title: Bone void fillers.
abstract: For this technology overview, the tools of evidence-based medicine were used to summarize information on the effectiveness and clinical outcomes related to the usage of bone void fillers- specifically, synthetic graft materials. Comprehensive literature searches were conducted to address five key questions, which the task force that prepared the report posed as follows. Question 1 addressed the use of synthetic bone void fillers alone. Question 2 was designed to determine whether synthetic bone void fillers could successfully serve as graft extenders and eliminate the need for iliac crest bone graft. Questions 3, 4, and 5 addressed the use of allografts as a comparison with synthetic fillers because clinical results with allografts are perceived as being much closer to autografts in these areas of the spine.
authors.affiliation: University of Florida, Jacksonville, FL, USA.
authors.forename: John S
authors.initials: JS
authors.lastname: Kirkpatrick
authors.forename: Charles N
authors.initials: CN
authors.lastname: Cornell
authors.forename: Bang H
authors.initials: BH
authors.lastname: Hoang
authors.forename: Wellington
authors.initials: W
authors.lastname: Hsu
authors.forename: J Tracy
authors.initials: JT
authors.lastname: Watson
authors.forename: William C
authors.initials: WC
authors.lastname: Watters
authors.forename: Charles M
authors.initials: CM
authors.lastname: Turkelson
authors.forename: Janet L
authors.initials: JL
authors.lastname: Wies
authors.forename: Sara
authors.initials: S
authors.lastname: Anderson
mesh_terms: D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods / Q000639:trends*; D019317:Evidence-Based Medicine; D006801:Humans; D013123:Spinal Fusion / Q000379:methods; D016896:Treatment Outcome
chemical_list: D018786:Bone Substitutes