title: [A case report of familial AVM].
abstract: Genetic analysis of the familials of patients with arteriovenous malformation (AVM) has a significant potential to reveal the etiology of this disease, although neither the detailed etiology nor pathogenesis of AVM has been fully elucidated to date. While a history of AVM is apparent in 2% of stroke patients, familial occurrence of AVM is very rare. We describe an interesting familial case of AVM. This also represents a rare pattern of familial occurrence in that patients are not likely hereditary hemorrhagic telangiectasia (HHT). There is a possibility that such familial AVMs are associated with unknown genes other than HHT genes.
authors.affiliation: Department of Neurosurgery, University of Nara Medical Graduate School, Kashihara-city, Nara, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Wajima
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeshima
authors.forename: Kentaro
authors.initials: K
authors.lastname: Tamura
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Motoyama
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Hirabayashi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakase
mesh_terms: D005190:Family; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000235:genetics*; D008297:Male; D008875:Middle Aged