title: Development of the ATAQ-IPF: a tool to assess quality of life in IPF.
abstract: BACKGROUND
  There is no disease-specific instrument to assess health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).
  
  
  METHODS
  Patients' perspectives were collected to develop domains and items for an IPF-specific HRQL instrument. We used item variance and Rasch analysis to construct the ATAQ-IPF (A Tool to Assess Quality of life in IPF).
  
  
  RESULTS
  The ATAQ-IPF version 1 is composed of 74 items comprising 13 domains. All items fit the Rasch model. Domains and the total instrument possess acceptable psychometric characteristics for a multidimensional questionnaire. The pattern of correlations between ATAQ-IPF scores and physiologic variables known to be important in IPF, along with significant differences in ATAQ-IPF scores between subjects using versus those not using supplemental oxygen, support its validity.
  
  
  CONCLUSIONS
  Patient-centered and careful statistical methodologies were used to construct the ATAQ-IPF version 1, an IPF-specific HRQL instrument. Simple summation scoring is used to derive individual domain scores as well as a total score. Results support the validity of the ATAQ-IPF, and future studies will build on that validity.
authors.affiliation: Autoimmune Lung Center and Interstitial Lung Disease Program, National Jewish Health, 1400 Jackson Street, Denver, Colorado 80206, USA. swigrisj@njc.org
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Swigris
authors.forename: Sandra R
authors.initials: SR
authors.lastname: Wilson
authors.forename: Kathy E
authors.initials: KE
authors.lastname: Green
authors.forename: David B
authors.initials: DB
authors.lastname: Sprunger
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Brown
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Wamboldt
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000503:physiopathology / Q000523:psychology*; D008168:Lung; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D011795:Surveys and Questionnaires