title: Complete Radiologic Response in an Anaplastic Oligodendroglioma Treated with Temozolomide and Bevacizumab.
abstract: In this case report, we describe a rare case of a 32-year-old man who presented a highly aggressive, fast growing anaplastic oligodendroglioma five years after being treated with whole brain radiotherapy for a CNS recurrence of a lymphoblastic lymphoma. Initially, the patient was submitted to a surgical intervention and partial tumor resection, which allowed us to establish the pathologic diagnosis and the presence of a 1p deletion. Shortly after the operation the tumor grew back, exerting important mass effect. Since no radiation therapy or surgery could be used and the patient faced a critical condition, chemotherapy was started with a combination of temozolomide and bevacizumab. Immediately after the first cycle a marked clinical and radiological improvement was documented.
authors.affiliation: Centro de Oncologia, Hospital Sírio-Libanês, São Paulo, Brazil.
authors.forename: Artur
authors.initials: A
authors.lastname: Katz
authors.forename: Aknar
authors.initials: A
authors.lastname: Calabrich
authors.forename: Gustavo
authors.initials: G
authors.lastname: Dos Santos Fernandes
authors.forename: Yana Augusta
authors.initials: YA
authors.lastname: Sakis Novis