[A case of rectal cancer combined with intraperitoneal abscess responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy].
The patient was a 55-year-old man who complained of lower abdominal pain and fever, and was admitted to an emergency clinic. His diagnosis was rectal perforation combined with intraperitoneal abscess. Because his condition was in the preseptic state, an emergency operation was performed for colostomy and abscess drainage. After operation, he was diagnosed with rectal cancer colonoscopically. He refused reoperation and selected an oral chemotherapy regimen (UFT+LV therapy). 18 months later, he underwent Hartmann's operation. Histologically, cancer cells were absent. Complete response to chemotherapy was confirmed. He is free from any sign of recurrence until now.
Yamada
Kyouji
K
Dept. of Gastroenterological and General Surgery, St. Marianna University School of Medicine.
Narabashi
Kiyoshi
K
Onoda
Keiichirou
K
Honda
Akeri
A
Hojyo
Koudai
K
Kawashima
Hatsuya
H
Hamaya
Masahiro
M
Okamoto
Norihiko
N
Noda
Shinichiro
S
Kaneko
Hideaki
H
Yokote
Kunio
K
D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003125:Colostomy; D003131:Combined Modality Therapy; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014498:Uracil / Q000008:administration & dosage / Q000627:therapeutic use
D005641:Tegafur; D014498:Uracil; D002955:Leucovorin