title: A modeling and simulation framework to support early clinical drug development decisions in oncology.
authors.affiliation: Strategic Consulting Services, Pharsight-A Certara Company, Mountain View, California, USA. rbruno@pharsight.com
authors.forename: Rene
authors.initials: R
authors.lastname: Bruno
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Lu
authors.forename: Yu-Nien
authors.initials: YN
authors.lastname: Sun
authors.forename: Laurent
authors.initials: L
authors.lastname: Claret
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D003198:Computer Simulation; D015195:Drug Design; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D016019:Survival Analysis
chemical_list: D000970:Antineoplastic Agents