title: [Study of clinical application of aberration-free aspheric intraocular lens].
abstract: OBJECTIVE
  To compare spherical aberration, visual quality and apparent accommodation between pseudophakic patients with an aberration-free aspheric intraocular lens (IOL) and patients with a spherical IOL.
  
  
  METHODS
  A prospective study of 130 consecutive cases (132 eyes) was conducted. All cataract patients underwent phacoemulsification were randomized to receive an aberration-free aspheric IOL (Akreos AO, Bausch & Lomb) or a spherical IOL (KS-1, Cannon Staar). Spherical aberration of total eye, best corrected visual acuity (BCVA), near visual acuity (NVA), contrast sensitivity, glare sensitivity and apparent accommodation were measured. Data were analyzed using chi-square test and independent t-test.
  
  
  RESULTS
  The mean spherical aberration in eyes with a Tecnis IOL [(0.141 +/- 0.070) microm] was significantly lower than that of eyes with a spherical IOL [(0.210 +/- 0.108) microm; t = 4.365, P = 0.000]. In addition, Akreos AO IOL provided a better contrast sensitivity at 2.5 degrees visual angle (30.62 +/- 12.50 vs. 25.92 +/- 7.36; t = 2.606, P = 0.010), and improved glare sensitivity at 4.0 degrees (31.25 +/- 8.65 vs. 26.70 +/- 7.98; t = 3.116, P = 0.002), 2.5 degrees (26.35 +/- 8.72 vs. 22.43 +/- 7.35; t = 2.772, P = 0.006) and 1.6 degrees (12.35 +/- 4.01 vs. 9.82 +/- 4.12; t = 3.553, P = 0.001) visual angles. The difference of BCVA, NVA and apparent accommodation between these two groups was not statistically significant.
  
  
  CONCLUSIONS
  The present results demonstrated that an aberration-free aspheric IOL, Akreos AO, may reduce the spherical aberration and improve visual performance of pseudophakic eyes and without negative influence on apparent accommodation as compare to conventional spherical IOL.
authors.affiliation: Eye Center, Affiliated Second Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
authors.forename: Xia-jing
authors.initials: XJ
authors.lastname: Tang
authors.forename: Ke
authors.initials: K
authors.lastname: Yao
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
authors.forename: Xing-chao
authors.initials: XC
authors.lastname: Shentu
authors.forename: Pei-qing
authors.initials: PQ
authors.lastname: Chen
mesh_terms: D000065:Accommodation, Ocular; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000628:therapy*; D015350:Contrast Sensitivity; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged