title: Invasive aspergillosis in cystic fibrosis: a fatal case in an adolescent and review of the literature.
abstract: Invasive aspergillosis is a rare complication of cystic fibrosis. In this article, we describe a case of an adolescent with cystic fibrosis, which was well-controlled previously, colonized with Aspergillus fumigatus. The patient developed fatal disseminated aspergillosis in the absence of any preexisting risk factors after a short course of intravenous corticosteroid treatment.
authors.affiliation: Division of Respiratory Medicine, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Joanna
authors.initials: J
authors.lastname: Massam
authors.forename: Ari
authors.initials: A
authors.lastname: Bitnun
authors.forename: Melinda
authors.initials: M
authors.lastname: Solomon
authors.forename: Gino R
authors.initials: GR
authors.lastname: Somers
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Guerguerian
authors.forename: Richard
authors.initials: R
authors.lastname: van Wylick
authors.forename: Valerie
authors.initials: V
authors.lastname: Waters
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D003550:Cystic Fibrosis / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D007155:Immunologic Factors / Q000627:therapeutic use; D008297:Male
chemical_list: D000305:Adrenal Cortex Hormones; D007155:Immunologic Factors