[Study on selenium exposure level related to cognitive function in rural elderly people].
OBJECTIVE
To know the relationship between selenium exposure level and cognitive function and its influencing factors in rural elderly people.


METHODS
A cross-sectional survey of 200 local rural elderly people were conducted by using dietary questionnaire and six cognitive questionnaires. The local environment samples were collected including food and nail and blood sample of study individuals. The trace amount of selenium were determined with 2, 3-diaminonaphthalenet fluorometric determination. Multiple stepwise regression was used to examine the association between selenium exposure level and the composite Z score adjusting for age, gender, education, and other factors that might influence the cognitive scores.


RESULTS
There were significant positively relationships between three selenium exposure indexes. The results showed that food selenium intake level and blood selenium level could significantly affected the Z score after adjusting age, education and other factors by using multiple stepwise regression analysis (P < 0.001).


CONCLUSIONS
Lower selenium exposure level maybe associated with lower cognitive function in rural elderly people.
Cheng
Yibin
Y
Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China. ybcheng123@163.com
Jin
Yinlong
Y
Ma
Feng
F
Liang
Chaoke
C
Liu
Ya
Y
Bian
Jianchao
J
Li
Ping
P
Gao
Sujuan
S
D000368:Aged; D002681:China / Q000453:epidemiology; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000453:epidemiology* / Q000378:metabolism; D003430:Cross-Sectional Studies; D004034:Diet Surveys; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000737:chemistry; D012423:Rural Health; D012494:Sampling Studies; D012643:Selenium / Q000008:administration & dosage* / Q000097:blood / Q000378:metabolism*; D011795:Surveys and Questionnaires
D012643:Selenium