A novel synthetic route for the anti-HIV drug MC-1220 and its analogues.
Loksha
Yasser M
YM
Nucleic Acid Center, Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Globisch
Daniel
D
Loddo
Roberta
R
Collu
Gabriella
G
La Colla
Paolo
P
Pedersen
Erik B
EB
D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005464:Fluorobenzenes; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors / Q000378:metabolism; D015497:HIV-1 / Q000145:classification / Q000187:drug effects*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
C506288:6-(1-(2,6-difluorophenyl)ethyl)-2-(dimethylamino)-5-methylpyrimidin-4(3H)-one; D019380:Anti-HIV Agents; D005464:Fluorobenzenes; D011744:Pyrimidinones; D054303:HIV Reverse Transcriptase