title: An in-vitro comparison between Hemobag and non-Hemobag ultrafiltration methods of salvaging circuit blood following cardiopulmonary bypass.
abstract: Ultrafiltration of the residual cardiopulmonary bypass circuit blood has become one of the most advantageous procedures to maximize autologous whole blood recovery and coagulation management in cardiovascular surgery. In this in-vitro study, the Hemobag technique (HB) was compared to the most common non-Hemobag method (NHB) of hemoconcentrating residual circuit blood. The residual bovine blood from 10 identical extracorporeal circuits was processed by the recirculating HB technique or by a venous reservoir NHB concentration method. Blood component concentrations and hemolysis levels were measured before and after processing. The HB method yielded significantly higher hemoglobin, hematocrit, fibrinogen, albumin, and total protein levels in the final product. There was no significant difference in final product platelet and white blood cell counts, or hemolysis index. HB processing times were substantially shorter at all residual circuit volumes tested. The HB technique resulted in significantly less wasted red blood cells at the end of processing. The recirculating HB method to process residual extracorporeal circuit blood is consistent and superior to the most common single pass concentrating method.
authors.affiliation: New England Perfusion Laboratory, Technology Incubation Program, Global Blood Resources, UCONN Medical Center, Farmington, Connecticut, USA. e26delaney@yahoo.com
authors.forename: Ed
authors.initials: E
authors.lastname: Delaney
authors.forename: David
authors.initials: D
authors.lastname: Rosinski
authors.forename: Harvey
authors.initials: H
authors.lastname: Ellis
authors.forename: Keith A
authors.initials: KA
authors.lastname: Samolyk
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Riley
mesh_terms: D000818:Animals; D002315:Cardiopulmonary Bypass / Q000295:instrumentation* / Q000379:methods*; D002417:Cattle; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006440:Hemofiltration / Q000295:instrumentation* / Q000379:methods*; D014462:Ultrafiltration / Q000295:instrumentation* / Q000379:methods*