title: Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats.
abstract: In this study, we investigated the effect of fucoidan polysaccharide sulfuric acid ester (FPS) from Laminaria japonica Aresch (Laminariaceae) on hyperlipidemic rats. FPS notably reduced the concentration of serum total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) of hyperlipidemic rats and increased the concentration of high-density lipoprotein cholesterol (HDL-C) and the activities of lipoprotein lipase (LPL), hepatic lipoprotein (HL), and lecithin cholesterol acyltransferase (LCAT).
authors.affiliation: Department of Oncology, Guangdong Provincial People's Hospital, Guangzhou, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Huang
authors.forename: Kewei
authors.initials: K
authors.lastname: Wen
authors.forename: Xuan
authors.initials: X
authors.lastname: Gao
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D004041:Dietary Fats / Q000008:administration & dosage; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D007795:Laminaria / Q000737:chemistry*; D008055:Lipids / Q000097:blood; D008297:Male; D011134:Polysaccharides / Q000302:isolation & purification / Q000627:therapeutic use*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004041:Dietary Fats; D000960:Hypolipidemic Agents; D008055:Lipids; D011134:Polysaccharides; C007789:fucoidan