title: Neonatal gastrin-releasing peptide receptor blockade reduces maternal odor preference in rats.
abstract: Alterations in attachment behavior might play a role in the dysfunction in social behavior displayed by autistic infants. Here we show that neonatal gastrin-releasing peptide receptor (GRPR) blockade induces a reduction in maternal odor preference, a task involving attachment behavior, in infant rats. These findings provide the first evidence that the GRPR regulates odor preference, supporting the view that the GRPR is involved in attachment and social behaviors.
authors.affiliation: Neurobiology and Developmental Biology Laboratory, Faculty of Biosciences, Pontifical Catholic University, Porto Alegre, RS, Brazil.
authors.forename: Vanessa A
authors.initials: VA
authors.lastname: Garcia
authors.forename: Arethuza S
authors.initials: AS
authors.lastname: Dornelles
authors.forename: Juliana
authors.initials: J
authors.lastname: Presti-Torres
authors.forename: Luisa A
authors.initials: LA
authors.lastname: Alcalde
authors.forename: Luis Henrique
authors.initials: LH
authors.lastname: Halmenschlager
authors.forename: Gilberto
authors.initials: G
authors.lastname: Schwartsmann
authors.forename: Rafael
authors.initials: R
authors.lastname: Roesler
authors.forename: Aldo B
authors.initials: AB
authors.lastname: Lucion
authors.forename: Nadja
authors.initials: N
authors.lastname: Schröder
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001362:Avoidance Learning / Q000187:drug effects; D001839:Bombesin / Q000031:analogs & derivatives* / Q000494:pharmacology; D002755:Choice Behavior / Q000187:drug effects*; D008297:Male; D009812:Odorants; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats; D018004:Receptors, Bombesin / Q000037:antagonists & inhibitors*
chemical_list: D010446:Peptide Fragments; D018004:Receptors, Bombesin; C071363:bombesin (6-14), Tpi(6)-Leu(13)-psi(CH2NH)-Leu(14)-; D001839:Bombesin