Supramolecular assemblies in ionic liquid catalysis for aza-Michael reaction.
Supramolecular assemblies formed by a relay of cooperative hydrogen bonds and charge-charge interactions have been identified/characterized by (+ve) ESI and MALDI-TOF-TOF MS and MS-MS studies during the aza-Michael reaction of amines with alpha,beta-unsaturated carbonyl compounds in the presence of ionic liquids (ILs) digging out the role of catalysis by ILs, forming the basis of rational design/selection as organocatalysts, and offering a diagnostic model to predict/rationalize the selectivity of the aza-Michael reaction in a competitive environment.
Roy
Sudipta Raha
SR
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India.
Chakraborti
Asit K
AK
D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D000588:Amines; D007659:Ketones