Ectopia cordis in a fetus with mosaic trisomy 16.
Ectopia cordis and mosaic trisomy 16 are two rare fetal anomalies, which have not been reported in association. We report a case of an isolated ectopia cordis at 11(+3) weeks. Subsequent embryological examination confirmed thoracic ectopia cordis with normal heart structure and array comparative genomic hybridization of fetal tissue detected trisomy 16 mosaicism.
Arnaoutoglou
Christos
C
Fetal Medicine Unit, 1st Department of Obstetrics & Gynecology, Papageorgiou Hospital, Aristotle University of Thessaloniki, Periferiakos Str., 56429, Thessaloniki, Greece.
Meditskou
Soultana
S
Keivanidou
Anastasia
A
Manthou
Marilena
M
Anesidis
Nikolaos
N
Assimakopoulos
Efstratios
E
Athanasiadis
Apostolos
A
Kumar
Sailesh
S
D000025:Abortion, Eugenic; D000328:Adult; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics; D054083:Ectopia Cordis / Q000000981:diagnostic imaging* / Q000235:genetics; D005260:Female; D006801:Humans; D009030:Mosaicism; D011247:Pregnancy; D014314:Trisomy / Q000175:diagnosis / Q000235:genetics; D016216:Ultrasonography, Prenatal / Q000379:methods*; D055815:Young Adult