title: Colonic angiolymphoid hyperplasia with eosinophilia masquerading as malignancy: a case report and review of the literature.
abstract: Angiolymphoid hyperplasia with eosinophilia (AHE) of the colon is a rare entity. Since 1997, to our knowledge only 2 similar cases have been documented in the literature. Here, we report a third case that presented as a transverse colonic mass mimicking cancer both clinically and radiologically. Microscopically classic morphologic criteria of this entity were observed, which consisted of both a vascular proliferation and an inflammatory component rich in eosinophils without any malignant features. Whether AHE is a reactive process or a neoplastic process (either a benign vascular neoplasm or a T-cell lymphoproliferative disorder) is still under debate. However, it is important to recognize this entity as a cause of colonic mass to avoid a misdiagnosis of malignancy.
authors.affiliation: Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612-9497, USA.
authors.forename: Marilyn M
authors.initials: MM
authors.lastname: Bui
authors.forename: Nicole L
authors.initials: NL
authors.lastname: Draper
authors.forename: Sophie
authors.initials: S
authors.lastname: Dessureault
authors.forename: Nelly A
authors.initials: NA
authors.lastname: Nasir
authors.forename: Harry
authors.initials: H
authors.lastname: Cooper
authors.forename: Aejaz
authors.initials: A
authors.lastname: Nasir
authors.forename: Domenico
authors.initials: D
authors.lastname: Coppola
mesh_terms: D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology*; D003108:Colonic Diseases / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications; D006391:Hemangioma / Q000150:complications; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications