title: Recurrent intraoral HSV-1 infection: A retrospective study of 58 immunocompetent patients from Eastern Europe.
abstract: OBJECTIVE
  To revise the clinical features of the recurrent intraoral herpetic infection (RIOH) with respect to precipitating factors, demographic, clinical features and outcome.
  
  
  METHODS
  Fifty-eight, unrelated Caucasian, immunocompetent patients with positive laboratory test for intraoral Herpes simplex virus infection were studied.
  
  
  RESULTS
  The mean age in the women's group (n=42) was 41.23 years (± 21.73) and in the men's group was 32.25 years (±15.68). Possible trigger factors were identified in 9 cases (15.5%). General symptoms were noted in 20 cases (34.48%). Most of patients in this study presented multiple lesions. 14 patients had vermillion lesions associated with intraoral lesions. In most of the cases both fixed and mobile mucosa was concomitantly involved. Treatment was prescribed in order to control the symptoms and to shorten the evolution with minimal side effects.
  
  
  CONCLUSIONS
  Intraoral secondary herpetic infection could be polymorphous and sometimes associated with general symptoms. The recognition of its atypical features may prevent unnecessary and costly investigations and treatments for unrelated though clinically similar-appearing disorders.
authors: Department of Oral Medicine Oral Pathology, Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors: Serban
authors: S
authors: Tovaru
authors: Ioanina
authors: I
authors: Parlatescu
authors: Mihaela
authors: M
authors: Tovaru
authors: Lucia
authors: L
authors: Cionca
authors: Paolo-Giacomo
authors: PG
authors: Arduino
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis*; D018259:Herpesvirus 1, Human; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012383:Romania; D055815:Young Adult