title: Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against Anopheles stephensi: a malarial vector mosquito.
abstract: Essential oil of Plectranthus amboinicus was studied for its chemical composition and larvicidal potential against the malarial vector mosquito Anopheles stephensi. Totally 26 compounds were identified by GC and GC-MS. The major chemical compounds were carvacrol (28.65%) followed by thymol (21.66%), α-humulene (9.67%), undecanal (8.29%), γ-terpinene (7.76%), ρ-cymene (6.46%), caryophyllene oxide (5.85%), α-terpineol (3.28%) and β-selinene (2.01%). The larvicidal assay was conducted to record the LC(50) and LC(90) values and the larval mortality was observed after 12 and 24 h of exposure period. The LC(50) values of the oil were 33.54 (after 12 h) and 28.37 ppm (after 24 h). The LC(90) values of the oil were 70.27 (after 12 h) and 59.38 ppm (after 24 h). The results of the present study showed that the essential oil of P. amboinicus is one of the inexpensive and eco-friendly sources of natural mosquito larvicidal agent to control/reduce the population of malarial vector mosquito.
authors.affiliation: Department of Botany, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India.
authors.forename: Annadurai
authors.initials: A
authors.lastname: Senthilkumar
authors.forename: Venugopalan
authors.initials: V
authors.lastname: Venkatesalu
mesh_terms: D000818:Animals; D000852:Anopheles / Q000187:drug effects*; D004199:Disease Vectors; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007928:Lethal Dose 50; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D031346:Plectranthus / Q000737:chemistry*; D016019:Survival Analysis
chemical_list: D007306:Insecticides; D009822:Oils, Volatile