[Multiple myeloma--analysis of patients diagnosed in Internal Diseases and Nephrology Department and Dialysis Center St. Lukas Hospital in Tarnow in years 1999-2009].
We analyzed 25 patients with multiple myeloma. All the patients fullfilled diagnostic criteria of International Myeloma Working Group (2003): presence of monoclonical protein in serum or/ and in urine (IgG 64%), IgA -16%, free light chains - 16%, in one patient (4%) biclonal typ plasmocytoma was diagnosed), at least 10% plasmocytes in the bone marrow and at list one evidence of end-organ damage such as anemia (92%), bone lesions (65%), hypercalcemia (36%) and renal insufficiency (92%). Acute renal failure was diagnosed in 60% of patients and 32% with chronic renal failure. Only 2 patients had normal renal function. 36% of patients required hemodialysis. Our analysis showed that almost all patients were admitted to hospital at a very advanced stage of the disease and renal failure was dominant, mostly at advanced stadium.
Sydor
Antoni
A
Oddział Chorób Wewnetrznych i Nefrologii z Ośrodkiem Dializ Szpitala Wojewódzkiego im. Sw. Łukasza w Tarnowie. asydor@mp.pl
Rosa
Józef
J
D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000209:etiology; D001847:Bone Diseases / Q000209:etiology; D018450:Disease Progression; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis*; D006435:Renal Dialysis / Q000706:statistics & numerical data; D051437:Renal Insufficiency / Q000209:etiology / Q000628:therapy