title: Hemorheologic profile in healthy women undergoing controlled ovarian stimulation.
abstract: We investigated the hemorheologic profile in 110 women undergoing controlled ovarian stimulation and provide evidence that smokers and women with body mass index>25 kg/m2 exhibit alterations of rheologic profile. A progressive increase of whole-blood viscosity throughout the ovarian stimulation cycle was observed; deformability and aggregation of erythrocytes decreased from baseline to the beginning of recombinant FSH administration, then remained unchanged throughout the next days; hematocrit mildly decreased during the last days of recombinant FSH administration; and fibrinogen and cholesterol levels decreased and increased, respectively, throughout the stimulation cycle.
authors.affiliation: Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy. cinzia.fatini@unifi.it
authors.forename: Cinzia
authors.initials: C
authors.lastname: Fatini
authors.forename: Lucia
authors.initials: L
authors.lastname: Mannini
authors.forename: Elena
authors.initials: E
authors.lastname: Sticchi
authors.forename: Maria Novella
authors.initials: MN
authors.lastname: Milanini
authors.forename: Gabriele
authors.initials: G
authors.lastname: Cioni
authors.forename: Agatina
authors.initials: A
authors.lastname: Alessandrello Liotta
authors.forename: Rosanna
authors.initials: R
authors.lastname: Abbate
authors.forename: Ivo
authors.initials: I
authors.lastname: Noci
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000187:drug effects; D006063:Chorionic Gonadotropin / Q000008:administration & dosage / Q000009:adverse effects; D004903:Erythrocyte Aggregation / Q000187:drug effects; D004907:Erythrocyte Deformability / Q000187:drug effects; D005260:Female; D005300:Fertility Agents, Female / Q000008:administration & dosage / Q000009:adverse effects; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage / Q000009:adverse effects; D018056:Hemorheology / Q000187:drug effects*; D006728:Hormones / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000628:therapy*; D016729:Leuprolide / Q000008:administration & dosage / Q000009:adverse effects; D010062:Ovulation Induction; D012307:Risk Factors; D020554:Sperm Injections, Intracytoplasmic; D014652:Vascular Diseases / Q000139:chemically induced / Q000453:epidemiology; D055815:Young Adult
chemical_list: D006063:Chorionic Gonadotropin; D005300:Fertility Agents, Female; D006728:Hormones; D005640:Follicle Stimulating Hormone; D016729:Leuprolide