title: Total synthesis of (+/-)-vertine with Z-selective RCM as a key step.
abstract: A concise total synthesis of the strained pentacyclic alkaloid (+/-)-Vertine has been achieved in eleven steps with the key steps being pelletierine condensation, Suzuki-Miyaura coupling, and ring-closing metathesis.
authors: Department of Organic Chemistry, University of Geneva, 30, quai Ernest Ansermet, CH-1211 Geneva, Switzerland.
authors: Laetitia
authors: L
authors: Chausset-Boissarie
authors: Roman
authors: R
authors: Arvai
authors: Graham R
authors: GR
authors: Cumming
authors: Céline
authors: C
authors: Besnard
authors: E Peter
authors: EP
authors: Kündig
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; C000519:cryogenine