title: Biodistribution of technetium-99m pertechnetate after total colectomy in rats.
abstract: This study evaluated the effects of total colectomy on the biodistribution of technetium-99m pertechnetate ((99m)TcO(4)(-)) on the 28th postoperative day in rats. Samples of several organs were harvested for counting the percent of injected radioactivity/g of tissue (%ATI/g). The %ATI/g in colectomy rats was higher in the stomach and ileum than in sham and controls (p<0.05). Increase in mucosa and muscularis size of ileum was observed. Colectomy was associated with lower biodistribution in bladder and thyroid, T3, and T4, than in controls.
authors: Postgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Ave. Miguel Alcides Araújo 1889, Natal-RN 59078-270, Brazil.
authors: Amália Cínthia Meneses
authors: AC
authors: Rêgo
authors: Rachel Alcântara Oliveira
authors: RA
authors: Ramalho
authors: Eryvaldo Sócrates Tabosa
authors: ES
authors: Egito
authors: Irami
authors: I
authors: Araújo-Filho
authors: Italo Medeiros
authors: IM
authors: Azevedo
authors: Christopher J
authors: CJ
authors: Palestro
authors: Aldo Cunha
authors: AC
authors: Medeiros
mesh_terms: D000818:Animals; D001835:Body Weight; D003082:Colectomy; D051381:Rats; D017208:Rats, Wistar; D013670:Sodium Pertechnetate Tc 99m / Q000493:pharmacokinetics*; D014018:Tissue Distribution
chemical_list: D013670:Sodium Pertechnetate Tc 99m