Alterations in coagulation parameters in dairy cows affected with acute mastitis caused by E. coli and S. aureus pathogens.
This study was conducted to evaluate alterations in coagulation parameters in dairy cows affected with acute Escherichia coli (E. coli) mastitis and to compare those values to cows affected with Staphylococcus aureus (S. aureus ) mastitis. Twenty-four, adult Holstein-Friesian dairy cows affected with acute E. coli mastitis and 17 cows affected with S. aureus mastitis were studied. Cows affected with E. coli mastitis had significantly prolonged activated partial thromboplastin time (APTT) (P < 0.01), prothrombin time (PT) (P < 0.05) and decreased (P < 0.05) platelets numbers. Cows with S. aureus mastitis had only significantly prolonged APTT (P < 0.05) and decreased (P < 0.05) platelet counts. In the hematology evaluation, cows affected with E. coli and those affected with S. aureus mastitis had elevated hematocrit values but only significantly (P < 0.05) so in mastitic cows caused by E. coli. Both groups of mastitic cows had significantly (P < 0.05) lower leukocyte counts. Only cows with E. coli mastitis had significantly (P < 0.05) lower neutrophil count. In the plasma biochemical evaluation, creatinine concentrations were significantly (P < 0.05) elevated in both groups of cows. Blood urea nitrogen (BUN) concentration was only significantly elevated in cows affected with E. coli mastitis. Results of this study indicated that dairy cows affected with acute E. coli mastitis are more likely to develop clinical manifestations of disseminated intravascular coagulation than cows affected with S. aureus mastitis.
Ismail
Zuhair A Bani
ZA
Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan. zishmail@smu.ky
Dickinson
Charles
C
D000818:Animals; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000209:etiology / Q000662:veterinary; D002417:Cattle; D003612:Dairying; D004927:Escherichia coli Infections / Q000097:blood / Q000150:complications / Q000662:veterinary*; D005260:Female; D008414:Mastitis, Bovine / Q000097:blood* / Q000150:complications / Q000382:microbiology; D010314:Partial Thromboplastin Time / Q000662:veterinary*; D010976:Platelet Count / Q000662:veterinary*; D011517:Prothrombin Time / Q000662:veterinary*; D013203:Staphylococcal Infections / Q000097:blood / Q000150:complications / Q000662:veterinary*; D013211:Staphylococcus aureus