Two new aristolochic acid derivatives from the roots of Aristolochia fangchi and their cytotoxicities.
Phytochemical investigation of 90% ethanol extracts of the roots of Aristolochia fangchi yielded two new aristolochic acid derivatives named Aristolochic Acid F and Aristolochic Acid G, together with three known compounds. Their structures were elucidated by spectral analysis. The cytotoxicity of the isolated compounds was also determined.
Cai
Yu
Y
School of Pharmacy, Jinan University, 601 West Huangpu Road, Guangzhou, China.
Cai
Tian-Ge
TG
D000818:Animals; D030022:Aristolochia / Q000737:chemistry*; D034341:Aristolochic Acids / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D008968:Molecular Conformation; D018517:Plant Roots / Q000737:chemistry*; D013237:Stereoisomerism; D013552:Swine
D034341:Aristolochic Acids; C554025:aristolochic acid F; C554023:aristolochic acid G