title: Rapid motion correction in MR-guided high-intensity focused ultrasound heating using real-time ultrasound echo information.
abstract: The objective of this study was to evaluate the feasibility of integrating real-time ultrasound echo guidance in MR-guided high-intensity focused ultrasound (HIFU) heating of mobile targets in order to reduce latency between displacement analysis and HIFU treatment. Experiments on a moving phantom were carried out with MRI-guided HIFU during continuous one-dimensional ultrasound echo detection using separate HIFU and ultrasound imaging transducers. Excellent correspondence was found between MR- and ultrasound-detected displacements. Real-time ultrasound echo-based target tracking during MR-guided HIFU heating is shown with the dimensions of the heated area similar to those obtained for a static target. This work demonstrates that the combination of the two modalities opens up perspectives for motion correction in MRI-guided HIFU with negligible latency.
authors.affiliation: Laboratory for Molecular and Functional Imaging,UMR 5231 CNRS/Université Bordeaux 2, Bordeaux, France.
authors.forename: Philippe Lourenço
authors.initials: PL
authors.lastname: de Oliveira
authors.forename: Baudouin Denis
authors.initials: BD
authors.lastname: de Senneville
authors.forename: Iulius
authors.initials: I
authors.lastname: Dragonu
authors.forename: Chrit T W
authors.initials: CT
authors.lastname: Moonen
mesh_terms: D006361:Heating; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D009038:Motion; D019047:Phantoms, Imaging; D014159:Transducers; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods; D014465:Ultrasonics