title: Asymmetric cortical degenerative syndromes: an integrated approach to clinical and imaging review.
abstract: BACKGROUND
  The term asymmetric cortical degenerative syndromes (ACDSs) refers to any brain afflictions that result in selective atrophy, particularly with an asymmetric pattern. Regardless of the etiology, the resulting compromised profile reflects the affected topography, which correlates with the clinical findings, more than any specific neuropathologic entity.
  
  
  RESULTS
  ACDS can represent a diagnostic challenge, because of an overlap of clinical manifestations, especially in the early stages. Magnetic resonance techniques are useful to understand nuclear medicine studies and to confirm areas of focal atrophy by providing anatomic details and allowing an accurate correlation with several different clinical settings.
  
  
  CONCLUSIONS
  This article demonstrates a practical neuroradiologic approach for ACDS, including optimized imaging analysis (magnetic resonance and nuclear medicine studies), which correlates their patterns with clinical and pathologic findings of the most relevant disorders.
authors.affiliation: Centro de Medicina Diagnóstica Fleury and Santa Casa de Misericórdia de São Paulo, SP, Brazil.
authors.forename: Antônio José
authors.initials: AJ
authors.lastname: da Rocha
authors.forename: Flávio Túlio
authors.initials: FT
authors.lastname: Braga
authors.forename: Carlos Jorge
authors.initials: CJ
authors.lastname: da Silva
authors.forename: Carlos
authors.initials: C
authors.lastname: Toyama
authors.forename: Hugo Pereira Pinto
authors.initials: HP
authors.lastname: Gama
authors.forename: Marco Antonio Conde
authors.initials: MA
authors.lastname: de Oliveira
mesh_terms: D001037:Aphasia / Q000473:pathology; D001921:Brain / Q000473:pathology*; D057174:Frontotemporal Lobar Degeneration / Q000145:classification / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D019636:Neurodegenerative Diseases / Q000473:pathology* / Q000503:physiopathology