Antenatal embolization of a large chorioangioma by percutaneous Glubran 2 injection.
We describe a case of a large chorioangioma diagnosed at 18 weeks' gestation. Because of advanced fetal heart failure at 23 weeks' gestation, embolization of the chorioangioma's vessels was performed by percutaneous injection of Glubran 2 surgical glue. There was no immediate secondary effect of treatment. Devascularization was complete and durable. Signs of fetal cardiac failure normalized after 1 month and a healthy infant was delivered at 38 weeks. To our knowledge this is the first reported case of perinatal survival after successful embolization of a chorioangioma using tissue glue.
Gajewska
K
K
Department of Obstetrics and Gynecology, University Hospital Erasme, Brussels, Belgium.
Herinckx
A
A
Holoye
A
A
D'Haene
N
N
Massez
A
A
Cassart
M
M
Van Rysselberge
M
M
Donner
C
C
D000328:Adult; D003487:Cyanoacrylates / Q000008:administration & dosage*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005315:Fetal Diseases / Q000628:therapy; D005865:Gestational Age; D006333:Heart Failure / Q000628:therapy; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging / Q000628:therapy*; D011256:Pregnancy Outcome; D014014:Tissue Adhesives / Q000008:administration & dosage*; D014463:Ultrasonography
D003487:Cyanoacrylates; D014014:Tissue Adhesives; C421461:glubran 2