Ionic liquid under ultrasonic irradiation towards a facile synthesis of pyrazolone derivatives.
Ionic liquid [HMIM]HSO(4) was found to be an efficient catalyst for the synthesis of 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-phenyl-methyl]-5-methyl-2-phen-yl-1,2-dihydro-pyrazol-3-ones through the condensation reaction of arylaldehydes and 3-methyl-1-phenyl-5-pyrazolone under ultrasonic irradiation at room temperature. The present methodology offers several advantages such as excellent yields, simple procedure and mild conditions.
Zang
Hongjun
H
Department of Environmental and Chemistry Engineering, Tianjin Polytechnic University, State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Tianjin 300160, China. zanghongjun@tjpu.edu.cn
Su
Qiuhong
Q
Mo
Yingming
Y
Cheng
Bowen
B
D018360:Crystallography, X-Ray; D052578:Ionic Liquids / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D047069:Pyrazolones / Q000138:chemical synthesis* / Q000737:chemistry; D014465:Ultrasonics
D052578:Ionic Liquids; D047069:Pyrazolones; C038362:pyrazolone