title: Long-term complications and survival of patients after orthotopic liver transplantation.
abstract: BACKGROUND
  The survival rates among patients after orthotopic liver transplantation (OLT) has increased to 83% and 75% at 1 and 5 years, respectively. However, these patients are at increased risk of long-term complications.
  
  
  OBJECTIVE
  To identify long-term complications and survivals among patients after OLT.
  
  
  METHODS
  From September 1999 to July 2009 we evaluated long-term complications among 78 consecutive patients after OLT including 46 males.
  
  
  RESULTS
  Complications de novo after OLT were metabolic (n = 38; 67%), infections (n = 13; 23%), recurrent liver disease (n = 12; 21%), osteopenia/osteoporosis (n = 10; 18%), acute/chronic rejection (n = 8; 14%), renal failure (n = 2; 4%) and Kaposi's sarcoma (n = 1). Their overall survival at 118 months was 55%.
  
  
  CONCLUSIONS
  The most common long-term complications after OLT were metabolic, infections, and disease recurrence.
authors.affiliation: Liver Unit, Dr. José Eleuterio González University Hospital, UANL, Monterrey, NL, México. linda_uanl@hotmail.com
authors.forename: L E
authors.initials: LE
authors.lastname: Muñoz
authors.forename: H
authors.initials: H
authors.lastname: Nañez
authors.forename: F
authors.initials: F
authors.lastname: Rositas
authors.forename: E
authors.initials: E
authors.lastname: Pérez
authors.forename: S
authors.initials: S
authors.lastname: Razo
authors.forename: P
authors.initials: P
authors.lastname: Cordero
authors.forename: L
authors.initials: L
authors.lastname: Torres
authors.forename: H
authors.initials: H
authors.lastname: Zapata
authors.forename: M A
authors.initials: MA
authors.lastname: Hernández
authors.forename: M M
authors.initials: MM
authors.lastname: Escobedo
mesh_terms: D001851:Bone Diseases, Metabolic / Q000453:epidemiology; D006528:Carcinoma, Hepatocellular / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology; D006526:Hepatitis C / Q000601:surgery; D006801:Humans; D007239:Infections / Q000453:epidemiology; D008107:Liver Diseases / Q000145:classification* / Q000453:epidemiology / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects* / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology; D011183:Postoperative Complications / Q000145:classification / Q000453:epidemiology*; D012008:Recurrence; D051437:Renal Insufficiency / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors