title: Patients' attitudes towards generic drug substitution in Japan.
abstract: OBJECTIVE
  The aim of this study was to evaluate the understanding and attitude of Japanese patients towards generic drug substitutions.
  
  
  METHODS
  The subjects were male and female patients, who purchased their prescription medications at a pharmacy. A questionnaire was created to assess their attitudes towards generic drugs.
  
  
  RESULTS
  Of 1215 respondents, 68.4% knew the term "generic drugs." The majority of them had the correct understanding only on the following two points: generic drugs are less expensive than the brand name drugs (86.0%) and generic drugs contain the same active ingredients as brand name drugs (71.1%). However, their understanding was poor in other aspects of generic substitution: the availability and accessibility of generic drugs, etc. Only the experience of a previous generic drug substitution was significantly associated with the increased willingness for generic substitution (OR=2.93, CI 1.93-4.44). The main reasons for accepting generic substitutions were recommendations by physicians (48.6%) and by pharmacists (33.1%).
  
  
  CONCLUSIONS
  The public awareness program on generic drugs should be expanded to include more detailed information so that patients obtain the correct understanding of generic substitution. It is critical that physicians and pharmacists have the proper understanding of generic drug substitution and provide the correct information to patients.
authors.affiliation: Department of Drug Information and Communication, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, 260-8675 Chiba, Japan. erikokob@p.chiba-u.ac.jp
authors.forename: Eriko
authors.initials: E
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Karigome
authors.forename: Tomoya
authors.initials: T
authors.lastname: Sakurada
authors.forename: Nobunori
authors.initials: N
authors.lastname: Satoh
authors.forename: Shiro
authors.initials: S
authors.lastname: Ueda
mesh_terms: D000328:Adult; D001290:Attitude; D016568:Drugs, Generic / Q000627:therapeutic use*; D005260:Female; D006306:Health Surveys; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D010361:Patients / Q000523:psychology*; D055815:Young Adult
chemical_list: D016568:Drugs, Generic