title: Intermediate-term EVAR outcomes in octogenarians.
abstract: OBJECTIVE
  The utilization of endovascular abdominal aortic aneurysm repair (EVAR) in suitable patients has resulted in decreased perioperative morbidity and mortality. Octogenarians as a subgroup have been more readily offered EVAR, as it is less invasive, and therefore presumably better tolerated than conventional open aortic repair. The purpose of this study is to investigate periprocedural and late EVAR outcomes in octogenarians compared with patients less than 80 years of age.
  
  
  METHODS
  From January 2003 to May 2008, 322 patients underwent EVAR. A total of 117 octogenarians were compared with 205 patients less than 80 years of age. A retrospective review of the demographic data, aneurysm details, perioperative morbidity, mortality, and late outcomes were analyzed.
  
  
  RESULTS
  Octogenarians were significantly more likely to have a history of diabetes mellitus (51% vs 23%; P < .001), coronary artery disease (45% vs 32%; P = .0165), chronic obstructive pulmonary disease (44% vs 30%; P = .0113), and renal insufficiency (57% vs 31%; P < .0001). There were no significant differences in the rates of perioperative myocardial infarction, stroke, death, intestinal, or arterial ischemic complications between the two groups. Octogenarians had a significant higher rate of pulmonary complications (5.1% vs 1%; P < .03) and access-site hematomas (12% vs 2.4%; P = .001) than younger patients. When all significant perioperative morbidity was combined, octogenarians were twice as likely to develop complications following EVAR than younger patients (27.4% vs 11.7%; P = .001). At 5-year follow-up, younger patients were twice as likely to develop type II endoleaks.
  
  
  CONCLUSIONS
  EVAR can be performed safely and effectively in octogenarians, and the incidence of major complications including myocardial infarction, stroke, and death is unchanged compared with younger patients. However, there is a significantly increased rate of access-site hematomas, pulmonary, and perioperative complications in octogenarians as a whole. Our findings suggest EVAR remains a suitable form of therapy in the elderly group provided there is an appropriate preoperative evaluation and perioperative monitoring following repair.
authors.affiliation: NYU Medical Center, New York, NY 10016, USA.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Fonseca
authors.forename: Caron
authors.initials: C
authors.lastname: Rockman
authors.forename: Abhishek
authors.initials: A
authors.lastname: Pitti
authors.forename: Neal
authors.initials: N
authors.lastname: Cayne
authors.forename: Tom S
authors.initials: TS
authors.lastname: Maldonado
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Lamparello
authors.forename: Thomas
authors.initials: T
authors.lastname: Riles
authors.forename: Mark
authors.initials: M
authors.lastname: Adelman
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000401:mortality; D016009:Chi-Square Distribution; D005260:Female; D006406:Hematoma / Q000209:etiology; D006801:Humans; D053208:Kaplan-Meier Estimate; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology; D009519:New York City; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D020521:Stroke / Q000209:etiology; D013997:Time Factors; D016896:Treatment Outcome