title: A rare case of locally advanced fibrosarcoma of diaphysal humerus managed successfully with limb-sparing procedures after neoadjuvant chemotherapy.
abstract: Fibrosarcomas (FS) of bone are a rare malignancy accounting for less than 5% of all primary malignant bone neoplasms. Diagnosis and treatment approaches of this entity are complex and require a skilled and experienced multidisciplinary team.Authors report their experience with a case of FS of humerus showing a pathologic complete response to neo-adjuvant chemotherapy based on adriamycin, cisplatin and ifosfamid. This approach allowed limb-sparing surgery with an excellent functional and psychological result.
authors.affiliation: Department of Medical Oncology, Hassan II University Hospital, Route Sidi Hrazem, Fez, Morocco. elmesbahiomar@yahoo.fr
authors.forename: Omar
authors.initials: O
authors.lastname: El Mesbahi
authors.forename: Samia
authors.initials: S
authors.lastname: Arifi
authors.forename: Zineb
authors.initials: Z
authors.lastname: Benbrahim
authors.forename: Abdelhalim
authors.initials: A
authors.lastname: El Ibrahimi
authors.forename: Fouad
authors.initials: F
authors.lastname: Kettani
authors.forename: Amal
authors.initials: A
authors.lastname: Bennani
authors.forename: Afaf
authors.initials: A
authors.lastname: Amarti
authors.forename: My Youssef Alaoui
authors.initials: MY
authors.lastname: Lamrani
authors.forename: Siham
authors.initials: S
authors.lastname: Tizniti
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: El Mrini
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D018483:Diaphyses; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D014057:Tomography, X-Ray Computed
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