Comment on M.V. Evans and J.C. Caldwell: evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling of in vivo gas uptake data exposure in female B6C3F1 mice, Toxicol. Appl. Pharmacol., 244, 280-290, 2010.
Anders
M W
MW
Andersen
Melvin E
ME
Clewell
Harvey J
HJ
Gargas
Michael L
ML
Guengerich
F Peter
FP
Reitz
Richard H
RH
D000818:Animals; D019392:Cytochrome P-450 CYP2E1 / Q000378:metabolism*; D005260:Female; D005982:Glutathione Transferase / Q000378:metabolism; D008752:Methylene Chloride / Q000493:pharmacokinetics / Q000633:toxicity*; D051379:Mice; D008954:Models, Biological; D018570:Risk Assessment / Q000379:methods
D008752:Methylene Chloride; D019392:Cytochrome P-450 CYP2E1; D005982:Glutathione Transferase