title: The biomechanical contribution of varying posterior constructs following anterior thoracolumbar corpectomy and reconstruction.
abstract: OBJECTIVE
  Thoracolumbar corpectomy is a procedure commonly required for the treatment of various pathologies involving the vertebral body. Although the biomechanical stability of anterior reconstruction with plating has been studied, the biomechanical contribution of posterior instrumentation to anterior constructs remains unknown. The purpose of this study was to evaluate biomechanical stability after anterior thoracolumbar corpectomy and reconstruction with varying posterior constructs by measuring bending stiffness for the axes of flexion/extension, lateral bending, and axial rotation.
  
  
  METHODS
  Seven fresh human cadaveric thoracolumbar spine specimens were tested intact and after L-1 corpectomy and strut grafting with 4 different fixation techniques: anterior plating with bilateral, ipsilateral, contralateral, or no posterior pedicle screw fixation. Bending stiffness was measured under pure moments of +/- 5 Nm in flexion/extension, lateral bending, and axial rotation, while maintaining an axial preload of 100 N with a follower load. Results for each configuration were normalized to the intact condition and were compared using ANOVA.
  
  
  RESULTS
  Spinal constructs with anterior-posterior spinal reconstruction and bilateral posterior pedicle screws were significantly stiffer in flexion/extension than intact spines or spines with anterior plating alone. Anterior plating without pedicle screw fixation was no different from the intact spine in flexion/extension and lateral bending. All constructs had reduced stiffness in axial rotation compared with intact spines.
  
  
  CONCLUSIONS
  The addition of bilateral posterior instrumentation provided significantly greater stability at the thoracolumbar junction after total corpectomy than anterior plating and should be considered in cases in which anterior column reconstruction alone may be insufficient. In cases precluding bilateral posterior fixation, unilateral posterior instrumentation may provide some additional stability.
authors.affiliation: Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Frank S
authors.initials: FS
authors.lastname: Bishop
authors.forename: Mical M
authors.initials: MM
authors.lastname: Samuelson
authors.forename: Michael A
authors.initials: MA
authors.lastname: Finn
authors.forename: Kent N
authors.initials: KN
authors.lastname: Bachus
authors.forename: Darrel S
authors.initials: DS
authors.lastname: Brodke
authors.forename: Meic H
authors.initials: MH
authors.lastname: Schmidt
mesh_terms: D001696:Biomechanical Phenomena; D001860:Bone Plates; D001863:Bone Screws; D002102:Cadaver; D006801:Humans; D007403:Intervertebral Disc / Q000502:physiology / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000502:physiology / Q000601:surgery*; D016059:Range of Motion, Articular; D019651:Plastic Surgery Procedures / Q000295:instrumentation / Q000379:methods*; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D013904:Thoracic Vertebrae / Q000502:physiology / Q000601:surgery*; D054159:Torsion, Mechanical; D016474:Weight-Bearing