title: Synchronous resection of solitary liver metastases with pancreaticoduodenectomy.
abstract: BACKGROUND
  There is limited information available about the feasibility and benefits of synchronous resection of liver metastases in patients with pancreatic and periampullary cancer undergoing pancreaticoduodenectomy.
  
  
  OBJECTIVE
  We report on our experience with 7 such patients.
  
  
  METHODS
  Analysis of the prospective database was carried out to identify patients who underwent synchronous resection of liver metastases with pancreaticoduodenectomy.
  
  
  METHODS
  Two-hundred and thirty patients underwent pancreaticoduodenectomy for pancreatic and periampullary cancer in our unit between September 2003 and September 2009.
  
  
  METHODS
  The primary aim of our study was to determine the survival benefits and the secondary aim was to evaluate their safety and influence on the results of a pancreaticoduodenectomy.
  
  
  RESULTS
  Seven patients (3%) underwent synchronous resection of a solitary liver metastasis. In these patients, the operative time and intra-operative blood loss was marginally high as compared to the overall cohort of patients undergoing pancreaticoduodenectomy; however, the complication rates and the duration of the hospital stay were not affected. In patients undergoing resection of liver metastasis, there were 4 recurrences over a mean follow-up of 21 months.
  
  
  CONCLUSIONS
  In patients with resectable pancreatic and periampullary cancer, the resection of a solitary liver metastasis can safely be performed together with a pancreaticoduodenectomy; however, its impact on improving survival has yet to be proven.
authors.affiliation: Department of Surgical Gastroenterology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India. adarsh_chaudhary@yahoo.com
authors.forename: Amanjeet
authors.initials: A
authors.lastname: Singh
authors.forename: Tanveer
authors.initials: T
authors.lastname: Singh
authors.forename: Adarsh
authors.initials: A
authors.lastname: Chaudhary
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater / Q000473:pathology / Q000601:surgery; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007432:Intraoperative Period; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods / Q000401:mortality; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult