title: [Bilateral emphysematous pyelonephritis caused by Candida glabrata: An exceptional entity].
abstract: Acute emphysematous pyelonephritis (AEP) is a severe form of urinary tract infection. It occurs usually in diabetics. The most concerned agents are the Gram-negative bacilli. We report a first case of bilateral AEP due to Candida glabrata, occurred in a 64-year-old diabetic woman. The clinical presentation started with fever and abdominal pains, without signs of urinary tract infection. Within six hours, the patient had developed a septic shock with renal failure and ketoacidosis. The diagnosis was confirmed by CT scan and the pathogen was isolated in urine. Despite antibiotic and antifungal treatment, she died from a septic shock. Acute emphysematous pyelonephritis due to Candida species is rare. However, the addition of antifungal therapy seems justified if a severe emphysematous pyelonephritis is associated with risk factors of Candida infection.
authors.affiliation: Service de maladies infectieuses, CHU Hédi Chaker, route El Aïn Km 0,5, 3029 Sfax, Tunisie.
authors.forename: Hajer
authors.initials: H
authors.lastname: Harrabi
authors.forename: Chakib
authors.initials: C
authors.lastname: Marrakchi
authors.forename: Emna
authors.initials: E
authors.lastname: Daoud
authors.forename: Emna
authors.initials: E
authors.lastname: Elleuch
authors.forename: Boussayma
authors.initials: B
authors.lastname: Hammami
authors.forename: Imed
authors.initials: I
authors.lastname: Maâloul
authors.forename: Dorra
authors.initials: D
authors.lastname: Lahiani
authors.forename: Jamel
authors.initials: J
authors.lastname: Mnif
authors.forename: Mounir
authors.initials: M
authors.lastname: Ben Jemâa
mesh_terms: D041221:Candida glabrata; D002177:Candidiasis / Q000150:complications*; D004646:Emphysema / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D011704:Pyelonephritis / Q000382:microbiology*; D012772:Shock, Septic / Q000382:microbiology