title: Practical iron-catalyzed dehalogenation of aryl halides.
abstract: An operationally simple iron-catalyzed hydrodehalogenation of aryl halides has been developed with 1 mol% Fe(acac)(3) and commercial t-BuMgCl as reductant. The mild reaction conditions (THF, 0 degrees C, 1.5 h) effect rapid chemoselective dehalogenation of (hetero)aryl halides (I, Br, Cl) and tolerate F, Cl, OR, SR, CN, CO(2)R, and vinyl groups.
authors.affiliation: Department of Chemistry, University of Cologne, Greinstr. 4, 50939 Koeln, Germany.
authors.forename: Waldemar Maximilian
authors.initials: WM
authors.lastname: Czaplik
authors.forename: Sabine
authors.initials: S
authors.lastname: Grupe
authors.forename: Matthias
authors.initials: M
authors.lastname: Mayer
authors.forename: Axel
authors.initials: A
authors.lastname: Jacobi von Wangelin
mesh_terms: D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D005290:Ferric Compounds; D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated