National Heart, Lung, and Blood Institute working group on emergency department management of acute heart failure: research challenges and opportunities.
This paper details the substance and recommendations arising from a meeting convened by the National Heart, Lung, and Blood Institute in August 2009, to assess the challenges and opportunities of emergency department management of acute heart failure syndrome (AHFS). The assembled faculty represented a large cross section of medical professionals spanning the medical management continuum of patients presenting with acute heart failure and included heart failure cardiologists, emergency physicians, laboratory medicine specialists, nurses, and bench scientists. Their recommendations include proposals regarding the design and conduct of emergency department-based clinical trials, suggestions regarding the development of improved methods for early detection and monitoring of AHFS, and potential needs for expanding translational and applied AHFS focused research and biotechnology. We anticipate that this review will serve as a starting point for future investigations across the spectrum of funding sources.
Peacock
W Frank
WF
The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA. Peacocw@ccf.org
Braunwald
Eugene
E
Abraham
William
W
Albert
Nancy
N
Burnett
John
J
Christenson
Rob
R
Collins
Sean
S
Diercks
Deborah
D
Fonarow
Greg
G
Hollander
Judd
J
Kellerman
Art
A
Gheorghiade
Mihai
M
Kirk
Doug
D
Levy
Phil
P
Maisel
Alan
A
Massie
Barry M
BM
O'Connor
Christopher
C
Pang
Peter
P
Shah
Monica
M
Sopko
George
G
Stevenson
Lynne
L
Storrow
Alan
A
Teerlink
John
J
D000208:Acute Disease; D002309:Cardiology / Q000191:economics / Q000379:methods* / Q000458:organization & administration; D002986:Clinical Trials as Topic; D004635:Emergency Medicine / Q000191:economics / Q000379:methods* / Q000458:organization & administration; D005544:Forecasting; D006333:Heart Failure / Q000191:economics / Q000628:therapy*; D006439:Hemodynamics; D006801:Humans; D054555:National Heart, Lung, and Blood Institute (U.S.); D009316:National Institutes of Health (U.S.); D017063:Outcome Assessment, Health Care; D012107:Research Design / Q000639:trends; D014481:United States