Simultaneous extraction of enrofloxacin and ciprofloxacin from chicken tissue by molecularly imprinted matrix solid-phase dispersion.
An ofloxacin molecularly imprinted polymer was synthesized and used as a dispersant of matrix solid-phase dispersion for the determination of enrofloxacin and ciprofloxacin in chicken tissue. The selected dispersant shows high affinity to enrofloxacin and ciprofloxacin in aqueous environment and could selectively enrich them from chicken tissue matrix. The extract was sufficiently clean for further chromatographic analysis without interferences from template leakage or chicken tissue matrix. Linearity ranged from 0.03 to 200 microg/g with the correlation coefficient r(2)>0.9993. The recoveries of spiked chicken tissues were in the range of 82.7-96.6% for enrofloxacin and 88.7-102% for ciprofloxacin.
Qiao
Fengxia
F
College of Chemical and Environmental Sciences, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding 071002, China. qiaofengxia@126.com
Sun
Hanwen
H
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D002645:Chickens / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin / Q000032:analysis*; D000077422:Enrofloxacin; D024841:Fluoroquinolones / Q000032:analysis*; D054802:Molecular Imprinting; D052616:Solid Phase Extraction / Q000379:methods*
D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077422:Enrofloxacin; D002939:Ciprofloxacin