A case of fever of unknown origin: co-existence of Kikuchi-Fujimoto disease and acute disseminated encephalomyelitis (ADEM).
It is believed that viral infections and the hyperimmune reaction due to these infections are involved in the etiology of Kikuchi-Fujimoto Disease (KFD), a rare cause of fever of unknown origin. Axillary lymphadenopathy and neurologic involvement are rare in KFD. We present a patient diagnosed with KFD histopathologically during an investigation of the origin of fever and axillary lymphadenopathy. Subsequently, incidental sinus aspergilloma was diagnosed radiologically in the patient and acute disseminated encephalitis developed during follow-up. This report aims to draw attention to the co-existence of KFD and Acute Disseminated Encephalomyelitis, two diseases of which the origins are not clear.
Avkan-Oguz
Vildan
V
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylul University School of Medicine. vildan.oguz@gmail.com
Yapar
Nur
N
Ozakbas
Serkan
S
Demir-Onder
Kubra
K
Aktas
Eray
E
Alp-Cavus
Sema
S
Ozkal
Sermin
S
Men
Suleyman
S
Kargi
Aydanur
A
D000328:Adult; D004673:Encephalomyelitis, Acute Disseminated / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D005335:Fever of Unknown Origin / Q000175:diagnosis* / Q000209:etiology*; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000175:diagnosis*; D006801:Humans