title: Correlation between peripapillary macular fiber layer thickness and visual acuity in patients with open-angle glaucoma.
abstract: OBJECTIVE
  To determine whether the best-corrected visual acuity (BCVA) is significantly correlated with the retinal nerve fiber layer thickness (RNFLT) in the different peripapillary areas in eyes with open-angle glaucoma (OAG).
  
  
  METHODS
  Two hundred twenty-nine eyes of 159 patients with OAG were studied. The overall RNFLT and the RNFLT in the superior (S), temporal (T), inferior (I), and nasal (N) quadrants were measured by Stratus optical coherence tomography (OCT). In addition, the temporal RNFLT was measured for three 30 degrees sectors with the mid-temporal (mT) sector at the three or nine o'clock position. The Spearman coefficient of correlation was calculated to determine whether a significant correlation existed between the RNFLT and the BCVA. Eyes with a BCVA <20/20 were classified as having decreased BCVA.
  
  
  RESULTS
  There were significant correlations between the BCVA and the overall RNFLT, and also between the BCVA and the RNFLT in the T, I, and S quadrants. The coefficient correlation between the BCVA and RNFLT was the highest in the mT sector (r = -0.40, P < 0.0001). Forty-eight eyes (21.1%) were classified as having decreased BCVA. The cut-off value of the mT sector for eyes with decreased VA was 39.0 mum.
  
  
  CONCLUSIONS
  The highest correlation between the BCVA and the RNFLT in the mT sector was most likely due to the location of the maculopapillary bundle in this region of the optic disc. Our findings indicate that when the RNFLT in the mT sector is reduced to 40 mum, glaucoma treatment should be reconsidered.
authors.affiliation: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Miyagi, Japan.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Omodaka
authors.forename: Toru
authors.initials: T
authors.lastname: Nakazawa
authors.forename: Yu
authors.initials: Y
authors.lastname: Yokoyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Doi
authors.forename: Nobuo
authors.initials: N
authors.lastname: Fuse
authors.forename: Kohji
authors.initials: K
authors.lastname: Nishida