Zinc and biotin deficiencies after pancreaticoduodenectomy.
We report zinc and biotin deficiencies after pancreaticoduodenectomy in a 16 year old female presenting clinically with marked alopecia, total body hair loss, dry skin with scales, and maculopathy with significant vision loss. These micronutrient deficiencies likely occurred due to resection of the duodenum and proximal jejunum, sites of primary absorption of several micronutrients and their protein carriers, including zinc and biotin. Early diagnosis is essential to prevent irreversible sequelae. Adequate supplementation of zinc and biotin as well as dietary advice is needed for clinical improvement.
Yazbeck
N
N
Department of Pediatric Medicine and Adolescent, American University of Beirut-Medical Center (AUB-MC), Beirut, Lebanon. ny12@aub.edu.lb
Muwakkit
S
S
Abboud
M
M
Saab
R
R
D000169:Acrodermatitis / Q000209:etiology*; D000293:Adolescent; D001710:Biotin / Q000172:deficiency*; D005234:Fatty Liver / Q000209:etiology; D005260:Female; D006801:Humans; D008286:Malabsorption Syndromes / Q000209:etiology; D010190:Pancreatic Neoplasms / Q000601:surgery; D016577:Pancreaticoduodenectomy / Q000009:adverse effects*; D015032:Zinc / Q000172:deficiency
D001710:Biotin; D015032:Zinc