title: Acquired ichthyosis in a child with autoimmune thyroiditis.
abstract: Acquired ichthyosis is a rare cutaneous disorder characterized by dry, rough skin with prominent scaling, that involves symmetrically the trunk and limbs and especially on the extensor surfaces. It appears most commonly in adults in association with malignant, autoimmune, metabolic, endocrine, and infectious diseases. We describe a child with acquired ichthyosis in whom an autoimmune hypothyroidism was detected; furthermore, replacement therapy with L-thyroxine resulted in complete remission of ichthyosis.
authors.affiliation: Department of Human and Hereditary Pathology, Institute of Dermatology, University of Pavia and Foundation IRCCS Policlinico S. Matteo, Pavia, Italy. vbrazzelli@libero.it
authors.forename: Valeria
authors.initials: V
authors.lastname: Brazzelli
authors.forename: Daniela
authors.initials: D
authors.lastname: Larizza
authors.forename: Francesca
authors.initials: F
authors.lastname: Muzio
authors.forename: Luisa
authors.initials: L
authors.lastname: Fornara
authors.forename: Valeria
authors.initials: V
authors.lastname: Calcaterra
authors.forename: Camilla
authors.initials: C
authors.lastname: Vassallo
authors.forename: Francesca
authors.initials: F
authors.lastname: Scaglia
authors.forename: Giovanna
authors.initials: G
authors.lastname: Borroni
mesh_terms: D001323:Autoantibodies / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D007057:Ichthyosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D007642:Keratosis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000175:diagnosis*; D013974:Thyroxine / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D013974:Thyroxine