Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs.
Recently in Nature Biotechnology, Rodin et al. (2010), Melkoumian et al. (2010), and Villa-Diaz et al. (2010) described defined, nonxenogenic substrates that support long-term self-renewal of human embryonic stem cells (hESCs). Used in conjunction with defined media, these substrates will facilitate expansion of hESCs for therapeutic applications.
Azarin
Samira M
SM
Department of Chemical & Biological Engineering, University of Wisconsin-Madison, WI 53706, USA.
Palecek
Sean P
SP