title: Intramedullary spinal cord and cauda equina metastasis of breast carcinoma: case report.
abstract: OBJECTIVE
  We present a case report of a female patient with metastasis of breast carcinoma to the medullary conus and cauda equina.
  
  
  METHODS
  A 48-year-old woman with a history of breast tumor, suddenly felt severe weakness and numbness of the lower extremities. MRI of the spine disclosed a mass lesion within the medullary conus, with leptomeningeal involvement of cauda equina at the spinal level L1. Laminectomy was performed and partial resection of the medullary conus tumor and especially release of nerve roots of cauda equina was achieved using microsurgical techniques.
  
  
  RESULTS
  Her clinical status, especially right leg weakness and sensory loss in the lower extremities have immediately improved but bladder dysfunction remained and she was unable to walk. The histological picture and immunophenotype indicates the presence of metastatic ductal adenocarcinoma of the mammary gland. Patient died 4 months after the spinal cord and cauda equina surgery.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of successful surgical treatment of metastatic leptomeningeal infiltration of breast carcinoma.
authors.affiliation: Department of Neurosurgery, Palacky University and University Hospital Olomouc, Czech Republic. lumir.hrabalek@seznam.cz
authors.forename: Lumir
authors.initials: L
authors.lastname: Hrabalek
authors.forename: Ondrej
authors.initials: O
authors.lastname: Kalita
authors.forename: Hana
authors.initials: H
authors.lastname: Studentova
authors.forename: Jana
authors.initials: J
authors.lastname: Jankova
authors.forename: Jiri
authors.initials: J
authors.lastname: Ehrmann
authors.forename: Radek
authors.initials: R
authors.lastname: Trojanec
authors.forename: Marian
authors.initials: M
authors.lastname: Hajduch
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000556:secondary* / Q000601:surgery; D002420:Cauda Equina; D005260:Female; D006801:Humans; D008875:Middle Aged; D013120:Spinal Cord Neoplasms / Q000556:secondary* / Q000601:surgery