Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids.
A simple and straightforward synthetic approach to potential anti-infective thiolactone-isatin hybrids led to the discovery of novel tetracyclic compounds which bear a macrocylic motif containing an unusual bridged amide bond.
Hans
Renate Hazel
RH
Department of Chemistry and Biochemistry, University of Namibia, Windhoek, Namibia. rhans@unam.na
Su
Hong
H
Chibale
Kelly
K