[Study of CO(2) pneumoperitoneum on the level of vWF in pregnancy rats].
OBJECTIVE
The goal of this paper is to study changes of von Willebrand Factor in medium and late pregnancy rats' serum during diffencet time and pressure of CO(2) pneumoperitoneum.


METHODS
By solid phase phase sandwich enzyme linked immuno sorbent assay (ELISA).


RESULTS
(1) We succeed to build the model of carbon dioxide pneumoperitoneum in medium pregnancy rats. (2) The time and pressure of carbon dioxide pneumoperitoneum was proportional to von Willebrand Factor in serum, they have no statistical significance (P>0.05).


CONCLUSIONS
It is safity to operate in medium pregnancy by laparoscopic surgery. But we must control the time in 2 hours.
Zhang
Ying
Y
Department of Obstetric and Gynecology, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China. zhangying5413@126.com
Liao
Jing
J
D000818:Animals; D002245:Carbon Dioxide / Q000009:adverse effects*; D005260:Female; D011027:Pneumoperitoneum / Q000139:chemically induced / Q000378:metabolism*; D011247:Pregnancy; D011897:Random Allocation; D051381:Rats; D014841:von Willebrand Factor / Q000378:metabolism*
D014841:von Willebrand Factor; D002245:Carbon Dioxide