title: Nanoscopic porous sensors.
abstract: There are thousands of different nanometer-scale pores in biology, many of which act as sensors for specific chemical agents. Recent work suggests that protein and solid-state nanopores have many potential uses in a wide variety of analytical applications. In this review we survey this field of research and discuss the prospects for advances that could be made in the near future.
authors.affiliation: National Institute of Standards and Technology, Gaithersburg, Maryland 20899-8120, USA. john.kasianowicz@nist.gov
authors.forename: John J
authors.initials: JJ
authors.lastname: Kasianowicz
authors.forename: Joseph W F
authors.initials: JW
authors.lastname: Robertson
authors.forename: Elaine R
authors.initials: ER
authors.lastname: Chan
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Reiner
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Stanford
mesh_terms: D000818:Animals; D001703:Biophysics / Q000379:methods*; D002623:Chemistry Techniques, Analytical; D004269:DNA, Bacterial / Q000378:metabolism; D005583:Fourier Analysis; D006801:Humans; D008390:Markov Chains; D008968:Molecular Conformation; D053761:Nanocomposites; D036103:Nanotechnology / Q000379:methods*; D016062:Porosity
chemical_list: D004269:DNA, Bacterial