Effects of consuming diets containing various fats or citrus flavanones on plasma lipid and urinary F2-isoprostane concentrations in overweight cats.
OBJECTIVE
To compare in overweight cats the effects of feeding moderate-energy diets with moderate fat content but with saturated fat (beef tallow), saturated fat plus citrus flavanones, or monounsaturated fat (olive oil) on plasma lipids and urinary F2-isoprostane concentrations.


METHODS
20 overweight cats with mean+/-SD body weight of 5.2+/-0.2 kg and mean body condition score of 7.8+/-0.2 (9-point scale).


METHODS
Body weight, plasma total cholesterol and triacylglycerol concentrations, and urinary F2-isoprostane concentration (as marker of oxidative stress) were measured at the beginning of the study, when the cats were fed a maintenance diet, and after 1, 3, and 5 months of consuming test diets.


RESULTS
In overweight cats, citrus flavanones supplementation of the saturated fat diet was associated with lower energy intake and with lower plasma lipids and urinary F2-isoprostane concentrations than in cats fed the saturated fat alone. Monounsaturated fat feeding resulted in lower food intake than in cats fed saturated fat. However, plasma lipids concentrations remained within reference limits throughout the study.


CONCLUSIONS
Although the clinical relevance of these findings is unknown, the significant differences detected indicated that lower energy intake with citrus flavanones supplementation or with substitution of saturated fat for monounsaturated fat could be good strategies for decreasing plasma lipids concentration and oxidative stress in overweight cats, even before considerable loss of body weight is observed.
Jeusette
Isabelle
I
Affinity Petcare, R&D, Pl Xavier Cugat 2, Ed D, Planta 3a, Sant Cugat del Vallès, ES-08174 Barcelona, Spain. ijeusette@affinity-petcare.com
Torre
Celina
C
Salas
Anna
A
Iraculis
Neus
N
Compagnucci
Marco
M
Romano
Victor
V
Kirschvink
Nathalie
N
D000821:Animal Feed; D000818:Animals; D001835:Body Weight; D002371:Cat Diseases / Q000097:blood / Q000178:diet therapy / Q000652:urine; D002415:Cats; D002784:Cholesterol / Q000097:blood; D004041:Dietary Fats / Q000494:pharmacology*; D028441:F2-Isoprostanes / Q000652:urine*; D005260:Female; D044950:Flavanones / Q000494:pharmacology*; D008055:Lipids / Q000097:blood*; D008297:Male; D050177:Overweight / Q000097:blood / Q000178:diet therapy / Q000652:urine / Q000662:veterinary*; D014280:Triglycerides / Q000097:blood
D004041:Dietary Fats; D028441:F2-Isoprostanes; D044950:Flavanones; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol