title: Intraocular stability of an angle-supported phakic intraocular lens with changes in pupil diameter.
abstract: OBJECTIVE
  To use anterior segment optical coherence tomography (AS-OCT) to evaluate the stability of a recently released angle-supported phakic intraocular lens (pIOL) in the anterior segment with changes in pupil diameter.
  
  
  METHODS
  Keratoconus Unit, Vissum Corporation, Alicante, Spain.
  
  
  METHODS
  In this observational cross-sectional study of consecutive eyes with moderate to high myopia, an AcrySof Cachet pIOL was implanted with the aim of minimizing the refractive error. An analysis of the position and stability of the pIOL before and after pharmacologic pupil dilation was performed 3 months postoperatively using the Visante AS-OCT system. A measurement protocol that included several anatomic parameters was developed and applied; the parameter values before and after dilation were compared.
  
  
  RESULTS
  Twenty eyes of 20 patients ranging in age from 24 to 48 years old were evaluated. The anterior chamber depth increased significantly with pupil dilation (mean change 0.06 mm +/- 0.08 [SD]) (P<.01). A significant change was also observed in the distance between the center of the cornea at the endothelial plane and the anterior surface of the pIOL (mean change 0.03 +/- 0.05 mm) (P = .01). The distances between the peripheral edges of the pIOL and the corneal endothelium and the distance between the crystalline lens and the pIOL did not change significantly (P>or=.14).
  
  
  CONCLUSIONS
  The angle-supported pIOL showed excellent intraocular behavior after pupil dilation, with no shortening of the distance between the pIOL and corneal endothelium at the center or peripheral edges of the pIOL.
authors.affiliation: Division of Ophthalmology, Universidad Miguel Hernández, Keratoconus Unit, Vissum Corporation, Alicante, Spain. jlalio@vissum.com
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Alió
authors.forename: David P
authors.initials: DP
authors.lastname: Piñero
authors.forename: Esperanza
authors.initials: E
authors.lastname: Sala
authors.forename: Francisco
authors.initials: F
authors.lastname: Amparo
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000473:pathology* / Q000601:surgery*; D002452:Cell Count; D003430:Cross-Sectional Studies; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011680:Pupil / Q000502:physiology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult