title: Sensitive and selective localized surface plasmon resonance light-scattering sensor for Ag+ with unmodified gold nanoparticles.
abstract: A novel localized surface plasmon resonance (LSPR) light-scattering sensor for Ag(+) was developed with unmodified gold nanoparticles (AuNPs), based upon the specific recognition property of Ag(+) with a cytosine-cytosine mismatched base pair. The addition of Ag(+) induced the oligonucleotide 5'-TAC ATA CAT ACT ATC TAT CTA-3' to be desorbed from the surface of the AuNPs, resulting in the aggregation of AuNPs, accompanied by a dramatic enhancement of the LSPR light-scattering intensity. The enhancement of LSPR light-scattering intensity was proportional to the concentration of Ag(+) in the range of 0.13-1.12 μM, with a limit of detection of 62.0 nM. The results were also proved by a colorimetric method. Furthermore, this method can provide satisfactory results for the determination of Ag(+) in water samples and industrial products.
authors.affiliation: School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
authors.forename: Chengke
authors.initials: C
authors.lastname: Wu
authors.forename: Cen
authors.initials: C
authors.lastname: Xiong
authors.forename: Linjing
authors.initials: L
authors.lastname: Wang
authors.forename: Chongchong
authors.initials: C
authors.lastname: Lan
authors.forename: Liansheng
authors.initials: L
authors.lastname: Ling
mesh_terms: D020137:Base Pair Mismatch; D003596:Cytosine / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008027:Light; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009841:Oligonucleotides / Q000737:chemistry; D012542:Scattering, Radiation; D012834:Silver / Q000032:analysis*; D020349:Surface Plasmon Resonance / Q000379:methods*; D013696:Temperature; D014867:Water / Q000737:chemistry
chemical_list: D009841:Oligonucleotides; D014867:Water; D012834:Silver; D006046:Gold; D003596:Cytosine