[Screening of silent myocardial ischaemia by dobutamine stress echocardiography among type 2 diabetics at high cardiovascular risk in Senegal].
BACKGROUND
Diabetes is a major risk factor for coronary artery disease witch may develop insidiously. Several non-invasive methods are used to detect silent myocardial ischaemia, especially in diabetic patients at high cardiovascular risk. We project to screen, by dobutamine stress echocardiography, silent myocardial ischaemia in type 2 diabetics in Senegal.


METHODS
We randomly recruited in hospital in Senegal type 2 diabetics aged at least 40 years and a dobutamine stress echocardiography was performed in those selected according to the French Society of Cardiology and the French Language Association for the Study of Diabetes and Metabolic Diseases.


RESULTS
Dobutamine stress echocardiography was performed in 79 diabetics at high cardiovascular risk, including 56 women. The average age was 58.8±11.8 years. The exam was positive in 67.1% of cases (53/79), with a predominance of motion abnormalities in anterior territory (83%). Cardiovascular risk factors associated with positivity of test were microalbuminuria (p=0.0001), inactivity (p=0.0001), dyslipidemia (p=0.0002), arterial hypertension (p=0.001), smoking (0.003) and male sex (p=0.004).


CONCLUSIONS
In Africa, dobutamine stress echocardiography has the advantage of its accessibility and its feasibility. Early detection of silent myocardial ischaemia in diabetics at high risk could optimize their care.
Mbaye
A
A
Service de cardiologie, hôpital Général de Grand Yoff, Dakar, Sénégal. ambaye8@hotmail.com
Yaméogo
N V
NV
Ndiaye
M B
MB
Kane
A D
AD
Diack
B
B
Dioum
M
M
Hakim
R
R
Diagne
D
D
Kane
M
M
Diao
M
M
Diallo
A
A
Diop
S N
SN
Kane
A
A
D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000150:complications; D002316:Cardiotonic Agents; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging; D048909:Diabetes Complications / Q000000981:diagnostic imaging*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004280:Dobutamine; D050171:Dyslipidemias / Q000150:complications; D025401:Echocardiography, Stress; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008019:Life Style; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012675:Senegal; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects
D002316:Cardiotonic Agents; D004280:Dobutamine