[Clinical efficacy of Yangjing Decoction on idiopathic asthenozoospermia].
OBJECTIVE
To evaluate the clinical effect of the Chinese medicine Yangjing Decoction on idiopathic asthenospermia.


METHODS
This study included 62 patients with idiopathic asthenospermia diagnosed with the computer-assisted semen analysis system and other methods based on the WHO guidelines. The patients were equally randomized to a trial and a control group, the former treated with Yangjing Decoction at the dose of 400 ml bid, and the latter with Yougui Capsules tid, both for a course of 6 months. Then we analyzed the changes in sperm concentration and percentage of grade a + b sperm in the patients, as well as the pregnancy in their wives.


RESULTS
Compared with the controls, the patients of the trial group showed a significantly elevated percentage of grade a + b sperm after 6 months medication (P < 0.01), though no statistically significant differences were observed in sperm concentration (P > 0.05). The total rate of effectiveness was 87.09% and 7 pregnancies were achieved in the trial group, as compared with 66.74% and 3 pregnancies in the controls (P < 0.05).


CONCLUSIONS
Yangjing Decoction can significantly improve sperm vitality, and has a desirable effect on idiopathic asthenospermia.
Shen
Shu-Lin
SL
Department of Andrology, Liuzhou Hospital of Traditional Chinese Medicine, Liuzhou, Guangxi 545001, China. shenforest@163.com
Zhao
Qian
Q
Xu
Gang
G
Li
Xiong-Wei
XW
Tu
Hai-Shuang
HS
D000328:Adult; D053627:Asthenozoospermia / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000188:drug therapy; D008517:Phytotherapy; D011247:Pregnancy; D016896:Treatment Outcome; D055815:Young Adult
D004365:Drugs, Chinese Herbal