[Analysis on neutralization antibody titer of Japanese B encephalitis virus in healthy population in Shaanxi province].
OBJECTIVE
To detect Japanese B Encephalitis virus (JEV) neutralization antibody (NA) titer and evaluate immunologic barrier, analyze the factor of affecting JEV NA titer, and provide the data for JE control.


METHODS
Cluster sampling was selected randomly in the region of high, middle, low JE incidence rate. To detect the NA of JEV by micro neutralization test.


RESULTS
The positive rate of JEV NA (and GMT) was 81.3% (1:27.84) in Ankang prefecture where JE incidence rate was high, 47.9% (1:7.41) in Baoji prefecture where JE incidence rate was middle, 24.1% (1:3.04) in Tongchuan prefecture where JE disease rate was low. There was the tendency that JEV NA titer increased with increasing age in the region of high JE disease rate, and there was not this tendency in the region of low JE incidence rate.


CONCLUSIONS
In shaanxi province, the children's JEV NA titer was low in the region of high JE incidence rate, and it is important to vaccinate JE vaccine for children. The adult's JEV NA titer was low in the region of low JE incidence rate. And it is important to control JE disease in adult groups.
Zhang
Shao-bai
SB
Shaanxi Provincial Center for Disease Control and Prevention, Xi' an 710061, Shanxi, China.
Li
Ping
P
Liu
Xi-zhen
XZ
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D057134:Antibodies, Neutralizing / Q000097:blood* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002681:China; D004664:Encephalitis Virus, Japanese / Q000276:immunology*; D004672:Encephalitis, Japanese / Q000097:blood* / Q000276:immunology; D005260:Female; D006304:Health Status; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D011159:Population Surveillance; D055815:Young Adult
D057134:Antibodies, Neutralizing