title: ICPS: an integrative cancer profiler system.
abstract: Founded upon the database of 570 public signatures, ICPS is a web-based application to obtain biomarker profiles among 11 common cancers by integrating genomic alterations with transcription signatures on the basis of a previously developed integrative pipeline. ICPS supports both public data and user's in-house data, and performs meta-analysis at a cancer subtype level by combining heterogeneous datasets. Finally, ICPS returns the robust gene signature containing potential cancer biomarkers that may be useful to carcinogenesis study and clinical cancer diagnosis.
  
  
  BACKGROUND
  http://server.bioicps.org
  
  
  BACKGROUND
  zhxy@mail.tsinghua.edu.cn; zxy-dcs@mail.tsinghua.edu.cn
authors.affiliation: State Key Laboratory of Intelligent Technology and Systems, Tsinghua National Laboratory for Information Science and Technology, Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China. zhxy@mail.tsinghua.edu.cn
authors.forename: Xin-yu
authors.initials: XY
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Shi
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Feng
authors.initials: F
authors.lastname: Tian
authors.forename: Hai-tao
authors.initials: HT
authors.lastname: Zhao
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Miao
authors.forename: Ming-lie
authors.initials: ML
authors.lastname: Huang
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Zhu
mesh_terms: D015415:Biomarkers / Q000032:analysis; D030541:Databases, Genetic; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D020407:Internet; D015201:Meta-Analysis as Topic; D009369:Neoplasms / Q000235:genetics*; D012984:Software
chemical_list: D015415:Biomarkers