[Observation of Erlotinib in the Treatment of Elderly Patients with Advanced Non-small Cell Lung Cancer and COPD.].
BACKGROUND
To evaluate the clinical efficacy and the security of erlotinib in the treatment of elderly patients with advanced non-small cell lung cancer and COPD.


METHODS
Fifteen patients with advanced non-small cell lung cancer and COPD were treated with erlotinib 150 mg/d, and then the adverse reactions and clinical effects were recorded.


RESULTS
The effective rate was 20%. We analyzed the effective rate of stage III and IV, and there were no significant difference between the two (P=0.569). KPS was increased in 40% patients. Mild or moderate rash, diarrhea, nausea and vomiting were the main adverse reactions.


CONCLUSIONS
For elderly patients with advanced non-small cell lung cancer and COPD, the use of erlotinib might achieve better security and effectiveness.
Ma
Qing
Q
Department of Oncology, Tianjin Medical University General Hospital, Tianjin 300052, China. zzq_9@sina.com.
Ma
Li
L
Wang
Yan
Y
Meng
Fanlu
F
Zou
Linglin
L
Zhang
Huiling
H