BioMOFs: metal-organic frameworks for biological and medical applications.
The class of highly porous materials called metal-organic frameworks offer many opportunities for applications across biology and medicine. Their wide range of chemical composition makes toxicologically acceptable formulation possible, and their high level of functionality enables possible applications as imaging agents and as delivery vehicles for therapeutic agents. The challenges in the area encompass not only the development of new solids but also improvements in the formulation and processing of the materials, including tailoring the morphology and surface chemistry of the frameworks to fit the proposed applications.
McKinlay
Alistair C
AC
EaStChem School of Chemistry, University of St Andrews, Purdie Building, St Andrews, KY16 9ST UK.
Morris
Russell E
RE
Horcajada
Patricia
P
Férey
Gérard
G
Gref
Ruxandra
R
Couvreur
Patrick
P
Serre
Christian
C
D003287:Contrast Media / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry / Q000633:toxicity; D008670:Metals / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D009930:Organic Chemicals / Q000737:chemistry*; D016062:Porosity
D003287:Contrast Media; D004337:Drug Carriers; D008670:Metals; D009930:Organic Chemicals