title: Enantioselective reduction of ketones and imines catalyzed by (CN-box)Re(V)-oxo complexes.
abstract: The development and application of chiral, non-racemic Re(V)-oxo complexes to the enantioselective reduction of prochiral ketones is described. In addition to the enantioselective reduction of prochiral ketones, we report the application of these complexes to 1) a tandem Meyer-Schuster rearrangement/reduction to access enantioenriched allylic alcohols and 2) the enantioselective reduction of imines.
authors.affiliation: Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.
authors.forename: Kristine A
authors.initials: KA
authors.lastname: Nolin
authors.forename: Richard W
authors.initials: RW
authors.lastname: Ahn
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Joshua J
authors.initials: JJ
authors.lastname: Kennedy-Smith
authors.forename: F Dean
authors.initials: FD
authors.lastname: Toste
mesh_terms: D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D003486:Cyanides; D007097:Imines; D007659:Ketones