New developments in osteoarthritis. Prevention of injury-related knee osteoarthritis: opportunities for the primary and secondary prevention of knee osteoarthritis.
Where risk factors have been identified in knee and hip osteoarthritis (OA), with few exceptions, no prevention strategies have proven beneficial. The major risk factors for knee OA are advanced age, injury and obesity. However, there is limited or no evidence that they are modifiable or to what degree modifying them is effective in preventing development of knee OA or in preventing symptoms and progressive disease in persons with early OA. The notable exception is the growing epidemic of (sports) injury related knee OA. This review details the biological and clinical data indicating the efficacy of interventions targeting neuromuscular and biomechanical factors that make this subset of OA an attractive public health target, and highlights research opportunities for the future.
Ratzlaff
Charles R
CR
University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3. cratzlaf@interchange.ubc.ca
Liang
Matthew H
MH
D001265:Athletic Injuries / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D006801:Humans; D007718:Knee Injuries / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D020370:Osteoarthritis, Knee / Q000453:epidemiology* / Q000517:prevention & control*; D012307:Risk Factors
Clin Sci (Lond). 1994 Mar;86(3):305-10
8156741
Am J Sports Med. 2009 Feb;37(2):252-9
19182110
Cochrane Database Syst Rev. 2007 Jul 18;(3):CD004019
17636743
Am J Sports Med. 2005 Apr;33(4):524-30
15722283
Knee Surg Sports Traumatol Arthrosc. 2000;8(2):76-82
10795668
J Bone Joint Surg Br. 1993 Mar;75(2):311-5
8444956
Am J Sports Med. 1986 Jul-Aug;14(4):262-6
3728777
Scand J Med Sci Sports. 2008 Oct;18(5):605-14
18208428
Am J Sports Med. 2007 Apr;35(4):564-74
17261567
Br J Sports Med. 2007 Aug;41 Suppl 1:i27-32
17646247
Am J Sports Med. 2000 May-Jun;28(3):336-44
10843124
J Bone Joint Surg Br. 1948 Nov;30B(4):664-70
18894618
Sports Med. 2009;39(11):937-60
19827861
Arthritis Rheum. 2004 Oct;50(10):3145-52
15476248
Phys Sportsmed. 1985 Sep;13(9):75-81
27410700
N Engl J Med. 2008 Sep 11;359(11):1108-15
18784100
Am J Sports Med. 2007 Mar;35(3):359-67
17092928
Scand J Med Sci Sports. 2006 Oct;16(5):329-33
16978252
Pediatr Res. 2003 Aug;54(2):230-6
12736391
Scand J Med Sci Sports. 2009 Jun;19(3):345-55
18510592
Biorheology. 2000;37(1-2):95-107
10912182
Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S16-21
15480060
Am J Sports Med. 2006 Dec;34(12):1933-40
16923826
Curr Opin Rheumatol. 2005 Mar;17(2):195-200
15711235
Osteoarthritis Cartilage. 2008 Aug;16(8):897-902
18203629
Arthritis Rheum. 2004 Sep;50(9):2811-9
15457449
Am J Sports Med. 2003 Jan-Feb;31(1):75-9
12531761
Brain. 1996 Oct;119 ( Pt 5):1751-62
8931595
Instr Course Lect. 2008;57:539-52
18399608
Best Pract Res Clin Rheumatol. 2010 Feb;24(1):47-50
20129199
J Rheumatol. 2007 Apr;34(4):776-84
17361984
Br J Sports Med. 2007 Aug;41 Suppl 1:i33-7
17550919
Am J Sports Med. 2008 Sep;36(9):1717-25
18483197
N Engl J Med. 2008 Sep 11;359(11):1097-107
18784099
Rheumatology (Oxford). 2001 Apr;40(4):432-7
11312383
Am J Sports Med. 1994 Sep-Oct;22(5):632-44
7810787
Clin J Sport Med. 2007 Jan;17(1):17-24
17304001
Am J Sports Med. 2009 Nov;37(11):2173-8
19729363
Ann Rheum Dis. 2004 Mar;63(3):269-73
14962961
Br J Sports Med. 2003;37(5):382-3
14514526
N Engl J Med. 2010 Jul 22;363(4):331-42
