Abdominal nodal localization of Castleman's disease: report of a case.
BACKGROUND
Castleman's disease (CD) is a rare benign disorder that may grow in any area where lymphoid tissue is normally present but the most frequent site is mediastinum (67%); the abdomen is rarely affected by this pathology. In the pathogenesis of CD an important role could be played by HHV-8. Diagnosis is difficult and the diagnostic certainty is obtained only by histological examination. For this disease there is no gold-standard treatment.


METHODS
We report the case of a woman of 33 years of age affected by a rare form of abdominal nodal localization of Castleman's Disease for which the patient underwent surgery.


CONCLUSIONS
CD must be included in the differential diagnosis of retroperitoneal tumors even though the definitive diagnosis can only be achieved by histological and immunohistochemical examination. In the case of single location, the treatment of choice is surgical removal.
Greco
L G
LG
Department of Emergency and Organ Transplantation, Section of General Surgery and Liver Transplantation, University of Bari, Italy.
Tedeschi
M
M
Stasolla
S
S
Gentile
A
A
Gentile
A
A
Piscitelli
D
D
D000005:Abdomen; D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000906:Antibodies / Q000097:blood; D005871:Castleman Disease / Q000175:diagnosis* / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D019288:Herpesvirus 8, Human / Q000276:immunology; D006801:Humans; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis; D015431:Weight Loss
D000906:Antibodies