title: Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei.
abstract: A new phenylpropanoid (1), 12-O-caffeoyl-12-hydroxyldodecanoic acid, and a new chalcone (2), 3'-lavandulyl-4-methoxyl-2,2',4',6'-tetrahydroxylchalcone, together with eight known compounds including one chalcone (3), five flavanones (4-8) and two flavonols (9, 10), have been isolated from one of the osteoprotective fractions of Drynaria fortunei (Kunze) J. Sm., which is used as a folk medicine for the treatment of osteoporosis. All these compounds were found for the first time from the genus Drynaria. The structures of the new compounds were elucidated on the basis of spectroscopic analysis.
authors.affiliation: Musculoskeletal Research Laboratory, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, SAR, China.
authors.forename: Xin-Luan
authors.initials: XL
authors.lastname: Wang
authors.forename: Nai-Li
authors.initials: NL
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Gao
authors.forename: Ge
authors.initials: G
authors.lastname: Zhang
authors.forename: Ling
authors.initials: L
authors.lastname: Qin
authors.forename: Man-Sau
authors.initials: MS
authors.lastname: Wong
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Yao
mesh_terms: D002599:Chalcone / Q000737:chemistry / Q000302:isolation & purification*; D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D029621:Polypodiaceae / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D002599:Chalcone