title: Linear childhood discoid lupus erythematosus following the lines of Blaschko: successfully treated with topical tacrolimus.
abstract: The linear arrangement of discoid lupus erythematosus is uncommon. Here, we report a 6-year-old Japanese girl with linear discoid lupus erythematosus following the lines of Blaschko on her face and neck. Topical tacrolimus treatment improved the eruptions. The present case also indicated the important role of epidermal and dermal cells as well as immune cells in the pathogenesis of cutaneous lupus erythematodes.
authors.affiliation: Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan. hukyasuhir@md.tsukuba.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kawachi
authors.forename: Shijima
authors.initials: S
authors.lastname: Taguchi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujisawa
authors.forename: Junichi
authors.initials: J
authors.lastname: Furuta
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ishii
authors.forename: Fujio
authors.initials: F
authors.lastname: Otsuka
mesh_terms: D000287:Administration, Topical; D001706:Biopsy; D002648:Child; D005145:Face / Q000473:pathology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy* / Q000473:pathology*; D016559:Tacrolimus / Q000008:administration & dosage*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus