title: Anticonvulsant hypersensitivity syndrome treated with intravenous immunoglobulin.
abstract: Anticonvulsant hypersensitivity syndrome is a severe, potentially life-threatening, reaction to the aromatic anticonvulsant medications. Reported here is a case of anticonvulsant hypersensitivity syndrome secondary to phenobarbital in a 2-year-old boy; he responded to drug withdrawal, corticosteroids, and intravenous immunoglobulin. The literature regarding treatment of this syndrome is reviewed.
authors.affiliation: Department of Neurology, Massachusetts General Hospital, Boston, MA, USA. david.dredge@bhs.org
authors.forename: David C
authors.initials: DC
authors.lastname: Dredge
authors.forename: Elizabeth C
authors.initials: EC
authors.lastname: Parsons
authors.forename: Lindsay P
authors.initials: LP
authors.lastname: Carter
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Staley
mesh_terms: D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D010634:Phenobarbital / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D010634:Phenobarbital