Cell polarity: keeping worms LeGaL.
The protein Lethal giant larvae (LGL) regulates cell polarity in diverse animal models. Now, an LGL orthologue has been identified in the worm Caenorhabditis elegans and is shown to function redundantly with a worm-specific polarity protein, PAR-2.
Prehoda
Kenneth E
KE
Institute of Molecular Biology, University of Oregon, 1370 Franklin Boulevard, Eugene, OR 97403, USA.
Bowerman
Bruce
B
D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology* / Q000378:metabolism; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism; D016764:Cell Polarity; D011493:Protein Kinase C / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases
D029742:Caenorhabditis elegans Proteins; C512642:par-6 protein, C elegans; C097238:PAR-3 protein, C elegans; D017346:Protein Serine-Threonine Kinases; C115015:PKC-3 protein; D011493:Protein Kinase C