A validated method for standardization of the bark of Clerodendron serratum.
Clerodendron serratum (Linn.) Moon (family: Verbenaceae) is used in Indian System of Medicine for asthma and cough. In the present study the extract of the bark of the plant was standardized using oleanolic acid as a marker. Methanolic extracts of the bark were prepared after defatting. HPTLC was used to quantify oleanolic acid in the extract. Percentage content of oleanolic acid in the methanolic extract was determined as 1.2% in contrast to the raw material at 0.058 % (Percentage yield of the extract 4.8%).
Gantait
Arunava
A
School of Natural Product Studies, Jadavpur University, Kolkata 700032, India.
Roy
Payel
P
Nema
Neelesh Kumar
NK
Dutta
Pradip Kumar
PK
Mukherjee
Pulok Kumar
PK
D002855:Chromatography, Thin Layer / Q000379:methods* / Q000592:standards*; D032409:Clerodendrum / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry*; D012015:Reference Standards; D015203:Reproducibility of Results