Different types of optic disc shape in patients with advanced open-angle glaucoma.
OBJECTIVE
To study the characteristics of patients with advanced open-angle glaucoma.


METHODS
A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE).


RESULTS
After checking the medical history of 750 glaucoma patients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001).


CONCLUSIONS
In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.
Nakazawa
Toru
T
Department of Ophthalmology, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan. ntoru@oph.med.tohoku.ac.jp
Fuse
Nobuo
N
Omodaka
Kazuko
K
Aizawa
Naoko
N
Kuwahara
Souichiro
S
Nishida
Kohji
K
D005260:Female; D005902:Glaucoma, Open-Angle / Q000145:classification* / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure; D057066:Low Tension Glaucoma / Q000145:classification / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000145:classification; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000145:classification* / Q000175:diagnosis; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D015354:Vision, Low / Q000145:classification; D014792:Visual Acuity