title: [Colorectal malignancies with respect to hemocoagulation].
abstract: OBJECTIVE
  Relationship between malignants tumors and damage of hemocoagulation is known. The aim is analyse this damage and evaluate the thrombotic markers. MATERIAL AND METHODICS: Authors analyses group of 137 patients with colorectal malignants tumors. They notifyes to relationship between plasmatic preoperative D dimer, PAI-1, F 1+2, Protein C level with controll group.
  
  
  RESULTS
  Especially aggressive forms of colorectal tumours have increased levels of D dimer and PAI-1. Protrombin fragments 1+2 were enhanced in the course of anastomotic dehiscence. Protein C level was reduced in 6.-7. decade and in advanced clinical stage.
  
  
  CONCLUSIONS
  Praeoperative thrombotic markers assays inform about risk of thrombosis and clinical diseases stage. They prefere mini-invasive operations procedures. The maximall validity provides D dimer and PAI-1.
authors.affiliation: Chirurgická klinika FNsP Presov, Slovenská republika. mytnik@fnsppresov.sk
authors.forename: M
authors.initials: M
authors.lastname: Mýtnik
authors.forename: P
authors.initials: P
authors.lastname: Kubisz
authors.forename: J
authors.initials: J
authors.lastname: Stasko
authors.forename: P
authors.initials: P
authors.lastname: Seliga
authors.forename: J
authors.initials: J
authors.lastname: Dano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001777:Blood Coagulation; D015179:Colorectal Neoplasms / Q000097:blood*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011486:Protein C / Q000032:analysis; D019851:Thrombophilia / Q000150:complications* / Q000175:diagnosis
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D011486:Protein C; C036309:fibrin fragment D