Phylogeny of major intrinsic proteins.
Major intrinsic proteins (MIPs) form a large superfamily of proteins that can be divided into different subfamilies and groups according to phylogenetic analyses. Plants encode more MIPs than o ther organisms and se ven subfamilies have been defined, whereofthe Nodulin26-like major intrinsic proteins (NIPs) have been shown to permeate metalloids. In this chapter we review the phylogeny of MIPs in general and especially of the plant MIPs. We also identify bacterial NIP-like MIPs and discuss the evolutionary implications of this finding regarding the origin and ancestral transport specificity of the NIPs.
Danielson
Jonas A H
JA
Department of Biochemistry, Molecular Protein Science Centre, Centre for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, S-221 00 Lund, Sweden. jonas.danielson@biochemistry.lu.se
Johanson
Urban
U
D020346:Aquaporins / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D001692:Biological Transport; D018076:DNA, Complementary / Q000378:metabolism; D019143:Evolution, Molecular; D017343:Genes, Plant; D008565:Membrane Proteins / Q000378:metabolism; D008670:Metals / Q000737:chemistry; D008954:Models, Biological; D010802:Phylogeny; D010940:Plant Proteins / Q000378:metabolism*
D020346:Aquaporins; D029681:Arabidopsis Proteins; D001426:Bacterial Proteins; D018076:DNA, Complementary; D008565:Membrane Proteins; D008670:Metals; D010940:Plant Proteins; C110065:major intrinsic protein, plant