title: Acute effects of passive smoking on endothelial function.
abstract: Impairment of endothelial functions has been shown to occur after acute and chronic exposure to passive smoking (PS), as assessed by flow-mediated dilatation (FMD) of the brachial artery. A total of 61 participants, 30 male and 31 female, mean ages 26 (18-36) were enrolled in the study. All were clinically well and nonsmokers. All participants stayed for 30 minutes in the smoking room. Carbon monoxide (CO) level was 7.42 ± 0.98 ppm (4.71-10.50). Mean carboxyhemoglobin (COHb) levels of participants were significantly elevated after PS. Mean FMD was 18.6% ± 9% and decreased to 12.4% ± 7% after PS (P < .001). In the current study, with more number of participants at lower CO concentrations (7.42 ppm) and with smaller increase in COHb (51%) significant reduction (33%, P < .001) in FMD was observed.
authors.affiliation: Cardiology Department, School of Medicine, Cumhuriyet University, Sivas, Turkey. dribrahimgul@hotmail.com
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Gül
authors.forename: Hekim
authors.initials: H
authors.lastname: Karapinar
authors.forename: Mikail
authors.initials: M
authors.lastname: Yarlioglues
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ozdogru
authors.forename: Mehmet Gungor
authors.initials: MG
authors.lastname: Kaya
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yilmaz
authors.forename: Okan Onur
authors.initials: OO
authors.lastname: Turgut
authors.forename: Izzet
authors.initials: I
authors.lastname: Tandogan
authors.forename: Namik Kemal
authors.initials: NK
authors.lastname: Eryol
mesh_terms: D000293:Adolescent; D000328:Adult; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*; D014463:Ultrasonography
chemical_list: D014028:Tobacco Smoke Pollution