Effect of glutamine supplementation on lymphocyte subsets in children with acute diarrhea.
To study the effect of glutamine supplementation on lymphocyte subpopulation counts in children with acute diarrhea, children aged 6-24 months were enrolled in a double-blind randomized study. Cases had received either 0.3 g/kg/day of glutamine or placebo orally for seven days. The counts of blood leukocytes, lymphocytes and lymphocyte subpopulations (CD3+, CD4+, CD8+, CD19+, CD16+CD56+) were determined both on admission and seven days later using a flow cytometry. When adjusting for sex, current breastfeeding status, dehydration, and nutritional status of children, lymphocyte subpopulations did not differ significantly between the glutamine- and placebo-supplemented groups on the 7th day of intervention.
Yalçin
S Songül
SS
Unit of Social Pediatrics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Yurdakök
Kadriye
K
Tezcan
Ilhan
I
Tuncer
Murat
M
D003968:Diarrhea, Infantile / Q000097:blood*; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D005973:Glutamine / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D016131:Lymphocyte Subsets / Q000187:drug effects*; D008297:Male; D011446:Prospective Studies
D005973:Glutamine