title: [Comparison of the therapeutic effects of PTBD and PTBS in treatment of malignant obstructive jaundice].
abstract: OBJECTIVE
  To summarize and compare the short-term and long-term clinical efficacy of percutaneous transhepatic biliary drainage (PTBD) and percutaneous transhepatic biliary stent (PTBS) in the treatment of malignant obstructive jaundice.
  
  
  METHODS
  210 cases of malignant obstructive jaundice underwent interventional therapy, of which 161 cases of drainage catheters placement and 49 cases of metallic stent implantation. Follow-up information was obtained through telephone review or check-up records.
  
  
  RESULTS
  The technical success rate of technique was 100%. At 3 - 5 days after treatment, the serum total bilirubin in 15 metallic stent-treated patients was decreased by (178.04 +/- 42.32) micromol/L, and direct bilirubin by (83.97 +/- 23.63) micromol/L. Compared with those of 28 cases treated with drainage catheters: (95.67 +/- 34.28) micromol/L and (49.84 +/- 28.21) micromol/L, there were statistically significant differences between the two groups (P = 0.017 and P = 0.035). At 6 - 9 days after treatment, the serum total bilirubin in 28 cases of metallic stent group was decreased by (188.22 +/- 79.90) micromol/L, and that in 126 cases of drainage catheter group decreased by (141.39 +/- 65.32) micromol/L. The difference was statistically significant (P = 0.014). But the decline value of direct bilirubin had no significant difference. The median patency period and the median survival time of the drainage catheter group were 60 and 148 days, respectively, those of metallic stent group were 197 days and 245 days. There were statistically significant differences between the two groups (P < 0.05).
  
  
  CONCLUSIONS
  The results of this study indicate that the short-term and long-term efficacies of metallic stent implantation are better than those of catheter drainage technique.
authors.affiliation: Department of Interventional Radiology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Bai
authors.forename: Chuan-Sheng
authors.initials: CS
authors.lastname: Zheng
authors.forename: Guo-Feng
authors.initials: GF
authors.lastname: Zhou
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Liang
authors.forename: Gan-Sheng
authors.initials: GS
authors.lastname: Feng
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000150:complications*; D001663:Bilirubin / Q000097:blood; D004322:Drainage / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications; D006801:Humans; D041781:Jaundice, Obstructive / Q000097:blood / Q000209:etiology / Q000628:therapy*; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications; D015607:Stents; D015996:Survival Rate
chemical_list: D001663:Bilirubin