The mysterious ways of the chemokine CXCL5.
The chemokine receptor CXCR2 binds several chemokines, some of them with functions yet to be defined. In this issue of Immunity, Mei et al. (2010) generated CXCL5-deficient mice and described a prominent role of CXCL5 in the regulation of CXCR2-dependent neutrophil trafficking during pulmonary host defense.
Koltsova
Ekaterina K
EK
Division of Inflammation Biology, La Jolla Institute for Allergy & Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
Ley
Klaus
K