Sensory input pathways and mechanisms in swallowing: a review.
Over the past 20 years, research on the physiology of swallowing has confirmed that the oropharyngeal swallowing process can be modulated, both volitionally and in response to different sensory stimuli. In this review we identify what is known regarding the sensory pathways and mechanisms that are now thought to influence swallowing motor control and evoke its response. By synthesizing the current state of research evidence and knowledge, we identify continuing gaps in our knowledge of these mechanisms and pose questions for future research.
Steele
Catriona M
CM
Toronto Rehabilitation Institute, 550 University Avenue, #12030, Toronto, ON, M5G 2A2, Canada. steele.catriona@torontorehab.on.ca
Miller
Arthur J
AJ
D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000473:pathology; D004947:Esophagus / Q000033:anatomy & histology / Q000473:pathology / Q000502:physiology; D006801:Humans; D009044:Motor Cortex / Q000502:physiology*; D009833:Olfactory Pathways / Q000502:physiology*; D010614:Pharynx / Q000033:anatomy & histology / Q000473:pathology / Q000502:physiology; D010775:Photic Stimulation; D012472:Salivation; D012677:Sensation / Q000502:physiology*; D012903:Smell / Q000502:physiology
Am J Physiol. 1990 May;258(5 Pt 1):G675-81
2333995
Brain Res. 1987 Apr 7;408(1-2):173-84
3297247
Dysphagia. 1996 Winter;11(1):2-8
8556873
J Speech Lang Hear Res. 2007 Jun;50(3):585-94
17538102
Ann Otol Rhinol Laryngol. 2005 Mar;114(3):223-8
15825573
Nat Neurosci. 1998 May;1(1):64-8
10195111
J Neurophysiol. 1992 Jun;67(6):1659-68
1629769
Am J Med. 2000 Mar 6;108 Suppl 4a:62S-67S
10718454
Pflugers Arch Gesamte Physiol Menschen Tiere. 1964;278:467-77
14126442
J Neurophysiol. 2004 Oct;92(4):2428-43
15163677
Gastroenterology. 1974 Aug;67(2):245-51
4847704
Am J Physiol. 1951 Jul;166(1):142-58
14857157
Neurosci Lett. 2008 Dec 19;448(1):139-42
18930115
Brain Res. 1972 Nov 13;46:43-54
4635374
Brain Res. 1979 Dec 14;178(2-3):567-72
509218
Behav Brain Res. 2009 Oct 12;203(1):118-26
19409935
Sens Processes. 1979 Mar;3(1):1-26
229568
Am J Physiol Gastrointest Liver Physiol. 2001 Nov;281(5):G1246-63
11668034
Am J Physiol Regul Integr Comp Physiol. 2002 May;282(5):R1342-7
11959674
Physiol Behav. 2007 May 16;91(1):66-70
17350055
Gerontology. 2003 Jan-Feb;49(1):12-20
12457045
J Neurophysiol. 1992 Oct;68(4):1053-67
1432067
J Neurophysiol. 1990 Sep;64(3):796-812
2230925
Dysphagia. 2005 Fall;20(4):254-60
16633868
Gastroenterol Clin North Am. 2002 Dec;31(4 Suppl):S21-33
12489468
Gastroenterology. 1993 Jan;104(1):152-62
8419238
J Neurophysiol. 1956 Jan;19(1):44-60
13286721
Am J Gastroenterol. 1999 Jun;94(6):1457-63
10364007
Science. 1973 Mar 9;179(4077):1016-7
4687587
