title: Anti-allergic drugs and the Annexin-A1 system.
abstract: This paper, which was presented at the 17th JMRC 'John Robert Vane Memorial' Symposium, describes some recent work from the authors' laboratory that provides a tentative explanation for the anti-inflammatory effects produced by the cromoglycate-like anti-allergic drugs. Some of the implications of this finding are discussed.
authors.affiliation: Biochemical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
authors.forename: Samia
authors.initials: S
authors.lastname: Yazid
authors.forename: Samir S
authors.initials: SS
authors.lastname: Ayoub
authors.forename: Egle
authors.initials: E
authors.lastname: Solito
authors.forename: Simon
authors.initials: S
authors.lastname: McArthur
authors.forename: Phuong
authors.initials: P
authors.lastname: Vo
authors.forename: Neil
authors.initials: N
authors.lastname: Dufton
authors.forename: Roderick J
authors.initials: RJ
authors.lastname: Flower
mesh_terms: D017305:Annexin A1 / Q000378:metabolism*; D018926:Anti-Allergic Agents / Q000378:metabolism / Q000494:pharmacology*; D004205:Cromolyn Sodium / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism; D020298:U937 Cells
chemical_list: D017305:Annexin A1; D018926:Anti-Allergic Agents; D004205:Cromolyn Sodium