title: A case of Y-autosome reciprocal translocation in a Holstein-Friesian bull.
abstract: Cytogenetic evaluation of young bulls of the Polish Holstein-Friesian breed, tested before approving for use in artificial insemination, revealed a carrier of a Y-autosome reciprocal translocation. The applied chromosome banding techniques and fluorescence in situ hybridization (FISH), with the use of locus-specific BAC probes, facilitated description of the translocation as t(Y;21)(p11;q11). The bull presented normal development, including body weight and the size of testicles, as well as libido. Testosterone concentration at the age of 8 months was similar in the carrier and a normal bull of the same age, but at the age of 12 months the testosterone concentration appeared to be lower in the carrier.
authors.affiliation: Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland. switonsk@jay.au.poznan.pl
authors.forename: M
authors.initials: M
authors.lastname: Switonski
authors.forename: I
authors.initials: I
authors.lastname: Szczerbal
authors.forename: W
authors.initials: W
authors.lastname: Krumrych
authors.forename: J
authors.initials: J
authors.lastname: Nowacka-Woszuk
mesh_terms: D000818:Animals; D002417:Cattle; D022202:Chromosomes, Artificial, Bacterial; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D014178:Translocation, Genetic; D014998:Y Chromosome