title: Acute infectious pseudoaneurysm of the descending thoracic aorta and review of infectious aortitis.
abstract: Thoracic aortic wall disruptions may occur secondary to trauma, surgical interventions, infection, or autoimmune or idiopathic inflammatory disorders. Such vessel wall disruption can lead to aortic dissections, aneurysm development, or more commonly, pseudoaneurysm (PSA) formation. Although aortic wall infections as an antecedent to mycotic aneurysms have been recognized since the 17th century, there has been a temporal evolution in the development of this disease. Prior to the antibiotic era they were commonly associated with endocarditis or syphilis. More recently, however, they are associated with infection of a damaged atherosclerotic area of the aorta and secondary hematogenous or contiguous seeding. We report the first case of the rapid development of a pseudoaneurysm in the descending thoracic aorta attributable to an infection of a contiguous esophageal duplication cyst by a diagnostic esophageal ultrasound (EUS) fine-needle aspiration. A literature review of mycotic thoracic aortic aneurysms and pseudoaneurysms is also presented.
authors.affiliation: Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA. mcevasco@partners.org.
authors.forename: Marisa
authors.initials: M
authors.lastname: Cevasco
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Menard
authors.forename: Richard
authors.initials: R
authors.lastname: Bafford
authors.forename: Ciaran J
authors.initials: CJ
authors.lastname: McNamee
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D000785:Aneurysm, Infected / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D001025:Aortitis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D044963:Biopsy, Fine-Needle; D019917:Blood Vessel Prosthesis Implantation; D003646:Debridement; D016145:Endoscopy, Digestive System; D019160:Endosonography; D004934:Esophageal Cyst / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D005260:Female; D006801:Humans; D007778:Lactobacillus / Q000302:isolation & purification; D018810:Magnetic Resonance Angiography; D013524:Surgical Flaps; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents