title: Biosynthesis, metabolism, molecular engineering, and biological functions of stilbene phytoalexins in plants.
abstract: Stilbenic compounds recently have become the focus of a number of studies in medicine and plant physiology as well as have emerged as promising molecules that potentially affect human health. Stilbenes are relatively simple compounds synthesized by plants and deriving from the phenyalanine/polymalonate route, the last and key enzyme of this pathway being stilbene synthase. Here, we review the biological significance of stilbenes in plants together with their biosynthesis pathway and their metabolism both by fungi and in planta. Special attention will be paid to the role of stilbenic molecules as phytoalexins.
authors: UPRES EA, University of Reims, France. philippe.jeandet@univ-reims.fr
authors: Philippe
authors: P
authors: Jeandet
authors: Bertrand
authors: B
authors: Delaunois
authors: Alexandra
authors: A
authors: Conreux
authors: David
authors: D
authors: Donnez
authors: Vitale
authors: V
authors: Nuzzo
authors: Sylvain
authors: S
authors: Cordelier
authors: Christophe
authors: C
authors: Clément
authors: Eric
authors: E
authors: Courot
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000502:physiology; D000217:Acyltransferases / Q000378:metabolism; D000935:Antifungal Agents / Q000494:pharmacology; D005658:Fungi / Q000472:pathogenicity; D005818:Genetic Engineering; D010944:Plants / Q000378:metabolism*; D000077185:Resveratrol; D012717:Sesquiterpenes / Q000378:metabolism* / Q000494:pharmacology; D013267:Stilbenes / Q000378:metabolism*; D000094162:Phytoalexins
chemical_list: D018528:ATP-Binding Cassette Transporters; D000935:Antifungal Agents; D012717:Sesquiterpenes; D013267:Stilbenes; D000217:Acyltransferases; C022674:stilbene synthase; D000077185:Resveratrol; D000094162:Phytoalexins