[Immunophenotype of neoplastic cells and its clinical significance in chronic lymphocytic leukemia].
y We report preliminary results of efficacious clinical application of a new immunological method with the use of biochips for diagnosis of chronic lymphocytic leukemia. This method has been developed by the authors to detect a wide range of cell surface antigens. We compared the amount of cells expressing certain antigens with clinical properties of chronic lymphocytic leukemia. Higher amounts of CD9, CD21, CD31, CD71, CD38 positive lymphocytes were shown to occur in case of favorable course of the disease.
Nikitin
E N
EN
Ovchinina
N G
NG
Shishkin
A V
AV
Kir'ianov
N A
NA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015703:Antigens, CD / Q000378:metabolism; D005260:Female; D006684:HLA-DR Antigens / Q000378:metabolism; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism; D008297:Male; D008875:Middle Aged
D015703:Antigens, CD; D006684:HLA-DR Antigens