Circadian rhythms and memory formation.
There has been considerable progress in elucidating the molecular mechanisms that contribute to memory formation and the generation of circadian rhythms. However, it is not well understood how these two processes interact to generate long-term memory. Recent studies in both vertebrate and invertebrate models have shown time-of-day effects on neurophysiology and memory formation, and have revealed a possible role for cycling molecules in memory persistence. Together, these studies suggest that common mechanisms underlie circadian rhythmicity and long-term memory formation.
Gerstner
Jason R
JR
Department of Genetics, University of Wisconsin-Madison, 3476 Genetics and Biotechnology, 425 Henry Mall, Madison, Wisconsin 53706, USA. jrgerstn@gmail.com
Yin
Jerry C P
JC
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology; D008568:Memory / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology*; D056004:Molecular Dynamics Simulation; D012153:Retention, Psychology / Q000502:physiology