title: Severe coinfections of dengue and pandemic influenza A H1N1 viruses.
abstract: Here we report on 4 hospitalized patients with dengue-influenza virus coinfections. All patients were RT-PCR positive for dengue virus and pandemic influenza A H1N1. Clinical findings at presentation ranged from influenza-like illness to severe dengue. Clinical progression of the infections varied, but all developed dengue symptoms and had interstitial infiltrates. Three cases required intensive care management and 1 case was fatal.
authors.affiliation: Hospital Infantil Manuel de Jesús Rivera, Ministerio de Salud, Managua, Nicaragua.
authors.forename: Maria Angeles
authors.initials: MA
authors.lastname: Perez
authors.forename: Aubree
authors.initials: A
authors.lastname: Gordon
authors.forename: Felix
authors.initials: F
authors.lastname: Sanchez
authors.forename: Federico
authors.initials: F
authors.lastname: Narvaez
authors.forename: Gamaliel
authors.initials: G
authors.lastname: Gutierrez
authors.forename: Oscar
authors.initials: O
authors.lastname: Ortega
authors.forename: Andrea
authors.initials: A
authors.lastname: Nuñez
authors.forename: Eva
authors.initials: E
authors.lastname: Harris
authors.forename: Angel
authors.initials: A
authors.lastname: Balmaseda
mesh_terms: D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000821:virology*; D003716:Dengue Virus / Q000235:genetics / Q000302:isolation & purification*; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000821:virology*; D008297:Male; D020133:Reverse Transcriptase Polymerase Chain Reaction
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