title: Big pharma moves from 'blockbusters' to 'niche busters'.
authors.forename: Elie
authors.initials: E
authors.lastname: Dolgin
mesh_terms: D055808:Drug Discovery; D004345:Drug Industry / Q000458:organization & administration*; D005380:Financing, Government; D006801:Humans; D009965:Orphan Drug Production / Q000191:economics / Q000706:statistics & numerical data; D035583:Rare Diseases / Q000188:drug therapy / Q000191:economics; D012106:Research / Q000458:organization & administration; D014481:United States; D014486:United States Food and Drug Administration / Q000191:economics