title: Study of intra-abdominal fat distribution in sigmoid colon cancer in Japanese patients by use of MDCT data.
abstract: To assess the relationship between intra-abdominal fat and sigmoid colon cancer, we investigated the intra-abdominal fat distribution in 172 examples of sigmoid colon cancer and 767 examples of various other pathologies by using data from multidetector-row computed tomography. One significant finding was that the intra-abdominal fat area in sigmoid colon cancer presents a small secondary peak in the pelvis on the profile of the intra-abdominal fat, which we called the pelvic sub-peak. The presence or absence of the pelvic sub-peak was determined based on the sub-peak ratio, which was calculated by dividing the maximum peak by the sub-peak value on the profile of the intra-abdominal fat area. The pelvic sub-peak was defined as having a sub-peak ratio >or=0.1. The pelvic sub-peak frequency was higher for all male patients than for female patients. The frequency of the pelvic sub-peak in sigmoid colon cancer was 77.5% (79/102) for men and 50.0% (35/70) for women. Among both men and women, frequencies of the pelvic sub-peak were significantly higher in patients with sigmoid colon cancer than in non-tumor cases (P < 0.001). Furthermore, the frequency of the pelvic sub-peak was almost the same in sigmoid colon cancer as in rectal cancer. No causal relationship between sigmoid colon cancer and a pelvic sub-peak could be confirmed in the present study; however, patients with sigmoid colon cancer tended to exhibit a unique pattern of fat accumulation.
authors.affiliation: School of Radiological Technology, Gunma Prefectural College of Health Sciences, Maebashi, Gunma, Japan. togura@gchs.ac.jp
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ogura
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Tachikawa
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Nishimura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suda
authors.forename: Younosuke
authors.initials: Y
authors.lastname: Shimomura
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Oya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kono
mesh_terms: D050153:Abdominal Fat / Q000378:metabolism*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging; D012811:Sigmoid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism*; D014057:Tomography, X-Ray Computed; D055815:Young Adult
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