title: Nonsyndromic multiple basal cell carcinomas successfully treated with imiquimod 5% cream.
abstract: This report describes the case of a 60-year-old man with nonsyndromic multiple basal cell carcinomas that responded to imiquimod 5% cream. The patient had no additional anomalies suggesting any syndromes associated with multiple basal cell carcinomas. By applying the agent 5 times a week for 20 weeks, we obtained good clinical results, and we confirmed the improvement with histopathologic examination. We suggest that patients with multiple basal cell carcinomas should be interviewed about and tested for the associated syndromes, and topical imiquimod should be kept in mind as an alternative therapy choice in these patients.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
authors.forename: Engin
authors.initials: E
authors.lastname: Kocabaş
authors.forename: Aylin Türel
authors.initials: AT
authors.lastname: Ermertcan
authors.forename: Cemal
authors.initials: C
authors.lastname: Bilaç
authors.forename: Dilek Bayraktar
authors.initials: DB
authors.lastname: Bilaç
authors.forename: Peyker
authors.initials: P
authors.lastname: Temiz
mesh_terms: D000279:Administration, Cutaneous; D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002280:Basal Cell Carcinoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod