Candidal arthritis in revision knee arthroplasty successfully treated with sequential parenteral-oral fluconazole and amphotericin B-loaded cement spacer.
We present a case of a patient with preoperative cutaneous candidiasis, who developed candidal infection during stage revision knee arthroplasty. The patient received intravenous fluconazole for 6 weeks and resection arthroplasty with an amphotericin B-loaded cement spacer and continuous oral fluconazole therapy for 9 weeks. Revision surgery was successful.
Wu
Meng-Huang
MH
Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Hsu
Kuo-Yao
KY
D000284:Administration, Oral; D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage*; D001170:Arthritis, Infectious / Q000188:drug therapy*; D019645:Arthroplasty, Replacement, Knee; D001843:Bone Cements; D002177:Candidiasis / Q000188:drug therapy*; D015725:Fluconazole / Q000008:administration & dosage*; D006801:Humans; D007263:Infusions, Parenteral; D007719:Knee Joint / Q000000981:diagnostic imaging; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D011859:Radiography; D012086:Reoperation
D000935:Antifungal Agents; D001843:Bone Cements; D000666:Amphotericin B; D015725:Fluconazole