PML promotes senescence via JAK/STAT signaling.
Krämer
Alwin
A
University of Heidelberg, Heidelberg, Germany. a.kraemer@dkfz.de
D000970:Antineoplastic Agents / Q000494:pharmacology; D016922:Cellular Senescence / Q000187:drug effects; D015973:Gene Expression Regulation, Leukemic / Q000187:drug effects; D006801:Humans; D053613:Janus Kinase 1 / Q000378:metabolism*; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D000071156:Promyelocytic Leukemia Protein; D020218:Response Elements / Q000235:genetics; D050791:STAT Transcription Factors / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism*
D000970:Antineoplastic Agents; D009687:Nuclear Proteins; D000071156:Promyelocytic Leukemia Protein; D050791:STAT Transcription Factors; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; C070576:PML protein, human; D053613:Janus Kinase 1