title: Are insulin resistance index, IGF-1 and metabolic syndrome components correlates with severe preeclampsia?
abstract: OBJECTIVE
  Analyse the relation between insulin resistance and severe preeclampsia (SPE).
  
  
  METHODS
  Case control study paired by body mass index and gestational age; including 16 patients with severe SPE and 16 normotensive controls. Insulin resistance was assessed through the HOMA-IR and QUICKI-IS indexes.
  
  
  RESULTS
  There was no significant difference between the groups regarding the HOMA-IR and QUICKI-IS indexes and HDL cholesterol. Triglyceride levels were higher and the IGF-1 was lower in the SPE group than in the control group.
  
  
  CONCLUSIONS
  There were no differences in the insulin resitance indexes between the group with SPE and normal controls.
authors.affiliation: Programa de Pós-Graduação em Medicina: Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, RS, Brazil. edimarleigv@terra.com.br
authors.forename: Edimárlei Gonsales
authors.initials: EG
authors.lastname: Valério
authors.forename: Ana Lúcia Letti
authors.initials: AL
authors.lastname: Müller
authors.forename: Sérgio Hofmeister
authors.initials: SH
authors.lastname: Martins-Costa
authors.forename: José Geraldo
authors.initials: JG
authors.lastname: Lopes Ramos
authors.forename: Gustavo
authors.initials: G
authors.lastname: Rodini
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D024821:Metabolic Syndrome / Q000378:metabolism* / Q000503:physiopathology; D011225:Pre-Eclampsia / Q000378:metabolism* / Q000503:physiopathology; D011247:Pregnancy; D012720:Severity of Illness Index
chemical_list: D001786:Blood Glucose; D007334:Insulin-Like Growth Factor I