title: [Relationship between sex steroids and bone density in elderly men].
abstract: OBJECTIVE
  To determine the relationship between serum estradiol level (ESL) and testosterone serum level (TSL) with bone mineral density (BMD) in elderly men.
  
  
  METHODS
  Cross-sectional study including 127 healthy men aged 60 years and over. BMD of the lumbar spine and femoral neck were measured. ESL, TSL and sex hormone binding globulin were estimated by radioimmunoassay. Free testosterone level (FTL) was calculated.
  
  
  RESULTS
  The ESL and BMD correlation at the spine was r = 0.288, (p < 0.01) and at the femoral neck was r = 0.224, (p < 0.01). These correlations remained significant after adjustment for BMI and age. By contrast, no correlation was found between TSL and BMD. However FTL were associated with BMD at the spine (r = 0.288, p < 0.01) and at the femoral neck (r = 0.190, p < 0.05).
  
  
  CONCLUSIONS
  ESL and FTL are associated with BMD in elderly men. This effect may be partially mediated by the peripheral conversion of testosterone into estradiol.
authors.affiliation: Unidad de Investigación de Enfermedades Endocrinas, Diabetes y Metabolismo, Departamento de Radiología e Imagen, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Basurto
authors.forename: Renata
authors.initials: R
authors.lastname: Saucedo
authors.forename: Rosa
authors.initials: R
authors.lastname: Galván
authors.forename: Columba
authors.initials: C
authors.lastname: Vargas
authors.forename: Nydia
authors.initials: N
authors.lastname: Córdova
authors.forename: Sandra
authors.initials: S
authors.lastname: Campos
authors.forename: Sara
authors.initials: S
authors.lastname: Vega
authors.forename: Erika
authors.initials: E
authors.lastname: Moreno
authors.forename: Francisco
authors.initials: F
authors.lastname: Avelar
authors.forename: Arturo
authors.initials: A
authors.lastname: Zárate
mesh_terms: D000368:Aged; D015519:Bone Density; D003430:Cross-Sectional Studies; D004958:Estradiol / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013739:Testosterone / Q000097:blood*
chemical_list: D013739:Testosterone; D004958:Estradiol