title: A retrospective study in 21 Shiba dogs with chronic enteropathy.
abstract: We retrospectively studied the clinical and laboratory features and outcomes of chronic enteropathy in Shiba dogs. Among 99 dogs with chronic enteropathy, 21 Shiba dogs (21%) were included in the study (odds ratio, 7.14). No significant differences were seen in signalment, clinical signs, symptoms or laboratory profiles between the Shiba and non-Shiba groups. Severe histopathological lesions in the duodenum were a common finding in the Shiba group. The median overall duration of survival in the Shiba group was 74 days, while that of the dogs in the non-Shiba group could not be determined because more than half of the cases remained alive at the end of this study. The difference between the groups was statistically significant (P<0.0001). The 6-month and 1-year survival rates for the Shiba group were 46% and 31%, respectively. Conversely, the 6-month, 1-year and 3-year survival rates for the non-Shiba group were 83%, 74% and 67%. The results obtained here demonstrated that the Shiba dog is predisposed to chronic enteropathy and shows severe duodenum lesions and poor outcomes, indicating a breed-specific disease.
authors: Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
authors: Aki
authors: A
authors: Ohmi
authors: Koichi
authors: K
authors: Ohno
authors: Kazuyuki
authors: K
authors: Uchida
authors: Hiroyuki
authors: H
authors: Nakayama
authors: Yuko
authors: Y
authors: Koshino-Goto
authors: Kenjiro
authors: K
authors: Fukushima
authors: Masashi
authors: M
authors: Takahashi
authors: Ko
authors: K
authors: Nakashima
authors: Yasuhito
authors: Y
authors: Fujino
authors: Hajime
authors: H
authors: Tsujimoto
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004283:Dog Diseases / Q000235:genetics / Q000473:pathology*; D004285:Dogs; D004751:Enteritis / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D005260:Female; D020022:Genetic Predisposition to Disease; D008297:Male; D012189:Retrospective Studies