Sensing of bacterial endotoxin in aqueous solution by supramolecular assembly of pyrene derivative.
N,N-dimethyl-N-(pyrenyl-1-methyl) dodecan-1-ammonium has been designed and applied as a fluorescent probe for sensing bacterial endotoxin. Upon assembly with bacterial endotoxin (lipopolysaccharide) in aqueous solution, the probe exhibits a ratiometric and sensitive fluorescence response with a low detection limit (100 nM). Moreover, the probe shows high selectivity for bacterial endotoxin over other related biological species.
Zeng
Lintao
L
Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.
Wu
Jiasheng
J
Dai
Qing
Q
Liu
Weimin
W
Wang
Pengfei
P
Lee
Chun-Sing
CS
D004731:Endotoxins / Q000032:analysis*; D015394:Molecular Structure; D011721:Pyrenes / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000032:analysis* / Q000737:chemistry; D012996:Solutions / Q000737:chemistry
D004731:Endotoxins; D011721:Pyrenes; D000644:Quaternary Ammonium Compounds; D012996:Solutions