title: Development of genital warts after incident detection of human papillomavirus infection in young men.
abstract: Determining the rate at which men develop genital warts after infection with alpha genus human papillomavirus (HPV) types will provide important information for the design of prevention strategies. We conducted a cohort study of 18-21-year-old men who underwent triannual genital examinations. The 24-month cumulative genital wart incidence was 57.9% (95% confidence interval [CI], 38.1%-79.1%) among 46 men with incident detection of HPV-6 or HPV-11 infection, 2.0% (95% CI, 0.5%-7.9%) among 161 men with incident detection of infection with other HPV types, and 0.7% (95% CI, 0.2%-2.8%) among 331 men who tested negative for HPV. Our results suggest that genital warts are common after HPV-6 or HPV-11 infection in young men.
authors.affiliation: Departments of 1Epidemiology, and 6Harborview Medical Center, University of Washington, Seattle, WA 98104, USA.
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Arima
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Winer
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Feng
authors.forename: James P
authors.initials: JP
authors.lastname: Hughes
authors.forename: Shu-Kuang
authors.initials: SK
authors.lastname: Lee
authors.forename: Michael E
authors.initials: ME
authors.lastname: Stern
authors.forename: Sandra F
authors.initials: SF
authors.lastname: O'Reilly
authors.forename: Laura A
authors.initials: LA
authors.lastname: Koutsky
mesh_terms: D000293:Adolescent; D000328:Adult; D052685:Alphapapillomavirus; D015331:Cohort Studies; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000209:etiology* / Q000821:virology; D052140:Human papillomavirus 11; D052163:Human papillomavirus 6 / Q000502:physiology; D006801:Humans; D015994:Incidence; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications* / Q000453:epidemiology*; D012307:Risk Factors; D013997:Time Factors; D055815:Young Adult