title: [Propylthiouracil-induced multispecific antineutrophil cytoplasmic antibodies].
abstract: We report the case of a 28-year-old woman who presented with arthralgia during a treatment with propylthiouracil (PTU) for hyperthyroidism. Detection of antineutrophil cytoplasmic antibodies (ANCA) against myeloperoxidase, proteinase 3 and elastase led to suspect PTU induced vasculitis.
authors.affiliation: Service de biochimie, hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France. a_servonnet@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Servonnet
authors.forename: C
authors.initials: C
authors.lastname: Garcia-Hejl
authors.forename: F
authors.initials: F
authors.lastname: Banal
authors.forename: J
authors.initials: J
authors.lastname: Ramirez
authors.forename: E
authors.initials: E
authors.lastname: Fontan
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D013956:Antithyroid Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011441:Propylthiouracil / Q000009:adverse effects*; D014657:Vasculitis / Q000139:chemically induced* / Q000276:immunology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D013956:Antithyroid Agents; D011441:Propylthiouracil