CdSe/ZnS quantum dots-G-quadruplex/hemin hybrids as optical DNA sensors and aptasensors.
The luminescence of CdSe/ZnS QDs is quenched via electron transfer by hemin/G-quadruplex associated with the particles. This phenomenon is implemented to develop DNA sensors or aptasensors by tailoring hairpin-functionalized QDs that generate the hemin/G-quadruplex quenchers upon sensing of the respective analytes.
Sharon
Etery
E
Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Freeman
Ronit
R
Willner
Itamar
I
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods; D019187:Cadmium Compounds / Q000737:chemistry; D004247:DNA / Q000032:analysis*; D021881:DNA, Catalytic / Q000737:chemistry; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods*; D054856:G-Quadruplexes; D006046:Gold / Q000737:chemistry; D006427:Hemin / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013440:Sulfides / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
D052157:Aptamers, Nucleotide; D019187:Cadmium Compounds; D021881:DNA, Catalytic; D018036:Selenium Compounds; D013440:Sulfides; D017967:Zinc Compounds; D006427:Hemin; D006046:Gold; D004247:DNA; C058667:cadmium selenide; C031238:zinc sulfide