title: RPPanalyzer: Analysis of reverse-phase protein array data.
abstract: CONCLUSIONS
  RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data. Implemented plotting functions permit a quality control by monitoring data distribution and signal validity. Finally, the data can be visualized in heatmaps, boxplots, time course plots and correlation plots. RPPanalyzer is a flexible tool and tolerates a huge variety of different experimental designs.
  
  
  BACKGROUND
  The RPPAanalyzer is open source and freely available as an R-Package on the CRAN platform http://cran.r-project.org/.
authors.affiliation: Department of Molecular Genome Analysis, German Cancer Research Center Heidelberg, Germany. h.mannsperger@dkfz.de
authors.forename: Heiko A
authors.initials: HA
authors.lastname: Mannsperger
authors.forename: Stephan
authors.initials: S
authors.lastname: Gade
authors.forename: Frauke
authors.initials: F
authors.lastname: Henjes
authors.forename: Tim
authors.initials: T
authors.lastname: Beissbarth
authors.forename: Ulrike
authors.initials: U
authors.lastname: Korf
mesh_terms: D040081:Protein Array Analysis / Q000379:methods*; D040901:Proteomics / Q000379:methods; D012984:Software