title: Ovarian interstitial cell tumor in a South American sea lion (Otaria flavescens).
abstract: A case of an ovarian tumor is reported in an 8-yr-old South American sea lion (Otaria flavescens) kept in a marine park in Malta (35.57 degrees N, 14.25 degrees E). The neoplasm was a solid mass of dense sheets and nests of round to polyhedral, irregularly shaped cells with abundant, finely vacuolated cytoplasm. The nuclei were uniformly small and round to oval. The supporting stroma contained thecal cells. The tumor cells were positive for positive inhibin and vimentin and focally positive for cytokeratin by immunohistochemistry. The neoplasm was diagnosed as an ovarian sex cord-stromal tumor, specifically an interstitial cell tumor.
authors.affiliation: Department of Veterinary Experimental Science, University of Padua, Italy. b.biancani@gmail.com
authors.forename: Barbara
authors.initials: B
authors.lastname: Biancani
authors.forename: Geraldine
authors.initials: G
authors.lastname: Lacave
authors.forename: Gian Enrico
authors.initials: GE
authors.lastname: Magi
authors.forename: Giacomo
authors.initials: G
authors.lastname: Rossi
mesh_terms: D000818:Animals; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D046070:Sea Lions; D017154:Stromal Cells / Q000473:pathology*; D013799:Theca Cells / Q000473:pathology*