title: Synthesis and bioassay of aminosulfonyl-1,3,4-oxadiazoles and their interconversion to 1,3,4-thiadiazoles.
abstract: A new class of oxadiazoles is prepared by treating aminosulfonylacetic acids with different carboxylic acid hydrazides. Interconversion of oxadiazoles to thiadiazoles is carried out with thiourea. The compounds are screened for antimicrobial and antioxidant activities.
authors.affiliation: Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517 502, India. vkpuram2001@yahoo.com
authors.forename: V
authors.initials: V
authors.lastname: Padmavathi
authors.forename: S Nagi
authors.initials: SN
authors.lastname: Reddy
authors.forename: G Dinneswara
authors.initials: GD
authors.lastname: Reddy
authors.forename: A
authors.initials: A
authors.lastname: Padmaja
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001713:Biphenyl Compounds / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D009569:Nitric Oxide / Q000737:chemistry; D010069:Oxadiazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D013830:Thiadiazoles / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D010069:Oxadiazoles; D010851:Picrates; D013830:Thiadiazoles; C058949:1,3,4-thiadiazole; D009569:Nitric Oxide; C004931:1,1-diphenyl-2-picrylhydrazyl