title: F-18 FDG PET/CT findings in pulmonary necrotizing sarcoid granulomatosis.
abstract: Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease that was described by Liebow in 1973. Dyspnea and chest pain may be present, as in our first patient; however, 25% of patients are asymptomatic, as our second patient. The typical radiographic findings are nonspecific: single or multiple lung opacities, with common involvement of the pleura. To the best of our knowledge, fluorodeoxyglucose (FDG) PET has only been reported in one case of NSG, which was atypical as it occurred in an adolescent. We report 2 cases, confirming that the lesions of NSG are FDG positive, showing a typical pattern of multiple bilateral lung nodules (imaged with PET/CT in 1 case). FDG imaging has a potential role when this distribution is observed on CT, to guide the surgical biopsy and show the actual extent of the disease.
authors: Department of Nuclear Medicine, Hôpital Tenon, Université Pierre et Marie Curie, Paris, France.
authors: Julia
authors: J
authors: Arfi
authors: Khaldoun
authors: K
authors: Kerrou
authors: Samba
authors: S
authors: Traore
authors: Virginie
authors: V
authors: Huchet
authors: Antoine
authors: A
authors: Bolly
authors: Martine
authors: M
authors: Antoine
authors: Luc
authors: L
authors: Delaunois
authors: Thierry
authors: T
authors: Vander Borght
authors: Jean-Noël
authors: JN
authors: Talbot
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D049268:Positron-Emission Tomography; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D019788:Fluorodeoxyglucose F18