Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein labeling.
We present an efficient method to synthesize three new asymmetric trimethine cyanine dyes containing only one carboxylic acid group for bioconjugation. Two of them have better protein labeling performance than other conventional cyanine dyes due to their particular structure design.
Song
Fengling
F
State Key Laboratory of Fine Chemicals, Dalian University of Technology, 158 Zhongshan Road, Dalian 116012, PR China.
Wang
Li
L
Qiao
Xiaoqiang
X
Wang
Bingshuai
B
Sun
Shiguo
S
Fan
Jiangli
J
Zhang
Lihua
L
Peng
Xiaojun
X
D000818:Animals; D002232:Carbocyanines / Q000138:chemical synthesis* / Q000737:chemistry; D002417:Cattle; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013050:Spectrometry, Fluorescence
D002232:Carbocyanines; D005456:Fluorescent Dyes; C089187:cyanine dye 3; D012710:Serum Albumin, Bovine