Ulcerative cutaneous polyarteritis nodosa treated with mycophenolate mofetil and pentoxifylline.
Cutaneous polyarteritis nodosa (CPAN) is a self-limited cutaneous vasculitis characterized by painful nodules, affecting mostly the lower limbs, and livedo reticularis. Despite its benign course, CPAN may display a chronic relapsing evolution with repeated exacerbations. Ulcerative CPAN has a more prolonged evolution and is associated with peripheral neuropathy. We report on a patient with a 20-year history of ulcerative and painful CPAN, refractory to multiple immunosuppressive treatments, treated successfully by mycophenolate mofetil and pentoxifylline.
Kluger
Nicolas
N
Université Montpellier I, Service de Dermatologie, Hôpital Saint-Eloi, CHU de Montpellier, Montpellier, France. icolaskluger@yahoo.fr
Guillot
Bernard
B
Bessis
Didier
D
D000368:Aged; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007871:Leg Ulcer / Q000150:complications / Q000473:pathology; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D010431:Pentoxifylline / Q000008:administration & dosage*; D010488:Polyarteritis Nodosa / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D010431:Pentoxifylline