title: C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO.
abstract: We have started a space experiment using an experimental organism, the nematode Caenorhabditis elegans, in the Japanese Experiment Module, KIBO, of the International Space Station (ISS). The specimens were boarded by space shuttle Atlantis on mission STS-129 which launched from NASA Kennedy Space Center on November 16, 2009. The purpose of the experiment was several-fold: (i) to verify the efficacy of RNA interference (RNAi) in space, (ii) to monitor transcriptional and post-translational alterations in the entire genome in space, and (iii) to investigate mechanisms regulating and countermeasures for muscle alterations in response to the space environment. In particular, this will be the first study to utilize RNAi in space.
authors: Graduate School of Life Sciences, Tohoku University, Sendai, 980-8577, Japan.
authors: Atsushi
authors: A
authors: Higashitani
authors: Toko
authors: T
authors: Hashizume
authors: Tomoko
authors: T
authors: Sugimoto
authors: Chihiro
authors: C
authors: Mori
authors: Kanako
authors: K
authors: Nemoto
authors: Timothy
authors: T
authors: Etheridge
authors: Nahoko
authors: N
authors: Higashitani
authors: Takako
authors: T
authors: Takanami
authors: Hiromi
authors: H
authors: Suzuki
authors: Keiji
authors: K
authors: Fukui
authors: Takashi
authors: T
authors: Yamazaki
authors: Noriaki
authors: N
authors: Ishioka
authors: Nathaniel
authors: N
authors: Szewczyk
authors: Akira
authors: A
authors: Higashibata