Females, their estrogens, and seizures.
Estrogens are essential for normal brain functions. The effects of estrogens on seizures are contradictory. More studies are necessary to determine under which conditions the estrogens have proconvulsant effects and when the estrogens may have beneficial action in patients with epilepsy.
Velísková
Jana
J
The Saul R Korey Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, New York 10461, USA. jana.veliskova@einstein.yu.edu
De Jesus
Glendis
G
Kaur
Ramanjot
R
Velísek
Libor
L
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004958:Estradiol / Q000494:pharmacology / Q000502:physiology; D004967:Estrogens / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010052:Ovariectomy; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D013226:Status Epilepticus / Q000139:chemically induced / Q000503:physiopathology
D004967:Estrogens; D004958:Estradiol