title: High incidence of absent nerve conduction in older patients with bilateral carpal tunnel syndrome.
abstract: BACKGROUND
  Carpal tunnel syndrome has been reported by some to have a less satisfactory outcome in older patients following surgery. However, this impression is not supported by other investigators but no objective explanation has been suggested for these differences. In our department, such patients are routinely treated with night wrist splints and, if this is unsatisfactory, they are investigated with nerve conduction studies prior to surgery.
  
  
  METHODS
  This paper reports the neurophysiological outcome in a young (< 40 years of age) and an older (> 60 years of age) group of patients with clinical bilateral carpal tunnel syndrome who did not benefit from splints.
  
  
  RESULTS
  The results showed that both the motor and sensory conduction speeds are significantly lower in the older age group. More importantly in the older group, half had one or more hands where the sensory conduction was absent. In four out of these 10 patients this finding was bilateral and three patients had unilateral absent motor conduction. In the younger group, no patient had absent conduction.
  
  
  CONCLUSIONS
  Poor surgical outcome in some older patients may be because of irreversibly damaged nerves prior to surgery and pre-operative neurophysiology is, therefore, recommended both for clinical and medicolegal reasons.
authors.affiliation: Department of Orthopaedic Surgery, Guy's and St Thomas' Hospitals, London, UK. bo@manusmedical.com
authors.forename: Bo
authors.initials: B
authors.lastname: Povlsen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D002349:Carpal Tunnel Syndrome / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006225:Hand / Q000294:innervation*; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000293:injuries / Q000503:physiopathology; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology*; D011379:Prognosis; D011984:Sensory Receptor Cells / Q000502:physiology; D013165:Splints