title: The influence of increased cross-linker chain length in thermosensitive microspheres on potential sun-protection activity.
abstract: The sun protection should involve substances with protecting activity against both UVB and UVA radiation. In this research the evaluation of thermosensitive microspheres as potential molecules for sunscreen formulations was approached, using modified Boots star rating system. The microspheres, thermosensitive N-isopropylacrylamide derivatives, have potential protecting activity against UV radiation. The MX and DX microspheres, with ethylene glycol dimethacrylate and diethylene glycol dimethacrylate crosslinker respectively, due to theirs thermosensitivity exhibit increase in protecting activity against UV radiation when heated to 45 degrees C. The MX microspheres have higher increase in terms of UV absorbance, comparing to DX microspheres, when heated in the 25 degrees C to 45 degrees C range. Studied microspheres have high potential for application as components of sun-screens used in elevated temperatures.
authors.affiliation: University of Maribor, Department for Textile Materials and Design, Laboratory for Chemistry Dyes and Polymers, Slovenia. witold@ktpl.am.wroc.pl
authors.forename: Witold
authors.initials: W
authors.lastname: Musiał
authors.forename: Vanja
authors.initials: V
authors.lastname: Kokol
authors.forename: Bojana
authors.initials: B
authors.lastname: Voncina
mesh_terms: D019540:Area Under Curve; D003432:Cross-Linking Reagents / Q000737:chemistry*; D005026:Ethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry; D006358:Hot Temperature; D008689:Methacrylates / Q000737:chemistry; D008863:Microspheres; D011109:Polymethacrylic Acids / Q000138:chemical synthesis / Q000737:chemistry; D013473:Sunscreening Agents / Q000737:chemistry* / Q000528:radiation effects*; D014466:Ultraviolet Rays
chemical_list: D003432:Cross-Linking Reagents; D005026:Ethylene Glycols; D008689:Methacrylates; D011109:Polymethacrylic Acids; D013473:Sunscreening Agents; C024546:diethylene glycol dimethacrylate polymer; C004919:ethylene dimethacrylate