title: Heart Rhythm UK position statement on clinical indications for implantable cardioverter defibrillators in adult patients with familial sudden cardiac death syndromes.
abstract: Whilst the decision regarding defibrillator implantation in a patient with a familial sudden cardiac death syndrome is likely to be most significant for any particular individual, the clinical decision-making process itself is complex and requires interpretation and extrapolation of information from a number of different sources. This document provides recommendations for adult patients with the congenital Long QT syndromes, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, hypertrophic cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy. Although these specific conditions differ in terms of clinical features and prognosis, it is possible and logical to take an approach to determining a threshold for implantable cardioveter-defibrillator implantation that is common to all of the familial sudden cardiac death syndromes based on estimates of absolute risk of sudden death.
authors.affiliation: University of Manchester, Manchester, UK. clifford.garratt@cmmc.nhs.uk
authors.forename: Clifford J
authors.initials: CJ
authors.lastname: Garratt
authors.forename: Perry
authors.initials: P
authors.lastname: Elliott
authors.forename: Elijah
authors.initials: E
authors.lastname: Behr
authors.forename: A John
authors.initials: AJ
authors.lastname: Camm
authors.forename: Campbell
authors.initials: C
authors.lastname: Cowan
authors.forename: Stephanie
authors.initials: S
authors.lastname: Cruickshank
authors.forename: Andrew
authors.initials: A
authors.lastname: Grace
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Griffith
authors.forename: Anne
authors.initials: A
authors.lastname: Jolly
authors.forename: Pier
authors.initials: P
authors.lastname: Lambiase
authors.forename: Pascal
authors.initials: P
authors.lastname: McKeown
authors.forename: Peter
authors.initials: P
authors.lastname: O'Callagan
authors.forename: Graham
authors.initials: G
authors.lastname: Stuart
authors.forename: Hugh
authors.initials: H
authors.lastname: Watkins
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000453:epidemiology / Q000628:therapy*; D009202:Cardiomyopathies / Q000453:epidemiology / Q000628:therapy*; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000517:prevention & control*; D017147:Defibrillators, Implantable / Q000592:standards*; D006801:Humans; D006113:United Kingdom