Synthesis and antioxidant activity of quinolinobenzothiazinones.
A new series of structurally diverse quinolinobenzothiazinones has been synthesized with the annulation of heterocyclic structural pharmacophores. The synthesized quinolinobenzothiazinones have been evaluated for their antioxidant (LPO & GSH) and radical scavenging activities (DPPH and ABTS assays).
Kumar
M
M
Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur 302055, Rajasthan, India. mahendrakpathak@gmail.com
Sharma
Kshitija
K
Samarth
R M
RM
Kumar
A
A
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D052160:Benzothiazoles / Q000378:metabolism; D001713:Biphenyl Compounds / Q000378:metabolism; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D051379:Mice; D010851:Picrates / Q000378:metabolism; D011804:Quinolines / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D013451:Sulfonic Acids / Q000378:metabolism; D013843:Thiazines / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
C446962:1,4-benzothiazine; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D010851:Picrates; D011804:Quinolines; D013451:Sulfonic Acids; D013843:Thiazines; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl