Age at onset of multiple sclerosis is correlated to use of combined oral contraceptives and childbirth before diagnosis.
The aim of this study was to evaluate whether age of onset of multiple sclerosis is related to use of combined oral contraceptives and/or timing of childbirth. The results showed that use of combined oral contraceptives and childbirth before the first multiple sclerosis symptom was correlated to a higher mean age at the onset of the disease.
Holmqvist
Per
P
Division of Womens and Childrens Health, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden. per.holmqvist@lvn.se
Hammar
Mats
M
Landtblom
Anne-Marie
AM
Brynhildsen
Jan
J
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D003277:Contraceptives, Oral, Combined / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D036801:Parturition / Q000502:physiology; D011247:Pregnancy; D012042:Registries; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors; D055815:Young Adult
D003277:Contraceptives, Oral, Combined