title: Analysis of the impact of treatment setting on outcomes from methadone treatment.
abstract: How methadone setting, duration of drug career, and dose impact on treatment are assessed. Two hundred fifteen participants were recruited. Analysis revealed significant reductions in drug use at 1 year within all settings, but the pattern varied. Proportions using heroin reduced in all settings, unprescribed benzodiazepines reduced in community, and general practitioner settings and cocaine use reduced in community and Government health board settings. A logistic model controlling for intake methadone dose, setting, previous treatments, and intake heroin use revealed that setting was a significant factor in predicting heroin use at 1 year but was not significant in predicting changes in health. Findings illustrate that drug outcomes improved across all settings, and health did not improve in any setting. For optimum outcomes to be achieved, opiate users must be directed to settings that best match their needs and that the "one-stop-shop for methadone" is not the most effective solution.
authors.affiliation: School of Nursing and Midwifery, Trinity College Dublin, Dublin 2, Ireland. catheirne.comiskey@tcd.ie
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Comiskey
authors.forename: Gemma
authors.initials: G
authors.lastname: Cox
mesh_terms: D001569:Benzodiazepines / Q000008:administration & dosage / Q000009:adverse effects; D019970:Cocaine-Related Disorders / Q000534:rehabilitation; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D007494:Ireland; D016015:Logistic Models; D008137:Longitudinal Studies; D008691:Methadone / Q000008:administration & dosage / Q000627:therapeutic use*; D009294:Narcotics / Q000008:administration & dosage / Q000627:therapeutic use*; D058850:Opiate Substitution Treatment; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D009294:Narcotics; D001569:Benzodiazepines; D008691:Methadone