A surprising new route to 4-nitro-3-phenylisoxazole.
A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.
Hopf
Henning
H
Institut für Organische Chemie, Technische Universität Braunschweig, Postfach 3329, D-38023 Braunschweig, Germany. h.hopf@tu-bs.de
Mourad
Aboul-Fetouh E
AF
Jones
Peter G
PG