title: The DUBle life of polycomb complexes.
abstract: Many Polycomb group (PcG) proteins assemble into complexes containing histone-modifying enzymes that act in concert to control developmental regulators. In a recent study in Nature, Scheuermann et al. report the identification of a PcG complex with histone H2A-specific deubiquitinase activity that may be a key player in PcG-target gene regulation.
authors.affiliation: Institut de Génétique Humaine, CNRS, 141, rue de la Cardonille, 34396 Montpellier Cedex 5, France.
authors.forename: Bernd
authors.initials: B
authors.lastname: Schuettengruber
authors.forename: Giacomo
authors.initials: G
authors.lastname: Cavalli