title: A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells.
abstract: A new rhodamine-based chemosensor (L1) was synthesized, and it exhibits high sensitivity and selectivity for the copper cation over other commonly coexistent metal ions in aqueous solution. Upon the addition of Cu(2+), the spirolactam ring of L1 was opened and a 1 : 1 metal-ligand complex was formed. Fluorescent imaging of Cu(2+) in living cells is also successfully demonstrated.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China.
authors.forename: Liang
authors.initials: L
authors.lastname: Huang
authors.forename: Xiao
authors.initials: X
authors.lastname: Wang
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Xie
authors.forename: Pinxian
authors.initials: P
authors.lastname: Xi
authors.forename: Zhengpeng
authors.initials: Z
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.forename: Yongjie
authors.initials: Y
authors.lastname: Wu
authors.forename: Decheng
authors.initials: D
authors.lastname: Bai
authors.forename: Zhengzhi
authors.initials: Z
authors.lastname: Zeng
mesh_terms: D045744:Cell Line, Tumor; D003300:Copper / Q000737:chemistry / Q000378:metabolism; D005456:Fluorescent Dyes; D006801:Humans; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry* / Q000378:metabolism*; D012996:Solutions
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D012996:Solutions; D003300:Copper