Screening for group B streptococcus: a private hospital's experience.
OBJECTIVE
To assess the effect of universal screening and administration of intrapartum antibiotic prophylaxis to prevent early-onset neonatal GBS sepsis at a private tertiary care hospital since issuance of the 2002 CDC guidelines for preventing perinatal GBS disease.


METHODS
Retrospective analysis of women delivering between January 1, 2003 and December 31, 2004 at a private tertiary care hospital in Houston, Texas. The percentage of women screened, GBS positive women receiving intrapartum antibiotic prophylaxis, and infants developing early-onset GBS sepsis were determined.


RESULTS
2,108 women delivered 2,135 infants with 1,874 (89%) screened for GBS. Of those screened, 1,322 (71%) tested negative and 552 (29%) tested positive for GBS. In this analysis of 2,135 infants, 3 (0.94 cases/1,000 live births) were diagnosed with invasive GBS sepsis.


CONCLUSIONS
High rates of screening of pregnant women for GBS colonization and use of intrapartum antibiotic prophylaxis for GBS carriers can be achieved in a private tertiary care hospital setting. "


CONCLUSIONS
High screening rates for group B streptococcus in a private tertiary care hospital reduce the incidence of maternal and early onset neonatal GBS infection."
Faro
Sebastian
S
The Woman's Hospital of Texas, Houston, TX 77054, USA.
Brehm
Brenda
B
Smith
Frances
F
Mouzoon
Melanie
M
Greisinger
Anthony
A
Wehmanen
Oscar
O
Turrentine
Mark A
MA
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis / Q000379:methods; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D016009:Chi-Square Distribution; D005260:Female; D016304:Hospitals, Private; D006801:Humans; D008403:Mass Screening; D010502:Perineum / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000517:prevention & control; D011295:Prenatal Care; D011296:Prenatal Diagnosis / Q000379:methods*; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology
D000900:Anti-Bacterial Agents