Limonoids from the leaves of Cipadessa baccifera.
Eight new limonoids with four different structural frameworks, including gedunin (1, 2), havanensin (3, 4), mexicanolide (5, 6), and methyl angolensate types (7, 8), together with six known limonoids, were isolated from the leaves of Cipadessa baccifera. Compounds 2 and 5 exhibited moderate cytotoxicity against the HL-60 cell line with an IC(50) value of 20 microM.
Ning
Jing
J
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Di
Ying-Tong
YT
Fang
Xin
X
He
Hong-Pin
HP
Wang
Yuan-Yuan
YY
Li
Yan
Y
Li
Shun-Lin
SL
Hao
Xiao-Jiang
XJ
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D036701:Limonins