title: The characterisation of mammalian tissue with 2D relaxation methods.
abstract: The potential of two-dimensional (2D) relaxometry for characterising mammalian tissue is explored on samples of liver, kidney (cortex, medulla and ureter) as well as cartilage. Significant differences are found between the T(1)-T(2) spectra of healthy and diseased human cartilage which suggests that 2D relaxometry could have potential use in clinical diagnosis. The effect of reducing the recovery delay on the T(1)-T(2) spectrum is explored to try to identify the optimum balance between speed and accuracy.
authors.affiliation: Institute of Food Research, Norwich Research Park, Colney, Norwich, UK.
authors.forename: Joshua
authors.initials: J
authors.lastname: Warner
authors.forename: Simon
authors.initials: S
authors.lastname: Donell
authors.forename: Kevin
authors.initials: K
authors.lastname: Wright
authors.forename: Luca
authors.initials: L
authors.lastname: Venturi
authors.forename: Brian
authors.initials: B
authors.lastname: Hills
mesh_terms: D000465:Algorithms; D000818:Animals; D001704:Biopolymers / Q000032:analysis* / Q000737:chemistry*; D002417:Cattle; D008099:Liver / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D001704:Biopolymers