A novel antimicrobial agent from the leaves of Peltophorum vogelianum (Benth.).
The methanolic extract of the leaves of Peltophorum vogelianum (Caesalpiniaceae) afforded a new phytoconstituent, 2-methoxy-4,5-dihydroxy-1(7,8-dihydroxyethylene)-8-beta-D-glucuropyranoside named as peltophorumyl-beta-D-glucuropyranoside (5), along with four known phytoconstituents, 1-pentatriacontanol (1), friedelin (2), beta-sitosterol (3) and beta-sitosterol-beta-D-glucopyranoside (4), which have not been isolated previously from this plant. Their structures were established on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC and MS). Moreover, compound 5 showed significant antimicrobial activity.
Parveen
Mehtab
M
Department of Chemistry, Aligarh Muslim University, Aligarh-202002, Uttar Pradesh, India. mehtab_organic@rediffmail.com
Ghalib
Raza Murad
RM
Khanam
Zakia
Z
Mehdi
Sayed Hasan
SH
Ali
Mohammed
M
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002850:Chromatography, Gel; D003460:Crystallization; D007887:Fabaceae / Q000737:chemistry*; D007194:India; D013058:Mass Spectrometry; D000432:Methanol; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000890:Anti-Infective Agents; D010936:Plant Extracts; D012503:Saponins; D000432:Methanol