[Anatomic and topographic lymphatic metastasis and sentinel lymph node mapping in early stage of cervical cancer patients'].
Biopsy of the sentinel lymph nodes is a method by which using a specific marking. Can be detected and examined lymph nodes that are first in the way of lymph drainage and metastasis. In some cases they give us information for the metastatic status of the whole lymph region. They are named sentinel. The conception of the sentinel lymph nodes is one of the most important and interesting achievements of the clinical oncology for the last ten years. According to her it is possible by removing and examining of one or a few lymph nodes to predict if there is or no tumor invasion in the regional lymph basin.


METHODS
In the prospective study for two years period are made in clinic of Oncogynecology, Oncologic center to University Hospital of Pleven. 129 cases with proved histological invasive cancer of the uterine cervix after making a clips--biopsy or separated curettage. We applied a preoperative method for detection of the sentinel lymph nodes by using a coloring agent to all the patients included and after that, they had a different kind of operative intervention on the uterine and the lymph nodes.


OBJECTIVE
Our aim was to show the locoregional metastasing and detection of the SLNB in patients with invasive cancer of the uterine cervix, by using a coloring agents Patent blau V (PV)--which passed through surgical intervention on the uterine and pelvic or paraaortic dissection. Our goal was to clear up the anatomic topographical lymph metastasing and coloring by levels and localization in invasive cancer of the uterine cervix--regionally in pelvic lymph nodes and in paraaortic area.


CONCLUSIONS
Sentinel lymph biopsy has its place in the detection of the lymph metastasis in cancer of the uterine cervix, and their localization shows the ways of lymph metastasis and this kind of gynecological tumors and gives an opportunity for an individual way of surgical treatment in patients with early cancer of the uterine cervix.
Chinkova
N
N
Tanchev
L
L
Strateva
D
D
Tsvetkov
Ch
Ch
Tsvetkov
Ch
Ch
Gorchev
G
G
D000328:Adult; D000368:Aged; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D002583:Uterine Cervical Neoplasms / Q000473:pathology*
D004396:Coloring Agents