[Etiology of colorectal cancer and antioxidant barrier of the organism].
Colorectal cancer is a serious medical and economic problem in Poland, as the detection and results of its treatment are very low. Due to this fact, medical research is still conducted in order to find out the symptoms of this tumor and proper preventive measures. According to one hypothesis of carcinogenesis, the process of creating the tumor begins and develops when the balance between the production of reactive oxygen species (ROS) and their deactivation by the "antioxidant protective barrier of the organism" is disturbed. As a result of this theory, it has been decided to examine the plasma concentration of the dietary minerals which work as antioxidants. The results entailed conclusions which prove the free radicals theory of carcinogenesis. They also confirm the part which the antioxidant protective barrier plays in the defence against ROS and their carcinogenic consequences.
Klimczak
Alicja
A
Uniwersytet Medyczny w Łodzi, Wydział Fizjoterapii, III Katedra Rehabilitacji, Zakład Historii Nauk i Medycyny Wojskowej. ala_klimczak@o2.pl
Kubiak
Katarzyna
K
Cybulska
Magdalena
M
Kula
Agnieszka
A
Dziki
Łukasz
Ł
Malinowska
Katarzyna
K
D000975:Antioxidants / Q000378:metabolism*; D003111:Colonic Polyps / Q000175:diagnosis / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D011230:Precancerous Conditions / Q000175:diagnosis / Q000378:metabolism; D012307:Risk Factors
D000975:Antioxidants; D005609:Free Radicals