title: Single molecule: Single molecules meet systems biology.
abstract: Application of single-molecule methods to assay genome-wide mRNA and protein levels in single bacteria provides a systems-level view of their relationship.
authors.forename: Daniel
authors.initials: D
authors.lastname: Evanko
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis* / Q000235:genetics; D005798:Genes, Bacterial; D016680:Genome, Bacterial / Q000235:genetics; D057166:High-Throughput Screening Assays / Q000379:methods*; D008164:Luminescent Proteins / Q000235:genetics; D046210:Microfluidic Analytical Techniques / Q000379:methods; D012329:RNA, Bacterial / Q000032:analysis* / Q000235:genetics; D049490:Systems Biology / Q000379:methods*
chemical_list: D001426:Bacterial Proteins; D008164:Luminescent Proteins; D012329:RNA, Bacterial; C054562:yellow fluorescent protein, Bacteria
references.citation: Science. 2010 Jul 30;329(5991):533-8
references.pmid: 20671182