title: Reversible splenium lesion of the corpus callosum in hemorrhagic fever with renal failure syndrome.
abstract: This is the first case of virus-associated encephalitis/encephalopathy in which the pathogen was Hantaan virus. A 53-yr-old man presented fever, renal failure and a hemorrhagic tendency and he was diagnosed with hemorrhagic fever with renal failure syndrome (HFRS). In the course of his illness, mild neurologic symptoms such as dizziness and confusion developed and magnetic resonance images revealed a reversible lesion in the splenium of the corpus callosum. This case suggests that HFRS patients with neurologic symptoms like dizziness and mental slowing should be considered to have structural brain lesions and to require brain imaging studies.
authors.affiliation: Department of Neurology, Chungbuk National University School of Medicine, Cheongju, Korea.
authors.forename: Shin-Hye
authors.initials: SH
authors.lastname: Baek
authors.forename: Dong-Ick
authors.initials: DI
authors.lastname: Shin
authors.forename: Hyung-Suk
authors.initials: HS
authors.lastname: Lee
authors.forename: Sung-Hyun
authors.initials: SH
authors.lastname: Lee
authors.forename: Hye-Young
authors.initials: HY
authors.lastname: Kim
authors.forename: Kyeong Seob
authors.initials: KS
authors.lastname: Shin
authors.forename: Seung Young
authors.initials: SY
authors.lastname: Lee
authors.forename: Ho-Seong
authors.initials: HS
authors.lastname: Han
authors.forename: Hyun Jeong
authors.initials: HJ
authors.lastname: Han
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Lee
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D003337:Corpus Callosum / Q000473:pathology*; D003937:Diagnosis, Differential; D018063:Hantaan virus / Q000276:immunology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D006435:Renal Dialysis
chemical_list: D000914:Antibodies, Viral