Unexpected iron(III) chloride-catalysed dimerisation of 1,1,3-trisubstituted-prop-2-yn-1-ols as an expedient route to highly conjugated indenes.
A method to prepare highly conjugated indenes efficiently by iron(III) chloride-catalysed dimerisation of trisubstituted propargylic alcohols under very mild conditions at room temperature is described. The reactions are rapid and operationally straightforward, giving the indene products in good yields and regioselectivity.
Rao
Weidong
W
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Chan
Philip Wai Hong
PW
D001592:Benzyl Alcohols / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D019281:Dimerization; D005290:Ferric Compounds / Q000737:chemistry*; D007192:Indenes / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
D001592:Benzyl Alcohols; D002712:Chlorides; D005290:Ferric Compounds; D007192:Indenes