Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2'-deoxyinosine.
A novel electrochemical biosensor for the genotyping/detection of single-nucleotide polymorphisms (SNPs) of trace oral-cancer salivary DNA based on junction probes containing 2'-deoxyinosine (dI) residues is described.
Zhang
Jing
J
Key Lab of Analysis and Detection for Food Safety of Ministry of Education, Department of Chemistry, Fuzhou University, Fujian 350108, China.
Wu
Xiaoyan
X
Chen
Pingping
P
Lin
Ningting
N
Chen
Jinghua
J
Chen
Guonan
G
Fu
Fengfu
F
D015374:Biosensing Techniques; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004563:Electrochemistry; D005838:Genotype; D007288:Inosine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000235:genetics; D015345:Oligonucleotide Probes / Q000737:chemistry / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
D015345:Oligonucleotide Probes; D007288:Inosine; D004247:DNA; C012271:deoxyinosine