Performance evaluation and application of molecularly imprinted polymer for separation of carbamazepine in aqueous solution.
A molecularly imprinted polymer (MIP) for selective adsorption of carbamazepine (CBZ) in aqueous solution was synthesized by precipitation polymerization using CBZ as a template molecule and methacrylic acid (MAA) as a functional monomer. The performance of the CBZ-MIP was evaluated in terms of selectivity, adsorption capacity, binding characteristics, loading volume, and elution volume. The CBZ-MIP exhibited a high affinity for CBZ over the competitive compound (Diclofenac) and was more suitable to remove low concentrations of CBZ in large-volume water samples. A binding performance experiment indicated that the adsorption of CBZ-MIP was characterized by both specific and non-specific binding interactions. Moreover, the regenerability of the MIP was affirmed in ten sequential cycles of adsorption/desorption without a significant loss in recovery. Finally, the CBZ-MIP was applied to enrich CBZ in environmental water samples, and the CBZ concentrations were subsequently determined using HPLC-UV. The results were in good agreement with corresponding LC-MS/MS data.
Dai
Chao-Meng
CM
State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Shanghai, 200092, China; Department of Environmental Technology, Chair of Environmental Process Engineering, Technical University of Berlin, Berlin, Germany.
Geissen
Sven-Uwe
SU
Department of Environmental Technology, Chair of Environmental Process Engineering, Technical University of Berlin, Berlin, Germany. Electronic address: sven.geissen@tu-berlin.de.
Zhang
Ya-Lei
YL
State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Shanghai, 200092, China. Electronic address: zhangyalei@tongji.edu.cn.
Zhang
Yong-Jun
YJ
Department of Environmental Technology, Chair of Environmental Process Engineering, Technical University of Berlin, Berlin, Germany.
Zhou
Xue-Fei
XF
State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Shanghai, 200092, China.
D000327:Adsorption; D000927:Anticonvulsants / Q000302:isolation & purification*; D002220:Carbamazepine / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D057230:Limit of Detection; D011108:Polymers / Q000737:chemistry*; D012996:Solutions; D014874:Water Pollutants, Chemical / Q000302:isolation & purification*
D000927:Anticonvulsants; D011108:Polymers; D012996:Solutions; D014874:Water Pollutants, Chemical; D002220:Carbamazepine