title: Original and efficient synthesis of D-cycloserine.
abstract: A simple pathway for the preparation of D-cycloserine is presented. The intermediates and D-cycloserine were characterized by FT-IR, (1)H-NMR spectra and elemental analysis. D-Cycloserine can inhibit the growth of Mycobacterium tuberculosis and can be used as a second-line drug for the treatment of tuberculosis, especially for the use in developing countries.
authors.affiliation: School of Chemical Engineering, Shandong Institute of Light Industry, Jinan, PR China.
authors.forename: Xiaomeng
authors.initials: X
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Meng
authors.forename: Hongdong
authors.initials: H
authors.lastname: Duan
authors.forename: Lizhen
authors.initials: L
authors.lastname: Wang
authors.forename: Shixiao
authors.initials: S
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Dawei
authors.initials: D
authors.lastname: Qin
mesh_terms: D003523:Cycloserine / Q000138:chemical synthesis*; D003906:Developing Countries; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D017550:Spectroscopy, Fourier Transform Infrared; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D003523:Cycloserine