title: [Analytical characteristics of Vitros 3600 analyzer].
abstract: The newly developed, high throughput, Vitros 3600 immunoassay system associates different technologies on board: MicroWell (analytes immunocapture), MicroSensor (visible interference analysis), and Intellicheck (real time process control for analytical error detection). During a three months period, Vitros 3600 system, ease of use, practicability and MicroSensor technology efficiency have been tested using the following assays: betaHCG, troponin, ferritin, aHBcT, HBsAg, aHCV, AFP and CEA. Within-day and within-batch, between-calibration precisions are acceptable. Overall assay correlations versus the methods in use in our laboratory are good, despite small numerical differences that never affect clinical interpretation of the results. We have appreciated the system reliability, reinforced by the ease of use (simple software, on-board VDocs, continuous access to reagent and sample loading, reagent stability, very low noise (60 dB)), the quality of the results, MicroSensor and Intellicheck technologies efficiency, the short maintenance time and its traceability, and the very low liquid waste volume (5 L of liquid waste for 1600 tests). In conclusion and considering its practicability, the Vitros 3600 system is fully validated and well suited for our laboratory.
authors.affiliation: Laboratoire de biologie, Hôpital Robert, Aulnay-sous-Bois.
authors.forename: Irith
authors.initials: I
authors.lastname: Guetta
authors.forename: Valérie
authors.initials: V
authors.lastname: Petit
authors.forename: Isabelle
authors.initials: I
authors.lastname: Ferrando
authors.forename: Lydia
authors.initials: L
authors.lastname: Maisonneuve
authors.forename: Jacques
authors.initials: J
authors.lastname: Mittler
authors.forename: Daniel
authors.initials: D
authors.lastname: Lusina
mesh_terms: D001774:Blood Chemical Analysis / Q000379:methods; D002138:Calibration; D002272:Carcinoembryonic Antigen / Q000097:blood; D005293:Ferritins / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D007202:Indicators and Reagents; D015203:Reproducibility of Results; D014336:Troponin / Q000097:blood; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D002272:Carcinoembryonic Antigen; D006514:Hepatitis B Surface Antigens; D007202:Indicators and Reagents; D014336:Troponin; D000509:alpha-Fetoproteins; D005293:Ferritins; D006854:Hydrocortisone