Successful eradication of a monoclonal strain of Klebsiella pneumoniae during a K. pneumoniae carbapenemase-producing K. pneumoniae outbreak in a surgical intensive care unit in Miami, Florida.
We describe the investigation and control of a Klebsiella pneumoniae carbapenemase-producing K. pneumoniae outbreak in a 20-bed surgical intensive care unit during the period from January 1, 2009 through January 1, 2010. Nine patients were either colonized or infected with a monoclonal strain of K. pneumoniae. The implementation of a bundle of interventions on July 2009 successfully controlled the further horizontal spread of this organism.
Munoz-Price
L Silvia
LS
Division of Infectious Diseases, Department of Medicine, University of Miami, and Jackson Memorial Hospital, Miami, FL, USA. smunozprice@med.miami.edu
De La Cuesta
Carolina
C
Adams
Stephen
S
Wyckoff
Mary
M
Cleary
Timothy
T
McCurdy
Sandra P
SP
Huband
Michael D
MD
Lemmon
M Megan
MM
Lescoe
Marykay
M
Dibhajj
Fadia B
FB
Hayden
Mary K
MK
Lolans
Karen
K
Quinn
John P
JP
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D003422:Critical Care; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D005431:Florida / Q000453:epidemiology; D006784:Hospitals, Teaching; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007710:Klebsiella Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016896:Treatment Outcome; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C495220:beta-lactamase KPC-3, Klebsiella pneumoniae