Reversible pituitary hyperplasia at birth in a macrosomic full-term baby boy.
Pituitary hyperplasia is generally associated with end-organ failure such as primary hypothyroidism, physiological changes such as puberty and pregnancy, or neoplasms secreting releasing factors. We present a full-term infant with an enlarged pituitary height of 8 mm at age 3 days despite a normal endocrinological evaluation. Repeat imaging at 5 months of age revealed a normal-size pituitary gland. To our knowledge, pituitary hyperplasia has not been described in a neonate with normal pituitary function.
Osipoff
Jennifer
J
Division of Pediatric Endocrinology, Department of Pediatrics, State University of New York, HSC Level 11, Rm 080, Stony Brook, NY 11794-8111, USA. JOsipoff@notes.cc.sunysb.edu
Peyster
Robert
R
Wilson
Thomas A
TA
D005320:Fetal Macrosomia / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007231:Infant, Newborn; D008297:Male; D010902:Pituitary Gland / Q000473:pathology*; D012075:Remission, Spontaneous