Adsorption of delmopinol at the solid/liquid interface--the role of the acid-base equilibrium.
Delmopinol is a tertiary amine surfactant that is used to counteract dental plaque formation. As it is of interest to understand the interfacial behavior from both fundamental and applied perspectives the adsorption of delmopinol to model surfaces was investigated. Adsorption on Teflon, titanium and stainless steel was studied by radioactive labeling and adsorption on silica was studied by quartz crystal microbalance (QCM), ellipsometry and particle electrophoresis. It was shown that the adsorption of delmopinol was complex and strongly influenced by pH and concentration. Pronounced peak values were detected in the adsorption curves (adsorbed amount versus concentration) exceeding the expected value for a bilayer type of structure. To account for this behavior two surface active component were assumed to be present. Accordingly, the high amounts result from the deposition of the component with lower solubility and the decrease at the critical micelle concentration can be explained by solubilization of this component. Based on data from several experimental methods and the pH dependence of the effect we propose an explanation in which the protonated and non-protonated forms of delmopinol represent the two components. However, it cannot be excluded that the component with the lower solubility could be a compound chemically different from delmopinol in the sample.
Svensson
Olof
O
Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden. olof.svensson@mah.se
Halthur
Tobias
T
Sjödin
Torgny
T
Arnebrant
Thomas
T
D000136:Acid-Base Equilibrium; D000327:Adsorption; D015394:Molecular Structure; D009025:Morpholines / Q000737:chemistry*; D009067:Mouthwashes / Q000737:chemistry; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*
D009025:Morpholines; D009067:Mouthwashes; D013501:Surface-Active Agents; C073738:delmopinol