Limited utility of culture for Mycoplasma pneumoniae and Chlamydophila pneumoniae for diagnosis of respiratory tract infections.
We assessed the utility of culture for Mycoplasma pneumoniae and Chlamydophila pneumoniae to diagnose respiratory tract infections. Compared to PCR and IgM serology, culture was less sensitive and had extremely low yield. Culture is not recommended for these pathogens, and this method should be eliminated from routine practice.
She
Rosemary C
RC
ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108, USA. rosemary.she-bender@hsc.utah.edu
Thurber
Andy
A
Hymas
Weston C
WC
Stevenson
Jeffery
J
Langer
Janine
J
Litwin
Christine M
CM
Petti
Cathy A
CA
D000907:Antibodies, Bacterial / Q000097:blood; D001431:Bacteriological Techniques / Q000379:methods*; D023521:Chlamydophila Infections / Q000175:diagnosis* / Q000382:microbiology; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000235:genetics; D006801:Humans; D007118:Immunoassay / Q000379:methods; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis* / Q000382:microbiology; D016133:Polymerase Chain Reaction / Q000379:methods; D012141:Respiratory Tract Infections / Q000382:microbiology*; D012680:Sensitivity and Specificity
D000907:Antibodies, Bacterial; D004269:DNA, Bacterial