Cutaneous angiogenesis in patient with intravascular lymphoma (IVL): A case report.
We present a case of widespread cutaneous telangiectasias in a patient with a B-cell intravascular lymphoma most likely representing tumor-induced angiogenesis. The patient presented with a rapid onset of large cutaneous telangiectasias and skin edema, followed by the development of multiorgan failure. We describe difficulties with the ante-mortem diagnosis in the patient with predominant, clinically observed, skin lesions. The patient had disseminated disease involving many organs with a rapidly fatal outcome. The final diagnosis of intravascular malignant lymphoma (IVL) was established post-mortem after morphological and immunohistochemical studies of the autopsy material.
Szuba
Andrzej
A
Department of Internal Medicine, Wroclaw Medical University, Wroclaw, Poland. szubaa@yahoo.com
Koba
Magdalena
M
Rzeszutko
Marta
M
Rzeszutko
Wojciech
W
Dziegiel
Piotr
P
Loboda
Agnieszka
A
Dulak
Jozef
J
Andrzejak
Ryszard
R
D000368:Aged; D018951:Antigens, CD20 / Q000032:analysis; D051925:CD79 Antigens / Q000032:analysis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology; D009102:Multiple Organ Failure / Q000175:diagnosis / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000098:blood supply* / Q000175:diagnosis* / Q000473:pathology; D013684:Telangiectasis / Q000175:diagnosis* / Q000473:pathology; D019043:Vascular Neoplasms / Q000175:diagnosis* / Q000473:pathology
D018951:Antigens, CD20; D051925:CD79 Antigens