title: Bile leak test by indocyanine green fluorescence images after hepatectomy.
abstract: Bile leak remains a serious complication after hepatectomy. The conventional leak test by intrabiliary injection of normal saline solution is not sensitive. The authors present a new bile leak test using indocyanine green (ICG) fluorescence. After hepatic transection, ICG solution (.05 mg/mL) was intrabiliarily injected through a transcystic tube under distal common bile duct clamping, and fluorescent images were visualized using an infrared camera system. The ICG leak test was performed in 27 patients undergoing hepatectomy without biliary reconstruction. Bile leaks were intraoperatively found in 8 patients and fixed, resulting in no postoperative leaks. There was no adverse reaction to ICG. In contrast, postoperative bile leaks occurred in 2 of 32 patients who received the conventional leak test with normal saline solution between April 2007 and March 2008. The new bile leak test by ICG fluorography is useful to prevent postoperative bile leak.
authors.affiliation: Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan. saka1119@hama-med.ac.jp
authors.forename: Takanori
authors.initials: T
authors.lastname: Sakaguchi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Suzuki
authors.forename: Naoki
authors.initials: N
authors.lastname: Unno
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Morita
authors.forename: Kosuke
authors.initials: K
authors.lastname: Oishi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Fukumoto
authors.forename: Keisuke
authors.initials: K
authors.lastname: Inaba
authors.forename: Minoru
authors.initials: M
authors.lastname: Suzuki
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sagara
authors.forename: Shohachi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakamura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konno
mesh_terms: D000368:Aged; D001646:Bile; D002763:Cholecystectomy / Q000009:adverse effects; D015331:Cohort Studies; D004396:Coloring Agents; D005260:Female; D005453:Fluorescence; D006498:Hepatectomy / Q000009:adverse effects*; D006801:Humans; D007208:Indocyanine Green; D007430:Intraoperative Care; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D013536:Suture Techniques
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green