title: Chemotherapy-related visual system toxicity.
abstract: Most, if not all, of the studies that report cognitive impairments in patients who have been treated with cancer chemotherapy also report deficits involving the visual system (e.g., visual-spatial function or visual memory). The visual system seems like a likely susceptible target of cytotoxic drugs. Therefore, some portion of the vision-related cognitive deficits ofchemo fog/chemo brain might result from a direct action of the drugs or from site/site interaction between effects on the visual system and other critical brain regions. This chapter is a succint summary of a more expanded review.
authors.affiliation: Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, USA. robert.raffa@temple.edu
authors.forename: Robert B
authors.initials: RB
authors.lastname: Raffa
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003072:Cognition Disorders / Q000139:chemically induced / Q000503:physiopathology; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D014785:Vision, Ocular / Q000187:drug effects*
chemical_list: D000970:Antineoplastic Agents