title: Department-related tasks and organ-targeted therapy in Fabry disease: an interdisciplinary challenge.
abstract: Fabry disease is a rare X-linked storage disorder leading to an accumulation of globotriaosylceramides in all cells carrying lysosomes. As the accumulation occurs in most organs, different medical specialties are involved in the diagnostics and therapy of Fabry disease. With this review of the 3 main specialties (cardiology, nephrology, and neurology) and, in addition, the adjacent specialties (ophthalmology and dermatology), we aim to discuss the division-related responsibilities and want to suggest an organ-related additional therapy besides enzyme replacement therapy.
authors.affiliation: Department of Medicine, Würzburg University Medical Center, Würzburg, Würzburg, Germany. weidemann_f@medizin.uni-wuerzburg.de
authors.forename: Frank
authors.initials: F
authors.lastname: Weidemann
authors.forename: Claudia
authors.initials: C
authors.lastname: Sommer
authors.forename: Thomas
authors.initials: T
authors.lastname: Duning
authors.forename: Ines
authors.initials: I
authors.lastname: Lanzl
authors.forename: Matthias
authors.initials: M
authors.lastname: Möhrenschlager
authors.forename: Dennis
authors.initials: D
authors.lastname: Naleschinski
authors.forename: Kathrin
authors.initials: K
authors.lastname: Arning
authors.forename: Ralf
authors.initials: R
authors.lastname: Baron
authors.forename: Markus
authors.initials: M
authors.lastname: Niemann
authors.forename: Frank
authors.initials: F
authors.lastname: Breunig
authors.forename: Roland
authors.initials: R
authors.lastname: Schaefer
authors.forename: Jörg
authors.initials: J
authors.lastname: Strotmann
authors.forename: Christoph
authors.initials: C
authors.lastname: Wanner
mesh_terms: D056947:Enzyme Replacement Therapy; D015785:Eye Diseases, Hereditary / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D000795:Fabry Disease / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D033183:Interdisciplinary Communication; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D010348:Patient Care Team; D006435:Renal Dialysis; D012873:Skin Diseases, Genetic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D013038:Specialization