Obesity and age affect male fertility potential.
A case-cohort study of 2,157 patients, aged 17-67 years was performed to assess the impact of body mass index and age on male fertility. Using a multiple regression analysis across the total cohort, only age correlated significantly with all spermiogram parameters and serum hormones, but in patients aged 20-30 years (n = 617) the total sperm count was significantly negatively correlated with body mass index.
Paasch
Uwe
U
Department of Dermatology, Training Center of the European Academy of Andrology, University of Leipzig, Leipzig, Germany. uwe.paasch@medizin.uni-leipzig.de
Grunewald
Sonja
S
Kratzsch
Juergen
J
Glander
Hans-Juergen
HJ
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000097:blood / Q000502:physiology*; D015992:Body Mass Index; D005298:Fertility / Q000502:physiology*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D007265:Inhibins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D055101:Semen Analysis; D055815:Young Adult
C422364:inhibin B; D007265:Inhibins; D005640:Follicle Stimulating Hormone