title: The surgical management of metastatic epidural compression of the spinal cord.
abstract: Metastatic epidural compression of the spinal cord is a significant source of morbidity in patients with systemic cancer. With improved oncological treatment, survival in these patients is improving and metastatic cord compression is encountered increasingly often. The treatment is mostly palliative. Surgical management involves early circumferential decompression of the cord with concomitant stabilisation of the spine. Patients with radiosensitive tumours without cord compression benefit from radiotherapy. Spinal stereotactic radiosurgery and minimally invasive techniques, such as vertebroplasty and kyphoplasty, with or without radiofrequency ablation, are promising options for treatment and are beginning to be used in selected patients with spinal metastases. In this paper we review the surgical management of patients with metastatic epidural spinal cord compression.
authors.affiliation: Centre for Spine Studies and Surgery, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK. nasquraishi@hotmail.com
authors.forename: N A
authors.initials: NA
authors.lastname: Quraishi
authors.forename: Z L
authors.initials: ZL
authors.lastname: Gokaslan
authors.forename: S
authors.initials: S
authors.lastname: Boriani
mesh_terms: D000465:Algorithms; D003131:Combined Modality Therapy; D019299:Decompression, Surgical / Q000379:methods; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D010166:Palliative Care / Q000379:methods; D016634:Radiosurgery / Q000379:methods; D013117:Spinal Cord Compression / Q000209:etiology / Q000601:surgery*; D013125:Spinal Neoplasms / Q000150:complications / Q000556:secondary* / Q000628:therapy
chemical_list: D005938:Glucocorticoids