Schisanartane nortriterpenoids with diverse post-modifications from Schisandra propinqua.
Twenty-one highly oxygenated nortriterpenoids with a schisanartane skeleton were isolated from the stems of Schisandra propinqua var. propinqua. These nortriterpenoids featured a polycyclic framework composed of 7/8/5 consecutive carbocycles, which were organized by similar 5/5/7/5/7/5 rings A-F and varied oxygen-containing rings G and H. A biosynthetic classification of these compounds is proposed on the basis of their diverse post-modifications.
Lei
Chun
C
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Huang
Sheng-Xiong
SX
Xiao
Wei-Lie
WL
Li
Xiao-Nian
XN
Pu
Jian-Xin
JX
Sun
Han-Dong
HD
D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019073:HT29 Cells; D006801:Humans; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D032141:Schisandra / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D004365:Drugs, Chinese Herbal; D014315:Triterpenes; C512131:schisanartane; D010100:Oxygen