title: Spinal compression by brown tumor in two patients with chronic kidney allograft failure on maintenance hemodialysis.
abstract: Brown tumors with non-neoplastic process are noticed in patients with end-stage renal disease suffering from a severe form of secondary hyperparathyroidism. Herein, we report a patient with chronic kidney allograft failure returned back to hemodialysis who experienced manifestations of cauda equina compression secondary to a lumbar brown tumor. Also, we had another patient on hemodialysis with a demineralized lesion affecting the cervical vertebrae. Although brown tumor is a rare complication, these two cases highlighted the importance of neurological symptoms in uremic patients. Spinal decompression surgery, in order to alleviate pressure on neurological structures, together with subtotal parathyroidectomy, were highly indicated.
authors.affiliation: Urology and Nephrology Center, Mansoura University, Mansoura, Egypt. ogheith@yahoo.com
authors.forename: Osama
authors.initials: O
authors.lastname: Gheith
authors.forename: Hesham
authors.initials: H
authors.lastname: Ammar
authors.forename: Ahmed
authors.initials: A
authors.lastname: Akl
authors.forename: Ahmed
authors.initials: A
authors.lastname: Hamdy
authors.forename: Mohamed
authors.initials: M
authors.lastname: El-Saeed
authors.forename: Tamer
authors.initials: T
authors.lastname: El-Salamouny
authors.forename: Mohamed Adel
authors.initials: MA
authors.lastname: Bakr
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ghoneim
mesh_terms: D000328:Adult; D002420:Cauda Equina; D002908:Chronic Disease; D019299:Decompression, Surgical; D005260:Female; D006084:Graft Rejection; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D016105:Parathyroidectomy; D006435:Renal Dialysis / Q000009:adverse effects*; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery