[The effect of periodontal initial therapy on chronic periodontitis and subgingival periodontal pathogen].
OBJECTIVE
To evaluate the effect of periodontal initial therapy on clinical parameters and subgingival periodontal pathogen in patients with chronic periodontitis.


METHODS
One hundred and twenty patients with chronic periodontitis were included. Probing depth (PD), attachment loss (AL), plaque index (PLI) and gingival index (GI) were evaluated at baseline and after-initial therapy. P.g and A.a in subgingival plaque were investigated by real-time PCR. Data was statistically analyzed by SAS6.12 software for Student's t test.


RESULTS
The PD, AL, PLI and GI were significantly decreased after periodontal initial therapy (P<0.01), and meanwhile the ratio of P.g versus total bacteria was significantly decreased after-initial therapy (P<0.05). However, the change of ratio of A.a versus total bacteria was not significant (P>0.05).


CONCLUSIONS
Periodontal initial therapy could effectively control the inflammation of chronic periodontitis, and decrease the ratio of P.g in subgingival plaque.
Shu
Rong
R
Department of Periodontology, College of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China. shurong123@hotmail.com
Song
Zhong-chen
ZC
Ge
Lin-hua
LH
Gu
Jing-jing
JJ
Cheng
Lan
L
Xie
Yu-feng
YF
Li
Chao-lun
CL
Liu
Xiao-feng
XF
Liu
Da-li
DL
D055113:Chronic Periodontitis; D003773:Dental Plaque; D003774:Dental Plaque Index; D006801:Humans; D017622:Periodontal Attachment Loss; D010512:Periodontal Index; D010514:Periodontal Pocket; D010518:Periodontitis