Iron-catalyzed regio- and stereoselective addition of acid chlorides to alkynes.
An iron-catalyzed regio- and stereoselective addition of acid chlorides to alkynes has been described. The reaction utilizes an inexpensive iron catalyst system and it is suitable for the formation of a variety of bifunctional molecules. This is an inexpensive, regio-, stereoselective and atom-economical approach to beta-chloro-alpha,beta-unsaturated ketones from simple and readily available starting materials.
Wang
Bo
B
Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, PR China.
Wang
Shihua
S
Li
Pinhua
P
Wang
Lei
L