title: Preoperative exchange transfusion for sickle cell disease patients undergoing open-heart surgery: an exception to the rule.
abstract: Preoperative exchange transfusion is a routine practice in patients with sickle cell disease having elevated sickle cell hemoglobin levels (>40%) undergoing open-heart surgery on cardiopulmonary bypass. A new approach toward acceptance and management of sickle cell disease patients with high sickle cell hemoglobin levels for open-heart surgery without preoperative exchange transfusion of blood is presented.
authors.affiliation: Royal Hospital, Muscat, Sultanate of Oman.
authors.forename: Ravindra K
authors.initials: RK
authors.lastname: Adhikari
authors.forename: Madan M
authors.initials: MM
authors.lastname: Maddali
authors.forename: Sunny
authors.initials: S
authors.lastname: Zacharias
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications*; D006348:Cardiac Surgical Procedures; D002648:Child; D004573:Electrolytes / Q000097:blood; D005078:Exchange Transfusion, Whole Blood; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000601:surgery*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D019990:Perioperative Care; D016896:Treatment Outcome
chemical_list: D004573:Electrolytes; D006454:Hemoglobins