title: Brønsted acid catalyzed asymmetric aldol reaction: a complementary approach to enamine catalysis.
abstract: A syn-enantioselective aldol reaction has been developed using Brønsted acid catalysis based on H(8)-BINOL-derived phosphoric acids. This method affords an efficient synthesis of various beta-hydroxy ketones, some of which could not be synthesized using enamine organocatalysis.
authors: Laboratoire de Chimie Moléculaire et Thio-organique, ENSICAEN, Université de Caen Basse-Normandie, CNRS, France.
authors: Guillaume
authors: G
authors: Pousse
authors: Fabien
authors: F
authors: Le Cavelier
authors: Luke
authors: L
authors: Humphreys
authors: Jacques
authors: J
authors: Rouden
authors: Jérôme
authors: J
authors: Blanchet
mesh_terms: D000546:Amanitins / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010756:Phosphoric Acids / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000546:Amanitins; D007659:Ketones; D010756:Phosphoric Acids; C049964:aldoamanitin