Linear childhood discoid lupus erythematosus following the lines of Blaschko: successfully treated with topical tacrolimus.
The linear arrangement of discoid lupus erythematosus is uncommon. Here, we report a 6-year-old Japanese girl with linear discoid lupus erythematosus following the lines of Blaschko on her face and neck. Topical tacrolimus treatment improved the eruptions. The present case also indicated the important role of epidermal and dermal cells as well as immune cells in the pathogenesis of cutaneous lupus erythematodes.
Kawachi
Yasuhiro
Y
Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan. hukyasuhir@md.tsukuba.ac.jp
Taguchi
Shijima
S
Fujisawa
Yasuhiro
Y
Furuta
Junichi
J
Nakamura
Yasuhiro
Y
Ishii
Yoshiyuki
Y
Otsuka
Fujio
F
D000287:Administration, Topical; D001706:Biopsy; D002648:Child; D005145:Face / Q000473:pathology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy* / Q000473:pathology*; D016559:Tacrolimus / Q000008:administration & dosage*
D007166:Immunosuppressive Agents; D016559:Tacrolimus