title: Urinary bladder diverticulum and its association with malignancy: an anatomical study on cadavers.
abstract: Present work was directed to study the prevalence and anatomical basis of diverticulum formation and its association with malignancy inside the urinary bladder on cadavers. Urinary bladder diverticulum and its complications including malignancy has been reported by different authors based on their study on radiological findings and endoscopy. Present study was undertaken on cadavers to meet the aforementioned objectives. Thirty properly embalmed cadavers (19 males and 11 females) of different ages were dissected. Sagittal section of pelvis was studied. Urinary bladder was incised to expose the interior and it was examined for the presence of diverticulum (including number and location). Detailed history of the cause of death of cadavers with diverticulum was studied to determine how many of them suffered from urinary bladder diverticular carcinoma. 23.4% cadavers (31.6% males and 9.1% females) showed presence of urinary bladder diverticulum. The location of the diverticulum in all the cadavers was on superior and lateral side of the ureteric opening on the posterior surface of the urinary bladder. Diverticulum of one male cadaver aged 74 years was complicated by malignancy. Our study observed greater prevalence of diverticulum formation as compared to previous reports. In the present work, 14.3% diverticulum of the urinary bladder showed malignant change, which is more than earlier reports in the literature. Urinary bladder diverticulum should neither be neglected nor ignored. Appropriate early treatment (including the cause) of the diverticulum should be undertaken to avoid complications like malignancy which will finally ensure longevity.
authors.affiliation: Department of Anatomy, Vydehi Institute of Medical Sciences and Research Centre, Whitefield, Bangalore, Karnataka, India. prakashrinku@rediffmail.com
authors.lastname: Prakash
authors.forename: T
authors.initials: T
authors.lastname: Rajini
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar Bhardwaj
authors.forename: Jayanthi
authors.initials: J
authors.lastname: V
authors.forename: P
authors.initials: P
authors.lastname: Kalyani Rao
authors.forename: Gajendra
authors.initials: G
authors.lastname: Singh
mesh_terms: D000328:Adult; D000368:Aged; D002102:Cadaver; D004240:Diverticulum / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D001745:Urinary Bladder Diseases / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*