Clinical profile of ocular sarcoidosis in a South Indian patient population.
OBJECTIVE
To report the ocular and systemic features in patients with definite and presumed sarcoidosis presenting to a tertiary referral eye center in south India.


METHODS
Retrospective observational case series. Records of 51 patients with diagnosis of sarcoidosis were retrieved. A complete ophthalmic evaluation and systemic examination by a pulmonologist with appropriate laboratory investigations were done in all patients. Results were statistically analyzed using SPSS software.


RESULTS
The mean age group was 45.14 ± 10.91 years. Females were more common and 31 cases were biopsy proven. Panuveitis and thoracic involvement was the most common ophthalmic and systemic manifestations of sarcoid respectively. Posterior synechiae, granulomatous keratic precipitates, increased anterior chamber reaction, and cystoid macular edema were significantly more common in those presenting initially to an ophthalmologist.


CONCLUSIONS
Sarcoidosis is increasingly recognized in south India as well. A complete review of systems with appropriate investigations is essential to prevent ocular or systemic morbidity.
Babu
Kalpana
K
Vittala International Institute of Ophthalmology & Prabha Eye Clinic and Research Center, Bangalore, India. kb_7375@yahoo.co.in
Kini
Raghuvir
R
Mehta
Ravindra
R
Abraham
Mariamma Philips
MP
Subbakrishna
D K
DK
Murthy
Krishna R
KR
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data*; D005128:Eye Diseases / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D015864:Panuveitis / Q000209:etiology; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology*; D017678:Sex Distribution; D013256:Steroids / Q000008:administration & dosage; D013896:Thoracic Diseases / Q000209:etiology; D055815:Young Adult
D013256:Steroids; D008727:Methotrexate