title: Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst.
abstract: A novel fluorous (S)-pyrrolidine-thiourea bifunctional organocatalyst is prepared. The catalyst shows good activity and enantioselectivity for direct α-chlorination of aldehydes using N-chlorosuccinimide (NCS) as the chlorine source. It can be recovered from the reaction mixture by fluorous solid-phase extraction with excellent purity for direct reuse.
authors: Chemical Engineering College, Nanjing University of Science & Technology, Nanjing 210094, P. R. China.
authors: Liang
authors: L
authors: Wang
authors: Chun
authors: C
authors: Cai
authors: Dennis P
authors: DP
authors: Curran
authors: Wei
authors: W
authors: Zhang