Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes.
The fluorescence spectrum of the homopolymeric double helix poly(dG) x poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC) x poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.
Vayá
Ignacio
I
Laboratoire Francis Perrin, CEA/DSM/IRAMIS/SPAM-CNRS URA 2453, 91191, Gif-sur-Yvette, France.
Changenet-Barret
Pascale
P
Gustavsson
Thomas
T
Zikich
Dragoslav
D
Kotlyar
Alexander B
AB
Markovitsi
Dimitra
D
D020029:Base Pairing; D004247:DNA / Q000737:chemistry*; D011066:Poly C / Q000737:chemistry*; D011068:Poly G / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013816:Thermodynamics; D013997:Time Factors
D011068:Poly G; C023826:poly(dC); C026628:poly(dG); D011066:Poly C; D004247:DNA