Short interpregnancy interval and misoprostol as additive risks for uterine rupture: a case report.
BACKGROUND
Short interpregnancy interval and uterine instrumentation are risk factors for uterine rupture in subsequent pregnancies. Misoprostol as a uterotonic agent is an additive risk factor for rupture of a scarred uterus.


METHODS
Misoprostol induction for a term stillbirth was complicated by uterine rupture. Risk factors for this uterine rupture might have included interpregnancy intervals of < 7 months, prior uterine instrumentation, and misoprostol as a uterotonic agent.


CONCLUSIONS
Caution and a high index of suspicion are warranted when using misoprostol as a uterotonic agent after a short interpregnancy interval.
Henderson
Cassandra E
CE
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Montefiore North Division Medical Center, Albert Einstein College of Medicine, Bronx, New York 10466, USA. chenders@montefiore.org
Hana
Romany Gawargious
RG
Woroch
Roman
R
Reilly
Kevin D
KD
D000037:Abruptio Placentae / Q000175:diagnosis; D000293:Adolescent; D001721:Birth Intervals; D005260:Female; D006801:Humans; D007751:Labor, Induced; D016595:Misoprostol / Q000008:administration & dosage / Q000009:adverse effects*; D010120:Oxytocics / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy; D050497:Stillbirth; D014597:Uterine Rupture / Q000209:etiology*
D010120:Oxytocics; D016595:Misoprostol