title: Detection, evaluation, and management of iron-restricted erythropoiesis.
abstract: Progress in our understanding of iron-restricted erythropoiesis has been made possible by important advances in defining the molecular mechanisms of iron homeostasis. The detection and diagnostic classification of iron-restricted erythropoiesis can be a challenging process for the clinician. Newer assays for markers of inflammation may allow more targeted management of the anemia in these conditions. The availability of new intravenous iron preparations provides new options for the treatment of iron-restricted erythropoiesis. This review summarizes recent advances regarding the detection, evaluation, and management of iron-restricted erythropoiesis.
authors.affiliation: Departments of Pathology and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. ltgoodnough@stanfordmed.org
authors.forename: Lawrence Tim
authors.initials: LT
authors.lastname: Goodnough
authors.forename: Elizabeta
authors.initials: E
authors.lastname: Nemeth
authors.forename: Tomas
authors.initials: T
authors.lastname: Ganz
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy*; D004920:Erythropoiesis; D006801:Humans; D000090463:Iron Deficiencies; D019266:Iron, Dietary / Q000378:metabolism
chemical_list: D019266:Iron, Dietary