title: Validation of the Pediatric Functional Assessment of Cancer Therapy Questionnaire (Version 2.0) in brain tumor survivors aged 13 years and older.
abstract: We evaluated the reliability and validity of the Pediatric Functional Assessment of Cancer Therapy-Childhood Brain Tumor Survivor Questionnaire (pedsFACT-BrS, Version 2). This was specifically directed to patients aged 13 years and older (adolescents). The pedsFACT-BrS was translated and cross-culturally adapted into Korean, following standard Functional Assessment of Chronic Illness Therapy methodology. The psychometric properties of the pedsFACT-BrS in adolescents were evaluated in 161 brain tumor (BT) patients (mean age=15.53 years). Pretesting was performed in 30 patients, and the results indicated good symptom coverage and overall comprehensibility. In validating the pedsFACT-BrS for adolescents, we found high internal consistency, with Cronbach's α coefficients ranging from 0.76 to 0.91. The pedsFACT-BrS for adolescents also demonstrated good convergent and divergent validities when correlated with the Revised Children's Manifest Anxiety Scale and the Kovacs' Children's Depression Inventory. The pedsFACT-BrS for adolescents showed good clinical validity and effectively differentiated between clinically distinct patient groups according to Karnofsky score, type of treatment, and treatment on/off status. This reliable and valid instrument can now be used to properly evaluate the quality of life of Korean adolescent BT patients.
authors.affiliation: Department of Neurosurgery, Ulsan University College of Medicine, Seoul, Republic of Korea.
authors.forename: Heejung
authors.initials: H
authors.lastname: Yoo
authors.forename: Dong-Seok
authors.initials: DS
authors.lastname: Kim
authors.forename: Hee-Young
authors.initials: HY
authors.lastname: Shin
authors.forename: Jin-Shei
authors.initials: JS
authors.lastname: Lai
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.forename: Hyeon-Jin
authors.initials: HJ
authors.lastname: Park
authors.forename: Young-Shin
authors.initials: YS
authors.lastname: Ra
authors.forename: Woo-Chul
authors.initials: WC
authors.lastname: Kim
authors.forename: Yong-Soon
authors.initials: YS
authors.lastname: Shin
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D012044:Regression Analysis; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*