A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on BODIPY-functionalized magnetic nanoparticles for detecting lead in living cells.
A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe(3)O(4)@SiO(2) core/shell nanoparticles 1 has been prepared. Chemosensor 1 exhibits a high affinity and selectivity for Pb(2+) over competing metal ions tested. Moreover, confocal microscopy, and flow cytometry experiments established that 1 can be used for detecting Pb(2+) levels within living cell.
Son
Hyunjong
H
Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Jinju 660-701, Korea.
Lee
Hye Young
HY
Lim
Jung Mi
JM
Kang
Dongmin
D
Han
Won Seok
WS
Lee
Shim Sung
SS
Jung
Jong Hwa
JH
D001896:Boron Compounds / Q000737:chemistry*; D052203:Ferrosoferric Oxide / Q000737:chemistry; D005434:Flow Cytometry; D006367:HeLa Cells; D006801:Humans; D007477:Ions / Q000737:chemistry; D007854:Lead / Q000032:analysis*; D008280:Magnetics; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry
C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D007477:Ions; D007854:Lead; D012822:Silicon Dioxide; D052203:Ferrosoferric Oxide