title: Laparoscopic ovarian transposition before pelvic irradiation: a Saudi tertiary center experience.
abstract: OBJECTIVE
  To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia.
  
  
  METHODS
  Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy.
  
  
  METHODS
  Laparoscopic ovarian transposition to paracolic gutters with uterine conservation.
  
  
  METHODS
  Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level.
  
  
  RESULTS
  Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up.
  
  
  CONCLUSIONS
  Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.
authors.affiliation: King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. i_albadawi@yahoo.com
authors.forename: Ismail A
authors.initials: IA
authors.lastname: Al-Badawi
authors.forename: Murad
authors.initials: M
authors.lastname: Al-Aker
authors.forename: Jamal
authors.initials: J
authors.lastname: AlSubhi
authors.forename: Hany
authors.initials: H
authors.lastname: Salem
authors.forename: Alaa
authors.initials: A
authors.lastname: Abduljabbar
authors.forename: Khalid
authors.initials: K
authors.lastname: Balaraj
authors.forename: Adnan
authors.initials: A
authors.lastname: Munkarah
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006779:Hospitals, Public; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008875:Middle Aged; D010053:Ovary / Q000528:radiation effects / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D017697:Premenopause; D011835:Radiation Protection / Q000379:methods; D018714:Radiotherapy, Adjuvant; D020127:Recovery of Function; D018570:Risk Assessment; D012529:Saudi Arabia; D016896:Treatment Outcome