Comparative analysis of endometrial blood flow on the day of hCG by 2D Doppler in two groups of women with or without genital tuberculosis undergoing IVF-ET in a developing country.
OBJECTIVE
To evaluate the endometrial blood flow by two-dimensional power Doppler ultrasound as possible implantation markers and pregnancy predictors in women with and without genital tuberculosis undergoing in vitro fertilization-embryo transfer cycle (IVF-ET).


METHODS
This was a prospective observational study. A total of 183 infertile women were recruited from our IVF-ET program from January to December 2009. Women with tubal factor, male factor and unexplained infertility were included in the study.


RESULTS
The age, duration of infertility and BMI of the women were comparable in both the groups. The mean gonadotropin usage in Group 1 was 2,881.3 IU (±SD 949.7) and 3,077.8 (±SD 927.9) in Group 2. Total number of eggs obtained, duration (days) of stimulation, Estradiol (E2) concentration and endometrial thickness (in mm) showed no significant difference in the two groups. Even the peak systolic velocity, pulsatility index (PI) and resistance index (RI) was not statistically significant between the two groups. Pregnancy and implantation was higher in women with endometrial flow in zone 3 in both the groups though it did not reach any statistical significance.


CONCLUSIONS
The present study showed no difference in endometrial blood flow and pregnancy rates in patients with or without genital tuberculosis.
Singh
Neeta
N
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Bahadur
Anupama
A
Mittal
Suneeta
S
Malhotra
Neena
N
Bhatt
Ashok
A
D000328:Adult; D006063:Chorionic Gonadotropin / Q000008:administration & dosage*; D003906:Developing Countries; D004624:Embryo Transfer; D004717:Endometrium / Q000098:blood supply* / Q000000981:diagnostic imaging*; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology; D008875:Middle Aged; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D012039:Regional Blood Flow; D014384:Tuberculosis, Female Genital / Q000503:physiopathology*; D018615:Ultrasonography, Doppler, Color / Q000379:methods*; D055815:Young Adult
D006063:Chorionic Gonadotropin; D004958:Estradiol