title: Preliminary characterization of Mus musculus-derived pathogenic strains of Leptospira borgpetersenii serogroup Ballum in a hamster model.
abstract: Human and animal leptospirosis caused by Leptospira spp. belonging to serogroup Ballum has increased worldwide in the past decade. We report the isolation and serologic and molecular characterization of four L. borgpetersenii serogroup Ballum isolates obtained from Mus musculus, and preliminary virulence studies. These isolates are useful for diagnosis of leptospirosis and for epidemiologic studies of its virulence and pathogenic mechanisms.
authors.affiliation: Centro de Biotecnologia and Departamento de Microbiologia e Parasitologia, Universidade Federal de Pelotas Pelotas, Rio Grande do Sul, Brazil. efsilva@ufpel.edu.br
authors.forename: Everton F
authors.initials: EF
authors.lastname: da Silva
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Félix
authors.forename: Gustavo M
authors.initials: GM
authors.lastname: Cerqueira
authors.forename: Michel Q
authors.initials: MQ
authors.lastname: Fagundes
authors.forename: Amilton C P S
authors.initials: AC
authors.lastname: Neto
authors.forename: André A
authors.initials: AA
authors.lastname: Grassmann
authors.forename: Marta G
authors.initials: MG
authors.lastname: Amaral
authors.forename: Tiago
authors.initials: T
authors.lastname: Gallina
authors.forename: Odir A
authors.initials: OA
authors.lastname: Dellagostin
mesh_terms: D000818:Animals; D006224:Cricetinae; D004195:Disease Models, Animal; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D007919:Leptospira / Q000145:classification* / Q000472:pathogenicity*; D007922:Leptospirosis / Q000382:microbiology* / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D014774:Virulence