Time-frequency analysis of accelerometry data for detection of myoclonic seizures.
Four time-frequency and time-scale methods are studied for their ability of detecting myoclonic seizures from accelerometric data. Methods that are used are: the short-time Fourier transform (STFT), the Wigner distribution (WD), the continuous wavelet transform (CWT) using a Daubechies wavelet, and a newly introduced model-based matched wavelet transform (MOD). Real patient data are analyzed using these four time-frequency and time-scale methods. To obtain quantitative results, all four methods are evaluated in a linear classification setup. Data from 15 patients are used for training and data from 21 patients for testing. Using features based on the CWT and MOD, the success rate of the classifier was 80%. Using STFT or WD-based features, the classification success is reduced. Analysis of the false positives revealed that they were either clonic seizures, the onset of tonic seizures, or sharp peaks in "normal" movements indicating that the patient was making a jerky movement. All these movements are considered clinically important to detect. Thus, the results show that both CWT and MOD are useful for the detection of myoclonic seizures. On top of that, MOD has the advantage that it consists of parameters that are related to seizure duration and intensity that are physiologically meaningful. Furthermore, in future work, the model can also be useful for the detection of other motor seizure types.
Nijsen
Tamara M E
TM
Epilepsy Centre Kempenhaeghe, 5590 AB Heeze, The Netherlands. She is now with the Biomedical Sensor Systems Department, Philips Research Laboratories, 5656 AE Eindhoven, The Netherlands. nijsent@kempenhaeghe.nl
Aarts
Ronald M
RM
Cluitmans
Pierre J M
PJ
Griep
Paul A M
PA
D000054:Acceleration; D001132:Arm; D016002:Discriminant Analysis; D004831:Epilepsies, Myoclonic; D005583:Fourier Analysis; D006801:Humans; D015233:Models, Statistical; D018670:Monitoring, Ambulatory / Q000379:methods*; D009068:Movement / Q000502:physiology*; D012640:Seizures / Q000175:diagnosis*; D012815:Signal Processing, Computer-Assisted