title: Oral ulcer associated with alendronate: a case report.
abstract: Irritation of the mucosa of the aerodigestive tract is a well-known adverse effect of alendronate, whereas oral ulceration has been reported in only 14 articles in both the English and non-English literature. All of these have been associated with misuse of the drug. We here present the first case of severe oral ulceration attributable to use of alendronate without inappropriate therapeutic administration of the medication.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Central Hospital, Västerås, Sweden.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kharazmi
authors.forename: Kerstin
authors.initials: K
authors.lastname: Sjöqvist
authors.forename: Milad
authors.initials: M
authors.lastname: Rizk
authors.forename: Gunnar
authors.initials: G
authors.lastname: Warfvinge
mesh_terms: D000369:Aged, 80 and over; D019386:Alendronate / Q000009:adverse effects*; D001284:Atrophy; D001706:Biopsy; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000139:chemically induced; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology; D019226:Oral Ulcer / Q000139:chemically induced* / Q000473:pathology; D013280:Stomatitis / Q000139:chemically induced / Q000473:pathology; D014060:Tongue Diseases / Q000139:chemically induced* / Q000473:pathology
chemical_list: D050071:Bone Density Conservation Agents; D019386:Alendronate