Fyodorov-Zuev keratoprosthesis implantation: long-term results in patients with multiple failed corneal grafts.
BACKGROUND
The long term results of the Fyodorov-Zuev keratoprosthesis are presented for ten patients with repeated graft failures.


METHODS
The study took place at Dr Khodadoust Eye Hospital. The Fyodorov-Zuev keratoprosthesis was implanted in ten patients with repeated graft failures, including seven patients with old trachoma, two patients with chemical injury, and a patient with thermal injury. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis.


RESULTS
Preoperative best-uncorrected visual acuity (BUVA) ranged from counting fingers to light perception (median: light perception). The keratoprosthesis dramatically improved vision in most patients. Patients retained BUVA of 20/200-20/50 in 50%, 20/60-20/100 in 30%, 20/200 in 10% and 20/400 in 10%. Overall, 90% had 1 year postoperative vision of 20/200 or better. 70% of cases had BUVA of 20/200 or better at the last follow-up (average 52 months). Of ten keratoprosthesis implanted, three have been removed, and as a result, retention rate was 70% during average follow-up of 52 months .The most common postoperative complications were retroprosthetic membrane formation (40%), uveitis (20%), glaucoma (20%), tissue overgrowth (20%), early leakage (20%), late leakage (20%), aseptic necrosis (20%), retinal detachment (10%), endophthalmitis (10%), and granulation tissue growth (10%).


CONCLUSIONS
Fyodorov-Zuev keratoprosthesis is an effective means of managing repeated corneal graft failure.
Ghaffariyeh
Alireza
A
Dr. Khodadoust Eye Hospital, Shiraz, Fars, Iran. Alirezaghaffariyeh@hotmail.com
Honarpisheh
Nazafarin
N
Karkhaneh
Akbar
A
Abudi
Reza
R
Moroz
Zinaida Ivanovna
ZI
Peyman
Alireza
A
Faramarzi
Abolhasan
A
Abasov
Fuad
F
D000328:Adult; D000368:Aged; D003316:Corneal Diseases / Q000601:surgery*; D016039:Corneal Transplantation; D005260:Female; D006084:Graft Rejection / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D012008:Recurrence; D012086:Reoperation; D017211:Treatment Failure; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology
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