title: [Research progress of full-thickness tissue engineered skin].
abstract: OBJECTIVE
  To review the latest research progress of full-thickness tissue engineered skin (FTTES), to thoroughly understand its current state of research and application so as to lay a solid foundation for developing new type FTTES and improving the quality of skin substitutes.
  
  
  METHODS
  Domestica and international literature concerning FTTES in recent years was extensively reviewed and comprehensively analyzed.
  
  
  RESULTS
  Some progress of FTTES had made in seed cells, scaffold materials and construction, and some therapeutic efficacy had also been achieved in clinical application. But FTTES grafting successful rate was lower, and it had no complete skin structure and had not reached the requirements of clinical application.
  
  
  CONCLUSIONS
  FTTES is an ideal skin substitute and has great development prospects. However, in seed cells, scaffold materials, construction and applications of FTTES, further studied is still needed.
authors.affiliation: Department of Burn and Plastic Surgery, First Hospital Affiliated to General Hospital of PLA, Beijing, 100048, P R China.
authors.forename: Yanfu
authors.initials: Y
authors.lastname: Han
authors.forename: Tianjun
authors.initials: T
authors.lastname: Sun
authors.forename: Dongjie
authors.initials: D
authors.lastname: Li
authors.forename: Ran
authors.initials: R
authors.lastname: Tao
authors.forename: Jiake
authors.initials: J
authors.lastname: Chai
mesh_terms: D016038:Skin Transplantation; D017768:Skin, Artificial; D023822:Tissue Engineering