EPO-mediated reduction in Hamp expression in vivo corrects iron deficiency anaemia in TMPRSS6 deficiency.
Peng
Hongfan
H
Truksa
Jaroslav
J
Lee
Pauline
P
D018798:Anemia, Iron-Deficiency / Q000188:drug therapy*; D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000096:biosynthesis*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004921:Erythropoietin / Q000627:therapeutic use*; D005786:Gene Expression Regulation / Q000187:drug effects; D064451:Hepcidins; D008565:Membrane Proteins / Q000172:deficiency*; D051379:Mice; D008817:Mice, Mutant Strains; D011994:Recombinant Proteins; D012697:Serine Endopeptidases / Q000172:deficiency*
D023181:Antimicrobial Cationic Peptides; C579599:Hamp protein, mouse; D064451:Hepcidins; D008565:Membrane Proteins; D011994:Recombinant Proteins; D004921:Erythropoietin; D012697:Serine Endopeptidases; C467801:matriptase 2