Bullous lupus: an unusual initial presentation of systemic lupus erythematosus in an adolescent girl.
Bullous systemic lupus erythematosus is a subepidermal blistering disease that occurs only rarely in a subset of patients with systemic lupus erythematosus and even less commonly in pediatric patients. Autoimmunity in bullous systemic lupus erythematosus is characterized by the presence of circulating anti-type VII collagen antibodies. We report here a case of a child whose initial systemic lupus erythematosus presentation was a diffuse bullous eruption.
Tincopa
Monica
M
Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Puttgen
Katherine B
KB
Sule
Sangeeta
S
Cohen
Bernard A
BA
Gerstenblith
Meg R
MR
D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D024143:Collagen Type VII / Q000276:immunology; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008775:Methylprednisolone / Q000627:therapeutic use; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology
D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D024143:Collagen Type VII; D006886:Hydroxychloroquine; D003622:Dapsone; D009173:Mycophenolic Acid; D011241:Prednisone; D008775:Methylprednisolone