title: TWENTE Study: The Real-World Endeavor Resolute Versus Xience V Drug-Eluting Stent Study in Twente: study design, rationale and objectives.
abstract: Background. New-generation drug-eluting stents (DES) may solve several problems encountered with first-generation DES, but there is a lack of prospective head-to-head comparisons between new-generation DES. In addition, the outcome of regulatory trials may not perfectly reflect the outcome in 'real world' patients.Objectives. To compare the efficacy and safety of two new-generation DES in a 'real world' patient population.Methods. A prospective, randomised, single-blinded clinical trial to evaluate clinical outcome after Endeavor Resolute vs. Xience V stent implantation. The primary endpoint is target vessel failure at one-year follow-up. In addition, the study comprises a two-year and an open-label five-year follow-up. (Neth Heart J 2010;18:360-4.).
authors: Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, the Netherlands.
authors: M W Z
authors: MW
authors: Basalus
authors: K
authors: K
authors: Tandjung
authors: K G
authors: KG
authors: van Houwelingen
authors: M G
authors: MG
authors: Stoel
authors: F H A F
authors: FH
authors: de Man
authors: J W
authors: JW
authors: Louwerenburg
authors: S A M
authors: SA
authors: Saïd
authors: G C M
authors: GC
authors: Linssen
authors: M A W J
authors: MA
authors: Kleijne
authors: J
authors: J
authors: van der Palen
authors: J
authors: J
authors: Huisman
authors: P M J
authors: PM
authors: Verhorst
authors: C
authors: C
authors: von Birgelen