title: [Pharmacotherapy of acute and chronic hearing loss].
abstract: The aetiology of acute hearing loss is mostly idiopathic like sudden sensorineural hearing loss and rarely infectious or vascular. Several studies and meta-analyses of pharmacotherapy are reviewed: In chronic tinnitus there is no indication for pharmacotherapy; sometimes a possible psychosomatic comorbidity has to be treated with psychopharmaceutical agents. Despite a low level of evidence treatment with steroids and initially plasma expanding infusions is recommended for acute tinnitus if there is no spontaneous remission. Intratympanic steroid therapy can be used as an alternative if there is severe hearing loss together with tinnitus.
authors.affiliation: Tinnitus-Klinik, Krankenhaus Bad Arolsen, Große Allee 50, 34454 Bad Arolsen. ghesse@tinnitus-klinik.net
authors.forename: G
authors.initials: G
authors.lastname: Hesse
authors.forename: A
authors.initials: A
authors.lastname: Laubert
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D006801:Humans; D013256:Steroids / Q000627:therapeutic use*; D014012:Tinnitus / Q000188:drug therapy*
chemical_list: D013256:Steroids
references.citation: Otolaryngol Head Neck Surg. 2007 Dec;137(6):950-2
references.pmid: 18036427
references.citation: Otol Neurotol. 2007 Jan;28(1):11-5
references.pmid: 17106432
references.citation: Otol Neurotol. 2007 Jun;28(4):455-8
references.pmid: 17529847
references.citation: J Negat Results Biomed. 2009 Feb 17;8:3
references.pmid: 19222841
references.citation: Arch Otolaryngol. 1980 Dec;106(12):772-6
references.pmid: 7002129
references.citation: HNO. 2006 Jan;54(1):9-15
references.pmid: 16132881
references.citation: Eur Arch Otorhinolaryngol. 2001 Nov;258(9):477-80
references.pmid: 11769996
references.citation: Audiol Neurootol. 2009;14(6):350-60
references.pmid: 19923805
references.citation: Dtsch Med Wochenschr. 2000 Mar 10;125(10):280-5
references.pmid: 10742824
references.citation: Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004739
references.pmid: 17253520
references.citation: HNO. 2008 Jul;56(7):694-700
references.pmid: 18560740
references.citation: Lancet. 2002 Dec 7;360(9348):1811-7
references.pmid: 12480357
references.citation: Arch Otolaryngol Head Neck Surg. 2007 Jun;133(6):573-81
references.pmid: 17576908
references.citation: Laryngorhinootologie. 2004 Mar;83(3):164-72
references.pmid: 15042481
references.citation: Otol Neurotol. 2009 Aug;30(5):676-80
references.pmid: 19574947
references.citation: Otol Neurotol. 2009 Feb;30(2):131-8
references.pmid: 19180674
references.citation: Otol Neurotol. 2010 Jan;31(1):25-30
references.pmid: 19940792
references.citation: Eur Arch Otorhinolaryngol. 2009 Jul;266(7):943-53
references.pmid: 18923838
references.citation: Otolaryngol Head Neck Surg. 2007 Jan;136(1):72-7
references.pmid: 17210337
references.citation: HNO. 2003 Dec;51(12):1005-11
references.pmid: 14647932
references.citation: Arch Otolaryngol Head Neck Surg. 2007 Jun;133(6):582-6
references.pmid: 17576909
references.citation: Laryngoscope. 2006 May;116(5):675-81
references.pmid: 16652071
references.citation: Laryngoscope. 2010 May;120(5):1011-21
references.pmid: 20422698
references.citation: Laryngol Rhinol Otol (Stuttg). 1985 Jul;64(7):347-50
references.pmid: 3875775
references.citation: Zhonghua Er Bi Yan Hou Ke Za Zhi. 2002 Feb;37(1):64-8
references.pmid: 12768798
references.citation: HNO. 2001 Feb;49(2):93-101
references.pmid: 11270201
references.citation: Laryngoscope. 2009 Feb;119(2):359-69
references.pmid: 19172627
references.citation: Otol Neurotol. 2007 Feb;28(2):157-70
references.pmid: 17255882
references.citation: HNO. 2000 Aug;48(8):621-3
references.pmid: 10994175
references.citation: Cochrane Database Syst Rev. 2006 Jan 25;(1):CD003998
references.pmid: 16437471
references.citation: HNO. 2000 Mar;48(3):182-8
references.pmid: 10768108
references.citation: HNO. 2010 May;58(5):445-51
references.pmid: 20182682