title: Ag/Al(OH)3 mesoporous nanocomposite film as antibacterial agent.
abstract: In this study, Ag/Al(OH)(3) mesoporous nanocomposite film was fabricated for antibacterial agent. As a matrix, a mesoporous Al(OH)(3) layer was prepared by alkali surface modification of an Al substrate. Subsequently, mesoporous Al(OH)(3) matrix was immersed in a polyol solution for 4h at an elevated temperature to deposit silver nanoparticles (Ag NPs) by in situ dispersion. The Al(OH)(3) porous matrix had flaky crystals weaved and covered all substrate surface so that the specific surface area was considerably increased because of voids having several tens of nanometers between the flakes. After in situ dispersion of Ag NPs by polyol process, the Ag NPs were nucleated and grown at the surface of mesoporous Al(OH)(3) layer with tight binding. In antibacterial activity, Ag/Al(OH)(3) mesoporous nanocomposite film demonstrated an excellent bacterial growth inhibition property. It is believed that the Ag/Al(OH)(3) mesoporous nanocomposite film is suitable for the antibacterial agent in a wide variety of biomedical applications.
authors.affiliation: Division of Materials Science and Engineering, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Republic of Korea.
authors.forename: Young Ik
authors.initials: YI
authors.lastname: Seo
authors.forename: Ki Ho
authors.initials: KH
authors.lastname: Hong
authors.forename: Dae-Gun
authors.initials: DG
authors.lastname: Kim
authors.forename: Young Do
authors.initials: YD
authors.lastname: Kim
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000633:toxicity; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D007700:Kinetics; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry* / Q000633:toxicity / Q000648:ultrastructure; D056951:Photoelectron Spectroscopy; D016062:Porosity; D012834:Silver / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D000537:Aluminum Oxide