Faecal carriage of extended-spectrum β-lactamase-producing and AmpC β-lactamase-producing bacteria among Danish army recruits.
During May and June 2008, 84 Danish army recruits were tested for faecal carriage of extended-spectrum β-lactamase (ESBL)-producing and AmpC β-lactamase-producing bacteria. Three ESBL-producing (CTX-M-14a) Escherichia coli isolates, two AmpC-producing (CMY-2) E. coli isolates and one AmpC-producing (CMY-34) Citrobacter freundii isolate were detected. Two of the CTX-M-14a E. coli isolates had similar pulsed-field gel electrophoresis and multilocus sequence typing profiles, indicating the same origin or transmission between the two army recruits. The bla(CTX-M-14a) genes were transferable to an E. coli recipient. These commensal bacteria therefore constitute a reservoir of resistance genes that can be transferred to other pathogenic bacteria in the intestine.
Hammerum
A M
AM
Statens Serum Institut, Copenhagen, Denmark.
Lester
C H
CH
Jakobsen
L
L
Porsbo
L J
LJ
D000293:Adolescent; D000328:Adult; D015373:Bacterial Typing Techniques; D002353:Carrier State / Q000382:microbiology*; D016971:Citrobacter freundii / Q000201:enzymology* / Q000302:isolation & purification; D003718:Denmark; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000201:enzymology* / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008889:Military Personnel; D058885:Multilocus Sequence Typing; D055815:Young Adult; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases