Iron-catalyzed Suzuki-Miyaura coupling of alkyl halides.
In the presence of novel iron(II) chloride-diphosphine complexes and magnesium bromide, lithium arylborates react with primary and secondary alkyl halides to give the corresponding coupling products in good to excellent yields. High functional group compatibility is also demonstrated in the reactions of substrates possessing reactive substituents, such as alkoxycarbonyl, cyano, and carbonyl groups.
Hatakeyama
Takuji
T
International Research Center for Elements Science, Institute for Chemical Research, Kyoto University, Uji, Kyoto, 611-0011, Japan.
Hashimoto
Toru
T
Kondo
Yoshiyuki
Y
Fujiwara
Yuichi
Y
Seike
Hirofumi
H
Takaya
Hikaru
H
Tamada
Yoshinori
Y
Ono
Teruo
T
Nakamura
Masaharu
M
D002384:Catalysis; D018360:Crystallography, X-Ray; D005296:Ferrous Compounds / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010720:Phosphines / Q000138:chemical synthesis* / Q000737:chemistry
D005296:Ferrous Compounds; D006846:Hydrocarbons, Halogenated; D010720:Phosphines; C029451:ferrous chloride