title: Use of a nanocrystalline silver dressing and vacuum-assisted closure in a severely burned dog.
abstract: OBJECTIVE
  To describe the first veterinary use of a nanocrystalline silver dressing (NSD) and use of vacuum-assisted closure (VAC) to treat a severely burned dog.
  
  
  METHODS
  A 1-year-old female intact American Staffordshire Terrier with 50% total body surface area burned was referred for definitive care approximately 18-24 hours post injury. The dog was treated with crystalloid fluids, hydroxyethyl starch, and antimicrobials based on culture and sensitivity results of wound cultures, fresh frozen plasma, human serum albumin, and packed red cells. Wound care initially consisted of daily debridement under anesthesia with silver sulfadiazine application and bandaging. Because of the extent and the location of the wounds and morbid state of the patient, early wound grafting was not an option. Because of its reported improvement in granulation tissue formation and decreased tissue edema, VAC was used once the majority of burned tissue was manually debrided. Because of the pain caused by VAC and traditional bandaging techniques with this extent of injury, an NSD was utilized. This strategy was chosen due to the antimicrobial properties of NSD and the reduced necessity for daily bandage changes, which was reduced to only every 3 days. This protocol reduced the need for daily sedation or anesthesia.
  
  
  CONCLUSIONS
  VAC and NSD were used successfully for the treatment of a severe burn injury in a dog. The use of NSD decreased the cost of therapy by reducing the need for daily bandage changes, thereby reducing the anesthetic and analgesic costs and allowing the patient to be managed on an outpatient basis.
authors: Advanced Critical Care, City of Angels Veterinary Specialty Center, Culver City, CA 90232, USA. colleen_mullally@hotmail.com
authors: Colleen
authors: C
authors: Mullally
authors: Kim
authors: K
authors: Carey
authors: Ravi
authors: R
authors: Seshadri
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001458:Bandages / Q000662:veterinary; D002056:Burns / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D003646:Debridement / Q000662:veterinary; D004285:Dogs / Q000293:injuries* / Q000601:surgery; D005260:Female; D005390:Fires; D053758:Nanoparticles; D054843:Negative-Pressure Wound Therapy / Q000379:methods / Q000662:veterinary*; D012835:Silver Nitrate / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents; D012835:Silver Nitrate