title: Cutaneous features predict paraspinal neurofibromas in neurofibromatosis type 1.
abstract: In neurofibromatosis type 1 (NF-1), malignant transformation of internal plexiform neurofibromas carries a poor prognosis, in part because they are not evident clinically. In this issue, Sbidian et al. describe a novel "NF-1Score" equation that employs four easily observable traits to predict the presence of paraspinal neurofibromas. This tool can identify at-risk patients during regular screening to help reduce mortality.
authors: Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
authors: Rebecca M
authors: RM
authors: Brown
authors: Laura J
authors: LJ
authors: Klesse
authors: Lu Q
authors: LQ
authors: Le
mesh_terms: D002471:Cell Transformation, Neoplastic; D018450:Disease Progression; D006801:Humans; D009456:Neurofibromatosis 1 / Q000401:mortality* / Q000473:pathology*; D011237:Predictive Value of Tests; D012307:Risk Factors; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000401:mortality* / Q000473:pathology*