title: Myogenesis and molecules - insights from zebrafish Danio rerio.
abstract: Myogenesis is a fundamental process governing the formation of muscle in multicellular organisms. Recent studies in zebrafish Danio rerio have described the molecular events occurring during embryonic morphogenesis and have thus greatly clarified this process, helping to distinguish between the events that give rise to fast v. slow muscle. Coupled with the well-known Hedgehog signalling cascade and a wide variety of cellular processes during early development, the continual research on D. rerio slow muscle precursors has provided novel insights into their cellular behaviours in this organism. Similarly, analyses on fast muscle precursors have provided knowledge of the behaviour of a sub-set of epitheloid cells residing in the anterior domain of somites. Additionally, the findings by various groups on the roles of several molecules in somitic myogenesis have been clarified in the past year. In this study, the authors briefly review the current trends in the field of research of D. rerio trunk myogenesis.
authors.affiliation: Laboratory of Developmental Signalling and Patterning, Genes and Development Division, A STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore. shangwei@imcb.a-star.edu.sg
authors.forename: S-W
authors.initials: SW
authors.lastname: Chong
authors.forename: V
authors.initials: V
authors.lastname: Korzh
authors.forename: Y-J
authors.initials: YJ
authors.lastname: Jiang
mesh_terms: D000818:Animals; D018925:Chemokines / Q000378:metabolism; D004625:Embryo, Nonmammalian / Q000196:embryology; D005346:Fibroblast Growth Factors / Q000378:metabolism; D018398:Homeodomain Proteins / Q000378:metabolism; D035683:MicroRNAs / Q000378:metabolism; D024510:Muscle Development / Q000502:physiology*; D009132:Muscles / Q000196:embryology*; D032446:Myoblasts / Q000166:cytology; D009218:Myosins / Q000378:metabolism; D017510:Protein Folding; D015027:Zebrafish / Q000196:embryology*
chemical_list: D018925:Chemokines; D018398:Homeodomain Proteins; D035683:MicroRNAs; D005346:Fibroblast Growth Factors; D009218:Myosins