Vascular changes at the puncture segments of arteriovenous fistula for hemodialysis access.
OBJECTIVE
Repeated puncture is a mechanical injury to the hemodialysis accesses. We systemically observed the vascular changes at the puncture segments of arteriovenous fistulas.


METHODS
The native arteriovenous fistulas in 104 patients on maintenance hemodialysis using the buttonhole technique for puncture were studied. We used the duplex scan to observe the intimal lesions, the maximal diameters at the arterial and venous puncture segments, and the references.


RESULTS
Intimal lesions were found in 42% and 40% of the arterial and venous puncture segments, none of which resulted in significant luminal stenosis. The differences between diameters at the arterial or venous puncture segments and the corresponding references were significant (arterial, 11.07 +/- 4.45 vs 6.85 +/- 2.35 mm, P < .001; venous, 8.82 +/- 4.13 vs 5.54 +/- 2.22 mm, P < .001). All segments, except only three arterial and four venous puncture segments, were larger than the corresponding references. The degree of vascular dilatation, defined as the diameter difference between the puncture segments and the references calibrated by the reference diameter, were 64.1 +/- 49.6% at arterial puncture segments and 59.9 +/- 42.2% at venous segments. Multivariate analysis revealed that the patient age and the puncture duration were strongly correlated with the degree of vascular dilatation at both the arterial (P = .018 and .007, respectively) and venous puncture segments (P = .020 and .011, respectively).


CONCLUSIONS
Puncture of arteriovenous fistula using a buttonhole technique resulted in a consistent vascular dilatation and moderately high incidence of intimal thickness, but no significant luminal stenosis was found.
Hsiao
Ju-Feng
JF
Cardiovascular Division, Department of Internal Medicine, Chia-Yi Chang Gung Memorial Hospital, Taiwan, Republic of China.
Chou
Hsin-Hua
HH
Hsu
Lung-An
LA
Wu
Lung-Sheng
LS
Yang
Chih-Wei
CW
Hsu
Tsu-Shiu
TS
Chang
Chi-Jen
CJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001132:Arm / Q000098:blood supply*; D001158:Arteries / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D001166:Arteriovenous Shunt, Surgical; D003251:Constriction, Pathologic; D003430:Cross-Sectional Studies; D004108:Dilatation, Pathologic; D005260:Female; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D011677:Punctures / Q000009:adverse effects; D006435:Renal Dialysis; D018570:Risk Assessment; D012307:Risk Factors; D013624:Taiwan; D018615:Ultrasonography, Doppler, Color; D014680:Veins / Q000293:injuries / Q000473:pathology / Q000503:physiopathology