[Studies on the chemical constituents from aerial parts of Gynura divaricata].
OBJECTIVE
To study the chemical constituents from aerial parts of Gynura divaricata.


METHODS
The constituents were isolated on silica gel column chromatography, preparative TLC and Sephadex LH-20 column chromatography, identified by physicochemical properties and the structures were elucidated by spectral analysis.


RESULTS
10 compounds were isolated and identified as 2-(1', 2', 3', 4'-tetrahydroxybutyl)-6-(2", 3", 4"-trihydroxybutyl)-pyrazine (1), 2-(1', 2', 3', 4'-tetrahydroxybutyl)-5-(2", 3", 4"-trihydroxybutyl) -pyrazine (2), nicotinic acid (3), 5-hydroxy-picolinic acid(4), methyl-5-hydroxy-2- pyridinecarboxylate (5), adenosine (6), uridine (7), stigmasterol-5-O- beta-D-glucoside (8), dibutyl terephthalate (9), methyl chlorogenate (10).


CONCLUSIONS
Compounds 1, 2, 5, 9, 10 are obtained from this genus for the first time, Compounds 3, 4 are obtained from this plant for the first time.
Chen
Lei
L
Department of Pharmacy, Fuzhou General Hospital of Nanjing Military Region, Fuzhou 350025, China. chen1974lei@sina.com
Song
Zeng-Yan
ZY
Wang
Jin-Jiang
JJ
Song
Hong-Tao
HT
Zhang
Guo-Gang
GG
Wang
Jin-Hui
JH
D000241:Adenosine / Q000737:chemistry / Q000302:isolation & purification; D019659:Asteraceae / Q000737:chemistry*; D002726:Chlorogenic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009525:Niacin / Q000737:chemistry / Q000302:isolation & purification*; D010848:Picolinic Acids / Q000737:chemistry / Q000302:isolation & purification*; D035261:Plant Components, Aerial / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D014529:Uridine / Q000737:chemistry / Q000302:isolation & purification
C550634:4-hydroxy-2,3,4,5-tetrahydro-2-dipicolinic acid; D010848:Picolinic Acids; D009525:Niacin; D002726:Chlorogenic Acid; C417238:methyl chlorogenate; D000241:Adenosine; D014529:Uridine