title: Optical quality in eyes implanted with aspheric and spherical intraocular lenses assessed by NIDEK OPD-Scan: a randomized, bilateral, clinical trial.
abstract: OBJECTIVE
  To determine whether implantation of an intraocular lens (IOL) with an aspheric surface (Akreos AO, Bausch & Lomb Inc) results in reduced ocular aberrations (spherical aberration) and improved Strehl ratio and modulation transfer function (MTF) after cataract surgery.
  
  
  METHODS
  In an intraindividual, randomized, double-masked, prospective study of 50 eyes (25 patients) with bilateral cataract, an IOL with modified anterior and posterior surfaces (Akreos AO) was implanted in one eye and a biconvex IOL with spherical surfaces (Akreos Fit, Bausch & Lomb Inc) implanted in the fellow eye. Ocular aberrations, Strehl ratio, and MTF curve with 4.5-, 5.0-, and 6.0-mm pupils were measured with a NIDEK OPD-Scan dynamic retinoscopy aberrometer 3 months after surgery. Uncorrected and corrected distance visual acuity (UDVA and CDVA, respectively) were also measured.
  
  
  RESULTS
  No statistically significant difference was noted between eyes in postoperative UDVA and CDVA at 1 month. At 3 months, the Akreos AO IOL group obtained statistically significant lower values of higher order and spherical aberrations with 4.5-, 5.0-, and 6.0-mm pupil diameters than the Akreos Fit IOL group (P<.05). The value of Strehl ratio was statistically significantly higher in eyes with the Akreos AO IOL for 4.5- and 6.0-mm pupils (P<.05). The MTF curve was better in the Akreos AO IOL group in 4.5-, 5.0-, and 6.0-mm pupils (P<.05).
  
  
  CONCLUSIONS
  The aspheric Akreos AO IOL induced significantly less spherical aberration than the Akreos Fit IOL for 4.5-, 5.0-, and 6.0-mm pupils. Modulation transfer function and Strehl ratio were also better in eyes implanted with the Akreos AO IOL than the Akreos Fit.
authors.affiliation: Ophthalmology Department, University of São Paulo, Brazil. marconysanthiago@hotmail.com
authors.forename: Marcony R
authors.initials: MR
authors.lastname: Santhiago
authors.forename: Marcelo V
authors.initials: MV
authors.lastname: Netto
authors.forename: Jackson
authors.initials: J
authors.lastname: Barreto
authors.forename: Beatriz A F
authors.initials: BA
authors.lastname: Gomes
authors.forename: Cristiane D
authors.initials: CD
authors.lastname: Oliveira
authors.forename: Newton
authors.initials: N
authors.lastname: Kara-Junior
mesh_terms: D057128:Aberrometry / Q000295:instrumentation / Q000379:methods*; D000368:Aged; D057108:Corneal Wavefront Aberration / Q000503:physiopathology / Q000517:prevention & control*; D004311:Double-Blind Method; D005260:Female; D007839:Functional Laterality; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D011680:Pupil / Q000502:physiology; D042262:Retinoscopy; D014792:Visual Acuity / Q000502:physiology