Case series are no substitute for randomised placebo-controlled trials for determination of treatment efficacy.
Buchbinder
R
R
D016022:Case-Control Studies; D050815:Fractures, Compression / Q000209:etiology / Q000601:surgery*; D006801:Humans; D010024:Osteoporosis / Q000150:complications*; D010919:Placebos; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012107:Research Design; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery*; D013131:Spine / Q000601:surgery; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods*
D010919:Placebos