title: Total synthesis of grassypeptolide.
abstract: The first total synthesis of grassypeptolide, an anticancer cyclodepsipeptide isolated from marine cyanobacteria, has been achieved in 17 steps and an overall 11.3% yield.
authors.affiliation: Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, University Town of Shenzhen, Xili, Nanshan District, Shenzhen, China 518055.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiangyou
authors.initials: X
authors.lastname: Xing
authors.forename: Zhengshuang
authors.initials: Z
authors.lastname: Xu
authors.forename: Tao
authors.initials: T
authors.lastname: Ye
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D000458:Cyanobacteria / Q000737:chemistry*; D047630:Depsipeptides / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D047630:Depsipeptides; C528460:grassypeptolide