title: [Upper urinary tract infections in adults: about 261 episodes].
abstract: BACKGROUND
  Upper urinary tract infections are frequent. Escherichia coli is the main pathogen identified from community acquired infections.
  
  
  OBJECTIVE
  We aim to study epidemiologic, clinical and bacterial features of this infection.
  
  
  METHODS
  We identified 261 episodes that occurred in 241 patients. They were 213 females and 48 males aged of 48.75 years. Enterobacteriaceae were the main pathogens isolated in 93.5%: E. coli in 73.3% and Klebsiella pneumoniae in 15.3%. E. coli sensitivity was of 30% for amoxicillin, 98% for cefotaxim, 96% for gentamicin, 90% for ciprofloxacin and 56% for co-trimoxazole. Anterior antibiotic use was associated with low E. coli sensitivity mainly with fluoroquinolones (96 vs 77%) and co-trimoxazole (62 vs 43%). This enhances the role of antibiotic pressure on the resistance emergence.
  
  
  CONCLUSIONS
  the reasonable use of antibiotics is necessary to limit resistance extent.
authors.affiliation: Service des Maladies Infectieuses, Hôpital La Rabta, Tunis, Tunisie.
authors.forename: Rim
authors.initials: R
authors.lastname: Abdelmalek
authors.forename: Badreddine
authors.initials: B
authors.lastname: Kilani
authors.forename: Fakher
authors.initials: F
authors.lastname: Kanoun
authors.forename: Lamia
authors.initials: L
authors.lastname: Ammari
authors.forename: Hanene Tiouiri
authors.initials: HT
authors.lastname: Benaissa
authors.forename: Ahmed
authors.initials: A
authors.lastname: Goubontini
authors.forename: Faycal
authors.initials: F
authors.lastname: Zouiten
authors.forename: Taoufik Ben
authors.initials: TB
authors.lastname: Chaabane
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents