title: Dual-energy lung perfusion computed tomography: a novel pulmonary functional imaging method.
abstract: Dual-energy computed tomography (DECT) can be used for visualization of pulmonary microvascular contrast material distribution, representing regional perfusion. It is performed as DECT angiography and allows for the reconstruction of morphologic images as well as of "perfusion maps." The authors of previous studies have shown its potential to reliably depict perfusion defects, mainly in the context of pulmonary embolism. Also in the diagnostic work-up of other pulmonary diseases, there might be additional functional information provided by dual-energy acquisition techniques. This review focuses on the physical and technical background and the potential clinical value of pulmonary DECT. Technical improvements of a second-generation dual-source CT system are elucidated.
authors.affiliation: Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Munich, Germany. sven.thieme@med.uni-muenchen.de
authors.forename: Sven F
authors.initials: SF
authors.lastname: Thieme
authors.forename: Thorsten R C
authors.initials: TR
authors.lastname: Johnson
authors.forename: Maximilian F
authors.initials: MF
authors.lastname: Reiser
authors.forename: Konstantin
authors.initials: K
authors.lastname: Nikolaou
mesh_terms: D000792:Angiography; D003287:Contrast Media; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D011652:Pulmonary Circulation; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media