title: Peculiar findings in a case of bilateral uveal pigmented lesions.
abstract: OBJECTIVE
  To describe a probable case of bilateral diffuse uveal melanocytic proliferation (BDUMP) with unusual manifestations and prognosis.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Clinical follow-up of the patient lasting 50 months with recurrent fundus examination using color photographs, angiography, ultrasound, and optical coherence tomography. Serological and radiological investigations were performed to assess possible extraocular alterations.
  
  
  RESULTS
  In both eyes patch-shaped pigmented alterations of the fundus were revealed. Fluorescein and indocyanine angiography evidenced corresponding areas of hyperfluorescent pinpoints and subtle serous detachment of the neurosensory retina, respectively. Ten months after the initial evaluation, flat pigmentary lesions appeared in the superior scleral surface of the right eye and underwent histological examination. After an initial decrease in visual acuity, the patient experienced a spontaneous recovery. He did not develop cataracts or any systemic malignancies.
  
  
  CONCLUSIONS
  Although not all the criteria for the diagnosis were fulfilled, clinical findings were compatible with BDUMP. The presence of scleral pigmented lesions and the good visual prognosis may widen the spectrum of this rare disease.
authors.affiliation: Institute of Ophthalmology, University of Parma, Via Gramsci 14, Parma, Italy. paolo.mora@unipr.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Mora
authors.forename: Stefania
authors.initials: S
authors.lastname: Gonzales
authors.forename: Pellegrino
authors.initials: P
authors.lastname: Crafa
authors.forename: Arturo
authors.initials: A
authors.lastname: Carta
authors.forename: Yan
authors.initials: Y
authors.lastname: Guex-Crosier
authors.forename: Leonidas
authors.initials: L
authors.lastname: Zografos
mesh_terms: D000792:Angiography; D049109:Cell Proliferation; D005128:Eye Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D012075:Remission, Spontaneous; D012163:Retinal Detachment / Q000150:complications / Q000175:diagnosis; D012171:Retinal Vessels / Q000000981:diagnostic imaging; D012590:Sclera / Q000473:pathology; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D014602:Uvea / Q000473:pathology*; D014792:Visual Acuity