A natural genetic polymorphism affects retroactive interference in Drosophila melanogaster.
As environments change, animals update their internal representations of the external world. New information about the environment is learned and retained whereas outdated information is disregarded or forgotten. Retroactive interference (RI) occurs when the retrieval of previously learned information is less available owing to the acquisition of recently acquired information. Even though RI is thought to be a major cause of forgetting, its functional significance is still under debate. We find that natural allelic variants of the Drosophila melanogaster foraging gene known to affect rover and sitter behaviour differ in RI. More specifically, rovers who were previously shown to experience greater environmental heterogeneity while foraging display RI whereas sitters do not. Rover responses are biased towards more recent learning events. These results provide an ecological context to investigate the function of forgetting via RI and a suitable genetic model organism to address the evolutionary relevance of cognitive tasks.
Reaume
Christopher J
CJ
Department of Biology, University of Toronto at Mississauga, Mississauga, Ontario, Canada, L5L 1C6.
Sokolowski
Marla B
MB
Mery
Frederic
F
D000818:Animals; D005075:Biological Evolution; D003213:Conditioning, Psychological; D017869:Cyclic GMP-Dependent Protein Kinases / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D004777:Environment; D011939:Mental Recall / Q000502:physiology*; D009043:Motor Activity / Q000235:genetics*; D009812:Odorants; D011110:Polymorphism, Genetic
D029721:Drosophila Proteins; D017869:Cyclic GMP-Dependent Protein Kinases; C528566:for protein, Drosophila