title: Strategy of aortic root enlargement in patients undergoing aortic and mitral valve replacement.
abstract: BACKGROUND
  This study was undertaken to evaluate the strategy and validity of aortic root enlargement in patients undergoing aortic and mitral valve replacement.
  
  
  METHODS
  Between January 1999 and December 2008, 78 consecutive patients aged 38.5 +/- 9.4 years underwent aortic root enlargement and double valve replacement at our hospital. The body surface area was 1.4 +/- 0.18 m(2), the aortic annulus diameter was 18.26 +/- 1.34 mm, the aortic orifice area was 0.83 +/- 0.43 cm(2), and the mean aortic transvalvular pressure gradient was 47.5 +/- 35.6 mm Hg. The aortic root enlargement was performed using a Dacron patch lined with autologous pericardium on the basis of either the Nuñez (n = 36) or Manouguian (n = 42) procedure depending on how narrow the aortic root was.
  
  
  RESULTS
  Mechanical prostheses were implanted in all patients. The mean size of the aortic and mitral valves were 20.5 mm and 25.9 mm, respectively. The postoperative mean indexed effective orifice areas of the aortic and mitral valves were 1.13 +/- 0.14 cm(2)/m(2) and 1.56 +/- 0.17 cm(2)/m(2) (p < 0.01 compared with those preoperatively), respectively. The postoperative mean aortic and mitral transvalvular pressure gradients were 10.7 +/- 2.3 mm Hg and 3.7 +/- 1.6 mm Hg (p < 0.01 compared with those preoperatively), respectively. There were no reoperations for bleeding and no heart block. Valve-related complications included thromboembolism, cerebral hemorrhage, perivalvular leakage, and reoperation. There were 2 deaths, 1 early and 1 late, and survival at 1, 5, and 10 years was 98.7%, 97.4%, and 97.4%, respectively.
  
  
  CONCLUSIONS
  Aortic root enlargement in patients undergoing double valve replacement can be performed safely to avoid postoperative aortic prosthesis-patient mismatch.
authors: Department of Cardiac Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
authors: Qianjin
authors: Q
authors: Zhong
authors: Yingbin
authors: Y
authors: Xiao
authors: Jinjin
authors: J
authors: Chen
authors: Ruiyan
authors: R
authors: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D001021:Aortic Valve / Q000033:anatomy & histology / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D055815:Young Adult