Bilateral optic neuritis due to isoniazid (INH).
Optic nerve involvement is a rare side effect of isoniazid (INH) and has not been described in children. We describe this adverse reaction in a 10-year-old boy, who was treated for tuberculous meningitis. The patient showed almost complete resolution following withdrawal of INH and administration of pyridoxine and steroids.
Kulkarni
H S
HS
Department of Ophthalmology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India.
Keskar
V S
VS
Bavdekar
S B
SB
Gabhale
Y
Y
D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects* / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D009902:Optic Neuritis / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D014390:Tuberculosis, Meningeal / Q000188:drug therapy
D000995:Antitubercular Agents; D007538:Isoniazid