title: Laser phototherapy in the treatment of periodontal disease. A review.
abstract: Many studies in the literature address the effect of low-power lasers in the management of pathologies related to periodontal tissues. Due to the lack of standardized information and the absence of a consensus, this review presents the current status of laser phototherapy (LPT) in periodontics and discusses its benefits and limits in the treatment of periodontal disease. The literature was searched for reviews and original research articles relating to LPT and periodontal disease. The articles were selected using either electronic search engines or manual tracing of the references cited in key papers. The literature search retrieved references on wound and bone healing, analgesia, hypersensitivity, inflammatory process and antimicrobial photodynamic therapy. Each topic is individually addressed in this review. The current literature suggests that LPT is effective in modulating different periodontal disease aspects in vitro, in animals, and in simple clinical models. Further development of this therapy is now dependent on new clinical trials with more complex study designs.
authors.affiliation: Special Laboratory of Lasers in Dentistry (LELO), Department of Restorative Dentistry, School of Dentistry, University of São Paulo, 227 Cidade Universitária, São Paulo, SP, Brazil. cpeduard@usp.br
authors.forename: Carlos
authors.initials: C
authors.lastname: de Paula Eduardo
authors.forename: Patricia Moreira
authors.initials: PM
authors.lastname: de Freitas
authors.forename: Marcella
authors.initials: M
authors.lastname: Esteves-Oliveira
authors.forename: Ana Cecília Corrêa
authors.initials: AC
authors.lastname: Aranha
authors.forename: Karen Müller
authors.initials: KM
authors.lastname: Ramalho
authors.forename: Alyne
authors.initials: A
authors.lastname: Simões
authors.forename: Marina Stella
authors.initials: MS
authors.lastname: Bello-Silva
authors.forename: Jan
authors.initials: J
authors.lastname: Tunér
mesh_terms: D000698:Analgesia / Q000379:methods; D000818:Animals; D001424:Bacterial Infections / Q000532:radiotherapy; D001842:Bone and Bones / Q000528:radiation effects; D003807:Dentin Sensitivity / Q000532:radiotherapy; D015232:Dinoprostone / Q000096:biosynthesis; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods* / Q000639:trends; D020784:Matrix Metalloproteinase 8 / Q000378:metabolism; D010146:Pain / Q000517:prevention & control; D010510:Periodontal Diseases / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy*; D010778:Photochemotherapy; D012038:Regeneration / Q000528:radiation effects; D014945:Wound Healing / Q000528:radiation effects
chemical_list: D020784:Matrix Metalloproteinase 8; D015232:Dinoprostone