title: Chromatographic analysis of local anesthetics in biological samples.
abstract: This paper reviews gas and liquid chromatographic methods for screening, identification and quantification of local anesthetics and/or their metabolites in biological samples. Basic information about sample preparation, separation, detection, and quantification of each procedure is summarised. The pros and cons of the various procedures are critically discussed.
authors.affiliation: University of Medicine and Pharmacy, Faculty of Pharmacy, Petru Rares, 4, 200349, Craiova, Romania. mihaelabaniceru@yahoo.com
authors.forename: Mihaela
authors.initials: M
authors.lastname: Baniceru
authors.forename: Costel Valentin
authors.initials: CV
authors.lastname: Manda
authors.forename: Sanda Mihaela
authors.initials: SM
authors.lastname: Popescu
mesh_terms: D000779:Anesthetics, Local / Q000032:analysis / Q000097:blood / Q000494:pharmacology* / Q000652:urine; D002623:Chemistry Techniques, Analytical; D002624:Chemistry, Clinical / Q000379:methods; D002849:Chromatography, Gas / Q000379:methods*; D002853:Chromatography, Liquid / Q000379:methods*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013058:Mass Spectrometry / Q000379:methods*; D008956:Models, Chemical; D052617:Solid Phase Microextraction
chemical_list: D000779:Anesthetics, Local