title: DNA translocation through graphene nanopores.
abstract: We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, we observe larger blocked currents than for traditional solid-state nanopores. However, ionic current noise levels are several orders of magnitude larger than those for silicon nitride nanopores. These fluctuations are reduced with the atomic-layer deposition of 5 nm of titanium dioxide over the device. Unlike traditional solid-state nanopore materials that are insulating, graphene is an excellent electrical conductor. Use of graphene as a membrane material opens the door to a new class of nanopore devices in which electronic sensing and control are performed directly at the pore.
authors.affiliation: Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Merchant
authors.forename: Ken
authors.initials: K
authors.lastname: Healy
authors.forename: Meni
authors.initials: M
authors.lastname: Wanunu
authors.forename: Vishva
authors.initials: V
authors.lastname: Ray
authors.forename: Neil
authors.initials: N
authors.lastname: Peterman
authors.forename: John
authors.initials: J
authors.lastname: Bartel
authors.forename: Michael D
authors.initials: MD
authors.lastname: Fischbein
authors.forename: Kimberly
authors.initials: K
authors.lastname: Venta
authors.forename: Zhengtang
authors.initials: Z
authors.lastname: Luo
authors.forename: A T Charlie
authors.initials: AT
authors.lastname: Johnson
authors.forename: Marija
authors.initials: M
authors.lastname: Drndić
mesh_terms: D001692:Biological Transport; D004247:DNA / Q000737:chemistry*; D008567:Membranes, Artificial; D049329:Nanostructures
chemical_list: D008567:Membranes, Artificial; D004247:DNA