Chemoselective and regiospecific Suzuki coupling on a multisubstituted sp(3)-carbon in 1,1-diborylalkanes at room temperature.
The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp(3)-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.
Endo
Kohei
K
Waseda Institute for Advanced Study, Shinjuku, Tokyo, 169-8050, Japan. kendo@aoni.waseda.jp
Ohkubo
Takahiro
T
Hirokami
Munenao
M
Shibata
Takanori
T