Directed ortho borylation of phenol derivatives catalyzed by a silica-supported iridium complex.
The directed ortho borylation of phenol derivatives protected with an N,N-diethylcarbamoyl group was efficiently catalyzed by an immobilized monophosphine-Ir system, which was prepared in situ from [Ir(OMe)(cod)](2) and a silica-supported, compact phosphine. The utility of the carbamoyloxy group as a leaving group for metal-catalyzed cross-coupling reactions was demonstrated by its utilization in the synthesis of a terphenyl derivative.
Yamazaki
Kenji
K
Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Kawamorita
Soichiro
S
Ohmiya
Hirohisa
H
Sawamura
Masaya
M
D001896:Boron Compounds / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
D001896:Boron Compounds; D010636:Phenols; D007495:Iridium; D012822:Silicon Dioxide