title: Herpes simplex virus reactivation after subtotal hemispherectomy in a pediatric patient.
abstract: We report herpes simplex encephalitis (HSE) in a toddler after a subtotal hemispherectomy for seizures related to HSE 16 months earlier. Herpes simplex virus reactivation in the cerebrospinal fluid shortly after treatment of HSE has been described, but is extremely rare in other situations. HSE reactivation is a potential complication of epilepsy surgery after HSE in children.
authors.affiliation: Pediatric Infectious Diseases, Children's Hospital, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Tracie
authors.initials: T
authors.lastname: Gong
authors.forename: William
authors.initials: W
authors.lastname: Bingaman
authors.forename: Lara
authors.initials: L
authors.lastname: Danziger-Isakov
authors.forename: Ingrid
authors.initials: I
authors.lastname: Tuxhorn
authors.forename: Johanna
authors.initials: J
authors.lastname: Goldfarb
mesh_terms: D002555:Cerebrospinal Fluid / Q000821:virology; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis* / Q000821:virology; D004827:Epilepsy / Q000601:surgery; D038421:Hemispherectomy / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D018139:Simplexvirus / Q000302:isolation & purification*; D014775:Virus Activation