Synchronous occurrence of metastatic Wilms tumor and ganglioneuroma.
We describe a 4-year-old female patient with a persistent paraspinal mass following chemotherapy for Wilms tumor. A discordant response to chemotherapy prompted biopsy of the persistent mass, which revealed a ganglioneuroma. This report highlights the synchronous occurrence of different tumors in the same patient, and suggests that repeat biopsies should be considered when contiguous tumor masses do not respond as expected.
Moran
Cassandra
C
Division of Pediatric Hematology-Oncology, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.
Greiner
Robert J
RJ
Mardam-Bey
Sami W
SW
Hollingsworth
Caroline L
CL
Kulbacki
Evan
E
Wechsler
Daniel S
DS
D002675:Child, Preschool; D005260:Female; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008161:Lumbosacral Region; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012186:Retroperitoneal Neoplasms / Q000556:secondary; D013125:Spinal Neoplasms / Q000473:pathology*; D009396:Wilms Tumor / Q000188:drug therapy / Q000556:secondary*