[Diagnostic value of serum procalcitonin and C-reaction protein in acute exacerbation of chronic bronchitis].
OBJECTIVE
To evaluate the diagnostic value of serum procalcitonin (PCT) and C-reactive protein (CRP) in patients with acute exacerbation of chronic bronchitis.


METHODS
The PCT and CRP levels were detected in 56 patients with acute exacerbation of chronic bronchitis and 58 healthy control subjects.


RESULTS
The serum PCT level and positivity rate were significantly higher in the case group than in the control group (P<0.05); the serum CRP level was also significantly higher in the case group (P<0.05), but the positivity rate of CRP was similar between the two groups (P>0.05). The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy rate of PCT were higher than those of CRP.


CONCLUSIONS
Serum PCT is more sensitive than CRP in the diagnoses of acute exacerbation of chronic bronchitis, and can be used as a specific indicator for monitoring the condition of the patients.
Hu
Xiao-Jia
XJ
Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. gz198@163.com
Zhou
Fang
F
Qiu
Yu-Rong
YR
Li
Qiang
Q
D000293:Adolescent; D000328:Adult; D029481:Bronchitis, Chronic / Q000097:blood / Q000175:diagnosis*; D002097:C-Reactive Protein / Q000378:metabolism*; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011498:Protein Precursors / Q000097:blood*; D012680:Sensitivity and Specificity; D055815:Young Adult
C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D002097:C-Reactive Protein; D015740:Calcitonin Gene-Related Peptide