Paired neuron recordings in the prefrontal and inferotemporal cortices reveal that spatial selection precedes object identification during visual search.
We addressed the question of how we locate and identify objects in complex natural environments by simultaneously recording single neurons from two brain regions that play different roles in this familiar activity--the frontal eye field (FEF), an area in the prefrontal cortex that is involved in visual spatial selection, and the inferotemporal cortex (IT), which is involved in object recognition--in monkeys performing a covert visual search task. Although the monkeys reported object identity, not location, neural activity specifying target location was evident in FEF before neural activity specifying target identity in IT. These two distinct processes were temporally correlated implying a functional linkage between the end stages of "where" and "what" visual processing and indicating that spatial selection is necessary for the formation of complex object representations associated with visual perception.
Monosov
Ilya E
IE
Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. ilya.monosov@gmail.com
Sheinberg
David L
DL
Thompson
Kirk G
KG
D000818:Animals; D003463:Cues; D055724:Electrophysiological Phenomena; D000882:Haplorhini; D008297:Male; D009474:Neurons / Q000502:physiology*; D017397:Prefrontal Cortex / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*; D013647:Task Performance and Analysis; D013997:Time Factors; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*