Evaluation of toxicity for heart failure therapeutics: studying effects on the QT interval.
Link
Michael G
MG
Main Line Heart Center and Lankenau Institute for Medical Research, Jefferson Medical College, Wynnewood, Pa 19096, USA.
Yan
Gan-Xin
GX
Kowey
Peter R
PR
D000818:Animals; D002317:Cardiovascular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002423:Cause of Death; D016757:Death, Sudden, Cardiac; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000187:drug effects; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000401:mortality; D008297:Male; D011379:Prognosis; D011817:Rabbits; D018570:Risk Assessment; D016019:Survival Analysis; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000401:mortality; D018675:Toxicity Tests
D002317:Cardiovascular Agents