title: Preference-based quality of life of end-stage ankle arthritis treated with arthroplasty or arthrodesis.
abstract: BACKGROUND
  Health state values, or "utilities,'' are an important preference-based measure of quality of life used by health economists. This study describes the utilities reported by a multicenter cohort of subjects with end-stage ankle arthritis treated with ankle arthrodesis or total ankle arthroplasty.
  
  
  METHODS
  Subjects with end-stage ankle arthritis were enrolled in a multicenter prospective cohort study. All subjects received either ankle arthrodesis or total ankle arthroplasty. Participants completed baseline SF-36 outcome evaluations preoperatively and at 1-year followup. Preference-based quality of life was assessed using health state values (HSVs) derived from the SF-36 (SF-6D transformation).
  
  
  RESULTS
  107 subjects were included. The mean baseline SF-6D health state value for the TAA group was 0.67 (95% CI 0.64 to 0.69) and 0.66 (95% CI 0.63 to 0.68) for the arthrodesis group. At 1-year followup, the mean reported health state value was 0.73 (95% CI 0.71 to 0.76) for the total ankle arthroplasty group and 0.73 (95% CI 0.70 to 0.76) for the ankle arthrodesis group. The 1-year followup results approach age- and gender-matched US population norms. Health state values poorly correlated with age, however, significant differences between genders were detected.
  
  
  CONCLUSIONS
  These data demonstrate an improvement in preference-based quality of life following ankle arthroplasty or arthrodesis. The results also provide necessary data that can be used in future cost-effectiveness analyses.
authors.forename: Gerard P
authors.initials: GP
authors.lastname: Slobogean
authors.forename: Alastair
authors.initials: A
authors.lastname: Younger
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Apostle
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Marra
authors.forename: Kevin
authors.initials: K
authors.lastname: Wing
authors.forename: Murray
authors.initials: M
authors.lastname: Penner
authors.forename: Tim
authors.initials: T
authors.lastname: Daniels
authors.forename: Mark
authors.initials: M
authors.lastname: Glazebrook
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000843:Ankle Joint; D001168:Arthritis / Q000523:psychology / Q000601:surgery*; D001174:Arthrodesis; D019643:Arthroplasty, Replacement; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D057240:Patient Preference; D011788:Quality of Life; D012737:Sex Factors; D016896:Treatment Outcome