title: Influence of acid etching on hydrogen peroxide diffusion through human dentin.
abstract: OBJECTIVE
  To evaluate the influence of dentin etching with phosphoric acid on hydrogen peroxide diffusion through human dentin in internal bleaching.
  
  
  METHODS
  46 human premolars were extracted for orthodontic reasons from adolescents. The teeth were endodontically treated and a flat defect was created at the enamel-cementum junction. The teeth were divided into two groups: the access cavity was etched for 30 seconds with 35% H3PO4 in the first group and left intact in the second group. The teeth were filled with 20 microL of 35% hydrogen peroxide gel. The receiving medium on the other side was renewed at Day 1, Day 2 and Day 7 to quantify the diffusing hydrogen peroxide. An analysis of variance was performed to compare the diffusion between the two groups.
  
  
  RESULTS
  This work demonstrated a higher hydrogen peroxide diffusion when the access cavity was etched (P < 0.01).
authors: Laboratory IMEB, Faculty of Odontology, Université de la Méditerranée, Marseille, France. Jcamps2035@aol.com
authors: Jean
authors: J
authors: Camps
authors: Ludovic
authors: L
authors: Pommel
authors: Virginie
authors: V
authors: Aubut
authors: Imad
authors: I
authors: About
mesh_terms: D000134:Acid Etching, Dental; D000704:Analysis of Variance; D001641:Bicuspid; D003804:Dentin / Q000378:metabolism*; D003806:Dentin Permeability; D004058:Diffusion; D006801:Humans; D006861:Hydrogen Peroxide / Q000493:pharmacokinetics*; D016014:Linear Models; D016877:Oxidants / Q000493:pharmacokinetics*; D010756:Phosphoric Acids; D014073:Tooth Bleaching / Q000379:methods*; D019553:Tooth, Nonvital
chemical_list: D016877:Oxidants; D010756:Phosphoric Acids; D006861:Hydrogen Peroxide; C030242:phosphoric acid