title: A rare case of seronegative neurobrucellosis.
abstract: Neurobrucellosis is one of the complications of brucellosis. We report a rare case of a 17-year-old girl with seronegative neurobrucellosis and depression and diplopia. Results of agglutination tests for Brucella both in serum and CSF were negative. Diagnosis was made only by positive culture of Brucella mellitensis with inoculation of the patient's cerebrospinal fluid in a BACTEC 9050 System. The patient was successfully treated using ceftriaxone, doxycycline and rifampicin therapy for six months.
authors.affiliation: Harran University, Infectious Diseases and Clinical Microbiology Sanliurfa, Turkey. suda_tekinkoruk@yahoo.com
authors.forename: Suda
authors.initials: S
authors.lastname: Tekin-Koruk
authors.forename: Fazilet
authors.initials: F
authors.lastname: Duygu
authors.forename: Bensu
authors.initials: B
authors.lastname: Gursoy
authors.forename: Leman
authors.initials: L
authors.lastname: Karaagac
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bayraktar
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017347:Brucella melitensis / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D002443:Ceftriaxone / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D003863:Depression / Q000209:etiology; D004172:Diplopia / Q000209:etiology; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D012293:Rifampin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D002443:Ceftriaxone; D004318:Doxycycline; D012293:Rifampin