title: Calibrated real-time control of lesion size based on reflectance images.
abstract: Lesion size induced by laser photocoagulation is controlled in real time based on a two-dimensional reflectance image recorded by a CCD array during lesion formation. A feedback system using components of the reflectance image achieves uniform lesions by compensating for light absorption variability in biological media. Lesions are formed in a phantom by an argon laser to simulate retinal photocoagulation. The tissue model consists of a thin absorptive layer covered by a clear albumin protein layer. Results show a low variance in the sizes of the lesions (diameter or depth) produced in different irradiation conditions and the ability to produce lesions of a predefined size in varying illumination conditions.
authors.forename: M R
authors.initials: MR
authors.lastname: Jerath
authors.forename: D
authors.initials: D
authors.lastname: Kaisig
authors.forename: H
authors.initials: H
authors.lastname: Grady Rylander Iii
authors.forename: A J
authors.initials: AJ
authors.lastname: Welch