A fragment-based in situ combinatorial approach to identify high-affinity ligands for unknown binding sites.
Shelke
Sachin V
SV
Institute of Molecular Pharmacy, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Cutting
Brian
B
Jiang
Xiaohua
X
Koliwer-Brandl
Hendrik
H
Strasser
Daniel S
DS
Schwardt
Oliver
O
Kelm
Soerge
S
Ernst
Beat
B
D001665:Binding Sites; D020650:Combinatorial Chemistry Techniques; D004353:Drug Evaluation, Preclinical; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D018992:Myelin-Associated Glycoprotein / Q000737:chemistry
D008024:Ligands; D018992:Myelin-Associated Glycoprotein