Cell interaction with nanopatterned surface of implants.
Metals such as titanium and alloys are commonly used for manufacturing orthopedic and dental implants because their surface properties provide a biocompatible interface with peri-implant tissues. Strategies for modifying the nature of this interface frequently involve changes to the surface at the nanometer level, thereby affecting protein adsorption, cell-substrate interactions and tissue development. Recent methods to control these biological interactions at the nanometer scale on the surface of implants are reviewed. Future strategies to control peri-implant tissue healing are also discussed.
Lavenus
Sandrine
S
Faculty of Medicine, Inserm, U957, LPRO, University of Nantes, 1 Rue Gaston Veil, 44042 Nantes cedex1, France.
Ricquier
Jean-Charles
JC
Louarn
Guy
G
Layrolle
Pierre
P
D000818:Animals; D001672:Biocompatible Materials; D006801:Humans; D049329:Nanostructures; D019736:Prostheses and Implants
D001672:Biocompatible Materials