Necrotizing sialometaplasia in a patient who is HIV positive: a case report.
Necrotizing sialometaplasia (NS) is a self-limiting, benign, inflammatory disease of the minor salivary glands of the hard palate. The main significance of the NS lesion lies in the fact that it may be mistaken for mucoepidermoid or squamous cell carcinoma. A case report is presented of a patient with NS who was HIV positive; the lesion was located in the minor salivary glands of the hard palate. Clinically, the lesion presented as a deep ulcer with slightly elevated irregular borders and a necrotic base in the hard palate. Histologically, the tissue was characterized by squamous metaplasia of ducts and acini, lobular coagulation necrosis, and pseudoepitheliomatous hyperplasia of the overlying epithelium. The lesion disappeared completely after 2 weeks.
Silva
Alessandra Dutra
AD
Institute and Research Center São Leopoldo Mandic, Campinas, São Paulo, Brazil. alessandradutrasilva@hotmail.com
Silva
Carolina Amália Barcellos
CA
Furuse
Cristiane
C
Nunes e Souza
Rodrigo Calado
RC
da Costa
Mauro Henrique Melo
MH
de Araújo
Vera Cavalcanti
VC
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis; D019226:Oral Ulcer / Q000175:diagnosis; D021362:Palate, Hard / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*; D012797:Sialometaplasia, Necrotizing / Q000175:diagnosis*