Characterization of RD-114 virus isolated from a commercial canine vaccine manufactured using CRFK cells.
Recently, we found that several commercial pet vaccines were contaminated with an infectious endogenous retrovirus, RD-114-related virus. Here, we determined the entire nucleotide sequences of RD-114-related viruses isolated from CRFK cells and a vaccine manufactured using CRFK cells. These RD-114-related viruses were nearly identical to the authentic RD-114 virus.
Yoshikawa
Rokusuke
R
Laboratory of Signal Transduction, Department of Cell Biology, Institute for Virus Research, Kyoto University, 53 Shogoin-Kawaracho, Sakyo-ku, Kyoto 606-8507, Japan.
Sato
Eiji
E
Igarashi
Tatsuhiko
T
Miyazawa
Takayuki
T
D000818:Animals; D001483:Base Sequence; D002415:Cats; D002478:Cells, Cultured; D004279:DNA, Viral / Q000737:chemistry* / Q000235:genetics*; D004285:Dogs; D023061:Gene Order; D016679:Genome, Viral; D008969:Molecular Sequence Data; D012190:Retroviridae / Q000235:genetics* / Q000302:isolation & purification*; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014612:Vaccines
D004279:DNA, Viral; D014612:Vaccines