title: Highly selective nickel-catalyzed three-component coupling of alkynes with enones and alkenyl boronic acids: a novel route to substituted 1,3-dienes.
abstract: A highly regio- and stereoselective nickel-catalyzed three-component coupling of alkynes with enones and alkenyl boronic acids to afford highly substituted 1,3-dienes is described. The reaction can also be extended to cyclization of enynes with coupling to alkenyl boronic acids. A possible reaction mechanism involving a five-membered nickelacycle as a key intermediate is proposed.
authors: Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.
authors: Chun-Ming
authors: CM
authors: Yang
authors: Masilamani
authors: M
authors: Jeganmohan
authors: Kanniyappan
authors: K
authors: Parthasarathy
authors: Chien-Hong
authors: CH
authors: Cheng