title: Inappropriate sinus tachycardia - successful treatment with ivabradine.
abstract: Inappropriate sinus tachycardia (IST) is characterised by an exaggerated increase of heart rate in response to normal physiologic demands. Therapeutic options including medical and radiofrequency ablation interventions are still under debate. Ivabradine inhibits spontaneous pacemaker activity of the sinus node by selectively blocking If channels of pacemaker cells. Here we present a case of a patient with IST, who was successfully treated with ivabradine after various ineffective therapeutic approaches.
authors: Department of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey. drozlemoz@mynet.com
authors: Ozlem Ozcan
authors: OO
authors: Celebi
authors: Alper
authors: A
authors: Canbay
authors: Savas
authors: S
authors: Celebi
authors: Sinan
authors: S
authors: Aydogdu
authors: Erdem
authors: E
authors: Diker
mesh_terms: D000293:Adolescent; D001552:Benzazepines / Q000008:administration & dosage*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D054815:Cyclic Nucleotide-Gated Cation Channels / Q000008:administration & dosage*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D000077550:Ivabradine; D013318:Stroke Volume / Q000187:drug effects; D013616:Tachycardia, Sinus / Q000188:drug therapy* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D001552:Benzazepines; D002317:Cardiovascular Agents; D054815:Cyclic Nucleotide-Gated Cation Channels; D000077550:Ivabradine