Gastric plexiform angiomyxoid myofibroblastic tumor.
Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a relatively recently described gastric tumor with a peculiar plexiform growth pattern. PAMT is typified by a myofibroblastic immunophenotype that distinguishes it from the more common gastrointestinal stromal tumors and the rarely documented fibromyxomas. We report an additional PAMT, the seventh tumor with this label, which was an incidental finding on abdominal computed tomography scan of a 35-year-old Indian female. The tumor measured 4 x 3 x 2 cm and demonstrated plexiform architecture, myxoid stroma, prominent vasculature and spindled cells with myofibroblastic differentiation. The clinicopathological features, progesterone immunopositivity, hitherto undocumented, and mimicry of other primary and secondary gastric mesenchymal tumors, including endometrial stromal sarcoma, are discussed.
Sing
Yetish
Y
Department of Anatomical Pathology, University of KwaZulu Natal, Durban, KwaZulu Natal, South Africa. singy@ukzn.ac.za
Subrayan
Sumeshini
S
Mqadi
Buhle
B
Ramdial
Pratistadevi K
PK
Reddy
Jenendhiran
J
Moodley
Manogran S
MS
Bux
Shamim
S
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000175:diagnosis / Q000473:pathology; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis* / Q000473:pathology*; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology*