Bromoderma in a patient with migrating partial seizures in infancy.
A 5-month-old boy with migrating partial seizures in infancy acquired bromoderma 4 weeks after initiating potassium bromide (KBr) therapy (60mg/kg/day). Erythematous pustules appeared on the forehead within a few days of attaching electroencephalography electrodes, and on the cheek at the site of nasogastric tube fixation. These later developed into vegetant plaques. Bromoderma aggravated at the site of skin biopsy that was performed 4 weeks after KBr termination. Bromoderma tuberosum should be recognized widely, considering the increasing use of KBr for treating intractable childhood epilepsy.
Nabatame
Shin
S
Department of Child Neurology, National Center Hospital (NCH), National Center of Neurology and Psychiatry (NCNP), 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo 187-8551, Japan.
Saito
Yoshiaki
Y
Sakuma
Hiroshi
H
Komaki
Hirofumi
H
Nakagawa
Eiji
E
Sugai
Kenji
K
Sasaki
Masayuki
M
Uchiyama
Kentaro
K
Kosaka
Maki
M
D001965:Bromides / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D003875:Drug Eruptions / Q000175:diagnosis / Q000473:pathology; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D017680:Potassium Compounds / Q000009:adverse effects*; D012640:Seizures / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
D001965:Bromides; D017680:Potassium Compounds; C039004:potassium bromide