title: Indication for hepatic resection in the treatment of liver metastasis from gastric cancer.
abstract: BACKGROUND
  The significance of hepatic resection for liver metastasis after gastric cancer is not well established. This study aimed to evaluate the effect of hepatic resection in such patients.
  
  
  METHODS
  A retrospective analysis was performed on the outcome of 63 patients with liver metastases without other non-curative factors of gastric cancer who underwent gastrectomy with or without hepatic resection.
  
  
  RESULTS
  Overall 1-, 3-, and 5-year survival rates were 61.9%, 17.2%, and 10.3%, respectively, with a median survival time of 16 months. This increased to 82.3%, 46.4%, and 37.1%, respectively, with a median survival time of 31.2 months in patients who underwent hepatic resection. Multivariate analysis showed that hepatic resection was an independent prognostic factor. Moreover, unilobar liver metastases significantly influenced favorable prognosis in patients receiving hepatic resection by univariate analysis.
  
  
  CONCLUSIONS
  In patients with liver metastases, hepatic resection may be a therapeutic option in the presence of unilobar liver metastases.
authors.affiliation: Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57, Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan. hirochikam@hotmail.com
authors.forename: Hirochika
authors.initials: H
authors.lastname: Makino
authors.forename: Chikara
authors.initials: C
authors.lastname: Kunisaki
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Izumisawa
authors.forename: Motohiko
authors.initials: M
authors.lastname: Tokuhisa
authors.forename: Takashi
authors.initials: T
authors.lastname: Oshima
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Nagano
authors.forename: Shoichi
authors.initials: S
authors.lastname: Fujii
authors.forename: Jun
authors.initials: J
authors.lastname: Kimura
authors.forename: Ryo
authors.initials: R
authors.lastname: Takagawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Kosaka
authors.forename: Hidetaka A
authors.initials: HA
authors.lastname: Ono
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Akiyama
authors.forename: Kuniya
authors.initials: K
authors.lastname: Tanaka
authors.forename: Itaru
authors.initials: I
authors.lastname: Endo
mesh_terms: D000368:Aged; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology*; D015996:Survival Rate