title: Oral presentation of malignant mesothelioma.
abstract: We report a case of metastatic mesothelioma presenting as an oral metastasis in a 46-year-old patient. The patient presented with 2 polypoid lesions that appeared to be benign on the dorsum of the tongue. Excisional biopsy showed the presence of metastatic carcinoma that on further investigation proved to be mesothelioma. The initial presentation of mesothelioma as an oral metastasis is not previously reported. This article highlights the importance of biopsy and histopathological diagnosis in presumed benign lesions and the role of the general dental practitioner in screening for oral neoplasms.
authors.affiliation: Department of Clinical Oncology, Weston Park Hospital, Sheffield, UK. Louise.Murray@sth.nhs.uk
authors.forename: Louise J
authors.initials: LJ
authors.lastname: Murray
authors.forename: Jon
authors.initials: J
authors.lastname: Higham
authors.forename: S Kim
authors.initials: SK
authors.lastname: Suvarna
authors.forename: Geoffrey T
authors.initials: GT
authors.lastname: Craig
authors.forename: Caroline H
authors.initials: CH
authors.lastname: Bridgewater
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Fisher
authors.forename: Martin H
authors.initials: MH
authors.lastname: Thornhill
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D005971:Glutamates / Q000627:therapeutic use; D006147:Guanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008654:Mesothelioma / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D000068437:Pemetrexed; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine; D002945:Cisplatin