title: [Antiplatelet therapy in patients with chronic obliterating diseases of lower-limb arteries].
abstract: The article deals with present-day evidence concerning the role of blood-platelet activity in the development of a pathological process and acute ischemia in patients presenting with chronic arterial insufficiency of the lower extremities. Proved herein is the necessity of long-term administration of antiplatelet drugs in order to prevent vascular complications on the part of the heart, brain, and peripheral arteries, with a description of the drugs most commonly used for these purposes.
authors.forename: M R
authors.initials: MR
authors.lastname: Kuznetsov
authors.forename: S A
authors.initials: SA
authors.lastname: Tepliakov
authors.forename: A V
authors.initials: AV
authors.lastname: Sizarev
authors.forename: B V
authors.initials: BV
authors.lastname: Tugdumov
authors.forename: N S
authors.initials: NS
authors.lastname: Dzhalilova
mesh_terms: D001162:Arteriosclerosis Obliterans / Q000188:drug therapy* / Q000601:surgery; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002908:Chronic Disease; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013270:Stomach / Q000187:drug effects; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin