Squaramide-based reagent for selective chromogenic sensing of Cu(II) through a zwitterion radical.
A minimalist squaramide-based chemodosimeter for Cu(2+) is described. Upon selective chelation to 2, Cu(2+) induces the formation of a highly colored zwitterionic radical, which is kinetically stable for hours. The presence of a radical is confirmed by EPR and ESI-MS. It is then possible to use reagent 2 for visual and selective sensing of Cu(2+) at neutral pH.
Sanna
Elena
E
Departament de Química, Universitat de les Illes Balears, 07122 Palma de Mallorca, Spain.
Martínez
Luis
L
Rotger
Carmen
C
Blasco
Salvador
S
González
Jorge
J
García-España
Enrique
E
Costa
Antoni
A
D000577:Amides / Q000737:chemistry*; D002614:Chelating Agents / Q000737:chemistry*; D003300:Copper / Q000032:analysis / Q000737:chemistry*; D003503:Cyclobutanes / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D014867:Water / Q000737:chemistry
D000577:Amides; D002614:Chelating Agents; D003503:Cyclobutanes; D005609:Free Radicals; D014867:Water; D003300:Copper; C030042:squaric acid