Horseradish peroxidase-functionalized Pt hollow nanospheres and multiple redox probes as trace labels for a sensitive simultaneous multianalyte electrochemical immunoassay.
A novel strategy for a simultaneous multianalyte electrochemical immunoassay is proposed using thionine-labeled anti-AFP and ferrocene-labeled anti-CEA as tracers; each biorecognition event yielded a distinct voltammetric peak, whose position and size reflected the identify and level of the corresponding antigen.
Song
Zhongju
Z
Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
Yuan
Ruo
R
Chai
Yaqin
Y
Zhuo
Ying
Y
Jiang
Wen
W
Su
Huilan
H
Che
Xin
X
Li
Jingjing
J
D000906:Antibodies / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000276:immunology; D055664:Electrochemical Techniques; D005296:Ferrous Compounds / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry* / Q000378:metabolism; D007118:Immunoassay; D000075163:Metallocenes; D054118:Nanospheres / Q000737:chemistry*; D010084:Oxidation-Reduction; D010640:Phenothiazines / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*; D000509:alpha-Fetoproteins / Q000276:immunology
D000906:Antibodies; D002272:Carcinoembryonic Antigen; D005296:Ferrous Compounds; D000075163:Metallocenes; D010640:Phenothiazines; D000509:alpha-Fetoproteins; D010984:Platinum; D006735:Horseradish Peroxidase; C004998:ferrocene; C009469:thionine