Bioactive xanthones from the stems of Cratoxylum formosum ssp. pruniflorum.
Six new compounds, pruniflorones M-R (1-6), together with 19 known compounds (7-25) were isolated from the stems of Cratoxylum formosum ssp. pruniflorum. The structures of the new compounds were established on the basis of extensive spectroscopic data interpretation. In addition, their RXRalpha transcriptional activities were evaluated using an in vitro assay.
Duan
Ying-hui
YH
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.
Dai
Yi
Y
Wang
Guang-hui
GH
Zhang
Xue
X
Chen
Hai-feng
HF
Chen
Jie-bo
JB
Yao
Xin-sheng
XS
Zhang
Xiao-kun
XK
D000818:Animals; D002522:Chlorocebus aethiops; D028084:Clusiaceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D047490:Retinoid X Receptor alpha / Q000187:drug effects* / Q000378:metabolism; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D047490:Retinoid X Receptor alpha; D044004:Xanthones