title: Randomized clinical trials regarding management of atherosclerotic renovascular disease.
abstract: Prospective randomized clinical trials that support operative correction of atherosclerotic renovascular disease or catheter-based intervention compared with optimal medical management are lacking. Despite various limitations in study design, each of the five randomized trials reported to date had demonstrated no apparent benefit for renal artery intervention compared with medical management. Three ongoing randomized trials promise to provide additional data and the results of these latter studies will likely dictate future reimbursement through the Centers for Medicare and Medicaid Services.
authors.affiliation: Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1095, USA.
authors.forename: Shawn H
authors.initials: SH
authors.lastname: Fleming
authors.forename: Kimberley J
authors.initials: KJ
authors.lastname: Hansen
mesh_terms: D017130:Angioplasty; D050197:Atherosclerosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012078:Renal Artery Obstruction / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D012107:Research Design; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
chemical_list: D002317:Cardiovascular Agents