title: Pyridine activation via copper(I)-catalyzed annulation toward indolizines.
abstract: The copper(I)-catalyzed regioselective [3 + 2] cyclization of pyridines toward alkenyldiazoacetates leading to functionalized indolizine derivatives is reported. A broad range of pyridine derivatives (including quinoline and isoquinoline) is compatible with this cyclization reaction. The process represents the first successful example of metal-catalyzed cyclization of a π-deficient heterocyclic system with alkenyldiazo compounds.
authors.affiliation: Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al CSIC, Universidad de Oviedo, Julián Clavería 8, 33006 Oviedo, Spain. barluenga@uniovi.es
authors.forename: José
authors.initials: J
authors.lastname: Barluenga
authors.forename: Giacomo
authors.initials: G
authors.lastname: Lonzi
authors.forename: Lorena
authors.initials: L
authors.lastname: Riesgo
authors.forename: Luis A
authors.initials: LA
authors.lastname: López
authors.forename: Miguel
authors.initials: M
authors.lastname: Tomás