Asymmetric Cu(II) catalyses for cycloaddition reactions based on π-cation or n-cation interactions.
The rational design of small but highly functional artificial catalysts is very important for practical organic synthesis. Asymmetric Lewis acid catalyses with non-covalent secondary interactions have been developed for enantioselective reactions. This tutorial review describes the concept, design and examples of asymmetric Cu(ii) catalyses for cycloaddition reactions based on intramolecular π-cation or n-cation interactions between the copper(ii) cation and auxiliary Lewis basic sites of the chiral ligands.
Sakakura
Akira
A
EcoTopia Science Institute, Nagoya University, Japan.
Ishihara
Kazuaki
K
D002384:Catalysis; D002412:Cations / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D013237:Stereoisomerism
D002412:Cations; D003300:Copper