title: [A case of asymptomatic Brugada syndrome with type 1 ECG pattern and cardiac arrest: an evaluation of the prognostic value of electrophysiologic study].
abstract: Brugada syndrome is characterized by ST-segment elevation in the leads V1-3 of electrocardiography (ECG) in the absence of a structural heart disease. A 26-year old male patient was admitted with sudden cardiac arrest. Cardiopulmonary resuscitation was successful and he was referred to the reanimation unit due to unconsciousness. A year before, he was diagnosed as having Brugada syndrome with type 1 ECG pattern at another center, at which time electrophysiologic study (EPS) was not performed due to lack of symptoms and a family history of sudden cardiac death. In addition, family screening revealed two asymptomatic brothers having Brugada syndrome with type 1 ECG pattern. Medical follow-up was recommended to one of them. The other sibling underwent EPS at a different center where ventricular fibrillation was induced. An implantable cardioverter defibrillator (ICD) was recommended, but the patient refused. A further analysis of the family made at our center showed type 2 ECG changes in the father and in one of the cousins. Due to the development of persistent brain injury and an expected survival of less than a year, an ICD was not considered in the patient. The prognostic value of EPS is still controversial in asymptomatic patients with type 1 Brugada syndrome, without a family history of sudden cardiac death.
authors.affiliation: Ankara Numune Eğitim ve Araştirma Hastanesi Kardiyoloji Kliniği, Ankara, Turkey. mdmustafacetin@yahoo.com
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.forename: Alper
authors.initials: A
authors.lastname: Canbay
authors.forename: Zehra Güven
authors.initials: ZG
authors.lastname: Cetin
authors.forename: Erdem
authors.initials: E
authors.lastname: Diker
mesh_terms: D000328:Adult; D053840:Brugada Syndrome / Q000503:physiopathology*; D004562:Electrocardiography; D004594:Electrophysiology / Q000379:methods; D006323:Heart Arrest; D006801:Humans; D008297:Male; D011379:Prognosis