title: Cell interaction with nanopatterned surface of implants.
abstract: Metals such as titanium and alloys are commonly used for manufacturing orthopedic and dental implants because their surface properties provide a biocompatible interface with peri-implant tissues. Strategies for modifying the nature of this interface frequently involve changes to the surface at the nanometer level, thereby affecting protein adsorption, cell-substrate interactions and tissue development. Recent methods to control these biological interactions at the nanometer scale on the surface of implants are reviewed. Future strategies to control peri-implant tissue healing are also discussed.
authors.affiliation: Faculty of Medicine, Inserm, U957, LPRO, University of Nantes, 1 Rue Gaston Veil, 44042 Nantes cedex1, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Lavenus
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Ricquier
authors.forename: Guy
authors.initials: G
authors.lastname: Louarn
authors.forename: Pierre
authors.initials: P
authors.lastname: Layrolle
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D006801:Humans; D049329:Nanostructures; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials