title: Evolution from macular pseudohole to lamellar macular hole - spectral domain OCT study.
abstract: BACKGROUND
  The pathogenesis of macular pseudohole (MPH) is supposed to be different from that of macular lamellar hole (LMH). MPH is thought to be caused by centripetal contraction of previously present epiretinal membrane. LMH is considered to be an effect of abortive process of full-thickness macular hole formation, or a result of de-roofing of a foveal cyst in persistent cystoid macular oedema. In most cases of LMH, epiretinal membranes are present. The aim of this paper is to show that LMH and MPH may have a common origin and that LMH may evolve from MPH as an epiretinal membrane contracts.
  
  
  METHODS
  Observational two-case series of patients with MPH and epiretinal membrane. Spectral domain optical coherence tomography (SD-OCT) was performed during follow-up.
  
  
  RESULTS
  In 6 months of follow-up in case 1 and 2 months in case 2, MPH progressed to non-full-thickness macular defect, fulfilling the criterion of LMH in SD-OCT. Non-vitreous interface traction was detected.
  
  
  CONCLUSIONS
  SD-OCT proves that MPH may progress to LMH without any vitreous traction. Progressive contraction of epiretinal membranes may be a cause of both MPH and LMH, being an advanced stage of the same non-full-thickness macular disorder.
authors: Klinika Okulistyczna Jasne Blonia, ul. Rojna 90, 91-134, Lodz, Poland. shadowell@wp.pl
authors: Janusz
authors: J
authors: Michalewski
authors: Zofia
authors: Z
authors: Michalewska
authors: Krzysztof
authors: K
authors: Dzięgielewski
authors: Jerzy
authors: J
authors: Nawrocki
mesh_terms: D000328:Adult; D000368:Aged; D018450:Disease Progression; D019773:Epiretinal Membrane / Q000150:complications* / Q000175:diagnosis; D005128:Eye Diseases / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000473:pathology