title: Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature.
abstract: Schwannomas, also known as neurilemmomas, are uncommon neoplasms apparently derived from Schwann cells. The growth of these tumors causes displacement and compression of the nerve of origin. Schwannomas are usually solitary lesions but can be multiple when associated with neurofibromatosis. Anti-S100 protein is the most widely used antibody for the identification of this neoplasm. Surgical excision is the treatment of choice for schwannomas, with few and controversial reports of recurrence or malignant transformation. The present article reports 7 additional cases of oral schwannoma, and the literature is reviewed regarding clinicopathologic features, immunohistochemical findings, differential diagnosis, and therapeutic management of this benign neural tumor.
authors.affiliation: Postgraduation Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
authors.forename: Pedro Paulo de Andrade
authors.initials: PP
authors.lastname: Santos
authors.forename: Valéria Souza
authors.initials: VS
authors.lastname: Freitas
authors.forename: Leão Pereira
authors.initials: LP
authors.lastname: Pinto
authors.forename: Roseana de Almeida
authors.initials: Rde A
authors.lastname: Freitas
authors.forename: Lélia Batista
authors.initials: LB
authors.lastname: de Souza
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D055815:Young Adult