title: Epidemiology of gastroduodenal erosions in the general population: endoscopic results of the systematic investigation of gastrointestinal diseases in China (SILC).
abstract: OBJECTIVE
  Population-based endoscopic studies of gastroduodenal erosions are limited in the world. This study describes features of gastroduodenal erosions in a representative sample of the population in Shanghai, China.
  
  
  METHODS
  A total of 3600 individuals (aged 18-80 years) were randomly selected from the Shanghai region and asked to undergo endoscopy and provide a blood sample to test for H. pylori infection. Participants completed a general information questionnaire, and a Chinese version of the Reflux Disease Questionnaire; 20% were also invited to complete the 36-item Short Form Health Survey and Epworth Sleepiness Scale. Associations between gastroduodenal erosions and other factors were analyzed using a multiple logistic regression model.
  
  
  RESULTS
  In total, 3153 individuals (87.6%) completed the survey and provided blood samples, 1030 (32.7%) agreed for endoscopy and 1022 participants were suitable for analysis. In all, 510 participants (49.9%) had gastroduodenal erosions (502 with gastric erosions; 26 with duodenal erosions). No significant association was found between H. pylori infection and gastroduodenal erosions. Increasing age, increasing BMI and current smoking were independent predictors for the presence of gastric erosions, but not of duodenal erosions. Duodenal erosions were more prevalent among men, which were not found in gastric erosions. The majority of individuals with gastroduodenal erosions were asymptomatic.
  
  
  CONCLUSIONS
  Gastroduodenal erosions are more common in China than in Europe, North America, and South America. No significant association was found between H. pylori infection and gastroduodenal erosions in China. The majority of individuals with gastroduodenal erosions were asymptomatic.
authors.affiliation: Department of Health Statistics, Second Military Medical University, and Department of Gastroenterology, Changhai Hospital, Shanghai, China.
authors.forename: Xiuqiang
authors.initials: X
authors.lastname: Ma
authors.forename: Yanfang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Yan
authors.forename: Zhaoshen
authors.initials: Z
authors.lastname: Li
authors.forename: Duowu
authors.initials: D
authors.lastname: Zou
authors.forename: Jia
authors.initials: J
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005767:Gastrointestinal Diseases / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology*; D016481:Helicobacter Infections / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors