Chitosan aerogel: a recyclable, heterogeneous organocatalyst for the asymmetric direct aldol reaction in water.
Aerogel microspheres of chitosan, an abundant biopolymer obtained from marine crustaceans, have been successfully applied to catalyze the asymmetric aldol reaction in water, providing the products in high yields and with good stereoselectivity (up to 93% ee) and recyclability (up to 4 runs). Yields were favourably affected by additives such as DNP and stearic acid.
Ricci
Alfredo
A
Department of Organic Chemistry A. Mangini, University of Bologna, V. Risorgimento 4, 40136 Bologna, Italy. ricci@ms.fci.unibo.it
Bernardi
Luca
L
Gioia
Claudio
C
Vierucci
Simone
S
Robitzer
Mike
M
Quignard
Françoise
F
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D002384:Catalysis; D048271:Chitosan / Q000737:chemistry*; D003445:Crustacea / Q000737:chemistry; D005782:Gels / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000438:Alcohols; D005782:Gels; D014867:Water; D048271:Chitosan