The CoFactor database: organic cofactors in enzyme catalysis.
BACKGROUND
Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database.


RESULTS
CoFactor provides a web interface to access hand-curated data extracted from the literature on organic enzyme cofactors in biocatalysis, as well as automatically collected information. CoFactor includes information on the conformational and solvent accessibility variation of the enzyme-bound cofactors, as well as mechanistic and structural information about the hosting enzymes.


BACKGROUND
The database is publicly available and can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/CoFactor.
Fischer
Julia D
JD
EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. julia.fischer@ebi.ac.uk
Holliday
Gemma L
GL
Thornton
Janet M
JM
D055162:Biocatalysis; D002384:Catalysis; D003067:Coenzymes / Q000737:chemistry* / Q000378:metabolism; D016208:Databases, Factual; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism; D020407:Internet; D011487:Protein Conformation
D003067:Coenzymes; D004798:Enzymes