title: Biliary reconstruction in pediatric live donor liver transplantation: duct-to-duct or Roux-en-Y hepaticojejunostomy.
abstract: BACKGROUND
  Duct-to-duct biliary reconstruction (DD) is currently a standard procedure in adult live donor liver transplantation (LDLT). Its pediatric feasibility, however, has rarely been reported. The goal of this study is to assess the incidence and treatment of biliary complication after pediatric LDLT with DD or Roux-en-Y hepaticojejunostomy (RY).
  
  
  METHODS
  Sixty children received LDLT between November 2005 and June 2008, and their database was reviewed.
  
  
  RESULTS
  Biliary reconstruction was achieved with DD in 14 patients and with RY in 46 patients with mean follow-up period of 26.0 and 22.3 months, respectively. The incidence of biliary leakage in the DD and RY groups was 7.1% and 8.7%, respectively, and that of stricture was 28.6% and 10.9%, respectively; but the differences were not statistically significant. Biliary stricture in the DD group tended to require revision surgery with RY and longer treatment with percutaneous transhepatic cholangiodrainage compared with that in the RY group.
  
  
  CONCLUSIONS
  Theoretical advantages of DD over RY were not confirmed in this study. Duct-to-duct biliary reconstruction tended to encounter more biliary complications, especially stricture, with more difficulty in treating it than RY. Roux-en-Y hepaticojejunostomy seems preferable to DD in the setting of pediatric LDLT, but DD must be considered when making new Roux-en-Y limb seems impossible or troublesome owing to abdominal dense adhesion or short bowel syndrome.
authors: Division of Surgery, National Center for Child Health and Development, Setagaya-Ku, Tokyo 157-8535, Japan. tanaka-h@ncchd.go.jp
authors: Hideaki
authors: H
authors: Tanaka
authors: Akinari
authors: A
authors: Fukuda
authors: Takanobu
authors: T
authors: Shigeta
authors: Tatsuo
authors: T
authors: Kuroda
authors: Takuya
authors: T
authors: Kimura
authors: Seisuke
authors: S
authors: Sakamoto
authors: Mureo
authors: M
authors: Kasahara
mesh_terms: D000713:Anastomosis, Roux-en-Y / Q000379:methods; D000714:Anastomosis, Surgical / Q000379:methods; D001652:Bile Ducts / Q000601:surgery*; D001662:Biliary Tract Surgical Procedures / Q000379:methods*; D002675:Child, Preschool; D003251:Constriction, Pathologic / Q000209:etiology; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007582:Jejunostomy / Q000379:methods*; D008099:Liver / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D019651:Plastic Surgery Procedures