title: A new tandem mass spectrometer for photofragment spectroscopy of cold, gas-phase molecular ions.
abstract: We present here the design of a new tandem mass spectrometer that combines an electrospray ion source with a cryogenically cooled ion trap for spectroscopic studies of cold, gas-phase ions. The ability to generate large ions in the gas phase without fragmentation, cool them to approximately 10 K in an ion trap, and perform photofragment spectroscopy opens up new possibilities for spectroscopic characterization of large biomolecular ions. The incorporation of an ion funnel, together with a number of small enhancements, significantly improves the sensitivity, signal stability, and ease of use compared with the previous instrument built in our laboratory.
authors.affiliation: Laboratoire de Chimie Physique Moléculaire, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCPM, Station 6, CH-1015 Lausanne, Switzerland.
authors.forename: Annette
authors.initials: A
authors.lastname: Svendsen
authors.forename: Ulrich J
authors.initials: UJ
authors.lastname: Lorenz
authors.forename: Oleg V
authors.initials: OV
authors.lastname: Boyarkin
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Rizzo
mesh_terms: D003080:Cold Temperature; D004581:Electronics; D004867:Equipment Design; D005740:Gases / Q000737:chemistry*; D036103:Nanotechnology; D013057:Spectrum Analysis / Q000295:instrumentation*; D053719:Tandem Mass Spectrometry / Q000295:instrumentation*
chemical_list: D005740:Gases