Inactivation of human adenovirus by sequential disinfection with an alternative ultraviolet technology and monochloramine.
In an effort to reduce human exposure to adenoviruses through drinking water, we determined the effectiveness of sequential disinfection with an alternative ultraviolet (UV) technology (medium-pressure (MP) UV) and monochloramine. The results of this study showed that MP UV was much more effective than traditional UV technology (low-pressure (LP) UV) against human adenovirus 2 (Ad2). Specifically, an inactivation of approximately 3 log10 was achieved by a dose of 40 mJ/cm2 of MP UV compared to ~1 log10 by the same dose of LP UV. However, because of the ineffective inactivation of Ad2 by monochloramine, a very high dose (40 mJ/cm2) of MP UV and a very large Ct99 value (approximately 1200 mg/L.min) was still needed to achieve a significant inactivation (e.g., 4 log10) of Ad2. Also, it appears that the inactivation of Ad2 by monochloramine is not enhanced by prior exposure to MP UV. Overall, the results of this study indicated that, in spite of the enhanced effectiveness of alternative UV technologies on human adenoviruses, sequential disinfection with an alternative UV technology (MP UV) and monochloramine still may not provide adequate inactivation of human adenoviruses - especially at high pH and low temperature - in drinking water treatment processes.
Shin
Gwy-Am
GA
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, 98105, USA. gwyam@u.washington.edu
Lee
Jung-Keun
JK
D000260:Adenoviruses, Human / Q000187:drug effects* / Q000502:physiology / Q000528:radiation effects*; D002700:Chloramines / Q000494:pharmacology*; D004203:Disinfection / Q000379:methods*; D014466:Ultraviolet Rays; D038301:Virus Inactivation / Q000187:drug effects* / Q000528:radiation effects*
D002700:Chloramines; C030816:chloramine