title: Intracerebral haematomas after deep brain stimulation surgery in a patient with Tourette syndrome and low factor XIIIA activity.
abstract: A 24-year-old male patient with refractory Tourette syndrome was treated with deep brain stimulation (DBS) and developed subsequent bilateral subcortical haematomas. Additional blood tests revealed abnormalities of plasma factor XIIIA and tryptophan levels, which may be associated with Tourette syndrome. Neurosurgeons who perform DBS surgery on patients with Tourette syndrome must be aware of possible disastrous complications resulting from factor XIIIA disorders of blood haemostasis. Routine screening for this condition is not typically performed prior to surgery in these patients.
authors.affiliation: Department of Neuroscience, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. zamzuri@kb.usm.my
authors.forename: Zamzuri
authors.initials: Z
authors.lastname: Idris
authors.forename: Abdul Rahman I
authors.initials: AR
authors.lastname: Ghani
authors.forename: Winn
authors.initials: W
authors.lastname: Mar
authors.forename: Shalini
authors.initials: S
authors.lastname: Bhaskar
authors.forename: Wan N
authors.initials: WN
authors.lastname: Wan Hassan
authors.forename: John
authors.initials: J
authors.lastname: Tharakan
authors.forename: Jafri M
authors.initials: JM
authors.lastname: Abdullah
authors.forename: Julia
authors.initials: J
authors.lastname: Omar
authors.forename: Saruddin
authors.initials: S
authors.lastname: Abass
authors.forename: Suryati
authors.initials: S
authors.lastname: Hussin
authors.forename: Wan Z
authors.initials: WZ
authors.lastname: Abdullah
mesh_terms: D046690:Deep Brain Stimulation / Q000009:adverse effects*; D026122:Factor XIIIa / Q000378:metabolism*; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods; D005879:Tourette Syndrome / Q000601:surgery; D055815:Young Adult
chemical_list: D026122:Factor XIIIa