title: Synthesis of novel tripodal-benzimidazole from 2,4,6-tris(p-formylphenoxy)-1,3,5-triazine: structural, electrochemical and antimicrobial studies.
abstract: Four new tripodal-benzimidazole derivatives were synthesized by Schiff base reaction between 2,4,6-tris(p-formylphenoxy)-1,3,5-triazine (TRIPOD) and different diamine derivatives. The structures of the obtained compounds were identified by FT-IR, (1)H NMR, (13)C NMR and UV-vis spectral data, thermal analysis and elemental analysis. Electrochemical behaviors of the compounds were studied by cyclic voltammetry in DMF including 0.1 M [NBu(4)] [PF(6)]. The voltammograms showed peaks having similar characteristics except tripodal-benzimidazole including -NO(2) derivative. In addition, their antimicrobial activities were evaluated by using the standard disk diffusion method in dimethylformamide media. The activities were determined against 4 bacteria cultures by comparing to those of gentamycin.
authors.affiliation: Department of Chemistry, Faculty of Science, Selcuk University, 42031 Konya, Turkey. zerdemkoc@gmail.com
authors.forename: Ziya Erdem
authors.initials: ZE
authors.lastname: Koc
authors.forename: Haluk
authors.initials: H
authors.lastname: Bingol
authors.forename: Ahmet O
authors.initials: AO
authors.lastname: Saf
authors.forename: Emrah
authors.initials: E
authors.lastname: Torlak
authors.forename: Ahmet
authors.initials: A
authors.lastname: Coskun
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000166:cytology / Q000187:drug effects*; D001562:Benzimidazoles / Q000737:chemistry* / Q000494:pharmacology; D003959:Diamines / Q000737:chemistry; D004563:Electrochemistry; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012545:Schiff Bases / Q000737:chemistry; D013329:Structure-Activity Relationship; D014227:Triazines / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D003959:Diamines; D012545:Schiff Bases; D014227:Triazines