Severe coinfections of dengue and pandemic influenza A H1N1 viruses.
Here we report on 4 hospitalized patients with dengue-influenza virus coinfections. All patients were RT-PCR positive for dengue virus and pandemic influenza A H1N1. Clinical findings at presentation ranged from influenza-like illness to severe dengue. Clinical progression of the infections varied, but all developed dengue symptoms and had interstitial infiltrates. Three cases required intensive care management and 1 case was fatal.
Perez
Maria Angeles
MA
Hospital Infantil Manuel de Jesús Rivera, Ministerio de Salud, Managua, Nicaragua.
Gordon
Aubree
A
Sanchez
Felix
F
Narvaez
Federico
F
Gutierrez
Gamaliel
G
Ortega
Oscar
O
Nuñez
Andrea
A
Harris
Eva
E
Balmaseda
Angel
A
D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000821:virology*; D003716:Dengue Virus / Q000235:genetics / Q000302:isolation & purification*; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000302:isolation & purification*; D007251:Influenza, Human / Q000821:virology*; D008297:Male; D020133:Reverse Transcriptase Polymerase Chain Reaction
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