title: [Efficacy of adepress (paroxetin) in generalized anxiety disorder].
abstract: The aim of the study was to evaluate efficacy of adepress (paroxetin) in different clinical variants of generalized anxiety disorder (GAD). Adepress was used as a monotherapy during 42 days. Patient's state was assessed using Hamilton anxiety scale (HAM-A) at baseline and every week thereafter. The study included 49 patients aged 36,2+/-8,2 years. Patients were stratified into two groups according to the predominance of somatic (24 cases) or cognitive (21 cases) anxiety. The efficacy of adepress was shown both in a separate GAD and in a GAD with comorbid psychopathology. The effect of the drug was seen in patients with somatic anxiety after 3-4 weeks and in patients with cognitive anxiety after 3-6 weeks.
authors.forename: V O
authors.initials: VO
authors.lastname: Chakhava
authors.forename: F S
authors.initials: FS
authors.lastname: Budtueva
authors.forename: R R
authors.initials: RR
authors.lastname: Borukaev
mesh_terms: D000293:Adolescent; D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008347:Manifest Anxiety Scale; D008875:Middle Aged; D017374:Paroxetine / Q000627:therapeutic use*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors