Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy.
Kumar
Ashutosh
A
Abteilung für NMR-basierte Strukturbiologie, Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg 11, 37077 Göttingen, Germany.
Heise
Henrike
H
Blommers
Marcel J J
MJ
Krastel
Philipp
P
Schmitt
Esther
E
Petersen
Frank
F
Jeganathan
Siva
S
Mandelkow
Eva-Maria
EM
Carlomagno
Teresa
T
Griesinger
Christian
C
Baldus
Marc
M
D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D034261:Epothilones / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D008870:Microtubules / Q000378:metabolism* / Q000648:ultrastructure; D008958:Models, Molecular; D009231:Myxococcales / Q000737:chemistry; D009369:Neoplasms / Q000188:drug therapy; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D014404:Tubulin / Q000378:metabolism; D050257:Tubulin Modulators / Q000302:isolation & purification / Q000494:pharmacology*
D000970:Antineoplastic Agents; D034261:Epothilones; D014404:Tubulin; D050257:Tubulin Modulators; C093788:epothilone B