title: Chronic haematogenous osteomyelitis in children: a retrospective review of 167 patients in Malawi.
abstract: We present a retrospective review of 167 patients aged 18 years and under who were treated for chronic haematogenous osteomyelitis at our elective orthopaedic hospital in Malawi over a period of four years. The median age at presentation was eight years (1 to 18). There were 239 hospital admissions for treatment during the period of the study. In 117 patients one admission was necessary, in 35 two, and in 15 more than two. A surgical strategy of infection control followed by reconstruction and stabilisation was employed, based on the Beit CURE radiological classification of chronic haematogenous osteomyelitis as a guide to treatment. At a minimum follow-up of one year after the end of the study none of the patients had returned to our hospital with recurrent infection. A total of 350 operations were performed on the 167 patients. This represented 6.7% of all children's operations performed in our hospital during this period. One operation only was required in 110 patients and none required more than three. Below-knee amputation was performed in two patients with chronic calcaneal osteomyelitis as the best surgical option for function. The most common organism cultured from operative specimens was Staphylococcus aureus, and the tibia was the bone most commonly affected. Polyostotic osteomyelitis occurred in four patients. We believe this is the largest reported series of patients treated for chronic haematogenous osteomyelitis.
authors.affiliation: Barking, Havering and Redbridge University Hospitals, NHS Trust, Rom Valley Way, Romford, Essex RM7 0AG, UK. veronabeckles@gmail.com
authors.forename: V L L
authors.initials: VL
authors.lastname: Beckles
authors.forename: H Wynn
authors.initials: HW
authors.lastname: Jones
authors.forename: W J
authors.initials: WJ
authors.lastname: Harrison
mesh_terms: D000293:Adolescent; D016025:Bone Transplantation / Q000379:methods; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005269:Femur / Q000601:surgery; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D006811:Humerus / Q000601:surgery; D007223:Infant; D008295:Malawi; D008297:Male; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000601:surgery; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery*