title: Malignancies in pediatric solid organ transplant recipients: epidemiology, risk factors, and prophylactic approaches.
abstract: OBJECTIVE
  To review current opinions about the epidemiology, risk factors, and approaches to prevent malignancies in pediatric transplant recipients.
  
  
  RESULTS
  Recent studies looking at the risk of newer induction agents and viral etiologies are reviewed. The recent introduction of viral immunizations as prophylaxis is also discussed.
  
  
  CONCLUSIONS
  Children remain one of the most vulnerable populations for developing cancer posttransplant. This is because of multiple variables, but especially because of immune naivete and longer periods of immunosuppression. As transplantation gets more complex, with discovery of newer immunosuppressive agents and viral agents, all of these affect the incidence of malignancy in the posttransplant period. A review of the latest literature in this aspect with data from the largest current transplant databases is herein presented.
authors: Tulane Abdominal Transplant Institute, Department of Surgery, Tulane University, New Orleans, Louisiana 70112, USA.
authors: Anil
authors: A
authors: Paramesh
authors: Robert
authors: R
authors: Cannon
authors: Joseph F
authors: JF
authors: Buell
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D009369:Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D016377:Organ Transplantation / Q000009:adverse effects*; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D014765:Viral Vaccines; D014777:Virus Diseases / Q000209:etiology / Q000517:prevention & control
chemical_list: D007166:Immunosuppressive Agents; D014765:Viral Vaccines