An efficient approach to functionalized benzo[a]xanthones through reactions of 2-methyl-3-(1-alkynyl)chromones with electron-deficient chromone-fused dienes.
An efficient tandem process was developed to synthesize diversified benzo[a]xanthones from 2-methyl-3-(1-alkynyl)chromones with electron-deficient chromone-fused dienes. This unusual reaction, involving multiple steps and not requiring the use of transition metal catalysts or an inert atmosphere, results in the formation of three new C-C bonds and one C-O bond.
Gong
Jian
J
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, 555 Zu Chong Zhi Road, Shanghai 201203, China.
Xie
Fuchun
F
Chen
Hong
H
Hu
Youhong
Y
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D002867:Chromones / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D044004:Xanthones / Q000138:chemical synthesis* / Q000737:chemistry
D000480:Alkynes; D002867:Chromones; D044004:Xanthones