title: Schistosoma mansoni: magnetic resonance analysis of liver fibrosis according to WHO patterns for ultrasound assessment of schistosomiasis-related morbidity.
abstract: For the last two decades, ultrasound (US) has been considered a surrogate for the gold standard in the evaluation of liver fibrosis in schistosomiasis. The use of magnetic resonance imaging (MRI) is not yet standardised for diagnosing and grading liver schistosomal fibrosis. The aim of this paper was to analyse MRI using an adaptation of World Health Organization (WHO) patterns for US assessment of schistosomiasis-related morbidity. US and MRI were independently performed in 60 patients (42.1 +/- 13.4 years old), including 37 men and 23 women with schistosomiasis. Liver involvement appraised by US and MRI was classified according to the WHO protocol from patterns A-F. Agreement between image methods was evaluated by kappa index (k). The correlation between US and MRI was poor using WHO patterns [k = 0.14; confidence interval (CI) 0.02; 0.26]. Even after grouping image patterns as "A-D", "Dc-E" and "Ec-F", the correlation between US and MRI remained weak (k = 0.39; CI 0.21; 0.58). The magnetic resonance adaptation used in our study did not confirm US classification of WHO patterns for liver fibrosis.
authors: Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil. silva.luciana@ig.com.br
authors: Luciana C S
authors: LC
authors: Silva
authors: Luciene M
authors: LM
authors: Andrade
authors: Leonardo C de
authors: LC
authors: Queiroz
authors: Izabela
authors: I
authors: Voieta
authors: Letícia M
authors: LM
authors: Azeredo
authors: Carlos M F
authors: CM
authors: Antunes
authors: José R
authors: JR
authors: Lambertucci
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging* / Q000469:parasitology / Q000473:pathology*; D008109:Liver Diseases, Parasitic / Q000000981:diagnostic imaging* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012555:Schistosomiasis mansoni / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D012720:Severity of Illness Index; D014463:Ultrasonography; D014944:World Health Organization; D055815:Young Adult