J Neurophysiol. 1999 Apr;81(4):1917-26
10200226
Am J Physiol. 1996 Feb;270(2 Pt 1):G347-54
8779978
Dysphagia. 2004 Winter;19(1):1-6
14745639
Am J Physiol. 1998 Sep;275(3):G521-5
9724264
Ann Otol Rhinol Laryngol. 2005 Mar;114(3):173-6
15825564
Neuroscience. 2005;135(4):1285-94
16165290
Acta Radiol. 2003 Jul;44(4):366-72
12846685
Am J Physiol Gastrointest Liver Physiol. 2000 Aug;279(2):G255-61
10915632
Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G242-7
12388187
Brain Res. 1969 Sep;15(1):107-20
5807759
Exp Neurol. 1968 Mar;20(3):366-83
5656850
Gastroenterology. 1976 Dec;71(6):1004-9
825409
Am J Physiol. 1997 Feb;272(2 Pt 1):G265-71
9124350
Clin Chest Med. 1986 Jun;7(2):211-22
3522068
Dysphagia. 1995 Fall;10(4):235-47
7493504
J Neurophysiol. 1964 May;27:464-80
14170133
J Am Geriatr Soc. 2006 Sep;54(9):1401-6
16970649
Gastroenterology. 2004 Jul;127(1):57-64
15236172
Laryngoscope. 1974 Mar;84(3):427-37
4814413
Respir Physiol. 1995 Jul;101(1):31-9
8525119
J Oral Rehabil. 2009 Dec;36(12):872-9
19840359
Dysphagia. 2001 Summer;16(3):176-82
11453563
Dysphagia. 2006 Apr;21(2):121-8
16703444
J Neurophysiol. 2001 Feb;85(2):938-50
11160524
Brain Res. 1990 Jan 29;508(1):168-71
2337785
Hum Brain Mapp. 2009 Jan;30(1):92-100
17979116
Dysphagia. 1993;8(3):259-65
8359048
Jpn J Physiol. 1976;26(5):455-69
1011388
Dysphagia. 1996 Fall;11(4):225-33
8870348
Anat Rec. 2000 Apr 1;258(4):406-20
10737859
Clin Neurophysiol. 2004 Oct;115(10):2382-90
15351381
Ann Otol Rhinol Laryngol. 1994 Oct;103(10):749-52
7944164
Am J Med. 2000 Mar 6;108 Suppl 4a:68S-72S
10718455
Neural Plast. 2001;8(1-2):91-7
11530891
J Neurophysiol. 1995 Jun;73(6):2144-62
7666129
Dysphagia. 2008 Dec;23(4):392-405
18855050
Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G137-44
12606304
Laryngoscope. 1999 Mar;109(3):437-41
10089972
Arch Phys Med Rehabil. 1993 Oct;74(10):1066-70
8215858
Brain Res. 1989 Feb 20;480(1-2):133-50
2713648
Gastroenterology. 1978 Apr;74(4):801-3
415932
Dysphagia. 2003 Winter;18(1):16-26
12497192
Dysphagia. 2002 Fall;17(4):278-87
12355143
Gut. 2002 Dec;51(6):771-5
12427774
Am J Med. 2000 Mar 6;108 Suppl 4a:79S-86S
10718457
Am J Physiol. 1994 Oct;267(4 Pt 1):G644-9
7943330
Percept Mot Skills. 2002 Jun;94(3 Pt 1):1029-40
12081263
Gastroenterology. 1973 Nov;65(5):750-6
4758972
Lancet. 1997 Sep 6;350(9079):686-92
9291902
Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R651-6
16601262
J Physiol. 2003 Jul 1;550(Pt 1):287-304
12754311
Dysphagia. 1992;7(4):187-200
1308667
Dysphagia. 1998 Winter;13(1):1-9
9391220
Jpn J Physiol. 1977;27(1):27-42
864868
J Neurophysiol. 2000 Mar;83(3):1264-72
10712454
J Comp Neurol. 1956 Sep;105(2):269-85
13385376
Am J Anat. 1972 Mar;133(3):333-40
5026658
Neurogastroenterol Motil. 2003 Jun;15(3):323-9
