Multicentric reticulohistiocytosis.
A 50-year-old male presented with fever, joint pain and skin lesions since eight months. Examination showed multiple papules and nodules with periarticular predisposition. Swelling of knees and elbows with flexion deformity of distal interphalangeal joints was present. Investigations revealed anemia and raised ESR. Histopathology was pathognomonic of multicentric reticulohistiocytosis. Patient was treated with bisphosphonates along with systemic steroids and methotrexate to which he responded well.
Kaul
Arvind
A
Department of Dermatology, Sassoon Hospital, Pune-1, Maharashtra, India. arvindkaul16@gmail.com
Tolat
Sunil N
SN
Belgaumkar
Vasudha
V
Mhaske
Chandrakant B
CB
D004164:Diphosphonates / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015616:Histiocytosis, Non-Langerhans-Cell / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007592:Joint Diseases / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology*; D013256:Steroids / Q000627:therapeutic use
D004164:Diphosphonates; D007166:Immunosuppressive Agents; D013256:Steroids; D008727:Methotrexate