title: The role of surface functionality on acute cytotoxicity, ROS generation and DNA damage by cationic gold nanoparticles.
authors.affiliation: Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Apiwat
authors.initials: A
authors.lastname: Chompoosor
authors.forename: Krishnendu
authors.initials: K
authors.lastname: Saha
authors.forename: Partha S
authors.initials: PS
authors.lastname: Ghosh
authors.forename: Dylan J
authors.initials: DJ
authors.lastname: Macarthy
authors.forename: Oscar R
authors.initials: OR
authors.lastname: Miranda
authors.forename: Zheng-Jiang
authors.initials: ZJ
authors.lastname: Zhu
authors.forename: Kathleen F
authors.initials: KF
authors.lastname: Arcaro
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Rotello
mesh_terms: D002412:Cations / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D020552:Comet Assay; D004249:DNA Damage / Q000187:drug effects*; D006046:Gold / Q000737:chemistry* / Q000633:toxicity*; D006367:HeLa Cells; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity*; D008962:Models, Theoretical; D009369:Neoplasms / Q000188:drug therapy; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D002412:Cations; D017382:Reactive Oxygen Species; D006046:Gold
references.citation: Chem Rev. 2005 Apr;105(4):1547-62
references.pmid: 15826019
references.citation: Acc Chem Res. 2000 Jan;33(1):27-36
references.pmid: 10639073
references.citation: J Am Chem Soc. 2010 Feb 10;132(5):1517-9
references.pmid: 20085324
references.citation: Biologicals. 1998 Mar;26(1):49-59
references.pmid: 9637749
references.citation: Curr Mol Med. 2006 Sep;6(6):651-63
references.pmid: 17022735
references.citation: J Appl Toxicol. 2010 Apr;30(3):212-7
references.pmid: 19902477
references.citation: J Am Chem Soc. 2008 Oct 29;130(43):14139-43
references.pmid: 18826222
references.citation: Toxicol Lett. 2010 Feb 1;192(2):108-14
references.pmid: 19853026
references.citation: Small. 2006 Jun;2(6):766-73
references.pmid: 17193121
references.citation: ACS Nano. 2009 Jul 28;3(7):1620-7
references.pmid: 21452863
references.citation: Small. 2009 Aug 17;5(16):1897-910
references.pmid: 19437466
references.citation: ACS Nano. 2008 Aug;2(8):1639-44
references.pmid: 19206367
references.citation: J Am Chem Soc. 2010 Mar 3;132(8):2642-5
references.pmid: 20131834
references.citation: Environ Mol Mutagen. 2000;35(3):206-21
references.pmid: 10737956
references.citation: J Am Chem Soc. 2009 Aug 19;131(32):11353-60
references.pmid: 19624128
references.citation: J Am Chem Soc. 2009 Apr 29;131(16):5728-9
references.pmid: 19351115
references.citation: Small. 2010 Jan;6(1):12-21
references.pmid: 19844908
references.citation: J Am Chem Soc. 2003 Jul 2;125(26):7790-1
references.pmid: 12822983
references.citation: Biochim Biophys Acta. 2008 Oct;1778(10):2405-12
references.pmid: 18722340
references.citation: Science. 2006 Feb 3;311(5761):622-7
references.pmid: 16456071
references.citation: Small. 2009 Jul;5(13):1553-61
references.pmid: 19326357
references.citation: Small. 2009 Sep;5(18):2067-76
references.pmid: 19642089
references.citation: Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9138-43
references.pmid: 12886020
references.citation: EMBO J. 2007 Apr 4;26(7):1749-60
references.pmid: 17347651
references.citation: Chem Rev. 1999 Sep 8;99(9):2467-98
references.pmid: 11749487
references.citation: Small. 2008 Jan;4(1):153-9
references.pmid: 18081130
references.citation: Langmuir. 2005 Nov 8;21(23):10644-54
references.pmid: 16262332
references.citation: Small. 2007 Nov;3(11):1941-9
references.pmid: 17963284
references.citation: Small. 2005 Mar;1(3):325-7
references.pmid: 17193451
references.citation: Cell Death Differ. 2005 Nov;12 Suppl 2:1528-34
references.pmid: 16247500
references.citation: Cell Death Differ. 2008 Jan;15(1):171-82
references.pmid: 17917680
references.citation: Toxicol Appl Pharmacol. 2009 Apr 1;236(1):16-24
references.pmid: 19162059
references.citation: Bioconjug Chem. 2004 Jul-Aug;15(4):897-900
references.pmid: 15264879
references.citation: ACS Nano. 2008 Nov 25;2(11):2213-8
references.pmid: 19206385
references.citation: Mol Pharm. 2009 May-Jun;6(3):951-8
references.pmid: 19341312
references.citation: Nat Mater. 2009 Jul;8(7):543-57
references.pmid: 19525947