title: Intragastric balloon followed by diet vs intragastric balloon followed by another balloon: a prospective study on 100 patients.
abstract: Aim of this study is to compare the efficacy of BioEnterics Intragastric Balloon (BIB®) followed by diet with BIB followed by another BIB. A prospective study was designed: a homogeneous group of 100 obese patients (age range 25-35, BMI range 40.0-44.9, M/F ratio 1/4) was allocated into two groups according to procedure: BIB (6 months) followed by diet therapy (7 months; group A = 50 pts), BIB positioning followed by another BIB after 1 month (group B = 50 pts). Baseline demographics were similar in both groups (Group A 10M/40F; mean age 31.4 ± 2.6; range 25-35; mean weight 106.3 ± 12.5 Kg; range 88-150; mean BMI 42.6±2.7 Kg/m(2); range 40.2-43.8; Group B 10M/40F; mean age 32.1 ± 2.1; range 25-35; mean weight 107.1 ± 11.9 Kg; range 90-150; mean BMI 42.9 ± 2.3; range 40.2-43.9). In both groups, weight loss parameters (Kg, BMI, and % EBL) were considered. Statistics were by Fisher's exact test (p < 0.05 was considered significant). At the time of 1st BIB removal, weight loss parameters in both groups were not significantly different: Group A: mean weight was 83.7±19.1 (range 52-151); mean BMI 34.2 ± 3.9 (range 32.4-43.8); and mean %EBL 43.5 ± 21.1 (range 0-68). Group B: mean weight was 84.9 ± 18.3 (range 50-148); mean BMI 34.8 ± 3.3 (range 32.4-43.8); and mean % EBL 45.2 ± 22.5% (range 0-68). At the study end, weight loss parameters were significantly lower in patients who underwent consecutive BIB (p < 0.05): mean BMI was 30.9 ± 7.2 Kg/m(2) (range 24-40), and 35.9 ± 9.7 Kg/m(2) (range 34-42); mean % EBL was 51.9 ± 24.6% (range 0-100) and 25.1 ± 26.2% (range 0-100) in group B and A, respectively. As compared with diet, a second intragastric balloon can be positioned without difficulties, achieving good results with continuous weight loss.
authors.affiliation: Laparoscopic Surgical Department, Medical School, Sapienza University, Rome, Italy. michele.lorenzo@gmail.com
authors.forename: Alfredo
authors.initials: A
authors.lastname: Genco
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Cipriano
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bacci
authors.forename: Roberta
authors.initials: R
authors.lastname: Maselli
authors.forename: Emanuela
authors.initials: E
authors.lastname: Paone
authors.forename: Michele
authors.initials: M
authors.lastname: Lorenzo
authors.forename: Nicola
authors.initials: N
authors.lastname: Basso
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D004038:Diet, Reducing; D005260:Female; D015905:Gastric Balloon; D006801:Humans; D008297:Male; D009765:Obesity / Q000601:surgery / Q000628:therapy*; D011446:Prospective Studies; D012086:Reoperation