Synthesis of the 6-deoxytalose-containing tri- and hexasaccharides of the O-antigen polysaccharide from Mesorhizobium huakuii IFO15243T.
The synthesis of a trisaccharide and a hexasaccharide, the monomer and dimer of the repeating unit of O-antigen polysaccharide from Mesorhizobium huakuii IFO15243, has been accomplished through suitable protecting group manipulations and stereoselective glycosylation reactions starting from commercially available l-rhamnose. The target oligosaccharides in the form of their p-methoxyphenyl glycosides are suitable for further glycoconjugate formation via selective cleavage of this group.
Zong
Guanghui
G
Department of Applied Chemistry, China Agricultural University, Beijing 100 193, China.
Feng
Yichen
Y
Liang
Xiaomei
X
Chen
Liezhong
L
Zhang
Jianjun
J
Wang
Daoquan
D
D003837:Deoxy Sugars / Q000737:chemistry*; D006601:Hexoses / Q000737:chemistry*; D019081:O Antigens / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis*; D012230:Rhizobiaceae / Q000737:chemistry
D003837:Deoxy Sugars; D006601:Hexoses; D019081:O Antigens; D009844:Oligosaccharides; C011754:6-deoxytalose