Chronic shedders as reservoir for nosocomial transmission of norovirus.
Norovirus (NoV) infection in immunocompromised patients may lead to prolonged norovirus shedding. Here, we demonstrate the involvement of three chronic shedders in hospital outbreaks. Combined epidemiological and molecular evidence suggests that in one case, NoV transmission occurred at least 17 days after the first diagnosis.
Sukhrie
Faizel H A
FH
Laboratory for Infectious Diseases and Perinatal Screening, National Institute for Public Health and the Environment, Bilthoven, Netherlands. faizel.sukhrie@rivm.nl
Siebenga
J Joukje
JJ
Beersma
Matthias F C
MF
Koopmans
Marion
M
D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D003428:Cross Infection / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D006801:Humans; D016867:Immunocompromised Host; D017720:Molecular Epidemiology; D029322:Norovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017201:Virus Shedding
J Infect Dis. 2008 Oct 1;198(7):994-1001
18774885
J Hosp Infect. 2009 Mar;71(3):199-205
19147255
Comput Appl Biosci. 1994 Sep;10(5):569-70
7828077
J Gen Virol. 2004 Jan;85(Pt 1):79-87
14718622
J Infect Dis. 2009 Sep 1;200(5):802-12
19627248
Emerg Infect Dis. 2007 Jan;13(1):144-6
17370531
J Clin Microbiol. 2008 Mar;46(3):947-53
18216210
Curr Opin Infect Dis. 2008 Oct;21(5):544-52
18725806
J Med Virol. 2009 Jul;81(7):1298-304
19475614
Curr Opin Infect Dis. 2006 Oct;19(5):467-74
16940871