title: The timing of definitive fixation for major fractures in polytrauma--a matched-pair comparison between a US and European level I centres: analysis of current fracture management practice in polytrauma.
abstract: OBJECTIVE
  Early definitive stabilisation is usually the treatment of choice for major fractures in polytrauma patients. Modifications may be made when patients are in critical condition, or when associated injuries dictate the timing of surgery. The current study investigates whether the timing of fracture treatment is different in different trauma systems.
  
  
  METHODS
  Consecutive patients treated a Level I trauma centre were documented (Group US) and a matched-pair group was gathered from the German Trauma Registry (Group GTR).
  
  
  METHODS
  New Injury Severity Score (NISS)>16, >2 major fractures and >1 organ/soft tissue injury. The timing and type of surgery for major fractures was recorded, as were major complications.
  
  
  RESULTS
  114 patients were included, n=57 Group US (35.1% F, 64.9% M, mean age: 44.1 yrs±16.49, mean NISS: 27.4±8.65, mean ICU stay: 10±7.49) and n=57 Group GTR (36.8% F, 63.1% M, mean age: 41.2 yrs±15.35, mean NISS: 29.4±6.88, mean ICU stay: 15.6±18.25). 44 (57.1%) out of 77 fractures in Group US received primary definitive fracture fixation compared to 61 (65.5%) out of 93 fractures in Group GTR (n.s.). The average duration until definitive treatment was comparable in all major extremity fractures (pelvis: 5 days±2.8 Group US, 7.1 days±9.6 Group GTR (n.s.), femur: 7.9 days±8.3 Group US, 5.5 days±7.9 (n.s.), tibia: 6.2 days±5.6 Group US, 6.2 days±9.1 Group GTR (n.s.), humerus: 5 days±3.7 Group US, 6.6 days±6.1 Group GTR (n.s.), radius: 6 days±4.7 Group US, 6.1 days±8.7 Group GTR (n.s.).
  
  
  CONCLUSIONS
  The current matched-pair analysis demonstrates that the timing of initial definitive fixation of major fractures is comparable between the US and Europe. Certain fractures are stabilised internally in a staged fashion regardless the trauma system, thus discounting previous apparent contradictions.
authors.affiliation: Department of Orthopaedic Surgery, Division of Trauma, University of Pittsburgh, Pittsburgh, USA. schreibervm@upmc.edu
authors.forename: Verena M
authors.initials: VM
authors.lastname: Schreiber
authors.forename: Ivan S
authors.initials: IS
authors.lastname: Tarkin
authors.forename: Frank
authors.initials: F
authors.lastname: Hildebrand
authors.forename: Sophie
authors.initials: S
authors.lastname: Darwiche
authors.forename: Roman
authors.initials: R
authors.lastname: Pfeifer
authors.forename: Jaques
authors.initials: J
authors.lastname: Chelly
authors.forename: Peter
authors.initials: P
authors.lastname: Giannoudis
authors.forename: Hans-Christoph
authors.initials: HC
authors.lastname: Pape
mesh_terms: D000328:Adult; D005060:Europe; D005260:Female; D005592:Fracture Fixation / Q000379:methods*; D050723:Fractures, Bone / Q000601:surgery*; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D016555:Matched-Pair Analysis; D009104:Multiple Trauma / Q000601:surgery*; D013997:Time Factors; D014193:Trauma Centers; D014481:United States