Liposomal contrast agents in brain tumor imaging.
Treatment of glioblastoma multiforme remains a major challenge despite advances in standard therapy, including surgery, radiation, and chemotherapy. The field of nanomedicine is expected to have a major impact on the treatment and management of brain tumors. Over the past decade, significant efforts have been made in using nanoparticles for diagnosis and treatment of brain tumors. One class of nanoparticles, liposomes, have received considerable attention for use as nanocarriers for delivery of therapeutics and contrast agents. The purpose of this article is to present the advances in the design and functional characteristics of liposomes for applications in brain tumor imaging.
Ghaghada
Ketan B
KB
School of Health Information Sciences, The University of Texas Health Science Center at Houston, 7000 Fannin Street, Suite 600, Houston, TX 77030, USA.
Colen
Rivka R
RR
Hawley
Catherine R
CR
Patel
Neil
N
Mukundan
Srinivasan
S
D001932:Brain Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008081:Liposomes; D008279:Magnetic Resonance Imaging / Q000379:methods*
D003287:Contrast Media; D008081:Liposomes