title: Plaque-type morphea in children.
abstract: We present the case of a girl, aged 8-year-old, with a history of acrocyanosis and repeated respiratory infections with beta-hemolytic streptococcus, which was consulted for the presence of skin lesions in the right buttock area. Clinical examination showed, in the right buttock region, an oval plaque with a diameter about 12 cm, hard, well defined, with irregular outline. The biopsy was performed and it revealed typical aspects of plaque-type morphea. The epidermis was mostly atrophic, with areas of ridge reduction; an important proliferation of collagen fibers within superficial and deep dermis and an abundant lymphocytic inflammatory infiltrate throughout the dermal thickness reaching hypodermic level and infiltrating it. General treatment consisted of antibiotics; vitamin E; local treatment with topical cortisone; analogues of vitamin D3 to which we associated topical adjuvants with repairing and healing role applied to the biopsied area. Evolution was favorable after three months of treatment, with obvious improvement of skin lesions; skin became more elastic and the purple red contour ring disappeared.
authors.affiliation: Department of Pediatry, Filantropia, University Hospital, University of Medicine and Pharmacy of Craiova, Romania. ligstanescu@yahoo.com
authors.forename: Ligia
authors.initials: L
authors.lastname: Stănescu
authors.forename: Alina
authors.initials: A
authors.lastname: Vâlcea
authors.forename: Carmen Florina
authors.initials: CF
authors.lastname: Popescu
authors.forename: Carmen Elena
authors.initials: CE
authors.lastname: Niculescu
authors.forename: O
authors.initials: O
authors.lastname: Ciobanu
authors.forename: G
authors.initials: G
authors.lastname: Călin
mesh_terms: D001284:Atrophy; D002648:Child; D003094:Collagen; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D012594:Scleroderma, Localized / Q000150:complications / Q000473:pathology*; D012867:Skin / Q000473:pathology*
chemical_list: D003094:Collagen