[Amyloidosis and end-stage renal disease associated with leprosy].
Renal involvement in leprosy includes glomerulonephritis, amyloidosis and tubulointerstitial nephritis. A 58-year-old man was admitted with complaints of lower limb edema and dyspnea. At admission, nitrogen retention, anemia, hyperkalemia and metabolic acidosis were observed, requiring hemodialysis. The patient had a history of lepromatous leprosy. A renal biopsy was performed that was compatible with amyloidosis. The patient had a stable outcome, but without renal function recovery and remained on regular hemodialysis. Leprosy should be investigated in every patient with renal function loss, particularly in those with cutaneous lesions or other manifestations suggestive of leprosy.
Silva Júnior
Geraldo Bezerra da
GB
Departamento de Medicina Clínica, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE.
Barbosa
Orivaldo Alves
OA
Barros
Roseanne de Moura
Rde M
Carvalho
Priscila Dos Reis
Pdos R
Mendoza
Talita Rodrigues de
TR
Barreto
Dulce Maria Sousa
DM
Barboza
Célio Araújo
CA
Guimarães
Antônio Augusto Carvalho
AA
Daher
Elizabeth de Francesco
Ede F
D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000628:therapy; D007918:Leprosy / Q000150:complications*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods