title: Femoral and sciatic nerve block with 0.25% bupivacaine for surgical management of diabetic foot syndrome: an anesthetic technique for high-risk patients with diabetic nephropathy.
abstract: A case series of patients with diabetic nephropathy, who underwent lower limb debridement or amputation below the knee during successful combined sciatic and femoral nerve block with bupivacaine 0.25%, is presented. Because impaired nerve conduction in diabetes mellitus results in lower local anesthetic agent requirement, a dose-sparing, minimal effective concentration for surgical anesthesia for peripheral nerve blockade may be more favorable for patients with diabetes and chronic renal disease.
authors.affiliation: Department of Anesthesiology and Reanimation, Baskent University Faculty of Medicine, Ankara 06530, Turkey. aysuinan@yahoo.com
authors.forename: Aysu
authors.initials: A
authors.lastname: Kocum
authors.forename: Ayda
authors.initials: A
authors.lastname: Turkoz
authors.forename: Nesrin
authors.initials: N
authors.lastname: Bozdogan
authors.forename: Esra
authors.initials: E
authors.lastname: Caliskan
authors.forename: Evren H
authors.initials: EH
authors.lastname: Eker
authors.forename: Gulnaz
authors.initials: G
authors.lastname: Arslan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D017719:Diabetic Foot / Q000601:surgery*; D003928:Diabetic Nephropathies / Q000150:complications; D004305:Dose-Response Relationship, Drug; D005260:Female; D005267:Femoral Nerve; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods*; D012584:Sciatic Nerve
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine