title: The effect of early infection with Echinostoma paraensei on the interaction of Schistosoma mansoni with Biomphalaria glabrata and Biomphalaria tenagophila.
abstract: Infection caused by the trematode Echinostoma paraensei has been shown to interfere in the natural resistance to infection by Schistosoma mansoni. Biomphalaria glabrata is susceptible to infection, while Taim isolate Biomphalaria tenagophila is resistant to infection by S. mansoni. These two snail species were assessed for infection with E. paraensei two days after exposure to S. mansoni miracidia. The number of B. tenagophila and B. glabrata infected with E. paraensei was lower in co-infected group, suggesting an antagonistic relationship. B. glabrata showed an increase in its susceptibility to S. mansoni, whereas B. tenagophila maintained its refractoriness to S. mansoni infection. Weekly comparisons made between the E. paraensei cercariae released from B. tenagophila and B. glabrata mono-infected snails revealed no quantitative differences. In contrast, S. mansoni cercariae released were higher in the B. glabrata co-infected group. Mortality rates were significantly greater in both species pertaining to co-infected group and unexpected mortalities were also observed in B. tenagophila exposed only to S. mansoni miracidia. Our study revealed that the B. tenagophila Taim isolate is susceptible to E. paraensei infection, although infection did not alter its resistance to S. mansoni infection.
authors: Laboratório de Malacologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brasil.
authors: Juberlan Silva
authors: JS
authors: Garcia
authors: Arnaldo
authors: A
authors: Maldonado Junior
authors: Cláudio Juan
authors: CJ
authors: Bidau
authors: Ligia dos Reis
authors: Ldos R
authors: Corrêa
authors: Reinalda Marisa
authors: RM
authors: Lanfredi
authors: Paulo Marcos Zech
authors: PM
authors: Coelho
mesh_terms: D000818:Animals; D001700:Biomphalaria / Q000276:immunology / Q000469:parasitology*; D004449:Echinostoma / Q000276:immunology / Q000502:physiology*; D006790:Host-Parasite Interactions / Q000276:immunology*; D007113:Immunity, Innate; D051379:Mice; D012377:Rodentia; D012550:Schistosoma mansoni / Q000276:immunology / Q000502:physiology*; D012555:Schistosomiasis mansoni / Q000276:immunology*; D013997:Time Factors