title: Interferon-gamma-release assays: Better than tuberculin skin testing?
abstract: Although the tuberculin skin test has long been the standard for detecting latent tuberculosis infection, it has many limitations. Interferon-gamma-release assays are gaining acceptance as an alternative. In this paper we present cases to illustrate how these new tests can be used and how to interpret the results.
authors.affiliation: Department of Infectious Disease, Medicine Institute, G21, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. mirandc@ccf.org
authors.forename: Cyndee
authors.initials: C
authors.lastname: Miranda
authors.forename: J Walton
authors.initials: JW
authors.lastname: Tomford
authors.forename: Steven M
authors.initials: SM
authors.lastname: Gordon
mesh_terms: D000328:Adult; D000368:Aged; D001769:Blood / Q000276:immunology; D001773:Blood Cells / Q000276:immunology; D002478:Cells, Cultured / Q000276:immunology; D005260:Female; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D007371:Interferon-gamma / Q000032:analysis* / Q000096:biosynthesis*; D055985:Latent Tuberculosis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000276:immunology*
chemical_list: D007371:Interferon-gamma