title: Surgical management modifications following systematic additional shaving of cavity margins in breast-conservation treatment.
abstract: BACKGROUND
  Positive wide local excision margins are the most important risk factor of local breast-carcinoma recurrence. Shaving additional margins could lower the need for re-excisions when wide local excision margins are positive and cavity margins are negative.
  
  
  METHODS
  This retrospective study, from January 2007 to December 2008, included 99 women with breast carcinomas who underwent wide local excision with 4 additional, systematically shaved, surgical cavity margins. All therapeutic decisions concerning post-wide local excision treatment were made by consensus during multidisciplinary meetings.
  
  
  RESULTS
  This systematic cavity-shaving strategy avoided 25 re-excisions (25.3%), and 6 patients required new surgery because of carcinoma found in the additional cavity-shaving margins, despite negative wide local excision margins. No preoperative factor predictive of positive cavity margins was identified.
  
  
  CONCLUSIONS
  Systematic shaving of additional cavity margins changed the surgical management after breast-conservation treatment.
authors.affiliation: Obstetrics and Gynecology Department, Lariboisière Hospital, Assitance Publique-Hôpitaux de Paris, Paris, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Héquet
authors.forename: Alexandre
authors.initials: A
authors.lastname: Bricou
authors.forename: Yann
authors.initials: Y
authors.lastname: Delpech
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Barranger
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D012308:Risk Management; D015996:Survival Rate