Pulse-oximetric measurement of prilocaine-induced methemoglobinemia in regional anesthesia.
BACKGROUND
The Masimo Radical 7(®) is a new pulse CO oximeter designed to measure methemoglobin. The device has not been evaluated in a clinical setting.


METHODS
In this prospective observational study we compared the arterial methemoglobin levels and the corresponding pulse CO-oximetric values of the Radical 7(®) in regional anesthesia with prilocaine.


RESULTS
We analyzed 360 data pairs with methemoglobin values up to 6.6%. The mean bias and limits (± 1.96 sd) of the device were 0.27% (± 1.33%).


CONCLUSIONS
We found a high degree of agreement in measurement of methemoglobin between the 2 methods.
Soeding
Peter
P
Department of Anesthesiology, University Clinic of Schleswig-Holstein, Luebeck, Germany. peter.soeding@web.de
Deppe
Matthias
M
Gehring
Hartmut
H
D000765:Anesthesia, Conduction / Q000009:adverse effects*; D006801:Humans; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis* / Q000378:metabolism; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods* / Q000592:standards; D011318:Prilocaine / Q000009:adverse effects*; D011446:Prospective Studies
D011318:Prilocaine