[The role of oral fluoropyrimidines in colorectal cancer treatment--a review].
Oral fluoropyrimidines, such as uracil plus tegafur (UFT), S-1 and capecitabine, have been developed and evaluated in the treatment of colorectal cancer. Their efficacy and safety are not inferior to infusional FU regimens. They provide more convenient therapy and better QOL. Careful observation and management of adverse events to preserve treatment compliance is important.
Toda
Yoko
Y
Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Machida
Nozomu
N
Boku
Narikazu
N
D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D006801:Humans; D011743:Pyrimidines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D011788:Quality of Life
D000970:Antineoplastic Agents; D011743:Pyrimidines; C029269:5-fluoropyrimidine