title: Sepsis in the postoperative period of cardiac surgery: problem description.
abstract: BACKGROUND
  In spite of the advances in sepsis diagnosis and treatment in the last years, the morbidity and mortality are still high.
  
  
  OBJECTIVE
  To assess the prevalence, in-hospital evolution and prognosis of patients that presented sepsis in the postoperative period of cardiac surgery.
  
  
  METHODS
  This is a prospective study that included patients (n = 7,332) submitted to cardiac surgery (valvular or coronary) between January 1995 and December 2007. The classic criteria of sepsis diagnosis were used to identify the patients that developed such condition and the preoperative comorbidities, in-hospital evolution and prognosis were evaluated.
  
  
  RESULTS
  Sepsis occurred in 29 patients (prevalence = 0.39%). There was a predominance of the male when compared to the female sex (79% vs. 21%). Mean age was 69 +/- 6.5 years. The main preoperative comorbidities were: systemic arterial hypertension (79%), dyslipidemia (48%) and family history of coronary artery disease (38%). The mean Apache score was 18 +/- 7, whereas the Sofa score was 14.2 +/- 3.8. The primary infectious focus was pulmonary in 19 patients (55%). There were 19 positive cultures and the mean IV hydration during the first 24 hours was 1,016 +/- 803 ml. The main complications were acute renal failure (65%), low cardiac output syndrome (55%) and malignant ventricular arrhythmia (55%). Mortality was 79% (23 patients).
  
  
  CONCLUSIONS
  The occurrence of sepsis after cardiac surgery was a rare event; however, its occurrence showed catastrophic clinical outcomes. The high morbidity and mortality showed the need to improve treatment, aiming at patients' better clinical evolution.
authors: Hospital das Clínicas, Universidade Federal de Pernambuco, Recife, PE, Brazil. dinaldo@cardiol.br
authors: Dinaldo Cavalcanti de
authors: DC
authors: Oliveira
authors: João Bosco de
authors: JB
authors: Oliveira Filho
authors: Rogério Ferreira
authors: RF
authors: Silva
authors: Simone Soares
authors: SS
authors: Moura
authors: Diego Janstk
authors: DJ
authors: Silva
authors: Enilton Sergio Tabosa
authors: ES
authors: Egito
authors: Stevan Krieger
authors: SK
authors: Martins
authors: Luis Carlos Bento
authors: LC
authors: Souza
authors: Adib Domingos
authors: AD
authors: Jatene
authors: Leopoldo Soares
authors: LS
authors: Piegas
mesh_terms: D018806:APACHE; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003327:Coronary Disease / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000145:classification / Q000453:epidemiology*; D011184:Postoperative Period; D015995:Prevalence; D011446:Prospective Studies; D018805:Sepsis / Q000453:epidemiology*; D016896:Treatment Outcome