A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2'-deoxyadenosine affords a novel class of fluorescent analogues.
Novel rigid 8-biaryl-2'-deoxyadenosines with tuneable fluorescent properties can be accessed by an efficient sequential catalytic Pd(0)-coupling approach.
Storr
Thomas E
TE
Department of Chemistry, University of York, York, YO10 5DD, UK.
Strohmeier
Johanna A
JA
Baumann
Christoph G
CG
Fairlamb
Ian J S
IJ
D018360:Crystallography, X-Ray; D003839:Deoxyadenosines / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008968:Molecular Conformation
D003839:Deoxyadenosines; D005456:Fluorescent Dyes; C058118:2'-deoxyadenosine