Factors discriminating spontaneous pursed-lips breathing use in patients with COPD.
Pursed-lips breathing (PLB) is often spontaneously performed by chronic obstructive pulmonary disease (COPD) patients. The aim of this study was to evaluate spontaneous PLB prevalence and to identify factors discriminating its use. Fifty-seven patients with COPD (FEV(1) = 44.3 +/- 17.4%pred) underwent pulmonary function testing and two incremental bicycle exercise tests. Peak workload (Wpeak), oxygen uptake (VO(2)peak), breathing pattern, and dyspnea (Borg scale) were measured in the first exercise test and spontaneous PLB performance in the second. Six patients spontaneously performed pursed-lips breathing during rest (PLBrest), exercise and recovery, 18 during exercise and recovery (PLBex), 7 during recovery only (PLBrec), 20 not at all (PLBno), and 6 performed other expiratory resistive maneuvers. PLBrest and PLBex patients exhibited a lower Wpeak, O(2) uptake, and minute ventilation (V(E)), greater expiratory flow limitation and higher slopes relating dyspnea to V(E) or W (%predicted). PLBrest patients were more hypercapnic, had a lower exercise tolerance and diffusion capacity, and greater flow limitation and hyperinflation. PLBrec and PLBno patients were indistinguishable with regard to pulmonary function, dyspnea, and exercise performance. The most significant independent predictors of spontaneous PLB use during exercise were FEV(1)/FVC and the slope relating dyspnea to V(E). Spontaneous PLB is most often performed by COPD subjects when ventilation is stimulated by exercise, and during recovery from exercise. Severity of airflow obstruction and the dyspnea experienced during exercise play an important role in determining whether or not PLB is spontaneously performed by COPD patients.
Spahija
Jadranka
J
McGill University, Montréal, Québec, Canada. jadranka.spahija@mcgill.ca
Marchie
Michel de
Md
Ghezzo
Heberto
H
Grassino
Alejandro
A
D000368:Aged; D004417:Dyspnea / Q000503:physiopathology; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009058:Mouth Breathing; D010101:Oxygen Consumption; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D012129:Respiratory Function Tests