[Consequences for the newborn of alcohol consumption during pregnancy].
BACKGROUND
This paper aims at showing the immediate and long-term consequences affecting newborns whose mothers did not reduce or stop their consumption of alcohol when they were pregnant; these women were chosen among women who also used psychoactive substances.


METHODS
A retrospective cohort was constituted of babies who were found to have been exposed in utero to one or more legal or illegal psychoactive substance(s) and who were born or hospitalized between 1999 and 2008 in a hospital near Paris. Among the cohort of 170 babies, 56 had mothers who had not modified their alcohol consumption when they were pregnant, 30 had mothers who had reduced their alcohol consumption, and 84 had mothers who declared having been abstinent.


RESULTS
The babies born to mothers who did not modify their alcohol consumption when pregnant were more likely to be premature (30%) and hospitalized in the neonatology hospital unit (60.7%). They needed specific care for durations significantly longer than the babies exposed in utero to other psychoactive substances (P<0.005). They were more often diagnosed with fetal alcohol spectrum disorders (18%) and placed in a foster family (18%).


CONCLUSIONS
Given the negative consequences on the babies born to mothers who do not modify their alcohol consumption when pregnant, these mothers should be identified and provided with better care. The successful strategies for early therapeutic interventions used in other countries should be studied as examples. This would make it possible to reduce the enormous financial, material and human costs that are a direct consequence of alcohol consumption during pregnancy.
Toutain
S
S
CERMES 3, équipe 2, Cesames université Paris Descartes, 45, rue des Saints-Pères 75270 Paris cedex 06, France. stephanie.toutain@parisdescartes.fr
Simmat-Durand
L
L
Crenn-Hébert
C
C
Simonpoli
A-M
AM
Vellut
N
N
Genest
L
L
Miossec
E
E
Lejeune
C
C
D000428:Alcohol Drinking / Q000009:adverse effects* / Q000191:economics / Q000517:prevention & control; D015331:Cohort Studies; D003376:Counseling / Q000379:methods; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000191:economics / Q000209:etiology*; D005317:Fetal Growth Retardation / Q000191:economics / Q000209:etiology*; D005602:France; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007902:Length of Stay / Q000191:economics; D009035:Mothers; D011247:Pregnancy; D012189:Retrospective Studies