Atopic dermatitis and keratoconjunctivitis.
Atopic dermatitis, a chronic disease seen by allergist-immunologists, has both dermatologic and ocular manifestations. The ocular component is often disproportionately higher than the dermatologic disease. Even if skin abnormalities seem well controlled, these patients require ophthalmic evaluation. Atopic keratoconjunctivitis in atopic dermatitis patients is characterized by acute exacerbations and requires maintenance therapy for long-term control. Future studies will continue to emphasize the use of steroid-sparing, immunomodulating agents that have the potential to provide long-lasting anti-inflammatory control with a more favorable side-effect profile.
Bielory
Brett
B
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th Street, Miami, FL 33136, USA.
Bielory
Leonard
L
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D001762:Blepharitis; D016572:Cyclosporine / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D056747:Immunomodulation; D007637:Keratoconjunctivitis; D012307:Risk Factors; D016559:Tacrolimus / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D016572:Cyclosporine; D016559:Tacrolimus