title: When more is worse in clinical research and clinical practice.
authors.forename: Davide
authors.initials: D
authors.lastname: Tassinari
authors.forename: Paola
authors.initials: P
authors.lastname: Tombesi
authors.forename: Sergio
authors.initials: S
authors.lastname: Sartori
mesh_terms: D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D035843:Biomedical Research / Q000592:standards*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D000068818:Cetuximab; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D006801:Humans; D000077146:Irinotecan; D009362:Neoplasm Metastasis; D000077544:Panitumumab; D010818:Practice Patterns, Physicians' / Q000592:standards*; D011518:Proto-Oncogene Proteins / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras); D015203:Reproducibility of Results; D018631:ras Proteins / Q000235:genetics
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D000077544:Panitumumab; D000077146:Irinotecan; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins; D000068818:Cetuximab; D002166:Camptothecin