[Development of alpha-glucosidase inhibitor from medicinal herbs].
Alpha-glucosidase inhibitor can reduce the postprandial hyperglycemia and have good effect on preventing and treating the diabetes and diabetic complication. Along with the application of acarbose which is a kind of alpha-glucosidase inhibitor, many research groups pay attention to the crude alpha-glucosidase inhibitor screened from the medicinal herbs in order to find new, safe, and effective medicine. The development of alpha-glucosidase inhibitor screened from the medicinal herbs and its evaluation in vivo and vitro as well as the varieties of the medicinal herbs that contain alpha-glucosidase inhibitor in recent 30 years were summarized in this paper.
Ji
Fang
F
School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Xiao
Guochun
G
Dong
Li
L
Ma
Zijiao
Z
Ni
Jingman
J
D002460:Cell Line; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D065089:Glycoside Hydrolase Inhibitors; D006801:Humans; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
D004791:Enzyme Inhibitors; D065089:Glycoside Hydrolase Inhibitors; D010936:Plant Extracts