Sesquiterpenoids and other constituents from Senecio argunensis.
Three new sesquiterpenoids, isodauc-7(14)-en-6alpha,10beta-diol (1), 10beta-hydroxyisodauc-6-en-14-al (2), and (7S(*))-opposit-4(15)-en-1beta,7-diol (4), along with ten known compounds have been isolated from the aerial parts of Senecio argunensis. Their structures were established by means of detailed spectroscopic analysis including IR, HR-MS, and 1D NMR and 2D NMR data. The sesquiterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 4 exhibited weak antibacterial activity against Escherichia coli and Bacillus subtilis.
Xie
Wei-Dong
WD
Marine College, Shandong University at Weihai, Weihai, P. R. China. wdxie@sdu.edu.cn
Niu
Yu-Fang
YF
Lai
Peng-Xiang
PX
Row
Kyung-Ho
KH
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D012674:Senecio / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
C552663:(7S*)-opposit-4(15)-en-1beta ,7-diol; C552661:10beta-hydroxyisodauc-6-en-14-al; D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012717:Sesquiterpenes; C552662:isodauc-7(14)-en-6alpha,10beta-diol