title: Drug-induced liver disease.
abstract: More than 1000 drugs have been associated with hepatic injury, which can present in all forms of acute and chronic liver disease. The identification and prevention of drug-induced liver disease remain challenging tasks for health care professionals as reliable and practical assessment tools are not currently available to diagnose drug-induced liver disease. The management of drug-induced liver injury is generally supportive, and the recognition and avoidance of causative agents remain the most effective strategy for positive clinical outcomes.
authors.affiliation: Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, University of Southern California School of Pharmacy, USC University Hospital, 1500 San Pablo Street, Los Angeles, CA 90033, USA. jiwonkim@usc.edu
authors.forename: Jiwon W
authors.initials: JW
authors.lastname: Kim
authors.forename: Akiko
authors.initials: A
authors.lastname: Hattori
authors.forename: Paula V
authors.initials: PV
authors.lastname: Phongsamran
mesh_terms: D000208:Acute Disease; D056486:Chemical and Drug Induced Liver Injury / Q000145:classification / Q000453:epidemiology / Q000209:etiology / Q000451:nursing / Q000503:physiopathology*; D002779:Cholestasis / Q000139:chemically induced; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology; D019587:Dietary Supplements; D018450:Disease Progression; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology; D008111:Liver Function Tests; D012307:Risk Factors
chemical_list: D003577:Cytochrome P-450 Enzyme System