title: The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506 reveals several gene clusters responsible for the biosynthesis of toxins and secondary metabolites.
abstract: We report a draft sequence of the genome of Oscillatoria sp. PCC 6506, a cyanobacterium that produces anatoxin-a and homoanatoxin-a, two neurotoxins, and cylindrospermopsin, a cytotoxin. Beside the clusters of genes responsible for the biosynthesis of these toxins, we have found other clusters of genes likely involved in the biosynthesis of not-yet-identified secondary metabolites.
authors.affiliation: Laboratoire Charles Friedel, UMR CNRS 7223, ENSCP Chimie ParisTech, 11 Rue Pierre et Marie Curie, 75231 Paris Cedex 05, France. annick-mejean@enscp.fr
authors.forename: Annick
authors.initials: A
authors.lastname: Méjean
authors.forename: Rabia
authors.initials: R
authors.lastname: Mazmouz
authors.forename: Stéphane
authors.initials: S
authors.lastname: Mann
authors.forename: Alexandra
authors.initials: A
authors.lastname: Calteau
authors.forename: Claudine
authors.initials: C
authors.lastname: Médigue
authors.forename: Olivier
authors.initials: O
authors.lastname: Ploux
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics* / Q000502:physiology; D054300:Oscillatoria / Q000235:genetics*
chemical_list: D001427:Bacterial Toxins