title: [Growth differentiation factor 15--a new marker in heart diseases].
abstract: Growth differentiation factor-15 (GDF-15) is a cytokine with cardioprotective properties, which inhibits hypertrophy, cardiac remodeling and apoptosis. Participates in the life and cell death. The concentration of GDF-15 rapidly increases under the influence of ischemia-reperfusion damage to heart muscle, oxidative stress, inflammatory cytokines and pressure overload. In patients with acute coronary syndromes, heart failure and pulmonary embolism provides independent prognostic information, both short-and long-term. It is potentially a new marker of risk stratification in patients with heart disease and therapeutic decision making.
authors.affiliation: 10 Wojskowy Szpital Kliniczny z Poliklinik. w Bydgoszczy, Klinika Kardiologii, Oddział Kardiologii Inwazyjnej.
authors.forename: Maciej
authors.initials: M
authors.lastname: Olechnicki
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Kasprzak
authors.forename: Aleksander
authors.initials: A
authors.lastname: Goch
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D055436:Growth Differentiation Factor 15 / Q000378:metabolism*; D006331:Heart Diseases / Q000175:diagnosis / Q000378:metabolism*; D006801:Humans; D018570:Risk Assessment / Q000379:methods
chemical_list: D015415:Biomarkers; D055436:Growth Differentiation Factor 15