Misinterpretation of results in medico-legal cases due to microdeletion in the Y-chromosome.
In an alleged rape case, for one male suspect, XX genotype and deletion at four Y-STR loci was noticed. The expressions of 18 Y-linked genes were studied to measure the extent of deletion. No expressions at two loci were observed that might have caused the misinterpretations in forensic casework.
Raina
Anupuma
A
DNA Fingerprinting Laboratory, Department of Forensic Medicine & Toxicology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. anupumaraina2001@yahoo.co.in
Yadav
Bhuvnesh
B
Ali
Sher
S
Das Dogra
Tirath
T
D002872:Chromosome Deletion; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005554:Forensic Medicine; D006801:Humans; D007248:Infertility, Male; D007883:Legislation, Medical; D008297:Male; D016133:Polymerase Chain Reaction; D012729:Sex Chromosome Aberrations; D058533:Sex Chromosome Disorders of Sex Development / Q000235:genetics