title: Cytology of nasal mucosa, olfactometry and rhinomanometry in patients after CO2 laser mucotomy in inferior turbinate hypertrophy.
abstract: To evaluate the cytology of nasal mucosa and sense of smell and nasal patency in patients underwent carbon dioxide laser turbinoplasty (CO2 laser mucotomy) due to chronic nasal hypertrophy. 46 patients with inferior turbinate hypertrophy underwent complete laryngological examination, anterior rhinomanometry, olfactory measurements and cytology of nasal mucous which were performed before and 3 months after CO2 laser mucotomy. Laser mucotomy was performed under local anesthesia. Cytograms revealed significant changes in cell proportion before and after the surgery. Goblet cells predominated in nasal smears before the laser mucotomy. An average percentage of eosinophils in evaluated cytograms before the surgery was 2.1%. Three months after laser mucotomy we observed decrease in goblet cells proportion (the mean range of goblet cells was 16.4%) in nasal cytology. We have also observed improvement in olfactory function, however only in 7 patients (20.6%). The mean value of total nasal airway resistance (NAR) before treatment was 0.98+/-0.24 Pa/cm3/s at 75 Pa. Rhinomanometry after 3 months showed a reduction in mean total resistance from the pretreatment level to 0.77 Pa/cm3/s. We believe that CO2 laser mucotomy is an efficacious, minimally invasive and easy to use treatment of inferior turbinate hypertrophy which is performed under local anesthesia with little discomfort for the patient and does not require hospitalization.
authors.affiliation: Department of Otolaryngology, Medical University of Bialystok, Poland. kasacka@umwb.edu.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Olszewska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Sieskiewicz
authors.forename: Irena
authors.initials: I
authors.lastname: Kasacka
authors.forename: Marek
authors.initials: M
authors.lastname: Rogowski
authors.forename: Marlena
authors.initials: M
authors.lastname: Zukowska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Soroczyńska
authors.forename: Justyna
authors.initials: J
authors.lastname: Rutkowska
mesh_terms: D000328:Adult; D000403:Airway Resistance; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000473:pathology / Q000601:surgery; D054020:Lasers, Gas; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000166:cytology*; D015508:Nasal Obstruction / Q000473:pathology / Q000601:surgery; D025363:Rhinomanometry / Q000379:methods*; D012903:Smell; D016896:Treatment Outcome; D014420:Turbinates / Q000473:pathology / Q000601:surgery; D055815:Young Adult