title: Small bowel obstruction associated with use of a gelatin-thrombin matrix sealant (FloSeal) after laparoscopic gynecologic surgery.
abstract: We report 2 cases of laparoscopic gynecologic procedures, complicated by small bowel obstruction possibly related to use of a hemostatic agent. The cause was most likely from excess material not incorporated in the hemostatic clot at the site of application. Gentle irrigation and removal of excess material from the site of application is recommended by the manufacturer of FloSeal and may reduce the risk of postoperative adhesion formation and small bowel obstruction.
authors: Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. yokos@earthlink.com
authors: Yoko
authors: Y
authors: Suzuki
authors: Thomas T
authors: TT
authors: Vellinga
authors: Olav
authors: O
authors: Istre
authors: Jon I
authors: JI
authors: Einarsson
mesh_terms: D000328:Adult; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000009:adverse effects*; D006490:Hemostatics / Q000009:adverse effects*; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D007077:Ileal Diseases / Q000209:etiology* / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology* / Q000601:surgery; D007421:Intestine, Small; D010535:Laparoscopy / Q000009:adverse effects*; D008875:Middle Aged; D000267:Tissue Adhesions / Q000209:etiology / Q000601:surgery
chemical_list: C411004:FloSeal Matrix; D006490:Hemostatics