title: [Long-term clinical observation of an accommodative 1CU after implantation].
abstract: OBJECTIVE
  To evaluate the clinical effectiveness and accommodative range after implanting the 1CU.
  
  
  METHODS
  It was a prospective case series study. From March in 2004 to December in 2007, 23 cases (28 eyes) had phacoemulsification and implantation of 1CU (HumanOptics). Naked and best corrected distant acuity, Naked acuity at 35 cm and best corrected near, the amplitude of accommodation measured with subjective and objective techniques and the change in the anterior chamber depth were measured at 3-6 months, 18-24 months and over 36 months after surgery.
  
  
  RESULTS
  After implantation, the 1CU had good centered and stable and no IOL-specific complications. Naked distant acuity of the three groups are 0.84+/-0.23, 0.81+/-0.19 and 0.78+/-0.17, between them there are no significantly statistical differences (F=0.759, P>0.05). The best corrected distant acuity of the three groups were 0.97+/-0.13, 0.99+/-0.17 and 1.00+/-0.17, between them there are no significantly statistical differences (F=0.17, P>0.05). The near acuity at 35 cm was 0.66+/-0.24, 0.52+/-0.14 and 0.47+/-0.12, between them there are significantly statistical differences (F=9.312, P<0.01). The best corrected near acuity were 0.97+/-0.13, 0.94+/-0.22 and 0.90+/-0.21, between them there are no significantly statistical differences (F=0.915, P>0.05). The accommodative range measured with subjective were 0.89+/-0.34, 0.72+/-0.17 and 0.56+/-0.16, between them there are significantly statistical differences (F=13.43, P<0.01). The accommodative range measured with objective were 3.58+/-0.54, 3.01+/-0.89 and 2.50+/-0.54, between them there were significantly statistical differences (F=17.886, P<0.01). The anterior chamber depth measured by application of 2% pilocarpine eyedrops were 0.88+/-0.40, 0.54+/-0.23 and 0.33+/-0.20, between them there were significantly statistical differences (F=26.589, P<0.01).
  
  
  CONCLUSIONS
  The eyes with 1CU have good visual acuity and increased accommodative range more than the single-focus IOL. With the extension of time after surgery, the ability of 1CU regulation gradually declines, and nears point swift away gradually.
authors.affiliation: Department of Ophthalmology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. drliuxinquan@hotmail.com
authors.forename: Xin-quan
authors.initials: XQ
authors.lastname: Liu
authors.forename: Ming-fei
authors.initials: MF
authors.lastname: Li
authors.forename: Ming-hua
authors.initials: MH
authors.lastname: Guo
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
mesh_terms: D000065:Accommodation, Ocular; D000368:Aged; D002386:Cataract / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies