Lupus cystitis in an Omani girl.
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organs involvement. Bladder involvement (Lupus cystitis) is a rare manifestation of SLE, and occurs in association with gastrointestinal manifestations. We report a case of lupus interstitial cystitis with bladder irritation and bilateral hydroureteronephrosis in an adolescent female who was treated with intravenous methylprednisolone pulse therapy followed by oral prednisolone and mycofenolate mofetil (MMF). Her symptoms ameliorated, and the hydroureteronephrosis improved. She was presented again with systemic flare up of the disease together with hydrouretronephrosis, but without bladder irritation symptoms. The diagnosis of lupus cystitis was confirmed by radiographic abnormalities, cystoscopy and bladder biopsy.
Al-Shibli
Amar
A
Department of Pediatrics, Tawam Hospital, Al Ain, Saudi Arabia.
Al-Salam
Suhail
S
Bernieh
Bassam
B
Matta
Hilal
H
Al Attrach
Ibrahim
I
D000284:Administration, Oral; D000293:Adolescent; D001706:Biopsy; D003556:Cystitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003558:Cystoscopy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008775:Methylprednisolone / Q000008:administration & dosage; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D009850:Oman; D011239:Prednisolone / Q000008:administration & dosage; D020551:Pulse Therapy, Drug; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color
D007166:Immunosuppressive Agents; D011239:Prednisolone; D009173:Mycophenolic Acid; D008775:Methylprednisolone