Effectiveness of 100% autologous serum drops in ocular surface disorders.
OBJECTIVE
To evaluate the effectiveness of 100% autologous serum eye drops for the treatment of various ocular surface disorders.


METHODS
A descriptive prospective observational study carried out from May 2005 to February 2009 which included patients with ocular surface disorders treated with single-dose autologous serum eye drops. Treatment effectiveness was evaluated by using a clinical questionnaire in order to assess symptoms experienced by patients at the beginning and end of treatment.


RESULTS
A total of 15 patients (24 eyes) were evaluated. Clinical symptoms such as redness, burning, sharp pain and tired eyes improved in 100% of the patients, whereas dryness and sandy/gritty sensation improved in 92% of the patients. The overall improvement of clinical symptoms was worth the inconvenience of venipuncture according to 66.7% of the patients. Regarding tolerance for autologous serum eye drops, only one patient experienced some discomfort when using the single-dose eye drops.


CONCLUSIONS
The treatment with 100% autologous serum eye drops improved ocular symptoms for most patients.
Jover Botella
A
A
Servicio de Farmacia, Hospital General Universitario de Alicante, Alicante, España.
Márquez Peiró
J F
JF
Márques
K
K
Monts Cambero
N
N
Selva Otaolaurruchi
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005128:Eye Diseases / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage; D011446:Prospective Studies; D044967:Serum
D009883:Ophthalmic Solutions