title: [Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease].
abstract: Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease, which can lead to life-threatening ventricular arrhythmias in patients with a structurally normal heart. The age of onset is usually between two and 12 years and the initial symptom is frequently syncope or cardiac arrest. The arrhythmias are usually triggered by exercise or emotional affection. The diagnosis is often made using exercise electrocardiogram, which typically triggers arrhythmias. The treatment consists of beta blockers, frequently in combination with implantation of a cardioverter-defibrillator.
authors.affiliation: Københavns Universitet, Danmarks Nationale Grundforskningsfonds Center for Hjertearytmi, Rigshospitalet, Hjertecentret, Hjertemedicinsk Klinik B, Laboratorium for Molekylaer Kardiologi. anders@kanten.dk
authors.forename: Anders Gaarsdal
authors.initials: AG
authors.lastname: Holst
authors.forename: Jacob
authors.initials: J
authors.lastname: Tfelt-Hansen
authors.forename: Morten S
authors.initials: MS
authors.lastname: Olesen
authors.forename: Juliane
authors.initials: J
authors.lastname: Theilade
authors.forename: Bo G
authors.initials: BG
authors.lastname: Winkel
authors.forename: Alex H
authors.initials: AH
authors.lastname: Christensen
authors.forename: Henning
authors.initials: H
authors.lastname: Bundgaard
authors.forename: Stig
authors.initials: S
authors.lastname: Haunsø
authors.forename: Jesper Hastrup
authors.initials: JH
authors.lastname: Svendsen
mesh_terms: D002395:Catecholamines / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006323:Heart Arrest / Q000175:diagnosis; D006801:Humans; D009154:Mutation; D019837:Ryanodine Receptor Calcium Release Channel / Q000235:genetics; D013575:Syncope / Q000175:diagnosis; D017180:Tachycardia, Ventricular / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy
chemical_list: D002395:Catecholamines; D019837:Ryanodine Receptor Calcium Release Channel