Ratios of nine risk factors in children with recurrent febrile seizures.
Febrile seizures are the most common convulsive disorder of childhood, with a recurrence probability of 33%. The aim of the study was to determine the risk factors for recurrence of febrile seizures in children. In this descriptive, cross-sectional study, nine risk factors of recurrence of febrile seizures were investigated in 259 children with febrile seizures: (1) sex; (2) domicile; (3) income level; (4) family history of febrile seizures; (5) family history of epilepsy; (6) level of fever; (7) duration of fever; (8) type of seizure, simple vs complex; and (9) age at seizure onset. The risk factors were compared for 119 children with isolated febrile seizures (45.9% of the total) and 140 children with two or more febrile seizure recurrences (54.1%). Among the patients with and without recurrent febrile seizures, 32% and 18% were domiciled in nonurban areas, respectively (P = 0.012). There was a family history of febrile seizures in 57% and 44% of cases with and without recurrent febrile seizures, respectively (P = 0.031). According to the logistic regression analysis, a family history of febrile seizures was a risk factor that affected recurrence (P = 0.018; odds ratio OR = 1.933; 95% confidence interval CI = 1.121-3.333). We also found that domicile (P = 0.001) and income (P = 0.013) were risk factors for recurrence. A family history of epilepsy was not a significant risk factor (P = 0.129; OR = 2.110; 95% CI = 0.804-5.539).
Tosun
Ayse
A
Department of Pediatrics, Adnan Menderes University Medical Faculty, Aydin, Turkey.
Koturoglu
Guldane
G
Serdaroglu
Gul
G
Polat
Muzaffer
M
Kurugol
Zafer
Z
Gokben
Sarenur
S
Tekgul
Hasan
H
D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004777:Environment; D005192:Family Health; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016017:Odds Ratio; D012008:Recurrence; D012307:Risk Factors; D003294:Seizures, Febrile / Q000453:epidemiology / Q000235:genetics / Q000503:physiopathology*; D012737:Sex Factors