title: Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report.
abstract: The follicular variant of the adenomatoid odontogenic tumor (AOT) is thought to originate from the reduced enamel epithelium of the dental follicle. The origin of the extra-follicular variant however, remains less clear. This paper presents a case of an extra-follicular AOT, which we believe originated from the epithelial lining of a unicystic ameloblastoma, and reviews the literature. The available evidence seems to indicate that some extra-follicular AOTs might arise as secondary phenomena within pre-existing odontogenic cysts or cystic tumors.
authors.affiliation: Division of Oral Pathology, School of Oral Health Sciences, University of the Witwatersrand, WITS, Johannesburg 2050, South Africa. vcvibha@yahoo.co.uk
authors.forename: Vibha
authors.initials: V
authors.lastname: Jivan
authors.forename: Mario
authors.initials: M
authors.lastname: Altini
authors.forename: Shabnum
authors.initials: S
authors.lastname: Meer
authors.forename: Farzana
authors.initials: F
authors.lastname: Mahomed
mesh_terms: D018254:Adenomatoid Tumor / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D000564:Ameloblastoma / Q000378:metabolism / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000378:metabolism; D064032:Calbindin 2; D006801:Humans; D007573:Jaw Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary; D009808:Odontogenic Tumors / Q000378:metabolism / Q000473:pathology*; D064030:S100 Calcium Binding Protein G / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D064032:Calbindin 2; D064030:S100 Calcium Binding Protein G