title: Simple and efficient preparation of 2,5-disubstituted oxazoles via a metal-free-catalyzed cascade cyclization.
abstract: A practical and simple synthesis of 2,5-disubstituted oxazoles was developed via an iodine-catalyzed tandem oxidative cyclization. A wide range of common commercial aromatic aldehydes can be used as reaction substrates, which displayed excellent functional group compatibility in this reaction.
authors.affiliation: Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, P. R. China.
authors.forename: Changfeng
authors.initials: C
authors.lastname: Wan
authors.forename: Linfeng
authors.initials: L
authors.lastname: Gao
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.forename: Jintang
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000447:Aldehydes; D010080:Oxazoles; D007455:Iodine