title: Cirrhotic cardiomyopathy.
abstract: Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic liver transplantation result from overt heart failure. In this review, we critically evaluate the existing literature on the pathophysiology and clinical implications of cirrhotic cardiomyopathy.
authors.affiliation: Department of Clinical Medicine, University Campus Bio-Medico, Via Alvaro del Portillo, Rome, Italy. e.zardi@unicampus.it
authors.forename: Enrico M
authors.initials: EM
authors.lastname: Zardi
authors.forename: Antonio
authors.initials: A
authors.lastname: Abbate
authors.forename: Domenico Maria
authors.initials: DM
authors.lastname: Zardi
authors.forename: Aldo
authors.initials: A
authors.lastname: Dobrina
authors.forename: Domenico
authors.initials: D
authors.lastname: Margiotta
authors.forename: Benjamin W
authors.initials: BW
authors.lastname: Van Tassell
authors.forename: Benjamin W
authors.initials: BW
authors.lastname: Van Tassel
authors.forename: Antonella
authors.initials: A
authors.lastname: Afeltra
authors.forename: Arun J
authors.initials: AJ
authors.lastname: Sanyal
mesh_terms: D009202:Cardiomyopathies / Q000209:etiology* / Q000503:physiopathology*; D005355:Fibrosis; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000503:physiopathology*; D009206:Myocardium / Q000473:pathology*