title: Stroke in a young boy with β-thalassemia intermedia secondary to moyamoya syndrome.
abstract: Moyamoya disease is a rare cerebrovascular disorder, characterized by stenosis or occlusion of cerebral arteries. Well described with sickle cell anemia, its association with other hemoglobinopathies is a rarity. We report a 5-year-old boy with β-thalassemia intermedia, on hydroxyurea therapy, who presented with a stroke. Magnetic resonance angiography findings were consistent with bilateral moyamoya disease. The literature with regard to the pathogenesis and options of management is reviewed.
authors: Division of Hematology-Oncology, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors: Sapna
authors: S
authors: Oberoi
authors: Deepak
authors: D
authors: Bansal
authors: Paramjeet
authors: P
authors: Singh
authors: Ram K
authors: RK
authors: Marwaha
mesh_terms: D002533:Cerebral Angiography; D002675:Child, Preschool; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D009072:Moyamoya Disease / Q000150:complications* / Q000473:pathology; D020521:Stroke / Q000209:etiology* / Q000473:pathology; D017086:beta-Thalassemia / Q000150:complications*