title: [Content detection of bacterial endotoxin in two kinds of injection by gelatin technique].
abstract: OBJECTIVE
  To detect content of bacterial endotoxin in Yuxingcao and Qingkailing injections by specific and nonspecific tachypleus amebocyte lysate technique for in order to investigate the feasibility of specific tachypleus amebocyte lysate technique for detecting bacterial endotoxin in traditional Chinese drug injections.
  
  
  METHODS
  Different batches of Yuxingcao and Qingkailing injections were detected by specific and nonspecific tachypleus amebocyte lysate kits.
  
  
  RESULTS
  Yuxingcao injection could be detected by specific and nonspecific tachypleus amebocyte lysate technique, Whereas Qingkailing injection could be detected only by specific tachypleus amebocyte lysate.
  
  
  CONCLUSIONS
  Using specific tachypleus amebocyte lysate as a substitute for nonspecific tachypleus amebocyte lysate is an effective method for detecting content of bacterial endotoxin in Qingkailing injection.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Shuangrong
authors.initials: S
authors.lastname: Gao
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Guo
authors.forename: Yan
authors.initials: Y
authors.lastname: Yi
authors.forename: Ran
authors.initials: R
authors.lastname: Hao
authors.forename: Chunying
authors.initials: C
authors.lastname: Li
authors.forename: Chunyu
authors.initials: C
authors.lastname: Cao
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Lianqiang
authors.initials: L
authors.lastname: Hui
authors.forename: Aihua
authors.initials: A
authors.lastname: Liang
mesh_terms: D000818:Animals; D004340:Drug Contamination; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D004731:Endotoxins / Q000032:analysis*; D006737:Horseshoe Crabs; D008033:Limulus Test / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; D004731:Endotoxins