20660401
JAMA. 2001 Jul 11;286(2):188-95
11448282
Clin Orthop Relat Res. 1975;(109):184-92
1173360
Am J Sports Med. 2005 Jul;33(7):1003-10
15888716
Am J Sports Med. 1990 May-Jun;18(3):310-5
2372083
Scand J Med Sci Sports. 1998 Dec;8(6):432-8
9863982
Scand J Med Sci Sports. 2011 Dec;21(6):824-32
20456680
Ann Biomed Eng. 2004 Mar;32(3):447-57
15095819
Cochrane Database Syst Rev. 2007 Jul 18;(3):CD005961
17636815
Arthritis Rheum. 2005 Nov;52(11):3507-14
16258919
Cochrane Database Syst Rev. 2005 Oct 19;(4):CD005316
16235401
Arthritis Rheum. 2000 May;43(5):995-1000
10817551
Med Sci Sports Exerc. 2003 Jul;35(7):1118-23
12840631
J Pediatr Nurs. 2009 Feb;24(1):69-74
19159838
Rheum Dis Clin North Am. 2008 Aug;34(3):515-29
18687270
BMJ. 2008 Jul 01;337:a295
18595903
Scand J Med Sci Sports. 1997 Oct;7(5):289-92
9338947
Am J Sports Med. 2007 Mar;35(3):368-73
17267766
Am J Sports Med. 1987 Mar-Apr;15(2):111-6
3578630
Am J Sports Med. 2009 Oct;37(10):1967-73
19574475
Med Sci Sports Exerc. 2008 Feb;40(2):215-22
18202582
Arthritis Rheum. 1998 Aug;41(8):1343-55
9704632
Knee Surg Sports Traumatol Arthrosc. 2007 Apr;15(4):393-401
17216272
BMC Musculoskelet Disord. 2007 May 08;8:39
17488502
Ann Rheum Dis. 2004 Apr;63(4):402-7
15020334
Knee Surg Sports Traumatol Arthrosc. 2008 May;16(5):442-8
18292988
Am J Sports Med. 2008 Jun;36(6):1052-60
18390492
Clin J Sport Med. 2006 May;16(3):223-7
16778542
Am J Sports Med. 2010 Mar;38(3):478-85
20194954
Scand J Med Sci Sports. 2003 Oct;13(5):299-304
14507295
Ann Intern Med. 2000 Sep 5;133(5):321-8
10979876
J Bone Joint Surg Am. 1986 Jan;68(1):71-9
3753605
J Bone Joint Surg Br. 1992 Mar;74(2):247-50
1544962
Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S89-95
15480081
Best Pract Res Clin Rheumatol. 2010 Feb;24(1):39-46
20129198
J Orthop Res. 2000 Jan;18(1):109-15
10716286
Am J Sports Med. 2008 Jan;36(1):48-56
17932399
Am J Sports Med. 1992 Nov-Dec;20(6):686-94
1456362
J Bone Miner Res. 1998 Mar;13(3):500-7
9525351
Br J Sports Med. 2008 Mar;42(3):194-7
17932097
Scand J Med Sci Sports. 2007 Apr;17(2):109-14
17394470
J Electromyogr Kinesiol. 2002 Jun;12(3):205-12
12086815
J Biomech. 2010 Jun 18;43(9):1817-22
20181339
Am J Sports Med. 2008 May;36(5):966-70
18287595
Br J Sports Med. 2010 Sep;44(12):848-55
19158132
Arthritis Rheum. 2003 Aug;48(8):2178-87
12905471
Br J Sports Med. 2009 May;43(5):347-51
18603576
Am J Sports Med. 2009 Oct;37(10):1996-2002
19726623
Exerc Sport Sci Rev. 2009 Jul;37(3):147-53
19550206
Arthritis Rheum. 1998 Apr;41(4):687-93
9550478
Am J Sports Med. 1999 Nov-Dec;27(6):699-706
10569353
Am J Sports Med. 1995 Nov-Dec;23(6):694-701
8600737
Br J Sports Med. 2005 Dec;39(12):932-8
16306502
N Engl J Med. 2002 Jul 11;347(2):81-8
12110735
Am J Sports Med. 2006 Mar;34(3):490-8
16382007
Am J Sports Med. 2008 Aug;36(8):1476-83
18658019
Am J Sports Med. 2001 Mar-Apr;29(2):196-200
11292045
Br J Sports Med. 2009 Jun;43(6):417-22
19372088
J Orthop Res. 2004 Jul;22(4):768-73
15183432
Br J Sports Med. 2009 May;43(5):313-4
19451306
Am J Sports Med. 1994 Jan-Feb;22(1):12-8
8129094
BMJ. 2008 Dec 09;337:a2469
19066253
Am J Sports Med. 2007 Oct;35(10):1756-69
17761605
Am J Sports Med. 2007 May;35(5):729-39
17322130
J Bone Joint Surg Am. 1987 Jan;69(1):2-9
3805067
Am J Sports Med. 2008 Feb;36(2):308-15
17989167
Equine Vet J. 2002 May;34(3):265-9
12108744
Arthritis Rheum. 2005 Mar;52(3):794-9
15751064
Am J Sports Med. 1997 May-Jun;25(3):336-40
9167813