title: Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud.
abstract: CONCLUSIONS
  We present the first parallel implementation of the T-Coffee consistency-based multiple aligner. We benchmark it on the Amazon Elastic Cloud (EC2) and show that the parallelization procedure is reasonably effective. We also conclude that for a web server with moderate usage (10K hits/month) the cloud provides a cost-effective alternative to in-house deployment.
  
  
  BACKGROUND
  T-Coffee is a freeware open source package available from http://www.tcoffee.org/homepage.html
authors.affiliation: Centre For Genomic Regulation (Pompeu Fabra University), Carrer del Doctor Aiguader 88, Barcelona, Spain.
authors.forename: Paolo
authors.initials: P
authors.lastname: Di Tommaso
authors.forename: Miquel
authors.initials: M
authors.lastname: Orobitg
authors.forename: Fernando
authors.initials: F
authors.lastname: Guirado
authors.forename: Fernado
authors.initials: F
authors.lastname: Cores
authors.forename: Toni
authors.initials: T
authors.lastname: Espinosa
authors.forename: Cedric
authors.initials: C
authors.lastname: Notredame
mesh_terms: D000465:Algorithms; D020407:Internet; D016415:Sequence Alignment / Q000379:methods*; D012984:Software