Bone void fillers.
For this technology overview, the tools of evidence-based medicine were used to summarize information on the effectiveness and clinical outcomes related to the usage of bone void fillers- specifically, synthetic graft materials. Comprehensive literature searches were conducted to address five key questions, which the task force that prepared the report posed as follows. Question 1 addressed the use of synthetic bone void fillers alone. Question 2 was designed to determine whether synthetic bone void fillers could successfully serve as graft extenders and eliminate the need for iliac crest bone graft. Questions 3, 4, and 5 addressed the use of allografts as a comparison with synthetic fillers because clinical results with allografts are perceived as being much closer to autografts in these areas of the spine.
Kirkpatrick
John S
JS
University of Florida, Jacksonville, FL, USA.
Cornell
Charles N
CN
Hoang
Bang H
BH
Hsu
Wellington
W
Watson
J Tracy
JT
Watters
William C
WC
Turkelson
Charles M
CM
Wies
Janet L
JL
Anderson
Sara
S
D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods / Q000639:trends*; D019317:Evidence-Based Medicine; D006801:Humans; D013123:Spinal Fusion / Q000379:methods; D016896:Treatment Outcome
D018786:Bone Substitutes