Switching DISC1 function in neurogenesis: Dixdc1 selects DISC1 binding partners.
The schizophrenia-associated protein DISC1 regulates several steps in neurogenesis. In a recent study published in Neuron, Singh et al. showed how DISC1 and its interacting partner Dixdc1 regulate cell proliferation and cell migration in different manners during embryonic neurogenesis.
Namba
Takashi
T
Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya 466-8550, Japan.
Kaibuchi
Kozo
K