Deferasirox induced liver injury in haemochromatosis.
Durg-induced liver injury is a common side-effect of many medicines. It is particularly problem when the original condition under treatment is already causing liver damage. This report describes the hepatotoxicity induced by Deferasirox in a patient with haemochromatosis with a discussion of possible pathogenetic mechanism.
Aslam
Naeem
N
Department of Gastroenterology and Hepatology, University of Louisville, KY 40202, USA. drnaeem12@gmail.com
Mettu
Parveen
P
Marsano-Obando
Luis S
LS
Martin
Anthony
A
D001565:Benzoates / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D000077588:Deferasirox; D005260:Female; D006432:Hemochromatosis / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007502:Iron Chelating Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use
D001565:Benzoates; D007502:Iron Chelating Agents; D014230:Triazoles; D000077588:Deferasirox