title: Assessment of the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule system in dogs.
abstract: OBJECTIVE
  To assess the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule (WMC) system in healthy dogs.
  
  
  METHODS
  31 healthy adult dogs that weighed between 19.6 and 81.2 kg.
  
  
  METHODS
  Food was withheld overnight. The following morning, a WMC was orally administered to each dog, and each dog was then fed a test meal that provided a fourth of the daily energy requirements. A vest was fitted on each dog to hold a receiver that collected and stored data from the WMC. Measurements were obtained with each dog in its home environment. Regression analysis was used to assess the relationship between body weight and gastrointestinal transit times.
  
  
  RESULTS
  Gastric emptying time (GET) ranged from 405 to 897 minutes, small bowel transit time (SBTT) ranged from 96 to 224 minutes, large bowel transit time (LBTT) ranged from 427 to 2,573 minutes, and total transit time (TTT) ranged from 1,294 to 3,443 minutes. There was no positive relationship between body weight and gastrointestinal transit times. A nonlinear inverse relationship between body weight and GET and between body weight and SBTT best fit the data. The LBTT could not be explained by this model and likely influenced the poor fit for the TTT.
  
  
  CONCLUSIONS
  A positive relationship did not exist between body weight and gastrointestinal transit times. Dogs with the lowest body weight of the cohort appeared to have longer gastric and small intestinal transit times than did large- and giant-breed dogs.
authors.affiliation: Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
authors.forename: Carol S
authors.initials: CS
authors.lastname: Boillat
authors.forename: Frédéric P
authors.initials: FP
authors.lastname: Gaschen
authors.forename: Giselle L
authors.initials: GL
authors.lastname: Hosgood
mesh_terms: D000818:Animals; D049628:Body Size; D001835:Body Weight / Q000502:physiology*; D053704:Capsule Endoscopy / Q000379:methods / Q000662:veterinary; D004285:Dogs; D005260:Female; D005746:Gastric Emptying / Q000502:physiology; D005769:Gastrointestinal Motility / Q000502:physiology*; D005772:Gastrointestinal Transit / Q000502:physiology*; D008297:Male; D016065:Myoelectric Complex, Migrating / Q000502:physiology; D012044:Regression Analysis; D013045:Species Specificity; D013997:Time Factors