title: Functional infrared imaging of paroxysmal ischemic events in patients with Raynaud's phenomenon.
abstract: The use of thermal infrared (IR) imaging together with the study of the thermal recovery from a controlled cold challenge has been proposed in the diagnosis and follow-up of therapeutic response of Raynaud's Phenomenon (RP) and Systemic Sclerosis (SSc). The controlled cold challenge test usually performed during IR investigations may induce a RP in patients with the latter condition. In our Institution we routinely perform capillaroscopy and thermal IR to follow-up SSc patients. In this paper, we describe the thermal recovery patterns shown by two SSc patients (a 40 year-old male with diffuse variant of SSc and a 71 year-old female with a limited variant of SSc) who presented ischemic and paroxysmal RP attack while recovering from the routine controlled cold challenge test. During RP attack, the cutaneous temperature of some fingers continued to decrease for some minutes even after the cessation of the cold stress. To the best of our knowledge, to date, no literature report has documented the thermal behaviour of SSc patients' fingers which occasionally present ischemic and paroxysmal response. Triggering of ischemic RP attack appears to not rely only on morphological and structural finger impairment, but also upon other aspects, like the emotional attitude of the subject and the possible discomfort experienced with the proceeding of the functional cold stress test.
authors.forename: G
authors.initials: G
authors.lastname: Grossi
authors.forename: A
authors.initials: A
authors.lastname: Mariotti
authors.forename: L
authors.initials: L
authors.lastname: Di Donato
authors.forename: P
authors.initials: P
authors.lastname: Amerio
authors.forename: A
authors.initials: A
authors.lastname: Tulli
authors.forename: G L
authors.initials: GL
authors.lastname: Romani
authors.forename: A
authors.initials: A
authors.lastname: Merla
mesh_terms: D000328:Adult; D000368:Aged; D003080:Cold Temperature; D005260:Female; D005385:Fingers / Q000098:blood supply; D006801:Humans; D007259:Infrared Rays; D007511:Ischemia / Q000175:diagnosis*; D008297:Male; D011928:Raynaud Disease / Q000503:physiopathology*; D012595:Scleroderma, Systemic / Q000503:physiopathology*; D012881:Skin Temperature; D014661:Vasoconstriction