title: Model-order selection in Zernike polynomial expansion of corneal surfaces using the efficient detection criterion.
abstract: Corneal-height data are typically measured with videokeratoscopes and modeled using a set of orthogonal Zernike polynomials. We address the estimation of the number of Zernike polynomials, which is formalized as a model-order selection problem in linear regression. Classical information-theoretic criteria tend to overestimate the corneal surface due to the weakness of their penalty functions, while bootstrap-based techniques tend to underestimate the surface or require extensive processing. In this paper, we propose to use the efficient detection criterion (EDC), which has the same general form of information-theoretic-based criteria, as an alternative to estimating the optimal number of Zernike polynomials. We first show, via simulations, that the EDC outperforms a large number of information-theoretic criteria and resampling-based techniques. We then illustrate that using the EDC for real corneas results in models that are in closer agreement with clinical expectations and provides means for distinguishing normal corneal surfaces from astigmatic and keratoconic surfaces.
authors.affiliation: Signal Processing Group, Institute of Telecommunications, Technische Universität Darmstadt, 64283 Darmstadt, Germany. alkhaldi@spg.tu-darmstadt.de
authors.forename: Weaam
authors.initials: W
authors.lastname: Alkhaldi
authors.forename: D Robert
authors.initials: DR
authors.lastname: Iskander
authors.forename: Abdelhak M
authors.initials: AM
authors.lastname: Zoubir
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D003198:Computer Simulation; D003315:Cornea / Q000033:anatomy & histology*; D019781:Corneal Topography / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D016014:Linear Models; D008954:Models, Biological; D008962:Models, Theoretical