title: Role of PET/CT in congenital histiocytosis.
abstract: Congenital Langerhans cell histiocytosis (LCH) is a rare, but often severe, form of LCH. Although a more benign single-system congenital LCH has been described, most cases present as multisystem disease with poorer prognosis and are often treated with systemic chemotherapy. Imaging plays a central role in diagnosis, initial staging and assessment of treatment response. PET/CT is increasingly utilized for pediatric LCH. We report a unique case with PET/CT used as an imaging tool in staging and evaluating treatment response in congenital multisystem LCH.
authors.affiliation: Department of Radiology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA. unnikaimal@gmail.com
authors.forename: Unni K
authors.initials: UK
authors.lastname: Udayasankar
authors.forename: Adina L
authors.initials: AL
authors.lastname: Alazraki
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Simoneaux
mesh_terms: D006646:Histiocytosis, Langerhans-Cell / Q000151:congenital* / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D049268:Positron-Emission Tomography; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging