title: Clinical study of Acrysof IQ aspheric intraocular lenses.
abstract: OBJECTIVE
  To determine whether implantation of anaspheric intraocular lens (SN 60 WF Alcon) results in reduced spherical aberration and improved contrast sensitivity after cataract surgery.
  
  
  METHODS
  Randomized, prospective study. 260 patients/eyes were randomized to receive two intraocular lens types: Alcon Acrysof Natural (136 eyes) and Acrysof IQ (124 eyes). Quality of vision was measured by visual acuity and contrast sensitivity under mesopic and photopic conditions. Ocular aberrations for 4.0- and 6.0-mm pupil were measured with Allegretto Wavelight Analyzer. All ophthalmologic were performed 7, 30 and 90 days postoperatively. Visual function index (VF-14) questionnaires for cataract symptoms were performed 90 days after surgery by all the patients.
  
  
  RESULTS
  After 90 days, all eyes had mean postoperative best spectacle-corrected visual acuity 0.75. Eyes with the Acrysof IQ had significantly higher contrast sensitivity than eyes with the Acrysof Natural at high and middle spatial frequencies. A significant reduction in spherical aberration after Acrysof IQ implantation was achieved. The Acrysof IQ also had lower values of high-order aberration with 4.0- and 6.0-mm pupil when compared with the AcrySof Natural.
  
  
  CONCLUSIONS
  Results show the aspheric Acrysof IQ induced significantly less high-order aberration and spherical aberration compared with the Acrysof Natural. Contrast sensitivity revealed better values with the Acrysof IQ intraocular lens.
authors.affiliation: Ophthalmology Department, Shanghai 9th Hospital, Shanghai Jiaotong University, No. 639 ZhiZao Ju Road, Shanghai, China. flowerrainday@sina.com
authors.forename: Min
authors.initials: M
authors.lastname: Luo
authors.forename: Jing
authors.initials: J
authors.lastname: Ji
authors.forename: Chun
authors.initials: C
authors.lastname: Zhao
authors.forename: Xianqun
authors.initials: X
authors.lastname: Fan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D015350:Contrast Sensitivity; D057108:Corneal Wavefront Aberration; D004867:Equipment Design; D005139:Eyeglasses; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011795:Surveys and Questionnaires; D014792:Visual Acuity