title: Assessment of likelihood of submucosal invasion in non-polypoid colorectal neoplasms.
abstract: Although of lower prevalence compared with polypoid neoplasms, the non-polypoid neoplasms, especially the depressed type, are important to diagnose because they belong to a distinct biologically aggressive subset, given the high rate of intramucosal or submucosal cancers. The detection and diagnosis of the non-polypoid colorectal neoplasm presents a challenge and an opportunity. Above all, characteristic colonoscopic findings obtained by a combination of conventional colonoscopy and magnifying chromoendoscopy are useful for determination of the invasion depth of non-polypoid colorectal cancers, an essential factor in selecting a treatment modality.
authors.affiliation: Endoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. tamatsud@ncc.go.jp
authors.forename: Takahisa
authors.initials: T
authors.lastname: Matsuda
authors.forename: Adolfo
authors.initials: A
authors.lastname: Parra-Blanco
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Saito
authors.forename: Taku
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D001464:Barium / Q000008:administration & dosage; D003113:Colonoscopy / Q000379:methods*; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D004396:Coloring Agents; D006801:Humans; D007413:Intestinal Mucosa / Q000000981:diagnostic imaging / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D009362:Neoplasm Metastasis / Q000473:pathology; D015995:Prevalence; D018570:Risk Assessment; D014463:Ultrasonography
chemical_list: D004396:Coloring Agents; D001464:Barium