title: Asymmetric transfer hydrogenation of ketones catalyzed by rhodium complexes containing amino acid triazole ligands.
abstract: Active and selective catalysts for the asymmetric reduction of ketones, under transfer hydrogenation conditions, were obtained by combining [RhCl(2)Cp*](2), with a series of l-amino acid thioamide ligands functionalized with 1,2,3-triazoles. The obtained secondary alcohol products were formed with up to 93% ee.
authors: Department of Organic Chemistry, Stockholm University, The Arrhenius Laboratory, SE-10691 Stockholm, Sweden.
authors: Fredrik
authors: F
authors: Tinnis
authors: Hans
authors: H
authors: Adolfsson
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry*
chemical_list: D007659:Ketones; D008024:Ligands; D014230:Triazoles; D012238:Rhodium