Chronic monoarthritis and foot-drop as a paraneoplastic syndrome in prostate cancer.
Paraneoplastic rheumatic symptoms, caused by a malignancy, but not directly related to invasion by the tumor or its metastases are the result of a wide variety of tumor-derived biologic mediators. Recognition of paraneoplastic rheumatic syndromes is important, as it may lead to an early diagnosis of cancer. We report a 71-year-old patient with prostate cancer, presented with chronic monoarthritis of the left ankle and foot-drop. Monoarthritis and foot-drop was resistant to non-steroidal anti-inflammatory drugs and corticosteroids. After tumor resection, synovitis resolved and foot-drop disappeared almost totally.
Kobak
Senol
S
Department of Rheumatology, Manisa Hospital, Manişa Devlet Hastanesi, Manisa, Turkey. senolkobak@yahoo.com
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000843:Ankle Joint / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000209:etiology* / Q000473:pathology; D005534:Foot Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D020233:Gait Disorders, Neurologic / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D020361:Paraneoplastic Syndromes, Nervous System / Q000150:complications* / Q000473:pathology; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome