Antifungal activity of glyceollins isolated from soybean elicited with Aspergillus sojae.
The aim of this study was to examine the efficacy of glyceollins isolated from soybean seeds elicited with Aspergillus sojae for its antifungal potential. Glyceollins I, II, and III were determined by HPLC-MS analysis. The glyceollins (200 and 600 microg/disk) revealed remarkable antifungal effect against Fusarium oxysporum , Phytophthora capsici, Sclerotinia sclerotiorum, and Botrytis cinerea, within the growth inhibition range of 10.9-61.0%, along with their respective MIC values ranging from 25 to 750 microg/mL. The glyceollins also had a strong detrimental effect on spore germination of all tested plant pathogens along with concentration- as well as time-dependent kinetic inhibition of P. capsici. Thus, the results obtained in this study demonstrate that glyceollins derived from soybean seeds elicited with A. sojae possess a wide range of fungicidal activity and could become an alternative to synthetic fungicides for controlling certain important fungal diseases.
Kim
Hyo Jung
HJ
School of Applied Bioscience, Kyungpook National University, Deagu 702-701, Republic of Korea.
Suh
Hwa-Jin
HJ
Lee
Choong Hwan
CH
Kim
Jeong Hwan
JH
Kang
Sun Chul
SC
Park
Sunmin
S
Kim
Jong-Sang
JS
D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000502:physiology*; D008826:Microbial Sensitivity Tests; D036343:Pterocarpans / Q000494:pharmacology*; D013025:Glycine max / Q000737:chemistry* / Q000382:microbiology
D000935:Antifungal Agents; D036343:Pterocarpans; C017343:glyceollin