Refractive lens exchange with intraocular lens implantation in hyperopic eyes of a patient with Angelman syndrome.
We describe a patient with Angelman syndrome with severe developmental delay who was visually impaired by uncorrected high hyperopia and poor control of accommodation. Refractive lens exchange with intraocular lens implantation was performed in both eyes when the patient was 22 years of age. Satisfactory anatomical and functional outcomes were achieved and maintained during 3 years of follow-up. Refractive lens exchange can be useful in patients with severe neurobehavioral disorders in the presence of high refractive error and poor accommodative control.


BACKGROUND
Neither author has a financial or proprietary interest in any material or method mentioned.
Trivedi
Rupal H
RH
Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA. trivedi@musc.edu
Wilson
M Edward
ME
D017204:Angelman Syndrome / Q000150:complications / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D006956:Hyperopia / Q000209:etiology / Q000601:surgery*; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000601:surgery*; D008297:Male; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult