Long-term complications and survival of patients after orthotopic liver transplantation.
BACKGROUND
The survival rates among patients after orthotopic liver transplantation (OLT) has increased to 83% and 75% at 1 and 5 years, respectively. However, these patients are at increased risk of long-term complications.


OBJECTIVE
To identify long-term complications and survivals among patients after OLT.


METHODS
From September 1999 to July 2009 we evaluated long-term complications among 78 consecutive patients after OLT including 46 males.


RESULTS
Complications de novo after OLT were metabolic (n = 38; 67%), infections (n = 13; 23%), recurrent liver disease (n = 12; 21%), osteopenia/osteoporosis (n = 10; 18%), acute/chronic rejection (n = 8; 14%), renal failure (n = 2; 4%) and Kaposi's sarcoma (n = 1). Their overall survival at 118 months was 55%.


CONCLUSIONS
The most common long-term complications after OLT were metabolic, infections, and disease recurrence.
Muñoz
L E
LE
Liver Unit, Dr. José Eleuterio González University Hospital, UANL, Monterrey, NL, México. linda_uanl@hotmail.com
Nañez
H
H
Rositas
F
F
Pérez
E
E
Razo
S
S
Cordero
P
P
Torres
L
L
Zapata
H
H
Hernández
M A
MA
Escobedo
M M
MM
D001851:Bone Diseases, Metabolic / Q000453:epidemiology; D006528:Carcinoma, Hepatocellular / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology; D006526:Hepatitis C / Q000601:surgery; D006801:Humans; D007239:Infections / Q000453:epidemiology; D008107:Liver Diseases / Q000145:classification* / Q000453:epidemiology / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects* / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology; D011183:Postoperative Complications / Q000145:classification / Q000453:epidemiology*; D012008:Recurrence; D051437:Renal Insufficiency / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors