title: The efficacy of crude extract of Aloe secundiflora on Candida albicans.
abstract: In-vitro studies on the efficacy of crude extracts of Aloe secundiflora on Candida albicans was conducted. Five mature leaves of Aloe secundiflora were collected and the crude extract was prepared, then autoclaved. The extract was then tested on Candida albicans grown on solid media. The results from these studies revealed complete inhibition of Candida albicans growth caused by Aloe secundiflora crude extract on solid media. The findings from this study suggest that the crude extract of Aloe secundiflora can inhibit the growth of Candida albicans. Further studies are required to establish the in-vivo activity of the crude extract, the active ingredient, dosage and safety of Aloe secundiflora, before recommending for clinical use.
authors.affiliation: Department of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Chuo Kikuu, Morogoro. msoffepl@suanet.ac.tz
authors.forename: Peter L M
authors.initials: PL
authors.lastname: Msoffe
authors.forename: Z M
authors.initials: ZM
authors.lastname: Mbilu
mesh_terms: D000504:Aloe / Q000737:chemistry*; D000880:Anthraquinones / Q000494:pharmacology*; D000946:Antigens, Fungal; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves
chemical_list: D000880:Anthraquinones; D000946:Antigens, Fungal; D010936:Plant Extracts