[Clinical significance of food antigens blotting capacity by patients with irritable bowel syndrome].
53 patients suffered from IBS (according to Rome III criteria) were included to the study with solid-phase immune-enzyme detection of the ovalbumin blood level after consumption of egg whites. Patient complaints and quality of life were assessed. The same blood samples were tested for content of the total IgE and specific to food IgE (13 food allergens); specific to food IgG (24 food allergens). The abnormal intestinal permeability was found in 38% IBS patients, also the degree of abdominal pain was significantly higher and quality of life was lower in this patients. The abnormal intestinal permeability was found more frequently in IBS-C patients High levels of IgE and IgG were detected in a few IBS patients.
Pilipenko
V I
VI
Burliaeva
E A
EA
Isakov
V A
VA
Morozov
S V
SV
Shakhovskaia
A K
AK
Zorin
S M
SM
Gmoshinskiĭ
I V
IV
Mazo
V K
VK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000941:Antigens / Q000276:immunology* / Q000378:metabolism; D005260:Female; D005502:Food; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000276:immunology / Q000503:physiopathology; D043183:Irritable Bowel Syndrome / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010539:Permeability
D000941:Antigens; D007074:Immunoglobulin G; D007073:Immunoglobulin E