title: Aerobic exercise capacity and pulmonary function in athletes with and without type 1 diabetes.
abstract: OBJECTIVE
  To compare the aerobic exercise capacity and pulmonary function between athletes with and without type 1 diabetes.
  
  
  METHODS
  Fifty-one adult age-matched individuals were assessed in random order to the maximum volume of O(2) consumption (Vo(2 peak max)) (ml/kg/min), anaerobic threshold (ml/kg/min), peak pulmonary ventilation (Ve), heart rate (beats per min), time to exhaustion (min), forced vital capacity (FEV) (%), forced expiratory volume in the first second (FEV1) (%), total lung capacity (TLC) (%), and lung diffusion capacity for carbon monoxide (DL(CO)) (%). Individuals were 27 with type 1 diabetes: 15 athletes (ADM) and 12 nonathletes (NADM); and 24 healthy individuals: 12 ADM and 12 NADM. Duration of diabetes was 14.6 ± 6.2 and 15.2 ± 6.7 years in ADM and NADM, respectively.
  
  
  RESULTS
  Vo(2 peak) (max) was higher in ADM than in NADM (P < 0.001). The anaerobic threshold was lower in subjects with type 1 diabetes than in control subjects (P < 0.001). FEV1 was lower in ADM than in other groups (NADM, athletes control, and nonathletes control, P < 0.001).
  
  
  CONCLUSIONS
  Aerobic capacity in subjects with type 1 diabetes with programmed exercise is similar to the capacity of normal athletes despite lower anaerobic threshold and FEV1.
authors.affiliation: Diabetes Center, Department of Medicine, Endocrinology Division, Federal University of São Paulo, São Paulo, Brazil. william.komatsu@unifesp.br
authors.forename: William R
authors.initials: WR
authors.lastname: Komatsu
authors.forename: Turibio L
authors.initials: TL
authors.lastname: Barros Neto
authors.forename: Antonio R
authors.initials: AR
authors.lastname: Chacra
authors.forename: Sergio A
authors.initials: SA
authors.lastname: Dib
mesh_terms: D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology*; D056352:Athletes; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D055815:Young Adult
references.citation: Diabetes Care. 2004 Mar;27(3):752-7
references.pmid: 14988297
references.citation: Klin Med (Mosk). 2008;86(1):54-7
references.pmid: 18326287
references.citation: Pediatr Diabetes. 2005 Sep;6(3):145-9
references.pmid: 16109070
references.citation: Am J Med Sci. 2001 Sep;322(3):127-32
references.pmid: 11570776
references.citation: Am J Med. 1997 Dec;103(6):504-13
references.pmid: 9428834
references.citation: Am J Med. 1991 Oct;91(4):371-6
references.pmid: 1951381
references.citation: Eur Respir J. 2002 Dec;20(6):1406-12
references.pmid: 12503696
references.citation: Am J Respir Crit Care Med. 1995 Dec;152(6 Pt 1):2185-98
references.pmid: 8520796
references.citation: Diabetes Care. 2003 Jun;26(6):1915-8
references.pmid: 12766133
references.citation: Pediatr Pulmonol. 1992 Jul;13(3):155-60
references.pmid: 1437329
references.citation: Bull Eur Physiopathol Respir. 1982 Jan-Feb;18(1):51-8
references.pmid: 7053776
references.citation: Diabetes Care. 2010 Jan;33 Suppl 1:S62-9
references.pmid: 20042775
references.citation: Am Rev Respir Dis. 1976 Jan;113(1):37-41
references.pmid: 1247213