title: Haemophilus influenzae outer membrane protein P6 molecular characterization may not differentiate all strains of H. Influenzae from H. haemolyticus.
abstract: Distinguishing nontypeable Haemophilus influenzae and Haemophilus haemolyticus isolates by outer membrane protein (OMP) P6 gene sequencing is complicated by sequence variants in isolates. Further testing using RapID NH and multilocus sequence analysis may not help identify some isolates. Translated OMP P6 gene sequences are not conserved among all isolates presumed to be H. influenzae.
authors.affiliation: Rochester General Hospital, Rochester General Research Institute, Center for Infectious Diseases and Immunology, Rochester, NY 14621, USA.
authors.forename: Arthur
authors.initials: A
authors.lastname: Chang
authors.forename: Diana G
authors.initials: DG
authors.lastname: Adlowitz
authors.forename: Edna
authors.initials: E
authors.lastname: Yellamatty
authors.forename: Michael
authors.initials: M
authors.lastname: Pichichero
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001431:Bacteriological Techniques / Q000379:methods*; D002675:Child, Preschool; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D014644:Genetic Variation; D006190:Haemophilus / Q000145:classification* / Q000235:genetics*; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000382:microbiology; D018073:Haemophilus Vaccines / Q000235:genetics*; D006801:Humans; D007223:Infant; D012680:Sensitivity and Specificity; D017422:Sequence Analysis, DNA
chemical_list: D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial; D018073:Haemophilus Vaccines; C069990:P6 outer membrane protein, Haemophilus