64-channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation.
Micropigs are the most likely source animals for xenotransplantation. However, an appropriate method for evaluating the lung of micropigs had not been established. Therefore, this study was performed to evaluate the feasibility of 64-channel multi-detector row computed tomography (MDCT) to measure the diameter of the pulmonary arteries and the lung volume in micropigs. The mean diameters of the trachea, and left and right bronchi were 1.6 +/- 0.17, 1.18 +/- 0.14, and 1.1 +/- 0.11 cm, respectively. The mean diameters of the main, right, and left pulmonary arteries were 1.38 +/- 0.09, 1.07 +/- 0.26, and 0.98 +/- 0.13 cm and the diameters of right, left, and common inferior pulmonary veins were 0.97 +/- 0.20, 0.76 +/- 0.20, and 1.99 +/- 0.26 cm, respectively. The mean lung volume was 820.3 +/- 77.11 mL. The data presented in this study suggest that the MDCT may be a noninvasive, rapid, and accurate investigational method for pulmonary anatomy in living lung donors.
Yoon
Woong
W
Department of Radiology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 501-746, Korea.
Ryu
Jung Min
JM
Lee
Min Young
MY
Moon
Yong Ju
YJ
Lee
Sang Hun
SH
Park
Jae Hong
JH
Yun
Seung Pil
SP
Jang
Min Woo
MW
Park
Sung Su
SS
Han
Ho Jae
HJ
D000818:Animals; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000502:physiology; D009929:Organ Size / Q000502:physiology; D011651:Pulmonary Artery / Q000000981:diagnostic imaging* / Q000502:physiology; D013552:Swine; D013556:Swine, Miniature / Q000033:anatomy & histology*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014183:Transplantation, Heterologous / Q000379:methods*