[Rifampin-induced severe aseptic meningitis].
We report the first case of acute drug-induced aseptic meningitis (DIAM) due to rifampin in a young female with systemic lupus erythematosus (SLE). DIAM is uncommon and its diagnosis is often difficult. This type of drug hypersensitivity is more frequently observed in patients with a history of auto-immune disease, particularly SLE. The major categories of causative agents are: nonsteroidal anti-inflammatory drugs, antimicrobials, intravenous immunoglobulins and biotherapies.
Tuleja
E
E
Service de médecine interne, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France. eva.tuleja@egp.aphp.fr
Bourgarit
A
A
Abuaf
N
N
Le Beller
C
C
Séréni
D
D
D000328:Adult; D000904:Antibiotics, Antitubercular / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008582:Meningitis, Aseptic / Q000139:chemically induced*; D012293:Rifampin / Q000009:adverse effects*; D012720:Severity of Illness Index
D000904:Antibiotics, Antitubercular; D012293:Rifampin