title: A case of autoimmune retinopathy associated with thyroid carcinoma.
abstract: OBJECTIVE
  To report a case of autoimmune retinopathy (AIR) associated with a thyroid carcinoma.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 51-year-old Caucasian woman presented with a rapid decline in vision. Initial visual field and immunohistochemical testing revealed autoimmune retinopathy without an apparent underlying malignancy. Conventional local and systemic immunosuppressive therapies failed to halt the progression.
  
  
  RESULTS
  Rituximab treatments were initiated and a slowing of visual loss was seen. Continued surveillance for malignancy revealed a thyroid adenoma, and later a thyroidectomy revealed a thyroid carcinoma.
  
  
  CONCLUSIONS
  This report highlights the unique presentation of AIR associated with a thyroid carcinoma, the need for continued surveillance for malignancy in cases of AIR, and the possible new use of rituximab for the treatment of AIR.
authors.affiliation: Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Mahdi
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Faia
authors.forename: James
authors.initials: J
authors.lastname: Goodwin
authors.forename: Robert B
authors.initials: RB
authors.lastname: Nussenblatt
authors.forename: H Nida
authors.initials: HN
authors.lastname: Sen
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000601:surgery; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002277:Carcinoma / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000069283:Rituximab; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
chemical_list: D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D000069283:Rituximab