title: Desquamative interstitial pneumonia as the initial manifestation of systemic sclerosis.
abstract: Interstitial lung disease (ILD) is a frequent pulmonary complication of systemic sclerosis (SSc), and nonspecific interstitial pneumonia is the most commonly recognized pattern of lung injury in these patients. In this report, we describe a never-smoker female presenting with Raynaud phenomenon and ILD that demonstrated desquamative interstitial pneumonia (DIP) on surgical lung biopsy. After 8 months, she was diagnosed with pulmonary hypertension at which time clinical examinations and serologic findings established the diagnosis of SSc. This case report expands the spectrum of patterns of ILD seen in association with SSc to include DIP.
authors.affiliation: Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
authors.forename: Justin S
authors.initials: JS
authors.lastname: Swartz
authors.forename: Soumya
authors.initials: S
authors.lastname: Chatterjee
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Parambil
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones