Haemophilus influenzae outer membrane protein P6 molecular characterization may not differentiate all strains of H. Influenzae from H. haemolyticus.
Distinguishing nontypeable Haemophilus influenzae and Haemophilus haemolyticus isolates by outer membrane protein (OMP) P6 gene sequencing is complicated by sequence variants in isolates. Further testing using RapID NH and multilocus sequence analysis may not help identify some isolates. Translated OMP P6 gene sequences are not conserved among all isolates presumed to be H. influenzae.
Chang
Arthur
A
Rochester General Hospital, Rochester General Research Institute, Center for Infectious Diseases and Immunology, Rochester, NY 14621, USA.
Adlowitz
Diana G
DG
Yellamatty
Edna
E
Pichichero
Michael
M
D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001431:Bacteriological Techniques / Q000379:methods*; D002675:Child, Preschool; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D014644:Genetic Variation; D006190:Haemophilus / Q000145:classification* / Q000235:genetics*; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000382:microbiology; D018073:Haemophilus Vaccines / Q000235:genetics*; D006801:Humans; D007223:Infant; D012680:Sensitivity and Specificity; D017422:Sequence Analysis, DNA
D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial; D018073:Haemophilus Vaccines; C069990:P6 outer membrane protein, Haemophilus