title: Emergence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae during the years 2000 and 2004 in Helsinki, Finland.
abstract: The molecular epidemiology of 33 Escherichia coli and 81 Klebsiella pneumoniae extended-spectrum beta-lactamase-producing healthcare-associated and community-acquired isolates collected in the Helsinki district during 2000-2004 was investigated. Clonality studies, antimicrobial susceptibility and genotyping of the isolates were performed. Newly emerging CTX-M-producing E. coli and bla(SHV-12)-producing K. pneumoniae isolates were detected. Clonal clusters of both species persisted throughout the study period.
authors.affiliation: National Institute for Health and Welfare, Turku, Finland. sofia.forssten@th1.fi
authors.forename: S D
authors.initials: SD
authors.lastname: Forssten
authors.forename: E
authors.initials: E
authors.lastname: Kolho
authors.forename: A
authors.initials: A
authors.lastname: Lauhio
authors.forename: L
authors.initials: L
authors.lastname: Lehtola
authors.forename: S
authors.initials: S
authors.lastname: Mero
authors.forename: A
authors.initials: A
authors.lastname: Oksaharju
authors.forename: J
authors.initials: J
authors.lastname: Jalava
authors.forename: E
authors.initials: E
authors.lastname: Tarkka
authors.forename: M
authors.initials: M
authors.lastname: Vaara
authors.forename: J
authors.initials: J
authors.lastname: Vuopio-Varkila
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D016172:DNA Fingerprinting; D004926:Escherichia coli / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005387:Finland / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases