[Bilateral emphysematous pyelonephritis caused by Candida glabrata: An exceptional entity].
Acute emphysematous pyelonephritis (AEP) is a severe form of urinary tract infection. It occurs usually in diabetics. The most concerned agents are the Gram-negative bacilli. We report a first case of bilateral AEP due to Candida glabrata, occurred in a 64-year-old diabetic woman. The clinical presentation started with fever and abdominal pains, without signs of urinary tract infection. Within six hours, the patient had developed a septic shock with renal failure and ketoacidosis. The diagnosis was confirmed by CT scan and the pathogen was isolated in urine. Despite antibiotic and antifungal treatment, she died from a septic shock. Acute emphysematous pyelonephritis due to Candida species is rare. However, the addition of antifungal therapy seems justified if a severe emphysematous pyelonephritis is associated with risk factors of Candida infection.
Harrabi
Hajer
H
Service de maladies infectieuses, CHU Hédi Chaker, route El Aïn Km 0,5, 3029 Sfax, Tunisie.
Marrakchi
Chakib
C
Daoud
Emna
E
Elleuch
Emna
E
Hammami
Boussayma
B
Maâloul
Imed
I
Lahiani
Dorra
D
Mnif
Jamel
J
Ben Jemâa
Mounir
M
D041221:Candida glabrata; D002177:Candidiasis / Q000150:complications*; D004646:Emphysema / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D011704:Pyelonephritis / Q000382:microbiology*; D012772:Shock, Septic / Q000382:microbiology