title: Image fusion between ultrasonography and CT, MRI or PET/CT for image guidance and intervention - a theoretical and clinical study.
abstract: The aim of this thesis was to test the clinical application of image fusion involving US. The first study describes the accuracies of different methods of co-registration in a phantom. The accuracy improved if co-registration was made from points or planes close to the area examined. The second study describes the accuracy of image-guided intervention on structures invisible to US but visible to CT or MRI. We measured a rate of success of biopsies in a phantom and found a rate of success, similar to that of conventional US-guided biopsy. In the third study, we found that the number of identifiable lesions by US increased by using the fusion-guided US, and the method was helpful as guidance for contrast-enhanced US (CEUS) as it enabled us to focus on a specific area. In the fourth study we computed a program to fuse a 3D-US dataset with a PET/CT examination. We have presented some of the first results on accuracy of real-time image fusion involving US and of the application of the method to patients with liver lesions.
authors.affiliation: Department of Radiology, Rigshospitalet, Copenhagen OE, Denmark. caroline.ewertsen@dadlnet.dk
authors.forename: Caroline
authors.initials: C
authors.lastname: Ewertsen
mesh_terms: D000368:Aged; D000465:Algorithms; D001005:Anus Neoplasms / Q000175:diagnosis; D001707:Biopsy, Needle / Q000379:methods*; D019160:Endosonography; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008113:Liver Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography