title: Are both psychological and physical dimensions in health-related quality of life associated with mortality in hemodialysis patients: a 7-year Taiwan cohort study.
abstract: BACKGROUND
  Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort in Taiwan.
  
  
  METHODS
  A total of 888 stable hemodialysis patients were included. Patients completed two questionnaires: the 36-item Short Form Health Survey Questionnaire (SF-36, Taiwan Standard Version 1.0) and the Beck Depression Inventory (BDI, Chinese Version). Mortality outcomes were recorded for a seven-year follow-up period.
  
  
  RESULTS
  There were 303 deaths recorded. BDI scores were inversely related to all health-related quality of life (HRQoL) domains (p < 0.001). In the Cox-proportional hazard model, only poor physical dimension of HRQoL was independently associated with higher mortality.
  
  
  CONCLUSIONS
  Poor physical dimension in HRQoL is a strong predictor of mortality among hemodialysis patients in Taiwan. Psychological depression is closely correlated with poor HRQoL but does not predict mortality.
authors.affiliation: Department of Internal Medicine, Far Eastern Memorial Hospital, Taiwan, ROC.
authors.forename: Yu-Sen
authors.initials: YS
authors.lastname: Peng
authors.forename: Chih-Kang
authors.initials: CK
authors.lastname: Chiang
authors.forename: Kung-Yu
authors.initials: KY
authors.lastname: Hung
authors.forename: Chung-Hsin
authors.initials: CH
authors.lastname: Chang
authors.forename: Chien-Yu
authors.initials: CY
authors.lastname: Lin
authors.forename: Chwei-Shiun
authors.initials: CS
authors.lastname: Yang
authors.forename: Tzen-Wen
authors.initials: TW
authors.lastname: Chen
authors.forename: Ching-Chih
authors.initials: CC
authors.lastname: Hsia
authors.forename: Da-Lung
authors.initials: DL
authors.lastname: Chen
authors.forename: Wen-Ding
authors.initials: WD
authors.lastname: Hsu
authors.forename: Chao-Fu
authors.initials: CF
authors.lastname: Chang
authors.forename: Kwan-Dun
authors.initials: KD
authors.lastname: Wu
authors.forename: Ru-Ping
authors.initials: RP
authors.lastname: Lin
authors.forename: Tun-Jun
authors.initials: TJ
authors.lastname: Tsai
authors.forename: Wang-Yu
authors.initials: WY
authors.lastname: Chen
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003863:Depression / Q000209:etiology* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010809:Physical Fitness; D011237:Predictive Value of Tests; D011788:Quality of Life / Q000523:psychology; D006435:Renal Dialysis / Q000401:mortality* / Q000523:psychology; D012189:Retrospective Studies; D011795:Surveys and Questionnaires