title: Self-assembly of hybrid dendrons into doubly segregated supramolecular polyhedral columns and vesicles.
abstract: The synthesis and structural analysis of supramolecular dendrimers self-assembled from 3 libraries containing 20 first-generation hybrid dendrons are reported. Combinations of benzyl ether, naphthyl methyl ether, and biphenyl methyl ether repeat units with different alkyl carboxylates at the apex of the dendron decreased its molecular solid angle to values that led to the discovery of a new mechanism of self-assembly. This new self-assembly mechanism generated a diversity of unprecedented supramolecular assemblies, including hollow and nonhollow singly or doubly segregated supramolecular columns and vesicles exhibiting polyhedral shapes. The polyhedral shape of the self-organized supramolecular dendrimers was demonstrated to be an intrinsic characteristic of all the doubly segregated structures. The self-assembly mechanism elucidated here provides access to new strategies that will be used to fabricate complex supramolecular organizations.
authors.affiliation: Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Mihai
authors.initials: M
authors.lastname: Peterca
authors.forename: Mohammad R
authors.initials: MR
authors.lastname: Imam
authors.forename: Pawaret
authors.initials: P
authors.lastname: Leowanawat
authors.forename: Brad M
authors.initials: BM
authors.lastname: Rosen
authors.forename: Daniela A
authors.initials: DA
authors.lastname: Wilson
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Wilson
authors.forename: Xiangbing
authors.initials: X
authors.lastname: Zeng
authors.forename: Goran
authors.initials: G
authors.lastname: Ungar
authors.forename: Paul A
authors.initials: PA
authors.lastname: Heiney
authors.forename: Virgil
authors.initials: V
authors.lastname: Percec