Paediatric Hashimoto encephalopathy, refractory epilepsy and immunoglobulin treatment - unusual case report and review of the literature.
BACKGROUND
Hashimoto encephalopathy (HE) is a rare autoimmune disorder. It is defined as a 'corticosteroid-responsive encephalopathy associated with thyroiditis'.


METHODS
We describe a boy who suffered from HE, responded only to intravenous immunoglobulin therapy. This is the first case report of immunoglobulin therapy in paediatric HE.


CONCLUSIONS
After review of the literature, we recommend that unexplained encephalopathy in children should lead to evaluation of thyroid autoantibody titres. Immunoglobulins should be considered.
Berger
I
I
The Neuro-Pediatric Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. itberg@hadassah.org.il
Castiel
Y
Y
Dor
T
T
D002648:Child; D004660:Encephalitis / Q000150:complications / Q000628:therapy*; D004827:Epilepsy / Q000209:etiology; D050031:Hashimoto Disease / Q000150:complications / Q000628:therapy*; D006801:Humans; D007116:Immunization, Passive; D016756:Immunoglobulins, Intravenous; D008297:Male; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous