Accuracy of a probabilistic record linkage strategy applied to identify deaths among cases reported to the Brazilian AIDS surveillance database.
Since record linkage errors can bias measures of disease occurrence and association, it is important to assess their accuracy. The aim of this study is to assess the accuracy of a multiple pass probabilistic record linkage strategy to identify deaths among persons reported to the Brazilian AIDS surveillance database. An HIV/AIDS national surveillance database (N=559,442) was linked to a total of 6,444,822 deaths registered (all causes) in the Brazilian mortality database. To estimate standard measures of accuracy, we selected all AIDS cases with a date of death registered in the surveillance database from 2002 to 2005 (N=19,750) and 38,675 cases known to be alive in 2006. The linkage strategy presented a sensitivity of 87.6% (95%CI: 87.1-88.2), a specificity of 99.6% (95%CI: 99.6-99.7), and a positive predictive value of 99.2% (95%CI: 99.1-99.3). We observed a small variation in the validity measures according to some putative predictors of mortality. Our findings suggest that even large and heterogeneous databases can be linked with a satisfactory accuracy.
Fonseca
Maria Goretti Pereira
MG
Diretoria Regional de Brasília, Fundação Oswaldo Cruz, Brasília, Brazil. gorettifonseca@fiocruz.br
Coeli
Cláudia Medina
CM
de Fátima de Araújo Lucena
Francisca
F
Veloso
Valdilea Gonçalves
VG
Carvalho
Marilia Sá
MS
D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D016208:Databases, Factual / Q000592:standards*; D018563:Disease Notification / Q000592:standards; D005260:Female; D006302:Health Services Research / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008498:Medical Record Linkage / Q000592:standards*; D008875:Middle Aged; D011336:Probability; D015203:Reproducibility of Results; D055815:Young Adult