Preliminary characterization of Mus musculus-derived pathogenic strains of Leptospira borgpetersenii serogroup Ballum in a hamster model.
Human and animal leptospirosis caused by Leptospira spp. belonging to serogroup Ballum has increased worldwide in the past decade. We report the isolation and serologic and molecular characterization of four L. borgpetersenii serogroup Ballum isolates obtained from Mus musculus, and preliminary virulence studies. These isolates are useful for diagnosis of leptospirosis and for epidemiologic studies of its virulence and pathogenic mechanisms.
da Silva
Everton F
EF
Centro de Biotecnologia and Departamento de Microbiologia e Parasitologia, Universidade Federal de Pelotas Pelotas, Rio Grande do Sul, Brazil. efsilva@ufpel.edu.br
Félix
Samuel R
SR
Cerqueira
Gustavo M
GM
Fagundes
Michel Q
MQ
Neto
Amilton C P S
AC
Grassmann
André A
AA
Amaral
Marta G
MG
Gallina
Tiago
T
Dellagostin
Odir A
OA
D000818:Animals; D006224:Cricetinae; D004195:Disease Models, Animal; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D007919:Leptospira / Q000145:classification* / Q000472:pathogenicity*; D007922:Leptospirosis / Q000382:microbiology* / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D014774:Virulence