Bilateral prophylactic mastectomy in women with inherited risk of breast cancer--prevalence of pain and discomfort, impact on sexuality, quality of life and feelings of regret two years after surgery.
BACKGROUND
Mastectomy due to breast cancer is associated with chronic pain and a negative impact on sexuality. The purposes of the study were to analyze the prevalence of pain and discomfort in the breasts, impact on sexuality, quality of life, and feelings of regret after bilateral prophylactic mastectomy and immediate reconstruction with implants.


METHODS
Fifty-nine women operated 2004-2006 were included. A questionnaire was sent out two years after the procedure. Complications and re-operations were recorded.


RESULTS
Mean follow-up time was 29 months. 93% of patients answered the questionnaire. 69% reported pain and 71% discomfort in the breasts. Lost or much reduced sexual sensations were reported by 85% and enjoyment of sex was negatively impacted for 75% of patients. Quality of life was not affected and feelings of regret were almost non-existent.


CONCLUSIONS
It is important to inform women approaching this prophylactic procedure about the risk of having unwanted secondary effects.
Gahm
Jessica
J
Department of Molecular Medicine and Surgery, Section of Reconstructive Plastic Surgery, Karolinska University Hospital, SE-171 76 Stockholm, Sweden. jessica.gahm@karolinska.se
Wickman
Marie
M
Brandberg
Yvonne
Y
D000328:Adult; D000368:Aged; D001940:Breast / Q000601:surgery; D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control*; D002908:Chronic Disease; D004644:Emotions; D005260:Female; D006801:Humans; D016015:Logistic Models; D016462:Mammaplasty / Q000009:adverse effects / Q000523:psychology; D008408:Mastectomy / Q000009:adverse effects* / Q000523:psychology*; D008875:Middle Aged; D010146:Pain / Q000453:epidemiology*; D011788:Quality of Life / Q000523:psychology*; D019529:Sexuality / Q000523:psychology*; D011795:Surveys and Questionnaires