title: Risk of invasive cervical cancer and cervical intraepithelial neoplasia grade III in central Italy by area of birth.
abstract: OBJECTIVE
  To evaluate cervical cancer incidence among women born in different countries but residing in Italy.
  
  
  METHODS
  Women aged 25-59 from a central Italian population-based cancer registry.
  
  
  METHODS
  Invasive and in situ cervical cancer incidence rates from 2000-2004 were calculated. Standardized incidence rates were based on the European standard population. Places of birth were categorized by nine different areas.
  
  
  RESULTS
  Within the resident population aged 25-59, there were 148 invasive cervical cancers (17.6% in women born outside Italy) and 501 (14.2% in women born outside Italy) cervical intraepithelial neoplasia grade III (CIN III) diagnoses. The incidence of invasive cervical cancer for women born in 'Central & South America and the Caribbean' was 60.5 per 100,000 and in 'Central and Eastern Europe' it was 38.3, statistically significantly higher than for women born in Italy (9.5 per 100,000). The CIN III rate was 35.0 per 100,000 for women born in Italy. The ratio between standardized rates for CIN III and invasive cancers was around 4 for women born in Italy and the 'extended European Union', and around 6 for those born in 'Asia'. It was 1.64 for women born in 'Africa', 1.31 in 'Central & South America and the Caribbean' and 0.69 for those born in 'Eastern Europe'.
  
  
  CONCLUSIONS
  Women who reside in Italy but were born in 'Central & South America and the Caribbean' or in 'Central and Eastern Europe' are at high risk for invasive cervical cancer. These groups are less inclined to participate in screening, and appropriate preventive strategies should be planned accordingly.
authors.affiliation: Clinical and Descriptive Epidemiology Unit, Institute for cancer study and prevention ISPO, Florence, Italy. e.crocetti@ispo.toscana.it
authors.forename: Emanuele
authors.initials: E
authors.lastname: Crocetti
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Manneschi
authors.forename: Carmen Beatriz
authors.initials: CB
authors.lastname: Visioli
authors.forename: Marco
authors.initials: M
authors.lastname: Zappa
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology*