title: Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection.
abstract: This report is based on a Hygienist Panel Meeting held at St Anne's Manor, Wokingham on 24-25 June 2009. The panel agreed that greater use should be made of antiseptics to reduce reliance on antibiotics with their associated risk of antibiotic resistance. When choosing an antiseptic for clinical use, the Biocompatibility Index, which considers both the microbiocidal activity and any cytotoxic effects of an antiseptic agent, was considered to be a useful tool. The need for longer and more proactive post-discharge surveillance of surgical patients was also agreed to be a priority, especially given the current growth of day-case surgery. The introduction of surgical safety checklists, such as the World Health Organization's Safe Surgery Saves Lives initiative, is a useful contribution to improving safety and prevention of SSIs and should be used universally. Considering sutures as 'implants', with a hard or non-shedding surface to which micro-organisms can form biofilm and cause surgical site infections, was felt to be a useful concept.
authors.affiliation: Wound Healing Research Unit, Cardiff University, Cardiff, UK. profdavidleaper@doctors.org.uk
authors.forename: David
authors.initials: D
authors.lastname: Leaper
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: McBain
authors.forename: Axel
authors.initials: A
authors.lastname: Kramer
authors.forename: Ojan
authors.initials: O
authors.lastname: Assadian
authors.forename: Jose Luis Alfonso
authors.initials: JL
authors.lastname: Sanchez
authors.forename: Jukka
authors.initials: J
authors.lastname: Lumio
authors.forename: Martin
authors.initials: M
authors.lastname: Kiernan
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage; D019072:Antibiotic Prophylaxis / Q000379:methods; D000985:Antisepsis / Q000379:methods; D001422:Bacterial Adhesion; D018441:Biofilms; D006801:Humans; D016459:Prosthesis-Related Infections / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013537:Sutures
chemical_list: D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local
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