title: Molecular genetics, imaging and treatment of oligodendroglial tumours.
abstract: The discovery of a genetic signature of chemosensitivity and prognosis in oligodendroglial tumours prompted a new optimism in glioma management. After more than a decade since the initial reports, where do we stand in the current management of oligodendroglial tumours? This review focuses on the latest molecular genetics, imaging characteristics, and recent trials of treatment paradigms for these tumours.
authors.affiliation: Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK. michael.jenkinson@liv.ac.uk
authors.forename: Michael D
authors.initials: MD
authors.lastname: Jenkinson
authors.forename: Carol
authors.initials: C
authors.lastname: Walker
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Brodbelt
authors.forename: Simone
authors.initials: S
authors.lastname: Wilkins
authors.forename: David
authors.initials: D
authors.lastname: Husband
authors.forename: Brian
authors.initials: B
authors.lastname: Haylock
mesh_terms: D024221:Antineoplastic Protocols / Q000592:standards; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D003131:Combined Modality Therapy / Q000379:methods / Q000639:trends; D003952:Diagnostic Imaging / Q000379:methods / Q000639:trends; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D008967:Molecular Biology / Q000379:methods / Q000639:trends; D009837:Oligodendroglioma / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D011379:Prognosis; D015996:Survival Rate / Q000639:trends