Malignant pleural mesothelioma with associated minimal change disease and acute renal failure.
Paraneoplastic manifestations in malignant pleural mesothelioma are rare. We report a case of malignant pleural mesothelioma associated with minimal change disease (MCD). A 58-year-old man with occupational exposure to asbestos presented with severe peripheral edema, heavy proteinuria, and acute renal failure shortly after the diagnosis of mesothelioma had been confirmed. The renal biopsy demonstrated MCD. The underlying pathogenesis of this association remains unknown.
Li
Jordan Y Z
JY
Department of Renal Medicine, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia. jordan.li@health.sa.gov.au
Yong
Tuck Y
TY
Kuss
Bryone J
BJ
Klebe
Sonja
S
Kotasek
Dusan
D
Barbara
Jeffrey A J
JA
D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000209:etiology / Q000473:pathology / Q000628:therapy; D010997:Pleural Neoplasms / Q000150:complications* / Q000473:pathology* / Q000628:therapy