Immunoinformatics: an integrated scenario.
Genome sequencing of humans and other organisms has led to the accumulation of huge amounts of data, which include immunologically relevant data. A large volume of clinical data has been deposited in several immunological databases and as a result immunoinformatics has emerged as an important field which acts as an intersection between experimental immunology and computational approaches. It not only helps in dealing with the huge amount of data but also plays a role in defining new hypotheses related to immune responses. This article reviews classical immunology, different databases and prediction tools. It also describes applications of immunoinformatics in designing in silico vaccination and immune system modelling. All these efforts save time and reduce cost.
Tomar
Namrata
N
Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India.
De
Rajat K
RK
D000486:Allergy and Immunology / Q000639:trends*; D000818:Animals; D019295:Computational Biology / Q000639:trends*; D016208:Databases, Factual; D006801:Humans; D020407:Internet