title: Challenges in clinical-pathologic correlations: acute tubular necrosis in a patient with collapsing focal and segmental glomerulosclerosis mimicking rapidly progressive glomerulonephritis.
abstract: Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated pulse therapy with methylprednisolone and cyclophosphamide. The case presentation is followed by a brief overview of the epidemiology of AKI in nephrotic syndrome as well as a discussion of its risk factors and potential mechanisms involved.
authors: Departamento de Medicina, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Bahia, Brazil.
authors: Mariana Freire
authors: MF
authors: Rodamilans
authors: Luisa Leite
authors: LL
authors: Barros
authors: Marcia M
authors: MM
authors: Carneiro
authors: Washington Luis Conrado
authors: WL
authors: dos Santos
authors: Paulo Novis
authors: PN
authors: Rocha
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D007683:Kidney Tubular Necrosis, Acute / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D008875:Middle Aged