[Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides].
OBJECTIVE
To investigate the chemical constituents from the whole plants of Senecio chrysanthemoides.


METHODS
The chemical constituents were isolated and purified by chromatographic techniques over silica gel, Sephadex LH-20, preparative TLC and preparative HPLC. Structures of the compounds were identified by NMR and MS spectroscopic methods.


RESULTS
Twenty five compounds were obtained and their structures were elucidated as seneciphyline (1), senecionine (2) , 1,2-dihydrocacalohastine (3) , eu-desm-4( 15)-ene-1beta,6alpha-diol (4), 7,11,15-trimethyl- 3methylidenehexadecane-1,2-diol (5), faradiol 3-O-palmitate (6),maniladiol 3-O-palmitate (7), faradiol (8), maniladiol (9), beta-amyrin (10), alpha-amyrin (11), betulin (12), loranthol (13), (+)-syringaresinol (14) , 1-hydroxy-4-oxo-cyclohexane-1-acetate (15), 2, 6-dimethoxy-p-benzoquinone (16), stigmasta-5, 22-dien-3beta-hydroxy-7-one (17) , stigmasta-5, 22-dien-7-one (18) , stigmasta-4-en-3-one (19), stigmasta-4,22-dien-3-one (20), beta-sitosterol (21), stigmasterol (22), daucosterol (23), glycerol 1-hendecanoate (24), and methyl hendecanoate (25).


CONCLUSIONS
Compounds 5-9,13, 17-20 and 24 were obtained from the genus Senecio for the first time.
Lin
Sheng
S
College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Zhanf
Zhongxiao
Z
Shen
Yunheng
Y
Li
Huiliang
H
Shan
Lei
L
Liu
Runhui
R
Xu
Xike
X
Zhanf
Weidong
W
D000085:Acetates / Q000737:chemistry; D005591:Chemical Fractionation; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification; D012674:Senecio / Q000737:chemistry*
D000085:Acetates; D010936:Plant Extracts