title: Evidence-based medicine: facts and controversies.
abstract: Evidence-based medicine is a paradigm shift in the biomedical field toward scientific-based clinical practice. It is recognized as the process of acquiring and applying into practice the best available research findings in a defined filed. Although the roots of evidenced-based medicine date back more than 150 years, the modern evidenced-based medicine concept has been rapidly and constantly developing in the past two decades. Since its introduction, evidenced-based medicine has simultaneously attracted proponents and critics. This contribution provides a critical overview of the major advantages and drawbacks of evidenced-based medicine. The discussion and the examples cover the field of biomedical research and dermatovenereology in particular.
authors.affiliation: Department of Dermatology and Venereology, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Razvigor Borislavov
authors.initials: RB
authors.lastname: Darlenski
authors.forename: Neyko Valentinov
authors.initials: NV
authors.lastname: Neykov
authors.forename: Vitan Dakov
authors.initials: VD
authors.lastname: Vlahov
authors.forename: Nikolaï Konstantinov
authors.initials: NK
authors.lastname: Tsankov
mesh_terms: D016265:Conflict of Interest; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic; D035583:Rare Diseases / Q000175:diagnosis / Q000188:drug therapy*; D012871:Skin Diseases / Q000175:diagnosis / Q000188:drug therapy*