title: Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions.
abstract: The clinical, biochemical and genetic features of the conditions known as estrogen-dependent inherited angioedema, estrogen-associated angioedema, hereditary angioedema with normal C-1 inhibitor, type III angioedema, or factor XII angioedema are reviewed. Discussion emphasizes pathogenesis, diagnosis, and management.
authors.affiliation: Division of Clinical Immunology and Allergy, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. binkleyk@smh.toronto.on.ca.
authors.forename: Karen E
authors.initials: KE
authors.lastname: Binkley