Imaging characteristics of angiomatoid fibrous histiocytoma of bone.
We present the first report of a patient with angiomatoid fibrous histiocytoma of bone in the radiology literature. This tumor initially eluded diagnosis due to its similarities with chronic hematoma and aneurysmal bone cyst. Only two cases of angiomatoid fibrous histiocytoma have been reported in the radiology literature and both of these lesions were in the soft tissues. The fairly distinctive findings in our patient of multiple large cystic chambers with fluid-fluid levels are similar to the findings in the two soft tissue case reports, suggesting that imaging may be used to suggest this specific diagnosis regardless of location, especially in the clinical setting of unexplained hematoma or anemia. Mention of this diagnosis in the radiology report may aid in the final diagnosis at pathology, because special techniques, including fluorescent in situ hybridization, must be applied in order to fully evaluate for the diagnosis.
Petrey
W Banks
WB
Department of Radiology, UVA Health System, Box 800170, Charlottesville, VA 22908, USA. WP5U@hscmail.mcc.virginia.edu
LeGallo
Robin D
RD
Fox
Michael G
MG
Gaskin
Cree M
CM
D001859:Bone Neoplasms / Q000175:diagnosis*; D002675:Child, Preschool; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis*; D006801:Humans; D007512:Ischium / Q000000981:diagnostic imaging* / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods*
Genes Chromosomes Cancer. 2007 Dec;46(12):1051-60
17724745
Radiographics. 1994 Jul;14(4):807-26; quiz 827-8
7938770
Cancer. 1979 Dec;44(6):2147-57
228836
Mod Pathol. 2010 Jan;23(1):93-7
19801966
Clin Cancer Res. 2007 Dec 15;13(24):7322-8
18094413
Skeletal Radiol. 2004 Jun;33(6):330-6
15138727
Am J Surg Pathol. 2010 Feb;34(2):279-85
20090505
Cancer Genet Cytogenet. 2000 Sep;121(2):109-16
11063792
Hum Pathol. 1991 Jun;22(6):563-8
1650754
Am J Surg Pathol. 2005 Dec;29(12):1673-9
16327442
Am J Surg Pathol. 1990 Dec;14(12):1126-32
2174650
Skeletal Radiol. 2004 Oct;33(10):604-8
15258704
Eur Radiol. 2006 Dec;16(12):2644-51
16612549