title: Epidemiological characteristics of brucellosis in Serbia, 1980-2008.
abstract: OBJECTIVE
  To analyze the epidemiological characteristics of human brucellosis in Serbia from 1980 to 2008 and the most important factors affecting its emergence and spread.
  
  
  METHODS
  Public sources of data on brucellosis were used, including official reports of infectious diseases and epidemics, as well as monthly and annual reports of the Serbia and Vojvodina Institutes of Public Health.
  
  
  RESULTS
  From 1980 through 2008, there were 1521 human brucellosis cases in Serbia. The annual number ranged from 2 in 2000 to 324 in 1991. Infections occurred more often in men (67% of cases) than in women (odds ratio, 2.17; 95% confidence interval, 1.57-3.00; chi2=24.52, P<0.001). The largest number of patients over the entire study period (1184) was recorded in Kosovo and Metohija, which accounted for 78% of the total number of patients. The maximum incidence rate in Kosovo and Metohija was 12 per 100,000 in 1991. In Vojvodina, the first autochthonous human cases of brucellosis were recorded in 1999, and 101 affected persons were registered by the end of 2008. During the period 1994-2008, the largest number of patients in Serbia was recorded from June to September (310 of 623 cases, 50%). The disease was most prevalent among people aged 30-49 years, accounting for 81 of 177 (46%) of the cases in Serbia from 1999 to 2008.
  
  
  CONCLUSIONS
  Brucellosis has been a significant public health concern in Serbia. This problem may be solved by joint efforts of all relevant factors, first of all human and veterinary medical services.
authors: Department of Epidemiology, Military Medical Academy, 11000 Belgrade, Serbia. cekanac@ptt.rs
authors: Radovan
authors: R
authors: Cekanac
authors: Jovan
authors: J
authors: Mladenović
authors: Elizabeta
authors: E
authors: Ristanović
authors: Srdan
authors: S
authors: Lazić
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002006:Brucellosis / Q000097:blood / Q000453:epidemiology* / Q000635:transmission; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D004196:Disease Outbreaks; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D011634:Public Health; D012307:Risk Factors; D012621:Seasons; D055771:Serbia / Q000453:epidemiology; D012737:Sex Factors; D055815:Young Adult; D015047:Zoonoses / Q000453:epidemiology