title: Relationship between serum uric Acid levels, metabolic syndrome, and arterial stiffness in korean.
abstract: OBJECTIVE
  Associations have been reported between the serum uric acid (SUA) level, metabolic syndrome (MS), and atherosclerosis. We have determined the relationship between the SUA level, MS, and arterial stiffness in Korean.
  
  
  METHODS
  Cross-sectional data from 1,276 adults who underwent routine laboratory tests and pulse wave velocity (PWV) measurements during a health check-up were analyzed in a gender-specific manner. None of the participants had atherosclerotic cardiovascular disease, diabetes, renal disease, or systemic disease, or were under treatment which would affect SUA levels, or taking medications for hypertension or dyslipidemia.
  
  
  RESULTS
  After adjustment for age, smoking status, total cholesterol (TC), and creatinine, the odds ratios (ORs, 95% confidence interval) of gender-specific quartiles of SUA for MS were 1.0, 1.28 (0.66-2.47), 1.46 (0.76-2.82), and 2.21 (1.15-4.26) in females, and 1.0, 1.33 (0.82-2.17), 1.60 (0.96-2.66), and 2.03 (1.21-3.40) in males. However, after adjustment for waist circumference, there were no significant differences in the ORs among the SUA quartile groups in females and males (both, p=NS). The Pearson's correlation coefficients for the relationship between SUA levels and heart-femoral (hf) PWVs or brachial-ankle (ba) PWVs were not significant in females and males (r=0.054 and r=0.015, respectively, in females; r=-0.036 and r=-0.015, respectively, in males; all, p=NS).
  
  
  CONCLUSIONS
  An elevated SUA level is associated with abdominal obesity among the MS components, but the SUA level is not associated with PWV in females or males.
authors.affiliation: Department of Internal Medicine, Dongguk University College of Medicine, Ilsan Hospital, Goyang, Korea.
authors.forename: Ji Hyon
authors.initials: JH
authors.lastname: Lim
authors.forename: Young-Kwon
authors.initials: YK
authors.lastname: Kim
authors.forename: Yong-Seok
authors.initials: YS
authors.lastname: Kim
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Na
authors.forename: Moo-Yong
authors.initials: MY
authors.lastname: Rhee
authors.forename: Myoung-Mook
authors.initials: MM
authors.lastname: Lee