title: High rates of advanced gastric cancer in community of Flushing, New York.
abstract: BACKGROUND
  Gastric cancer remains a major public health issue and is a leading cause of death worldwide, accounting for 600,000 deaths annually. Over the last decades, there has been a steady decline in the incidence rates of gastric cancer. Furthermore, the incidence rates of gastric cancer in different parts of the country vary due to epidemiological and migration trends. Despite these trends, several studies that have continued to observe high rates of gastric cancer in populations that come from high-risk regions.
  
  
  OBJECTIVE
  The aim of the study was to describe the gastric cancer patients presenting NYHQ with an emphasis on those presenting at a young age and advanced disease. A subanalysis of the Asian population was also done, which is considered a high-risk group.
  
  
  METHODS
  Consecutive chart review of patients admitted with gastric cancer from January 2000 to August 2008 was extracted from the Oncology registry at NYHQ. Parameters that were evaluated were age, sex, race, type of gastric cancer, and stage of gastric cancer at initial presentation. The SAS/PC software package (SAS Institute Inc., Cary, NC) was employed for statistical analyses.
  
  
  RESULTS
  Four hundred fifty-seven patients were diagnosed with gastric cancer. Approximately one third of the total patients were younger than 60 years of age. Of the Asian patients, almost half the patients (48.8%) had advanced disease of which two thirds were under the age of 60 years.
  
  
  CONCLUSIONS
  The rates of advanced gastric cancer observed at NYHQ are significant and comparable to recent epidemiology literature on rates in Asian populations in Asia. Communities, like Flushing, NY, may benefit from early detection of gastric cancers, similar to those instituted in Japan and Taiwan.
authors.affiliation: Department of Medicine, New York Hospital Queens, New York, NY, USA. amreen.dinani@gmail.com
authors.forename: Amreen
authors.initials: A
authors.lastname: Dinani
authors.forename: Amit
authors.initials: A
authors.lastname: Desai
authors.forename: Nina
authors.initials: N
authors.lastname: Kohn
authors.forename: Ellen
authors.initials: E
authors.lastname: Gutkin
authors.forename: Michel
authors.initials: M
authors.lastname: Nussbaum
authors.forename: Kaumudi
authors.initials: K
authors.lastname: Somnay
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000208:ethnology / Q000401:mortality; D013997:Time Factors
references.citation: JAMA. 2010 May 5;303(17):1723-8
references.pmid: 20442388
references.citation: Int J Cancer. 1999 Sep 24;83(1):18-29
references.pmid: 10449602
references.citation: Cancer Causes Control. 1999 Feb;10(1):77-83
references.pmid: 10334646
references.citation: Cancer. 2000 Nov 1;89(9):1883-92
references.pmid: 11064344
references.citation: Eur J Cancer. 1996 May;32A(5):761-71
references.pmid: 9081351
references.citation: Cancer Control. 2007 Jan;14(1):78-85
references.pmid: 17242674
references.citation: Eur J Cancer Prev. 1999 Jul;8(3):223-7
references.pmid: 10443951
references.citation: CA Cancer J Clin. 2007 Jul-Aug;57(4):190-205
references.pmid: 17626117
references.citation: Cancer Causes Control. 2007 Aug;18(6):585-93
references.pmid: 17406989
references.citation: J Gastrointest Surg. 2004 Mar-Apr;8(3):240-4
references.pmid: 15019915
references.citation: South Med J. 1993 Mar;86(3):302-4
references.pmid: 8451669
references.citation: Cancer Epidemiol Biomarkers Prev. 1994 Jan-Feb;3(1):15-8
references.pmid: 8118379
references.citation: Recent Results Cancer Res. 1998;154:298-305
references.pmid: 10027010
references.citation: Cancer Causes Control. 1998 Jan;9(1):1-2
references.pmid: 9486457
references.citation: Semin Oncol. 2004 Aug;31(4):450-64
references.pmid: 15297938
references.citation: Semin Radiat Oncol. 2002 Apr;12(2):111-27
references.pmid: 11979413
references.citation: Ann Oncol. 2010 Jan;21(1):152-60
references.pmid: 19622590
references.citation: Br J Surg. 1985 Apr;72(4):289-91
references.pmid: 3986480
references.citation: Cancer. 1972 May;29(5):1261-3
references.pmid: 4336630
references.citation: N Engl J Med. 2000 Jul 13;343(2):78-85
references.pmid: 10891514
references.citation: West J Med. 1991 Feb;154(2):172-4
references.pmid: 2006563
references.citation: Clin Gastroenterol Hepatol. 2006 Jun;4(6):709-16
references.pmid: 16765306
references.citation: Cancer. 1992 Jul 1;70(1):50-5
references.pmid: 1606546
references.citation: World J Gastroenterol. 2006 Jan 21;12(3):354-62
references.pmid: 16489633
references.citation: Lancet. 1997 May 24;349(9064):1498-504
references.pmid: 9167458