title: [Treatment goals in pulmonary arterial hypertension].
abstract: A goal-oriented treatment strategy is recommended in patients with pulmonary arterial hypertension (PAH). The current treatment goals are based on regular assessment of clinical parameters that have been demonstrated as prognostic factors at the time of initial evaluation. The prognostic value of the course of these parameters assessed at follow-up on PAH-specific therapies is unknown. The aim of the EFORT clinical study is to analyse the prognostic factors assessed at follow-up in patients with PAH, to provide more accurate information in terms of treatment goals than the simple analysis of prognostic factors at baseline. This clinical research project should help to establish new recommendations for the management of patients with PAH. The impact of these new therapeutic approaches on long-term survival of patients with PAH is a major challenge in the near future.
authors: Université Paris-Sud XI, Faculté de Médecine, Le Kremlin-Bicêtre, France. olivier.sitbon@abc.aphp.fr
authors: Laurent
authors: L
authors: Savale
authors: Olivier
authors: O
authors: Sitbon
mesh_terms: D000465:Algorithms; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003663:Decision Trees; D016903:Drug Monitoring; D005602:France / Q000453:epidemiology; D006040:Goals; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D015337:Multicenter Studies as Topic; D009937:Organizational Objectives; D010347:Patient Care Planning / Q000458:organization & administration*; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents