title: miRNAkey: a software for microRNA deep sequencing analysis.
abstract: BACKGROUND
  MicroRNAs (miRNAs) are short abundant non-coding RNAs critical for many cellular processes. Deep sequencing (next-generation sequencing) technologies are being readily used to receive a more accurate depiction of miRNA expression profiles in living cells. This type of analysis is a key step towards improving our understanding of the complexity and mode of miRNA regulation.
  
  
  RESULTS
  miRNAkey is a software package designed to be used as a base-station for the analysis of miRNA deep sequencing data. The package implements common steps taken in the analysis of such data, as well as adds unique features, such as data statistics and multiple read determination, generating a novel platform for the analysis of miRNA expression. A user-friendly graphical interface is applied to determine the analysis steps. The tabular and graphical output contains general and detailed reports on the sequence reads and provides an accurate picture of the differentially expressed miRNAs in paired samples.
  
  
  METHODS
  See http://ibis.tau.ac.il/miRNAkey
  
  
  BACKGROUND
  nshomron@post.tau.ac.il
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.
authors.forename: Roy
authors.initials: R
authors.lastname: Ronen
authors.forename: Ido
authors.initials: I
authors.lastname: Gan
authors.forename: Shira
authors.initials: S
authors.lastname: Modai
authors.forename: Alona
authors.initials: A
authors.lastname: Sukacheov
authors.forename: Gideon
authors.initials: G
authors.lastname: Dror
authors.forename: Eran
authors.initials: E
authors.lastname: Halperin
authors.forename: Noam
authors.initials: N
authors.lastname: Shomron
mesh_terms: D001483:Base Sequence; D019295:Computational Biology; D030561:Databases, Nucleic Acid; D020869:Gene Expression Profiling; D035683:MicroRNAs / Q000737:chemistry*; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software
chemical_list: D035683:MicroRNAs