title: Human papillomavirus infection is principally found with cervical intra-epithelial neoplasia-III in Toluca, State of Mexico.
abstract: BACKGROUND
  To describe the prevalence of human papillomavirus infection (HPV) in cases of cervical intra-epithelial neoplasia (CIN), micro-invasive carcinoma and invasive carcinoma in Toluca, State of Mexico.
  
  
  METHODS
  Cross-sectional study analysing slides with the diagnosis of CIN I to invasive carcinoma for one year and reporting the presence of HPV; also identifying these cervical-uterine cancer stages noted during one semester in the registery of histopathological studies, at the Department of Pathology, General Regional Hospital 220, Instituto Mexicano del Seguro Social (IMSS).
  
  
  RESULTS
  In one year, from a total of 5755 studies, 731 (13%) were of cervical-uterine cancer, 112 (16%) of these were positive for some stage of cervical cancer and 46.43% had HPV infection. In one semester, 2918 histopathological studies were done, 341 (11.68%) of these were cervix uterine biopsies, colposcopies and hysterectomies. 62 women (18.18%) diagnosed with CIN II-III, carcinoma in situ (CIS), micro-invasive carcinoma or invasive carcinoma and finding HPV infection in 51.92% of total cases.
  
  
  CONCLUSIONS
  The prevalence of HPV was higher than that reported in developed world and CIN II-III are the most common stages in Toluca, State of Mexico.
authors.affiliation: Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex), Paseo Tollocan ESQ, Jesús Carranza, Col. La Moderna, CP. 50180, Toluca, State of Mexico, Mexico. mezh_74@yahoo.com
authors.forename: Hugo
authors.initials: H
authors.lastname: Mendieta-Zerón
authors.forename: Raúl
authors.initials: R
authors.lastname: de León-Escobedo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009367:Neoplasm Staging; D030361:Papillomavirus Infections / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology / Q000473:pathology / Q000821:virology*