title: HAE international home therapy consensus document.
abstract: Hereditary angioedema (C1 inhibitor deficiency, HAE) is associated with intermittent swellings which are disabling and may be fatal. Effective treatments are available and these are most useful when given early in the course of the swelling. The requirement to attend a medical facility for parenteral treatment results in delays. Home therapy offers the possibility of earlier treatment and better symptom control, enabling patients to live more healthy, productive lives. This paper examines the evidence for patient-controlled home treatment of acute attacks ('self or assisted administration') and suggests a framework for patients and physicians interested in participating in home or self-administration programmes. It represents the opinion of the authors who have a wide range of expert experience in the management of HAE.
authors.affiliation: Department of Immunology, Barts and the London NHS Trust, London, UK. hilary.longhurst@bartsandthelondon.nhs.uk.
authors.forename: Hilary J
authors.initials: HJ
authors.lastname: Longhurst
authors.forename: Henriette
authors.initials: H
authors.lastname: Farkas
authors.forename: Timothy
authors.initials: T
authors.lastname: Craig
authors.forename: Emel
authors.initials: E
authors.lastname: Aygören-Pürsün
authors.forename: Claire
authors.initials: C
authors.lastname: Bethune
authors.forename: Janne
authors.initials: J
authors.lastname: Bjorkander
authors.forename: Konrad
authors.initials: K
authors.lastname: Bork
authors.forename: Laurence
authors.initials: L
authors.lastname: Bouillet
authors.forename: Henrik
authors.initials: H
authors.lastname: Boysen
authors.forename: Anette
authors.initials: A
authors.lastname: Bygum
authors.forename: Teresa
authors.initials: T
authors.lastname: Caballero
authors.forename: Marco
authors.initials: M
authors.lastname: Cicardi
authors.forename: John
authors.initials: J
authors.lastname: Dempster
authors.forename: Mark
authors.initials: M
authors.lastname: Gompels
authors.forename: Jimmy
authors.initials: J
authors.lastname: Gooi
authors.forename: Sofia
authors.initials: S
authors.lastname: Grigoriadou
authors.forename: Ursula
authors.initials: U
authors.lastname: Huffer
authors.forename: Wolfhart
authors.initials: W
authors.lastname: Kreuz
authors.forename: Marcel M
authors.initials: MM
authors.lastname: Levi
authors.forename: Janet
authors.initials: J
authors.lastname: Long
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Martinez-Saguer
authors.forename: Michel
authors.initials: M
authors.lastname: Raguet
authors.forename: Avner
authors.initials: A
authors.lastname: Reshef
authors.forename: Tom
authors.initials: T
authors.lastname: Bowen
authors.forename: Bruce
authors.initials: B
authors.lastname: Zuraw