title: Toxic hepatitis induced by show-wu-pian, a Chinese herbal preparation.
abstract: Herbal preparations are widely available and often regarded by the public as harmless remedies for a variety of medical ailments. However, some of these products or their metabolites can cause adverse effects such as liver damage. In this case report a 53-year-old female taking shou-wu-pian for 8 months presented with acute hepatitis. Histopathological assessment of liver tissue obtained by biopsy was consistent with a toxic reaction. Clinical and biochemical resolution was brought about following cessation of the drug. It is important for clinicians to consider Chinese herbal preparations as a potential cause of abnormal liver function test results.
authors.affiliation: Aoyama Hospital, Tokyo Women's Medical University.
authors.forename: Maiko
authors.initials: M
authors.lastname: Furukawa
authors.forename: Saeko
authors.initials: S
authors.lastname: Kasajima
authors.forename: Yuri
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Meiko
authors.initials: M
authors.lastname: Shouzushima
authors.forename: Naho
authors.initials: N
authors.lastname: Nagatani
authors.forename: Akira
authors.initials: A
authors.lastname: Takinishi
authors.forename: Ayumi
authors.initials: A
authors.lastname: Taguchi
authors.forename: Mikiko
authors.initials: M
authors.lastname: Fujita
authors.forename: Akiko
authors.initials: A
authors.lastname: Niimi
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Misaka
authors.forename: Hikaru
authors.initials: H
authors.lastname: Nagahara
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008111:Liver Function Tests / Q000639:trends; D008875:Middle Aged; D018517:Plant Roots; D028502:Polygonum
chemical_list: D004365:Drugs, Chinese Herbal