Biosynthesis, metabolism, molecular engineering, and biological functions of stilbene phytoalexins in plants.
Stilbenic compounds recently have become the focus of a number of studies in medicine and plant physiology as well as have emerged as promising molecules that potentially affect human health. Stilbenes are relatively simple compounds synthesized by plants and deriving from the phenyalanine/polymalonate route, the last and key enzyme of this pathway being stilbene synthase. Here, we review the biological significance of stilbenes in plants together with their biosynthesis pathway and their metabolism both by fungi and in planta. Special attention will be paid to the role of stilbenic molecules as phytoalexins.
Jeandet
Philippe
P
UPRES EA, University of Reims, France. philippe.jeandet@univ-reims.fr
Delaunois
Bertrand
B
Conreux
Alexandra
A
Donnez
David
D
Nuzzo
Vitale
V
Cordelier
Sylvain
S
Clément
Christophe
C
Courot
Eric
E
D018528:ATP-Binding Cassette Transporters / Q000502:physiology; D000217:Acyltransferases / Q000378:metabolism; D000935:Antifungal Agents / Q000494:pharmacology; D005658:Fungi / Q000472:pathogenicity; D005818:Genetic Engineering; D010944:Plants / Q000378:metabolism*; D000077185:Resveratrol; D012717:Sesquiterpenes / Q000378:metabolism* / Q000494:pharmacology; D013267:Stilbenes / Q000378:metabolism*; D000094162:Phytoalexins
D018528:ATP-Binding Cassette Transporters; D000935:Antifungal Agents; D012717:Sesquiterpenes; D013267:Stilbenes; D000217:Acyltransferases; C022674:stilbene synthase; D000077185:Resveratrol; D000094162:Phytoalexins