Identification of prolyliminopeptidase-negative Neisseria gonorrhoeae strains in Canada.
Neisseria gonorrhoeae strains that fail to produce the enzyme prolyliminopeptidase have been identified in Canada. Commercial test panels use prolyliminopeptidase activity for identification and to avoid the misdiagnosis of gonorrhea, at least 2 distinct methods for the confirmatory identification of N. gonorrhoeae is imperative.
Martin
Irene E
IE
Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada.
Lefebvre
Brigitte
B
Sawatzky
Pam
P
Hoang
Linda
L
Van Caeseele
Paul
P
Horsman
Greg
G
Ang
Lei
L
Bourgault
Anne-Marie
AM
Ng
Lai-King
LK
D000328:Adult; D000626:Aminopeptidases / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002170:Canada / Q000453:epidemiology; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis* / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000145:classification* / Q000187:drug effects / Q000201:enzymology*; D011159:Population Surveillance / Q000379:methods*; D012703:Serotyping; D055815:Young Adult
D000900:Anti-Bacterial Agents; D000626:Aminopeptidases; C022450:prolyl aminopeptidase