title: Radiofrequency ablation for selective reduction in complex monochorionic pregnancies.
abstract: Monochorionic pregnancies present unique challenges for selective fetal reduction, as vaso-occlusive procedures are required to ablate blood flow, usually in the umbilical cord, to achieve asystole in the selected fetus. We describe a case series of 35 monochorionic pregnancies (27 twins and eight triplets) undergoing selective fetal reduction using radiofrequency ablation. All procedures were performed under local anaesthesia. The procedure was technically successful in all cases. The live born rate was 88.6%. One (2.9%) woman miscarried within 2 weeks of the procedure, and two (5.7%) babies were stillborn. The median gestation at delivery was 36 weeks of gestation (range 24-41 weeks). There were no maternal complications. The median gestational age at procedure was 17 + 3 weeks (range from 12 + 5 to 27 + 4 weeks). All women had antenatal magnetic resonance imaging (MRI) post procedure. There were two (5.7%) cases of abnormal brain imaging. Our experience suggests that radiofrequency ablation is a safe and effective procedure for fetal reduction in complicated monochorionic pregnancies.
authors: Centre for Fetal and Maternal Medicine, Queen Charlottes and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.
authors: G
authors: G
authors: Paramasivam
authors: R
authors: R
authors: Wimalasundera
authors: M
authors: M
authors: Wiechec
authors: E
authors: E
authors: Zhang
authors: F
authors: F
authors: Saeed
authors: S
authors: S
authors: Kumar
mesh_terms: D000328:Adult; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D005315:Fetal Diseases / Q000601:surgery; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology; D005333:Fetus / Q000002:abnormalities; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D018607:Pregnancy Reduction, Multifetal / Q000379:methods*; D011272:Pregnancy, Multiple; D011295:Prenatal Care / Q000379:methods; D014310:Triplets; D014430:Twins, Monozygotic; D055815:Young Adult