Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.
Davenport
E L
EL
Zeisig
A
A
Aronson
L I
LI
Moore
H E
HE
Hockley
S
S
Gonzalez
D
D
Smith
E M
EM
Powers
M V
MV
Sharp
S Y
SY
Workman
P
P
Morgan
G J
GJ
Davies
F E
FE
D000971:Antineoplastic Combined Chemotherapy Protocols; D017209:Apoptosis / Q000187:drug effects*; D001559:Benzhydryl Compounds / Q000494:pharmacology; D016227:Benzoquinones / Q000494:pharmacology; D015153:Blotting, Western; D002453:Cell Cycle; D049109:Cell Proliferation; D004357:Drug Synergism; D050884:HSP72 Heat-Shock Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D047029:Lactams, Macrocyclic / Q000494:pharmacology; D009101:Multiple Myeloma / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology*; D011760:Pyrrolidinones / Q000494:pharmacology; D012333:RNA, Messenger / Q000235:genetics; D034741:RNA, Small Interfering / Q000494:pharmacology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D051742:Transcription Factor CHOP / Q000235:genetics / Q000378:metabolism; D014407:Tumor Cells, Cultured
D001559:Benzhydryl Compounds; D016227:Benzoquinones; C497249:DDIT3 protein, human; D050884:HSP72 Heat-Shock Proteins; D018841:HSP90 Heat-Shock Proteins; C410027:KNK 437; D047029:Lactams, Macrocyclic; D011760:Pyrrolidinones; D012333:RNA, Messenger; D034741:RNA, Small Interfering; D051742:Transcription Factor CHOP; C112765:tanespimycin