title: Conservative management of caustic substance ingestion in a pediatric department setting, short-term and long-term outcome.
abstract: Patients with caustic substance ingestion are usually referred to surgery departments where endoscopic evaluation is the first step towards appropriate treatment. The aim of this study was to evaluate the safety and efficacy of conservative management of caustic substance ingestion in a pediatric department setting following a standard protocol including endoscopy in selected cases and conservative treatment based on clinical and endoscopy criteria. In this single center observational study, all children admitted for caustic substance ingestion to a pediatric department over an 8-year-period were managed according to a standard protocol that included endoscopy within 24 hours, if the endoscopy criteria were met, and conservative treatment as judged appropriate according to endoscopic classification. Patients were followed up for 8-10 years. Of the 24 patients (age 4/12 to 6 years) admitted, 14 met the endoscopy criteria. Grade II and III esophageal burns were found in 10/14 patients, and they were treated with H2-blockers, antibiotics, corticosteroids, and nutritional support (parenteral in 8/10). Patients with grade II or III esophageal burns necessitated prolonged hospitalization (x ± standard deviation, 23 ± 3 days; range, 21-30 days). Complications included esophageal strictures (n = 1), treated successfully with dilatations, and bleeding (n = 1) treated conservatively. During the 8- to 10-year follow-up all patients were recorded being well. Based on the study findings it is concluded that conservative management of children with caustic substance ingestion using a standard protocol, including endoscopy as indicated, is feasible within the pediatric department, and conservative treatment on demand is safe and effective in preventing short-term and long-term complications.
authors.affiliation: Pediatric Department, Central Hospital G. Gennimatas, Thessaloniki, Greece. thomaiskl@hotmail.com
authors.forename: T
authors.initials: T
authors.lastname: Karagiozoglou-Lampoudi
authors.forename: C H
authors.initials: CH
authors.lastname: Agakidis
authors.forename: S
authors.initials: S
authors.lastname: Chryssostomidou
authors.forename: K
authors.initials: K
authors.lastname: Arvanitidis
authors.forename: K
authors.initials: K
authors.lastname: Tsepis
mesh_terms: D002057:Burns, Chemical / Q000628:therapy*; D002424:Caustics / Q000633:toxicity*; D002675:Child, Preschool; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004940:Esophageal Stenosis / Q000517:prevention & control*; D004947:Esophagus / Q000293:injuries*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D008297:Male; D010372:Pediatrics; D016896:Treatment Outcome
chemical_list: D002424:Caustics