title: [The value of mediastinoscopy in the staging of lung cancer with clinical N2 disease.].
abstract: BACKGROUND
  To determine the value of mediastinoscopy in the mediastinal staging of lung cancer with clinical N2 disease.
  
  
  METHODS
  We retrospectively reviewed 87 patients received mediastinoscopy for known or suspected lung cancer, including 83 cervical mediastinoscopies and 4 parasternal mediastinoscopies. All patients were staged clinical N2 for enlarged ipsilateral mediastinal and/or subcarinal lymph nodes (short axis > 1.0 cm) on computed tomography scan.
  
  
  RESULTS
  Of the 87 patients, 61 cases proved N2 disease on mediastinoscopy. The other 26 mediastinoscopy-negative patients underwent thoracotomy for lung resection and mediastinal lymph node dissection in the same operative session. Final pathologic N staging were consistent for mediastinoscopic sampling and surgical dissection in 24 patients. N2 disease was found in 2 patients (false-negative of mediastinoscopy). The sensitivity, specificity, and accuracy of mediastinoscopy were 96.8%, 100%, and 97.7%, respectively. There was no mortality and only 1 complication (1.1%) for all 87 mediastinoscopic procedures.
  
  
  CONCLUSIONS
  Mediastinoscopy is a highly effective and safe procedure for the mediastinal staging of lung cancer with clinical N2 disease.
authors.affiliation: Department of Thoracic Surgery, People's Hospital, Peking University, Beijing 100044, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhao
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Li
authors.forename: Guanchao
authors.initials: G
authors.lastname: Jiang
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Yanguo
authors.initials: Y
authors.lastname: Liu
authors.forename: Zuli
authors.initials: Z
authors.lastname: Zhou