Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei.
A new phenylpropanoid (1), 12-O-caffeoyl-12-hydroxyldodecanoic acid, and a new chalcone (2), 3'-lavandulyl-4-methoxyl-2,2',4',6'-tetrahydroxylchalcone, together with eight known compounds including one chalcone (3), five flavanones (4-8) and two flavonols (9, 10), have been isolated from one of the osteoprotective fractions of Drynaria fortunei (Kunze) J. Sm., which is used as a folk medicine for the treatment of osteoporosis. All these compounds were found for the first time from the genus Drynaria. The structures of the new compounds were elucidated on the basis of spectroscopic analysis.
Wang
Xin-Luan
XL
Musculoskeletal Research Laboratory, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Wang
Nai-Li
NL
Gao
Hao
H
Zhang
Ge
G
Qin
Ling
L
Wong
Man-Sau
MS
Yao
Xin-Sheng
XS
D002599:Chalcone / Q000737:chemistry / Q000302:isolation & purification*; D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D029621:Polypodiaceae / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D002599:Chalcone