Radical cystectomy for bladder cancer in the 70+ population: a nation-wide registry analysis of 845 patients.
OBJECTIVE
To analyze demographics, perioperative mortality and overall survival of radical cystectomy (RC) in patients aged 70+ years in Austria in a nation-wide registry cohort.


METHODS
All patients >69 years who underwent RC in public hospitals (covering >95% of all surgical procedures) in Austria between 1992 and 2004 were analyzed. Data were provided by the Austrian Health Institute (ÖBIG).


RESULTS
A total of 845 patients aged 70-89 years (mean 74) entered the analysis. The annual number of cystectomies in this age group increased from 27 in 1992 to 79 (+292%) in 2004. The mean length of hospital stay declined from 37.1 days (in 1992) to 27.1 days (in 2004). The 60-day mortality of the entire cohort was 1.5% and increased to 5.2% in patients aged 80+ years. Almost 50% of patients had to be rehospitalized within 30 days. The 5-year overall survival declined from 62% in those aged 70-74 years to 61% in those aged 75-79 years to 46% in the oldest age group (80+ years).


CONCLUSIONS
The annual number of cystectomies in patients aged 70+ years increased substantially during the study period. These nation-wide registry data provide insights into the current status of RC in the elderly in Austria and demonstrate that cystectomy in this age cohort can be done with an acceptable perioperative mortality and overall survival.
Madersbacher
Stephan
S
Department of Urology and Andrology, Danube Hospital, Vienna, Austria. stephan.madersbacher @ wienkav.at
Bauer
Wilhelm
W
Willinger
Manfred
M
Wehrberger
Clemens
C
Berger
Ingrid
I
Brössner
Clemens
C
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria; D015331:Cohort Studies; D015653:Cystectomy / Q000379:methods*; D006801:Humans; D008495:Medical Oncology / Q000379:methods; D012042:Registries; D013997:Time Factors; D001743:Urinary Bladder / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000601:surgery*