title: Synthesis of the fluorescent amino acid rac-(7-hydroxycoumarin-4-yl)ethylglycine.
abstract: The hydrochloride of the racemic amino acid (7-hydroxycoumarin-4-yl)ethylglycine, a versatile fluorescent probe in proteins, has been synthesized in five steps from commercially available (7-hydroxycoumarin-4-yl)acetic acid. The key step involves the alkylation of a glycine-enolate equivalent.
authors: Institute of Organic and Macromolecular Chemistry, University of Düsseldorf, Universitätsstr. 1, D-40225 Düsseldorf, Germany. braunm@uni-duesseldorf.de
authors: Manfred
authors: M
authors: Braun
authors: Torsten
authors: T
authors: Dittrich