Pancreatic involvement detected with (18)F-FDG PET/CT in disseminated sarcoidosis.
La sarcoidosis is a granulomatous disease of unknown etiology. It may mimic malignancy and may affect multiple organs, with a variable clinical course. Pancreatic involvement is very rare. We present the case of a 78-year-old woman with systemic sarcoidosis whose (18)F-FDG PET/CT scan showed a pancreatic lesion and multiple lymphatic (thoracic and non-thoracic) and visceral lesions. The abnormal (18)F-FDG uptake in the pancreas was limited to the tail. A second (18)F-FDG PET/CT study performed 4 months and 3 weeks after the first PET/CT, following corticosteroid therapy during three and a half months, evidenced partial regression of the disease, with persistent (18)F-FDG pathological uptake in the pancreatic lesion.
Delgado-Bolton
R C
RC
Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, Spain. rbolton@telefonica.net
Arias Navalón
J A
JA
Rodríguez Alfonso
B
B
Delgado-Bolton
A N
AN
Pérez-Castejón
M J
MJ
Sánchez-Escribano
R
R
Cabrera Martín
M N
MN
Lapeña Gutiérrez
L
L
Carreras Delgado
J L
JL
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18