution period of SN may be a predictive indicator of unilateral vestibular hypofunction in the acute stage. In about half of the patients, SN disappeared on the third day after their initial visit. However, in 20% of the patients SN still persisted on the eighth day. Among the patients with SN, the prevalence of canal paresis increased with the increase in the resolution period of SN. When SN was observed on the fifth day, the prevalence was approximately 70%.
authors.affiliation: Department of Otolaryngology, Head & Neck Surgery, University of Toyama, Toyama, Japan. hfushiki@med.u-toyama.ac.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Fushiki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ishida
authors.forename: Shigeki
authors.initials: S
authors.lastname: Sumi
authors.forename: Akira
authors.initials: A
authors.lastname: Naruse
authors.forename: Yukio
authors.initials: Y
authors.lastname: Watanabe
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002150:Caloric Tests; D004584:Electronystagmography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000175:diagnosis*; D010291:Paresis / Q000175:diagnosis*; D012075:Remission, Spontaneous; D012665:Semicircular Canals; D015837:Vestibular Diseases / Q000175:diagnosis*; D014724:Vestibular Function Tests; D020338:Vestibular Neuronitis / Q000175:diagnosis*