Clinicopathological differences between right- and left-sided colonic tumors and impact upon survival.
OBJECTIVE
This study is to analyze the clinicopathological differences between right- and left-sided colonic tumors and to evaluate the impact upon the patient's survival.


METHODS
In a period of 5 years (2004-2009), 453 patients were diagnosed with colorectal cancer.


RESULTS
From a total of 453 patients diagnosed with colon cancer, 56.5% of them were men, while 43.5% of them were women. Right-sided colonic tumors were diagnosed in 54.53% of the patients compared to the 45.47% of patients with left-sided colonic tumors. The size of colonic tumors is statistically significant greater in right-sided colonic tumors compared to left ones (P < 0.001). Left-sided colon cancer patients identified to have a statistically significant better overall 5-year survival rate compared to right-sided ones (P < 0.001).


CONCLUSIONS
Based upon our results, there is a different biological profile between right- and left-sided colonic tumors.
Christodoulidis
G
G
General Surgery Department, University Hospital of Larissa, 41110 Mezourlo, Larissa, Greece. gregsurg@yahoo.gr
Spyridakis
M
M
Symeonidis
D
D
Kapatou
K
K
Manolakis
A
A
Tepetes
K
K
D000230:Adenocarcinoma / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology*; D000368:Aged; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis