title: Direct renin inhibitors as a new therapy for hypertension.
authors: Novartis Pharmaceuticals Corp, Institutes for BioMedical Research, East Hanover, New Jersey, USA.
authors: Randy L
authors: RL
authors: Webb
authors: Nikolaus
authors: N
authors: Schiering
authors: Richard
authors: R
authors: Sedrani
authors: Jürgen
authors: J
authors: Maibaum
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000737:chemistry* / Q000494:pharmacology; D001665:Binding Sites; D018360:Crystallography, X-Ray; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008958:Models, Molecular; D015394:Molecular Structure; D057786:Peptidomimetics / Q000737:chemistry* / Q000494:pharmacology; D010880:Piperidines / Q000737:chemistry / Q000494:pharmacology; D011956:Receptors, Cell Surface / Q000819:agonists / Q000378:metabolism; D012083:Renin / Q000378:metabolism; D013329:Structure-Activity Relationship; D000093342:Prorenin Receptor; D000092502:Renin Inhibitors
chemical_list: D000959:Antihypertensive Agents; D057786:Peptidomimetics; D010880:Piperidines; D011956:Receptors, Cell Surface; D012083:Renin; D000093342:Prorenin Receptor; D000092502:Renin Inhibitors