title: Syntheses of novel azasugar-containing mimics of heparan sulfate fragments as potential heparanase inhibitors.
abstract: A series of eight novel, highly modified mono-, di- and trisaccharide derivatives, each containing an iminoalditol moiety, has been synthesized in the quest for potential heparanase inhibitors.
authors.affiliation: Carbohydrate Chemistry, Industrial Research Limited, Lower Hutt, New Zealand.
authors.forename: Kirsty A
authors.initials: KA
authors.lastname: Allen
authors.forename: Rosemary L
authors.initials: RL
authors.lastname: Brown
authors.forename: Gillian
authors.initials: G
authors.lastname: Norris
authors.forename: Peter C
authors.initials: PC
authors.lastname: Tyler
authors.forename: Derek K
authors.initials: DK
authors.lastname: Watt
authors.forename: Olga V
authors.initials: OV
authors.lastname: Zubkova
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D006497:Heparan Sulfate / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D000099175:Heparanase
chemical_list: D001372:Aza Compounds; D004791:Enzyme Inhibitors; D005966:Glucuronidase; D006497:Heparan Sulfate; D000099175:Heparanase