[Studies on the chemical constituents of Ligularia macrophylla].
OBJECTIVE
To study the chemical constituents of Ligularia macrophylla.


METHODS
Isolation and purification were carried out on repeated silica gel column chromatography. The structures of the compounds were identified by physico-chemical properties and spectral analyses.


RESULTS
Eight compounds were isolated and identified as kaempferol (1), 2,4'-dihydroxy-5-methoxychalcone (2), 5-hydroxy-3,4', 7-trimethoxyflavone (3), isobutyl ester terephthalic acid (4), 4-hydroxybenzaldehyde (5), mono (2-ethylhexyl) terephthalate (6), lupeol (7), beta-sitosterol (8).


CONCLUSIONS
Compounds 1 - 7 are isolated from this plant for the first time.
Tian
Qian-Qian
QQ
College of Pharmacy, Shihezi University, Shihezi 832002, China.
Wang
Guo-Yin
GY
Wen
Zhi-Ping
ZP
Cheng
Yu-Huai
YH
Wang
Qi
Q
D019659:Asteraceae / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry / Q000302:isolation & purification; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D044949:Kaempferols / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D000094042:Lupanes
D001547:Benzaldehydes; D001578:Benzopyrans; D005419:Flavonoids; D044949:Kaempferols; D053978:Pentacyclic Triterpenes; C006552:kaempferol; C011483:4-hydroxybenzaldehyde; C010480:lupeol; D000094042:Lupanes