title: Race, socioeconomic status, and response to methotrexate treatment of ectopic pregnancy in an urban population.
abstract: On the basis of the documented racial disparities in ectopic pregnancy incidence and mortality we hypothesized that African-American women with ectopic pregnancy would be more likely than white women to have treatment failure with methotrexate. In this retrospective cohort study, a racial disparity in methotrexate effectiveness was not found, but a significant relationship between low socioeconomic status and methotrexate failure was demonstrated.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. sbutts@obgyn.upenn.edu
authors.forename: Samantha F
authors.initials: SF
authors.lastname: Butts
authors.forename: Erika
authors.initials: E
authors.lastname: Gibson
authors.forename: Mary D
authors.initials: MD
authors.lastname: Sammel
authors.forename: Alka
authors.initials: A
authors.lastname: Shaunik
authors.forename: Brianna
authors.initials: B
authors.lastname: Rudick
authors.forename: Kurt
authors.initials: K
authors.lastname: Barnhart
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D004305:Dose-Response Relationship, Drug; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D015994:Incidence; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy* / Q000453:epidemiology / Q000208:ethnology*; D044469:Racial Groups / Q000706:statistics & numerical data; D012923:Social Class; D017211:Treatment Failure; D016896:Treatment Outcome; D014505:Urban Population / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate