title: [Helicobacter pylori infection and symptoms of gastroesophageal reflux disease].
abstract: The effect of Helicobacter pylori (H. pylori) on gastroesophageal reflux disease (GERD) is controversial. The aim of this study was to assess the relationship between H. pylori infection and symptoms of GERD.
  
  
  METHODS
  112 patients (41 men, 71 women; mean 51 +/- 9.54 yeas, range 21-71 yeas) with symptomatic GERD were studied. The serologic evidence of H. pylori infection (IgG antibodies) was determined by means of ELISA ( enzyme-liked immunosorbent assay) in all patients.
  
  
  RESULTS
  There were 59 (53.2%) patients infected with H. pylori. Statistical analysis did not reveal any significant different symptom scores between patients with and those without H. pylori infection.
  
  
  CONCLUSIONS
  H. pylori infection plays no role on the development of GERD symptoms.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Institutul de Gastroenterologie şi Hepatologie Iaşi.
authors.forename: I
authors.initials: I
authors.lastname: Klitorakis
authors.forename: C
authors.initials: C
authors.lastname: Stanciu
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005764:Gastroesophageal Reflux / Q000097:blood* / Q000382:microbiology; D016481:Helicobacter Infections / Q000097:blood* / Q000150:complications*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007155:Immunologic Factors / Q000097:blood*; D008297:Male; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G; D007155:Immunologic Factors