title: Aerobic capacity of rats recovered from fetal malnutrition with a fructose-rich diet.
abstract: The objective of this study was to analyze the aerobic capacity, through the maximal lactate steady-state (MLSS) protocol, of rats subjected to fetal protein malnutrition and recovered with a fructose-rich diet. Pregnant adult Wistar rats that were fed a balanced (17% protein) diet or a low-protein (6% protein) diet were used. After birth, the offspring were distributed into groups according to diet until 60 days of age: balanced (B), balanced diet during the whole experimental period; balanced-fructose (BF), balanced diet until birth and fructose-rich diet (60% fructose) until 60 days; low protein-balanced (LB), low-protein diet until birth and balanced diet until 60 days; and low protein-fructose (LF), low protein diet until birth and fructose-rich diet until 60 days. It was verified that the fructose-rich diet reduced body growth, mainly in the BF group. There was no difference among the groups in the load corresponding to the MLSS (B, 7.5+/-0.5%; BF, 7.4+/-0.6%; LB, 7.7+/-0.4%; and LF, 7.7+/-0.6% relative to body weight). However, the BF group presented higher blood lactate concentrations (4.8+/-0.9 mmol.L(-1)) at 25 min in the load corresponding to the MLSS (B, 3.2+/-0.9 mmol.L(-1); LB, 3.4+/-0.9 mmol.L(-1); and LF, 3.2+/-1.0 mmol.L(-1)). Taken together, these results indicate that the ability of young rats to perform exercise was not altered by intrauterine malnutrition or a fructose-rich diet, although the high fructose intake after the balanced diet in utero increased blood lactate during swimming exercises in rats.
authors: Department of Physical Education, São Paulo State University (UNESP), Rio Claro-SP, Brazil. lucambri@yahoo.com.br
authors: Lucieli Teresa
authors: LT
authors: Cambri
authors: Rodrigo Augusto
authors: RA
authors: Dalia
authors: Carla
authors: C
authors: Ribeiro
authors: Maria Alice
authors: MA
authors: Rostom de Mello
mesh_terms: D000367:Age Factors; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D018753:Diet, Protein-Restricted / Q000009:adverse effects*; D004044:Dietary Proteins / Q000097:blood; D019422:Dietary Sucrose / Q000008:administration & dosage*; D004195:Disease Models, Animal; D017079:Exercise Tolerance; D005260:Female; D048070:Fetal Nutrition Disorders / Q000178:diet therapy* / Q000378:metabolism / Q000503:physiopathology; D006003:Glycogen / Q000378:metabolism; D007700:Kinetics; D019344:Lactic Acid / Q000097:blood; D008099:Liver / Q000378:metabolism; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011502:Protein-Energy Malnutrition / Q000178:diet therapy* / Q000378:metabolism / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D020127:Recovery of Function; D012709:Serum Albumin / Q000378:metabolism; D013550:Swimming
chemical_list: D001786:Blood Glucose; D004044:Dietary Proteins; D019422:Dietary Sucrose; D012709:Serum Albumin; D019344:Lactic Acid; D006003:Glycogen