title: [A case of hepatocellular carcinoma complicated with Caroli's disease].
abstract: A 29-year-old man was admitted with right hypochondralgia and fever. Markedly dilated bile ducts were observed, mainly in the right lobe of the liver. Based on both the clinical findings and imaging, we diagnosed Caroli's disease and choledochal cyst complicated with cholangitis. Hepatocellular carcinoma (HCC) was also observed in segment 3, and the tumor measured 4cm in diameter. The patient was successfully treated with hepatectomy of the right lobe, partial hepatectomy of the left lateral lobe, and bile duct reconstruction. A histopathological examination revealed moderately differentiated HCC without any components of cholangiocellular carcinoma (CCC). Although Caroli's disease is complicated with CCC, a case of Caroli's disease complicated with HCC, as in the present case, is quite rare and therefore is considered to be worthy of reporting.
authors.affiliation: Department of Internal Medicine, Isesaki Municipal Hospital, Japan. ijima0711@yahoo.co.jp
authors.forename: Masashi
authors.initials: M
authors.lastname: Ijima
authors.forename: Ryuya
authors.initials: R
authors.lastname: Shimoda
authors.forename: Kenji
authors.initials: K
authors.lastname: Katakai
authors.forename: Asako
authors.initials: A
authors.lastname: Seki
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Oshimoto
authors.forename: Jun
authors.initials: J
authors.lastname: Masuda
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Morinaga
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Satoru
authors.initials: S
authors.lastname: Kakizaki
authors.forename: Taido
authors.initials: T
authors.lastname: Arai
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D016767:Caroli Disease / Q000150:complications*; D002761:Cholangitis / Q000150:complications; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male