A divergent synthesis of modular dendrimers via sequential C-C bond fragmentation thio-Michael addition.
The C-C bond fragmentation of carbocycles has been developed as a new method for the divergent synthesis of dendrimers. The scope of this reaction was examined with the preparation of six first generation dendrimers from structurally diverse and readily available fragmentation precursors. By pairing the fragmentation with a thio-Michael reaction, the preparation of a [G4]-ene(24) dendrimer has been achieved.
Hierold
Judith
J
Monash University, Clayton, Victoria 3800, Australia.
Gray-Weale
Angus
A
Lupton
David W
DW
D000475:Alkenes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation
D000475:Alkenes; D050091:Dendrimers; D002244:Carbon