[Macroglobulinosis cutis revealing Waldenström macroglobulinemia].
Waldenström macroglobulinemia is defined by a bone marrow lymphoplasmacytic infiltration associated with serum IgM monoclonal gammopathy. Specific properties of the IgM gammopathy induce the main clinical manifestations revealing the disease: hyperviscosity syndrome, autoimmune peripheral neuropathy, cryoglobulinemia or hemolysis, and exceptional skin deposit such as macroglobulinosis cutis that we here report. Physicians should be aware of these clinical manifestations to avoid diagnostic delay.
Rivière
E
E
Inserm U897, service de médecine interne et tropicale, hôpital Saint-André, CHU de Bordeaux, université Bordeaux 2 Victor-Segalen, 1, rue Jean-Burguet, 33000 Bordeaux, France. e.riviere@neuf.fr
Ghiringhelli
C B
CB
Peyrot
I
I
Lippa
N
N
Laffitte
A
A
Roger-Schmeltz
J
J
Milpied
B
B
Lepreux
S
S
Mercié
P
P
Longy-Boursier
M
M
D006801:Humans; D008297:Male; D008875:Middle Aged; D017444:Skin Diseases, Papulosquamous / Q000209:etiology*; D008258:Waldenstrom Macroglobulinemia / Q000175:diagnosis*