Membranous nephropathy and Kimura's disease manifesting a hip mass. A case report with literature review.
We report a case of Kimura's disease with membranous nephropathy. A 15-year-old Japanese boy was referred to our hospital with proteinuria and a subcutaneous mass in the hip. Renal biopsy demonstrated secondary membranous nephropathy (MN) with mild mesangial proliferation and some electron-dense deposits in the mesangium. Laboratory tests revealed eosinophilia and a high level of serum IgE, which are common findings in Kimura's disease. A biopsy of the mass in the hip was performed and Kimura's disease was diagnosed. Treatment with oral prednisolone resulted in a decrease of proteinuria and regression of the subcutaneous mass. Kimura's disease should be included in the differential diagnosis of secondary MN.
Obata
Yoko
Y
The Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan.
Furusu
Akira
A
Nishino
Tomoya
T
Ichinose
Hiroshi
H
Ohnita
Aki
A
Iwasaki
Keisuke
K
Taguchi
Takashi
T
Kohno
Shigeru
S
D000293:Adolescent; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D015433:Glomerulonephritis, Membranous / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006615:Hip / Q000473:pathology*; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
D011239:Prednisolone