A new tandem mass spectrometer for photofragment spectroscopy of cold, gas-phase molecular ions.
We present here the design of a new tandem mass spectrometer that combines an electrospray ion source with a cryogenically cooled ion trap for spectroscopic studies of cold, gas-phase ions. The ability to generate large ions in the gas phase without fragmentation, cool them to approximately 10 K in an ion trap, and perform photofragment spectroscopy opens up new possibilities for spectroscopic characterization of large biomolecular ions. The incorporation of an ion funnel, together with a number of small enhancements, significantly improves the sensitivity, signal stability, and ease of use compared with the previous instrument built in our laboratory.
Svendsen
Annette
A
Laboratoire de Chimie Physique Moléculaire, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCPM, Station 6, CH-1015 Lausanne, Switzerland.
Lorenz
Ulrich J
UJ
Boyarkin
Oleg V
OV
Rizzo
Thomas R
TR
D003080:Cold Temperature; D004581:Electronics; D004867:Equipment Design; D005740:Gases / Q000737:chemistry*; D036103:Nanotechnology; D013057:Spectrum Analysis / Q000295:instrumentation*; D053719:Tandem Mass Spectrometry / Q000295:instrumentation*
D005740:Gases