title: Implementing a program to improve compliance with neonatal intensive care unit transfusion guidelines was accompanied by a reduction in transfusion rate: a pre-post analysis within a multihospital health care system.
abstract: BACKGROUND
  We previously reported that in the year 2006, approximately 35% of the transfusions administered in the Intermountain Healthcare neonatal intensive care units (NICU) were noncompliant with our transfusion guidelines. In January 2009 we instituted an electronic NICU transfusion ordering and monitoring system as part of a new program to improve compliance with transfusion guidelines.
  
  
  METHODS
  In the four largest NICUs of Intermountain Healthcare, we performed a pre-post analysis of compliance with transfusion guidelines and transfusion usage.
  
  
  RESULTS
  After beginning the new transfusion compliance program all four NICUs had an increase in compliance from 65% to 90%. Accompanying the improved compliance, all four NICUs had a reduction in transfusions administered. Specifically, compared with 2007 and 2008, there were 984 fewer NICU transfusions given in 2009. This included 554 fewer red blood cell (RBC) transfusions, 174 fewer platelet transfusions, and 256 fewer frozen plasma infusions. We calculate that in 2009, a total of 200 NICU patients who in previous years would have received one or more transfusions instead received none. Applying specific Intermountain Healthcare billing data to the observed transfusion reductions, this new program resulted in an annual decrease of $780,074 in blood bank charges (blood administration charges were not included). During the 3-year period, January 2007 through December 2009, we detected no change in NICU demographics, major morbidities, length of hospital stay, or mortality rate.
  
  
  CONCLUSIONS
  Implementing a systemwide NICU program to improve compliance with already-established transfusion guidelines increased compliance from 65% to 90%. Improved compliance with transfusion guidelines was accompanied by a significant reduction in transfusions given, with no increase in NICU length of stay or mortality rate.
authors: Women and Newborn's Clinical Program, Intermountain Healthcare, Salt Lake City, Utah 84403, USA.
authors: Vickie L
authors: VL
authors: Baer
authors: Erick
authors: E
authors: Henry
authors: Diane K
authors: DK
authors: Lambert
authors: Ronald A
authors: RA
authors: Stoddard
authors: Susan E
authors: SE
authors: Wiedmeier
authors: Larry D
authors: LD
authors: Eggert
authors: Sarah
authors: S
authors: Ilstrup
authors: Robert D
authors: RD
authors: Christensen
mesh_terms: D001724:Birth Weight; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D002543:Cerebral Hemorrhage / Q000453:epidemiology; D057286:Electronic Health Records / Q000706:statistics & numerical data; D020345:Enterocolitis, Necrotizing / Q000453:epidemiology; D015199:Extracorporeal Membrane Oxygenation; D005865:Gestational Age; D019983:Guideline Adherence / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D015931:Intensive Care, Neonatal / Q000379:methods* / Q000706:statistics & numerical data; D007902:Length of Stay; D009096:Multi-Institutional Systems / Q000706:statistics & numerical data*; D017410:Practice Guidelines as Topic; D015397:Program Evaluation; D019564:Unnecessary Procedures; D014589:Utah / Q000453:epidemiology