Copper-catalyzed olefin aminoacetoxylation.
A new catalyst system for intramolecular olefin aminoacetoxylation is described. In contrast to previously reported palladium- and copper-catalyzed systems, the conditions outlined in this communication favor piperdine formation with terminal olefin substrates and induce cyclization with traditionally less reactive disubstituted olefins.
Mancheno
Danny E
DE
Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
Thornton
Aaron R
AR
Stoll
Armin H
AH
Kong
Aidi
A
Blakey
Simon B
SB
D000096:Acetone / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000475:Alkenes; D000588:Amines; D000096:Acetone; D003300:Copper