RPPanalyzer: Analysis of reverse-phase protein array data.
CONCLUSIONS
RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data. Implemented plotting functions permit a quality control by monitoring data distribution and signal validity. Finally, the data can be visualized in heatmaps, boxplots, time course plots and correlation plots. RPPanalyzer is a flexible tool and tolerates a huge variety of different experimental designs.


BACKGROUND
The RPPAanalyzer is open source and freely available as an R-Package on the CRAN platform http://cran.r-project.org/.
Mannsperger
Heiko A
HA
Department of Molecular Genome Analysis, German Cancer Research Center Heidelberg, Germany. h.mannsperger@dkfz.de
Gade
Stephan
S
Henjes
Frauke
F
Beissbarth
Tim
T
Korf
Ulrike
U
D040081:Protein Array Analysis / Q000379:methods*; D040901:Proteomics / Q000379:methods; D012984:Software