Structure of autophagy-related protein Atg8 from the silkworm Bombyx mori.
Autophagy-related protein Atg8 is ubiquitous in all eukaryotes. It is involved in the Atg8-PE ubiquitin-like conjugation system, which is essential for autophagosome formation. The structures of Atg8 from different species are very similar and share a ubiquitin-fold domain at the C-terminus. In the 2.40 A crystal structure of Atg8 from the silkworm Bombyx mori reported here, the ubiquitin fold at the C-terminus is preceded by two additional helices at the N-terminus.
Hu
Chen
C
Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, People's Republic of China.
Zhang
Xuan
X
Teng
Yan Bin
YB
Hu
Hai Xi
HX
Li
Wei Fang
WF
D000595:Amino Acid Sequence; D000818:Animals; D001343:Autophagy; D012831:Bombyx / Q000737:chemistry* / Q000166:cytology; D018360:Crystallography, X-Ray; D019476:Insect Proteins / Q000737:chemistry*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D017510:Protein Folding; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D019476:Insect Proteins