Prostatic blue nevus.
We report the case of a 69-year-old patient with no significant personal urological history. The clinical and ultrasound examination revealed a prostatic gland with increased volume and homogenous appearance. After transurethral resection, multiples gray-brown-blackish prostatic chips were obtained, which could be confused with a malignant melanoma. The histological routine examination in conjunction with the histochemical (Fontana-Masson) and immunohistochemical (S100, HMB45) reactions established the diagnosis of prostatic blue nevus. The presence of melanin in prostatic tissue is an unusual aspect, being encountered three distinct lesions: blue nevus, melanosis and malignant melanoma. Recognition and correct classification of each of these three entities is fundamental, concerning the clinical and prognosis implications.
Anderco
Denisa
D
Department of Pathology, Emergency County Hospital, Timisoara, Romania. denisa_dobre@yahoo.com
Lazăr
Elena
E
Tăban
Sorina
S
Miclea
Fl
F
Dema
Alis
A
D000368:Aged; D003713:Dendritic Cells / Q000473:pathology; D006801:Humans; D008297:Male; D018329:Nevus, Blue / Q000473:pathology*; D011467:Prostate / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology
D009418:S100 Proteins