title: Comparison of central retinal thickness in healthy children and adults measured with the Heidelberg Spectralis OCT and the zeiss Stratus OCT 3.
abstract: OBJECTIVE
  to compare retinal thickness measurements obtained by the Spectralis and Stratus OCT 3 in healthy children and adults.
  
  
  METHODS
  central volume scan (25-scan pattern) and macular thickness map protocols were performed subsequently using the Spectralis OCT and Stratus OCT 3 on a randomly selected eye of 34 healthy adults (18-50 years) and 20 children (6-17 years). Nine Early Treatment Diabetic Retinopathy Study (ETDRS) subfields were analyzed and compared between the children and adults.
  
  
  RESULTS
  All retinal thickness measurements obtained by the Spectralis OCT were greater than those measured with the Stratus OCT 3 (p < 0.01). In adults, the mean paired difference of measurements with both devices was 64.9 ± 13.2 microm (central minimum) and 75.8 ± 4.7 μm (central subfield). In children, the respective values were 56.6 ± 13.1 microm and 69.7 ± 9.1 microm, being significantly lower (p < 0.05).
  
  
  CONCLUSIONS
  in healthy eyes, measurements with the Stratus OCT 3 can be adjusted to measurements obtained using the Spectralis OCT by the values mentioned above, considering differences between children and adults.
authors.affiliation: Department of Ophthalmology, Justus Liebig University, Universitätsklinikum Giessen und Marburg GmbH, Giessen Campus, Giessen, Germany.
authors.forename: Yaroslava
authors.initials: Y
authors.lastname: Chopovska
authors.forename: Melanie
authors.initials: M
authors.lastname: Jaeger
authors.forename: Ronny
authors.initials: R
authors.lastname: Rambow
authors.forename: Birgit
authors.initials: B
authors.lastname: Lorenz
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D002648:Child; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012160:Retina / Q000033:anatomy & histology*; D017678:Sex Distribution; D041623:Tomography, Optical Coherence / Q000295:instrumentation*; D055815:Young Adult