title: Effects of chloride, bromide, and iodide upon decomposition of nucleosides induced by ultrasound in neutral solution.
abstract: When the ultrasound of 42 kHz was irradiated on a neutral mixture of 2'-deoxycytidine, 2'-deoxyguanosine, 2'-deoxythymidine, and 2'-deoxyadenosine, concentrations of all the nucleosides decreased. Addition of NaCl to the system had no effect. NaBr suppressed the reactions for all the nucleosides, but the efficiency of 2'-deoxyguanosine was low. NaI suppressed the reactions for all the nucleosides more effectively. A comparison with the results of the effects of halides on the reaction of nucleosides by a Fenton system suggested that only half of the nucleoside damage in the ultrasound-irradiated solution was caused by hydroxyl radicals formed from water by the sonication.
authors.affiliation: School of Pharmacy, Shujitsu University, Okayama, Japan. tsuzuki@shujitsu.ac.jp
authors.forename: Toshinori
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamada
authors.forename: Michiyo
authors.initials: M
authors.lastname: Inukai
mesh_terms: D001965:Bromides / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D009705:Nucleosides / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*; D017670:Sodium Compounds / Q000737:chemistry*; D012974:Sodium Iodide / Q000737:chemistry*; D014465:Ultrasonics
chemical_list: D001965:Bromides; D009705:Nucleosides; D017670:Sodium Compounds; D012965:Sodium Chloride; D012974:Sodium Iodide; C027938:sodium bromide