title: Hemodynamic changes during weaning: can we assess and predict cardiac-related weaning failure by transthoracic echocardiography?
abstract: Cardiac-related failure of weaning from mechanical ventilation is an important reason for prolonged mechanical ventilation, intensive care unit treatment, and increased morbidity and mortality. When transthoracic echocardiography (TTE) is routinely performed before a weaning trial, patients at high risk of cardiac-related failure can be detected by low left ventricular (LV) ejection fraction, diastolic dysfunction, and elevated LV filling pressure. During the weaning trial, a further increase of LV filling pressure and progression of diastolic failure can be observed by repeated TTE. Owing to certain limitations concerning patients and methodology, TTE cannot be employed in every patient and invasive hemodynamic monitoring is still mandatory in selected patients with repetitive weaning failure.
authors.affiliation: Medical Intensive Care Unit, General Hospital Celje, Oblakova 5, 3000 Celje, Slovenia. gorazd.voga@guest.arnes.si
authors.forename: Gorazd
authors.initials: G
authors.lastname: Voga
mesh_terms: D004452:Echocardiography; D006333:Heart Failure / Q000175:diagnosis* / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D015300:Ventilator Weaning / Q000379:methods*