The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506 reveals several gene clusters responsible for the biosynthesis of toxins and secondary metabolites.
We report a draft sequence of the genome of Oscillatoria sp. PCC 6506, a cyanobacterium that produces anatoxin-a and homoanatoxin-a, two neurotoxins, and cylindrospermopsin, a cytotoxin. Beside the clusters of genes responsible for the biosynthesis of these toxins, we have found other clusters of genes likely involved in the biosynthesis of not-yet-identified secondary metabolites.
Méjean
Annick
A
Laboratoire Charles Friedel, UMR CNRS 7223, ENSCP Chimie ParisTech, 11 Rue Pierre et Marie Curie, 75231 Paris Cedex 05, France. annick-mejean@enscp.fr
Mazmouz
Rabia
R
Mann
Stéphane
S
Calteau
Alexandra
A
Médigue
Claudine
C
Ploux
Olivier
O
D001427:Bacterial Toxins / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics* / Q000502:physiology; D054300:Oscillatoria / Q000235:genetics*
D001427:Bacterial Toxins