Anterior insula activity predicts the influence of positively framed messages on decision making.
The neural mechanisms underlying the influence of persuasive messages on decision making are largely unknown. We address this issue using event-related fMRI to investigate how informative messages alter risk appraisal during choice. Participants performed the Iowa Gambling Task while viewing a positively framed, negatively framed, or control message about the options. The right anterior insula correlated with improvement in choice behavior due to the positively framed but not the negatively framed message. With the positively framed message, there was increased activation proportional to message effectiveness when less-preferred options were chosen, consistent with a role in the prediction of adverse outcomes. In addition, the dorsomedial and the left dorsolateral prefrontal cortex correlated with overall decision quality, regardless of message type. The dorsomedial region mediated the relationship between the right anterior insula and decision quality with the positively framed messages. These findings suggest a network of frontal brain regions that integrate informative messages into the evaluation of options during decision making. Supplemental procedures and results for this article may be downloaded from http://cabn.psychonomic-journals.org/content/supplemental.
Krawitz
Adam
A
Indiana University, Bloomington, Indiana, USA.
Fukunaga
Rena
R
Brown
Joshua W
JW
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D002755:Choice Behavior / Q000502:physiology; D003657:Decision Making / Q000502:physiology*; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D005715:Gambling / Q000523:psychology; D005717:Games, Experimental; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010565:Persuasive Communication; D018570:Risk Assessment; D012309:Risk-Taking; D035501:Uncertainty; D055815:Young Adult
Cereb Cortex. 2009 May;19(5):1134-43
18787233
Neuroimage. 2005 Jan 1;24(1):253-9
15588617
Cogn Affect Behav Neurosci. 2007 Dec;7(4):266-77
18189000
Science. 2000 Jun 9;288(5472):1835-8
10846167
Neurosci Biobehav Rev. 2006;30(2):239-71
16197997
Neuron. 2008 Sep 25;59(6):1037-50
18817740
Soc Cogn Affect Neurosci. 2008 Dec;3(4):353-66
19015077
J Health Commun. 2007 Oct-Nov;12(7):623-44
17934940
Neuroimage. 2009 May 15;46(1):87-104
19457397
Psychol Sci. 2000 Jan;11(1):1-6
11228836
Hum Brain Mapp. 2006 Jul;27(7):572-87
16372256
Nicotine Tob Res. 2008 Jan;10(1):195-200
18188760
Nat Rev Neurosci. 2002 Aug;3(8):655-66
12154366
Psychon Bull Rev. 1994 Dec;1(4):476-90
24203555
Science. 1997 Feb 28;275(5304):1293-5
9036851
Neuroimage. 2007 Feb 15;34(4):1744-53
17175173
Psychol Bull. 2001 Mar;127(2):267-86
11316014
Psychol Bull. 1997 Jan;121(1):3-19
9000890
Hum Brain Mapp. 2000 Jul;10(3):120-31
10912591
Behav Brain Funct. 2007 Mar 15;3:16
17362508
J Neurosci. 2006 May 3;26(18):4769-73
16672649
Neuropsychologia. 2001;39(4):376-89
11164876
Behav Brain Funct. 2007 Aug 06;3:37
17683599
Neuron. 2005 Sep 1;47(5):763-70
16129404
Neuroimage. 2002 Jan;15(1):273-89
11771995
J Comp Neurol. 1989 Aug 15;286(3):353-75
2768563
Perspect Psychol Sci. 2009 May;4(3):299-307
26158967
Health Psychol. 2004 May;23(3):330-4
15099176
Neuron. 2004 Oct 14;44(2):379-87
15473974
J Pers Soc Psychol. 1986 Dec;51(6):1173-82
3806354
J Neurosci. 2008 Mar 12;28(11):2745-52
18337404
Brain Res. 2008 Apr 2;1202:99-108
17707352
Nat Neurosci. 2007 Sep;10(9):1214-21
17676057
Cognition. 1994 Apr-Jun;50(1-3):7-15
8039375
Behav Brain Funct. 2008 Mar 19;4:13
18353176
Psychol Methods. 2001 Jun;6(2):115-34
11411437
Science. 2005 Feb 18;307(5712):1118-21
15718473
Neuroimage. 2006 Apr 1;30(2):668-77
16321546
Annu Rev Neurosci. 2001;24:167-202
11283309
Hum Brain Mapp. 1999;8(2-3):109-14
10524601
Neuron. 2006 Aug 3;51(3):381-90
16880132
Front Behav Neurosci. 2009 May 18;3:6
19503749
Brain Res Cogn Brain Res. 2005 Apr;23(1):119-36
15795139
Arch Gen Psychiatry. 2005 Jul;62(7):761-8
15997017
BMC Neurosci. 2008 Jul 26;9:72
18655719
Ann N Y Acad Sci. 2008 Apr;1128:41-52
18469213
Science. 2004 Feb 13;303(5660):1023-6
14963333
Neuroimage. 2003 Aug;19(4):1439-48
12948701
Science. 2006 Aug 4;313(5787):684-7
16888142
Science. 1981 Jan 30;211(4481):453-8
7455683