title: Assessment of in vivo calculation with ultrasonography compared to physical sections in vitro: a stereological study of prostate volumes.
abstract: We compared three methods for the determination of prostate volume: prostate volume measured via transrectal ultrasonography (TRUS); the Cavalieri method for measuring physical sections; and volume by displacement. TRUS volumes were calculated by the prolate ellipsoid volume formula. Five patients underwent TRUS examination of the prostate prior to radical prostatectomy; specimens were measured when freshly excised. Mean prostate volume by fluid displacement, before formalin fixation was 52.8 ± 21.5 cm(3), and after formalin fixation 50.4 ± 20.9 cm(3). Volumes determined by the Cavalieri principle (point-counting and planimetry) were 47.8 ± 19.3 and 49.1 ± 20.5 cm(3); volume measured by TRUS was 42.9 ± 21.9 cm(3). Thus TRUS underestimated prostate volume by 21.4%, but excellent agreement was found between actual volume and point counting techniques. We believe that the classic ellipsoid formula is inadequate for determining prostate volume.
authors: Department of Anatomy, Erciyes University School of Medicine, 38000, Kayseri, Turkey. acerniyazi@yahoo.com
authors: Niyazi
authors: N
authors: Acer
authors: Mustafa
authors: M
authors: Sofikerim
authors: Tolga
authors: T
authors: Ertekin
authors: Erdoğan
authors: E
authors: Unur
authors: Mahmut
authors: M
authors: Çay
authors: Figen
authors: F
authors: Öztürk
mesh_terms: D000368:Aged; D000465:Algorithms; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011467:Prostate / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D014463:Ultrasonography