Recurrent vascular catheter-related bacteremia caused by Delftia acidovorans with different antimicrobial susceptibility profiles.
An 11-year-old girl with metastatic neuroblastoma developed recurrent bacteremia during sustained neutropenia after autologous peripheral blood transplantation. All febrile episodes of bacteremia were caused by single Delftia acidovorans strain revealed by ERIC-PCR. This strain became resistant to broad-spectrum penicillins and cephalosporins through antibiotic treatments. Removal of the indwelling vascular catheter resulted in resolution of the infection. So far as we know, this is the first report of vascular catheter-related D. acidovorans bacteremia in Japan.
Kawamura
Ichiro
I
Department of Infectious Diseases, Nagoya University Hospital, Nagoya, Aichi, Japan.
Yagi
Tetsuya
T
Hatakeyama
Kazuhito
K
Ohkura
Teruko
T
Ohkusu
Kiyofumi
K
Takahashi
Yoshiyuki
Y
Kojima
Seiji
S
Hasegawa
Yoshinori
Y
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D055499:Catheter-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D002408:Catheters, Indwelling / Q000382:microbiology*; D002648:Child; D004269:DNA, Bacterial / Q000032:analysis; D020605:Delftia acidovorans / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007564:Japan; D008826:Microbial Sensitivity Tests; D009447:Neuroblastoma / Q000382:microbiology*; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology; D036102:Peripheral Blood Stem Cell Transplantation; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D047090:beta-Lactams / Q000494:pharmacology / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S; D047090:beta-Lactams