title: Hyperhidrosis: evolving concepts and a comprehensive review.
abstract: Hyperhidrosis (primary or secondary) describes a disorder of excessive sweating. It has a significant negative impact on quality of life and affects nearly 1% of the population living in the United Kingdom (UK). Axillary involvement is the most common affecting 80% of cases. A common link to these disorders is an extreme non-thermoregulatory sympathetic stimulus of exocrine sweat glands, mostly due to emotional stimuli. Non-surgical treatment involves topical medication, iontophoresis and systemic anti-cholinergics. More recently the use of intradermal botulinum toxin has gained popularity. Surgical treatment reserved for severe cases, not responding to conservative management involves local excision, curettage and thoracoscopic sympathectomy. Evolving concepts for treatment, risks and benefits are discussed in the paper herein.
authors: Department of Thoracic, Cardiac and Vascular Surgery, University of Goettingen, Germany.
authors: Tobias
authors: T
authors: Vorkamp
authors: Fung Joon
authors: FJ
authors: Foo
authors: Sidra
authors: S
authors: Khan
authors: Jan D
authors: JD
authors: Schmitto
authors: Paul
authors: P
authors: Wilson
mesh_terms: D018726:Anti-Dyskinesia Agents / Q000008:administration & dosage; D001905:Botulinum Toxins / Q000008:administration & dosage; D006801:Humans; D006945:Hyperhidrosis / Q000503:physiopathology / Q000601:surgery*; D007478:Iontophoresis; D013562:Sympathectomy; D013906:Thoracoscopy
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins