title: Diastereoselective conjugate addition of organocuprates to chiral N-enoyl oxazolidinethiones.
abstract: Addition of organocuprates, generated in situ using an excess of a 1:2 mixture of CuI·DMS and Grignard reagent, to N-enoyl oxazolidinethiones in the presence of excess TMSI gave preferentially the anti diastereomer where the addition took place when the conformation of the substrate was syn-s-cis. The reaction was investigated with indene-based and three different phenyl glycine derived oxazolidinethiones.
authors.affiliation: Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Pue. 72570, Mexico.
authors.forename: Rocío
authors.initials: R
authors.lastname: Sabala
authors.forename: Luis
authors.initials: L
authors.lastname: Hernández-García
authors.forename: Aurelio
authors.initials: A
authors.lastname: Ortiz
authors.forename: Moisés
authors.initials: M
authors.lastname: Romero
authors.forename: Horacio F
authors.initials: HF
authors.lastname: Olivo
mesh_terms: D003300:Copper / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013871:Thiones / Q000138:chemical synthesis*
chemical_list: D009942:Organometallic Compounds; D010080:Oxazoles; D013871:Thiones; D003300:Copper