title: Overall diet history and reversibility of the metabolic syndrome over 5 years: the Whitehall II prospective cohort study.
abstract: OBJECTIVE
  We examined the impact of adherence to the Alternative Healthy Eating Index (AHEI), a set of dietary guidelines targeting major chronic diseases, on metabolic syndrome (MetS) reversion in a middle-aged population.
  
  
  METHODS
  Analyses were carried out on the 339 participants (28% women, mean age 56.4 years) from the Whitehall II study with MetS as defined by the National Cholesterol Education Program Adult Treatment Panel III criteria. Reversion was defined as not having MetS after 5 years of follow-up (158 case subjects).
  
  
  RESULTS
  After controlling for potential confounders, adherence to AHEI was associated with MetS reversion (odds ratio 1.88 [95% CI 1.04-3.41]), predominantly in participants with central obesity and in those with high triglyceride.
  
  
  CONCLUSIONS
  Our findings support the benefit of adherence to AHEI dietary guidelines for individuals with MetS, especially those with central obesity or high triglyceride levels.
authors.affiliation: Department of Epidemiology and Public Health, University College London, London, UK. tasnime.akbaraly@inserm.fr
authors.forename: Tasnime N
authors.initials: TN
authors.lastname: Akbaraly
authors.forename: Archana
authors.initials: A
authors.lastname: Singh-Manoux
authors.forename: Adam G
authors.initials: AG
authors.lastname: Tabak
authors.forename: Markus
authors.initials: M
authors.lastname: Jokela
authors.forename: Marianna
authors.initials: M
authors.lastname: Virtanen
authors.forename: Jane E
authors.initials: JE
authors.lastname: Ferrie
authors.forename: Michael G
authors.initials: MG
authors.lastname: Marmot
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Shipley
authors.forename: Mika
authors.initials: M
authors.lastname: Kivimaki
mesh_terms: D004032:Diet; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D011446:Prospective Studies