Aptamer based reversible DNA induced hydrogel system for molecular recognition and separation.
An aptamer-based DNA strand, captured with a specific molecule from a multi-species system, was used to initiate crosslinking of the hydrogel. The hydrogel can then be dissolved with a displacement of the DNA strand and the captured molecule can be released. Recognition and separation at the molecular level is thus achieved.
He
Xiaojin
X
Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear water bay, Kowloon, Hong Kong.
Wei
Bryan
B
Mi
Yongli
Y
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*
D052157:Aptamers, Nucleotide; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D004247:DNA