Bonghan system as mesenchymal stem cell niches and pathways of macrophages in adipose tissues.
A new technique for visualizing Bonghan ducts (BHDs) and Bonghan corpuscles (BHCs) was developed by using a vivi-staining dye, Trypan blue. The dye stains BHDs and BHCs preferentially to adipocytes so that tracking a BHD and a BHC, even inside adipose tissues, is possible. Concerning the functions of the BHD and the BHC in adipose tissues, we propose conjectures: the Bonghan system may be niches for mesenchymal stem cells, which can differentiate into adipocytes, and pathways for macrophages involved in adipogenesis.
Lee
Byung-Cheon
BC
Biomedical Physics Laboratory, Department of Physics and Astronomy, Seoul National University, Seoul, Korea.
Bae
Kyung-Hee
KH
Jhon
Gil-Ja
GJ
Soh
Kwang-Sup
KS
D000273:Adipose Tissue / Q000033:anatomy & histology / Q000737:chemistry* / Q000166:cytology; D002454:Cell Differentiation; D003503:Cyclobutanes; D008264:Macrophages / Q000737:chemistry* / Q000166:cytology; D059630:Mesenchymal Stem Cells / Q000737:chemistry* / Q000166:cytology; D013194:Staining and Labeling; D055153:Stem Cell Niche / Q000033:anatomy & histology / Q000737:chemistry* / Q000166:cytology; D014343:Trypan Blue / Q000032:analysis*
D003503:Cyclobutanes; D014343:Trypan Blue; C058254:sibutramine