title: A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning.
abstract: The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators.
authors.affiliation: Hokkaido University School of Medicine, Kita-ku Kita 12 Jo Nishi 5 Chome, Sapporo, Japan. kensuth@med.hokudai.ac.jp
authors.forename: Kenneth
authors.initials: K
authors.lastname: Sutherland
authors.forename: Satoshi
authors.initials: S
authors.lastname: Miyajima
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Date
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shirato
authors.forename: Masayori
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Masao
authors.initials: M
authors.lastname: Murakami
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Yamagiwa
authors.forename: Paul
authors.initials: P
authors.lastname: Bolton
authors.forename: Toshiki
authors.initials: T
authors.lastname: Tajima
mesh_terms: D005134:Eye Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D007834:Lasers; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D009010:Monte Carlo Method; D058958:Organs at Risk / Q000528:radiation effects; D061766:Proton Therapy; D011829:Radiation Dosage; D011879:Radiotherapy Dosage; D047368:Tumor Burden; D011522:Protons
chemical_list: D011522:Protons
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