title: All roads lead to the ribosome.
abstract: In this issue of Cancer Cell, She et al. show that in cancer cells a protein called 4E-BP1 is a key integrator of protein synthesis downstream of the ERK and AKT signaling pathways, providing an intriguing rationale for why their simultaneous targeting could enhance therapeutic efficacy.
authors.affiliation: Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.
authors.forename: Steven
authors.initials: S
authors.lastname: Whittaker
authors.forename: Matthew
authors.initials: M
authors.lastname: Martin
authors.forename: Richard
authors.initials: R
authors.lastname: Marais