title: A reduced phytate diet does not reduce endogenous fecal zinc in children on a habitual high-phytate diet.
abstract: Ten Malawian children, ages 3 to 5 years, at risk for zinc deficiency and receiving a habitual maize-based high-phytate diet, received maize after phytate reduction for 40 days and had their endogenous fecal zinc (EFZ) measured using stable isotope techniques before and after phytate reduction. The phytate:Zn of the diet before reduction was 23.0 and afterward was 7.6. EFZ was similar before and after dietary phytate reduction, 1.15 ± 0.33 and 1.17 ± 0.16 mg/day, respectively. EFZ was not affected by dietary phytate in this population.
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
authors.forename: Gregg
authors.initials: G
authors.lastname: Kennedy
authors.forename: K Michael
authors.initials: KM
authors.lastname: Hambidge
authors.forename: Mark
authors.initials: M
authors.lastname: Manary
mesh_terms: D002675:Child, Preschool; D004032:Diet; D002523:Edible Grain / Q000737:chemistry; D005243:Feces / Q000737:chemistry*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D008295:Malawi; D008297:Male; D010833:Phytic Acid / Q000008:administration & dosage* / Q000032:analysis; D011446:Prospective Studies; D003313:Zea mays / Q000737:chemistry*; D015032:Zinc / Q000032:analysis* / Q000172:deficiency
chemical_list: D010833:Phytic Acid; D015032:Zinc