Carcinomatous meningitis secondary to transitional cell bladder cancer.
We report a patient with carcinomatous meningitis secondary to known transitional cell carcinoma of the bladder. The patient presented with multiple focal neurological signs and symptoms. Diagnosis was suggested by magnetic resonance imaging and confirmed by analysis of the cerebrospinal fluid. He received whole brain radiotherapy despite a poor prognosis. To our knowledge, this is only the fifth reported case of neoplastic meningitis due to bladder cancer with confirmatory imaging and cytology and only the fourth reported case that presented with cranial nerve involvement.
Bowen
Casey D
CD
Department of Medicine, Louisiana State University Heatlh Sciences Center, Shreveport, LA 71130, USA.
Von Burton
Gary
G
Bargen
Rebecca C
RC
Madonia
Phillip
P
Zhang
Songlin
S
Toledo
Eduardo Gonzalez
EG
Zweig
Richard
R
Pant
Chaitanya
C
D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D055756:Meningeal Carcinomatosis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000556:secondary*; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D001749:Urinary Bladder Neoplasms / Q000473:pathology*