Pancreas allograft thrombosis.
Thrombosis of the transplanted pancreas is a common and often catastrophic event. Predisposing factors include the hypercoagulable state of many patients with diabetic renal failure, preservation-related graft endothelial injury, and low-velocity venous flow. Clinical management includes optimization of modifiable risk factors, controlled anticoagulation, graft monitoring, and early therapeutic intervention.
Muthusamy
Anand S R
AS
Oxford Transplant Centre, Churchill Hospital, Oxford, United Kingdom.
Giangrande
Paul L F
PL
Friend
Peter J
PJ
D000925:Anticoagulants / Q000627:therapeutic use; D001783:Blood Flow Velocity; D003928:Diabetic Nephropathies / Q000601:surgery; D004727:Endothelium / Q000473:pathology; D006801:Humans; D016035:Pancreas Transplantation / Q000009:adverse effects* / Q000706:statistics & numerical data; D010180:Pancreatectomy / Q000009:adverse effects; D013162:Splenic Vein / Q000601:surgery; D013927:Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D014184:Transplantation, Homologous / Q000473:pathology
D000925:Anticoagulants