Disease patterns and immune responses in the offspring to sows with high or low antibody levels to Actinobacillus pleuropneumoniae serotype 2.
The serum antibody responses to Actinobacillus pleuropneumoniae and the secondary invader Pasteurella multocida were monitored from birth until slaughter in the offspring to sows with high or low levels of serum antibodies to A. pleuropneumoniae. Serum antibody concentrations to A. pleuropneumoniae were higher from birth to the age of 9 weeks in piglets delivered by high responding sows. In contrast, antibody levels to P. multocida were similar in both groups during this period. From the age of 20 and 15 weeks, antibody levels to A. pleuropneumoniae and P. multocida, respectively, were higher in the offspring to high responding sows. This implies that the offspring to sows with high levels of antibodies may be better protected during the first period of life because of a higher level of passively derived immunity. These piglets will also mount a higher antibody response when later infected, indicating a heritability of the humoral immune response.
Sjölund
M
M
National Veterinary Institute, SE-751 89 Uppsala, Sweden; Swedish University of Agricultural Sciences, Dept. of Clinical Sciences, P.O. Box 7054, SE-750 07 Uppsala, Sweden. Electronic address: marie.sjolund@sva.se.
Zoric
M
M
National Veterinary Institute, SE-751 89 Uppsala, Sweden; Swedish University of Agricultural Sciences, Dept. of Clinical Sciences, P.O. Box 7054, SE-750 07 Uppsala, Sweden.
Persson
M
M
Swedish University of Agricultural Sciences, Dept. of Clinical Sciences, P.O. Box 7054, SE-750 07 Uppsala, Sweden.
Karlsson
G
G
Swedish Animal Health Service, P.O. Box 38, S-641 21 Katrineholm, Sweden.
Wallgren
P
P
National Veterinary Institute, SE-751 89 Uppsala, Sweden; Swedish University of Agricultural Sciences, Dept. of Clinical Sciences, P.O. Box 7054, SE-750 07 Uppsala, Sweden.
D000189:Actinobacillus Infections / Q000276:immunology / Q000662:veterinary*; D016977:Actinobacillus pleuropneumoniae / Q000145:classification / Q000276:immunology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D005260:Female; D010326:Pasteurella Infections / Q000276:immunology / Q000662:veterinary*; D016979:Pasteurella multocida / Q000276:immunology*; D010998:Pleurisy / Q000097:blood / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D012703:Serotyping / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000276:immunology*; D015430:Weight Gain
D000907:Antibodies, Bacterial