title: A study on the validity of quantitative ultrasonic measurement used the bone mineral density values on dual-energy X-ray absorptiometry in young and in middle-aged or older women.
abstract: The influence of age and physique on dual-energy X-ray absorptiometry (DXA) and quantitative ultrasound (QUS) was investigated in young, middle-aged, and older women. The validity of the bilateral calcaneal QUS values was investigated regarding the bone mineral density (BMD) values on DXA of the lumbar spine, left femoral neck, and left femur as the optimal standards. The subjects were 55 young women (19.6 +/- 1.0 years), and 152 middle-aged and older women (62.9 +/- 7.2 years). The BMD on DXA was significantly correlated with the bone strength on QUS in both young and middle-aged or older women, but the positive likelihood ratios of the standard QUS values recommended by the manufacturer to the optimum standards on DXA were low, suggesting that osteoporosis cannot be diagnosed or predicted by use of the QUS method. Combination with DXA is necessary, such as primary screening by QUS followed by secondary screening by DXA.
authors.affiliation: Department of Public Health, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukakecho, Toyoake, Aichi, 470-1192, Japan. iida@fujita-hu.ac.jp
authors.forename: Tadayuki
authors.initials: T
authors.lastname: Iida
authors.forename: Chiho
authors.initials: C
authors.lastname: Chikamura
authors.forename: Satomi
authors.initials: S
authors.lastname: Aoi
authors.forename: Hiromi
authors.initials: H
authors.lastname: Ikeda
authors.forename: Yuko
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Oguri
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ono
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katada
authors.forename: Fumiko
authors.initials: F
authors.lastname: Ishizaki
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D000368:Aged; D000375:Aging / Q000502:physiology; D015519:Bone Density; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results; D014463:Ultrasonography; D055815:Young Adult
references.citation: JAMA. 1992 Aug 12;268(6):760-5
references.pmid: 1386391
references.citation: J Bone Miner Metab. 2004;22(5):486-90
references.pmid: 15316870
references.citation: J Gen Intern Med. 1994 Feb;9(2):71-4
references.pmid: 8164080
references.citation: JAMA. 1994 Feb 2;271(5):385-8
references.pmid: 8283588
references.citation: Am J Med. 1987 Feb;82(2):231-5
references.pmid: 2880504
references.citation: J Bone Miner Metab. 2004;22(3):248-53
references.pmid: 15108067
references.citation: JAMA. 1993 Sep 8;270(10):1242-6
references.pmid: 8355389
references.citation: Calcif Tissue Int. 1992 Sep;51(3):169-72
references.pmid: 1422959
references.citation: Arch Neurol. 1978 Aug;35(8):533-7
references.pmid: 666614
references.citation: Osteoporos Int. 2001;12(7):538-47
references.pmid: 11527050
references.citation: Osteoporos Int. 1994 Jul;4(4):220-5
references.pmid: 7949752
references.citation: Osteoporos Int. 1993 Sep;3(5):249-54
references.pmid: 8400606
references.citation: JAMA. 1992 May 20;267(19):2645-8
references.pmid: 1573754
references.citation: JAMA. 1993 Nov 10;270(18):2218-21
references.pmid: 8411607
references.citation: Clin Orthop Relat Res. 2007 Feb;455:3-5
references.pmid: 17340682
references.citation: J Biomech. 1987;20(10):979-86
references.pmid: 3693379
references.citation: Calcif Tissue Int. 1992 Mar;50(3):199-202
references.pmid: 1617492
references.citation: Eng Med. 1984 Apr;13(2):89-91
references.pmid: 6540216
references.citation: Calcif Tissue Int. 1997 Jan;60(1):2-7
references.pmid: 9030471
references.citation: Calcif Tissue Int. 1991 Aug;49(2):107-11
references.pmid: 1913288
references.citation: Radiat Med. 2007 May;25(4):148-54
references.pmid: 17514365