title: Posterior dynamic stabilization in the treatment of lumbar degenerative disc disease: 2-year follow-up.
abstract: BACKGROUND
  A prospective pilot study was designed to evaluate the role of a posterior dynamic stabilization technique in the surgical treatment of degenerative disc disease. Posterior dynamic stabilization with a hinged screw is a new concept in the surgical treatment of degenerative disc disease of the lumbar spine. The traditional surgical treatment is to apply a fusion procedure. However, numerous reports showed unsatisfactory clinical outcomes even when patients have satisfactory radiological outcomes following fusion procedures.
  
  
  METHODS
  The study included patients who were surgically treated with a dynamic stabilization technique due to painful degenerative disc disease. Clinical and radiological findings for the 20 participating patients were analyzed in a 2-year follow-up study. Preoperative and postoperative data at the 3 (rd), 12 (th) and 24 (th) month were collected for both clinical and radiological outcomes. Statistical analyses between preoperative and postoperative data were performed using the Wilcoxon test.
  
  
  RESULTS
  The clinical outcome measurements (VAS, ODI) showed significant improvement in all postoperative measurements compared to preoperative values. The mean preoperative visual analogue score (VAS, 7.9) and Oswestry Disability Index (ODI 59.2) significantly decreased to 0.8 for VAS and 9.2 for ODI, at 2 years post-operation (p<0.05). The radiological studies showed no significant changes between pre- and postoperative values, in all parameters. There was no mortality or morbidity.
  
  
  CONCLUSIONS
  The results of this pilot study are encouraging. Dynamic stabilization may be an effective technique in the surgical treatment of painful degenerative disc disease. A larger series study, with longer follow-up periods and with control groups is needed to determine the success and safety of posterior dynamic stabilization in the surgical treatment of degenerative disc disease.
authors.affiliation: American Hospital, Neurosurgery Department, Istanbul, Turkey. tuncoktenoglu@gmail.com
authors.forename: T
authors.initials: T
authors.lastname: Oktenoglu
authors.forename: A F
authors.initials: AF
authors.lastname: Ozer
authors.forename: M
authors.initials: M
authors.lastname: Sasani
authors.forename: T
authors.initials: T
authors.lastname: Kaner
authors.forename: N
authors.initials: N
authors.lastname: Canbulat
authors.forename: O
authors.initials: O
authors.lastname: Ercelen
authors.forename: A C
authors.initials: AC
authors.lastname: Sarioglu
mesh_terms: D000328:Adult; D001863:Bone Screws; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000295:instrumentation* / Q000379:methods*; D010865:Pilot Projects; D011446:Prospective Studies; D011859:Radiography; D055009:Spondylosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*