Introduction to genetics and childhood obesity: relevance to nursing practice.
OBJECTIVE
The aims for this article are to provide an overview of the current state of research on genetic contributions to the development of childhood obesity and to suggest genetic-focused nursing practices to prevent childhood obesity.


BACKGROUND
Genetic epidemiology of childhood obesity, modes to identifying obesity genes, types of human obesity genes, and nursing implications are discussed.


CONCLUSIONS
The successful integration of genetics into nursing practice will provide opportunities for nurses to participate fully as major agents and collaborators in the health care revolution.


CONCLUSIONS
Practicing nurses across the profession will need to become knowledgeable about genetics and take part in obesity prevention through genetic assessment of susceptibility and appropriate environmental interventions.
Seal
Nuananong
N
University of North Dakota, 430 Oxford Street, Grand Forks, ND 58202, USA. lekseal@mail.und.edu
D002648:Child; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease / Q000453:epidemiology; D006801:Humans; D009765:Obesity / Q000453:epidemiology / Q000235:genetics* / Q000451:nursing*; D010371:Pediatric Nursing / Q000379:methods*
PLoS Genet. 2007 Jul;3(7):e115
17658951
JAMA. 1986 Jul 4;256(1):51-4
3712713
Dimens Crit Care Nurs. 2002 Mar-Apr;21(2):50-60; quiz 60-1
11949469
Nat Genet. 2003 Feb;33(2):177-82
12524541
JAMA. 2003 Apr 9;289(14):1813-9
12684360
Annu Rev Med. 2005;56:443-58
15660521
Nat Med. 2002 Jul;8(7):643-4
12091883
Hum Mutat. 2003 Oct;22(4):261-74
12955713
Curr Mol Med. 2003 Jun;3(4):325-40
12776988
Nutr Rev. 2008 Dec;66(12):684-94
19019037
Nature. 2006 Nov 23;444(7118):444-54
17122850
Pediatr Res. 2003 May;53(5):721-5
12621112
N Engl J Med. 1990 May 24;322(21):1483-7
2336075
Obes Res. 2001 Nov;9 Suppl 4:239S-243S
11707548
BMJ. 1989 Jan 14;298(6666):87-90
2493303
N Engl J Med. 1986 Jan 23;314(4):193-8
3941707
Behav Genet. 1997 Jul;27(4):325-51
9519560
Clin Genet. 2004 Aug;66(2):83-93
15253756
Science. 2007 May 11;316(5826):889-94
17434869
Eur J Hum Genet. 2010 Jan;18(1):104-10
19584900
Obes Rev. 2008 May;9(3):246-50
18373508
Nature. 2000 Apr 6;404(6778):644-51
10766251
Br J Clin Pharmacol. 2001 Nov;52(5):489-99
11736857
Proc Nutr Soc. 2005 May;64(2):133-42
15960858
Pediatrics. 2003 Aug;112(2):424-30
12897303
Nat Genet. 1998 Oct;20(2):113-4
9771699
PLoS Genet. 2006 Dec 29;2(12):e188
17196040
Am Fam Physician. 2005 Aug 1;72(3):441-8
16100858
Obesity (Silver Spring). 2006 Apr;14(4):529-644
16741264
Obesity (Silver Spring). 2009 Feb;17(2):209-10
19169219
Epidemiol Rev. 2007;29:49-61
17566051
Curr Opin Genet Dev. 1998 Jun;8(3):334-42
9691003
Nature. 1997 Jun 26;387(6636):903-8
9202122
Nat Genet. 2007 Jun;39(6):724-6
17496892
Endocrinology. 2003 Sep;144(9):3757-64
12933645
Ann Acad Med Singap. 2009 Jan;38(1):75-7
19221674
Science. 2006 Apr 14;312(5771):279-83
16614226
Nat Rev Genet. 2005 Mar;6(3):221-34
15703762
J Clin Endocrinol Metab. 2005 Mar;90(3):1871-87
15598688
Nat Genet. 1997 Jul;16(3):303-6
9207799
Nat Genet. 1998 Jun;19(2):155-7
9620771
Obes Facts. 2008;1(1):35-42
20054160
Am J Hum Genet. 2000 Oct;67(4):881-900
10986041
Circulation. 2005 Apr 19;111(15):1999-2012
15837955
Am J Clin Nutr. 2005 Jul;82(1 Suppl):215S-217S
16002823