title: 12-Helix folding of cyclobutane beta-amino acid oligomers.
abstract: The hexamer and octamer of trans-2-aminocyclobutane carboxylic acid were prepared and their conformational preferences studied experimentally and using molecular modeling. All observations suggest a marked preference for the folding of these oligomers into a well-defined 12-helical conformation, in both solution and the solid state.
authors: Clermont Université, Université Blaise Pascal, Laboratoire SEESIB (UMR 6504 - CNRS), 24 avenue des Landais, 63177 Aubière cedex, France.
authors: Carlos
authors: C
authors: Fernandes
authors: Sophie
authors: S
authors: Faure
authors: Elisabeth
authors: E
authors: Pereira
authors: Vincent
authors: V
authors: Théry
authors: Valérie
authors: V
authors: Declerck
authors: Régis
authors: R
authors: Guillot
authors: David J
authors: DJ
authors: Aitken
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003503:Cyclobutanes / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D013237:Stereoisomerism
chemical_list: C542744:2-aminocyclobutanecarboxylic acid; D000596:Amino Acids; D002264:Carboxylic Acids; D003503:Cyclobutanes