A new HLA-B*15 variant, B*15:144, identified by sequence-based typing in a Chinese individual.
A novel human leukocyte antigen-B allele, officially named B*15:144 allele, the previous designation B*9544 allele, was found in a potential Chinese bone marrow donor when direct sequence-based typing was carried out. The novel B*15:144 is identical to B*15:02:01 with the exception of two base substitution at position 195 (C>T), 196 (T>G) of exon 3 resulting in codon #156 changed from CTG (Leu) to TGG (Trp).
Dong
L
L
Tissue Typing Lab, Tianjin Blood Center, Tianjin, China.
Yan
L-N
LN
Xie
J-H
JH
An
S-P
SP
Yuan
Y-H
YH
D000483:Alleles; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D002681:China; D004247:DNA / Q000235:genetics; D005091:Exons; D005805:Genes, MHC Class I; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D059910:HLA-B15 Antigen; D006801:Humans; D008969:Molecular Sequence Data
D015235:HLA-B Antigens; D059910:HLA-B15 Antigen; D004247:DNA