title: Isolation of pandamarilactonine-H from the roots of Pandanus amaryllifolius and synthesis of epi-pandamarilactonine-H.
abstract: A new alkaloid (1a), named pandamarilactonine-H, which possesses a methyl-2-(pyrrolidin-2-yl)acetate function, was isolated from the roots of Pandanus amaryllifolius. Eleven known alkaloids were also isolated. Unambiguous assignment of the structure of 1a, including the absolute configuration, was accomplished by spectroscopic analysis and total synthesis of its enantiomer.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Mario A
authors.initials: MA
authors.lastname: Tan
authors.forename: Mariko
authors.initials: M
authors.lastname: Kitajima
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kogure
authors.forename: Maribel G
authors.initials: MG
authors.lastname: Nonato
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takayama
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D031673:Pandanaceae / Q000737:chemistry*; D010679:Philippines; D018517:Plant Roots / Q000737:chemistry; D011759:Pyrrolidines / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D007783:Lactones; D011759:Pyrrolidines; C552232:pandamarilactonine-H