Rheumatoid granuloma of the cervix and vagina: a challenging diagnosis and treatment.
BACKGROUND
Granulomas of the female genital tract are rare and usually occur after operative procedures.


METHODS
A patient with rheumatoid arthritis presented with vaginal discharge and bleeding with ulcerative, red, friable lesions of the cervix, which extended to the bladder floor and the right upper vaginal wall. Cervical biopsy was highly suggestive of rheumatoid nodules. This prompted revision of the diagnosis of tuberculosis, which was suspected several months earlier when pulmonary and renal lesions were noted. The cervico-vaginal lesions did not respond to local steroid treatment and improved when the systemic steroid dose was increased; however, they recurred on tapering the dose.


CONCLUSIONS
Rheumatoid nodules can occur in the genital tract, which poses diagnostic and treatment challenges.
Usta
Ihab M
IM
From the Departments of Obstetrics and Gynecology, Internal Medicine, and Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Uthman
Imad W
IW
Kattar
Mireille
M
Nassar
Anwar H
AH
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006099:Granuloma / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D001745:Urinary Bladder Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D014623:Vaginal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology