title: Blood pressure and left ventricular mass in subjects with type 2 diabetes and gingivitis or chronic periodontitis.
abstract: BACKGROUND
  This study aimed to answer the question of whether chronic periodontitis in subjects with type 2 diabetes mellitus is associated with increased left ventricular mass (LVM) and systemic and central blood pressure (CBP).
  
  
  METHODS
  One hundred and fifty-five subjects with type 2 diabetes (67 F, 88 M, mean age 61.1±6.9 years, BMI 32.7±5.7 kg/m(2)) were divided according to their periodontal status into biofilm-gingival interface - healthy (BGI-H, 14 subjects), BGI-gingivitis (BGI-G, 119 subjects) and BGI-periodontitis (BGI-P, 22 subjects) groups. In all subjects, LVM, systemic and CBP were measured. The LVM index (LVMI) was calculated.
  
  
  RESULTS
  (1) BGI-P and BGI-G subjects, respectively, had higher (mean; 95% CI) LVM (238.6 g; 206.6-267.4 and 222.8 g; 207.0-238.2) versus BGI-H subjects (170.3 g; 125.5-217.8). (2) BGI-P and BGI-G subjects, respectively, had higher (mean; 95% CI) LVM1 (95.2 g/m(2) ; 82.9-107.4) and 87.8 g/m(2) ; 81.5-94.1) versus BGI-H subjects (63.7 g/m(2) ; 45.2-62.3). (3) BGI-P subjects had higher central and systemic systolic and diastolic blood pressure than subjects from BGI-G and BGI-H groups.
  
  
  CONCLUSIONS
  In subjects with type 2 diabetes, periodontitis and gingivitis are associated with increased LVM and periodontitis is associated with increased central and systemic blood pressure.
authors.affiliation: Department of Internal Diseases, Endocrinology and Diabetology, Central Clinical Hospital MSWiA, Warsaw, Poland. Edward.Franek@cskmswia.pl
authors.forename: Edward
authors.initials: E
authors.lastname: Franek
authors.forename: Magdalena
authors.initials: M
authors.lastname: Napora
authors.forename: Anna
authors.initials: A
authors.lastname: Blach
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Budlewski
authors.forename: Dariusz
authors.initials: D
authors.lastname: Gozdowski
authors.forename: Krystyna
authors.initials: K
authors.lastname: Jedynasty
authors.forename: Jarosław
authors.initials: J
authors.lastname: Krajewski
authors.forename: Renata
authors.initials: R
authors.lastname: Gorska
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D055113:Chronic Periodontitis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D005891:Gingivitis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D017379:Hypertrophy, Left Ventricular / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000145:classification; D018709:Statistics, Nonparametric