Development of genital warts after incident detection of human papillomavirus infection in young men.
Determining the rate at which men develop genital warts after infection with alpha genus human papillomavirus (HPV) types will provide important information for the design of prevention strategies. We conducted a cohort study of 18-21-year-old men who underwent triannual genital examinations. The 24-month cumulative genital wart incidence was 57.9% (95% confidence interval [CI], 38.1%-79.1%) among 46 men with incident detection of HPV-6 or HPV-11 infection, 2.0% (95% CI, 0.5%-7.9%) among 161 men with incident detection of infection with other HPV types, and 0.7% (95% CI, 0.2%-2.8%) among 331 men who tested negative for HPV. Our results suggest that genital warts are common after HPV-6 or HPV-11 infection in young men.
Arima
Yuzo
Y
Departments of 1Epidemiology, and 6Harborview Medical Center, University of Washington, Seattle, WA 98104, USA.
Winer
Rachel L
RL
Feng
Qinghua
Q
Hughes
James P
JP
Lee
Shu-Kuang
SK
Stern
Michael E
ME
O'Reilly
Sandra F
SF
Koutsky
Laura A
LA
D000293:Adolescent; D000328:Adult; D052685:Alphapapillomavirus; D015331:Cohort Studies; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000209:etiology* / Q000821:virology; D052140:Human papillomavirus 11; D052163:Human papillomavirus 6 / Q000502:physiology; D006801:Humans; D015994:Incidence; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications* / Q000453:epidemiology*; D012307:Risk Factors; D013997:Time Factors; D055815:Young Adult