title: The intelligent, painless, "germ-free" colonoscopy: A Columbus' egg for increasing population adherence to colorectal cancer screening?
abstract: Colorectal cancer (CRC) represents a major cause of morbidity and mortality. Although it is widely accepted that CRC screening in average risk populations lowers CRC incidence and mortality, a disappointedly low adherence rate to both faecal occult blood testing and colonoscopy-based screening programs has been observed in Italy and in other European countries. Main reasons for the low acceptance of colonoscopy-based CRC screening has been ascribed to lack of recommendations given by general practitioners, fear of discomfort or complications, embarrassment, and avoidance of unpleasant preparation. New advances in endoscopic technology such as colon capsule and robotic colonoscopy might represent the ideal tool for CRC screening since they reduce or eliminate procedure-related pain and discomfort. Moreover, no disinfection between procedures is required. Motion of the new probes along the gastrointestinal tract is achieved either in passive modality by utilizing the gut peristalsis (colon capsule) or in active "intelligent" modality by means of computer-assisted propulsion (robotic colonoscopy). In this review, the preliminary clinical results obtained with the new devices are summarized. It is expected that the new instruments will be soon available in clinical practice with the hope of increasing adherence to CRC screening programs.
authors.affiliation: Division of Gastroenterology and Digestive Endoscopy, IRCCS Casa Sollievo della Sofferenza Hospital, 71013 San Giovanni Rotondo, Italy. f.perri@operapadrepio.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Perri
authors.forename: Angelo
authors.initials: A
authors.lastname: Iacobellis
authors.forename: Marco
authors.initials: M
authors.lastname: Gentile
authors.forename: Emanuele
authors.initials: E
authors.lastname: Tumino
authors.forename: Angelo
authors.initials: A
authors.lastname: Andriulli
mesh_terms: D053704:Capsule Endoscopy; D003113:Colonoscopy / Q000295:instrumentation; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D055088:Early Detection of Cancer; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D007558:Italy; D008297:Male; D009780:Occult Blood; D010349:Patient Compliance; D012371:Robotics