title: Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus.
abstract: We report on an intravenous drug user who presented with methicillin-sensitive Staphylococcus aureus bacteremia and endocarditis of a prosthetic tricuspid valve, with a 4-cm vegetation refractory to standard antibiotic treatment. The patient responded to intravenous daptomycin therapy clinically and microbiologically, despite an absence of surgical intervention.
authors.affiliation: Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong. ling-x-2@hotmail.com
authors.forename: Ling Ling
authors.initials: LL
authors.lastname: Cheung
authors.forename: Chiu Sun
authors.initials: CS
authors.lastname: Yue
authors.forename: Kitty
authors.initials: K
authors.lastname: Fung
authors.forename: Chung Ming
authors.initials: CM
authors.lastname: Chu
authors.forename: Eugene Yuk
authors.initials: EY
authors.lastname: Keung Tso
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017576:Daptomycin / Q000627:therapeutic use*; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D010996:Pleural Effusion / Q000188:drug therapy; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus; D017211:Treatment Failure
chemical_list: D000900:Anti-Bacterial Agents; D017576:Daptomycin