Toner and paper-based fabrication techniques for microfluidic applications.
The interest in low-cost microfluidic platforms as well as emerging microfabrication techniques has increased considerably over the last years. Toner- and paper-based techniques have appeared as two of the most promising platforms for the production of disposable devices for on-chip applications. This review focuses on recent advances in the fabrication techniques and in the analytical/bioanalytical applications of toner and paper-based devices. The discussion is divided in two parts dealing with (i) toner and (ii) paper devices. Examples of miniaturized devices fabricated by using direct-printing or toner transfer masking in polyester-toner, glass, PDMS as well as conductive platforms as recordable compact disks and printed circuit board are presented. The construction and the use of paper-based devices for off-site diagnosis and bioassays are also described to cover this emerging platform for low-cost diagnostics.
Coltro
Wendell Karlos Tomazelli
WK
Instituto de Química, Universidade Federal de Goiás, Goiânia-GO, Brazil. wendell@quimica.ufg.br
de Jesus
Dosil Pereira
DP
da Silva
José Alberto Fracassi
JA
do Lago
Claudimir Lucio
CL
Carrilho
Emanuel
E
D000818:Animals; D004867:Equipment Design; D006801:Humans; D056656:Lab-On-A-Chip Devices / Q000191:economics / Q000639:trends*; D046208:Microchip Analytical Procedures / Q000191:economics / Q000639:trends; D044085:Microfluidics / Q000191:economics / Q000295:instrumentation* / Q000639:trends; D010209:Paper