title: Preterm birth and adolescent bone mineral content.
abstract: The purpose of this study was to determine the influence of preterm low birth weight on bone mineral content in adolescence. In 2007 to 2008, data on adolescents were obtained for study, including 16 females and 25 males who were born preterm (≤37 weeks' gestation) between October 1, 1989, and December 31, 1995, with a birth weight of less than 1850 g. Preterm low-birth-weight individuals were age- and sex-matched to full-term (>37 weeks) normal-birth-weight (>2500 g) controls. Total body, hip, and spine bone mineral content (BMC) was assessed using dual energy X-ray absorptiometry. Male preterm individuals had less BMC at the proximal femur in adolescence compared with controls ( p < 0.05). However, once adjusted for age, maturity, height, weight, physical activity, and diet, there were no differences between groups ( p < 0.05) in any bone parameters. These findings suggest that preterm birth and low birth weight did not influence bone accrual in these individuals at adolescence.
authors.affiliation: College of Kinesiology, University of Saskatchewan, Saskatoon, Canada. marta.erlandson@usask.ca
authors.forename: Marta C
authors.initials: MC
authors.lastname: Erlandson
authors.forename: Lauren B
authors.initials: LB
authors.lastname: Sherar
authors.forename: Adam D G
authors.initials: AD
authors.lastname: Baxter-Jones
authors.forename: Stefan A
authors.initials: SA
authors.lastname: Jackowski
authors.forename: Heidi
authors.initials: H
authors.lastname: Ludwig-Auser
authors.forename: Chris
authors.initials: C
authors.lastname: Arnold
authors.forename: Koravangattu
authors.initials: K
authors.lastname: Sankaran
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D001823:Body Composition; D015519:Bone Density / Q000502:physiology; D001846:Bone Development / Q000502:physiology; D001842:Bone and Bones / Q000737:chemistry*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight / Q000502:physiology*; D007231:Infant, Newborn; D008297:Male; D008903:Minerals / Q000032:analysis*; D009043:Motor Activity / Q000502:physiology; D011247:Pregnancy; D047928:Premature Birth / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D008903:Minerals