title: Secondary excision for cervical intraepithelial neoplasia: an evaluation of two treatment methods.
abstract: A small proportion of women require repeat treatments for cervical intraepithelial neoplasia (CIN). This study aimed to compare the effectiveness of two cervical excisional techniques offered within a London teaching hospital (large loop excision of the transformation zone (LLETZ) and laser cone biopsy) when carried out as secondary procedures. A significantly larger volume of tissue was excised following laser cone biopsy, however the depth of the specimen did not differ significantly. A trend for a larger percentage of secondary specimens, resulting in complete endo-cervical margins and a larger proportion of women achieving cytology negative for CIN post-treatment was shown within the laser cone biopsy group.
authors.affiliation: Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK. juliebowring@yahoo.co.uk
authors.forename: J
authors.initials: J
authors.lastname: Bowring
authors.forename: I
authors.initials: I
authors.lastname: Tulloch
authors.forename: S V
authors.initials: SV
authors.lastname: Phadnis
authors.forename: M P A
authors.initials: MP
authors.lastname: Young
authors.forename: H
authors.initials: H
authors.lastname: Evans
authors.forename: P
authors.initials: P
authors.lastname: Walker
mesh_terms: D001706:Biopsy / Q000379:methods; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D003127:Colposcopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D012086:Reoperation; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*