title: mzML--a community standard for mass spectrometry data.
abstract: Mass spectrometry is a fundamental tool for discovery and analysis in the life sciences. With the rapid advances in mass spectrometry technology and methods, it has become imperative to provide a standard output format for mass spectrometry data that will facilitate data sharing and analysis. Initially, the efforts to develop a standard format for mass spectrometry data resulted in multiple formats, each designed with a different underlying philosophy. To resolve the issues associated with having multiple formats, vendors, researchers, and software developers convened under the banner of the HUPO PSI to develop a single standard. The new data format incorporated many of the desirable technical attributes from the previous data formats, while adding a number of improvements, including features such as a controlled vocabulary with validation tools to ensure consistent usage of the format, improved support for selected reaction monitoring data, and immediately available implementations to facilitate rapid adoption by the community. The resulting standard data format, mzML, is a well tested open-source format for mass spectrometer output files that can be readily utilized by the community and easily adapted for incremental advances in mass spectrometry technology.
authors: Department of Medical Protein Research, VIB, B-9000 Ghent, Belgium.
authors: Lennart
authors: L
authors: Martens
authors: Matthew
authors: M
authors: Chambers
authors: Marc
authors: M
authors: Sturm
authors: Darren
authors: D
authors: Kessner
authors: Fredrik
authors: F
authors: Levander
authors: Jim
authors: J
authors: Shofstahl
authors: Wilfred H
authors: WH
authors: Tang
authors: Andreas
authors: A
authors: Römpp
authors: Steffen
authors: S
authors: Neumann
authors: Angel D
authors: AD
authors: Pizarro
authors: Luisa
authors: L
authors: Montecchi-Palazzi
authors: Natalie
authors: N
authors: Tasman
authors: Mike
authors: M
authors: Coleman
authors: Florian
authors: F
authors: Reisinger
authors: Puneet
authors: P
authors: Souda
authors: Henning
authors: H
authors: Hermjakob
authors: Pierre-Alain
authors: PA
authors: Binz
authors: Eric W
authors: EW
authors: Deutsch
mesh_terms: D030562:Databases, Protein / Q000592:standards*; D013058:Mass Spectrometry / Q000379:methods* / Q000592:standards*; D012015:Reference Standards; D015203:Reproducibility of Results; D012984:Software / Q000592:standards*