title: Assembling complex I with ACAD9.
abstract: Acyl-Co dehydrogenase 9 (ACAD9) was thought to play a role in fatty acid oxidation. Nouws et al. (2010) reveal a novel and essential role for this enzyme in mitochondrial complex I assembly. A mutation in ACAD9 causes an isolated complex I deficiency in a subset of patients with mitochondrial disease.
authors.affiliation: University of California, San Diego, La Jolla, 92093-0322, USA. ischeffler@ucsd.edu
authors.forename: Immo E
authors.initials: IE
authors.lastname: Scheffler