Race, socioeconomic status, and response to methotrexate treatment of ectopic pregnancy in an urban population.
On the basis of the documented racial disparities in ectopic pregnancy incidence and mortality we hypothesized that African-American women with ectopic pregnancy would be more likely than white women to have treatment failure with methotrexate. In this retrospective cohort study, a racial disparity in methotrexate effectiveness was not found, but a significant relationship between low socioeconomic status and methotrexate failure was demonstrated.
Butts
Samantha F
SF
Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. sbutts@obgyn.upenn.edu
Gibson
Erika
E
Sammel
Mary D
MD
Shaunik
Alka
A
Rudick
Brianna
B
Barnhart
Kurt
K
D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D004305:Dose-Response Relationship, Drug; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D015994:Incidence; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy* / Q000453:epidemiology / Q000208:ethnology*; D044469:Racial Groups / Q000706:statistics & numerical data; D012923:Social Class; D017211:Treatment Failure; D016896:Treatment Outcome; D014505:Urban Population / Q000706:statistics & numerical data; D055815:Young Adult
D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate