title: Evaluation of toxicity for heart failure therapeutics: studying effects on the QT interval.
authors.affiliation: Main Line Heart Center and Lankenau Institute for Medical Research, Jefferson Medical College, Wynnewood, Pa 19096, USA.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Link
authors.forename: Gan-Xin
authors.initials: GX
authors.lastname: Yan
authors.forename: Peter R
authors.initials: PR
authors.lastname: Kowey
mesh_terms: D000818:Animals; D002317:Cardiovascular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002423:Cause of Death; D016757:Death, Sudden, Cardiac; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000187:drug effects; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000401:mortality; D008297:Male; D011379:Prognosis; D011817:Rabbits; D018570:Risk Assessment; D016019:Survival Analysis; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000401:mortality; D018675:Toxicity Tests
chemical_list: D002317:Cardiovascular Agents