title: Vacuum-assisted closure with a portable system for treatment of poststernotomy mediastinitis.
abstract: The patient was a 50-year-old man with diabetes who was on insulin. Complications of mediastinitis developed after coronary bypass surgery, which had been performed for unstable angina. Upon hospital admission, the patient was treated with antibiotics, and the wound was cleaned on a daily basis. However, because the patient's fever persisted, the wound was completely opened surgically and found to be deep and large. Because the patient's condition was relatively stable, minimally invasive vacuum-assisted closure was selected. We fabricated a portable vacuum-assisted closure system that imposed few limitations on individual movement. Vacuum-assisted closure treatment resulted in both rapid abatement of fever and improved granulation. Dressings were changed once a week; the wound was closed 4 weeks after vacuum-assisted closure and healed completely. Vacuum-assisted closure may be an effective therapy for postoperative mediastinitis, and our portable vacuum-assisted closure system may significantly reduce patient distress as well as direct medical care.
authors: Department of Cardiovascular Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. shiz-d@juntendo.ac.jp
authors: Shizuyuki
authors: S
authors: Dohi
authors: Hirotaka
authors: H
authors: Inaba
authors: Keiichi
authors: K
authors: Tanbara
authors: Taira
authors: T
authors: Yamamoto
authors: Keita
authors: K
authors: Kikuchi
authors: Akie
authors: A
authors: Shimada
authors: Atsushi
authors: A
authors: Amano
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D004867:Equipment Design; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000295:instrumentation*; D013211:Staphylococcus aureus / Q000302:isolation & purification; D056346:Sternotomy / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents