title: Assessment of global function of left ventricle with dual-source CT in patients with severe arrhythmia: a comparison with the use of two-dimensional transthoracic echocardiography.
abstract: To evaluate the agreement between dual-source computed tomography (DSCT) and two-dimensional transthoracic echocardiography (2D-TTE) with respect to the assessment of global left ventricular (LV) function in patients with severe arrhythmia. With 2D-TTE serving as the reference method, we performed both DSCT and 2D-TTE, at an interval of less than 2 days, in 54 patients with severe arrhythmia (average heart rate difference >30 beats per min) before open heart surgery for evaluation of valvular heart disease (VHD) and coronary artery disease. DSCT was performed using retrospective electrocardiography (ECG) without dose modulation. Ten phases of the cardiac cycle were analyzed for identification of end-diastolic and end-systolic phases with ECG-editing. Pearson's correlation coefficient (r) and Bland-Altman analysis were used to determine agreement for parameters of LV global function. Correlation between DSCT and 2D-TTE measurements was good or excellent in terms of the values of the LV ejection fraction (51.0 ± 11.4% vs. 55.8 ± 11.6%; r = 0.8), LV end-diastolic volume (179.5 ± 98.6 ml vs. 152.1 ± 73.8 ml; r = 0.95), LV end-systolic volume (90.7 ± 60.7 ml vs. 69.1 ± 46.8 ml; r = 0.90), and LV stroke volume (89.0 ± 48.1 ml vs. 82.9 ± 37.3 ml; r = 0.89). Left ventricular ejection fraction measured using DSCT was less than that measured using 2D-TTE by an average of -4.8 ± 7.3%. Dual-source CT with ECG editing can provide results comparable to those of 2D-TTE for assessment of LV global function in patients with severe arrhythmia.
authors.affiliation: Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea.
authors.forename: Song Soo
authors.initials: SS
authors.lastname: Kim
authors.forename: Sung Min
authors.initials: SM
authors.lastname: Ko
authors.forename: Meong Gun
authors.initials: MG
authors.lastname: Song
authors.forename: Joon Suk
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D056910:Republic of Korea; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013318:Stroke Volume; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left
references.citation: Br J Radiol. 2010 Jan;83(985):28-34
references.pmid: 19546180
references.citation: Int J Cardiol. 2008 Aug 1;128(1):69-76
references.pmid: 17692410
references.citation: AJR Am J Roentgenol. 2007 Sep;189(3):567-73
references.pmid: 17715102
references.citation: J Comput Assist Tomogr. 2006 Jul-Aug;30(4):555-63
references.pmid: 16845283
references.citation: Eur Radiol. 2006 Feb;16(2):342-57
references.pmid: 16132917
references.citation: Int J Cardiovasc Imaging. 2008 Mar;24(3):317-25
references.pmid: 17701445
references.citation: J Am Soc Echocardiogr. 2004 Oct;17(10):1086-119
references.pmid: 15452478
references.citation: Eur Radiol. 2005 Feb;15 Suppl 2:B23-32
references.pmid: 15801054
references.citation: Radiology. 2008 Oct;249(1):71-80
references.pmid: 18796669
references.citation: Eur Radiol. 2006 Jul;16(7):1409-15
references.pmid: 16770652
references.citation: J Am Soc Echocardiogr. 1989 Sep-Oct;2(5):358-67
references.pmid: 2698218
references.citation: J Cardiogr. 1985 Jun;15(2):273-84
references.pmid: 3937859
references.citation: Invest Radiol. 2006 May;41(5):429-35
references.pmid: 16625105
references.citation: Circulation. 1987 Jul;76(1):44-51
references.pmid: 3594774
references.citation: Eur Radiol. 2005 Jan;15(1):111-7
references.pmid: 15565319
references.citation: J Am Coll Cardiol. 1995 Nov 15;26(6):1516-21
references.pmid: 7594079
references.citation: Circulation. 1979 Oct;60(4):760-6
references.pmid: 476879
references.citation: Radiology. 2008 May;247(2):346-55
references.pmid: 18372455
references.citation: Circulation. 1979 Sep;60(3):547-55
references.pmid: 455617
references.citation: Am J Cardiol. 1999 Apr 1;83(7):1022-6
references.pmid: 10190513
references.citation: Circulation. 2006 Aug 15;114(7):e257-354
references.pmid: 16908781
references.citation: Eur Radiol. 2007 Apr;17(4):994-1008
references.pmid: 17066290
references.citation: J Nucl Cardiol. 2006 Jul;13(4):480-7
references.pmid: 16919571
references.citation: J Am Coll Cardiol. 2006 Nov 21;48(10):2034-44
references.pmid: 17112993
references.citation: Eur Heart J. 2008 Jan;29(2):191-7
references.pmid: 18089704
references.citation: Cardiology. 2008;109(2):135-42
references.pmid: 17713329
references.citation: Radiologe. 2007 Apr;47(4):287-90, 292-4
references.pmid: 17285272
references.citation: Acta Radiol. 2003 Nov;44(6):604-11
references.pmid: 14616204
references.citation: AJR Am J Roentgenol. 2008 Aug;191(2):448-54
references.pmid: 18647916
references.citation: J Nucl Med. 2006 Aug;47(8):1288-94
references.pmid: 16883007
references.citation: Am J Cardiol. 2005 Mar 15;95(6):809-13
references.pmid: 15757621
references.citation: AJR Am J Roentgenol. 2008 Jun;190(6):1583-90
references.pmid: 18492910
references.citation: JACC Cardiovasc Imaging. 2008 Jan;1(1):94-106
references.pmid: 19356412
references.citation: J Am Coll Cardiol. 1992 Aug;20(2):301-6
references.pmid: 1634664
references.citation: Eur J Radiol. 2009 Sep;71(3):480-5
references.pmid: 18650043
references.citation: Radiology. 2009 Dec;253(3):672-80
references.pmid: 19864512
references.citation: Invest Radiol. 2007 Jul;42(7):491-8
references.pmid: 17568271
references.citation: Int J Cardiovasc Imaging. 2010 Feb;26 Suppl 1:93-101
references.pmid: 20033490
references.citation: Eur J Echocardiogr. 2006 Aug;7(4):308-14
references.pmid: 16098814
references.citation: Eur Heart J. 2000 Aug;21(16):1387-96
references.pmid: 10952828