title: When fibroblasts MET iPSCs.
abstract: Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer.
authors.affiliation: Howard Hughes Medical Institute at Massachusetts General Hospital, Cancer Center, 185 Cambridge Street, Boston, MA 02114, USA.
authors.forename: Jose M
authors.initials: JM
authors.lastname: Polo
authors.forename: Konrad
authors.initials: K
authors.lastname: Hochedlinger