Citric acid inhibits a bacterial ceramidase and alleviates atopic dermatitis in an animal model.
Inoue
Hiroyuki
H
Institute of Microbial Chemistry, Numazu, Microbial Chemistry Research Foundation, Miyamoto, Numazu-shi, Shizuoka, Japan.
Someno
Tetsuya
T
Kawada
Manabu
M
Ikeda
Daishiro
D
D000818:Animals; D045744:Cell Line, Tumor; D055572:Ceramidases / Q000037:antagonists & inhibitors*; D002518:Ceramides / Q000378:metabolism; D019343:Citric Acid / Q000008:administration & dosage / Q000494:pharmacology*; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000201:enzymology / Q000382:microbiology; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology
D002518:Ceramides; D004791:Enzyme Inhibitors; D019343:Citric Acid; D055572:Ceramidases