title: [49 year old patient with staphylococcal sepsis caused by agranulocytosis after polychemotheraphy].
abstract: This study presents a case of adverse effects of chemotherapeutic agents: alkylating drug (cisplatyna) and taksoin (taxol) on a patient with metastatic cancer of unknown primary which was manifesting with Krukenberg tumor symptoms. The main disease symptoms were caused by bone marrow malignant infiltrations, and pancytopenia in peripheral blood, but mainly staphylococcal sepsis and hemorrhagic diathesis. In conclusion, the need to be cautious while making the decision to implement chemotherapy on patients with very advanced cancer in terms of prolonging their lives was pointed out.
authors.affiliation: Szpital Wojewódzki im. Sw. Łukasza, Tarnów, II Odział Chorób Wewnetrznych i Ostrych Zatruć.
authors.forename: Barbara
authors.initials: B
authors.lastname: Chudy
authors.forename: Stanisław
authors.initials: S
authors.lastname: Łata
mesh_terms: D000380:Agranulocytosis / Q000209:etiology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D019046:Bone Marrow Neoplasms / Q000556:secondary*; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007725:Krukenberg Tumor / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D017239:Paclitaxel / Q000008:administration & dosage; D018805:Sepsis / Q000175:diagnosis / Q000209:etiology*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology*
chemical_list: D017239:Paclitaxel; D002945:Cisplatin