Ultrasound-guided core needle biopsy of cervical lymphadenopathy in patients with lymphoma: the clinical efficacy and factors associated with unsuccessful diagnosis.
This study attempts to identify factors that influence the success or failure of subclassifying 154 cases of neck lymphoma by ultrasound-guided core needle biopsy (UGCNB). Variables including age, gender, nodal size, cutting needle bore, number of core tissues obtained, presence of nodal necrosis or infarct, fragmentation of the specimens and subclassification of lymphoma were reviewed and statistically analyzed to check if they were related to the success of UGCNB. UGCNB was successful in subclassifying lymphoma in 138 (89.7%) cases, in diagnosing lymphoma in 11 (7.1%) and unsuccessful in diagnosing lymphoma in five (3.2%) cases. No complications were encountered. The factors leading to failure in subclassification included the presence of composite lymphoma (p = 0.001), nodal necrosis or infarct (p = 0.001) and insufficiency or fragmentation of the specimens (p < 0.001). UGCNB is a safe and efficient procedure in subclassifying lymphoma. It may obviate surgical biopsy in 89.7% of cases.
Huang
Pei Ching
PC
Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou, Taiwan.
Liu
Chia Yee
CY
Chuang
Wen Yu
WY
Shih
Lee Yung
LY
Wan
Yung Liang
YL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D002648:Child; D003951:Diagnostic Errors; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D007150:Immunohistochemistry; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging*; D008223:Lymphoma / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography