title: Subacute axonal neuropathy in Parkinson's disease with cobalamin and vitamin B6 deficiency under duodopa therapy.
abstract: We describe two patients who developed subacute axonal peripheral neuropathy under duodopa treatment. Comprehensive diagnostic workup including muscle and sural nerve biopsy revealed that the most probable cause of subacute axonal peripheral neuropathy was cobalamin and vitamin B6 deficiency in both the patients.
authors.affiliation: Department of Neurology, Asklepios Klinik Barmbek, Hamburg, Germany. p.urban@asklepios.com
authors.forename: Peter P
authors.initials: PP
authors.lastname: Urban
authors.forename: Ingmar
authors.initials: I
authors.lastname: Wellach
authors.forename: Siegbert
authors.initials: S
authors.lastname: Faiss
authors.forename: Peter
authors.initials: P
authors.lastname: Layer
authors.forename: Thorsten
authors.initials: T
authors.lastname: Rosenkranz
authors.forename: Karl
authors.initials: K
authors.lastname: Knop
authors.forename: Joachim
authors.initials: J
authors.lastname: Weis
mesh_terms: D000368:Aged; D000978:Antiparkinson Agents / Q000009:adverse effects; D004295:Dihydroxyphenylalanine / Q000008:administration & dosage / Q000009:adverse effects; D004333:Drug Administration Routes; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy* / Q000209:etiology; D014805:Vitamin B 12 / Q000627:therapeutic use*; D026681:Vitamin B 6 Deficiency / Q000139:chemically induced / Q000188:drug therapy*; D014803:Vitamin B Complex / Q000627:therapeutic use*
chemical_list: D000978:Antiparkinson Agents; D014803:Vitamin B Complex; D004295:Dihydroxyphenylalanine; D014805:Vitamin B 12