Ovarian malignant melanoma without evidence of teratoma.
A 46-year-old woman with ovarian malignant melanoma had advanced intraperitoneal metastasis, retroperitoneal and inguinal lymph node metastases. Extensive debulking surgery was performed and chemotherapy was given. Microscopically, no evidence of other accompanying tumor, such as teratoma was noted. Detailed examination of the patient failed to identify any evidence of another primary melanoma site. It is assumed that spontaneous regression of the primary lesion occurred. Despite the surgery and chemotherapy, the patient died within 2 months of diagnosis. Considering this case, it is assumed that the combination of surgical debulking and chemotherapy are not always beneficial in ovarian malignant melanoma and the prognosis of ovarian malignant melanoma is very poor.
Lee
Seung-Ho
SH
Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, South Korea.
Lee
Kwang-Beom
KB
Shin
Jin-Woo
JW
Chung
Dong-Hae
DH
Park
Chan-Yong
CY
D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery