Subunit exchange rates in Hepatitis B virus capsids are geometry- and temperature-dependent.
Native tandem mass spectrometry reveals marked differences in the rates at which the two polymorphic forms of the HBV capsid exchange dimeric subunits with the soluble pool.
Uetrecht
Charlotte
C
Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Watts
Norman R
NR
Stahl
Stephen J
SJ
Wingfield
Paul T
PT
Steven
Alasdair C
AC
Heck
Albert J R
AJ
D036022:Capsid Proteins / Q000737:chemistry*; D019281:Dimerization; D006515:Hepatitis B virus / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D013058:Mass Spectrometry; D021122:Protein Subunits / Q000737:chemistry; D013696:Temperature
D036022:Capsid Proteins; D021122:Protein Subunits