The efficient synthesis of isotopically labeled peptide-derived Amadori products and their characterization.
Protein glycation is often a cause of diabetes-associated complications. The isotopically labeled peptide-derived Amadori products may serve as standards for quantitative determination of the glycated proteins. In this paper, we discussed various approaches to the synthesis of Amadori products labeled selectively with stable isotopes (2)H, (13)C and (18)O.
Kapczyńska
Katarzyna
K
Faculty of Chemistry, University of Wrocław, F. Joliot-Curie 14, Wroclaw, Poland.
Stefanowicz
Piotr
P
Jaremko
Lukasz
L
Jaremko
Mariusz
M
Kluczyk
Alicja
A
Szewczuk
Zbigniew
Z
D006031:Glycosylation; D007553:Isotope Labeling; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*
D010455:Peptides