title: Predictors of success to weight-loss intervention program in individuals at high risk for type 2 diabetes.
abstract: This study aimed at identifying predictors of success (retention after one year of intervention with ≥5% weight loss) in subjects at high risk for type 2 diabetes enrolled in a lifestyle modification program. Fifty-one individuals with BMI ≥27kg/m(2) and pre-diabetes or metabolic syndrome were enrolled in an individualized multidisciplinary lifestyle intervention to induce weight loss. Subjects were assessed initially with a 16-item weight-loss readiness tool (WLRT) based on stages of change model; a 6-min walk test; and anthropometric measures. The most significant independent factor associated with no success was a lower result to the question "I am capable of doing more physical activity" (P=0.001). The second significant independent predictor was ≤0.5% weight loss 6 weeks after initiating intervention (P=0.01). Excluding subjects with both criteria would have reduced by 52% the number of subjects eligible for the program, decreased the dropout rate from 30% to 17%, and increased the proportion of subjects with ≥5% weight loss at one year from 51% to 80%. Importantly, only 4% of subjects would have been falsely identified as non-responders. These results indicate that a practical WLRT, in combination with early weight-loss response, is helpful to identify subjects with greater chances of success to lifestyle intervention.
authors.affiliation: Department of Medicine, University of Sherbrooke, Sherbrooke, Quebec, Canada.
authors.forename: Weilin
authors.initials: W
authors.lastname: Kong
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Langlois
authors.forename: Carole
authors.initials: C
authors.lastname: Kamga-Ngandé
authors.forename: Claudia
authors.initials: C
authors.lastname: Gagnon
authors.forename: Christine
authors.initials: C
authors.lastname: Brown
authors.forename: Jean-Patrice
authors.initials: JP
authors.lastname: Baillargeon
mesh_terms: D000328:Adult; D001294:Attitude to Health; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000517:prevention & control / Q000523:psychology; D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000517:prevention & control* / Q000523:psychology*; D010352:Patient Dropouts; D010353:Patient Education as Topic; D011236:Prediabetic State / Q000453:epidemiology / Q000517:prevention & control / Q000523:psychology; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012649:Self Concept; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss
chemical_list: D014280:Triglycerides