Description of the first acute bovine diarrhea virus-2 outbreak in Israel.
This is the first report of an acute and fatal outbreak of bovine diarrhea virus (BVDV)-2 infection in Israel. The clinical presentation varied with the age of the affected animals with a bovine-respiratory-complex-like syndrome in young stock, and diarrhea and dysentery only in the lactating stock. Enteritis first appeared in one shed of post-parturient cows; it spread for 6 weeks, until at least 30% of the lactating stock contracted enteritis or dysentery. At the same time, dairy calves aged 10-90 days exhibited severe respiratory disease. Of 79 animals that died, 13/350 (3.7%) were adult lactating cows, and 66/1100 (6%) were young feedlot calves. Phylogenetic analysis of the isolated virus revealed a 95% identity with the corresponding genome parts of various BVDV type 2 sequences. The route of introduction of BVDV-2 into Israel could not be elucidated.
Friedgut
Orly
O
Virology Division, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
Rotenberg
Ditza
D
Brenner
Jacob
J
Yehuda
Stram
S
Paz
Rita
R
Alpert
Nir
N
Ram
Avi
A
Yadin
Hagay
H
Grummer
Beatrice
B
D000208:Acute Disease; D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000453:epidemiology*; D002417:Cattle; D030242:Diarrhea Virus 2, Bovine Viral / Q000302:isolation & purification*; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D007557:Israel / Q000453:epidemiology; D008297:Male