[Radical complications of obesity].
Obesity increases overall morbidity mainly by the increased mass of fat tissues and by the hyperproduction of pro-inflammatory molecules by the abdominal tissue. Coronary artery disease, metabolic syndrome or diabetes mellitus are the main complications linked to the inflammatory low-grade syndrome whereas arthritis is linked to the adipocytes mass. Many other complications are associated with obesity: steato-hepatitis, glomerulo-sclerosis, digestive diseases such as gallstones, hypofertility, psychosocial dysfunction and depression and certain cancers. Obesity is also a risk factor for pregnancy and surgery. Most of these complications are reversible after a substantial weight loss.
Schlienger
Jean-Louis
JL
CHU Hautepierre-Strasbourg, service de médecine interne, endocrinologie et nutrition, 1, avenue Molière, BP 83049, 67098 Strasbourg cedex, France. jean-louis.schlienger@chru-strasbourg.fr
D001847:Bone Diseases / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology; D005234:Fatty Liver / Q000209:etiology; D006801:Humans; D007592:Joint Diseases / Q000209:etiology; D008659:Metabolic Diseases / Q000209:etiology; D009765:Obesity / Q000150:complications*; D012120:Respiration Disorders / Q000209:etiology