title: Health economics perspective of the components of the cardiometabolic syndrome.
abstract: The components of the cardiometabolic syndrome (CMS) increase the risk of coronary artery disease (CAD). The authors compared 12-month costs of subjects with different number of components of the CMS. In claims data from a large health benefits company, 383,420 individuals with the first International Classification of Diseases, Ninth Revision codes for hypertension, diabetes, lipid abnormalities, and obesity were identified. Patients were stratified according to presence of CAD and the number of components of the CMS. Twelve-month costs were added after the identification of the risk factor. Mean annual costs increased with the number of components of CMS both in those with and without CAD, even after adjusting for age, sex, and comorbidities (P<.01). Similar trends were seen for medical and pharmacy costs. The adjusted total annual health care cost in those with an isolated component of the CMS was $5564 (95% confidence interval: $5491-$5631) while in those with 4 components was $12,287 (95% confidence interval: $11,987-$12,587). Individuals with accumulating components of the CMS have higher health care costs regardless of age, sex, and other comorbidities.
authors.affiliation: Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA. ltamariz@med.miami.edu
authors.forename: Leonardo
authors.initials: L
authors.lastname: Tamariz
authors.forename: Ana
authors.initials: A
authors.lastname: Palacio
authors.forename: Yadong
authors.initials: Y
authors.lastname: Yang
authors.forename: Donald
authors.initials: D
authors.lastname: Parris
authors.forename: Rami
authors.initials: R
authors.lastname: Ben-Joseph
authors.forename: Hermes
authors.initials: H
authors.lastname: Florez
mesh_terms: D015331:Cohort Studies; D016001:Confidence Intervals; D003324:Coronary Artery Disease / Q000191:economics*; D005260:Female; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006279:Health Maintenance Organizations / Q000191:economics; D006305:Health Status Indicators; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000191:economics*; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011237:Predictive Value of Tests; D011243:Preferred Provider Organizations / Q000191:economics; D012189:Retrospective Studies; D012307:Risk Factors