title: A new spin on planar cell polarity.
abstract: The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes realigned to the proximal-distal axis of organ shape by mechanical forces and cell rearrangements mediated by Dachsous.
authors.affiliation: Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029, USA.
authors.forename: Patricio
authors.initials: P
authors.lastname: Olguin
authors.forename: Marek
authors.initials: M
authors.lastname: Mlodzik
references.citation: Nature. 1987 Oct 8-14;329(6139):549-51
references.pmid: 3116434
references.citation: Dev Cell. 2010 Sep 14;19(3):389-401
references.pmid: 20817616
references.citation: Cell. 2010 Sep 3;142(5):773-86
references.pmid: 20813263
references.citation: Dev Cell. 2005 Dec;9(6):805-17
references.pmid: 16326392
references.citation: Nat Rev Genet. 2007 Jul;8(7):555-63
references.pmid: 17563758
references.citation: Dev Cell. 2006 Feb;10(2):209-22
references.pmid: 16459300
references.citation: Trends Cell Biol. 2009 Jul;19(7):295-305
references.pmid: 19560358
references.citation: Development. 2003 Oct;130(19):4501-13
references.pmid: 12925579
references.citation: Curr Biol. 2005 Sep 20;15(18):1640-4
references.pmid: 16169485
references.citation: Nat Rev Genet. 2007 Feb;8(2):126-38
references.pmid: 17230199