title: High prevalence of porcine Hokovirus in German wild boar populations.
abstract: Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated to investigate PHoV in German wild boars from five different geographical regions, using a newly established quantitative real-time PCR assay. Analysis of collected liver and serum samples revealed high overall prevalence (32.7%; 51/156) of PHoV in wild boars. The prevalence differed between the regions and increased with age. Two near full-length genomes and a large fragment for three additional isolates from different regions were sequenced and used for phylogenetic analysis. The German PHoV sequences from wild boars showed a close relationship with sequences of isolates from Hong Kong.
authors.affiliation: Robert Koch-Institut, Centre for Biological Security ZBS1, Nordufer 20, Berlin, Germany. adlhochc@rki.de
authors.forename: Cornelia
authors.initials: C
authors.lastname: Adlhoch
authors.forename: Marco
authors.initials: M
authors.lastname: Kaiser
authors.forename: Heinz
authors.initials: H
authors.lastname: Ellerbrok
authors.forename: Georg
authors.initials: G
authors.lastname: Pauli
mesh_terms: D000818:Animals; D005858:Germany / Q000453:epidemiology; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D019219:Parvovirinae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D015995:Prevalence; D034421:Sus scrofa; D013553:Swine Diseases / Q000453:epidemiology / Q000821:virology*