[A case of Down's syndrome associated with recurrent testicular tumor treated by chemotherapy successfully: review of 41 cases in Japanese literature].
A 35-year-old male patient with Down' s syndrome received radical inguinal orchitectomy for left testicular tumor in 2006. Histological examination revealed a typical seminoma. 18 months after the operation, we found a metastasis in the right retroperitoneum lymph node. He received adjuvant chemotherapy (bleomycin, etoposide, and cisplatin : BEP). After 3 cycles of chemotherapy, the tumor disappeared. There is no obvious re-occurrence sign and general condition is good after chemotherapy. As we treated a relapse of seminoma in Down's syndrome successfully, we report this case and review 41 cases in Japanese literatures.
Yoneda
Suguru
S
The Department of Urology, Osaka General Medical Center, Osaka, Japan.
Nakazawa
Shigeaki
S
Takezawa
Kentaro
K
Kato
Taigo
T
Tanigawa
Go
G
Fujita
Kazutoshi
K
Okumi
Masayoshi
M
Hosomi
Masahiro
M
Fushimi
Hiroaki
H
Yamaguchi
Seiji
S
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D004314:Down Syndrome / Q000150:complications*; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D018239:Seminoma / Q000150:complications* / Q000188:drug therapy*; D013736:Testicular Neoplasms / Q000150:complications* / Q000188:drug therapy*
D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin