Neuronal morphogenesis: worms get an EFF in dendritic arborization.
The development of neuronal dendritic trees involves positive and negative control of growth and branching, as well as modulation of the spacing and orientation of branches. A new study reveals the importance of a membrane fusogen in the dendrite arborization of a pair of highly-branched worm sensory neurons.
Shrestha
Brikha R
BR
Department of Physiology and Cellular Biophysics, Columbia University, 630 W. 168th St. P&S 12-403, New York, NY 10032, USA.
Grueber
Wesley B
WB
D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology / Q000378:metabolism / Q000648:ultrastructure; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism / Q000502:physiology*; D003712:Dendrites / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure; D008562:Membrane Glycoproteins / Q000378:metabolism / Q000502:physiology*; D009024:Morphogenesis / Q000502:physiology; D009619:Nociceptors / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure
D029742:Caenorhabditis elegans Proteins; C470734:EFF-1 protein, C elegans; D008562:Membrane Glycoproteins