[Upper urinary tract infections in adults: about 261 episodes].
BACKGROUND
Upper urinary tract infections are frequent. Escherichia coli is the main pathogen identified from community acquired infections.


OBJECTIVE
We aim to study epidemiologic, clinical and bacterial features of this infection.


METHODS
We identified 261 episodes that occurred in 241 patients. They were 213 females and 48 males aged of 48.75 years. Enterobacteriaceae were the main pathogens isolated in 93.5%: E. coli in 73.3% and Klebsiella pneumoniae in 15.3%. E. coli sensitivity was of 30% for amoxicillin, 98% for cefotaxim, 96% for gentamicin, 90% for ciprofloxacin and 56% for co-trimoxazole. Anterior antibiotic use was associated with low E. coli sensitivity mainly with fluoroquinolones (96 vs 77%) and co-trimoxazole (62 vs 43%). This enhances the role of antibiotic pressure on the resistance emergence.


CONCLUSIONS
the reasonable use of antibiotics is necessary to limit resistance extent.
Abdelmalek
Rim
R
Service des Maladies Infectieuses, Hôpital La Rabta, Tunis, Tunisie.
Kilani
Badreddine
B
Kanoun
Fakher
F
Ammari
Lamia
L
Benaissa
Hanene Tiouiri
HT
Goubontini
Ahmed
A
Zouiten
Faycal
F
Chaabane
Taoufik Ben
TB
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology*; D055815:Young Adult
D000900:Anti-Bacterial Agents