title: Exhaled air temperature in children with bronchopulmonary dysplasia.
abstract: BACKGROUND
  Because they have similar functional and clinical profiles, bronchopulmonary dysplasia (BPD) survivors are often treated as asthmatic patients. In truth, very little is known about the possible biochemical and inflammatory mechanisms playing a part in BPD survivors' lungs. The aim of this study was to measure exhaled breath temperature in BPD survivors by comparison with asthmatic cases and healthy controls.
  
  
  METHODS
  Three groups of age-matched adolescents (n = 17 each), that is, BPD survivors (gestational ages <31 weeks, birth weights <1,500 g), asthmatic subjects and healthy controls, underwent exhaled breath temperature and exhaled nitric oxide measurements, and spirometry.
  
  
  RESULTS
  Exhaled breath temperature was significantly lower in the BPD survivors (26.72°C [25.11-27.57]) than in the asthmatic patients (29.60°C [29.20-30.02], P < 0.001), while no significant difference emerged by comparison with healthy controls (26.97°C [26.58-27.38]). Considering the whole study population, a significant correlation was found between exhaled breath temperatures and exhaled nitric oxide concentrations (R = 0.42, P = 0.004). Spirometry revealed an obstructive lung function pattern in both the asthmatic cases and the BPD survivors, with lower parameters in the latter.
  
  
  CONCLUSIONS
  Exhaled breath temperatures and exhaled nitric oxide concentrations are significantly lower in BPD survivors than in asthmatic cases, suggesting that different pathogenetic mechanisms characterize these two chronic obstructive lung diseases.
authors: Deptartment of Pediatrics, University of Padova, Padova, Italy.
authors: Silvia
authors: S
authors: Carraro
authors: Giorgio
authors: G
authors: Piacentini
authors: Marta
authors: M
authors: Lusiani
authors: Zeynep S
authors: ZS
authors: Uyan
authors: Marco
authors: M
authors: Filippone
authors: Maurizio
authors: M
authors: Schiavon
authors: Attilio L
authors: AL
authors: Boner
authors: Eugenio
authors: E
authors: Baraldi
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000503:physiopathology; D001831:Body Temperature / Q000502:physiology*; D001997:Bronchopulmonary Dysplasia / Q000503:physiopathology*; D016022:Case-Control Studies; D045853:Exhalation / Q000502:physiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008173:Lung Diseases, Obstructive / Q000175:diagnosis; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism; D012123:Pulmonary Ventilation / Q000502:physiology; D013147:Spirometry; D017741:Survivors
chemical_list: D009569:Nitric Oxide