title: Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers.
abstract: OBJECTIVE
  This trial examined the efficacy of teacher-delivered personality-targeted interventions for alcohol-misuse over a 6-month period.
  
  
  METHODS
  This randomized controlled trial randomly allocated participating schools to intervention (n = 11) or control (n = 7) conditions. A total of 2,506 (mean age, 13.7 years) were assessed for elevated levels of personality risk factors for substance misuse: sensation-seeking, impulsivity, anxiety sensitivity, and hopelessness. Six hundred ninety-six adolescents were invited to participate in teacher-delivered personality-targeted interventions, and 463 were assigned to the nontreatment condition. Primary outcomes were drinking, binge-drinking status, quantity by frequency of alcohol use, and drinking-related problems.
  
  
  RESULTS
  School delivery of the personality-targeted intervention program was associated with significantly lower drinking rates in high-risk students at 6-month follow-up (odds ratio, 0.6), indicating a 40% decreased risk of alcohol consumption in the intervention group. Receiving an intervention also predicted significantly lower binge-drinking rates in students who reported alcohol use at baseline (odds ratio, 0.45), indicating a 55% decreased risk of binge-drinking in this group compared with controls. In addition, high-risk intervention-school students reported lower quantity by frequency of alcohol use (beta = -.18) and drinking-related problems (beta = -.15) compared with the nontreatment group at follow-up.
  
  
  CONCLUSIONS
  This trial replicates previous studies reporting the efficacy of personality-targeted interventions and demonstrates that targeted interventions can be successfully delivered by teachers, suggesting potential for this approach as a sustainable school-based prevention model. Clinical trial registration information-Personality-Targeted Interventions for Adolescent Alcohol Misuse, URL: http://www.clinicaltrials.gov, unique identifier: NCT00344474.
authors: Institute of Psychiatry, King's College London, and the South London and Maudsley National Health Service Foundation Trust, London, United Kingdom.
authors: Maeve
authors: M
authors: O'Leary-Barrett
authors: Clare J
authors: CJ
authors: Mackie
authors: Natalie
authors: N
authors: Castellanos-Ryan
authors: Nadia
authors: N
authors: Al-Khudhairy
authors: Patricia J
authors: PJ
authors: Conrod
mesh_terms: D000293:Adolescent; D000428:Alcohol Drinking / Q000517:prevention & control* / Q000523:psychology; D000435:Alcoholic Intoxication / Q000517:prevention & control* / Q000523:psychology; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology; D002605:Character; D015928:Cognitive Behavioral Therapy; D005106:Exploratory Behavior; D005260:Female; D006266:Health Education / Q000379:methods*; D006801:Humans; D007175:Impulsive Behavior / Q000517:prevention & control / Q000523:psychology; D007206:Individuality; D007318:Inservice Training; D008131:London; D008297:Male; D009042:Motivation; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011594:Psychometrics; D012307:Risk Factors