Multi-modal hallucinations and cognitive function in Parkinson's disease.
OBJECTIVE
Hallucinations have been linked to a constellation of cognitive deficits in Parkinson's disease (PD), but it is not known whether multi-modal hallucinations are associated with greater neuropsychological dysfunction.


METHODS
152 idiopathic PD patients were categorized based on the presence or absence of hallucinations and then were further subdivided into visual-only (VHonly; n = 35) or multi-modal (VHplus; n = 12) hallucination groups. All participants underwent detailed neuropsychological assessment.


RESULTS
Participants with hallucinations performed more poorly on select neuropsychological measures and exhibited more mood symptoms. There were no differences between VHonly and VHplus groups.


CONCLUSIONS
PD patients with multi-modal hallucinations are not at greater risk for neuropsychological impairment than those with single-modal hallucinations.
Katzen
Heather
H
Division of Neuropsychology, Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. hkatzen@med.miami.edu
Myerson
Connie
C
Papapetropoulos
Spiridon
S
Nahab
Fatta
F
Gallo
Bruno
B
Levin
Bonnie
B
D000339:Affect / Q000502:physiology; D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use; D001288:Attention / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000150:complications* / Q000453:epidemiology / Q000523:psychology*; D046690:Deep Brain Stimulation; D004644:Emotions / Q000502:physiology; D056344:Executive Function / Q000502:physiology; D005260:Female; D006212:Hallucinations / Q000150:complications* / Q000453:epidemiology / Q000523:psychology*; D006801:Humans; D007361:Intelligence Tests; D007802:Language; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D011569:Psychiatric Status Rating Scales; D012306:Risk; D013028:Space Perception / Q000502:physiology
D000978:Antiparkinson Agents