Cerebral developmental venous anomalies.
BACKGROUND
Cerebral developmental venous anomalies (DVAs) are the most frequently encountered cerebral vascular malformation. As such, they are often observed incidentally during routine CT and MRI studies. Yet, what DVAs represent from a clinical perspective is frequently not common knowledge and DVAs, therefore, still generate uncertainty and concern amongst physicians. This article reviews our current understanding of developmental venous anomalies.


RESULTS
In the majority of cases, DVAs follow a benign clinical course. On rare occasions, DVAs become symptomatic generally due to an underlying associated vascular malformation such as cavernous malformations or thrombosis of the collecting vein. Rare forms of DVAs include arterialized DVAs and DVAs involved in the drainage of sinus pericranii, which warrant additional investigation by digital subtraction angiography. Cerebral abnormalities such as atrophy, white matter lesions and calcifications within the drainage territory of asymptomatic DVAs, are often identified on CT or MR imaging studies and likely represent secondary changes due to venous hypertension. There is increasing evidence that DVAs have a propensity for developing venous hypertension, which is thought to be the cause of associated cavernous malformations and parenchymal abnormalities.


CONCLUSIONS
DVAs represent variations of the normal cerebral venous angioarchitecture and by enlargement follow an uneventful clinical course. Complications can, however, occur and their management requires a thorough understanding of the nature of DVAs, including their frequent coexistence with other types of vascular malformation, and the existence of more complex but rare forms of presentation, such as the arterialized DVAs.
San Millán Ruíz
Diego
D
Neuroradiology Unit, Department of Diagnostic and Interventional Radiology, Hospital of Sion, Avenue du Grand-Champsec 80, 1951, Sion, Valais, Switzerland. diego.san-millan-ruiz@rsv-gnw.ch
Gailloud
Philippe
P
D001164:Arteriovenous Fistula / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D001284:Atrophy; D020787:Central Nervous System Venous Angioma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D002533:Cerebral Angiography; D002550:Cerebral Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D002648:Child; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed