[Diuretics-related complications in elderly patients].
Diuretics are well studied and evaluated for their beneficial use in geriatric patients. However those drugs are often used without taking care of subjects condition or functional impairment. Known side effects of those substances may be increased by combinations of multiple drugs. Polypharmacy is a strong risk factor for the incidence of adverse drug reactions (ADR). ADRs are frequently found in combination with the use of diuretics. The remodelling of human body in aging process and uncontrolled therapeutic strategies seem to be causal for that finding. This article tries to work out the potential risk of the usage of those drugs in geriatric patients and its clinical relevance by using literature published in PubMed.
Otto
Ronald
R
Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Austria.
Roller
Regina E
RE
Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Austria.
Iglseder
Bernhard
B
Universitätsklinik für Geriatrie, Paracelsus Medizinische Privatuniversität, Salzburg, Austria.
Dovjak
Peter
P
Abteilung für Akutgeriatrie/Remobilisation, Landeskrankenhaus Gmunden, Gmunden, Austria.
Lechleitner
Monika
M
Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria.
Sommeregger
Ulrike
U
Abteilung für Akutgeriatrie, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wien, Austria.
Benvenuti-Falger
Ursula
U
Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria.
Böhmdorfer
Birgit
B
Anstaltsapotheke, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wien, Austria.
Gosch
Markus
M
Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria. markus.gosch@tilak.at.
D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria; D003681:Dehydration / Q000139:chemically induced; D004232:Diuretics / Q000009:adverse effects* / Q000627:therapeutic use; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D016330:Frail Elderly; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced
D004232:Diuretics