Annotating conserved and novel features of primate transcriptomes using sequencing.
Recent high-throughput sequencing of chimpanzee brain and liver transcriptomes published in Genome Biology reveals multiple transcripts lost in the human genome and highlights the incompleteness of primate genome annotations.
Khaitovich
Philipp
P
Partner Institute for Computational Biology, Chinese Academy of Sciences, 320 Yue Yang Road, 200031 Shanghai, China. khaitovich@eva.mpg.de
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism; D017124:Conserved Sequence / Q000235:genetics*; D005091:Exons / Q000235:genetics*; D020869:Gene Expression Profiling; D006801:Humans; D008099:Liver / Q000378:metabolism; D058977:Molecular Sequence Annotation; D002679:Pan troglodytes / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*