Environmental risk factors for psychopathology.
In the past all psychopathologies were viewed as caused by the environment. Later on case-control and family-based studies of major psychiatric disorders found genetic associations, but in many cases these findings did not survive replications. A gene-environment approach gave new hope for possible associations. Gene environment correlations emphasized that the relationship are bidirectional. However, recent meta-analyses raised doubts about the consistency of these findings as well. The review summarizes the current view on the environmental factors in the major psychopathologies.
Schlossberg
Karin
K
Child and Adolescent Psychiatry Division, Geha Mental Health Center, Petach Tikva, Israel.
Massler
Anda
A
Zalsman
Gil
G
D001008:Anxiety Disorders / Q000209:etiology / Q000235:genetics; D003865:Major Depressive Disorder / Q000209:etiology / Q000235:genetics; D006801:Humans; D008016:Life Change Events; D001523:Mental Disorders / Q000209:etiology* / Q000235:genetics; D011599:Psychopathology; D011618:Psychotic Disorders / Q000209:etiology / Q000235:genetics; D012307:Risk Factors; D012559:Schizophrenia / Q000209:etiology / Q000235:genetics; D013313:Stress Disorders, Post-Traumatic / Q000209:etiology / Q000235:genetics