title: [Rapid progression of hepatocellular carcinoma after surgery: apropos of a case and review of the literature].
abstract: We report the case of a young man with chronic hepatitis B infection of probable perinatal acquisition who was diagnosed with hepatocellular carcinoma at a very early stage (BCLC 0) with a highly favorable prognosis. However, the tumor progressed rapidly and the patient died within months. Currently, there are few data that could help to identify cases likely to show rapid progression and which could prompt initiation of aggressive therapies that might prevent or control such progression.
authors.affiliation: Unitat de Hepatologia, Servicio de Digestivo, Universitat Autònoma de Barcelona, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, España.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Vergara Gómez
authors.forename: Mireia
authors.initials: M
authors.lastname: Miquel Planas
authors.forename: Montserrat
authors.initials: M
authors.lastname: Gil Prades
authors.forename: Blai
authors.initials: B
authors.lastname: Dalmau Obrador
authors.forename: Meritxell
authors.initials: M
authors.lastname: Casas Rodrigo
authors.forename: Jordi
authors.initials: J
authors.lastname: Sanchez Delgado
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Bella
authors.forename: Jordi
authors.initials: J
authors.lastname: Puig Domingo
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D018450:Disease Progression; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006498:Hepatectomy / Q000379:methods; D019694:Hepatitis B, Chronic / Q000150:complications / Q000151:congenital / Q000821:virology; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D019259:Lamivudine / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D014463:Ultrasonography; D019562:Viral Load; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000998:Antiviral Agents; D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; D019259:Lamivudine; D004317:Doxorubicin; D007372:Interferons