title: Synthesis of gamma-halogenated ketones via the Ce(IV)-mediated oxidative coupling of cyclobutanols and inorganic halides.
abstract: A straightforward method for the synthesis of gamma-halo-substituted ketones formed via the CAN-initiated oxidative addition of halides to 1-substituted cyclobutanols has been developed. This method has short reaction times, and provides access to a range of bromo and iodo gamma-substituted ketones in good to excellent yields.
authors.affiliation: Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Casey
authors.forename: Cynthia A
authors.initials: CA
authors.lastname: Eakin
authors.forename: Robert A
authors.initials: RA
authors.lastname: Flowers