Heterocyclic compounds and aromatic diglycosides from Bretschneidera sinensis.
Two new heterocyclic compounds, bretschneiderazines A and B (1, 2), three new aromatic diglycosides, bretschneiderosides A-C (3-5), and three known aromatic diglycosides, 6-8, were isolated from Bretschneidera sinensis. The structure of bretschneiderazine A (1) was confirmed by single-crystal X-ray diffraction analysis. Bretschneiderazine A (1) showed moderate activity against the NCI-H446 cell line.
Liu
Chun-Mei
CM
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China.
Li
Bo
B
Shen
Yun-Heng
YH
Zhang
Wei-Dong
WD
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045325:HCT116 Cells; D018922:HL-60 Cells; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D006574:Heterocyclic Compounds, 2-Ring; C552989:bretschneiderazine A; C552990:bretschneiderazine B; C552986:bretschneideroside A; C552987:bretschneideroside B; C552988:bretschneideroside C