RTN3 and RTN4: Candidate modulators in vascular cell apoptosis and atherosclerosis.
The vascular cell apoptosis may play an important role in the development of atherosclerosis. Reticulons, the only molecular so far to participate in all three apoptosis signaling pathways, may be a novel player in the progress of AS. We presumes that reticulons may belong to the principle node of apoptosis pathway and be the candidate factor linking apoptosis and AS.
Chen
Yaqin
Y
Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
Zhao
Shuiping
S
Xiang
Rong
R
D017209:Apoptosis; D050197:Atherosclerosis / Q000378:metabolism* / Q000473:pathology*; D001808:Blood Vessels / Q000378:metabolism* / Q000473:pathology*; D002352:Carrier Proteins / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D009185:Myelin Proteins / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D000070798:Nogo Proteins
D002352:Carrier Proteins; D008565:Membrane Proteins; D009185:Myelin Proteins; D009419:Nerve Tissue Proteins; D000070798:Nogo Proteins; C476198:RTN3 protein, human; C000603199:RTN4 protein, human