title: High-performance, flexible enzymatic glucose biosensor based on ZnO nanowires supported on a gold-coated polyester substrate.
abstract: The present work demonstrates the fabrication and performance of an enzymatic glucose biosensor based on ZnO nanowires (NWs) deposited on a Au-coated polyester (PET) substrate. Electrodeposition of ZnO NWs on the conducting PET substrate was carried out at 70 degrees C in an aqueous electrolyte consisting of zinc nitrate mixed with potassium chloride. Glucose oxidase (GOx) was subsequently immobilized on the as-synthesized ZnO NWs, and the electrocatalytic properties of GOx-immobilized ZnO NWs were evaluated by amperometry. The resulting GOx/ZnO-NWs/Au/PET bioelectrode exhibits excellent electrocatalytic performance with a high sensitivity of 19.5 muA mM(-1) cm(-2), a low Michaelis-Menten constant of 1.57 mM, and a fast response time of <5 s for the amperometric detection of glucose. The present study illustrates the feasibility of realizing light-weight, flexible, high-performance sensing devices using ZnO NWs.
authors.affiliation: WATLab and Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
authors.forename: Debabrata
authors.initials: D
authors.lastname: Pradhan
authors.forename: Farnaz
authors.initials: F
authors.lastname: Niroui
authors.forename: K T
authors.initials: KT
authors.lastname: Leung
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry; D005947:Glucose / Q000032:analysis / Q000737:chemistry*; D006046:Gold; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology / Q000379:methods*; D053770:Nanowires; D011091:Polyesters; D013379:Substrate Specificity; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D011091:Polyesters; D006046:Gold; D005947:Glucose; D015034:Zinc Oxide