title: Functional neuroimaging in the postictal state.
abstract: The postictal state is defined as manifestation of seizure-induced reversible alterations in neuronal function, but not structure. Following a seizure, it is common to experience feelings of exhaustion, both mental and physical, that can last a day or two. There are three major hypotheses regarding what cellular and molecular mechanisms could cause the observed postictal symptoms: neurotransmitter depletion or changes in receptor concentration, active inhibition, and cerebral blood flow changes. Here, we describe the contributions of functional neuroimaging studies to the understanding of postictal symptoms.
authors: Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK. mkoepp@ion.ucl.ac.uk
authors: Matthias J
authors: MJ
authors: Koepp
authors: Beate
authors: B
authors: Diehl
authors: Friedrich G
authors: FG
authors: Woermann
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D012640:Seizures / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015899:Tomography, Emission-Computed, Single-Photon