title: CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy.
abstract: We have studied the photodynamic properties of novel CdTe quantum dots-methylene blue hybrid photosensitizer. Absorption spectroscopy, photoluminescence spectroscopy, and fluorescence lifetime imaging of this system reveal efficient charge transfer between nanocrystals and the methylene blue dye. Near-infrared photoluminescence measurements provide evidence for an increased efficiency of singlet oxygen production by the methylene blue dye. In vitro studies on the growth of HepG2 and HeLa cancerous cells were also performed, they point toward an improvement in the cell kill efficiency for the methylene blue-semiconductor nanocrystals hybrid system.
authors.affiliation: School of Physics and CRANN Research Centre, Trinity College, Dublin 2, Ireland. Yury.Rakovich@tcd.ie.
authors.forename: Aliaksandra
authors.initials: A
authors.lastname: Rakovich
authors.forename: Diana
authors.initials: D
authors.lastname: Savateeva
authors.forename: Tatsiana
authors.initials: T
authors.lastname: Rakovich
authors.forename: John F
authors.initials: JF
authors.lastname: Donegan
authors.forename: Yury P
authors.initials: YP
authors.lastname: Rakovich
authors.forename: Vincent
authors.initials: V
authors.lastname: Kelly
authors.forename: Vladimir
authors.initials: V
authors.lastname: Lesnyak
authors.forename: Alexander
authors.initials: A
authors.lastname: Eychmüller