Stalling in mitosis and releasing the apoptotic brake.
Kurokawa
Manabu
M
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.
Kornbluth
Sally
S
D064173:Anaphase-Promoting Complex-Cyclosome; D017209:Apoptosis / Q000502:physiology*; D016203:CDC2 Protein Kinase / Q000378:metabolism; D056744:Cyclin B1 / Q000378:metabolism; D008938:Mitosis / Q000502:physiology*; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism*; D043743:Ubiquitin-Protein Ligase Complexes / Q000378:metabolism
D056744:Cyclin B1; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D019253:Proto-Oncogene Proteins c-bcl-2; D043743:Ubiquitin-Protein Ligase Complexes; D064173:Anaphase-Promoting Complex-Cyclosome; D016203:CDC2 Protein Kinase