Association of psychiatric disorders, asthma and lung function in early adulthood.
OBJECTIVE
To examine the association between psychiatric disorders, asthma, and lung function in young adults.


METHODS
Data were from the Mater-University of Queensland Study of Pregnancy (MUSP). The study was based on 2443 young adults (1193 male and 1250 female) for whom data were available on psychiatric disorders, asthma, and respiratory function. Life time and last 12 months' generalized anxiety, panic, posttraumatic stress disorder (PTSD), and depressive disorders were assessed using a computerised version of the Composite International Diagnostic Interview (CIDI-Auto). A Spirobank G spirometer system was used to measure forced vital capacity (FVC), forced expiratory volume in one second (FEV(1)), and forced expiratory flow between 25% and 75% of forced vital capacity (FEF(25-75%)).


RESULTS
Participants with mental health disorders were more likely to have experienced asthma before or to use asthma medication at 21 years. However, for both males and females, life time and last 12 months' experience of generalized anxiety, panic, PTSD, and depressive disorders were not statistically significantly associated with FVC, FEV(1), and FEF(25-75%), except a modest association with major depressive disorders for males.


CONCLUSIONS
There is an association between mental health and asthma, but the relationship between mental health and lung function appeared to be confounded by the respondent's gender. More narrowly based prospective studies are required to determine the causal pathway between mental disorders and asthma.
Hayatbakhsh
Mohammad R
MR
School of Population Health, The University of Queensland, Herston Road,Herston, Queensland 4006, Australia. m.hayatbakhsh@uq.edu.au
Najman
Jake M
JM
Clavarino
Alexandra
A
Bor
William
W
Williams
Gail M
GM
O'Callaghan
Michael J
MJ
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D005540:Forced Expiratory Flow Rates; D005541:Forced Expiratory Volume; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D001523:Mental Disorders / Q000150:complications*; D013313:Stress Disorders, Post-Traumatic / Q000150:complications; D014797:Vital Capacity; D055815:Young Adult