title: [Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides].
abstract: OBJECTIVE
  To investigate the chemical constituents from the whole plants of Senecio chrysanthemoides.
  
  
  METHODS
  The chemical constituents were isolated and purified by chromatographic techniques over silica gel, Sephadex LH-20, preparative TLC and preparative HPLC. Structures of the compounds were identified by NMR and MS spectroscopic methods.
  
  
  RESULTS
  Twenty five compounds were obtained and their structures were elucidated as seneciphyline (1), senecionine (2) , 1,2-dihydrocacalohastine (3) , eu-desm-4( 15)-ene-1beta,6alpha-diol (4), 7,11,15-trimethyl- 3methylidenehexadecane-1,2-diol (5), faradiol 3-O-palmitate (6),maniladiol 3-O-palmitate (7), faradiol (8), maniladiol (9), beta-amyrin (10), alpha-amyrin (11), betulin (12), loranthol (13), (+)-syringaresinol (14) , 1-hydroxy-4-oxo-cyclohexane-1-acetate (15), 2, 6-dimethoxy-p-benzoquinone (16), stigmasta-5, 22-dien-3beta-hydroxy-7-one (17) , stigmasta-5, 22-dien-7-one (18) , stigmasta-4-en-3-one (19), stigmasta-4,22-dien-3-one (20), beta-sitosterol (21), stigmasterol (22), daucosterol (23), glycerol 1-hendecanoate (24), and methyl hendecanoate (25).
  
  
  CONCLUSIONS
  Compounds 5-9,13, 17-20 and 24 were obtained from the genus Senecio for the first time.
authors: College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
authors: Sheng
authors: S
authors: Lin
authors: Zhongxiao
authors: Z
authors: Zhanf
authors: Yunheng
authors: Y
authors: Shen
authors: Huiliang
authors: H
authors: Li
authors: Lei
authors: L
authors: Shan
authors: Runhui
authors: R
authors: Liu
authors: Xike
authors: X
authors: Xu
authors: Weidong
authors: W
authors: Zhanf
mesh_terms: D000085:Acetates / Q000737:chemistry; D005591:Chemical Fractionation; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification; D012674:Senecio / Q000737:chemistry*
chemical_list: D000085:Acetates; D010936:Plant Extracts