title: Durability of the self-approximating translumenal access technique (STAT) for potential use in natural orifice translumenal surgery (NOTES).
abstract: BACKGROUND
  The self-approximating translumenal access technique (STAT) has been shown to provide a safe and reliable means of abdominal access for natural orifice translumenal endoscopic surgery (NOTES). However, the feasibility of using STAT for translumenal organ resection is unknown. This study aimed to evaluate the technical performance of organ resection using STAT, the integrity of the STAT gastric tunnel after organ resection, and the postoperative morbidity of organ resection using STAT.
  
  
  METHODS
  In this study, 14 domestic swine underwent transgastric organ resection (7 cholecystectomies, 7 uterine horn resections) followed by sequential removal of two different sizes of standardized specimens. Evaluation of operative injury to the tunnel and difficulty of specimen extraction was performed. After 2 weeks of observation, necropsy was performed for evaluation and documentation of gross findings.
  
  
  RESULTS
  The mean operating room time (intubation recovery) was 4.1 h. A tunnel with a mean length of 12 cm and a mean width of 4 cm was created. The tunnel remained fully intact in 14 of 14 animals after organ resection, in 13 of 13 animals after balloon extraction, and in 12 of 14 animals after rigid specimen extraction (1 clinically significant tear occurred). Postoperatively, all the animals gained weight appropriately. Necropsy findings included adhesions (n = 4), bile leak (n = 2), minor lap-port abscess (n = 1), and ventral hernia (n = 1).
  
  
  CONCLUSIONS
  Although this study was a limited, prospective, animal survival study without a control arm, it again indicates that STAT allows safe abdominal access, a reliable means of closure, and directed endoscope positioning. Although one significant mucosal tear did occur, this study suggests STAT will tolerate the mechanical forces of peroral transgastric procedures provided the organ resected is small to moderate in size (<8 × 3 cm).
authors: Division of Gastroenterology/Hepatology, Penn State Hershey Medical Center, Hershey, PA, USA. mmoyer@psu.edu
authors: Matthew T
authors: MT
authors: Moyer
authors: Eric M
authors: EM
authors: Pauli
authors: Jegan
authors: J
authors: Gopal
authors: Abraham
authors: A
authors: Mathew
authors: Randy S
authors: RS
authors: Haluck
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology / Q000473:pathology; D000818:Animals; D002763:Cholecystectomy / Q000009:adverse effects / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D005753:Gastric Mucosa / Q000293:injuries; D006555:Hernia, Ventral / Q000209:etiology / Q000473:pathology; D015907:Hysteroscopy / Q000009:adverse effects / Q000379:methods*; D057605:Natural Orifice Endoscopic Surgery / Q000009:adverse effects / Q000379:methods*; D011028:Pneumoperitoneum, Artificial; D011446:Prospective Studies; D013270:Stomach; D034421:Sus scrofa; D013552:Swine; D000267:Tissue Adhesions / Q000209:etiology / Q000473:pathology