New lupane-type triterpenoid saponins from leaves of Oplopanax horridus (Devil's Club).
Two new lupane type saponins, along with one known saponin were isolated from leaves of Oplopanax horridus (Devil's Club). The structures of the two new compounds were elucidated as 3alpha-hydroxy-lup-20(29)-ene-23, 28-dioic acid-3-O-beta-D-glucopyranoside (2) and 24-nor-3-oxo-lup-20(29)-en-28-oic acid-28-O-alpha-L-rhamnopyranosyl(1''' --> 4")-beta-D-glucopyranosyl(1" --> 6')-beta-D-glucopyranoside (3) on the basis of spectroscopic analysis and chemical evidence. The known compound was identified as 3alpha-hydroxy-lup-20(29)-ene-23, 28-dioic acid (1) by comparison of its spectral data with those reported. Compound 1 was isolated for the first time from the title plant.
Liu
Pei-Pei
PP
College of Pharmacy, Liaoning University of Traditional Chinese Medicine, 77 Life one Road, Dalian Economic and Technical Development Zone, Dalian 116600, China.
Li
Mo
M
Kang
Ting-Guo
TG
Dou
De-Qiang
DQ
Smith
David C
DC
D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028002:Oplopanax / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*; D053978:Pentacyclic Triterpenes
D014315:Triterpenes; C480546:lupane; D053978:Pentacyclic Triterpenes