title: Pharmacotherapy of elderly patients in everyday anthroposophic medical practice: a prospective, multicenter observational study.
abstract: BACKGROUND
  Pharmacotherapy in the older adult is a complex field involving several different medical professionals. The evidence base for pharmacotherapy in elderly patients in primary care relies on only a few clinical trials, thus documentation must be improved, particularly in the field of complementary and alternative medicine (CAM) like phytotherapy, homoeopathy, and anthroposophic medicine. This study describes diagnoses and therapies observed in elderly patients treated with anthroposophic medicine in usual care.
  
  
  METHODS
  Twenty-nine primary care physicians in Germany participated in this prospective, multicenter observational study on prescribing patterns. Prescriptions and diagnoses were reported for each consecutive patient. Data were included if patients were at least 60 years of age. Multiple logistic regression analysis was used to determine factors associated with anthroposophic prescriptions.
  
  
  RESULTS
  In 2005, a total of 12 314 prescriptions for 3076 patients (68.1% female) were included. The most frequent diagnoses were hypertension (11.1%), breast cancer (3.5%), and heart failure (3.0%). In total, 30.5% of the prescriptions were classified as CAM remedies alone, 54.4% as conventional pharmaceuticals alone, and 15.1% as a combination of both. CAM remedies accounted for 41.7% of all medications prescribed (35.5% anthroposophic). The adjusted odds ratio (AOR) for receiving an anthroposophic remedy was significantly higher for the first consultation (AOR = 1.65; CI: 1.52-1.79), treatment by an internist (AOR = 1.49; CI: 1.40-1.58), female patients (AOR = 1.35; CI: 1.27-1.43), cancer (AOR = 4.54; CI: 4.12-4.99), arthropathies (AOR = 1.36; CI: 1.19-1.55), or dorsopathies (AOR = 1.34; CI: 1.16-1.55) and it decreased with patient age (AOR = 0.97; CI: 0.97-0.98). The likelihood of being prescribed an anthroposophic remedy was especially low for patients with hypertensive diseases (AOR = 0.36; CI: 0.32-0.39), diabetes mellitus (AOR = 0.17; CI: 0.14-0.22), or metabolic disorders (AOR = 0.17; CI: 0.13-0.22).
  
  
  CONCLUSIONS
  The present study is the first to provide a systematic overview of everyday anthroposophic medical practice in primary care for elderly patients. Practitioners of anthroposophic medicine prescribe both conventional and complementary treatments. Our study may facilitate further CAM-research on indications of, for example, dementia or adverse drug reactions in the elderly.
authors.affiliation: Havelhoehe Research Institute, Berlin, Germany. ejeschke@havelhoehe.de
authors.forename: Elke
authors.initials: E
authors.lastname: Jeschke
authors.forename: Thomas
authors.initials: T
authors.lastname: Ostermann
authors.forename: Manuela
authors.initials: M
authors.lastname: Tabali
authors.forename: Horst C
authors.initials: HC
authors.lastname: Vollmar
authors.forename: Matthias
authors.initials: M
authors.lastname: Kröz
authors.forename: Angelina
authors.initials: A
authors.lastname: Bockelbrink
authors.forename: Claudia M
authors.initials: CM
authors.lastname: Witt
authors.forename: Stefan N
authors.initials: SN
authors.lastname: Willich
authors.forename: Harald
authors.initials: H
authors.lastname: Matthes
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000887:Anthroposophy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D005791:Patient Care / Q000379:methods* / Q000639:trends; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D011320:Primary Health Care / Q000379:methods* / Q000639:trends; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D004364:Pharmaceutical Preparations