title: DNA repair has a new FAN1 club.
abstract: In recent issues of Molecular Cell, Cell, and Science, Smogorzewska et al. (2010), MacKay et al. (2010), Kratz et al. (2010), and Liu et al. (2010) identify FAN1 as a nuclease that is recruited to sites of interstrand crosslinks by ubiquitylated FANCD2, where it participates in DNA repair. The identification of FAN1 fills a missing link in interstrand crosslink DNA repair.
authors.affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada.
authors.forename: Lara
authors.initials: L
authors.lastname: O'Donnell
authors.forename: Daniel
authors.initials: D
authors.lastname: Durocher