Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152.
More than 2700 unrelated individuals from Europe, northern Africa and western Asia were analyzed for the marker M269, which defines the Y chromosome haplogroup R1b1b2. A total of 593 subjects belonging to this haplogroup were identified and further analyzed for two SNPs, U106 and U152, which define haplogroups R1b1b2g and R1b1b2h, respectively. These haplogroups showed quite different frequency distribution patterns within Europe, with frequency peaks in northern Europe (R1b1b2g) and northern Italy/France (R1b1b2h).
Cruciani
Fulvio
F
Dipartimento di Genetica e Biologia Molecolare, Sapienza Università di Roma, Rome, Italy.
Trombetta
Beniamino
B
Antonelli
Cheyenne
C
Pascone
Roberto
R
Valesini
Guido
G
Scalzi
Valentina
V
Vona
Giuseppe
G
Melegh
Bela
B
Zagradisnik
Boris
B
Assum
Guenter
G
Efremov
Georgi D
GD
Sellitto
Daniele
D
Scozzari
Rosaria
R
D041322:Chromosomes, Human, Y; D006239:Haplotypes; D006801:Humans; D020641:Polymorphism, Single Nucleotide