title: Clinical practice. The care of children with Down syndrome.
abstract: Down syndrome (DS) is one of the most common chromosomal abnormalities. Because of medical advances and improvements in overall medical care, the median survival of individuals with DS has increased considerably. This longer life expectancy requires giving the necessary care to the individual with DS over their total longer lifespan. DS medical guidelines are designed for the optimal care of the child in whom a diagnosis of DS has been confirmed. We present an overview of the most important issues related to children with DS based on the most relevant literature currently available.
authors.affiliation: Department of Pediatrics, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. weijerman@vumc.nl
authors.forename: Michel E
authors.initials: ME
authors.lastname: Weijerman
authors.forename: J Peter
authors.initials: JP
authors.lastname: de Winter
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D017028:Caregivers; D002648:Child; D015897:Comorbidity; D003695:Delivery of Health Care / Q000592:standards; D004314:Down Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality* / Q000628:therapy*; D005767:Gastrointestinal Diseases / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D006801:Humans; D008017:Life Expectancy; D010038:Otorhinolaryngologic Diseases / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D010290:Parents; D017410:Practice Guidelines as Topic / Q000592:standards; D015995:Prevalence; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D012307:Risk Factors; D014786:Vision Disorders / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*