Copper(I)-secondary diamine complex-catalyzed enantioselective conjugate boration of linear β,β-disubstituted enones.
A copper(I)-chiral secondary diamine (L-e) complex catalyzes an enantioselective conjugate boration of β,β-disubstituted enones in high yields and up to 99% ee. Product chiral tertiary organoboronates can be converted to enantiomerically enriched cross-aldol products between ketones without any racemization.
Chen
I-Hon
IH
Institute of Microbial Chemistry, Tokyo, Kamiosaki 3-14-23, Shinagawa-ku, Tokyo 141-0021, Japan.
Kanai
Motomu
M
Shibasaki
Masakatsu
M
D001896:Boron Compounds / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003959:Diamines / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D001896:Boron Compounds; D003959:Diamines; D003300:Copper