title: Reversible hypomagnesaemia-induced subacute cerebellar syndrome.
abstract: Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbeat nystagmus, cerebellar ataxia, generalised convulsions and a supraventricular tachycardia. On MRI imaging, a transient lesion of the cerebellar nodulus was observed, which has not, to our knowledge, been previously described in isolated hypomagnesaemia.
authors.affiliation: Department of Neurology, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, UK. ssedehizadeh@doctors.org.uk
authors.forename: Saam
authors.initials: S
authors.lastname: Sedehizadeh
authors.forename: Michael
authors.initials: M
authors.lastname: Keogh
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Wills
mesh_terms: D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008275:Magnesium Deficiency / Q000150:complications* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male