title: Alzheimer's disease and impairment of the Self.
abstract: Impairment of the Self has been described in frontal-temporal dementia but little research has been carried out in patients with Alzheimer's disease (AD).
  
  
  OBJECTIVE
  The aim of this study was to explore changes in the self in patients with AD.
  
  
  METHODS
  Forty-seven patients with mild to moderate AD were examined using a semi-structured scale designed to assess the self-concept along three dimensions, namely, the Material Self, the Social Self and the Spiritual Self.
  
  
  RESULTS
  The majority of patients (43 out of 47) presented impairment of at least one dimension of the Self. When only one dimension was affected, it was always the Social Self. The severity of impairment of the Self was correlated to the impairment of the semantic autobiographical memory and apathy.
  
  
  CONCLUSIONS
  The Self is impaired in AD and the Social Self dimension appears to be more vulnerable in AD than other dimensions.
authors.affiliation: Department of Neurology, CHU of Poitiers, University of Poitiers, France.
authors.forename: M N
authors.initials: MN
authors.lastname: Fargeau
authors.forename: N
authors.initials: N
authors.lastname: Jaafari
authors.forename: S
authors.initials: S
authors.lastname: Ragot
authors.forename: J L
authors.initials: JL
authors.lastname: Houeto
authors.forename: C
authors.initials: C
authors.lastname: Pluchon
authors.forename: R
authors.initials: R
authors.lastname: Gil
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology*; D057565:Apathy; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D008609:Mental Status Schedule; D012648:Self Care / Q000523:psychology*; D012649:Self Concept; D012919:Social Behavior; D029181:Spirituality; D013223:Statistics as Topic; D011795:Surveys and Questionnaires