title: RIG-I "sees" the 5'-triphosphate.
abstract: RIG-I protects host cells against various RNA viruses by sensing viral RNAs in the cytoplasm. Crystal structures of RIG-I C-terminal domain bound to 5'-triphosphate dsRNA unveils how RIG-I recognizes the 5'-triphosphate moiety, a hallmark of viral RNAs (Lu et al., 2010).
authors.affiliation: Weill Medical College of Cornell University, New York, NY 10021, USA.
authors.forename: Chao
authors.initials: C
authors.lastname: Zheng
authors.forename: Hao
authors.initials: H
authors.lastname: Wu