Isolation of pandamarilactonine-H from the roots of Pandanus amaryllifolius and synthesis of epi-pandamarilactonine-H.
A new alkaloid (1a), named pandamarilactonine-H, which possesses a methyl-2-(pyrrolidin-2-yl)acetate function, was isolated from the roots of Pandanus amaryllifolius. Eleven known alkaloids were also isolated. Unambiguous assignment of the structure of 1a, including the absolute configuration, was accomplished by spectroscopic analysis and total synthesis of its enantiomer.
Tan
Mario A
MA
Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Kitajima
Mariko
M
Kogure
Noriyuki
N
Nonato
Maribel G
MG
Takayama
Hiromitsu
H
D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031673:Pandanaceae / Q000737:chemistry*; D010679:Philippines; D018517:Plant Roots / Q000737:chemistry; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
D000470:Alkaloids; D007783:Lactones; D011759:Pyrrolidines; C552232:pandamarilactonine-H