title: A facile one-pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones.
abstract: One pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl(3) has been developed. The structures of all the title compounds have been confirmed by IR, (1)H-NMR, (13)CNMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou Universtity, Wenzhou 325035, China. kamenzxh@163.com
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Zhang
authors.forename: Qiulian
authors.initials: Q
authors.lastname: Lin
authors.forename: Ping
authors.initials: P
authors.lastname: Zhong
mesh_terms: D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D009570:Nitriles; D011743:Pyrimidines