Recurrence during pregnancy of a conservatively treated early-stage cervical squamous cell carcinoma.
OBJECTIVE
To evaluate the safety of conservative management of early cervical cancer.


METHODS
Case report and analysis of literature guidelines.


METHODS
Academic teaching hospital.


METHODS
A 35-year-old, nulliparous woman treated by simple trachelectomy and pelvic lymphadenectomy for a well-differentiated, 12-mm squamous cell carcinoma infiltrating to a depth of 3 mm (stage Ib1) without lymphovascular space involvement.


METHODS
Follow-up.


METHODS
Recurrence and disease evolution.


RESULTS
Sixteen months after surgery, at 32 weeks' gestation, a local recurrence of 5 cm in diameter was diagnosed, associated with pelvic and interaortocaval lymph node involvement. Despite extensive radiotherapy, chemotherapy, and radical surgery, disease progression could not be halted.


CONCLUSIONS
We report a case of early-stage cervical cancer, conservatively treated by simple trachelectomy and lymphadenectomy, that recurred although none of the known risk factors for recurrence were initially present, and despite the fact that literature guidelines were followed.
Jadoul
Pascale
P
Department of Gynecology, Université Catholique de Louvain, Brussels, Belgium.
Querleu
Denis
D
Squifflet
Jean-Luc
JL
Donnez
Jacques
J
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D018450:Disease Progression; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D010166:Palliative Care; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy