Trends in the bioanalytical applications of microfluidic electrocapture.
Downscaled analytical tools for sample preparation have offered benefits such as higher throughput, easier automation and lower sample/reagent consumption. Microfluidic electrocapture, which is a newly developed sample preparation/manipulation system, uses an electric field to trap and separate charged species without using any solid sorbent. The feasibility of using microfluidic electrocapture is reported for separation, clean-up, concentration, microreactions and complexation studies of proteins, peptides and other biologically important biomolecules. The instrumentation and applications of microfluidic electrocapture are reviewed and an overview is provided of future perspectives offered by the current and envisaged platforms.
Shariatgorji
Mohammadreza
M
Department of Analytical Chemistry, Stockholm University, 10691 Stockholm, Sweden. reza.shariatgorji@farmbio.uu.se
Astorga-Wells
Juan
J
Ilag
Leopold L
LL
D000818:Animals; D004867:Equipment Design; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods / Q000639:trends*; D010455:Peptides / Q000032:analysis; D011506:Proteins / Q000032:analysis
D010455:Peptides; D011506:Proteins