[Rapid progression of hepatocellular carcinoma after surgery: apropos of a case and review of the literature].
We report the case of a young man with chronic hepatitis B infection of probable perinatal acquisition who was diagnosed with hepatocellular carcinoma at a very early stage (BCLC 0) with a highly favorable prognosis. However, the tumor progressed rapidly and the patient died within months. Currently, there are few data that could help to identify cases likely to show rapid progression and which could prompt initiation of aggressive therapies that might prevent or control such progression.
Vergara Gómez
Mercedes
M
Unitat de Hepatologia, Servicio de Digestivo, Universitat Autònoma de Barcelona, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, España.
Miquel Planas
Mireia
M
Gil Prades
Montserrat
M
Dalmau Obrador
Blai
B
Casas Rodrigo
Meritxell
M
Sanchez Delgado
Jordi
J
Bella
Maria Rosa
MR
Puig Domingo
Jordi
J
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D018450:Disease Progression; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006498:Hepatectomy / Q000379:methods; D019694:Hepatitis B, Chronic / Q000150:complications / Q000151:congenital / Q000821:virology; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D019259:Lamivudine / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D014463:Ultrasonography; D019562:Viral Load; D000509:alpha-Fetoproteins / Q000032:analysis
D000998:Antiviral Agents; D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; D019259:Lamivudine; D004317:Doxorubicin; D007372:Interferons