Orientations of the Bacteroides fragilis capsular polysaccharide biosynthesis locus promoters during symbiosis and infection.
Orientations of the seven invertible polysaccharide biosynthesis locus promoters of Bacteroides fragilis were determined from bacteria grown in vitro, from feces of monoassociated and complex colonized mice, and from B. fragilis-induced murine abscesses. Bacteria grown in vivo have greater variability in orientation of polysaccharide locus promoters than culture-grown organisms.
Troy
Erin B
EB
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Carey
Vincent J
VJ
Kasper
Dennis L
DL
Comstock
Laurie E
LE
D000038:Abscess / Q000382:microbiology; D000818:Animals; D001431:Bacteriological Techniques; D001442:Bacteroides Infections / Q000382:microbiology*; D001441:Bacteroides fragilis / Q000235:genetics / Q000378:metabolism*; D005243:Feces / Q000382:microbiology; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology; D051379:Mice; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis* / Q000235:genetics; D011401:Promoter Regions, Genetic; D013559:Symbiosis
D011135:Polysaccharides, Bacterial