title: Prognostic factors in pediatric acute myeloid leukemia.
abstract: Acute myeloid leukemia (AML), a heterogeneous group of diseases with variable responses to the same therapy, comprises nearly a quarter of childhood acute leukemias. Although historically very few prognostic markers have been incorporated into therapeutic decision making in AML, recent advances in technology have enabled identification of numerous factors associated with disease outcome. This review provides a detailed analysis of most clinically relevant factors associated with disease outcome in childhood AML.
authors.affiliation: Children's Mercy Hospital, Kansas City, MO 64108, USA. maradhi@cmh.edu
authors.forename: Mohamed
authors.initials: M
authors.lastname: Radhi
authors.forename: Soheil
authors.initials: S
authors.lastname: Meshinchi
authors.forename: Alan
authors.initials: A
authors.lastname: Gamis
mesh_terms: D000367:Age Factors; D014408:Biomarkers, Tumor; D015992:Body Mass Index; D002648:Child; D003582:Cytogenetics; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D011110:Polymorphism, Genetic; D011379:Prognosis; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D014408:Biomarkers, Tumor