Relapsing infiltrates after pneumocystis pneumonia in stem cell transplant patients: think about BOOP!
Bronchiolitis Obliterans Organizing Pneumonia (BOOP) can complicate allogeneic haematopoietic stem cell transplantation. It is associated with prior graft-versus-host disease (GVHD) and the case fatality is 21%. In 22%, diagnosis is preceded by tapering the corticosteroids given as a treatment for GVHD. We report a fatal case of BOOP after tapering the corticosteroids that the patient received for a Pneumocystis jirovecii pneumonia after stem cell transplantation.
Deeren
D
D
Dienst Inwendige Ziekten - Hematologie, Heilig-Hartziekenhuis Roeselare-Menen vzw, Roeselare, Belgium. DDeeren@hhr.be
Lammertijn
L
L
Van Dorpe
J
J
D000368:Aged; D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D005938:Glucocorticoids; D008775:Methylprednisolone