title: Total synthesis of batatoside L.
abstract: The total synthesis of batatoside L (1), a resin glycoside possessing cytotoxicity against laryngeal carcinoma cells, has been completed in a highly convergent manner. The most crucial step in this total synthesis was the efficient construction of the 18-membered macrolactone framework through the Corey-Nicolaou macrolactonization approach.
authors.affiliation: Key Laboratory of Drug Targeting and Delivery Systems, Ministry of Education, and Department of Chemistry of Medicinal Natural Products, School of Pharmacy, Sichuan University, Chengdu 610041, People's Republic of China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xie
authors.forename: San-Yong
authors.initials: SY
authors.lastname: Zhu
authors.forename: Xiao-Qiu
authors.initials: XQ
authors.lastname: Shen
authors.forename: Li-Li
authors.initials: LL
authors.lastname: He
authors.forename: Jin-Song
authors.initials: JS
authors.lastname: Yang
mesh_terms: D027722:Convolvulaceae / Q000737:chemistry*; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D008968:Molecular Conformation; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D012116:Resins, Plant / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D046911:Macromolecular Substances; D009844:Oligosaccharides; D012116:Resins, Plant; C553644:batatoside L