[Problem aspects of diagnostics and surgical treatment of Itsenko-Cushing syndrome].
The author has analyzed results of examination and treatment of 142 patients with Itsenko-Cushing syndrome. It was established that careful observation of the diagnostic algorithm (estimation of the blood cortisol, adrenocorticotropic hormone level, tests with 8 mg dexamethasone, MRI of adrenal glands and hypophysis with obligatory using contrast paramagnetic substances) allowed differentiation of basic forms of endogenous hypercorticalism: Itsenko-Cushing disease in 83.1%, cortisol-productive adenoma cases in 16.9%. This approach ensures rational strategy of treatment, good outcomes and high quality of life.
Maĭstrenko
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D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000311:Adrenal Glands / Q000473:pathology; D000328:Adult; D000368:Aged; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult