Recurrent myelitis after allogeneic stem cell transplantation. Report of two cases.
BACKGROUND
Allogeneic and autologous haematopoietic stem cell transplantation are established treatment options for haematological malignancies and may possibly be employed to treat a range of genetic and autoimmune diseases.


METHODS
We report two patients who developed an acute myelitis within their thoracic spinal cord after allogeneic stem cell transplantation. Myelitis in these patients was not related to graft versus host disease or immune reconstitution and was responsive to intravenous methylprednisolone and cyclophosphamide.


CONCLUSIONS
Myelitis is a possibly disabling consequence of haematopoietic stem cell transplantation.
Voss
Martin
M
Hertie Institute for Clinical Brain Research, Department of General Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany.
Bischof
Felix
F
D000368:Aged; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007938:Leukemia / Q000601:surgery; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009187:Myelitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D018696:Neuroprotective Agents / Q000627:therapeutic use; D012008:Recurrence; D013904:Thoracic Vertebrae
D018696:Neuroprotective Agents; D008775:Methylprednisolone
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