Chest radiography and CT findings in patients with the 2009 pandemic (H1N1) influenza.
OBJECTIVE
To present chest radiography and thoracic computed tomography (CT) findings for patients with pandemic influenza A (H1N1) from November-December 2009 and to explore any differences compared to previously reported imaging findings.


METHODS
Fifty-two hospitalized patients with pandemic influenza (H1N1) were included in the study. All of the patients underwent chest radiography, and 28 patients were also evaluated by thoracic CT. Group 1 comprised 24 (46%) patients with no identified risk factors for H1N1 influenza infection. Group 2 comprised the remaining 28 (54%) patients with identified risk factors. The distribution of lung involvement, consolidation, ground-glass opacity (GGO), lymph nodes, and pleural effusion were evaluated.


RESULTS
Abnormal findings were observed in 85% of the patients. Bilateral lung involvement was present in 80% of the patients. The most common finding was a mixture of GGO and air-space consolidation. Lower zone predominance occurred in 89% of group 1 and 85% of group 2 patients. The involvement was observed most frequently in the peripheral and central perihilar areas of the lung in 80% of the patients. The extent of disease was greater in group 2 patients with the involvement of three or more lung zones in 62% of the patients.


CONCLUSIONS
The most common imaging finding for lung involvement was a mixture of air-space consolidation and GGO with a patchy pattern and lower/middle zone predominance. Pulmonary involvement of the disease was more extensive than that described in previous reports.
Karadeli
Elif
E
Department of Radiology, Başkent University Faculty of Medicine, Adana Teaching and Medical Research Center, Adana, Turkey. elifkaradeli@gmail.com
Koç
Zafer
Z
Ulusan
Serife
S
Erbay
Gürcan
G
Demiroğlu
Yusuf Ziya
YZ
Sen
Nazan
N
D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000821:virology; D008297:Male; D008875:Middle Aged; D058873:Pandemics / Q000706:statistics & numerical data; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D011379:Prognosis; D013902:Radiography, Thoracic / Q000379:methods*; D018570:Risk Assessment; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult