title: Bilateral laryngoceles in association with squamos cell carcinoma: a case report and literature review.
abstract: Coexistence of laryngoceles and laryngeal carcinoma is still being debated, and there are several suggested theories about the pathophysiological relationship between these two entities. We present the case of a 66-year-old male patient with bilateral laryngomucoceles and laryngeal squamos cell carcinoma. A systematic hystological examination of whole organ sections showed that the submucosal spreading of cancer around the saccular necks on both sides caused stenosis which probably created a one-way valve mechanism allowing air to enter the saccule but not to exit. Progression of the tumor completely obstructed the laryngeal opening, leading to glandular secretion stagnation and formation of laryngomucoceles.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Osijek University Hospital Center, Osijek, Croatia. rosso.marinela@kbo.hr
authors.forename: Marinela
authors.initials: M
authors.lastname: Rosso
authors.forename: Ksenija
authors.initials: K
authors.lastname: Marjanović
authors.forename: Josip
authors.initials: J
authors.lastname: Males
authors.forename: Tatjana
authors.initials: T
authors.lastname: Sepić
authors.forename: Igor
authors.initials: I
authors.lastname: Segec
authors.forename: Mićo
authors.initials: M
authors.lastname: Rosso
authors.forename: Dubravko
authors.initials: D
authors.lastname: Manestar
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007818:Laryngeal Diseases / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D011859:Radiography; D016896:Treatment Outcome