title: [Prognostic factors and reproductive outcomes of borderline ovarian tumors: a review of 186 patients].
abstract: OBJECTIVE
  To determine the clinicopathological characteristics of borderline ovarian tumors and to evaluate their prognostic factors and pregnancy rates/fertility outcomes after conservative surgery.
  
  
  METHODS
  A total of 186 patients with borderline ovarian tumors receiving treatment at our hospital from 1990 to 2007 were retrospectively studied and followed-up post-operatively for at least six months. The effects of clinicopathological characteristics upon recurrence and mortality were analyzed by independent sample t test, Chi-square test, Kaplan-Meier and Cox proportional hazard model.
  
  
  RESULTS
  The median follow-up time was 44 months. One hundred and nine patients underwent conservative surgery and 77 patients underwent radical surgery. Thirty-one relapses were reported. Only 3 died of disease. As demonstrated by multivariate analysis, surgical procedure, stage and pseudomyxoma peritonei were the independent prognostic factors for recurrence.
  
  
  CONCLUSIONS
  The recurrence rate of conservative surgery is higher than that of radical surgery. However, conservative surgery is safe as it does not result in a higher mortality rate.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Tao
authors.forename: Dong-yan
authors.initials: DY
authors.lastname: Cao
authors.forename: Jia-xin
authors.initials: JX
authors.lastname: Yang
authors.forename: Hui-fang
authors.initials: HF
authors.lastname: Huang
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Ling-ya
authors.initials: LY
authors.lastname: Pan
authors.forename: Jing-he
authors.initials: JH
authors.lastname: Lang
authors.forename: Li-na
authors.initials: LN
authors.lastname: Guo
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D005298:Fertility; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult