title: [Per and post-natal medical management of congenital diaphragmatic hernia].
abstract: Congenital diaphragmatic hernia (CDH) is a 1 out of 3500 live-born malformation with persistent 30-40% mortality rate, related to severe pulmonary hypoplasia and hypertension. Better knowledge on the mechanisms inducing failure of adaptation at birth is a prerequisite for improving CDH prognosis. CDH is also associated with longterm morbidity, including prolonged respiratory failure, failure to growth, oral aversion, and scoliosis. Early prevention starting as soon as the first hours of life are required to reduced long term morbidity. The aims of the management are not only to reduce early mortality, related to persistent pulmonary hypertension, but also to prevent late morbidity.
authors: Site de Lille, Hôpital Jeanne de Flandre, CHRU de Lille. lstorme@chru-lille.fr
authors: L
authors: L
authors: Storme
authors: T
authors: T
authors: Pennaforte
authors: T
authors: T
authors: Rakza
authors: A
authors: A
authors: Fily
authors: R
authors: R
authors: Sfeir
authors: E
authors: E
authors: Aubry
authors: M
authors: M
authors: Bonnevalle
authors: P
authors: P
authors: Fayoux
authors: P
authors: P
authors: Deruelle
authors: V
authors: V
authors: Houfflin-Debarge
authors: P
authors: P
authors: Vaast
authors: M-H
authors: MH
authors: Depoortère
authors: B
authors: B
authors: Soulignac
authors: N
authors: N
authors: Norel
authors: R
authors: R
authors: Deuze
authors: A
authors: A
authors: Deschildre
authors: C
authors: C
authors: Thumerelle
authors: D
authors: D
authors: Guimber
authors: F
authors: F
authors: Gottrand
authors: A
authors: A
authors: Benachi
authors: P
authors: P
authors: De Lagausie
mesh_terms: D004066:Digestive System Diseases / Q000209:etiology / Q000517:prevention & control; D006548:Hernia, Diaphragmatic / Q000150:complications / Q000628:therapy; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy*; D012140:Respiratory Tract Diseases / Q000209:etiology / Q000517:prevention & control