title: Outcome of surgical treatment of intestinal perforation in typhoid fever.
abstract: OBJECTIVE
  To represent our clinical experience in the treatment of intestinal perforation arising from typhoid fever.
  
  
  METHODS
  The records of 22 surgically-treated patients with typhoid intestinal perforation were evaluated retrospectively.
  
  
  RESULTS
  There were 18 males and 4 females, mean age 37 years (range, 8-64 years). Presenting symptoms were fever, abdominal pain, diarrhea or constipation. Sixteen cases were subjected to segmental resection and end-to-end anastomosis, while 3 cases received 2-layered primary repair following debridement, one case with multiple perforations received 2-layered primary repair and end ileostomy, one case received segmental resection and end-to-end anastomosis followed by an end ileostomy, and one case received segmental resection and end ileostomy with mucous fistula operation. Postoperative morbidity was seen in 5 cases and mortality was found in one case.
  
  
  CONCLUSIONS
  Intestinal perforation resulting from Salmonella typhi is an important health problem in Eastern and Southeastern Turkey. In management of this illness, early and appropriate surgical intervention is vital.
authors.affiliation: Department of General Surgery, Medical Faculty, University of Yüzüncü Yil, Van 6500, Turkey. azizsumer2002@yahoo.com
authors.forename: Aziz
authors.initials: A
authors.lastname: Sümer
authors.forename: Ozgür
authors.initials: O
authors.lastname: Kemik
authors.forename: Ahmet Cumhur
authors.initials: AC
authors.lastname: Dülger
authors.forename: Aydemir
authors.initials: A
authors.lastname: Olmez
authors.forename: Ismail
authors.initials: I
authors.lastname: Hasirci
authors.forename: Erol
authors.initials: E
authors.lastname: Kişli
authors.forename: Vedat
authors.initials: V
authors.lastname: Bayrak
authors.forename: Gulay
authors.initials: G
authors.lastname: Bulut
authors.forename: Cetin
authors.initials: C
authors.lastname: Kotan
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000379:methods; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014421:Turkey; D014435:Typhoid Fever / Q000150:complications*; D055815:Young Adult
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