title: Survival to akinetic mutism state in Japanese cases of MM1-type sporadic Creutzfeldt-Jakob disease is similar to Caucasians.
abstract: BACKGROUND
  It is not known whether the clinical course of Japanese sporadic Creutzfeldt-Jakob disease (sCJD) cases differs from that of Caucasian sCJD cases.
  
  
  METHODS
  To investigate the clinical course of Japanese sCJD, clinical findings from 29 patients with Japanese MM1-type sCJD were retrospectively evaluated and compared to Caucasian sCJD findings.
  
  
  RESULTS
  Survival of Japanese MM1-type sCJD up to the time of akinetic mutism state is similar to that of Caucasian subjects. However, the total disease duration of Japanese patients was approximately three times longer.
  
  
  CONCLUSIONS
  The present observations indicate that Japanese sCJD cases generally show a longer disease duration because of the longer survival period after reaching the akinetic mutism state.
authors: Department of Neurology, Oyamada Memorial Spa Hospital, Yokkaichi, Japan. iwasaki@sc4.so-net.ne.jp
authors: Y
authors: Y
authors: Iwasaki
authors: M
authors: M
authors: Mimuro
authors: M
authors: M
authors: Yoshida
authors: T
authors: T
authors: Kitamoto
authors: Y
authors: Y
authors: Hashizume
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000405:Akinetic Mutism / Q000208:ethnology* / Q000209:etiology*; D044466:Asian People; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000208:ethnology* / Q000401:mortality; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013995:Time; D044465:White People