title: Analysis of BCR-ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype.
authors.forename: H
authors.initials: H
authors.lastname: Grant
authors.forename: X
authors.initials: X
authors.lastname: Jiang
authors.forename: J
authors.initials: J
authors.lastname: Stebbing
authors.forename: L
authors.initials: L
authors.lastname: Foroni
authors.forename: C
authors.initials: C
authors.lastname: Craddock
authors.forename: M
authors.initials: M
authors.lastname: Griffiths
authors.forename: R E
authors.initials: RE
authors.lastname: Clark
authors.forename: S
authors.initials: S
authors.lastname: O'Brien
authors.forename: J S
authors.initials: JS
authors.lastname: Khorashad
authors.forename: G
authors.initials: G
authors.lastname: Gerrard
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: J A E
authors.initials: JA
authors.lastname: Irving
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Karran
authors.forename: M J S
authors.initials: MJ
authors.lastname: Dyer
authors.forename: D
authors.initials: D
authors.lastname: Forrest
authors.forename: K
authors.initials: K
authors.lastname: Page
authors.forename: C J
authors.initials: CJ
authors.lastname: Eaves
authors.forename: A
authors.initials: A
authors.lastname: Woolfson
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D016044:Fusion Proteins, bcr-abl / Q000235:genetics*; D015894:Genome, Human; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008962:Models, Theoretical; D010641:Phenotype; D010879:Piperazines / Q000627:therapeutic use; D017354:Point Mutation / Q000235:genetics*; D011379:Prognosis; D017434:Protein Structure, Tertiary; D011743:Pyrimidines / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D016044:Fusion Proteins, bcr-abl