[Randomized trail of nasal synchronized intermittent mandatory ventilation compared with nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome].
OBJECTIVE
To compare the efficacy of nasal synchronized intermittent mandatory ventilation (nSIMV) and nasal continuous positive airway pressure (nCPAP) in preterm infants with respiratory distress syndrome (RDS).


METHODS
Fifty preterm infants with RDS who received pulmonary surfactant were randomized to nSIMV and nCPAP groups after extubation. Clinical signs, symptoms and blood gas results following nSIMV or nCPAP were compared in the two groups.


RESULTS
Compared with the nCPAP group, the nSIMV group had a lower incidence of failure respiratory support (24% vs 60%; P<0.05), a lower incidence of hypercarbonia (12% vs 40%; P<0.05) and a lower incidence of hypoxia (24% vs 36%; P<0.05).


CONCLUSIONS
nSIMV is more effective in respiratory support in preterm infants with RDS.
Gao
Wei-Wei
WW
Guangdong Provincial Women and Children's Hospital, Guangzhou 510010, China.
Tan
San-Zhi
SZ
Chen
Yun-Bin
YB
Zhang
Yong
Y
Wang
Yue
Y
D045422:Continuous Positive Airway Pressure / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007385:Intermittent Positive-Pressure Ventilation / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*