Attenuation in weight gain with high calcium- and dairy-enriched diets is not associated with taste aversion in rats: a comparison with casein, whey, and soy.
A systematic evaluation of the effects of calcium (Ca) and protein source on food intake and taste aversion (TA) in rats is lacking. The purpose of this research was twofold: (1) to determine if Sprague-Dawley rats display TA to standard rat chow supplemented with 2.4% Ca and (2) to determine if short (24-hour) and long-term (weekly) food intake and weight gain are altered when rats are given access to diets containing various protein sources (casein, whey, dairy, or soy). Rats were assigned to one of two diet groups to examine high (2.4%) versus low (0.67%) Ca or to one of four groups to examine taste preference of diets where the sole protein was one of casein, soy, whey, or complete dairy. A crossover design was used to ensure rats consumed all test diets. Food intake and behavioral sequence of satiety were measured. There was no TA to the 2.4% Ca diet or to any protein source. Food intake did not differ between the two Ca diets or between the four protein diets. The dairy diet attenuated weekly weight gain compared to all other diets except whey. Overall, this study suggests that the levels of Ca and types of protein used in previous work addressing changes in body weight in rats do not influence food intake or trigger TA.
Eller
Lindsay K
LK
Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary Calgary, Alberta, Canada.
Reimer
Raylene A
RA
D000818:Animals; D002136:Calcium, Dietary / Q000008:administration & dosage*; D002364:Caseins / Q000008:administration & dosage; D003611:Dairy Products; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage*; D004435:Eating; D005518:Food Preferences; D008297:Male; D008894:Milk Proteins / Q000008:administration & dosage; D051381:Rats; D017207:Rats, Sprague-Dawley; D012527:Satiation; D030262:Soybean Proteins / Q000008:administration & dosage; D013649:Taste; D015430:Weight Gain; D000067816:Whey Proteins
D002136:Calcium, Dietary; D002364:Caseins; D004044:Dietary Proteins; D008894:Milk Proteins; D030262:Soybean Proteins; D000067816:Whey Proteins