title: Spontaneous adsorption of silver nanoparticles on Ti/TiO2 surfaces. Antibacterial effect on Pseudomonas aeruginosa.
abstract: Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation, and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excellent performance as biocides, and thus their integration to titanium surfaces is an attractive strategy to decrease the risk of implant failure. In this work a simple and efficient method is described to modify Ti/TiO(2) surfaces with citrate-capped AgNPs. These nanoparticles spontaneously adsorb on Ti/TiO(2), forming nanometer-sized aggregates consisting of individual AgNPs that homogeneously cover the surface. The modified AgNP-Ti/TiO(2) surface exhibits a good resistance to colonization by Pseudomonas aeruginosa, a model system for biofilm formation.
authors.affiliation: Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET, Casilla de Correo 16, Sucursal 4, (1900) La Plata, Argentina.
authors.forename: C Y
authors.initials: CY
authors.lastname: Flores
authors.forename: C
authors.initials: C
authors.lastname: Diaz
authors.forename: A
authors.initials: A
authors.lastname: Rubert
authors.forename: G A
authors.initials: GA
authors.lastname: Benítez
authors.forename: M S
authors.initials: MS
authors.lastname: Moreno
authors.forename: M A
authors.initials: MA
authors.lastname: Fernández Lorenzo de Mele
authors.forename: R C
authors.initials: RC
authors.lastname: Salvarezza
authors.forename: P L
authors.initials: PL
authors.lastname: Schilardi
authors.forename: C
authors.initials: C
authors.lastname: Vericat
mesh_terms: D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D019343:Citric Acid / Q000737:chemistry* / Q000494:pharmacology; D018625:Microscopy, Atomic Force; D053758:Nanoparticles / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; C009495:titanium dioxide; D019343:Citric Acid; D012834:Silver; D014025:Titanium