title: Convenient and efficient microwave-assisted synthesis of a methyl derivative of the fused indoloquinoline alkaloid cryptosanguinolentine.
abstract: An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
authors.affiliation: Department of Chemistry, Steve Biko Campus, Durban University of Technology, Durban-4001, South Africa. genganrm@dut.ac.za
authors.forename: Robert M
authors.initials: RM
authors.lastname: Gengan
authors.forename: Pitchai
authors.initials: P
authors.lastname: Pandian
authors.forename: Chandraprakash
authors.initials: C
authors.lastname: Kumarsamy
authors.forename: Palathurai S
authors.initials: PS
authors.lastname: Mohan
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis; D006912:Hydroxyquinolines / Q000138:chemical synthesis*; D026121:Indole Alkaloids / Q000138:chemical synthesis*; D045563:Indolequinones / Q000138:chemical synthesis; D008745:Methylation; D008872:Microwaves; D011798:Quinaldines / Q000138:chemical synthesis*
chemical_list: D000470:Alkaloids; D006912:Hydroxyquinolines; D026121:Indole Alkaloids; D045563:Indolequinones; D011798:Quinaldines; C553173:cryptosanguinolentine; C037073:2-methylquinoline