title: Recruiting American Indian women for a genetic epidemiology study.
abstract: Due to previous negative experiences, some American Indian communities are distrustful of research in general and genetic research in particular. The Turtle Mountain Community College was awarded a National Institutes of Health (NIH) grant with 3 aims: (1) to study possible genetic influences on pre-eclampsia, (2) to encourage tribal college students to consider biomedical careers and (3) to develop the local research infrastructure. Retrospectively identified case (91) and control (188) participants were recruited into Phase I over a 3-year period and additional participants (71) were concurrently recruited from a prenatal clinic into a prospective case/control study, Phase II. This paper describes some of the challenges and solutions we encountered in the process of recruiting American Indian participants into a genetic epidemiologic study.
authors.affiliation: Turtle Mountain Community College, Belcourt, ND 58367, USA.
authors.forename: M
authors.initials: M
authors.lastname: Nadeau
authors.forename: L
authors.initials: L
authors.lastname: Best
mesh_terms: D000293:Adolescent; D001294:Attitude to Health / Q000208:ethnology*; D016022:Case-Control Studies; D017321:Clinical Trials, Phase I as Topic; D017322:Clinical Trials, Phase II as Topic; D003299:Cooperative Behavior; D016021:Epidemiologic Studies; D005260:Female; D006302:Health Services Research / Q000458:organization & administration; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D017720:Molecular Epidemiology; D010358:Patient Participation; D018579:Patient Selection; D011225:Pre-Eclampsia / Q000453:epidemiology / Q000235:genetics*; D011247:Pregnancy; D011446:Prospective Studies; D013334:Students; D014481:United States / Q000453:epidemiology