Copper-catalyzed multicomponent reaction: synthesis of 4-arylsulfonylimino-4,5-dihydrofuran derivatives.
A series of 4-arylsulfonylimino-4,5-dihydrofurans (14 examples) were efficiently synthesized in good to excellent yields by using the copper-catalyzed three-component reaction between sulfonyl azides, phenylacetylene, and beta-ketoesters in tetrahydrofuran (THF) at 40 degrees C for 8 h in the presence of triethylamine (TEA). A plausible mechanism for this process is proposed.
Shang
Yongjia
Y
Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Key Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, People's Republic of China. shyj@mail.ahnu.edu.cn
Ju
Kai
K
He
Xinwei
X
Hu
Jinsong
J
Yu
Shuyan
S
Zhang
Min
M
Liao
Kaisheng
K
Wang
Lifen
L
Zhang
Ping
P
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D005663:Furans; D007454:Iodides; D003300:Copper; C073870:cuprous iodide