title: Short-term repeatability of diurnal intraocular pressure patterns in glaucomatous individuals.
abstract: OBJECTIVE
  To evaluate the short-term repeatability of diurnal intraocular pressure (IOP) patterns in eyes with primary open-angle glaucoma (POAG).
  
  
  METHODS
  Observational cohort study.
  
  
  METHODS
  Forty-seven subjects with treated POAG.
  
  
  METHODS
  Subjects underwent assessment of IOP using Goldmann tonometry every 2 hours from 0800 to 2000 on 2 visits 1 week apart. Intervisit agreement of IOP by time point and of IOP change between time points was assessed using intraclass correlation coefficients (ICCs).
  
  
  METHODS
  Diurnal IOP patterns.
  
  
  RESULTS
  Between-visit agreement of IOP values at each time point was generally fair to good, with ICCs ranging from 0.45 to 0.71 in right eyes and from 0.51 to 0.71 in left eyes. Between-visit agreement of IOP change over time periods between time points was uniformly poor, with ICCs ranging from -0.08 to 0.38 in right eyes and from -0.11 to 0.36 in left eyes.
  
  
  CONCLUSIONS
  Treated POAG patients do not manifest a repeatable diurnal IOP pattern from day to day when measured by Goldmann tonometry. Measurement of single-day IOP variation poorly characterized short-term IOP variation.
authors: Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, USA.
authors: Tony
authors: T
authors: Realini
authors: Robert N
authors: RN
authors: Weinreb
authors: N
authors: N
authors: Weinreb
authors: Stephen
authors: S
authors: Wisniewski
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002940:Circadian Rhythm / Q000502:physiology*; D015331:Cohort Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D011446:Prospective Studies; D015203:Reproducibility of Results; D014065:Tonometry, Ocular
chemical_list: D000959:Antihypertensive Agents