title: Taste mixture interactions: suppression, additivity, and the predominance of sweetness.
abstract: Most of what is known about taste interactions has come from studies of binary mixtures. The primary goal of this study was to determine whether asymmetries in suppression between stimuli in binary mixtures predict the perception of tastes in more complex mixtures (e.g., ternary and quaternary mixtures). Also of interest was the longstanding question of whether overall taste intensity derives from the sum of the tastes perceived within a mixture (perceptual additivity) or from the sum of the perceived intensities of the individual stimuli (stimulus additivity). Using the general labeled magnitude scale together with a sip-and-spit procedure, we asked subjects to rate overall taste intensity and the sweetness, sourness, saltiness and bitterness of approximately equi-intense sucrose, NaCl, citric acid and QSO(4) stimuli presented alone and in all possible binary, ternary and quaternary mixtures. The results showed a consistent pattern of mixture suppression in which sucrose sweetness tended to be both the least suppressed quality and the strongest suppressor of other tastes. The overall intensity of mixtures was found to be predicted best by perceptual additivity. A second experiment that was designed to rule out potentially confounding effects of the order of taste ratings and the temperature of taste solutions replicated the main findings of the first experiment. Overall, the results imply that mixture suppression favors perception of sweet carbohydrates in foods at the expense of other potentially harmful ingredients, such as high levels of sodium (saltiness) and potential poisons or spoilage (bitterness and sourness).
authors.affiliation: The John B. Pierce Laboratory, United States. green@jbpierce.org
authors.forename: Barry G
authors.initials: BG
authors.lastname: Green
authors.forename: Juyun
authors.initials: J
authors.lastname: Lim
authors.forename: Floor
authors.initials: F
authors.lastname: Osterhoff
authors.forename: Karen
authors.initials: K
authors.lastname: Blacher
authors.forename: Danielle
authors.initials: D
authors.lastname: Nachtigal
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D019343:Citric Acid / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D012965:Sodium Chloride / Q000494:pharmacology; D013395:Sucrose / Q000494:pharmacology; D013649:Taste / Q000187:drug effects / Q000502:physiology*; D055697:Taste Perception / Q000187:drug effects / Q000502:physiology*; D013652:Taste Threshold / Q000187:drug effects / Q000502:physiology*
chemical_list: D019343:Citric Acid; D012965:Sodium Chloride; D013395:Sucrose
references.citation: Chem Senses. 1995 Dec;20(6):609-23
references.pmid: 8788095
references.citation: Physiol Behav. 1982 May;28(5):905-10
references.pmid: 7100291
references.citation: Nature. 1997 Jun 5;387(6633):563
references.pmid: 9177340
references.citation: Percept Psychophys. 1982 Dec;32(6):504-10
references.pmid: 7167347
references.citation: J Exp Psychol. 1969 Apr;80(1):101-5
references.pmid: 5787406
references.citation: Chem Senses. 1996 Jun;21(3):323-34
references.pmid: 8670711
references.citation: Percept Psychophys. 2004 May;66(4):642-50
references.pmid: 15311663
references.citation: Chem Senses. 2001 Oct;26(8):993-1003
references.pmid: 11595676
references.citation: Percept Psychophys. 1991 Jan;49(1):1-9
references.pmid: 2011446
references.citation: Physiol Behav. 1988;43(4):515-9
references.pmid: 3194473
references.citation: Percept Psychophys. 1984 Jan;35(1):1-4
references.pmid: 6709469
references.citation: Chem Senses. 2004 Sep;29(7):617-28
references.pmid: 15337686
references.citation: Perception. 2002;31(5):617-35
references.pmid: 12044101
references.citation: J Comp Physiol Psychol. 1979 Jun;93(3):538-47
references.pmid: 479396
references.citation: Physiol Behav. 1985 Nov;35(5):779-83
references.pmid: 4080842
references.citation: Chem Senses. 2004 Jul;29(6):513-21
references.pmid: 15269123
references.citation: Physiol Behav. 1994 Dec;56(6):1243-9
references.pmid: 7878097
references.citation: Physiol Behav. 1975 May;14(5):643-9
references.pmid: 1135328
references.citation: Pharm Res. 2002 Jul;19(7):1019-26
references.pmid: 12180534
references.citation: J Chronic Dis. 1984;37(3):195-208
references.pmid: 6365942
references.citation: Physiol Behav. 1979 Feb;22(2):347-51
references.pmid: 441173
references.citation: Chem Senses. 2004 Jun;29(5):431-9
references.pmid: 15201210
references.citation: Brain Res. 1987 Jun 23;414(1):197-203
references.pmid: 3620922
references.citation: Percept Psychophys. 1993 Dec;54(6):751-8
references.pmid: 8134244
references.citation: Dev Psychobiol. 2001 Jan;38(1):67-77
references.pmid: 11150062
references.citation: Percept Psychophys. 1990 Oct;48(4):326-30
references.pmid: 2243756
references.citation: Percept Psychophys. 1995 Jan;57(1):18-26
references.pmid: 7885804
references.citation: Am J Cardiol. 1976 Nov 23;38(6):768-85
references.pmid: 793367