title: Prostatic blue nevus.
abstract: We report the case of a 69-year-old patient with no significant personal urological history. The clinical and ultrasound examination revealed a prostatic gland with increased volume and homogenous appearance. After transurethral resection, multiples gray-brown-blackish prostatic chips were obtained, which could be confused with a malignant melanoma. The histological routine examination in conjunction with the histochemical (Fontana-Masson) and immunohistochemical (S100, HMB45) reactions established the diagnosis of prostatic blue nevus. The presence of melanin in prostatic tissue is an unusual aspect, being encountered three distinct lesions: blue nevus, melanosis and malignant melanoma. Recognition and correct classification of each of these three entities is fundamental, concerning the clinical and prognosis implications.
authors.affiliation: Department of Pathology, Emergency County Hospital, Timisoara, Romania. denisa_dobre@yahoo.com
authors.forename: Denisa
authors.initials: D
authors.lastname: Anderco
authors.forename: Elena
authors.initials: E
authors.lastname: Lazăr
authors.forename: Sorina
authors.initials: S
authors.lastname: Tăban
authors.forename: Fl
authors.initials: F
authors.lastname: Miclea
authors.forename: Alis
authors.initials: A
authors.lastname: Dema
mesh_terms: D000368:Aged; D003713:Dendritic Cells / Q000473:pathology; D006801:Humans; D008297:Male; D018329:Nevus, Blue / Q000473:pathology*; D011467:Prostate / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology
chemical_list: D009418:S100 Proteins