Neurobrucellosis associated with syndrome of inappropriate antidiuretic hormone with resultant diabetes insipidus and hypothyroidism.
Neurological involvement of the central nervous system in brucellosis is uncommon. We describe a rare case of meningoencephalitis due to Brucella melitensis infection, associated with the syndrome of inappropriate antidiuretic hormone secretion and leading to diabetes insipidus and hypothyroidism. Neurobrucellosis, although rare, should be considered in cases of neurological disease of unknown etiology.
Sturniolo
Giuseppe
G
Department of Infectious Diseases, G. Martino Hospital, University of Messina, Messina, Italy.
Mondello
Placido
P
Bruno
Salvatore
S
Bonfatto
Orsola Elena
OE
Frattima
Sabrina
S
Albanese
Antonio
A
Restivo
Roberta
R
Liberti
Giuseppe
G
Pasquali
Paolo
P
Marianelli
Cinzia
C
D000293:Adolescent; D017347:Brucella melitensis / Q000302:isolation & purification*; D002006:Brucellosis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D003919:Diabetes Insipidus / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008590:Meningoencephalitis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D014667:Vasopressins / Q000378:metabolism
D014667:Vasopressins