title: An improved sensitivity nonenzymatic glucose biosensor based on a CuxO modified electrode.
abstract: An enzymeless biosensor based on CuxO/Cu electrode was investigated in this study. The XRD analysis confirmed that CuxO nanostructured material was composed of Cu2O and CuO. The FESEM images showed that the catalysts were flower-like with large surface area. From cyclic voltammograms, the peak current of CuxO/Cu electrode was 6, 6.3 and 1.7 times higher than that of the Cu foil, Cu2O/GCE and CuO/GCE electrodes, respectively. The biosensor based on CuxO/Cu exhibited excellent performance for glucose detection, giving a linear dependence between current and glucose concentration (R=0.996), with a low detection limit (0.049 mM) and high sensitivity (1.62 mA cm(-2) mM(-1)). Finally, the CuxO/Cu sensor was applied and checked in the glucose determination in blood serum samples.
authors.affiliation: Changchun Institute of Applied Chemistry, Graduate School of Chinese Academy of Science, 5625 Renmin Street, Changchun 130022, PR China.
authors.forename: Cuiling
authors.initials: C
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Su
authors.forename: Senwang
authors.initials: S
authors.lastname: Zhang
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Lv
authors.forename: Hailong
authors.initials: H
authors.lastname: Xia
authors.forename: Yujiang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D001786:Blood Glucose / Q000032:analysis*; D003217:Conductometry / Q000295:instrumentation*; D003300:Copper / Q000737:chemistry*; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose; D003300:Copper; C030973:cupric oxide