Optical coherence tomography (OCT) in optic neuritis and multiple sclerosis.
Optical coherence tomography (OCT) is a non-invasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. It also provides information on optic nerve head topography, peripapillary retinal nerve fiber layer thickness, and macular volume, which correlate with axonal loss. These measurements are of particular interest in optic neuropathies and in multiple sclerosis, and OCT parameters are now used as endpoints in neurologic clinical trials.
Lamirel
C
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Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Newman
N J
NJ
Biousse
V
V
D001369:Axons / Q000473:pathology; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000473:pathology; D009471:Neuromyelitis Optica / Q000175:diagnosis / Q000473:pathology; D009902:Optic Neuritis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D055351:Retinal Neurons / Q000473:pathology; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome