title: Home telemonitoring of non-invasive ventilation decreases healthcare utilisation in a prospective controlled trial of patients with amyotrophic lateral sclerosis.
abstract: BACKGROUND
  Non-invasive ventilation (NIV) is an efficient method for treating respiratory failure in patients with amyotrophic lateral sclerosis (ALS). However, it requires a process of adaptation not always achieved due to poor compliance. The role of telemonitoring of NIV is not yet established.
  
  
  OBJECTIVE
  To test the advantage of using modem communication in NIV of ALS patients.
  
  
  METHODS
  Prospective, single blinded controlled trial. Population and methods According to their residence, 40 consecutive ventilated ALS patients were assigned to one of two groups: a control group (G1, n=20) in which compliance and ventilator parameter settings were assessed during office visits; or an intervention group (G2, n=20) in which patients received a modem device connected to the ventilator. The number of office and emergency room visits and hospital admissions during the entire span of NIV use and the number of parameter setting changes to achieve full compliance were the primary outcome measurements.
  
  
  RESULTS
  Demographic and clinical features were similar between the two groups at admission. No difference in compliance was found between the groups. The incidence of changes in parameter settings throughout the survival period with NIV was lower in G2 (p<0.0001) but it was increased during the initial period needed to achieve full compliance. The number of office or emergency room visits and inhospital admissions was significantly lower in G2 (p<0.0001). Survival showed a trend favouring G2 (p=0.13).
  
  
  CONCLUSIONS
  This study shows that telemonitoring reduces health care utilisation with probable favourable implications on costs, survival and functional status.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Santa Maria Hospital, Lisbon, Portugal.
authors.forename: Anabela
authors.initials: A
authors.lastname: Pinto
authors.forename: José Pedro
authors.initials: JP
authors.lastname: Almeida
authors.forename: Susana
authors.initials: S
authors.lastname: Pinto
authors.forename: João
authors.initials: J
authors.lastname: Pereira
authors.forename: António Gouveia
authors.initials: AG
authors.lastname: Oliveira
authors.forename: Mamede
authors.initials: M
authors.lastname: de Carvalho
mesh_terms: D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000401:mortality; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006699:Home Care Services; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010865:Pilot Projects; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000209:etiology* / Q000401:mortality / Q000628:therapy*; D016037:Single-Blind Method; D017216:Telemedicine / Q000379:methods*; D016896:Treatment Outcome