title: Advances in diagnostic testing for gastroesophageal reflux disease.
abstract: Gastroesophageal reflux disease (GERD) contributes substantially to morbidity and to costs in the United States health care system. The burden of this disease has resulted in attempts at improving diagnosis and characterizing patients. Numerous research and technical advances have enhanced our understanding of both the utility and limitations of a variety of diagnostic modalities. The purpose of this review is to highlight recent advances in GERD diagnostic testing and to discuss their implications for use in clinical practice. Topics addressed include esophageal pH monitoring, impedance testing, symptom association analyses, narrow-band imaging, and histopathology.
authors.affiliation: Division of Gastroenterology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611-2951, United States.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Gawron
authors.forename: Ikuo
authors.initials: I
authors.lastname: Hirano
mesh_terms: D003938:Diagnostic Techniques, Digestive System; D017097:Electric Impedance; D016099:Endoscopy, Gastrointestinal; D050782:Esophageal pH Monitoring; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis