Applications for profiling the schistosome transcriptome.
Some of the most fruitful applications of gene expression studies of schistosome parasites have occurred in the last decade. Recent transcriptomics approaches to schistosome research from an expanding biological perspective will be reviewed, ranging from the whole organism tissue or cellular levels. The latest studies of transcription in relation to schistosome-host interactions are examined, including the impact of the environment or therapies on the parasite and the reciprocal impact the parasite has on the host. Finally, the relevance of transcriptomics for exploring and contrasting different parasite populations or species is discussed.
Gobert
Geoffrey N
GN
Queensland Institute of Medical Research, Division of Infectious Diseases, Molecular Parasitology Laboratory, 300 Herston Rd, Herston, Brisbane, Queensland 4006, Australia. geoffG@qimr.edu.au
D000818:Animals; D001769:Blood / Q000469:parasitology; D005260:Female; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D015801:Helminth Proteins / Q000235:genetics / Q000378:metabolism*; D006790:Host-Parasite Interactions; D006801:Humans; D008018:Life Cycle Stages; D008297:Male; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis; D012547:Schistosoma / Q000166:cytology* / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D012548:Schistosoma haematobium / Q000166:cytology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D012550:Schistosoma mansoni / Q000166:cytology / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D012552:Schistosomiasis / Q000469:parasitology; D012908:Snails / Q000469:parasitology; D013045:Species Specificity
D015801:Helminth Proteins