title: Evaluation of mupA EVIGENE assay for determination of high-level mupirocin resistance in Staphylococcus aureus.
abstract: Mupirocin is widely used to decolonize patients carrying Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA). The aim of this study was to determine the presence of high-level mupirocin resistance by a new commercially available mupA genotypic diagnostic product, mupA EVIGENE assay (AdvanDx).
authors.affiliation: AdvanDx, Bygstubben 11, Vedbaek 2950, Denmark. akr@advandx.com
authors.forename: Anne K I
authors.initials: AK
authors.lastname: Rasmussen
authors.forename: Robert L
authors.initials: RL
authors.lastname: Skov
authors.forename: Richard A
authors.initials: RA
authors.lastname: Venezia
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Johnson
authors.forename: Henrik
authors.initials: H
authors.lastname: Stender
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D016712:Mupirocin / Q000494:pharmacology*; D009687:Nuclear Proteins / Q000235:genetics*; D009693:Nucleic Acid Hybridization / Q000379:methods; D012680:Sensitivity and Specificity; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D009687:Nuclear Proteins; C480380:mupA protein, Staphylococcus aureus; D016712:Mupirocin
references.citation: Antimicrob Agents Chemother. 2007 Nov;51(11):3880-6
references.pmid: 17724154
references.citation: J Antimicrob Chemother. 1993 Jun;31(6):909-17
references.pmid: 8360128
references.citation: Infect Control Hosp Epidemiol. 2003 May;24(5):342-6
references.pmid: 12785407
references.citation: J Antibiot (Tokyo). 1978 Apr;31(4):330-5
references.pmid: 659331
references.citation: Nephrol Dial Transplant. 1993;8(3):235-9
references.pmid: 8385291
references.citation: J Antimicrob Chemother. 1996 Jan;37(1):53-63
references.pmid: 8647774
references.citation: J Antimicrob Chemother. 1998 Nov;42(5):577-83
references.pmid: 9848440
references.citation: Clin Infect Dis. 2003 Dec 15;37(12):1629-38
references.pmid: 14689344
references.citation: J Antimicrob Chemother. 1998 Jan;41(1):11-8
references.pmid: 9511032
references.citation: Antimicrob Agents Chemother. 1994 May;38(5):1205-8
references.pmid: 8067768
references.citation: Lancet. 2006 Mar 4;367(9512):731-9
references.pmid: 16517273
references.citation: N Engl J Med. 2002 Jun 13;346(24):1871-7
references.pmid: 12063371