title: [Our and foreign experience in surgical treatment of CIN III-cold knife conisation versus LLETZ].
abstract: OBJECTIVE
  Our aim was to assess the treatment results of patients with CIN III- surgically treated with cold knife cone biopsy compared with the results of treatment with LLETZ and laser conisation.
  
  
  METHODS
  600 patients were assessed and researched for 10 years period. Some of them were from the Specialized Hospital for Active Treatment in Oncology-Sofia, some from RHW and some from the Medical University of Varna-Cathedra of Obstetrics and Gynaecology. 350 patients were operated by the classical method- cold knife conisation, 200 by LLETZ and 50 by laser cone biopsy.
  
  
  RESULTS
  We didn't find any difference in patients age, their cytological results and the results of their treatment. The LLETZ showed good results according to resected margins. The same good results were observed with laser conisation. Invasive disease and recurrence were observed in 150 patients--50 of them having adenocarcinoma in situ.
  
  
  CONCLUSIONS
  Our research showed that there is no difference in the results of both groups- treated by the classical way--cold knife conisation or by LLETZ and laser conisation.
authors: M
authors: M
authors: Boyadzhieva
authors: I
authors: I
authors: Atanassova
authors: V
authors: V
authors: Dimitrova
authors: S
authors: S
authors: Zaharieva
authors: Tz
authors: T
authors: Tankova
authors: G
authors: G
authors: Grozeva
authors: K
authors: K
authors: Todorova
authors: V
authors: V
authors: Stoykova
authors: S
authors: S
authors: Kedikova
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D019092:Conization / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*