[Effects of electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on cardiac function in acute myocardial ischemia rabbits].
OBJECTIVE
To observe the effect of electroacupuncture (EA) of "Neiguan" (PC 6) and "Taichong" (LR 3) on mechnical activities of the heart in acute myocardial ischemia (AMI) rabbits.


METHODS
Fifty chinchilla rabbits were randomized into normal control, model, EA-PC 6, EA-LR 3 and non-acupoint groups (n = 8/group). AMI model was duplicated by intravenous injection (femoral vein) of posterior pituitrin (3 U/kg). The maximal ascending velocity (+ dp/dt max), maximal descending velocity (-dp/dt max) and left ventricular systolic pressure (LVSP) of the heart were recorded by using Biopac Bio-signal system. EA (1 mA, 2 Hz) was applied to PC 6, LR 3 and non-acupoint for 10 min.


RESULTS
Compared with normal control group, + dp/dt max, - dp/dt max and LVSP of the heart in model group reduced significantly (P < 0.01); while in comparison with model group, left ventricular + dp/dt max and - dp/dt max at 10 min after EA in EA-PC 6 and EA-LR 3 groups increased markedly (P < 0.01), and LVSP of EA-PC 6 group increased remarkably (P < 0.05). No significant differences were found between EA-non-acupoint group and model group in the above-mentioned 3 indexes (P > 0.05).


CONCLUSIONS
Both EA of PC 6 and LR 3 points can improve AMI induced reduction of the left ventricular myocardial mechanical activities in the rabbit, and the therapeutic effect of EA-PC 6 is superior to that of EA-LR 3.
Cai
Rong-lin
RL
Research Institute of Acu-moxibustion and Meridians, Anhui College of Chinese Medicine, China. ronglincai@163.com
Hu
Ling
L
Wang
Ke-ming
KM
Wu
Zi-jian
ZJ
Chen
Ye-nong
YN
Long
Di-he
DH
He
Lu
L
Liu
Jing
J
D015669:Acupuncture Points; D000208:Acute Disease / Q000628:therapy; D000818:Animals; D001794:Blood Pressure; D004195:Disease Models, Animal; D015671:Electroacupuncture; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000503:physiopathology* / Q000628:therapy*; D011817:Rabbits; D011897:Random Allocation; D051381:Rats