title: [Role of immunologic abnormality in recurrent parotitis in children].
abstract: To investigate the relationship between immune function and the recurrent parotitis (RP) for children.
  
  
  
  The children diagnosed as RP were divided into two groups: aged under 6y and over 6y and the immune function were measured and compared with that of normal children.
  
  
  
  For RP children the ratio of CD4+ T cell in over 6y group was significantly lower than that in under 6y group (P<0.05), while IgG value in over 6y group was higher than that in under 6y group (P<0.05). Compared with normal children, RP children in under 6y group had higher CD8+ T cell ratio and IgG, IgE, IgA and C3 value (P<0.01) and lower CD4+ T cell ratio (P<0.01), while RP children over 6y group, they had higher CD8+ T cell ratio, IgE value (P<0.01) and C3 (P<0.05), lower CD4<T cell ratio than those in control group (P<0.01). IgE value and CD8+ T cell ratio in under 6y group were higher than those over 6y control group (P<0.01).
  
  
  
  Impaired immune function may play an important role in the recurrent parotitis in children.
authors: Department of Stomatology, The Affiliated Children's Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. ruanwh@hzcnc.com
authors: Wen-hua
authors: WH
authors: Yuan
authors: Ji-mei
authors: JM
authors: Su
authors: Xiao-wei
authors: XW
authors: Ye
authors: Xiao-jia
authors: XJ
authors: Huang
authors: Zhi-fang
authors: ZF
authors: Wu
mesh_terms: D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D008297:Male; D010309:Parotitis / Q000276:immunology*; D012008:Recurrence
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007073:Immunoglobulin E