Associated factors for a hyperechogenic pancreas on endoscopic ultrasound.
OBJECTIVE
To identify the associated risk factors for hyperechogenic pancreas (HP) which may be observed on endoscopic ultrasound (EUS) and to assess the relationship between HP and obesity.


METHODS
From January 2007 to December 2007, we prospectively enrolled 524 consecutive adults who were scheduled to undergo EUS. Patients with a history of pancreatic disease or with hepatobiliary or advanced gastrointestinal cancer were excluded. Finally, 284 patients were included in the analyses. We further analyzed the risk of HP according to the categories of visceral adipose tissue (VAT) and subcutaneous adipose tissue in 132 patients who underwent abdominal computed tomography scans.


RESULTS
On univariate analysis, age older than 60 years, obesity (body mass index > 25 kg/m(2)), fatty liver, diabetes mellitus, hypertension and hypercholesterolemia were identified as risk factors associated with HP (P < 0.05). On multivariate analysis, fatty liver [P = 0.008, odds ratio (OR) = 2.219], male gender (P = 0.013, OR = 2.636), age older than 60 years (P = 0.001, OR = 2.874) and hypertension (P = 0.044, OR = 2.037) were significantly associated with HP. In the subgroup analysis, VAT was a statistically significant risk factor for HP (P = 0.010, OR = 5.665, lowest quartile vs highest quartile).


CONCLUSIONS
HP observed on EUS was associated with fatty liver, male gender, age older than 60 years, hypertension and VAT.
Choi
Cheol Woong
CW
Department of Internal Medicine, Pusan National University School of Medicine and the Medical Research Institute, Pusan National University Hospital, 1-10 Ami-dong, Seo-Gu, Busan 602-739, South Korea.
Kim
Gwang Ha
GH
Kang
Dae Hwan
DH
Kim
Hyung Wook
HW
Kim
Dong Uk
DU
Heo
Jeong
J
Song
Geun Am
GA
Park
Do Youn
DY
Kim
Suk
S
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
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