title: Paraneoplastic Necrotizing Myopathy with a Mild Inflammatory Component: A Case Report and Review of the Literature.
abstract: Inflammatory myopathies such as dermatomyositis and polymyositis are well-recognized paraneoplastic syndromes. Little is known, however, about necrotizing myopathies in association with cancer. We here describe a case of paraneoplastic necrotizing myopathy with a mild inflammatory infiltrate in a patient with adenocarcinoma. After the rapid development of a severe, disabling muscle weakness, the patient experienced near complete recovery within 4 months under oral prednisone treatment. In the context of the presented case, we will review current knowledge about paraneoplastic necrotizing myopathies.
authors.affiliation: Department of Neurology, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Susanne
authors.initials: S
authors.lastname: Wegener
authors.forename: Juliane
authors.initials: J
authors.lastname: Bremer
authors.forename: Paul
authors.initials: P
authors.lastname: Komminoth
authors.forename: Hans H
authors.initials: HH
authors.lastname: Jung
authors.forename: Michael
authors.initials: M
authors.lastname: Weller