Polymorphisms and allele frequencies of the ABO blood group gene among the Jomon, Epi-Jomon and Okhotsk people in Hokkaido, northern Japan, revealed by ancient DNA analysis.
To investigate the genetic characteristics of the ancient populations of Hokkaido, northern Japan, polymorphisms of the ABO blood group gene were analyzed for 17 Jomon/Epi-Jomon specimens and 15 Okhotsk specimens using amplified product-length polymorphism and restriction fragment length polymorphism analyses. Five ABO alleles were identified from the Jomon/ Epi-Jomon and Okhotsk people. Allele frequencies of the Jomon/Epi-Jomon and Okhotsk people were compared with those of the modern Asian, European and Oceanic populations. The genetic relationships inferred from principal component analyses indicated that both Jomon/Epi-Jomon and Okhotsk people are included in the same group as modern Asian populations. However, the genetic characteristics of these ancient populations in Hokkaido were significantly different from each other, which is in agreement with the conclusions from mitochondrial DNA and ABCC11 gene analyses that were previously reported.
Sato
Takehiro
T
Graduate School of Science, Hokkaido University, Sapporo, Japan.
Kazuta
Hisako
H
Amano
Tetsuya
T
Ono
Hiroko
H
Ishida
Hajime
H
Kodera
Haruto
H
Matsumura
Hirofumi
H
Yoneda
Minoru
M
Dodo
Yukio
Y
Masuda
Ryuichi
R
D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D001106:Archaeology; D044466:Asian People / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D049690:History, Ancient; D006801:Humans; D007564:Japan; D011110:Polymorphism, Genetic; D025341:Principal Component Analysis
D000017:ABO Blood-Group System