9-Aminoacridine peptide derivatives as versatile reporter systems for use in fluorescence lifetime assays.
A novel long lifetime fluorescence reporter based on 9-aminoacridine was designed, the lifetime of which can be modulated in a defined manner when in proximity to a tryptophan residue enabling fluorescence lifetime based biochemical assays to be configured.
Maltman
Beatrice A
BA
Almac Sciences (Scotland), Elvingston Science Centre, By Gladsmuir, East Lothian, EH33 1EH, Scotland, UK.
Dunsmore
Colin J
CJ
Couturier
Sarah C M
SC
Tirnaveanu
Adina E
AE
Delbederi
Zoica
Z
McMordie
R Austin S
RA
Naredo
Gregorio
G
Ramage
Robert
R
Cotton
Graham
G
D000585:Aminacrine / Q000737:chemistry*; D001681:Biological Assay / Q000379:methods*; D005453:Fluorescence; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*
D010455:Peptides; D000585:Aminacrine