title: Conjugate addition of lithiated methyl pyridines to enones.
abstract: Preparatively useful conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is reported. Addition of 2-picoline to 3-penten-2-one led to a concise synthesis of the alkaloids (+/-)-senepodine G and (+/-)-cermizine C.
authors: Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA. taberdf@udel.edu
authors: Douglass F
authors: DF
authors: Taber
authors: Pengfei
authors: P
authors: Guo
authors: Michael T
authors: MT
authors: Pirnot
mesh_terms: D003517:Cyclopentanes / Q000737:chemistry*; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010847:Picolines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003517:Cyclopentanes; D006574:Heterocyclic Compounds, 2-Ring; D010847:Picolines; C518697:cermizine C; C518698:senepodine G; C530793:2-picoline