title: MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.
abstract: The design and features of a beamline control software system for macromolecular crystallography (MX) experiments developed at the European Synchrotron Radiation Facility (ESRF) are described. This system, MxCuBE, allows users to easily and simply interact with beamline hardware components and provides automated routines for common tasks in the operation of a synchrotron beamline dedicated to experiments in MX. Additional functionality is provided through intuitive interfaces that enable the assessment of the diffraction characteristics of samples, experiment planning, automatic data collection and the on-line collection and analysis of X-ray emission spectra. The software can be run in a tandem client-server mode that allows for remote control and relevant experimental parameters and results are automatically logged in a relational database, ISPyB. MxCuBE is modular, flexible and extensible and is currently deployed on eight macromolecular crystallography beamlines at the ESRF. Additionally, the software is installed at MAX-lab beamline I911-3 and at BESSY beamline BL14.1.
authors: European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble, France.
authors: José
authors: J
authors: Gabadinho
authors: Antonia
authors: A
authors: Beteva
authors: Matias
authors: M
authors: Guijarro
authors: Vicente
authors: V
authors: Rey-Bakaikoa
authors: Darren
authors: D
authors: Spruce
authors: Matthew W
authors: MW
authors: Bowler
authors: Sandor
authors: S
authors: Brockhauser
authors: David
authors: D
authors: Flot
authors: Elspeth J
authors: EJ
authors: Gordon
authors: David R
authors: DR
authors: Hall
authors: Bernard
authors: B
authors: Lavault
authors: Andrew A
authors: AA
authors: McCarthy
authors: Joanne
authors: J
authors: McCarthy
authors: Edward
authors: E
authors: Mitchell
authors: Stéphanie
authors: S
authors: Monaco
authors: Christoph
authors: C
authors: Mueller-Dieckmann
authors: Didier
authors: D
authors: Nurizzo
authors: Raimond B G
authors: RB
authors: Ravelli
authors: Xavier
authors: X
authors: Thibault
authors: Martin A
authors: MA
authors: Walsh
authors: Gordon A
authors: GA
authors: Leonard
authors: Sean M
authors: SM
authors: McSweeney
mesh_terms: D002265:Carboxylic Ester Hydrolases / Q000737:chemistry; D018360:Crystallography, X-Ray / Q000379:methods*; D016208:Databases, Factual; D046911:Macromolecular Substances / Q000737:chemistry; D012984:Software; D013052:Spectrometry, X-Ray Emission; D017356:Synchrotrons; D013820:Thermolysin / Q000737:chemistry
chemical_list: D046911:Macromolecular Substances; D002265:Carboxylic Ester Hydrolases; C070196:feruloyl esterase; D013820:Thermolysin