Comparison of serum levels and the placental expression of resistin between patients with preeclampsia and normal pregnant women.
OBJECTIVE
The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression.


METHODS
Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry.


RESULTS
Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression.


CONCLUSIONS
The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.
Seol
Hyun-Joo
HJ
Department of Obstetrics and Gynecology, College of Medicine, Kyung Hee University, Seoul, South Korea.
Oh
Min-Jeong
MJ
Yeo
Min-Koo
MK
Kim
Aeree
A
Lee
Eung-Seok
ES
Kim
Hai-Joong
HJ
D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010920:Placenta / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000097:blood / Q000378:metabolism*; D011247:Pregnancy; D052243:Resistin / Q000378:metabolism*
D052243:Resistin