title: Synthesis, Structure, and Antiproliferative Activity of Three Gallium(III) Azole Complexes.
abstract: As part of our interest into the bioinorganic chemistry of gallium, gallium(III) complexes of the azole ligands 2,1,3-benzothiadiazole (btd), 1,2,3-benzotriazole (btaH), and 1-methyl-4,5-diphenylimidazole (L) have been isolated. Reaction of btaH or btd with GaBr(3) or GaCl(3) resulted in the mononuclear complexes [GaBr(3)(btaH)(2)] (1) and [GaCl(3)(btd)(2)] (2), respectively, while treatment of GaCl(3) with L resulted in the anionic complex (LH)(2)[GaCl(4)] (3). All three complexes were characterized by single-crystal X-ray crystallography and IR spectroscopy, while their antiproliferative activities were investigated against a series of human and mouse cancer cell lines.
authors: Department of Chemistry, University of Patras, 265 04 Patras, Greece.
authors: Stergios
authors: S
authors: Zanias
authors: Giannis S
authors: GS
authors: Papaefstathiou
authors: Catherine P
authors: CP
authors: Raptopoulou
authors: Konstantinos T
authors: KT
authors: Papazisis
authors: Vasiliki
authors: V
authors: Vala
authors: Dimitra
authors: D
authors: Zambouli
authors: Alexandros H
authors: AH
authors: Kortsaris
authors: Dimitrios A
authors: DA
authors: Kyriakidis
authors: Theodoros F
authors: TF
authors: Zafiropoulos