title: [Mouthwash solutions with microencapsuled natural extracts: Efficiency for dental plaque and gingivitis].
abstract: Mouthwash solutions are mainly used for their antiseptic properties. They currently include synthetic agents (chlorhexidine, triclosan, etc.) or essential oils (especially Listerine). Many natural extracts may also be used. These associate both antiseptic effects and direct action on host response, due to their antioxidant, immunoregulatory, analgesic, buffering, or healing properties. The best known are avocado oil, manuka oil, propolis oil, grapefruit seed extract, pycnogenol, aloe vera, Q10 coenzyme, green tea, and megamin. The development of new technologies, such as microencapsulation (GingiNat concept), may allow an in situ slow release of active ingredients during several hours, and open new perspectives for mouthwash solutions.
authors.affiliation: The LoB5 Foundation for Research, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Vervelle
authors.forename: J
authors.initials: J
authors.lastname: Mouhyi
authors.forename: M
authors.initials: M
authors.lastname: Del Corso
authors.forename: M-P
authors.initials: MP
authors.lastname: Hippolyte
authors.forename: G
authors.initials: G
authors.lastname: Sammartino
authors.forename: D M
authors.initials: DM
authors.lastname: Dohan Ehrenfest
mesh_terms: D000504:Aloe; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D028241:Camellia sinensis; D002710:Chlorhexidine / Q000627:therapeutic use; D032083:Citrus paradisi; D003773:Dental Plaque / Q000517:prevention & control*; D004339:Drug Compounding; D005419:Flavonoids; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D031649:Leptospermum; D009067:Mouthwashes / Q000008:administration & dosage / Q000627:therapeutic use*; D009822:Oils, Volatile / Q000627:therapeutic use; D027421:Persea; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D010938:Plant Oils / Q000627:therapeutic use; D011429:Propolis / Q000627:therapeutic use; D013678:Technology, Pharmaceutical; D014260:Triclosan / Q000627:therapeutic use; D014451:Ubiquinone / Q000031:analogs & derivatives / Q000627:therapeutic use; D017641:Zeolites / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D000975:Antioxidants; D005419:Flavonoids; D009067:Mouthwashes; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils; D017641:Zeolites; D014451:Ubiquinone; D014260:Triclosan; C024070:pycnogenols; D011429:Propolis; C024989:coenzyme Q10; D002710:Chlorhexidine