title: Correlation between plasma and saliva adrenocortical hormones in response to submaximal exercise.
abstract: This study examined the relationships between plasma and saliva adrenocortical hormones in response to long-duration submaximal exercise. In nine healthy, physically active, female volunteers, blood and saliva samples were taken at rest and every 30 min during a 120-min cycling trial at 50-55% VO(2max) for cortisol and dehydroepiandrosterone (DHEA) analysis. Correlation analysis revealed a moderate but significant relationship between plasma and saliva cortisol (r = 0.35, P < 0.02) and plasma and saliva DHEA (r = 0.47, P < 0.001) during the submaximal exercise. When expressed in percent of resting values, the correlations between the plasma and saliva concentrations were higher for both hormones during the exercise (cortisol: r = 0.72; DHEA: r = 0.68, P < 0.001). The results thus suggest that, even under prolonged exercise conditions, non-invasive saliva samples may offer a practical approach to assessing pituitary-adrenal function, especially when compared with individual basal values.
authors.affiliation: Laboratoire AMAPP, EA 4248, UFR STAPS, Université d'Orléans, Allée du Château, BP 6237, 45062 Orléans Cedex 2, France.
authors.forename: R
authors.initials: R
authors.lastname: Thomasson
authors.forename: A
authors.initials: A
authors.lastname: Baillot
authors.forename: L
authors.initials: L
authors.lastname: Jollin
authors.forename: A-M
authors.initials: AM
authors.lastname: Lecoq
authors.forename: V
authors.initials: V
authors.lastname: Amiot
authors.forename: F
authors.initials: F
authors.lastname: Lasne
authors.forename: K
authors.initials: K
authors.lastname: Collomp
mesh_terms: D001642:Bicycling; D003687:Dehydroepiandrosterone / Q000032:analysis* / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis* / Q000097:blood*; D012463:Saliva / Q000737:chemistry*; D055815:Young Adult
chemical_list: D003687:Dehydroepiandrosterone; D006854:Hydrocortisone
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