title: Pancreatic involvement detected with (18)F-FDG PET/CT in disseminated sarcoidosis.
abstract: La sarcoidosis is a granulomatous disease of unknown etiology. It may mimic malignancy and may affect multiple organs, with a variable clinical course. Pancreatic involvement is very rare. We present the case of a 78-year-old woman with systemic sarcoidosis whose (18)F-FDG PET/CT scan showed a pancreatic lesion and multiple lymphatic (thoracic and non-thoracic) and visceral lesions. The abnormal (18)F-FDG uptake in the pancreas was limited to the tail. A second (18)F-FDG PET/CT study performed 4 months and 3 weeks after the first PET/CT, following corticosteroid therapy during three and a half months, evidenced partial regression of the disease, with persistent (18)F-FDG pathological uptake in the pancreatic lesion.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, Spain. rbolton@telefonica.net
authors.forename: R C
authors.initials: RC
authors.lastname: Delgado-Bolton
authors.forename: J A
authors.initials: JA
authors.lastname: Arias Navalón
authors.forename: B
authors.initials: B
authors.lastname: Rodríguez Alfonso
authors.forename: A N
authors.initials: AN
authors.lastname: Delgado-Bolton
authors.forename: M J
authors.initials: MJ
authors.lastname: Pérez-Castejón
authors.forename: R
authors.initials: R
authors.lastname: Sánchez-Escribano
authors.forename: M N
authors.initials: MN
authors.lastname: Cabrera Martín
authors.forename: L
authors.initials: L
authors.lastname: Lapeña Gutiérrez
authors.forename: J L
authors.initials: JL
authors.lastname: Carreras Delgado
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18