title: [Differences in fraction of exhaled nitric oxide values measured by two offline methods or NIOXmino in adult Japanese asthmatics].
abstract: BACKGROUND
  The fraction of exhaled nitric oxide (FeNO) is a useful marker of asthma control. The FeNO measurement with two offline methods and NIOXmino may be more affordable, no studies have examined the differences in FeNO values measured with various methods in adult asthmatics.
  
  
  METHODS
  The study population comprised 39 stable asthmatics treated with inhaled steroids at our outpatient clinic. FeNO values were measured by two offline methods (Sievers and CEIS), NIOXmino.
  
  
  RESULTS
  FeNO(NIOXmino) values were significantly correlated with those of FeNO(Sievers) (r=0.935, P< 0.001) and FeNOCEIS (r=0.908, P< 0.001). However, FeNO(NIOXmino) values were low compared with FeNO(Sievers) (FeNO(NIOXmino)=0.848 x FeNO(Sievers)) and FeNO(CEIS) (FeNO(NIOXmino)=0.672 x FeNO(CEIS)).
  
  
  CONCLUSIONS
  Differences exist in the values of FeNO measured by various methods: conversion equations are needed to compare the FeNO values among these three methods.
authors.affiliation: Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuburai
authors.forename: Naomi
authors.initials: N
authors.lastname: Tsurikisawa
authors.forename: Noritaka
authors.initials: N
authors.lastname: Higashi
authors.forename: Sayaka
authors.initials: S
authors.lastname: Tatsuno
authors.forename: Yuma
authors.initials: Y
authors.lastname: Fukutomi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Tanimoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Sekiya
authors.forename: Chiyako
authors.initials: C
authors.lastname: Oshikata
authors.forename: Mamoru
authors.initials: M
authors.lastname: Otomo
authors.forename: Yuji
authors.initials: Y
authors.lastname: Maeda
authors.forename: Masami
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Ikehara
authors.forename: Kazuo
authors.initials: K
authors.lastname: Akiyama
mesh_terms: D001249:Asthma / Q000503:physiopathology*; D001944:Breath Tests / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000032:analysis*
chemical_list: D009569:Nitric Oxide