Prefrontal mediation of age differences in cognitive reappraisal.
Despite cognitive and physical declines, it has been suggested that older adults remain able to regulate their emotions effectively. However, whether this is true for all emotion regulation processes has not been established. We hypothesized that cognitive reappraisal, a form of emotion regulation requiring intact cognitive control ability, may be compromised in older age, and that this age difference would be mediated by reduced activation in prefrontal cortex (PFC). Sixteen younger and 15 older adults used gaze-directed reappraisal to increase and decrease emotion in response to unpleasant pictures. This was compared with simply viewing the pictures. Relative to younger adults, older adults were less successful using reappraisal to decrease unpleasant emotion but more successful using reappraisal to increase unpleasant emotion. They also exhibited reduced activation in dorsomedial and left ventrolateral prefrontal cortex. Importantly, activation in these regions differentially mediated the effect of age on emotion. This pattern confirms the importance of cognitive control in reappraising unpleasant situations and suggests that older age may (but does not always) confer effective emotion regulation.
Opitz
Philipp C
PC
Tufts University, Medford, MA 02155, USA.
Rauch
Lindsay C
LC
Terry
Douglas P
DP
Urry
Heather L
HL
D000293:Adolescent; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D001288:Attention / Q000502:physiology; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology*; D004644:Emotions / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D017008:Negotiating; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D017397:Prefrontal Cortex / Q000098:blood supply / Q000502:physiology*; D011795:Surveys and Questionnaires; D055815:Young Adult
D010100:Oxygen