Seroprevalence of hepatitis B surface antigen, antibodies to the hepatitis C virus, and human immunodeficiency virus in a hospital-based population in jaipur, rajasthan.
BACKGROUND
Hepatitis B, hepatitis C, and HIV infections are a serious global and public health problem. To assess the magnitude and dynamics of disease transmission and for its prevention and control, the study of its seroprevalence is important. A private hospital catering to the needs of a large population represents an important center for serological surveys. Available data, at Rajasthan state level, on the seroprevalence of these bloodborne pathogens is also very limited.


OBJECTIVE
A study was undertaken to estimate the seroprevalence of hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C (anti-HCV Ab) and human immunodeficiency virus (anti-HIV Ab) in both the sexes and different age groups in a hospital-based population in Jaipur, Rajasthan.


METHODS
Serum samples collected over a period of 14 months from patients attending OPDs and admitted to various IPDs of Fortis Escorts Hospital, Jaipur, were subjected within the hospital-based lab for the detection of HBsAg and anti-HCV Ab and anti-HIV Ab using rapid card tests. This was followed by further confirmation of all reactive samples by a microparticle enzyme immunoassay (Abbott AxSYM) at Super Religare Laboratories (formerly SRL Ranbaxy) Reference Lab, Mumbai.


RESULTS
The seroprevalence of HBsAg was found to be 0.87%, of anti-HCV Ab as 0.28%, and of anti-HIV Ab as 0.35%.


CONCLUSIONS
The study throws light on the magnitude of viral transmission in the community in the state of Rajasthan and provides a reference for future studies.
Sood
Smita
S
Department of Laboratory Medicine, Fortis Escorts Hospital, Jaipur and Super Religare Laboratories (Formerly SRL Ranbaxy) Reference Lab, Mumbai, India.
Malvankar
Shirish
S