Anti-Müllerian hormone serum levels predict response to controlled ovarian hyperstimulation but not embryo quality or pregnancy outcome in oocyte donation.
The objective of this retrospective cross-sectional study was to evaluate the value of basal serum anti-Müllerian hormone (AMH) levels as a predictor of ovarian response and pregnancy outcome in a donor egg program. The study showed that AMH was superior to other biomarkers of ovarian reserve in predicting low and high response in young women selected as oocyte donors, but that it was not predictive of embryo morphology or pregnancy outcome in the recipient population.
Riggs
Ryan
R
Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA.
Kimble
Thomas
T
Oehninger
Sergio
S
Bocca
Silvina
S
Zhao
Yueqin
Y
Leader
Ben
B
Stadtmauer
Laurel
L
D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D001755:Blastocyst; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D018587:Oocyte Donation; D009865:Oocytes / Q000166:cytology; D010062:Ovulation Induction / Q000379:methods*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011256:Pregnancy Outcome; D012372:ROC Curve
D015415:Biomarkers; D054304:Anti-Mullerian Hormone