title: Structural analysis of lipopolysaccharides from Gram-negative bacteria.
abstract: This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.
authors.affiliation: Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. kabanovd1@rambler.ru
authors.forename: D S
authors.initials: DS
authors.lastname: Kabanov
authors.forename: I R
authors.initials: IR
authors.lastname: Prokhorenko
mesh_terms: D016207:Cytokines / Q000378:metabolism; D005227:Fatty Acids / Q000737:chemistry; D006090:Gram-Negative Bacteria / Q000737:chemistry*; D006801:Humans; D008050:Lipid A / Q000737:chemistry; D008070:Lipopolysaccharides / Q000737:chemistry*; D009844:Oligosaccharides / Q000737:chemistry
chemical_list: D016207:Cytokines; D005227:Fatty Acids; D008050:Lipid A; D008070:Lipopolysaccharides; D009844:Oligosaccharides