Transurethral injection of bulking agent for treatment of failed mid-urethral sling procedures.
OBJECTIVE
We evaluated the efficacy of transurethral injection (TUI) for the treatment of recurrent or persistent stress urinary incontinence after mid-urethral sling (MUS) procedures.


METHODS
A retrospective study was conducted among 23 women who had undergone TUI for failed MUS using bulking agents, Macroplastique® and Durasphere®. The Sandvik questionnaire, Subjective Symptom Visual Analogue Scale (VAS), Incontinence Quality of Life (I-QOL) assessment, and Benefit, Satisfaction, and Willingness to Continue questionnaire were used to evaluate the efficacy of TUI.


RESULTS
The cure rate was 34.8% for a median follow-up of 10 months. Subjective symptom VAS, total, and all domains of I-QOL scores were significantly improved after TUI. Ninety-two percent of the patients reported a benefit and 77% of the patients were satisfied with the treatment.


CONCLUSIONS
TUI for failed MUS demonstrated a low cure rate but high patient satisfaction, and the procedure was minimally invasive with no significant complications.
Lee
Ha Na
HN
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee
Young-Suk
YS
Han
Ji-Yeon
JY
Jeong
Jae Yong
JY
Choo
Myung-Soo
MS
Lee
Kyu-Sung
KS
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004129:Dimethylpolysiloxanes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004868:Equipment Failure; D005260:Female; D005500:Follow-Up Studies; D005936:Glucans / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007267:Injections; D008875:Middle Aged; D017060:Patient Satisfaction; D012189:Retrospective Studies; D053825:Suburethral Slings; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000628:therapy*; D015040:Zirconium / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D004129:Dimethylpolysiloxanes; D005936:Glucans; C431745:durasphere; C013830:baysilon; D015040:Zirconium