title: Nonadherence to clinical practice guidelines and medications for multiple chronic conditions in a California Medicaid population.
abstract: OBJECTIVE
  To assess and profile quality of care in California Medicaid beneficiaries with chronic conditions.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  California from 2002 to 2004.
  
  
  METHODS
  1,123,577 beneficiaries.
  
  
  METHODS
  Eligibility and claims data (2002-2004) were used to identify beneficiaries with dyslipidemia, hypertension, coronary artery disease (CAD), heart failure, or diabetes.
  
  
  METHODS
  Quality of care was based on nonadherence with clinical practice guidelines including recommended medications. Chi-square was used to evaluate nonadherence and patient characteristics.
  
  
  RESULTS
  The proportion of patients without a prescription fill for recommended medications varied by disease (43% hypertension, 40% dyslipidemia and CAD, and 25% diabetes and heart failure). For Medicaid-only beneficiaries with diabetes, 78% lacked glycosylated hemoglobin tests, 62% lacked low-density lipoprotein cholesterol tests, and 50% lacked eye exams. Medication nonadherence was high (69% hypertension, 64% CAD, 57% heart failure, 48% dyslipidemia, 41% diabetes). Overall, younger age, Medicaid-only status, and black/other race were associated with poorer rates.
  
  
  CONCLUSIONS
  Quality of care was suboptimal, with nonadherence varying by condition. Programs targeting both patients and providers and addressing patient-related characteristics (e.g., age, race) and policy reform addressing alterable factors (e.g., insurance eligibility) should be developed to improve guideline adherence.
authors.affiliation: Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, USA. mnichol@usc.edu
authors.forename: Michael B
authors.initials: MB
authors.lastname: Nichol
authors.forename: Tara K
authors.initials: TK
authors.lastname: Knight
authors.forename: Julie L
authors.initials: JL
authors.lastname: Priest
authors.forename: Joanne
authors.initials: J
authors.lastname: Wu
authors.forename: C Ron
authors.initials: CR
authors.lastname: Cantrell
mesh_terms: D000368:Aged; D002140:California; D002908:Chronic Disease / Q000188:drug therapy* / Q000628:therapy*; D015331:Cohort Studies; D005260:Female; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008484:Medicaid; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D014481:United States