title: Polymorphisms and allele frequencies of the ABO blood group gene among the Jomon, Epi-Jomon and Okhotsk people in Hokkaido, northern Japan, revealed by ancient DNA analysis.
abstract: To investigate the genetic characteristics of the ancient populations of Hokkaido, northern Japan, polymorphisms of the ABO blood group gene were analyzed for 17 Jomon/Epi-Jomon specimens and 15 Okhotsk specimens using amplified product-length polymorphism and restriction fragment length polymorphism analyses. Five ABO alleles were identified from the Jomon/ Epi-Jomon and Okhotsk people. Allele frequencies of the Jomon/Epi-Jomon and Okhotsk people were compared with those of the modern Asian, European and Oceanic populations. The genetic relationships inferred from principal component analyses indicated that both Jomon/Epi-Jomon and Okhotsk people are included in the same group as modern Asian populations. However, the genetic characteristics of these ancient populations in Hokkaido were significantly different from each other, which is in agreement with the conclusions from mitochondrial DNA and ABCC11 gene analyses that were previously reported.
authors: Graduate School of Science, Hokkaido University, Sapporo, Japan.
authors: Takehiro
authors: T
authors: Sato
authors: Hisako
authors: H
authors: Kazuta
authors: Tetsuya
authors: T
authors: Amano
authors: Hiroko
authors: H
authors: Ono
authors: Hajime
authors: H
authors: Ishida
authors: Haruto
authors: H
authors: Kodera
authors: Hirofumi
authors: H
authors: Matsumura
authors: Minoru
authors: M
authors: Yoneda
authors: Yukio
authors: Y
authors: Dodo
authors: Ryuichi
authors: R
authors: Masuda
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D001106:Archaeology; D044466:Asian People / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D049690:History, Ancient; D006801:Humans; D007564:Japan; D011110:Polymorphism, Genetic; D025341:Principal Component Analysis
chemical_list: D000017:ABO Blood-Group System