Fetal MR imaging evidence of prolonged apparent diffusion coefficient decrease in fetal death.
We report 2 fetal MR imaging cases at 22 wkGA with cerebral bright DWI and low ADC, 8 and 19 days after documented fetal death. These observations illustrate that decreased diffusion can be present weeks after injury onset, and its presence cannot be used to time injury onset within 1 week, which could significantly impact determination of the proximate cause of fetal brain injury in future cases.
Tarui
T
T
Departments of Neurology, Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA. tomo.tarui@childrens.harvard.edu
Khwaja
O S
OS
Estroff
J A
JA
Robinson
J N
JN
Grant
P E
PE
D000328:Adult; D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D005313:Fetal Death / Q000473:pathology*; D005330:Fetofetal Transfusion / Q000473:pathology*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014427:Twins