title: Recurrent myelitis after allogeneic stem cell transplantation. Report of two cases.
abstract: BACKGROUND
  Allogeneic and autologous haematopoietic stem cell transplantation are established treatment options for haematological malignancies and may possibly be employed to treat a range of genetic and autoimmune diseases.
  
  
  METHODS
  We report two patients who developed an acute myelitis within their thoracic spinal cord after allogeneic stem cell transplantation. Myelitis in these patients was not related to graft versus host disease or immune reconstitution and was responsive to intravenous methylprednisolone and cyclophosphamide.
  
  
  CONCLUSIONS
  Myelitis is a possibly disabling consequence of haematopoietic stem cell transplantation.
authors.affiliation: Hertie Institute for Clinical Brain Research, Department of General Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Voss
authors.forename: Felix
authors.initials: F
authors.lastname: Bischof
mesh_terms: D000368:Aged; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007938:Leukemia / Q000601:surgery; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009187:Myelitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D018696:Neuroprotective Agents / Q000627:therapeutic use; D012008:Recurrence; D013904:Thoracic Vertebrae
chemical_list: D018696:Neuroprotective Agents; D008775:Methylprednisolone
references.citation: Neurology. 2006 Dec 12;67(11):1990-7
references.pmid: 17159106
references.citation: J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1013-5
references.pmid: 18223013
references.citation: Semin Neurol. 2004 Dec;24(4):427-34
references.pmid: 15637654
references.citation: Bone Marrow Transplant. 2010 Mar;45(3):593-6
references.pmid: 19684631
references.citation: Blood. 2004 Aug 1;104(3):857-64
references.pmid: 15073038
references.citation: Curr Opin Neurol. 2007 Dec;20(6):688-92
references.pmid: 17992090