Ionic cyclodextrins in ionic liquid matrices as chiral stationary phases for gas chromatography.
Ionic liquids (ILs) are used to dissolve ionic cyclodextrin (CD) derivatives to produce a new type of gas chromatographic chiral stationary phase. Compared to a previous study with neutral cyclodextrin chiral selectors, the new ionic liquid-based stationary phase exhibits broader enantioselectivities, up to seven times higher efficiencies, and greater thermal stabilities. When compared to the analogous commercial column with polysiloxane matrix, it exhibits different enantioselectivities, more symmetric peak shapes and some complementary enantioseparations. The most profound separation enhancements are usually found for more polar analytes.
Huang
Ke
K
University of Texas at Arlington, Department of Chemistry and Biochemistry, Arlington, TX 76019, USA.
Zhang
Xiaotong
X
Armstrong
Daniel W
DW
D002849:Chromatography, Gas / Q000379:methods*; D052578:Ionic Liquids / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature; D013818:Thermogravimetry; D047392:beta-Cyclodextrins / Q000737:chemistry*
D052578:Ionic Liquids; D047392:beta-Cyclodextrins