title: Oxaliplatin-induced acute thrombocytopenia.
abstract: We describe a patient who experienced immediate onset severe thrombocytopenia as part of a hypersensitivity reaction to oxaliplatin, following substantial relatively uncomplicated previous exposure to the drug. We review other reports of acute hematological toxicity from oxaliplatin. We draw attention to the important need for vigilance when patients develop unusual acute symptoms during or shortly after oxaliplatin infusion.
authors.affiliation: Bristol Haematology and Oncology Centre, Horfield Road, Bristol, BS2 8ED, UK.
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Mason
authors.forename: Gareth Jg
authors.initials: GJ
authors.lastname: Rees
mesh_terms: D000208:Acute Disease; D000368:Aged; D006801:Humans; D008297:Male; D009944:Organoplatinum Compounds / Q000009:adverse effects*; D000077150:Oxaliplatin; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis*
chemical_list: D009944:Organoplatinum Compounds; D000077150:Oxaliplatin