title: Nuclear Pore Protein p62 Autoantibodies in Systemic Lupus Erythematosus.
abstract: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease which is classically characterised by a variety of autoantibodies to deoxyribonucleic acid (DNA), ribonucleic acid (RNA), other nuclear and cytoplasmic antigens. Recently several novel autoantibodies against a variety of specific nuclear pore proteins have been described, including the nucleoporin p62. In this paper we evaluate anti-nucleoporin p62 antibodies by western blot analysis in 25 systemic lupus erythematosus patients. Six patients showed antibodies directed against nucleoporin p62. Our data indicate that p62 antibodies could be a useful additional marker in SLE.
authors.affiliation: Queen's Cancer Centre, Hull, UK.
authors.forename: Doris M
authors.initials: DM
authors.lastname: Kraemer
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Tony