Palladium-catalyzed direct oxidative alkenylation of azoles.
The direct heteroaromatic sp(2) C-H alkenylation of 2-substituted azole compounds with alkenes proceeds in the presence of Pd(OAc)(2) and AgOAc as catalyst and oxidant, respectively, to afford the corresponding 5-alkenylated azoles in good yields.
Miyasaka
Mitsuru
M
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Hirano
Koji
K
Satoh
Tetsuya
T
Miura
Masahiro
M