title: Annular lipoatrophy of the ankles: case report and review of the literature.
abstract: Annular lipoatrophy of the ankles also termed "annular atrophic connective tissue panniculitis of the ankles,""annular atrophy of the ankles," and "atrophic annular panniculitis of the ankles," is an inflammatory panniculitis that results in lipoatrophy with a predilection for the ankles. The disorder is seen predominantly in female children and demonstrates a mixed lobular panniculitis. It is likely a disorder of autoimmune etiology, supported by the findings of concurrent autoimmune disorders in several patients. We report a case of a 6-year-old female with annular lipoatrophy of the ankles associated with Hashimoto thyroiditis and review the epidemiology and proposed pathogenesis of annular lipoatrophy of the ankles.
authors.affiliation: University of Cincinnati, Cincinnati, Ohio 45267-0592, USA.
authors.forename: Mary Jo
authors.initials: MJ
authors.lastname: Kerns
authors.forename: Susan
authors.initials: S
authors.lastname: Stinehelfer
authors.forename: Diya F
authors.initials: DF
authors.lastname: Mutasim
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Zalla
mesh_terms: D000842:Ankle; D001284:Atrophy; D002648:Child; D003240:Connective Tissue Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D015434:Panniculitis / Q000473:pathology*