title: Determination of indoxacarb enantiomer residues in vegetables, fruits, and soil by high-performance liquid chromatography.
abstract: An effective chiral analytical method was developed for the resolution and determination of indoxacarb enantiomers in cucumber, tomato, apple, pear, and soil samples. Indoxacarb enantiomers were separated on a Chiralpak AS-H column with n-hexane-ethanol (95 + 5, v/v) as the mobile phase. Validation involved complete resolution of each enantiomer, plus determination of linearity, precision, LOD, and LOQ. The estimated LOD was 0.025-0.035 mg/kg, and the LOQ was 0.05 mg/kg for each indoxacarb enantiomer in different matrixes. The average recoveries of the pesticide from all matrixes ranged from 87.0 to 116.9% for fortification levels of 0.05, 0.1, and 5 mg/kg. The precision values associated with the analytical method, expressed as RSD(r) values, were < 10.1% for the pesticide in all matrixes. This method can be used to evaluate environmental residues and the safety of agricultural products.
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, Beijing 100193, China.
authors.forename: Li
authors.initials: L
authors.lastname: Cheng
authors.forename: Feng-Shou
authors.initials: FS
authors.lastname: Dong
authors.forename: Xingang
authors.initials: X
authors.lastname: Liu
authors.forename: Wuwing
authors.initials: W
authors.lastname: Chen
authors.forename: Yuanbo
authors.initials: Y
authors.lastname: Li
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Zheng
authors.forename: Dongmei
authors.initials: D
authors.lastname: Qin
authors.forename: Yong
authors.initials: Y
authors.lastname: Gong
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005638:Fruit / Q000737:chemistry*; D057230:Limit of Detection; D010078:Oxazines / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D015203:Reproducibility of Results; D012987:Soil / Q000032:analysis*; D052616:Solid Phase Extraction; D013237:Stereoisomerism; D014675:Vegetables / Q000737:chemistry*
chemical_list: D010078:Oxazines; D010573:Pesticide Residues; D012987:Soil; C401104:indoxacarb