Outcome of renal transplant in patients with abnormal urinary tract.
OBJECTIVE
To determine whether surgical procedures of the lower urinary tract in patients with uropathies affect evolution of the graft in renal transplantation.


METHODS
156 kidney transplantations were performed in 150 patients with end-stage renal failure due to urologic disorders. The patients were classified into three groups: A, patients who did not require surgery in the lower urinary tract; B, required surgery and preserved adequate bladder function, and C, required surgery due to vesical dysfunction.


RESULTS
Graft survival rates at 1 year were 93.38% in group A, 95.45% in group B and 93% in group C. Rates at 5 years post-transplantation were 82.45, 79.85 and 86.58% for each group, respectively (not significant). Complications were vesicoureteral stenosis: 2 in group A, 3 in B and 1 in C; vesicoureteral reflux: 1 in group A, 1 in B and 10 in C; distal ureteral necrosis: 2 cases in group A, 2 in B and 1 in C; upper urinary tract infection: 12, 23.1 and 42.2% in each group, respectively.


CONCLUSIONS
Children with reconstructed urinary tract may be good candidates for kidney transplantation despite the higher frequency of urinary infections. Thus, careful and strict post-surgical urologic follow-up is mandatory.
Sager
Cristian
C
Urology Department, Hospital de Pediatría Dr. Juan P. Garrahan, Buenos Aires, Argentina. cristian.sager@gmail.com
Burek
Carol
C
Durán
Víctor
V
Corbetta
Juan Pablo
JP
Weller
Santiago
S
Paz
Enrique
E
López
Juan Carlos
JC
D002648:Child; D005260:Female; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications; D016896:Treatment Outcome; D014570:Urologic Diseases / Q000150:complications / Q000601:surgery*
Transplantation. 2010 Jun 15;89(11):1299-1307
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