[New data on the efficacy of proton pump inhibitors in upper gastrointestinal bleeding].
Gastric pH should be maintained at very high values to prevent peptic ulcer rebleeding. A recent randomized trial, however, has confirmed that intravenous infusion of esomeprazole decreases the rebleeding rate after endoscopic therapy. In addition, the use of proton pump inhibitor perfusion at admission before diagnostic endoscopy reduces the need for endoscopic therapy and shortens the mean length of hospital stay.
Calvet
Xavier
X
Hospital de Sabadell, Institut Universitari Parc Taulí, Departament de Medicina, Universitat Autònoma de Barcelona, España. xcalvet@tauli.cat
D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy*; D006801:Humans; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
D054328:Proton Pump Inhibitors