title: Bone mineral density in young Indian adults with traumatic proximal femoral fractures. A case control study.
abstract: There is scarcity of data on osteoporosis in India for the age group of 20-40 years when peak bone mass is achieved. This study aimed to assess bone mineral density (BMD) in patients in this age group with traumatic proximal femoral fractures, and to compare it with age matched controls. Thirty patients aged 20 to 40 years with traumatic proximal femoral fractures and 30 healthy volunteers within the same age group were included in the study. Radiographs of the pelvis were taken to determine the Singh index, and DEXA scan of the unaffected hip was done to assess BMD. Fracture cases were compared with controls for significant difference in BMD. The male to female ratio of the study was 2:1. Based on Singh's index, 60% of fracture cases and 20% of controls were osteoporotic. T scores by DEXA revealed that 24 patients with fracture and 22 controls had osteopenia or osteoporosis. There was a significant difference in the Singh index between the two groups and no significant difference in BMD assessed by DEXA scan. No agreement was found between BMD determined by DEXA and Singh's index. The study points that our population fails to attain an adequate peak bone mass. It also questions the applicability of Western data to Indian population. The findings also indicate that Singh's Index cannot substitute DEXA for diagnosis of osteoporosis.
authors.affiliation: Department of Orthopaedics, University College of Medical Sciences and GTB Hospital, Delhi, India. diveshgulati@yahoo.co.in
authors.forename: Divesh
authors.initials: D
authors.lastname: Gulati
authors.forename: Sudhir
authors.initials: S
authors.lastname: Kumar
authors.forename: Anil
authors.initials: A
authors.lastname: Arora
authors.forename: Aditya Nath
authors.initials: AN
authors.lastname: Aggarwal
authors.forename: S K
authors.initials: SK
authors.lastname: Bhargava
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001851:Bone Diseases, Metabolic / Q000453:epidemiology; D016022:Case-Control Studies; D005260:Female; D005264:Femoral Fractures / Q000453:epidemiology* / Q000209:etiology; D006620:Hip Fractures / Q000453:epidemiology; D006801:Humans; D007194:India; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis / Q000453:epidemiology*; D055815:Young Adult