Signal transduction and amplification in a circadian oscillator: interaction between two colored noises.
The signal transduction and amplification in a Neurospora circadian clock system is studied by using the mechanism of internal signal stochastic resonance (ISSR). Two cases have been investigated: the case of no correlations between multiplicative and additive colored noises and the case of correlations between two noises. The results show that, in both cases, the noise-induced circadian oscillations can be transduced with the phenomenon of internal signal stochastic resonance (ISSR). However, the correlation time and intensity of an additive colored noise play different roles for the ISSR, driven by multiplicative colored noise, while the correlation time and intensity of multiplicative colored noise hardly influence the ISSR driven by additive colored noise. In addition, the ISSR can be amplified or suppressed at an appropriate range of the correlation intensity between two colored noises. The fundamental frequency of noise-induced circadian oscillations is hardly shifted with the increment of the intensity and correlation time of colored noises, which implies that the Neurospora system could be resistant to colored noises, exhibit strong vitality and sustain intrinsic circadian rhythms.
Jian-Cheng
Shi
S
College of Chemistry and Life Sciences, Guangxi Teachers Education University, MingXiu Road 175, Nanning, People's Republic of China. mfai668@sina.com
D056926:CLOCK Proteins / Q000235:genetics / Q000378:metabolism; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology* / Q000528:radiation effects; D015966:Gene Expression Regulation, Fungal / Q000528:radiation effects; D005800:Genes, Fungal / Q000235:genetics; D006813:Humidity; D007700:Kinetics; D008027:Light; D008954:Models, Biological; D009491:Neurospora / Q000235:genetics / Q000502:physiology* / Q000528:radiation effects; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics / Q000528:radiation effects; D013696:Temperature; D013997:Time Factors
D012333:RNA, Messenger; D056926:CLOCK Proteins