Risperidone-induced QT prolongation following overdose correlates with serum drug concentration and resolves rapidly with no evidence of altered pharmacokinetics.
Pollak
P Timothy
PT
Medicine, Cardiac Sciences and Physiology & Pharmacology, University of Calgary, Calgary, Alberta, Canada. amiokinetics@hotmail.com
Verjee
Zulfikaral H
ZH
Lyon
Andrew W
AW
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000188:drug therapy; D014150:Antipsychotic Agents / Q000097:blood / Q000493:pharmacokinetics* / Q000506:poisoning*; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000139:chemically induced* / Q000378:metabolism*; D062787:Drug Overdose / Q000097:blood; D005260:Female; D006801:Humans; D018967:Risperidone / Q000097:blood / Q000493:pharmacokinetics* / Q000506:poisoning*; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D018967:Risperidone