title: Aplastic crisis induced by human parvovirus B19 as an initial presentation of hereditary spherocytosis.
abstract: The association between aplastic crisis and human parvovirus (HPV) B19 infection has been described in patients with hereditary spherocytosis (HS). Most cases of aplastic crisis in patients with HS induced by HPV B19 have been reported in children and adolescents. In this paper, we describe an aplastic crisis induced by HPV B19 in the 34 year old female as an initial presentation of HS. Although other viral illnesses cause some decompensation in HS, the anemia is rarely as profound as seen in acute HPV B19 infections.
authors.affiliation: Department of Hematology, University Clinic of Internal Medicine, "Sestre milosrdnice" University Hospital, Zagreb, Croatia. dubravka.carzavec@zg.t-com.hr
authors.forename: Dubravka
authors.initials: D
authors.lastname: Carzavec
authors.forename: Petar
authors.initials: P
authors.lastname: Gaćina
authors.forename: Ankica
authors.initials: A
authors.lastname: Vasilj
authors.forename: Sandra Kojić
authors.initials: SK
authors.lastname: Katović
mesh_terms: D000328:Adult; D000741:Anemia, Aplastic / Q000209:etiology / Q000821:virology; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D010322:Parvoviridae Infections / Q000150:complications* / Q000175:diagnosis*; D016732:Parvovirus B19, Human; D013102:Spherocytes / Q000473:pathology; D013103:Spherocytosis, Hereditary / Q000150:complications / Q000473:pathology*