title: Chemical signal amplification in two-dimensional paper networks.
abstract: Two-dimensional paper networks (2DPNs) hold great potential for extending the utility of paper-based chemical and biochemical diagnostics at a cost and ease-of-use that is comparable to conventional lateral flow strips. 2DPNs enable the automated sequential delivery of multiple reagents to a detection region with a single user activation step, and therefore have the potential to extend the processing capabilities of inexpensive paper-based assays with comparable ease of use to conventional lateral flow tests. In this communication, we used a simple 3 inlet 2DPN to perform signal amplification of a colloidal gold label using a gold enhancement solution, thus demonstrating the capability of 2DPNs to perform processes that can improve limits of detection.
authors: Box 355061, Department of Bioengineering,,University of Washington, Seattle, WA, USA; Fax:206-616-3928; Tel: 206-685-9891.
authors: Elain
authors: E
authors: Fu
authors: Peter
authors: P
authors: Kauffman
authors: Barry
authors: B
authors: Lutz
authors: Paul
authors: P
authors: Yager