title: A sympathetic view on free radicals in diabetes.
abstract: Neuropathies are severe complications of diabetes. In this issue of Neuron, Campanucci et al. report that hyperglycemia-induced elevation of reactive oxygen species impairs synaptic transmission of sympathetic neurons leading to diabetes-induced dysautonomias. These observations provide new insights into the etiology of diabetic complications and suggest potential novel therapeutic approaches for neuropathies.
authors.affiliation: Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, New Haven, CT 06520, USA. sabrina.diano@yale.edu
authors.forename: Sabrina
authors.initials: S
authors.lastname: Diano
authors.forename: Tamas L
authors.initials: TL
authors.lastname: Horvath