title: [Chorea revealing a polycytemia vera].
abstract: Neurological manifestations in polycytemia vera are common. However, chorea is an exceptionally revealing feature of this disease. We report a 78-year-old man who presented with headache and an abnormal movement disorder corresponding to chorea. Laboratory findings showed increased levels of hemoglobin at 20 g/dl and hematocrit at 62.3%. An elevated erythrocyte mass to twice the normal value demonstrated the absolute erythrocytosis. A JAK2 V617F gene mutation was identified. A diagnosis of polycytemia vera-associated chorea was obtained. Clinical and biological outcomes were favorable after therapeutic phlebotomy and treatment with hydroxyurea. We recommend a complete blood cell count in elderly patient presenting with chorea to eliminate a diagnosis of polycytemia vera.
authors: Service de médecine interne, hôpital La Rabta, 1007 Tunis, Tunisia. benghorbelimed@yahoo.com
authors: I
authors: I
authors: Ben Ghorbel
authors: T
authors: T
authors: Ben Salem
authors: M
authors: M
authors: Lamloum
authors: M
authors: M
authors: Khanfir
authors: A
authors: A
authors: Braham
authors: M
authors: M
authors: Miled
authors: N
authors: N
authors: Ben Romdhane
authors: M H
authors: MH
authors: Houman
mesh_terms: D000368:Aged; D002819:Chorea / Q000209:etiology*; D006801:Humans; D008297:Male; D011087:Polycythemia Vera / Q000150:complications* / Q000175:diagnosis*