Sex hormones and bone health in males.
Sex steroids play a key role in maintaining skeletal integrity lifelong, through a complex variety of endocrine, but also paracrine and possibly autocrine actions. The current knowledge that androgens may act as pro-hormones for estrogens has seriously challenged many traditional views, so that, at least for their skeletal actions, these can no longer be considered exclusively "male" or "female" hormones.
Carnevale
Vincenzo
V
Casa Sollievo della Sofferenza Hospital, IRCCS, Viale dei Cappuccini, 71013 San Giovanni Rotondo, Italy. venz.carnevale@libero.it
Romagnoli
Elisabetta
E
Cipriani
Cristiana
C
Del Fiacco
Romano
R
Piemonte
Sara
S
Pepe
Jessica
J
Scillitani
Alfredo
A
Minisola
Salvatore
S
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism / Q000627:therapeutic use; D006262:Health; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy / Q000378:metabolism; D008297:Male; D011956:Receptors, Cell Surface / Q000378:metabolism
D012739:Gonadal Steroid Hormones; D011956:Receptors, Cell Surface