title: Dosage compensation and the global re-balancing of aneuploid genomes.
abstract: Diploid genomes are exquisitely balanced systems of gene expression. The dosage-compensation systems that evolved along with monosomic sex chromosomes exemplify the intricacies of compensating for differences in gene copy number by transcriptional regulation.
authors.affiliation: Adolf-Butenandt-Institute and Centre for Integrated Protein Science (CiPSM), Ludwig-Maximilians-University, Schillerstrasse 44, 80336 Munich, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Prestel
authors.forename: Christian
authors.initials: C
authors.lastname: Feller
authors.forename: Peter B
authors.initials: PB
authors.lastname: Becker
mesh_terms: D000782:Aneuploidy; D000818:Animals; D004303:Dosage Compensation, Genetic; D005260:Female; D018628:Gene Dosage; D005786:Gene Expression Regulation; D016678:Genome / Q000235:genetics*; D006801:Humans; D008297:Male; D012730:Sex Chromosomes
references.citation: Oncogene. 2007 Aug 13;26(37):5385-94
references.pmid: 17694080
references.citation: Mol Cell Biol. 2005 Jun;25(12):5292-305
references.pmid: 15923642
references.citation: Methods Mol Biol. 2010;587:303-26
references.pmid: 20225159
references.citation: EMBO Rep. 2001 Dec;2(12):1095-100
references.pmid: 11743022
references.citation: Mol Cell. 2006 Mar 17;21(6):811-23
references.pmid: 16543150
references.citation: Epigenetics. 2010 Apr;5(3):185-8
references.pmid: 20305383
references.citation: BMC Genomics. 2008 Jan 10;9:7
references.pmid: 18186930
references.citation: Annu Rev Genet. 2005;39:615-51
references.pmid: 16285873
references.citation: Genes Dev. 2005 Oct 1;19(19):2284-8
references.pmid: 16204179
references.citation: PLoS Biol. 2010 Jan;8(1):e1000276
references.pmid: 20052282
references.citation: Genes Dev. 2006 Apr 1;20(7):858-70
references.pmid: 16547172
references.citation: Int J Cancer. 2008 Mar 15;122(6):1207-13
references.pmid: 18058815
references.citation: Trends Genet. 2009 May;25(5):226-33
references.pmid: 19359064
references.citation: Nat Genet. 2005 Apr;37(4):391-400
references.pmid: 15765097
references.citation: Genome Biol. 2010;11(4):205
references.pmid: 20441602
references.citation: Cancer Res. 2008 Aug 15;68(16):6810-21
references.pmid: 18701507
references.citation: Annu Rev Genet. 2008;42:733-72
references.pmid: 18729722
references.citation: Proc Natl Acad Sci U S A. 1978 Nov;75(11):5618-22
references.pmid: 281711
references.citation: Genes Dev. 2005 Oct 1;19(19):2289-94
references.pmid: 16204180
references.citation: Annu Rev Genomics Hum Genet. 2008;9:109-27
references.pmid: 18489256
references.citation: Bioessays. 2010 Aug;32(8):709-17
references.pmid: 20658709
references.citation: Mol Cell. 2009 Oct 23;36(2):290-301
references.pmid: 19854137
references.citation: Trends Genet. 2008 Aug;24(8):390-7
references.pmid: 18585818
references.citation: PLoS Biol. 2007 Sep;5(9):e232
references.pmid: 17760505
references.citation: Genes Dev. 2009 Mar 1;23(5):602-18
references.pmid: 19270160
references.citation: Cell. 2008 Aug 22;134(4):599-609
references.pmid: 18724933
references.citation: EMBO J. 2004 Jun 2;23(11):2258-68
references.pmid: 15141166
references.citation: Genes Dev. 2002 Dec 15;16(24):3186-98
references.pmid: 12502740
references.citation: Heredity (Edinb). 2005 Aug;95(2):118-28
references.pmid: 15931241
