title: [Tigecycline--a new antibiotic].
abstract: Tigecycline belongs to a new class of antimicrobial agents, the glycylcyclines, which are structurally derived from tetracyclines. It is effective against both gram positive and gram negative bacteria, aerobes and anaerobes and bacteria that have developed resistance against the classic tetracyclines. Although there is an increased risk for serious adverse events, tigecycline is important for treatment of patients with complicated infections of moderate severity where other antimicrobials cannot be used.
authors.affiliation: Statens legemiddelverk, Sven Oftedalsvei 8, 0950 Oslo, Norway. venke.skibeli@legemiddelverket.no
authors.forename: Venke
authors.initials: V
authors.lastname: Skibeli
authors.forename: Ingvild
authors.initials: I
authors.lastname: Aaløkken
authors.forename: Egil
authors.initials: E
authors.lastname: Lingaas
authors.forename: Tore
authors.initials: T
authors.lastname: Midtvedt
authors.forename: Claus Ola
authors.initials: CO
authors.lastname: Solberg
authors.forename: Kjetil K
authors.initials: KK
authors.lastname: Melby
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D024881:Drug Resistance, Bacterial; D006801:Humans; D008911:Minocycline / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000737:chemistry / Q000627:therapeutic use; D000078304:Tigecycline
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline