title: Systolic pressure, diastolic pressure, or pulse pressure as a cardiovascular risk factor in renal disease.
abstract: Chronic kidney disease is a leading global health problem with an increasing prevalence. Hypertension is present in most patients with chronic kidney disease, and hypertension-related nephrosclerosis is a top cause of progressive renal damage and end-stage renal disease. Systolic blood pressure (BP) and pulse pressure, together with nocturnal BP, are the most important factors favoring the progression of renal failure. Consequently, strict control of BP and other cardiovascular risk factors is required, including an adequate degree of suppression of the renin-angiotensin system in every patient.
authors.affiliation: Hypertension Unit, Hospital 12 de Octubre, Av. Cordoba, s/n., 28041, Madrid, Spain. docdonaire@terra.es
authors.forename: José A
authors.initials: JA
authors.lastname: García-Donaire
authors.forename: Luis M
authors.initials: LM
authors.lastname: Ruilope
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000150:complications*; D003971:Diastole; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D007674:Kidney Diseases / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000503:physiopathology; D009400:Nephrosclerosis / Q000503:physiopathology; D015995:Prevalence; D012084:Renin-Angiotensin System / Q000187:drug effects; D012307:Risk Factors; D013599:Systole