Noncoding RNAs: the missing "linc" in p53-mediated repression.
The tumor suppressor protein p53 coordinates the cellular response to stress through regulation of gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a new player in p53-mediated repression of genes involved in apoptosis.
Barsotti
Anthony M
AM
Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
Prives
Carol
C