title: Differences in symptom occurrence, frequency, intensity, and distress in adolescents prior to and one week after the administration of chemotherapy.
abstract: OBJECTIVE
  The purpose of this study was to describe differences in occurrence, frequency, intensity, and distress of symptoms prior to (T1) and one week following (T2) the administration of intravenous chemotherapy.
  
  
  METHODS
  Longitudinal, descriptive.
  
  
  METHODS
  Two regional children's cancer centers in the Pacific Northwest.
  
  
  METHODS
  A total of 51 adolescents 10 to 19 years old receiving cancer chemotherapy.
  
  
  METHODS
  Memorial Symptom Assessment Scale (MSAS 7-12).
  
  
  RESULTS
  No significant differences were found in symptom occurrence rates between T1 and T2. Fatigue was the only symptom with significantly greater frequency and intensity, and nausea was the only symptom with significantly greater distress at T2 compared with T1.
  
  
  CONCLUSIONS
  Adolescents receiving chemotherapy experience multiple symptoms that persist over time.
  
  
  CONCLUSIONS
  In monitoring for symptoms, nurses need to be aware of the extent to which symptoms are present throughout treatment, as evidenced by these findings that symptom occurrence was significant even prior to receiving a subsequent course of chemotherapy.
authors.affiliation: University of California, San Francisco, CA, USA. johnsoam@ohsu.edu
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Walker
authors.forename: Vivian
authors.initials: V
authors.lastname: Gedaly-Duff
authors.forename: Christine
authors.initials: C
authors.lastname: Miaskowski
authors.forename: Lillian
authors.initials: L
authors.lastname: Nail
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D005221:Fatigue / Q000139:chemically induced; D006801:Humans; D008137:Longitudinal Studies; D009325:Nausea / Q000139:chemically induced; D009369:Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D013312:Stress, Physiological
chemical_list: D000970:Antineoplastic Agents