title: Persistence of human bocavirus DNA in immunocompromised children.
abstract: Human bocavirus is frequently detected in immunocompetent as well as in immunocompromised children. However, the course of infection in immunocompromised children is still poorly investigated. In the present study, we describe 4 cases of repeat human bocavirus detection in the presence of severe immunodeficiency. In the view of homologous viral sequences identified in serial samples, possible persistence and reactivation in these patients are discussed.
authors.affiliation: Department of Virology, Freiburg University Medical Center, Freiburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Schenk
authors.forename: Barbara
authors.initials: B
authors.lastname: Maier
authors.forename: Markus
authors.initials: M
authors.lastname: Hufnagel
authors.forename: Brigitte
authors.initials: B
authors.lastname: Strahm
authors.forename: Udo
authors.initials: U
authors.lastname: Kontny
authors.forename: Dieter
authors.initials: D
authors.lastname: Neumann-Haefelin
authors.forename: Valeria
authors.initials: V
authors.lastname: Falcone
mesh_terms: D000293:Adolescent; D002675:Child, Preschool; D004279:DNA, Viral / Q000378:metabolism*; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D056661:Human bocavirus / Q000235:genetics*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008297:Male; D009305:Nasopharynx / Q000821:virology; D010322:Parvoviridae Infections / Q000276:immunology / Q000821:virology*; D016133:Polymerase Chain Reaction; D019562:Viral Load
chemical_list: D004279:DNA, Viral