title: Genotoxic analysis in aquatic environment under influence of cyanobacteria, metal and radioactivity.
abstract: The micronucleus (MN) and nuclear abnormality (NA) tests were employed to evaluate the genotoxic potential of the Lucrecia dam (RN, Brazil) located in a semi-arid region and influenced by crop irrigation and irregular rainfall. The analyses of these water samples demonstrated the presence of several cyanobacteria as well as metals and radioactivity. The Nile Tilapia (Oreochromis niloticus) was used for micronucleus and nuclear abnormality assays and analysis of metal concentrations in gills and liver samples. Genotoxic assays in source water fish showed a significant increase in the frequency of nuclear damage (MN and NA) in relation to the negative control group. In conclusion, the results obtained with water surface and biological samples from the Lucrecia dam suggest that this important water resource contains a number of chemical and microbiological pollutants with genotoxic potential and that these substances may be compromising the species inhabiting this ecosystem. Particular care must be taken to prevent further degradation of this water supply. Capsule: A battery of assay was successfully applied to assess the water quality of Lucrecia dam from a Northeastern region of Brazil.
authors.affiliation: Programa de Pós-graduação em Ciências da Saúde, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.
authors.forename: Alexandre Endres
authors.initials: AE
authors.lastname: Marcon
authors.forename: Douglisnilson de Morais
authors.initials: Dde M
authors.lastname: Ferreira
authors.forename: Maria de Fátima Vitória
authors.initials: Mde F
authors.lastname: de Moura
authors.forename: Thomas Ferreira da Costa
authors.initials: TF
authors.lastname: Campos
authors.forename: Viviane Souza
authors.initials: VS
authors.lastname: do Amaral
authors.forename: Lucymara Fassarella
authors.initials: LF
authors.lastname: Agnez-Lima
authors.forename: Sílvia Regina
authors.initials: SR
authors.lastname: Batistuzzo de Medeiros
mesh_terms: D000818:Animals; D023681:Cichlids / Q000502:physiology; D000458:Cyanobacteria / Q000145:classification / Q000254:growth & development* / Q000302:isolation & purification; D004784:Environmental Monitoring; D008670:Metals / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*; D015162:Micronucleus Tests; D009153:Mutagens / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*; D012621:Seasons; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*; D014875:Water Pollutants, Radioactive / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*
chemical_list: D008670:Metals; D009153:Mutagens; D014874:Water Pollutants, Chemical; D014875:Water Pollutants, Radioactive