Wegener's granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibroblastic tumour: a case report.
OBJECTIVE
To compare two potential diagnoses of a temporal bone pseudotumour: an inflammatory myofibroblastic tumour and Wegener's granulomatosis.


METHODS
A case of Wegener's granulomatosis that mimicked an inflammatory myofibroblastic tumour is reported. The clinical presentation, staging of the disease, histology, and follow-up are analysed.


RESULTS
Histopathology of the temporal bone failed to provide an accurate diagnosis, even after immunocytochemical analyses. The diagnosis of Wegener's granulomatosis was suspected after biopsy of a pulmonary mass and was confirmed by the presence of anti-neutrophil cytoplasmic antibodies in blood samples.


CONCLUSIONS
Irrespective of the aetiology, a pseudotumour of the temporal bone should always be investigated by biology and radiology. Radiological investigations will allow staging of the disease and specific localisation for biopsies.
Carpentier
A-S
AS
Department of Otorhinolaryngology, CHU Hautepierre, Strasbourg, France.
Riehm
S
S
Charpiot
A
A
Onea
A
A
Debry
C
C
Schultz
P
P
D000328:Adult; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006801:Humans; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis / Q000503:physiopathology; D019291:Skull Base; D013701:Temporal Bone