title: [Regression of MALT lymphoma of the rectum after Helicobacter pylori eradication therapy in a patient negative for Helicobacter pylori].
abstract: A 53-year-old woman was referred to our hospital for further examination of a rectal polypoid lesion. Colonoscopy revealed a submucosal tumor in the rectum (Ra) and a diagnosis of MALT lymphoma was made on the histological examination of the biopsy specimens and Southern blot analysis of the immunoglobulin heavy chain gene rearrangement. Although the patient was negative for Helicobacter pylori, H. pylori eradication therapy was performed. Colonoscopy 3 months after the eradication therapy showed disappearance of the rectal tumor. H. pylori eradication appears to be a useful treatment for not only H. pylori-positive colonic MALT lymphoma but H. pylori-negative colonic MALT lymphoma.
authors.affiliation: Department of Gastroenterology, Miyagi Cancer Center, Japan. nomura-ei748@pref.miyagi.jp
authors.forename: Eiki
authors.initials: E
authors.lastname: Nomura
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Uchimi
authors.forename: Makoto
authors.initials: M
authors.lastname: Abue
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kon
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Noguchi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Masaki
authors.initials: M
authors.lastname: Suzuki
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Onodera
authors.forename: Hiroo
authors.initials: H
authors.lastname: Tateno
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ota
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000008:administration & dosage; D000658:Amoxicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D017291:Clarithromycin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D016480:Helicobacter pylori / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D064747:Lansoprazole; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy* / Q000382:microbiology; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D064747:Lansoprazole; D000658:Amoxicillin; D017291:Clarithromycin