Use of scanning electron microscopy in the study of nephrotoxin-induced renal proximal tubular damage in vitro.
Scanning electron microscopy was used to study cephaloridine and gentamicin-induced renal cell injury in vitro. Exposure of renal proximal tubular cells to these toxicants produced changes in cell surface morphology that occurred at concentrations similar to (or below) those affecting neutral red uptake or monolayer permeability.
Rees
J A
JA
Sterling Winthrop Pharmaceuticals Research Division, Willowburn Avenue, Alnwick, Northumberland NE66 2JH, UK.
Evans
J G
JG
Blackmore
M
M
Spencer
A J
AJ
Gray
T J
TJ