Structure and procedures of the pharmacy and therapeutic committees in Spanish hospitals.
OBJECTIVE
Define the structure and working procedures of the Pharmacy and Therapeutic Committees (P&T Committees) in Spanish hospitals.


METHODS
Hospitals over 75 beds located in all regions of the Spanish State.


METHODS
A cross-sectional descriptive study based on the completion of a questionnaire that consisted of 138 questions. The participants were recruited by post, e-mail and telephone between November 2007 and January 2008. The Hospitals were classified according to their size and public or private and university or non-university status.


METHODS
They are related with the structure and composition of the P&T Committees, performance, drug evaluation process, working methods and the results of their activity.


RESULTS
A total of 200 hospitals answered the questionnaire (response rate of 39.0% of hospitals and 57.1% of the beds in Spain). All the hospitals have P&T Committees, 99.5% have a Drug Formulary, 71.0% have a Therapeutic Interchange Programme and 91.0% have a document determining the mission, objectives and functions of the P&T Committee. Almost all hospitals (95.5%) have established a formal application for the inclusion of a drug in the hospital, while 80.5% have established a model for evaluation reports. The mean (SD) number of participants in P&T Committees was 11.84 (3.82). The annual mean of drugs evaluated per hospital was 10.35 (7.45). The proportion of assessments that concludes the inclusion, rejection or deferral of the decision was 75.3, 21.4 and 3.2%, respectively.


CONCLUSIONS
Spanish P&T Committees have a similar structure and function, a multi-disciplinary professional composition to carry out an important assessment activity. This activity is higher in large hospitals and in university hospitals. The proportion of the approved and rejected drugs is similar in different types of hospital. The Therapeutic Interchange Guidelines, the use of application models and the reports follow the indications of scientific collaborative groups, thus being used more in Spain than in other countries.
Puigventós
Francesc
F
Pharmacy Department, Hospital Universitario Son Dureta, C/ Andrea Doria nº. 55, 07014, Palma de Mallorca, Spain. francesc.puigventos@ssib.es
Santos-Ramos
Bernardo
B
Ortega
Ana
A
Durán-García
Esther
E
D003430:Cross-Sectional Studies; D006761:Hospitals; D006801:Humans; D010607:Pharmacy Service, Hospital / Q000379:methods / Q000458:organization & administration*; D010606:Pharmacy and Therapeutics Committee / Q000458:organization & administration*; D010865:Pilot Projects; D013030:Spain; D011795:Surveys and Questionnaires
Farm Hosp. 2007 Jul-Aug;31(4):212-7
18052615
Eur J Clin Pharmacol. 2008 Mar;64(3):319-27
18038228
Am J Health Syst Pharm. 2005 Feb 15;62(4):378-90
15745890
Can J Cardiol. 2003 Feb;19(2):173-9
12601443
Rev Clin Esp. 2000 May;200(5):261-70
10901004
Am J Health Syst Pharm. 2001 Dec 1;58(23):2251-66
11763804
Br J Clin Pharmacol. 1999 Aug;48(2):239-46
10417503
Farm Hosp. 2009 Mar-Apr;33(2):66-71
19480793
Can J Clin Pharmacol. 2009 Winter;16(1):e171-7
19242000
Pharmacotherapy. 2005 Nov;25(11):1666-80
16232030
Eur J Clin Pharmacol. 1997;52(6):429-35
9342577
Am J Health Syst Pharm. 2005 Feb 1;62(3):321-4
15719594
Farm Hosp. 2004 Nov-Dec;28(6):426-32
15628945
Pharm World Sci. 2007 Apr;29(2):90-6
17187221
Farm Hosp. 2004 Jul-Aug;28(4):266-74
15369437
Am J Health Syst Pharm. 2005 Jan 15;62(2):189-95
15700893
Value Health. 2003 Sep-Oct;6(5):505-21
14627057
Am J Health Syst Pharm. 1999 Apr 1;56(7):622-8
10423208
Farm Hosp. 2005 Mar;29(2):104-12
16013932
Farm Hosp. 2003 Sep-Oct;27(5):290-7
14576918
Am J Health Syst Pharm. 2008 Jul 1;65(13):1272-83
18589893