On chirp stimuli and neural synchrony in the suprathreshold auditory brainstem response.
The chirp-evoked ABR has been regarded as a more synchronous response than the click-evoked ABR, referring to the belief that the chirp stimulates lower-, mid-, and higher-frequency regions of the cochlea simultaneously. In this study a variety of tools were used to analyze the synchronicity of ABRs evoked by chirp- and click-stimuli at 40 dB HL in 32 normal hearing subjects aged 18 to 55 years (mean=24.8 years, SD=7.1 years). Compared to the click-evoked ABRs, the chirp-evoked ABRs showed larger wave V amplitudes, but an absence of earlier waves in the grand averages, larger wave V latency variance, smaller FFT magnitudes at the higher component frequencies, and larger phase variance at the higher component frequencies. These results strongly suggest that the chirp-evoked ABRs exhibited less synchrony than the click-evoked ABRs in this study. It is proposed that the temporal compensation offered by chirp stimuli is sufficient to increase neural recruitment (as measured by wave V amplitude), but that destructive phase interactions still exist along the cochlea partition, particularly in the low frequency portions of the cochlea where more latency jitter is expected. The clinical implications of these findings are discussed.
Petoe
Matthew A
MA
School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Queensland 4072, Australia.
Bradley
Andrew P
AP
Wilson
Wayne J
WJ
D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D001306:Auditory Pathways / Q000502:physiology*; D001309:Auditory Threshold; D001933:Brain Stem / Q000502:physiology*; D003051:Cochlea / Q000502:physiology; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time; D013018:Sound Spectrography; D013997:Time Factors; D055815:Young Adult