Complication of corticosteroid treatment by acute Plasmodium malariae infection confirmed by small-subunit rRNA sequencing.
We report a case of acute Plasmodium malariae infection complicating corticosteroid treatment for membranoproliferative glomerulonephritis in a patient from an area where P. malariae infection is not endemic. A peripheral blood smear showed typical band-form trophozoites compatible with P. malariae or Plasmodium knowlesi. SSU rRNA sequencing confirmed the identity to be P. malariae.
To
Kelvin K W
KK
Carol Yu Centre for Infection, Department of Microbiology, The University of Hong Kong, Hong Kong.
Teng
Jade L L
JL
Wong
Samson S Y
SS
Ngan
Antonio H Y
AH
Yuen
Kwok-Yung
KY
Woo
Patrick C Y
PC
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D001769:Blood / Q000469:parasitology; D016054:DNA, Protozoan / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D020459:Genes, rRNA; D015432:Glomerulonephritis, Membranoproliferative / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D008288:Malaria / Q000175:diagnosis* / Q000469:parasitology; D008297:Male; D008853:Microscopy; D008969:Molecular Sequence Data; D010965:Plasmodium malariae / Q000235:genetics / Q000302:isolation & purification*; D016053:RNA, Protozoan / Q000235:genetics; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D017422:Sequence Analysis, DNA
D000305:Adrenal Cortex Hormones; D016054:DNA, Protozoan; D004275:DNA, Ribosomal; D016053:RNA, Protozoan; D012337:RNA, Ribosomal, 18S