title: Stabilized alpha-helix-catalyzed enantioselective epoxidation of alpha,beta-unsaturated ketones.
abstract: Chiral cyclic alpha-amino acid containing oligopeptide catalyzed highly enantioselective epoxidation of alpha,beta-unsaturated ketones and the alpha-helical secondary structure of the peptide catalyst were revealed by X-ray crystallographic analysis.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Masanobu
authors.initials: M
authors.lastname: Nagano
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Doi
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kurihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suemune
authors.forename: Masakazu
authors.initials: M
authors.lastname: Tanaka
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008968:Molecular Conformation; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D017433:Protein Structure, Secondary; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D007659:Ketones; D010455:Peptides