title: Antilip®: treatment of subjects with high total cholesterol tolerability and efficacy in a short-term registry study.
abstract: OBJECTIVE
  The aim of the paper was to describe a new formula (Antilip®) consisting of very low dosages of polyglucosamine, phytosterols and Monascus purpureus. It was given to subjects affected by high cholesterol levels.
  
  
  METHODS
  The formula was used in combination with mild physical exercise (8 MET/h/week) and mild diet (reduction of cholesterol intake through foods containing <80 mg/100 g). The product combination was tested in an 8-week registry study, comparing those subjects to 33 subjects with no Antilip® treatment but following the same mild exercise training and diet.
  
  
  RESULTS
  Results showed that Antilip® was effective in significantly reducing the total cholesterol levels from 268+/-23.2 to 201+/-11.4, whereas in the control group the reduction was almost absent (from 273+/-27 to 267+/-28).
  
  
  CONCLUSIONS
  Data shows that Antilip® is a safe and effective treatment for hypercholesterolemia.
authors.affiliation: Irvine3 Labs, Department Biomedical Sciences, Chieti-Pescara University, Pescara, Italy.
authors.forename: M R
authors.initials: MR
authors.lastname: Cesarone
authors.forename: A
authors.initials: A
authors.lastname: Ledda
authors.forename: G
authors.initials: G
authors.lastname: Belcaro
authors.forename: A
authors.initials: A
authors.lastname: Ricci
authors.forename: S
authors.initials: S
authors.lastname: Stuard
authors.forename: L
authors.initials: L
authors.lastname: Pellegrini
authors.forename: E
authors.initials: E
authors.lastname: Ippolito
authors.forename: U
authors.initials: U
authors.lastname: Cornelli
mesh_terms: D000117:Acetylglucosamine / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000378:metabolism*; D004032:Diet; D015444:Exercise; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D032741:Monascus / Q000378:metabolism*; D010840:Phytosterols / Q000627:therapeutic use*; D010936:Plant Extracts / Q000627:therapeutic use; D012042:Registries; D016896:Treatment Outcome
chemical_list: D010840:Phytosterols; D010936:Plant Extracts; C113831:poly-N-acetyl glucosamine; D002784:Cholesterol; D000117:Acetylglucosamine