title: Retrogenes reveal the direction of sex-chromosome evolution in mosquitoes.
abstract: The mosquito Anopheles gambiae has heteromorphic sex chromosomes, while the mosquito Aedes aegypti has homomorphic sex chromosomes. We use retrotransposed gene duplicates to show an excess of movement off the An. gambiae X chromosome only after the split with Ae. aegypti, suggesting that their ancestor had homomorphic sex chromosomes.
authors.affiliation: School of Informatics and Computing, Indiana University, Bloomington, IN 47405, USA.
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Toups
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Hahn
mesh_terms: D000330:Aedes / Q000235:genetics; D000818:Animals; D000852:Anopheles / Q000235:genetics; D009033:Culicidae / Q000235:genetics*; D019143:Evolution, Molecular; D020440:Gene Duplication; D024282:Genes, sry; D011995:Recombination, Genetic; D012730:Sex Chromosomes / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics