title: [Correlation between pre-treatment anemia and prognosis in non-small cell lung cancer patients].
abstract: OBJECTIVE
  The patients with non-small cell lung cancer (NSCLC) might contract anemia, however, whether anemia is one of the independent prognostic factors to the patients with NSCLC is still controversial. So the aim of this study is to investigate the correlation between anemia and overall survival (OS) in patients with NSCLC.
  
  
  METHODS
  1 018 patients with operable NSCLC were retrospectively analyzed in our hospital from January 2000 to December 2008.
  
  
  RESULTS
  The occurrence of anemia before operation was 252/1 018 (24.1%). The OS in NSCLC patients without anemia was (2 425.98 +/- 50.03) days, and the OS in patients with anemia was (2 107.15 +/-93.86) days. There was significant difference in the OS between them (P = 0.001). The patients with anemia in stage I had shorter survival time than those without anemia (P < 0.001). But there was no difference in other stage patients. TNM stage, gender, tumor size and lymph nodes metastasis were correlated with OS using Cox regression analysis.
  
  
  CONCLUSIONS
  Anemia is correlated with survival in operable NSCLC patients. Moreover, it is an independent prognostic factor in NSCLC patients with stage I.
authors.affiliation: Institute of Respiratory Diseases,First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China.
authors.forename: Qiuhua
authors.initials: Q
authors.lastname: Deng
authors.forename: Haihong
authors.initials: H
authors.lastname: Yang
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
authors.forename: Hanzhang
authors.initials: H
authors.lastname: Chen
authors.forename: Yuan
authors.initials: Y
authors.lastname: Qiu
authors.forename: Danping
authors.initials: D
authors.lastname: Wen
authors.forename: Xinguo
authors.initials: X
authors.lastname: Xiong
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Jianxing
authors.initials: J
authors.lastname: He
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000150:complications*; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000706:statistics & numerical data; D011379:Prognosis; D016016:Proportional Hazards Models