title: [A case of hemophagocytic syndrome in an ulcerative colitis patient].
abstract: A case of hemophagocytic syndrome associated with ulcerative colitis is very rare. A 32-year-old man visited the hospital complaining of fever and severe abdominal pain for 7 days. He was diagnosed to have ulcerative colitis 2 years ago and had been treated with sulfasalazine. Three months ago, he had abdominal pain, weight loss, and hematochezia, so prednisolone and mercaptopurine were added to the treatment. On admission, the physical examination showed splenomegaly. Peripheral blood counts revealed pancytopenia, and bone marrow aspirate smears showed many histiocytes with active hemophagocytosis. There was no evidence of viral and bacterial infections and other neoplasms, which were commonly associated with hemophagocytic syndrome. He was successfully treated with high dose steroid. We report this case along with a review of the related literatures.
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Yong Cheol
authors.initials: YC
authors.lastname: Kim
authors.forename: Gun Min
authors.initials: GM
authors.lastname: Kim
authors.forename: Ho Sang
authors.initials: HS
authors.lastname: Lee
authors.forename: Seok In
authors.initials: SI
authors.lastname: Hong
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Cheung
authors.forename: Jin Il
authors.initials: JI
authors.lastname: Kim
authors.forename: Soo-Heon
authors.initials: SH
authors.lastname: Park
authors.forename: Jae Kwang
authors.initials: JK
authors.lastname: Kim
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001854:Bone Marrow Cells / Q000473:pathology; D003093:Colitis, Ulcerative / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003113:Colonoscopy; D003907:Dexamethasone / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D012460:Sulfasalazine / Q000627:therapeutic use; D013577:Syndrome; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D012460:Sulfasalazine; D003907:Dexamethasone; D011239:Prednisolone; D015122:Mercaptopurine