title: The nature of naming errors in primary progressive aphasia versus acute post-stroke aphasia.
abstract: OBJECTIVE
  To compare the distribution of error types across subgroups of primary progressive aphasia and poststroke aphasia in different vascular locations.
  
  
  METHODS
  We analyzed naming errors in 49 individuals with acute left hemisphere ischemic stroke and 55 individuals with three variants of primary progressive aphasia. Location of atrophy or ischemic stroke was characterized using MRI.
  
  
  RESULTS
  We found that distribution of error types was very similar across all subgroups, irrespective of the site or etiology of the lesion. The only significant difference across groups was the percentage of circumlocutions (F(7, 96) = 3.02, p = .005). Circumlocution errors were highest among logopenic variant PPA (24%) and semantic variant PPA (24%). Semantic coordinate errors were common in all groups, probably because they can arise from disruption of different cognitive processes underlying naming and, therefore, from different locations of brain damage.
  
  
  CONCLUSIONS
  Semantic errors are common among all types of primary progressive aphasia and poststroke aphasia, and the type of error depends in part on the location of damage.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
authors.forename: Maggi A
authors.initials: MA
authors.lastname: Budd
authors.forename: Kathleen
authors.initials: K
authors.lastname: Kortte
authors.forename: Lauren
authors.initials: L
authors.lastname: Cloutman
authors.forename: Melissa
authors.initials: M
authors.lastname: Newhart
authors.forename: Rebecca F
authors.initials: RF
authors.lastname: Gottesman
authors.forename: Cameron
authors.initials: C
authors.lastname: Davis
authors.forename: Jennifer
authors.initials: J
authors.lastname: Heidler-Gary
authors.forename: Margaret W
authors.initials: MW
authors.lastname: Seay
authors.forename: Argye E
authors.initials: AE
authors.lastname: Hillis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001037:Aphasia / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D018888:Aphasia, Primary Progressive / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007806:Language Disorders / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D012660:Semantics; D013060:Speech; D020521:Stroke / Q000150:complications* / Q000473:pathology; D014705:Verbal Behavior; D014825:Vocabulary; D055815:Young Adult
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