[Wegener's granulomatosis with anti-MPO c-ANCA revealed by uveitis].
Wegener's granulomatosis (WG) is a rare systemic necrotizing granulomatous vasculitis affecting small- to medium-sized vessels, associated with antineutrophil cytoplasm antibodies (ANCA), mainly anti-proteinase 3. Rarely, ANCA may be directed against myeloperoxidase. We report a 58-year-old woman who developed an uveitis as the presenting manifestation of Wegener's granulomatosis who highlight the usefulness of internist and ophthalmologist collaboration.
Mbéthé
G L Gaundong
GL
Service de médecine interne et maladies tropicales, pôle médecine urgences, hôpital Saint-André, université Victor-Segalen-Bordeaux-2, 33075 Bordeaux cedex, France. gaundong@yahoo.fr
Diéval
C
C
Lafitte
A
A
Roger-Schmeltz
J
J
Longy-Boursier
M
M
Mercié
P
P
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology*; D014605:Uveitis / Q000209:etiology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D009195:Peroxidase