Lying about the valence of affective pictures: an fMRI study.
The neural correlates of lying about affective information were studied using a functional magnetic resonance imaging (fMRI) methodology. Specifically, 13 healthy right-handed Chinese men were instructed to lie about the valence, positive or negative, of pictures selected from the International Affective Picture System (IAPS) while their brain activity was scanned by a 3T Philip Achieva scanner. The key finding is that the neural activity associated with deception is valence-related. Comparing to telling the truth, deception about the valence of the affectively positive pictures was associated with activity in the inferior frontal, cingulate, inferior parietal, precuneus, and middle temporal regions. Lying about the valence of the affectively negative pictures, on the other hand, was associated with activity in the orbital and medial frontal regions. While a clear valence-related effect on deception was observed, common neural regions were also recruited for the process of deception about the valence of the affective pictures. These regions included the lateral prefrontal and inferior parietal regions. Activity in these regions has been widely reported in fMRI studies on deception using affectively-neutral stimuli. The findings of this study reveal the effect of valence on the neural activity associated with deception. Furthermore, the data also help to illustrate the complexity of the neural mechanisms underlying deception.
Lee
Tatia M C
TM
Laboratory of Neuropsychology, The University of Hong Kong, Hong Kong, China. tmclee@hkusua.hku.hk
Lee
Tiffany M Y
TM
Raine
Adrian
A
Chan
Chetwyn C H
CC
D000328:Adult; D000339:Affect / Q000502:physiology*; D000704:Analysis of Variance; D001921:Brain / Q000502:physiology; D003116:Color; D008192:Deception; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010775:Photic Stimulation; D010781:Photography; D014342:Truth Disclosure
Neuroimage. 2005 Mar;25(1):267-77
15734361
Neuroreport. 2001 Sep 17;12(13):2849-53
11588589
Cereb Cortex. 2009 Jul;19(7):1557-66
18980948
Neuroimage. 2005 Nov 1;28(2):305-13
16165373
Hum Brain Mapp. 2002 Mar;15(3):157-64
11835606
J Clin Psychiatry. 2009 Jan;70(1):36-45
19192464
Annu Rev Psychol. 1999;50:191-214
10074678
Neuroimage. 2006 Jun;31(2):906-19
16488159
Neurosci Lett. 2008 Nov 14;445(2):135-9
18771704
Philos Trans R Soc Lond B Biol Sci. 2004 Nov 29;359(1451):1755-62
15590616
Trends Cogn Sci. 1999 Jan;3(1):11-21
10234222
J Cogn Neurosci. 2010 Feb;22(2):362-76
19199417
J Cogn Neurosci. 2007 Feb;19(2):287-95
17280517
Neuroimage. 2005 Oct 1;27(4):824-34
15982902
Cereb Cortex. 2003 Aug;13(8):830-6
12853369
Int J Geriatr Psychiatry. 2006 Sep;21(9):831-7
16955438
J Cogn Neurosci. 2002 Nov 15;14(8):1215-29
12495527
Neurosci Lett. 2002 Nov 15;333(1):13-6
12401549
Neuron. 2002 Feb 14;33(4):653-63
11856537
Cereb Cortex. 2006 Feb;16(2):192-9
15858160
Neuroreport. 1998 Oct 5;9(14):3233-9
9831457
Soc Neurosci. 2009;4(6):518-27
18633835
Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8410-3
9653200
J Am Acad Child Adolesc Psychiatry. 2000 Apr;39(4):477-84
10761350
Neurosci Lett. 2009 Jun 26;457(2):101-6
19429172
J Cogn Neurosci. 2000 May;12(3):505-19
10931775
Neuroimage. 2006 Mar;30(1):325-40
16230029
Cereb Cortex. 1996 Jan-Feb;6(1):11-20
8670634
Neuroimage. 2004 Jan;21(1):340-51
14741672
Hum Brain Mapp. 2005 Nov;26(3):199-209
15929087
Hum Brain Mapp. 2007 May;28(5):409-23
17133391
Science. 1998 Feb 27;279(5355):1347-51
9478894
Neuroimage. 2005 May 15;26(1):206-14
15862220
Biol Psychiatry. 2005 Oct 15;58(8):605-13
16185668
Curr Opin Neurol. 2009 Dec;22(6):594-600
19786872
Mol Psychiatry. 2005 May;10(5):450-5
15477872
Neuroimage. 2004 Sep;23(1):64-74
15325353
Neuroimage. 2003 Dec;20(4):1955-63
14683701
Cereb Cortex. 2008 Feb;18(2):451-5
17584853
Hum Brain Mapp. 1998;6(4):270-82
9704265
Cogn Affect Behav Neurosci. 2008 Jun;8(2):153-64
18589506
Neuroimage. 2002 Mar;15(3):727-32
11848716
Genet Soc Gen Psychol Monogr. 2006 Aug;132(3):197-214
17969998
Neuroimage. 2004 Oct;23(2):483-99
15488398
Brain Cogn. 2009 Dec;71(3):354-61
19679384
Eur Psychiatry. 2008 Jun;23(4):309-14
18029153
Brain. 2001 Oct;124(Pt 10):2074-86
11571223
Biol Psychiatry. 2003 Sep 1;54(5):504-14
12946879
Am J Psychiatry. 1997 Jul;154(7):918-25
9210741
Brain. 1999 Oct;122 ( Pt 10):1839-50
10506087
Nat Neurosci. 2000 Oct;3(10):1049-56
11017179
Neurosci Lett. 2001 Aug 24;309(2):109-12
11502357
Neuropsychologia. 1971 Mar;9(1):97-113
5146491
Hum Brain Mapp. 2005 Dec;26(4):262-72
16161128
Brain Res. 1993 Sep 3;621(1):116-20
8221062
Neuroimage. 2008 Apr 15;40(3):1411-8
18308586
Neuroimage. 2002 Jun;16(2):331-48
12030820
Acad Radiol. 2005 Feb;12(2):164-72
15721593
Brain Cogn. 2009 Mar;69(2):406-12
18938008
Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1944-8
10677559
Cereb Cortex. 2008 Dec;18(12):2811-9
18372290
Cereb Cortex. 2000 Jan;10(1):93-107
10639399
Psychiatry Res. 2008 Jan 15;162(1):27-37
18063349