title: Low-grade chondrosarcoma of bone: experiences from the Vienna Bone and Soft Tissue Tumour Registry.
abstract: In a retrospective single-centre study, 70 low-grade chondrosarcoma (LCS) (31 female/39 male patients with a mean age of 40 years) were reviewed to evaluate surgical management. The mean overall follow-up was 81 months (median: 73 months, range: 6-317 months). Seventeen lesions (24.3%) in the trunk and 53 (75.7%) in the extremities were treated by curettage (48.6%) or resection (51.5%). Local recurrence occurred in eight patients (11.4%) 18 months postoperatively (median: 18 months, range: 0-41 months). Recurrence-free survival was significantly better for patients with extremity lesions compared to truncal lesions, but was not affected by resection margin. The anatomical site "trunk" and an "intralesional" resection margin had a significant independent prognostic influence in multivariate analysis. Curettage with local adjuvants is a viable treatment option for most extremity LCS. In truncal LCS wide resection is recommended despite a potentially higher complication rate.
authors.affiliation: Medical University of Vienna Department of Orthopaedic Surgery, Vienna General Hospital, Waehringer Guertel 18-20, 1090, Vienna, Austria. philipp.funovics@meduniwien.ac.at
authors.forename: Philipp T
authors.initials: PT
authors.lastname: Funovics
authors.forename: Joannis
authors.initials: J
authors.lastname: Panotopoulos
authors.forename: Manuel
authors.initials: M
authors.lastname: Sabeti-Aschraf
authors.forename: Farshid
authors.initials: F
authors.lastname: Abdolvahab
authors.forename: Josef M
authors.initials: JM
authors.lastname: Funovics
authors.forename: Susanna
authors.initials: S
authors.lastname: Lang
authors.forename: Rainer I
authors.initials: RI
authors.lastname: Kotz
authors.forename: Martin
authors.initials: M
authors.lastname: Dominkus
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001317:Austria / Q000453:epidemiology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D002648:Child; D002813:Chondrosarcoma / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D012042:Registries; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult
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