A new oxidative stress marker in patients with nasal polyposis: advanced oxidation protein products (AOPP).
OBJECTIVE
The aim of this study was to determine whether levels of advanced oxidation protein products (AOPP) can be used a marker of oxidative stress in the etiology of nasal polyposis.


METHODS
Twenty-four patients diagnosed with nasal polyposis in Haseki Education and Research Hospital ENT Department between March and June 2008 were included in the study. The AOPP serum levels in NP patients and 24 healthy controls were measured with spectrophotometry and the results were compared statistically.


RESULTS
AOPP levels were significantly higher in the study group compared with the control group.


CONCLUSIONS
Our findings suggest that AOPP levels can be used as a marker of oxidative stress in patients with nasal polyposis. Future studies are neccessary to evaluate the efficacy of antioxidant therapy.
Veyseller
B
B
Department of Otorhinolaryngology and Head and Neck Surgery, Istanbul, Turkey.
Aksoy
E
E
Ertaş
B
B
Keskin
M
M
Ozturan
O
O
Yildirim
Y S
YS
Bayraktar
E G I
EG
Oztürk
H
H
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism
D015415:Biomarkers; D001798:Blood Proteins; D017382:Reactive Oxygen Species