A chemoenzymatic route to diversify aminoglycosides enables a microarray-based method to probe acetyltransferase activity.
Tsitovich
Pavel B
PB
Department of Chemistry & The Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, The State University of New York, 657 Natural Sciences Complex, Buffalo, NY 14260, USA.
Pushechnikov
Alexei
A
French
Jonathan M
JM
Disney
Matthew D
MD
D000105:Acetyl Coenzyme A / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D000123:Acetyltransferases / Q000737:chemistry / Q000378:metabolism*; D000617:Aminoglycosides / Q000138:chemical synthesis / Q000378:metabolism*; D046228:Microarray Analysis
D000617:Aminoglycosides; D000105:Acetyl Coenzyme A; D000123:Acetyltransferases