references.citation: Trends Genet. 2005 May;21(5):249-53
references.pmid: 15851056
references.citation: Mol Cell Biol. 2005 Nov;25(21):9175-88
references.pmid: 16227571
references.citation: Nucleic Acids Res. 2010 Jun;38(10):3209-21
references.pmid: 20139418
references.citation: Mol Cell. 2000 Feb;5(2):367-75
references.pmid: 10882077
references.citation: J Biol. 2007;6(1):1
references.pmid: 17381829
references.citation: Chromosome Res. 2006;14(4):417-31
references.pmid: 16821137
references.citation: Curr Opin Genet Dev. 2007 Apr;17(2):113-20
references.pmid: 17307352
references.citation: Nat Genet. 2006 Jan;38(1):47-53
references.pmid: 16341221
references.citation: Development. 2009 May;136(9):1399-410
references.pmid: 19363150
references.citation: Nat Rev Genet. 2007 Jan;8(1):47-57
references.pmid: 17173057
references.citation: Nature. 1965 Aug 14;207(998):785-6
references.pmid: 5885936
references.citation: Mol Cell Biol. 2008 Feb;28(3):958-66
references.pmid: 18039854
references.citation: Biochem J. 2010 Feb 09;426(2):119-23
references.pmid: 20141513
references.citation: Cell. 2005 Jun 17;121(6):873-85
references.pmid: 15960975
references.citation: Science. 2007 Nov 16;318(5853):1077-8
references.pmid: 18006729
references.citation: Mol Cell Biol. 2005 Aug;25(15):6798-810
references.pmid: 16024812
references.citation: PLoS Biol. 2007 Dec;5(12):e340
references.pmid: 18162049
references.citation: Curr Biol. 1996 Feb 1;6(2):149-62
references.pmid: 8673462
references.citation: Science. 2008 Oct 31;322(5902):750-6
references.pmid: 18974356
references.citation: Mol Cell. 2006 Dec 28;24(6):841-51
references.pmid: 17189187
references.citation: Mol Cell. 2010 Jun 25;38(6):815-26
references.pmid: 20620953
references.citation: PLoS Genet. 2009 May;5(5):e1000465
references.pmid: 19412336
references.citation: J Biol. 2006;5(1):3
references.pmid: 16507155
references.citation: Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6506-11
references.pmid: 16617109
references.citation: Trends Biochem Sci. 2006 Jan;31(1):35-40
references.pmid: 16297627
references.citation: Am J Hum Genet. 2007 Sep;81(3):475-91
references.pmid: 17701894
references.citation: Mol Cell. 2000 Feb;5(2):355-65
references.pmid: 10882076
references.citation: Dev Biol. 2001 Jun 15;234(2):275-88
references.pmid: 11396999
references.citation: PLoS Biol. 2007 Dec;5(12):e326
references.pmid: 18076287
references.citation: Science. 2006 Feb 10;311(5762):844-7
references.pmid: 16469925
references.citation: J Cell Sci. 2005 Nov 1;118(Pt 21):5047-57
references.pmid: 16234327
references.citation: Mol Cell. 2003 May;11(5):1265-77
references.pmid: 12769850
references.citation: Curr Opin Struct Biol. 2006 Jun;16(3):336-43
references.pmid: 16714106
references.citation: PLoS Biol. 2010 Feb 23;8(2):e1000318
references.pmid: 20186268
references.citation: Bioessays. 2000 Dec;22(12):1106-14
references.pmid: 11084626
references.citation: Curr Opin Genet Dev. 2008 Apr;18(2):175-80
references.pmid: 18295474
references.citation: PLoS Genet. 2008 May 02;4(5):e1000066
references.pmid: 18451980
references.citation: Biochem Soc Trans. 2009 Aug;37(Pt 4):910-3
references.pmid: 19614617
references.citation: Mol Cell Biol. 2008 Jan;28(1):397-409
references.pmid: 17967868
references.citation: PLoS Biol. 2010 Feb 23;8(2):e1000320
references.pmid: 20186269