title: Dentifrices--an update.
abstract: OBJECTIVE
  The objective of this paper was to review the published evidence concerning the efficacy and potential for adverse reactions of modern dentifrices toothpastes.
  
  
  METHODS
  Publications cited on MEDLINE since 1990. Some further pre-1990 publications are also referenced.
  
  
  METHODS
  Studies concerning the efficacy of dentifrices and their components and any related putative adverse incidents.
  
  
  METHODS
  Papers were scrutinised for scientific and trial data.
  
  
  RESULTS
  Data concerning the efficacy of dentifrice components were summarised.
  
  
  CONCLUSIONS
  The efficacy of fluoride salts in dentifrices in reducing dental caries is well established. Toothpastes, containing triclosan, are effective in improving plaque control, gingivitis and periodontal health. Other toothpaste formulations are effective in reducing the formation of calculus, extrinsic tooth stain, dentine sensitivity and oral malodour. The consumer now has available a range of toothpastes which deliver oral health benefits. Adverse reactions to toothpastes are rare but should be considered in unexplained skin or respiratory allergies and gingival or lip lesions.
authors: National Fluoride Information Centre, Coupland 111 Building, University of Manchester, Oxford Road, Manchester M13 9PL.
authors: Robin
authors: R
authors: Davies
authors: Crispian
authors: C
authors: Scully
authors: Antony J
authors: AJ
authors: Preston
mesh_terms: D003802:Dentifrices / Q000737:chemistry
chemical_list: D003802:Dentifrices