title: [Which brakes upon severe dementia clinical research?].
abstract: Publications devoted to severe dementia remain limited, whereas several authors underline the need to carry on clinical research in the field. The aim of this paper is to analyze the various technical, psychological and sociological factors that slow down the development of clinical research in severe dementia. To reduce these obstacles seems of main interest considering the economic, medical and human issues related to the severe stage of dementia.
authors.affiliation: Service de médecine gériatrique, CHU de Rennes. anne-sophie.gillioz@chu-rennes.fr
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Gillioz
authors.forename: Hélène
authors.initials: H
authors.lastname: Villars
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Malo
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Silvestre
authors.forename: Pierre
authors.initials: P
authors.lastname: Jouanny
mesh_terms: D000203:Activities of Daily Living / Q000145:classification; D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D035843:Biomedical Research / Q000639:trends*; D017028:Caregivers / Q000523:psychology; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D003131:Combined Modality Therapy; D017281:Cost of Illness; D005544:Forecasting; D006301:Health Services Needs and Demand / Q000639:trends; D006801:Humans; D009483:Neuropsychological Tests; D010348:Patient Care Team / Q000639:trends; D011287:Prejudice; D012934:Social Isolation; D016896:Treatment Outcome
chemical_list: D018680:Cholinergic Antagonists