title: Zolpidem poisoning in a cat.
abstract: Zolpidem (Stilnox) is a non-benzodiazepine hypnotic drug of the imidazopyridine class intended for treatment of insomnia in humans. A 16-year-old neutered cat, weighing 3.8 kg, was presented with sudden onset of stupor, disorientation, severe ataxia, vomiting and hypersalivation. Symptomatic treatment was given when ingestion of 1.25 mg/kg zolpidem (half of a 10-mg tablet) was confirmed, because no information on the efficacy and safety of the use of flumazenil in the treatment of zolpidem poisoning in cats has been published to date. As zolpidem is prescribed with increasing frequency in humans, the occurrence of accidental poisonings of pets is likely to increase.
authors.affiliation: Division of Infectious Diseases and Veterinary Epidemiology, Department of Clinical Sciences, Warsaw University of Life Sciences, 02-776 Warsaw, Poland. mczopowicz@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Czopowicz
authors.forename: O
authors.initials: O
authors.lastname: Szalus-Jordanow
authors.forename: T
authors.initials: T
authors.lastname: Frymus
mesh_terms: D000818:Animals; D000931:Antidotes / Q000627:therapeutic use; D001259:Ataxia / Q000139:chemically induced / Q000662:veterinary; D002371:Cat Diseases / Q000139:chemically induced* / Q000188:drug therapy; D002415:Cats; D005442:Flumazenil / Q000627:therapeutic use; D006948:Hyperkinesis / Q000139:chemically induced / Q000662:veterinary; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000506:poisoning*; D008297:Male; D011725:Pyridines / Q000506:poisoning*; D000077334:Zolpidem
chemical_list: D000931:Antidotes; D006993:Hypnotics and Sedatives; D011725:Pyridines; D005442:Flumazenil; D000077334:Zolpidem