title: Prenatal diagnosis and follow-up of 23 cases of cardiac tumors.
abstract: OBJECTIVE
  To evaluate the prenatal characteristics and postnatal outcome of cardiac tumors diagnosed at two prenatal Polish cardiology centers.
  
  
  METHODS
  Descriptive analysis of 23 fetuses with cardiac tumors (12 multiple and 11 single) diagnosed over 16 years (from 1993 to 2009). Congestive heart failure was diagnosed when the cardiovascular profile score was seven or less.
  
  
  RESULTS
  Associated structural congenital heart defects were present in three fetuses, extracardiac anomalies in three, and chromosomal anomalies in two. Congestive heart failure developed in five cases. Perinatal survival was not different between cases with and without cardiac failure (2/5 vs 12/18, p = 0.28). The main ultrasonographic signs observed prenatally in association with cardiac tumors were cardiomegaly, left ventricular outflow tract obstruction, pericardial effusion, and hypokinesis. A diagnosis of tuberous sclerosis was eventually made in all 12 fetuses with multiple tumors. Perinatal death occurred in 4/11 cases with single tumors and in 5/12 with multiple tumors (p = 0.57). Surgical resection of the tumor was performed in 3/11 neonates with single tumors (histopathologically: rhabdomyoma, teratoma, and fibroma) and in 2/12 with multiple tumors (both rhabdomyomas).
  
  
  CONCLUSIONS
  Survival is not different between neonates with single and multiple tumors and between those with and without congestive heart failure.
authors: Fetal Echocardiography Laboratory, Department of Pediatric Cardiology, 2nd Chair of Pediatrics, Medical University of Lodz, Lodz, Poland. kasiajarosik@wp.pl
authors: Katarzyna
authors: K
authors: Niewiadomska-Jarosik
authors: Jerzy
authors: J
authors: Stańczyk
authors: Katarzyna
authors: K
authors: Janiak
authors: Piotr
authors: P
authors: Jarosik
authors: Jacek Jan
authors: JJ
authors: Moll
authors: Justyna
authors: J
authors: Zamojska
authors: Maria
authors: M
authors: Respondek-Liberska
mesh_terms: D000328:Adult; D000465:Algorithms; D019091:Critical Pathways; D005260:Female; D005350:Fibroma / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000150:complications / Q000000981:diagnostic imaging*; D006338:Heart Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D050498:Live Birth; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D012207:Rhabdomyoma / Q000000981:diagnostic imaging / Q000473:pathology; D016019:Survival Analysis; D013724:Teratoma / Q000000981:diagnostic imaging / Q000473:pathology; D014402:Tuberous Sclerosis / Q000000981:diagnostic imaging / Q000473:pathology; D016216:Ultrasonography, Prenatal; D055815:Young Adult