Histological determination of the areas enriched in cholinergic terminals and M2 and M3 muscarinic receptors in the mouse central auditory system.
Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor-expressing cell bodies.
Hamada
Satoko
S
Department of Anatomy and Brain Science, Kansai Medical University, Moriguchi, Osaka, Japan.
Houtani
Takeshi
T
Trifonov
Stefan
S
Kase
Masahiko
M
Maruyama
Masato
M
Shimizu
Jun-Ichi
J
Yamashita
Toshio
T
Tomoda
Koichi
K
Sugimoto
Tetsuo
T
D000818:Animals; D001303:Auditory Cortex / Q000737:chemistry / Q000166:cytology*; D001306:Auditory Pathways; D001933:Brain Stem / Q000166:cytology* / Q000378:metabolism; D002799:Cholinergic Fibers / Q000737:chemistry / Q000648:ultrastructure*; D017626:Cochlear Nucleus / Q000737:chemistry / Q000166:cytology; D005829:Geniculate Bodies / Q000737:chemistry / Q000166:cytology*; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D007245:Inferior Colliculi / Q000737:chemistry / Q000166:cytology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D017729:Presynaptic Terminals / Q000737:chemistry / Q000648:ultrastructure; D043585:Receptor, Muscarinic M2 / Q000032:analysis*; D043587:Receptor, Muscarinic M3 / Q000032:analysis*; D050494:Vesicular Acetylcholine Transport Proteins / Q000032:analysis
D043585:Receptor, Muscarinic M2; D043587:Receptor, Muscarinic M3; D050494:Vesicular Acetylcholine Transport Proteins