title: Dual kidney transplantation: case report.
abstract: Chronic shortage of kidney transplants worldwide has led to the use of organs from so called marginal or borderline donors, now termed "expanded-criteria donors". There has been an emerging practice of dual kidney transplantation (DKT) to compensate for sub optimal nephron mass of such kidneys. We performed DKT in "Merkur" University Hospital in August 2005. The donor was a 72-year old female with a history of long-term hypertension, aneurysm of the posterior cerebral artery, cerebrovascular insult (CVI), and with normal creatinine values and kidney function at the time of explantation. Initial biopsy of donor kidneys revealed acute tubular damage, with connective changes in 22% and 11% of glomeruli in the left and the right kidney, respectively. The recipient was a 60-year old male diagnosed with the IgA nephropathy on the last biopsy in 1999, and on dialysis since November 2003. Postoperative course was uneventful without any surgical complications. A triple immunosuppressive protocol was used. On follow-up ultrasonography 4 years posttransplantation both kidneys appeared of normal size and parenchymal pattern and with no signs of dilatation of the canal system, and color Doppler examination demonstrated normal flow in both kidneys. In conclusion, the use of DKT ie. donors by the expanded-criteria will continue to increase, and further studies of the results will, with no doubt, support this method.
authors.affiliation: Division of Urology, "Merkur" University Hospital, Zagreb, Croatia. zeljko.vidas@zg.t-com.hr
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Vidas
authors.forename: Branislav
authors.initials: B
authors.lastname: Kocman
authors.forename: Mladen
authors.initials: M
authors.lastname: Knotek
authors.forename: Dinko
authors.initials: D
authors.lastname: Skegro
mesh_terms: D000368:Aged; D002102:Cadaver; D005260:Female; D005500:Follow-Up Studies; D005922:Glomerulonephritis, IGA / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents