title: Multicenter evaluation of the BD Max GBS assay for detection of group B streptococci in prenatal vaginal and rectal screening swab specimens from pregnant women.
abstract: A new integrated extraction and real-time PCR-based system for the detection of group B streptococci in antepartum screening samples enriched in Lim broth was compared to the CDC-recommended culture method. The BD Max GBS assay exhibited acceptable sensitivity (95%) and specificity (96.7%) compared to those of the culture method in this multisite evaluation.
authors.affiliation: BD-HandyLab, Ann Arbor, Michigan, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Riedlinger
authors.forename: Safedin H
authors.initials: SH
authors.lastname: Beqaj
authors.forename: Marsha A
authors.initials: MA
authors.lastname: Milish
authors.forename: Stephen
authors.initials: S
authors.lastname: Young
authors.forename: Rebecca
authors.initials: R
authors.lastname: Smith
authors.forename: Monique
authors.initials: M
authors.lastname: Dodd
authors.forename: Rosemary E
authors.initials: RE
authors.lastname: Hankerd
authors.forename: William D
authors.initials: WD
authors.lastname: Lebar
authors.forename: Duane W
authors.initials: DW
authors.lastname: Newton
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D016133:Polymerase Chain Reaction / Q000379:methods; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology; D011295:Prenatal Care / Q000379:methods; D011933:Reagent Kits, Diagnostic; D012007:Rectum / Q000382:microbiology; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology
chemical_list: D011933:Reagent Kits, Diagnostic
references.citation: J Clin Microbiol. 2005 Aug;43(8):4046-51
references.pmid: 16081949
references.citation: MMWR Recomm Rep. 2002 Aug 16;51(RR-11):1-22
references.pmid: 12211284
references.citation: Diagn Microbiol Infect Dis. 2007 Sep;59(1):17-22
references.pmid: 17509794
references.citation: N Engl J Med. 2000 Jul 20;343(3):175-9
references.pmid: 10900276
references.citation: Clin Infect Dis. 2004 Oct 15;39(8):1129-35
references.pmid: 15486835
references.citation: BMC Infect Dis. 2009 Sep 04;9:148
references.pmid: 19732424
references.citation: J Clin Microbiol. 2006 Mar;44(3):725-8
references.pmid: 16517846
references.citation: J Clin Microbiol. 2008 Nov;46(11):3615-20
references.pmid: 18799703
references.citation: Clin Infect Dis. 2009 Aug 1;49(3):417-23
references.pmid: 19580414