A study of heating duration and scanning path in focused ultrasound surgery.
A conventional method of avoiding normal tissue overheating during focused ultrasound surgery (FUS) is to apply equal heating duration for each sonication in between cooling intervals. However, this method is time-consuming and expensive. A novel method with unequal heating duration in different scanning paths without cooling intervals was investigated in this paper. This method was compared with the conventional method through the ablation of a 10 × 10 cm(2) target. The simulation results indicated that the new method was able to reduce treatment time by more than 50%, with higher than 95% coverage index, and more uniform thermal dose distribution. The method was further verified through the ablation of a circular lesion. Ex vivo experiments were also performed to confirm the simulation results. Both simulation and experimental results have proven that the new method can increase heating efficiency, and are a promising new approach in FUS.
Li
Dehui
D
Biomedical Instrument Institute, Shanghai Jiao Tong University, Shanghai, China.
Shen
Guofeng
G
Luo
Hui
H
Bai
Jingfeng
J
Bai
Jinfeng
J
Chen
Yazhu
Y
D055011:Ablation Techniques / Q000379:methods; D000818:Animals; D003198:Computer Simulation; D006358:Hot Temperature; D018482:Muscle, Skeletal / Q000528:radiation effects; D013552:Swine; D013997:Time Factors; D059708:Ultrasonic Surgical Procedures / Q000379:methods*