[Differences in fraction of exhaled nitric oxide values measured by two offline methods or NIOXmino in adult Japanese asthmatics].
BACKGROUND
The fraction of exhaled nitric oxide (FeNO) is a useful marker of asthma control. The FeNO measurement with two offline methods and NIOXmino may be more affordable, no studies have examined the differences in FeNO values measured with various methods in adult asthmatics.


METHODS
The study population comprised 39 stable asthmatics treated with inhaled steroids at our outpatient clinic. FeNO values were measured by two offline methods (Sievers and CEIS), NIOXmino.


RESULTS
FeNO(NIOXmino) values were significantly correlated with those of FeNO(Sievers) (r=0.935, P< 0.001) and FeNOCEIS (r=0.908, P< 0.001). However, FeNO(NIOXmino) values were low compared with FeNO(Sievers) (FeNO(NIOXmino)=0.848 x FeNO(Sievers)) and FeNO(CEIS) (FeNO(NIOXmino)=0.672 x FeNO(CEIS)).


CONCLUSIONS
Differences exist in the values of FeNO measured by various methods: conversion equations are needed to compare the FeNO values among these three methods.
Tsuburai
Takahiro
T
Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital.
Tsurikisawa
Naomi
N
Higashi
Noritaka
N
Tatsuno
Sayaka
S
Fukutomi
Yuma
Y
Tanimoto
Hidenori
H
Sekiya
Kiyoshi
K
Oshikata
Chiyako
C
Otomo
Mamoru
M
Maeda
Yuji
Y
Taniguchi
Masami
M
Ikehara
Kunihiko
K
Akiyama
Kazuo
K
D001249:Asthma / Q000503:physiopathology*; D001944:Breath Tests / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000032:analysis*
D009569:Nitric Oxide