title: Review of heart-lung transplantation at Stanford.
abstract: Long-term survival after heart-lung transplantation was first achieved in 1981 at Stanford and a total of 217 heart-lung transplantations had been performed by June 2008. This review summarizes Stanford's cumulative experience with heart-lung transplantation, demonstrates the progress that has been made, and discusses past and persistent problems. Diagnostic tools and treatment options for infectious diseases and rejection have changed and patient survival markedly improved over the almost three decades. Eight patients lived longer than 20 years. Further options to treat infections and strategies to control bronchiolitis obliterans syndrome, the main causes of early and long-term mortality, respectively, are required to achieve routine long-term survival.
authors.affiliation: Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, USA.
authors.forename: Tobias
authors.initials: T
authors.lastname: Deuse
authors.forename: Ramachandra
authors.initials: R
authors.lastname: Sista
authors.forename: David
authors.initials: D
authors.lastname: Weill
authors.forename: Dolly
authors.initials: D
authors.lastname: Tyan
authors.forename: Francois
authors.initials: F
authors.lastname: Haddad
authors.forename: Gundeep
authors.initials: G
authors.lastname: Dhillon
authors.forename: Robert C
authors.initials: RC
authors.lastname: Robbins
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Reitz
mesh_terms: D000046:Academic Medical Centers; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D016041:Heart-Lung Transplantation / Q000379:methods*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D055815:Young Adult