title: Effect of SDS on human hair: Study on the molecular structure and morphology.
abstract: This paper presents a model study to understand the effect of surfactants on the physicochemical properties of human hair. FT-IR ATR spectroscopy has been employed to understand the chemical changes induced by sodium dodecyl sulfate (SDS) on human scalp hair. In particular, the SDS induced changes in the secondary structure of protein present in the outer protective layer of hair, i.e. cuticle, have been investigated. Conformational changes in the secondary structure of protein were studied by curve fitting of the amide I band after every phase of SDS treatment. It has been found that SDS brings rearrangements in the protein backbone conformations by transforming β -sheet structure to random coil and β -turn. Additionally, AFM and SEM studies were carried out to understand the morphological changes induced on the hair surface. SEM and AFM images demonstrated the rupture and partial erosion of cuticle sublayers.
authors.affiliation: Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India. bs.chem@gmail.com
authors.forename: Bhawana
authors.initials: B
authors.lastname: Singh
authors.forename: Siva
authors.initials: S
authors.lastname: Umapathy
mesh_terms: D006197:Hair / Q000737:chemistry* / Q000187:drug effects*; D006801:Humans; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D011506:Proteins / Q000737:chemistry; D015203:Reproducibility of Results; D012967:Sodium Dodecyl Sulfate / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D011506:Proteins; D012967:Sodium Dodecyl Sulfate