TCS in monogenic forms of Parkinson's disease.
During the last decade, mutations in a growing number of genes have been found to cause monogenic forms of Parkinson's disease (PD). Moreover, many studies shed light on their contribution to sporadic variants of PD. Since hyperechogenicity of the substantia nigra (SN) represents a characteristic hallmark of sporadic PD questions arise concerning the echo pattern of monogenic forms of this disorder on TCS.
Brockmann
Kathrin
K
Department of Neurodegeneration, Hertie Institute of Clinical Brain Research and German Center of Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Hagenah
Johann
J
D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D009154:Mutation / Q000235:genetics; D010300:Parkinson Disease / Q000000981:diagnostic imaging* / Q000235:genetics* / Q000473:pathology; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods* / Q000592:standards