title: Synchronous acquisition of hyperpolarised 3He and 1H MR images of the lungs - maximising mutual anatomical and functional information.
abstract: The development of hybrid medical imaging scanners has allowed imaging with different detection modalities at the same time, providing different anatomical and functional information within the same physiological time course with the patient in the same position. Until now, the acquisition of proton MRI of lung anatomy and hyperpolarised gas MRI of lung function required separate breath-hold examinations, meaning that the images were not spatially registered or temporally synchronised. We demonstrate the spatially registered concurrent acquisition of lung images from two different nuclei in vivo. The temporal and spatial registration of these images is demonstrated by a high degree of mutual consistency that is impossible to achieve in separate scans and breath holds.
authors.affiliation: Unit of Academic Radiology, University of Sheffield, Sheffield, UK. j.m.wild@sheffield.ac.uk
authors.forename: Jim M
authors.initials: JM
authors.lastname: Wild
authors.forename: Salma
authors.initials: S
authors.lastname: Ajraoui
authors.forename: Martin H
authors.initials: MH
authors.lastname: Deppe
authors.forename: Steven R
authors.initials: SR
authors.lastname: Parnell
authors.forename: Helen
authors.initials: H
authors.lastname: Marshall
authors.forename: Juan
authors.initials: J
authors.lastname: Parra-Robles
authors.forename: Rob H
authors.initials: RH
authors.lastname: Ireland
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006371:Helium; D006801:Humans; D008168:Lung / Q000033:anatomy & histology* / Q000502:physiology*; D008175:Lung Neoplasms / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D006371:Helium