TFInfer: a tool for probabilistic inference of transcription factor activities.
CONCLUSIONS
TFInfer is a novel open access, standalone tool for genome-wide inference of transcription factor activities from gene expression data. Based on an earlier MATLAB version, the software has now been extended in a number of ways. It has been significantly optimised in terms of performance, and it was given novel functionality, by allowing the user to model both time series and data from multiple independent conditions. With a full documentation and intuitive graphical user interface, together with an in-built data base of yeast and Escherichia coli transcription factors, the software does not require any mathematical or computational expertise to be used effectively.


BACKGROUND
http://homepages.inf.ed.ac.uk/gsanguin/TFInfer.html


BACKGROUND
gsanguin@staffmail.ed.ac.uk


BACKGROUND
Supplementary data are available at Bioinformatics online.
Asif
H M Shahzad
HM
School of Informatics, University of Edinburgh, 10 Crichton Street, Edinburgh EH8 9AB, UK.
Rolfe
Matthew D
MD
Green
Jeff
J
Lawrence
Neil D
ND
Rattray
Magnus
M
Sanguinetti
Guido
G
D019295:Computational Biology; D016208:Databases, Factual; D004926:Escherichia coli / Q000378:metabolism; D015870:Gene Expression; D015233:Models, Statistical; D012984:Software; D014157:Transcription Factors / Q000737:chemistry* / Q000378:metabolism; D015003:Yeasts / Q000378:metabolism
D014157:Transcription Factors