[Toxicity and toxin profile of the dinoflagellate Alexandrium tamiyavanichii and toxic mussels in Harima-Nada of Seto Inland Sea, Japan].
From October to November 2004, the paralytic shellfish poison (PSP)-producing dinoflagellate Alexandrium tamiyavanichii was observed at Harima-Nada, Seto Inland Sea at a maximum cell density of 4,960 cells/L. The wild cells of the dinoflagellate collected from the same seawaters, and cultured cells derived from them showed toxicity scores of 6.25-15.4 x 10(-4) and 2.7-3.5 x 10(-4) MU/cell, respectively, both of which were much higher than those of previously reported strains. PSP of the wild cells was mainly composed of gonyautoxin (GTX) 5 (40.6-52.4 mol%) and GTX4 (15.6-24.8 mol%), showing a unique composition that was greatly different from those of the previously reported strains, or of the cultured cells, whose main toxin component was GTX3 (average 37.6 mol%). The mussel Mytilus galloprovincialis collected from the same area in the same period accumulated a relatively high level of PSP (13-28 MU/g), suggesting a risk that A. tamiyavanichii may induce high-level PSP contamination of bivalves even at a cell density as low as around 5,000 cells/L.
Sagara
Takefumi
T
Department of Science for Living, Shikoku University, Junior College, Tokushima, Japan.
Taniyama
Shigeto
S
Yoshimatsu
Sadaaki
S
Takatani
Tomohiro
T
Hashimoto
Tamiko
T
Nishibori
Naoyoshi
N
Nishio
Sachio
S
Arakawa
Osamu
O
D000818:Animals; D000832:Animals, Poisonous; D049872:Bivalvia / Q000737:chemistry*; D004141:Dinoflagellida / Q000737:chemistry*; D007564:Japan; D008387:Marine Toxins / Q000032:analysis* / Q000633:toxicity; D051379:Mice; D012530:Saxitoxin / Q000031:analogs & derivatives / Q000032:analysis
D008387:Marine Toxins; D012530:Saxitoxin; C013007:gonyautoxins