title: Mindfulness training modifies cognitive, affective, and physiological mechanisms implicated in alcohol dependence: results of a randomized controlled pilot trial.
abstract: Mindfulness training may disrupt the risk chain of stress-precipitated alcohol relapse. In 2008, 53 alcohol-dependent adults (mean age = 40.3) recruited from a therapeutic community located in the urban southeastern U.S. were randomized to mindfulness training or a support group. Most participants were male (79.2%), African American (60.4%), and earned less than $20,000 annually (52.8%). Self-report measures, psychophysiological cue-reactivity, and alcohol attentional bias were analyzed via repeated measures ANOVA. Thirty-seven participants completed the interventions. Mindfulness training significantly reduced stress and thought suppression, increased physiological recovery from alcohol cues, and modulated alcohol attentional bias. Hence, mindfulness training appears to target key mechanisms implicated in alcohol dependence, and therefore may hold promise as an alternative treatment for stress-precipitated relapse among vulnerable members of society.
authors.affiliation: College of Social Work, Florida State University, University Center, Building C, Tallahassee, FL 32306-2570, USA. elgarlan@gmail.com
authors.forename: Eric L
authors.initials: EL
authors.lastname: Garland
authors.forename: Susan A
authors.initials: SA
authors.lastname: Gaylord
authors.forename: Charlotte A
authors.initials: CA
authors.lastname: Boettiger
authors.forename: Matthew O
authors.initials: MO
authors.lastname: Howard
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications / Q000534:rehabilitation*; D001288:Attention / Q000502:physiology; D003072:Cognition Disorders / Q000209:etiology / Q000534:rehabilitation*; D003463:Cues; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D019122:Meditation / Q000379:methods*; D008875:Middle Aged; D019964:Mood Disorders / Q000209:etiology / Q000534:rehabilitation*; D009483:Neuropsychological Tests; D010349:Patient Compliance; D010865:Pilot Projects; D011594:Psychometrics; D011602:Psychophysiologic Disorders / Q000209:etiology / Q000534:rehabilitation*; D011930:Reaction Time / Q000502:physiology; D012649:Self Concept; D016896:Treatment Outcome