title: High-energy neodymium laser radiation for the treatment of face cutaneous melanoma.
abstract: This study retrospectively evaluated the curative efficacy of two powerful pulsed Neodymium (Nd) lasers (lambda = 1060 nm, pulse duration 1 and 4.5 msec, maximum pulse energy 700 and 1000 J, respectively) for the treatment of 47 patients with histologically confirmed stage I cutaneous melanoma of the face who were followed-up 5 years and more. The estimated 5-year survival rate was 82.9%. Regional and distant metastases developed in 23.4% of the patients. There were no cases with local recurrences. High-energy pulsed Nd laser radiation is effective in treating flat and / or slightly raised cutaneous stage I facial melanomas, while the therapeutic result is also accompanied by positive cosmetic result.
authors.affiliation: Laboratory of High Energies, N.N. Petrov Research Institute of Oncology, 68 Leningradskaya Street, Pesochny, 197758 St. Petersburg, Russia. oncl1@rion.spb.ru
authors.forename: K G
authors.initials: KG
authors.lastname: Moskalik
authors.forename: A P
authors.initials: AP
authors.lastname: Kozlov
authors.forename: E V
authors.initials: EV
authors.lastname: Demin
mesh_terms: D005153:Facial Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D008545:Melanoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D009362:Neoplasm Metastasis / Q000473:pathology / Q000532:radiotherapy; D009367:Neoplasm Staging; D011379:Prognosis; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D016019:Survival Analysis; D013997:Time Factors