12787342
Dysphagia. 2009 Jun;24(2):218-29
19130130
Dysphagia. 2009 Sep;24(3):302-13
19390893
Braz J Med Biol Res. 1990;23(1):37-44
2386847
Eur Arch Otorhinolaryngol. 2001 Jan;258(1):49-53
11271436
Physiol Rev. 1975 Jul;55(3):352-82
1098067
J Speech Lang Hear Res. 2009 Oct;52(5):1255-67
19797138
Exp Neurol. 1967 Jan;17(1):91-106
4959819
Exp Neurol. 1975 Apr;47(1):42-55
1123009
Am J Speech Lang Pathol. 2007 May;16(2):140-7
17456892
Ann Otol Rhinol Laryngol. 1993 Oct;102(10):777-80
8215097
Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G44-53
11408254
Exp Neurol. 1974 Feb;42(2):369-87
4824983
J Auton Nerv Syst. 1983 Feb;7(2):87-96
6875188
Exp Brain Res. 1990;81(2):384-90
1697811
Brain Res. 1988 Jan 26;439(1-2):195-210
3359184
Gut. 1998 Oct;43(4):537-41
9824582
J Neurophysiol. 1993 Sep;70(3):1168-80
8229166
Arch Oral Biol. 1973 Aug;18(8):971-80
4517320
Gastroenterology. 1995 May;108(5):1418-26
7729634
Respir Med. 1991 Jan;85 Suppl A:57-60
2034837
Exp Brain Res. 1984;55(1):105-10
6745343
J Speech Hear Res. 1991 Dec;34(6):1257-68
1787707
Arch Oral Biol. 1995 Jun;40(6):507-12
7677595
J Acoust Soc Am. 2001 Jul;110(1):368-79
11508961
Prog Neurobiol. 1979;12(1):15-32
394188
Exp Neurol. 1972 Feb;34(2):210-22
5016195
Neurogastroenterol Motil. 2003 Feb;15(1):69-77
12588471
J Speech Hear Res. 1995 Jun;38(3):556-63
7674647
Brain Res Bull. 1989 May;22(5):883-91
2765947
Am J Physiol. 1970 Apr;218(4):956-60
5435428
J Speech Lang Hear Res. 2004 Feb;47(1):33-45
15072526
J Comp Neurol. 1986 Mar 22;245(4):471-82
3700710
J Physiol (Paris). 1970;62 Suppl 1:170
5432428
Neuroimage. 2008 Aug 1;42(1):285-95
18515150
Neuroscience. 2007 Mar 30;145(3):791-4
17320301
Dysphagia. 1993;8(3):195-202
8359039
Exp Brain Res. 1995;105(2):241-53
7498377
Am J Physiol. 1971 Nov;221(5):1260-3
5124270
Ann Otol Rhinol Laryngol. 2002 Apr;111(4):291-4
11991578
Am J Physiol. 1997 Nov;273(5):G1071-6
9374704
Acta Otolaryngol. 1975 May-Jun;79(5-6):445-50
1155054
J Neurophysiol. 1989 May;61(5):1001-10
2723726
Neurosci Lett. 1992 Nov 9;146(2):155-8
1491782
Am J Med. 2001 Dec 3;111 Suppl 8A:169S-173S
11749945
Dysphagia. 1993;8(2):146-9
8467722
Exp Neurol. 1968 Mar;20(3):359-65
5656849
Dysphagia. 1996 Summer;11(3):198-206
8755466
Clin Sci (Lond). 2000 Aug;99(2):151-7
10918049
Am J Physiol. 1997 Apr;272(4 Pt 1):G802-8
9142911
Respir Physiol. 1988 Mar;71(3):287-97
3375602
Clin Neurophysiol. 2004 May;115(5):1044-51
15066528
Physiol Behav. 2002 Nov;77(2-3):321-5
12419408
Sleep Med Rev. 2010 Oct;14(5):299-305
20116305
Dysphagia. 1994 Summer;9(3):149-55
8082322
Jpn J Physiol. 1972 Jun;22(3):295-314
4539752
Dysphagia. 2003 Fall;18(4):231-41
14571326
Am J Physiol. 1999 Jul;277(1):G219-25
10409170
Dysphagia. 1998 Spring;13(2):87-92
9513302