Thyroid carcinoma showing thymus-like differentiation (CASTLE): case report with cytomorphology and review of the literature.
Thyroid carcinoma showing thymus-like differentiation (CASTLE) is a rare tumor of the thyroid gland or adjacent soft tissues of the neck. Given the comparatively good prognosis of CASTLE, it is crucial to distinguish this neoplasm from other more aggressive thyroid neoplasms that can have similar or overlapping cytomorphological features. However, there is little information about the cytomorphology of CASTLE available in the literature. Here we report the cytomorphology and histology of thyroid CASTLE in a 52-year-old woman and present a review of the literature.
Youens
Kenneth E
KE
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA. kenneth.youens@duke.edu
Bean
Sarah M
SM
Dodd
Leslie G
LG
Jones
Claudia K
CK
D002449:Cell Aggregation; D002454:Cell Differentiation; D002843:Chromatin / Q000473:pathology; D003584:Cytological Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D013950:Thymus Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology*
D002843:Chromatin