ATP-modulated ionic transport through synthetic nanochannels.
Here, we demonstrate an anion controlled molecular gate based on synthetic ion channels modified with polyethyleneimine. For single conical nanochannels, addition of ATP leads to significant decrease in the rectified ion flux, representing the closure of the ionic gate. Complementary experiments performed with nanoporous membranes show that the flux of charged dye (NDS(2-)) through a cylindrical nanochannel array diminishes by the co-addition of ATP in the analyte solution.
Ali
Mubarak
M
Technische Universität Darmstadt, Fachgebiet Materialanalytik, Petersenstr. 23, D-64287 Darmstadt, Germany. m.ali@gsi.de
Nguyen
Quoc Hung
QH
Neumann
Reinhard
R
Ensinger
Wolfgang
W
D000255:Adenosine Triphosphate / Q000737:chemistry*; D004573:Electrolytes; D017136:Ion Transport; D007477:Ions / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry
D004573:Electrolytes; D007477:Ions; D000255:Adenosine Triphosphate; D011094:Polyethyleneimine