title: [Risk factors for visual outcome after bleb-related infection].
abstract: OBJECTIVE
  To investigate risk factors for visual impairment following bleb-related infection after trabeculectomy with mitomycin C.
  
  
  METHODS
  We retrospectively reviewed 31 cases of bleb-related infection at Osaka Koseinenkin hospital from 2004 to 2007.
  
  
  RESULTS
  Twelve cases of blebitis and 19 cases of bleb-related endophthalmitis were studied. According to the stage of infection, each patient was continued to be treated following a previously decided treatment strategy. Fifteen patients underwent pars plana vitrctomy. Two patients with blebitis progressed to endopthalmitis. Visual acuity in seven eyes (22.6%) decreased by two or more lines following infection. Risk factors for visual impairments following bleb-related infections were recurrence of infection (p = 0.022), negative Seidel tests (p = 0.0056), aphakia (p = 0.045), avitreous (p = 0.00070), positive Streptococcus species (p = 0.029), and prolonged inflammation (p = 0.014).
  
  
  CONCLUSIONS
  Recurrence of infection, negative Seidel tests, aphakia and avitreous are risk factors for visual impairment following bleb-related infection after trabeculectomy.
authors.affiliation: Department of Ophthalmology, Hoshigaoka Koseinenkin Hospital, 4-8-1 Hoshigaoka, Hirakata-shi 573-8511, Japan. atti-osk@umin.ac.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Our
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Kano
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Kuwayama
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001768:Blister / Q000150:complications / Q000628:therapy*; D009877:Endophthalmitis / Q000209:etiology; D015818:Eye Infections, Bacterial / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D014130:Trabeculectomy; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity