title: Ultrasound-assisted synthesis of 2,2'-(2-oxoindoline-3,3-diyl)bis(1H-indene-1,3(2H)-dione) derivatives.
abstract: A simple and efficient procedure for the synthesis of 2,2'-(2-oxoindoline-3,3-diyl)bis(1H-indene-1,3(2H)-dione) derivatives, 2,2'-(2-oxo-1,2-dihydroacenaphthylene-1,1-diyl)bis(1H-indene-1,3(2H)-dione) and 2,2'-(1,3-dioxo-2,3-dihydro-1H-indene-2,2-diyl)bis(1H-indene-1,3(2H)-dione) by the reaction of 1,3-indandione and isatins or acenaphthylene-1,2-dione or ninhydrine in ethanol under ultrasonic irradiation in the presence of p-TSA is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of ethanol as a solvent that is considered to be relatively environmentally benign.
authors: Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
authors: Ramin
authors: R
authors: Ghahremanzadeh
authors: Fatemeh
authors: F
authors: Fereshtehnejad
authors: Peiman
authors: P
authors: Mirzaei
authors: Ayoob
authors: A
authors: Bazgir
mesh_terms: D000073:Acenaphthenes / Q000138:chemical synthesis* / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D014465:Ultrasonics
chemical_list: D000073:Acenaphthenes; D007192:Indenes