The implementation of screening for prostate cancer.
The objective of this study was to determine whether screening for prostate cancer (PC) reduces PC mortality and, if so, whether the required criteria to be introduced as a population-based screening program are satisfied. A literature review was conducted through electronic scientific databases. The screening tests, that is, PSA and digital rectal examination, have limited sensitivity and specificity for detecting PC; screening produces a beneficial stage shift and reduces PC mortality. Nevertheless, PC screening causes a large increase in the cumulative incidence, and the understanding of the economic cost and quality-of-life parameters are limited. PC screening cannot be justified yet in the context of a public health policy.
van Leeuwen
P J
PJ
Department of Urology, Erasmus University Medical Centre, Rotterdam, The Netherlands. p.vanleeuwen@erasmusmc.nl
van Vugt
H A
HA
Bangma
C H
CH
D051517:Digital Rectal Examination; D006284:Health Plan Implementation; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000331:legislation & jurisprudence / Q000379:methods; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis*
D017430:Prostate-Specific Antigen