title: Syndrome of inappropriate secretion of antidiuretic hormone cholestasis and pericardial effusion due to brucellosis infection: a case report.
abstract: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an extremely rare complication of infectious diseases. A rare case of brucellosis complicated by syndrome of inappropriate secretion of antidiuretic hormone (SIADH) cholestasis and pericardial involvement is reported. A 27-year-old woman was admitted for fever, abdominal pain, and scleral icterus. Her medical history revealed no recent use of diuretic agents. In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. Surrenal and thyroid tests were also within normal range. Echocardiography revealed minimal pericardial effusion with normal cardiac functions. The final diagnosis was SIADH due to Brucellosis. Hyponatremia, cholestasis, and pericardial disease were resolved with effective antibrucellar treatment with streptomycine and doxycycline. After completing treatment of brucellosis, there was not any more evidence of cholestasis and pericardial fluid.
authors.affiliation: Department of Gastroenterology, Yüzüncü Yil University School of Medicine, 65200 Van, Turkey.
authors.forename: Ahmet Cumhur
authors.initials: AC
authors.lastname: Dülger
authors.forename: Ozgür
authors.initials: O
authors.lastname: Kemik
authors.forename: Aziz
authors.initials: A
authors.lastname: Sümer
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Akdeniz
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Küçükoğlu
authors.forename: Esra Turan
authors.initials: ET
authors.lastname: Canbaz
authors.forename: Veyis
authors.initials: V
authors.lastname: Itik
authors.forename: Enver
authors.initials: E
authors.lastname: Aytemiz
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