[Effect of hyperosmolar solutions on partial pressure of oxygen in arterial blood].
The study was undertaken to define the effect of hyperosmolar solutions on arterial blood oxygen levels. Analysis of arterial blood oxygenation after hyperosmolar solution infusions revealed a drop in partial pressure of oxygen (132.14 +/- 70.36, 120.0 +/- 66.48, and 119.24 +/- 70.10 mm Hg). At the same time there was a reduction in the extravascular lung water index (p < 0.05) as compared with the baseline values (7.93 +/- 2.17, 7.31 +/- 1.7), and Z62 +/- 1.99 ml/kg), respectively. This effect is particularly marked in a group of patients in whom the arterial blood content of oxygen is in the lower normal range. To evaluate and eliminate the above effect in reducing the arterial blood level, it is necessary to estimate respiratory indices during hyperosmolar solution infusion.
Davydova
L A
LA
Gutnikov
A I
AI
Evdokimov
E A
EA
Klochkov
O E
OE
Karpenko
V V
VV
D000328:Adult; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D019586:Intracranial Hypertension / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D008991:Monitoring, Physiologic; D009994:Osmolar Concentration; D010100:Oxygen / Q000097:blood*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage* / Q000737:chemistry; D012964:Sodium / Q000097:blood; D013815:Thermodilution; D016896:Treatment Outcome
D012462:Saline Solution, Hypertonic; D002245:Carbon Dioxide; D012964:Sodium; D010100:Oxygen