title: [Phlebothrombosis of the amputation femur stump: certain aspects of pathogenesis and prophylactics].
abstract: An experience with treatment of 455 patients who underwent transfemoral amputation was analyzed. In 54 patients (11.9%) phlebothrombosis of the femur stump developed in the early postoperative period. Certain little studied problems of pathogenesis of the complication in question are considered, possible variants of the clinical picture are described. Negative role of thrombosis of the femur stump veins is shown in the development of thromboembolism of the lung artery that was a direct cause of death of 20 patients. Prophylactics of stump phlebothrombosis allows getting less frequency of the development of this complication, decreased lethality, improvement of quality of life and duration of life of patients after transfemoral amputation.
authors.forename: M V
authors.initials: MV
authors.lastname: Mel'nikov
authors.forename: A V
authors.initials: AV
authors.lastname: Davydov
mesh_terms: D000368:Aged; D000672:Amputation Stumps / Q000098:blood supply* / Q000503:physiopathology*; D005260:Female; D005269:Femur / Q000098:blood supply*; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000503:physiopathology; D013923:Thromboembolism / Q000209:etiology; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*