Influence of repetitive transcranial magnetic stimulation on special symptoms in depressed patients.
Since various studies, including multi-centre studies, investigating the effect of repetitive transcranial magnetic stimulation (rTMS) in depression have shown different results, it is now important to research, which symptoms of depression are most responsive to this kind of non-invasive brain stimulation. Furthermore, an increasing interest of rTMS as a potential tool for treatment of neurological and psychiatric disorders should be recorded. Therefore, it is critical to investigate dopaminergic functional interactions in the prefrontal cortex, and in particular, the effect of dorsolateral prefrontal cortex stimulation on clinical symptoms depending on dopaminergic concentrations in various brain regions. This short review summarizes important preliminary data, which focus on the symptom-oriented effects of rTMS in depression.
Höppner
Jacqueline
J
Department of Psychiatry and Psychotherapy, Centre of Nervous Disease, University of Rostock, Rostock, Germany. jacqueline.hoeppner@med.unirostock.de
Berger
Christoph
C
Walter
Uwe
U
Padberg
Frank
F
Buchmann
Johannes
J
Herwig
Uwe
U
Domes
Gregor
G
D003866:Depressive Disorder / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D004298:Dopamine / Q000502:physiology; D006801:Humans; D009068:Movement / Q000502:physiology; D015337:Multicenter Studies as Topic; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology / Q000628:therapy; D011597:Psychomotor Performance / Q000502:physiology; D009435:Synaptic Transmission / Q000528:radiation effects; D050781:Transcranial Magnetic Stimulation
D004298:Dopamine