title: Cardiogenic shock due to tachycardiomyopathy after heart transplantation: successful treatment with ivabradine.
abstract: Tachycardia-induced cardiomyopathy refers to an impairment in left-ventricular function due to chronic or prolonged tachycardia. We describe a heart transplant patient who developed cardiogenic shock due to tachycardia-induced cardiomyopathy. Low-output failure was further aggravated by administration of a short-acting beta-blocker during invasive hemodynamic monitoring. In contrast, heart rate control by administration of increasing doses of ivabradine supported recovery from cardiogenic shock and led to an improvement in the patient's clinical condition as well as left-ventricular function during follow-up.
authors.affiliation: Department of Cardiology, University Hospital Aachen, Aachen, Germany. czwicker@ukaachen.de
authors.forename: C
authors.initials: C
authors.lastname: Zwicker
authors.forename: M
authors.initials: M
authors.lastname: Becker
authors.forename: W
authors.initials: W
authors.lastname: Lepper
authors.forename: K C
authors.initials: KC
authors.lastname: Koch
authors.forename: R
authors.initials: R
authors.lastname: Westenfeld
mesh_terms: D000328:Adult; D001552:Benzazepines / Q000494:pharmacology / Q000627:therapeutic use*; D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D002407:Catheterization, Swan-Ganz; D003937:Diagnosis, Differential; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D000077550:Ivabradine; D012770:Shock, Cardiogenic / Q000188:drug therapy* / Q000209:etiology; D013575:Syncope / Q000150:complications; D013610:Tachycardia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D001552:Benzazepines; D000077550:Ivabradine