title: A mild and facile one-pot synthesis of N-methyl-acyl-pyrroles.
abstract: N-Methyl-3-acylpyrroles were synthesized via a multicomponent reaction of dimethylacetylene dicarboxylate (DMAD), N-methylhydroxylamine and acylchlorides in the presence of KHCO(3). For comparison both conventional and microwave protocols were examined in this procedure. The reaction is clean and gives the products in good to excellent yields under conventional heating conditions at 40 degrees C in anhydrous dichloromethane.
authors.affiliation: Department of Chemistry, Faculty of Sciences, Azarbaijan University of Tarbiat Moallem, Tabriz, Iran. h-valizadeh@azaruniv.edu
authors.forename: Hassan
authors.initials: H
authors.lastname: Valizadeh
authors.forename: Ashraf
authors.initials: A
authors.lastname: Fakhari
mesh_terms: D003998:Dicarboxylic Acids / Q000737:chemistry; D019811:Hydroxylamine / Q000737:chemistry; D008872:Microwaves; D011758:Pyrroles / Q000138:chemical synthesis*
chemical_list: D003998:Dicarboxylic Acids; D011758:Pyrroles; D019811:Hydroxylamine