[Some new tendencies in diagnosis and complex treatment of vulvar cancer--our and foreign experience].
BACKGROUND
The aim of this research work was to summarize our and foreign experience in the field of diagnosis, complex treatment and prognostic factors connected with vulvar cancer.


METHODS
We evaluated our and foreign experience for 10 years period (2000-2010) and evaluated 625 patients diagnosed and treated for vulvar cancer. We assessed the complex treatment, prognostic factors and some new tendencies towards more conservative surgical treatment of vulvar cancer.


RESULTS
The all 5 years survival rate was 70%; 10 years survival rate was 50%. The level of recurrence was 30% (187 p.), local recurrences were 50% (93 p.), the groin recurrences were 7% (13 p.). The biggest recurrence rate was in local recurrences of the vulva. Older age and metastases in lymph nodes were independent bad prognostic factors. The stages of the lymph nodes, LVSI and the stage were connected with survival and disease free survival. The different kinds of treatment were analyzed- surgery, chemo and radiotherapy. We analyzed the tendencies towards more conservative surgical treatment connected with vulvar cancer.


CONCLUSIONS
We tried to summarize our and foreign experience in the complex treatment of vulvar cancer for 10 years period. Our main idea was to show some new tendencies in the latest 10 years towards relatively more conservative treatment of this neoplasia.
Ivanov
S
S
D004358:Drug Therapy; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D011379:Prognosis; D012008:Recurrence; D015996:Survival Rate; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*