title: The evidence-base for complementary medicine in children: a critical overview of systematic reviews.
abstract: BACKGROUND
  The use of complementary and alternative medicine (CAM) in paediatric populations is common yet, to date, there has been no synthesis of the evidence of its effectiveness in that population. This overview of systematic review evaluates the evidence for or against the effectiveness of CAM for any childhood condition.
  
  
  METHODS
  Medline, AMED and Cochrane were searched from inception until September 2009. Reference lists of retrieved articles were hand-searched. Experts in the field of CAM were contacted. No language restrictions were applied.
  
  
  RESULTS
  17 systematic reviews were included in this overview, covering acupuncture, chiropractic, herbal medicine, homeopathy, hypnotherapy, massage and yoga. Results were unconvincing for most conditions although there is some evidence to suggest that acupuncture may be effective for postoperative nausea and vomiting, and that hypnotherapy may be effective in reducing procedure-related pain. Most of the reviews failed to mention the incidence of adverse effects of CAMs.
  
  
  CONCLUSIONS
  Although there is some encouraging evidence for hypnosis, herbal medicine and acupuncture, there is insufficient evidence to suggest that other CAMs are effective for the treatment of childhood conditions. Many of the systematic reviews included in this overview were of low quality, as were the randomised clinical trials within those reviews, further reducing the weight of that evidence. Future research in CAM for children should conform to the reporting standards outlined in the CONSORT and PRISMA guidelines.
authors.affiliation: Complementary Medicine, Peninsula Medical School, University of Exeter, 25 Victoria Park Road, Exeter EX2 4NT, UK. Katherine.Hunt@pms.ac.uk
authors.forename: Katherine
authors.initials: K
authors.lastname: Hunt
authors.forename: Edzard
authors.initials: E
authors.lastname: Ernst
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D000529:Complementary Therapies / Q000379:methods*; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016032:Randomized Controlled Trials as Topic; D012196:Review Literature as Topic; D016896:Treatment Outcome