title: Genetic characteristics of virion protein 2 genes of infectious bursal disease viruses isolated from commercial chickens with clinical disease in South Korea.
abstract: We examined the molecular identification of 13 infectious bursal disease virus (IBDV) strains isolated in Korea from January 2009 to January 2010. Sequence analysis of the variable virion protein 2 gene suggested that 3 of the isolates were very virulent IBDV, 8 of the isolates were classical virulent IBDV, 1 of the isolates was antigenic variant IBDV, and 1 of the isolates was intermediate plus vaccine strain. However, the clinical effects were evident for these strains regardless of classification because each chick flock was raised in various field situations with a different vaccine program and complications by other viruses or bacteria. Therefore, our observations revealed that IBDV strains of 4 genotypes, including vaccine strain, were recently present in South Korea and that the IBDV strains need to be discriminated using genetic characterization of virion protein 2 gene for efficient diagnosis and disease control.
authors.affiliation: Animal Disease Diagnosis Center, National Veterinary Research and Quarantine Service, Manangu, Anyangsi, Gyeonggido 430-824, Korea. kimhr@nvrqs.go.kr
authors.forename: H-R
authors.initials: HR
authors.lastname: Kim
authors.forename: Y-K
authors.initials: YK
authors.lastname: Kwon
authors.forename: Y-C
authors.initials: YC
authors.lastname: Bae
authors.forename: J-K
authors.initials: JK
authors.lastname: Oem
authors.forename: O-S
authors.initials: OS
authors.lastname: Lee
mesh_terms: D000818:Animals; D018175:Birnaviridae Infections / Q000235:genetics / Q000662:veterinary*; D002645:Chickens / Q000821:virology; D014644:Genetic Variation; D005843:Geography; D007243:Infectious bursal disease virus / Q000235:genetics* / Q000302:isolation & purification; D008969:Molecular Sequence Data; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology*; D056910:Republic of Korea; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D014764:Viral Proteins