Epithelial pathways in choroid plexus electrolyte transport.
A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.
Damkier
Helle H
HH
Department of Anatomy and the Water and Salt Research Center, Aarhus University, Aarhus C, Denmark.
Brown
Peter D
PD
Praetorius
Jeppe
J
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D002555:Cerebrospinal Fluid / Q000378:metabolism; D018118:Chloride Channels / Q000378:metabolism; D002831:Choroid Plexus / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D004848:Epithelium / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D015221:Potassium Channels / Q000378:metabolism; D015222:Sodium Channels / Q000502:physiology; D014867:Water / Q000378:metabolism
D001639:Bicarbonates; D002352:Carrier Proteins; D018118:Chloride Channels; D015221:Potassium Channels; D015222:Sodium Channels; D014867:Water