title: UV-induced TA photoproducts: formation and hydrolysis in double-stranded DNA.
abstract: Hydrolysis of TA photoproduct leads to two derivatives presenting different formation kinetic profiles depending on the oligomer content. The formation efficiency of TA photoproducts in UV-C-irradiated DNA slightly exceeds the formation of the trans,syn cyclobutane pyrimidine dimer at TT sites.
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS UMR 6229, UFR de Pharmacie, Université de Reims Champagne Ardenne, 51 rue Cognacq-Jay, F-51096 Reims Cedex, France.
authors.forename: Saâdia
authors.initials: S
authors.lastname: Asgatay
authors.forename: Agathe
authors.initials: A
authors.lastname: Martinez
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Coantic-Castex
authors.forename: Dominique
authors.initials: D
authors.lastname: Harakat
authors.forename: Coralie
authors.initials: C
authors.lastname: Philippe
authors.forename: Thierry
authors.initials: T
authors.lastname: Douki
authors.forename: Pascale
authors.initials: P
authors.lastname: Clivio
mesh_terms: D004247:DNA / Q000737:chemistry*; D006868:Hydrolysis; D055668:Photochemical Processes; D011740:Pyrimidine Dimers / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D011740:Pyrimidine Dimers; D004247:DNA