title: Synthesis, characterization and biological studies of some novel thieno[2,3-d]pyrimidines.
abstract: Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolo-thienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized using thermal and microwave (MW) irradiation techniques. Structures of the prepared compounds were elucidated on the basis of IR, NMR, 2D NMR and mass spectral data. The biological activity of some selected synthesized compounds was also examined.
authors.affiliation: Chemistry Department, College of Science, King Faisal University, P.O. Box 400, Hofuf 31982, Saudi Arabia. Kaltisan@yahoo.com
authors.forename: Khulud M
authors.initials: KM
authors.lastname: Al-Taisan
authors.forename: Hassan M A
authors.initials: HM
authors.lastname: Al-Hazimi
authors.forename: Shar S
authors.initials: SS
authors.lastname: Al-Shihry
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D008872:Microwaves; D008956:Models, Chemical; D015394:Molecular Structure; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D011743:Pyrimidines; C476003:thienopyrimidine