title: Levonorgestrel-releasing intrauterine system (LNG-IUS) as an effective treatment option for endometrial hyperplasia: a 15-year follow-up study.
abstract: The levonorgestrel-releasing intrauterine system may represent an effective treatment option in >85% of endometrial hyperplasia cases, but histologic regression during and/or at the end of treatment does not assure stable recovery. We recommend periodic endometrial samplings for at least the first 2 years of follow-up and long-term clinical surveillance thereafter.
authors: Department of Gynecology, Perinatology, and Human Reproduction, University of Florence, Florence, Italy.
authors: Gianfranco
authors: G
authors: Scarselli
authors: Gianni
authors: G
authors: Bargelli
authors: Gian Luigi
authors: GL
authors: Taddei
authors: Mauro
authors: M
authors: Marchionni
authors: Elena
authors: E
authors: Peruzzi
authors: Annalisa
authors: A
authors: Pieralli
authors: Alberto
authors: A
authors: Mattei
authors: Anna Maria
authors: AM
authors: Buccoliero
authors: Massimiliano
authors: M
authors: Fambrini
mesh_terms: D000328:Adult; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D004714:Endometrial Hyperplasia / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D007434:Intrauterine Devices; D016912:Levonorgestrel / Q000008:administration & dosage*; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D003271:Contraceptive Agents, Female; D016912:Levonorgestrel