Studies on highly regio- and stereoselective hydration of 1,2-allenylic sulfoxides.
A highly regio- and stereoselective hydration of 1,2-allenylic sulfoxides in which proton served as the electrophile was reported. Through the X-ray diffraction study, it was concluded that the reaction may proceed via a 5-membered cyclic intermediate following by attack of the (-)OH at the sulfur atom.
Fang
Zhao
Z
Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, , Zhejiang, PR China.
Zhou
Chao
C
Fu
Chunling
C
Ma
Shengming
S