A case of tongue carcinoma associated with chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation.
Graft-versus-host disease (GVHD) can occur at various sites, including the oral mucosa, where it is associated with a high risk of head and neck cancer. We report the case of a 46-year-old woman with tongue cancer that developed following Hodgkin's lymphoma and chronic GVHD, and we discuss the possible causes of cancer development.
Noguchi
K
K
Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
Nakase
M
M
Inui
M
M
Nakamura
S
S
Okumura
K
K
Tagawa
T
T
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D017024:Chemotherapy, Adjuvant; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000175:diagnosis*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006689:Hodgkin Disease / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D019226:Oral Ulcer / Q000175:diagnosis; D018714:Radiotherapy, Adjuvant; D014062:Tongue Neoplasms / Q000175:diagnosis*