title: Carbohydrate mouth rinse: does it improve endurance exercise performance?
abstract: It is well known that carbohydrate (CHO) supplementation can improve performance in endurance exercises through several mechanisms such as maintenance of glycemia and sparing endogenous glycogen as well as the possibility of a central nervous-system action. Some studies have emerged in recent years in order to test the hypothesis of ergogenic action via central nervous system. Recent studies have demonstrated that CHO mouth rinse can lead to improved performance of cyclists, and this may be associated with the activation of brain areas linked to motivation and reward. These findings have already been replicated in other endurance modalities, such as running. This alternative seems to be an attractive nutritional tool to improve endurance exercise performance.
authors.affiliation: Laboratory of Applied Nutrition and Metabolism, Department of Biodynamics of Human Movement, School of Physical Education and Sports, University of São Paulo, São Paulo, Brazil. vitor.painelli@usp.br
authors.forename: Vitor
authors.initials: V
authors.lastname: de Salles Painelli
authors.forename: Humberto
authors.initials: H
authors.lastname: Nicastro
authors.forename: Antonio H
authors.initials: AH
authors.lastname: Lancha
mesh_terms: D001642:Bicycling / Q000502:physiology; D002241:Carbohydrates / Q000494:pharmacology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D009067:Mouthwashes / Q000494:pharmacology*; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology
chemical_list: D002241:Carbohydrates; D009067:Mouthwashes
references.citation: J Appl Physiol (1985). 1986 Jul;61(1):165-72
references.pmid: 3525502
references.citation: Med Sci Sports Exerc. 1995 Feb;27(2):200-10
references.pmid: 7723643
references.citation: Scand J Clin Lab Invest. 1967;19(3):218-28
references.pmid: 6048626
references.citation: Biochem J. 1920 Jul;14(3-4):290-363
references.pmid: 16742941
references.citation: J Neurophysiol. 1993 Dec;70(6):2326-36
references.pmid: 8120585
references.citation: Scand J Med Sci Sports. 2010 Feb;20(1):105-11
references.pmid: 19000099
references.citation: Pflugers Arch. 2003 May;446(2):211-9
references.pmid: 12739159
references.citation: Int J Sport Nutr Exerc Metab. 2008 Dec;18(6):585-600
references.pmid: 19164829
references.citation: Int J Sports Med. 2005 May;26(4):281-5
references.pmid: 15795812
references.citation: Int J Sports Med. 1982 Aug;3(3):153-8
references.pmid: 7129724
references.citation: Nat Rev Neurosci. 2006 Nov;7(11):890-901
references.pmid: 17053812
references.citation: Cell. 2003 Oct 31;115(3):255-66
references.pmid: 14636554
references.citation: Cell. 2001 Aug 10;106(3):381-90
references.pmid: 11509186
references.citation: J Physiol. 2009 Apr 15;587(Pt 8):1779-94
references.pmid: 19237430
references.citation: Med Sci Sports Exerc. 1987 Feb;19(1):37-40
references.pmid: 3821453
references.citation: J Sports Sci. 2007 Oct;25(12):1385-92
references.pmid: 17786691
references.citation: J Appl Physiol Respir Environ Exerc Physiol. 1983 Jul;55(1 Pt 1):230-5
references.pmid: 6350247
references.citation: J Appl Physiol (1985). 1986 Sep;61(3):859-63
references.pmid: 3759770
references.citation: Int J Sport Nutr Exerc Metab. 2009 Aug;19(4):400-9
references.pmid: 19827464
references.citation: Int J Sports Med. 1997 Feb;18(2):125-9
references.pmid: 9081269
references.citation: J Appl Physiol (1985). 1998 Apr;84(4):1413-7
references.pmid: 9516211
references.citation: Int J Sports Med. 1987 Apr;8(2):99-104
references.pmid: 3298088
references.citation: Nature. 1966 Apr 16;210(5033):309-10
references.pmid: 5954569
references.citation: Med Sci Sports Exerc. 1993 Nov;25(11):1211-24
references.pmid: 8289607
references.citation: Chem Senses. 2006 May;31(4):351-7
references.pmid: 16495435
references.citation: Med Sci Sports Exerc. 2004 Dec;36(12):2107-11
references.pmid: 15570147
references.citation: Science. 2003 Aug 8;301(5634):850-3
references.pmid: 12869700
references.citation: J Physiol. 1999 Mar 1;515 ( Pt 2):579-89
references.pmid: 10050023
references.citation: Med Sci Sports Exerc. 2004 Sep;36(9):1543-50
references.pmid: 15354036
references.citation: Brain. 2001 Sep;124(Pt 9):1720-33
references.pmid: 11522575