title: Prospective follow-up of female sexual function after vaginal surgery for pelvic organ prolapse using transobturator mesh implants.
abstract: BACKGROUND
  Although the use of transobturator mesh implants for pelvic organ prolapse repair has been shown to be safe and effective, concern exists that the presence of prosthetic material in the vagina may adversely affect sexual function.
  
  
  OBJECTIVE
  To evaluate the impact of transobturator mesh implantation on sexual function using validated questionnaire.
  
  
  METHODS
  Female Sexual Function Index (FSFI), a validated 19-item questionnaire that assesses six domains of sexual function (desire, arousal, lubrication, orgasm, satisfaction, and pain), was used. The questionnaire was administered preoperatively, and at 3, 6, 12, and 24 months postoperatively. Clinical data were also recorded at each time point.
  
  
  METHODS
  Prospective nonrandomized study including 96 women with pelvic organ prolapse (cystocele, rectocele, vault prolapse). Transvaginal anterior or posterior wall repair using transobturator mesh implants with or without concomitant transobturator sling procedure.
  
  
  RESULTS
  Mean age was 51.4 ± 5.2 years. Mean operating time was 47.6 ± 23.4 minutes, and the mean hospitalization period was 3.8 ± 1.6 days. After initial decrease during the first 3 months, patients experienced a steady improvement in their sexual function. At 24 months postoperatively, the total mean FSFI score reached significantly higher values compared to the baseline (P = 0.023). Furthermore, pain-free intercourse improved during the follow-up reaching mean score of 4.27 ± 0.79 (P < 0.05) after 2 years. Pelvic floor examination at 2 years follow-up showed excellent surgical results with only 3.1% of the patients presenting with stage II vaginal wall prolapse.
  
  
  CONCLUSIONS
  Surgical repair of symptomatic pelvic organ prolapse using mesh implants results in improvement of major parameters of sexual function. A worsening in pain with intercourse during the initial months postoperatively lessens after 3 months as healing is completed.
authors.affiliation: University Medical School of Halle/Wittenberg, Clinic for Urology and Kidney Transplantation Centre, Wittenberg, Germany. rhoda@ucsd.edu
authors.forename: M R
authors.initials: MR
authors.lastname: Hoda
authors.forename: Sigrid
authors.initials: S
authors.lastname: Wagner
authors.forename: Francesco
authors.initials: F
authors.lastname: Greco
authors.forename: Hans
authors.initials: H
authors.lastname: Heynemann
authors.forename: Paolo
authors.initials: P
authors.lastname: Fornara
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D012725:Sexual Behavior; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014621:Vagina / Q000601:surgery*