Ocular motor abnormalities in Parkinsonian syndromes.
Oculomotor abnormalities can be observed in all Parkinsonian syndromes (PS). Nevertheless, due to the considerable overlap of oculomotor pathology in Parkinsonism, oculomotor changes are not generally considered to contribute substantially to the differential diagnosis of PS. Here we review the characteristics of oculomotor disturbances in the major PS, we provide a survey of the current concepts of the underlying neural physiology of oculomotor control and a summary of the major recording techniques for eye movements. The main focus of this review is to outline the subtle differences between apparently similar oculomotor alterations in Parkinson's disease (PD) and atypical neurodegenerative PS that can contribute to the early differential diagnosis of these entities.
Pinkhardt
Elmar H
EH
Department of Neurology, University of Ulm, Oberer Eselsberg 45, Ulm, Germany.
Kassubek
Jan
J
D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000503:physiopathology