title: Bilateral pallidal stimulation for x-linked dystonia parkinsonism.
abstract: OBJECTIVE
  To report the clinical benefits of bilateral deep brain stimulation (DBS) of the globus pallidus internus (GPi) in a patient with X-linked dystonia parkinsonism (XDP).
  
  
  METHODS
  Case report.
  
  
  METHODS
  Tertiary referral center. Patient A 40-year-old Filipino man with genetically confirmed XDP and severely disabling generalized dystonia. Intervention Bilateral GPi DBS.
  
  
  METHODS
  The primary outcome measures were the Burke-Fahn-Marsden Dystonia Scale (BFMDS) severity and disability scores, and the secondary outcome measure was the Unified Parkinson Disease Rating Scores.
  
  
  RESULTS
  At the 1-year postoperative follow-up, there was 80.4% improvement in the BFMDS severity score and 66.7% improvement in the BFMDS disability score.
  
  
  CONCLUSIONS
  Bilateral GPi DBS seems to be very effective in improving dystonia in XDP.
authors.affiliation: Movement Disorders Centre, Toronto Western Hospital, 399 Bathurst St, McL7-402, Toronto, Ontario, Canada, M5T 2S8. elena.moro@uhn.on.ca.
authors.forename: Pettarusp M
authors.initials: PM
authors.lastname: Wadia
authors.forename: Shen-Yang
authors.initials: SY
authors.lastname: Lim
authors.forename: Andres M
authors.initials: AM
authors.lastname: Lozano
authors.forename: John R
authors.initials: JR
authors.lastname: Adams
authors.forename: Yu-Yan
authors.initials: YY
authors.lastname: Poon
authors.forename: Cristina V
authors.initials: CV
authors.lastname: Torres Diaz
authors.forename: Cristina Torres
authors.initials: CT
authors.lastname: Diaz
authors.forename: Elena
authors.initials: E
authors.lastname: Moro
mesh_terms: D000328:Adult; D046690:Deep Brain Stimulation / Q000379:methods*; D004421:Dystonia / Q000150:complications / Q000235:genetics / Q000628:therapy*; D040181:Genetic Diseases, X-Linked / Q000150:complications / Q000628:therapy*; D005917:Globus Pallidus / Q000502:physiology; D006801:Humans; D008297:Male; D020734:Parkinsonian Disorders / Q000150:complications / Q000235:genetics / Q000628:therapy*; D012720:Severity of Illness Index