[Preparation study of total lactone of Ginkgo controlled release pellet].
OBJECTIVE
To study the preparation technique of total lactone of Ginkgo controlled release pellet.


METHODS
Aquacoat as controlled release material, DBS as plasticizer, HPMC as diffusion promoter, the best manufacture technique was got according to the factors affecting the release of the pellet.


RESULTS
The controlled release pellet had good release rate and achieved the aim of controlling release.


CONCLUSIONS
The technique could be used for industrialization production.
Zhang
Jian-Hong
JH
Guangdong Food and Drug Vocational College, Guangzhou 510520, China. zhangjh@gdyzy.edu.cn
D046935:Bilobalides / Q000008:administration & dosage / Q000737:chemistry* / Q000493:pharmacokinetics; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D016503:Drug Delivery Systems; D004355:Drug Stability; D020441:Ginkgo biloba / Q000737:chemistry*; D010316:Particle Size; D018515:Plant Leaves / Q000737:chemistry; D010968:Plasticizers; D013678:Technology, Pharmaceutical / Q000379:methods*
D046935:Bilobalides; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D010968:Plasticizers