[Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease].
Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease, which can lead to life-threatening ventricular arrhythmias in patients with a structurally normal heart. The age of onset is usually between two and 12 years and the initial symptom is frequently syncope or cardiac arrest. The arrhythmias are usually triggered by exercise or emotional affection. The diagnosis is often made using exercise electrocardiogram, which typically triggers arrhythmias. The treatment consists of beta blockers, frequently in combination with implantation of a cardioverter-defibrillator.
Holst
Anders Gaarsdal
AG
Københavns Universitet, Danmarks Nationale Grundforskningsfonds Center for Hjertearytmi, Rigshospitalet, Hjertecentret, Hjertemedicinsk Klinik B, Laboratorium for Molekylaer Kardiologi. anders@kanten.dk
Tfelt-Hansen
Jacob
J
Olesen
Morten S
MS
Theilade
Juliane
J
Winkel
Bo G
BG
Christensen
Alex H
AH
Bundgaard
Henning
H
Haunsø
Stig
S
Svendsen
Jesper Hastrup
JH
D002395:Catecholamines / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006323:Heart Arrest / Q000175:diagnosis; D006801:Humans; D009154:Mutation; D019837:Ryanodine Receptor Calcium Release Channel / Q000235:genetics; D013575:Syncope / Q000175:diagnosis; D017180:Tachycardia, Ventricular / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy
D002395:Catecholamines; D019837:Ryanodine Receptor Calcium Release Channel