title: Negative pressure external drainage of the pancreatic duct in pancreaticoduodenectomy.
abstract: OBJECTIVE
  Despite the development of surgical techniques, postoperative pancreatic fistula is still one of the main causes of serious morbidity after pancreaticoduodenectomy. Nevertheless numerous studies have been done, studies on preventing pancreatic fistula are lacking. This study is focused on the effectiveness of negative pressure external drainage for pancreaticojejunostomy in pancreaticoduodenectomy patients.
  
  
  METHODS
  Seventy-six patients were scheduled for pancreaticoduodenectomy at Soonchunhyang University Hospital from January of 2003 to August of 2007. Negative suction drainage group (n = 41) and no negative suction drainage group (n = 35) were compared by patient characteristics, parameters related to operation, and complications.
  
  
  RESULTS
  There were no statistical differences between both groups in patient demographics and parameters related to operation. The complication rates were significantly lower in negative suction drainage group in terms of postoperative bleeding (P = 0.012), choledochojejunostomy leak (P = 0.014), and pancreatic fistula (P = 0.018).
  
  
  CONCLUSIONS
  This retrospective study showed that external stenting with negative pressure suction drainage of the pancreatic duct has significantly reduced the rate of pancreatic fistula in duct-to-mucosa pancreaticojejunostomy with improved surgical outcomes.
authors.affiliation: Department of Surgery, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: Zisun
authors.initials: Z
authors.lastname: Kim
authors.forename: Jeongman
authors.initials: J
authors.lastname: Kim
authors.forename: Joo Kim
authors.initials: JK
authors.lastname: Min
authors.forename: Kyung Yul
authors.initials: KY
authors.lastname: Hur
authors.forename: Dongho
authors.initials: D
authors.lastname: Choi
authors.forename: Daekwan
authors.initials: D
authors.lastname: Seo
authors.forename: Jung Hoon
authors.initials: JH
authors.lastname: Kim
authors.forename: Kyung-Jae
authors.initials: KJ
authors.lastname: Lee
authors.forename: Akimasa
authors.initials: A
authors.lastname: Nakao
mesh_terms: D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts; D010185:Pancreatic Fistula / Q000517:prevention & control*; D016577:Pancreaticoduodenectomy / Q000379:methods*; D019990:Perioperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D015607:Stents