Brønsted acid differentiated metal catalysis by kinetic discrimination.
A Brønsted acid differentiated metal catalyzed hydrogenation has been developed. A combinatorial variation of chiral triflylamides with achiral metal complexes results in a highly active catalyst for the asymmetric reduction.
Rueping
Magnus
M
RWTH Aachen University, Institute of Organic Chemistry, Landoltweg 1, D-52074 Aachen, Germany. magnus.rueping@rwth-aachen.de
Koenigs
René M
RM
D000143:Acids / Q000737:chemistry*; D000577:Amides / Q000737:chemistry; D002384:Catalysis; D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D007700:Kinetics; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000143:Acids; D000577:Amides; D009942:Organometallic Compounds; D011804:Quinolines; D007495:Iridium