Gestational trophoblastic disease: Regional perspective in Rio de Janeiro, Brazil.
OBJECTIVE
To give an overview of gestational trophoblastic disease in a referral center in Rio de Janeiro, Brazil.


METHODS
From January 1960 to December 2008, 4,290 registered patients were followed at the Gestational Trophoblastic Neoplasia Referral Center of Rio de Janeiro. All cases of complete and partial moles and of gestational trophoblastic neoplasia (GTN) were included and analyzed. Diagnosis, uterine evacuation, follow-up, chemotherapy and hysterectomy were reviewed in all patients.


RESULTS
The historical progression of molar pregnancy to GTN was 19.1%, decreasing to 11.6% in the last 9 years. The overall survival rate was 92.5% in patients with GTN.


CONCLUSIONS
Despite the intensive activities of the several Brazilian Referral Centers, governmental authorities do not consider gestational trophoblastic disease relevant and do not support any programs in its management. Official health data still omit vital statistics information on gestational trophoblastic disease.
Belfort
Paulo
P
Gestational Trophoblastic Neoplasia Referral Center, Santa Casa da Misericordia, Rio de Janeiro, Brazil. belfortp@uol.com.br
Baptista
Angela M
AM
Valle Filho
Oswaldo Cardoso
OC
D001938:Brazil / Q000453:epidemiology; D003131:Combined Modality Therapy / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D015994:Incidence; D011247:Pregnancy; D015995:Prevalence; D012017:Referral and Consultation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery