title: Identification of prolyliminopeptidase-negative Neisseria gonorrhoeae strains in Canada.
abstract: Neisseria gonorrhoeae strains that fail to produce the enzyme prolyliminopeptidase have been identified in Canada. Commercial test panels use prolyliminopeptidase activity for identification and to avoid the misdiagnosis of gonorrhea, at least 2 distinct methods for the confirmatory identification of N. gonorrhoeae is imperative.
authors.affiliation: Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada.
authors.forename: Irene E
authors.initials: IE
authors.lastname: Martin
authors.forename: Brigitte
authors.initials: B
authors.lastname: Lefebvre
authors.forename: Pam
authors.initials: P
authors.lastname: Sawatzky
authors.forename: Linda
authors.initials: L
authors.lastname: Hoang
authors.forename: Paul
authors.initials: P
authors.lastname: Van Caeseele
authors.forename: Greg
authors.initials: G
authors.lastname: Horsman
authors.forename: Lei
authors.initials: L
authors.lastname: Ang
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Bourgault
authors.forename: Lai-King
authors.initials: LK
authors.lastname: Ng
mesh_terms: D000328:Adult; D000626:Aminopeptidases / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002170:Canada / Q000453:epidemiology; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis* / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000145:classification* / Q000187:drug effects / Q000201:enzymology*; D011159:Population Surveillance / Q000379:methods*; D012703:Serotyping; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000626:Aminopeptidases; C022450:prolyl aminopeptidase