title: SCCmec Type IV, PVL-Negative, Methicillin-Resistant Staphylococcus aureus in Cystic Fibrosis Patients from Brazil.
abstract: Twenty seven S. aureus isolates were obtained from cystic fibrosis (CF) patients at a tertiary care hospital in Brazil. Nineteen (70.4%) were methicillin-susceptible S. aureus (MSSA) and eight (29.6%) methicillin-resistant S. aureus (MRSA). Of the MRSA isolates, four had SCCmec type III and four had SCCmec type IV. PVL genes were not detected in any of the MSSA or MRSA isolates. New studies are necessary to evaluate the exact impact of these different MRSA clones in CF patients.
authors.affiliation: Department of Pediatrics, Santa Casa De São Paulo, São Paulo, SP, Brazil. mjmimica@hotmail.com
authors.forename: Marcelo J
authors.initials: MJ
authors.lastname: Mimica
authors.forename: Eitan N
authors.initials: EN
authors.lastname: Berezin
authors.forename: Neiva
authors.initials: N
authors.lastname: Damaceno
authors.forename: Rozane B
authors.initials: RB
authors.lastname: Carvalho
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics*; D015373:Bacterial Typing Techniques; D001938:Brazil; D003550:Cystic Fibrosis / Q000150:complications*; D004269:DNA, Bacterial / Q000235:genetics*; D005098:Exotoxins / Q000235:genetics*; D005838:Genotype; D006761:Hospitals; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D016106:Methicillin Resistance; D058889:Molecular Typing; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D037521:Virulence Factors / Q000235:genetics
chemical_list: D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors