title: Off-pump coronary artery bypass grafting in a patient with Bernard-Soulier syndrome.
abstract: We report a case of a patient with Bernard-Soulier syndrome who underwent off-pump coronary artery bypass grafting. Bernard-Soulier syndrome is a rare bleeding disorder caused by an abnormality or absence of a platelet membrane receptor (GPIb-IX-V) resulting in prolonged bleeding time, macrothrombocytes, and thrombocytopenia. We describe the strategy for a patient with Bernard-Soulier syndrome undergoing successful coronary artery bypass grafting.
authors.affiliation: Department of Cardiothoracic Surgery, Manchester Heart Centre, Central Manchester University Hospitals, Manchester, UK.
authors.forename: Rana Haris
authors.initials: RH
authors.lastname: Bilal
authors.forename: Ijas
authors.initials: I
authors.lastname: Moideen
authors.forename: Louise
authors.initials: L
authors.lastname: Pyke
authors.forename: Zeid
authors.initials: Z
authors.lastname: Makahleh
authors.forename: Pedro
authors.initials: P
authors.lastname: Fernandez-Jimenez
authors.forename: Ragheb
authors.initials: R
authors.lastname: Hasan
mesh_terms: D001606:Bernard-Soulier Syndrome / Q000150:complications / Q000628:therapy*; D047549:Coronary Artery Bypass, Off-Pump; D003324:Coronary Artery Disease / Q000150:complications / Q000601:surgery*; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D017713:Platelet Transfusion