title: Efficiency of fine-needle aspiration compared with other sampling techniques for laboratory diagnosis of Buruli ulcer disease.
abstract: In accordance with recent WHO recommendations, this study evaluates the sensitivities of PCR and microscopy for fine-needle aspiration (FNA) versus techniques involving swabs and punch biopsy specimens and suggests that FNA can replace punch biopsies for nonulcerative lesions and may serve as an alternative for ulcerative lesions in cases where scarred edges prevent the collection of swabs.
authors.affiliation: Department of Infectious Diseases and Tropical Medicine (DITM), University Hospital, Ludwig-Maximilians University of Munich, Munich, Germany. herbinger@lrz.uni-muenchen.de
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Herbinger
authors.forename: Marcus
authors.initials: M
authors.lastname: Beissner
authors.forename: Kristina
authors.initials: K
authors.lastname: Huber
authors.forename: Nana-Yaa
authors.initials: NY
authors.lastname: Awua-Boateng
authors.forename: Jörg
authors.initials: J
authors.lastname: Nitschke
authors.forename: William
authors.initials: W
authors.lastname: Thompson
authors.forename: Erasmus
authors.initials: E
authors.lastname: Klutse
authors.forename: Pius
authors.initials: P
authors.lastname: Agbenorku
authors.forename: Awovi
authors.initials: A
authors.lastname: Assiobo
authors.forename: Ebekalisai
authors.initials: E
authors.lastname: Piten
authors.forename: Franz
authors.initials: F
authors.lastname: Wiedemann
authors.forename: Erna
authors.initials: E
authors.lastname: Fleischmann
authors.forename: Kerstin
authors.initials: K
authors.lastname: Helfrich
authors.forename: Ohene
authors.initials: O
authors.lastname: Adjei
authors.forename: Thomas
authors.initials: T
authors.lastname: Löscher
authors.forename: Gisela
authors.initials: G
authors.lastname: Bretzel
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D044963:Biopsy, Fine-Needle / Q000379:methods*; D054312:Buruli Ulcer / Q000175:diagnosis; D006801:Humans; D008853:Microscopy / Q000379:methods; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods*