title: Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1.
abstract: This study investigates the association of rheumatoid arthritis-associated single nucleotide polymorphisms in endometriosis. We found an association of CCL21 (rs2812378) and HLA-DRB1 (rs660895) with moderate to severe endometriosis.
authors.affiliation: Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet/Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Johanna
authors.initials: J
authors.lastname: Sundqvist
authors.forename: Henrik
authors.initials: H
authors.lastname: Falconer
authors.forename: Maria
authors.initials: M
authors.lastname: Seddighzadeh
authors.forename: Alexandra
authors.initials: A
authors.lastname: Vodolazkaia
authors.forename: Amelie
authors.initials: A
authors.lastname: Fassbender
authors.forename: Cleophas
authors.initials: C
authors.lastname: Kyama
authors.forename: Attila
authors.initials: A
authors.lastname: Bokor
authors.forename: Olof
authors.initials: O
authors.lastname: Stephansson
authors.forename: Leonid
authors.initials: L
authors.lastname: Padyukov
authors.forename: Kristina
authors.initials: K
authors.lastname: Gemzell-Danielsson
authors.forename: Thomas M
authors.initials: TM
authors.lastname: D'Hooghe
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D054421:Chemokine CCL21 / Q000235:genetics*; D004715:Endometriosis / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D012720:Severity of Illness Index
chemical_list: C515478:CCL21 protein, human; D054421:Chemokine CCL21; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains