title: Laparoscopic versus open gastrectomy for adenocarcinoma: a prospective comparative analysis.
abstract: OBJECTIVE
  Laparoscopic gastrectomy (LG) is still not a widely accepted option for the treatment of invasive gastric cancer. This study was conducted to evaluate the results of LG for gastric adenocarcinoma in two French surgical departments.
  
  
  METHODS
  Between 2001 and 2007, 51 patients underwent LG for gastric cancer. The results were compared to those of 79 patients who had open gastrectomy (OG) during the same study period.
  
  
  RESULTS
  Mean age was 61 years (31-81) and 66 years (27-88) in the LG group and in the OG group, respectively. The sex ratio was 21 women to 30 men and 25 women for 54 men in the LG group and the OG group, respectively. The mean operative duration was 260 minutes (90-420) and 200 (120-360) the LG group and the OG group, respectively (P=0.11). Estimated operative blood loss was 150 ml (50-870) and 240 (120-955) in the LG group and the OG group, respectively (P=0.07). The mean number of harvested lymph nodes was 19 (8-51) in the LG group and 22 (3-101) in the OG group, respectively (P=0.76). The overall mortality rate was 0% and 2.5% in the LG group and the OG group, respectively (P=0.49). The overall abdominal morbidity rate was 12% and 16.4% in the LG group and the OG group, respectively (P=0.42). The mean duration of hospital stay was 8.0 days (5-23) and 11.5 days (5-31) in the LG group and the OG group, respectively (P=0.023). Survival analysis at 1, 2, and 3 years showed no significant difference between the two groups.
  
  
  CONCLUSIONS
  LG for cancer is feasible and safe in patients with invasive gastric cancer. However, randomized controlled trials are necessary to accurately define the role of laparoscopy in the treatment of gastric cancer.
authors.affiliation: Department of General and Minimally Invasive Surgery, Hospital Center, Poissy, France. chouillard@yahoo.com
authors.forename: E
authors.initials: E
authors.lastname: Chouillard
authors.forename: A A
authors.initials: AA
authors.lastname: Gumbs
authors.forename: F
authors.initials: F
authors.lastname: Meyer
authors.forename: A
authors.initials: A
authors.lastname: Torcivia
authors.forename: N
authors.initials: N
authors.lastname: Helmy
authors.forename: M
authors.initials: M
authors.lastname: Toubal
authors.forename: A
authors.initials: A
authors.lastname: Karaa
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*