Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia.
We conducted a prospective household transmission study to examine whether receipt of 2009 trivalent influenza vaccine (TIV) was associated with increased risk of influenza-like illness (ILI) among contacts of confirmed pandemic influenza A(H1N1) 2009 patients. In the week following onset of pandemic illness in a household member, 46 (15%) of 304 TIV-vaccinated contacts, and 174 (15%) of 1,162 unvaccinated contacts developed ILI (p=0.95). Receipt of 2009 TIV had no effect on one's risk of pandemic illness.
Carcione
D
D
Department of Health, Perth, Western Australia, Australia.
Giele
C
C
Goggin
L S
LS
Kwan
K S
KS
Smith
D W
DW
Dowse
G K
GK
Mak
D B
DB
Effler
P
P
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003625:Data Collection; D004196:Disease Outbreaks / Q000517:prevention & control*; D005191:Family Characteristics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D014611:Vaccination / Q000706:statistics & numerical data; D014904:Western Australia / Q000453:epidemiology; D055815:Young Adult
D007252:Influenza Vaccines