Complete esophageal obliteration secondary to cytomegalovirus in AIDS patient.
HIV-related benign esophageal strictures have been reported secondary to idiopathic esophageal ulceration, cytomegalovirus (CMV) esophagitis, herpetic esophagitis, and increased sensitivity to radiation therapy. Despite extensive and deep nature of CMV ulceration, stricture formation is uncommon. There have been anecdotal reports of esophageal strictures secondary to CMV infection in HIV patients. Esophageal stricture has been reported during active CMV ulceration as well as subsequent to successful treatment. Esophageal strictures secondary to CMV have also been reported without prior ulceration. We report a patient with CMV esophagitis presenting with ulceration and stricture who developed total obliteration of esophageal lumen following treatment with gancyclovir.
Sheth
A
A
Division of Gastroenterology and Hepatology, Louisiana State University Health Science Center, Shreveport, Louisiana 71130, USA. asheth@lsuhsc.edu
Boktor
M
M
Diamond
K
K
Lavu
K
K
Sangster
G
G
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D004940:Esophageal Stenosis / Q000209:etiology*; D004941:Esophagitis / Q000150:complications* / Q000188:drug therapy; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D008297:Male; D014456:Ulcer / Q000150:complications* / Q000188:drug therapy
D000998:Antiviral Agents; D015774:Ganciclovir