Histological and histomorphometrical comparative study of β-tricalcium phosphate block grafts and periosteal expansion osteogenesis for alveolar bone augmentation.
This study evaluated local tissue reaction around the β-tricalcium phosphate (β-TCP) block and compared results with β-TCP block grafting and periosteal expansion osteogenesis (PEO). The mandibular premolars were extracted from five dogs and buccal corticotomy was performed. Narrow alveolar ridge models were created at 4 weeks. The β-TCP block graft, such as veneer graft, was used on the right side and PEO using β-TCP block on the left side. Changes of alveolar width, histological findings and histomorphometrical analysis were evaluated. There were no problems with materials at any of the sites at any time. In both groups, the width increased after surgery and results were stable 8 weeks after surgery. Newly formed bone tissue was observed inside the β-TCP block in both sides. Histological findings differed especially at the division between mandibular bone and β-TCP block. Histomorphometric analyses revealed that β-TCP had been absorbed (mean decrease 28%) and new bone had formed (mean increase 43%) at 8 weeks postoperatively on both sides. The β-TCP block worked as a space-maker under the soft tissue, including the periosteum, and acted as a substitute for original bone. This bone substitute was effective material for bone augmentation in both methods.
Yamauchi
K
K
Department of Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Reconstructive Surgery, Kyushu Dental College, Kitakyushu, Fukuoka, Japan. k-yama@kyu-dent.ac.jp
Takahashi
T
T
Funaki
K
K
Hamada
Y
Y
Yamashita
Y
Y
D020341:Absorbable Implants; D000539:Alveolar Process / Q000473:pathology; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use*; D002508:Cephalometry; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D015726:Giant Cells / Q000473:pathology; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008336:Mandibular Diseases / Q000601:surgery; D010006:Osteoblasts / Q000473:pathology; D010011:Osteocytes / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology; D019857:Osteogenesis, Distraction / Q000379:methods*; D010521:Periosteum / Q000473:pathology / Q000601:surgery; D013997:Time Factors
D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate