title: [Practical aspects of sepsis from oral bacterial infections].
abstract: Infections of the oral cavity are an important morbidity problem due to their frequency, their pluribacterial ethiology as well as their potential severe evolution, especially with the immunodepressive. The odontogenic infections are considered to be the cause of 40% of the deep throat infections. The infections of the submentonier space occur through direct extension from the mandibular incisors, those of the sublingual space start from the anterior mandibular teeth and those of the retrofaringian space start from the mandibular molar teeth.
  
  
  METHODS
  The present study included 24 pacients diagnosed with oral sepsis in Iaşi Infectious Diseases Clinic. We analysed the ethiology and the clinical response to the administered antibiotherapy.
  
  
  RESULTS
  In several immunodepressed patients (with diabetus melitus, neutropenia, liver disfunction, carcinomas, tuberculosis) was noted sistemic evolution of odontogenic infection and they mainly came from the Surgery Clinics, where surgery was performed for the drainage of collections. Etiology was confirmed in 8 cases reflecting normal oropharyngeal flora. These infections were treated with antibiotics in synergistic combinations (betalactamines, quinolones, Cloramfenicol) with good results in 19 cases.
  
  
  CONCLUSIONS
  Infections of the oral cavity are an important morbidity problem due to their frequency, their pluribacterial origin as well as their potential severe evolution, especially in immunodepressed patients.
authors.affiliation: Universităţii de Medicină şi Farmacie Gr.T. Popa Iaşi, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină.
authors.forename: Florentina
authors.initials: F
authors.lastname: Vasilache
authors.forename: Carmen
authors.initials: C
authors.lastname: Dorobăţ
authors.forename: Norina Consuela
authors.initials: NC
authors.lastname: Forna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004322:Drainage; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005491:Focal Infection, Dental / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents