[Extended-spectrum beta-lactamase producing-enterobacteriaceae].
Extended-spectrum beta-lactamase (ESBLs) are defined as β-lactamase capable of hydrolyzine oximino-cephalosporins and aztreonam and are encoded by mobile genes. The most frequently encountered ESBLs belong to the CTX-M, SHV, and TEM families. ESBLs were found first in Klebsiella pneumonia and then predominantly in E. coli. The incidence of patients with ESBLs E. coli increase since 2000 in Robert Debré Hospital. They were responsible of cystitis or pyelopnephritis and rarely of materno-foetal infections or neonatal meningitis. These strains were susceptible to colimycin, carbapenems and fosfomycin.
Doit
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Service de bactériologie, Université Paris-Diderot, Hôpital Robert Debré, 48, Boulevard Sérurier, 75935 Paris cedex 19, France.
Mariani-Kurkdjian
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Bingen
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D001426:Bacterial Proteins / Q000235:genetics; D002648:Child; D004755:Enterobacteriaceae / Q000201:enzymology / Q000235:genetics*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000635:transmission; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D004927:Escherichia coli Infections / Q000453:epidemiology; D014943:Global Health; D006801:Humans; D007231:Infant, Newborn; D016920:Meningitis, Bacterial / Q000453:epidemiology / Q000401:mortality; D001618:beta-Lactamases / Q000235:genetics*
D001426:Bacterial Proteins; D001618:beta-Lactamases