title: Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia.
authors.forename: A D
authors.initials: AD
authors.lastname: Bulgar
authors.forename: M
authors.initials: M
authors.lastname: Snell
authors.forename: J R
authors.initials: JR
authors.lastname: Donze
authors.forename: E B
authors.initials: EB
authors.lastname: Kirkland
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Xu
authors.forename: S L
authors.initials: SL
authors.lastname: Gerson
authors.forename: L
authors.initials: L
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols; D017209:Apoptosis / Q000187:drug effects; D015153:Blotting, Western; D049109:Cell Proliferation / Q000187:drug effects; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000037:antagonists & inhibitors; D004249:DNA Damage / Q000187:drug effects; D004260:DNA Repair / Q000187:drug effects*; D004357:Drug Synergism; D006801:Humans; D006898:Hydroxylamines / Q000494:pharmacology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014407:Tumor Cells, Cultured; D051981:Uracil-DNA Glycosidase / Q000378:metabolism; D014740:Vidarabine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D006898:Hydroxylamines; D012333:RNA, Messenger; C005214:methoxyamine; D004248:DNA (Cytosine-5-)-Methyltransferases; D051981:Uracil-DNA Glycosidase; D014740:Vidarabine; C024352:fludarabine