title: Effect of changing pulse rate on profile parameters of perceptual thresholds and loudness comfort levels and relation to ECAP thresholds in recipients of the Nucleus CI24RE device.
abstract: The Nucleus CI24RE ‘Freedom' device offers higher stimulation rates and lower noise levels in action potential measurements (ECAPs) than previous devices. A study including ten European implant teams showed that the effect of changes in rate from 250 to 3500 pulses per second on tilt and curvature of the T and C profiles is insignificant. When changing rate one may change the levels at all electrodes by the same amount. Using an automated procedure ECAPs could be measured quickly and reliably at a noise level of only 1 microV, this did not result in improved correlations between the tilt and curvature parameters of the ECAP profiles and those of the T and C profiles. Average C levels appear to differ markedly among implant centers; a better assessment protocol is required. When increasing stimulus rate one should take into account that this requires higher pulse charges per second and more power consumption.
authors.affiliation: Universitätsklinikum Freiburg, HNO-Klinik, Implant Centrum Freiburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Wesarg
authors.forename: Rolf-Dieter
authors.initials: RD
authors.lastname: Battmer
authors.forename: Laura Cavallé
authors.initials: LC
authors.lastname: Garrido
authors.forename: Norbert
authors.initials: N
authors.lastname: Dillier
authors.forename: Luis
authors.initials: L
authors.lastname: Garcia-Ibáñez
authors.forename: Matthias
authors.initials: M
authors.lastname: Hey
authors.forename: Angel Ramos
authors.initials: AR
authors.lastname: Macias
authors.forename: Alicia Huarte
authors.initials: AH
authors.lastname: Irujo
authors.forename: Andre
authors.initials: A
authors.lastname: Morsnowski
authors.forename: Erwin F
authors.initials: EF
authors.lastname: Offeciers
authors.forename: Andrzej
authors.initials: A
authors.lastname: Zarowski
authors.forename: Joerg
authors.initials: J
authors.lastname: Pesch
authors.forename: Gerben
authors.initials: G
authors.lastname: Rypkema
authors.forename: Guido F
authors.initials: GF
authors.lastname: Smoorenburg
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D001307:Auditory Perception; D001309:Auditory Threshold; D001331:Automation; D003054:Cochlear Implants; D004056:Differential Threshold; D004558:Electric Stimulation / Q000379:methods; D006801:Humans; D008144:Loudness Perception; D008875:Middle Aged; D009622:Noise; D025341:Principal Component Analysis; D055815:Young Adult