title: Arsenic health risk assessment in drinking water and source apportionment using multivariate statistical techniques in Kohistan region, northern Pakistan.
abstract: The present study was conducted in Kohistan region, where mafic and ultramafic rocks (Kohistan island arc and Indus suture zone) and metasedimentary rocks (Indian plate) are exposed. Water samples were collected from the springs, streams and Indus river and analyzed for physical parameters, anions, cations and arsenic (As(3+), As(5+) and arsenic total). The water quality in Kohistan region was evaluated by comparing the physio-chemical parameters with permissible limits set by Pakistan environmental protection agency and world health organization. Most of the studied parameters were found within their respective permissible limits. However in some samples, the iron and arsenic concentrations exceeded their permissible limits. For health risk assessment of arsenic, the average daily dose, hazards quotient (HQ) and cancer risk were calculated by using statistical formulas. The values of HQ were found >1 in the samples collected from Jabba, Dubair, while HQ values were <1 in rest of the samples. This level of contamination should have low chronic risk and medium cancer risk when compared with US EPA guidelines. Furthermore, the inter-dependence of physio-chemical parameters and pollution load was also calculated by using multivariate statistical techniques like one-way ANOVA, correlation analysis, regression analysis, cluster analysis and principle component analysis.
authors.affiliation: National Center of Excellence in Geology, University of Peshawar, Pakistan.
authors.forename: Said
authors.initials: S
authors.lastname: Muhammad
authors.forename: M
authors.initials: M
authors.lastname: Tahir Shah
authors.forename: Sardar
authors.initials: S
authors.lastname: Khan
mesh_terms: D000704:Analysis of Variance; D001151:Arsenic / Q000633:toxicity*; D004781:Environmental Exposure; D006801:Humans; D010154:Pakistan; D012044:Regression Analysis; D018570:Risk Assessment; D013054:Spectrophotometry, Atomic; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D014881:Water Supply / Q000032:analysis*
chemical_list: D014874:Water Pollutants, Chemical; D001151:Arsenic