title: Phenytoin-associated hypersensitivity syndrome with features of DRESS and TEN/SJS.
abstract: Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, toxic epidermal necrolysis (TEN), and Stevens-Johnson syndrome (SJS) are rare and life-threatening conditions that may be precipitated by anticonvulsive agents. We describe a patient with overlapping features of these hypersensitivity syndromes.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Florida 33136, USA. mviera2@med.miami.edu
authors.forename: Martha H
authors.initials: MH
authors.lastname: Viera
authors.forename: Oliver A
authors.initials: OA
authors.lastname: Perez
authors.forename: Jitendrakumar K
authors.initials: JK
authors.lastname: Patel
authors.forename: Isaac
authors.initials: I
authors.lastname: Jones
authors.forename: Brian
authors.initials: B
authors.lastname: Berman
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D004802:Eosinophilia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010672:Phenytoin / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin