Designed molecular switches: controlling the conformation of benzamido-diphenylacetylenes.
With the goal of creating a molecular switch, the hydrogen-bonded diphenylacetylene structure has been modified such that an equilibrium now exists between two intramolecular H-bonded states. Through X-ray crystallography and (1)H NMR analysis it is shown that this equilibrium can be biased in a predictable manner by modulating the relative acidity of the amide NH's.
Jones
Ian M
IM
Department of Chemistry, Yale University, P.O. Box 20810, New Haven, Connecticut 06520, and Department of Chemistry, Oxford University, 12 Mansfield Road, Oxford OX1 3TA, UK.
Hamilton
Andrew D
AD