title: Excitation function for deuteron induced nuclear reactions on natural ytterbium for production of high specific activity 177g Lu in no-carrier-added form for metabolic radiotherapy.
abstract: Deuteron-induced nuclear reactions for generation of no-carrier-added Lu radionuclides were investigated using the stacked-foil activation technique on natural Yb targets at energies up to E(d)=18.18 MeV. Excitation functions of the reactions (nat)Yb(d,xn)(169,170,171,172,173,174g,174m,176m,177g)Lu and (nat)Yb(d,pxn)(169,175,177)Yb have been measured, among them three ((169)Lu, (174m)Lu and (176m)Lu) are reported for the first time. The upper limit of the contamination from the long-lived metastable level (177m)Lu was evaluated too. Thick-target yields for all investigated radionuclides are calculated.
authors.affiliation: LASA, Università degli Studi di Milano and INFN-Milano, via F.lli Cervi 201, I-20090 Segrate (MI), Italy. simone.manenti@mi.infn.it
authors.forename: Simone
authors.initials: S
authors.lastname: Manenti
authors.forename: Flavia
authors.initials: F
authors.lastname: Groppi
authors.forename: Andrea
authors.initials: A
authors.lastname: Gandini
authors.forename: Luigi
authors.initials: L
authors.lastname: Gini
authors.forename: Kamel
authors.initials: K
authors.lastname: Abbas
authors.forename: Uwe
authors.initials: U
authors.lastname: Holzwarth
authors.forename: Federica
authors.initials: F
authors.lastname: Simonelli
authors.forename: Mauro
authors.initials: M
authors.lastname: Bonardi
mesh_terms: D003903:Deuterium / Q000737:chemistry; D006801:Humans; D008187:Lutetium / Q000737:chemistry*; D009683:Nuclear Medicine / Q000379:methods; D011868:Radioisotopes / Q000737:chemistry*; D015018:Ytterbium / Q000737:chemistry*
chemical_list: D011868:Radioisotopes; D008187:Lutetium; D003903:Deuterium; D015018:Ytterbium