title: Carcinoid tumor metastatic to the tarsal conjunctivae.
abstract: A 64-year-old woman who had been diagnosed with carcinoid tumor of the large intestine over a decade earlier presented with an acute right periorbital inflammatory reaction. On examination, 2 disc-shaped, gelatinous masses were noted on the right upper and lower tarsal conjunctivae. Excisional biopsies of these masses revealed metastatic carcinoid tumor. Her total burden of metastatic carcinoid tumor continued to increase during 2 years of follow-up, with new metastatic foci in the right choroid, in the left upper and lower eyelids, and subcutaneously in the neck and chest. Despite a comprehensive treatment approach including radionuclide therapy with the somatostatin peptide analog, Y-DOTATOC, the patient succumbed to the disease and died. The authors report an unusual case of a gastrointestinal carcinoid tumor metastatic to the tarsal conjunctivae, eyelids, choroid, and orbit.
authors: Departments of Ophthalmology, New Jersey Medical School, Newark, New Jersey 07103, USA.
authors: Hyunjin Jane
authors: HJ
authors: Kim
authors: Roman
authors: R
authors: Shinder
authors: Neena
authors: N
authors: Mirani
authors: Paul D
authors: PD
authors: Langer
mesh_terms: D002276:Carcinoid Tumor / Q000532:radiotherapy / Q000556:secondary*; D002430:Cecal Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D003230:Conjunctival Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D005143:Eyelids / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015282:Octreotide / Q000031:analogs & derivatives / Q000627:therapeutic use; D014792:Visual Acuity; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
chemical_list: D015021:Yttrium Radioisotopes; D015282:Octreotide; C106246:Edotreotide