title: Roles of calcineurin B-like protein-interacting protein kinases in innate immunity in rice.
abstract: Cytosolic free Ca(2+) mobilization induced by microbe/pathogen-associated molecular patterns (MAMPs/PAMPs) play key roles in plant innate immunity. However, components involved in Ca(2+) signaling pathways still remain to be identified and possible involvement of the CBL (calcineurin B-like proteins)-CIPK (CBL-interacting protein kinases) system in biotic defense signaling has yet to be clarified. Recently we identified two CIPKs, OsCIPK14 and OsCIPK15, which are rapidly induced by MAMPs, involved in various MAMP-induced immune responses including defense-related gene expression, phytoalexin biosynthesis and hypersensitive cell death. MAMP-induced production of reactive oxygen species as well as cell browning were also suppressed in OsCIPK14/15-RNAi transgenic cell lines. Possible molecular mechanisms and physiological functions of the CIPKs in plant innate immunity are discussed.
authors: Department of Applied Biological Science, Tokyo University of Science, Noda, Chiba, Japan.
authors: Takamitsu
authors: T
authors: Kurusu
authors: Jumpei
authors: J
authors: Hamada
authors: Haruyasu
authors: H
authors: Hamada
authors: Shigeru
authors: S
authors: Hanamata
authors: Kazuyuki
authors: K
authors: Kuchitsu
mesh_terms: D019703:Calcineurin / Q000235:genetics / Q000276:immunology*; D016923:Cell Death; D018506:Gene Expression Regulation, Plant; D007113:Immunity, Innate; D012275:Oryza / Q000235:genetics / Q000276:immunology*; D057865:Plant Immunity; D010940:Plant Proteins / Q000235:genetics / Q000276:immunology*; D030821:Plants, Genetically Modified / Q000235:genetics / Q000276:immunology; D011494:Protein Kinases / Q000235:genetics / Q000276:immunology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D012717:Sesquiterpenes / Q000378:metabolism; D015398:Signal Transduction; D000094162:Phytoalexins
chemical_list: D010940:Plant Proteins; D017382:Reactive Oxygen Species; D012717:Sesquiterpenes; D011494:Protein Kinases; D019703:Calcineurin; D000094162:Phytoalexins