Electrochemical impedance study of the interaction of metal ions with unlabeled PNA.
The interactions of the metal ions Mg(2+), Zn(2+), Ni(2+), and Co(2+) with thin films of peptide nucleic acids (PNAs) were studied by electrochemical impedance spectroscopy (EIS), and the results show that Zn(2+), Ni(2+) and Co(2+) interacted favorably with the PNA film involving the backbone and the nucleobases with the exception of Mg(2+) for which the interaction with the backbone appears to be dominant.
Gao
Lan
L
Department of Chemistry, Beijing Normal University, Beijing, 100875, China.
Li
Congjuan
C
Li
Xiaohong
X
Kraatz
Heinz-Bernhard
HB
D003035:Cobalt / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000379:methods*; D007477:Ions / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry*; D008567:Membranes, Artificial; D009532:Nickel / Q000737:chemistry*; D020135:Peptide Nucleic Acids / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
D007477:Ions; D008567:Membranes, Artificial; D020135:Peptide Nucleic Acids; D003035:Cobalt; D009532:Nickel; D008274:Magnesium; D015032:Zinc