title: Metastatic breast cancer presenting as a primary hindgut neuroendocrine tumour.
abstract: The examination of limited, potentially non-representative fragments of tumour tissue from a core biopsy can be misleading and misdirect subsequent treatment, especially in cases where a primary tumour has not been identified. This case report is of a 65-year-old woman presenting with a destructive sacral mass, diagnosed on radiological imaging and core biopsy as a hindgut neuroendocrine tumour, which on histopathological review of the subsequently resected tumour was found instead to represent a metastasis from an occult hormone-positive breast cancer with neuroendocrine features.
authors.affiliation: Department of Medicine, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, U.K.
authors.forename: Alicia F C
authors.initials: AF
authors.lastname: Okines
authors.forename: Eliza A
authors.initials: EA
authors.lastname: Hawkes
authors.forename: Sheela
authors.initials: S
authors.lastname: Rao
authors.forename: Nicholas
authors.initials: N
authors.lastname: VAN As
authors.forename: Henry
authors.initials: H
authors.lastname: Marsh
authors.forename: Angela
authors.initials: A
authors.lastname: Riddell
authors.forename: Philip O G
authors.initials: PO
authors.lastname: Wilson
authors.forename: Peter
authors.initials: P
authors.lastname: Osin
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Wotherspoon
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Wetherspoon
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009362:Neoplasm Metastasis; D018358:Neuroendocrine Tumors / Q000175:diagnosis* / Q000473:pathology