title: Sodium bicarbonate solution as an anti-erosive agent against simulated endogenous erosion.
abstract: This study investigated whether sodium bicarbonate solution, applied on enamel previously exposed to a simulated intrinsic acid, can control dental erosion. Volunteers wore palatal devices containing enamel slabs, which were exposed twice daily extra-orally to hydrochloric acid (0.01 M, pH 2) for 2 min. Immediately afterwards, the palatal devices were re-inserted in the mouth and volunteers rinsed their oral cavity with a sodium bicarbonate solution or deionized water for 60 s. After the washout period, the palatal devices were refilled with a new set of specimens and participants were crossed over to receive the alternate rinse solution. The surface loss and surface microhardness (SMH) of specimens were assessed. The surface loss of eroded enamel rinsed with a sodium bicarbonate solution was significantly lower than the surface loss of eroded enamel rinsed with deionized water. There were no differences between treatments with sodium bicarbonate and deionized water for SMH measurements. Regardless of the solution used as an oral rinse, eroded enamel showed lower SMH than uneroded specimens. Rinsing with a sodium bicarbonate solution after simulated endogenous erosive challenge controlled enamel surface loss but did not alter the microhardness.
authors.affiliation: School of Dentistry, University of Ribeirão Preto, Ribeirão Preto, SP, Brazil. danimessias@gmail.com
authors.forename: Danielle C F
authors.initials: DC
authors.lastname: Messias
authors.forename: Cecilia P
authors.initials: CP
authors.lastname: Turssi
authors.forename: Anderson T
authors.initials: AT
authors.lastname: Hara
authors.forename: Mônica C
authors.initials: MC
authors.lastname: Serra
mesh_terms: D000328:Adult; D000818:Animals; D002021:Buffers; D002417:Cattle; D018592:Cross-Over Studies; D003743:Dental Enamel / Q000187:drug effects / Q000473:pathology; D005744:Gastric Acid; D006244:Hardness; D006801:Humans; D006851:Hydrochloric Acid / Q000009:adverse effects*; D012463:Saliva / Q000502:physiology; D017693:Sodium Bicarbonate / Q000627:therapeutic use*; D013997:Time Factors; D014077:Tooth Erosion / Q000139:chemically induced / Q000517:prevention & control*; D014867:Water
chemical_list: D002021:Buffers; D014867:Water; D017693:Sodium Bicarbonate; D006851:Hydrochloric Acid