title: An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles.
abstract: The thermally promoted cycloaddition between alkynyliodides and nitrile oxides is reported. The process offers excellent regioselectivity and a broad scope with respect to both the iodoalkynes and chloro-oximes. Further functionalization of the highly decorated iodoisoxazole motifs can be achieved via Suzuki cross-coupling.
authors.affiliation: Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
authors.forename: James A
authors.initials: JA
authors.lastname: Crossley
authors.forename: Duncan L
authors.initials: DL
authors.lastname: Browne