Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus.
We report on an intravenous drug user who presented with methicillin-sensitive Staphylococcus aureus bacteremia and endocarditis of a prosthetic tricuspid valve, with a 4-cm vegetation refractory to standard antibiotic treatment. The patient responded to intravenous daptomycin therapy clinically and microbiologically, despite an absence of surgical intervention.
Cheung
Ling Ling
LL
Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong. ling-x-2@hotmail.com
Yue
Chiu Sun
CS
Fung
Kitty
K
Chu
Chung Ming
CM
Keung Tso
Eugene Yuk
EY
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017576:Daptomycin / Q000627:therapeutic use*; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D010996:Pleural Effusion / Q000188:drug therapy; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus; D017211:Treatment Failure
D000900:Anti-Bacterial Agents; D017576:Daptomycin