False-positive MIBG uptake in pneumonia in a patient with stage IV neuroblastoma.
A 32-month-old female child with a history of stage IV favorable biology neuroblastoma with a 123-I MIBG (metaiodobenzylguanidine scan) avid adrenal mass, with retroperitoneal nodal extension and bony metastasis, was in complete remission after intense multimodal therapy. Seventeen months after diagnosis a surveillance 123-I MIBG scan showed abnormal tracer uptake in the midzone of the right thorax. Chest x-ray and CT scan confirmed right upper lobe consolidation corresponding to the tracer uptake. Chest x-ray after antibiotics showed resolution of the abnormality. 123-I MIBG scan 3 months later showed no abnormal uptake. False-positive MIBG uptake in pneumonia has not been previously reported.
Schindler
Tim
T
Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick, NSW, Australia.
Yu
Chris
C
Rossleigh
Monica
M
Pereira
John
J
Cohn
Richard
R
D019797:3-Iodobenzylguanidine / Q000493:pharmacokinetics*; D002675:Child, Preschool; D005189:False Positive Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000150:complications* / Q000000981:diagnostic imaging* / Q000473:pathology; D011014:Pneumonia / Q000150:complications* / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed
D019797:3-Iodobenzylguanidine