Breast mass in a patient with ovarian cancer: a case report.
BACKGROUND
Less than 1% of malignant breast masses represent metastases from an extramammary source. Gynecologic tumors rarely metastasize to the breast. We report 2 patients who developed a breast mass following a known diagnosis of metastatic ovarian carcinoma or primary peritoneal carcinoma.


METHODS
A 28-year-old woman receiving therapy for recurrent ovarian cancer developed a breast mass with pleomorphic calcifications that was an ovarian cancer metastasis. A 61-year-old woman with primary peritoneal carcinomatosis developed a new primary breast tumor expressing CA 125 at the end of adjuvant therapy for peritoneal cancer.


CONCLUSIONS
Treatment and prognosis for metastatic and primary breast lesions are different, therefore accurate differentiation using radiographic and pathologic criteria is essential. We describe unique features of primary and metastatic breast lesions in patients with ovarian cancer.
Gayathri
Suresh
S
Department of Medicine, Indiana University Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, 535 Barnhill Drive, RT 473, Indianapolis, IN 46202, USA.
Badve
Sunil
S
Matei
Daniela
D
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000556:secondary; D018394:CA-125 Antigen / Q000097:blood; D002277:Carcinoma / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000628:therapy; D010534:Peritoneal Neoplasms / Q000473:pathology* / Q000628:therapy
D018394:CA-125 Antigen