title: Genetic manipulation in Bacillus thuringiensis for strain improvement.
abstract: Bacillus thuringiensis (Bt) has been used as a biopesticide in agriculture, forestry and mosquito control because of its advantages of specific toxicity against target insects, lack of polluting residues and safety to non-target organisms. The insecticidal properties of this bacterium are due to insecticidal proteins produced during sporulation. Despite these ecological benefits, the use of Bt biopesticides has lagged behind the synthetic chemicals. Genetic improvement of Bt natural strains, in particular Bt recombination, offers a promising means of improving efficacy and cost-effectiveness of Bt-based bioinsecticide products to develop new biotechnological applications.
authors.affiliation: Facultad de Ciencias Químicas de la Benemérita Universidad Autónoma de Puebla, 72570 Puebla, Pue, Mexico. estisan@siu.buap.mx
authors.forename: Estibaliz
authors.initials: E
authors.lastname: Sansinenea
authors.forename: Candelario
authors.initials: C
authors.lastname: Vázquez
authors.forename: Aurelio
authors.initials: A
authors.lastname: Ortiz
mesh_terms: D000818:Animals; D001413:Bacillus thuringiensis / Q000235:genetics* / Q000378:metabolism* / Q000472:pathogenicity; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D053898:Biosynthetic Pathways / Q000235:genetics*; D004731:Endotoxins / Q000096:biosynthesis* / Q000235:genetics; D005818:Genetic Engineering; D006460:Hemolysin Proteins / Q000096:biosynthesis* / Q000235:genetics; D007300:Insect Control / Q000379:methods; D007313:Insecta / Q000382:microbiology*; D010572:Pest Control, Biological / Q000379:methods; D011995:Recombination, Genetic
chemical_list: D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D004731:Endotoxins; D006460:Hemolysin Proteins; C030956:insecticidal crystal protein, Bacillus Thuringiensis