Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS.
Irschik
Herbert
H
Microbial Drugs, Helmholtz Center for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Kopp
Maren
M
Weissman
Kira J
KJ
Buntin
Kathrin
K
Piel
Jörn
J
Müller
Rolf
R
D000617:Aminoglycosides / Q000096:biosynthesis* / Q000737:chemistry / Q000235:genetics; D020134:Catalytic Domain; D005810:Multigene Family; D009231:Myxococcales / Q000201:enzymology / Q000235:genetics; D010802:Phylogeny; D048630:Polyketide Synthases / Q000145:classification / Q000235:genetics* / Q000378:metabolism
D000617:Aminoglycosides; C051799:sorangicin A; C052000:sorangicin B; D048630:Polyketide Synthases