Autophagy employs a new DAGger against bacteria.
Autophagy can orchestrate innate immune responses to bacterial infection by targeting invading pathogens for lysosomal degradation. In this issue of Cell Host & Microbe, Shahnazari et al. (2010) unveil the role played by the diacylglycerol-PKC pathway in the routing of intracellular Salmonella to autophagy.
Lafont
Frank
F
INSERM U1019-CNRS UMR 8204, Institut Pasteur de Lille, Univ Lille Nord de France 1, F-59019 Lille Cedex, France. frank.lafont@pasteur-lille.fr