Analgesic and antipyretic effects of Sansevieria trifasciata leaves.
The ethanol and water extracts of Sansevieria trifasciata leaves showed dose-dependent and significant (P < 0.05) increase in pain threshold in tail-immersion test. Moreover, both the extracts (100 - 200 mg/kg) exhibited a dose-dependent inhibition of writhing and also showed a significant (P < 0.001) inhibition of both phases of the formalin pain test. The ethanol extract (200 mg/kg) significantly (P < 0.01) reversed yeast-induced fever. Preliminary phytochemical screening of the extracts showed the presence of alkaloids, flavonoids, saponins, glycosides, terpenoids, tannins, proteins and carbohydrates.
Anbu
Jeba Sunilson J
JS
School of Pharmacy, Masterskill University College of Health Sciences, 43200 Cheras, Selangor, Malaysia. anbujsunil@yahoo.co.in
Jayaraj
P
P
Varatharajan
R
R
Thomas
John
J
Jisha
James
J
Muthappan
M
M
D000700:Analgesics / Q000494:pharmacology*; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D005334:Fever / Q000188:drug therapy; D005557:Formaldehyde; D008297:Male; D051379:Mice; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D031444:Sansevieria / Q000737:chemistry*
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D010936:Plant Extracts; D005557:Formaldehyde