[Role of hyperlipidemia in cholelithiasis].
THE PURPOSE OF THE REVIEW: Was analyzed basic data on the contribution of blood serum lipids in the development of gallstone disease (GSD) in the world as well as in northern Russia, as well as the association of cholelithiasis and coronary heart disease (CHD).


BACKGROUND
Worldwide, there is suffer from cholelithiasis 10 to 15% of the population. In Russia, about 60% of adults have a lipid metabolism. According to some epidemiological and clinical studies, serum lipid profile did not differ in patients with and without gallstone disease, in others with cholelithiasis observed hyperlipidemia. In an epidemiological study in the unorganized population of Novosibirsk cholelithiasis occurs more frequently among men and women with lipid disorders. Indigenous peoples of the North Asian Russia this disease is less common than among the aliens, which was accompanied by a more moderate hyperlipidemia. There was a positive association between gallstone disease and coronary heart disease. Despite the fact that hypertriglyceridemia and hypo by a majority of authors are recognized risk factors for gallstone disease, a consensus on the contribution of blood serum lipids in the pathogenesis of gallstone no. Since gallstone mostly composed of cholesterol, probably need to examine the level of serum lipids in a moment of gallstones after this time can be obscured link hyperlipidemia and holelitgenesis.
Grigor'eva
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Maliutina
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Voevoda
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MI
D000328:Adult; D000367:Age Factors; D002769:Cholelithiasis / Q000097:blood / Q000209:etiology*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000209:etiology; D012737:Sex Factors
D008055:Lipids