Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1.
This study investigates the association of rheumatoid arthritis-associated single nucleotide polymorphisms in endometriosis. We found an association of CCL21 (rs2812378) and HLA-DRB1 (rs660895) with moderate to severe endometriosis.
Sundqvist
Johanna
J
Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet/Karolinska University Hospital, Stockholm, Sweden.
Falconer
Henrik
H
Seddighzadeh
Maria
M
Vodolazkaia
Alexandra
A
Fassbender
Amelie
A
Kyama
Cleophas
C
Bokor
Attila
A
Stephansson
Olof
O
Padyukov
Leonid
L
Gemzell-Danielsson
Kristina
K
D'Hooghe
Thomas M
TM
D000328:Adult; D001327:Autoimmune Diseases / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D054421:Chemokine CCL21 / Q000235:genetics*; D004715:Endometriosis / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D012720:Severity of Illness Index
C515478:CCL21 protein, human; D054421:Chemokine CCL21; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains