title: Validation of a Mini-Mental State Examination (MMSE) for the Persian population: a pilot study.
abstract: The objective of the study was to develop and validate a translated and culturally adapted Mini-Mental State Examination (MMSE) for the Persian-speaking population. The MMSE was translated into Persian. Two groups of neurologically intact subjects (n = 100) and subjects with Alzheimer's disease (n = 13) were studied. The difference between groups on the mean total scores of the Persian MMSE was statistically significant (control = 28.62 +/- 2.09; subjects with Alzheimer's disease = 11.77 +/- 5.66; p < .001). The cutoff score of 23 was the best cutoff score for our subjects with a sensitivity and specificity of 98% and 100%, respectively. There was a significant correlation between the Persian MMSE score and the level of education (r = .46) and with age (r = -.77). There was no significant correlation between the Persian MMSE and gender. The Persian MMSE was found to be valid for discrimination of cognitive impairment in the Persian-speaking community.
authors.affiliation: Faculty of Rehabilitation, Tehran University of Medical Sciences, Enghelab Ave., Pitch-e-shemiran, Tehran, Iran. nakhostin@sina.tums.ac.ir
authors.forename: Noureddin Nakhostin
authors.initials: NN
authors.lastname: Ansari
authors.forename: Soofia
authors.initials: S
authors.lastname: Naghdi
authors.forename: Scott
authors.initials: S
authors.lastname: Hasson
authors.forename: Leala
authors.initials: L
authors.lastname: Valizadeh
authors.forename: Shohreh
authors.initials: S
authors.lastname: Jalaie
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology; D016022:Case-Control Studies; D003431:Cross-Cultural Comparison; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards*; D010865:Pilot Projects; D011594:Psychometrics; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D014175:Translating; D055815:Young Adult