[Diamond-Blackfan anemia. Case report].
Diamond-blakfan anemia (DBA) is a rare condition in pediatric pathology, with more than 500 cases described in literature. It is a congenital eritroblastopenia, with AD/AR/ X-linkage inheritance, 90% were diagnosed by one year of age. Physical appearances were abnormal only in 29%. The current recommendations are corticosteroids, with suportive treatment and bone marrow transplantation. In general, DBA remains a single cytopenia. Long term prognosis remains uncertain, DBA is a preleukemia condition. We present two cases that we took care of in our clinics.
Salariu
Magdalena
M
Universitatea de Medică şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Disciplina de Pediatrie.
Miron
Ingrid
I
Tansanu
I
I
D000293:Adolescent; D029503:Anemia, Diamond-Blackfan / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D001565:Benzoates / Q000627:therapeutic use; D001803:Blood Transfusion; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis; D000077588:Deferasirox; D003676:Deferoxamine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006529:Hepatomegaly / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007502:Iron Chelating Agents / Q000627:therapeutic use; D008297:Male; D011379:Prognosis; D017262:Siderophores / Q000627:therapeutic use; D013163:Splenomegaly / Q000175:diagnosis; D045165:Testosterone Congeners / Q000627:therapeutic use; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use
D001565:Benzoates; D005938:Glucocorticoids; D007502:Iron Chelating Agents; D017262:Siderophores; D045165:Testosterone Congeners; D014230:Triazoles; D003676:Deferoxamine; D000077588:Deferasirox