[Normal tissue tolerance to external beam radiation therapy: eye structures].
The radiation dose received by the eye depends on the pathology, tumour location (ocular globe, orbit, neighboring structures) and the radiation technique. The major complication is the complete loss of vision, which is often multifactorial. This article, based on a literature review, describes the radiation effects and the tolerance doses for all eye structures: cornea, lens, retina, optic nerves, orbit and ocular adnexa.
Marchand
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Département d'Oncologie-Radiothérapie, Institut Curie, 26 rue d'Ulm, 75248 Paris cedex 05, France. virginie.marchand@curie.net
Dendale
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R
D003230:Conjunctival Neoplasms / Q000532:radiotherapy; D003315:Cornea / Q000528:radiation effects; D005123:Eye / Q000033:anatomy & histology / Q000528:radiation effects*; D005134:Eye Neoplasms / Q000469:parasitology / Q000532:radiotherapy*; D006801:Humans; D007765:Lacrimal Apparatus / Q000528:radiation effects; D009799:Ocular Physiological Phenomena; D009918:Orbital Neoplasms / Q000532:radiotherapy; D009928:Organ Specificity; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods*; D011879:Radiotherapy Dosage; D012164:Retinal Diseases / Q000532:radiotherapy; D019572:Retinal Neoplasms / Q000532:radiotherapy; D014604:Uveal Neoplasms / Q000532:radiotherapy