title: Effect of ultrasound-guided aspiration of hydrosalpingeal fluid during oocyte retrieval on the outcomes of in vitro fertilisation-embryo transfer: a randomised controlled trial (NCT01040351).
abstract: OBJECTIVE
  To determine whether the ultrasound-guided aspiration of hydrosalpingeal fluid at the time of oocyte retrieval can improve the outcomes of in vitro fertilisation-embryo transfer (IVF-ET).
  
  
  METHODS
  One hundred and ten women with ultrasound-visible hydrosalpinges were randomised to two groups based on computer generated randomisation list. Fifty-four women underwent ultrasound-guided aspiration of hydrosalpingeal fluid prior to IVF-ET and 53 women underwent IVF-ET without any prior intervention.
  
  
  RESULTS
  Patients who underwent aspiration of hydrosalpinges demonstrated a significantly increased implantation, clinical pregnancy rates. Among the patients in the aspiration group, the implantation rate and pregnancy rates were higher in the subgroup of patients with no reaccumulation of hydrosalpingeal fluid within the first 2 weeks after aspiration compared to patients with reaccumulation of hydrosalpingeal fluid within the first 2 weeks after aspiration, but this difference failed to reach statistical significance. Furthermore, no pregnancies occurred in the four patients with uterine fluid collection detected during IVF-ET cycles.
  
  
  CONCLUSIONS
  The aspiration of hydrosalpingeal fluid at the time of oocyte retrieval is simple, safe and effective procedure for treatment of patients with ultrasound-visible hydrosalpinges particularly those without rapid reaccumulation of hydrosalpingeal fluid after aspiration or uterine fluid collection during the IVF-ET cycles.
authors.affiliation: Obstetrics and Gynaecology Department, Faculty of Medicine, Cairo University, Cairo, Egypt. umfrfouda@yahoo.com
authors.forename: Usama M
authors.initials: UM
authors.lastname: Fouda
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Sayed
mesh_terms: D000328:Adult; D001826:Body Fluids / Q000166:cytology*; D010064:Embryo Implantation; D004624:Embryo Transfer; D004716:Endometritis / Q000150:complications; D019160:Endosonography; D005187:Fallopian Tubes / Q000000981:diagnostic imaging / Q000276:immunology / Q000378:metabolism; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007246:Infertility / Q000150:complications / Q000628:therapy; D054315:Oocyte Retrieval / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D012488:Salpingitis / Q000150:complications / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000628:therapy*; D055502:Secondary Prevention; D013396:Suction / Q000009:adverse effects / Q000379:methods; D018084:Ultrasonography, Interventional / Q000009:adverse effects; D014599:Uterus / Q000276:immunology / Q000378:metabolism