title: Cardiovascular risk factors associated with migraine among the elderly with a low income: the Sao Paulo Ageing & Health Study (SPAH).
abstract: BACKGROUND
  To investigate the association between cardiovascular risk-factor profile and migraine in the elderly, we evaluated a population sample of ageing men and women (65 years or more) living in a low-income area in the city of São Paulo, Brazil.
  
  
  METHODS
  We investigated migraine status and cardiovascular profile from a baseline of 1450 participants (65-102 years of age) of the São Paulo Ageing & Health Study (SPAH), a longitudinal population-based study with low-income elderly in Brazil. The following age and sex-adjusted cardiovascular risk factors were analyzed: blood pressure, pulse pressure, serum total and high-density lipoprotein cholesterol, body mass index, smoking, history of hypertension, diabetes and the 10-year risk of myocardial infarction or coronary heart disease death based on the Framingham Risk Score.
  
  
  RESULTS
  The overall prevalence of migraine was 11.4%, and it was 3 times more frequent among women than men (15.3% vs 5.4%; P < 0.0001). Migraineurs were younger than non-migraineurs (mean age 70.6 years vs 72.1 years; P = 0.001, respectively). There was no statistically significant difference regarding the cardiovascular risk-factor profile after adjustment for age and sex among migraineurs and non-migraineurs. Only a decrease in the risk of hypertension among women (OR 0.58; 95% CI 0.38-0.90; P = 0.01) was also observed even after adjustment for age.
  
  
  CONCLUSIONS
  Overall, we did not find a worse cardiovascular risk profile among elderly migraineurs. An inverse association between hypertension and migraine in women warrants further investigation.
authors.affiliation: University of São Paulo, Av. Lineu Prestes 2565, São Paulo, SP, Brazil. isabensenor@hu.usp.br
authors.forename: Isabela M
authors.initials: IM
authors.lastname: Benseñor
authors.forename: Alessandra C
authors.initials: AC
authors.lastname: Goulart
authors.forename: Paulo A
authors.initials: PA
authors.lastname: Lotufo
authors.forename: Paulo R
authors.initials: PR
authors.lastname: Menezes
authors.forename: Márcia
authors.initials: M
authors.lastname: Scazufca
mesh_terms: D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000150:complications* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000150:complications* / Q000453:epidemiology*; D011203:Poverty; D015995:Prevalence; D012307:Risk Factors