Thin-walled graphitic nanocages as a unique platform for amperometric glucose biosensor.
A thin-walled graphitic nanocages material with well-developed graphitic structure, large specific surface area and pronounced mesoporosity was synthesized and used to construct a sensing interface for an amperometric glucose biosensor, showing a high and reproducible sensitivity of 13.3 μA mM(-1) cm(-2), linear dynamic range of 0.02-6.2 mM, and fast response time of 5 s. It was successfully used to accurately detect glucose in human serum with effective discrimination to common interference species such as dopamine, ascorbic acid, acetaminophen, and uric acid.
Guo
Chun Xian
CX
School of Chemical and Biomedical Engineering & Center for Advanced Bionanosystems, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457.
Sheng
Zhao Min
ZM
Shen
Yi Qiang
YQ
Dong
Zhi Li
ZL
Li
Chang Ming
CM
D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D008839:Microelectrodes; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D006108:Graphite; D005947:Glucose