Eye movement abnormalities in multiple sclerosis.
Patients with multiple sclerosis commonly describe visual symptoms that result from several eye movement abnormalities that occur from disruption of critical pathways in the brainstem, cerebellum, and cerebral hemispheres. These abnormalities include internuclear ophthalmoplegia, ocular motor palsy, ocular misalignment, pathologic nystagmus, impaired saccades, saccadic intrusions, and impaired pursuit. Detailed knowledge of these problems and their neuroanatomic localization will aid the physician by guiding diagnosis and therapeutic decision making.
Prasad
Sashank
S
Division of Neuro-Ophthalmology, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Sashank.prasad@uphs.upenn.edu
Galetta
Steven L
SL
D001933:Brain Stem / Q000503:physiopathology; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications*; D009759:Nystagmus, Pathologic / Q000209:etiology; D015835:Ocular Motility Disorders / Q000145:classification / Q000209:etiology* / Q000473:pathology