Synthesis of anti-microtubule N-(2-Arylindol-7-yl)benzenesulfonamide derivatives and their antitumor mechanisms.
Chiou
Chun-Tang
CT
School of Pharmacy, National Taiwan University, Taipei 10051, Taiwan.
Chen
Grace Shiahuy
GS
Chen
Meng-Ling
ML
Li
Huoming
H
Shi
Lei
L
Huang
Xiang-Hong
XH
Dai
Wei-Ming
WM
Chern
Ji-Wang
JW
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D002455:Cell Division; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D016195:G2 Phase; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D008297:Male; D008870:Microtubules / Q000737:chemistry* / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000378:metabolism; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000633:toxicity; D050257:Tubulin Modulators / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D000096926:Benzenesulfonamides
D000970:Antineoplastic Agents; D007211:Indoles; D013449:Sulfonamides; D050257:Tubulin Modulators; D000096926:Benzenesulfonamides; C554617:N-(2-phenylindol-7-yl)-4-methoxybenzenesulfonamide