title: One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes.
abstract: A new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity. This one-pot process combines an enantioselective organocatalytic Michael addition with a highly diastereoselective [3+2]-cycloaddition-fragmentation step.
authors.affiliation: UMR CNRS 6263 iSm2, Aix-Marseille Université, Centre Saint Jérôme, service 531, 13397 Marseille Cedex 20, France.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Raimondi
authors.forename: Grégory
authors.initials: G
authors.lastname: Lettieri
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Dulcère
authors.forename: Damien
authors.initials: D
authors.lastname: Bonne
authors.forename: Jean
authors.initials: J
authors.lastname: Rodriguez