title: An attack of acute neuro-Behçet's disease during the course of chronic progressive neuro-Behçet's disease: report of two cases.
abstract: A 29-year-old man and a 36-year-old man developed attacks of acute neuro-Behçet's disease (NB) (right Horner's syndrome and right hemiplegia and dysarthria, respectively) during the course of chronic progressive NB (acute on chronic). Although both patients recovered from acute NB after treatment with infliximab or corticosteroids, they continued to show manifestations of chronic progressive NB. It is suggested that acute NB and chronic progressive NB are different in their pathogenesis.
authors.affiliation: Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Matsui
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishida
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tono
authors.forename: Takuhiro
authors.initials: T
authors.lastname: Yoshida
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Sato
authors.forename: Shunsei
authors.initials: S
authors.lastname: Hirohata
mesh_terms: D000208:Acute Disease; D000328:Adult; D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001284:Atrophy; D001528:Behcet Syndrome / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D002908:Chronic Disease; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D000069285:Infliximab; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D005938:Glucocorticoids; D000069285:Infliximab