Luteal phase estradiol versus luteal phase estradiol and antagonist protocol for controlled ovarian stimulation before in vitro fertilization in poor responders.
Luteal phase synchronization of follicular growth has been suggested as a means to improve ovarian response in low responders. We compared luteal E2 and antagonist (n=256) with luteal E2 only (n=57) before antagonist protocol in low responders. The addition of GnRH antagonist to luteal E2 for luteal suppression before ovarian stimulation for IVF does not improve IVF outcomes in poor responders.
Elassar
Alyaa
A
Center for Advanced Reproductive Services, University of Connecticut Health Center, Farmington, Connecticut 06030-6224, USA.
Mann
Jessica Salas
JS
Engmann
Lawrence
L
Nulsen
John
J
Benadiva
Claudio
C
D000328:Adult; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004958:Estradiol / Q000097:blood*; D004965:Estrogen Antagonists / Q000008:administration & dosage*; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008183:Luteal Phase / Q000502:physiology*; D006080:Ovarian Follicle / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome
D004965:Estrogen Antagonists; D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D005640:Follicle Stimulating Hormone