Review of HPTLC in drug analysis: 1996-2009.
Analytical methods for drug substances, formulations, and clinical samples developed and validated on HPTLC plates during the period 1996-2009 are reviewed. Procedures, materials, and instrumentation for the different steps in the HPTLC procedure and validation of results; applications to bulk drugs, formulations, stability studies, biological samples (e.g., urine and plasma), and hydrophobicity studies; and prospects for the use of HPTLC for drug analysis in the future are described.
Sherma
Joseph
J
Lafayette College, Department of Chemistry, Easton, PA 18042, USA. shermaj@lafayette.edu
D002855:Chromatography, Thin Layer / Q000379:methods*; D003720:Densitometry; D057927:Hydrophobic and Hydrophilic Interactions; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013237:Stereoisomerism; D013997:Time Factors
D004364:Pharmaceutical Preparations