Room temperature palladium-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids.
A novel Pd-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids is realized at room temperature. This reaction provides efficient access to o-acyl acetanilides under mild conditions.
Fang
Ping
P
Department of Chemistry and Chemical Biology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana 46202, USA.
Li
Mingzong
M
Ge
Haibo
H
D000083:Acetanilides / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D003653:Decarboxylation; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature
D000083:Acetanilides; D002264:Carboxylic Acids; D007659:Ketones; D009942:Organometallic Compounds; D010165:Palladium