title: Long-term increase of fat mass after a four week intervention with fast food based hyper-alimentation and limitation of physical activity.
abstract: BACKGROUND
  A sedentary lifestyle and increased consumption of energy dense food have become more common in many parts of the world. The aim of this study was to study long term effects on body composition after a four week intervention with fast food based hyper-alimentation and limited physical activity in young normal weight subjects.
  
  
  METHODS
  Eighteen subjects, mean age 26 (6.6) years, increased their energy intake with in average 70% and physical activity were not to exceed 5000 steps/day. Body composition was measured by Dual energy x-ray (DXA) at baseline, after the intervention and after 12 months. A matched control group was also included. ANOVA and Student's paired and unpaired t-test were used.
  
  
  RESULTS
  During the intervention body weight increased with 6.4 (2.8) kg and DXA measurements showed increases of both fat free mass and fat mass. Six months after the intervention the subjects had lost most of the weight gain, - 4.7 (3.1) kg. Twelve months after the intervention body weight had increased with 1.5 (2.4) kg compared to baseline (p = 0.018). DXA measurements at 12 months showed unchanged fat free mass compared to baseline but higher fat mass, + 1.4 (1.9) kg (p = 0.01). After 2.5 years the increase of body weight was 3.1 (4.0) kg (p = 0.01) while there was no change in controls compared to baseline, + 0.1(2.5) kg (p = 0.88).
  
  
  CONCLUSIONS
  One year after a short term intervention with increased fast food based hyper-alimentation there was an increase of fat mass but unchanged fat free mass. As the change of fat mass was larger than expected from prospective epidemiological studies and as there was no increase of body weight in controls it raises the issue whether there is a long-term effect to increase fat mass of a short period of hyper-alimentation.
authors.affiliation: Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, SE 58185 Linköping, Sweden. asa.ernersson@liu.se.
authors.forename: Asa
authors.initials: A
authors.lastname: Ernersson
authors.forename: Fredrik H
authors.initials: FH
authors.lastname: Nystrom
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Lindström