Complementary PCAF-coenzyme A mutagenesis: chemoenzymatic synthesis of a novel enlarged coenzyme A analogue and evaluation of its biological activity.
Khim
Leang
L
University of Nottingham, School of Biomedical Sciences, Nottingham, NG7 2UH, UK.
Han
Juan
J
Willetts
Lynsey
L
Brady
Kevin
K
Gillece
Pauline
P
Rached
Ouannassa
O
Thomas
Neil R
NR
Stylianou
Eleni
E
D000214:Acyl Coenzyme A / Q000096:biosynthesis / Q000737:chemistry*; D019943:Amino Acid Substitution; D001665:Binding Sites; D003198:Computer Simulation; D007700:Kinetics; D016297:Mutagenesis, Site-Directed; D009713:Nucleotidyltransferases / Q000378:metabolism; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000378:metabolism; D017434:Protein Structure, Tertiary; D013379:Substrate Specificity; D050880:p300-CBP Transcription Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D000099224:p300-CBP-Associated Factor
D000214:Acyl Coenzyme A; D009713:Nucleotidyltransferases; D017853:Phosphotransferases (Alcohol Group Acceptor); D050880:p300-CBP Transcription Factors; D000099224:p300-CBP-Associated Factor; C555403:acetyl 3''-O-benzyl-coenzyme A; C020021:dephospho-CoA kinase; C022315:pantetheine-phosphate adenylyltransferase