Mitochondrial matrix reloaded with RNA.
Although mitochondrial biogenesis requires the import of specific RNAs, the pathways and cellular machineries involved are only poorly understood. Wang et al. (2010) now find that polynucleotide phosphorylase in the intermembrane space of mammalian mitochondria facilitates import of several RNAs into the mitochondrial matrix.
Endo
Toshiya
T
Department of Chemistry, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan. endo@biochem.chem.nagoya-u.ac.jp
Yamano
Koji
K
Yoshihisa
Tohru
T