Novel 6,12-disubstituted chrysene as potent anticancer agent: synthesis, in vitro and in vivo study.
We describe herein the synthesis of novel 6,12-distributed chrysene as potent anticancer agents. In vitro and in vivo studies are also reported here.
Banik
Bimal K
BK
The University of Texas-Pan American, Department of Chemistry, 1201 West University Drive, Edinburg, TX 78539, USA. banik@panam.edu
Becker
Frederick F
FF
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002911:Chrysenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D051379:Mice; D010051:Ovarian Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents; D002911:Chrysenes; C031180:chrysene