Functional association of interleukin-18 gene -607 C/A promoter polymorphisms with endometriosis.
This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607∗A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis.
Ayaz
Lokman
L
Department of Biochemistry, School of Medicine, Mersin University, Mersin, Turkey.
Çelik
Sevim Karakaş
SK
Çayan
Filiz
F
Aras-Ateş
Nurcan
N
Tamer
Lülüfer
L
D000328:Adult; D004715:Endometriosis / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D020382:Interleukin-18 / Q000235:genetics*; D008875:Middle Aged; D012150:Polymorphism, Restriction Fragment Length; D011401:Promoter Regions, Genetic / Q000235:genetics; D012307:Risk Factors
D020382:Interleukin-18