An improved sensitivity nonenzymatic glucose biosensor based on a CuxO modified electrode.
An enzymeless biosensor based on CuxO/Cu electrode was investigated in this study. The XRD analysis confirmed that CuxO nanostructured material was composed of Cu2O and CuO. The FESEM images showed that the catalysts were flower-like with large surface area. From cyclic voltammograms, the peak current of CuxO/Cu electrode was 6, 6.3 and 1.7 times higher than that of the Cu foil, Cu2O/GCE and CuO/GCE electrodes, respectively. The biosensor based on CuxO/Cu exhibited excellent performance for glucose detection, giving a linear dependence between current and glucose concentration (R=0.996), with a low detection limit (0.049 mM) and high sensitivity (1.62 mA cm(-2) mM(-1)). Finally, the CuxO/Cu sensor was applied and checked in the glucose determination in blood serum samples.
Li
Cuiling
C
Changchun Institute of Applied Chemistry, Graduate School of Chinese Academy of Science, 5625 Renmin Street, Changchun 130022, PR China.
Su
Yi
Y
Zhang
Senwang
S
Lv
Xiangyu
X
Xia
Hailong
H
Wang
Yujiang
Y
D015374:Biosensing Techniques / Q000295:instrumentation*; D001786:Blood Glucose / Q000032:analysis*; D003217:Conductometry / Q000295:instrumentation*; D003300:Copper / Q000737:chemistry*; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D012680:Sensitivity and Specificity
D001786:Blood Glucose; D003300:Copper; C030973:cupric oxide