title: New lupane-type triterpenoid saponins from leaves of Oplopanax horridus (Devil's Club).
abstract: Two new lupane type saponins, along with one known saponin were isolated from leaves of Oplopanax horridus (Devil's Club). The structures of the two new compounds were elucidated as 3alpha-hydroxy-lup-20(29)-ene-23, 28-dioic acid-3-O-beta-D-glucopyranoside (2) and 24-nor-3-oxo-lup-20(29)-en-28-oic acid-28-O-alpha-L-rhamnopyranosyl(1''' --> 4")-beta-D-glucopyranosyl(1" --> 6')-beta-D-glucopyranoside (3) on the basis of spectroscopic analysis and chemical evidence. The known compound was identified as 3alpha-hydroxy-lup-20(29)-ene-23, 28-dioic acid (1) by comparison of its spectral data with those reported. Compound 1 was isolated for the first time from the title plant.
authors.affiliation: College of Pharmacy, Liaoning University of Traditional Chinese Medicine, 77 Life one Road, Dalian Economic and Technical Development Zone, Dalian 116600, China.
authors.forename: Pei-Pei
authors.initials: PP
authors.lastname: Liu
authors.forename: Mo
authors.initials: M
authors.lastname: Li
authors.forename: Ting-Guo
authors.initials: TG
authors.lastname: Kang
authors.forename: De-Qiang
authors.initials: DQ
authors.lastname: Dou
authors.forename: David C
authors.initials: DC
authors.lastname: Smith
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028002:Oplopanax / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*; D053978:Pentacyclic Triterpenes
chemical_list: D014315:Triterpenes; C480546:lupane; D053978:Pentacyclic Triterpenes