Radical trachelectomy for clear cell carcinoma of the cervix in a 6-year old: a case report, review, and description of the surgical technique.
Clear cell carcinoma is a rare pediatric cervical cancer, seen primarily in the setting of in utero diethylstilbesterol exposure. Historically, this type of cancer has been treated with radical hysterectomy and lymph-node dissection, rendering patients incapable of carrying a pregnancy in the future. We describe a young patient with clear cell carcinoma of the cervix who, through a multidisciplinary collaboration, was managed by a fertility-sparing alternative surgical approach--a radical trachelectomy. We present the surgical technique and review the current evidence regarding the use of radical trachelectomy as a fertility-sparing procedure in young patients with cervical cancer.
Lester
Felicia C
FC
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA 02120, USA. flester@partners.org
Farmer
Diana L
DL
Rabban
Joseph T
JT
Chen
Lee-May
LM
D018262:Adenocarcinoma, Clear Cell / Q000473:pathology / Q000601:surgery*; D000328:Adult; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D002648:Child; D005260:Female; D005298:Fertility / Q000502:physiology*; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008197:Lymph Node Excision; D011247:Pregnancy; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*