X-ray fluorescence camera for imaging of iodine media in vivo.
X-ray fluorescence (XRF) analysis is useful for measuring density distributions of contrast media in vivo. An XRF camera was developed for carrying out mapping for iodine-based contrast media used in medical angiography. Objects are exposed by an X-ray beam from a cerium target. Cerium K-series X-rays are absorbed effectively by iodine media in objects, and iodine fluorescence is produced from the objects. Next, iodine Kalpha fluorescence is selected out by use of a 58-microm-thick stannum filter and is detected by a cadmium telluride (CdTe) detector. The Kalpha rays are discriminated out by a multichannel analyzer, and the number of photons is counted by a counter card. The objects are moved and scanned by an x-y stage in conjunction with a two-stage controller, and X-ray images obtained by iodine mapping are shown on a personal computer monitor. The scan pitch of the x and y axes was 2.5 mm, and the photon counting time per mapping point was 2.0 s. We carried out iodine mapping of non-living animals (phantoms), and iodine Kalpha fluorescence was produced from weakly remaining iodine elements in a rabbit skin cancer.
Matsukiyo
Hiroshi
H
The 3rd Department of Surgery, Toho University School of Medicine, Tokyo, Japan. hma2kiyo502leo@yahoo.co.jp
Watanabe
Manabu
M
Sato
Eiichi
E
Osawa
Akihiro
A
Enomoto
Toshiyuki
T
Nagao
Jiro
J
Abderyim
Purkhet
P
Aizawa
Katsuo
K
Tanaka
Etsuro
E
Mori
Hidezo
H
Kawai
Toshiaki
T
Ehara
Shigeru
S
Sato
Shigehiro
S
Ogawa
Akira
A
Onagawa
Jun
J
D000818:Animals; D019187:Cadmium Compounds; D003287:Contrast Media; D005898:Glass; D006321:Heart; D007455:Iodine; D019047:Phantoms, Imaging; D011817:Rabbits; D012878:Skin Neoplasms; D013052:Spectrometry, X-Ray Emission / Q000379:methods*; D013691:Tellurium
D019187:Cadmium Compounds; D003287:Contrast Media; D007455:Iodine; D013691:Tellurium; C028337:cadmium telluride
Pediatr Radiol. 2001 Aug;31(8):589-93
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Radiology. 2003 Oct;229(1):200-8
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Med Phys. 2004 Nov;31(11):3017-21
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