Molecular imaging of membrane proteins and microfilaments using atomic force microscopy.
Atomic force microscopy (AFM) is an emerging technique for a variety of uses involving the analysis of cells. AFM is widely applied to obtain information about both cellular structural and subcellular events. In particular, a variety of investigations into membrane proteins and microfilaments were performed with AFM. Here, we introduce applications of AFM to molecular imaging of membrane proteins, and various approaches for observation and identification of intracellular microfilaments at the molecular level. These approaches can contribute to many applications of AFM in cell imaging.
Jung
Se-Hui
SH
Department of Molecular and Cellular Biochemistry, Kangwon National University School of Medicine, Chuncheon 200-701, Korea.
Park
Donghyun
D
Park
Jae Hyo
JH
Kim
Young-Myeong
YM
Ha
Kwon-Soo
KS
D008841:Actin Cytoskeleton / Q000502:physiology*; D002462:Cell Membrane / Q000648:ultrastructure; D008565:Membrane Proteins / Q000502:physiology*; D018625:Microscopy, Atomic Force; D057054:Molecular Imaging / Q000379:methods*
D008565:Membrane Proteins