title: Are adolescents' decisions about prenatal screening for Down syndrome informed? A controlled, prospective study.
abstract: OBJECTIVE
  Maternal serum screening is routinely offered to pregnant women in public hospitals in Victoria, Australia, regardless of their age. The aim of this study was to determine whether pregnant adolescents are less likely to make informed choices about undertaking this test than adult pregnant women.
  
  
  METHODS
  Controlled, prospective design.
  
  
  METHODS
  Public hospital antenatal clinics in Victoria, Australia.
  
  
  METHODS
  Adolescents up to 20 years of age were recruited at young mothers' clinics before they were offered second trimester maternal screening. They completed self-report questionnaires prior to maternal serum screening and again after the screening result was known.
  
  
  METHODS
  A validated measure of informed choice was used to determine whether adolescents made informed choices about undertaking second trimester maternal serum screening.
  
  
  RESULTS
  Complete data were available for 147 adolescents. These data were combined with data from 85 adults which had been collected in an identical way. Ten percent of the adolescents made informed decisions about having the maternal serum screening, compared with 37% of the adult participant group (P < 0.05). Adolescent women were significantly less likely to make an informed choice than adult women, when relevant demographic and reproductive history variables were controlled for (adjusted OR = 0.25; P = 0.004; 95% CI for OR: 0.10, 0.63).
  
  
  CONCLUSIONS
  Few pregnant adolescents made informed decisions about maternal serum screening. Clinicians face a challenge to improve adolescents' knowledge about maternal serum screening.
authors: Centre for Women's Health, Gender and Society, School of Population Health, University of Melbourne, Melbourne, Victoria, Australia. kwynter@unimelb.edu.au
authors: Karen H
authors: KH
authors: Wynter
authors: Heather J
authors: HJ
authors: Rowe
authors: Jane R
authors: JR
authors: Fisher
authors: Mardiana
authors: M
authors: Lee
authors: Julie A
authors: JA
authors: Quinlivan
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D003657:Decision Making; D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D010353:Patient Education as Topic; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000523:psychology*; D011795:Surveys and Questionnaires
chemical_list: D015415:Biomarkers