title: Styrylpyrones from the medicinal fungus Phellinus baumii and their antioxidant properties.
abstract: During the search for natural antioxidants from basidiomycetes, a new styrylpyrone, baumin (1), was isolated from the cultivated medicinal fungus Phellinus baumii, together with known compounds, davallialactone (2), hispidin (3), hypholomine B (4), interfungin A (5), inoscavin A (6), and phelligridin D (7), which were previously isolated from the medicinal fungi Phellinusignarius, Phellinuslinteus, and Inonotus xeranticus. Their structures were elucidated by extensive spectroscopic methods. These compounds exhibited antioxidant activity through Fenton reaction inhibition via iron chelation and free radical scavenging.
authors: Division of Biotechnology, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan, Jeonbuk 570-752, Republic of Korea.
authors: In-Kyoung
authors: IK
authors: Lee
authors: Myung-Suk
authors: MS
authors: Han
authors: Myeong-Seok
authors: MS
authors: Lee
authors: Young-Sook
authors: YS
authors: Kim
authors: Bong-Sik
authors: BS
authors: Yun
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001487:Basidiomycota / Q000737:chemistry*; D004247:DNA / Q000378:metabolism; D053904:DNA Breaks, Single-Stranded / Q000187:drug effects; D007501:Iron / Q000378:metabolism; D007502:Iron Chelating Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D007502:Iron Chelating Agents; D011753:Pyrones; D004247:DNA; D007501:Iron