title: Sleep-disordered breathing in Vietnam veterans with posttraumatic stress disorder.
abstract: OBJECTIVE
  : To study the prevalence of sleep-disordered breathing (SDB) in Vietnam- era veterans.
  
  
  METHODS
  : This was an observational study of Vietnam-era veterans using unattended, overnight polysomnography, cognitive testing, and genetic measures.
  
  
  RESULTS
  : A sample of 105 Vietnam-era veterans with posttraumatic stress disorder: 69% had an Apnea Hypopnea Index >10. Their mean body mass index was 31, "obese" by Centers for Disease Control and Prevention criteria, and body mass index was significantly associated with Apnea Hypopnea Index (Spearman r = 0.41, N = 97, p < 0.0001). No significant effects of sleep-disordered breathing or apolipoprotein status were found on an extensive battery of cognitive tests.
  
  
  CONCLUSIONS
  : There is a relatively high prevalence of SDB in these patients which raises the question of to what degree excess cognitive loss in older PTSD patients may be due to a high prevalence of SDB.
authors.affiliation: Department of Veterans Affairs Health Care System, Palo Alto, CA 94304, USA. yesavage@stanford.edu
authors.forename: Jerome A
authors.initials: JA
authors.lastname: Yesavage
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Kinoshita
authors.forename: Timothy
authors.initials: T
authors.lastname: Kimball
authors.forename: Jamie
authors.initials: J
authors.lastname: Zeitzer
authors.forename: Leah
authors.initials: L
authors.lastname: Friedman
authors.forename: Art
authors.initials: A
authors.lastname: Noda
authors.forename: Renaud
authors.initials: R
authors.lastname: David
authors.forename: Beatriz
authors.initials: B
authors.lastname: Hernandez
authors.forename: Tina
authors.initials: T
authors.lastname: Lee
authors.forename: Jauhtai
authors.initials: J
authors.lastname: Cheng
authors.forename: Ruth
authors.initials: R
authors.lastname: Oʼhara
mesh_terms: D001057:Apolipoproteins E / Q000235:genetics; D015992:Body Mass Index; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D017286:Polysomnography; D015995:Prevalence; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000453:epidemiology* / Q000523:psychology; D013313:Stress Disorders, Post-Traumatic / Q000150:complications*; D014728:Veterans / Q000523:psychology* / Q000706:statistics & numerical data; D047829:Vietnam Conflict
chemical_list: D001057:Apolipoproteins E