[Analysis on HBV epidemical trend of people age <20 from rural areas of Zhaodong].
OBJECTIVE
By two times investigation to the HBV infection of people age <20 in rural areas in Zhaodong city, to understand the effects of HepB immunigation through analysing the changes of HBsAg, anti-HBs and anti-HBc infectious markers during 1986-2005.


METHODS
Cross-sectional study was conducted and the surum samples were collected in 1986 and 2005 respectively. HBsAg, anti-HBs and anti-HBc of the sera with SPRIA were tested.


RESULTS
HBsAg average positive rate of the people age <20 decreased from 8.5% in 1986 to 4.4% in 2005 (chi2 = 10.88, P < 0.01). The anti-HBs average positive rate increased to 43.1% in 2005 from 18.3% in 1986 (chi2 = 130.47, P < 0.01). The anti-HBc average positive rate decreased from 39.9% to 15.1% (chi2 = 122.18, P < 0.01).


CONCLUSIONS
The HBV infectious background of the rural population in Zhaodong city is high and the HBV infection rate decreased obviously after HepB inoculation since 1986, but it is still higher than the state average rate. It indicated that the HBV prevention in this district need to be enforced and improved.
Wang
Feng
F
State Key Laboratory for Infectious Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.
Liu
Yan-cheng
YC
Wang
Kai-li
KL
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000097:blood / Q000276:immunology; D006511:Hepatitis B Antigens / Q000097:blood / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D011159:Population Surveillance; D012423:Rural Health / Q000706:statistics & numerical data / Q000639:trends; D055815:Young Adult
D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D017325:Hepatitis B Vaccines