title: Ethical considerations in choosing a model for population-based cystic fibrosis carrier screening.
abstract: Cystic fibrosis (CF) carrier testing can be used to inform reproductive decision making, allowing carriers to avoid having a child with CF. A government-funded, population-based CF carrier screening program would allow greater equity of access to this test. The setting in which CF carrier screening is offered significantly affects the extent to which participants make well informed, voluntary decisions to accept or decline testing. Screening offered before pregnancy and in non-clinical environments better promotes participant autonomy than screening offered in the prenatal consultation.
authors.affiliation: Austin Health, Melbourne, VIC, Australia. lucy.modra@austin.org.au
authors.forename: Lucy J
authors.initials: LJ
authors.lastname: Modra
authors.forename: R John
authors.initials: RJ
authors.lastname: Massie
authors.forename: Martin B
authors.initials: MB
authors.lastname: Delatycki
mesh_terms: D002755:Choice Behavior; D003550:Cystic Fibrosis / Q000235:genetics* / Q000517:prevention & control; D004992:Ethics, Medical; D005260:Female; D006580:Genetic Carrier Screening / Q000379:methods*; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D008962:Models, Theoretical; D011247:Pregnancy; D011296:Prenatal Diagnosis