title: Dosimetric verification in inhomogeneous phantom geometries for the XiO radiotherapy treatment planning system with 6-MV photon beams.
abstract: We have developed a practical dose verification method for radiotherapy treatment planning systems by using only a Farmer ionization chamber in inhomogeneous phantoms. In particular, we compared experimental dose verifications of multi-layer phantom geometries and laterally inhomogeneous phantom geometries for homogeneous and inhomogenous dose calculations by using the fast-Fourier-transform convolution, fast-superposition, and superposition in the XiO radiotherapy treatment-planning system. We applied the dose verification method to three kernel-based algorithms in various phantom geometries with water-, lung- and bone-equivalent media of different field sizes. These calculations were then compared with experimental measurements by use of the Farmer ionization chamber. The fast-Fourier-transform convolution algorithm overestimated the dose by about 8% in the lung phantom geometry. The superposition algorithm and the fast-superposition algorithm were both accurate to better than 2% when compared to the measurements even for complex geometries. Our dose verification method was able to clarify the differences and equivalences of the three kernel-based algorithms and measurements with use only of commonly available apparatus. This will be generally useful in commissioning of inhomogeneity-correction algorithms in the clinical practice of treatment planning.
authors.affiliation: National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan. rkohno@east.ncc.go.jp
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kohno
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kitou
authors.forename: Eriko
authors.initials: E
authors.lastname: Hirano
authors.forename: Satoru
authors.initials: S
authors.lastname: Kameoka
authors.forename: Tomonori
authors.initials: T
authors.lastname: Goka
authors.forename: Teiji
authors.initials: T
authors.lastname: Nishio
authors.forename: Tomoko
authors.initials: T
authors.lastname: Miyagishi
authors.forename: Takaki
authors.initials: T
authors.lastname: Ariji
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Kawashima
authors.forename: Takashi
authors.initials: T
authors.lastname: Ogino
mesh_terms: D000465:Algorithms; D006801:Humans; D019047:Phantoms, Imaging; D017785:Photons; D011874:Radiometry / Q000295:instrumentation*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*
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