Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations.
Sellner
Leopold
L
Capper
David
D
Meyer
Jochen
J
Langhans
Claus-Dieter
CD
Hartog
Christine-Maria
CM
Pfeifer
Heike
H
Serve
Hubert
H
Ho
Anthony D
AD
Okun
Jürgen G
JG
Krämer
Alwin
A
Von Deimling
Andreas
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005977:Glutarates / Q000032:analysis*; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense
D005977:Glutarates; C019417:alpha-hydroxyglutarate; C538784:IDH2 protein, human; D007521:Isocitrate Dehydrogenase; C543588:IDH1 protein, human