Sclerotherapy of lymphangiomas of the head and neck.
Lymphangiomas are congenital malformations of the lymphatic system that consist of cysts of varying size. Although they are benign, they can undergo progressive growth with compression and infiltration of adjacent structures. Surgical excision has been the cornerstone of treatment, although total excision of the lymphangioma can be a major challenge and may be associated with severe complications. Therefore, a variety of nonsurgical methods have been proposed to reduce the surgical morbidity and to decrease the recurrence rate. Percutaneous sclerotherapy of lymphangioma involves the injection of sclerosing substances into the lymphangioma cysts. During the past years, different sclerosants and sclerosant techniques have been developed. This review summarizes the current knowledge on sclerotherapy of lymphangiomas of the head and neck.
Wiegand
Susanne
S
Department of Otolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Campus Marburg, Marburg, Germany. swiegand@med.uni-marburg.de
Eivazi
Behfar
B
Zimmermann
Annette P
AP
Sesterhenn
Andreas M
AM
Werner
Jochen A
JA
D001761:Bleomycin / Q000627:therapeutic use; D003973:Diatrizoate / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D004338:Drug Combinations; D000431:Ethanol / Q000627:therapeutic use; D005227:Fatty Acids / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D010844:Picibanil / Q000627:therapeutic use; D011409:Propylene Glycols / Q000627:therapeutic use; D018570:Risk Assessment; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome; D015028:Zein / Q000627:therapeutic use
D004338:Drug Combinations; D005227:Fatty Acids; D011409:Propylene Glycols; D012597:Sclerosing Solutions; D001761:Bleomycin; D003973:Diatrizoate; D010844:Picibanil; D000431:Ethanol; D015028:Zein; C020481:alcoholic prolamine solution; D004318:Doxycycline