Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on titanium substrates.
We report the creation of motif-based artificial proteins that bind to titanium surfaces and mediate the deposition of crystalline calcium phosphate. These proteins enabled in aqua surface modification of titanium materials having an intricate structure used in medical applications.
Tsuji
Toru
T
Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Oaki
Yuya
Y
Yoshinari
Masao
M
Kato
Takashi
T
Shiba
Kiyotaka
K
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D002130:Calcium Phosphates / Q000737:chemistry*; D008969:Molecular Sequence Data; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
D002130:Calcium Phosphates; D011506:Proteins; C022045:octacalcium phosphate; D014025:Titanium