Reversible cerebral vasoconstriction syndrome associated with hormone therapy for intrauterine insemination.
BACKGROUND
Reversible cerebral vasoconstriction syndrome (RCVS) comprises a heterogeneous group of acute neurological diseases which are characterized by thunderclap headache and evidence of reversible multifocal constriction of cerebral arteries. A number of precipitating factors have been described in the literature, including recent childbirth and use of vasoactive substances.


METHODS
Here we present the case of a female patient with RCVS which occurred in the setting of hormonal ovarian stimulation for intrauterine insemination.


CONCLUSIONS
This case possibly contributes to the understanding of the pathophysiological mechanisms underlying reversible cerebral vasoconstriction.
Freilinger
T
T
Neurologische Klinik und Poliklinik, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany. tobias.freilinger@med.uni-muenchen.de
Schmidt
C
C
Duering
M
M
Linn
J
J
Straube
A
A
Peters
N
N
D000328:Adult; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D006063:Chorionic Gonadotropin / Q000009:adverse effects*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000009:adverse effects*; D051270:Headache Disorders, Primary / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D010062:Ovulation Induction / Q000009:adverse effects; D014661:Vasoconstriction / Q000187:drug effects*; D020301:Vasospasm, Intracranial / Q000139:chemically induced* / Q000473:pathology
D006063:Chorionic Gonadotropin; D005640:Follicle Stimulating Hormone