Scintigraphic findings of growth arrest lines after bisphosphonate administration in a steroid-induced osteoporosis patient: a case study.
Bisphosphonates inhibit bone resorption, and are used to treat patients who have low bone mineral density. This treatment results in the development of growth arrest lines, which typically appear parallel sclerotic lines to the growth plate on radiographs. We describe the case of a 14-year-old boy with steroid-induced osteoporosis, who was treated by pamidronate. This patient exhibited linearly increased bilateral uptake in the shafts of his femora, tibiae, radii, and ulnae that were parallel to the growth plates. A simple radiograph corresponding bone scan demonstrated linear sclerotic lines at the same sites.
Hong
Il Ki
IK
Department of Nuclear Medicine, Kyung Hee University Medical Center, Seoul, Korea.
Suh
Jin-Soon
JS
Lee
Yeon-Ah
YA
Kim
Deog-Yoon
DY
D000293:Adolescent; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004164:Diphosphonates / Q000008:administration & dosage* / Q000627:therapeutic use*; D006132:Growth Plate / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000139:chemically induced* / Q000188:drug therapy*; D011859:Radiography; D011877:Radionuclide Imaging; D013256:Steroids / Q000009:adverse effects*; D051598:Whole Body Imaging
D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D013256:Steroids