title: Calcification of hydrophilic acrylic intraocular lenses in combined phacovitrectomy surgery.
abstract: Two cases of postoperative intraocular lens (IOL) calcification in patients implanted with the Akreos Adapt IOL at the time of combined phacovitrectomy are described, along with clinical review of all patients implanted with this IOL type at our institution between November 2006 and September 2008. The IOLs explanted from the 2 cases were examined using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). The SEM of the explanted IOLs showed crystalline anterior surface and subsurface deposits; by EDX, the deposits showed high concentrations of calcium and phosphorous, consistent with calcium apatite. Twenty patients (20 eyes) attended for cohort review, and none showed IOL opacification. The reason calcification occurred in the 2 cases remains unknown, but clinicians should be aware of this potential complication.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Oxford Eye Hospital, United Kingdom.
authors.forename: Nathan J
authors.initials: NJ
authors.lastname: Walker
authors.forename: Mario J
authors.initials: MJ
authors.lastname: Saldanha
authors.forename: John A H
authors.initials: JA
authors.lastname: Sharp
authors.forename: Hamid
authors.initials: H
authors.lastname: Porooshani
authors.forename: Brendan M
authors.initials: BM
authors.lastname: McDonald
authors.forename: David J P
authors.initials: DJ
authors.lastname: Ferguson
authors.forename: Chetan K
authors.initials: CK
authors.lastname: Patel
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D002114:Calcinosis / Q000209:etiology*; D002118:Calcium / Q000032:analysis; D020878:Device Removal; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D018918:Phacoemulsification; D010758:Phosphorus / Q000032:analysis; D011183:Postoperative Complications; D014821:Vitrectomy
chemical_list: D000180:Acrylic Resins; D010758:Phosphorus; D002118:Calcium