Unraveling the mechanism of the singlet oxygen ene reaction: recent computational and experimental approaches.
The mechanism of the singlet oxygen ene reaction has been a subject of renewed interest within the last few years. The main question being whether this reaction proceeds through a concerted mechanism or if it involves discrete intermediates. In general, the majority of experimental and computational studies support a traditional stepwise mechanism involving a perepoxide-like intermediate. In this minireview we highlight the most prominent and recent theoretical, as well as experimental results relating to the challenging mechanism of the singlet oxygen ene oxyfunctionalization.
Alberti
Mariza N
MN
Department of Chemistry, University of Crete, 71003 Voutes Campus, Heraklion, Crete, Greece.
Orfanopoulos
Michael
M
D000475:Alkenes / Q000737:chemistry*; D003198:Computer Simulation; D008956:Models, Chemical; D015394:Molecular Structure; D026082:Singlet Oxygen / Q000737:chemistry*
D000475:Alkenes; D026082:Singlet Oxygen