title: Laparoscopic biopsy in patients with abdominal lymphadenopathy.
abstract: BACKGROUND
  Abdominal lymphadenopathy (AL) - a common clinical scenario faced by clinicians - often poses a diagnostic challenge. In the absence of palpable peripheral nodes, tissue has to be obtained from the abdominal nodes by image-guided biopsy or surgery. In this context a laparoscopic biopsy avoids the morbidity of a laparotomy.
  
  
  OBJECTIVE
  This retrospective analysis of prospectively collected data represents our experience with laparoscopic biopsy of abdominal lymph nodes.
  
  
  METHODS
  Between October 2000 and November 2005, 28 patients with AL underwent laparoscopic biopsy. Pre-operative radiological imaging studies had identified a nodal mass in 20, a solitary node in 1, a cold abscess in 1 and a mesenteric cystic lesion in 1 patient. In five patients with chronic right lower abdominal pain and normal ultra-sonographic findings mesenteric nodes were identified and biopsied during diagnostic laparoscopy.
  
  
  RESULTS
  The sites of biopsied lymph nodes included para-aortic (10), mesenteric (8), external iliac (3), left gastric (2), obturator (1), aorto-caval (1) and porta hepatis (1). One patient with enlarged peripancreatic nodes mass and another with a mesenteric cystic mass had cold abscesses drained in addition to biopsy. There were no perioperative complications and the median postoperative stay was 2 days (range 1-4 days). Histopathology revealed tuberculosis in 23 patients, reactive adenitis in 2, lymphoma in 1 metastatic carcinoma in 1, and a retroperitoneal sarcoma in 1.
  
  
  CONCLUSIONS
  In patients with AL, laparoscopy provides a safe and effective means of obtaining biopsy. It is of particular value in patients in whom (a) the nodes are small or present in locations unsuitable for image-guided biopsy, (b) adequate tissue cannot be obtained by image-guided biopsy or (c) previously undiagnosed lymphadenopathy is encountered during diagnostic laparoscopy.
authors.affiliation: Department of Minimal Access Surgery, P. D. Hinduja National Hospital, Veer Savarkar Road, Mahim, Mumbai, India.
authors.forename: D S
authors.initials: DS
authors.lastname: Bhandarkar
authors.forename: R S
authors.initials: RS
authors.lastname: Shah
authors.forename: A N
authors.initials: AN
authors.lastname: Katara
authors.forename: M
authors.initials: M
authors.lastname: Shankar
authors.forename: V A
authors.initials: VA
authors.lastname: Chandiramani
authors.forename: T E
authors.initials: TE
authors.lastname: Udwadia