title: An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide.
abstract: Budesonide is a mixture of 22R and 22S epimers. The epimeric content of budesonide was reported in both British and European pharmacopoeias to be within the range of 60-49/40-51 for R and S epimers, respectively. In this work, contribution of the two epimers to the overall infrared spectrum of budesonide has been investigated by quantum chemical calculations.
authors.affiliation: Department of Pharmaceutical Analytical Chemistry, University of Assiut, Egypt. hareha11374@gmail.com
authors.forename: H R H
authors.initials: HR
authors.lastname: Ali
authors.forename: H G M
authors.initials: HG
authors.lastname: Edwards
authors.forename: J
authors.initials: J
authors.lastname: Kendrick
authors.forename: T
authors.initials: T
authors.lastname: Munshi
authors.forename: I J
authors.initials: IJ
authors.lastname: Scowen
mesh_terms: D019819:Budesonide / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013059:Spectrum Analysis, Raman; D013237:Stereoisomerism; D014732:Vibration; D014961:X-Ray Diffraction
chemical_list: D019819:Budesonide