title: Controversies in hybrid banking: attitudes of Swiss public umbilical cord blood donors toward private and public banking.
abstract: OBJECTIVE
  Umbilical cord blood (UCB) stored in public inventories has become an alternative stem cell source for allogeneic stem cell transplantation. The potential use of autologous UCB from private banks is a matter of debate. In the face of the limited resources of public inventories, a discussion on "hybrid" public and private UCB banking has evolved. We aimed to explore the attitudes of the donating parents toward public and private UCB banking.
  
  
  METHODS
  A standardized, anonymous questionnaire was sent to the most recent 621 public UCB donors including items regarding satisfaction with recruitment process, the need for a second consent before release of the UCB unit for stem cell transplantation, and the donors' views on public and private UCB banking. Furthermore, we asked about their views on UCB research.
  
  
  RESULTS
  Of the questionnaires, 48% were returned, and 16% were lost due to mail contact. Of our donors, 95% would donate to the public bank again. As much as 35% of them were convinced that public banking was useful. Whereas 27% had never heard about private UCB banking, 34% discussed both options. Nearly 70% of donors opted for public banking due to altruism and the high costs of private banking. Of our public UCB donors, 81% stated that they did not need a re-consent before UCB release for stem cell transplantation. In case of sample rejection, 53.5% wanted to know details about the particular research project. A total of 9% would not consent.
  
  
  CONCLUSIONS
  Almost all donors would choose public banking again due to altruism and the high costs of private banking. Shortly after donation, mail contact with former UCB donors was difficult. This might be a relevant issue in any sequential hybrid banking.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital Basel, Basel, Switzerland. gmanegold@uhbs.ch
authors.forename: Gwendolin
authors.initials: G
authors.lastname: Manegold
authors.forename: Sandrine
authors.initials: S
authors.lastname: Meyer-Monard
authors.forename: André
authors.initials: A
authors.lastname: Tichelli
authors.forename: Christina
authors.initials: C
authors.lastname: Granado
authors.forename: Irene
authors.initials: I
authors.lastname: Hösli
authors.forename: Carolyn
authors.initials: C
authors.lastname: Troeger
mesh_terms: D001771:Blood Banks; D001782:Blood Donors; D005260:Female; D005312:Fetal Blood; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007258:Informed Consent; D011247:Pregnancy; D017149:Private Sector; D017150:Public Sector; D012959:Socioeconomic Factors; D057905:Stem Cell Research; D011795:Surveys and Questionnaires; D013557:Switzerland