Poor positive accuracy of QuickVue rapid antigen tests during the influenza A (H1N1) 2009 pandemic.
We assessed the accuracy of positive QuickVue rapid influenza virus antigen test results. Using reverse transcription (RT)-PCR as the gold standard, 17 (37.8%) of 45 QuickVue-positive specimens were determined to be false positives. We report an unexpectedly high rate of false-positive QuickVue results during a period of high influenza A (H1N1) 2009 virus prevalence.
Stevenson
Heather L
HL
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0740, USA.
Loeffelholz
Michael J
MJ
D000293:Adolescent; D000956:Antigens, Viral / Q000032:analysis*; D002648:Child; D005189:False Positive Reactions; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology*; D011933:Reagent Kits, Diagnostic; D055815:Young Adult
D000956:Antigens, Viral; D011933:Reagent Kits, Diagnostic