title: Allergic fungal sinusitis complicated by fungal brain mass.
abstract: A 36-year-old African American female with a 14-year history of allergic fungal sinusitis (AFS) presented with progressive worsening headache, fevers, proptosis, and a large frontal lobe brain mass. After excisional biopsy, the non-invasive, dematiaceous mold, Bipolaris australiensis, was identified. We review the epidemiology, etiology, pathophysiology, and clinical presentations of fungal sinusitis, as well as the complex management and multifaceted therapeutic modalities of AFS.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA. viola@bcm.edu
authors.forename: George M
authors.initials: GM
authors.lastname: Viola
authors.forename: Richard
authors.initials: R
authors.lastname: Sutton
mesh_terms: D000328:Adult; D001203:Ascomycota / Q000302:isolation & purification / Q000472:pathogenicity; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D005625:Frontal Lobe; D006801:Humans; D009181:Mycoses / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D012008:Recurrence; D012852:Sinusitis / Q000150:complications* / Q000382:microbiology / Q000628:therapy