title: Ascending aorta and aortic root reoperations: are outcomes worse than first time surgery?
abstract: BACKGROUND
  The aim of this study was to analyze surgery and survival data in the midterm after aortic root and (or) ascending aorta reoperations and compare these results with those obtained after first time surgery.
  
  
  METHODS
  Over a 6-year period, 365 patients underwent an aortic root and (or) ascending aorta surgery procedure at our center. Mean patient age was 63.1 + or - 25.5 years; 27.1% were women. Fifty-eight patients had had prior ascending aorta and (or) aortic valve surgery (group I) and the remaining 307 patients were assigned to an initial surgery group (II). The reoperative procedures were Bentall in 45 (77.6%), ascending aorta and valve replacement in 8 (13.8%), and ascending aorta replacement in 5 (8.6%).
  
  
  RESULTS
  The reoperation group showed a worse preoperative risk profile indicated by a higher logistic European system for cardiac operative risk evaluation: group I (26.9) versus group II (9.9) (p < 0.0001). Hospital mortality was 7 of 58 (12.1%) in group I and 21 of 207 (6.8%) in group II (p = 0.18; relative risk 1.9 [0.8 to 4.6]). After adjusting for the different variables, reoperation could not be identified as an independent predictor of postoperative morbidity. Survival rates (including in-hospital mortality) were lower in group I at one year (77.9 + or - 1.11% vs 91.9 + or - 0.3%) and at 3 years (75.3 + or - 0.11% vs 88.9 + or - 0.03% [log-rank p = 0.005]). In the multivariate analysis, reoperation (p = 0.01; hazard ratio 2.6 [1.2 to 5.3]) was a determining factor for survival once corrected for variables predicting mortality during follow-up.
  
  
  CONCLUSIONS
  Reoperations on the ascending aorta and aortic root showed acceptable morbidity and mortality. Their midterm survival was lower than for patients not requiring a repeat operation.
authors.affiliation: Unit of Cardiac Surgery, Hospital Clínico San Carlos, Madrid 28040, Spain. jsilva8252@yahoo.es
authors.forename: Jacobo
authors.initials: J
authors.lastname: Silva
authors.forename: Luis C
authors.initials: LC
authors.lastname: Maroto
authors.forename: Manuel
authors.initials: M
authors.lastname: Carnero
authors.forename: Isidre
authors.initials: I
authors.lastname: Vilacosta
authors.forename: Javier
authors.initials: J
authors.lastname: Cobiella
authors.forename: Enrique
authors.initials: E
authors.lastname: Villagrán
authors.forename: José E
authors.initials: JE
authors.lastname: Rodríguez
mesh_terms: D001011:Aorta / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome