Polycythemia vera and increased hemophilic factor VIII causing acute zonal occult outer retinopathy: a case report.
OBJECTIVE
To report a case of acute zonal occult outer retinopathy (AZOOR) caused by Polycythemia and increased levels of Factor VIIIC.


METHODS
Case Report - Interventional.


METHODS
We present a 23 year old male with blurring of vision and loss of lower visual fields in both eyes. Ocular examination suggested the possibility of AZOOR that was confirmed with Fluorescein Angiogram, Visual fields and Electroretinogram. Laboratory work up revealed polycythemia with increased Factor VIIIC. He was treated for the same.


RESULTS
Ocular symptoms improved within 24 hours of treatment with venesection and asprin.


CONCLUSIONS
Polycythemia vera and increased factor VIIIC levels, both venous thromboembolic risk factors are treatable causes of AZOOR.
Mahendradas
Padmamalini
P
Uveitis and Ocular Immunology Services, Narayana Nethralaya, Bangalore, India. padmamalini_m@yahoo.co.in
Shetty
Rohit
R
Avadhani
Kavitha
K
Ross
Cecil
C
Gupta
Anchal
A
Shetty
Bhujang K
BK
D000208:Acute Disease; D001241:Aspirin / Q000627:therapeutic use; D004596:Electroretinography; D005169:Factor VIII / Q000032:analysis*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D018962:Phlebotomy; D011087:Polycythemia Vera / Q000150:complications*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields; D055815:Young Adult
D005169:Factor VIII; D001241:Aspirin