[Dectective of serum di-n-butyl phthalate and di-2-ethylhexyl phthalate level in normal children].
OBJECTIVE
To study on the level of serum di-n-butyl phthalate (DBP), di-2-ethylhexyl phthalate (DEHP) in normal children by using gas chromatography.


METHODS
Gas chromatography method was established. DBP, DEHP in normal children were detected, and their reference level was calculated, DBP and DEHP level in different age and genders were analysed.


RESULTS
DBP could be detected in 110 serum samples from total 310 samples, and DEHP could be detected in 118 serum samples from the total 310 samples. The detected contrations of DBP range from non detectable to 0.98 ng/ml, P75 was 0.68 ng/ml, P95 was 0.75 ng/ml. There was no difference in the detection ratios between females and males, while baby group detection ratios was lower than other groups. The detected contrations of DEHP range from non detectable to 0.94 ng/ml, P75 was 0.67 ng/ml, P95 was 0.74 ng/ml. There was no difference in the detection ratios between females and males. While there was difference among age groups.


CONCLUSIONS
The study domonstrated that DBP and DEHP concentrations in normal children are very low. The refrence level of DBP was suggested as lower than 0.75 ng/ml, DHEP was suggested as lower than 0.74 ng/ml.
Qiao
Lili
L
Songjiang Centred Hospital, Shanghai 201600, China. qiaolili1976@163.com
Cai
Depei
D
Shen
Jianwei
J
Gu
Aiqin
A
D002648:Child; D002675:Child, Preschool; D002681:China; D002849:Chromatography, Gas; D003993:Dibutyl Phthalate / Q000097:blood*; D004051:Diethylhexyl Phthalate / Q000097:blood*; D052244:Endocrine Disruptors / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010968:Plasticizers / Q000032:analysis; D012016:Reference Values
D052244:Endocrine Disruptors; D010968:Plasticizers; D003993:Dibutyl Phthalate; D004051:Diethylhexyl Phthalate