A Langmuir approach using on monolayer interactions to investigate surface active peptides.
The Langmuir Blodgett apparatus provides a versatile system for studying the interfacial properties of peptides and peptide-membrane interactions under controlled conditions. Using amphiphilic α-helical peptides to highlight studies undertaken, here we discuss the use of this system to provide information on the surface activity of peptides and describe the insights these studies give into biological function.
Dennison
Sarah R
SR
School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Harris
Frederick
F
Phoenix
David A
DA
D000595:Amino Acid Sequence; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry* / Q000378:metabolism; D008563:Membrane Lipids / Q000737:chemistry* / Q000378:metabolism; D008567:Membranes, Artificial; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011312:Pressure; D013499:Surface Properties; D013816:Thermodynamics
D023181:Antimicrobial Cationic Peptides; D008563:Membrane Lipids; D008567:Membranes, Artificial