title: Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa.
abstract: The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings.
authors.affiliation: Zambia AIDS Related Tuberculosis (ZAMBART), University of Zambia School of Medicine, Lusaka, Zambia. monde@zambart.org.zm
authors.forename: Monde
authors.initials: M
authors.lastname: Muyoyeta
authors.forename: Petra E W
authors.initials: PE
authors.lastname: de Haas
authors.forename: Dirk H
authors.initials: DH
authors.lastname: Mueller
authors.forename: Paul D
authors.initials: PD
authors.lastname: van Helden
authors.forename: Lawrence
authors.initials: L
authors.lastname: Mwenge
authors.forename: Ab
authors.initials: A
authors.lastname: Schaap
authors.forename: Clarissa
authors.initials: C
authors.lastname: Kruger
authors.forename: Nicolaas C
authors.initials: NC
authors.lastname: Gey van Pittius
authors.forename: Katherine
authors.initials: K
authors.lastname: Lawrence
authors.forename: Nulda
authors.initials: N
authors.lastname: Beyers
authors.forename: Peter
authors.initials: P
authors.lastname: Godfrey-Faussett
authors.forename: Helen
authors.initials: H
authors.lastname: Ayles
mesh_terms: D001431:Bacteriological Techniques / Q000191:economics / Q000379:methods*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D013019:South Africa; D013997:Time Factors; D014376:Tuberculosis / Q000175:diagnosis*; D015024:Zambia