title: Well-defined and easily accessible yttrium complexes for enantioselective cyclisation of amines tethered to 1,2-di-substituted alkenes.
abstract: A straightforward in situ preparation of new chiral amido alkyl ate yttrium complexes is described. They catalysed the enantioselective cyclisation of 1,2-dialkyl-substituted aminopentenes in up to 77% ee, a significant value for this challenging transformation. Complex [(R)-L(0)][Y(CH(2)TMS)(2).Li(THF)(4)] undergoes C-H bond activation resulting in the formation of an original dimeric heterobimetallic yttrium complex which also acts as an active precatalyst.
authors: Univ. Paris-Sud, Equipe de Catalyse Moléculaire, ICMMO, UMR 8182, Orsay, F-91405, France.
authors: Yulia
authors: Y
authors: Chapurina
authors: Jérôme
authors: J
authors: Hannedouche
authors: Jacqueline
authors: J
authors: Collin
authors: Régis
authors: R
authors: Guillot
authors: Emmanuelle
authors: E
authors: Schulz
authors: Alexander
authors: A
authors: Trifonov
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism; D015019:Yttrium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000588:Amines; D009942:Organometallic Compounds; D015019:Yttrium