Osseous metaplasia in a kidney allograft.
Osseous metaplasia is defined by the presence of heterotopic normal bone tissue in a soft tissue. The bone matrix is associated with osteoblasts, osteoclasts, adipocytes and haematopoietic stem cells. Osseous metaplasia pathophysiology is not well known, but many factors have been incriminated including chronic inflammation and chronic ischaemia. We describe the second case of osseous metaplasia in a kidney allograft. Numerous factors might favour its development including factors linked to transplantation failure environment.
Bataille
Stanislas
S
Université de la Méditerranée, Assistance Publique des Hôpitaux de Marseille, Centre de Néphrologie et Transplantation rénale, Hôpital Conception, 147 Boulevard Baille, Marseille Cedex 05, France. stanislas.bataille@ap-hm.fr
Daniel
Laurent
L
Legris
Tristan
T
Vacher-Coponat
Henri
H
Purgus
Raj
R
Berland
Yvon
Y
Moal
Valerie
V
D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008679:Metaplasia; D009999:Ossification, Heterotopic / Q000473:pathology*; D010011:Osteocytes / Q000473:pathology; D014184:Transplantation, Homologous