Loss of sympathetic nerve fibers in intestinal endometriosis.
This study analyzed by immunofluorescence staining the sympathetic innervation in the bowel adjacent to the endometriotic lesion and in the healthy tissue at the border of the resected specimen. Sympathetic nerve fibers are significantly reduced in the mucosal and muscular layer near the endometriotic lesions; in contrast, sensory nerve fiber density is not altered in the area near the endometriotic lesions.
Ferrero
Simone
S
Department of Obstetrics and Gynecology, San Martino Hospital and University of Genoa, Genoa, Italy. dr@simoneferrero.com
Haas
Stefanie
S
Remorgida
Valentino
V
Camerini
Giovanni
G
Fulcheri
Ezio
E
Ragni
Nicola
N
Straub
Rainer H
RH
Capellino
Silvia
S
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000320:Adrenergic Fibers / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001342:Autonomic Nervous System Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D016022:Case-Control Studies; D002452:Cell Count; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery; D004715:Endometriosis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D008875:Middle Aged