Immunogenicity associated with the routine use of an influenza A H1N1 vaccine in health care personnel in Guangzhou, China.
We present immunogenicity data on the routine vaccination of 103 health care personnel during the 2009 H1N1 national vaccination campaign. The seroprotection rate (percentage of samples with hemagglutination inhibition titers of > or =1:40) was 83.2% at 30 days postvaccination, lower than those obtained in previously published controlled trials. Low baseline antibody levels and an increase in seroprotection in a negative-control cohort suggest that the virus remains prevalent.
Di
Biao
B
Guangzhou Center for Disease Control and Prevention, Guangzhou, People's Republic of China.
Xu
Xinhong
X
Li
Tiegang
T
Lu
Enjie
E
Wu
Jibin
J
Liu
Yanhui
Y
Chen
Yiyun
Y
Pickerill
Sam
S
Wang
Ming
M
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002681:China; D005260:Female; D006282:Health Personnel; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D007252:Influenza Vaccines