title: Relations between mucosal immunity and children's mental health: the role of child sex.
abstract: This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age=9.85years; SD=.98years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.
authors: Department of Psychology, University of Kentucky, Lexington, KY 40506, USA. peggy.keller@uky.edu
authors: Peggy S
authors: PS
authors: Keller
authors: Mona
authors: M
authors: El-Sheikh
authors: Brian
authors: B
authors: Vaughn
authors: Douglas A
authors: DA
authors: Granger
mesh_terms: D001007:Anxiety / Q000276:immunology / Q000523:psychology; D002648:Child; D003863:Depression / Q000276:immunology / Q000523:psychology; D005260:Female; D006801:Humans; D018928:Immunity, Mucosal; D007071:Immunoglobulin A, Secretory / Q000032:analysis / Q000276:immunology*; D015850:Interleukin-6 / Q000032:analysis / Q000276:immunology*; D008297:Male; D008603:Mental Health; D012463:Saliva / Q000737:chemistry / Q000276:immunology*; D012737:Sex Factors; D011795:Surveys and Questionnaires
chemical_list: D007071:Immunoglobulin A, Secretory; D015850:Interleukin-6