title: Prognostic indicators of poor outcome in horses with laminitis at a tertiary care hospital.
abstract: This retrospective study investigated the factors associated with a poor outcome (death by euthanasia or from other causes) in horses treated for laminitis at a tertiary care hospital. Cases (n = 247) were defined as patients with laminitis that were euthanized or that died of other causes during hospitalization. Controls (n = 344) were patients with laminitis that survived to be discharged from the hospital. In the final multivariate analysis, the factors significantly associated with an increased risk for death and their respective odds ratios (OR) were as follows: Thoroughbred (OR = 1.57); racehorse (OR = 1.76); treatment with flunixin meglumine (OR = 1.76); vascular pathology (OR = 2.12); distal displacement of the third phalanx (OR = 2.68); pneumonia (OR = 2.87); and lameness of Obel grade II (OR = 2.99), grade III (OR = 9.63), or grade IV (OR = 20.48). The use of glue-on shoes significantly reduced the risk for death (OR = 0.36).
authors.affiliation: The New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, 19348, USA. orsini@vet.upenn.edu
authors.forename: James A
authors.initials: JA
authors.lastname: Orsini
authors.forename: Corrina Snook
authors.initials: CS
authors.lastname: Parsons
authors.forename: Linda
authors.initials: L
authors.lastname: Capewell
authors.forename: Gary
authors.initials: G
authors.lastname: Smith
mesh_terms: D000818:Animals; D005260:Female; D005500:Follow-Up Studies; D005534:Foot Diseases / Q000401:mortality / Q000628:therapy / Q000662:veterinary*; D006724:Hoof and Claw / Q000473:pathology*; D006734:Horse Diseases / Q000401:mortality* / Q000628:therapy; D006736:Horses; D007249:Inflammation / Q000401:mortality / Q000628:therapy / Q000662:veterinary*; D007794:Lameness, Animal / Q000401:mortality* / Q000628:therapy; D008297:Male; D016017:Odds Ratio; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012775:Shoes; D016896:Treatment Outcome
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