F-18 FDG PET/CT findings in pulmonary necrotizing sarcoid granulomatosis.
Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease that was described by Liebow in 1973. Dyspnea and chest pain may be present, as in our first patient; however, 25% of patients are asymptomatic, as our second patient. The typical radiographic findings are nonspecific: single or multiple lung opacities, with common involvement of the pleura. To the best of our knowledge, fluorodeoxyglucose (FDG) PET has only been reported in one case of NSG, which was atypical as it occurred in an adolescent. We report 2 cases, confirming that the lesions of NSG are FDG positive, showing a typical pattern of multiple bilateral lung nodules (imaged with PET/CT in 1 case). FDG imaging has a potential role when this distribution is observed on CT, to guide the surgical biopsy and show the actual extent of the disease.
Arfi
Julia
J
Department of Nuclear Medicine, Hôpital Tenon, Université Pierre et Marie Curie, Paris, France.
Kerrou
Khaldoun
K
Traore
Samba
S
Huchet
Virginie
V
Bolly
Antoine
A
Antoine
Martine
M
Delaunois
Luc
L
Vander Borght
Thierry
T
Talbot
Jean-Noël
JN
D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D049268:Positron-Emission Tomography; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D019788:Fluorodeoxyglucose F18