title: [Amyloidosis and end-stage renal disease associated with leprosy].
abstract: Renal involvement in leprosy includes glomerulonephritis, amyloidosis and tubulointerstitial nephritis. A 58-year-old man was admitted with complaints of lower limb edema and dyspnea. At admission, nitrogen retention, anemia, hyperkalemia and metabolic acidosis were observed, requiring hemodialysis. The patient had a history of lepromatous leprosy. A renal biopsy was performed that was compatible with amyloidosis. The patient had a stable outcome, but without renal function recovery and remained on regular hemodialysis. Leprosy should be investigated in every patient with renal function loss, particularly in those with cutaneous lesions or other manifestations suggestive of leprosy.
authors.affiliation: Departamento de Medicina Clínica, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE.
authors.forename: Geraldo Bezerra da
authors.initials: GB
authors.lastname: Silva Júnior
authors.forename: Orivaldo Alves
authors.initials: OA
authors.lastname: Barbosa
authors.forename: Roseanne de Moura
authors.initials: Rde M
authors.lastname: Barros
authors.forename: Priscila Dos Reis
authors.initials: Pdos R
authors.lastname: Carvalho
authors.forename: Talita Rodrigues de
authors.initials: TR
authors.lastname: Mendoza
authors.forename: Dulce Maria Sousa
authors.initials: DM
authors.lastname: Barreto
authors.forename: Célio Araújo
authors.initials: CA
authors.lastname: Barboza
authors.forename: Antônio Augusto Carvalho
authors.initials: AA
authors.lastname: Guimarães
authors.forename: Elizabeth de Francesco
authors.initials: Ede F
authors.lastname: Daher
mesh_terms: D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000628:therapy; D007918:Leprosy / Q000150:complications*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods