Masson's vegetant hemangioendothelioma arising in the uterine cervix during pregnancy: a case report.
BACKGROUND
Hemangioendothelioma is a rare benign intravascular tumor that can be confused with other vascular neoplasms. We report the first case of cervical vegetant intravascular hemangioendothelioma (Masson's tumor) arising in a pregnant woman.


METHODS
A 40-year-old woman at 15 weeks' gestation developed a voluminous cervical mass and vaginal bleeding. We excised the lesion during pregnancy because of its rapid growth, bleeding, and severe pain. The pathological diagnosis was Masson's tumor or intravascular papillary endothelial hyperplasia. The tumor showed strong estrogen and progesterone receptor expression.The patient underwent an elective cesarean section at term, giving birth to a healthy baby. Clinical follow-up at 3 years showed no complications or recurrence.


CONCLUSIONS
Obstetricians should be aware that Masson's tumor may occasionally arise in the uterine cervix during pregnancy. This benign vascular tumor may display a rapid growth because of the presence of sex steroid receptors. Differential diagnosis should consider a malignant vascular tumor, including Kaposi's sarcoma and angiosarcoma. Surgical removal should not be postponed because of pain and bleeding. Fetal and maternal outcomes were favorable.
Susini
Tommaso
T
Sciences for Women's and Newborns' Health Department, University of Florence, Florence, Italy. tommaso.susini@unifi.it
Molino
Cecilia
C
Castiglione
Francesca
F
Olivieri
Simone
S
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D011262:Pregnancy Trimester, Second; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery