title: [Application of mitomycin in laryngeal surgery].
abstract: OBJECTIVE
  To investigate the application of mitomycin in laryngeal surgery.
  
  
  METHODS
  Retrospective analysis of the clinical data of 48 patients who had vocal cord lesion involving anterior commissure. The treatment of 30 patients treated with microsurgery and external application of mitomycin, while that of the others were only done with microsurgery.
  
  
  RESULTS
  Among the 30 patients who were treated with microsurgery and mitomycin, only 2 patients of which showed slight adhesion of anterior commissure after surgery. While in the group of microsurgery, there were 6 patients who had adhesion of anterior commissure adhesion after surgery.
  
  
  CONCLUSIONS
  Mitomycin could prevent vocal adhesion after laryngeal surgery.
authors.affiliation: Department of Otolaryngology, China-Japan Friendship Hospital, Beijing, 100029, China.
authors.forename: Honglei
authors.initials: H
authors.lastname: Han
authors.forename: Dazhang
authors.initials: D
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007828:Laryngoscopy / Q000379:methods*; D007830:Larynx / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use*; D012189:Retrospective Studies
chemical_list: D016685:Mitomycin