[A case report of familial AVM].
Genetic analysis of the familials of patients with arteriovenous malformation (AVM) has a significant potential to reveal the etiology of this disease, although neither the detailed etiology nor pathogenesis of AVM has been fully elucidated to date. While a history of AVM is apparent in 2% of stroke patients, familial occurrence of AVM is very rare. We describe an interesting familial case of AVM. This also represents a rare pattern of familial occurrence in that patients are not likely hereditary hemorrhagic telangiectasia (HHT). There is a possibility that such familial AVMs are associated with unknown genes other than HHT genes.
Wajima
Daisuke
D
Department of Neurosurgery, University of Nara Medical Graduate School, Kashihara-city, Nara, Japan.
Takeshima
Yasuhiro
Y
Tamura
Kentaro
K
Motoyama
Yasushi
Y
Hirabayashi
Hidehiro
H
Nakase
Hiroyuki
H
D005190:Family; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000235:genetics*; D008297:Male; D008875:Middle Aged