title: Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]- derivatives.
abstract: CO plays an important role in biological processes and molecules which release CO in a controllable way could therefore be used for medicinal purposes. Beside organometallic carbonyl complexes, boranocarbonate [H(3)BCO(2)H](-) is one of the most promising candidates but releases CO too rapidly. In order to delay the CO release, we have prepared boranocarbamates [H(3)BCONH-R](-) from [H(3)BCO(2)H](-) which comprise histamine, morpholine, aniline and ethylene-diamine bound via amides to the {H(3)BCO} moiety. The syntheses of the new derivatives is described together with their structural characterization. These compounds release CO at a much slower rate than the parent compound and are therefore potential CO releasing molecules for biological and medicinal application.
authors: University of Zürich, Institute of Inorganic Chemistry, Winterthurerstr. 190, 8057, Zürich, Switzerland.
authors: Tamil Selvi
authors: TS
authors: Pitchumony
authors: Bernhard
authors: B
authors: Spingler
authors: Roberto
authors: R
authors: Motterlini
authors: Roger
authors: R
authors: Alberto
mesh_terms: D001880:Boranes / Q000138:chemical synthesis / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry*; D002254:Carbonates / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D001880:Boranes; D002254:Carbonates; C503854:sodium boranocarbonate; D002248:Carbon Monoxide