Thyrotoxic periodic paralysis (TPP) in a 28-year-old sudanese man started on prednisone.
Thyrotoxic periodic paralysis is a rare complication associated with hyperthyroidism. It is most common in the Asian population. We describe a case of a 28-year-old Sudanese man who presented with ascending lower extremity paralysis after treatment of hyperthyroidism with prednisone and methimazole. This case report reviews the literature looking at pathophysiology, causes, and treatment recommendations for this rare complication of hyperthyroidism.
Tessier
Joshua J
JJ
Iowa Lutheran Family Medicine Residency, Iowa Lutheran Hospital, Des Moines, Iowa City, IA, USA. tessiejj@ihs.org
Neu
Stacey K
SK
Horning
Kristin K
KK
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood* / Q000188:drug therapy; D007008:Hypokalemia / Q000097:blood / Q000188:drug therapy; D020514:Hypokalemic Periodic Paralysis / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D010243:Paralysis / Q000209:etiology; D011189:Potassium Chloride / Q000627:therapeutic use*; D011239:Prednisolone / Q000009:adverse effects* / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D000893:Anti-Inflammatory Agents; D011189:Potassium Chloride; D011239:Prednisolone; D011433:Propranolol