Magnetic resonance cholangiography with mangafodipir trisodium in Caroli's disease with pancreas involvement.
BACKGROUND
Caroli's disease is a rare congenital disorder first described by Caroli in 1958. This abnormality consists of non-obstructive, saccular or fusiform dilation of the intrahepatic bile ducts resulting in cystic lesions; similar abnormalities may also occur in the kidneys and pancreas.


METHODS
We illustrate the role of enhanced mangafodipir trisodium magnetic resonance imaging in a patient with sporadic non-hereditary Caroli's disease associated with pancreatic involvement in which mangafodipir trisodium magnetic resonance imaging characterized part of the cystic liver lesions as saccular dilations of the intrahepatic bile ducts of the left lobe, allowing diagnosis of the disease.


CONCLUSIONS
We strongly recommend hepatobiliary magnetic resonance imaging with mangafodipir trisodium in such patients.
Maurea
Simone
S
Department of Biomorphological and Functional Sciences (DSBMF), University Federico II of Napoli (UNINA), Biostructures and Bioimmages Institution (IBB), National Research Council (CNR), Naples, Italy. maurea@unina.it
Mollica
Carmine
C
Imbriaco
Massimo
M
Fusari
Mario
M
Camera
Luigi
L
Salvatore
Marco
M
D000328:Adult; D016767:Caroli Disease / Q000150:complications / Q000000981:diagnostic imaging*; D002758:Cholangiography / Q000379:methods*; D003287:Contrast Media; D004492:Edetic Acid / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D011732:Pyridoxal Phosphate / Q000031:analogs & derivatives*
D003287:Contrast Media; D011732:Pyridoxal Phosphate; D004492:Edetic Acid; C060076:N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid