title: [Retroperitoneal laparoscopic adrenalectomy for larger adrenal tumor].
abstract: OBJECTIVE
  To evaluate the feasibility and safety of retroperitoneal laparoscopic adrenalectomy for larger adrenal tumor.
  
  
  METHODS
  A retrospective cohort study of patients who underwent retroperitoneal laparoscopic adrenalectomy in a single unit from July 2004 to December 2008 was undertaken, in which 53 cases were divided into 2 groups according to size as estimated by group A [n=13; age: 45+/-18 years; size: (7.6+/-1.2) cm, maximum diameter of tumor larger than 6 cm] and group B [n=40; age: (49+/-12) years; size: (4.0+/-0.9) cm, between 3 and 6 cm].
  
  
  RESULTS
  All procedures were performed successfully. In comparison between the 2 groups ,the mean operative time [(127+/-77) min vs (107+/-47) min, P<0.05] and estimated blood loss [(167+/- 223) mL vs (65+/-60) mL,P<0.01] had significant difference. The intraoperative complications and blood transfusion rate in group A were higher than those of group B (23% vs 12.5% and 15% vs 2.5%),no difference was noted in their hospital stay after operation [(7.1+/-1.1) d vs (5.5+/-0.7) d, P>0.05]. Group A was followed up for 25+/-14 months,during which time no local recurrence was noted in 8 cases, 3 cases were missed ,and 2 cases were alive with hydronephrosis. Group B was followed up for 29+/-14 months, during which time 30 cases were free, 9 cases were lost, and 1 case was found with real disfunction. The pathology of most tumors in group A included medullary lipoma(30.8%), pheochromocytoma(23%) and ganglioneuroma(23%), the others included adenoma(32.5%), pheochromocytoma(25%) and ganglioneuroma(17.5%) in group B.
  
  
  CONCLUSIONS
  Retroperitoneal laparoscopic adrenalectomy has best value in patients with larger adrenal tumor and it is a minimally invasive and safe procedure for skillful surgeons in the treatment of tumor size larger than 6 cm.
authors: Department of Urology, Peking University Third Hospital, Beijing 100191, China.
authors: Jian
authors: J
authors: Lu
authors: Yi
authors: Y
authors: Huang
authors: Kai
authors: K
authors: Hong
authors: Yu-qing
authors: YQ
authors: Liu
authors: Xiao-jun
authors: XJ
authors: Tian
authors: Shu-dong
authors: SD
authors: Zhang
authors: Guo-liang
authors: GL
authors: Wang
authors: Lei
authors: L
authors: Liu
authors: Lu-lin
authors: LL
authors: Ma
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005729:Ganglioneuroma / Q000601:surgery; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008067:Lipoma / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D010673:Pheochromocytoma / Q000601:surgery*; D012187:Retroperitoneal Space; D012189:Retrospective Studies; D055815:Young Adult