title: Bromoderma in a patient with migrating partial seizures in infancy.
abstract: A 5-month-old boy with migrating partial seizures in infancy acquired bromoderma 4 weeks after initiating potassium bromide (KBr) therapy (60mg/kg/day). Erythematous pustules appeared on the forehead within a few days of attaching electroencephalography electrodes, and on the cheek at the site of nasogastric tube fixation. These later developed into vegetant plaques. Bromoderma aggravated at the site of skin biopsy that was performed 4 weeks after KBr termination. Bromoderma tuberosum should be recognized widely, considering the increasing use of KBr for treating intractable childhood epilepsy.
authors.affiliation: Department of Child Neurology, National Center Hospital (NCH), National Center of Neurology and Psychiatry (NCNP), 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo 187-8551, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Nabatame
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Saito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakuma
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Komaki
authors.forename: Eiji
authors.initials: E
authors.lastname: Nakagawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugai
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Kentaro
authors.initials: K
authors.lastname: Uchiyama
authors.forename: Maki
authors.initials: M
authors.lastname: Kosaka
mesh_terms: D001965:Bromides / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D003875:Drug Eruptions / Q000175:diagnosis / Q000473:pathology; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D017680:Potassium Compounds / Q000009:adverse effects*; D012640:Seizures / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D001965:Bromides; D017680:Potassium Compounds; C039004:potassium bromide