title: Fibrous cortical defect (nonossifying fibroma) of the mandibular ramus: report of 2 cases.
abstract: Fibrous cortical defect, also known as metaphyseal fibrous defect and nonossifying fibroma, among other terms, is a benign, non-neoplastic proliferative process that is relatively common in the long bones of skeletally immature adolescents. Although the lesion is thought to be a developmental abnormality or defect, the exact etiopathogenesis is largely unknown. The lesion has a limited growth potential and good treatment outcome. This process is very rare in the gnathic bones, and only a few sporadic case reports are documented. This article presents the clinicopathologic features of 2 additional cases and reviews the relevant literature in attempt to identify key features and facilitate rendering definitive diagnosis for this rare entity.
authors.affiliation: Division of Oral and Maxillofacial Pathology, Department of Oral Health and Diagnostic Sciences, School of Dentistry, The Medical College of Georgia, Augusta, GA 30912, USA. rabdelsa@mail.mcg.edu
authors.forename: Rafik A
authors.initials: RA
authors.lastname: Abdelsayed
authors.forename: Suash
authors.initials: S
authors.lastname: Sharma
authors.forename: Henry
authors.initials: H
authors.lastname: Ferguson
mesh_terms: D000293:Adolescent; D000328:Adult; D001848:Bone Diseases, Developmental / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000473:pathology*