Recent advances in recognition elements of food and environmental biosensors: a review.
A sensitive monitoring of contaminants in food and environment, such as chemical compounds, toxins and pathogens, is essential to assess and avoid risks for both, human and environmental health. To accomplish this, there is a high need for sensitive, robust and cost-effective biosensors that make real time and in situ monitoring possible. Due to their high sensitivity, selectivity and versatility, affinity-based biosensors are interesting for monitoring contaminants in food and environment. Antibodies have long been the most popular affinity-based recognition elements, however recently a lot of research effort has been dedicated to the development of novel recognition elements with improved characteristics, like specificity, stability and cost-efficiency. This review discusses three of these innovative affinity-based recognition elements, namely, phages, nucleic acids and molecular imprinted polymers and gives an overview of biosensors for food and environmental applications where these novel affinity-based recognition elements are applied.
Van Dorst
Bieke
B
University of Antwerp, Department of Biology, Laboratory of Ecophysiology, Biochemistry and Toxicology, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Bieke.vandorst@ua.ac.be
Mehta
Jaytry
J
Bekaert
Karen
K
Rouah-Martin
Elsa
E
De Coen
Wim
W
Dubruel
Peter
P
Blust
Ronny
R
Robbens
Johan
J
D001435:Bacteriophages; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D004782:Environmental Health; D004785:Environmental Pollutants / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D054802:Molecular Imprinting; D009696:Nucleic Acids; D019151:Peptide Library; D014159:Transducers
D004785:Environmental Pollutants; D009696:Nucleic Acids; D019151:Peptide Library