Detection of Hodgkin lymphoma within ovarian tissue.
OBJECTIVE
To describe the detection of Hodgkin lymphoma within ovarian tissue taken at the time of harvest for cryopreservation.


METHODS
Case report.


METHODS
University-affiliated women's hospital.


METHODS
A 19-year-old woman diagnosed with Hodgkin lymphoma.


METHODS
Laparoscopic removal of ovarian tissue for cryopreservation.


METHODS
Histologic and immunohistochemical evaluation of ovarian tissue harvested for fertility preservation.


RESULTS
Histologic and immunohistochemical identification of Hodgkin lymphoma within ovarian tissue harvested for cryopreservation.


CONCLUSIONS
Ovarian cryopreservation and subsequent autografting is a procedure still in an experimental phase that has yielded promising findings. This option is frequently offered to young women with neoplasms such as Hodgkin lymphoma. Although the risk of Hodgkin lymphoma infiltration into the ovary may be low, the identification of lymphoma in this case emphasizes the importance of histologic examination of ovarian tissue before freezing and indicates that there is a possibility of reintroducing tumor.
Bittinger
Sophie E
SE
Department of Anatomical Pathology, Royal Women's Hospital, Parkville, Victoria, Australia.
Nazaretian
Simon P
SP
Gook
Debra A
DA
Parmar
Chandrika
C
Harrup
Rosemary A
RA
Stern
Catharyn J
CJ
D015925:Cryopreservation; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control; D010535:Laparoscopy; D008207:Lymphatic Metastasis; D054315:Oocyte Retrieval; D009865:Oocytes; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary / Q000601:surgery; D010053:Ovary / Q000473:pathology*; D055815:Young Adult