Mitochondrial dynamics: quantifying mitochondrial fusion in vitro.
Mitochondrial fusion is an essential process for preserving the integrity and stability of mitochondrial DNA; however, regulation of this process remains largely mysterious. In this issue of BMC Biology, Schauss and colleagues describe a simple, reliable, and robust novel assay that allows fusion of mammalian mitochondria to be quantified in vitro.
Jourdain
Alexis
A
Department of Cell Biology, University of Geneva, Switzerland. alexis.jourdain@unige.ch
Martinou
Jean-Claude
JC
D006801:Humans; D008561:Membrane Fusion; D008928:Mitochondria / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000378:metabolism
D024101:Mitochondrial Proteins