Effects of d-amphetamine on short- and long-term memory in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rats.
Diverse studies indicate that the attention deficit hyperactivity disorder (ADHD) is associated with alterations in encoding processes, including working or short-term memory. Some ADHD dysfunctional domains are reflected in the spontaneously hypertensive rat (SHR). Here SHR-saline group showed significantly poor STM and LTM relative to SD and WKY saline rats. SD and WKY rats treated with d-amphetamine displayed better STM and LTM, compared to SD-vehicle, WKY-vehicle or SHR-d-amphetamine groups.
Meneses
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A
Department of Pharmacobiology, CINVESTAV, Mexico City, Mexico. ameneses@msn.com
Ponce-Lopez
T
T
Tellez
R
R
Gonzalez
R
R
Castillo
C
C
Gasbarri
A
A
D000661:Amphetamine / Q000494:pharmacology*; D000704:Analysis of Variance; D000818:Animals; D000697:Central Nervous System Stimulants / Q000494:pharmacology; D008297:Male; D057567:Memory, Long-Term / Q000187:drug effects*; D008570:Memory, Short-Term / Q000187:drug effects*; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D017207:Rats, Sprague-Dawley; D013045:Species Specificity
D000697:Central Nervous System Stimulants; D000661:Amphetamine