Mass spectrometry in high-throughput proteomics: ready for the big time.
Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success.
Nilsson
Tommy
T
Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada. tommy.nilsson@mcgill.ca
Mann
Matthias
M
Aebersold
Ruedi
R
Yates
John R
JR
Bairoch
Amos
A
Bergeron
John J M
JJ
D030562:Databases, Protein; D006801:Humans; D013058:Mass Spectrometry / Q000639:trends*; D020543:Proteome / Q000032:analysis*; D040901:Proteomics / Q000379:methods*; D011786:Quality Control; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D020543:Proteome
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