Singlet oxygen initiated cascade transformation of a simple difuran into the key ABC-ring motif of the pectenotoxins.
The key ABC-ring motif of the pectenotoxins has been synthesized, starting from a simple and readily accessible difuran precursor, using a complex singlet oxygen-mediated cascade reaction sequence.
Vassilikogiannakis
Georgios
G
Department of Chemistry, University of Crete, 71003 Iraklion, Crete, Greece. vasil@chemistry.uoc.gr
Alexopoulou
Ioanna
I
Tofi
Maria
M
Montagnon
Tamsyn
T
D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D026082:Singlet Oxygen / Q000737:chemistry*; D013237:Stereoisomerism; D000095702:Polyether Toxins
D005663:Furans; D007783:Lactones; D018942:Macrolides; D011714:Pyrans; D026082:Singlet Oxygen; C556578:pectenotoxin 11; D000095702:Polyether Toxins; C550350:pectenotoxin 9; C471227:pectenotoxin-8; C098380:pectenotoxin 2