title: Trends in frequency and prevalence of oral cancer and oral squamous cell carcinoma in Mexicans. A 20 years retrospective study.
abstract: OBJECTIVE
  To establish the time trends of the frequency and prevalence of oral cavity cancer in regard to age and gender in a 20-years (time period 1989 - 2008) cohort of Mexicans.
  
  
  METHODS
  13,235 head and neck biopsies from the archive of the Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico were revised. The cases with diagnoses of oral cancer were selected. Gender and age at diagnosis was obtained from medical records. The frequency and prevalence of oral cavity cancer and oral squamous cell carcinoma were assessed biannually in regard to the total number of population served by the oral pathology laboratory. The statistical significance of trends was established using the linear logistic regression (curve estimation) test (s 0.05).
  
  
  RESULTS
  298 cases (138 males; 160 females) of oral cancer were included; 167 (92 females; 75 males; female:male ratio: 1.1:1) corresponded to oral squamous cell carcinoma. From 1989 to 2008 the prevalence of oral cancer and oral squamous cell carcinoma increased 200% (s 0.05) and 100% (s 0.000) respectively. The increase of frequency and prevalence was observed in both genders however only in females was significant (s 0.000). We do not identify changes in the age at diagnosis.
  
  
  CONCLUSIONS
  Oral cancer, specifically oral squamous cell carcinoma, has increase in Mexicans females in the last 20 years.
authors: Oral Pathology Laboratory, Postgraduate and Research Division, Dental School, National Autonomous University of México, México, D.F. México. lgaitan@servidor.unam.mx
authors: Luis-Alberto
authors: LA
authors: Gaitán-Cepeda
authors: Adriana-Graciela
authors: AG
authors: Peniche-Becerra
authors: Daniel
authors: D
authors: Quezada-Rivera
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D013997:Time Factors