[Propylthiouracil-induced multispecific antineutrophil cytoplasmic antibodies].
We report the case of a 28-year-old woman who presented with arthralgia during a treatment with propylthiouracil (PTU) for hyperthyroidism. Detection of antineutrophil cytoplasmic antibodies (ANCA) against myeloperoxidase, proteinase 3 and elastase led to suspect PTU induced vasculitis.
Servonnet
A
A
Service de biochimie, hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France. a_servonnet@yahoo.fr
Garcia-Hejl
C
C
Banal
F
F
Ramirez
J
J
Fontan
E
E
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D013956:Antithyroid Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011441:Propylthiouracil / Q000009:adverse effects*; D014657:Vasculitis / Q000139:chemically induced* / Q000276:immunology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D013956:Antithyroid Agents; D011441:Propylthiouracil