Organocatalytic diimide reduction of enamides in water.
Bridged flavinium organocatalysts have displayed efficacy in the diimide mediated reduction of enamides in aqueous conditions. This represents the first diimide reduction of an electron rich alkene and offers a clean alternative to the use of alkylating agents for N-alkylation.
Marsh
Barrie J
BJ
Department of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Heath
Emma L
EL
Carbery
David R
DR
D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D000478:Alkylation; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D004583:Electrons; D005415:Flavins / Q000737:chemistry*; D007094:Imides / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000473:Alkanes; D000475:Alkenes; D000577:Amides; D005415:Flavins; D007094:Imides; D014867:Water