title: Sequence variability and sequence evolution: an explanation of molecular polymorphisms and why many molecular structures can be preserved although they are not predominant.
abstract: The existence of many processes that regulate RNA expression poses a challenge to the idea that the cell is the culmination of a highly efficient interplay of individual proteins, each with specific, highly specialized functions. It will be demonstrated here the extent to which the cell may undergo evolutionary processes that also occur in the macrocosmos, specifically with reference to the rules of mutation and preservation. These molecular evolutionary processes could facilitate a better understanding of the development of molecular structures and the functioning of the cell and could give an explanation of the molecular polymorphisms and also explain why many molecular structures can be preserved although they are not predominant.
authors.affiliation: Institute of Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg University, Mainz, Germany. arneth@zentrallabor.klinik.uni-mainz.de
authors.forename: Borros M
authors.initials: BM
authors.lastname: Arneth
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D017124:Conserved Sequence; D019143:Evolution, Molecular; D014644:Genetic Variation; D006801:Humans; D008957:Models, Genetic; D015394:Molecular Structure; D009154:Mutation / Q000235:genetics; D011110:Polymorphism, Genetic; D011506:Proteins / Q000235:genetics
chemical_list: D011506:Proteins