title: Gene flow between Zhuang and Han populations in the China-Vietnam borderland.
abstract: In epidemiological studies, it is easier to glean information from isolated populations with simple genetic backgrounds than from populations with relatively complex genetic backgrounds. Regarded as an isolated population, the Minz (Hei-Yi Zhuang) in Napo County (in the China-Vietnam borderland) has been the subject of numerous recent studies. To assess the genetic isolation of this population, we studied Y chromosome and mitochondrial DNA from Minz and Han in Napo. Both populations exhibited southern Chinese genetic characteristics in both paternal and maternal lineages. Using NETWORK analyses, we found pronounced gene flow between these two populations only in maternal lineages. We also observed gene flow from other populations into the Minz gene pool. We thus concluded that the Minz is not a genetically isolated population and it is increasingly difficult to find isolated populations in mainland East Asia.
authors.affiliation: Department of Pathophysiology and Institute of Cardiovascular Disease, Guangxi Medical University, Nanning, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhao
authors.forename: Shangling
authors.initials: S
authors.lastname: Pan
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Qin
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Cai
authors.forename: Yan
authors.initials: Y
authors.lastname: Lu
authors.forename: Sara E
authors.initials: SE
authors.lastname: Farina
authors.forename: Chengwu
authors.initials: C
authors.lastname: Liu
authors.forename: Junhua
authors.initials: J
authors.lastname: Peng
authors.forename: Jieshun
authors.initials: J
authors.lastname: Xu
authors.forename: Ruixing
authors.initials: R
authors.lastname: Yin
authors.forename: Shilin
authors.initials: S
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Li
mesh_terms: D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D002681:China / Q000453:epidemiology / Q000208:ethnology; D041322:Chromosomes, Human, Y / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005260:Female; D051456:Gene Flow; D005828:Genetics, Population; D006801:Humans; D008297:Male; D014744:Vietnam / Q000453:epidemiology / Q000208:ethnology
chemical_list: D004272:DNA, Mitochondrial