title: Regional muscle and whole-body composition factors related to mobility in older individuals: a review.
abstract: OBJECTIVE
  To describe previously reported locomotor muscle and whole-body composition factors related to mobility in older individuals.
  
  
  METHODS
  A narrative review of the literature, including a combination of search terms related to muscle and whole-body composition factors and to mobility in older individuals, was carried out. Statistical measures of association and risk were consolidated to summarize the common effects between studies.
  
  
  RESULTS
  Fifty-three studies were reviewed. Muscle and whole-body factors accounted for a substantial amount of the variability in walking speed, with coefficients of determination ranging from 0.30 to 0.47. Muscle power consistently accounted for a greater percentage of the variance in mobility than did strength. Risks associated with high fat mass presented a minimum odds ratio (OR) of 0.70 and a maximum OR of 4.07, while the minimum and maximum ORs associated with low lean mass were 0.87 and 2.30 respectively. Whole-body and regional fat deposits accounted for significant amounts of the variance in mobility.
  
  
  CONCLUSIONS
  Muscle power accounts for a greater amount of the variance in the level of mobility in older individuals than does muscle strength. Whole-body fat accounts for a greater amount of the variance in level of mobility than does whole-body lean tissue. Fat stored within muscle also appears to increase the risk of a mobility limitation in older individuals.
authors.affiliation: Department of Physical Therapy, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Jason
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authors.lastname: Kidde
authors.forename: Robin
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authors.lastname: Marcus
authors.forename: Lee
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authors.lastname: Dibble
authors.forename: Sheldon
authors.initials: S
authors.lastname: Smith
authors.forename: Paul
authors.initials: P
authors.lastname: Lastayo
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