title: Single-dose volume regulation algorithm for a gas-compensated intrathecal infusion pump.
abstract: The internal pressures of medication reservoirs of gas-compensated intrathecal medication infusion pumps decrease when medication is discharged, and these discharge-induced pressure drops can decrease the volume of medication discharged. To prevent these reductions, the volumes discharged must be adjusted to maintain the required dosage levels. In this study, the authors developed an automatic control algorithm for an intrathecal infusion pump developed by the Korean National Cancer Center that regulates single-dose volumes. The proposed algorithm estimates the amount of medication remaining and adjusts control parameters automatically to maintain single-dose volumes at predetermined levels. Experimental results demonstrated that the proposed algorithm can regulate mean single-dose volumes with a variation of <3% and estimate the remaining medication volume with an accuracy of >98%.
authors.affiliation: Biomedical Engineering Branch, National Cancer Center, Goyang, Gyeonggi-do Korea.
authors.forename: Kyoung Won
authors.initials: KW
authors.lastname: Nam
authors.forename: Kwang Gi
authors.initials: KG
authors.lastname: Kim
authors.forename: Mun Hyun
authors.initials: MH
authors.lastname: Sung
authors.forename: Seong Wook
authors.initials: SW
authors.lastname: Choi
authors.forename: Dae Hyun
authors.initials: DH
authors.lastname: Kim
authors.forename: Yung Ho
authors.initials: YH
authors.lastname: Jo
mesh_terms: D000465:Algorithms; D004867:Equipment Design; D007260:Infusion Pumps; D007278:Injections, Spinal / Q000295:instrumentation*