Reversible splenium lesion of the corpus callosum in hemorrhagic fever with renal failure syndrome.
This is the first case of virus-associated encephalitis/encephalopathy in which the pathogen was Hantaan virus. A 53-yr-old man presented fever, renal failure and a hemorrhagic tendency and he was diagnosed with hemorrhagic fever with renal failure syndrome (HFRS). In the course of his illness, mild neurologic symptoms such as dizziness and confusion developed and magnetic resonance images revealed a reversible lesion in the splenium of the corpus callosum. This case suggests that HFRS patients with neurologic symptoms like dizziness and mental slowing should be considered to have structural brain lesions and to require brain imaging studies.
Baek
Shin-Hye
SH
Department of Neurology, Chungbuk National University School of Medicine, Cheongju, Korea.
Shin
Dong-Ick
DI
Lee
Hyung-Suk
HS
Lee
Sung-Hyun
SH
Kim
Hye-Young
HY
Shin
Kyeong Seob
KS
Lee
Seung Young
SY
Han
Ho-Seong
HS
Han
Hyun Jeong
HJ
Lee
Sang-Soo
SS
D000914:Antibodies, Viral / Q000097:blood; D003337:Corpus Callosum / Q000473:pathology*; D003937:Diagnosis, Differential; D018063:Hantaan virus / Q000276:immunology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D006435:Renal Dialysis
D000914:Antibodies, Viral