Giardiasis and poor vitamin A status among aboriginal school children in rural Malaysia.
A cross-sectional study was carried out on 241 primary schoolchildren in Pahang, Malaysia to update their vitamin A status and to investigate the association of poor vitamin A status with their health and socioeconomic factors. All children were screened for intestinal parasitic infections. Blood samples were collected and vitamin A status was assessed. Socioeconomic data were collected by using pre-tested questionnaires. The results showed that 66 (27.4%) children had low serum retinol levels (< 0.70 micromol/L). Giardiasis and severe ascariasis were significantly associated with low serum retinol levels (P = 0.004 and P = 0.018, respectively). Logistic regression confirmed the significant association of giardiasis with low serum retinol (odds ratio = 2.7, 95% confidence interval = 1.3-5.5). In conclusion, vitamin A deficiency is still a public health problem in rural Malaysia. Vitamin A supplementation and treatment of intestinal parasitic infections should be distributed periodically to these children to improve their health and nutritional status.
Al-Mekhlafi
Hesham M
HM
Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. halmekhlafi@yahoo.com
Surin
Johari
J
Sallam
Atiya A
AA
Abdullah
Ariffin W
AW
Mahdy
Mohammed A K
MA
D002648:Child; D005260:Female; D005873:Giardiasis / Q000453:epidemiology*; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D012424:Rural Population; D011795:Surveys and Questionnaires; D014801:Vitamin A / Q000097:blood; D014802:Vitamin A Deficiency / Q000453:epidemiology*
D014801:Vitamin A
Lancet. 2003 Dec 20;362(9401):2052-8
14697804
Cent Afr J Med. 1999 Jan;45(1):14-9
10444891
Southeast Asian J Trop Med Public Health. 2007 Nov;38(6):998-1007
18613540
Br J Nutr. 1993 May;69(3):817-25
8329356
Int J Vitam Nutr Res. 1997;67(2):71-90
9129249
Asia Pac J Clin Nutr. 2003;12(2):178-85
12810408
Rev Soc Bras Med Trop. 2002 Mar-Apr;35(2):133-41
12011921
Am J Clin Nutr. 1984 Nov;40(5):1090-5
6496388
Am J Clin Nutr. 1979 Feb;32(2):313-8
420128
Nutr Rev. 1998 Jan;56(1 Pt 2):S38-48
9481123
Am J Clin Nutr. 2000 Feb;71(2):507-13
10648265
World Health Organ Tech Rep Ser. 2002;912:i-vi, 1-57, back cover
12592987
J Trop Pediatr. 2000 Aug;46(4):239-41
10996988
Am J Clin Nutr. 1997 Sep;66(3):665-71
9280190
Ann Trop Paediatr. 2001 Mar;21(1):50-8
11284248
Am J Clin Nutr. 1979 Oct;32(10):2143-9
484533
Am J Trop Med Hyg. 1994 Oct;51(4):501-5
7943579
J Clin Endocrinol Metab. 1996 Aug;81(8):3123-6
8768885
J Nutr. 1999 Apr;129(4):872-7
10203563
Microbes Infect. 2003 Apr;5(5):405-11
12737996
Bull World Health Organ. 2001;79(5):415-22
11417037
Am J Trop Med Hyg. 1968 May;17(3):382-91
5690644
Acta Trop. 2006 Mar;97(3):270-83
16476400
Southeast Asian J Trop Med Public Health. 1980 Jun;11(2):245-9
7434075
Asia Pac J Clin Nutr. 2003;12(1):96-103
12737018
J Nutr. 2002 Sep;132(9 Suppl):2895S-2901S
12221267
Int J Vitam Nutr Res. 2008 Mar;78(2):51-6
18791972
J Trop Pediatr. 1995 Dec;41(6):334-7
8606439
Trans R Soc Trop Med Hyg. 2005 Sep;99(9):686-91
15992838
Asia Pac J Clin Nutr. 2002;11(2):88-91
12074186
Pediatr Dermatol. 2006 Jul-Aug;23(4):346-9
16918630
Am J Epidemiol. 2008 Sep 15;168(6):647-55
18669932
Trans R Soc Trop Med Hyg. 2007 Dec;101(12):1233-40
17936317