title: Fragrance mix reactions and lime allergic contact dermatitis.
abstract: Allergic contact dermatitis due to citrus fruits is rare, but has been reported in cooks and bartenders. We report an interesting case of a bartender with hand dermatitis who had an allergic contact sensitivity to lime peel, fragrance mix I, and fragrance mix II. Most reported cases of citrus peel allergy are due to d-limonene, which makes up the majority of the peel oil. However, our patient had an allergic reaction to geraniol, which is a minor component of the peel oil and is present in fragrance mix I. It is important to consider a contact sensitivity to citrus in patients who have positive reactions to fragrance mix I and II and who are occupationally exposed to citrus fruits. An initial positive reaction to fragrance mixes should prompt further testing to citrus in these individuals.
authors.affiliation: Department of Dermatology, Oregon Health & State University, Portland, OR, USA
authors.forename: Amy
authors.initials: A
authors.lastname: Swerdlin
authors.forename: David
authors.initials: D
authors.lastname: Rainey
authors.forename: Frances J
authors.initials: FJ
authors.lastname: Storrs
mesh_terms: D000080462:Acyclic Monoterpenes; D032082:Citrus aurantiifolia / Q000009:adverse effects*; D053138:Cyclohexenes / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D006229:Hand Dermatoses / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D000077222:Limonene; D008875:Middle Aged; D010328:Patch Tests; D010476:Perfume / Q000009:adverse effects*; D013729:Terpenes / Q000009:adverse effects
chemical_list: D000080462:Acyclic Monoterpenes; D053138:Cyclohexenes; D010476:Perfume; D013729:Terpenes; D000077222:Limonene; C007836:geraniol