title: Spatio-temporal dynamics in fMRI recordings revealed with complex independent component analysis.
abstract: Independent component analysis (ICA) of functional magnetic resonance imaging (fMRI) data is commonly carried out under the assumption that each source may be represented as a spatially fixed pattern of activation, which leads to the instantaneous mixing model. To allow modeling patterns of spatio-temporal dynamics, in particular, the flow of oxygenated blood, we have developed a convolutive ICA approach: spatial complex ICA applied to frequency-domain fMRI data. In several frequency-bands, we identify components pertaining to activity in primary visual cortex (V1) and blood supply vessels. One such component, obtained in the 0.10 Hz band, is analyzed in detail and found to likely reflect flow of oxygenated blood in V1.
authors.affiliation: Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego, La Jolla, CA, USA.
authors.forename: Jörn
authors.initials: J
authors.lastname: Anemüller
authors.forename: Jeng-Ren
authors.initials: JR
authors.lastname: Duann
authors.forename: Terrence J
authors.initials: TJ
authors.lastname: Sejnowski
authors.forename: Scott
authors.initials: S
authors.lastname: Makeig