title: Common-Path Optical Coherence Tomography for Biomedical Imaging and Sensing.
abstract: This paper describes a development of a fiber optic common-path optical coherence tomography (OCT) based imaging and guided system that possess ability to reliably identify optically transparent targets that are on the micron scale; ability to maintain a precise and safe position from the target; ability to provide spectroscopic imaging; ability to imaging biological target in 3-D. The system is based on a high resolution fiber optic Common-Path OCT (CP-OCT) that can be integrated into various mini-probes and tools. The system is capable of obtaining >70K A-scan per second with a resolution better than 3 μm. We have demonstrated that the system is capable of one-dimensional real-time depth tracking, tool motion limiting and motion compensation, oxygen-saturation level imaging, and high resolution 3-D images for various biomedical applications.
authors.affiliation: Department of Electrical and Computer Engineering, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA.
authors.forename: Jin U
authors.initials: JU
authors.lastname: Kang
authors.forename: Jae-Ho
authors.initials: JH
authors.lastname: Han
authors.forename: Xuan
authors.initials: X
authors.lastname: Liu
authors.forename: Kang
authors.initials: K
authors.lastname: Zhang