MicroRNAs: genetically sensitized worms reveal new secrets.
Why do many microRNA gene mutants display no evident phenotype? Multiply mutant worms that are selectively impaired in genetic regulatory network activities have been used to uncover previously unknown functions for numerous Caenorhabditis elegans microRNAs.
Ambros
Victor
V
Department of Molecular Medicine, University of Massachusetts Medical School, 373 Plantation St, Worcester, MA 01605, USA. victor.ambros@umassmed.edu
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D017353:Gene Deletion; D053263:Gene Regulatory Networks / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics* / Q000502:physiology*; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics; D010641:Phenotype
D035683:MicroRNAs