title: On the relationship between structure and reaction rate in olefin ring-closing metathesis.
abstract: In the RCM reactions of a series of simple α,ω-dienes, the relative order of reactivity has been unambiguously determined showing that cyclohexene forms faster than cyclopentene or cycloheptene. 1,5-Hexadiene inhibits the RCM of 1,7-octadiene; 1,5-hexadiene cannot progress to the RCM product (cyclobutene) but forms an unexpectedly stable cyclic η(2)-complex.
authors.affiliation: AstraZeneca Global Research and Development, Silk Road Business Park, Charter Way, Macclesfield, SK10 2NA, UK.
authors.forename: Ian W
authors.initials: IW
authors.lastname: Ashworth
authors.forename: Davide
authors.initials: D
authors.lastname: Carboni
authors.forename: Ian H
authors.initials: IH
authors.lastname: Hillier
authors.forename: David J
authors.initials: DJ
authors.lastname: Nelson
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Percy
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Rinaudo
authors.forename: Mark A
authors.initials: MA
authors.lastname: Vincent
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D003500:Cyclization; D053138:Cyclohexenes / Q000737:chemistry; D003517:Cyclopentanes / Q000737:chemistry; D007700:Kinetics; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D053138:Cyclohexenes; D003517:Cyclopentanes; C052568:cyclohexene