title: Quantitative computed tomography.
abstract: Unlike dual x-ray absorptiometry and high-resolution CT scan and MR imaging techniques, which are largely restricted to the peripheral skeleton owing to radiation dose and signal-to-noise considerations, volumetric quantitative measures provide measures of cortical and trabecular volumetric bone mineral density, cross-sectional geometry, and estimates of whole-bone strength based on patient specific finite element modeling. This article focuses on the application of volumetric quantitative measures to studies of aging, disuse, and drug treatment as related to osteoporosis.
authors.affiliation: Joint Bioengineering Graduate Group, and Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, CA 94143-0946, USA. Thomas.Lang@Radiology.ucsf.edu
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Lang
mesh_terms: D015519:Bone Density; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology; D006615:Hip / Q000000981:diagnostic imaging; D006620:Hip Fractures / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D010024:Osteoporosis / Q000150:complications / Q000000981:diagnostic imaging*; D013131:Spine / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*