title: Correlations between M-CHARTS and PHP findings and subjective perception of metamorphopsia in patients with macular diseases.
abstract: OBJECTIVE
  To assess the correlations between a patient's subjective perception of metamorphopsia and the clinical measurements of metamorphopsia by M-CHARTS and PreView PHP (PHP).
  
  
  METHODS
  The authors designed a 10-item questionnaire focusing on the symptoms of metamorphopsia and verified its validity with a Rasch analysis. M-CHARTS measured the minimum visual angle of a dotted line needed to detect metamorphopsia, and PHP used the hyperacuity function for detection. Subjects were 39 patients with idiopathic epiretinal membrane (ERM), 22 patients with idiopathic macular hole (M-hole), 19 patients with age-related macular degeneration (AMD), and 51 healthy controls.
  
  
  RESULTS
  Rasch analysis suggested the elimination of one question. The nine-item questionnaire score significantly correlated to the M-CHARTS score in ERM (r = 0.59; P = 0.0004) but not in M-hole and to the PHP result in AMD (r = -0.29; P = 0.04) but not in ERM. Eighty percent of ERM patients with greater horizontal M-CHARTS score subjectively perceived horizontal metamorphopsia more often. M-CHARTS showed better sensitivities than PHP in both ERM (89% vs. 42%) and AMD (74% vs. 68%) and better specificity (100% vs. 71%) in healthy controls. Rasch analysis indicated that the present form of the questionnaire is better suited for moderate to severe cases of metamorphopsia than for mild cases.
  
  
  CONCLUSIONS
  The questionnaire appears to be a valid assessment of patient subjective perception of metamorphopsia and can be used to supplement the clinical measurements of metamorphopsia by M-CHARTS and PHP in patients with macular diseases.
authors.affiliation: Department of Ophthalmology, Kinki University Faculty of Medicine, Sakai Hospital, Osaka, Japan.
authors.forename: Eiko
authors.initials: E
authors.lastname: Arimura
authors.forename: Chota
authors.initials: C
authors.lastname: Matsumoto
authors.forename: Hiroki
authors.initials: H
authors.lastname: Nomoto
authors.forename: Shigeki
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Sonoko
authors.initials: S
authors.lastname: Takada
authors.forename: Sachiko
authors.initials: S
authors.lastname: Okuyama
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Shimomura
mesh_terms: D000368:Aged; D019773:Epiretinal Membrane / Q000175:diagnosis; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis*; D012167:Retinal Perforations / Q000175:diagnosis; D012680:Sensitivity and Specificity; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014786:Vision Disorders / Q000175:diagnosis*; D014787:Vision Tests / Q000295:instrumentation*; D014792:Visual Acuity; D014796:Visual Perception