title: Structure determination of selaginellins G and H from Selaginella pulvinata by NMR spectroscopy.
abstract: Selaginellins G (1) and H (2), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata. Their structures were elucidated, and complete assignments of the (1)H and (13)C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC(50) value of 5.3 microg/ml.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Cao
authors.forename: Ji-Jun
authors.initials: JJ
authors.lastname: Chen
authors.forename: Ning-Hua
authors.initials: NH
authors.lastname: Tan
authors.forename: Yong-Ping
authors.initials: YP
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012015:Reference Standards; D032503:Selaginellaceae / Q000737:chemistry*; D014320:Triphenylmethyl Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D014320:Triphenylmethyl Compounds; C555110:selaginellin G