Antibiotic resistance in neonatal intensive care unit pathogens: mechanisms, clinical impact, and prevention including antibiotic stewardship.
Antimicrobial-resistant pathogens are of increasing concern in the neonatal intensive care unit population. A myriad of resistance mechanisms exist in microorganisms, and management can be complex because broad-spectrum antibiotics are increasingly needed. Control and prevention of antibiotic-resistant organisms (AROs) require an interdisciplinary team with continual surveillance. Judicious use of antibiotics; minimizing exposure to risk factors, when feasible; and effective hand hygiene are crucial interventions to reduce infection and transmission of AROs.
Patel
Sameer J
SJ
Department of Pediatrics, Columbia University, 622 West 168th Street, PH4W-475, New York, NY 10032, USA.
Saiman
Lisa
L
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D004352:Drug Resistance, Microbial; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D012307:Risk Factors
D000890:Anti-Infective Agents
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