title: Ten years later: a single hospital experience with malignancy in HIV/AIDS.
abstract: OBJECTIVE
  We present our experience in the era of HAART with 5,112 patients having HIV infection or AIDS, treated between 2002 and 2006 in our hospital, 182 of whom had malignancies (3.56%). We compared our findings to those from a similar cohort of patients studied 10 years earlier.
  
  
  METHODS
  The charts were reviewed and data was electronically collected as in our 1993-1998 study. Similar statistical analyses were performed in both studies and the results were compared.
  
  
  RESULTS
  For the current study the average patient age increased by 9 years. A decrease in AIDS-defining cancers (ADC), from 63.6% to 37.3% and a higher incidence of non-AIDS-defining cancers (NADC), 62.7 as opposed to 37.9% was found. No decrease in the incidence of non-Hodgkin's B cell lymphoma (NHL) was noted. There was an increase in the number of opportunistic infections notably hepatitis C virus (HCV) and hepatitis B virus (HBV).
  
  
  CONCLUSIONS
  HIV/AIDS patients on HAART are older, have lower rates of AIDS related Kaposi's sarcoma and a higher incidence of NADCs than did patients in the early HAART era. No decrease in the proportion of NHL was observed.
authors.affiliation: Division of Oncology, Bronx-Lebanon Hospital Center, Bronx, New York 10457, USA. mreed@bronxleb.org
authors.forename: Mary
authors.initials: M
authors.lastname: Reed
authors.forename: John M
authors.initials: JM
authors.lastname: Cosgrove
authors.forename: Richard
authors.initials: R
authors.lastname: Cindrich
authors.forename: Vellore S
authors.initials: VS
authors.lastname: Parithivel
authors.forename: Youhanna
authors.initials: Y
authors.lastname: Gad
authors.forename: Madan
authors.initials: M
authors.lastname: Bangalore
authors.forename: Robert
authors.initials: R
authors.lastname: Uzor
authors.forename: Jawaid
authors.initials: J
authors.lastname: Kalim
authors.forename: Raymundo
authors.initials: R
authors.lastname: Segura
authors.forename: Eugene
authors.initials: E
authors.lastname: Albu
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000401:mortality; D012514:Sarcoma, Kaposi / Q000453:epidemiology