Objectively measured physical activity is negatively associated with plasma adiponectin levels in minority female youth.
Objective. To evaluate the relationship between adiponectin and physical activity (PA) in minority female youth. Methods. Plasma adiponectin was measured in 39 females (mean age 9.2 ± 0.9 years; 30 Latina, 9 African-American; 56% overweight). PA was assessed by accelerometry. Mean minutes per day spent in daily PA (DPA) (≥3 metabolic equivalents (METs)), moderate PA (MPA)(4-7 METs), vigorous PA (VPA)(≥7 METs), and moderate-to-vigorous PA (MVPA)(≥4 METs) were calculated. The association between adiponectin and PA, controlling for age, fat weight, lean weight, and insulin sensitivity (SI) was analyzed using linear regression. Results. Adiponectin correlated with fat weight (r = -0.43, P < .01) and SI (r = 0.52, P < .01). Minutes spent in DPA (β = -0.40, P = .02), MPA (β = -0.36, P = .04), or MVPA (β = -0.37, P = .03) were predictors of adiponectin in the adjusted model. Conclusions. Higher PA levels were related to lower adiponectin levels. Potential mechanisms include upregulation of adiponectin receptors or an increase in high-molecular weight adiponectin with increasing PA.
Emken
B Adar
BA
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Richey
Joyce
J
Belcher
Britni
B
Hsu
Ya-Wen
YW
Spruijt-Metz
Donna
D
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