title: N-of-1 clinical trials should be incorporated into clinical practice.
abstract: N-of-1 clinical trials have the potential to contribute to individual patient management and to the accrual of important information about populations. Incorporating these studies into clinical practice will require creative thinking so as to maintain rigor without excessive disruption of routine care.
authors.affiliation: Johnson & Johnson Pharmaceutical Research and Development, 1125 Trenton-Harbourton Road, Titusville, NJ 08560, USA. jberlin@its.jnj.com
authors.forename: Jesse A
authors.initials: JA
authors.lastname: Berlin
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards*; D006751:Hospital Information Systems / Q000706:statistics & numerical data*; D006801:Humans; D015201:Meta-Analysis as Topic; D018802:Patient-Centered Care; D057285:Precision Medicine; D012107:Research Design / Q000592:standards*