title: A physicist at Woods Hole: introducing the image intensifier and image processing to cell biology.
abstract: In 1963, by invitation, particle physicist George Reynolds (Princeton University) brought an image intensifier to Woods Hole Marine Biological Laboratory. Together, he and a group of biologists began experimenting with the device as a way to create images of cells in low-light level situations, especially in the study of bioluminescence. In this paper I am interested in how the scientists, a physicist and biologists in collaboration, assessed, interpreted and presented the pictures that they created with the aid of image intensification. In particular, I consider the problem of 'noise' in the image. The paper ends with an example of how Reynolds and a biologist at Woods Hole contended with the presence of noise in images used for publication. Here is an example of how data is modified, that is, enhanced, to serve as scientific evidence. By presenting an early and simple case of the altered image I reveal one way scientists addressed the potentiality of presenting inappropriately modified data - a concern that has garnered much attention in the current age of digital imaging technologies.
authors: Department of Visual Studies, SUNY, Buffalo, USA. naa6@buffalo.edu
authors: Nancy
authors: N
authors: Anderson
mesh_terms: D003585:Cell Biology / Q000266:history* / Q000295:instrumentation; D004141:Dinoflagellida / Q000502:physiology; D049673:History, 20th Century; D049674:History, 21st Century; D007091:Image Processing, Computer-Assisted / Q000941:ethics / Q000266:history* / Q000295:instrumentation; D008164:Luminescent Proteins / Q000266:history; D010825:Physics / Q000266:history* / Q000295:instrumentation; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000379:methods; D014481:United States
chemical_list: D008164:Luminescent Proteins