Albizosides D and E, two new cytotoxic triterpene saponins from Albizia chinensis.
Two oleanane-type triterpene saponins, named albizosides D and E (1 and 2), together with a known compound, Julibroside J(8) (3), were isolated from the stem bark of Albizia chinensis. The structures of compounds 1 and 2 were established by 1D, 2D NMR experiments, and chemical methods, and they showed moderate cytotoxic activity against a small panel of human tumor cell lines.
Liu
Rui
R
Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Ma
Shuang-Gang
SG
Liu
Yu-Xi
YX
Yu
Shi-Shan
SS
Chen
Xiao-Guang
XG
Zhang
Jian-Jun
JJ
D031289:Albizzia / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
D000970:Antineoplastic Agents; D012503:Saponins; D014315:Triterpenes