title: Mental disorders in suicide and undetermined death in the Lundby Study. The contribution of severe depression and alcohol dependence.
abstract: To evaluate the role of severe depression, i.e., depression with melancholic and/or psychotic features and alcohol dependence in suicide and undetermined death. The Lundby Study is a prospective, longitudinal study of a population consisting of 3563 subjects. In a long-term follow up 1947-2006 there were 66 suicide cases, including 19 undetermined deaths. Depression and alcoholism were as expected the major contributors to suicide (44% and 23% respectively). Severe depression with psychotic and/or melancholic features was diagnosed in 66% of all depressions and in 29% of all suicide cases, as compared to 15% for major depression only. Alcohol dependence was related to undetermined death. Major depressive disorder with melancholic and/or psychotic features appears to be an important contributor to accomplished suicide in the depression group, and alcohol dependence appears to be related to undetermined death.
authors.affiliation: Department of Clinical Sciences, Division of Psychiatry, the Lundby Study, Lund University Hospital, St Lars, Lund, Sweden. louise@bradvik.se
authors.forename: Louise
authors.initials: L
authors.lastname: Brådvik
authors.forename: Cecilia
authors.initials: C
authors.lastname: Mattisson
authors.forename: Mats
authors.initials: M
authors.lastname: Bogren
authors.forename: Per
authors.initials: P
authors.lastname: Nettelbladt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000401:mortality*; D002423:Cause of Death; D002648:Child; D015331:Cohort Studies; D015897:Comorbidity; D003866:Depressive Disorder / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health / Q000706:statistics & numerical data*; D008875:Middle Aged; D011618:Psychotic Disorders / Q000401:mortality; D012307:Risk Factors; D012720:Severity of Illness Index; D013405:Suicide / Q000706:statistics & numerical data*; D013406:Suicide, Attempted / Q000706:statistics & numerical data; D015996:Survival Rate; D013548:Sweden / Q000453:epidemiology