Pregnancy achieved by transfer of a single blastocyst selected by time-lapse monitoring.
Appropriate selection of a single blastocyst for transfer decreases the risk of multiple gestations. By using a compact time-lapse microscope system placed inside a regular incubator, combined with a microwell embryo culture dish, the development of all the embryos from a patient was continuously monitored by obtaining images at 10 min intervals. The embryos were not moved during the time-lapse observation. The system was switched off completely between image acquisitions in order to avoid exposure to electromagnetic radiation. The analysis of time-lapse records was used to choose a single blastocyst for transfer, which resulted in a singleton pregnancy and birth of a healthy boy on term.
Pribenszky
Csaba
C
Department of Animal Breeding and Genetics, Faculty of Veterinary Science, Szent István University, István u. 2., Budapest 1078, Hungary.
Mátyás
Szabolcs
S
Kovács
Péter
P
Losonczi
Eszter
E
Zádori
János
J
Vajta
Gábor
G
D000328:Adult; D001755:Blastocyst; D046149:Embryo Culture Techniques / Q000379:methods; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D008853:Microscopy / Q000379:methods; D011247:Pregnancy; D056826:Single Embryo Transfer / Q000379:methods*; D059008:Time-Lapse Imaging / Q000379:methods