title: Traditional cardiovascular risk factors and severity of angiographic coronary artery disease in the elderly.
abstract: Over 80% of annual coronary heart disease mortality occurs in the elderly, a rapidly expanding subset of the population. The authors retrospectively examined the relationship between traditional cardiovascular risk factors and atherosclerotic coronary artery disease burden in a cohort of 631 elderly patients undergoing angiography. Age and male sex but not hypertension or dyslipidemia were predictors of presence of obstructive coronary artery disease (Duke score >or=2). Only diabetes mellitus emerged as an independent predictor of obstructive coronary artery disease burden. Smoking was found to be predictive of left main coronary artery disease. In summary, severity of angiographic disease in the elderly as assessed by Duke Myocardial Jeopardy scoring appears to correlate poorly with prevalence of established traditional cardiovascular risk factors.
authors.affiliation: Division of Cardiology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
authors.forename: Vikas
authors.initials: V
authors.lastname: Veeranna
authors.forename: Jyotiranjan
authors.initials: J
authors.lastname: Pradhan
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Niraj
authors.forename: Hesham
authors.initials: H
authors.lastname: Fakhry
authors.forename: Luis
authors.initials: L
authors.lastname: Afonso
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D015331:Cohort Studies; D016001:Confidence Intervals; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D016015:Logistic Models; D008297:Male; D008824:Michigan / Q000453:epidemiology; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index