title: Periocular lentigo maligna treated with imiquimod.
abstract: Topical imiquimod 5% cream has been used successfully to treat eyelid basal cell carcinoma, Bowen's disease of the eyelid and eyelid lentigo maligna. We report a case of borderline lentigo maligna on the eyelid that proved difficult to treat with surgery and, when the patient deferred surgery for personal reasons, imiquimod 5% cream was used with complete resolution of the lesion and no recurrence so far over a 3-year period of follow-up. The use of imiquimod in lentigo maligna and around the eye is discussed.
authors.affiliation: Department of Plastic Surgery, Frenchay Hospital, Bristol, UK. jenniferoneill@hotmail.com
authors.forename: Jennifer
authors.initials: J
authors.lastname: O'Neill
authors.forename: Dominic
authors.initials: D
authors.lastname: Ayers
authors.forename: John
authors.initials: J
authors.lastname: Kenealy
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000188:drug therapy* / Q000601:surgery; D000077271:Imiquimod; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod