Angioplasty for the infusion of fasudil hydrochloride to treat cerebral symptomatic vasospasm.
The present report describes the successful treatment of cerebral symptomatic vasospasm (SVS) after subarachnoid hemorrhage (SAH) with super-selective intra-arterial infusion of fasudil hydrochloride (ERIL((R))). We treated seventeen vascular territories in 12 patients with selective intra-arterial infusion of fasudil hydrochloride (FSD). FSD was infused through a catheter (a microcatheter in nine patients) at a rate of 1.0 to 1.5 mg/minute (total dose=30 to 60mg/1 vessel) for each vascular territory. Nineteen vascular territories (100%) were angiographically dilated and seven patients (58%) showed early improvement in neurological function after the procedure.
Sashida
J
J
Department of Neurosurgery, Showa General Hospital; Tokyo, Japan.
Nagata
K
K
Kawamoto
S
S
Abe
T
T
Mukasa
A
A
Imaizumi
Y
Y