title: Does a family history of male breast cancer influence risk perception and use of genetic testing?
abstract: We sought to determine differences in risk perception and use of genetic testing in these individuals compared with those with a family history of female breast cancer (FHxFBC) in a population-based cohort. Data from the 2005 National Health Interview Survey were used to assess risk perception and use of genetic counseling in individuals with a family history of male breast cancer (FHxMBC) versus those with a FHxFBC. Of the 2429 individuals with a first-degree relative with breast cancer surveyed, 21 (0.7%) had a FHxMBC, whereas 2408 (99.3%) had a FHxFBC. Women who had a FHxMBC perceived themselves as being at higher risk for developing breast cancer than those with a FHxFBC (61.5 vs 46.5%, P = 0.011). Fewer individuals with a FHxMBC had heard about genetic testing than those with a FHxFBC (38.4 vs 50.8%, P = 0.322). Of these, none of the individuals with a FHxMBC discussed this with their physician (vs 13% of individuals with a FHxFBC, P = 0.004) and none underwent genetic testing (vs 3% of individuals with a FHxFBC, P = 0.009). Women with a FHxMBC perceive this as being associated with increased cancer risk, but few discuss this with their physicians. Physicians should be proactive in discussing risk with these patients.
authors: Department of Surgery, University of Louisville, Louisville, Kentucky, USA.
authors: Suzanne C
authors: SC
authors: Schiffman
authors: Anees B
authors: AB
authors: Chagpar
mesh_terms: D001294:Attitude to Health; D018567:Breast Neoplasms, Male / Q000235:genetics* / Q000523:psychology*; D005260:Female; D005820:Genetic Testing; D006801:Humans; D008297:Male