The Microbiology of Community-acquired Peritonitis in Children.
BACKGROUND
microbiologic data are lacking regarding pediatric community-acquired peritonitis (CAP).


METHODS
we conducted a 2-year retrospective single center study. Consecutive children undergoing CAP surgery were included. Microbiology and antimicrobial susceptibility of peritoneal isolates were analyzed.


RESULTS
a total of 70 children from 3 months to 14 years of age were included. A total of 123 bacterial isolates were analyzed. Escherichia coli was the predominant aerobic organism (51% of isolates); 54.8% were susceptible to amoxicillin whereas 90.3% were susceptible to amoxicillin-clavulanate. Anaerobes accounted for 29% of isolates, and 94.3% of strains were susceptible to amoxicillin-clavulanate and 68.5% were susceptible to clindamycin. Pseudomonas aeruginosa was present in 6% of isolates and in 10% of children. The presence of E. coli resistant to amoxicillin or to amoxicillin-clavulanate was the only independent risk factor associated with postoperative peritonitis.


CONCLUSIONS
microbiology of pediatric CAP is similar to adult CAP with a predominancy of E. coli and anaerobes. P. aeruginosa in peritoneal samples had no apparent influence on the outcome.
Dumont
Romain
R
CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie-Réanimation, Nantes, France.
Cinotti
Raphaël
R
Lejus
Corinne
C
Caillon
Jocelyne
J
Boutoille
David
D
Roquilly
Antoine
A
Podevin
Guillaume
G
Gras-Le Guen
Christelle
C
Asehnoune
Karim
K
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D010538:Peritonitis / Q000453:epidemiology* / Q000382:microbiology*; D015995:Prevalence; D012189:Retrospective Studies
D000900:Anti-Bacterial Agents