Clinical Inquiries: How can we keep impaired glucose tolerance and impaired fasting glucose from progressing to diabetes?
Lifestyle changes and some drugs can help. Lifestyle interventions aimed at weight loss of 5% to 10% of body weight along with moderate aerobic exercise such as brisk walking for 150 minutes a week are the most effective means to prevent impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) from progressing to diabetes (strength of recommendation [SOR]: A, several meta-analyses, including a recent Cochrane review).
Swanson
Ana
A
Tacoma Family Medicine, Tacoma, Wash, USA.
Watrin
Kerry
K
Wilder
Laura
L
D020909:Acarbose / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D018450:Disease Progression; D018149:Glucose Intolerance / Q000150:complications*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008019:Life Style; D011236:Prediabetic State / Q000175:diagnosis; D000077154:Rosiglitazone; D045162:Thiazolidinediones / Q000627:therapeutic use; D015431:Weight Loss
D000806:Angiotensin-Converting Enzyme Inhibitors; D007004:Hypoglycemic Agents; D045162:Thiazolidinediones; D000077154:Rosiglitazone; D020909:Acarbose