Efficient sonochemical synthesis of thiazolidinones from piperonilamine.
An efficient multicomponent reaction of arenealdehydes, mercaptoacetic acid and piperonilamine under ultrasound irradiation to afford 2-aryl-3-(piperonylmethyl)-1,3-thiazolidin-4-ones is reported. Applying this methodology, eleven heterocycles were synthesized and isolated in good yields after short reaction times.
Neuenfeldt
Patrícia D
PD
Núcleo de Química Aplicada (NuQuiA), Departamento de Química Orgânica, Universidade Federal de Pelotas-UFPel, Campus Universitário s/no, 96010-900 Pelotas, RS, Brazil.
Duval
Auri R
AR
Drawanz
Bruna B
BB
Rosales
Pauline F
PF
Gomes
Claudia R B
CR
Pereira
Claudio M P
CM
Cunico
Wilson
W
D052117:Benzodioxoles / Q000737:chemistry*; D003500:Cyclization; D055664:Electrochemical Techniques; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008744:Methylamines / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D053778:Thiazolidines / Q000138:chemical synthesis* / Q000737:chemistry; D014465:Ultrasonics
D052117:Benzodioxoles; D006571:Heterocyclic Compounds; D008744:Methylamines; D053778:Thiazolidines; C554928:piperonilamine