Leukocyte adhesion deficiency type 1 presenting with recurrent pyoderma gangrenosum and flaccid scarring.
We report an 11-year-old boy with a longstanding history of recurrent pyoderma gangrenosum and abnormal wound healing who eventually developed a fatal invasive fungal infection. This article emphasizes the importance to consider leukocyte adhesion deficiency type 1 in the differential diagnosis of patients with recurrent skin ulcers.
Hinze
Claas H
CH
Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA. claas.hinze@gmail.com
Lucky
Anne W
AW
Bove
Kevin E
KE
Marsh
Rebecca A
RA
Bleesing
Jack H
JH
Passo
Murray H
MH
D001706:Biopsy; D002648:Child; D002921:Cicatrix / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D018370:Leukocyte-Adhesion Deficiency Syndrome / Q000150:complications / Q000276:immunology / Q000473:pathology; D008297:Male; D017511:Pyoderma Gangrenosum / Q000150:complications* / Q000276:immunology / Q000473:pathology*; D012008:Recurrence; D012867:Skin / Q000276:immunology / Q000473:pathology