title: Oxidative cyclization of a phenolic Schiff base and synthesis of a cyclometalated ruthenium nitrosyl complex: photoinduced NO release by visible light.
abstract: The reactivity of sigma-arylruthenium cyclometallate [Ru(L(SB1))(PPh(3))(2)Cl] [1; L(SB1)H(2) = 4-methyl-2-(4-nitrobenzylideneamino)phenol] with nitric oxide (NO) gave rise to nitrosylation at the metal center, ring nitration, and oxidative cyclization, affording benzoxazole derivative formation. The molecular structure of the resultant nitrosyl complex, [Ru(L(PB1))(PPh(3))(2)(NO)Cl](ClO(4)) [2; L(PB1)H = 5-methyl-7-nitro-2-(4-nitrophenyl)benzoxazole] was determined, and a different sigma-arylruthenium cyclometallate was characterized in which the benzoxazole derivative was found to be coordinated to the metal center. The crystal structure and IR and NMR spectral data confirmed the formation of a diamagnetic {RuNO}(6) species with a S = 0 ground state and a {Ru(II)NO(+)}(6) description of the {RuNO}(6) moiety. Coordinated NO in the resultant complex 2 was photolabile under visible light and was transferred to reduced myoglobin.
authors.affiliation: Department of Chemistry, Indian Institute of Technology (IIT) Roorkee, Roorkee 247667, Uttarakhand, India. ghoshfcy@iitr.ernet.in
authors.forename: Kaushik
authors.initials: K
authors.lastname: Ghosh
authors.forename: Sushil
authors.initials: S
authors.lastname: Kumar
authors.forename: Rajan
authors.initials: R
authors.lastname: Kumar
authors.forename: Udai P
authors.initials: UP
authors.lastname: Singh
authors.forename: Nidhi
authors.initials: N
authors.lastname: Goel
mesh_terms: D003500:Cyclization; D008027:Light; D009569:Nitric Oxide / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D019800:Phenol / Q000737:chemistry*; D055668:Photochemical Processes; D012428:Ruthenium / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D012545:Schiff Bases; D009569:Nitric Oxide; D019800:Phenol; D012428:Ruthenium