Mitochondrial biogenesis: sorting mechanisms cooperate in ABC transporter assembly.
The assembly of proteins into the mitochondrial inner membrane had been thought to occur via several distinct pathways. A new study challenges this view and shows that the mitochondrial ABC transporter Mdl1 is assembled into the inner membrane in a modular fashion by two different pieces of machinery.
Webb
Chaille T
CT
Department of Biochemistry & Molecular Biology, Monash University, Clayton Campus, Melbourne 3800, Australia.
Lithgow
Trevor
T
D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000378:metabolism*; D007425:Intracellular Membranes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D008958:Models, Molecular
D018528:ATP-Binding Cassette Transporters