title: Cancer biomarkers - current perspectives.
abstract: In the recent years, knowledge about cancer biomarkers has increased tremendously providing great opportunities for improving the management of cancer patients by enhancing the efficiency of detection and efficacy of treatment. Recent technological advancement has enabled the examination of many potential biomarkers and renewed interest in developing new biomarkers. Biomarkers of cancer could include a broad range of biochemical entities, such as nucleic acids, proteins, sugars, lipids, and small metabolites, cytogenetic and cytokinetic parameters as well as whole tumour cells found in the body fluid. A comprehensive understanding of the relevance of each biomarker will be very important not only for diagnosing the disease reliably, but also help in the choice of multiple therapeutic alternatives currently available that is likely to benefit the patients. This review provides a brief account on various biomarkers for diagnosis, prognosis and therapeutic purposes, which include markers already in clinical practice as well as various upcoming biomarkers.
authors: Division of Radiation Biosciences, Institute of Nuclear Medicine & Allied Sciences, Delhi, India.
authors: Anant Narayan
authors: AN
authors: Bhatt
authors: Rohit
authors: R
authors: Mathur
authors: Abdullah
authors: A
authors: Farooque
authors: Amit
authors: A
authors: Verma
authors: B S
authors: BS
authors: Dwarakanath
mesh_terms: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor / Q000235:genetics* / Q000378:metabolism*; D004279:DNA, Viral; D044127:Epigenesis, Genetic / Q000235:genetics*; D006514:Hepatitis B Surface Antigens; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D009360:Neoplastic Cells, Circulating; D014411:Neoplastic Stem Cells / Q000166:cytology; D050378:T-Lymphocytes, Regulatory / Q000166:cytology
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens