title: [Wound healing potential of chitosan and its N-sulfosuccinoyl derivatives].
abstract: Comparative study of chitosan wound healing properties and its synthesized derivatives in MC-100 gel was carried out using the model of experimental full thickness skin wounds. It was determined that N-sulfosuccinoyl chitosan derivatives added into the gel in a concentration of 0.05% possess the higher wound healing activity in comparison with other chitosan derivatives and decrease the half-healing period of wounds 2-3 times in comparison with the control.
authors.forename: T P
authors.initials: TP
authors.lastname: Alekseeva
authors.forename: A A
authors.initials: AA
authors.lastname: Rakhmetova
authors.forename: O A
authors.initials: OA
authors.lastname: Bogoslovskaia
authors.forename: I P
authors.initials: IP
authors.lastname: Ol'khovskaia
authors.forename: A N
authors.initials: AN
authors.lastname: Levov
authors.forename: A V
authors.initials: AV
authors.lastname: Il'ina
authors.forename: V P
authors.initials: VP
authors.lastname: Varlamov
authors.forename: T A
authors.initials: TA
authors.lastname: Baĭtukalov
authors.forename: N N
authors.initials: NN
authors.lastname: Glushchenko
mesh_terms: D000818:Animals; D048271:Chitosan / Q000031:analogs & derivatives* / Q000494:pharmacology*; D005782:Gels; D051379:Mice; D012867:Skin / Q000187:drug effects* / Q000293:injuries; D013329:Structure-Activity Relationship; D013386:Succinates / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D005782:Gels; D013386:Succinates; D048271:Chitosan; C024599:thiosuccinic acid