title: Screening for hazardous alcohol use and depressive symptomatology among HIV-infected patients in Nigeria: prevalence, predictors, and association with adherence.
abstract: Scores from the Alcohol Use Disorders Identification Test (AUDIT) and the Center for Epidemiological Studies Depression Scale (CES-D) administered to both antiretroviral therapy (ART)-experienced and -naive adults in HIV care in Nigeria were evaluated for association with participant characteristics and ART adherence measured by pharmacy records. Participants included 222 ART-experienced and 177 ART-naive adults, of whom 47 (12%) had AUDIT >/=8, 29 (7%) an AUDIT >/=10, 52 (13%) a CES-D >/=16, and 25 (6%) a CES-D >/=21. An elevated AUDIT score was more frequent among ART-naive and men, while disclosure of HIV status to others was associated with lower scores. An elevated CES-D score was more frequent among ART-naive and those with lower educational level, while disclosure of HIV status and choosing to be interviewed in English rather than Hausa was associated with lower scores. An elevated CES-D score was associated with poor adherence.
authors.affiliation: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21218, USA. jfarleymd@aol.com
authors.forename: John
authors.initials: J
authors.lastname: Farley
authors.forename: Erin
authors.initials: E
authors.lastname: Miller
authors.forename: Andrew
authors.initials: A
authors.lastname: Zamani
authors.forename: Vicki
authors.initials: V
authors.lastname: Tepper
authors.forename: Chester
authors.initials: C
authors.lastname: Morris
authors.forename: Modupe
authors.initials: M
authors.lastname: Oyegunle
authors.forename: Maria
authors.initials: M
authors.lastname: Lin
authors.forename: Manhattan
authors.initials: M
authors.lastname: Charurat
authors.forename: William
authors.initials: W
authors.lastname: Blattner
mesh_terms: D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003863:Depression / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D055118:Medication Adherence; D009549:Nigeria / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents
references.citation: Int J Psychiatry Med. 2008;38(1):43-51
references.pmid: 18624016
references.citation: J Acquir Immune Defic Syndr. 2007 Aug 15;45(5):560-3
references.pmid: 17558333
references.citation: Psychol Rep. 1991 Dec;69(3 Pt 2):1179-85
references.pmid: 1792288
references.citation: J Acquir Immune Defic Syndr. 2008 Aug 1;48(4):468-75
references.pmid: 18614918
references.citation: AIDS Care. 2008 Jul;20(6):741-5
references.pmid: 18576177
references.citation: PLoS One. 2010 May 11;5(5):e10584
references.pmid: 20485670
references.citation: Int J Geriatr Psychiatry. 1997 Apr;12(4):436-46
references.pmid: 9178047
references.citation: Drug Alcohol Depend. 1992 Jun;30(2):163-7
references.pmid: 1633755
references.citation: J Acquir Immune Defic Syndr. 2008 Mar 1;47(3):384-90
references.pmid: 18091609
references.citation: AIDS Patient Care STDS. 2008 Feb;22(2):147-58
references.pmid: 18260806
references.citation: Cent Afr J Med. 1993 Feb;39(2):26-32
references.pmid: 8261500
references.citation: AIDS Behav. 2009 Jun;13 Suppl 1:82-91
references.pmid: 19301113
references.citation: Drugs. 2006;66(6):769-89
references.pmid: 16706551
references.citation: Curr HIV/AIDS Rep. 2008 Nov;5(4):163-71
references.pmid: 18838056
references.citation: JAMA. 2006 Aug 9;296(6):679-90
references.pmid: 16896111
references.citation: Addiction. 1993 Jun;88(6):791-804
references.pmid: 8329970
references.citation: Alcohol Alcohol. 2005 Nov-Dec;40(6):575-7
references.pmid: 16115823
references.citation: BMC Public Health. 2008 Jul 30;8:265
references.pmid: 18667066
references.citation: PLoS Med. 2007 Oct 16;4(10):e298
references.pmid: 17941716
references.citation: AIDS Behav. 2006 Jul;10(4 Suppl):S105-11
references.pmid: 16802195
references.citation: HIV Med. 2007 Mar;8(2):92-5
references.pmid: 17352765
references.citation: AIDS Res Hum Retroviruses. 2008 Aug;24(8):1031-5
references.pmid: 18724803
references.citation: Arch Intern Med. 1997 Feb 24;157(4):449-54
references.pmid: 9046897
references.citation: Addiction. 1995 Oct;90(10):1349-56
references.pmid: 8616463
references.citation: J Psychosom Res. 2006 Oct;61(4):479-84
references.pmid: 17011355
references.citation: J Stud Alcohol. 1995 Jul;56(4):423-32
references.pmid: 7674678
references.citation: J Acquir Immune Defic Syndr. 2009 Apr 1;50(4):397-402
references.pmid: 19214119
references.citation: J Stud Alcohol. 2002 Mar;63(2):179-86
references.pmid: 12033694
references.citation: Eur J Clin Pharmacol. 2007 Dec;63(12):1115-21
references.pmid: 17882408
references.citation: Int J Epidemiol. 2000 Oct;29(5):911-5
references.pmid: 11034977
references.citation: Int J Epidemiol. 2009 Jun;38(3):746-56
references.pmid: 19223334
references.citation: J Acquir Immune Defic Syndr. 2009 Oct 1;52(2):180-202
references.pmid: 19668086
references.citation: East Afr Med J. 2004 Nov;81(11):594-8
references.pmid: 15868970
references.citation: Prev Sci. 2007 Jun;8(2):141-51
references.pmid: 17265194
references.citation: J Nerv Ment Dis. 2000 Oct;188(10):662-70
references.pmid: 11048815
references.citation: PLoS Med. 2008 May 20;5(5):e109
references.pmid: 18494555
references.citation: AIDS. 2007 May 31;21(9):1175-83
references.pmid: 17502728
references.citation: J Acquir Immune Defic Syndr. 2005 Apr 1;38(4):432-8
references.pmid: 15764960