Nickel-catalyzed C-O activation of phenol derivatives with potassium heteroaryltrifluoroborates.
A general method based on nickel-catalyzed C-O activation of various phenol derivatives with potassium (hetero)aryltrifluoroborates has been developed. A large number of heterobiaryls can be easily obtained with yields up to 99% using methanesulfonate cross-coupling partners.
Molander
Gary A
GA
Roy and Diana A. Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA. gmolandr@sas.upenn.edu
Beaumard
Floriane
F
D001881:Borates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D017611:Fluorine Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D019800:Phenol / Q000737:chemistry*; D017680:Potassium Compounds / Q000737:chemistry*
D001881:Borates; D017611:Fluorine Compounds; D017680:Potassium Compounds; D019800:Phenol; D002244:Carbon; D009532:Nickel; D010100:Oxygen