Bile compound-induced DNA damage and repair in bacteriophage T4.
Two bile acids (cholic acid and chenodeoxycholic acid) and two bile salts (sodium cholate and sodium deoxycholate) were shown to inactivate bacteriophage T4. The inactivation was largely reversed when the phage was allowed to undergo recombinational repair, indicating that bile compounds cause DNA damage.
Babatola
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Department of Microbiology and Immunology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.
Bernstein
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