[Optimization of combination modes of medical materials in extract of Huanglian Jiedu decoction by semi-bionic extraction].
OBJECTIVE
To optimize the combination modes of medical materials in extract of Huanglian Jiedu decoction.


METHODS
Divided the medical materials of Huanglian Jiedu decotion into 15 groups and extracted by semi-bionic estraction (SBE), the contents of berberine, baicalin, geniposide, total alkaloid, total flavonoid, total integral calculus area of HPLC and extract of 1 000 were determined, standardized, weighted and evaluated, respectively.


RESULTS
The maximum evaluated value Y for the extracting technique was AD + BC.


CONCLUSIONS
The optimal combination mode of the perscription is that Rhizoma Coptidis and Fructus Gardeniae, Radix Scutellariae and Cortex Phellodendri Amurensis are decocted together respectively then the two decoctions are merged.
Dou
Jinming
J
Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
Sun
Xiumei
X
Zhang
Zhaowang
Z
Yu
Dingrong
D
Li
Chao
C
D039323:Coptis / Q000737:chemistry*; D004304:Dosage Forms; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000302:isolation & purification*; D032062:Gardenia / Q000737:chemistry*; D032102:Phellodendron / Q000737:chemistry*; D031364:Scutellaria baicalensis / Q000737:chemistry*
D004304:Dosage Forms; D004365:Drugs, Chinese Herbal; C494417:huanglian