Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases.
NAD 2D NMR spectroscopy using chiral mesophases made of poly-gamma-benzyl-l-glutamate and pyridine allowed us to evaluate, for the first time, the natural site-specific enantio-isotopomeric excesses at each methylene group of linoleic acid, a central, essential PUFA precursor of all conjugated triene fatty acids.
Serhan
Zeinab
Z
Université de Paris Sud 11, RMN en Milieu Orienté, ICMMO, UMR CNRS 8182, Bât. 410, F-91405 Orsay, France.
Martel
Laura
L
Billault
Isabelle
I
Lesot
Philippe
P
D003903:Deuterium / Q000737:chemistry; D019787:Linoleic Acid / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010455:Peptides / Q000737:chemistry*; D011099:Polyglutamic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry; D013237:Stereoisomerism
D010455:Peptides; D011725:Pyridines; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; D019787:Linoleic Acid; D003903:Deuterium; C023666:pyridine