title: Fibroma of the medial canthal area: a case report.
abstract: A 47-year-old women presented with a mass on the right medial canthal area for 10 years. On examination, an 18 × 12-mm sized, hard, unmovable subcutaneous mass was palpated. The tear meniscus was high, but the lacrimal outflow system was patent when irrigated. The mass was surgically excised. It was well-demarcated with a whitish pearl-like appearance and located between the orbicularis muscle and the anterior lacrimal crest. A silicone tube was intubated simultaneously. The microscopic examination of the specimen revealed dense collagen with scattered fibroblasts without mitosis or atypism, and stained positively for vimentin and negatively for S-100 and CD 34. Based on these findings, the lesion was diagnosed as a fibroma. No sign of recurrence was observed over 6 months of follow up. Although rare, fibroma should be included in the differential diagnosis of medial canthal tumors. Complete surgical excision offers a curative method of management.
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Min
authors.initials: M
authors.lastname: Joung Lee
authors.forename: Sang
authors.initials: S
authors.lastname: Khwarg
mesh_terms: D018952:Antigens, CD34 / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D005142:Eyelid Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D005350:Fibroma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007440:Intubation; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008875:Middle Aged; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014746:Vimentin / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D009418:S100 Proteins; D014746:Vimentin; D003094:Collagen