title: Bullous lupus: an unusual initial presentation of systemic lupus erythematosus in an adolescent girl.
abstract: Bullous systemic lupus erythematosus is a subepidermal blistering disease that occurs only rarely in a subset of patients with systemic lupus erythematosus and even less commonly in pediatric patients. Autoimmunity in bullous systemic lupus erythematosus is characterized by the presence of circulating anti-type VII collagen antibodies. We report here a case of a child whose initial systemic lupus erythematosus presentation was a diffuse bullous eruption.
authors.affiliation: Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Tincopa
authors.forename: Katherine B
authors.initials: KB
authors.lastname: Puttgen
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Sule
authors.forename: Bernard A
authors.initials: BA
authors.lastname: Cohen
authors.forename: Meg R
authors.initials: MR
authors.lastname: Gerstenblith
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D024143:Collagen Type VII / Q000276:immunology; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D008775:Methylprednisolone / Q000627:therapeutic use; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D024143:Collagen Type VII; D006886:Hydroxychloroquine; D003622:Dapsone; D009173:Mycophenolic Acid; D011241:Prednisone; D008775:Methylprednisolone