title: Reversible posterior leukoencephalopathy syndrome in a patient of FSGS with heavy proteinuria.
abstract: Reversible posterior leukoencephalopathy syndrome (RPLS) is a neurological syndrome characterized by headache, seizures, and visual loss, often associated with an abrupt increase in blood pressure. It was first described by Hinchey and colleagues in 1996 when they described a case series. RPLS has been described in number of medical conditions, renal dysfunction being one of them. Prompt diagnosis and therapy with antihypertensives, anticonvulsants, removal of any offending medication, and treatment of associated disorder are essential because early treatment might prevent progression to irreversible brain damage. Here, we report a case of young man with focal segmental glomerulosclerosis (FSGS) and heavy proteinuria, who developed classical, clinical, and neurological features of RPLS with complete recovery.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia. dr_zahidnabi@hotmail.com
authors.forename: Zahid
authors.initials: Z
authors.lastname: Nabi
authors.forename: Lutfi
authors.initials: L
authors.lastname: Al Korbi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ghailani
authors.forename: Quaid
authors.initials: Q
authors.lastname: Nadri
authors.forename: Mohamed
authors.initials: M
authors.lastname: Abdelsalam
authors.forename: Mamdouh
authors.initials: M
authors.lastname: Al Baqumi
mesh_terms: D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications*; D006801:Humans; D008297:Male; D054038:Posterior Leukoencephalopathy Syndrome / Q000209:etiology*; D011507:Proteinuria / Q000150:complications*; D012720:Severity of Illness Index; D055815:Young Adult