Liposomes: technologies and analytical applications.
Liposomes are structurally and functionally some of the most versatile supramolecular assemblies in existence. Since the beginning of active research on lipid vesicles in 1965, the field has progressed enormously and applications are well established in several areas, such as drug and gene delivery. In the analytical sciences, liposomes serve a dual purpose: Either they are analytes, typically in quality-assessment procedures of liposome preparations, or they are functional components in a variety of new analytical systems. Liposome immunoassays, for example, benefit greatly from the amplification provided by encapsulated markers, and nanotube-interconnected liposome networks have emerged as ultrasmall-scale analytical devices. This review provides information about new developments in some of the most actively researched liposome-related topics.
Jesorka
Aldo
A
Department of Chemical and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden. aldo.jesorka@chalmers.se
Orwar
Owe
O
D015374:Biosensing Techniques; D002623:Chemistry Techniques, Analytical; D004337:Drug Carriers; D016503:Drug Delivery Systems / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D018014:Gene Transfer Techniques; D008081:Liposomes / Q000737:chemistry*; D046911:Macromolecular Substances; D008422:Materials Testing; D004364:Pharmaceutical Preparations; D012107:Research Design; D012995:Solubility
D004337:Drug Carriers; D008081:Liposomes; D046911:Macromolecular Substances; D004364:Pharmaceutical Preparations