[Research progress on expression and function of Toll-like receptors in dendritic cells].
Dendritic cells (DCs), the most potent antigen-presenting cells, recognize pathogen by Toll-like receptors (TLRs) and serve as the bridge between the innate and the adaptive immune responses. TLRs-mediated signal transduction plays a crucial role in the functional maturation of DCs. This review summarizes the research progress on the expression and function of TLRs in DCs.
Guo
Jia
J
Department of Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China.
Pan
Jian-ping
JP
D003713:Dendritic Cells / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D015398:Signal Transduction; D051193:Toll-Like Receptors / Q000378:metabolism* / Q000502:physiology*
D051193:Toll-Like Receptors