Stereocontrolled synthesis of quaternary cyclopropyl esters.
Treatment of a variety of enantiopure terminal epoxides with the anion of a range of 2-substituted triethylphosphonoacetates leads to an array of quaternary cyclopropyl esters with high yield and diastereocontrol.
Bray
Christopher D
CD
Queen Mary University of London, School of Biological and Chemical Sciences, Mile End Road, London, E1 4NS, UK. c.bray@qmul.ac.uk
Minicone
Fabrizio
F