title: X-ray fluorescence camera for imaging of iodine media in vivo.
abstract: X-ray fluorescence (XRF) analysis is useful for measuring density distributions of contrast media in vivo. An XRF camera was developed for carrying out mapping for iodine-based contrast media used in medical angiography. Objects are exposed by an X-ray beam from a cerium target. Cerium K-series X-rays are absorbed effectively by iodine media in objects, and iodine fluorescence is produced from the objects. Next, iodine Kalpha fluorescence is selected out by use of a 58-microm-thick stannum filter and is detected by a cadmium telluride (CdTe) detector. The Kalpha rays are discriminated out by a multichannel analyzer, and the number of photons is counted by a counter card. The objects are moved and scanned by an x-y stage in conjunction with a two-stage controller, and X-ray images obtained by iodine mapping are shown on a personal computer monitor. The scan pitch of the x and y axes was 2.5 mm, and the photon counting time per mapping point was 2.0 s. We carried out iodine mapping of non-living animals (phantoms), and iodine Kalpha fluorescence was produced from weakly remaining iodine elements in a rabbit skin cancer.
authors.affiliation: The 3rd Department of Surgery, Toho University School of Medicine, Tokyo, Japan. hma2kiyo502leo@yahoo.co.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsukiyo
authors.forename: Manabu
authors.initials: M
authors.lastname: Watanabe
authors.forename: Eiichi
authors.initials: E
authors.lastname: Sato
authors.forename: Akihiro
authors.initials: A
authors.lastname: Osawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Enomoto
authors.forename: Jiro
authors.initials: J
authors.lastname: Nagao
authors.forename: Purkhet
authors.initials: P
authors.lastname: Abderyim
authors.forename: Katsuo
authors.initials: K
authors.lastname: Aizawa
authors.forename: Etsuro
authors.initials: E
authors.lastname: Tanaka
authors.forename: Hidezo
authors.initials: H
authors.lastname: Mori
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kawai
authors.forename: Shigeru
authors.initials: S
authors.lastname: Ehara
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Ogawa
authors.forename: Jun
authors.initials: J
authors.lastname: Onagawa
mesh_terms: D000818:Animals; D019187:Cadmium Compounds; D003287:Contrast Media; D005898:Glass; D006321:Heart; D007455:Iodine; D019047:Phantoms, Imaging; D011817:Rabbits; D012878:Skin Neoplasms; D013052:Spectrometry, X-Ray Emission / Q000379:methods*; D013691:Tellurium
chemical_list: D019187:Cadmium Compounds; D003287:Contrast Media; D007455:Iodine; D013691:Tellurium; C028337:cadmium telluride
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