title: Evaluation of BBL CHROMagar VanRE for detection of vancomycin-resistant Enterococci in rectal swab specimens.
abstract: A study was performed on 517 surveillance rectal swabs to evaluate a selective and differential chromogenic medium, the BBL CHROMagar VanRE (CVRE), which enables recovery and identification of VanA- and VanB-containing Enterococcus faecium (ENFM) and Enterococcus faecalis (ENFS) isolates. Compared to BBL Enterococcosel agar, a bile-esculin-azide-vancomycin (BEAV) agar, the initial overall sensitivity, specificity, and positive and negative predictive values of CVRE for the detection of vancomycin-resistant ENFM and ENFS were 99.1% and 94.8% and 84.2% and 99.7%, respectively. Among our patient population, more vancomycin-resistant enterococci (VRE) were recovered with CVRE than BEAV.
authors.affiliation: Division of Medical Microbiology, Department of Pathology, the Johns Hopkins University School of Medicine and the Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Stamper
authors.forename: Stephanie
authors.initials: S
authors.lastname: Shulder
authors.forename: Pearl
authors.initials: P
authors.lastname: Bekalo
authors.forename: Deepika
authors.initials: D
authors.lastname: Manandhar
authors.forename: Tracy L
authors.initials: TL
authors.lastname: Ross
authors.forename: Sharon
authors.initials: S
authors.lastname: Speser
authors.forename: Julie
authors.initials: J
authors.lastname: Kingery
authors.forename: Karen C
authors.initials: KC
authors.lastname: Carroll
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001386:Azides / Q000378:metabolism; D001646:Bile / Q000378:metabolism; D003470:Culture Media / Q000737:chemistry*; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000302:isolation & purification; D016984:Enterococcus faecium / Q000187:drug effects* / Q000302:isolation & purification; D004929:Esculin / Q000378:metabolism; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D011237:Predictive Value of Tests; D012007:Rectum / Q000382:microbiology*; D012680:Sensitivity and Specificity; D014640:Vancomycin / Q000494:pharmacology*; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D001386:Azides; D003470:Culture Media; D004929:Esculin; D014640:Vancomycin