In vivo quantitative reconstruction studies of bioluminescence tomography: effects of peak-wavelength shift and model deviation.
Bioluminescence tomography is a novel optical molecular imaging technology. The corresponding system, theory, and algorithmic frames have been set up. In the present study, we concentrated on the analysis of quantitative reconstruction deviation from peak-wavelength shift of luminescent source and the deviation of heterogeneous mouse model. The findings suggest that the reconstruction results are significantly affected by the peak-wavelength shift and deviation of anatomical structure animal models. Furthermore, the model deviations exhibit much more influence than the wavelength shift on the reconstruction results.
Liu
Junting
J
Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi’an 710071, China. liujunting@fingerpass.net.cn
Chen
Duofang
D
Li
Xiangsi
X
Ma
Xiaopeng
X
Chen
Haichao
H
Fan
Weiwei
W
Wang
Fu
F
Qu
Xiaochao
X
Liang
Jimin
J
Cao
Feng
F
Tian
Jie
J
D000005:Abdomen / Q000033:anatomy & histology; D000465:Algorithms; D000818:Animals; D020342:Finite Element Analysis; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008163:Luminescent Measurements / Q000379:methods*; D051379:Mice; D008954:Models, Biological; D013696:Temperature; D014054:Tomography / Q000379:methods*; D055114:X-Ray Microtomography