title: International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO).
abstract: Reviews find a likely adverse effect of air pollution on perinatal outcomes, but variation of findings hinders the ability to incorporate the research into policy. The International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO) was formed to better understand relationships between air pollution and adverse birth outcomes through standardized parallel analyses in datasets from different countries. A planning group with 10 members from 6 countries was formed to coordinate the project. Collaboration participants have datasets with air pollution values and birth outcomes. Eighteen research groups with data for approximately 20 locations in Asia, Australia, Europe, North America, and South America are participating, with most participating in an initial pilot study. Datasets generally cover the 1990s. Number of births is generally in the hundreds of thousands, but ranges from around 1,000 to about one million. Almost all participants have some measure of particulate matter, and most have ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. Strong enthusiasm for participating and a geographically-diverse range of participants should lead to understanding uncertainties about the role of air pollution in perinatal outcomes and provide decision-makers with better tools to account for pregnancy outcomes in air pollution policies.
authors.affiliation: Program on Reproductive Health and Environment, University of California-San Francisco, Oakland, CA 94612, USA. woodrufft@obgyn.ucsf.edu
authors.forename: Tracey J
authors.initials: TJ
authors.lastname: Woodruff
authors.forename: Jennifer D
authors.initials: JD
authors.lastname: Parker
authors.forename: Kate
authors.initials: K
authors.lastname: Adams
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Bell
authors.forename: Ulrike
authors.initials: U
authors.lastname: Gehring
authors.forename: Svetlana
authors.initials: S
authors.lastname: Glinianaia
authors.forename: Eun-Hee
authors.initials: EH
authors.lastname: Ha
authors.forename: Bin
authors.initials: B
authors.lastname: Jalaludin
authors.forename: Rémy
authors.initials: R
authors.lastname: Slama
mesh_terms: D000397:Air Pollution / Q000009:adverse effects* / Q000706:statistics & numerical data; D002248:Carbon Monoxide / Q000633:toxicity; D005260:Female; D014943:Global Health; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007391:International Cooperation; D010126:Ozone / Q000633:toxicity; D052638:Particulate Matter / Q000009:adverse effects*; D010865:Pilot Projects; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology*; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D052638:Particulate Matter; D010126:Ozone; D002248:Carbon Monoxide