title: Takotsubo syndrome in a newborn.
abstract: Takotsubo syndrome is characterized by transient and regional left ventricular dysfunction, which does not correspond anatomically to coronary distribution, without obstructive coronary lesions and frequently follows episodes of emotional or physical stress. The authors present a case of takotsubo syndrome, complicated by acute heart failure and functional severe mitral regurgitation, in a newborn after fetal distress caused by the umbilical cord being twisted around the chest and neck. In newborns after birth asphyxia, left ventricular dysfunction has been reported as global and due to ischemia. In this case, the transient and regional left ventricular dysfunction involving segments of multiple epicardial coronary territories, with associated hyperkinesis of the ventricular septum and basal segments of other walls, could have been caused by delivery stress with catecholamine-mediated cardiac toxicity.
authors.affiliation: Intensive Cardiac Care Unit, Vito Fazzi Hospital, Lecce, Italy. cosimo.greco@tin.it
authors.forename: Cosimo Angelo
authors.initials: CA
authors.lastname: Greco
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Rito
authors.forename: Maurizio
authors.initials: M
authors.lastname: Petracca
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Garzya
authors.forename: Mario
authors.initials: M
authors.lastname: Donateo
authors.forename: Francesco
authors.initials: F
authors.lastname: Magliari
mesh_terms: D003937:Diagnosis, Differential; D018618:Echocardiography, Doppler, Color; D004562:Electrocardiography; D006333:Heart Failure / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D054549:Takotsubo Cardiomyopathy / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy