[Recognition mechanism of supramolecular systems of beta-cyclodextrin derivatives and applications in chiral separation].
Beta-cyclodextrin (beta-CD) has the cavity in which the exterior is relatively hydrophilic and the interior is relatively lipophilic and multi-hydroxyl groups on it. So beta-CD can be modified by different substituent groups and form supramolecular systems with guests, and are applied to many fields. Recognition mechanism of beta-CD derivatives supramolecular systems is reviewed herein. Effects of structures of host and guest, solvent, buffer pH and linkage styles of stationary phase and study methods of ultraviolet-visible, fluorescence spectroscopy, circular dichroism spectrum, nuclear magnetic resonance, thermodynamics, X-ray and molecular dynamics simulation on mechanism are expounded. The applications in chiral separation are also introduced. This might lay a foundation for studying the general law of recognition mechanism.
Li
Xia
X
School of Chemical Engineering & Environment, Beijing Institute of Technology, Beijing 100081, China.
Zhou
Zhiming
Z
Meng
Zihui
Z