Acquired partial lipodystrophy with C3 hypocomplementemia and antiphospholipid and anticardiolipin antibodies.
Acquired partial lipodystrophy is an extremely rare condition of unknown etiology characterized by progressive loss of fat of the face, neck, trunk, and upper extremities. It usually begins during childhood and is more common in girls. C(3) hypocomplementemia is seen in 70% of patients with acquired partial lipodystrophy. Unlike generalized forms of the disease, no insulin resistance occurs. We present three boys with acquired partial lipodystrophy having C(3) hypocomplementemia. In addition, one of them had antiphospholipid and anticardiolipin antibodies.
Yavuz
Sevgi
S
Department of Pediatrics, Cukurova University Hospital, Adana, Turkey. drsyavuz@gmail.com
Acartürk
Tahsin Oğuz
TO
D000273:Adipose Tissue / Q000473:pathology; D017153:Antibodies, Anticardiolipin / Q000097:blood*; D002648:Child; D003176:Complement C3 / Q000172:deficiency* / Q000378:metabolism*; D019066:Facies; D006801:Humans; D052496:Lipodystrophy, Familial Partial / Q000276:immunology* / Q000473:pathology*; D008297:Male
D017153:Antibodies, Anticardiolipin; D003176:Complement C3