title: ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis.
abstract: The ermB gene was identified in 111 erythromycin resistant isolates of Streptococcus uberis from cases of bovine mastitis associated either with a constitutive (47/111) or an inducible (64/111) phenotype, as well as a phenotypic resistance to all macrolides tested. Resistance to lincosamides was identified in 14 other isolates of S. uberis from bovine mastitis cases and was mainly mediated by the linB gene; resistance conferred by a combination of two genes (linB-lnuD, ermB-linB) was also detected.
authors.affiliation: Agence Française de Sécurité Sanitaire des Aliments, Unité Antibiorésistance et Virulence Bactérienne, 31 Avenue Tony Garnier, 69364 Lyon, France.
authors.forename: Marisa
authors.initials: M
authors.lastname: Haenni
authors.forename: Estelle
authors.initials: E
authors.lastname: Saras
authors.forename: Sophie
authors.initials: S
authors.lastname: Chaussière
authors.forename: Michaël
authors.initials: M
authors.lastname: Treilles
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Madec
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002417:Cattle; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D005260:Female; D005602:France; D005798:Genes, Bacterial; D005838:Genotype; D055231:Lincosamides / Q000494:pharmacology; D018942:Macrolides / Q000494:pharmacology; D008414:Mastitis, Bovine / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D025762:Pristinamycin / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D055231:Lincosamides; D018942:Macrolides; D025762:Pristinamycin; D004917:Erythromycin