Recurrent endometrial stromal sarcoma: treatment with a progestin and gonadotropin releasing hormone agonist.
Endometrial stromal sarcoma (ESS) formerly classified as low-grade endometrial stromal sarcoma is a rare uterine malignancy with a good prognosis despite a tendency to recur. Primary surgical management for ESS includes total abdominal hysterectomy and bilateral salpingo-oophorectomy. Patients with ESS have long disease-free survival rates when treated with primary surgical therapy, but nearly fifty percent of these patients will recur. We present the case of a patient with recurrent ESS who had an excellent response to combined therapy with megestrol and leuprolide.
Dupont
Nefertiti Chianti
NC
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Irvine College of Medicine, Orange, CA 92868, USA.
Disaia
Philip John
PJ