Laparoscopic ovarian transposition before pelvic irradiation: a Saudi tertiary center experience.
OBJECTIVE
To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy.


METHODS
Cohort study.


METHODS
The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia.


METHODS
Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy.


METHODS
Laparoscopic ovarian transposition to paracolic gutters with uterine conservation.


METHODS
Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level.


RESULTS
Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up.


CONCLUSIONS
Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.
Al-Badawi
Ismail A
IA
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. i_albadawi@yahoo.com
Al-Aker
Murad
M
AlSubhi
Jamal
J
Salem
Hany
H
Abduljabbar
Alaa
A
Balaraj
Khalid
K
Munkarah
Adnan
A
D000328:Adult; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006779:Hospitals, Public; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008875:Middle Aged; D010053:Ovary / Q000528:radiation effects / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D017697:Premenopause; D011835:Radiation Protection / Q000379:methods; D018714:Radiotherapy, Adjuvant; D020127:Recovery of Function; D018570:Risk Assessment; D012529:Saudi Arabia; D016896:Treatment Outcome