Intracellular transport: force controls motor switching at filament junctions.
How does cellular traffic switch direction on microtubules, or switch back and forth between microtubule- and actin-based tracks? A pair of recent studies mimics the layout of motors and tracks within the cell to provide intriguing answers to these questions.
Rock
Ronald S
RS
Department of Biochemistry and Molecular Biology, The University of Chicago, GCIS W240, 929 E. 57th St., Chicago, IL 60637, USA. rrock@uchicago.edu
D000199:Actins / Q000378:metabolism*; D001692:Biological Transport; D008870:Microtubules / Q000378:metabolism*
D000199:Actins