title: Early side effects after embolization of a carotid body tumor using Onyx.
abstract: The case of a 20-year-old woman with a carotid body tumor of Shamblin class III is reported. Ten hours after preoperative direct intralesional embolization with 20 mL Onyx (ethylene-vinyl alcohol copolymer; Micro Therapeutics, Irvine, Calif), the patient showed symptoms of Horner syndrome and deficits of the hypoglossal and glossopharyngeal nerves. Intraoperative examination 12 hours after Onyx embolization revealed a massive swelling of the hypoglossal and glossopharyngeal nerves. The patient's tongue motility and glossopharyngeal function improved after surgery, but Horner syndrome was still present. Owing to the delayed occurrence of these adverse effects, the optimal time of surgical intervention after Onyx embolization should be discussed and perhaps expedited.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Campus Marburg, Marburg, Germany. wiegand@med.uni-marburg.de
authors.forename: Susanne
authors.initials: S
authors.lastname: Wiegand
authors.forename: Ingo
authors.initials: I
authors.lastname: Kureck
authors.forename: Rene
authors.initials: R
authors.lastname: Chapot
authors.forename: Andreas M
authors.initials: AM
authors.lastname: Sesterhenn
authors.forename: Siegfried
authors.initials: S
authors.lastname: Bien
authors.forename: Jochen A
authors.initials: JA
authors.lastname: Werner
mesh_terms: D002345:Carotid Body Tumor / Q000098:blood supply / Q000175:diagnosis / Q000628:therapy*; D004121:Dimethyl Sulfoxide / Q000009:adverse effects*; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005260:Female; D020435:Glossopharyngeal Nerve Diseases / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000098:blood supply / Q000175:diagnosis / Q000628:therapy*; D006732:Horner Syndrome / Q000209:etiology*; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D011145:Polyvinyls / Q000009:adverse effects*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide