[Import and local transmission of Haemophilus ducreyi].
Chancroid is a sexually transmitted disease characterized by painful ulcers with a soft margin, necrotic base and purulent exudate. Previously, only sporadic, imported cases have been reported in Denmark. The bacterium is difficult to culture and novel polymerase chain reaction (PCR)-based methods for direct demonstration of bacterial DNA have facilitated rapid verification of the clinical diagnosis. We report two cases which demonstrate import and subsequent local transmission in Denmark. In both cases, the clinical diagnosis was rapidly verified by a combined PCR testing for multiple causes of venereal ulcers.
Knudsen
Troels Bygum
TB
Dermato-Venerologisk Afdeling, Bispebjerg Hospital, 2400 København NV. tbygum@gmail.com
Sand
Carsten
C
Jensen
Jørgen Skov
JS
D000328:Adult; D002602:Chancroid / Q000175:diagnosis / Q000473:pathology / Q000635:transmission*; D003718:Denmark; D003937:Diagnosis, Differential; D006191:Haemophilus ducreyi / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000208:ethnology; D016133:Polymerase Chain Reaction; D012749:Sexually Transmitted Diseases / Q000175:diagnosis