title: Effects of five parent-and-child risk factors on salivary cortisol levels and symptoms of posttraumatic stress disorder in school-age, critically ill children: pilot study.
abstract: OBJECTIVE
  We examined the contributions of risk factors to the psychological and neuroendocrine status of children admitted to a pediatric intensive care unit (PICU), and explored the feasibility of a full-scale study of these risk factors.
  
  
  METHODS
  A prospective, correlational design was used. Risk factors included parental stress, parental anxiety, child anxiety, severity of the child's illness, and invasive procedures administered to the child. Outcomes variables were pediatric posttraumatic stress disorder (PTSD) symptoms and salivary cortisol levels. Measures were taken at 3 time points over 3 months.
  
  
  RESULTS
  The mothers' state anxiety significantly increased over time, whereas the children's PTSD symptoms decreased. Most children with average or high anxiety demonstrated varying degrees of PTSD symptomatology, whereas children with low anxiety exhibited doubtful or mild symptoms of PTSD. As the severity of PTSD symptoms increased over time, the level of salivary cortisol decreased at two weeks and three months after hospital discharge.
  
  
  CONCLUSIONS
  Predicted trends in data were found and warrant further investigation, using a similar methodology in a full-scale study with an emphasis on recruiting the most seriously ill children.
authors: School of Nursing, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, USA. r.board@neu.edu
authors: Rhonda
authors: R
authors: Board
authors: Jianyu
authors: J
authors: Dai
mesh_terms: D000328:Adult; D001007:Anxiety / Q000150:complications / Q000451:nursing / Q000523:psychology; D001143:Arousal / Q000502:physiology; D002648:Child; D016638:Critical Illness / Q000451:nursing* / Q000523:psychology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D010287:Parent-Child Relations; D010552:Personality Assessment / Q000706:statistics & numerical data; D010865:Pilot Projects; D011594:Psychometrics; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry; D013313:Stress Disorders, Post-Traumatic / Q000451:nursing* / Q000523:psychology*; D013315:Stress, Psychological / Q000150:complications / Q000451:nursing / Q000523:psychology
chemical_list: D006854:Hydrocortisone