title: Human dermal tissue allograft use in treating chronic pilonidal sinus.
abstract: A study was conducted to try to improve upon existing conservative techniques in the treatment of chronic pilonidal sinus by using human dermal tissue allograft. A prospective study of 46 consecutive patients undergoing 47 operations for pilonidal disease was conducted by three surgeons. All patients underwent a conservative surgical technique with injection of human dermal tissue allograft and primary wound closure on an ambulatory basis. Sixty percent of patients required no postoperative narcotic use. Eighty-five percent missed no work or school. Sixty-six percent healed primarily. Thirty-three percent of patients developed minor wound complications that quickly responded to suture removal and drainage. There were no wound failures. The recurrence rate was 11% with a median follow-up of 15 months. This study demonstrates that primary closure is possible when combined with a conservative technique in treating uncomplicated pilonidal disease. This operative approach merits further investigation.
authors.affiliation: Department of Surgery, St. Francis Hospital and Medical Center, Hartford, CT 06105, USA. jimanderin@yahoo.com
authors.forename: James J
authors.initials: JJ
authors.lastname: Matino
authors.forename: Saumitra
authors.initials: S
authors.lastname: Banerjee
authors.forename: Steven H
authors.initials: SH
authors.lastname: Brown
authors.forename: Jill E
authors.initials: JE
authors.lastname: Waldron
mesh_terms: D000293:Adolescent; D000328:Adult; D003094:Collagen / Q000627:therapeutic use*; D003475:Curettage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010864:Pilonidal Sinus / Q000601:surgery*; D011446:Prospective Studies; D016038:Skin Transplantation / Q000379:methods*; D014184:Transplantation, Homologous; D014945:Wound Healing; D055815:Young Adult
chemical_list: C471832:Cymetra; D003094:Collagen