title: Serum albumin and biomolecular oxidative damage of human atherosclerotic plaques.
abstract: OBJECTIVE
  To investigate the association of serum albumin (SA) with oxidative damage of human atherosclerotic plaques and the severity of atherosclerosis.
  
  
  METHODS
  Correlation of the levels of SA with those of lipid and protein oxidation of endarterectomy-removed carotid atherosclerotic plaques; SA and plaque oxidative biomarkers comparison between 2 groups of patients with different severity of atherosclerotic carotid stenosis, i.e. <90% (group I) or ≥90% (group II).
  
  
  RESULTS
  SA was strongly inversely correlated with plaque oxidative damage; SA was lower and plaque oxidative damage higher in group II than group I.
  
  
  CONCLUSIONS
  Lowered SA is associated with oxidative damage of atherosclerotic plaques and the severity of atherosclerosis.
authors.affiliation: Dipartimento di Medicina e Scienze dell'Invecchiamento, Università G. d'Annunzio, Italy. dlapenna@unich.it
authors.forename: Domenico
authors.initials: D
authors.lastname: Lapenna
authors.forename: Giuliano
authors.initials: G
authors.lastname: Ciofani
authors.forename: Sante
authors.initials: S
authors.lastname: Ucchino
authors.forename: Sante Donato
authors.initials: SD
authors.lastname: Pierdomenico
authors.forename: Chiara
authors.initials: C
authors.lastname: Cuccurullo
authors.forename: Maria Adele
authors.initials: MA
authors.lastname: Giamberardino
authors.forename: Franco
authors.initials: F
authors.lastname: Cuccurullo
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000097:blood* / Q000473:pathology*; D015415:Biomarkers / Q000378:metabolism; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction; D058226:Plaque, Atherosclerotic / Q000378:metabolism / Q000473:pathology*; D012709:Serum Albumin / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D012709:Serum Albumin