title: Aerobic exercise training-induced decrease in plasma visfatin and insulin resistance in obese female adolescents.
abstract: The purpose of this study was to assess differences in the levels of plasma visfatin among female adolescents and changes in plasma visfatin and insulin resistance in obese female adolescents after 12 wk of aerobic exercise training. Twenty normal-weight female students (body-mass index [BMI] < 22.9 kg/m² and body fat ≤ 29.9) and 18 obese female students (BMI ≥ 25 kg/ m² and body fat ≥ 30%) participated in this study. Eleven obese students were assigned to an exercise group and completed a 12-wk aerobic exercise-training program that included four 40- to 50-min sessions per wk with an energy expenditure of 300-400 kcal/d. Seven obese students were assigned to a control group that received no exercise sessions or dietary restriction. The plasma visfatin levels of obese female adolescents were significantly higher (p < .05) than those of the normal-weight female adolescents. The plasma visfatin levels (294.00 ± 124.74 ng/ml to 185.55 ± 67.30 ng/ml, p < .01) and insulin resistance (p < .05) were significantly reduced after 12 wk of aerobic exercise. The results suggest that aerobic exercise resulting in an energy expenditure of 1,200-1,600 kcal/wk for 12 wk decreases plasma visfatin and insulin resistance in obese female adolescents.
authors.affiliation: Institute of Sports Science, Seoul National University, Seoul, Korea.
authors.forename: Kyu-Jin
authors.initials: KJ
authors.lastname: Lee
authors.forename: Yun-A
authors.initials: YA
authors.lastname: Shin
authors.forename: Kyoung-Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Tae-Won
authors.initials: TW
authors.lastname: Jun
authors.forename: Wook
authors.initials: W
authors.lastname: Song
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D016022:Case-Control Studies; D016207:Cytokines / Q000097:blood*; D004734:Energy Metabolism / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D054409:Nicotinamide Phosphoribosyltransferase / Q000097:blood*; D009765:Obesity / Q000378:metabolism*; D013851:Thinness / Q000378:metabolism; D015431:Weight Loss / Q000502:physiology
chemical_list: D001786:Blood Glucose; D016207:Cytokines; D054409:Nicotinamide Phosphoribosyltransferase; C085455:nicotinamide phosphoribosyltransferase, human