Pandemic (H1N1) 2009 virus and Down syndrome patients.
We compared prevalence of hospitalization, endotracheal intubation, and death among case-patients with and without Down syndrome during pandemic (H1N1) 2009 in Mexico. Likelihoods of hospitalization, intubation, and death were 16-fold, 8-fold, and 335-fold greater, respectively, for patients with Down syndrome. Vaccination and early antiviral drug treatment are recommended during such epidemics.
Pérez-Padilla
Rogelio
R
National Institute of Respiratory Diseases, Mexico City, Mexico. perezpad@gmail.com
Fernández
Rosario
R
García-Sancho
Cecilia
C
Franco-Marina
Francisco
F
Aburto
Octavio
O
López-Gatell
Hugo
H
Bojórquez
Ietza
I
D000293:Adolescent; D000328:Adult; D002648:Child; D004314:Down Syndrome / Q000453:epidemiology / Q000821:virology*; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000453:epidemiology / Q000821:virology; D008297:Male; D058873:Pandemics; D055815:Young Adult