title: How do proteins gain new domains?
abstract: A study of the contributions of different mechanisms of domain gain in animal proteins suggests that gene fusion is likely to be most frequent.
authors.affiliation: MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Marsh
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Teichmann
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D005091:Exons / Q000235:genetics; D006801:Humans; D007438:Introns / Q000235:genetics; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins