title: The language of histone crosstalk.
abstract: It has been suggested that a specific pattern of histone posttranslational modifications and their crosstalk may constitute a code that determines transcriptional outcomes. However, recent studies indicate that histone modifications have context-dependent effects, making their interplay more like a language within the chromatin signaling pathway than a code.
authors.affiliation: Stowers Institute for Medical Research, Kansas City, MO 64110, USA.
authors.forename: Jung-Shin
authors.initials: JS
authors.lastname: Lee
authors.forename: Edwin
authors.initials: E
authors.lastname: Smith
authors.forename: Ali
authors.initials: A
authors.lastname: Shilatifard
mesh_terms: D002843:Chromatin / Q000378:metabolism*; D042421:Histone Code; D006657:Histones / Q000378:metabolism*; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D006657:Histones
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