Peroxisome proliferator-activated receptor gamma and early folliculogenesis during an acute hyperandrogenism condition.
Acute hyperandrogenism decreases serum P levels and induces early apoptosis of antral follicles by a mechanism mediated by the peroxisome proliferator-activated receptor gamma system and independent of the steroidogenic acute regulator protein.
Faut
Monica
M
Laboratorio de Fisio-patología Ovárica, Centro de Estudios Farmacológicos y Botánicos, Buenos Aires, Argentina.
Elia
Evelin Mariel
EM
Parborell
Fernanda
F
Cugnata
Noelia Melina
NM
Tesone
Marta
M
Motta
Alicia Beatriz
AB
D000208:Acute Disease; D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D003687:Dehydroepiandrosterone / Q000494:pharmacology; D005260:Female; D015870:Gene Expression / Q000187:drug effects; D017588:Hyperandrogenism / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D006080:Ovarian Follicle / Q000187:drug effects* / Q000473:pathology / Q000502:physiology*; D047495:PPAR gamma / Q000235:genetics / Q000378:metabolism*; D010750:Phosphoproteins / Q000235:genetics / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012102:Reproductive Control Agents / Q000494:pharmacology; D000098682:Steroidogenic Acute Regulatory Protein
D006063:Chorionic Gonadotropin; D047495:PPAR gamma; D010750:Phosphoproteins; D012102:Reproductive Control Agents; D000098682:Steroidogenic Acute Regulatory Protein; D003687:Dehydroepiandrosterone