title: Neuroticism, cognitive ability, and the metabolic syndrome: The Vietnam Experience Study.
abstract: OBJECTIVE
  The purpose of this study is to explore the association of neuroticism with the metabolic syndrome, separate components of the metabolic syndrome, and the number of components of metabolic syndrome an individual possesses. The purpose of this study is to examine also the extent to which any associations are accounted for by sociodemographic factors, health behaviors, and cognitive ability.
  
  
  METHODS
  Participants were 4208 men drawn from the Vietnam Experience Study. From military archives, and a later telephone interview and psychological and medical examination, sociodemographic, health behavior, cognitive ability, neuroticism, and health data were collected. Neuroticism and cognitive ability were assessed with standardized tests during the medical examination. Presence of the metabolic syndrome was based on body mass index, fasting blood glucose or a diagnosis of diabetes, high blood pressure or taking antihypertensive medication, high-density lipoprotein cholesterol, and triglyceride levels.
  
  
  RESULTS
  Neuroticism was positively associated with the occurrence of the metabolic syndrome and several of its components in both age-, and sociodemographic- and health behavior-adjusted analyses. Many associations were accounted for by individual difference in cognitive ability. Neuroticism was robustly associated with the number of components of the metabolic syndrome after adjustment.
  
  
  CONCLUSIONS
  Individuals with higher neuroticism scores had a higher prevalence of the metabolic syndrome and a larger number of its components. On the whole, differences in cognitive ability appeared to partially mediate the relationship between neuroticism and the metabolic syndrome.
authors.affiliation: School of Sport and Exercise Sciences, University of Birmingham, UK. a.c.phillips@bham.ac.uk
authors.forename: Anna C
authors.initials: AC
authors.lastname: Phillips
authors.forename: G David
authors.initials: GD
authors.lastname: Batty
authors.forename: Alexander
authors.initials: A
authors.lastname: Weiss
authors.forename: Ian
authors.initials: I
authors.lastname: Deary
authors.forename: Catharine R
authors.initials: CR
authors.lastname: Gale
authors.forename: G Neil
authors.initials: GN
authors.lastname: Thomas
authors.forename: Douglas
authors.initials: D
authors.lastname: Carroll
mesh_terms: D000328:Adult; D000367:Age Factors; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D015897:Comorbidity; D015438:Health Behavior; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D007360:Intelligence; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D008875:Middle Aged; D009497:Neurotic Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D012307:Risk Factors; D012959:Socioeconomic Factors; D013223:Statistics as Topic; D014280:Triglycerides / Q000097:blood; D014728:Veterans / Q000523:psychology*; D047829:Vietnam Conflict
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides