Cyclic alkenyl boronic half acid synthesis and applications.
The synthesis of cyclic alkenyl boronic half acids from vinyl and propenyl boronic esters and homoallylic alcohols by ring-closing metathesis is reported. The method is compatible with both conventional and microwave heating and comparable yields are obtained under both conditions. The cyclic alkenyl boronic acids participate in Suzuki-Miyaura coupling reactions in good yields.
McNulty
LuAnne
L
Butler University, 4600 Sunset Avenue, Indianapolis, Indiana 46208, USA. lmcnulty@butler.edu
Kohlbacher
Kris
K
Borin
Katie
K
Dodd
Bryan
B
Bishop
Jeni
J
Fuller
Lindsey
L
Wright
Zach
Z
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry*; D001897:Boronic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D003500:Cyclization; D004952:Esters / Q000737:chemistry*; D008872:Microwaves; D015394:Molecular Structure; D013237:Stereoisomerism
D000438:Alcohols; D001897:Boronic Acids; D004952:Esters