title: [Biologically active additives in health prophylaxis of medical workers].
abstract: The aim of the investigation was to use the biologically active additive (BAD) Kalifen to prevent metabolic disturbances in medical workers during their occupational activity. Female physicians aged 40-50 years were examined. Group 1 (control) included 20 age-matched healthy female donors. Group 2 comprised 27 female physicians (anesthesiologists and surgeons) daily exposed to stresses (chemical, psychoemotional, work-related, etc.) who were asked after blood biochemical tests to daily take the BAD Kalifen in a dose of 2.5 ml after a meal (they made up Group 3), which is equal to the daily prophylactic dose in 100 mg of total polyphenols. The plasma tested before an experiment showed hypertriglyceridemia and hypercholesterolemia, suppressed hepatic etherifying function, imbalance of the fractional content of phospholipids, exhaustion of the antioxidative system, increased lipid peroxidation, and impaired erythrocytic membrane permeability. The prophylactic use of the BAD Kalifen eliminates stress-induced metabolic disturbances and increases occupational and biological longevity in the able-bodied population.
authors.forename: N F
authors.initials: NF
authors.lastname: Kushnerova
authors.forename: S E
authors.initials: SE
authors.lastname: Fomenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Rakhmanin
authors.forename: L N
authors.initials: LN
authors.lastname: Lesnikova
authors.forename: V G
authors.initials: VG
authors.lastname: Sprygin
authors.forename: T V
authors.initials: TV
authors.lastname: Kushnerova
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Merzliakov
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000502:physiology; D019587:Dietary Supplements; D005260:Female; D005419:Flavonoids / Q000008:administration & dosage; D006801:Humans; D006937:Hypercholesterolemia; D006943:Hyperglycemia; D015228:Hypertriglyceridemia; D015227:Lipid Peroxidation; D008875:Middle Aged; D010636:Phenols / Q000008:administration & dosage; D010822:Physicians, Women; D059808:Polyphenols
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D059808:Polyphenols