title: [A case of cardiac sarcoidosis occurring during combination therapy by IFN alpha and ribavirin for chronic hepatitis C].
abstract: A 72-year-old woman received combination therapy with peginterferon alpha and ribavirin for treatment of chronic hepatitis C. Approximately 40 weeks after starting treatment, she developed an eruption in the left inner canthus and sarcoidosis was diagnosed after biopsy of the eruption. Combination therapy was discontinued, and further detailed examinations revealed bilateral hilar lymphadenopathy, uveitis, and complete atrioventricular block. A permanent cardiac pacemaker was implanted, and her sarcoidosis improved upon administration of corticosteroids.
authors.affiliation: Department of Internal Medicine, Nishimino Kosei Hospital. iwashita@nishimino.gfkosei.or.jp
authors.forename: Masahide
authors.initials: M
authors.lastname: Iwashita
authors.forename: Teruo
authors.initials: T
authors.lastname: Maeda
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tagami
authors.forename: Naoki
authors.initials: N
authors.lastname: Watanabe
authors.forename: Jun
authors.initials: J
authors.lastname: Takada
authors.forename: Takahiko
authors.initials: T
authors.lastname: Asano
authors.forename: Hiroo
authors.initials: H
authors.lastname: Hatakeyama
authors.forename: Takao
authors.initials: T
authors.lastname: Hayashi
authors.forename: Shinji
authors.initials: S
authors.lastname: Nishiwaki
authors.forename: Koshiro
authors.initials: K
authors.lastname: Saito
mesh_terms: D000368:Aged; D000998:Antiviral Agents / Q000009:adverse effects*; D009202:Cardiomyopathies / Q000209:etiology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects*; D012254:Ribavirin / Q000009:adverse effects*; D012507:Sarcoidosis / Q000209:etiology*
chemical_list: D000998:Antiviral Agents; D016898:Interferon-alpha; D012254:Ribavirin