title: Epoprostenol treatment for idiopathic pulmonary arterial hypertension in pregnancy.
abstract: Idiopathic pulmonary arterial hypertension is a rare condition associated with significant maternal mortality. We report the management of a 37-year-old multigravida with severe disease using epoprostenol, a multidisciplinary approach, and a planned delivery. Although the patient survived the pregnancy, her pulmonary function significantly worsened. Epoprostenol, a pulmonary vasodilator, should be considered when indicated during pregnancy. Neither fetal nor neonatal harm was identified.
authors.affiliation: Department of Obstetrics and Gynecology, University of Kentucky, Lexington, KY, USA. matt.garabedian@uky.edu
authors.forename: M J
authors.initials: MJ
authors.lastname: Garabedian
authors.forename: W F
authors.initials: WF
authors.lastname: Hansen
authors.forename: E A
authors.initials: EA
authors.lastname: Gianferrari
authors.forename: K Y
authors.initials: KY
authors.lastname: Lain
authors.forename: R Y
authors.initials: RY
authors.lastname: Fragneto
authors.forename: C L
authors.initials: CL
authors.lastname: Campbell
authors.forename: D C
authors.initials: DC
authors.lastname: Booth
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D017604:Cesarean Section, Repeat; D011464:Epoprostenol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D010348:Patient Care Team; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*
chemical_list: D000959:Antihypertensive Agents; D011464:Epoprostenol