title: A ligand-free copper (1) catalysed intramolecular N-arylation of diazoaminobenzenes in PEG-water: an expeditious protocol towards regiospecific 1-aryl benzotriazoles.
abstract: An efficient and highly versatile method for the synthesis of diverse regiospecific 1-arylbenzotriazoles being important medicinal scaffolds, by the copper (1) catalysed intramolecular N-arylation of diazoaminobenzenes of 2-haloaryldiazonium salts in PEG-water has been developed. A very simple reaction protocol, large number of substrate affordability and excellent yields are the main features of this methodology.
authors.affiliation: Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata-700009, India. cmukhop@yahoo.co.in
authors.forename: Chhanda
authors.initials: C
authors.lastname: Mukhopadhyay
authors.forename: Pradip Kumar
authors.initials: PK
authors.lastname: Tapaswi
authors.forename: Ray J
authors.initials: RJ
authors.lastname: Butcher
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D011092:Polyethylene Glycols / Q000737:chemistry*; D013237:Stereoisomerism; D014226:Triazenes / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D008024:Ligands; D014226:Triazenes; D014230:Triazoles; D014867:Water; D011092:Polyethylene Glycols; C402345:1,3-diphenyl-1-triazene; D003300:Copper; C012771:benzotriazole