[Recent clinical trials in hypertensiology].
The paper presents the results of large randomized clinical trials conducted in recent years, evaluating the efficacy and safety of drugs used to treat hypertension. The results show that angiotensin converting enzyme inhibitors and/or angiotensin receptor antagonists for use as monotherapy and especially in combination with calcium antagonists are effective in controlling blood pressure and in preventing and reducing complications of drugs compared with beta-adrenolytics used as monotherapy or in combination with diuretics. Antihypertensive therapy in the elderly reduces morbidity and mortality from cardiovascular causes.
Kurlapska
Ewelina
E
Wojskowy Szpital Kliniczny z Poliklinika w Bydgoszczy, Klinika Kardiologii i Kardiochirurgii. kardiologia@10wsk.mil.pl
Goch
Jan Henryk
JH
Kasprzak
Krzysztof
K
Goch
Aleksander
A
D000368:Aged; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic
D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers