[Epidemiology of fungaemia in a paediatric hospital of high complexity].
BACKGROUND
A retrospective study on the epidemiology of fungaemia due to yeasts of medical importance at the Hospital Nacional de Pediatría Prof. Dr. J. Garrahan, Buenos Aires was conducted between September 2001 and September 2003.


OBJECTIVE
To learn the distribution of yeast species and to evaluate their in vitro antifungal susceptibility profile.


METHODS
The minimum inhibitory concentration (MIC) was determined according to the CLSI M27-A2 procedure, and time kill curves against amphotericin B were also performed.


CONCLUSIONS
The species isolated were Candida parapsilosis (32.6% of isolates); Candida albicans (26.5%), Candida tropicalis (24.5%), and other yeasts (16.4%). Candida isolates were susceptible to the antifungals evaluated, but amphotericin B-tolerant isolates were detected using time kill curves.
Santos
Patricia Ester
PE
Servicio de Microbiología, Hospital Nacional de Pediatría, Dr. J.P. Garrahan, Buenos Aires, Argentina. bernabesa@yahoo.com.ar
Córdoba
Susana
S
Carrillo-Muñoz
Alfonso
A
Rodero
Laura
L
Rubeglio
Etelvina
E
Soria
Marcelo
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D016469:Fungemia / Q000453:epidemiology* / Q000382:microbiology; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies