title: Organocatalytic synthesis of spiro compounds via a cascade Michael-Michael-aldol reaction.
abstract: The synthesis of spiro compounds via a Michael-Michael-aldol reaction is reported. The reaction affords spirooxindole derivatives in good yields and in almost diastereo- and enantiopure form. Moreover, the reaction works with several heterocycles such as oxindoles, benzofuranones, pyrazolones or azlactones rendering the final spiro compounds in good yields and excellent stereoselectivities.
authors: Department de Química Orgànica, Universitat de Barcelona, Martí i Franqués 1-11, 08028 Barcelona, Spain.
authors: Xavier
authors: X
authors: Companyó
authors: Alex
authors: A
authors: Zea
authors: Andrea-Nekane R
authors: AN
authors: Alba
authors: Andrea
authors: A
authors: Mazzanti
authors: Albert
authors: A
authors: Moyano
authors: Ramon
authors: R
authors: Rios
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D013141:Spiro Compounds