Asthma in pregnancy: pathophysiology, diagnosis and management.
Asthma is a common, potentially serious, even life-threatening, chronic medical condition seen amongst nearly all groups of patients, regardless of ethnicity and socioeconomic circumstances. This article addresses the group of pregnant women with symptomatic asthma as well as those whose asthma is asymptomatic as a result of good control. The incidence, the pathophysiologic changes of pregnancy, and the interplay between these changes and asthma are reviewed in this article. The classification of these patients and appropriate management strategies are discussed.
Hardy-Fairbanks
Abbey J
AJ
Department of Obstetrics and Gynecology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA. Abbey.J.Hardy-Fairbanks@hitchcock.org
Baker
Emily R
ER
D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D004205:Cromolyn Sodium / Q000008:administration & dosage; D003577:Cytochrome P-450 Enzyme System; D000072470:Cytochrome P450 Family 4; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D009316:National Institutes of Health (U.S.); D010353:Patient Education as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D012119:Respiration; D012720:Severity of Illness Index; D013806:Theophylline / Q000008:administration & dosage; D014481:United States
D000305:Adrenal Cortex Hormones; D058666:Adrenergic beta-2 Receptor Agonists; D018927:Anti-Asthmatic Agents; D003577:Cytochrome P-450 Enzyme System; D013806:Theophylline; C465348:Cyp4f1 protein, rat; D000072470:Cytochrome P450 Family 4; D004205:Cromolyn Sodium