title: Nomenclature of monocytes and dendritic cells in blood.
abstract: Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community.
authors.affiliation: Helmholtz Zentrum München, Gauting, Germany. ziegler-heitbrock@helmholtz-muenchen.de
authors.forename: Loems
authors.initials: L
authors.lastname: Ziegler-Heitbrock
authors.forename: Petronela
authors.initials: P
authors.lastname: Ancuta
authors.forename: Suzanne
authors.initials: S
authors.lastname: Crowe
authors.forename: Marc
authors.initials: M
authors.lastname: Dalod
authors.forename: Veronika
authors.initials: V
authors.lastname: Grau
authors.forename: Derek N
authors.initials: DN
authors.lastname: Hart
authors.forename: Pieter J M
authors.initials: PJ
authors.lastname: Leenen
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Liu
authors.forename: Gordon
authors.initials: G
authors.lastname: MacPherson
authors.forename: Gwendalyn J
authors.initials: GJ
authors.lastname: Randolph
authors.forename: Juergen
authors.initials: J
authors.lastname: Scherberich
authors.forename: Juergen
authors.initials: J
authors.lastname: Schmitz
authors.forename: Ken
authors.initials: K
authors.lastname: Shortman
authors.forename: Silvano
authors.initials: S
authors.lastname: Sozzani
authors.forename: Herbert
authors.initials: H
authors.lastname: Strobl
authors.forename: Marek
authors.initials: M
authors.lastname: Zembala
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Austyn
authors.forename: Manfred B
authors.initials: MB
authors.lastname: Lutz
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000145:classification*; D003713:Dendritic Cells / Q000145:classification*; D006801:Humans; D051379:Mice; D009000:Monocytes / Q000145:classification*; D009626:Terminology as Topic