Metastatic breast cancer presenting as a primary hindgut neuroendocrine tumour.
The examination of limited, potentially non-representative fragments of tumour tissue from a core biopsy can be misleading and misdirect subsequent treatment, especially in cases where a primary tumour has not been identified. This case report is of a 65-year-old woman presenting with a destructive sacral mass, diagnosed on radiological imaging and core biopsy as a hindgut neuroendocrine tumour, which on histopathological review of the subsequently resected tumour was found instead to represent a metastasis from an occult hormone-positive breast cancer with neuroendocrine features.
Okines
Alicia F C
AF
Department of Medicine, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, U.K.
Hawkes
Eliza A
EA
Rao
Sheela
S
VAN As
Nicholas
N
Marsh
Henry
H
Riddell
Angela
A
Wilson
Philip O G
PO
Osin
Peter
P
Wotherspoon
Andrew C
AC
Wetherspoon
Andrew C
AC
D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009362:Neoplasm Metastasis; D018358:Neuroendocrine Tumors / Q000175:diagnosis* / Q000473:pathology