title: [The identification of the "Beijing family" strain of clinical isolated Mycobacterium tuberculosis in the south region of Xinjiang].
abstract: OBJECTIVE
  To identify the Beijing family strain of Mycobacterium tuberculosis (M. tuberculosis) in order to find out the distribution of the Beijing family strain in the south region of Xinjiang, and therefore to provide scientific basis for the prevention and treatment of tuberculosis and the study of molecular epidemiology.
  
  
  METHODS
  From Kashi and Hetian Pulmonary Hospitals and Centers for Disease Control and Prevention, the M. tuberculosis strain were collected and isolated from the sputum of inpatients and registered cases infected with M. tuberculosis, from January to June of 2009. The Beijing family strain was identified by RD105 deletion test. The statistical description was performed using frequency and percentage.
  
  
  RESULTS
  A total of 200 clinical isolates of M. tuberculosis was collected. By means of RD105 deletion test, these strains were typed into 2 groups: the Beijing family and the non-Beijing family. Seventy-nine strains belonged to the Beijing family (79/200, 39.5%) and 121 strains to the non-Beijing family (121/200, 60.5%).
  
  
  CONCLUSIONS
  M. tuberculosis of the Beijing family strain is prevalent at a common level in Uygur living in the south region of Xinjiang. It needs to be investigated whether the Beijing family strain of M. tuberculosis is the predominant strain in the whole region.
authors.affiliation: Department of Pathogen Biology and Immunology, College of Medicine, Shihezi University Xinjiang, Shihezi 832002, China.
authors.forename: Chang-dong
authors.initials: CD
authors.lastname: Wu
authors.forename: Shu
authors.initials: S
authors.lastname: Wen
authors.forename: Li-gu
authors.initials: LG
authors.lastname: Mi
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Cao
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Zipaer
authors.initials: Z
authors.lastname: Aierkenjiang
authors.forename: Tian-mei
authors.initials: TM
authors.lastname: Gong
authors.forename: Yuan-zhi
authors.initials: YZ
authors.lastname: Wang
authors.forename: Yong-xiang
authors.initials: YX
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Yuan
mesh_terms: D015373:Bacterial Typing Techniques; D002681:China / Q000453:epidemiology; D005798:Genes, Bacterial; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D014376:Tuberculosis / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology*