Response assessment of hormonal therapy in prostate cancer by [11C] choline PET/CT.
A 57-year-old man with an adenocarcinoma of the prostate, presented with multiple lymph nodes in the para-aortic and right iliac region on computer tomography (CT). However, since the radiologic images were taken 3 weeks following an urosepsis, the differentiation between inflamed and metastatic lymph nodes is difficult. Thus, an integrated [C] choline positron emission tomography and computer tomography (PET/CT) was performed, showing multiple lymph nodes. The patient was staged as cT3N1M0 and treated with hormonal therapy. The choline PET/CT performed after hormonal treatment showed no more hypermetabolic lymph nodes. This case substantiate the hypothesis that choline PET/CT could be used to evaluate therapy response in prostate cancer patients.
De Waele
Alexandra
A
Department of Nuclear Medicine, UZ Leuven-Gasthuisberg, Leuven, Belgium. alexandradewaele@hotmail.com
Van Binnebeek
Sofie
S
Mottaghy
Felix M
FM
D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002250:Carbon Radioisotopes; D002794:Choline; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D018931:Antineoplastic Agents, Hormonal; D002250:Carbon Radioisotopes; D002794:Choline