title: The effect of isotonic multiple electrolyte infusions during anesthesia on blood gas and enzymatic values in horses.
abstract: General equine anesthesia is accompanied by the risk of complications and even death. The majority of general anesthetics used in veterinary practice lead to arterial hypotension, decreased capillary perfusion and ventilatory depression leading to pathological changes referred to as postanesthetic myopathy. In this study an attempt was made to analyze changes in the perioperative and postoperative acid-base equilibrium and blood enzymatic activity in horses, subject to the intensity of the applied fluid therapy. The horses were divided into two groups: I--administered Ringer's solution during surgery at a dose of 6-10 ml/kg BW/h, II--Ringer's solution administered at a dose of 12-15 ml/kg BW/h. The results of the study indicate that use of hydrating fluid infusions during general anesthesia, including infusions without hypertensive substances, minimizes the risk of myocyte damage due to disturbances in local and general blood circulation.
authors: Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland. astopyra@uwm.edu.pl
authors: A
authors: A
authors: Stopyra
authors: M
authors: M
authors: Jałyński
authors: P
authors: P
authors: Sobiech
authors: M
authors: M
authors: Chyczewski
authors: P
authors: P
authors: Holak
authors: M
authors: M
authors: Lew
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary*; D001794:Blood Pressure; D004305:Dose-Response Relationship, Drug; D004573:Electrolytes / Q000008:administration & dosage / Q000494:pharmacology; D004798:Enzymes / Q000097:blood*; D005260:Female; D006736:Horses / Q000097:blood*; D007552:Isotonic Solutions / Q000008:administration & dosage* / Q000494:pharmacology*; D008297:Male; D009135:Muscular Diseases / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary; D011183:Postoperative Complications / Q000517:prevention & control / Q000662:veterinary; D000077331:Ringer's Solution
chemical_list: D004573:Electrolytes; D004798:Enzymes; D007552:Isotonic Solutions; D000077331:Ringer's Solution