The long and short of fertility and longevity.
Does life span extension come with a reproductive trade-off? In a recent report published in Nature, Greer et al. (2010) show that in the nematode worm C. elegans, life span extension, as a consequence of deficiencies in histone methylation, requires an intact germline and ongoing fertility.
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Yousin
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Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute for Aging Research, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute of Aging Research, Guangdong Medical College, Dongguan 523808, China.
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