title: [Intentional poisoning with ACE inhibitors. Emergeny Hospital Iaşi].
abstract: Regarding angiotensin-converting enzyme inhibitors (ACEI) poisoning, only few data are available in the last decade literature. In the previous couple of years especially isolated case reports were published.
  
  
  METHODS
  We analyzed retrospectively all the patients with acute ACEI poisoning admitted in Iaşi Internal Medicine and Toxicology Clinic between 2004 and 2009.
  
  
  RESULTS
  17 cases of poisoning were recorded (enalapril-9 cases, captopril-3 cases, perindopril-3 cases, lisinopril-2 cases). All the poisonings were intentional. A favorable outcome was consistently observed, and were recorded no sequelae or death in this study. The main complain was hypotension, required fluid administration, only one case with 500 mg enalaprilum and severe hypotension required injection of vasopressive amines. No abnormal renal function and no angioedema were noted.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi Facultatea de Medicină, Spitalul Clinic de Urgenţe Sf. Ioan Iaşi, Clinica de Medicină Internă şi Toxicologie Facultatea de Medicină.
authors.forename: Victoriţa
authors.initials: V
authors.lastname: Sorodoc
authors.forename: L
authors.initials: L
authors.lastname: Sorodoc
authors.forename: Cătălina
authors.initials: C
authors.lastname: Lionte
authors.forename: E
authors.initials: E
authors.lastname: Gazzi
authors.forename: Irina Maria
authors.initials: IM
authors.lastname: Jaba
authors.forename: O C
authors.initials: OC
authors.lastname: Mungiu
mesh_terms: D000328:Adult; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000506:poisoning*; D000959:Antihypertensive Agents / Q000506:poisoning*; D002216:Captopril / Q000506:poisoning; D004656:Enalapril / Q000506:poisoning; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000628:therapy; D017706:Lisinopril / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D020913:Perindopril / Q000506:poisoning; D012189:Retrospective Studies; D013406:Suicide, Attempted / Q000706:statistics & numerical data*; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D004656:Enalapril; D002216:Captopril; D017706:Lisinopril; D020913:Perindopril