title: Immediate and long-term results of coronary angioplasty in patients aged 80 years and older.
abstract: Objectives. To observe the short- and long-term outcomes after percutaneous coronary intervention (PCI) in octogenarians (>80 y.o.) at our institution. Method. All octogenarians who underwent PCI during the study period were retrospectively retrieved from our database and clinically followed. Major adverse cardiac (and cerebral) events (MAC(C)E) was considered as primary outcome. Results. From January 2003 to December 2007, 140 octogenarians (mean age: 85+/-3 y.o., 79% of male) underwent PCI and were clinically followed 14+/-11 months. Procedural success was obtained in 100 percent of patients with single vessel disease, in 96 percent of patients with double vessel disease, and in 75 percent of patients with triple vessel disease. In-hospital, 30 days, and one year MACE rates were 5%, 5%, and 10.7%, respectively. Impaired left ventricular (LV) ejection fraction (hazard ratio (HR) = 0.909, 95% confidence interval (CI) = 0.856 to 0.964, P = .002), diabetes mellitus (HR = 5.792, 95% CI = 1.785 to 18.796, P = .003), and low GFR (HR = 2.943, 95% CI = 1.161, to 7.464, P = .023) were independently associated with an increase risk of MACE at long-term followup. Conclusion. Coronary angiography can be successfully performed in elderly patients with single and double vessel disease. The results in triple vessel disease are encouraging. Low LV function, diabetes, and impaired renal function increase the risk of long-term major adverse cardiac events.
authors.affiliation: Department of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Dingguo
authors.initials: D
authors.lastname: Zhang
authors.forename: Tiebing
authors.initials: T
authors.lastname: Zhu
authors.forename: Liansheng
authors.initials: L
authors.lastname: Wang
authors.forename: Chunjian
authors.initials: C
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Fumin
authors.initials: F
authors.lastname: Zhang
authors.forename: Kejiang
authors.initials: K
authors.lastname: Cao
authors.forename: Wenzhu
authors.initials: W
authors.lastname: Ma
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Yang