title: [Interstitial lung disease associated with combination chemotherapy of oxaliplatin, 5-fluorouracil, and leucovorin].
abstract: Oxaliplatin with 5-fluorouracil plus leucovorin (FOLFOX) has become the standard treatment in patients with colorectal cancer. Among known toxicities induced by oxaliplatin, hematological, gastrointestinal and neurological toxicities are common. However, acute pulmonary toxicity associated with oxaliplatin is unusual. One case of interstitial lung disease associated with the FOLFOX protocol is reported here.
authors.affiliation: Department of Internal Medicine, Sun General Hospital, Daejeon, Korea.
authors.forename: Sul
authors.initials: S
authors.lastname: Park
authors.forename: Jae Jin
authors.initials: JJ
authors.lastname: Jung
authors.forename: Goeng Bae
authors.initials: GB
authors.lastname: Kim
authors.forename: Hyung Sik
authors.initials: HS
authors.lastname: Yoon
authors.forename: Sang Hun
authors.initials: SH
authors.lastname: Ko
authors.forename: Jae Ee
authors.initials: JE
authors.lastname: Ko
authors.forename: Yeun Seun
authors.initials: YS
authors.lastname: Lee
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols; D015179:Colorectal Neoplasms / Q000188:drug therapy; D005472:Fluorouracil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects* / Q000627:therapeutic use; D017563:Lung Diseases, Interstitial / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D009944:Organoplatinum Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D000077150:Oxaliplatin; D011859:Radiography
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D002955:Leucovorin; D005472:Fluorouracil