Low measles seropositivity rate among children and young adults: a sero-epidemiological study in southern China in 2008.
To obtain sero-epidemiological profile and develop optimal strategies to promote measles elimination, we conducted a measles seroprevalence study using stratified sampling method in Guangzhou, southern China in 2008. 4036 samples were analyzed by the enzyme-linked immunosorbent assay method and the overall sero-positive rate of measles antibody was 70.6% (95% CI 69.2-72.0%). Positive seroprevalences differed among age groups (P=0.000) and a W-curve distribution was observed. The 15-29 years group had the low positive rate of 58.8% (95% CI 54.9-62.7%). Catch-up vaccination campaigns should be promoted among susceptible population of ≤ 29 year olds including women of childbearing age.
Fu
Chuanxi
C
Department of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, 1838 Guangzhou Dadao Road North, Guangzhou 510515, PR China.
Xu
Jianxiong
J
Liu
Weibin
W
Zhang
Wei
W
Wang
Ming
M
Nie
Jun
J
Rüdiger
von Kries
vK
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008457:Measles / Q000453:epidemiology*; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D055815:Young Adult
D000914:Antibodies, Viral