Synthesis of functionalized chromenes from Meldrum's acid, 4-hydroxycoumarin, and ketones or aldehydes.
An efficient synthesis of 4-alkyl-4-methyl-3,4-dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-dione or 4-aryl-3,4-dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-diones via reaction 4-hydroxycoumarin with Meldrum's acid and ketones or aldehydes is described.
Sabbaghan
Maryam
M
Faculty of Sciences, Chemistry Department, Shahid Rajaee Teacher Training University, P O Box 16785-163, Tehran, Iran. sabbaghan@srttu.edu
Yavari
Issa
I
Hossaini
Zinatossadat
Z
D015110:4-Hydroxycoumarins / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D001578:Benzopyrans / Q000138:chemical synthesis*; D004146:Dioxanes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure
D015110:4-Hydroxycoumarins; D000447:Aldehydes; D001578:Benzopyrans; D004146:Dioxanes; D007659:Ketones; C076489:Meldrum's acid; C068805:4-hydroxycoumarin