title: A new allele, HLA-B*4212, identified in a Brazilian volunteer bone marrow donors by sequence-based typing.
abstract: Here we report the discovery of a novel HLA-B allele, named B*4212 in a Brazilian volunteer bone marrow donor. The new sequence has nucleotide variation at position 496 (T→G) as compared with B*4201. This variation results in a conservative amino acid substitution from valine to glycine at codon 165 of exon 3.
authors: Laboratory of Immunogenetics and Histocompatibility, Genetics Department, Universidade Federal do Paraná, Curitiba, Brazil.
authors: S B
authors: SB
authors: Mattar
authors: C J S
authors: CJ
authors: Uehara
authors: F
authors: F
authors: Ribas
authors: R G
authors: RG
authors: Vargas
authors: P F
authors: PF
authors: Wowk
authors: F
authors: F
authors: Poerner
authors: M G
authors: MG
authors: Bicalho
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001483:Base Sequence; D001853:Bone Marrow; D001938:Brazil; D015235:HLA-B Antigens / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D017422:Sequence Analysis, DNA; D014019:Tissue Donors
chemical_list: D015235:HLA-B Antigens