A reduced phytate diet does not reduce endogenous fecal zinc in children on a habitual high-phytate diet.
Ten Malawian children, ages 3 to 5 years, at risk for zinc deficiency and receiving a habitual maize-based high-phytate diet, received maize after phytate reduction for 40 days and had their endogenous fecal zinc (EFZ) measured using stable isotope techniques before and after phytate reduction. The phytate:Zn of the diet before reduction was 23.0 and afterward was 7.6. EFZ was similar before and after dietary phytate reduction, 1.15 ± 0.33 and 1.17 ± 0.16 mg/day, respectively. EFZ was not affected by dietary phytate in this population.
Kennedy
Gregg
G
Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
Hambidge
K Michael
KM
Manary
Mark
M
D002675:Child, Preschool; D004032:Diet; D002523:Edible Grain / Q000737:chemistry; D005243:Feces / Q000737:chemistry*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D008295:Malawi; D008297:Male; D010833:Phytic Acid / Q000008:administration & dosage* / Q000032:analysis; D011446:Prospective Studies; D003313:Zea mays / Q000737:chemistry*; D015032:Zinc / Q000032:analysis* / Q000172:deficiency
D010833:Phytic Acid; D015032:Zinc