Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature.
Schwannomas, also known as neurilemmomas, are uncommon neoplasms apparently derived from Schwann cells. The growth of these tumors causes displacement and compression of the nerve of origin. Schwannomas are usually solitary lesions but can be multiple when associated with neurofibromatosis. Anti-S100 protein is the most widely used antibody for the identification of this neoplasm. Surgical excision is the treatment of choice for schwannomas, with few and controversial reports of recurrence or malignant transformation. The present article reports 7 additional cases of oral schwannoma, and the literature is reviewed regarding clinicopathologic features, immunohistochemical findings, differential diagnosis, and therapeutic management of this benign neural tumor.
Santos
Pedro Paulo de Andrade
PP
Postgraduation Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Freitas
Valéria Souza
VS
Pinto
Leão Pereira
LP
Freitas
Roseana de Almeida
Rde A
de Souza
Lélia Batista
LB
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000601:surgery; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D055815:Young Adult