Obstetric aspects of hypoxic ischemic encephalopathy.
Hypoxic ischemic encephalopathy (HIE) describes neonatal encephalopathy that is caused by intrapartum asphyxia and it can result in the long term sequelae of cerebral palsy which is a major cause of disability. The incidence of cerebral palsy has not changed over the last few decades and the challenge to obstetricians remains how best to recognise those babies at risk of this intrapartum insult both before and during labour. Many associations and risk factors are unavoidable or unrecognisable, and others are fairly common and associated with poor predictive value. Intrapartum fetal heart monitoring remains the main focus of attention but how this is best achieved is still the subject of research. Computerised decision support systems built into fetal heart rate monitoring and non-invasive fetal ECG signal pick-up are currently being explored.
Kumar
Sailesh
S
Queen Charlotte's and Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0HS, United Kingdom. sailesh.kumar@imperial.ac.uk
Paterson-Brown
Sara
S
D005260:Female; D005323:Fetal Monitoring; D006340:Heart Rate, Fetal; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000175:diagnosis / Q000473:pathology / Q000517:prevention & control*; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000175:diagnosis / Q000473:pathology / Q000517:prevention & control*; D018743:Perinatal Care; D011247:Pregnancy; D012307:Risk Factors