title: Histological evaluation of bone repair using β-tricalcium phosphate.
abstract: OBJECTIVE
  The aim of the present study was to evaluate bone repair in defects induced in the cranium of Wistar rats using β-tricalcium phosphate.
  
  
  METHODS
  In this research, we used 30 rats, randomly distributed in three groups of 10 animals (G1, G2 and G3), corresponding respectively to time of histological evaluation (7, 15 and 30 days). This was a paired study, a defect being induced in the parietal bone on either side of the median sagittal suture of the animals, being the left-hand side the experimental subgroup (filled by biomaterial) and the right control. The histological evaluation was performed by means of light microscopy. The collected data were submitted to the Fisher Exact test for comparison between the groups and to the McNemar test for comparison between the subgroups (P > 5%).
  
  
  RESULTS
  The results showed no statistically significant differences between the groups and bone regeneration was similar at the different times of evaluation.
  
  
  CONCLUSIONS
  Therefore, we concluded that β-tricalcium phosphate has not contributed significantly to repair process of defects induced in the cranium of Wistar rats.
authors: Program in Oral and Maxillofacial Surgery, FOP/UPE, Brazil. riedelfrota@uol.com.br
authors: Riedel
authors: R
authors: Frota
authors: Valdemiro-Amaro
authors: VA
authors: Da Silva-Júnior
authors: Marcelo
authors: M
authors: Teixeira
authors: Ana-Paula-Veras
authors: AP
authors: Sobral
authors: Emanuel-Dias-de Oliveira e Silva
authors: Márcia-María-Fonseca
authors: MM
authors: Da Silveira
authors: Adelmo-Cavalcanti
authors: AC
authors: Aragão-Neto
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D002130:Calcium Phosphates; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate