title: Characterizing changes in kidney and renal pelvis cancer incidence from 1998 to 2006 in the United States.
abstract: In this study, we characterize the changes in kidney and renal pelvis cancer (RCC) from 1998 to 2006 in the United States. The goal is to examine variations in stage and treatments. In addition, we explore changes in risk factors that have occurred over the same period. Data on over 20,000 patients diagnosed with RCC in National Cancer Data Base were used for the study. We investigated the changes in stage and treatment rates based on race, gender and age at diagnosis from 1998 to 2006. Changes in smoking, obesity and hypertension rates over the period were examined for comparison. The increase in RCC incidence rates from 1998 to 2006 was almost entirely a result of increases in stage I. Increases for blacks were proportionally higher than whites. Obesity and hypertension increased over the period but smoking declined. In terms of treatment, there was an increase in surgery cases primarily for stage I. There were no significant differences in trends based on gender, although rates in men were 65% greater than in women. The mean age at diagnosis was stable for stages I-IV. There are increased incidences of renal tumors, particularly stage I renal cancer among blacks and whites from 1998 to 2006. Patients were more likely to undergo surgical therapy for these tumors.
authors.affiliation: University of Alabama at Birmingham, 1530 3rd Ave South, Birmingham, Al 35294, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Knox
authors.forename: Janet L
authors.initials: JL
authors.lastname: Colli
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000453:epidemiology* / Q000473:pathology; D007682:Kidney Pelvis; D008297:Male; D009367:Neoplasm Staging; D012307:Risk Factors; D013997:Time Factors; D014481:United States / Q000453:epidemiology
references.citation: Cancer Epidemiol Biomarkers Prev. 1996 Jan;5(1):17-21
references.pmid: 8770461
references.citation: Br J Urol. 1989 Feb;63(2):135-40
references.pmid: 2702397
references.citation: N Engl J Med. 1996 Nov 21;335(21):1552-8
references.pmid: 8900087
references.citation: J Urol. 2009 Oct;182(4):1271-9
references.pmid: 19683266
references.citation: Cancer Res. 1992 Jan 15;52(2):254-7
references.pmid: 1728398
references.citation: J Urol. 2006 Dec;176(6 Pt 1):2353-8
references.pmid: 17085101
references.citation: Urol Oncol. 2004 Nov-Dec;22(6):478-84
references.pmid: 15610865
references.citation: BJU Int. 2009 Apr;103(7):889-93
references.pmid: 19021607
references.citation: JAMA. 1999 May 5;281(17):1628-31
references.pmid: 10235157
references.citation: CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96
references.pmid: 18287387
references.citation: Hypertension. 2008 Nov;52(5):818-27
references.pmid: 18852389
references.citation: JAMA. 2003 Jul 9;290(2):199-206
references.pmid: 12851274
references.citation: Am J Epidemiol. 2000 Aug 1;152(3):272-8
references.pmid: 10933274
references.citation: Eur J Cancer Prev. 2002 Apr;11(2):171-8
references.pmid: 11984136
references.citation: Urology. 1998 Feb;51(2):203-5
references.pmid: 9495698
references.citation: Int J Cancer. 2006 Feb 1;118(3):728-38
references.pmid: 16094628
references.citation: Scand J Urol Nephrol. 2002;36(6):414-8
references.pmid: 12623504
references.citation: J Urol. 2008 May;179(5):1704-8
references.pmid: 18343443
references.citation: J Clin Oncol. 2007 Aug 20;25(24):3589-95
references.pmid: 17704406