Cu(I)-catalyzed regioselective diamination of conjugated dienes via dual mechanistic pathways.
This paper describes the Cu(I)-catalyzed regioselective diamination of conjugated dienes using di-tert-butyldiaziridinone as nitrogen source. The internal diamination and terminal diamination likely proceed via two mechanistic pathways. Various dienes can be efficiently diaminated at the internal double bonds with high regio- and diasteroselectivity in good yield using inexpensive CuBr as catalyst.
Zhao
Baoguo
B
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
Peng
Xingao
X
Cui
Sunliang
S
Shi
Yian
Y
D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D000475:Alkenes; D003300:Copper