title: [Change in the activity of antioxidant defense enzymes in patients with various forms of ischemic heart disease].
abstract: The aim of the study was to clarify the diagnostic value of changes in the activity of first-line antioxidant defense enzymes for the differential diagnosis of different forms of the coronary heart disease (CHD). Excessive hydrogen peroxide production is the leading adaptive compensatory mechanism in the regulation of vascular tone in patients in the acute phase of myocardial infarction. Subacute CHD is characterized by the activation of antiradical defense of cellular and extracellular enzymes during the formation of superoxide anion radical and serves as a good prognostic sign. Evaluation of the red blood cell and plasma activity of superoxide dismutase is recommended for the differential diagnosis of different forms of CHD.
authors.forename: Z I
authors.initials: ZI
authors.lastname: Mikashinovich
authors.forename: R A
authors.initials: RA
authors.lastname: Gridasova
authors.forename: E V
authors.initials: EV
authors.lastname: Olempieva
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D002374:Catalase / Q000097:blood; D003937:Diagnosis, Differential; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000201:enzymology / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000201:enzymology* / Q000503:physiopathology; D011379:Prognosis; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D002374:Catalase; D013482:Superoxide Dismutase