In water, on water, and by water: mimicking nature's aldolases with organocatalysis and water.
We review recent developments and applications of aldolase-type organocatalytic direct transformations in aqueous media without addition of organic solvent.
Mase
Nobuyuki
N
Department of Molecular Science, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8561, Japan. tnmase@ipc.shizuoka.ac.jp
Barbas
Carlos F
CF
D000446:Aldehyde-Lyases / Q000378:metabolism*; D000447:Aldehydes / Q000138:chemical synthesis / Q000737:chemistry; D055162:Biocatalysis; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D018716:Molecular Mimicry; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000447:Aldehydes; D007659:Ketones; D014867:Water; D000446:Aldehyde-Lyases