title: Side effects of spiramycin masquerading as local anesthetic toxicity during labor epidural analgesia.
abstract: Significant fetal bradycardia occurred when a parturient receiving labor epidural analgesia experienced generalized numbness and tingling, a metallic taste and hot flushes. An emergent cesarean delivery under general anesthesia was performed with favorable outcomes for the mother and baby. The most likely source of the maternal symptoms was spiramycin, which was being administered for treatment of toxoplasmosis.
authors.affiliation: Département d'Anesthésie et Réanimation 4, CHU de Bordeaux, France.
authors.forename: B
authors.initials: B
authors.lastname: Julliac
authors.forename: H
authors.initials: H
authors.lastname: Théophile
authors.forename: M
authors.initials: M
authors.lastname: Begorre
authors.forename: B
authors.initials: B
authors.lastname: Richez
authors.forename: F
authors.initials: F
authors.lastname: Haramburu
mesh_terms: D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000779:Anesthetics, Local / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002585:Cesarean Section; D005260:Female; D046128:Fetal Therapies; D006801:Humans; D007743:Labor, Obstetric; D008508:Medication Errors; D010292:Paresthesia / Q000139:chemically induced / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D015572:Spiramycin / Q000009:adverse effects*; D013771:Tetralogy of Fallot / Q000601:surgery; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D015572:Spiramycin