title: Pharmacogenetic vs. concentration-controlled optimization of tacrolimus dosing in renal allograft recipients.
authors.forename: D R J
authors.initials: DR
authors.lastname: Kuypers
mesh_terms: D051544:Cytochrome P-450 CYP3A / Q000235:genetics; D004334:Drug Administration Schedule; D054796:Drug Dosage Calculations; D005838:Genotype; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control*; D006085:Graft Survival / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D016030:Kidney Transplantation / Q000009:adverse effects; D010597:Pharmacogenetics; D010641:Phenotype; D016559:Tacrolimus / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D014184:Transplantation, Homologous; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; C510164:CYP3A5 protein, human; D051544:Cytochrome P-450 CYP3A; D016559:Tacrolimus