title: Clinical risk factors for invasive aspergillosis.
abstract: Despite improvements in the antifungal armamentarium and diagnostic modalities, invasive aspergillosis (IA) remains an important cause of morbidity and mortality in immunocompromised patients. There is an emergence of non-traditional groups at risk for IA, including intensive care unit (ICU) patients, post-operative patients, those with chronic pulmonary diseases, patients with AIDS and patients on immunomodulating drugs (TNF-α inhibitors). Identification of clinical risk factors for IA may help in determining which patients require risk modification and other prevention measures.
authors: University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, 1900 University Boulevard, Birmingham, AL 35294, USA. jbaddley@uab.edu
authors: John W
authors: JW
authors: Baddley
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D001228:Aspergillosis / Q000209:etiology* / Q000276:immunology / Q000517:prevention & control*; D001230:Aspergillus / Q000472:pathogenicity; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007362:Intensive Care Units; D016377:Organ Transplantation / Q000009:adverse effects; D011183:Postoperative Complications / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D012307:Risk Factors; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha