title: Stable angina pectoris: what does the current clinical evidence tell us?
abstract: Coronary artery disease is the leading cause of death in the United States. The combination of noninvasive cardiovascular testing and invasive cardiac procedures accounts for a substantial portion of the yearly healthcare expenditure in the United States. Although the diagnosis of ischemically-driven chest pain may appear to be simple and straightforward, it often takes an astute clinician to confirm that clinically significant coronary artery blockage is the cause of a patient's chest pain. Cardiovascular research has provided convincing evidence that aggressive treatment of hypertension and hyperlipidemia--along with a management plan, based on the patient's combined risk factor profile, that includes blood glucose assessment, tobacco cessation, weight loss, healthy eating choices, and consistent aerobic exercise--must be provided to achieve optimal care for our patients. Over the ensuing decade, we will likely continue to see a shift away from routine percutaneous treatment of coronary lesions in favor of an aggressive assessment of a patient's cardiac risk profile followed by a treatment plan centered on active patient involvement including appropriate lifestyle changes and selective medications.
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Disease, University of Michigan Medical Center, Ann Arbor, MI, USA. kentobin@umich.edu
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Tobin
mesh_terms: D000787:Angina Pectoris / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000628:therapy; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D002637:Chest Pain / Q000175:diagnosis / Q000473:pathology; D008078:Cholesterol, LDL / Q000187:drug effects; D003937:Diagnosis, Differential; D018450:Disease Progression; D005080:Exercise Test; D005081:Exercise Therapy; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000473:pathology; D006973:Hypertension / Q000188:drug therapy / Q000473:pathology; D008019:Life Style; D024821:Metabolic Syndrome; D012307:Risk Factors; D016540:Smoking Cessation
chemical_list: D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL