title: Lipidized glioblastoma: a rare differentiation pattern.
abstract: We report a rare case of lipidized glioblastoma arising in the tempo-parietal lobe of a 65 year-old woman. The tumor was composed of diffuse sheets of lipidized cells with abundant xanthomatous cytoplasm comprising 60% of the tumor mass. These cells revealed immunopositivity with glial fibrillary acidic protein (GFAP) and the accumulation of lipid was confirmed ultrastructurally. This report highlights the extremely rare lipidized differentiation pattern occurring in glioblastoma and adds observational data to the existing literature on lipid accumulation occurring in glioblastomas.
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. kirtigupta10@yahoo.co.in
authors.forename: Kirti
authors.initials: K
authors.lastname: Gupta
authors.forename: Ivreet
authors.initials: I
authors.lastname: Kalra
authors.forename: Pravin
authors.initials: P
authors.lastname: Salunke
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Vasishta
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology / Q000648:ultrastructure*; D002454:Cell Differentiation; D005260:Female; D005909:Glioblastoma / Q000473:pathology / Q000648:ultrastructure*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008055:Lipids
chemical_list: D008055:Lipids