A rare case of locally advanced fibrosarcoma of diaphysal humerus managed successfully with limb-sparing procedures after neoadjuvant chemotherapy.
Fibrosarcomas (FS) of bone are a rare malignancy accounting for less than 5% of all primary malignant bone neoplasms. Diagnosis and treatment approaches of this entity are complex and require a skilled and experienced multidisciplinary team.Authors report their experience with a case of FS of humerus showing a pathologic complete response to neo-adjuvant chemotherapy based on adriamycin, cisplatin and ifosfamid. This approach allowed limb-sparing surgery with an excellent functional and psychological result.
El Mesbahi
Omar
O
Department of Medical Oncology, Hassan II University Hospital, Route Sidi Hrazem, Fez, Morocco. elmesbahiomar@yahoo.fr
Arifi
Samia
S
Benbrahim
Zineb
Z
El Ibrahimi
Abdelhalim
A
Kettani
Fouad
F
Bennani
Amal
A
Amarti
Afaf
A
Lamrani
My Youssef Alaoui
MY
Tizniti
Siham
S
El Mrini
Abdelmajid
A
D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D018483:Diaphyses; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D014057:Tomography, X-Ray Computed
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