[Role of immunologic abnormality in recurrent parotitis in children].
To investigate the relationship between immune function and the recurrent parotitis (RP) for children.



The children diagnosed as RP were divided into two groups: aged under 6y and over 6y and the immune function were measured and compared with that of normal children.



For RP children the ratio of CD4+ T cell in over 6y group was significantly lower than that in under 6y group (P<0.05), while IgG value in over 6y group was higher than that in under 6y group (P<0.05). Compared with normal children, RP children in under 6y group had higher CD8+ T cell ratio and IgG, IgE, IgA and C3 value (P<0.01) and lower CD4+ T cell ratio (P<0.01), while RP children over 6y group, they had higher CD8+ T cell ratio, IgE value (P<0.01) and C3 (P<0.05), lower CD4<T cell ratio than those in control group (P<0.01). IgE value and CD8+ T cell ratio in under 6y group were higher than those over 6y control group (P<0.01).



Impaired immune function may play an important role in the recurrent parotitis in children.
Yuan
Wen-hua
WH
Department of Stomatology, The Affiliated Children's Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. ruanwh@hzcnc.com
Su
Ji-mei
JM
Ye
Xiao-wei
XW
Huang
Xiao-jia
XJ
Wu
Zhi-fang
ZF
D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D008297:Male; D010309:Parotitis / Q000276:immunology*; D012008:Recurrence
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007073:Immunoglobulin E