Tuning hydrogel properties and function using substituent effects.
The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-tri-azaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.
Kohman
Richie E
RE
Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL, 61801, USA.
Cha
Chaenyung
C
Zimmerman
Steven C
SC
Kong
Hyunjoon
H