title: Home-based HIV voluntary counselling and testing (VCT) for improving uptake of HIV testing.
abstract: BACKGROUND
  The low uptake of HIV voluntary counselling and testing (VCT) has hindered global attempts to prevent new HIV infections and has limited scale-up of HIV care and treatment. Globally, only 10% of HIV-infected individuals are aware of their HIV status. One approach to increase uptake is home-based HIV VCT, which may be effective in increasing the number of patients on treatment and preventing new infections.
  
  
  OBJECTIVE
  To establish the effect of home-based HIV VCT on uptake of HIV testing
  
  
  METHODS
  We searched MEDLINE (February 2007), EMBASE (February 2007), CENTRAL (February 2007), AIDSearch (February 2007), LILACS, CINAHL and Sociofile. We also contacted relevant researchers. The original review search strategy was updated in 2008.
  
  
  METHODS
  Randomised controlled trials comparing home-based HIV VCT with other testing models
  
  
  METHODS
  Two review authors independently selected studies, assessed methodological quality, and extracted data. We planned to conduct statistical analysis using the Review Manager software and calculate summary statistics (relative risks (RRs) with 95% confidence intervals (CI)) for primary outcomes.
  
  
  RESULTS
  Only one study from developing countries met the inclusion criteria and was included in the review. The study, a cluster randomised trial (10 clusters, n=849) compared VCT uptake between an optional location (including home-based) and a local clinic location in a population-based HIV survey. The study showed a higher uptake of VCT among participants in the optional-location group. Uptake was significantly greater in the optional-location group in those who were pre-test counselled only (RR=4.6; 95% CI 3.58 to 5.91); pretest counselled and tested (RR=4.6; 95% CI 3.51 to 5.92); and post-test counselled and received the test result (RR=4.8; 95% CI 3.62 to 6.21). This study, however, had significant methodological problems limiting further analysis and interpretation.
  
  
  CONCLUSIONS
  Although home-based HIV VCT has the potential to enhance VCT uptake in developing countries, insufficient data exist to recommend large-scale implementation of home-based HIV testing. Further studies are needed to determine if home-based VCT is better than facility-based VCT in improving VCT uptake.
authors.affiliation: Department of Global Health, University of Washington, 901 Boren Avenue, Suite 1100, Seattle, Washington, USA, 98104-3508.
authors.forename: Moses
authors.initials: M
authors.lastname: Bateganya
authors.forename: Omar A
authors.initials: OA
authors.lastname: Abdulwadud
authors.forename: Susan M
authors.initials: SM
authors.lastname: Kiene
mesh_terms: D016000:Cluster Analysis; D003256:Community Participation / Q000706:statistics & numerical data; D003376:Counseling / Q000706:statistics & numerical data / Q000600:supply & distribution*; D003906:Developing Countries / Q000706:statistics & numerical data*; D003954:Diagnostic Services / Q000706:statistics & numerical data / Q000600:supply & distribution*; D015658:HIV Infections / Q000175:diagnosis*; D006699:Home Care Services / Q000706:statistics & numerical data / Q000600:supply & distribution*; D006801:Humans; D007258:Informed Consent; D015024:Zambia