Highly regio- and enantioselective catalytic asymmetric hydroboration of α-substituted styrenyl derivatives.
The catalytic asymmetric hydroboration of a variety of 1,1-disubstituted olefins has been achieved with excellent yields, perfect regioselectivity and in some cases, high levels of enantioselectivity using readily accessible iridium catalyst.
Mazet
Clément
C
University of Geneva, Organic Chemistry Department, Quai Ernest Ansermet 30, 1211-Geneva, Switzerland. clement.mazet@unige.ch
Gérard
David
D
D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*
D001896:Boron Compounds; D009942:Organometallic Compounds; D010080:Oxazoles; D013343:Styrenes; D007495:Iridium