Pickering-type water-in-oil-in-water multiple emulsions toward multihollow nanocomposite microspheres.
Multihollow hydroxyapatite (HAp)/poly(L-lactic acid) (PLLA) nanocomposite microspheres were readily fabricated by solvent evaporation from a "Pickering-type" water-in-(dichloromethane solution of PLLA)-in-water multiple emulsion stabilized with HAp nanoparticles. The multiple emulsion was stabilized with the aid of PLLA molecules used as a wettability modifier for HAp nanoparticles, although HAp nanoparticles did not work solely as particulate emulsifiers for Pickering-type emulsions consisting of pure dichloromethane and water. The interaction between PLLA and HAp nanoparticles at the oil-water interfaces plays a crucial role toward the preparation of stable multiple emulsion and multihollow microspheres.
Maeda
Hayata
H
Department of Applied Chemistry, Osaka Institute of Technology, 5-16-1 Ohmiya, Asahi-ku, Osaka 535-8585, Japan.
Okada
Masahiro
M
Fujii
Syuji
S
Nakamura
Yoshinobu
Y
Furuzono
Tsutomu
T
D017886:Durapatite / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry; D019344:Lactic Acid / Q000737:chemistry*; D008863:Microspheres; D053758:Nanoparticles / Q000737:chemistry*; D009821:Oils / Q000737:chemistry*; D010316:Particle Size; D011091:Polyesters; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties; D014867:Water / Q000737:chemistry*; D017155:Wettability
D004655:Emulsions; D009821:Oils; D011091:Polyesters; D011108:Polymers; D014867:Water; D019344:Lactic Acid; C033616:poly(lactide); D017886:Durapatite