title: Smooth muscle hyperplasia in an asthmatic patient: do we know it all?
abstract: Bronchial smooth muscle hyperplasia is a well-known structural change in asthma. The degree of hyperplasia is related to asthma severity. We report a case of extreme smooth muscle hyperplasia in an asthmatic patient. A 54-year-old female with a diagnosis of analgesic-induced asthma was admitted to our center for nasal polyposis surgery. During her preoperative evaluation, atelectasis of the right middle lobe was detected on chest X-ray. Bronchoscopy revealed the presence of a vegetating polypoid mass obliterating the entrance of the right middle lobe. Histopathological examination of the surgically excised polypoid mass showed benign smooth muscle proliferation with diffuse eosinophilic infiltration. This is a rare case representing an extreme example of benign smooth muscle hyperplasia forming an endobronchial mass in an asthmatic patient.
authors.affiliation: Department of Chest Diseases, Hacettepe University, Faculty of Medicine, Ankara, Turkey. erganb@hacettepe.edu.tr
authors.forename: Begum
authors.initials: B
authors.lastname: Ergan-Arsava
authors.forename: Gul
authors.initials: G
authors.lastname: Karakaya
authors.forename: Pinar
authors.initials: P
authors.lastname: Firat
authors.forename: A Fuat
authors.initials: AF
authors.lastname: Kalyoncu
mesh_terms: D001249:Asthma / Q000473:pathology*; D001980:Bronchi / Q000473:pathology*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged; D009130:Muscle, Smooth / Q000473:pathology*