title: Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma: A First Case Report and Review of the Literature.
abstract: Intrathoracic endotracheal metastasis from a very distant site is extremely rare. We report the first case of such a disease in a 68-year-old man with nasopharyngeal carcinoma who presented with a cough and hemoptysis 34 months after finishing radiotherapy. Prior to tracheal metastasis, he developed a solitary metastasis in the lung and underwent chemotherapy followed by radiotherapy. Computed tomography showed the presence of an enlarged lymph node in the para-aortic arch. Fiberoptic bronchoscopy revealed an endotracheal tumor 1 cm above the carina. Histological and immunohistochemical analyses confirmed its nasopharyngeal origin. He was treated with conventional radiotherapy and three-dimensional conformal radiotherapy; complete tumor remission was achieved. He died of nonmalignant disease with no signs of tumor recurrence 2 years after treatment completion. Radiotherapy may be an appropriate management approach to achieve long-term tumor control for this disease.
authors.affiliation: Department of Radiation Oncology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning City, P.R. China.
authors.forename: Heming
authors.initials: H
authors.lastname: Lu
authors.forename: Jiaxin
authors.initials: J
authors.lastname: Chen
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Xie
authors.forename: Jinjian
authors.initials: J
authors.lastname: Cheng
authors.forename: Yanrong
authors.initials: Y
authors.lastname: Hao
authors.forename: Luxing
authors.initials: L
authors.lastname: Peng
authors.forename: Qiang
authors.initials: Q
authors.lastname: Pang
authors.forename: Shan
authors.initials: S
authors.lastname: Deng
authors.forename: Junzhao
authors.initials: J
authors.lastname: Gu
authors.forename: Jian
authors.initials: J
authors.lastname: Qin
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Lu