title: [Manipulation of the human genome: ethics and law].
abstract: The molecular biology has provided the basic tool for geneticists deepening in the molecular mechanisms that influence different diseases. It should be noted the scientific and moral responsibility of the researchers, because the scientists should imagine the moral consequences of the commercial application of genetic tests, since this fact involves not only the individual and their families, but the entire population. Besides being also necessary to make a reflection on how this information from the human genome will be used, for good or bad. The objective of this review was to bring the light of knowledge, data on characteristics of the ethical application of molecular biology, linking it with the rights of human beings. After studying literature, it might be observed that the Human Genome Project has generated several possibilities, such as the identification of genes associated with diseases with synergistic properties, but sometimes modifying behavior to genetically intervene in humans, bringing benefits or social harm. The big challenge is to decide what humanity wants on this giant leap.
authors.affiliation: Universidade de São Paulo, Bauru, SP, Brazil. mariacarolina@usp.br
authors.forename: Maria Carolina Vaz
authors.initials: MC
authors.lastname: Goulart
authors.forename: Flávia Godoy
authors.initials: FG
authors.lastname: Iano
authors.forename: Paulo Maurício
authors.initials: PM
authors.lastname: Silva
authors.forename: Silvia Helena de Carvalho
authors.initials: SH
authors.lastname: Sales-Peres
authors.forename: Arsênio
authors.initials: A
authors.lastname: Sales-Peres
mesh_terms: D005823:Genetics / Q000941:ethics* / Q000331:legislation & jurisprudence*; D015894:Genome, Human; D006801:Humans