Enantioselective cationic polyene cyclization vs enantioselective intramolecular carbonyl-ene reaction.
This paper describes highly efficient catalytic enantioselective cationic polyene cyclization and catalytic enantioselective intramolecular carbonyl-ene reaction in good to high yields with high enantioselectivities. The intimate relationship and mechanistic differences between the two enantioselective reactions were studied in detail. In addition, the cyclization products are versatile and useful building blocks for natural products and pharmaceuticals syntheses.
Zhao
Yu-Jun
YJ
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.
Li
Bin
B
Tan
Li-Jun Serena
LJ
Shen
Zhi-Liang
ZL
Loh
Teck-Peng
TP