Psychiatric symptoms associated with focal hand dystonia.
Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.
Voon
Valerie
V
Behavioral and Clinical Neurosciences Institute, University of Cambridge, Cambridge, UK. voonv@gmail.com
Butler
Tracy R
TR
Ekanayake
Vindhya
V
Gallea
Cecile
C
Ameli
Rezvan
R
Murphy
Dennis L
DL
Hallett
Mark
M
D000328:Adult; D003863:Depression / Q000209:etiology*; D020821:Dystonic Disorders / Q000150:complications* / Q000473:pathology*; D005260:Female; D006225:Hand / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000209:etiology*; D011569:Psychiatric Status Rating Scales