title: [Xanthogranuloma of the parotid gland in adults].
abstract: Juvenile xanthogranuloma (JXG) is a cutaneous non-Langerhans cell histiocytosis affecting infants. We report the first case of JXG in the parotid gland of an adult.
  
  
  METHODS
  A 52 year-old man consulted for a painful swelling of the left parotid region, progressively increasing. On physical examination, the mass was 4 cm in diameter. A second 1.5 cm diameter tumor was found in the right parotid region. MRI revealed masses with heterogeneous hypodense on T1-weighted images and with hyper dense on T2 weighted images associated with heterogeneous enhancement after gadolinium injection. The superficial and deep lobes of the parotid gland were involved. Per-operative left-side exploration revealed a lipomatous degeneration of the parotid gland and facial nerve. A lower polar parotidectomy was performed. The histological examination identified a parotid xanthogranuloma.
  
  
  CONCLUSIONS
  The JXG is usually revealed by cutaneous lesions. In fact, the morphological, immunohistochemical, and ultrastructural features of this affection lead to its diagnosis. Extra-cutaneous localizations are less frequent. The differential diagnosis is X histiocytosis.
authors.affiliation: Service ORL, CHU Habib Bourguiba, 3029 Sfax, Tunisie. houria.dhouib@tunet.tn
authors.forename: H
authors.initials: H
authors.lastname: Dhouib
authors.forename: B
authors.initials: B
authors.lastname: Hammami
authors.forename: M
authors.initials: M
authors.lastname: Sellami
authors.forename: L
authors.initials: L
authors.lastname: Mnif
authors.forename: T
authors.initials: T
authors.lastname: Boudawara
authors.forename: A
authors.initials: A
authors.lastname: Ghorbel
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D003287:Contrast Media; D003937:Diagnosis, Differential; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D008264:Macrophages / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000175:diagnosis* / Q000473:pathology; D014746:Vimentin / Q000032:analysis; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D003287:Contrast Media; D005682:Gadolinium; D014746:Vimentin; C067980:CD68 antigen, human; D000097382:CD68 Molecule