DNA translocation through graphene nanopores.
We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, we observe larger blocked currents than for traditional solid-state nanopores. However, ionic current noise levels are several orders of magnitude larger than those for silicon nitride nanopores. These fluctuations are reduced with the atomic-layer deposition of 5 nm of titanium dioxide over the device. Unlike traditional solid-state nanopore materials that are insulating, graphene is an excellent electrical conductor. Use of graphene as a membrane material opens the door to a new class of nanopore devices in which electronic sensing and control are performed directly at the pore.
Merchant
Christopher A
CA
Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Healy
Ken
K
Wanunu
Meni
M
Ray
Vishva
V
Peterman
Neil
N
Bartel
John
J
Fischbein
Michael D
MD
Venta
Kimberly
K
Luo
Zhengtang
Z
Johnson
A T Charlie
AT
Drndić
Marija
M
D001692:Biological Transport; D004247:DNA / Q000737:chemistry*; D008567:Membranes, Artificial; D049329:Nanostructures
D008567:Membranes, Artificial; D004247:DNA