Three cases of acute fatty liver of pregnancy: postpartum clinical course depends on interval between onset of symptoms and termination of pregnancy.
We report our experience with three cases of acute fatty liver of pregnancy. Case 1 complained of hydrodipsia 4 days before delivery. Case 2 presented with nausea, vomiting and dizziness 6 days before delivery. Case 3 developed loss of appetite and general fatigue with jaundice 10 days before delivery. They underwent termination of pregnancy after diagnosis was made. Case 3 still developed hepatic encephalopathy, and finally she required liver transplantation. We hypothesise that the interval between the onset of symptoms and termination of pregnancy is an important factor for acuity of the disorder and patient morbidity or mortality.
Aso
Kaai
K
Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hojo
Satoshi
S
Yumoto
Yasuo
Y
Fukushima
Kotaro
K
Miyazaki
Masayuki
M
Kotoh
Kazuhiro
K
Wake
Norio
N
D000208:Acute Disease; D000328:Adult; D036861:Delivery, Obstetric / Q000534:rehabilitation*; D005234:Fatty Liver / Q000175:diagnosis* / Q000534:rehabilitation / Q000628:therapy*; D005260:Female; D005865:Gestational Age; D006801:Humans; D049590:Postpartum Period / Q000502:physiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000534:rehabilitation / Q000628:therapy*; D011256:Pregnancy Outcome; D013997:Time Factors; D055815:Young Adult