Hepatosplenic T cell lymphoma responsive to 2'-deoxycoformycin therapy.
Hepatosplenic T cell lymphoma (HSTL) is a rare condition usually with an aggressive course and a poor prognosis even after extensive treatment. We describe here a patient who presented with hemophagocytosis. The lymphoma had unusual phenotypic features, an indolent course and responded to 20-deoxycoformycin therapy as a single agent. We suggest that this therapy be used in further cases as part of the treatment strategy.
Bennett
Michael
M
Matutes
Estella
E
Gaulard
Philippe
P
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D015649:Pentostatin / Q000008:administration & dosage*; D012074:Remission Induction; D013160:Splenic Neoplasms / Q000188:drug therapy* / Q000473:pathology
D000970:Antineoplastic Agents; D015649:Pentostatin