[Nora's lesion. Discussion of a rare bone proliferation].
Nora's lesion, also known as "bizarre parosteal osteochondromatous proliferation" (BPOP), was first described in 1983 by the pathologist Nora. This lesion is defined as a proliferation of the bone. In most cases the lesion emanates from the intact cortical substance of short bones. It used to be assigned to reactive, heterotopic ossifications. More recent publications described constant genetic alterations supposing a tumorous genesis. Nora lesions are mostly found in the third or fourth decade of life; a preference of sexes is not described in the literature. They are characterized by a typical appearance in radiological diagnostics, but the diagnosis is ultimately determined by histopathological examination. Surgical resection is the therapy of choice.We report the case of a 29-year-old patient with an undetermined proliferation of the proximal ulna. The diagnosis of a Nora's lesion was made. The therapeutic approach, differential diagnosis and corresponding literature are presented and discussed.
Adler
D
D
Orthopädische Klinik und Poliklinik, Universität Leipzig, Liebigstrasse 20, 04103, Leipzig.
Aigner
T
T
von Salis-Soglio
G
G
Gutberlet
M
M
Heyde
C-E
CE
D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015831:Osteochondroma / Q000000981:diagnostic imaging* / Q000601:surgery*; D011859:Radiography; D035583:Rare Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D014457:Ulna / Q000000981:diagnostic imaging* / Q000601:surgery*
Am J Surg Pathol. 1993 Jul;17(7):691-7
8317609
Skeletal Radiol. 2001 May;30(5):282-5
11407720
J Orthop Sci. 2006 Oct;11(5):529-32
17013744
Am J Surg Pathol. 2004 Aug;28(8):1033-9
15252309
Am J Surg Pathol. 1983 Apr;7(3):245-50
6837834
Praxis (Bern 1994). 2006 Apr 26;95(17):681-3
16686325
Virchows Arch. 2005 Jul;447(1):99-102
15926071
Skeletal Radiol. 2006 Jul;35(7):497-502
16602017
Z Orthop Unfall. 2007 May-Jun;145(3):327-30
17607632
Hum Pathol. 2004 Sep;35(9):1063-9
15343507
Skeletal Radiol. 2001 Apr;30(4):192-8
11392292
Saudi Med J. 2006 Dec;27(12):1915-6
17143377
Hum Pathol. 2002 Dec;33(12):1205-10
12514790
Eur Radiol. 2006 Jan;16(1):108-23
15834724
Skeletal Radiol. 2007 Sep;36(9):829-34
17437102
Skeletal Radiol. 1992;21(5):301-3
1502582
Skeletal Radiol. 2006 Nov;35(11):805-13
17019614