Modular blue fluorescent RNA sensors for label-free detection of target molecules.
A blue fluorescent RNA was applied to modular blue fluorescent RNA sensors, wherein a "recognition" event of the target molecule by the aptamer domain is transmitted through a "communication" module, to a "signaling" fluorescent RNA domain, which "lights up".
Furutani
Chika
C
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, 615-8510, Kyoto, Japan.
Shinomiya
Kazuki
K
Aoyama
Yasuhiro
Y
Yamada
Katsuhiro
K
Sando
Shinsuke
S
D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D006690:Bisbenzimidazole / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*
D005456:Fluorescent Dyes; D012313:RNA; D006690:Bisbenzimidazole