title: Intracranial presentation of teratocarcinosarcoma.
abstract: Teratocarcinosarcoma (TCS), an aggressive and extremely rare neoplasm, usually presents as a nasal or paranasal mass. TCS can have intracranial or dural extension from a nasal mass. We found only two instances in the literature that described this lesion as primarily manifesting as an intracranial mass while arising from a primary nasal focus. We describe a patient who had a predominantly frontal-lobe TCS without any symptoms of a primary nasal mass. The gross surgical appearance was a glistening, slimy, firm white mucoid lesion, in contrast to the friable, necrotic and tan-colored lesion usually described. We report a patient with a rare intracranial TCS, and focus on the differential diagnoses of intracranial tumors. Neuropathologists and neurosurgeons should be aware of this mode of presentation for an accurate diagnosis and a well-targeted therapeutic approach.
authors.affiliation: Department of Pathology, B.Y.L. Nair Charitable Hospital, Mumbai, Maharashtra, India.
authors.forename: Shinde
authors.initials: S
authors.lastname: Sweety Vijay
authors.forename: Tyagi Devendra
authors.initials: TD
authors.lastname: Kumar
authors.forename: Balasubramaniam
authors.initials: B
authors.lastname: Srikant
authors.forename: Sawant Hemant Kumar
authors.initials: SH
authors.lastname: Vithal
authors.forename: Kane Shubda
authors.initials: KS
authors.lastname: Vijay
authors.forename: Puranik
authors.initials: P
authors.lastname: Gurunath
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D018243:Teratocarcinoma / Q000473:pathology*