title: Plant protein-protein interaction network and interactome.
abstract: Protein-protein interaction network represents an important aspect of systems biology. The understanding of the plant protein-protein interaction network and interactome will provide crucial insights into the regulation of plant developmental, physiological, and pathological processes. In this review, we will first define the concept of plant interactome and the protein-protein interaction network. The significance of the plant interactome study will be discussed. We will then compare the pros and cons for different strategies for interactome mapping including yeast two-hybrid system (Y2H), affinity purification mass spectrometry (AP-MS), bimolecular fluorescence complementation (BiFC), and in silico prediction. The application of these platforms on specific plant biology questions will be further discussed. The recent advancements revealed the great potential for plant protein-protein interaction network and interactome to elucidate molecular mechanisms for signal transduction, stress responses, cell cycle control, pattern formation, and others. Mapping the plant interactome in model species will provide important guideline for the future study of plant biology.
authors.affiliation: Department of Plant Pathology and Microbiology, Texas A&M University, College Station, TX 77843, USA.
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Gao
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Yuan
references.citation: Nat Rev Genet. 2007 Sep;8(9):699-710
references.pmid: 17703239
references.citation: Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5187-92
references.pmid: 9560251
references.citation: Proteomics. 2002 Jun;2(6):611-23
references.pmid: 12112840
references.citation: Plant Physiol. 2007 Dec;145(4):1090-9
references.pmid: 18056859
references.citation: Nature. 2003 Mar 13;422(6928):208-15
references.pmid: 12634794
references.citation: BMC Bioinformatics. 2008;9 Suppl 1:S20
references.pmid: 18315852
references.citation: Trends Plant Sci. 2008 Apr;13(4):183-91
references.pmid: 18329319
references.citation: Annu Rev Biophys. 2008;37:465-87
references.pmid: 18573091
references.citation: Nature. 2002 May 23;417(6887):399-403
references.pmid: 12000970
references.citation: Science. 2004 Jan 23;303(5657):540-3
references.pmid: 14704431
references.citation: Plant J. 2005 Mar;41(5):767-78
references.pmid: 15703063
references.citation: J Am Chem Soc. 2005 Jan 12;127(1):146-57
references.pmid: 15631464
references.citation: Trends Plant Sci. 2008 Apr;13(4):165-71
references.pmid: 18329321
references.citation: J Exp Bot. 2008;59(4):965-72
references.pmid: 18349053
references.citation: Curr Opin Chem Biol. 2003 Oct;7(5):557-62
references.pmid: 14580558
references.citation: Mol Biol Rep. 2008 Sep;35(3):337-43
references.pmid: 17564813
references.citation: Curr Protoc Cell Biol. 2006 Jan;Chapter 21:Unit 21.3
references.pmid: 18228482
references.citation: Methods. 2008 Jul;45(3):196-206
references.pmid: 18586107
references.citation: Mol Cell Proteomics. 2007 Jul;6(7):1226-38
references.pmid: 17426018
references.citation: Plant J. 2009 Mar;57(5):932-44
references.pmid: 19000159
references.citation: Proteomics. 2007 Aug;7(16):2947-62
references.pmid: 17654459
references.citation: Nat Genet. 2006 Aug;38(8):896-903
references.pmid: 16845399
references.citation: Plant Physiol. 2007 Oct;145(2):317-29
references.pmid: 17675552
references.citation: Nat Methods. 2006 Dec;3(12):1013-9
references.pmid: 17060908
references.citation: Genome Res. 2001 Dec;11(12):2120-6
references.pmid: 11731503
references.citation: Trends Plant Sci. 2009 Feb;14(2):59-63
references.pmid: 19150604
references.citation: J Physiol. 2005 Feb 15;563(Pt 1):11-21
references.pmid: 15611014
references.citation: Mass Spectrom Rev. 2004 Sep-Oct;23(5):350-67
references.pmid: 15264234
references.citation: Cell. 2005 Sep 23;122(6):957-68
references.pmid: 16169070
references.citation: Plant Physiol. 2007 Feb;143(2):670-83
references.pmid: 17172288
references.citation: PLoS Biol. 2008 Mar 4;6(3):e68
references.pmid: 18318603
references.citation: Adv Biochem Eng Biotechnol. 2005;95:1-15
references.pmid: 16080263
references.citation: Trends Plant Sci. 2008 Oct;13(10):517-20
references.pmid: 18771946
references.citation: Nucleic Acids Res. 2008 Jan;36(Database issue):D999-1008
