title: Retinopathy of prematurity in 7 neonatal units in Rio de Janeiro: screening criteria and workload implications.
abstract: OBJECTIVE
  The goals were to determine optimal screening criteria for retinopathy of prematurity (ROP) in 7 neonatal units in Rio de Janeiro, Brazil, and to explore the workload implications of applying different criteria.
  
  
  METHODS
  Infants with birth weights of < or = 2000 g or gestational age of <37 weeks were examined by 3 ophthalmologists in 7 of the largest units in Rio de Janeiro, during a 34-month period. ROP was classified by using the international classification, and laser treatment was given to infants developing type 1 ROP.
  
  
  RESULTS
  A total of 3437 (87%) of 3953 eligible infants were examined, of whom 124 (3.6% [range: 2.1%-7.8%]) were treated. Eleven infants were treated for aggressive posterior ROP. Appropriate screening criteria for the 2 NICUs with high survival rates (ie, > or =80% among infants with birth weights of <1500 g) would be < or =1500 g or <32 weeks. For NICUs with low survival rates (ie, <80%), appropriate criteria would be < or =1500 g or < or =35 weeks. UK, US, and previous Brazilian criteria would all miss infants needing treatment.
  
  
  CONCLUSIONS
  ROP programs in Brazil should use the wider criteria of < or =1500 g or < or =35 weeks until further evidence-based criteria become available, although this would mean a slight increase in workload across the city, compared with use of the narrower criteria in the better units. Whether survival rates can be used as a proxy to indicate screening criteria requires further investigation.
authors.affiliation: Department of Neonatology, Fernandes Figueira Institute, Rio de Janeiro, Brazil. andreazin@iff.fiocruz.br
authors.forename: Andrea A
authors.initials: AA
authors.lastname: Zin
authors.forename: Maria Elisabeth Lopes
authors.initials: ME
authors.lastname: Moreira
authors.forename: Catey
authors.initials: C
authors.lastname: Bunce
authors.forename: Brian A
authors.initials: BA
authors.lastname: Darlow
authors.forename: Clare E
authors.initials: CE
authors.lastname: Gilbert
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002391:Catchment Area, Health; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D015997:Neonatal Screening / Q000379:methods*; D015995:Prevalence; D012016:Reference Values; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000453:epidemiology*; D012720:Severity of Illness Index; D016526:Workload / Q000706:statistics & numerical data*