title: Medicine. Sickle cell disease at 100 years.
authors.affiliation: Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA 02115, USA. stuart_orkin@dfci.harvard.edu
authors.forename: Stuart H
authors.initials: SH
authors.lastname: Orkin
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Higgs
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000235:genetics / Q000628:therapy; D002352:Carrier Proteins / Q000235:genetics; D005319:Fetal Hemoglobin / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics*; D019204:GTP-Binding Proteins / Q000235:genetics; D005786:Gene Expression Regulation; D020570:Genes, myb; D006451:Hemoglobin, Sickle / Q000737:chemistry / Q000235:genetics; D006801:Humans; D005810:Multigene Family; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics; D012097:Repressor Proteins; D055544:beta-Globins / Q000235:genetics; D055545:gamma-Globins / Q000235:genetics
chemical_list: C486563:BCL11A protein, human; D002352:Carrier Proteins; D006451:Hemoglobin, Sickle; D009687:Nuclear Proteins; D012097:Repressor Proteins; D055544:beta-Globins; D055545:gamma-Globins; D005319:Fetal Hemoglobin; D019204:GTP-Binding Proteins