title: Identification of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B.
authors.affiliation: Abteilung Chemische Biologie, Max-Planck-Institut für molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
authors.forename: Viktor V
authors.initials: VV
authors.lastname: Vintonyak
authors.forename: Karin
authors.initials: K
authors.lastname: Warburg
authors.forename: Holger
authors.initials: H
authors.lastname: Kruse
authors.forename: Stefan
authors.initials: S
authors.lastname: Grimme
authors.forename: Katja
authors.initials: K
authors.lastname: Hübel
authors.forename: Daniel
authors.initials: D
authors.lastname: Rauh
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
mesh_terms: D001426:Bacterial Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D002942:Circular Dichroism; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000201:enzymology*; D017027:Protein Tyrosine Phosphatases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013141:Spiro Compounds / Q000737:chemistry; D053778:Thiazolidines / Q000737:chemistry
chemical_list: D001426:Bacterial Proteins; D004791:Enzyme Inhibitors; D007211:Indoles; D013141:Spiro Compounds; D053778:Thiazolidines; C456900:indolin-2-one; D017027:Protein Tyrosine Phosphatases