title: Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs.
abstract: Recently in Nature Biotechnology, Rodin et al. (2010), Melkoumian et al. (2010), and Villa-Diaz et al. (2010) described defined, nonxenogenic substrates that support long-term self-renewal of human embryonic stem cells (hESCs). Used in conjunction with defined media, these substrates will facilitate expansion of hESCs for therapeutic applications.
authors.affiliation: Department of Chemical & Biological Engineering, University of Wisconsin-Madison, WI 53706, USA.
authors.forename: Samira M
authors.initials: SM
authors.lastname: Azarin
authors.forename: Sean P
authors.initials: SP
authors.lastname: Palecek