title: Down syndrome: a risk factor for mycotic aneurysm?
abstract: Down syndrome, or trisomy 21, has a characteristic constellation of clinical findings, including various congenital heart defects. We report a case of an adult male with Down syndrome who presented with a 3-week history of lower limb pain and swelling, attributed to cellulitis. Clinical and angiographic evaluation identified a below-knee mycotic pseudoaneurysm secondary to infective endocarditis. Surgical aneurysmal repair and revascularization were performed. Various management options are outlined in this report.
authors.affiliation: Department of Vascular Surgery, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Naughton
authors.forename: Tim T
authors.initials: TT
authors.lastname: Wang
authors.forename: Aoife N
authors.initials: AN
authors.lastname: Keeling
authors.forename: Darragh
authors.initials: D
authors.lastname: Moneley
authors.forename: Cathal J
authors.initials: CJ
authors.lastname: Kelly
mesh_terms: D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D015901:Angiography, Digital Subtraction; D004314:Down Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D004696:Endocarditis / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation; D016909:Tibial Arteries / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome