title: Concise synthesis of Cannabisin G.
abstract: Cannabisin G (1), a naturally occurring lignanamide, was synthesized in 45% overall yield starting from 3-tert-butyl ethyl ferulate (6). An oxidative coupling by potassium ferricyanide in an alkaline media serves as the key step to construct the biphenylbutadiene skeleton of 1 with high regioselectivity.
authors.affiliation: Department of Chemistry, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
authors.forename: Dawei
authors.initials: D
authors.lastname: Li
authors.forename: Wenling
authors.initials: W
authors.lastname: Li
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Zhaoqi
authors.initials: Z
authors.lastname: Yang
authors.forename: Zijie
authors.initials: Z
authors.lastname: Hou
mesh_terms: D005295:Ferrocyanides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D010636:Phenols / Q000138:chemical synthesis*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D005295:Ferrocyanides; D010636:Phenols; C093865:cannabisin G; C031835:potassium ferrocyanide