title: Health-related quality of life in patients with cryptogenic polyneuropathy compared with the general population.
abstract: OBJECTIVE
  To evaluate the quality of life (QOL) in patients with cryptogenic polyneuropathy.
  
  
  METHODS
  Two validated instruments (SF-36 and EQ-5D) were sent to 86 patients with a 72% response rate (44 men, 18 women). As reference, 2721 individuals (1292 men, 1429 women; 59% response rate) from the general population responded to the same QOL instruments.
  
  
  RESULTS
  Compared to the general population, QOL was significantly more affected in patients with polyneuropathy concerning motor functions, with 42% of the patients reporting problems with walking, 7% having difficulties with washing and dressing, and 31% having problems with usual activities (work, study, household work, and family or leisure activities). The EQ-5D results showed that 85% of the patients were suffering from pain compared to 56% of the general population. Mental health was preserved among patients with polyneuropathy. Mobility was declining with increasing age in patients, but was not affected by disease duration.
  
  
  CONCLUSIONS
  Our study showed that patients with cryptogenic polyneuropathy have a lower QOL compared to the general population, although mental health scores did not differ between the groups. This information may be helpful when explaining the disease and its impact on newly diagnosed patients.
authors.affiliation: Section of Neurology, Department of Internal Medicine, Ryhov County Hospital, Jönköping, Sweden. jonas.lindh@lj.se
authors.forename: Jonas
authors.initials: J
authors.lastname: Lindh
authors.forename: Martin
authors.initials: M
authors.lastname: Tondel
authors.forename: Bodil
authors.initials: B
authors.lastname: Persson
authors.forename: Magnus
authors.initials: M
authors.lastname: Vrethem
mesh_terms: D000203:Activities of Daily Living; D000222:Adaptation, Physiological; D000223:Adaptation, Psychological; D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D026741:Physical Therapy Modalities; D011115:Polyneuropathies / Q000175:diagnosis* / Q000523:psychology / Q000534:rehabilitation*; D011788:Quality of Life; D012016:Reference Values; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D013548:Sweden