[Antioxidant activity and spectroscopic behavior study with DNA of several Salen Mn(II), Eu(III) complexes].
Five kinds of Salen Mn(II) and two kinds of Eu(III) complexes were synthesized. Under the system of NBT/L-methionine, which creates and detects O2*-, the complexes of antioxidant activity were studied, and the conclusion revealed that all Mn(II) complexes have obvious antioxidant activity. The fluorescence study indicated that all the Salen metal complexes could bind with DNA, which shows their potential anticancer activity.
Zhou
Hua-Lei
HL
Department of Chemistry, University of Science and Technology Beijing, Beijing 100083, China. hlzhou05@yahoo.com.cn
Dong
Yi-Fan
YF
Yang
Yun-Xu
YX
Deng
Xiao-Rong
XR
Lu
Yi-Qiang
YQ
D000970:Antineoplastic Agents / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry*; D056831:Coordination Complexes; D004247:DNA / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D013057:Spectrum Analysis
D000970:Antineoplastic Agents; D000975:Antioxidants; D056831:Coordination Complexes; C542902:Mn-salen; D009942:Organometallic Compounds; D005063:Europium; D004247:DNA