[Evaluation of the status of experimental animals after chronic sulfur steam inhalation].
Bronchoalveolar lavage (BAL) and the hepatorenal system were studied on albino rats in one-month regeneration period after 4-month chronic sulfur vapor in a dose of 1.76 and 12.68 microg/m3. Cytomorphological studies were used to detect the cumulative properties of sulfur: there were pathological processes in the hepatocytes; the light hepatocytes showed small-canalicular adipose degeneration, reduced dark cells, and increased degenerated light cells. There was a rise in the count of neutrophilic leukocytes, suggesting the progression of an inflammatory process in the regeneration period. The secretory function of the renal tubules exhibited destructive changes in the small and large light tubular cells; protein dystrophy was to a greater extent encountered in small tubular cells in the regeneration period.
Bazeliuk
L T
LT
Iskakova
S A
SA
D000818:Animals; D018893:Bronchoalveolar Lavage; D022781:Hepatocytes / Q000187:drug effects* / Q000473:pathology; D001239:Inhalation; D007668:Kidney / Q000187:drug effects* / Q000502:physiology; D007684:Kidney Tubules / Q000187:drug effects / Q000502:physiology; D008099:Liver / Q000187:drug effects* / Q000502:physiology; D009504:Neutrophils / Q000187:drug effects; D051381:Rats; D012038:Regeneration; D013227:Steam; D013455:Sulfur / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors
D013227:Steam; D013455:Sulfur