title: Hox3/zen and the evolution of extraembryonic epithelia in insects.
abstract: Insects have undergone dramatic evolutionary changes in extraembryonic development, which correlate with changes in the expression of the class-3 Hox gene zen. Here, we review the evolution of this gene in insects and point out how changes in zen expression may have affected extraembryonic development at the morphological and the genetic level.
authors.affiliation: University of Chicago, Department of Organismal Biology and Anatomy, 920 E. 58th Street, Chicago, IL 60637, USA. uschmid@uchicago.edu
authors.forename: Urs
authors.initials: U
authors.lastname: Schmidt-Ott
authors.forename: Ab Matteen
authors.initials: AM
authors.lastname: Rafiqi
authors.forename: Steffen
authors.initials: S
authors.lastname: Lemke
mesh_terms: D000818:Animals; D005075:Biological Evolution; D019521:Body Patterning / Q000235:genetics*; D004848:Epithelium / Q000502:physiology; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics* / Q000378:metabolism; D007313:Insecta / Q000033:anatomy & histology / Q000196:embryology / Q000235:genetics; D010802:Phylogeny
chemical_list: D018398:Homeodomain Proteins; C499580:Hox3 protein, insect; D019476:Insect Proteins