[In vitro efficacy of Ingavirin against the pandemic influenza virus A(H1N1/09)v].
Ingavirin was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell culture. The hemagglutinin and cytopathic activity of the influenza virus strains decreased at entering Ingavirin in vitro.
Shishkina
L N
LN
Nebol'sin
V E
VE
Kabanov
A S
AS
Skarnovich
M O
MO
Erdyneeva
U B
UB
Mazurkova
N A
NA
Serova
O A
OA
Stavskiĭ
E A
EA
Drozdov
I G
IG
D000577:Amides / Q000494:pharmacology*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002208:Caproates; D002460:Cell Line; D003998:Dicarboxylic Acids / Q000494:pharmacology*; D004285:Dogs; D007093:Imidazoles / Q000494:pharmacology*; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects*; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects; D053124:Influenza A Virus, H5N1 Subtype / Q000187:drug effects; D013997:Time Factors
D000577:Amides; D000998:Antiviral Agents; D002208:Caproates; D003998:Dicarboxylic Acids; D007093:Imidazoles; C539419:pentanedioic acid imidazolyl ethanamide