title: Antenatal embolization of a large chorioangioma by percutaneous Glubran 2 injection.
abstract: We describe a case of a large chorioangioma diagnosed at 18 weeks' gestation. Because of advanced fetal heart failure at 23 weeks' gestation, embolization of the chorioangioma's vessels was performed by percutaneous injection of Glubran 2 surgical glue. There was no immediate secondary effect of treatment. Devascularization was complete and durable. Signs of fetal cardiac failure normalized after 1 month and a healthy infant was delivered at 38 weeks. To our knowledge this is the first reported case of perinatal survival after successful embolization of a chorioangioma using tissue glue.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital Erasme, Brussels, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Gajewska
authors.forename: A
authors.initials: A
authors.lastname: Herinckx
authors.forename: A
authors.initials: A
authors.lastname: Holoye
authors.forename: N
authors.initials: N
authors.lastname: D'Haene
authors.forename: A
authors.initials: A
authors.lastname: Massez
authors.forename: M
authors.initials: M
authors.lastname: Cassart
authors.forename: M
authors.initials: M
authors.lastname: Van Rysselberge
authors.forename: C
authors.initials: C
authors.lastname: Donner
mesh_terms: D000328:Adult; D003487:Cyanoacrylates / Q000008:administration & dosage*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005315:Fetal Diseases / Q000628:therapy; D005865:Gestational Age; D006333:Heart Failure / Q000628:therapy; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging / Q000628:therapy*; D011256:Pregnancy Outcome; D014014:Tissue Adhesives / Q000008:administration & dosage*; D014463:Ultrasonography
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C421461:glubran 2