title: In vitro and in vivo studies of single-walled carbon nanohorns with encapsulated metallofullerenes and exohedrally functionalized quantum dots.
abstract: Single-walled carbon nanohorns (SWNHs) are new carbonaceous materials. In this paper, we report the first successful preparation of SWNHs encapsulating trimetallic nitride template endohedral metallofullerenes (TNT-EMFs). The resultant materials were functionalized by a high-speed vibration milling method and conjugated with CdSe/ZnS quantum dots (QDs). The successful encapsulation of TNT-EMFs and external functionalization with QDs provide a dual diagnostic platform for in vitro and in vivo biomedical applications of these new carbonaceous materials.
authors.affiliation: Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24060, USA.
authors.forename: Jianfei
authors.initials: J
authors.lastname: Zhang
authors.forename: Jiechao
authors.initials: J
authors.lastname: Ge
authors.forename: Michael D
authors.initials: MD
authors.lastname: Shultz
authors.forename: Eunna
authors.initials: E
authors.lastname: Chung
authors.forename: Gurpreet
authors.initials: G
authors.lastname: Singh
authors.forename: Chunying
authors.initials: C
authors.lastname: Shu
authors.forename: Panos P
authors.initials: PP
authors.lastname: Fatouros
authors.forename: Scott C
authors.initials: SC
authors.lastname: Henderson
authors.forename: Frank D
authors.initials: FD
authors.lastname: Corwin
authors.forename: David B
authors.initials: DB
authors.lastname: Geohegan
authors.forename: Alex A
authors.initials: AA
authors.lastname: Puretzky
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Rouleau
authors.forename: Karren
authors.initials: K
authors.lastname: More
authors.forename: Christopher
authors.initials: C
authors.lastname: Rylander
authors.forename: Marissa Nichole
authors.initials: MN
authors.lastname: Rylander
authors.forename: Harry W
authors.initials: HW
authors.lastname: Gibson
authors.forename: Harry C
authors.initials: HC
authors.lastname: Dorn
mesh_terms: D037741:Fullerenes / Q000737:chemistry*; D066298:In Vitro Techniques; D008670:Metals / Q000737:chemistry*; D037742:Nanotubes, Carbon; D045663:Quantum Dots
chemical_list: D037741:Fullerenes; D008670:Metals; D037742:Nanotubes, Carbon