Invasive aspergillosis in cystic fibrosis: a fatal case in an adolescent and review of the literature.
Invasive aspergillosis is a rare complication of cystic fibrosis. In this article, we describe a case of an adolescent with cystic fibrosis, which was well-controlled previously, colonized with Aspergillus fumigatus. The patient developed fatal disseminated aspergillosis in the absence of any preexisting risk factors after a short course of intravenous corticosteroid treatment.
Massam
Joanna
J
Division of Respiratory Medicine, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Bitnun
Ari
A
Solomon
Melinda
M
Somers
Gino R
GR
Guerguerian
Anne-Marie
AM
van Wylick
Richard
R
Waters
Valerie
V
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D003550:Cystic Fibrosis / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D007155:Immunologic Factors / Q000627:therapeutic use; D008297:Male
D000305:Adrenal Cortex Hormones; D007155:Immunologic Factors