Seminal plasma zinc level may be associated with the effect of cigarette smoking on sperm parameters.
The aim of this study was to investigate the effect of cigarette smoking on seminal plasma zinc levels and sperm parameters, and to examine the role of seminal plasma zinc. Semen samples from 79 non-smokers and 68 smokers were obtained. There was a significant decrease in seminal plasma zinc in smokers and a clear correlation between seminal plasma zinc levels and the extent of smoking. Sperm parameters (concentration, motility and morphology) among smokers were significantly lower in comparison to non-smokers. These parameters were also significantly decreased among smokers with abnormal zinc levels, while there was no significant difference between non-smokers with normal zinc and non-smokers with abnormal zinc levels. As previous studies have shown that seminal plasma zinc is associated with a decrease of anti-oxidant defences, seminal plasma zinc could be a contributor to the effects of cigarette smoking on sperm parameters. In conclusion, cigarette smoking can affect sperm parameters and this study may help towards providing a mechanistic explanation.
Liu
R-Z
RZ
Centre for Reproductive Medicine, First Hospital, Jilin University, Changchun, China. ccrisheng2006@126.com
Gao
J-C
JC
Zhang
H-G
HG
Wang
R-X
RX
Zhang
Z-H
ZH
Liu
X-Y
XY
D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000378:metabolism; D008297:Male; D018384:Oxidative Stress; D012661:Semen / Q000737:chemistry*; D012907:Smoking / Q000009:adverse effects* / Q000378:metabolism; D013076:Sperm Count; D013081:Sperm Motility / Q000187:drug effects / Q000502:physiology; D013094:Spermatozoa / Q000187:drug effects* / Q000502:physiology; D055815:Young Adult; D015032:Zinc / Q000032:analysis*
D015032:Zinc