title: Ulcerative cutaneous polyarteritis nodosa treated with mycophenolate mofetil and pentoxifylline.
abstract: Cutaneous polyarteritis nodosa (CPAN) is a self-limited cutaneous vasculitis characterized by painful nodules, affecting mostly the lower limbs, and livedo reticularis. Despite its benign course, CPAN may display a chronic relapsing evolution with repeated exacerbations. Ulcerative CPAN has a more prolonged evolution and is associated with peripheral neuropathy. We report on a patient with a 20-year history of ulcerative and painful CPAN, refractory to multiple immunosuppressive treatments, treated successfully by mycophenolate mofetil and pentoxifylline.
authors.affiliation: Université Montpellier I, Service de Dermatologie, Hôpital Saint-Eloi, CHU de Montpellier, Montpellier, France. icolaskluger@yahoo.fr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Kluger
authors.forename: Bernard
authors.initials: B
authors.lastname: Guillot
authors.forename: Didier
authors.initials: D
authors.lastname: Bessis
mesh_terms: D000368:Aged; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007871:Leg Ulcer / Q000150:complications / Q000473:pathology; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D010431:Pentoxifylline / Q000008:administration & dosage*; D010488:Polyarteritis Nodosa / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D010431:Pentoxifylline