title: [Evidence-based therapy of depression: S3 guidelines on unipolar depression].
abstract: Unipolar depressive disorders are among the most frequent reasons for utilizing the health care system. Although efficacious treatments are available and further advances have recently been made there is still a need for improving diagnostic and therapeutic procedures. Alignment of treatment on evidence-based treatment guidelines establishes an essential mainstay. The new S3 and National Health Care guidelines on unipolar depression, the compilation of which was coordinated by the German Society of Psychiatry, Psychotherapy and Neurology (DGPPN) and which were approved by 29 scientific and professional associations, is the ambitious effort to present state of the art evidence and clinical consensus for the treatment of depression. For pharmacotherapy of depression differentiated recommendations can be given, also separate from and in addition to psychotherapy.
authors.affiliation: Institut und Poliklinik für Medizinische Psychologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52 (W 26), 20246, Hamburg, Deutschland. m.haerter@uke.uni-hamburg.de
authors.forename: M
authors.initials: M
authors.lastname: Härter
authors.forename: C
authors.initials: C
authors.lastname: Klesse
authors.forename: I
authors.initials: I
authors.lastname: Bermejo
authors.forename: T
authors.initials: T
authors.lastname: Bschor
authors.forename: J
authors.initials: J
authors.lastname: Gensichen
authors.forename: T
authors.initials: T
authors.lastname: Harfst
authors.forename: M
authors.initials: M
authors.lastname: Hautzinger
authors.forename: C
authors.initials: C
authors.lastname: Kolada
authors.forename: I
authors.initials: I
authors.lastname: Kopp
authors.forename: C
authors.initials: C
authors.lastname: Kühner
authors.forename: M
authors.initials: M
authors.lastname: Lelgemann
authors.forename: J
authors.initials: J
authors.lastname: Matzat
authors.forename: B
authors.initials: B
authors.lastname: Meyerrose
authors.forename: C
authors.initials: C
authors.lastname: Mundt
authors.forename: W
authors.initials: W
authors.lastname: Niebling
authors.forename: G
authors.initials: G
authors.lastname: Ollenschläger
authors.forename: R
authors.initials: R
authors.lastname: Richter
authors.forename: H
authors.initials: H
authors.lastname: Schauenburg
authors.forename: H
authors.initials: H
authors.lastname: Schulz
authors.forename: S
authors.initials: S
authors.lastname: Weinbrenner
authors.forename: F
authors.initials: F
authors.lastname: Schneider
authors.forename: M
authors.initials: M
authors.lastname: Berger
mesh_terms: D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000175:diagnosis* / Q000628:therapy*; D019317:Evidence-Based Medicine / Q000592:standards*; D005858:Germany; D006801:Humans; D009462:Neurology / Q000592:standards*; D017410:Practice Guidelines as Topic
references.citation: J Clin Psychiatry. 2003;64 Suppl 2:3-7
references.pmid: 12625792
references.citation: Cochrane Database Syst Rev. 2002 Oct 21;(4):CD003944
references.pmid: 12519625
references.citation: JAMA. 2002 Apr 10;287(14):1807-14
references.pmid: 11939866
references.citation: Nervenarzt. 2009 May;80(5):540, 542-4, 546-8 passim
references.pmid: 19404606
references.citation: Harv Rev Psychiatry. 2003 May-Jun;11(3):133-41
references.pmid: 12893503
references.citation: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2008 Apr;51(4):451-7
references.pmid: 18345469
references.citation: Int J Qual Health Care. 2006 Apr;18(2):113-9
references.pmid: 16260456
references.citation: Biol Psychiatry. 2002 Jan 15;51(2):183-8
references.pmid: 11822997
references.citation: Z Arztl Fortbild Qualitatssich. 2003 Nov;97 Suppl 4:16-35
references.pmid: 14710665
references.citation: Can J Psychiatry. 2001 Jun;46 Suppl 1:5S-90S
references.pmid: 12371438
references.citation: Arch Gen Psychiatry. 1989 Nov;46(11):971-82; discussion 983
references.pmid: 2684085
references.citation: Nervenarzt. 2007 Nov;78 Suppl 3:585-94; quiz 595
references.pmid: 17934708
references.citation: JAMA. 2010 Jan 6;303(1):47-53
references.pmid: 20051569
references.citation: Eur Arch Psychiatry Clin Neurosci. 2005 Dec;255(6):387-400
references.pmid: 15868067
references.citation: Pharmacopsychiatry. 2004 Nov;37(6):243-65
references.pmid: 15551191
references.citation: N Engl J Med. 2008 Jan 17;358(3):252-60
references.pmid: 18199864
references.citation: J Clin Psychol Med Settings. 2008 Jun;15(2):140-7
references.pmid: 19104978
references.citation: Lancet. 2003 Feb 22;361(9358):653-61
references.pmid: 12606176
references.citation: Z Psychosom Med Psychother. 2010;56(4):334-42
references.pmid: 21243603
references.citation: Psychol Med. 2004 May;34(4):597-611
references.pmid: 15099415
references.citation: Clin Psychol Rev. 2010 Feb;30(1):51-62
references.pmid: 19781837
references.citation: J Clin Psychiatry. 1998;59 Suppl 15:35-41
references.pmid: 9786309
references.citation: Fortschr Neurol Psychiatr. 2001 Sep;69(9):390-401
references.pmid: 11536055
references.citation: J Affect Disord. 2000 Apr;58(1):19-36
references.pmid: 10760555
references.citation: Cochrane Database Syst Rev. 2008 Oct 08;(4):CD000448
references.pmid: 18843608
references.citation: JAMA. 2002 Apr 10;287(14):1840-7
references.pmid: 11939870
references.citation: Biol Psychiatry. 1999 Aug 15;46(4):445-53
references.pmid: 10459393
references.citation: Z Arztl Fortbild Qualitatssich. 2003 Nov;97 Suppl 4:36-43
references.pmid: 14710666
references.citation: JAMA. 2003 Jun 18;289(23):3152-60
references.pmid: 12813121
references.citation: J Clin Psychopharmacol. 2002 Feb;22(1):40-5
references.pmid: 11799341
references.citation: Can J Psychiatry. 2003 Aug;48(7):440-8
references.pmid: 12971013
references.citation: Fortschr Neurol Psychiatr. 2005 May;73(5):249-58
references.pmid: 15880303
references.citation: Cochrane Database Syst Rev. 2000;(2):CD001130
references.pmid: 10796749
references.citation: J Clin Psychiatry. 2007 Jun;68(6):935-40
references.pmid: 17592920
references.citation: J Gen Intern Med. 1997 Jul;12(7):439-45
references.pmid: 9229283
references.citation: Am J Psychiatry. 2006 Nov;163(11):1905-17
references.pmid: 17074942
references.citation: Z Psychosom Med Psychother. 2009;55(4):354-64
references.pmid: 20229483
references.citation: Cochrane Database Syst Rev. 2001;(2):CD000561
references.pmid: 11405969
references.citation: Z Arztl Fortbild Qualitatssich. 2004 Mar;98(2):101-7
references.pmid: 15106488
references.citation: Arch Gen Psychiatry. 2004 Jul;61(7):714-9
references.pmid: 15237083
references.citation: J ECT. 2004 Mar;20(1):13-20
references.pmid: 15087991
references.citation: Nat Rev Neurosci. 2008 Oct;9(10):788-96
references.pmid: 18784657
references.citation: PLoS Med. 2008 Feb;5(2):e45
references.pmid: 18303940
references.citation: Cochrane Database Syst Rev. 2004;(2):CD004050
references.pmid: 15106233