title: The burden and cost of ambulatory cases of rotavirus gastroenteritis in central Israel.
abstract: BACKGROUND
  While the burden of rotavirus infection with regard to hospitalizations has been extensively investigated, there are sparse data on the cost and impact of this infection on the ambulatory part of the health system in Israel.
  
  
  OBJECTIVE
  To investigate the burden of rotavirus infection on the ambulatory system in Israel.
  
  
  METHODS
  Infants younger than 3 years examined for acute gastrointestinal symptoms in four pediatric clinics had their stool tested for rotavirus. The parents were contacted 7-10 days later and questioned about the symptoms of illness, medications given, use of diapers, consumption of formula, and any loss of parents' workdays.
  
  
  RESULTS
  Rotavirus was detected in 71 of the 145 stool samples tested (49%). A total of 54 parents responded to the telephonic survey. Patients' mean age was 15.4 months. Three patients were hospitalized due to the illness. The mean duration of fever was 1.7 days. Infants with rotavirus gastroenteritis had on average 2.25 days of vomiting and 7.5 days of diarrhea. The average number of workdays lost was 2.65 days per RVGE case. The cost of the average case of RVGE in Israel is 257 euros; 69.64% of this cost (179 euros) is due to parental work loss.
  
  
  CONCLUSIONS
  Our results indicate that the economic impact of the ambulatory cases in Israel is quite significant.
authors.affiliation: Pediatric Infectious Diseases Unit, Wolfson Medical Center, Holon, Israel.
authors.forename: Michal
authors.initials: M
authors.lastname: Stein
authors.forename: Hector
authors.initials: H
authors.lastname: Roisin
authors.forename: Binyamin
authors.initials: B
authors.lastname: Morag
authors.forename: Sigal
authors.initials: S
authors.lastname: Ringel
authors.forename: Diana
authors.initials: D
authors.lastname: Tasher
authors.forename: Maya
authors.initials: M
authors.lastname: Vohl
authors.forename: Avraham
authors.initials: A
authors.lastname: Mizrahi
authors.forename: Meir
authors.initials: M
authors.lastname: Raz
authors.forename: Eli
authors.initials: E
authors.lastname: Somekh
mesh_terms: D000041:Absenteeism; D000553:Ambulatory Care / Q000191:economics*; D002675:Child, Preschool; D017281:Cost of Illness; D041381:Diapers, Infant / Q000191:economics; D003968:Diarrhea, Infantile / Q000503:physiopathology; D016527:Drug Costs; D004636:Emergency Service, Hospital / Q000191:economics; D005243:Feces / Q000821:virology; D005334:Fever / Q000503:physiopathology; D005759:Gastroenteritis / Q000191:economics / Q000503:physiopathology / Q000821:virology*; D006760:Hospitalization / Q000191:economics; D006801:Humans; D007223:Infant; D007225:Infant Food; D007557:Israel; D009819:Office Visits / Q000191:economics; D011446:Prospective Studies; D012400:Rotavirus Infections / Q000191:economics* / Q000503:physiopathology; D013997:Time Factors; D019037:Urban Health Services / Q000191:economics; D014839:Vomiting / Q000503:physiopathology