title: One-step synthesis of quinazolino[3,2-a]quinazolinones via palladium-catalyzed domino addition/carboxamidation reactions.
abstract: A highly efficient palladium-catalyzed domino process has been developed for the synthesis of quinazolino[3,2-a]quinazolinones by forming five new bonds in a single step. Despite the high density and variety of functional groups on the substrates, the tetracyclic quinazolinones were obtained in good to excellent yields.
authors.affiliation: Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada, K1N 6N5.
authors.forename: Fanlong
authors.initials: F
authors.lastname: Zeng
authors.forename: Howard
authors.initials: H
authors.lastname: Alper