[Xanthogranuloma of the parotid gland in adults].
Juvenile xanthogranuloma (JXG) is a cutaneous non-Langerhans cell histiocytosis affecting infants. We report the first case of JXG in the parotid gland of an adult.


METHODS
A 52 year-old man consulted for a painful swelling of the left parotid region, progressively increasing. On physical examination, the mass was 4 cm in diameter. A second 1.5 cm diameter tumor was found in the right parotid region. MRI revealed masses with heterogeneous hypodense on T1-weighted images and with hyper dense on T2 weighted images associated with heterogeneous enhancement after gadolinium injection. The superficial and deep lobes of the parotid gland were involved. Per-operative left-side exploration revealed a lipomatous degeneration of the parotid gland and facial nerve. A lower polar parotidectomy was performed. The histological examination identified a parotid xanthogranuloma.


CONCLUSIONS
The JXG is usually revealed by cutaneous lesions. In fact, the morphological, immunohistochemical, and ultrastructural features of this affection lead to its diagnosis. Extra-cutaneous localizations are less frequent. The differential diagnosis is X histiocytosis.
Dhouib
H
H
Service ORL, CHU Habib Bourguiba, 3029 Sfax, Tunisie. houria.dhouib@tunet.tn
Hammami
B
B
Sellami
M
M
Mnif
L
L
Boudawara
T
T
Ghorbel
A
A
D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D003287:Contrast Media; D003937:Diagnosis, Differential; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D008264:Macrophages / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000175:diagnosis* / Q000473:pathology; D014746:Vimentin / Q000032:analysis; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D003287:Contrast Media; D005682:Gadolinium; D014746:Vimentin; C067980:CD68 antigen, human; D000097382:CD68 Molecule