Enhanced transrectal ultrasound modalities in the diagnosis of prostate cancer.
Standard grayscale transrectal ultrasound has a poor sensitivity for detection of prostate cancer. Saturation biopsy schemes have improved prostate cancer detection rates over standard template biopsy schemes, but carry additional morbidity and cost. Enhanced ultrasound modalities (EUM), including color and power Doppler, contrast-enhancement, harmonic and flash replenishment imaging, and elastography have demonstrated improved prostate cancer detection. EUM targeting areas with increased or abnormal vascularity or firmness for biopsy offer improved prostate cancer detection. EUM, detect prostate cancer more efficiently than standard ultrasound guided biopsies. These emerging technologies may potentially augment standard prostate biopsy in clinical practice.
Trabulsi
Edouard J
EJ
Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. Edouard.trabulsi@jefferson.edu
Sackett
Daniel
D
Gomella
Leonard G
LG
Halpern
Ethan J
EJ
D000230:Adenocarcinoma; D001707:Biopsy, Needle; D003287:Contrast Media; D054459:Elasticity Imaging Techniques; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000098:blood supply / Q000175:diagnosis / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color; D018084:Ultrasonography, Interventional
D003287:Contrast Media