Combined reperfusion strategies in ST-segment elevation MI: Rationale and current role.
Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation myocardial infarction (MI), but most patients do not arrive at a PCI facility within the recommended 90 minutes of first medical contact. If delay is expected, timely thrombolysis is recommended, followed by early transfer for PCI. The authors review the rationale behind three combined reperfusion strategies-facilitated PCI, pharmacoinvasive therapy, and rescue PCI-and data on their effectiveness.
Hanna
Elias B
EB
Department of Medicine, Cardiovascular Section, Louisiana State University, New Orleans, LA 70112, USA. ehanna10@yahoo.com
Hennebry
Thomas A
TA
Abu-Fadel
Mazen S
MS
D015906:Angioplasty, Balloon, Coronary; D003131:Combined Modality Therapy; D004562:Electrocardiography; D004638:Emergency Treatment; D006801:Humans; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D015425:Myocardial Reperfusion / Q000379:methods*; D010360:Patient Transfer; D016032:Randomized Controlled Trials as Topic; D012770:Shock, Cardiogenic / Q000628:therapy; D015996:Survival Rate; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome