title: [Structure of the sweat glands in essential axillar hyperhidrosis and after its surgical treatment].
abstract: The structure of sweat glands in their skin portions in axillar regions was investigated in essential hyperhydrosis and after its treatment using mechanical curettage, performed solely or in combination with ultrasonic destruction. There was shown, that hyperhydrosis is accompanied by the sweat glands canaliculus secretory portion enlargement and their diameter as well. Additionally, the secretory epithelium area is practically enhanced twice as in a control and its thickness - in 1.5 times. Curettage is accompanied with removal, along with hypoderma, of majority of the sweat glands terminal portions and, due to evolvement of a dense connective tissue regenerate, prophylaxes their regeneration with a staged hypotrophy of residual secretory portions. The combined application of curettage with ultrasonic destruction, during treatment of hyperhydrosis, secures more prominent, alike while only curettage performance, reduction of terminal parts of sweat glands. It takes place on background of the inflammatory reaction reduction and the connective tissue subtle regenerate formation. Surgical methods of treatment, alike botulotoxin injections, secures more pronounced and persistent reduction of sweat glands in hyperhydrosis.
authors: P A
authors: PA
authors: Denyshchuk
authors: O M
authors: OM
authors: Hrabovyĭ
mesh_terms: D001365:Axilla; D003475:Curettage / Q000379:methods*; D006801:Humans; D006945:Hyperhidrosis / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D013545:Sweat Glands / Q000378:metabolism / Q000601:surgery* / Q000648:ultrastructure*; D016896:Treatment Outcome; D014464:Ultrasonic Therapy / Q000379:methods*