Meiotic kinetochores get pushed aside by a CLS act.
Kinetochores link microtubules to DNA and provide force critical for chromosome segregation in mitosis. New data show that kinetochores are not necessary for acentrosomal meiotic chromosome segregation in Caenorhabditis elegans. Instead, CLS-2 (CLASP) generates a mid-zone bundle of microtubules that are suggested to act in pushing the chromosomes apart.
Han
Xue
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Srayko
Martin
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D000705:Anaphase / Q000502:physiology; D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology / Q000502:physiology; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism; D020090:Chromosome Segregation / Q000502:physiology*; D005260:Female; D018386:Kinetochores / Q000502:physiology*; D008540:Meiosis / Q000502:physiology*; D008677:Metaphase / Q000502:physiology; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D008954:Models, Biological; D009865:Oocytes / Q000166:cytology / Q000502:physiology
D029742:Caenorhabditis elegans Proteins; D008869:Microtubule-Associated Proteins