title: Insecticidal constituents from the argentine liverwort Plagiochila bursata.
abstract: The new 2,3-secoaromadendrane 1, together with the known compounds plagiochilines A and M (2 and 3, resp.), fusicogigantone A (4), and 1,4-dimethylazulene (5) were isolated from an Argentine collection of the liverwort Plagiochila bursata. Structures were elucidated by extensive 1D- and 2D-NMR studies. Compounds 2 and 4, incorporated to the larval diet at 100 microg per g of diet, reduced the larval growth of Spodoptera frugiperda (Lepidoptera: Noctuidae) by 66+/-29% and 25+/-8% and produced 55 and 75% larval mortality at early instars and 20 and 25% pupal mortality, respectively. Treatment with compound 2 also produced abdomen and wing malformation in adults leading to impossibility to mate.
authors.affiliation: Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000 Tucumán, Argentina.
authors.forename: Marta
authors.initials: M
authors.lastname: Ramírez
authors.forename: Norma
authors.initials: N
authors.lastname: Kamiya
authors.forename: Susana
authors.initials: S
authors.lastname: Popich
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Asakawa
authors.forename: Alicia
authors.initials: A
authors.lastname: Bardón
mesh_terms: D000818:Animals; D035926:Hepatophyta / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D011679:Pupa / Q000254:growth & development; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D018411:Spodoptera / Q000254:growth & development*
chemical_list: D007306:Insecticides; D012717:Sesquiterpenes