Paraneoplastic dermatoses associated with gynecologic and breast malignancies.
Paraneoplastic dermatoses are a heterogeneous group of skin disorders that manifest an underlying internal malignancy. Early recognition of these cutaneous hallmarks offers an opportunity for early diagnosis, treatment of the internal malignancy and monitoring for tumor recurrence. The 9 most common paraneoplastic and metastatic cutaneous manifestations of malignancies found in women with gynecologic or breast disease are reviewed including a review of multicentric reticulohistiocytosis, dermatomyositis, malignant acanthosis nigricans, erythema gyratum repens, hypertrichosis lanuginosa acquisita, Sweet syndrome, Paget disease, extramammary Paget disease, and Sister Mary Joseph nodule.


BACKGROUND
General obstetricians & gynecologists, reproductive endocrinology & infertility specialists, radiologists.


OBJECTIVE
After completion of this educational activity, the participant should be better able to identify cutaneous manifestations of gynecologic malignancies, evaluate patients with a thorough workup to screen those who have dermatoses suggestive of malignancy and assess patients with malignancy for the opportunity of early diagnosis and appropriate treatment.
Levine
Danielle
D
Department of Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA.
Miller
Sheryl
S
Al-Dawsari
Najla
N
Barak
Orr
O
Gottlieb
Alice B
AB
D001943:Breast Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D003882:Dermatomyositis / Q000209:etiology* / Q000473:pathology; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology