title: Usefulness of endoscopic ultrasonography in preoperative gastric cancer staging: diagnostic yield and therapeutic impact.
abstract: OBJECTIVE
  To evaluate the diagnostic yield of endoscopic ultrasonography in loco-regional staging of gastric cancer in our medium and to determine the impact of this technique on later therapeutic management.
  
  
  METHODS
  This is a retrospective study carried out on patients histologically diagnosed with gastric adenocarcinoma who had been referred for endoscopic ultrasonographic examination. The technique results were compared with those obtained from surgical samples and/or from exploratory laparoscopy- laparotomy. We compared the initial therapeutic decision based on conventional diagnostic techniques with the final therapeutic management based on the endoscopic ultrasonography results.
  
  
  RESULTS
  Forty-six patients with gastric adenocarcinoma were included in the study (a reference exploration was available in 36 cases). Diagnostic precision was 70% in stage T, while in stages T1, T2, T3 y T4 was 100, 38, 82, and 100%, respectively. The sensitivity and specificity to differentiate T1-2 from T3-4 was 94 and 85%, respectively. We could not identify factors associated with obtaining a correct diagnosis in staging T. Diagnostic precision was 72% for stage N (N0: 58%; Nx 88%). The presence of free perigastric fluid was identified in 7 cases; the presence of peritoneal carcinomatosis was later confirmed in 5 of these. The result of endoscopic ultrasonography led to a modification in the subsequent therapeutic management in 13 patients (28%).
  
  
  CONCLUSIONS
  Endoscopic ultrasonography is a useful technique for loco-regional staging of gastric adenocarcinoma, which may have important implications in the therapeutic management of these patients.
authors.affiliation: Department of Gastroenterology, Hospital Virgen de la Salud, Toledo, Spain. arepiso@sescam.jccm.es
authors.forename: A
authors.initials: A
authors.lastname: Repiso
authors.forename: R
authors.initials: R
authors.lastname: Gómez-Rodríguez
authors.forename: R
authors.initials: R
authors.lastname: López-Pardo
authors.forename: M M
authors.initials: MM
authors.lastname: Lombera
authors.forename: M
authors.initials: M
authors.lastname: Romero
authors.forename: A
authors.initials: A
authors.lastname: Aranzana
authors.forename: S
authors.initials: S
authors.lastname: Abad
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez-Merlo
authors.forename: L
authors.initials: L
authors.lastname: López
authors.forename: J M
authors.initials: JM
authors.lastname: Carboles
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy