title: Pandemic influenza A (H1N1) in HIV-1-infected patients.
abstract: OBJECTIVE
  To characterize the clinical presentation, course and mortality of pandemic influenza in HIV-1-infected patients in Santiago, Chile.
  
  
  METHODS
  Prospective observational study.
  
  
  RESULTS
  Thirty patients were included (three hospitalized), 93% were on HAART, mean CD4(+) cell count was 423 cells/μl and viral load was undetectable in 77% of patients. All patients had fever, 90% had cough, 80% had myalgias, 70% had pharyngeal congestion, 47% had coryza, 47% had odynophagia, 37% had headache and 23% had vomiting. Four patients developed pneumonia. All patients received antiviral therapy and no patient died.
  
  
  CONCLUSIONS
  HIV patients infected by the new influenza A pandemic (H1N1) virus behave similarly to the general population.
authors.affiliation: Department of Medicine, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. cape@med.puc.cl
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Perez
authors.forename: Maria I
authors.initials: MI
authors.lastname: Dominguez
authors.forename: Maria E
authors.initials: ME
authors.lastname: Ceballos
authors.forename: Cristina
authors.initials: C
authors.lastname: Moreno
authors.forename: Jaime A
authors.initials: JA
authors.lastname: Labarca
authors.forename: Ricardo
authors.initials: R
authors.lastname: Rabagliati
authors.forename: Patricia
authors.initials: P
authors.lastname: Vasquez
authors.forename: Martin
authors.initials: M
authors.lastname: Lasso
authors.forename: Michel
authors.initials: M
authors.lastname: Serri
mesh_terms: D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D002677:Chile; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects / Q000472:pathogenicity*; D007251:Influenza, Human / Q000188:drug therapy / Q000821:virology*; D008297:Male; D008875:Middle Aged; D058873:Pandemics; D011446:Prospective Studies; D019562:Viral Load