Penile intraepithelial neoplasia and other premalignant lesions of the penis.
Invasive penile cancer is an aggressive malignancy that often requires partial or complete penile amputation. Premalignant penile lesions, such as penile intraepithelial neoplasia, will have been present prior to the development of invasive disease in a substantial percentage of patients. Early detection and treatment of premalignant penile lesions may prevent malignant progression while avoiding penile amputation. This review focuses on premalignant penile lesions and the associations of these lesions with the development of invasive penile cancer.
Crispen
Paul L
PL
Division of Urology, Department of Surgery, University of Kentucky, Lexington, KY 40536, USA. crispen.paul@uky.edu
Mydlo
Jack H
JH
D002278:Carcinoma in Situ / Q000473:pathology* / Q000628:therapy; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000473:pathology; D008297:Male; D030361:Papillomavirus Infections / Q000473:pathology; D010412:Penile Neoplasms / Q000473:pathology* / Q000628:therapy; D011230:Precancerous Conditions / Q000473:pathology*