Spectral loudness summation takes place in the primary auditory cortex.
Auditory functional magnetic resonance imaging (fMRI) was used to assess neural activation in the human auditory brainstem (AB) and cortex (AC) as a function of bandwidth (BW). We recorded brain activation of 22 normal hearing listeners induced by band pass filtered pink noise stimuli with equal sound pressure level of 70 dB SPL. Tested bandwidths were 50, 500, 1,500, 3,000, 6,000, and 8,000 Hz. The center frequency was 4,000 Hz. Categorical loudness scaling had been performed in a silent booth with all of these stimuli. Loudness as a function of bandwidth followed a concave-shaped curve which reflected the influence of spectral loudness summation (SLS) for higher BW and the influence of large amplitude fluctuations for very low BW, which itself could be explained by peak-listening. While neural activation of the AB, as measured by the percent signal change from baseline (PSC), was tuned to the physical BW of the stimuli in a straight linear fashion, the trend of perceived loudness as a function of BW was reflected in several aspects by corresponding neural activation in the primary auditory cortex (PAC). Finally, from the absolute differences of the PSC between PAC and AB, gains in perceived loudness associated with SLS and the effect of large amplitude fluctuations could be predicted with an accuracy of 1-2 dB for the whole group of participants.
Röhl
Markus
M
Medizinische Physik, Universität Oldenburg, Germany. Markus.Roehl@uni-oldenburg.de
Kollmeier
Birger
B
Uppenkamp
Stefan
S
D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D000328:Adult; D001299:Audiometry; D001303:Auditory Cortex / Q000098:blood supply / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology; D001933:Brain Stem / Q000098:blood supply / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008144:Loudness Perception / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D011237:Predictive Value of Tests; D011571:Psychoacoustics; D013057:Spectrum Analysis; D055815:Young Adult
D010100:Oxygen
J Neurophysiol. 2004 Mar;91(3):1282-96
14614108
Hear Res. 1998 Dec;126(1-2):19-27
9872130
Hear Res. 2004 Feb;188(1-2):70-88
14759572
Hear Res. 2005 Apr;202(1-2):47-54
15811698
Neuroimage. 2010 Apr 15;50(3):1202-11
20096790
Neuroimage. 2002 Nov;17(3):1144-61
12414256
Neuroimage. 2010 Apr 15;50(3):1099-108
20053384
Neuroimage. 2007 Apr 1;35(2):709-18
17254802
J Neurophysiol. 2000 Sep;84(3):1588-98
10980029
J Acoust Soc Am. 2008 Feb;123(2):925-34
18247895
Psychiatry Res. 2010 Feb 28;181(2):145-50
20083394
J Acoust Soc Am. 1997 Nov;102(5 Pt 1):2925-34
9373979
Hear Res. 2005 Jun;204(1-2):101-10
15925195
Hum Brain Mapp. 1999;7(3):213-23
10194620
Hear Res. 2006 Dec;222(1-2):125-32
17081712
Hum Brain Mapp. 1997;5(1):18-25
20408207
Neuroimage. 2001 Apr;13(4):669-83
11305896
J Acoust Soc Am. 2007 Sep;122(3):EL69
17927310
Neuron. 2003 Nov 13;40(4):859-69
14622588
Hum Brain Mapp. 2007 Aug;28(8):721-32
17089376
J Cogn Neurosci. 2001 Jan 1;13(1):1-7
11224904
Neuroimage. 2007 Jan 1;34(1):264-73
17049275
Q J Exp Psychol. 1970 Feb;22(1):9-13
5506828
Brain Res. 1973 Feb 28;50(2):275-96
4196192
Hum Brain Mapp. 2008 Jan;29(1):46-56
17318832
Hear Res. 2000 Dec;150(1-2):225-44
11077206
J Exp Psychol Hum Percept Perform. 1990 Nov;16(4):706-27
2148587
Psychol Bull. 1961 May;58:205-17
13747286
Hum Brain Mapp. 1999;7(2):89-97
9950066
Nat Neurosci. 2001 Jun;4(6):633-7
11369945
Hum Brain Mapp. 2007 Aug;28(8):703-20
17080440
Hear Res. 1990 Aug 1;47(1-2):103-38
2228789
Ear Hear. 2009 Apr;30(2):234-7
19194294
Annu Rev Physiol. 2004;66:735-69
14977420
J Acoust Soc Am. 1990 Jun;87(6):2592-605
2373794
J Acoust Soc Am. 2008 May;123(5):2477-9
18529164
J Comp Neurol. 1993 Sep 15;335(3):437-59
7693772
Acta Otolaryngol. 1999 Mar;119(2):154-7
10320066