Intracerebral haematomas after deep brain stimulation surgery in a patient with Tourette syndrome and low factor XIIIA activity.
A 24-year-old male patient with refractory Tourette syndrome was treated with deep brain stimulation (DBS) and developed subsequent bilateral subcortical haematomas. Additional blood tests revealed abnormalities of plasma factor XIIIA and tryptophan levels, which may be associated with Tourette syndrome. Neurosurgeons who perform DBS surgery on patients with Tourette syndrome must be aware of possible disastrous complications resulting from factor XIIIA disorders of blood haemostasis. Routine screening for this condition is not typically performed prior to surgery in these patients.
Idris
Zamzuri
Z
Department of Neuroscience, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. zamzuri@kb.usm.my
Ghani
Abdul Rahman I
AR
Mar
Winn
W
Bhaskar
Shalini
S
Wan Hassan
Wan N
WN
Tharakan
John
J
Abdullah
Jafri M
JM
Omar
Julia
J
Abass
Saruddin
S
Hussin
Suryati
S
Abdullah
Wan Z
WZ
D046690:Deep Brain Stimulation / Q000009:adverse effects*; D026122:Factor XIIIa / Q000378:metabolism*; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods; D005879:Tourette Syndrome / Q000601:surgery; D055815:Young Adult
D026122:Factor XIIIa