title: Chordoid glioma: ten years of a low-grade tumor with high morbidity.
abstract: We report two new cases of chordoid glioma of the third ventricle and review all previously published cases of this rare tumor with regard to presentation, optimum management, and outcome. Two new cases are reported with the radiological and histopathologic findings. We searched and cross-referenced PubMed and published reports of this tumor to retrieve an additional 51 cases of this tumor, which were then analyzed according to a proforma. Chordoid glioma has consistent radiological features, although some atypical elements including a cystic component are well described. The insidious presentation and morbidity of attempted surgical resection combine to give high overall morbidity. There is a high incidence of postoperative thromboembolic disturbance. Adjuvant radiosurgery has a promising role. The morbidity of this condition is likely to remain high but may be minimized by a less aggressive surgical approach together with surveillance and early use of radiosurgery.
authors.affiliation: Department of Neurosurgery, King's College Hospital, London, United Kingdom.
authors.forename: Ruth-Mary
authors.initials: RM
authors.lastname: Desouza
authors.forename: Istvan
authors.initials: I
authors.lastname: Bodi
authors.forename: Nick
authors.initials: N
authors.lastname: Thomas
authors.forename: Henry
authors.initials: H
authors.lastname: Marsh
authors.forename: Matthew
authors.initials: M
authors.lastname: Crocker
references.citation: J Neurooncol. 2003 May;63(1):39-47
references.pmid: 12814253
references.citation: Arch Pathol Lab Med. 2004 Nov;128(11):e141-5
references.pmid: 15504076
references.citation: J Clin Pathol. 2007 Nov;60(11):1294-5
references.pmid: 17965223
references.citation: Acta Neurochir (Wien). 2008 Mar;150(3):295-300; discussion 300
references.pmid: 18246456
references.citation: Neuroradiology. 2002 Oct;44(10):842-6
references.pmid: 12389135
references.citation: Acta Neuropathol. 2000 Jun;99(6):699-703
references.pmid: 10867806
references.citation: Surg Neurol. 2009 Jan;71(1):115-20; discussion 120
references.pmid: 18262609
references.citation: Acta Neuropathol. 1995;90(5):539-44
references.pmid: 8560989
references.citation: J Comput Assist Tomogr. 2000 Mar-Apr;24(2):336-8
references.pmid: 10752904
references.citation: J Neurooncol. 2006 Feb;76(3):269
references.pmid: 16568345
references.citation: Acta Cytol. 2006 Nov-Dec;50(6):691-6
references.pmid: 17152286
references.citation: Clin Neurol Neurosurg. 2008 Sep;110(8):828-33
references.pmid: 18597929
references.citation: Neurocirugia (Astur). 2007 Apr;18(2):115-22
references.pmid: 17497057
references.citation: Neurol India. 2007 Oct-Dec;55(4):406-7
references.pmid: 18040120
references.citation: Hum Pathol. 1999 Jun;30(6):723-6
references.pmid: 10374785
references.citation: Neuropathology. 2009 Feb;29(1):85-90
references.pmid: 18498285
references.citation: Pathol Int. 2003 Nov;53(11):780-5
references.pmid: 14629303
references.citation: Arch Pathol Lab Med. 2006 Apr;130(4):460-4
references.pmid: 16594739
references.citation: No Shinkei Geka. 2002 Sep;30(9):973-9
references.pmid: 12233096
references.citation: Neurol Med Chir (Tokyo). 2006 Dec;46(12):605-8
references.pmid: 17185888
references.citation: Neurosurg Focus. 2001 Jun 15;10(6):E5
references.pmid: 16724823
references.citation: J Neuropathol Exp Neurol. 1998 Mar;57(3):283-90
references.pmid: 9600220
references.citation: Pediatr Dev Pathol. 2001 Nov-Dec;4(6):564-7
references.pmid: 11826363
references.citation: Folia Neuropathol. 2003;41(3):175-82
references.pmid: 14604300
references.citation: Am J Surg Pathol. 2001 Mar;25(3):401-5
references.pmid: 11224612
references.citation: Brain Pathol. 1999 Oct;9(4):617-26
references.pmid: 10517500
references.citation: Pathology. 2006 Jun;38(3):254-7
references.pmid: 16753749
references.citation: J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9
references.pmid: 11895036
references.citation: Neuropathol Appl Neurobiol. 2005 Aug;31(4):354-61
references.pmid: 16008819
references.citation: Acta Neurochir (Wien). 2008 Nov;150(11):1183-91
references.pmid: 18936876
references.citation: J Radiol. 2005 May;86(5 Pt 1):531-2
references.pmid: 16114216
references.citation: AJNR Am J Neuroradiol. 2001 Mar;22(3):464-9
references.pmid: 11237967
references.citation: Ann Diagn Pathol. 2000 Dec;4(6):373-8
references.pmid: 11149969
references.citation: Am J Surg Pathol. 2002 Oct;26(10):1330-42
references.pmid: 12360048
references.citation: Acta Neuropathol. 2003 Aug;106(2):176-80
references.pmid: 12748871
references.citation: Surg Neurol. 2003 May;59(5):424-8
references.pmid: 12765825
references.citation: Br J Neurosurg. 2001 Apr;15(2):147-50
references.pmid: 11360380