title: Laparoscopy for stage IV melanoma in two organs.
abstract: Metastatic melanoma remains a disease associated with poor outcomes. Traditionally, surgical intervention plays a minimal role in its treatment. However, more recent studies document that complete surgical resection of distant metastases is associated with 5-year survival rates of 15% to 30%. These rates are greater than that reported for single-agent or combination chemotherapy, biologic agents or immunotherapy. This case report outlines a unique presentation of stage IV melanoma within the gastrointestinal tract located in 2 different organs. On the basis of the patient's clinical findings, laparoscopic surgery was performed for palliation of intestinal obstruction and bleeding. This approach resulted in less postoperative pain, earlier mobilization, and a faster return to daily activities. To our knowledge, this case details the only known account that uses a laparoscopic approach to palliate stage IV melanoma at 2 synchronous sites; the stomach and small bowel. The literature regarding the treatment of metastatic melanoma is also briefly reviewed.
authors: Department of Surgery, The George Washington University Hospital, Washington, DC 20037, USA.
authors: Jason
authors: J
authors: Kasza
authors: Francisco
authors: F
authors: Espinel
authors: Fatima
authors: F
authors: Khambaty
authors: Showkat
authors: S
authors: Bashir
authors: Fred
authors: F
authors: Brody
mesh_terms: D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007414:Intestinal Neoplasms / Q000556:secondary / Q000601:surgery*; D010535:Laparoscopy; D008545:Melanoma / Q000556:secondary* / Q000601:surgery*; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*