title: Fibrosing mediastinitis causing acute ostial left main myocardial infarction.
abstract: This report describes an unusual etiology of acute coronary syndrome. A 48-year-old female presented with anginal chest discomfort and was found to have evidence of acute pulmonary edema requiring mechanical ventilation. She underwent emergency coronary angiography and stenting of the culprit left-main artery ostial discrete stenosis. Subsequent echocardiography and magnetic resonance imaging revealed severe aortic regurgitation and periaortic valve tissue infiltrates. Pericardiectomy and mediastinal mass biopsy were performed which indicated the pathology of fibrosing mediastinitis.
authors.affiliation: National University Heart Centre 5, Lower Kent Ridge Road, Singapore 119074. jaddatu74@gmail.com
authors.forename: Domingo T
authors.initials: DT
authors.lastname: Addatu
authors.forename: Huay Cheem
authors.initials: HC
authors.lastname: Tan
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D001022:Aortic Valve Insufficiency / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001706:Biopsy; D017023:Coronary Angiography; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008480:Mediastinitis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011654:Pulmonary Edema / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D012598:Sclerosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D012770:Shock, Cardiogenic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D018084:Ultrasonography, Interventional