Ischemia-modified albumin and cardiovascular risk markers in polycystic ovary syndrome with or without insulin resistance.
The aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS.
Caglar
Gamze S
GS
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ufuk, Ankara, Turkey. gamzesinem@hotmail.com
Oztas
Efser
E
Karadag
Demet
D
Pabuccu
Recai
R
Demirtas
Selda
S
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology*; D016893:Carotid Stenosis / Q000097:blood / Q000453:epidemiology; D016022:Case-Control Studies; D005260:Female; D006710:Homocysteine / Q000097:blood; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D007511:Ischemia / Q000097:blood / Q000453:epidemiology*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000453:epidemiology*; D012307:Risk Factors; D012709:Serum Albumin / Q000378:metabolism*; D055815:Young Adult
D015415:Biomarkers; D012709:Serum Albumin; D006710:Homocysteine; D002097:C-Reactive Protein