title: [Eosinophilic esophagitis].
abstract: Eosinophilic esophagitis (EE) is a chronic esophageal inflammatory disease mediated by oral antigens with the infiltration of eosinophilic granulocytes. EE can lead to various reflux-like symptoms including dysphagia, progressive strictures and bolus obstruction. EE mostly affects young male population and is associated with atopic disorders and sensitization to oral antigens. Environmental (antigens) and genetic factors (eotaxin-3) have been reported to play role in the pathogenesis of the disease. Symptoms and histological changes are reversible by the elimination of the allergens and the use of anti-inflammatory agents. Remission requires long-term treatment. Strictures with severe symptoms require mechanical balloon dilatation.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar, II. Belgyógyászati Klinika, Budapest. lippaidora@gmail.com
authors.forename: Dóra
authors.initials: D
authors.lastname: Lippai
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Tulassay
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002404:Catheterization; D003680:Deglutition Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D004804:Eosinophils; D004941:Esophagitis / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D004945:Esophagoscopy; D006801:Humans; D035583:Rare Diseases
chemical_list: D000893:Anti-Inflammatory Agents