title: >400 kHz repetition rate wavelength-swept laser and application to high-speed optical frequency domain imaging.
abstract: We demonstrate a high-speed wavelength-swept laser with a tuning range of 104 nm (1228-1332 nm) and a repetition rate of 403 kHz. The design of the laser utilizes a high-finesse polygon-based wavelength-scanning filter and a short-length unidirectional ring resonator. Optical frequency domain imaging of the human skin in vivo is presented using this laser, and the system shows sensitivity of higher than 98 dB with single-side ranging depth of 1.7 mm over 4 dB sensitivity roll-off.
authors.affiliation: Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 704, Boston, Massachusetts 02114, USA. woh1@kaist.ac.kr
authors.forename: Wang-Yuhl
authors.initials: WY
authors.lastname: Oh
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Vakoc
authors.forename: Milen
authors.initials: M
authors.lastname: Shishkov
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Tearney
authors.forename: Brett E
authors.initials: BE
authors.lastname: Bouma
mesh_terms: D006801:Humans; D007834:Lasers; D057054:Molecular Imaging / Q000379:methods*; D055620:Optical Phenomena; D012867:Skin; D013997:Time Factors
references.citation: IEEE Photonics Technol Lett. 2004 Jan;16(1):293-295
references.pmid: 20640193
references.citation: Opt Express. 2003 Apr 21;11(8):889-94
references.pmid: 19461802
references.citation: JACC Cardiovasc Imaging. 2008 Nov;1(6):752-61
references.pmid: 19356512
references.citation: Nat Med. 2006 Dec;12(12):1429-33
references.pmid: 17115049
references.citation: Opt Lett. 2003 Oct 15;28(20):1981-3
references.pmid: 14587796
references.citation: Opt Lett. 2005 Dec 1;30(23):3159-61
references.pmid: 16350273
references.citation: Opt Express. 2003 Nov 3;11(22):2953-63
references.pmid: 19471415
references.citation: Opt Express. 2006 Apr 17;14(8):3225-37
references.pmid: 19516464
references.citation: Opt Lett. 2006 Oct 15;31(20):2975-7
references.pmid: 17001371
references.citation: Gastrointest Endosc. 2008 Oct;68(4):745-53
references.pmid: 18926183
references.citation: Opt Lett. 2003 Nov 1;28(21):2067-9
references.pmid: 14587817
references.citation: Opt Express. 2003 Sep 8;11(18):2183-9
references.pmid: 19466106