Sensitive determination of pesticides residues in wine samples with the aid of single-drop microextraction and response surface methodology.
The multi-residue trace-level determination of six pesticides (diazinon, dimethoate, chlorpyrifos, vinclozolin, fenthion and quinalphos) in wine samples, after their single-drop microextraction (SDME) is presented herein. The extraction procedure was optimized using the multivariate optimization approach following a two-stage process. The first screening experimental design brought out the significant parameters and was followed by a central composite design (CCD) experiment, which revealed the simultaneous effect of the significant factors affecting the SDME process. High level of linearity for all target analytes was recorded with r(2) ranging between 0.9978 and 0.9999 while repeatability (intra-day) and reproducibility (inter-day) varied from 5.6% to 7.4% and 4.9% to 12.5%, respectively. Limits of detection (LODs) and limits of quantification (LOQs) were found to range in the low microg L(-1) level. In general, the developed methodology presented simplicity and enhanced sensitivity, rendering it appropriate for routine wine screening purposes.
Garbi
Aimilia
A
Department of Chemistry, University of Ioannina, Ioannina 451 10, Greece.
Sakkas
Vasilios
V
Fiamegos
Yiannis C
YC
Stalikas
Constantine D
CD
Albanis
Triantafyllos
T
D057230:Limit of Detection; D010573:Pesticide Residues / Q000032:analysis*; D013499:Surface Properties; D014920:Wine / Q000032:analysis*
D010573:Pesticide Residues