Drug-induced liver disease.
More than 1000 drugs have been associated with hepatic injury, which can present in all forms of acute and chronic liver disease. The identification and prevention of drug-induced liver disease remain challenging tasks for health care professionals as reliable and practical assessment tools are not currently available to diagnose drug-induced liver disease. The management of drug-induced liver injury is generally supportive, and the recognition and avoidance of causative agents remain the most effective strategy for positive clinical outcomes.
Kim
Jiwon W
JW
Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, University of Southern California School of Pharmacy, USC University Hospital, 1500 San Pablo Street, Los Angeles, CA 90033, USA. jiwonkim@usc.edu
Hattori
Akiko
A
Phongsamran
Paula V
PV
D000208:Acute Disease; D056486:Chemical and Drug Induced Liver Injury / Q000145:classification / Q000453:epidemiology / Q000209:etiology / Q000451:nursing / Q000503:physiopathology*; D002779:Cholestasis / Q000139:chemically induced; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology; D019587:Dietary Supplements; D018450:Disease Progression; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology; D008111:Liver Function Tests; D012307:Risk Factors
D003577:Cytochrome P-450 Enzyme System