Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection.
Bio-bar-code dendrimer-like DNA (bbc-DL-DNA) is employed as a label for the amplification assay of cancer cells in combination with the newly explored chemiluminescence (CL) system of luminol-H(2)O(2)-Ru(3+) and specificity of structure-switching aptamers selected by cell-based SELEX.
Bi
Sai
S
Key Laboratory of Eco-chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Hao
Shuangyuan
S
Li
Li
L
Zhang
Shusheng
S
D015374:Biosensing Techniques / Q000379:methods*; D045744:Cell Line, Tumor; D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D004587:Electrophoresis, Agar Gel; D006801:Humans; D049408:Luminescent Agents / Q000737:chemistry*; D008163:Luminescent Measurements / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D009369:Neoplasms / Q000175:diagnosis; D012428:Ruthenium / Q000737:chemistry*; D013499:Surface Properties
D050091:Dendrimers; D049408:Luminescent Agents; D012428:Ruthenium; D004247:DNA