[New aspects of MRI for diagnostics of large vessel vasculitis and primary angiitis of the central nervous system].
Vasculitis is a rare disease and clinical symptoms are often unspecific. Accurate and early diagnosis is mandatory in order to prevent complications, such as loss of vision or stroke. Imaging techniques can contribute to establishing a definite diagnosis and to evaluate disease activity and the extent of the disease in various vascular regions. Conventional imaging methods, such as computed tomography (CT) and magnetic resonance (MR) angiography, as well as digital subtraction angiography allow the vessel lumen but not the vessel wall to be depicted. However, vasculitis is a disease which primarily affects the vessel wall, therefore conventional imaging modalities often fail to make a definite diagnosis. Recently black-blood high resolution MR in vivo imaging has been used to visualize cervical and intracranial vasculitis. This review article presents imaging protocols for intracranial and cervical black-blood MR imaging and clinical cases with large vessel vasculitis and vasculitis of the central nervous system. Furthermore the current literature, examples of the most common differential diagnoses of cervical and cranial arteriopathy and the potential of other imaging modalities, such as PET/CT and ultrasound will be discussed.
Saam
T
T
Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland. tobias.saam@med.uni-muenchen.de
Habs
M
M
Cyran
C C
CC
Grimm
J
J
Pfefferkorn
T
T
Schüller
U
U
Reiser
M F
MF
Nikolaou
K
K
D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D001018:Aortic Diseases / Q000175:diagnosis / Q000473:pathology; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000473:pathology; D001158:Arteries / Q000473:pathology; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000473:pathology; D005260:Female; D013700:Giant Cell Arteritis / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012680:Sensitivity and Specificity; D056647:Systemic Vasculitis / Q000175:diagnosis* / Q000473:pathology; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed; D020293:Vasculitis, Central Nervous System / Q000175:diagnosis* / Q000473:pathology; D055815:Young Adult
Curr Opin Neurol. 2004 Jun;17(3):317-36
15167068
Rheumatology (Oxford). 2009 May;48(5):537-41
19233887
Cerebrovasc Dis. 2008;26(1):23-9
18511868
AJNR Am J Neuroradiol. 2007 Oct;28(9):1722-7
17885247
Radiologe. 2010 Apr;50(4):355-65
20221580
Radiology. 2007 Jul;244(1):64-77
17581895
J Cardiovasc Magn Reson. 2009 Oct 27;11:41
19860875
Internist (Berl). 2009 Nov;50(11):1200-9
19838657
Clin Nucl Med. 2009 Nov;34(11):749-52
19851167
J Nucl Med. 2009 Oct;50(10):1611-20
19759117
Arch Neurol. 2009 Jun;66(6):704-9
19506130
N Engl J Med. 2003 Jul 10;349(2):160-9
12853590
Eur Radiol. 2009 Sep;19(9):2255-60
19396444
Neuroradiology. 2007 Jun;49(6):471-9
17345075
Radiographics. 2004 May-Jun;24(3):773-86
15143227
J Magn Reson Imaging. 2005 Nov;22(5):628-33
16215965
Rheumatology (Oxford). 2007 Jan;46(1):6-15
17043053
N Engl J Med. 2002 Jul 25;347(4):261-71
12140303
J Magn Reson Imaging. 2000 May;11(5):481-7
10813857
Arthritis Rheum. 2009 Apr;60(4):1193-200
19333926
Hum Pathol. 2008 Apr;39(4):514-26
18294676
Br J Radiol. 2010 Sep;83(993):e182-4
20739338
Ann Rheum Dis. 2009 Aug;68(8):1369-70
19605745
J Magn Reson Imaging. 2006 Aug;24(2):423-7
16791865
Curr Opin Rheumatol. 2009 Jan;21(1):19-28
19077714
Neurology. 2010 May 18;74(20):1651-3
20479365
Clin Rheumatol. 2008 May;27(5):663-6
18172573
Nat Clin Pract Rheumatol. 2008 Sep;4(9):460-1
18628728
Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):234-9
15528475
N Engl J Med. 1997 Nov 6;337(19):1336-42
9358127
Pract Neurol. 2009 Oct;9(5):256-67
19762885
AJNR Am J Neuroradiol. 2000 Apr;21(4):766-9
10782793
AJR Am J Roentgenol. 2005 Jan;184(1):283-7
15615989
Curr Opin Rheumatol. 2008 Jan;20(1):29-34
18281854
Radiology. 2004 Dec;233(3):878-82
15498898