title: A 22-year-old Australian woman with atypical subacute sclerosing panencephalitis diagnosed at postmortem.
abstract: Measles remains a significant global health problem. Despite the decline in measles prevalence in Australia following the implementation of a national vaccination program, challenges surrounding this disease remain. This report describes a 22-year-old woman who presented with coordination loss, tremor, choreiform movements and marked visual blurring, and her condition rapidly deteriorated to coma and death. Antemortem investigations did not yield a unifying diagnosis. Postmortem examination provided a diagnosis of subacute sclerosing panencephalitis. This patient had a rare neurological complication of measles infection, and her condition is remarkable for the atypical clinical presentation.
authors.affiliation: Department of Anatomical Pathology, Section of Neuropathology, Royal Perth Hospital, Perth, Western Australia 6001, Australia.
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Fabian
authors.forename: Hwei-Yee
authors.initials: HY
authors.lastname: Lee
authors.forename: Julia Lee
authors.initials: JL
authors.lastname: Keith-Rokosh
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: de Souza
authors.forename: Edward
authors.initials: E
authors.lastname: Stewart-Wynne
mesh_terms: D001315:Australia; D001344:Autopsy; D003128:Coma / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D008457:Measles / Q000150:complications / Q000473:pathology*; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D055815:Young Adult