Science to practice: can CT be performed for multicolor molecular imaging?
In an animal model of atherosclerosis, it was shown that multispectral computed tomography (CT) used with two radiologic contrast agents (gold and iodine) can depict macrophages, vascularization, and calcification separately and simultaneously during only one scanning examination.
Bulte
Jeff W M
JW
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. jwmbulte@mri.jhu.edu
D000818:Animals; D050197:Atherosclerosis / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging; D003116:Color; D003287:Contrast Media; D004195:Disease Models, Animal; D004655:Emulsions; D006046:Gold; D006801:Humans; D007455:Iodine; D008264:Macrophages / Q000000981:diagnostic imaging; D051379:Mice; D018345:Mice, Knockout; D053758:Nanoparticles; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003287:Contrast Media; D004655:Emulsions; D006046:Gold; D007455:Iodine