title: Maternal and perinatal outcomes of dengue in PortSudan, Eastern Sudan.
abstract: OBJECTIVE
  To investigate maternal and perinatal outcomes (maternal death, preterm delivery, low birth weight and perinatal mortality) of dengue at PortSudan and Elmawani hospitals in the eastern Sudan.
  
  
  METHODS
  This was a retrospective Cohort study where medical files of women with dengue were reviewed.
  
  
  RESULTS
  There were 10820 deliveries and 78 (0.7%) pregnant women with confirmed dengue IgM serology at the mean (SD) gestational age of 29.4(8.2) weeks. While the majority of these women had dengue fever (46, 58.9%), hemorrhagic fever and dengue shock syndrome were the presentations in 18 (23.0%) and 12, (15.3%) of these women, respectively. There were 17(21.7%) maternal deaths. Fourteen (17.9%) of these 78 women had preterm deliveries and 19 (24.3%) neonates were admitted to neonatal intensive care unit. Nineteen (24.3%) women gave birth to low birth weight babies. There were seven (8.9%) perinatal deaths. Eight (10.2%) patients delivered by caesarean section due to various obstetrical indications.
  
  
  CONCLUSIONS
  Thus dengue has poor maternal and perinatal outcomes in this setting. Preventive measures against dengue should be employed in the region, and more research on dengue during pregnancy is needed.
authors.affiliation: Faculty of Medicine, University of Khartoum, Khartoum, Sudan. ishagadam@hotmail.com
authors.forename: Ishag
authors.initials: I
authors.lastname: Adam
authors.forename: Ammar M
authors.initials: AM
authors.lastname: Jumaa
authors.forename: Hagir M
authors.initials: HM
authors.lastname: Elbashir
authors.forename: Mubarak S
authors.initials: MS
authors.lastname: Karsany
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D015331:Cohort Studies; D003715:Dengue / Q000276:immunology / Q000401:mortality* / Q000635:transmission* / Q000821:virology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D008428:Maternal Mortality; D054238:Perinatal Mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology / Q000401:mortality* / Q000821:virology; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013397:Sudan; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral