title: Nonclinical obsessive-compulsive symptoms and executive functions in schizophrenia.
abstract: The impact of nonclinical obsessive-compulsive symptoms (OCS) on neuropsychological functioning in schizophrenia has received little investigation. The authors evaluated whether severity and subtype of OCS are associated with executive functioning in schizophrenia. Twenty-nine patients with schizophrenia and 32 healthy comparison subjects completed questionnaire and performance-based measures of executive functioning. Overall OCS severity in patients was associated with poorer monitoring and cognitive flexibility. Obsessing, hoarding, and checking were related to poorer executive functioning in daily life. Performance-based scores showed few correlations with OCS. Findings indicate that severity of nonclinical OCS subtypes contributes to the heterogeneity of executive functions in schizophrenia.
authors.affiliation: Dartmouth Medical School, Department of Psychiatry, One Medical Center Dr., Lebanon, NH 03756-0001, USA.
authors.forename: Sheba R
authors.initials: SR
authors.lastname: Kumbhani
authors.forename: Robert M
authors.initials: RM
authors.lastname: Roth
authors.forename: Carrie L
authors.initials: CL
authors.lastname: Kruck
authors.forename: Laura A
authors.initials: LA
authors.lastname: Flashman
authors.forename: Thomas W
authors.initials: TW
authors.lastname: McAllister
mesh_terms: D000328:Adult; D003192:Compulsive Behavior / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009770:Obsessive Behavior / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires