title: [Digital ulcers in systemic sclerosis--an interdisciplinary challenge].
abstract: Digital ulcers in systemic sclerosis are painful ischemic necrotic lesions of the acra. Optimal treatment consists of conventional wound management and medication: iloprost infusions promote primary healing of the ulcers, while the dual endothelin receptor antagonist bosentan is used for secondary prophylaxis of new ulcers. The described case illustrates the essential interdisciplinary collaboration for optimal management of these patients.
authors.affiliation: III. Medizinische Klinik, Funktionsbereich Rheumatologie/Osteologie, Zentralklinikum Augsburg, Augsburg, Germany. fwiesent@hotmail.de
authors.forename: Franziska
authors.initials: F
authors.lastname: Wiesent
authors.forename: Jutta
authors.initials: J
authors.lastname: Weinerth
mesh_terms: D000792:Angiography; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001132:Arm / Q000098:blood supply; D000077300:Bosentan; D017675:CREST Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D003299:Cooperative Behavior; D065128:Endothelin Receptor Antagonists; D017809:Fatal Outcome; D005385:Fingers; D005500:Follow-Up Studies; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use; D033183:Interdisciplinary Communication; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D045745:Scleroderma, Limited / Q000175:diagnosis* / Q000188:drug therapy; D012883:Skin Ulcer / Q000175:diagnosis* / Q000188:drug therapy; D013449:Sulfonamides / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000959:Antihypertensive Agents; D065128:Endothelin Receptor Antagonists; D013449:Sulfonamides; D014665:Vasodilator Agents; D016285:Iloprost; D000077300:Bosentan
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