title: Myocardial perfusion SPECT and dobutamine stress tissue Doppler imaging in evaluation of patients with stable angina pectoris.
abstract: OBJECTIVE
  To evaluate longitudinal function of ischemic and nonischemic myocardial tissue detected by Tc-99m MIBI single photon emission computed tomography (SPECT) prior to coronary revascularization in patients with stable angina pectoris.
  
  
  METHODS
  We studied 24 consecutive patients (mean age 62+/-9 years; 5 women) with stable angina pectoris. All patients underwent myocardial perfusion SPECT. Tissue Doppler imaging (TDI) was performed to detect myocardial systolic velocities of anterior, inferior, septum and lateral walls at rest and peak dobutamine stress.
  
  
  RESULTS
  A total of 96 segments were visualized with SPECT study. Maximum mean septal, lateral, anterior and inferior TDI systolic velocities were similar in ischemic and nonischemic segments (6.73+/-1.04 cm/sec, 6.93+/-1.34 cm/sec, respectively) at rest. At peak stress, maximum mean TDI systolic velocities were lower in the 37 ischemic segments (11.00+/-2.03 cm/sec) than 59 nonischemic segments (13.76+/-1.97 cm/sec, p = 0.001). Because we detected ischemia in whole group using both diagnostic tests, coronary angiography was decided. Critical coronary artery stenosis related to ischemic segments was detected and coronary revascularization decided.
  
  
  CONCLUSIONS
  TDI with dobutamine stress can be used in patients with stable angina pectoris. In this study, we observed that quantitative data by TDI associated with SPECT showed an agreement for coronary revascularization.
authors.affiliation: Department of Nuclear Medicine, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey. hulyapeker@yahoo.com
authors.forename: Hülya
authors.initials: H
authors.lastname: Yalçin
authors.forename: Ayşe
authors.initials: A
authors.lastname: Aktaş
authors.forename: Tansel
authors.initials: T
authors.lastname: Erol
authors.forename: Ali Fuat
authors.initials: AF
authors.lastname: Yapar
authors.forename: Mehmet
authors.initials: M
authors.lastname: Aydin
authors.forename: Nazan
authors.initials: N
authors.lastname: Savaş
authors.forename: Fatih
authors.initials: F
authors.lastname: Yalçin
authors.forename: Haldun
authors.initials: H
authors.lastname: Müderrisoğlu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000000981:diagnostic imaging* / Q000601:surgery; D004280:Dobutamine; D004452:Echocardiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging; D009204:Myocardial Revascularization; D011859:Radiography; D013599:Systole / Q000502:physiology; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D018608:Ultrasonography, Doppler; D016277:Ventricular Function, Left
chemical_list: D004280:Dobutamine; D017256:Technetium Tc 99m Sestamibi