No volumetric differences in the anterior cingulate of psychopathic individuals.
Functional imaging studies of psychopathy have demonstrated reduced activity in the anterior cingulate, yet it is unclear whether this region is structurally impaired. In this study, we used structural MRI to examine whether volumetric differences exist in the anterior cingulate between psychopathic (n=24) and control (n=24) male participants. We found no group differences in the volume of the anterior cingulate or its dorsal and ventral subregions. Our findings call into question whether the anterior cingulate is impaired in psychopathy, or whether previous findings of reduced activity may result from reduced input from other deficient regions.
Glenn
Andrea L
AL
Department of Psychology, University of Pennsylvania, 3809 Walnut Street, Philadelphia, PA 19104, USA. aglenn@sas.upenn.edu
Yang
Yaling
Y
Raine
Adrian
A
Colletti
Patrick
P
D000328:Adult; D000987:Antisocial Personality Disorder / Q000145:classification / Q000473:pathology*; D001931:Brain Mapping; D007839:Functional Laterality; D006179:Gyrus Cinguli / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012111:Residence Characteristics; D055815:Young Adult