A new abietane diterpene from Glyptostrobus pensilis.
A new abietane diterpene, glypensin A (1) and four known compounds, 12-acetoxy-ent-labda-8(17), 13E-dien-15-oic acid (2), quercetin 3-O-α-L-arabinofuranoside (3), quercetin 3-O-β-D-galactopyranoside (4), β-sitosterol (5) were isolated from the branches and leaves of Glyptostrobus pensilis (Staut.) Koch. Their structures were determined by MS, 1D- and 2D-NMR means. Compound 1 showed cytotoxicity on human chronic myeloid leukemia cell line K562 (IC(50) = 21.2μM).
Zhang
Yu-Mei
YM
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 650204 Kunming, Yunnan, PR China.
Yin
Run-Ting
RT
Jia
Rui-Rui
RR
Yang
En-Hu
EH
Xu
Han-Mei
HM
Tan
Ning-Hua
NH
D045784:Abietanes / Q000737:chemistry* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D029779:Cupressaceae / Q000737:chemistry*; D006801:Humans; D020014:K562 Cells; D008958:Models, Molecular; D015394:Molecular Structure
D045784:Abietanes; D000972:Antineoplastic Agents, Phytogenic