title: Repair scaffolding reaches new heights at blocked replication forks.
abstract: In this issue of Molecular Cell, Ohouo et al. (2010) show that Mec1 (hATR) promotes the association of Slx4 and Rtt107 with Dpb11 (hTopBP1) in response to MMS-induced DNA alkylation, suggesting that Slx4 and Rtt107 might coordinate repair factors specifically at damaged replication forks.
authors.affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, 1450 3rd Street, San Francisco, CA 94158-9001, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Downey
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Edenberg
authors.forename: David P
authors.initials: DP
authors.lastname: Toczyski