title: [Maternal and obstetrical data in a retrospective cohort of 170 newborns from polydrug using mothers, in the Paris area, 1999-2008].
abstract: OBJECTIVE
  Polydrug use in pregnancy is harmful. This survey aimed to explore the issue of the associations of substances during pregnancy and to determine the consumer profiles.
  
  
  METHODS
  One hundred and seventy newborns whose mothers were psychoactive substances users were identified over the period 1999 to 2008. The data relating to maternal consumption, their reproductive history, and their living environment were collated.
  
  
  RESULTS
  At the end of their pregnancy, the mothers reported using on average 3.14 substances. Three profiles were determined: 65 women were heroin users or had consumed it in their lifetime and were currently on substitution treatment, and had a very unfavourable social living environment; 30 women were mainly consumers of alcohol, with or without benzodiazepines or other psychotropic drugs, and had a history of abortions; 75 women were mainly tobacco and cannabis smokers, with or without substitution treatment, had good social living conditions and had wanted the pregnancy.
  
  
  CONCLUSIONS
  Polydrug use increases the risk for the women to avoid prenatal care and is often linked with a history of abortions.
authors: CERMES3, CNRS-EHESS, UMR 8211, Inserm U988, université Paris Descartes, 45, rue des Saints-Pères, 75270 Paris cedex 06, France. Laurence.simmat-durand@parisdescartes.fr
authors: L
authors: L
authors: Simmat-Durand
authors: S
authors: S
authors: Toutain
authors: N
authors: N
authors: Vellut
authors: L
authors: L
authors: Genest
authors: C
authors: C
authors: Crenn-Hebert
authors: A-M
authors: AM
authors: Simonpoli
authors: E
authors: E
authors: Miossec
authors: C
authors: C
authors: Lejeune
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data; D019970:Cocaine-Related Disorders / Q000150:complications; D015331:Cohort Studies; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D006556:Heroin Dependence / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D008385:Marijuana Smoking / Q000009:adverse effects; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011619:Psychotropic Drugs / Q000008:administration & dosage / Q000009:adverse effects; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D011619:Psychotropic Drugs; D000431:Ethanol; D018817:N-Methyl-3,4-methylenedioxyamphetamine