title: [General principles for treatment of early rheumatoid arthritis].
abstract: The main goals of the treatment of a patient with RA are: to reduce pain, joint swelling and constitutional symptoms such as fatigue, to improve joint function, stop progression of bone-cartilage damage , prevent disabilities and reduce morbidity and mortality. In recent years, the therapeutic concept of early RA (first 12 months of symptoms) has undergone major changes. Three aspects in particular have become the basis of the new treatment paradigm: early diagnosis, immediate beginning of Disease Modifying Antirheumatic Drugs therapy (DMARD) and strict control of the inflammatory activity. In this article, the authors review the general principles of management of patients with early RA.
authors.affiliation: Serviço de Reumatologia, Faculdade de Medicina, Universidade de Brasília, Brasília, DF. licia@unb.br
authors.forename: Licia Maria Henrique da
authors.initials: LM
authors.lastname: Mota
authors.forename: Ieda Maria Magalhães
authors.initials: IM
authors.lastname: Laurindo
authors.forename: Leopoldo Luiz Dos
authors.initials: LL
authors.lastname: Santos Neto
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D042241:Early Diagnosis; D006801:Humans
chemical_list: D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents