Neuroscience. A glutamate pathway to faster-acting antidepressants?
Cryan
John F
JF
School of Pharmacy, Department of Pharmacology and Therapeutics, Alimentary Pharmabiotic Centre, University College Cork, College Road, Cork, Ireland. j.cryan@ucc.ie
O'Leary
Olivia F
OF
D000818:Animals; D000928:Antidepressive Agents / Q000493:pharmacokinetics*; D004357:Drug Synergism; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D007649:Ketamine / Q000494:pharmacology* / Q000627:therapeutic use; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D051381:Rats; D020123:Sirolimus / Q000494:pharmacology; D009435:Synaptic Transmission / Q000187:drug effects; D058570:TOR Serine-Threonine Kinases
D000928:Antidepressive Agents; D018691:Excitatory Amino Acid Antagonists; D047908:Intracellular Signaling Peptides and Proteins; D007649:Ketamine; C546842:MTOR protein, human; D017346:Protein Serine-Threonine Kinases; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus