Insecticidal constituents from the argentine liverwort Plagiochila bursata.
The new 2,3-secoaromadendrane 1, together with the known compounds plagiochilines A and M (2 and 3, resp.), fusicogigantone A (4), and 1,4-dimethylazulene (5) were isolated from an Argentine collection of the liverwort Plagiochila bursata. Structures were elucidated by extensive 1D- and 2D-NMR studies. Compounds 2 and 4, incorporated to the larval diet at 100 microg per g of diet, reduced the larval growth of Spodoptera frugiperda (Lepidoptera: Noctuidae) by 66+/-29% and 25+/-8% and produced 55 and 75% larval mortality at early instars and 20 and 25% pupal mortality, respectively. Treatment with compound 2 also produced abdomen and wing malformation in adults leading to impossibility to mate.
Ramírez
Marta
M
Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000 Tucumán, Argentina.
Kamiya
Norma
N
Popich
Susana
S
Asakawa
Yoshinori
Y
Bardón
Alicia
A
D000818:Animals; D035926:Hepatophyta / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000254:growth & development; D011679:Pupa / Q000254:growth & development; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D018411:Spodoptera / Q000254:growth & development*
D007306:Insecticides; D012717:Sesquiterpenes