ICPS: an integrative cancer profiler system.
Founded upon the database of 570 public signatures, ICPS is a web-based application to obtain biomarker profiles among 11 common cancers by integrating genomic alterations with transcription signatures on the basis of a previously developed integrative pipeline. ICPS supports both public data and user's in-house data, and performs meta-analysis at a cancer subtype level by combining heterogeneous datasets. Finally, ICPS returns the robust gene signature containing potential cancer biomarkers that may be useful to carcinogenesis study and clinical cancer diagnosis.


BACKGROUND
http://server.bioicps.org


BACKGROUND
zhxy@mail.tsinghua.edu.cn; zxy-dcs@mail.tsinghua.edu.cn
Zhang
Xin-yu
XY
State Key Laboratory of Intelligent Technology and Systems, Tsinghua National Laboratory for Information Science and Technology, Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China. zhxy@mail.tsinghua.edu.cn
Shi
Lin
L
Liu
Yan
Y
Tian
Feng
F
Zhao
Hai-tao
HT
Miao
Xiao-ping
XP
Huang
Ming-lie
ML
Zhu
Xiao-yan
XY
D015415:Biomarkers / Q000032:analysis; D030541:Databases, Genetic; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D020407:Internet; D015201:Meta-Analysis as Topic; D009369:Neoplasms / Q000235:genetics*; D012984:Software
D015415:Biomarkers