Issues of recruitment and rationale for conducting clinical trials on mutans streptococci suppression in mothers.
The aims of this study are (1) to describe issues related to recruitment of mothers participating in a clinical trial of transmission of mutans streptococci (MS) from mother to child in Bauru, Brazil and (2) to perform cross-cultural and temporal comparisons of levels of infection of the MS in mothers of Bauru. A total of 1422 mothers were visited at their domiciles. Cutoff levels for the MS were established at ≥10(5) CFU/mL saliva. The main reason for a mother not enrolling was not being highly infected by the MS, yet 76% of mothers presented with levels ≥10(5) CFU/mL saliva. Recent studies in industrialized countries showed a negative coefficient for linear tests indicating significant decline overtime in the levels of MS in mothers. Intercountry comparisons for mothers' salivary levels of the MS with the Bauru study as the reference revealed significant differences with studies conducted in the last two decades.
Bretz
Walter A
WA
College of Dentistry, New York University, NY 10010, USA.
Rosa
Odila P S
OP
Silva
Salete M B
SM
Corby
Patricia
P
Weissfeld
Lisa
L
Loesche
Walter J
WJ
J Dent Res. 2000 Mar;79(3):882-7
10765964
J Am Dent Assoc. 1998 Jul;129(7):871-7
9685762
Arch Oral Biol. 1994 Oct;39(10):907-11
7741661
Eur J Oral Sci. 1996 Aug;104(4 ( Pt 2)):426-9
8930593
Aust Dent J. 1985 Apr;30(2):96-8
3862382
Oral Health Prev Dent. 2005;3(3):151-7
16355648
Braz Oral Res. 2005 Oct-Dec;19(4):249-55
16491251
Arch Oral Biol. 1984;29(6):453-60
6589988
Proc Finn Dent Soc. 1988;84(5-6):271-7
3227019
Arch Oral Biol. 1984;29(11):879-83
6596034
Scand J Dent Res. 1982 Apr;90(2):102-8
6951251
Swed Dent J. 2005;29(2):71-9
16035350
J Clin Microbiol. 1989 Feb;27(2):274-8
2563384
Cancer Nurs. 2003 Oct;26(5):376-84; quiz 385-6
14710799
Community Dent Oral Epidemiol. 1995 Apr;23(2):65-8
7781301
Cad Saude Publica. 2005 Sep-Oct;21(5):1383-91
16158143
J Dent Res. 1989 Mar;68(3):468-71
2921389
Caries Res. 1998;32(5):319-23
9701655
Infect Immun. 1988 Dec;56(12):3216-20
3182079
Scand J Dent Res. 1987 Feb;95(1):13-7
3470893
Community Dent Oral Epidemiol. 1993 Jun;21(3):136-42
8348786
Arch Oral Biol. 1975 Nov;20(11):725-30
1061524
Arch Oral Biol. 1973 Nov;18(11):1357-64
4518755