Possible role of alpha-lipoic acid in the treatment of peripheral nerve injuries.
Recent findings on the antioxidant effects of pretreatment with α-lipoic acid (α-LA) on the crush injury of rat sciatic nerve confirm the possible usefulness of α-LA administration in humans with peripheral nerve injuries. We discussed this issue in relation with our recent results in which the combined employment of α-LA and γ-linolenic acid with a rehabilitation program for six weeks reduced sensory symptoms and neuropathic pain in patients with compressive radiculopathy syndrome from disc-nerve root conflict in comparison with patients submitted to rehabilitation program alone for six weeks.
Ranieri
Maurizio
M
Department of Physical Medicine and Rehabilitation, University of Foggia, Foggia, Italy. a.santamato@unifg.it.
Sciuscio
Manuela
M
Cortese
Annamaria
A
Stasi
Marilena
M
Panza
Francesco
F
Megna
Marisa
M
Fiore
Pietro
P
Santamato
Andrea
A
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