[Free radical processes at patients with pathologies of biliary ducts and methods of their correction].
The main objective of a research in the early diagnostics of a functional condition of a liver, is to estimate the degree of the level of its expressiveness and timely pathogenetic correction on the basis of the free radical system processes of studying of patients with mechanical jaundice. Results were carried out among 61 patients with pathologies of bile tracts( biliary ducts) which proved the essential role of free radical processes with strengthening of peroxidation of membrane lipids against the absolute or relative insufficiency of endogenic antioxidants in the mechanism of development of hepatic insufficiency at the given category of patients with the highest degree expressed at the serious conditions of the patients with malignant diseases. It is revealed that the inclusion of energy corrector antioxidants of reamberin to the therapy as a part of standard schemes of treatment promoted positive regressing dynamics of parameters of free radical processes that are correlated with positive clinical symptoms and outcome of diseases.
Bolevich
S B
SB
Stupin
V A
VA
Gakhramanov
T V
TV
Khokonov
M A
MA
Silina
E V
EV
Men'shova
N I
NI
Bogdanova
L S
LS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000627:therapeutic use*; D005260:Female; D005609:Free Radicals / Q000378:metabolism*; D006801:Humans; D041781:Jaundice, Obstructive / Q000150:complications* / Q000188:drug therapy* / Q000378:metabolism; D015227:Lipid Peroxidation; D017093:Liver Failure / Q000188:drug therapy* / Q000209:etiology* / Q000378:metabolism; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D018384:Oxidative Stress; D013386:Succinates / Q000627:therapeutic use*
D000975:Antioxidants; D005609:Free Radicals; C549374:Reamberin; D013386:Succinates; D008536:Meglumine