title: Changes in amniotic fluid index after maternal oral hydration in pregnancies with fetal gastroschisis: initial observations.
abstract: OBJECTIVE
  To evaluate the effect of maternal oral hydration on amniotic fluid index (AFI) in pregnancies with fetal gastroschisis.
  
  
  METHODS
  AFI was evaluated at 24-hour intervals, during 4 consecutive days, under a continuous maternal oral water hydration regimen, in singleton pregnancies with isolated fetal gastroschisis.
  
  
  RESULTS
  Nine pregnancies were examined at a mean gestational age of 31.6 weeks (+/-1.4) and mean maternal daily oral water intake was 3,437 (+/-810) ml. Mean AFI on days 0-3 were 13.2 (+/-2.9), 14.8 (+/-3.3), 14.5 (+/-3.1) and 14.8 (+/-2.6), respectively. AFI on day 0 was significantly lower compared to all the other 3 days (p = 0.01 and 0.02). Significant correlation was found in relative difference in AFI between day 0 and day 1 and gestational age (r = -0.67, p = 0.05) and the amount of water intake in the previous 24 h (r = 0.76, p = 0.02).
  
  
  CONCLUSIONS
  Maternal oral water hydration significantly increases AFI in pregnancies with isolated fetal gastroschisis.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital das Clínicas, São Paulo University Medical School, São Paulo, Brazil. mlbrizot@uol.com.br
authors.forename: Maria L
authors.initials: ML
authors.lastname: Brizot
authors.forename: Adolfo W
authors.initials: AW
authors.lastname: Liao
authors.forename: Roseli M
authors.initials: RM
authors.lastname: Nomura
authors.forename: Rossana P V
authors.initials: RP
authors.lastname: Francisco
authors.forename: Marcelo
authors.initials: M
authors.lastname: Zugaib
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000187:drug effects*; D005260:Female; D005440:Fluid Therapy; D020139:Gastroschisis / Q000150:complications*; D006801:Humans; D016104:Oligohydramnios / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control*; D011446:Prospective Studies; D014867:Water / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D014867:Water