title: Single metal nanoparticle spectroscopy: optical characterization of individual nanosystems for biomedical applications.
abstract: The last decade has witnessed the development of a variety of single nanoparticle spectroscopy methods. This has facilitated unprecedented growth of knowledge and understanding of fascinating optical properties of individual metal nanoparticles. This has opened up exciting possibilities of single nanoparticles for applications in many areas including advanced photonics, biomedical imaging and sensing. The field of single nanoparticles detection and characterization is still growing. This paper reviews recent advances in single nanoparticles spectroscopy using both near-field and far-field optics. It covers spectroscopy methods for extremely small (approximately 1 nm) to relatively large nanoparticles (approximately 200 nm) and their optical properties. Different optical techniques are described. Finally, a perspective on possible practical applications of single nanoparticle spectroscopy focusing on biomedical fields is given.
authors.affiliation: Center for Nanoscience and Technology (NDnano), Department of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA. abiswas@nd.edu
authors.forename: Abhijit
authors.initials: A
authors.lastname: Biswas
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Alexandru S
authors.initials: AS
authors.lastname: Biris
mesh_terms: D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry*; D055620:Optical Phenomena; D013059:Spectrum Analysis, Raman
chemical_list: D006046:Gold