title: Synthesis of polysubstituted dihydropyridines by four-component reactions of aromatic aldehydes, malononitrile, arylamines, and acetylenedicarboxylate.
abstract: A practical and efficient procedure for the preparation of the polysubstituted dihydropyridines was developed through a unique four-component reaction of aromatic aldehydes, malononitrile, arylamines, and acetylenedicarboxylate in ethanol in the presence of triethylamine as a base promoter. This four-component reaction is atom-efficient, high-yielding, and applicable to a wide variety of four-component reactions.
authors: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors: Jing
authors: J
authors: Sun
authors: Er-Yan
authors: EY
authors: Xia
authors: Qun
authors: Q
authors: Wu
authors: Chao-Guo
authors: CG
authors: Yan