title: Giant cell (Temporal) arteritis with anterior ischemic optic neuropathy: a biopsy-proven case in Taiwan.
abstract: Giant cell arteritis with arteritic anterior ischemic optic neuropathy has rarely been diagnosed in Taiwan. Recently, we encountered a 76-year-old Taiwanese patient who presented with right visual impairment and marked pale swelling of his right disc. He also suffered body weight loss, general malaise and many typical manifestations of giant cell arteritis, such as jaw claudication, a tender, non-pulsating engorgement of his temporal arteries, and a highly elevated erythrocyte sedimentation rate and C-reactive protein level. Biopsy of his right superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration. This was a biopsy-proven case of giant cell arteritis with arteritic anterior ischemic optic neuropathy and indicated that although rare, this disease could occur in patients in Taiwan.
authors.affiliation: Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. ckcheng.md@msa.hinet.net
authors.forename: Cheng-Kuo
authors.initials: CK
authors.lastname: Cheng
authors.forename: Chin-Cheng
authors.initials: CC
authors.lastname: Lee
authors.forename: Kai-Han
authors.initials: KH
authors.lastname: Huang
authors.forename: Tzu-En
authors.initials: TE
authors.lastname: Wu
authors.forename: Pai-Huei
authors.initials: PH
authors.lastname: Peng
mesh_terms: D000368:Aged; D001706:Biopsy; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D013700:Giant Cell Arteritis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008297:Male; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage; D013624:Taiwan; D013699:Temporal Arteries / Q000473:pathology; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D002097:C-Reactive Protein; D011239:Prednisolone