title: [Arterial hypertension and salt intake].
abstract: More than 25% of adult population worldwide and according to the EHUH study 37% of the adult population of Croatia have hypertension. In the last decades, a dramatic increase has been recorded in the prevalence of hypertension, and it is predicted that this trend will lead to an even higher prevalence in the near future. This could primarily be explained by strong influence of environmental factors. Many epidemiological and interventional studies have proved that high salt intake is one of the most important risk factors. High salt intake increases total peripheral vascular resistance, induces oxidative stress and inflammation, thus accelerating the atherosclerotic process. Independently of the effects on blood pressure, salt intake promotes left ventricular hypertrophy and microalbuminuria and increases the risk of stroke. Interventional studies have shown that salt intake reduction is associated with lower blood pressure and lower cardiovascular morbidity and mortality. Reducing salt intake in daily meals should be the main measure in primary prevention of cardiovascular and renal diseases, and it should be repeatedly emphasized not only to hypertensive patients, but also to the population at large.
authors.affiliation: Klinika za unutrasnje bolesti, Klinicki bolnicki centar Zagreb i Medicinskifakultet Sveujiligta u Zagrebu, Zagreb, Hrvatska. bojan.jelakovic@zg.htnet.hr
authors.forename: Bojan
authors.initials: B
authors.lastname: Jelaković
authors.forename: Ivana
authors.initials: I
authors.lastname: Vuković
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Reiner
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000517:prevention & control; D017673:Sodium Chloride, Dietary / Q000009:adverse effects*
chemical_list: D017673:Sodium Chloride, Dietary