title: Spinal low-grade neoplasm with leptomeningeal dissemination mimicking tuberculous meningitis in a child.
abstract: Spinal seeding of primary malignant intracranial tumors via CSF is common. However, this is rare in low-grade glial tumors. Cranial leptomeningeal metastasis of primary spinal cord low-grade gliomas at diagnosis or relapse is extremely rare. Leptomeningeal metastasis of spinal cord low-grade tumors may mimic tuberculous meningitis in children. A patient with primary spinal cord low-grade neoplasm mimicked tuberculous meningitis is presented. The patient successfully treated with chemoradiotherapy. At the end of 19-month follow-up, diffuse leptomeningeal infiltration and a dural mass compatible with relapse developed. Chemoradiotherapy was started.
authors.affiliation: Department of Pediatric Oncology, Institute of Oncology, Hacettepe University, Ankara, Turkey. hdemir@hacettepe.edu.tr
authors.forename: Hacı Ahmet
authors.initials: HA
authors.lastname: Demir
authors.forename: Ali
authors.initials: A
authors.lastname: Varan
authors.forename: Canan
authors.initials: C
authors.lastname: Akyüz
authors.forename: Figen
authors.initials: F
authors.lastname: Söylemezoğlu
authors.forename: Ayşenur
authors.initials: A
authors.lastname: Cila
authors.forename: Münevver
authors.initials: M
authors.lastname: Büyükpamukçu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D005910:Glioma / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D006801:Humans; D055756:Meningeal Carcinomatosis / Q000503:physiopathology / Q000556:secondary* / Q000628:therapy; D011878:Radiotherapy; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D014390:Tuberculosis, Meningeal / Q000473:pathology*