Identification of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B.
Vintonyak
Viktor V
VV
Abteilung Chemische Biologie, Max-Planck-Institut für molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Warburg
Karin
K
Kruse
Holger
H
Grimme
Stefan
S
Hübel
Katja
K
Rauh
Daniel
D
Waldmann
Herbert
H
D001426:Bacterial Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D002942:Circular Dichroism; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000201:enzymology*; D017027:Protein Tyrosine Phosphatases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013141:Spiro Compounds / Q000737:chemistry; D053778:Thiazolidines / Q000737:chemistry
D001426:Bacterial Proteins; D004791:Enzyme Inhibitors; D007211:Indoles; D013141:Spiro Compounds; D053778:Thiazolidines; C456900:indolin-2-one; D017027:Protein Tyrosine Phosphatases