Successfully resected intrathoracic low-grade fibromyxoid sarcoma.
A low-grade fibromyxoid sarcoma (LGFMS), an Evans tumor, is highly unusual. It is rarely described as a primary neoplasm in the thoracic cavity. We experienced a case of a 20-year-old woman with a right intrathoracic tumor that was surgically treated. Postoperative pathology of the resected specimen revealed the tumor to be LGFMS based on its histological appearance, immunohistological staining, and evidence of fused in sarcoma (FUS) translocation by fluorescence in situ hybridization. Tumor resection was performed with a free surgical margin, and the resultant chest wall defect was repaired using prosthetic mesh. The patient has been well without any recurrence for 18 months since surgery.
Higuchi
Mitsunori
M
Division of Thoracic Surgery, Department of Surgery 1, Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima 960-1295, Japan. higuchi@fmu.ac.jp
Suzuki
Hiroyuki
H
Shio
Yutaka
Y
Hoshi
Sayuri
S
Gotoh
Mitsukazu
M
D001707:Biopsy, Needle; D005260:Female; D005354:Fibrosarcoma / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D034702:RNA-Binding Protein FUS / Q000235:genetics; D013526:Surgical Mesh; D013899:Thoracic Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D013908:Thoracotomy / Q000295:instrumentation; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic; D016896:Treatment Outcome; D020535:Video-Assisted Surgery / Q000295:instrumentation; D055815:Young Adult
D034702:RNA-Binding Protein FUS