title: Molecular spectroscopic analysis of nano-chitosan blend as biosensor.
abstract: Chitosan/starch and chitosan/gelatin of different ratios were prepared following casting method. FTIR results indicate the formation of hydrogen bonding which dedicates the prepared blends for interaction with wide range of molecules specially those of NH₂ and COOH terminals. The results obtained with molecular modeling PM3 model are in agreement with spectroscopic data. As a result of increasing starch and gelatin in chitosan blends HOMO-LUMO energy slightly decreased while total dipole moment increased. UV-vis spectroscopy indicated the suitability of chitosan/starch blend as a glycine sensor. Further enhancement in the sensing performance of chitosan/starch blend was achieved by introducing 5 nm TiO₂ into the blend.
authors.affiliation: Spectroscopy Department, National Research Centre, Cairo, Egypt. medahmed6@yahoo.com
authors.forename: Medhat
authors.initials: M
authors.lastname: Ibrahim
authors.forename: Abdel Aziz
authors.initials: AA
authors.lastname: Mahmoud
authors.forename: Osama
authors.initials: O
authors.lastname: Osman
authors.forename: Ahmed
authors.initials: A
authors.lastname: Refaat
authors.forename: El-Sayed M
authors.initials: el-SM
authors.lastname: El-Sayed
mesh_terms: D000588:Amines / Q000032:analysis; D015374:Biosensing Techniques / Q000379:methods*; D002264:Carboxylic Acids / Q000032:analysis; D048271:Chitosan / Q000737:chemistry*; D005780:Gelatin / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D013057:Spectrum Analysis; D013213:Starch / Q000737:chemistry; D014025:Titanium
chemical_list: D000588:Amines; D002264:Carboxylic Acids; C009495:titanium dioxide; D005780:Gelatin; D013213:Starch; D048271:Chitosan; D014025:Titanium