title: Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-beta-cyclodextrin.
abstract: In this study a complex of naringenin with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) was prepared to improve the hydrophilicity of naringenin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC). The result showed that naringenin had been molecularly dispersed in the HP-beta-CD matrix, not forming a new compound and HPLC analysis showed that the solubility of naringenin in water was enhanced from 4.38 microg/mL to 1,272.31 microg/mL.
authors.affiliation: College of Grain and Food, Henan University of Technology, Zhengzhou 450052, China. wjp1380@163.com
authors.forename: Jiping
authors.initials: J
authors.lastname: Wen
authors.forename: Benguo
authors.initials: B
authors.lastname: Liu
authors.forename: Erdong
authors.initials: E
authors.lastname: Yuan
authors.forename: Yuxiang
authors.initials: Y
authors.lastname: Ma
authors.forename: Yongyi
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D000073738:2-Hydroxypropyl-beta-cyclodextrin; D002152:Calorimetry, Differential Scanning; D044950:Flavanones / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D044950:Flavanones; D047392:beta-Cyclodextrins; D000073738:2-Hydroxypropyl-beta-cyclodextrin; C005273:naringenin