title: [Diagnosis value of electrocardiogram in patients with pulmonary artery hypertension].
abstract: OBJECTIVE
  To analyze the diagnostic value of electrocardiogram (ECG) in patients with pulmonary artery hypertension (PAH) confirmed by right-heart catheterization (RHC).
  
  
  METHODS
  A total of 64 patients with suspected PAH [sPAP > or = 36 mm Hg (1 mm Hg = 0.133 kPa) estimated by echocardiography] were enrolled in this study. All patients were examined by 12-lead ECG within half an hour before RHC.
  
  
  RESULTS
  PAH was excluded in 26 patients and confirmed in 38 patients. ECG analysis showed that S amplitude > 0.21 mV in lead I, QRS axis > 87 degrees , R(V1) + S(V5) > 0.76 mV were good parameters for diagnosing PAH with sensibility and specificity of 89%, 81%; 86%, 92%; 84%, 83%, respectively. QRS axis was positively correlated with mean pulmonary artery pressure (mPAP) (r = 0.75, P < 0.001), R(V1) + S(V5) was positively correlated with pulmonary vascular resistance (PVR) (r = 0.74, P < 0.001), R(V1) + S(V5) and S amplitude in lead I was negatively correlated with cardiac index (CI) (r = -0.62, P < 0.001).
  
  
  CONCLUSIONS
  ECG combined with echocardiography are adequate screening tools to rule out the presence of PAH. QRS axis, R(V1) + S(V5) and S amplitude in lead I were significantly correlated with hemodynamic parameters derived from RHC in PAH patients.
authors.affiliation: Department of Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China.
authors.forename: Qin-hua
authors.initials: QH
authors.lastname: Zhao
authors.forename: Xi-Qi
authors.initials: XQ
authors.lastname: Xu
authors.forename: Zhi-cheng
authors.initials: ZC
authors.lastname: Jing
authors.forename: Ming-li
authors.initials: ML
authors.lastname: Sun
authors.forename: Li-zhi
authors.initials: LZ
authors.lastname: Dai
authors.forename: Wen-hui
authors.initials: WH
authors.lastname: Wu
authors.forename: Xin
authors.initials: X
authors.lastname: Jiang
authors.forename: Jing
authors.initials: J
authors.lastname: He
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
mesh_terms: D000328:Adult; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D014463:Ultrasonography