title: The application of bioflocs technology to protect brine shrimp (Artemia franciscana) from pathogenic Vibrio harveyi.
abstract: OBJECTIVE
  To study the potential biocontrol activity of bioflocs technology.
  
  
  RESULTS
  Glycerol-grown bioflocs were investigated for their antimicrobial and antipathogenic properties against the opportunistic pathogen Vibrio harveyi. The bioflocs did not produce growth-inhibitory substances. However, bioflocs and biofloc supernatants decreased quorum sensing-regulated bioluminescence of V. harveyi. This suggested that the bioflocs had biocontrol activity against this pathogen because quorum sensing regulates virulence of vibrios towards different hosts. Interestingly, the addition of live bioflocs significantly increased the survival of gnotobiotic brine shrimp (Artemia franciscana) larvae challenged to V. harveyi.
  
  
  CONCLUSIONS
  Bioflocs grown on glycerol as carbon source inhibit quorum sensing-regulated bioluminescence in V. harveyi and protect brine shrimp larvae from vibriosis.
  
  
  CONCLUSIONS
  The results presented in this study indicate that in addition to water quality control and in situ feed production, bioflocs technology could help in controlling bacterial infections within the aquaculture pond.
authors.affiliation: Laboratory of Microbial Ecology and Technology (LabMET), Ghent University, Gent, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Crab
authors.forename: A
authors.initials: A
authors.lastname: Lambert
authors.forename: T
authors.initials: T
authors.lastname: Defoirdt
authors.forename: P
authors.initials: P
authors.lastname: Bossier
authors.forename: W
authors.initials: W
authors.lastname: Verstraete
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D017756:Aquaculture; D001156:Artemia / Q000187:drug effects / Q000382:microbiology*; D005990:Glycerol / Q000494:pharmacology; D007814:Larva / Q000382:microbiology; D053038:Quorum Sensing / Q000187:drug effects; D014733:Vibrio / Q000502:physiology
chemical_list: D000890:Anti-Infective Agents; D005990:Glycerol