Stereospecific and highly stereoselective cyclopropanation reactions promoted by samarium.
Samarium metal and samarium diiodide have become important tools as selective cyclopropanating agents in organic synthesis due to their high chemo- and stereoselectivity. Therefore, Sm and SmI(2) are the ideal reagents to prepare cyclopropane derivatives. This tutorial review highlights C-C multiple bond cyclopropanation processes promoted by samarium or samarium diiodide.
Concellón
José M
JM
Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, Julián Clavería, 8, 33071 Oviedo, Spain. hrsolla@uniovi.es
Rodríguez-Solla
Humberto
H
Concellón
Carmen
C
del Amo
Vicente
V
D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D012493:Samarium / Q000737:chemistry*; D013237:Stereoisomerism
D003521:Cyclopropanes; D007454:Iodides; D012493:Samarium; C409809:samarium diiodide