Benign childhood epilepsy with centro-temporal spikes: evolutive clinical, cognitive and EEG aspects.
Thirty-two children with benign childhood epilepsy with centrotemporal spikes (BECTS) were studied for a mean period of 27.6 months. The characteristics of the seizures, electroencephalogram (EEG), WISC-III and School Performance Test were compared at the start and end of the study. Nine (28.1%) children continued having seizures. Epileptiform activity (EA) on the EEG reduced in number and was no longer recorded in 6 (18.7%) children. There was a significant improvement in the performance and perceptual organization IQ values. The improvement in reading performance failed to reach statistical significance. The performance in arithmetic worsened in 43.7% of the children, and this was associated with the persistence of epileptic seizures. There were no significant correlations between changes in cognitive aspects and characteristics of EA. There is a need to continue this study, and also search for other factors influencing the evolution of cognitive abilities in children with BECTS.
Tedrus
Glória M A S
GM
Pontifícia Universidade Católica de Campinas, Campinas, SP, Brazil. gmtedrus@uol.com.br
Fonseca
Lineu C
LC
Castilho
Dioraci P
DP
Pacheco
Elizabeth M C
EM
Campregher
Amanda A
AA
Bittar
Marina C
MC
D002648:Child; D003072:Cognition Disorders / Q000150:complications / Q000503:physiopathology*; D004569:Electroencephalography; D019305:Epilepsy, Rolandic / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology