Oral ulcer associated with alendronate: a case report.
Irritation of the mucosa of the aerodigestive tract is a well-known adverse effect of alendronate, whereas oral ulceration has been reported in only 14 articles in both the English and non-English literature. All of these have been associated with misuse of the drug. We here present the first case of severe oral ulceration attributable to use of alendronate without inappropriate therapeutic administration of the medication.
Kharazmi
Mohammad
M
Department of Oral and Maxillofacial Surgery, Central Hospital, Västerås, Sweden.
Sjöqvist
Kerstin
K
Rizk
Milad
M
Warfvinge
Gunnar
G
D000369:Aged, 80 and over; D019386:Alendronate / Q000009:adverse effects*; D001284:Atrophy; D001706:Biopsy; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000139:chemically induced; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology; D019226:Oral Ulcer / Q000139:chemically induced* / Q000473:pathology; D013280:Stomatitis / Q000139:chemically induced / Q000473:pathology; D014060:Tongue Diseases / Q000139:chemically induced* / Q000473:pathology
D050071:Bone Density Conservation Agents; D019386:Alendronate