PBDE exposure from food in Ireland: optimising data exploitation in probabilistic exposure modelling.
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants added to plastics, polyurethane foam, electronics, textiles, and other products. These products release PBDEs into the indoor and outdoor environment, thus causing human exposure through food and dust. This study models PBDE dose distributions from ingestion of food for Irish adults on congener basis by using two probabilistic and one semi-deterministic method. One of the probabilistic methods was newly developed and is based on summary statistics of food consumption combined with a model generating realistic daily energy supply from food. Median (intermediate) doses of total PBDEs are in the range of 0.4-0.6 ng/kg(bw)/day for Irish adults. The 97.5th percentiles of total PBDE doses lie in a range of 1.7-2.2 ng/kg(bw)/day, which is comparable to doses derived for Belgian and Dutch adults. BDE-47 and BDE-99 were identified as the congeners contributing most to estimated intakes, accounting for more than half of the total doses. The most influential food groups contributing to this intake are lean fish and salmon which together account for about 22-25% of the total doses.
Trudel
David
D
Institute for Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland.
Tlustos
Christina
C
Von Goetz
Natalie
N
Scheringer
Martin
M
Hungerbühler
Konrad
K
D000328:Adult; D001822:Body Burden; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D005260:Female; D005411:Flame Retardants / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D055768:Halogenated Diphenyl Ethers / Q000032:analysis*; D006801:Humans; D007494:Ireland; D008297:Male; D008954:Models, Biological; D015233:Models, Statistical; D018570:Risk Assessment / Q000379:methods / Q000706:statistics & numerical data; D013997:Time Factors
D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; C086401:pentabromodiphenyl ether