title: Co-occurring psychiatric symptoms are associated with increased psychological, social, and medical impairment in opioid dependent pregnant women.
abstract: The interaction of psychiatric symptoms with drug dependence during pregnancy is not well understood. This study examines the relationship of psychiatric symptoms to severity of drug use and drug-related problems among participants in a clinical trial of pharmacologic treatment of opioid dependence during pregnancy (N = 174). A total of 64.6% reported additional psychiatric symptoms (48.6% mood symptoms, 40.0% anxiety symptoms, and 12.6% suicidal thinking). Women who endorsed co-occurring psychiatric symptoms showed more severe impairment on the Addiction Severity Index. Further investigation is warranted to understand the effect of psychiatric symptoms on long-term maternal and neonatal outcomes.
authors: Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee 37216, USA. meg.benningfield@vanderbilt.edu
authors: Margaret M
authors: MM
authors: Benningfield
authors: Amelia M
authors: AM
authors: Arria
authors: Karol
authors: K
authors: Kaltenbach
authors: Sarah H
authors: SH
authors: Heil
authors: Susan M
authors: SM
authors: Stine
authors: Mara G
authors: MG
authors: Coyle
authors: Gabriele
authors: G
authors: Fischer
authors: Hendrée E
authors: HE
authors: Jones
authors: Peter R
authors: PR
authors: Martin
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D017831:Diagnosis, Dual (Psychiatry) / Q000523:psychology; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000150:complications / Q000453:epidemiology* / Q000523:psychology*; D009293:Opioid-Related Disorders / Q000150:complications / Q000523:psychology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology*; D015995:Prevalence; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index