title: [Chronic kidney disease: screening attitude and practice in the absence of randomized controlled trials].
abstract: Given the increasing prevalence of chronic kidney disease (CKD), early detection has been proposed. Some organizations recommend CKD screening. Yet, the efficacy of CKD screening is unknown given the absence of randomized controlled trial conducted so far. While CKD screening tests (e.g., glomerular filtration rate) are simple and inexpensive, CKD screening can only be justified if it reduces CKD-related mortality and/or CKD-related morbidity compared to no screening. In addition, CKD screening must provide more benefits than risks to the participants and must be cost-effective. Based on observational studies and cost-effectiveness models, CKD screening has to be proposed to high risk population (patients with hypertension and/or diabetes) but not to the general population.
authors.affiliation: Département de médecine interne, HUG, 1211 Genève 14. belen.ponte@hcuge.ch
authors.forename: Belén
authors.initials: B
authors.lastname: Ponte
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Martin
authors.forename: Antoinette
authors.initials: A
authors.lastname: Pechère
authors.forename: Michel
authors.initials: M
authors.lastname: Burnier
authors.forename: Idris
authors.initials: I
authors.lastname: Guessous
mesh_terms: D002908:Chronic Disease; D006801:Humans; D007674:Kidney Diseases / Q000145:classification / Q000175:diagnosis*; D008403:Mass Screening; D012307:Risk Factors