Preparation and evaluation of molecularly imprinted solid-phase micro-extraction fibers for selective extraction of phthalates in an aqueous sample.
A novel molecularly imprinted polymer (MIP) that was applied to a solid-phase micro-extraction (SPME) device, which could be coupled directly to gas chromatograph and mass spectrometer (GC/MS), was prepared using dibutyl phthalate (DBP) as the template molecule. The characteristics and application of this fiber were investigated. Electron microscope images indicated that the MIP-coated solid-phase micro-extraction (MI-SPME) fibers were homogeneous and porous. The extraction yield of DBP with the MI-SPME fibers was higher than that of the non-imprinted polymer (NIP)-coated SPME (NI-SPME) fibers. The MI-SPME fibers had a higher selectivity to other phthalates that had similar structures as DBP. A method was developed for the determination of phthalates using MI-SPME fibers coupled with GC/MS. The extraction conditions were optimized. Detection limits for the phthalate samples were within the range of 2.17-20.84 ng L(-1). The method was applied to five kinds of phthalates dissolved in spiked aqueous samples and resulted in recoveries of up to 94.54-105.34%, respectively. Thus, the MI-SPME fibers are suitable for the extraction of trace phthalates in complicated samples.
He
Juan
J
School of Chemistry and Chemical Engineering, Henan University of, Technology, LianHua Road, Zhengzhou 450051, China. juanhe@haut.edu.cn
Lv
Ruihe
R
Zhan
Haijun
H
Wang
Huizhi
H
Cheng
Jie
J
Lu
Kui
K
Wang
Fengcheng
F
D003993:Dibutyl Phthalate / Q000138:chemical synthesis / Q000737:chemistry*; D008567:Membranes, Artificial; D054802:Molecular Imprinting; D010795:Phthalic Acids / Q000302:isolation & purification*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D016062:Porosity; D052617:Solid Phase Microextraction / Q000379:methods*; D012996:Solutions; D013499:Surface Properties
D008567:Membranes, Artificial; D010795:Phthalic Acids; D011108:Polymers; D012996:Solutions; D003993:Dibutyl Phthalate