The significance of non-T-cell pathways in graft rejection: implications for transplant tolerance.
Both innate and adaptive immune cells are actively involved in the initiation and destruction of allotransplants, and there is a true need now to look beyond T cells in the allograft response, examining various non-T-cell types in transplant models and how such cell types interact with T cells in determining the fate of an allograft. Studies in this area may lead to further improvement in transplant outcomes.
Li
Xian Chang
XC
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology; D006084:Graft Rejection / Q000276:immunology*; D006085:Graft Survival / Q000276:immunology; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D051379:Mice; D018448:Models, Immunological; D009000:Monocytes / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D023001:Transplantation Tolerance / Q000276:immunology*