A lubrication analysis of pharyngeal peristalsis: application to flavour release.
After eating a liquid or a semi-liquid food product, a thin film responsible for the dynamic profile of aroma release coats the pharyngeal mucosa. The aim of this article was to analyse the fluid mechanics of pharyngeal peristalsis and to develop a simple biomechanical model in order to understand the role of saliva and food bolus viscosity on the coating of pharyngeal mucosa. We began by analysing the physiology and the biomechanics of swallowing in order to determine relevant model assumptions. This analysis of the literature clarified the types of mechanical solicitations applied on the food bolus. Moreover, we showed that the pharyngeal peristalsis in the most occluded region is equivalent to a forward roll coating process, the originality of which is lubrication by a film of saliva. A model based on the lubrication theory for Newtonian liquids was developed in dimensionless form. The parametric study showed the strong influence of relative saliva thickness on the food bolus coating. A specific experimental device was designed that confirms the model predictions. Two sets of conditions that depend on the relative thickness of saliva were distinguished. The first is characterised by a relatively thin film of saliva: food bolus viscosity has a strong impact on mucosa coating. These phenomena are well represented by the model developed here. The second is obtained when the saliva film is relatively thick: hydrodynamic mixing with saliva, interdiffusion or instabilities may govern mucosa coating. Finally, these results were extrapolated to determine the influence of food bolus viscosity on the dynamic profile of flavour release according to physiological parameters.
de Loubens
Clément
C
INRA, UMR 782 Génie et Microbiologie des Procédés Alimentaires, CBAI, 78850 Thiverval Grignon, France. cdeloubens@grignon.inra.fr
Magnin
Albert
A
Verin
Eric
E
Doyennette
Marion
M
Tréléa
Ioan Cristian
IC
Souchon
Isabelle
I
D000465:Algorithms; D001696:Biomechanical Phenomena; D003679:Deglutition / Q000502:physiology; D005502:Food; D005947:Glucose / Q000378:metabolism; D006801:Humans; D057446:Hydrodynamics; D008954:Models, Biological; D010528:Peristalsis / Q000502:physiology*; D010614:Pharynx / Q000502:physiology*; D020545:Respiratory Mucosa / Q000502:physiology; D012212:Rheology; D012463:Saliva / Q000737:chemistry / Q000502:physiology; D013649:Taste / Q000502:physiology*; D014783:Viscosity; D014867:Water / Q000737:chemistry / Q000502:physiology
D014867:Water; D005947:Glucose