title: Racial differences in general health, suicidal thoughts, physical and sexual abuse in African-Americans and Caucasians with irritable bowel syndrome.
abstract: OBJECTIVE
  Knowledge of the contribution of race to irritable bowel syndrome (IBS)-associated morbidity helps not only with health care policy decisions but also may provide important clues to the pathophysiologic interactions involved.
  
  
  METHODS
  We conducted a survey at 9 different sites in our metro area. Subjects filled a questionnaire which included Rome II criteria for IBS. Subjects were asked about demographic and clinical characteristics. Subjects with a prior history of chronic inflammatory bowel disease and gastrointestinal cancer were excluded.
  
  
  RESULTS
  Nine hundred and ninety subjects (670 African-Americans and 320 Caucasians) were included in the final analysis. IBS patients had more food allergies and were more likely perceived to have poor health as well as physical limitations. A reduced logistic regression model demonstrated that travel abroad, upper respiratory infections, tonsillectomy, and loss of appetite were independently associated with race in the IBS patients. There were no racial differences in physical or sexual abuse, loss of interest in life, or suicidal thoughts.
  
  
  CONCLUSIONS
  Substantial similarities as well as differences in IBS patients of the two races support the concept that, while there is an important role for a biological component to the pathogenesis of IBS, it by itself may not be an exclusive determinant.
authors.affiliation: Overton Brooks VA Medical Center, Shreveport, LA 71101, USA. anil.minocha@va.gov
authors.forename: Anil
authors.initials: A
authors.lastname: Minocha
authors.forename: Deepthi
authors.initials: D
authors.lastname: Bollineni
authors.forename: William D
authors.initials: WD
authors.lastname: Johnson
authors.forename: William Chad
authors.initials: WC
authors.lastname: Wigington
mesh_terms: D000293:Adolescent; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D004342:Drug Hypersensitivity / Q000150:complications; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000209:etiology* / Q000523:psychology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D011584:Psychology; D012742:Sex Offenses / Q000523:psychology*; D013405:Suicide / Q000523:psychology*; D014195:Travel / Q000706:statistics & numerical data; D044465:White People / Q000706:statistics & numerical data*; D055815:Young Adult