Size of basal ganglia in suicide attempters, and its association with temperament and serotonin transporter density.
Magnetic resonance imaging was used to compare subcortical volumes of seven suicide attempters with those of six healthy controls. Suicide attempters had 10% smaller right caudate nucleus and 19% bilaterally smaller globus pallidus. In suicide attempters, volumes of the globus pallidus correlated negatively with previously reported measures of solidity (non-impulsive temperament) and serotonin transporter binding potential.
Vang
Fredrik Johannes
FJ
Psychiatry, Department of Clinical Sciences, Lund University, Lund University, SE-221 85 Lund, Sweden. fredrik.vang@med.lu.se
Ryding
Erik
E
Träskman-Bendz
Lil
L
van Westen
Danielle
D
Lindström
Mats Bertil
MB
D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology*; D003042:Cocaine / Q000031:analogs & derivatives; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010555:Personality Inventory; D011485:Protein Binding; D011877:Radionuclide Imaging; D050486:Serotonin Plasma Membrane Transport Proteins / Q000378:metabolism*; D013406:Suicide, Attempted / Q000523:psychology; D013694:Temperament
D050486:Serotonin Plasma Membrane Transport Proteins; C069723:2beta-carbomethoxy-3beta-(4-iodophenyl)tropane; D003042:Cocaine