title: Shrink film patterning by craft cutter: complete plastic chips with high resolution/high-aspect ratio channel.
abstract: This paper presents a rapid, ultra-low-cost approach to fabricate microfluidic devices using a polyolefin shrink film and a digital craft cutter. The shrinking process (with a 95% reduction in area) results in relatively uniform and consistent microfluidic channels with smooth surfaces, vertical sidewalls, and high aspect ratio channels with lateral resolutions well beyond the tool used to cut them. The thermal bonding of the layers results in strongly bonded devices. Complex microfluidic designs are easily designed on the fly and protein assays are also readily integrated into the device. Full device characterization including channel consistency, optical properties, and bonding strength are assessed in this technical note.
authors.affiliation: Department of Biomedical Engineering, University of California, Irvine, USA.
authors.forename: Douglas
authors.initials: D
authors.lastname: Taylor
authors.forename: David
authors.initials: D
authors.lastname: Dyer
authors.forename: Valerie
authors.initials: V
authors.lastname: Lew
authors.forename: Michelle
authors.initials: M
authors.lastname: Khine
mesh_terms: D000818:Animals; D007118:Immunoassay; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D055616:Microtechnology / Q000379:methods*; D055096:Optical Devices; D010969:Plastics / Q000737:chemistry*; D019095:Point-of-Care Systems; D011090:Polyenes / Q000737:chemistry; D013499:Surface Properties
chemical_list: D010969:Plastics; D011090:Polyenes; C035051:PL 732