Primary synovial sarcoma of the lung with intra-cardiac extension.
Synovial sarcomas are a distinct clinical entity occurring most often in the lower extremities. They account for 10-14% of all soft tissue sarcomas. Pulmonary synovial sarcomas are quite rare and account for less than 0.5% of all intra-thoracic neoplasms. We present the first reported case of primary pulmonary synovial sarcoma with intra cardiac extension in a 53-year-old male who presented with chronic cough. Imaging revealed a large right upper lobe mass extending through the superior pulmonary veins into the left atrium. The patient underwent a right total pneumonectomy with extraction of the left atrial mass and left atrial reconstruction. Pathology and immunohistochemistry was diagnostic of primary pulmonary synovial sarcoma positive for SYT-SSX1 gene fusion transcription.
Devarakonda
Veena S
VS
Division of Pulmonary, Critical Care and Sleep Medicine, Drexel University College of Medicine, Philadelphia, Pa. 19102, USA. presh76@gmail.com
Lembert
Larissa
L
Entwistle
John W
JW
Hoag
Jeffrey B
JB
D006325:Heart Atria / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011667:Pulmonary Veins / Q000473:pathology*; D013584:Sarcoma, Synovial / Q000473:pathology*