Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis.
The crystal structure of human carbonic anhydrase II in the monoclinic P2(1) space group with a doubled a axis from that of the usually observed unit cell has recently been reported, with one of the two molecules in the asymmetric unit demonstrating rotational disorder [Robbins et al. (2010), Acta Cryst. D66, 628-634]. The structure has been redetermined, with the coordinates of both pseudo-symmetrically related molecules in the crystallographic asymmetric unit translated by x' = x +/- 1/4, and no rotational disorder is observed. This corresponds to a different choice of how the four molecules in the unit cell should be grouped into pairs that represent a single asymmetric unit.
Robbins
Arthur H
AH
Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA.
Domsic
John F
JF
Agbandje-McKenna
Mavis
M
McKenna
Robert
R
D024402:Carbonic Anhydrase II / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006801:Humans
D024402:Carbonic Anhydrase II