title: Role of titin in skeletal muscle function and disease.
abstract: This review covers recent developments in the titin field. Most recent reviews have discussed titin's role in cardiac function: here we will mainly focus on skeletal muscle, and discuss recent advances in the understanding of titin's role in skeletal muscle function and disease.
authors.affiliation: Department of Physiology, University of Arizona, Tucson, AZ, USA.
authors.forename: Coen A C
authors.initials: CA
authors.lastname: Ottenheijm
authors.forename: Henk
authors.initials: H
authors.lastname: Granzier
mesh_terms: D001696:Biomechanical Phenomena / Q000502:physiology; D002352:Carrier Proteins / Q000502:physiology; D064211:Connectin; D004548:Elasticity; D006801:Humans; D009124:Muscle Proteins / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D009135:Muscular Diseases / Q000503:physiopathology*; D020033:Protein Isoforms / Q000502:physiology; D011494:Protein Kinases / Q000502:physiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology; D012518:Sarcomeres / Q000502:physiology
chemical_list: D002352:Carrier Proteins; D064211:Connectin; D009124:Muscle Proteins; D020033:Protein Isoforms; C577285:TTN protein, human; D011494:Protein Kinases