title: A randomized trial on root caries prevention in elders.
abstract: Root caries is common in institutionalized elders, and effective prevention methods are needed. This clinical trial compared the effectiveness of four methods in preventing new root caries. From 21 residential homes, 306 generally healthy elders having at least 5 teeth with exposed sound root surfaces were randomly allocated into one of four groups: (1) individualized oral hygiene instruction (OHI); (2) OHI and applications of 1% chlorhexidine varnish every 3 months; (3) OHI and applications of 5% sodium fluoride varnish every 3 months; and (4) OHI and annual applications of 38% silver diamine fluoride (SDF) solution. Two-thirds (203/306) of the elders were followed for 3 years. Mean numbers of new root caries surfaces in the four groups were 2.5, 1.1, 0.9, and 0.7, respectively (ANOVA, p < 0.001). SDF solution, sodium fluoride varnish, and chlorhexidine varnish were more effective in preventing new root caries than giving OHI alone.
authors.affiliation: Australian Research Centre for Population Oral Health, School of Dentistry, The University of Adelaide, Australia.
authors.forename: H P
authors.initials: HP
authors.lastname: Tan
authors.forename: E C M
authors.initials: EC
authors.lastname: Lo
authors.forename: J E
authors.initials: JE
authors.lastname: Dyson
authors.forename: Y
authors.initials: Y
authors.lastname: Luo
authors.forename: E F
authors.initials: EF
authors.lastname: Corbet
mesh_terms: D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use; D004245:DMF Index; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007326:Institutionalization; D008297:Male; D009735:Nursing Homes; D009910:Oral Hygiene; D010353:Patient Education as Topic; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use; D012112:Residential Facilities; D017213:Root Caries / Q000517:prevention & control*; D012648:Self Care; D018030:Silver Compounds; D012969:Sodium Fluoride / Q000627:therapeutic use; D014099:Toothbrushing / Q000379:methods; D014100:Toothpastes / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D005460:Fluorides, Topical; D000644:Quaternary Ammonium Compounds; D018030:Silver Compounds; D014100:Toothpastes; D012969:Sodium Fluoride; C024633:silver diamine fluoride; D002710:Chlorhexidine