title: Olfactory sensitivity for sperm-attractant aromatic aldehydes: a comparative study in human subjects and spider monkeys.
abstract: Using a three-alternative forced-choice ascending staircase procedure, we determined olfactory detection thresholds in 20 human subjects for seven aromatic aldehydes and compared them to those of four spider monkeys tested in parallel using an operant conditioning paradigm. With all seven odorants, both species detected concentrations <1 ppm, and with several odorants single individuals of both species even discriminated concentrations <1 ppb from the solvent. No generalizable species differences in olfactory sensitivity were found despite marked differences in neuroanatomical and genetic features. The across-odorant patterns of sensitivity correlated significantly between humans and spider monkeys, and both species were more sensitive to bourgeonal than to lilial, cyclamal, canthoxal, helional, lyral, and 3-phenylpropanal. No significant correlation between presence/absence of an oxygen-containing moiety attached to the benzene ring or presence/absence of an additional alkyl group next to the functional aldehyde group, and olfactory sensitivity was found in any of the species. However, the presence of a tertiary butyl group in para position (relative to the functional aldehyde group) combined with a lack of an additional alkyl group next to the functional aldehyde group may be responsible for the finding that both species were most sensitive to bourgeonal.
authors.affiliation: IFM Biology, Linköping University, Linköping, Sweden.
authors.forename: Luna
authors.initials: L
authors.lastname: Kjeldmand
authors.forename: Laura Teresa Hernandez
authors.initials: LT
authors.lastname: Salazar
authors.forename: Matthias
authors.initials: M
authors.lastname: Laska
mesh_terms: D000328:Adult; D000447:Aldehydes / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D053819:Atelinae; D001522:Behavior, Animal / Q000187:drug effects; D002755:Choice Behavior / Q000187:drug effects / Q000502:physiology; D003216:Conditioning, Operant / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D009812:Odorants; D055696:Olfactory Perception / Q000187:drug effects / Q000502:physiology*; D012684:Sensory Thresholds / Q000187:drug effects / Q000502:physiology*; D012903:Smell / Q000187:drug effects / Q000502:physiology*; D055815:Young Adult
chemical_list: D000447:Aldehydes
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