references.pmid: 17962307
references.citation: Plant Mol Biol. 2002 Dec;50(6):855-70
references.pmid: 12516858
references.citation: Nature. 2000 Feb 10;403(6770):623-7
references.pmid: 10688190
references.citation: Plant J. 2006 Apr;46(1):1-13
references.pmid: 16553892
references.citation: Nat Methods. 2006 Aug;3(8):597-600
references.pmid: 16862132
references.citation: Plant J. 2008 Nov;56(3):505-16
references.pmid: 18643980
references.citation: Biotechniques. 2006 Jan;40(1):61-6
references.pmid: 16454041
references.citation: EMBO J. 1999 Oct 1;18(19):5370-9
references.pmid: 10508169
references.citation: Nat Genet. 2006 Mar;38(3):285-93
references.pmid: 16501559
references.citation: Plant J. 2004 Nov;40(3):419-27
references.pmid: 15469499
references.citation: Science. 2001 Dec 14;294(5550):2364-8
references.pmid: 11743205
references.citation: Nature. 2002 Jan 10;415(6868):180-3
references.pmid: 11805837
references.citation: Mol Syst Biol. 2007;3:88
references.pmid: 17353930
references.citation: J Exp Bot. 2006;57(7):1563-71
references.pmid: 16551681
references.citation: J Proteome Res. 2008 Sep;7(9):3649-60
references.pmid: 18642946
references.citation: Trends Plant Sci. 2008 Aug;13(8):421-9
references.pmid: 18632303
references.citation: Nature. 2006 Mar 30;440(7084):637-43
references.pmid: 16554755
references.citation: Genome Biol. 2004;5(12):R96
references.pmid: 15575970
references.citation: Planta. 2006 Sep;224(4):771-81
references.pmid: 16575597
references.citation: Cell. 2002 Jul 26;110(2):163-75
references.pmid: 12150925
references.citation: Methods. 2007 Jul;42(3):298-305
references.pmid: 17532517
references.citation: Plant Physiol. 2005 Jun;138(2):558-9
references.pmid: 15955914
references.citation: Nat Rev Mol Cell Biol. 2007 Aug;8(8):645-54
references.pmid: 17593931
references.citation: J Proteomics. 2009 Apr 13;72(3):285-314
references.pmid: 19367730
references.citation: Nature. 2002 Jan 10;415(6868):141-7
references.pmid: 11805826
references.citation: Nature. 2006 Mar 30;440(7084):631-6
references.pmid: 16429126
references.citation: Plant Physiol. 2009 Mar;149(3):1478-92
references.pmid: 19109415
references.citation: Nature. 1989 Jul 20;340(6230):245-6
references.pmid: 2547163
references.citation: Nat Biotechnol. 2006 Apr;24(4):427-33
references.pmid: 16601728
references.citation: Plant J. 2004 Apr;38(1):172-81
references.pmid: 15053770
references.citation: Plant Mol Biol. 2007 Mar;63(5):703-18
references.pmid: 17211514
references.citation: Methods Enzymol. 2001;332:277-300
references.pmid: 11305104
references.citation: Annu Rev Genet. 1997;31:663-704
references.pmid: 9442911
references.citation: Science. 2004 Feb 6;303(5659):808-13
references.pmid: 14764870
references.citation: Nat Biotechnol. 2003 Jan;21(1):89-92
references.pmid: 12483225
references.citation: Microbiol Rev. 1995 Mar;59(1):94-123
references.pmid: 7708014
references.citation: Proteomics. 2006 Oct;6(20):5529-48
references.pmid: 16991197
references.citation: Curr Biol. 1998 Oct 8;8(20):1121-4
references.pmid: 9778531
references.citation: Proteomics. 2008 Feb;8(4):893-908
references.pmid: 18210371
references.citation: Plant J. 2004 Oct;40(1):22-34
references.pmid: 15361138
references.citation: Mol Cell Proteomics. 2007 Apr;6(4):601-10
references.pmid: 17272265
references.citation: Nat Genet. 2005 Oct;37(10):1147-52
references.pmid: 16155567
references.citation: Proteomics. 2004 Dec;4(12):3845-54
references.pmid: 15540166
references.citation: Science. 2003 Dec 5;302(5651):1727-36
references.pmid: 14605208
references.citation: Plant Cell. 2005 May;17(5):1424-33
references.pmid: 15805477
references.citation: BMC Genomics. 2008 May 14;9:220
references.pmid: 18479511
references.citation: J Proteome Res. 2008 Oct;7(10):4209-10
references.pmid: 18785769
references.citation: Nature. 2005 Oct 20;437(7062):1173-8
references.pmid: 16189514
references.citation: Nat Rev Genet. 2007 Jun;8(6):437-49
references.pmid: 17510664
references.citation: Mol Cell. 2002 Apr;9(4):789-98
references.pmid: 11983170
references.citation: Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4569-74
references.pmid: 11283351
references.citation: Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4945-50
references.pmid: 12684538
references.citation: Plant J. 2008 Aug;55(3):491-503
references.pmid: 18433439