title: Interpretation of the results of OVER in the context of EVAR trial, DREAM, and the EUROSTAR registry.
abstract: Several early studies have shown the benefit of endovascular aneurysm repair in reducing procedure-related mortality and morbidity of open aneurysm repair. Three prospective randomized trials have addressed the advantages and disadvantages of the two procedures. These studies had shown some conflicting findings in survival and complications. We reviewed the largest registry for endovascular abdominal aortic repair and the three randomized trials to evaluate the similarities and differences in their outcomes. Cross-comparison of operative, aneurysm-related and all-cause mortality is presented. Patient characteristics, device specifications, procedure morbidity and reintervention rate of each study are evaluated.
authors.affiliation: Department of Surgery, Division of Vascular and Endovascular Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. mbmalas@jhmi.edu
authors.forename: Mahmoud B
authors.initials: MB
authors.lastname: Malas
authors.forename: Julie A
authors.initials: JA
authors.lastname: Freischlag
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D019317:Evidence-Based Medicine; D006801:Humans; D015337:Multicenter Studies as Topic; D018579:Patient Selection; D011446:Prospective Studies; D011474:Prosthesis Design; D016032:Randomized Controlled Trials as Topic; D012042:Registries; D012086:Reoperation; D012107:Research Design; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome