title: Intracranial arterial dissections in ischemic stroke assessed by 3D rotational angiography.
abstract: BACKGROUND
  Dissections involving intracranial arteries are sometimes difficult to assess using conventional digital subtraction angiography (DSA). We evaluated the value of three-dimensional rotational angiography (3D-RA) for the assessment of intracranial arterial dissections (ICADs).
  
  
  METHODS
  The subjects were 39 patients (26 males, 13 females; average age 50+/-15years) who were diagnosed as having ICADs and who underwent both DSA and 3D-RA in our hospital between April 1999 and March 2005. We retrospectively compared 3D-RA images to conventional DSA images in a blinded manner with respect to double lumen sign, pearl and string sign, string sign, and aneurysmal dilatation. On the basis of the caliber size of the artery affected by dissections, we divided patients into two groups: smaller artery group (S group) and larger artery group (L group).
  
  
  RESULTS
  The detection rate of double lumen sign with 3D-RA (79%) was significantly higher than with conventional DSA (18%; P<0.001). Reliable findings of arterial dissections (double lumen sign and/or pearl and string sign) were observed more often with 3D-RA (90%) than with conventional DSA (36%; P<0.001). In S group, the double lumen sign was detected only with 3D-RA.
  
  
  CONCLUSIONS
  3D-RA allows increased conspicuity of ICADs findings with conventional DSA, especially in smaller-caliber intracranial arteries.
authors.affiliation: Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan. shoji-matsumoto@384.jp
authors.forename: Shoji
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Takada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yasaka
authors.forename: Junji
authors.initials: J
authors.lastname: Kasuya
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamada
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Naritomi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Minematsu
mesh_terms: D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000000981:diagnostic imaging; D015901:Angiography, Digital Subtraction / Q000379:methods*; D002545:Brain Ischemia / Q000150:complications / Q000473:pathology*; D002533:Cerebral Angiography / Q000379:methods*; D002536:Cerebral Arteries / Q000473:pathology*; D002544:Cerebral Infarction / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D020765:Intracranial Arterial Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000209:etiology / Q000473:pathology*