[Sexual and reproductive function in males with somatotropinoma].
The examination of 72 males with somatotropinoma has found that 65% of such patients have hypogonadism which is essential in pathogenesis of sexual dysfunction and spermatogenetic disorders. However, hypogonadism in males with somatotropinoma does not provoke sexual dysfunction in most the cases. High production of somatotropic hormone and insulin-like growth factor 1 in somatotropinoma leads to prostatic hyperplasia which is not accompanied with a rise of a PSA level and symptoms of infravesical obstruction.
Rozhivanov
R V
RV
Molitvoslovova
N N
NN
Rozhinskaia
L Ia
LIa
Kurbatov
D G
DG
D000236:Adenoma / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D000328:Adult; D013006:Growth Hormone / Q000097:blood; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D012735:Sexual Dysfunction, Physiological / Q000097:blood / Q000209:etiology / Q000503:physiopathology*
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone