Polymer-supported pentaethylene glycol as a facile heterogeneous catalyst for nucleophilic fluorination.
Polymer-supported pentaethylene glycols (PSpentaEG) as promising catalysts for nucleophilic fluorination with alkali metal fluoride (MF) could significantly enhance the nucleophilicity of MF and provide simple purification and recycling in the reaction. Furthermore, by their synergistic effect, the combination of PSpentaEG and a tert-alcohol media system showed tremendous efficiency in the fluorination of base-sensitive substrates such as sec-alkyl halide.
Jadhav
Vinod H
VH
Department of Nuclear Medicine, Cyclotron Research Center, Chonbuk National University Medical School, Jeonju, Jeonbuk 561-712, Korea.
Jang
Seung Ho
SH
Jeong
Hwan-Jeong
HJ
Lim
Seok Tae
ST
Sohn
Myung-Hee
MH
Chi
Dae Yoon
DY
Kim
Dong Wook
DW
D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006018:Glycols / Q000737:chemistry*; D054879:Halogenation; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*
D006018:Glycols; D011108:Polymers