title: Mycoplasma bovis in respiratory disease of feedlot cattle.
abstract: Mycoplasma bovis has recently emerged as an important cause of chronic caseonecrotic bronchopneumonia, arthritis, and tenosynovitis in beef cattle. Mycoplasma bovis can act as a primary pathogen, yet many cases are coinfected with other bacteria or viruses, and evidence suggests that M. bovis colonizes and perpetuates lung lesions that were initiated by other bacteria, such as M. haemolytica. Mycoplasma bovis elicits a robust humoral immune response, but the resulting antibodies are not protective because of the variable surface proteins, and vaccines have not yet been shown to prevent disease. Mycoplasma bovis infections are responsible for a high proportion of the chronic disease occurring in feedlots, and the welfare of such animals is an important aspect of feedlot health management.
authors.affiliation: Department of Pathobiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada. jcaswell@uoguelph.ca
authors.forename: Jeff L
authors.initials: JL
authors.lastname: Caswell
authors.forename: Ken G
authors.initials: KG
authors.lastname: Bateman
authors.forename: Hugh Y
authors.initials: HY
authors.lastname: Cai
authors.forename: Fernanda
authors.initials: F
authors.lastname: Castillo-Alcala
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000827:Animal Welfare; D000818:Animals; D000917:Antibody Formation; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000382:microbiology* / Q000517:prevention & control; D005260:Female; D008297:Male; D009175:Mycoplasma Infections / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D045682:Mycoplasma bovis / Q000276:immunology; D037521:Virulence Factors
chemical_list: D037521:Virulence Factors