title: Frequency-difference MIT imaging of cerebral haemorrhage with a hemispherical coil array: numerical modelling.
abstract: The feasibility of detecting a cerebral haemorrhage with a hemispherical MIT coil array consisting of 56 exciter/sensor coils of 10 mm radius and operating at 1 and 10 MHz was investigated. A finite difference method combined with an anatomically realistic head model comprising 12 tissue types was used to simulate the strokes. Frequency-difference images were reconstructed from the modelled data with different levels of the added phase noise and two types of a priori boundary errors: a displacement of the head and a size scaling error. The results revealed that a noise level of 3 m degrees (standard deviation) was adequate for obtaining good visualization of a peripheral stroke (volume approximately 49 ml). The simulations further showed that the displacement error had to be within 3-4 mm and the scaling error within 3-4% so as not to cause unacceptably large artefacts on the images.
authors.affiliation: School of Medicine, Swansea University, Swansea, SA2 8PP, UK. massoud.zolgharni@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Zolgharni
authors.forename: H
authors.initials: H
authors.lastname: Griffiths
authors.forename: P D
authors.initials: PD
authors.lastname: Ledger
mesh_terms: D002543:Cerebral Hemorrhage / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008280:Magnetics; D008953:Models, Anatomic; D020521:Stroke / Q000150:complications / Q000175:diagnosis; D014054:Tomography / Q000295:instrumentation* / Q000379:methods