Well-defined thermo-responsive polymeric nanocapsules by a one-pot method via surface-initiated atom transfer radical copolymerisation.
The well-defined thermo-responsive polymeric nanocapsules were prepared by the one-pot approach via the surface-initiated atom transfer radical copolymerisation of N-isopropyl acrylamide (NIPAM) and N, N-methylenebisacylamide (MBA) from the silica nanoparticle templates after the silica templates were removed by hydrofluoric acid (HF). The diameter of the polymeric nanocapsules is in the range of 20-40 nm, characterised by transmission electron microscopy (TEM). The temperature-induced dimensional change of the thermo-responsive polymeric nanocapsules was investigated by dynamic light scattering (DLS) in aqueous solutions. The intelligent thermo-responsive polymeric nanocapsules are expected to be used for the controlled release of sensitive molecules, such as enzymes, proteins or DNA, by changing the environmental temperature.
Du
P
P
Lanzhou University, State Key Laboratory of Applied Organic Chemistry and Institute of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Lanzhou, People's Republic of China.
Mu
B
B
Shen
R
R
Liu
P
P
D003692:Delayed-Action Preparations / Q000138:chemical synthesis*; D004339:Drug Compounding / Q000379:methods; D005609:Free Radicals; D006358:Hot Temperature; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties
D003692:Delayed-Action Preparations; D005609:Free Radicals; D053769:Nanocapsules; D011108:Polymers