title: Age-related changes in the localization of DNA methyltransferases during meiotic maturation in mouse oocytes.
abstract: The effects of maternal aging on the localization of DNA methyltransferases were evaluated during mouse oocyte maturation using fluorescence staining. And we conclude that maternal aging affects the cytoplasmic-to-nuclear trafficking of DNA methyltransferases in mouse oocytes during the time from germinal vesicle breakdown to metaphase I.
authors.affiliation: Department of Histology and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People's Republic of China.
authors.forename: Lu
authors.initials: L
authors.lastname: Zhang
authors.forename: Dan-Yu
authors.initials: DY
authors.lastname: Lu
authors.forename: Wan-Yun
authors.initials: WY
authors.lastname: Ma
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000378:metabolism*; D005260:Female; D006801:Humans; D008540:Meiosis / Q000502:physiology*; D051379:Mice; D009865:Oocytes / Q000737:chemistry / Q000201:enzymology* / Q000254:growth & development*; D009866:Oogenesis / Q000502:physiology*
chemical_list: D004248:DNA (Cytosine-5-)-Methyltransferases