Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives.
Substituted bicyclo[5.3.0]azulene compounds are synthesized by intermolecular [8+2] cycloaddition reactions of lactone 1 with vinyl ethers-acetal decomposition products-are described. The reactions were found to be temperature and solvent dependent.
Pham
Wellington
W
Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.
Weissleder
Ralph
R
Tung
Ching-Hsuan
CH