The postictal state: effects of age and underlying brain dysfunction.
There is relatively little information on the underlying parameters that affect clinical features of the postictal period. Age-related physiological changes, including alterations in cerebral blood flow and metabolism, neurotransmitter function, and responses of the brain to seizure activity may affect postictal clinical phenomena. Some conclusions can be drawn. Elderly adults and children, particularly in the presence of diffuse cerebral dysfunction, may have more prolonged postictal confusion. Postictal dysphasia strongly suggests a dominant hemisphere focus, more often temporal, and Todd's paralysis is always contralateral to the epileptogenic zone. Much additional information could be derived from the vast amount of video/EEG monitoring data available.
Theodore
William H
WH
Clinical Epilepsy Section, National Institutes of Health, Bethesda, MD 20892, USA. theodorw@ninds.nih.gov
D000328:Adult; D000367:Age Factors; D000368:Aged; D020324:Amnesia, Anterograde / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D001921:Brain / Q000378:metabolism / Q000503:physiopathology*; D002648:Child; D006801:Humans; D010243:Paralysis / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D012640:Seizures / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology*