Long-chain O-ascarosyl-alkanediols are constitutive components of Caenorhabditis elegans but do not induce dauer larva formation.
Two long-chain ascarosides, O-ascarosylnonacosane-2,28-diol and O-ascarosyluntriacontane-2,30-diol, were isolated from Caenorhabditis elegans and detected in all developmental stages of the worm. The long-chain ascarosides were shown to be minor lipid components, and it was also shown that they do not induce dauer larva formation.
Zagoriy
Vyacheslav
V
Max-Planck Institute for Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden. zagoriy@mpi-cbg.de
Matyash
Vitaliy
V
Kurzchalia
Teymuras
T
D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry* / Q000187:drug effects / Q000254:growth & development; D002855:Chromatography, Thin Layer; D006017:Glycolipids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D008956:Models, Chemical
D006017:Glycolipids; C554535:O-ascarosylnonacosane-2,28-diol; C554536:O-ascarosyluntriacontane-2,30-diol