[The identification of the "Beijing family" strain of clinical isolated Mycobacterium tuberculosis in the south region of Xinjiang].
OBJECTIVE
To identify the Beijing family strain of Mycobacterium tuberculosis (M. tuberculosis) in order to find out the distribution of the Beijing family strain in the south region of Xinjiang, and therefore to provide scientific basis for the prevention and treatment of tuberculosis and the study of molecular epidemiology.


METHODS
From Kashi and Hetian Pulmonary Hospitals and Centers for Disease Control and Prevention, the M. tuberculosis strain were collected and isolated from the sputum of inpatients and registered cases infected with M. tuberculosis, from January to June of 2009. The Beijing family strain was identified by RD105 deletion test. The statistical description was performed using frequency and percentage.


RESULTS
A total of 200 clinical isolates of M. tuberculosis was collected. By means of RD105 deletion test, these strains were typed into 2 groups: the Beijing family and the non-Beijing family. Seventy-nine strains belonged to the Beijing family (79/200, 39.5%) and 121 strains to the non-Beijing family (121/200, 60.5%).


CONCLUSIONS
M. tuberculosis of the Beijing family strain is prevalent at a common level in Uygur living in the south region of Xinjiang. It needs to be investigated whether the Beijing family strain of M. tuberculosis is the predominant strain in the whole region.
Wu
Chang-dong
CD
Department of Pathogen Biology and Immunology, College of Medicine, Shihezi University Xinjiang, Shihezi 832002, China.
Wen
Shu
S
Mi
Li-gu
LG
Cao
Hong-yan
HY
Chen
Wei
W
Aierkenjiang
Zipaer
Z
Gong
Tian-mei
TM
Wang
Yuan-zhi
YZ
Li
Yong-xiang
YX
Yuan
Li
L
D015373:Bacterial Typing Techniques; D002681:China / Q000453:epidemiology; D005798:Genes, Bacterial; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D014376:Tuberculosis / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology*