title: Ischemia-modified albumin levels in patients with end-stage renal disease patients on hemodialysis: does albumin analysis method affect albumin-adjusted ischemia-modified albumin levels?
abstract: Ischemia-Modified albumin (IMA) has been used as an early marker in the evaluation of the patients with acute coronary syndrome. We aimed to evaluate IMA in end-stage renal disease (ESRD) patients on hemodialysis and the effect of albumin methods on albumin-adjusted IMA levels. A total of 30 ESRD patients were included in this study. Serum IMA and albumin levels were measured before and after a hemodialysis session. Albumin concentrations were determined with bromocresol green and bromocresol purple methods. Postdialysis IMA and albumin-adjusted IMA levels with two different albumin methods were significantly increased compared with the predialysis levels (P<0.05). However, we did not find any difference in albumin-adjusted IMA levels in either at the beginning or at the end of the dialysis session. IMA levels increase after hemodialysis, whereas albumin method has no effect on albumin-adjusted IMA levels.
authors.affiliation: Department of Biochemistry, Meram Medical Faculty, Selcuk University, Konya, Turkey. ayselkiyici@gmail.com
authors.forename: Aysel
authors.initials: A
authors.lastname: Kiyici
authors.forename: Idris
authors.initials: I
authors.lastname: Mehmetoğlu
authors.forename: Hatice
authors.initials: H
authors.lastname: Karaoğlan
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Atalay
authors.forename: Yalçin
authors.initials: Y
authors.lastname: Solak
authors.forename: Süleyman
authors.initials: S
authors.lastname: Türk
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001961:Bromcresol Green; D001962:Bromcresol Purple; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood*; D006435:Renal Dialysis; D012709:Serum Albumin / Q000032:analysis*
chemical_list: D012709:Serum Albumin; D001962:Bromcresol Purple; D001961:Bromcresol Green