title: [3-azabicyclo[3.1.0]hex-1-yl]phenyl-benzenesulfonamides as selective dopamine D3 antagonists.
abstract: A new class of azabicyclo[3.1.0]benzenesulfonamides is presented as selective dopamine D3 antagonists together with SAR and selectivity data.
authors.affiliation: Neurosciences Centre of Excellence, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy. fabrizio.micheli@aptuit.com
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Micheli
authors.forename: Dieter
authors.initials: D
authors.lastname: Hamprecht
authors.forename: Giorgio
authors.initials: G
authors.lastname: Bonanomi
authors.forename: Romano
authors.initials: R
authors.lastname: Di Fabio
authors.forename: Daniele
authors.initials: D
authors.lastname: Donati
authors.forename: Gabriella
authors.initials: G
authors.lastname: Gentile
authors.forename: Christian
authors.initials: C
authors.lastname: Heidbreder
authors.forename: Adolfo
authors.initials: A
authors.lastname: Prandi
authors.forename: Luca
authors.initials: L
authors.lastname: Tarsi
authors.forename: Silvia
authors.initials: S
authors.lastname: Terreni
mesh_terms: D001554:Benzene / Q000737:chemistry / Q000494:pharmacology; D018492:Dopamine Antagonists / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D050637:Receptors, Dopamine D3 / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D018492:Dopamine Antagonists; D050637:Receptors, Dopamine D3; D013449:Sulfonamides; D001554:Benzene