When the first antiepileptic drug fails in a patient with juvenile myoclonic epilepsy.
Juvenile myoclonic epilepsy is one of the most common types of epilepsy seen in an adult epilepsy clinic. Most patients have a good prognosis, particularly when treated with valproate, but a significant minority are more difficult to treat. In this article, we will focus on a management strategy when the initial antiepileptic drug is unsuccessful and outline an approach that translates directly to the clinic.
Nicolson
Andrew
A
The Walton Centre NHS Foundation Trust, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK. andrew.nicolson@thewaltoncentre.nhs.uk
Marson
Anthony G
AG
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002985:Clinical Protocols; D019468:Disease Management; D004351:Drug Resistance / Q000502:physiology*; D006801:Humans; D020190:Myoclonic Epilepsy, Juvenile / Q000188:drug therapy*; D017211:Treatment Failure
D000927:Anticonvulsants