title: The new Powerplex® ESX17 and ESI17 kits in paternity and maternity analyses involving people from Africa--including allele frequencies for three African populations.
abstract: Paternity and maternity investigations in immigration procedures are frequently done in Germany. Since mostly only one parent and one or more children are investigated, the occurrence of possible mutational events has to be interpreted with great care and the analysis of as many STRs as possible is recommended. The new Powerplex® ESX17 and Powerplex® ESI17 kits from Promega comprising both eleven established STRs and additionally the loci D1S1656, D2S441, D10S1248, D12S391, and D22S1045 (in different order) are potential tools in such paternity or maternity analyses, but only few allele frequency data for the five new loci exist. Here, we provide allele frequencies for the five additional STRs from three different populations from Africa. In addition, we present two maternity cases and one paternity case in which a clear inclusion or exclusion of the alleged parent could only be achieved by the additional application of the new Powerplex® ESX17 kit.
authors.affiliation: Institute of Legal Medicine, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany. micaela.poetsch@uk-essen.de
authors.forename: Micaela
authors.initials: M
authors.lastname: Poetsch
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Ergin
authors.forename: Katharina
authors.initials: K
authors.lastname: Bayer
authors.forename: Daniela
authors.initials: D
authors.lastname: El-Mostaqim
authors.forename: Noel
authors.initials: N
authors.lastname: Rakotomavo
authors.forename: Edmund N L
authors.initials: EN
authors.lastname: Browne
authors.forename: Christian
authors.initials: C
authors.lastname: Timmann
authors.forename: Rolf D
authors.initials: RD
authors.lastname: Horstmann
authors.forename: Thorsten
authors.initials: T
authors.lastname: Schwark
authors.forename: Nicole
authors.initials: N
authors.lastname: von Wurmb-Schwark
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016172:DNA Fingerprinting; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D005869:Ghana; D006801:Humans; D008270:Madagascar; D008297:Male; D008875:Middle Aged; D009018:Morocco; D010334:Paternity; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D055815:Young Adult
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