title: Imaging mouse development with confocal time-lapse microscopy.
abstract: The gene expression, signaling, and cellular dynamics driving mouse embryo development have emerged through embryology and genetic studies. However, since mouse development is a temporally regulated three-dimensional process, any insight needs to be placed in this context of real-time visualization. Live imaging using genetically encoded fluorescent protein reporters is pushing the envelope of our understanding by uncovering unprecedented insights into mouse development and leading to the formulation of quantitative accurate models.
authors.affiliation: Developmental Biology Program, Sloan-Kettering Institute, New York, USA.
authors.forename: Sonja
authors.initials: S
authors.lastname: Nowotschin
authors.forename: Anna
authors.initials: A
authors.lastname: Ferrer-Vaquer
authors.forename: Anna-Katerina
authors.initials: AK
authors.lastname: Hadjantonakis
mesh_terms: D000818:Animals; D003470:Culture Media / Q000737:chemistry; D046149:Embryo Culture Techniques / Q000295:instrumentation / Q000379:methods*; D004622:Embryo, Mammalian / Q000166:cytology* / Q000502:physiology*; D047108:Embryonic Development; D005260:Female; D005456:Fluorescent Dyes / Q000378:metabolism*; D008297:Male; D051379:Mice; D018613:Microscopy, Confocal / Q000295:instrumentation / Q000379:methods; D011247:Pregnancy; D051381:Rats; D013194:Staining and Labeling / Q000379:methods; D013997:Time Factors
chemical_list: D003470:Culture Media; D005456:Fluorescent Dyes