Quetiapine-induced hyperventilation and dyspnea.
OBJECTIVE
Quetiapine is an atypical antipsychotic with favorable properties in the treatment of bipolar disorder, but it has recently been associated with respiratory dysfunction.


METHODS
In this case report, we describe a patient who developed quetiapine-induced hyperventilation and dyspnea after being treated with quetiapine.


RESULTS
To our knowledge, this is the first case presented with quetiapine-induced hyperventilation in a patient with bipolar disorder.


CONCLUSIONS
We recommend a quick reduction of the quetiapine dosage and a change to an alternative antipsychotic for patients treated with quetiapine, who report such respiratory symptoms without a somatic cause for the symptoms.
Mutschler
Jochen
J
Department of General and Social Psychiatry, Psychiatric University Hospital Zurich, Zurich, Switzerland. jochen.mutschler@puk.zh.ch
Obermann
Caitriona
C
Grosshans
Martin
M
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D003987:Dibenzothiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D004417:Dyspnea / Q000139:chemically induced* / Q000150:complications; D006801:Humans; D006985:Hyperventilation / Q000139:chemically induced* / Q000150:complications; D008297:Male; D000069348:Quetiapine Fumarate; D056152:Respiratory Rate / Q000187:drug effects
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate