title: Synchronous occurrence of metastatic Wilms tumor and ganglioneuroma.
abstract: We describe a 4-year-old female patient with a persistent paraspinal mass following chemotherapy for Wilms tumor. A discordant response to chemotherapy prompted biopsy of the persistent mass, which revealed a ganglioneuroma. This report highlights the synchronous occurrence of different tumors in the same patient, and suggests that repeat biopsies should be considered when contiguous tumor masses do not respond as expected.
authors.affiliation: Division of Pediatric Hematology-Oncology, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: Cassandra
authors.initials: C
authors.lastname: Moran
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Greiner
authors.forename: Sami W
authors.initials: SW
authors.lastname: Mardam-Bey
authors.forename: Caroline L
authors.initials: CL
authors.lastname: Hollingsworth
authors.forename: Evan
authors.initials: E
authors.lastname: Kulbacki
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Wechsler
mesh_terms: D002675:Child, Preschool; D005260:Female; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008161:Lumbosacral Region; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012186:Retroperitoneal Neoplasms / Q000556:secondary; D013125:Spinal Neoplasms / Q000473:pathology*; D009396:Wilms Tumor / Q000188:drug therapy / Q000556:secondary*