title: Luminescent conjugates between dinuclear rhenium(I) complexes and peptide nucleic acids (PNA) for cell imaging and DNA targeting.
abstract: New luminescent dinuclear rhenium(I) tricarbonyl complex-PNA conjugates have been synthesized through a reliable solid-phase synthetic methodology. Their photophysical properties have been measured. The most luminescent Re-PNA conjugate 7 showed interesting two-photon absorption (TPA) properties, that were exploited for imaging experiments, to demonstrate its easy uptake into living cells.
authors.affiliation: Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, I-20133 Milano, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Ferri
authors.forename: Daniela
authors.initials: D
authors.lastname: Donghi
authors.forename: Monica
authors.initials: M
authors.lastname: Panigati
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Prencipe
authors.forename: Laura
authors.initials: L
authors.lastname: D'Alfonso
authors.forename: Ivan
authors.initials: I
authors.lastname: Zanoni
authors.forename: Clara
authors.initials: C
authors.lastname: Baldoli
authors.forename: Stefano
authors.initials: S
authors.lastname: Maiorana
authors.forename: Giuseppe
authors.initials: G
authors.lastname: D'Alfonso
authors.forename: Emanuela
authors.initials: E
authors.lastname: Licandro
mesh_terms: D002460:Cell Line; D004247:DNA / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D049449:Luminescence; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry; D020135:Peptide Nucleic Acids / Q000032:analysis* / Q000737:chemistry*; D012211:Rhenium / Q000032:analysis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D020135:Peptide Nucleic Acids; D012211:Rhenium; D004247:DNA