Difference between smokers and non-smokers in the corpus callosum volume.
The purpose of this study was to analyze the effects of smoking on corpus callosum volume. In addition, the relationships between smoking duration, smoking frequency, and corpus callosum volume were analyzed. Magnetic resonance brain images were acquired for 58 normal Korean men (30 smokers (age 32.82±14.12 years) and 28 non-smokers (age 35.49±13.11 years)). The corpus callosum volume was measured using Brain Voyager 2000S/W and was normalized by intracranical volume, which was calculated using cerebral sizes. The corpus callosum volume for smokers was significantly smaller than that for non-smokers. Also, there was a negative correlation between corpus callosum volume and smoking duration. The change of white matter volume (e.g., corpus callosum) might be a primary factor for characterizing the effects of smoking.
Choi
Mi-Hyun
MH
Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, 322 Danwall-dong, Chungju, Chungbuk 380-701, South Korea.
Lee
Su-Jeong
SJ
Yang
Jae-Woong
JW
Kim
Ji-Hye
JH
Choi
Jin-Seung
JS
Park
Jang-Yeon
JY
Jun
Jae-Hoon
JH
Tack
Gye-Rae
GR
Lee
Beob-Yi
BY
Kim
Hyun-Jun
HJ
Chung
Soon-Cheol
SC
D000328:Adult; D003337:Corpus Callosum / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012907:Smoking / Q000473:pathology*