title: THERAPEUTIC PERSPECTIVES ON THE COMBINATION OF ALPHA-LIPOIC ACID AND VITAMIN E.
abstract: Alpha-lipoic acid and vitamin E have synergistic effects, as determined in models of oxidant radical lesions. This review summarizes recent findings showing that the combination of alpha-lipoic acid plus vitamin E has beneficial effects in reducing oxidative damage in ischemic or other oxidation-related pathological events. Both antioxidants are common in the normal human diet and side effects are very rare. Therefore, alpha-lipoic acid and vitamin E can counteract oxidative processes and could have an important role in clinical medicine.
authors.affiliation: Neurosurgery & Program in Developmental and Stem Cell Biology. University of California, San Francisco. San Francisco, CA 94143.
authors.forename: Oscar
authors.initials: O
authors.lastname: Gonzalez-Perez
authors.forename: Rocio E
authors.initials: RE
authors.lastname: Gonzalez-Castaneda