Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study.
OBJECTIVE
To report the prevalence and risk factors associated with primary open-angle glaucoma (POAG) in the Kandy district of central Sri Lanka.


METHODS
A cross-sectional, population-based ophthalmic survey of the inhabitants >or= 40 years of age from villages in the Kandy District, Sri Lanka was conducted. Selection was randomized using a cluster sampling process; 1721 eligible participants were identified, 1375 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1244 participants. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Primary open-angle glaucoma was classified into three levels according to diagnostic evidence.


RESULTS
The overall prevalence of POAG was 2.3% (95% CI 1.5-3.2). In the univariate analyses, increasing age (P = 0.001), intraocular pressure (IOP) (P < 0.001), myopia (P < 0.001) and axial length (P = 0.003) were significantly associated with POAG. In the multivariate analysis, age (P = 0.001), mean IOP (P < 0.001) and mean axial length (P = 0.008) were significant risk factors of POAG.


CONCLUSIONS
The prevalence of POAG in the population aged >or=40 years in central Sri Lanka was 2.3%. POAG in this population was independently associated with increasing age, IOP and axial length.
Sia
David I T
DI
University of Adelaide, Adelaide, Australia. daviditsia@gmail.com
Edussuriya
Kapila
K
Sennanayake
Saman
S
Senaratne
Tissa
T
Selva
Dinesh
D
Casson
Robert J
RJ
D000328:Adult; D017677:Age Distribution; D000368:Aged; D016000:Cluster Analysis; D003430:Cross-Sectional Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D013188:Sri Lanka / Q000453:epidemiology