title: Mortality and morbidity due to gastric dilatation-volvulus syndrome in pedigree dogs in the UK.
abstract: OBJECTIVE
  To estimate breed-specific risk of death due to, and prevalence of, gastric dilatation-volvulus (GDV) in UK pedigree dogs.
  
  
  METHODS
  Data were available on the reported cause of and age at death and occurrence of and age at diagnosis of disease from the 2004 purebred dog health survey. A total of 15,881 dogs of 165 breeds had died in the previous 10 years; GDV was the cause of death in 65 breeds. There were 36,006 live dogs of 169 breeds of which 48 breeds had experienced > or =1 episodes of GDV. Prevalence ratios were used to estimate breed-specific GDV mortality and morbidity risks.
  
  
  RESULTS
  Gastric dilatation-volvulus was the cause of death for 389 dogs, representing 2.5% (95% CI: 2.2-2.7) of all deaths reported and the median age at death was 7.92 years. There were 253 episodes in 238 live dogs. The median age at first diagnosis was five years. Breeds at greatest risk of GDV mortality were the bloodhound, Grand Bleu de Gascogne, German longhaired pointer and Neapolitan mastiff. Breeds at greatest risk of GDV morbidity were the Grand Bleu de Gascogne, bloodhound, otterhound, Irish setter and Weimaraner.
  
  
  CONCLUSIONS
  These results suggest that 16 breeds, mainly large/giant, are at increased risk of morbidity/mortality due to GDV.
authors.affiliation: Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk.
authors.forename: Katy M
authors.initials: KM
authors.lastname: Evans
authors.forename: Vicki J
authors.initials: VJ
authors.lastname: Adams
mesh_terms: D000367:Age Factors; D000818:Animals; D049628:Body Size / Q000502:physiology*; D004283:Dog Diseases / Q000401:mortality*; D004285:Dogs; D005260:Female; D013271:Gastric Dilatation / Q000401:mortality / Q000662:veterinary*; D008297:Male; D010375:Pedigree; D015995:Prevalence; D012307:Risk Factors; D013277:Stomach Volvulus / Q000401:mortality / Q000662:veterinary*; D006113:United Kingdom / Q000453:epidemiology