title: Transmission dynamics of an emerging infectious disease in wildlife through host reproductive cycles.
abstract: Emerging infectious diseases are major threats to wildlife populations. To enhance our understanding of the dynamics of these diseases, we investigated how host reproductive behavior and seasonal temperature variation drive transmission of infections among wild hosts, using the model system of cyprinid herpesvirus 3 (CyHV-3) disease in common carp. Our main findings were as follows: (1) a seroprevalence survey showed that CyHV-3 infection occurred mostly in adult hosts, (2) a quantitative assay for CyHV-3 in a host population demonstrated that CyHV-3 was most abundant in the spring when host reproduction occurred and water temperature increased simultaneously and (3) an analysis of the dynamics of CyHV-3 in water revealed that CyHV-3 concentration increased markedly in breeding habitats during host group mating. These results indicate that breeding habitats can become hot spots for transmission of infectious diseases if hosts aggregate for mating and the activation of pathogens occurs during the host breeding season.
authors.affiliation: Research Institute for Humanity and Nature, Kyoto, Japan. c-uchii@mail.ecc.u-tokyo.ac.jp
authors.forename: Kimiko
authors.initials: K
authors.lastname: Uchii
authors.forename: Arndt
authors.initials: A
authors.lastname: Telschow
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Minamoto
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yamanaka
authors.forename: Mie N
authors.initials: MN
authors.lastname: Honjo
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Matsui
authors.forename: Zen'ichiro
authors.initials: Z
authors.lastname: Kawabata
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002347:Carps; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000635:transmission*; D005393:Fish Diseases / Q000453:epidemiology / Q000635:transmission*; D005766:Gastrointestinal Contents / Q000821:virology; D006564:Herpesviridae / Q000302:isolation & purification / Q000502:physiology; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000635:transmission*; D012098:Reproduction / Q000502:physiology*; D012621:Seasons; D012623:Seawater / Q000821:virology; D016036:Seroepidemiologic Studies; D012726:Sexual Behavior, Animal / Q000502:physiology; D013696:Temperature
chemical_list: D000914:Antibodies, Viral