title: Effectiveness of 100% autologous serum drops in ocular surface disorders.
abstract: OBJECTIVE
  To evaluate the effectiveness of 100% autologous serum eye drops for the treatment of various ocular surface disorders.
  
  
  METHODS
  A descriptive prospective observational study carried out from May 2005 to February 2009 which included patients with ocular surface disorders treated with single-dose autologous serum eye drops. Treatment effectiveness was evaluated by using a clinical questionnaire in order to assess symptoms experienced by patients at the beginning and end of treatment.
  
  
  RESULTS
  A total of 15 patients (24 eyes) were evaluated. Clinical symptoms such as redness, burning, sharp pain and tired eyes improved in 100% of the patients, whereas dryness and sandy/gritty sensation improved in 92% of the patients. The overall improvement of clinical symptoms was worth the inconvenience of venipuncture according to 66.7% of the patients. Regarding tolerance for autologous serum eye drops, only one patient experienced some discomfort when using the single-dose eye drops.
  
  
  CONCLUSIONS
  The treatment with 100% autologous serum eye drops improved ocular symptoms for most patients.
authors.affiliation: Servicio de Farmacia, Hospital General Universitario de Alicante, Alicante, España.
authors.forename: A
authors.initials: A
authors.lastname: Jover Botella
authors.forename: J F
authors.initials: JF
authors.lastname: Márquez Peiró
authors.forename: K
authors.initials: K
authors.lastname: Márques
authors.forename: N
authors.initials: N
authors.lastname: Monts Cambero
authors.forename: J
authors.initials: J
authors.lastname: Selva Otaolaurruchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005128:Eye Diseases / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage; D011446:Prospective Studies; D044967:Serum
chemical_list: D009883:Ophthalmic Solutions