title: CT fluoroscopy-guided lung biopsy versus conventional CT-guided lung biopsy: a prospective controlled study to assess radiation doses and diagnostic performance.
abstract: OBJECTIVE
  We evaluated radiation doses, complication rates, and diagnostic accuracy for CT-guided percutaneous needle aspiration biopsy (NAB) procedures of pulmonary lesions performed with or without fluoroscopic guidance.
  
  
  METHODS
  A total of 142 patients were prospectively enrolled to receive CT-guided NAB with (Group I, n = 72) or without (Group II, n = 70) fluoroscopic guidance. Outcome measurements were patient and doctor radiation dose, and complication rate. Sensitivity, specificity and accuracy were calculated based on 123 NAB results.
  
  
  RESULTS
  The mean estimated effective patient radiation dose was 6.53 mSv in Group I and 2.72 mSv in Group II (p < 0.001). The mean estimated effective doctor dose was 0.054 mSv in Group I and 0.029 mSv in Group II (p < 0.001). The complication rate was significantly different between the two groups (13.4% versus 31.4%, p = 0.012). Sensitivity, specificity and accuracy for diagnosing pulmonary lesions were 97.8%, 100% and 98.4% in group I and 95.3%, 100% and 89.5% in group II (p > 0.05).
  
  
  CONCLUSIONS
  CT fluoroscopy-guided NAB of pulmonary lesions provides high diagnostic accuracy and can be performed with significantly fewer complications. However, radiation exposure to both patient and doctor were significantly higher than conventional CT-guided NAB.
authors: Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea.
authors: Ga Ram
authors: GR
authors: Kim
authors: Jin
authors: J
authors: Hur
authors: Sang Min
authors: SM
authors: Lee
authors: Hye-Jeong
authors: HJ
authors: Lee
authors: Yoo Jin
authors: YJ
authors: Hong
authors: Ji Eun
authors: JE
authors: Nam
authors: Hua Sun
authors: HS
authors: Kim
authors: Young Jin
authors: YJ
authors: Kim
authors: Byoung Wook
authors: BW
authors: Choi
authors: Tae Hoon
authors: TH
authors: Kim
authors: Kyu Ok
authors: KO
authors: Choe
mesh_terms: D001707:Biopsy, Needle / Q000706:statistics & numerical data*; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D011829:Radiation Dosage; D015641:Radiography, Interventional / Q000706:statistics & numerical data*; D011874:Radiometry / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*