title: Radiotherapy for extramammary Paget disease of the anogenital region.
abstract: Extramammary Paget disease is a rare condition that most commonly affects the anogenital region in the elderly. The treatment of choice has been surgical excision of the affected area with adequate depth and lateral margins, criteria that cannot always be fulfilled, especially when the vulva, anal canal, or penis are involved. More recently radiotherapy has been suggested as a suitable treatment when surgical excision or other modalities are not appropriate. We report a case of anogenital extramammary Paget disease and the clinical response to treatment with radiotherapy. The aim of this article is to review relevant aspects of radiotherapy as a first-choice curative treatment in specific situations of anogenital extramammary Paget disease in situ.
authors.affiliation: Department of Dermatology, Sagrat Cor University Hospital, Barcelona, Spain. elidilme@hotmail.com
authors.forename: Elisabet
authors.initials: E
authors.lastname: Dilmé-Carreras
authors.forename: Maribel
authors.initials: M
authors.lastname: Iglesias-Sancho
authors.forename: Gemma
authors.initials: G
authors.lastname: Márquez-Balbás
authors.forename: Joaquín
authors.initials: J
authors.lastname: Sola-Ortigosa
authors.forename: Pablo
authors.initials: P
authors.lastname: Umbert-Millet
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D010145:Paget Disease, Extramammary / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy*; D010502:Perineum / Q000473:pathology; D011879:Radiotherapy Dosage; D035583:Rare Diseases; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy*; D016896:Treatment Outcome; D014844:Vulva / Q000473:pathology