Novel hepatitis E virus genotype in Norway rats, Germany.
Human hepatitis E virus infections may be caused by zoonotic transmission of virus genotypes 3 and 4. To determine whether rodents are a reservoir, we analyzed the complete nucleotide sequence of a hepatitis E-like virus from 2 Norway rats in Germany. The sequence suggests a separate genotype for this hepatotropic virus.
Johne
Reimar
R
Federal Institute for Risk Assessment, Berlin, Germany.
Heckel
Gerald
G
Plenge-Bönig
Anita
A
Kindler
Eveline
E
Maresch
Christina
C
Reetz
Jochen
J
Schielke
Anika
A
Ulrich
Rainer G
RG
D000818:Animals; D000835:Animals, Wild / Q000821:virology; D004197:Disease Reservoirs / Q000821:virology; D005260:Female; D016679:Genome, Viral; D005838:Genotype; D005858:Germany; D016751:Hepatitis E / Q000635:transmission / Q000821:virology; D016752:Hepatitis E virus / Q000235:genetics* / Q000302:isolation & purification* / Q000472:pathogenicity; D006801:Humans; D008099:Liver / Q000821:virology; D008297:Male; D016366:Open Reading Frames; D010802:Phylogeny; D051381:Rats / Q000821:virology*; D015047:Zoonoses / Q000635:transmission / Q000821:virology