title: Comet assay in neonatal sepsis.
abstract: OBJECTIVE
  To determine whether the DNA damage detected using the Comet assay helps in the diagnosis of neonatal sepsis
  
  
  METHODS
  Sepsis was diagnosed, based on clinical findings, laboratory findings and positive culture results, in 24 of the 48 newborns who participated in the study. Hematological parameters, baseline demographic data and genotoxic evaluation were investigated.
  
  
  RESULTS
  There were no significant differences in hematological, demographic and genotoxic data between cases and controls.
  
  
  CONCLUSIONS
  The Comet assay proved to be ineffective in the diagnosis of neonatal sepsis.
authors: Laboratório de Imunologia e Mutagênese, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
authors: Natália C
authors: NC
authors: Carvalho
authors: Rozilda L
authors: RL
authors: de Souza
authors: Felipe
authors: F
authors: Dal-Pizzol
authors: Vanessa Moraes
authors: VM
authors: de Andrade
mesh_terms: D020552:Comet Assay; D004249:DNA Damage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012372:ROC Curve; D018805:Sepsis / Q000175:diagnosis* / Q000235:genetics