Noroviruses - State of the Art.
Noroviruses are a common cause of both endemic and epidemic gastroenteritis. These highly infectious viruses usually cause self-limited disease, but chronic infections occur in highly immunocompromised patients and unusual manifestations are also being described in some populations. Histoblood-group antigen expression is now recognized as an important susceptibility factor for many norovirus strains, but a correlate of acquired immunity to infection or illness has not yet been identified. Currently, treatment and prevention strategies rely on non-specific measures. However, virus-like particles containing capsid antigens are undergoing evaluation as a vaccine candidate for illness prevention. This article reviews the biologic properties, epidemiology, clinical features, host susceptibility, diagnosis, and treatment and prevention of norovirus infection.
Atmar
Robert L
RL
Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, MS BCM 280, Houston, TX 77030, USA, , FAX: 713-798-6802.
J Clin Microbiol. 2010 Mar;48(3):915-20
20053852
J Clin Virol. 2009 Dec;46(4):341-4
19796988
J Perinatol. 2008 Jan;28(1):79-81
18165834
J Hosp Infect. 2010 Jan;74(1):1-9
19819586
Clin Infect Dis. 2002 Aug 1;35(3):246-53
12115089
J Med Virol. 2008 Jul;80(7):1296-301
18461617
PLoS One. 2009 Aug 24;4(8):e6671
19701458
Emerg Infect Dis. 2008 Oct;14(10):1553-7
18826818
MMWR Recomm Rep. 2001 Jun 1;50(RR-9):1-17
15580799
Gastroenterol Clin North Am. 2006 Jun;35(2):275-90, viii
16880066
Emerg Infect Dis. 2008 Aug;14(8):1224-31
18680645
Emerg Infect Dis. 2010 Jan;16(1):81-7
20031047
N Engl J Med. 1977 Jul 14;297(2):86-9
405590
J Clin Microbiol. 2004 Jul;42(7):2988-95
15243049
J Virol. 2010 Feb;84(4):1800-15
20007270
Int J Food Microbiol. 2004 Dec 15;97(2):179-86
15541804
J Gen Virol. 2007 Dec;88(Pt 12):3347-3359
18024905
J Virol. 2007 Nov;81(22):12111-8
17855555
Clin Infect Dis. 2004 Aug 1;39(3):318-24
15306997
Euro Surveill. 2005 Sep 22;10(9):E050922.2
16788235
MMWR Morb Mortal Wkly Rep. 2007 Aug 24;56(33):842-6
17717513
Clin Microbiol Rev. 2001 Jan;14(1):15-37
11148001
Clin Microbiol Infect. 2006 Jan;12(1):69-74
16460549
J Infect Dis. 2000 May;181 Suppl 2:S367-73
10804150
Trends Microbiol. 2004 Jun;12(6):279-87
15165606
Nat Med. 2003 May;9(5):548-53
12692541
Emerg Infect Dis. 2007 Aug;13(8):1184-8
17953089
J Pediatr Gastroenterol Nutr. 2005 Mar;40(3):328-33
15735487
J Infect Dis. 1994 Jul;170(1):34-43
8014518
PLoS Biol. 2004 Dec;2(12):e432
15562321
J Clin Microbiol. 2008 Dec;46(12):4011-7
18842942
J Infect Dis. 1974 Jun;129(6):709-14
4209723
Epidemiol Infect. 1993 Aug;111(1):157-62
8394241
J Infect Dis. 2008 Sep 15;198(6):941-2; author reply 942-3
18721067
J Pediatr Gastroenterol Nutr. 2009 Mar;48(3):328-33
19274789
Epidemiol Infect. 1994 Dec;113(3):513-21
7995361
Emerg Infect Dis. 2008 Feb;14(2):238-43
18258116
J Med Virol. 2008 Aug;80(8):1468-76
18551613
J Clin Microbiol. 2006 Apr;44(4):1405-12
16597869
BMC Infect Dis. 2008 Oct 22;8:143
18940017
J Virol. 2005 Jun;79(11):6714-22
15890909
J Gen Virol. 2004 Jan;85(Pt 1):79-87
14718622
J Med Virol. 1997 Dec;53(4):372-83
9407386
Virology. 2006 Mar 15;346(2):312-23
16343580
Clin Infect Dis. 2009 Apr 1;48(7):849-55
19239351
Pediatrics. 2008 Jun;121(6):e1555-62
18519460
Pediatr Transplant. 2008 May;12(3):372-5
18221419
Clin Infect Dis. 2009 Oct 1;49(7):1061-8
19705974
PLoS One. 2009;4(5):e5593
19440360
J Infect Dis. 2009 Sep 1;200(5):802-12
19627248
Clin Infect Dis. 2006 Apr 1;42(7):964-9
16511760
J Virol. 2008 Aug;82(15):7336-45
18480447
Emerg Infect Dis. 2007 Jan;13(1):144-6
17370531
Appl Environ Microbiol. 2004 Sep;70(9):5089-93
15345386
J Pediatr. 2008 Sep;153(3):339-44
18534621
Clin Vaccine Immunol. 2007 Oct;14(10):1349-55
17715333
Am J Epidemiol. 2001 Oct 1;154(7):666-74
11581101
MMWR Morb Mortal Wkly Rep. 2002 Jun 7;51(22):477-9
12064451
J Virol. 2006 Nov;80(21):10372-81
17041218
Nephrol Dial Transplant. 2009 Mar;24(3):1051-3
19073655
J Infect Dis. 2000 May;181 Suppl 2:S331-5
10804146
J Clin Virol. 2007 Sep;40(1):38-42
17631044
Virology. 2002 Aug 1;299(2):225-239
12202225
Gastroenterology. 1999 Jul;117(1):40-8
10381908
Am J Public Health. 1982 Dec;72(12):1329-32
6291414
Emerg Infect Dis. 2006 Jun;12(6):931-6
16707048
Int J Food Microbiol. 2003 Oct 15;87(1-2):107-12
12927712
Appl Environ Microbiol. 2007 Jan;73(2):581-5
17142353
Clin Immunol. 2003 Sep;108(3):241-7
14499247
Vaccine. 2006 Jun 12;24(24):5220-34
16650512
N Engl J Med. 2009 Oct 29;361(18):1776-85
19864676
J Clin Microbiol. 2007 Aug;45(8):2720-2
17537929
PLoS Med. 2008 Feb;5(2):e31
18271619
J Virol. 2008 Nov;82(21):10756-67
18701592
Appl Environ Microbiol. 2000 Jan;66(1):213-8
10618226
J Virol. 2005 Dec;79(24):15351-5
16306606
J Virol. 2003 Jan;77(1):405-15
12477845
Clin Infect Dis. 2009 Nov 1;49(9):1312-7
19814610
J Virol. 2003 Dec;77(24):13117-24
14645568
J Virol. 2005 Mar;79(5):2900-9
15709009
J Med Virol. 2005 Sep;77(1):116-20
16032732
J Infect Dis. 2002 May 1;185(9):1335-7
12001052
Clin Infect Dis. 2007 Apr 15;44(8):1032-9
17366445
Emerg Infect Dis. 2004 Oct;10(10):1827-34
15504271
J Virol. 2008 Feb;82(4):1777-86
18045944
J Clin Microbiol. 1993 Jun;31(6):1630-4
8391025