[Correlation of phospholipid composition and physicochemical characteristics of lipids in tissues of the root vole Microtus oeconomus of different ages].
There was performed a comparative analysis of phospholipids and of lipid physicochemical characteristics in spleen, blood erythrocytes, and liver of the root voles caught in the natural environmental habitation at different phases of the population cycle, as well as of the animals born and raised throughout the entire life in vivarium, depending on the animals' sex and age. The age-related changes in the phospholipid composition have been established to correlate with lipid physicochemical characteristics, while the scale and direction of the changes depend on the tissue functional role, the initial level of the antioxidative activity (AOA) of its lipids, and sex of the animals. In the process of the organism aging, parameters of the system of regulation of lipid peroxidation change not unidirectionally; in group of animals of the same age, individuals with different biochemical characteristics can be present. Under natural conditions of habitation the degree of expression of age-related changes is modified by populational factors.
Shevchenko
O G
OG
Zagorskaia
N G
NG
Shishkina
L N
LN
D000375:Aging / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D003411:Arvicolinae / Q000378:metabolism*; D005260:Female; D050356:Lipid Metabolism / Q000502:physiology*; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D010743:Phospholipids / Q000378:metabolism*
D000975:Antioxidants; D010743:Phospholipids