Therapeutic drug monitoring of mycophenolic acid: a potential treatment for lupus nephritis.
Mycophenolate mofetil, an immunosuppressant approved for the prevention of transplant rejection, has been used in patients with lupus nephritis. Lertdumrongluk et al. suggest that mycophenolic acid exposure may predict therapeutic responses in severe lupus nephritis, and their initial results confirm that hypothesis. However, it seems that enteric-coated mycophenolate sodium should not be administered to patients provided with therapeutic drug monitoring.
Pawinski
Tomasz
T
Medical University of Warsaw, Department of Drug Chemistry, Warsaw, Poland. tompaw@farm.amwaw.edu.pl
D000075202:Contraindications; D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D008181:Lupus Nephritis / Q000188:drug therapy*; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use*; D011379:Prognosis; D013608:Tablets, Enteric-Coated
D013608:Tablets, Enteric-Coated; D009173:Mycophenolic Acid