title: Prediction error and myopic shift after intraocular lens implantation in paediatric cataract patients.
abstract: OBJECTIVE
  To determine the amount of myopic shift in children after cataract surgery with intraocular lens (IOL) implantation and to evaluate success in achieving the target refraction.
  
  
  METHODS
  The children were assigned into three groups depending on age at time of surgery: Group A, 0-1 years old; Group B, 1-7 years old; Group C, 7-18 years old. Multiple regression analysis was used to create a formula for expected myopic shift and to find out which variables were associated with a higher absolute prediction error.
  
  
  RESULTS
  Children less than 12 months of age experienced higher myopic shifts and a larger mean rate of refractive change per year compared with older children. We found higher myopic shifts in younger children at time of surgery and children with unilateral cataract. Absolute prediction error was significantly higher in Group A compared with Groups B and C (p=0.022 and p=0.037, respectively). Multiple regression analysis showed that corneal radius was the only variable significantly associated with absolute prediction error.
  
  
  CONCLUSIONS
  Our data demonstrate the complexity in predicting the postoperative refraction in children under 1 year old and show that age at surgery and laterality are factors to consider when deciding which IOL power to implant in children.
authors.affiliation: Erasmus University Medical Center, Department of Ophthalmology, 3000-CA Rotterdam, The Netherlands.
authors.forename: N E D
authors.initials: NE
authors.lastname: Hoevenaars
authors.forename: J R
authors.initials: JR
authors.lastname: Polling
authors.forename: R C W
authors.initials: RC
authors.lastname: Wolfs
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D001036:Aphakia, Postcataract / Q000453:epidemiology; D002387:Cataract Extraction / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D005123:Eye / Q000254:growth & development*; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000175:diagnosis / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D019654:Lens Implantation, Intraocular / Q000379:methods / Q000706:statistics & numerical data*; D007910:Lenses, Intraocular / Q000706:statistics & numerical data*; D008297:Male; D009216:Myopia / Q000175:diagnosis* / Q000453:epidemiology; D011237:Predictive Value of Tests; D012030:Refractive Errors / Q000175:diagnosis* / Q000453:epidemiology; D012044:Regression Analysis; D012189:Retrospective Studies; D016896:Treatment Outcome