title: 10-year review of endolymphatic sac surgery for intractable meniere disease.
abstract: OBJECTIVE
  To review our 10-year experience of endolymphatic sac surgery (ESS) for intractable Meniere disease (MD).
  
  
  METHODS
  Retrospective chart review and survey.
  
  
  METHODS
  Tertiary care centre.
  
  
  METHODS
  Patients presenting for ESS from 1998 to 2007 were reviewed using the 1995 American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guidelines. A quality of life (QOL) questionnaire was mailed out using the Dillman method.
  
  
  METHODS
  (1) 1995 AAO-HNS hearing stage, vertigo class, and functional level; (2) complications and secondary treatments; (3) a 40-question, disease-specific, validated QOL questionnaire (Meniere's Disease Outcome Questionnaire).
  
  
  RESULTS
  Thirty patients (33 ears) had ESS (63.6% male, mean age 49 years, mean follow-up 30.6 months). Vertigo control was 35.5% class A, 29.0% class B, 6.5% class C, 0% class D, 3.2% class E, and 25.8% class F. If class A and B are considered successful, then 64.5% were successful. Hearing stage improved in 14.8%, remained the same in 51.9%, and worsened in 33.3%. Average preoperative functional level was 4.3 and postoperative level was 3.5 (p = .0016). Secondary treatment after ESS was performed in 26%. Three patients (10.0%) had profound sensorineural hearing loss. Twenty-five questionnaire responses (75.8%) were received. There was a significant increase in QOL scores (p = .000001), and 80% had an improvement in QOL scores.
  
  
  CONCLUSIONS
  ESS is a surgical option for MD that offers relief from vertigo in selected patients, but patients need to be cautioned about the risk of hearing loss and the requirement for subsequent destructive treatment in a significant proportion of cases.
authors.affiliation: Department of Otolaryngology, University of Western Ontario, London, Ontario.
authors.forename: Amanda
authors.initials: A
authors.lastname: Hu
authors.forename: Lorne S
authors.initials: LS
authors.lastname: Parnes
mesh_terms: D004712:Endolymphatic Sac / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005684:Gait / Q000502:physiology; D006309:Hearing / Q000502:physiology; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D013506:Otologic Surgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014717:Vertigo / Q000209:etiology / Q000503:physiopathology / Q000601:surgery