title: Morbidity and mortality rates associated with serial bleeding from the superficial temporal vein in mice.
abstract: The authors reviewed 3 years' worth of records of superficial temporal vein phlebotomies that had been carried out in Balb/c mice. Mice that had undergone the phlebotomies had a mortality rate of approximately 1% (4 deaths per 490 procedures). Although the mice were being used in a drug study, necropsy and blood assay results suggest that the four deaths were caused by failure to stop the bleeding after the phlebotomies. The authors offer suggestions for improving morbidity and mortality associated with temporal vein phlebotomy.
authors.affiliation: Department of Molecular and Comparative Pathobiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Nadine
authors.initials: N
authors.lastname: Forbes
authors.forename: Cory
authors.initials: C
authors.lastname: Brayton
authors.forename: Susan
authors.initials: S
authors.lastname: Grindle
authors.forename: Starane
authors.initials: S
authors.lastname: Shepherd
authors.forename: Starain
authors.initials: S
authors.lastname: Shepherd
authors.forename: Betty
authors.initials: B
authors.lastname: Tyler
authors.forename: Michael
authors.initials: M
authors.lastname: Guarnieri
mesh_terms: D000818:Animals; D005145:Face / Q000098:blood supply*; D005260:Female; D006470:Hemorrhage / Q000401:mortality*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D018962:Phlebotomy / Q000401:mortality* / Q000662:veterinary*; D015996:Survival Rate; D014680:Veins / Q000033:anatomy & histology / Q000502:physiology*