Molecular spectroscopic analysis of nano-chitosan blend as biosensor.
Chitosan/starch and chitosan/gelatin of different ratios were prepared following casting method. FTIR results indicate the formation of hydrogen bonding which dedicates the prepared blends for interaction with wide range of molecules specially those of NH₂ and COOH terminals. The results obtained with molecular modeling PM3 model are in agreement with spectroscopic data. As a result of increasing starch and gelatin in chitosan blends HOMO-LUMO energy slightly decreased while total dipole moment increased. UV-vis spectroscopy indicated the suitability of chitosan/starch blend as a glycine sensor. Further enhancement in the sensing performance of chitosan/starch blend was achieved by introducing 5 nm TiO₂ into the blend.
Ibrahim
Medhat
M
Spectroscopy Department, National Research Centre, Cairo, Egypt. medahmed6@yahoo.com
Mahmoud
Abdel Aziz
AA
Osman
Osama
O
Refaat
Ahmed
A
El-Sayed
El-Sayed M
el-SM
D000588:Amines / Q000032:analysis; D015374:Biosensing Techniques / Q000379:methods*; D002264:Carboxylic Acids / Q000032:analysis; D048271:Chitosan / Q000737:chemistry*; D005780:Gelatin / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D013057:Spectrum Analysis; D013213:Starch / Q000737:chemistry; D014025:Titanium
D000588:Amines; D002264:Carboxylic Acids; C009495:titanium dioxide; D005780:Gelatin; D013213:Starch; D048271:Chitosan; D014025:Titanium