Copper-catalyzed intramolecular N-arylation of quinazolinones: facile convergent approach to (-)-circumdatins H and J.
A copper-catalyzed intramolecular N-arylation of a quinazolinone nucleus that furnished the central benzodiazepine core unit has been demonstrated to accomplish an efficient convergent total synthesis of (-)-circumdatins H and J.
Kshirsagar
Umesh A
UA
Division of Organic Chemistry, National Chemical Laboratory (CSIR), Pune 411 008, India.
Argade
Narshinha P
NP
D001570:Benzodiazepinones / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D052999:Quinazolinones / Q000737:chemistry*; D013237:Stereoisomerism
D001570:Benzodiazepinones; D052999:Quinazolinones; C504253:circumdatin H; C549827:circumdatin J; D003300:Copper