[Effect of quercetin on the expression and growth of caspase-3 in lung adenocarcinoma cancer cell line A549.].
BACKGROUND
To study the influence of Quercetin in the expression of caspase-3 in Lung Adenocarcinoma Cancer cell line A549.


METHODS
The mRNA expression of caspase-3 in A549 Cells was detected by RT-PCR , and the protein expression was detected by Western blot.


RESULTS
The mRNA and protein expressions of caspase-3 was enhanced by Quercetin in dose- and time-dependent manners.


CONCLUSIONS
The enhancement effects of Quercetin on caspase-3 in A549 cells may provide promising therapy of tumor.
Wen
Chunsheng
C
Department of Respiratory Medicine,West China Hospital, Sichuan University, Chengdu,Sichuan 610041, China.
Ying
Binwu
B
Zhang
Yonggang
Y
Zhang
Jie
J
Fan
Hong
H