An uncommon complementary isochromosome of 46,XY, i(9)(p10),i(9)(q10) in an infertile oligoasthenoteratozoospermic man.
OBJECTIVE
To report a rare case of male infertility associated with oligoasthenoteratozoospermia and complementary isochromosome 46 XY, i(9)(p10),i(9)(q10).


METHODS
Case report.


METHODS
Reference hospital.


METHODS
Infertile oligoastenozoospermic man with complementary isochromosome 46,XY, i(9)(p10),i(9)(q10).


METHODS
Peripheral blood lymphocytes obtained for karyotyping, and florescence in situ hybridization (FISH) analysis for gonadal mosaicism in ejaculated spermatozoa.


METHODS
Physical examination, semen analysis, GBG banding, and FISH procedure.


RESULTS
The semen analysis revealed oligoasthenoteratozoospermia. The lymphocytic karyotype detected a complementary isochromosome 46,XY, i(9)(p10),i(9)(q10), and the FISH procedure showed abnormal sperm.


CONCLUSIONS
This the first report of oligoasthenoteratozoospermia associated with complementary isochromosome 46,XY, i(9)(p10),i(9)(q10).
Guvendag Guven
Emine Seda
ES
Department of Obstetrics and Gynecology, School of Medicine, Rize University, Rize, Turkey. emineseda@yahoo.com
Dilbaz
Serdar
S
Ceylaner
Serdar
S
Acar
Hasan
H
Cinar
Ozgur
O
Ozdegirmenci
Ozlem
O
Karcaaltincaba
Deniz
D
D000328:Adult; D053627:Asthenozoospermia / Q000235:genetics*; D002871:Chromosome Banding; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D018404:Isochromosomes; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics