title: Effect of continuous ingestion of acetic Acid bacteria on memory retention and the synaptic function in aged rats.
abstract: We administered Acetobacter malorum NCI1683 (S24), containing a high concentration of dihydroceramide (7.2 mg/g of dry cell weight), consecutively to aged rats (male Crlj:Wistar rats, 22 months old). The ingestion of Acetobacter malorum for 89 d significantly extended the memory retention in passive avoidance tests, increased the release of acetylcholine with depolarization of brain synaptosomes and decreased the causative agents of neurodegenerative diseases in the cerebral cortices.
authors.affiliation: Central Research Institute, Mizkan Group Corporation, Handa, Aichi. h-fukami@mizkan.co.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fukami
authors.forename: Satoru
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Hideki
authors.initials: H
authors.lastname: Tachimoto
authors.forename: Mikiya
authors.initials: M
authors.lastname: Kishi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kaga
authors.forename: Hatsue
authors.initials: H
authors.lastname: Waki
authors.forename: Machiko
authors.initials: M
authors.lastname: Iwamoto
authors.forename: Yasukazu
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D019342:Acetic Acid / Q000378:metabolism*; D000091:Acetobacter / Q000378:metabolism*; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D004435:Eating; D008297:Male; D008568:Memory / Q000502:physiology*; D051381:Rats; D013569:Synapses / Q000382:microbiology* / Q000502:physiology*; D013997:Time Factors
chemical_list: D015415:Biomarkers; D019342:Acetic Acid