[Investigating the toxicity characteristics of Nassarius Sp. in Ningbo City].
OBJECTIVE
To study the type, distribution, the growth and decline of toxins in Nassarius Sp. and the source of toxins to acquire the basis for the control of Nassarius Sp. poisonings.


METHODS
The toxicity of Nassarius Sp. was detected by mouse bioassay. The saxitoxin (STX), gonyau toxin (GTX), and tetrodo toxin (TTX) were detected by ELISA and HPLC.


RESULTS
Sixty-three poisonous Nassarius Sp. were identified in 127 samples collected from long-term monitoring sites. The detection rate was 49.6%. The detection rate of poisonous Nassarius Sp. was different in varies habitats (P < 0.01). The toxicity of Nassarius Sp. reached a peak in 1991 and hit the rock bottom in 1988. The rate of carrying toxins and the toxicity of detected toxins (STX, GTX and TTX) in Nassarius semiplicatus, Nassa succincta A. Adams and Niotha livescens were high.


CONCLUSIONS
The toxins of Nassarius Sp. in Ningbo City were composed of TTX, STX or GTX, or both TTX and STX. The surveillance proved that some toxins present in Nassarius Sp. in Ningbo City. Poisoning could be caused by eating Nassarius Sp.
Xu
Jingye
J
Ningbo Municipal Center for Disease Control and Prevention, Ningbo 315010, China. xujy@nbcdc.org.cn
Xu
Guozhang
G
Ye
Luming
L
Qin
Pinzhang
P
Hu
Danbiao
D
Yan
Peng
P
Jin
Chunguang
C
Yu
Mei
M
D000818:Animals; D001681:Biological Assay / Q000379:methods; D002681:China; D049851:Gastropoda / Q000378:metabolism / Q000472:pathogenicity; D051379:Mice; D008974:Mollusca / Q000378:metabolism* / Q000472:pathogenicity; D012530:Saxitoxin / Q000031:analogs & derivatives* / Q000032:analysis*; D012758:Shellfish; D057096:Shellfish Poisoning; D013779:Tetrodotoxin / Q000032:analysis*
D012530:Saxitoxin; D013779:Tetrodotoxin; C013007:gonyautoxins