title: Fluoride-releasing orthodontic adhesives and topical fluoride effect on enamel caries formation: an in vitro study.
abstract: OBJECTIVE
  To examine in vitro orthodontic bonding sealants combined with daily fluoride (NaF) rinse on caries-like lesion depths.
  
  
  METHODS
  Permanent molar teeth (n = 40) were randomly divided into four treatment groups: 1: Pro-Seal, 2: Light Bond, 3: Pro-Seal with NaF rinsing, and 4: Light Bond with NaF rinsing. Orthodontic sealant material was placed on buccal surfaces of each group and surrounded by acid-resistant varnish on the buccal and a control window on the lingual. Each group underwent synthetic saliva rinsing and lesion initiation. Groups 3 and 4 were subjected to 0.05% NaF for 1 minute per day. Artificial caries were created in vitro. The specimens in each treatment group were sectioned and mean lesion depth was assessed with polarized light microscopy (water imbibition). Lesion depth was compared among the treament groups using ANOVA and Duncan's Multiple Range Test.
  
  
  RESULTS
  The ProSeal and Light Bond treatment groups exhibited significant reductions in mean lesion depths as compared to the controls (P < 0.05). ProSeal with NaF rinsing and Light Bond with NaF rinsing treatment groups exhibited significant reductions in mean lesion depth when compared to Pro Seal and Light Bond treatment without fluoride rinsing and controls (P < 0.05). The enamel-resin interfaces of all treatment groups were intact and exhibited no caries-like lesion formation.
authors: Department of Pathology, MC1-2261, Texas Children's Hospital, 6621 Fannin St., Houston, TX 77030-2313, USA.
authors: Kendra Covington
authors: KC
authors: Pratt
authors: John
authors: J
authors: Hicks
authors: Jeryl D
authors: JD
authors: English
authors: Harry I
authors: HI
authors: Bussa
authors: Catherine M
authors: CM
authors: Flaitz
authors: John M
authors: JM
authors: Powers
mesh_terms: D002327:Cariostatic Agents / Q000008:administration & dosage*; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding; D003731:Dental Caries / Q000517:prevention & control*; D006801:Humans; D008963:Molar; D009067:Mouthwashes / Q000737:chemistry; D016910:Orthodontic Brackets; D019279:Resin Cements / Q000737:chemistry*; D012969:Sodium Fluoride / Q000008:administration & dosage*
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D009067:Mouthwashes; C501632:Pro Seal; C429652:Reliance Light Bond; D019279:Resin Cements; D012969:Sodium Fluoride