title: Clinical and neuropathological findings of acute carbon monoxide toxicity in chihuahuas following smoke inhalation.
abstract: Three adult Chihuahuas were presented for evaluation after smoke inhalation during a house fire. All three dogs received supportive care and supplemental oxygen. After initial improvement, the dogs developed seizures. Despite anticonvulsant therapy and supportive care, the dogs died. The brains of two dogs were examined. Lesions were identified that were compatible with acute carbon monoxide (CO) toxicity. Lesions were confined to the caudate nucleus, the globus pallidus, and the substantia nigra bilaterally, as well as the cerebellum, cerebral cortex, and dorsal thalamus. This case report describes the clinicopathological sequelae in acute CO toxicity.
authors.affiliation: Department of Small Animal Medicine and Surgery, Veterinary Teaching Hospital, College of Veterinary Medicine, The University of Georgia, 501 D.W. Brooks Drive, Athens, Georgia 30602, USA.
authors.forename: Marc
authors.initials: M
authors.lastname: Kent
authors.forename: Kate E
authors.initials: KE
authors.lastname: Creevy
authors.forename: Alexander
authors.initials: A
authors.lastname: Delahunta
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D002249:Carbon Monoxide Poisoning / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D005390:Fires; D008297:Male; D015208:Smoke Inhalation Injury / Q000473:pathology / Q000662:veterinary*