Mass spectrometry-based protein biomarker discovery: solving the remaining challenges to reach the promise of clinical benefit.
Liotta
Lance A
LA
Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA 20110, USA. lliotta@gmu.edu
Petricoin
Emanuel F
EF
D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006801:Humans; D053758:Nanoparticles; D010051:Ovarian Neoplasms / Q000097:blood* / Q000175:diagnosis; D020543:Proteome / Q000032:analysis*; D012680:Sensitivity and Specificity; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D014408:Biomarkers, Tumor; D020543:Proteome