Cochlear otosclerosis.
OBJECTIVE
The aim of this study is to summarize current advances in research and clinical aspects of cochlear otosclerosis.


RESULTS
Recent studies have revealed that otosclerosis is a process of bone remodeling that is unique to the otic capsule only. Even though no obvious bone remodeling is seen in the otic capsule under normal conditions, remodeling starts when some molecular factors trigger the capsule in certain patients who have genetic and/or environmental tendencies.


CONCLUSIONS
Cochlear otosclerosis is defined as otosclerosis located in the otic capsule involving the cochlear endosteum and causing sensorineural hearing loss or mixed-type hearing loss. It has been clearly shown that, when otosclerosis is sufficiently severe to involve the cochlear endosteum, it usually fixes the stapes as well.
Cureoglu
Sebahattin
S
Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota, USA.
Baylan
Muzeyyen Y
MY
Paparella
Michael M
MM
D016723:Bone Remodeling; D003051:Cochlea; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D010040:Otosclerosis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy