title: Tolerance of benznidazole in treatment of Chagas' disease in adults.
abstract: Chagas' disease is an emerging public health problem in areas where the disease is not endemic. Treatment with benznidazole has shown efficacy in the acute stage of the disease, but its efficacy in the chronic stage remains controversial, and unwanted side effects are more frequent and severe in adults than in children. This study describes the profile of side effects of benznidazole in a cohort of Trypanosoma cruzi-infected patients in a European country.
authors.affiliation: Tropical Diseases Section, Barcelona Centre for International Health Research, Hospital Clinic, Villarroel 170, Barcelona, Spain. mpinazo@clinic.ub.es
authors.forename: María-Jesús
authors.initials: MJ
authors.lastname: Pinazo
authors.forename: José
authors.initials: J
authors.lastname: Muñoz
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Posada
authors.forename: Paulo
authors.initials: P
authors.lastname: López-Chejade
authors.forename: Montserrat
authors.initials: M
authors.lastname: Gállego
authors.forename: Edgar
authors.initials: E
authors.lastname: Ayala
authors.forename: Elena
authors.initials: E
authors.lastname: del Cacho
authors.forename: Dolors
authors.initials: D
authors.lastname: Soy
authors.forename: Joaquim
authors.initials: J
authors.lastname: Gascon
mesh_terms: D000293:Adolescent; D000328:Adult; D014355:Chagas Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009593:Nitroimidazoles / Q000009:adverse effects* / Q000627:therapeutic use*; D014344:Trypanocidal Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole
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