Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa.
The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings.
Muyoyeta
Monde
M
Zambia AIDS Related Tuberculosis (ZAMBART), University of Zambia School of Medicine, Lusaka, Zambia. monde@zambart.org.zm
de Haas
Petra E W
PE
Mueller
Dirk H
DH
van Helden
Paul D
PD
Mwenge
Lawrence
L
Schaap
Ab
A
Kruger
Clarissa
C
Gey van Pittius
Nicolaas C
NC
Lawrence
Katherine
K
Beyers
Nulda
N
Godfrey-Faussett
Peter
P
Ayles
Helen
H
D001431:Bacteriological Techniques / Q000191:economics / Q000379:methods*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D013019:South Africa; D013997:Time Factors; D014376:Tuberculosis / Q000175:diagnosis*; D015024:Zambia