title: Phlorotannins from Ecklonia cava (Phaeophyceae): biological activities and potential health benefits.
abstract: The importance of bioactive derivatives as functional ingredients has been well recognized due to their valuable health beneficial effects. Therefore, isolation and characterization of novel functional ingredients with biological activities from seaweeds have gained much attention. Ecklonia cava Kjellman is an edible seaweed, which has been recognized as a rich source of bioactive derivatives mainly, phlorotannins. These phlorotannins exhibit various beneficial biological activities such as antioxidant, anticancer, antidiabetic, anti-human immunodeficiency virus, antihypertensive, matrix metalloproteinase enzyme inhibition, hyaluronidase enzyme inhibition, radioprotective, and antiallergic activities. This review focuses on biological activities of phlorotannins with potential health beneficial applications in functional foods, pharmaceuticals, and cosmeceuticals.
authors.affiliation: Marine Biochemistry Laboratory, Department of Chemistry, Pukyong National University, Busan, Republic of Korea.
authors.forename: Isuru
authors.initials: I
authors.lastname: Wijesekara
authors.forename: Na Young
authors.initials: NY
authors.lastname: Yoon
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology*; D004147:Dioxins / Q000302:isolation & purification* / Q000494:pharmacology*; D005260:Female; D006801:Humans; D051379:Mice; D000459:Phaeophyceae / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D012624:Seaweed / Q000737:chemistry*; D013634:Tannins / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D018926:Anti-Allergic Agents; D000975:Antioxidants; D004147:Dioxins; D010936:Plant Extracts; D013634:Tannins