title: Survival rate of H5N1 highly pathogenic avian influenza viruses at different temperatures.
abstract: The survival rate of Korean H5N1 highly pathogenic avian influenza (HPAI) viruses was investigated at different temperatures under the laboratory conditions. The estimated survival days for a starting viral concentration of 10(6.5) 50% egg infectious dose/0.1 mL were 930, 1,042, and 3,213 d at 4 degrees C; 226, 232, and 293 d at 20 degrees C; and 51, 55, and 58 d at 30 degrees C for A/chicken/Korea/ES/03, A/chicken/Korea/IS/06, and A/chicken/Korea/Gimje/08 (Gimje/08) viruses, respectively. The stability of the Gimje/08 virus was statistically significant compared with the other 2 viruses except for the data between Gimje/08 and A/chicken/Korea/IS/06 virus at 30 degrees C. This result indicated that the survival rate of 3 Korean HPAI viruses is different at various temperatures, which might have partially influenced the large scale of HPAI outbreak in Korea in 2008.
authors.affiliation: Avian Disease Division, National Veterinary Research and Quarantine Service, Anyang, Gyeonggi, 430-757, South Korea.
authors.forename: M R
authors.initials: MR
authors.lastname: Paek
authors.forename: Y J
authors.initials: YJ
authors.lastname: Lee
authors.forename: H
authors.initials: H
authors.lastname: Yoon
authors.forename: H M
authors.initials: HM
authors.lastname: Kang
authors.forename: M C
authors.initials: MC
authors.lastname: Kim
authors.forename: J G
authors.initials: JG
authors.lastname: Choi
authors.forename: O M
authors.initials: OM
authors.lastname: Jeong
authors.forename: J S
authors.initials: JS
authors.lastname: Kwon
authors.forename: O K
authors.initials: OK
authors.lastname: Moon
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Kwon
mesh_terms: D000482:Allantois / Q000821:virology; D000818:Animals; D002645:Chickens / Q000821:virology; D053124:Influenza A Virus, H5N1 Subtype / Q000254:growth & development / Q000472:pathogenicity* / Q000502:physiology*; D005585:Influenza in Birds / Q000453:epidemiology* / Q000821:virology; D012044:Regression Analysis; D013047:Specific Pathogen-Free Organisms; D013696:Temperature