title: Prevalence of disability in an arsenic exposure area in Inner Mongolia, China.
abstract: Long term exposure to arsenic can cause adverse health effects and lead to different levels of disability. The prevalence of arsenical dermatosis is as high as 40% in the Hetao Plain area of Inner Mongolia, but the association between exposure to arsenic in drinking water and the occurrence of disability has not yet been fully examined. The aim of this study was to investigate the prevalence of disability in arsenic-affected villages in Inner Mongolia, China.
  
  
  METHODS
  A cross-sectional study was performed to examine the prevalence of disability. A total of 320 villagers in the age range of 20-39 years were interviewed and examined for disability and arsenical skin lesions. The subjects were classified into a high arsenic group (50 microg L(-1)) and a low arsenic group (<50 microg L(-1)). The relationship between levels of arsenic in drinking water and disability was analyzed using multivariate logistic regression models to estimate the odds ratios and 95% confidence intervals.
  
  
  RESULTS
  The prevalence of disability was 6.88% in the arsenic affected area of Inner Mongolia and 24.72% in the arsenic group 50 microg L(-1). A strong correlation was found between disability and arsenical skin lesions (OR=86.39, 95%CI: 25.45-293.20).
  
  
  CONCLUSIONS
  This suggests that the level of arsenic exposure is a major risk factor for disability. Further research is needed to place the results in a wider context and to determine the exact relationship between arsenic exposure and disability.
authors.affiliation: School of Environmental Science and Public Health, Wenzhou Medical College, Wenzhou, Zhejiang 325035, China.
authors.forename: Guangyun
authors.initials: G
authors.lastname: Mao
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Guo
authors.forename: Ruiying
authors.initials: R
authors.lastname: Kang
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Ren
authors.forename: Zuopeng
authors.initials: Z
authors.lastname: Yang
authors.forename: Yuansheng
authors.initials: Y
authors.lastname: Sun
authors.forename: Chuanwu
authors.initials: C
authors.lastname: Zhang
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Zhang
authors.forename: Haitao
authors.initials: H
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
mesh_terms: D000328:Adult; D001151:Arsenic / Q000633:toxicity*; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D006233:Persons with Disabilities; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D016017:Odds Ratio; D012307:Risk Factors; D012871:Skin Diseases / Q000139:chemically induced / Q000453:epidemiology; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D014874:Water Pollutants, Chemical; D001151:Arsenic