title: [Thrombotic complications of central venous catheters in hematooncological patients].
abstract: Central venous catheters (CVC) are frequently used in patients with a hematological disorders in order to administer drugs, stem cell infusions, blood products, parenteral alimentation as well as for blood sampling. There are known mechanical, infectious and thrombotic complications of central venous catheters in hematological patients. Infectious and thrombotic complications have been considered as separate entities so far, but there are theory and accumulating evidence that they are interrelated. Since data on central venous catheters-related thrombosis in hematological patients have been obtained mainly from retrospective studies of small size, prospective randomized studies are warranted. In this review we present current opinions about epidemiology, pathogenesis, diagnosis of CVC-related thrombosis and also its correlations with infectious CVC-related complications.
authors.affiliation: Katedra i Klinika Chorób Rozrostowych, Układu Krwiotwórczego w Poznaniu. mjoks@tlen.pl
authors.forename: Monika
authors.initials: M
authors.lastname: Joks
authors.forename: Renata
authors.initials: R
authors.lastname: Kroll
authors.forename: Mieczysław
authors.initials: M
authors.lastname: Komarnicki
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000706:statistics & numerical data; D015984:Causality; D015897:Comorbidity; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy*; D006801:Humans; D011292:Premedication; D015995:Prevalence; D012307:Risk Factors; D056824:Upper Extremity Deep Vein Thrombosis / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D014859:Warfarin