title: Naringin and vitamin E influence the oxidative stability and lipid profile of plasma in lambs fed fish oil.
abstract: Thirty two Merino lambs (15 weeks old) fed barley straw and fish oil enriched concentrate were used to assess the effect of vitamin E (6 g kg(-1) DM) and naringin (1.5-3 g kg(-1) DM) on plasma lipid peroxidation (TBARS), total antioxidant status (TAS), immune response, plasma cholesterol, and triglycerides. After 21 days feeding the experimental diets, lambs were subjected to a 4 h transportation stress period and then held 4 more hours without feed. TBARS values before stress were lower for animals consuming vitamine E and naringin when compared to control lambs (P<0.05). However, after stress all groups presented similar levels of TBARS. TAS decreased (P<0.05) in all groups in response to stress with values recovering (P<0.05) to pre-stress values following 4 h of rest. A rise (P<0.05) in serum concentrations of triacylglycerol following 21 d of fish oil supplementation was dampened in lambs consuming vitamin E or naringin. Both pre-stress TBARS and triacylglycerol-reducing effects of naringin added to fish oil enriched concentrate for fattening lambs are reported.
authors.affiliation: Instituto de Ganadería de Montaña (CSIC-ULE), Finca Marzanas, s/n, E-24346 Grulleros, León, Spain. Electronic address: raul.bodas@eae.csic.es.
authors.forename: R
authors.initials: R
authors.lastname: Bodas
authors.affiliation: Instituto de Ganadería de Montaña (CSIC-ULE), Finca Marzanas, s/n, E-24346 Grulleros, León, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Prieto
authors.affiliation: Instituto de Ganadería de Montaña (CSIC-ULE), Finca Marzanas, s/n, E-24346 Grulleros, León, Spain.
authors.forename: O
authors.initials: O
authors.lastname: López-Campos
authors.affiliation: Instituto de Ganadería de Montaña (CSIC-ULE), Finca Marzanas, s/n, E-24346 Grulleros, León, Spain.
authors.forename: F J
authors.initials: FJ
authors.lastname: Giráldez
authors.affiliation: Instituto de Ganadería de Montaña (CSIC-ULE), Finca Marzanas, s/n, E-24346 Grulleros, León, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Andrés
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena / Q000187:drug effects; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood; D004032:Diet; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule / Q000662:veterinary; D005395:Fish Oils / Q000008:administration & dosage*; D044950:Flavanones / Q000008:administration & dosage / Q000494:pharmacology*; D001467:Hordeum; D055633:Immune System Phenomena / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008055:Lipids / Q000097:blood*; D011897:Random Allocation; D034561:Sheep, Domestic / Q000276:immunology / Q000502:physiology*; D012885:Skinfold Thickness; D013312:Stress, Physiological; D014280:Triglycerides / Q000097:blood; D014810:Vitamin E / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D005395:Fish Oils; D044950:Flavanones; D008055:Lipids; D014280:Triglycerides; D014810:Vitamin E; D002784:Cholesterol; C005274:naringin