Kinetic resolution of racemic 2,3-allenoates by organocatalytic asymmetric 1,3-dipolar cycloaddition.
The kinetic resolution of racemic 2,3-allenoates was realized via 1,3-dipolar cycloaddition by using a bisphosphoric acid catalyst, affording the optically active 2,3-allenoates and 3-methylenepyrrolidine derivatives in high yields and enantioselectivities.
Yu
Jie
J
Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
Chen
Wei-Jie
WJ
Gong
Liu-Zhu
LZ
D002384:Catalysis; D003500:Cyclization; D007700:Kinetics; D008958:Models, Molecular; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013237:Stereoisomerism
D009281:Naphthalenes; C110055:allenolic acid