Magnetic tweezers for the study of DNA tracking motors.
Single-molecule manipulation methods have opened a new vista on the study of molecular motors. Here we describe the use of magnetic traps for the investigation of the mechanism of DNA based motors, in particular helicases and translocases.
Manosas
Maria
M
Laboratoire de Physique Statistique, Ecole Normale Superieure, Université Paris Diderot, Paris, France.
Meglio
Adrien
A
Spiering
Michelle M
MM
Ding
Fangyuan
F
Benkovic
Stephen J
SJ
Barre
François-Xavier
FX
Saleh
Omar A
OA
Allemand
Jean François
JF
Bensimon
David
D
Croquette
Vincent
V
D004265:DNA Helicases / Q000737:chemistry* / Q000378:metabolism; D008280:Magnetics / Q000295:instrumentation / Q000379:methods; D000226:Mitochondrial ADP, ATP Translocases / Q000737:chemistry / Q000378:metabolism; D054159:Torsion, Mechanical
D000226:Mitochondrial ADP, ATP Translocases; D004265:DNA Helicases