title: Effects of propofol on the cardiac conduction system.
abstract: OBJECTIVE
  Some studies have demonstrated that the use of propofol is occasionally associated with bradyarrhythmias or reversion of arrhythmias to sinus rhythm. This property of propofol suggests interference with the Cardiac Conduction System (CCS).
  
  
  BACKGROUND
  A review of the main contemporary articles on the use of propofol in the presence of cardiac arrhythmias was undertaken. The authors describe pathophysiological mechanisms of supraventricular tachyarrhythmias (SVT) and occasional interferences caused by propofol on the CCS.
  
  
  CONCLUSIONS
  The studies undertaken so far seem to indicate that propofol probably interferes in automatic SVT (at least in children), but not in reentrant tachyarrhythmias.
authors.affiliation: Instituto de Cardiologia de Porto Alegre. paulowarpe@gmail.com
authors.forename: Paulo
authors.initials: P
authors.lastname: Warpechowski
authors.forename: Ari Tadeu Lírio
authors.initials: AT
authors.lastname: dos Santos
authors.forename: Paulo José Irigon
authors.initials: PJ
authors.lastname: Pereira
authors.forename: Gustavo Glotz
authors.initials: GG
authors.lastname: de Lima
mesh_terms: D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D000818:Animals; D006329:Heart Conduction System / Q000187:drug effects*; D006801:Humans; D015742:Propofol / Q000494:pharmacology*
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol