title: Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation.
abstract: Personalized medicine is increasingly important in cancer treatment for its role in staging and its potential to improve stratification of patients. Different types of molecules, genes, proteins, and metabolites are being extensively explored as potential biomarkers. This review discusses the major findings and potential of tissue metabolites determined by high-resolution magic angle spinning magnetic resonance spectroscopy for cancer detection, characterization, and treatment monitoring.
authors.affiliation: Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. tone.f.bathen@ntnu.no
authors.forename: Tone F
authors.initials: TF
authors.lastname: Bathen
authors.forename: Beathe
authors.initials: B
authors.lastname: Sitter
authors.forename: Torill E
authors.initials: TE
authors.lastname: Sjøbakk
authors.forename: May-Britt
authors.initials: MB
authors.lastname: Tessem
authors.forename: Ingrid S
authors.initials: IS
authors.lastname: Gribbestad
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D055432:Metabolomics / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy*