title: Asymptomatic catheter related Rhizobium radiobacter infection in a haploidentical hemapoetic stem cell recipient.
abstract: Catheter related infections are reported as one of the most common source of nosocomial infections. Rhizobium radibacter infections are generally manifested by fever and leukocytosis. Here, a 14 months-old girl diagnosed as T (-) B (-) NK (+) severe combined immunodeficiency (SCID) is presented. She had received repeated (x3) unconditioned haploidentical hematopoetic stem cell transplantations. During the follow-up, she has been arised an asymptomatic infection with R. Radiobacter, which was isolated from central venous catheter and peripheral blood while she was clinically stable, free of symptoms, fever or leukocytosis. She was treated successfully with cefepime and amikacin and did not require catheter removal. So, it is once more clear that the blood cultures should be obtained on regular basis from all patients with an intravascular device, even they were asymptomatic.
authors.affiliation: Ankara University School of Medicine, Department of Pediatric Immunology-Allergy, Ankara, Turkey. drferol@yahoo.com.tr
authors.forename: Funda
authors.initials: F
authors.lastname: Erol Cipe
authors.forename: Figen
authors.initials: F
authors.lastname: Doğu
authors.forename: Deniz
authors.initials: D
authors.lastname: Sucuoğlu
authors.forename: Derya
authors.initials: D
authors.lastname: Aysev
authors.forename: Aydan
authors.initials: A
authors.lastname: Ikincioğulları
mesh_terms: D016960:Agrobacterium tumefaciens / Q000302:isolation & purification*; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001769:Blood / Q000382:microbiology; D055499:Catheter-Related Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D002405:Catheterization, Central Venous; D057785:Catheters / Q000382:microbiology; D000077723:Cefepime; D002511:Cephalosporins / Q000627:therapeutic use; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D016511:Severe Combined Immunodeficiency / Q000150:complications* / Q000628:therapy; D033581:Stem Cell Transplantation / Q000009:adverse effects
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000077723:Cefepime; D000583:Amikacin