title: Endometrial expression of relaxin and relaxin receptor in endometriosis.
abstract: Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosis.
authors.affiliation: Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA. morellsa@umdnj.edu
authors.forename: Sara S
authors.initials: SS
authors.lastname: Morelli
authors.forename: Felice
authors.initials: F
authors.lastname: Petraglia
authors.forename: Gerson
authors.initials: G
authors.lastname: Weiss
authors.forename: Stefano
authors.initials: S
authors.lastname: Luisi
authors.forename: Pasquale
authors.initials: P
authors.lastname: Florio
authors.forename: Andrea
authors.initials: A
authors.lastname: Wojtczuk
authors.forename: Laura T
authors.initials: LT
authors.lastname: Goldsmith
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004715:Endometriosis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D004717:Endometrium / Q000378:metabolism* / Q000473:pathology; D005260:Female; D015870:Gene Expression / Q000502:physiology; D006801:Humans; D008597:Menstrual Cycle / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D010049:Ovarian Diseases / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D043562:Receptors, G-Protein-Coupled / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D018000:Receptors, Peptide / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D012065:Relaxin / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D055815:Young Adult
chemical_list: C417543:RXFP1 protein, human; D043562:Receptors, G-Protein-Coupled; D018000:Receptors, Peptide; D012065:Relaxin