title: Monocyte and macrophage biology: an overview.
abstract: This review provides an overview of the current understanding of the biology of monocytes and macrophages. It focuses on four rapidly advancing areas that underpin recent conceptual advances, namely: (1) the bone marrow origins of monocytes and macrophages, (2) monocyte heterogeneity, (3) the early inflammatory consequences of tissue injury, and (4) current concepts of macrophage activation and their limitations.
authors.affiliation: Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria. andrew.rees@meduniwien.ac.at
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Rees
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000502:physiology; D006801:Humans; D007674:Kidney Diseases / Q000276:immunology*; D008262:Macrophage Activation; D008264:Macrophages / Q000502:physiology*; D051379:Mice; D009000:Monocytes / Q000502:physiology*