title: A quantitative meta-analysis of neurocognitive sequelae in survivors of pediatric brain tumors.
abstract: BACKGROUND
  Deficits in neurocognitive functioning are an important area of late effects in survivors of pediatric brain tumors, but a quantitative analysis of the magnitude of these deficits has yet to be conducted.
  
  
  METHODS
  The purpose of the current article is to provide a comprehensive meta-analysis of the literature on long-term neurocognitive effects found in these survivors.
  
  
  RESULTS
  Results indicated significant deficits in both narrow and broad indices of neurocognitive functioning, and the overall magnitude of the effects across all domains ranged from small to large in magnitude (g = -0.45 to -1.43) with a large mean overall effect size of g = -0.91.
  
  
  CONCLUSIONS
  These findings underscore the importance of monitoring the neurocognitive late effects in survivors of pediatric brain tumors, and the need for more consistent consideration of demographic, diagnostic, and treatment-related variables in future research to allow for examination of factors that may moderate these deficits.
authors.affiliation: Department of Psychology and Human Development, Vanderbilt University, Nashville, Tennesse 37203, USA. kristen.e.robinson@vanderbilt.edu
authors.forename: Kristen E
authors.initials: KE
authors.lastname: Robinson
authors.forename: John F
authors.initials: JF
authors.lastname: Kuttesch
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Champion
authors.forename: Charissa F
authors.initials: CF
authors.lastname: Andreotti
authors.forename: Dana W
authors.initials: DW
authors.lastname: Hipp
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bettis
authors.forename: Anna
authors.initials: A
authors.lastname: Barnwell
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Compas
mesh_terms: D001932:Brain Neoplasms / Q000150:complications*; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D009483:Neuropsychological Tests; D011597:Psychomotor Performance; D017741:Survivors / Q000523:psychology*