title: Swine as the possible source of hepatitis E virus transmission to humans in Thailand.
abstract: This report describes a study that provides evidence of HEV transmission from pigs to humans in Thailand by applying molecular genetics analysis. It was found that viruses recovered from Thai patients are closely related to genotype 3 and swine hepatitis E virus in Thailand. Based on analysis of a 302-base-pair ORF2 fragment, the strains investigated belong to subgroup 3e and are closely related to European strains. Based on the results obtained, swine are suspected to be a source of HEV transmission to humans in Thailand.
authors.affiliation: Department of Pediatrics, Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University and Hospital, Bangkok, Thailand.
authors.forename: Kamol
authors.initials: K
authors.lastname: Suwannakarn
authors.forename: Chitima
authors.initials: C
authors.lastname: Tongmee
authors.forename: Apiradee
authors.initials: A
authors.lastname: Theamboonlers
authors.forename: Piyawat
authors.initials: P
authors.lastname: Komolmit
authors.forename: Yong
authors.initials: Y
authors.lastname: Poovorawan
mesh_terms: D000818:Animals; D016000:Cluster Analysis; D005838:Genotype; D016751:Hepatitis E / Q000635:transmission* / Q000662:veterinary*; D016752:Hepatitis E virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D013552:Swine / Q000821:virology*; D013553:Swine Diseases / Q000635:transmission* / Q000821:virology; D013785:Thailand; D014764:Viral Proteins / Q000235:genetics; D015047:Zoonoses / Q000635:transmission* / Q000821:virology
chemical_list: C400971:ORF2 protein, Hepatitis E virus; D012367:RNA, Viral; D014764:Viral Proteins