title: Adenomatous colorectal polyps in patients referred for colonoscopy in a regional hospital in Kuwait.
abstract: OBJECTIVE
  Adenomatous colorectal polyps (ACPs) are known to be the precursor lesions for colorectal cancer. The aim of the study was to determine the prevalence, endoscopic and pathological features of ACPs in patients referred for colonoscopy.
  
  
  METHODS
  The endoscopic and histological reports of adult patients who underwent complete colonoscopy in the gastroenterology unit of a regional Kuwaiti hospital between January 2008 and December 2008 were retrospectively studied. The specimens of polyps were reviewed by an experienced pathologist who was blinded to the clinical or endoscopic information. Non-neoplastic polyps were not included in the analysis.
  
  
  RESULTS
  Of 530 eligible patients (mean age, 45 years; male-female ratio, 2:1), 54 (10%) had 103 ACPs. Of the patients with ACPs (mean age, 57 years), 43 (80%) were males and 36 (67%) were Kuwaitis. Histopathological examination of the most significant polyp in each patient revealed that 40 (74%) polyps were tubular adenomas (TAs); 11 (20%), tubulovillous (TV) adenomas; and 3 (6%), villous adenomas. High-grade dysplasia was noticed in 4 (10%) adenomas. Fifteen (2.8%) of the 530 patients had advanced ACPs. Logistic regression analysis of some variables and their association with ACPs found that age (P < 0.001; OR, 1.9; CI, 1.5-2.3), history of adenoma (P=0.001; OR, 6.4; CI, .2.1-19.4) and being Kuwaitis (P=0.029; OR, 2.1; CI, 1.1-4.1) to be independently associated with ACPs.
  
  
  CONCLUSIONS
  The most common histological type of ACPs was tubular adenoma. Advancing age, being Kuwaiti nationals and prior removal of ACPs were significantly associated with the occurrence of ACPs.
authors.affiliation: Department of Medicine, Farwaniya Hospital, Ministry of Health, Kuwait.
authors.forename: Saleh A
authors.initials: SA
authors.lastname: Al-Enezi
authors.forename: Saqer A
authors.initials: SA
authors.lastname: Alsurayei
authors.forename: Ali E
authors.initials: AE
authors.lastname: Ismail
authors.forename: Nasser Yehia A
authors.initials: NY
authors.lastname: Aly
authors.forename: Waleed A
authors.initials: WA
authors.lastname: Ismail
authors.forename: Amany A
authors.initials: AA
authors.lastname: Abou-Bakr
mesh_terms: D018256:Adenomatous Polyps / Q000453:epidemiology* / Q000473:pathology; D016009:Chi-Square Distribution; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007730:Kuwait / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012189:Retrospective Studies