Luteal phase oocyte retrieval and in vitro maturation is an optional procedure for urgent fertility preservation.
OBJECTIVE
To compare the results of in vitro maturation (IVM) of oocytes for fertility preservation performed during the luteal phase of the cycle with those of IVM performed during the follicular phase.


METHODS
Retrospective chart review (August 2007 to June 2009).


METHODS
Academic tertiary referral fertility center.


METHODS
Cancer patients who underwent treatment for fertility preservation.


METHODS
IVM treatment during either luteal or follicular phase.


METHODS
Number of oocytes, maturation and fertilization rates, and number of oocytes and embryos that were frozen.


RESULTS
Eighteen cancer patients underwent IVM fertility preservation, five in their luteal phase and 13 in their follicular phase. The baseline characteristics of both groups were similar. There were no significant differences in the number of retrieved oocytes, maturation rates, fertilization rates, or the total number of oocytes and embryos that were cryopreserved.


CONCLUSIONS
These results suggest that IVM during the luteal phase can be offered to patients as an optional treatment for urgent fertility preservation when there is insufficient time for conventional follicular phase oocyte retrieval before chemotherapy must be initiated.
Maman
Ettie
E
IVF Unit, Division of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel. ettiemaman@gmail.com
Meirow
Dror
D
Brengauz
Masha
M
Raanani
Hila
H
Dor
Jehushua
J
Hourvitz
Ariel
A
D000293:Adolescent; D000328:Adult; D001755:Blastocyst; D015925:Cryopreservation; D005260:Female; D005298:Fertility; D005307:Fertilization in Vitro / Q000379:methods*; D005498:Follicular Phase; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy*; D008183:Luteal Phase; D009369:Neoplasms / Q000150:complications*; D054315:Oocyte Retrieval / Q000379:methods*; D009865:Oocytes / Q000166:cytology; D012189:Retrospective Studies; D055815:Young Adult