MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.
The design and features of a beamline control software system for macromolecular crystallography (MX) experiments developed at the European Synchrotron Radiation Facility (ESRF) are described. This system, MxCuBE, allows users to easily and simply interact with beamline hardware components and provides automated routines for common tasks in the operation of a synchrotron beamline dedicated to experiments in MX. Additional functionality is provided through intuitive interfaces that enable the assessment of the diffraction characteristics of samples, experiment planning, automatic data collection and the on-line collection and analysis of X-ray emission spectra. The software can be run in a tandem client-server mode that allows for remote control and relevant experimental parameters and results are automatically logged in a relational database, ISPyB. MxCuBE is modular, flexible and extensible and is currently deployed on eight macromolecular crystallography beamlines at the ESRF. Additionally, the software is installed at MAX-lab beamline I911-3 and at BESSY beamline BL14.1.
Gabadinho
José
J
European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble, France.
Beteva
Antonia
A
Guijarro
Matias
M
Rey-Bakaikoa
Vicente
V
Spruce
Darren
D
Bowler
Matthew W
MW
Brockhauser
Sandor
S
Flot
David
D
Gordon
Elspeth J
EJ
Hall
David R
DR
Lavault
Bernard
B
McCarthy
Andrew A
AA
McCarthy
Joanne
J
Mitchell
Edward
E
Monaco
Stéphanie
S
Mueller-Dieckmann
Christoph
C
Nurizzo
Didier
D
Ravelli
Raimond B G
RB
Thibault
Xavier
X
Walsh
Martin A
MA
Leonard
Gordon A
GA
McSweeney
Sean M
SM
D002265:Carboxylic Ester Hydrolases / Q000737:chemistry; D018360:Crystallography, X-Ray / Q000379:methods*; D016208:Databases, Factual; D046911:Macromolecular Substances / Q000737:chemistry; D012984:Software; D013052:Spectrometry, X-Ray Emission; D017356:Synchrotrons; D013820:Thermolysin / Q000737:chemistry
D046911:Macromolecular Substances; D002265:Carboxylic Ester Hydrolases; C070196:feruloyl esterase; D013820:Thermolysin