Lactones and quinones from the tubers of Sinningia aggregata.
Three new aromatic epsilon-lactones, aggregatins A (1), B (2), and C (3), a new naphthoquinone derivative, aggregatin D (4), and three known anthraquinones, 2-methylanthraquinone, 7-methoxy-2-methylanthraquinone, and 7-hydroxy-2-methylanthraquinone, were isolated from the tubers of Sinningia aggregata (Gesneriaceae). Compounds 1 and 4 and the anthraquinones showed marginal antimicrobial activity.
Verdan
Maria Helena
MH
Departamento de Química, Universidade Federal do Paraná, CP 19081, 81530-900, Curitiba, PR, Brazil.
Barison
Andersson
A
de Sá
Eduardo Lemos
EL
Salvador
Marcos J
MJ
Poliquesi
Clarisse B
CB
Eberlin
Marcos N
MN
Stefanello
Maria Elida A
ME
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001938:Brazil; D004926:Escherichia coli / Q000187:drug effects; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009285:Naphthoquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects; D015003:Yeasts / Q000187:drug effects
D000880:Anthraquinones; D000890:Anti-Infective Agents; D007783:Lactones; D009285:Naphthoquinones; C552225:aggregatin A; C552226:aggregatin B; C552227:aggregatin C; C552224:aggregatin D; C073955:2-methylanthraquinone