title: [Contribution of animal experimentation to pharmacology].
abstract: Animal experimentation is of considerable importance in pharmacology and cannot yet be avoided when studying complex, highly integrated physiological functions. The use of animals has been drastically reduced in the classical phases of pharmacological research, for example when comparing several compounds belonging to the same pharmacological class. However, animal experiments remain crucial for generating and validating new therapeutic concepts. Three examples of such research, conducted in strict ethical conditions, will be used to illustrate the different ways in which animal experimentation has contributed to human therapeutics.
authors.affiliation: Université de Lyon. jeansassard@yahoo.fr
authors.forename: Jean
authors.initials: J
authors.lastname: Sassard
authors.forename: Michel
authors.initials: M
authors.lastname: Hamon
authors.forename: Francis
authors.initials: F
authors.lastname: Galibert
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D004353:Drug Evaluation, Preclinical; D006801:Humans; D010600:Pharmacology