title: Calculation of energy deposition, photon and neutron production in proton therapy of thyroid gland using MCNPX.
abstract: In this study, the MCNPX code has been used to simulate a proton therapy in thyroid gland, in order to calculate the proton energy deposition in the target region. As well as, we have calculated the photon and neutron production spectra due to proton interactions with the tissue. We have considered all the layers of tissue, from the skin to the thyroid gland, and an incident high energy pencil proton beam. The results of the simulation show that the best proton energy interval, to cover completely the thyroid tissue, is from 42 to 54 MeV, assuming that the thyroid gland has a 14 mm thickness and is located 11.2mm under the skin surface. The most percentage of deposited energy (78%) is related to the 54 MeV proton energy beam. Total photon and neutron production are linear and polynomial second order functions of the proton energy, respectively.
authors.affiliation: S.C. di Fisica Sanitaria, A.O.U. Ospedali Riuniti di Trieste, Trieste, Italy. aa_mowlavi@yahoo.co
authors.forename: Ali Asghar
authors.initials: AA
authors.lastname: Mowlavi
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Fornasie
authors.forename: Mario
authors.initials: M
authors.lastname: de Denaro
mesh_terms: D003198:Computer Simulation; D006801:Humans; D009010:Monte Carlo Method; D061766:Proton Therapy; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D011882:Radiotherapy, High-Energy / Q000379:methods*; D013964:Thyroid Neoplasms / Q000532:radiotherapy*; D011522:Protons
chemical_list: D011522:Protons