[Uncommon complication of anticoagulant therapy: pituitary hemorrhage].
Pituitary apoplexy is well known as the first manifestation of pituitary tumour. Conversely, haemorrhage of a pituitary adenoma, revealed by anticoagulant therapy, is very uncommon. Two weeks after initiation of anticoagulant therapy for a deep venous thrombosis, an 83-year-old woman presented with intracranial hypertension and blindness. CT-scan revealed pituitary hematoma within a large adenoma. Three months after surgery, partial visual defect persisted in association with panhypopituitarism. When pituitary disorder is known, hemorrhage risk should be taken into account in the prescription of anticoagulant therapy.
Dupuy
O
O
Service d'endocrinologie et maladies métaboliques, HIA Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France. Olivier.dupuy@santarm.fr
Bordier
L
L
Galzin
A
A
Le Berre
J-P
JP
Mayaudon
H
H
Bauduceau
B
B
D000236:Adenoma / Q000150:complications*; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D010900:Pituitary Diseases / Q000139:chemically induced*; D010911:Pituitary Neoplasms / Q000150:complications*
D000925:Anticoagulants