The impact of maternal age on fetal death: does length of gestation matter?
OBJECTIVE
The objective of the investigation was to study the association of fetal death with maternal age by length of gestation.


METHODS
This was a population study including all ongoing pregnancies after 16 weeks of gestation in Norway during the period 1967-2006 (n = 2,182,756).


RESULTS
The risk of fetal death was 1.4 times higher in women 40-44 years old than in women aged 20-24 years in midpregnancy but 2.8 times higher at term. In term pregnancies the relative importance of maternal age increased by additional pregnancy weeks. In gestational weeks 42-43, the crude risk was 5.1 times higher in mothers 40 years old or older. In the recent period, the elevated risk of fetal death in elderly mothers at term has been attenuated.


CONCLUSIONS
Women 40 years old or older had the highest risk of fetal death throughout pregnancy, particularly in term and postterm pregnancies. Improved obstetric care may explain the attenuation of risk associated with age in recent time.
Haavaldsen
Camilla
C
Department of Gynecology and Obstetrics, Akershus University Hospital, and Medical Faculty Division, University of Oslo, Oslo, Norway. marit.camilla.haavaldsen@ahus.no
Sarfraz
Aahshi A
AA
Samuelsen
Sven O
SO
Eskild
Anne
A
D000328:Adult; D015331:Cohort Studies; D005260:Female; D005313:Fetal Death / Q000453:epidemiology* / Q000209:etiology; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008423:Maternal Age; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D011247:Pregnancy; D011273:Pregnancy, Prolonged; D015995:Prevalence; D012042:Registries; D018570:Risk Assessment; D047929:Term Birth; D013997:Time Factors; D055815:Young Adult