Membrane protein fragments reveal both secondary and tertiary structure of membrane proteins.
Structural data on membrane proteins, while crucial to understanding cellular function, are scarce due to difficulties in applying to membrane proteins the common techniques of structural biology. Fragments of membrane proteins have been shown to reflect, in many cases, the secondary structure of the parent protein with fidelity and are more amenable to study. This chapter provides many examples of how the study of membrane protein fragments has provided new insight into the structure of the parent membrane protein.
Yeagle
Philip L
PL
Office of the Dean of Arts & Sciences, Rutgers University, Newark, NJ, USA. pyeagle@andromeda.rutgers.edu
Albert
Arlene D
AD
D009682:Magnetic Resonance Spectroscopy; D008565:Membrane Proteins / Q000737:chemistry*; D008958:Models, Molecular
D008565:Membrane Proteins