title: Pregnancy in a patient with gouty arthritis secondary to pseudo-Bartter syndrome.
abstract: A 32-year-old woman with pseudo-Bartter syndrome secondary to excessive use of laxatives, presented with hypokalemia, metabolic alkalosis, hyperuricemia, and gouty arthritis with tophi. Subsequently the patient became pregnant and displayed recurrent severe gouty flares of multiple joints. Monosodium urate crystals were aspirated from the knee confirming the diagnosis of gout. Previous reports have stated an association between Bartter syndrome and gout, but this is the first case report of a pregnancy with active gouty arthritis combined with pseudo-Bartter syndrome.
authors.affiliation: University of Southern California, Division of Rheumatology, Los Angeles, CA 90033, USA.
authors.forename: Samy
authors.initials: S
authors.lastname: Metyas
authors.forename: Heba
authors.initials: H
authors.lastname: Rouman
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Arkfeld
mesh_terms: D000328:Adult; D015210:Arthritis, Gouty / Q000175:diagnosis* / Q000378:metabolism; D001477:Bartter Syndrome / Q000139:chemically induced / Q000150:complications*; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D054368:Laxatives / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D014527:Uric Acid / Q000378:metabolism
chemical_list: D054368:Laxatives; D014527:Uric Acid