[A case of cardiac sarcoidosis occurring during combination therapy by IFN alpha and ribavirin for chronic hepatitis C].
A 72-year-old woman received combination therapy with peginterferon alpha and ribavirin for treatment of chronic hepatitis C. Approximately 40 weeks after starting treatment, she developed an eruption in the left inner canthus and sarcoidosis was diagnosed after biopsy of the eruption. Combination therapy was discontinued, and further detailed examinations revealed bilateral hilar lymphadenopathy, uveitis, and complete atrioventricular block. A permanent cardiac pacemaker was implanted, and her sarcoidosis improved upon administration of corticosteroids.
Iwashita
Masahide
M
Department of Internal Medicine, Nishimino Kosei Hospital. iwashita@nishimino.gfkosei.or.jp
Maeda
Teruo
T
Tagami
Atsushi
A
Watanabe
Naoki
N
Takada
Jun
J
Asano
Takahiko
T
Hatakeyama
Hiroo
H
Hayashi
Takao
T
Nishiwaki
Shinji
S
Saito
Koshiro
K
D000368:Aged; D000998:Antiviral Agents / Q000009:adverse effects*; D009202:Cardiomyopathies / Q000209:etiology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects*; D012254:Ribavirin / Q000009:adverse effects*; D012507:Sarcoidosis / Q000209:etiology*
D000998:Antiviral Agents; D016898:Interferon-alpha; D012254:Ribavirin