title: Percutaneous injection laryngoplasty in the management of acute vocal fold paralysis.
abstract: OBJECTIVE
  To evaluate the clinical outcome of patients with acute vocal fold paralysis treated with bovine collagen via percutaneous injection laryngoplasty under simple topical anesthesia.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  The charts of 38 consecutive patients with acute unilateral vocal fold paralysis who underwent percutaneous injection laryngoplasty under simple topical anesthesia were reviewed. Symptoms and laryngeal function were assessed pre- and postinjection using the Glottal Function Index (GFI), GRBAS Dysphonia Scale, Functional Outcome Swallowing Scale (FOSS), and maximum phonation time (MPT).
  
  
  RESULTS
  Mean GFI, GRBAS, FOSS, and MPT improved from 13.71 to 7.68, 7.24 to 3.95, 3.70 to 2.20, and 12.87 to 16.45, respectively (P < or = .0001). There were no complications related to the procedure. In seven patients requiring tube feeding secondary to dysphagia and aspiration, injection was successful in restoring oral alimentation in only three patients, with the four failures occurring in patients with multiple cranial neuropathies.
  
  
  CONCLUSIONS
  Percutaneous injection laryngoplasty is a viable option for immediate rehabilitation of acute vocal fold paralysis, and can be performed in the inpatient setting. With dysphagia and aspiration secondary to multiple cranial nerve palsies, medialization of the paralyzed cord alone may be insufficient to restore safe oral alimentation.
authors.affiliation: Division of Laryngology, Department of Otolaryngology/Head and Neck Surgery, Stanford University Medical Center, Stanford, California 94305, USA. edamrose@ohns.stanford.edu
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Damrose
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials / Q000008:administration & dosage*; D003094:Collagen / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007267:Injections; D007830:Larynx; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014826:Vocal Cord Paralysis / Q000628:therapy*; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials; D003094:Collagen