title: [Pathogenetic characteristics of post stroke affective disorders].
abstract: Fifty patients with affective disorders developed after first cerebral stroke were studied. A spectrum of affective disorders included post-stroke depressions, generalized anxiety disorders, anxiety-depressive disorders and pseudo post-stroke depressions. Platelet serotonin (PS) levels were measured in these patients as well. The levels of PS at the first three days after stroke and their changes towards the 28th day are associated with the development of post-stroke affective disorders. The development of anxiety-depressive disorders in the acute period of stroke is related to the localization of brain lesion focus. The low levels of PS in patients at the first three days after stroke may be the risk factor of delayed affective disorders development.
authors.forename: V I
authors.initials: VI
authors.lastname: Skvortsova
authors.forename: E A
authors.initials: EA
authors.lastname: Petrova
authors.forename: O S
authors.initials: OS
authors.lastname: Brusov
authors.forename: M A
authors.initials: MA
authors.lastname: Savina
authors.forename: N V
authors.initials: NV
authors.lastname: Shaklunova
authors.forename: T P
authors.initials: TP
authors.lastname: Kliushnik
authors.forename: N A
authors.initials: NA
authors.lastname: Georgievskaia
authors.forename: M I
authors.initials: MI
authors.lastname: Faktor
mesh_terms: D000368:Aged; D001792:Blood Platelets / Q000378:metabolism; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000209:etiology* / Q000503:physiopathology*; D012701:Serotonin / Q000032:analysis / Q000378:metabolism; D020521:Stroke / Q000150:complications*
chemical_list: D012701:Serotonin