title: Sequence variation analysis of the prolactin receptor C-terminal region in women with premature ovarian failure.
abstract: Using a mouse model expressing only the PRL receptor short isoform mimicking premature ovarian failure, signaling pathways induced by PRL were analyzed in mouse ovaries. Sequencing of the coding portion of exons 10 and 11, specific to the long and short receptor isoform, respectively, did not revealed any mutation in 101 women with premature ovarian failure.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, U845, Paris, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Bachelot
authors.forename: Justine
authors.initials: J
authors.lastname: Bouilly
authors.forename: Yuchen
authors.initials: Y
authors.lastname: Liu
authors.forename: Diane
authors.initials: D
authors.lastname: Rebourcet
authors.forename: Céline
authors.initials: C
authors.lastname: Leux
authors.forename: Frédérique
authors.initials: F
authors.lastname: Kuttenn
authors.forename: Philippe
authors.initials: P
authors.lastname: Touraine
authors.forename: Nadine
authors.initials: N
authors.lastname: Binart
mesh_terms: D000328:Adult; D000818:Animals; D001483:Base Sequence; D002452:Cell Count; D004252:DNA Mutational Analysis; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D009865:Oocytes / Q000166:cytology / Q000473:pathology; D016649:Primary Ovarian Insufficiency / Q000235:genetics* / Q000473:pathology; D020033:Protein Isoforms / Q000737:chemistry / Q000235:genetics; D017434:Protein Structure, Tertiary / Q000235:genetics; D011981:Receptors, Prolactin / Q000737:chemistry / Q000235:genetics*
chemical_list: D020033:Protein Isoforms; D011981:Receptors, Prolactin