title: International variations in outcomes from sedation protocol research: where are we at and where do we go from here?
abstract: In this article, sedation protocol research in the intensive care environment is critically examined, focusing upon the differences in outcomes from research conducted on mechanically ventilated patients in various countries. Limitations of the current research are discussed, with suggestions of how sedation protocol research may be conducted in future. Also, the monitoring of important clinical factors is discussed so that clinicians can assess the impact upon patients of changes to sedation management practices within their own ICU.
authors.affiliation: Alfred Hospital Intensive Care Unit, Prahran, Victoria, Australia. mar1oconnor2@yahoo.com.au
authors.forename: Mark
authors.initials: M
authors.lastname: O'Connor
authors.forename: Tracey
authors.initials: T
authors.lastname: Bucknall
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Manias
mesh_terms: D002985:Clinical Protocols; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D038622:Internationality; D012106:Research / Q000706:statistics & numerical data*; D012107:Research Design; D012121:Respiration, Artificial; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives