title: Notoamide O, a structurally unprecedented prenylated indole alkaloid, and notoamides P-R from a marine-derived fungus, Aspergillus sp.
abstract: Notoamides O-R were isolated from a marine-derived Aspergillus sp. Notoamide O possesses a novel hemiacetal/hemiaminal ether functionality hitherto unknown among this family of prenylated indole alkaloids. The structure represents an unusual branch point for the oxidative modification of other members in the family of prenylated indole alkaloids in the biogenetic pathway.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan. sachiko@kumamoto-u.ac.jp
authors.forename: Sachiko
authors.initials: S
authors.lastname: Tsukamoto
authors.forename: Hideharu
authors.initials: H
authors.lastname: Umaoka
authors.forename: Kohei
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Ikeda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hirota
mesh_terms: D000818:Animals; D001230:Aspergillus / Q000737:chemistry*; D049872:Bivalvia / Q000382:microbiology; D026121:Indole Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009792:Oceans and Seas; D054876:Prenylation
chemical_list: D026121:Indole Alkaloids; C552228:notoamide O