title: Increased mean platelet volume in patients with aortic stenosis.
abstract: BACKGROUND
  Systemic thromboembolism is a serious complication in patients with aortic stenosis (AS). Previous studies have demonstrated that platelet activation occurs in patients with AS. The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with AS.
  
  
  METHODS
  The study group consisted of 43 patients with AS. An age-, gender-, and body mass index-matched control group consisted of 35 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants.
  
  
  RESULTS
  Mean platelet volume was significantly higher among patients with AS when compared with the control group (8.7 ± 1.0 vs 7.9 ± 0.9 fL, respectively; P = .001).
  
  
  CONCLUSIONS
  We have shown that MPV was significantly elevated in patients with AS compared to control participant.
authors.affiliation: Department of Cardiology, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey. drercanvarol@yahoo.com
authors.forename: Ercan
authors.initials: E
authors.lastname: Varol
authors.forename: Akif
authors.initials: A
authors.lastname: Arslan
authors.forename: Habil
authors.initials: H
authors.lastname: Yucel
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozaydin
authors.forename: Dogan
authors.initials: D
authors.lastname: Erdogan
authors.forename: Abdullah
authors.initials: A
authors.lastname: Dogan
mesh_terms: D001024:Aortic Valve Stenosis / Q000097:blood* / Q000000981:diagnostic imaging; D001792:Blood Platelets / Q000473:pathology*; D004452:Echocardiography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015539:Platelet Activation; D010976:Platelet Count; D013923:Thromboembolism / Q000097:blood* / Q000000981:diagnostic imaging