title: [Diuretics-related complications in elderly patients].
abstract: Diuretics are well studied and evaluated for their beneficial use in geriatric patients. However those drugs are often used without taking care of subjects condition or functional impairment. Known side effects of those substances may be increased by combinations of multiple drugs. Polypharmacy is a strong risk factor for the incidence of adverse drug reactions (ADR). ADRs are frequently found in combination with the use of diuretics. The remodelling of human body in aging process and uncontrolled therapeutic strategies seem to be causal for that finding. This article tries to work out the potential risk of the usage of those drugs in geriatric patients and its clinical relevance by using literature published in PubMed.
authors.affiliation: Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Austria.
authors.forename: Ronald
authors.initials: R
authors.lastname: Otto
authors.affiliation: Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Austria.
authors.forename: Regina E
authors.initials: RE
authors.lastname: Roller
authors.affiliation: Universitätsklinik für Geriatrie, Paracelsus Medizinische Privatuniversität, Salzburg, Austria.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Iglseder
authors.affiliation: Abteilung für Akutgeriatrie/Remobilisation, Landeskrankenhaus Gmunden, Gmunden, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Dovjak
authors.affiliation: Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria.
authors.forename: Monika
authors.initials: M
authors.lastname: Lechleitner
authors.affiliation: Abteilung für Akutgeriatrie, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wien, Austria.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Sommeregger
authors.affiliation: Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria.
authors.forename: Ursula
authors.initials: U
authors.lastname: Benvenuti-Falger
authors.affiliation: Anstaltsapotheke, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wien, Austria.
authors.forename: Birgit
authors.initials: B
authors.lastname: Böhmdorfer
authors.affiliation: Abteilung für Innere Medizin und Akutgeriatrie, Landeskrankenhaus Hochzirl, Zirl, Austria. markus.gosch@tilak.at.
authors.forename: Markus
authors.initials: M
authors.lastname: Gosch
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000369:Aged, 80 and over; D001317:Austria; D003681:Dehydration / Q000139:chemically induced; D004232:Diuretics / Q000009:adverse effects* / Q000627:therapeutic use; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D016330:Frail Elderly; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced
chemical_list: D004232:Diuretics