[Comparison of the therapeutic effects of PTBD and PTBS in treatment of malignant obstructive jaundice].
OBJECTIVE
To summarize and compare the short-term and long-term clinical efficacy of percutaneous transhepatic biliary drainage (PTBD) and percutaneous transhepatic biliary stent (PTBS) in the treatment of malignant obstructive jaundice.


METHODS
210 cases of malignant obstructive jaundice underwent interventional therapy, of which 161 cases of drainage catheters placement and 49 cases of metallic stent implantation. Follow-up information was obtained through telephone review or check-up records.


RESULTS
The technical success rate of technique was 100%. At 3 - 5 days after treatment, the serum total bilirubin in 15 metallic stent-treated patients was decreased by (178.04 +/- 42.32) micromol/L, and direct bilirubin by (83.97 +/- 23.63) micromol/L. Compared with those of 28 cases treated with drainage catheters: (95.67 +/- 34.28) micromol/L and (49.84 +/- 28.21) micromol/L, there were statistically significant differences between the two groups (P = 0.017 and P = 0.035). At 6 - 9 days after treatment, the serum total bilirubin in 28 cases of metallic stent group was decreased by (188.22 +/- 79.90) micromol/L, and that in 126 cases of drainage catheter group decreased by (141.39 +/- 65.32) micromol/L. The difference was statistically significant (P = 0.014). But the decline value of direct bilirubin had no significant difference. The median patency period and the median survival time of the drainage catheter group were 60 and 148 days, respectively, those of metallic stent group were 197 days and 245 days. There were statistically significant differences between the two groups (P < 0.05).


CONCLUSIONS
The results of this study indicate that the short-term and long-term efficacies of metallic stent implantation are better than those of catheter drainage technique.
Bai
Ai-Guo
AG
Department of Interventional Radiology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zheng
Chuan-Sheng
CS
Zhou
Guo-Feng
GF
Liang
Hui-Min
HM
Feng
Gan-Sheng
GS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000150:complications*; D001663:Bilirubin / Q000097:blood; D004322:Drainage / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications; D006801:Humans; D041781:Jaundice, Obstructive / Q000097:blood / Q000209:etiology / Q000628:therapy*; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications; D015607:Stents; D015996:Survival Rate
D001663:Bilirubin