[Influence of native bacterial magnetic particles on mouse immune response].
OBJECTIVE
To study the influence of native bacterial magnetic particles on mouse immune response.


METHODS
Ovalbumin was used as an antigen, mixed with complete Freund's adjuvant, bacterial magnetic particles (BMP) and phosphate buffer solution, to immunize BALB/C mouse. After 14 days later, we detected the titers of the antiovalbumin (IgG) and subtype (IgG1, IgG2a) , the proliferation ability of T lymphocyte, and the expression of IL-2, IL4, IL-10 and IFN-gamma.


RESULTS
Compared to the negative control group, the BMP group had the similar level in the titer of specific antibody, the proliferation ability of T lymphocyte and the expression of cytokines (IL-2, IL-4, IL-10 and IFN-gamma).


CONCLUSIONS
Native BMPs has no significantly influence on mouse immune response.
Meng
Chen
C
State Key Laboratory for Agro-Biotechnology, Department of Microbiology and Immunology, College of Biological Science, China Agricultural University, Beijing 100193, China. mengchen2884@yahoo.com.cn
Tian
Jiesheng
J
Li
Ying
Y
Zheng
Shijun
S
D000818:Animals; D002478:Cells, Cultured; D016207:Cytokines / Q000276:immunology; D055944:Magnetosomes / Q000737:chemistry / Q000276:immunology*; D042201:Magnetospirillum / Q000737:chemistry / Q000276:immunology*; D008297:Male; D051379:Mice / Q000276:immunology*; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000276:immunology
D016207:Cytokines