The effect of vulvar lichen sclerosus on quality of life and sexual functioning.
Lichen sclerosus (LS) is a chronic skin disorder mostly seen on the female anogenital skin. The aim of this study was to evaluate the quality of life (QoL) and sexuality in female patients with LS and to compare their scores with healthy controls. In addition, we wanted to find factors associated with impaired sexual functioning in patients with LS. Members of the Dutch LS foundation and support group were asked to fill in three questionnaires: the Dermatology Quality of Life Index, Female Sexual Function Index (FSFI) and Female Sexual Distress Scale (FSDS). 215 of 368 patients returned their questionnaire (58.4%). Their scores were compared to a control group which consisted of 61 women of similar age (p = 0.472) without a skin disorder. Of all domains of QoL, LS interfered most with sexual functioning. Patients significantly scored lower on all subscales of the FSFI (desire (p = 0.016), arousal (p < 0.001), lubrication (p < 0.001), orgasm (p < 0.001), satisfaction (p < 0.001) and pain (p < 0.001), indicating worse sexual functioning. These problems with sexual functioning brought about significant sexual distress (p < 0.001). Patients who experienced more influence on their QoL had more sexual difficulties, leading to more sexual distress independent of their age.
Van de Nieuwenhof
Hedwig P
HP
Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, Netherlands. h.nieuwenhof@obgyn.umcn.nl
Meeuwis
Kim A P
KA
Nieboer
Theodoor E
TE
Vergeer
Marianne C M
MC
Massuger
Leon F A G
LF
De Hullu
Joanne A
JA
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000150:complications / Q000503:physiopathology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D011788:Quality of Life / Q000523:psychology*; D012107:Research Design; D012657:Self-Help Groups; D012725:Sexual Behavior / Q000523:psychology*; D012735:Sexual Dysfunction, Physiological / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology*; D011795:Surveys and Questionnaires; D007724:Vulvar Lichen Sclerosus / Q000150:complications* / Q000503:physiopathology / Q000523:psychology*