Synthesis of azoloquinazolinic systems using ultrasound.
A number of azoloquinazolines has been efficiently synthesized in the cyclocondensation reaction of azoloazines with α,β-unsaturated carbonyl compounds activated with ultrasound. Two main advantages of the suggested procedure are shorter reaction time and higher yields compared to reflux and stirring at room temperatures. In addition, the yields of dehydrogenization products were decreased.
Sidorenko
D Yu
DY
V.N. Karazin Kharkov National University, Organic Chemistry Department, Svobody sq. 4, 61077 Kharkov, Ukraine. dmitriy.yu.sidorenko@univer.kharkov.ua
Orlov
V D
VD
D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014465:Ultrasonics
D006575:Heterocyclic Compounds, 3-Ring; D011799:Quinazolines