Rhodium-catalyzed asymmetric arylation of N-tosyl ketimines.
A rhodium-catalyzed addition of sodium tetraarylborates to N-tosyl ketimines is described. Highly efficient asymmetric catalysis has been achieved by employing a chiral diene ligand, constructing chiral amine derivatives possessing α-tetrasubstituted carbon stereocenters with high enantioselectivity.
Shintani
Ryo
R
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. shintani@kuchem.kyoto-u.ac.jp
Takeda
Momotaro
M
Tsuji
Takaoki
T
Hayashi
Tamio
T