title: Impact of previous mesh hernia repair on the performance of open radical prostatectomy - complications and functional outcome.
abstract: OBJECTIVE
  To determine the impact of previous inguinal mesh hernia repair (IMHR) on the performance of subsequent open radical retropubic prostatectomy (ORRP).
  
  
  METHODS
  A total of 1466 patients underwent ORRP for clinically localized prostate cancer from 2004 to 2008; 51 patients (3.5%) presented with a history of IMHR. Body-mass index (BMI), perioperative blood loss (PBL), operating time (OT), performance of pelvic lymph node dissection (PLD), positive resection-margins (R1), continence and potency between the groups were analysed using Mann-Whitney U and χ(2) tests.
  
  
  RESULTS
  Fifty-one patients with previous IMHR were compared with 1466 patients without previous mesh implantation (nMI) who underwent ORRP. Mean age was 66.8 years and mean BMI 25.7. No statistically difference in the mean OT (68 vs 72 min, P= 0.112), mean PBL (167 vs 156 ml, P= 0.089) or R1 was observed in the pT2-stage tumors (3% vs 9.7%, P= 0.197), or in the pT3-stage tumors (16% vs 21%, P= 0.386). After 3 months 85% showed full continence in the nMI group vs 83.9% MI group (P= 0.864) and after 12 months 94.5% of the nMI patients vs 97.6% with mesh (P= 0.610). The IIEF-5 score after 3 months showed a median of 9.0 in the MI group and 4.5 in the nMI group (P= 0.116) and after 12 months 12.0 in the MI group and 9.0 in the nMI group (P= 0.511). PLD was significantly more feasible in patients that underwent only unilateral IMHR compared with bilateral IMHR (96% vs 40%, P= 0.001) and significantly less feasible if previous IMHR was operated laparoscopically than with an open access (47% vs 88%, P= 0.014).
  
  
  CONCLUSIONS
  No impairment of perioperative variables or functional outcome during ORRP was observed in patients with IMHR. PLD could be performed in a significantly fewer patients who underwent bilateral IMHR or laparoscopic IMHR.
authors.affiliation: Urologische Klinik und Poliklinik der Ludwig-Maximilians-Universität München, Campus Großhadern, München, Deutschland. yasmin.hocaoglu@med.unimuenchen.de
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Hocaoglu
authors.forename: Patrick
authors.initials: P
authors.lastname: Bastian
authors.forename: Alexander
authors.initials: A
authors.lastname: Buchner
authors.forename: Ricarda
authors.initials: R
authors.lastname: Bauer
authors.forename: Markus
authors.initials: M
authors.lastname: Bader
authors.forename: Stefan
authors.initials: S
authors.lastname: Tritschler
authors.forename: Peter
authors.initials: P
authors.lastname: Stanislaus
authors.forename: Christian
authors.initials: C
authors.lastname: Stief
authors.forename: Alexander
authors.initials: A
authors.lastname: Karl
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D005240:Feasibility Studies; D006552:Hernia, Inguinal / Q000150:complications / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D013526:Surgical Mesh; D016896:Treatment Outcome