title: Contralateral acupuncture versus ipsilateral acupuncture in the rehabilitation of post-stroke hemiplegic patients: a systematic review.
abstract: BACKGROUND
  Contralateral acupuncture (CAT) involves inserting needles in the meridian on the side opposite the disease location and is often used in post-stroke rehabilitation. The aim of this systematic review is to summarize and critically evaluate the evidence for and against the effectiveness of CAT for post-stroke rehabilitation as compared to ipsilateral acupuncture (IAT).
  
  
  METHODS
  Seventeen databases were searched from their inceptions through June 2010. Prospective clinical trials were included if CAT was tested as the sole treatment or as an adjunct to other treatments for post-stroke rehabilitation and compared to IAT.
  
  
  RESULTS
  Eight randomized clinical trials (RCTs) met our inclusion criteria. Four of them reported favorable effects of CAT compared to IAT for at least one outcome. A meta-analysis showed superior effects of CAT compared to IAT on recovery rate (n = 361; risk ratio (RR), 1.12; 95% confidence intervals (CIs), 1.04 to 1.22, P = 0.005). Subgroup analysis also showed favorable effects of using CAT on patients with cerebral infarction (n = 261; RR, 1.15; 95% CIs, 1.04 to 1.27, P = 0.006). Further analysis including patients with cerebral infarction and intracranial hemorrhage, however, failed to show these advantages (n = 100; RR, 1.11; 95% CIs, 0.85 to 1.46, P = 0.43).
  
  
  CONCLUSIONS
  The results of our systematic review and meta-analysis suggest that there is limited evidence for CAT being superior to IAT in the treatment of cerebral infarction. The total number of RCTs included in our analysis was low, however, and the RCTs included had a high risk of bias. Future RCTs appear to be warranted.
authors.affiliation: Department of Korean Internal Medicine, Dongguk University Ilsan Hospital, Goyang, South Korea.
authors.forename: Mi-kyung
authors.initials: MK
authors.lastname: Kim
authors.forename: Tae-Young
authors.initials: TY
authors.lastname: Choi
authors.forename: Myeong Soo
authors.initials: MS
authors.lastname: Lee
authors.forename: Hyangsook
authors.initials: H
authors.lastname: Lee
authors.forename: Chang-ho
authors.initials: CH
authors.lastname: Han
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000379:methods*; D002544:Cerebral Infarction / Q000534:rehabilitation; D006429:Hemiplegia / Q000209:etiology / Q000534:rehabilitation*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000534:rehabilitation; D016740:Meridians; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome