Catalytically-promoted analyte derivatization inside a gas chromatographic inlet.
Reported here is a preliminary assessment of the feasibility of catalyzing on-line derivatization reactions inside the inlet (i.e., the injection port) of a gas chromatograph (GC) with solid heterogeneous catalysts. The experiments described here entail the installation of candidate catalysts inside the GC inlet liner and the subsequent injection of analyte/reagent mixtures onto the catalyst beds. Two catalysts are identified, each of which clearly catalyzes one of the chosen model derivatization reactions in the inlet of a GC. This result supports our hypothesis that on-line derivatizations can, in principle, be reproducibly catalyzed inside the GC inlet by solid heterogeneous catalysts and that the presence of such catalysts in the inlet do not necessarily cause a serious loss of instrument performance or chromatographic efficiency.
Fowler
William K
WK
OI Analytical/CMS Field Products, 2148 Pelham Parkway, Building 400, Pelham, AL 35124, USA. bfowler@oioc.com
Gamble
Kelly J
KJ
Wright
Amber R
AR
D000081:Acetamides; D002384:Catalysis; D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods; D005463:Fluoroacetates; D007287:Inorganic Chemicals / Q000737:chemistry; D009930:Organic Chemicals / Q000737:chemistry; D014269:Trifluoroacetic Acid / Q000737:chemistry
D000081:Acetamides; D005463:Fluoroacetates; D007287:Inorganic Chemicals; D009930:Organic Chemicals; C014666:N-methyl-bis(trifluoroacetamide); D014269:Trifluoroacetic Acid
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