title: (106)Ruthenium brachytherapy for ciliary recurrence with supraciliary effusion in retinoblastoma.
abstract: OBJECTIVE
  A 2-year-old boy with syndromic bilateral retinoblastoma resulting from a (del(13)(q12.3q14.3)) developed a recurrent tumor measuring 2.3 X 2.3 mm at the ora serrata 15 months following last treatment.
  
  
  METHODS
  Ultrasound biomicroscopy (UBM) revealed a mass invading the ciliary body 6.6 mm in diameter associated with a localized supraciliary effusion.
  
  
  RESULTS
  Complete tumor regression was achieved 1 month after brachytherapy with a (106)Ruthenium plaque. There was no recurrence at 16 months.
  
  
  CONCLUSIONS
  This is the first clinical demonstration of supraciliary effusion in recurrent retinoblastoma. Brachytherapy appears to be effective in the treatment of this type of recurrence.
authors.affiliation: Vitreo-Retina Services, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
authors.forename: Jay
authors.initials: J
authors.lastname: Chhablani
authors.forename: Antonio
authors.initials: A
authors.lastname: Romanzo
authors.forename: Aubin
authors.initials: A
authors.lastname: Balmer
authors.forename: Alessia
authors.initials: A
authors.lastname: Pica
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Gaillard
authors.forename: Raffaele
authors.initials: R
authors.lastname: Cozza
authors.forename: Raphaël
authors.initials: R
authors.lastname: Moeckli
authors.forename: Francis L
authors.initials: FL
authors.lastname: Munier
mesh_terms: D001918:Brachytherapy; D002675:Child, Preschool; D002872:Chromosome Deletion; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics; D002924:Ciliary Body / Q000000981:diagnostic imaging / Q000473:pathology / Q000528:radiation effects*; D006801:Humans; D008297:Male; D033401:Microscopy, Acoustic; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000532:radiotherapy*; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000235:genetics / Q000532:radiotherapy*; D012429:Ruthenium Radioisotopes / Q000627:therapeutic use*; D014604:Uveal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D012429:Ruthenium Radioisotopes