Expression of E- and N-cadherin and CD44 in endometrium and hydrosalpinges from infertile women.
In this prospective comparative study, compared with fertile control subjects (n = 12), infertile patients with hydrosalpinx (n = 18) had lower E-cadherin and a trend toward decreased N-cadherin H-scores in the endometrium (3.6 ± 0.6 vs. 2.4 ± 0.8 and 0.57 ± 1.0 vs. 0.52 ± 0.5, respectively). In hydrosalpinx, epithelial N-cadherin expression was discontinuous and disappeared in atrophic patches.
Poncelet
Christophe
C
Department of Obstetrics and Gynecology, CHU Jean Verdier, Assistance Publique-Hôpitaux de Paris, Bondy, France. christophe.poncelet@jvr.aphp.fr
Cornelis
Françoise
F
Tepper
Maryline
M
Sauce
Emmanuel
E
Magan
Nathalie
N
Wolf
Jean Philippe
JP
Ziol
Marianne
M
D015703:Antigens, CD / Q000378:metabolism*; D001284:Atrophy / Q000378:metabolism; D001706:Biopsy; D015820:Cadherins / Q000378:metabolism*; D016022:Case-Control Studies; D004717:Endometrium / Q000378:metabolism* / Q000473:pathology; D005184:Fallopian Tube Diseases / Q000378:metabolism* / Q000473:pathology; D005187:Fallopian Tubes / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D018960:Hyaluronan Receptors / Q000378:metabolism*; D007247:Infertility, Female / Q000378:metabolism* / Q000473:pathology
D015703:Antigens, CD; C497483:CD44 protein, human; C050361:CDH2 protein, human; D015820:Cadherins; D018960:Hyaluronan Receptors