Hemodynamic effects of lipid emulsion after local anesthetic intoxication may be due to a direct effect of fatty acids on myocardial voltage-dependent calcium channels.
Pennec
Jean-Pierre
JP
Guillouet
Maité
M
Rannou
Fabrice
F
Arvieux
Charles C
CC
Gueret
Gildas
G
D000779:Anesthetics, Local / Q000506:poisoning*; D000818:Animals; D015220:Calcium Channels / Q000187:drug effects* / Q000378:metabolism; D005217:Fat Emulsions, Intravenous / Q000494:pharmacology; D005227:Fatty Acids / Q000494:pharmacology*; D006801:Humans; D009206:Myocardium / Q000378:metabolism; D051381:Rats
D000779:Anesthetics, Local; D015220:Calcium Channels; D005217:Fat Emulsions, Intravenous; D005227:Fatty Acids