Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group.
A series of new structural benzoylphenylureas (BPUs) containing oxime ether and oxime ester group were designed and synthesized. The larvicidal activities against Oriental armyworm and mosquito of these benzoylphenylureas were evaluated and the result of bioassay displayed specific structure-activity relationship (SAR). Most of the compounds exhibited excellent larvicidal activities against Oriental armyworm and mosquito. Interestingly, some compounds showed different structure-activity relationship towards diamondback moth, beet armyworm, and corn borer although three tested insects all belong to the same insect order.
Sun
Ranfeng
R
State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
Li
Yongqiang
Y
Lü
Maoyun
M
Xiong
Lixia
L
Wang
Qingmin
Q
D000818:Animals; D009033:Culicidae / Q000187:drug effects / Q000254:growth & development; D004952:Esters; D004987:Ethers / Q000737:chemistry*; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry; D007814:Larva / Q000187:drug effects; D008968:Molecular Conformation; D009036:Moths / Q000187:drug effects / Q000254:growth & development; D010091:Oximes / Q000737:chemistry*; D010671:Phenylurea Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D004952:Esters; D004987:Ethers; D007306:Insecticides; D010091:Oximes; D010671:Phenylurea Compounds