title: Circulating leptin levels in elderly subjects with and without cerebrovasular disease.
abstract: Serum concentrations of leptin was investigated in 40 patients with ischemic stroke, in context of the size of the lesion and also in 40 non-diseased controls, matched according to age, gender and waist hip ratio. Serum leptin concentrations were determined in ng/ml with ELISA and computer tomography (CT) scan was performed in patients to estimate lesion size in cms. Serum leptin concentrations were found to be significantly higher (p < 0.001) in stroke patients (51.61+1.39), compared with controls (37.76+1.207). Moreover, positive correlation (r=0.93) existed between serum leptin level and infarction size in patients with stroke.
authors.affiliation: Department of Biochemistry, Ziauddin University, Karachi. aneelajaleel@hotmail.com
authors.forename: Anila
authors.initials: A
authors.lastname: Jalil
authors.forename: Shahila
authors.initials: S
authors.lastname: Amir
authors.forename: Rehan
authors.initials: R
authors.lastname: Majeed
authors.forename: Farhan
authors.initials: F
authors.lastname: Jalil
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D002561:Cerebrovascular Disorders / Q000097:blood*; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D049629:Waist-Hip Ratio
chemical_list: D001786:Blood Glucose; D020738:Leptin