Are insulin resistance index, IGF-1 and metabolic syndrome components correlates with severe preeclampsia?
OBJECTIVE
Analyse the relation between insulin resistance and severe preeclampsia (SPE).


METHODS
Case control study paired by body mass index and gestational age; including 16 patients with severe SPE and 16 normotensive controls. Insulin resistance was assessed through the HOMA-IR and QUICKI-IS indexes.


RESULTS
There was no significant difference between the groups regarding the HOMA-IR and QUICKI-IS indexes and HDL cholesterol. Triglyceride levels were higher and the IGF-1 was lower in the SPE group than in the control group.


CONCLUSIONS
There were no differences in the insulin resitance indexes between the group with SPE and normal controls.
Valério
Edimárlei Gonsales
EG
Programa de Pós-Graduação em Medicina: Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, RS, Brazil. edimarleigv@terra.com.br
Müller
Ana Lúcia Letti
AL
Martins-Costa
Sérgio Hofmeister
SH
Lopes Ramos
José Geraldo
JG
Rodini
Gustavo
G
D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D024821:Metabolic Syndrome / Q000378:metabolism* / Q000503:physiopathology; D011225:Pre-Eclampsia / Q000378:metabolism* / Q000503:physiopathology; D011247:Pregnancy; D012720:Severity of Illness Index
D001786:Blood Glucose; D007334:Insulin-Like Growth Factor I