Undiagnosed collecting duct carcinoma presenting as meningeal carcinomatosis and multiple bone metastases.
A 54-year-old woman presented with blepharoptosis, numbness in the lower lip, dysgeusia and pain in the extremities and back. MRI showed marked meningeal thickening and multiple bone lesions accompanying a prominent enhancing effect. CT scan of the chest and abdomen appeared to be unremarkable for primary cancer. She died 3 months after the admission, and postmortem autopsy showed a mass of about 2.5 cm in diameter in the renal medulla. Histological examination including immunohistochemistry confirmed the presence of a collecting duct carcinoma (CDC). This case is of particular interest because it emphasizes the possible fulminate clinical course of a small CDC.
Ohnishi
Shunsuke
S
Department of Internal Medicine, Kushiro Rosai Hospital, Kushiro. shunpou@hotmail.com
Dazai
Masayoshi
M
Iwasaki
Yoshinori
Y
Tsuzaka
Kazufumi
K
Takahashi
Tatsuro
T
Miyagishima
Takuto
T
D001859:Bone Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D055756:Meningeal Carcinomatosis / Q000175:diagnosis*; D008875:Middle Aged