title: Catatonia associated with initiating paliperidone treatment.
abstract: We present a case of catatonia, which occurred shortly after starting a new antipsychotic, paliperidone, an active metabolite of risperidone. Catatonia may be caused by a variety of conditions, including metabolic, neurologic, psychiatric and toxic processes. Interestingly, risperidone, which has been thought to cause several cases of catatonia, has also been recommended as a potential treatment. We discuss potential mechanisms for causes of drug-induced catatonia as well as potential treatment options.
authors.affiliation: Oregon Health & Science University, Department of Emergency Medicine, Oregon Poison Control Center, Portland VA.
authors.forename: Nathanael J
authors.initials: NJ
authors.lastname: McKeown
authors.forename: James H
authors.initials: JH
authors.lastname: Bryan
authors.forename: B Zane
authors.initials: BZ
authors.lastname: Horowitz
references.citation: J Clin Psychopharmacol. 1983 Dec;3(6):338-42
references.pmid: 6139391
references.citation: Can J Psychiatry. 2005 Mar;50(4):241-2
references.pmid: 15898466
references.citation: Int J Neuropsychopharmacol. 2001 Sep;4(3):251-7
references.pmid: 11602030
references.citation: Drugs Today (Barc). 2005 Sep;41(9):599-607
references.pmid: 16341291
references.citation: J Neuropsychiatry Clin Neurosci. 2001 Spring;13(2):303-4
references.pmid: 11449040
references.citation: Clin Neuropharmacol. 2001 Jul-Aug;24(4):228-31
references.pmid: 11479394
references.citation: Pharmacopsychiatry. 2001 Jan;34(1):25-6
references.pmid: 11229618
references.citation: Psychiatry Clin Neurosci. 1999 Feb;53(1):63-6
references.pmid: 10201286
references.citation: Am J Psychiatry. 2003 Jul;160(7):1233-41
references.pmid: 12832234
references.citation: Med Lett Drugs Ther. 2007 Mar 12;49(1256):21-3
references.pmid: 17351558
references.citation: Clin Pharmacol Ther. 1981 Aug;30(2):239-45
references.pmid: 7249508
references.citation: Arch Gen Psychiatry. 1996 Jan;53(1):82-3
references.pmid: 8540780
references.citation: J Dev Behav Pediatr. 2006 Aug;27(4):369
references.pmid: 16906015
references.citation: Acta Psychiatr Scand. 1999 Mar;99(3):223-4; discussion 224-6
references.pmid: 10100918