[Informative value of the VCS parameters of peripheral blood neutrophils in the evaluation of status of patients with recurrent and metastatic cervical cancer].
The total values of white blood cells (WBC), the absolute and relative neutrophil counts, neutrophil VCS parameters: MVNe (volume), MCNe (conductivity), and MSNe (light scattering) were studied in 70 patients with recurrent and metastatic cancer of the cervix uteri, by using a LH-500 hematology analyzer (Beckman Coulter). The blood from 35 apparently healthy women served as a control. The magnitude of changes in MVNe and in the intensity of MSNe was found to increase in patients when the level of WBC and the content of neutrophils were elevated. Neutrophil VCS parameters, MVNe and MSNe in particular, may serve as an objective and sensitive indicator of condition severity in cancer patients.
Gus'kova
N K
NK
Nerodo
G A
GA
Levchenko
N E
NE
Gus'kova
E A
EA
Zakharchenko
V R
VR
Demicheva
A A
AA
D048429:Cell Size; D004553:Electric Conductivity; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008027:Light; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009504:Neutrophils / Q000473:pathology* / Q000502:physiology; D012542:Scattering, Radiation; D012720:Severity of Illness Index; D002583:Uterine Cervical Neoplasms / Q000097:blood* / Q000473:pathology