Dnmt3a: addiction's molecular forget-me-not?
A new study examines the contribution of DNA methylation to long-term behavioral and morphological changes produced by cocaine exposure or chronic social defeat stress.
Hopf
F Woodward
FW
Bonci
Antonello
A
D000818:Animals; D002908:Chronic Disease; D019970:Cocaine-Related Disorders / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology*; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000235:genetics* / Q000378:metabolism*; D019175:DNA Methylation; D000090205:DNA Methyltransferase 3A; D049229:Dendritic Spines / Q000187:drug effects / Q000473:pathology / Q000502:physiology; D004291:Dominance-Subordination; D051379:Mice; D008959:Models, Neurological; D009714:Nucleus Accumbens / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D013315:Stress, Psychological / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology*
C000715535:Dnmt3a protein, mouse; D004248:DNA (Cytosine-5-)-Methyltransferases; D000090205:DNA Methyltransferase 3A