title: Assessment of global left ventricular systolic function with multidetector CT and 2D echocardiography: a comparison between reconstructions of 1-mm and 2-mm slice thickness at multidetector CT.
abstract: OBJECTIVE
  To compare multidetector computed tomography (MDCT) and two-dimensional transthoracic echocardiography (2DE) for left ventricular ejection fraction (EF); and to make comparison between reconstructions of 1-mm and 2-mm slice thickness at MDCT in left ventricular analysis by using a semiautomated segmentation algorithm.
  
  
  METHODS
  In 43 patients global left ventricular systolic function was assessed by using both MDCT and 2DE. Functional MDCT data sets were reconstructed in 20 cardiac phases (0-95%) with both 1-mm and 2-mm slice thickness.With semi-automatic left ventricle segmentation, end-diastolic volume (EDV), endsystolic volume (ESV) and EF were calculated seperately for both 1-mm and 2-mm reconstructions.
  
  
  RESULTS
  On MDCT with 1-mm slice thickness, mean EF was 66.8 +/- 5.6 %, mean EDV was 133.7 +/- 38.9 mL, and mean ESV was 45.1 +/- 17.9 mL, these values for 2-mm slice thickness were 66.2 +/- 5.6 %, 133.5 +/- 39.6 mL, and 45.9 +/- 18.3 mL, respectively. On 2DE, mean EF was 66.7 +/- 5.7 %, mean EDV was 98.7 +/- 42.1 mL, and mean ESV was 33.6 +/- 18.7 mL. There was no difference between EF values calculated with 1-mm and 2-mm reconstructions and 2DE (P = 0.83 and P = 0.3705, respectively). However, EDV and ESV values calculated by MDCT were significantly higher than those obtained by 2DE (P < 0.0001).
  
  
  CONCLUSIONS
  There was a good correlation between MDCT and 2DE in the evaluation of left ventricular EF. At MDCT left ventricular ESV was statistically smaller, EF was statistically greater by using 1-mm rather than 2-mm slice thickness. However, these differences are not clinically relevant.
authors.affiliation: Department of Radiology, Ankara Numune Education and Research Hospital, Ankara, Turkey. mvural99@hotmail.com
authors.forename: Murat
authors.initials: M
authors.lastname: Vural
authors.forename: Ozgül
authors.initials: O
authors.lastname: Uçar
authors.forename: Nadir Alper
authors.initials: NA
authors.lastname: Selvi
authors.forename: Lale
authors.initials: L
authors.lastname: Paşaoğlu
authors.forename: Müge Onbaşioğlu
authors.initials: MO
authors.lastname: Gürbüz
authors.forename: Hülya
authors.initials: H
authors.lastname: Ciçekçioğlu
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydoğdu
authors.forename: Suha
authors.initials: S
authors.lastname: Koparal
mesh_terms: D017023:Coronary Angiography / Q000379:methods; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D013318:Stroke Volume / Q000502:physiology*; D013599:Systole / Q000502:physiology*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging