title: [Preclinical pharmacological profiles and clinical outcome of the novel melatonin-receptor agonist ramelteon (Rozerem 8 mg).].
authors.affiliation: Hirai_Keisuke@takeda.co.jp
authors.forename: Keisuke
authors.initials: K
authors.lastname: Hirai
authors.forename: Koki
authors.initials: K
authors.lastname: Kato
authors.forename: Hisao
authors.initials: H
authors.lastname: Nishikawa
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Yukuhiro
authors.forename: Keiji
authors.initials: K
authors.lastname: Nishiyama
authors.forename: Masaomi
authors.initials: M
authors.lastname: Miyamoto
mesh_terms: D000818:Animals; D002908:Chronic Disease; D000242:Cyclic AMP / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007192:Indenes / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D016032:Randomized Controlled Trials as Topic; D044094:Receptors, Melatonin / Q000819:agonists*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*; D012894:Sleep Stages / Q000187:drug effects; D019966:Substance-Related Disorders; D013493:Suprachiasmatic Nucleus / Q000187:drug effects / Q000502:physiology
chemical_list: D007192:Indenes; D044094:Receptors, Melatonin; C495910:ramelteon; D000242:Cyclic AMP