Multicolored redox active upconverter cerium oxide nanoparticle for bio-imaging and therapeutics.
Cytocompatible, co-doped cerium oxide nanoparticles exhibited strong upconversion properties that were found to kill lung cancer cells by inducing apoptosis thereby demonstrating the potential to be used as clinical contrast agents for imaging and as therapeutic agents for treatment of cancer.
Babu
Suresh
S
Advanced Materials Processing and Analysis Centre, Department of Mechanical, Materials and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.
Cho
Jung-Hyun
JH
Dowding
Janet M
JM
Heckert
Eric
E
Komanski
Chris
C
Das
Soumen
S
Colon
Jimmie
J
Baker
Cheryl H
CH
Bass
Michael
M
Self
William T
WT
Seal
Sudipta
S
D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002563:Cerium / Q000737:chemistry / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D042783:Endothelial Cells / Q000187:drug effects*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010316:Particle Size; D013499:Surface Properties
D000970:Antineoplastic Agents; D002563:Cerium; C030583:ceric oxide