HDAC inhibitors repress the polycomb protein BMI1.
Grant
Steven
S
Virginia Commonwealth University Health Sciences Center, Richmond, VA, USA. stgrant@vcu.edu
D045744:Cell Line, Tumor; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D000071221:Enhancer of Zeste Homolog 2 Protein; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology*; D006801:Humans; D009687:Nuclear Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D063150:Polycomb Repressive Complex 1; D063151:Polycomb Repressive Complex 2; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D012097:Repressor Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D014157:Transcription Factors / Q000037:antagonists & inhibitors / Q000378:metabolism
C069077:BMI1 protein, human; D004268:DNA-Binding Proteins; D056572:Histone Deacetylase Inhibitors; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; C498409:EZH2 protein, human; D000071221:Enhancer of Zeste Homolog 2 Protein; D063151:Polycomb Repressive Complex 2; D063150:Polycomb Repressive Complex 1