title: [Diagnosis and management of scrotal Paget's disease: report of 23 cases].
abstract: OBJECTIVE
  To explore the clinical manifestation, management, recurrence factors and prognosis of scrotal Paget's disease.
  
  
  METHODS
  We retrospectively analyzed the clinical and pathological data of 23 cases of scrotal Paget's disease diagnosed and treated in our hospital from 1996 to 2008.
  
  
  RESULTS
  The disease was confined to one side of the scrotum in 15, and involved the whole scrotum and penis in 8 of the cases. Three patients showed enlarged inguinal lymph nodes in the same side, and 2 in both sides. All the cases were confirmed by biopsy and treated by surgery. Post-operative follow-up was conducted for 2-68 months, which revealed 5 cases of local recurrence and 1 case of death for systemic metastasis.
  
  
  CONCLUSIONS
  Biopsy is proved to be important for the early diagnosis of scrotal Paget's disease, and extended excision of local lesion is a preferred management.
authors.affiliation: Department of Urology, The First Hospital Affiliated to China Medical University, Shenyang, Liaoning 110001, China. quebaobao@yahoo.com.cn
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.forename: Zhen-hua
authors.initials: ZH
authors.lastname: Li
authors.forename: Chui-ze
authors.initials: CZ
authors.lastname: Kong
mesh_terms: D000368:Aged; D005834:Genital Neoplasms, Male / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012611:Scrotum / Q000473:pathology*