Bupropion in the treatment of depression in Parkinson's disease.
A 78-year-old female with a nine-year history of depression was hospitalized due to worsening depression and symptoms associated with Parkinson's disease (PD). Her motor abilities improved on levodopa and the depression improved after a trial of bupropion, following unsuccessful treatment with other antidepressants. We found four reports on successful treatment of depression in PD with bupropion. However, no controlled double-blind studies have been conducted so clinicians should be cautious when administering bupropion in depression in PD.
Załuska
Maria
M
IV Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland.
Dyduch
Agnieszka
A
D000368:Aged; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology; D016642:Bupropion / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology; D014057:Tomography, X-Ray Computed
D018687:Antidepressive Agents, Second-Generation; D016642:Bupropion