(106)Ruthenium brachytherapy for ciliary recurrence with supraciliary effusion in retinoblastoma.
OBJECTIVE
A 2-year-old boy with syndromic bilateral retinoblastoma resulting from a (del(13)(q12.3q14.3)) developed a recurrent tumor measuring 2.3 X 2.3 mm at the ora serrata 15 months following last treatment.


METHODS
Ultrasound biomicroscopy (UBM) revealed a mass invading the ciliary body 6.6 mm in diameter associated with a localized supraciliary effusion.


RESULTS
Complete tumor regression was achieved 1 month after brachytherapy with a (106)Ruthenium plaque. There was no recurrence at 16 months.


CONCLUSIONS
This is the first clinical demonstration of supraciliary effusion in recurrent retinoblastoma. Brachytherapy appears to be effective in the treatment of this type of recurrence.
Chhablani
Jay
J
Vitreo-Retina Services, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
Romanzo
Antonio
A
Balmer
Aubin
A
Pica
Alessia
A
Gaillard
Marie-Claire
MC
Cozza
Raffaele
R
Moeckli
Raphaël
R
Munier
Francis L
FL
D001918:Brachytherapy; D002675:Child, Preschool; D002872:Chromosome Deletion; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics; D002924:Ciliary Body / Q000000981:diagnostic imaging / Q000473:pathology / Q000528:radiation effects*; D006801:Humans; D008297:Male; D033401:Microscopy, Acoustic; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000532:radiotherapy*; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000235:genetics / Q000532:radiotherapy*; D012429:Ruthenium Radioisotopes / Q000627:therapeutic use*; D014604:Uveal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*
D012429:Ruthenium Radioisotopes