title: RefProtDom: a protein database with improved domain boundaries and homology relationships.
abstract: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.
  
  
  BACKGROUND
  RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a.
authors.affiliation: Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA. miledywgonzalez@gmail.com
authors.forename: Mileidy W
authors.initials: MW
authors.lastname: Gonzalez
authors.forename: William R
authors.initials: WR
authors.lastname: Pearson
mesh_terms: D030562:Databases, Protein; D017434:Protein Structure, Tertiary; D011506:Proteins; D012984:Software
chemical_list: D011506:Proteins