Copper-catalyzed Ficini [2 + 2] cycloaddition of ynamides.
The Ficini [2 + 2] cycloaddition using N-sulfonyl-substituted ynamides is described, featuring the utility of CuCl(2) and AgSbF(6) as catalysts. This work represents the first successful example of ynamides participating in a thermal [2 + 2] cycloaddition with enones.
Li
Hongyan
H
Division of Pharmaceutical Sciences and Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53705, USA.
Hsung
Richard P
RP
DeKorver
Kyle A
KA
Wei
Yonggang
Y
D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D013450:Sulfones / Q000737:chemistry
D000577:Amides; D013450:Sulfones; D003300:Copper