Mitosis and cell death in the optic lobes of workers, queens and drones of the honey bee (Apis mellifera) during metamorphosis.
Colonies of the honey bee, Apis mellifera, consist of males and two female castes: workers and queens. The castes and males from A. mellifera have a distinct morphology, physiology and behaviour that correlate with their roles in the society and are characterized by some brain polymorphisms. Compound eyes are one of the characteristics that differ among the castes and sexes. A. mellifera is a holometabolous insect; therefore, the development of adult organs during metamorphosis, which will produce these differences, requires the precise coordination of three main programmed cellular processes: proliferation, differentiation and death. These processes take place simultaneously during pupation. Our purpose was to investigate cell division and death in the optic lobes (OL) of workers, queens and males during pupation to identify how the differences in the compound eyes in adults of these classes are achieved. The results showed that OL differentiation follows a similar pattern in the three classes of individuals studied, without structural differences in their development. The main non-structural differences involve cell division, mortality rates and timing. The results suggest a modelling of the brain during differentiation, which contributes to the specific functions of each individual class.
Roat
Thaisa Cristina
TC
Departmento de Biologia, Instituto de Biociencias - Universidade Estadual Paulista Julio de Mesquita Filho, Av. 24A, no. 1515, Bela Vista, 13506-900 Rio Claro, SP, Brazil. thaisaroat@yahoo.com.br
Landim
Carminda da Cruz
Cda C
D000818:Animals; D001516:Bees / Q000254:growth & development*; D016923:Cell Death; D054910:Compound Eye, Arthropod / Q000254:growth & development; D005260:Female; D008297:Male; D008675:Metamorphosis, Biological; D008938:Mitosis; D009899:Optic Lobe, Nonmammalian / Q000166:cytology / Q000254:growth & development*
Neurosci Lett. 1995 Sep 8;197(2):145-8
8552281
Dev Biol. 1992 Jan;149(1):134-48
1728583
J Comp Neurol. 1996 Mar 25;367(1):10-20
8867280
Wilhelm Roux Arch Entwickl Mech Org. 1970 Sep;164(3):247-260
28304969
J Comp Neurol. 2000 Feb 14;417(3):349-65
10683609
Eur J Biochem. 1978 Mar;84(1):1-15
206429
J Biol Chem. 1982 Jun 10;257(11):6064-72
6281254
J Comp Neurol. 1999 Nov 8;414(1):97-113
10494081
Chromosoma. 1997 Nov;106(6):348-60
9362543
Learn Mem. 1998 May-Jun;5(1-2):90-101
10454374
Dev Biol. 1976 Oct 15;53(2):217-40
825400
J Neurobiol. 2003 Oct;57(1):1-14
12973824
Development. 1998 Jan;125(2):269-77
9486800
Dev Biol. 1988 Jan;125(1):145-57
3119399