Sarcoidosis with cutaneous granulomatous vasculitis.
Ulceration of non-caseating granulomas is a rare cutaneous presentation of sarcoidosis. Granulomatous vasculitis is classically associated with Wegener's granulomatosis, lymphomatoid granulomatosis or Churg-Strauss syndrome. It is also commonly noted in pulmonary sarcoidosis, but has seldom been reported in cutaneous sarcoidosis, particularly the ulcerative variant. We present a rare case of sarcoidosis with multiple purpuric leg ulcers showing a granulomatous vasculitis histologically.
Wei
Chia-Hung
CH
Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Huang
Yu-Huei
YH
Shih
Yi-Chin
YC
Tseng
Fang-Wen
FW
Yang
Chi-Hsun
CH
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D056647:Systemic Vasculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013733:Testicular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
D011239:Prednisolone; D001379:Azathioprine