Chiral cobalt-catalyzed enantioselective aerobic oxidation of α-hydroxy esters.
A chiral cobalt-catalyzed enantioselective aerobic oxidative kinetic resolution of (±)-α-hydroxy esters, using molecular oxygen as a sole oxidant, is reported and a maximum of selectivity factor (s) 31.9 was achieved with >99% enantiomeric excess for unreacted α-hydroxy esters.
Alamsetti
Santosh Kumar
SK
Department of Chemistry, Indian Institute of Technology Madras, Chennai, 600 036, India.
Sekar
Govindasamy
G
D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D017665:Hydroxyl Radical / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D004952:Esters; D017665:Hydroxyl Radical; D003035:Cobalt