title: Scopolamine for cancer-related nausea and vomiting.
abstract: Nausea and vomiting is a common and troublesome symptom in advanced cancer. There have been different approaches described for the management of nausea and vomiting, specifically empirical and etiological. Scopolamine is listed in textbooks as a useful medication in management of nausea and vomiting in this setting, although there is no published data to support this recommendation. We present three cases that support the use of scopolamine in an etiologically based approach for management of nausea in advanced cancer.
authors.affiliation: Section of Palliative Medicine and Supportive Oncology, The Harry R. Horvitz Center for Palliative Medicine, Cleveland, Ohio, USA. legrans@ccf.org
authors.forename: Susan B
authors.initials: SB
authors.lastname: LeGrand
authors.forename: Declan
authors.initials: D
authors.lastname: Walsh
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001018:Aortic Diseases / Q000150:complications / Q000188:drug therapy; D001932:Brain Neoplasms / Q000150:complications / Q000188:drug therapy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000188:drug therapy; D009325:Nausea / Q000139:chemically induced* / Q000188:drug therapy*; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D009837:Oligodendroglioma / Q000150:complications / Q000188:drug therapy; D012601:Scopolamine / Q000627:therapeutic use*; D019043:Vascular Neoplasms / Q000150:complications / Q000188:drug therapy; D014839:Vomiting / Q000139:chemically induced* / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents; D012601:Scopolamine