Girls' preferences for HPV vaccination: a discrete choice experiment.
A discrete choice experiment was developed to investigate if girls aged 12-16 years make trade-offs between various aspects of human papillomavirus (HPV) vaccination, and to elicit the relative weight that girls' place on these characteristics. Degree of protection against cervical cancer, protection duration, risk of side-effects, and age of vaccination, all proved to influence girls' preferences for HPV vaccination. We found that girls were willing to trade-off 38% protection against cervical cancer to obtain a lifetime protection instead of a protection duration of 6 years, or 17% to obtain an HPV vaccination with a 1 per 750,000 instead of 1 per 150,000 risk of serious side-effects. We conclude that girls indeed made a trade-off between degree of protection and other vaccine characteristics, and that uptake of HPV vaccination may change considerably if girls are supplied with new evidence-based information about the degree of protection against cervical cancer, the protection duration, and the risk of serious side-effects.
de Bekker-Grob
Esther W
EW
Department of Public Health, Erasmus MC - University Medical Centre Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. e.debekker@erasmusmc.nl
Hofman
Robine
R
Donkers
Bas
B
van Ballegooijen
Marjolein
M
Helmerhorst
Theo J M
TJ
Raat
Hein
H
Korfage
Ida J
IJ
D000293:Adolescent; D002648:Child; D002755:Choice Behavior; D005260:Female; D006801:Humans; D009426:Netherlands; D030361:Papillomavirus Infections / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*; D057240:Patient Preference; D018570:Risk Assessment; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control
D053918:Papillomavirus Vaccines