title: [Dermatologic aspects of anticoagulation].
abstract: The coagulation system protects the body from uncontrolled blood loss by means of highly regulated processes. In case of an injury the coagulation system instantly switches from controlled blood flow to acute coagulation and thrombus formation with the goal of stopping the blood loss. Minor changes in this well-maintained equilibrium of coagulation and blood flow tip the balance towards uncontrolled blood loss or even fatal thromboembolic events. Iatrogenic manipulation of this highly regulated system is possible with a variety of therapeutic agents. We review the basics of coagulation physiology and then discuss dermatologically relevant aspects of thrombosis prevention, as well as the use of anticoagulants to treat dermatologic diseases.
authors.affiliation: Klinik und Poliklinik für Dermatologie, Universitätsklinikum Münster, von Esmarchstr. 58, 48149, Münster, Deutschland.
authors.forename: V
authors.initials: V
authors.lastname: Meyer
authors.forename: S W
authors.initials: SW
authors.lastname: Schneider
authors.forename: T
authors.initials: T
authors.lastname: Görge
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000188:drug therapy; D004886:Erysipelas / Q000097:blood / Q000188:drug therapy; D006391:Hemangioma / Q000188:drug therapy; D018324:Hemangioma, Capillary / Q000097:blood / Q000188:drug therapy; D006487:Hemostasis / Q000187:drug effects / Q000502:physiology; D006801:Humans; D059885:Kasabach-Merritt Syndrome; D012871:Skin Diseases / Q000097:blood / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000188:drug therapy; D018860:Sneddon Syndrome / Q000097:blood / Q000188:drug therapy; D013262:Stevens-Johnson Syndrome / Q000097:blood / Q000188:drug therapy; D013924:Thrombophlebitis / Q000097:blood / Q000188:drug therapy*; D020246:Venous Thrombosis / Q000097:blood / Q000517:prevention & control
chemical_list: D000925:Anticoagulants