[Eurand Minitabs--the innovative application formula of a pancreatic enzyme complex (Pangrol 10,000, 25,000)].
Modern technology of solid oral drug forms, through the application of macromolecular polymers, generates a number of new formulation solutions. New technologies provide optimal parameters for the release of biologically active substances, increasing by these means pharmacotherapeutic effectiveness of a medicinal product. Basic properties of the innovative Eurand Minitabs technology, making possible the tableting of technologically and applicatively labile substances such as a pancreatic enzyme complex were dicussed. The application of encapsulated minitablets coated with a methacrylic acid copolymer guarantees an optimal range of lipase pharmacological activity.
Kolodziejczyk
Michał Krzysztof
MK
Zakład Technologii Postaci Leku, Katedra Farmacji Stosowanej Uniwersytet Medyczny w Łodzi.
Zgoda
Marian Mikołaj
MM
D000284:Administration, Oral; D002214:Capsules / Q000145:classification; D020099:Coated Materials, Biocompatible; D006863:Hydrogen-Ion Concentration; D008049:Lipase / Q000008:administration & dosage*; D010194:Pancreatin / Q000008:administration & dosage* / Q000737:chemistry; D011109:Polymethacrylic Acids / Q000737:chemistry*; D013607:Tablets / Q000145:classification*
D002214:Capsules; D020099:Coated Materials, Biocompatible; D011109:Polymethacrylic Acids; D013607:Tablets; C038300:methylmethacrylate-methacrylic acid copolymer; D010194:Pancreatin; D008049:Lipase