Reactive nodular hyperplasia mimicking malignant lymphoma in donor liver allograft.
The transmission of malignancy from donor to recipient can have devastating outcomes. Therefore, careful examination of the thoracic cavity, abdominal organs, and lymphoid tissue is important. In this report, we have described a case of a healthy 37-year-old donor with no significant past medical history who was found to have a nodule in the liver allograft during the examination at the back table. The frozen section revealed atypical lymphoid hyperplasia. Further workup revealed a rare benign lesion in the liver known as reactive lymphoid hyperplasia. Unfortunately, the liver allograft had to be discarded since low-grade lymphoma could not be excluded at the time of transplantation.
Sibulesky
L
L
Departments of Transplantation and Pathology, Mayo Clinic, Jacksonville, Florida 32224, USA.
Satyanarayana
R
R
Menke
D
D
Nguyen
J H
JH
D000328:Adult; D001926:Brain Death; D002102:Cadaver; D003937:Diagnosis, Differential; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000175:diagnosis*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis*; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000592:standards*