title: Minimalist end groups for control of absolute helicity in salen- and salophen-based metallofoldamers.
abstract: (S)-1-Methylindan end groups are effective controllers of absolute helicity in Ni-salen- and Ni-salophen-based foldamers derived from (R,R)-trans-1,2-cyclohexanediamine and 1,2-phenylenediamine, respectively. Evidence for the helicity of the described complexes was provided through X-ray crystallography and study of chiroptical properties in solution. The chiral end groups control the absolute sense of helicity for the salen complexes, even in a case where the helical bias of the end group is mismatched relative to that of the internal diamine.
authors.affiliation: Brown Laboratories, Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Dong
authors.forename: James N
authors.initials: JN
authors.lastname: Plampin
authors.forename: Glenn P A
authors.initials: GP
authors.lastname: Yap
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Fox