Diagnostic value of the rapid influenza antigen test for novel influenza A (H1N1).
We administered both the rapid antigen test and real-time reverse transcriptase polymerase chain reaction (RT-PCR) test to 2154 patients in order to assess the diagnostic value of the rapid antigen test during Korean pandemics of H1N1 2009. The overall sensitivity was 70.0%, specificity was 97.5%, positive predictive value was 97.4%, and negative predictive value was 71.2%. The sensitivity fell and the negative predictive value decreased as the RT-PCR positive rate increased.
Lee
Hyang-Mee
HM
Department of Family Medicine, College of Medicine, Hanyang University, Seoul, South Korea.
Lee
Hang-Mee
HM
Park
Hoon-Ki
HK
Hwang
Hwan-Sik
HS
Chun
Min-Young
MY
Pai
Hyun-Joo
HJ
Oh
Sung Hee
SH
Kim
Duck-An
DA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000956:Antigens, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis*; D007723:Korea; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*; D055815:Young Adult
D000956:Antigens, Viral; D012367:RNA, Viral