title: [The analysis of epidemiology, clinical symptoms, serological tests in the course of borreliosis].
abstract: BACKGROUND
  Lyme disease is an animal-borne disease, caused by spirochetes of the Borrelia burgdorferi (Bb). The infection is transmitted by ticks of the Ixodes ricinus species. Humans are infected through a tick bite to the skin. The aim of the study was evaluation of epidemiology, symptoms and serologic factors in Lyme disease.
  
  
  METHODS
  We have enrolled 39 patients from Malopołska region in the study treated for Lyme borreliosis. History of tick biting, clinical signs and symptoms and serological tests were evaluated.
  
  
  RESULTS
  The most common symptoms were headaches and pain of the large joints. Patients with untreated erithema migrans (EM) more often developed symptoms from nervous system (83%) than joints (54%). We found abnormalities which confirmed inflammation in CSF in 24.3% of patients. Patients with positive IgG antibodies against Bb in CSF and confirmed their intrathecal synthesis had never had EM in the past.
  
  
  CONCLUSIONS
  There is low percentage of the patients who were treated due to EM. Patients with untreated EM more often developed symptoms from nervous system than joints. The most common symptoms among our patients were headaches and pain of large joints.
authors.affiliation: Klinika Chorób Zakaźnych, Katedry Gastroenterologii, Hepatologii i Chorób Zakaźnych, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie. gbiesiada@op.pl
authors.forename: Grazyna
authors.initials: G
authors.lastname: Biesiada
authors.forename: Jacek
authors.initials: J
authors.lastname: Czepiel
authors.forename: Maciej
authors.initials: M
authors.lastname: Leśniak
authors.forename: Aleksander
authors.initials: A
authors.lastname: Garlicki
authors.forename: Tomasz
authors.initials: T
authors.lastname: Mach
mesh_terms: D000328:Adult; D018771:Arthralgia / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D015994:Incidence; D008193:Lyme Disease / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012698:Serologic Tests
chemical_list: D007074:Immunoglobulin G