Interferon-gamma-release assays: Better than tuberculin skin testing?
Although the tuberculin skin test has long been the standard for detecting latent tuberculosis infection, it has many limitations. Interferon-gamma-release assays are gaining acceptance as an alternative. In this paper we present cases to illustrate how these new tests can be used and how to interpret the results.
Miranda
Cyndee
C
Department of Infectious Disease, Medicine Institute, G21, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. mirandc@ccf.org
Tomford
J Walton
JW
Gordon
Steven M
SM
D000328:Adult; D000368:Aged; D001769:Blood / Q000276:immunology; D001773:Blood Cells / Q000276:immunology; D002478:Cells, Cultured / Q000276:immunology; D005260:Female; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D007371:Interferon-gamma / Q000032:analysis* / Q000096:biosynthesis*; D055985:Latent Tuberculosis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000276:immunology*
D007371:Interferon-gamma