title: Baimantuoluosides D-G, four new withanolide glucosides from the flower of Datura metel L.
abstract: In our search for bioactive anti-psoriasis compounds from the flower of Datura metel L, we isolated four new withanolide glucosides, baimantuoluosides D, E, F and G (1-4). The structures of the new compounds are (5alpha,6alpha,7beta,22R)-5,6,7,27-tetrahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (1), (5alpha,6beta,7alpha,22R)-5,6,7,27-tetrahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (2), (5alpha,6beta,7alpha,12beta,22R)-5,6,7,12,27-pentahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (3), and (5alpha,6beta,22R)-5,6,27-trihydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (4) on the basis of chemical and physicochemical evidence.
authors.affiliation: Heilongjiang University of Chinese Medicine, Harbin, 150040, China.
authors.forename: Bing-you
authors.initials: BY
authors.lastname: Yang
authors.forename: Yong-gang
authors.initials: YG
authors.lastname: Xia
authors.forename: Qiu-hong
authors.initials: QH
authors.lastname: Wang
authors.forename: De-qiang
authors.initials: DQ
authors.lastname: Dou
authors.forename: Hai-xue
authors.initials: HX
authors.lastname: Kuang
mesh_terms: D058530:Datura metel / Q000737:chemistry*; D035264:Flowers; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D054358:Withanolides / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D005960:Glucosides; D054358:Withanolides