title: Acute toxicity of emamectin benzoate and its desmethyl metabolite to Eohaustorius estuarius.
abstract: Emamectin benzoate is one of the active ingredients of the anti-sealice drug SLICE. Ten-day acute sediment lethal tests (10-d LC50) of emamectin benzoate and its desmethyl metabolite (AB1) were conducted to determine LC50 values using a sensitive representative West Coast amphipod crustacean, Eohaustorius estuarius. The 10-d LC50s of emamectin benzoate and AB1 to E. estuarius were 0.185 and 0.019 mg/kg wet weight sediment (0.146 and 0.015 mg/kg dry wt), respectively. The degradation properties of emamectin benzoate and AB1 during the 10-d period were also measured and described. No obvious decay patterns were observed for either emamectin benzoate and AB1 over the 10-d period.
authors.affiliation: Water Quality Monitoring and Surveillance Division, Environment Canada, 201-401 Burrard Street, Vancouver, British Columbia, V6C 3S5. jen-ni.kuo@ec.gc.ca
authors.forename: Jen-Ni
authors.initials: JN
authors.lastname: Kuo
authors.forename: Craig
authors.initials: C
authors.lastname: Buday
authors.forename: Graham
authors.initials: G
authors.lastname: van Aggelen
authors.forename: Michael George
authors.initials: MG
authors.lastname: Ikonomou
authors.forename: John
authors.initials: J
authors.lastname: Pasternak
mesh_terms: D033304:Amphipoda / Q000187:drug effects*; D000818:Animals; D000977:Antiparasitic Agents / Q000032:analysis / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D019015:Geologic Sediments / Q000737:chemistry; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000032:analysis / Q000633:toxicity; D023382:Toxicity Tests, Acute; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity
chemical_list: C554435:4'-amino-4'-avermectin B1 benzoate; D000977:Antiparasitic Agents; D014874:Water Pollutants, Chemical; D007559:Ivermectin; C108024:emamectin benzoate