title: Evaluation of erythrocytes, platelets, and serum iron profile in dogs with chronic enteropathy.
abstract: The aim of this study is to evaluate iron status, erythrocyte, and platelet modifications in dogs with chronic enteropathy (CE). Dogs were grouped as food-responsive diarrhea (FRD, n = 11), antibiotic-responsive diarrhea (ARD, n = 5), and steroid-responsive diarrhea (SRD, n = 6) relating to therapeutic-response. Clinical and haematological findings, evidence of gastrointestinal blood loss, and iron metabolism were evaluated before and after treatment. A mild normocytic or microcytic anemia and thrombocytosis were identified, respectively in 18.0% and 31.8% of CE dogs. No significant differences between pre- and posttreatment of hematocrit, haemoglobin, and mean corpuscular volume, platelet count and mean platelet volume were found. Statistical analysis pointed out significant differences between pre- and posttreatment in serum iron (P < .03) and unsaturated iron binding capacity (UIBC) (P < .01). No significant correlations were found between these parameters and canine Inflammatory Bowel Disease activity index and pattern of CE as well.
authors.affiliation: Department of Veterinary Clinics, University of Pisa, via Livornese lato monte, I-56122 San Piero a Grado, Pisa, Italy.
authors.forename: Veronica
authors.initials: V
authors.lastname: Marchetti
authors.forename: George
authors.initials: G
authors.lastname: Lubas
authors.forename: Andrea
authors.initials: A
authors.lastname: Lombardo
authors.forename: Michele
authors.initials: M
authors.lastname: Corazza
authors.forename: Grazia
authors.initials: G
authors.lastname: Guidi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cardini
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