Thrombotic thrombocytopenic purpura: A single - Centre experience.
We aimed to describe the characteristics, treatment regime, and 6-month all-cause mortality of thrombotic thrombocytopenic purpura (TTP) patients treated with total plasma exchange in the our clinic. Thirteen patients were included in the study. Mortality rates of TTP have improved over the last three decades but they are still too high according to modern therapy expectations. Etiology directed treatment should be added to total plasma exchange in secondary TTP cases. Based on TTPs' immunologic etiology, immune modulator and immune suppressor agents have been applied together with total plasma exchange, but mostly in anecdotal case reports or with questionable responses.
Yildirim
Rahsan
R
Department of Hematology, Ataturk University, School of Medicine, Erzurum, Turkey. rahsan.yildiri@hotmail.com
Bilen
Yusuf
Y
Keles
Mustafa
M
Uyanik
Abdullah
A
Albayrak
Fatih
F
Erdem
Fuat
F
Kiki
Ilhami
I
Cetinkaya
Ramazan
R
Gundogdu
Mehmet
M
D000328:Adult; D000368:Aged; D005260:Female; D006454:Hemoglobins / Q000737:chemistry; D006801:Humans; D007107:Immune System; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange / Q000379:methods*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors
D006454:Hemoglobins