title: Association between lipids and fibrinogen levels and ischemic stroke in the population of the Polish children with arteriopathy and cardiac disorders.
abstract: BACKGROUND
  The ischemic stroke is a rare problem in childhood. Cardiac problems, arteriopathy, coaguopathies or dyslipidemia are traditional risk factors for stroke. The aim of the present study was to assess the relations between levels of lipids and fibrinogen and stroke among Polish children.
  
  
  METHODS
  We studied 75 patients (mean age: 8.24 +/- 5.56) and 71 healthy children (mean age: 10.32 +/- 5.7). The diagnosis of ischemic stroke was established with the WHO definition.
  
  
  RESULTS
  Serum triacylglycerols level and plasma fibrinogen level may be considered as risk factors for childhood stroke (p=0.004, OR=7.01 and p=0.024, OR=2.16, respectively). In the subgroup of stroke children with cardiac problems the triacylglycerols level is also the risk factor for stroke (p=0.006, OR=7.14).
  
  
  CONCLUSIONS
  Levels of triacylglycerols and fibrinogen again differentiated the subgroup of children with neurological deficits from controls. In conclusion, the levels of triacylglycerols and fibrinogen are important risk factors in the etiology of stroke.
authors.affiliation: Katedra i Klinika Pediatrii i Neurologii Wieku Rozwojowego Slaskiego Uniwersytetu Medycznego w Katowicach. ilonakopyta@autograf.pl
authors.forename: Ilona
authors.initials: I
authors.lastname: Kopyta
authors.forename: Beata
authors.initials: B
authors.lastname: Sarecka-Hujar
authors.forename: Ewa
authors.initials: E
authors.lastname: Emich-Widera
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Marszał
authors.forename: Iwona
authors.initials: I
authors.lastname: Zak
mesh_terms: D000293:Adolescent; D002648:Child; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006331:Heart Diseases / Q000453:epidemiology / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D016491:Peripheral Vascular Diseases / Q000453:epidemiology / Q000378:metabolism*; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides; D005340:Fibrinogen