Polymicrobial necrotizing fasciitis involving enterobacteria producing CTX-M-15 extended-spectrum β-lactamases.
Necrotizing fasciitis due to multiple Gram-negative organisms in a Nigerian patient is described. Morganella morganii and Citrobacter freundii carrying the CTX-M-15 extended-spectrum β-lactamase gene were isolated, highlighting the emergence of this β-lactamase in Western Africa and its successful spread amongst a wider range of members of the Enterobacteriaceae.
Soleimanian
S
S
Division of Infection, Barts & The London NHS Trust, London, UK.
Gordon
N C
NC
Division of Infection, Barts & The London NHS Trust, London, UK.
Wareham
D W
DW
Queen Mary University London, Centre for Immunology and Infection, Blizard Institute of Cell and Molecular Science, Barts & The London School of Medicine and Dentistry, London, UK.|Division of Infection, Barts & The London NHS Trust, London, UK.
D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics*; D016971:Citrobacter freundii / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D019115:Fasciitis, Necrotizing / Q000382:microbiology*; D006801:Humans; D008297:Male; D020613:Morganella morganii / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D009549:Nigeria; D001618:beta-Lactamases / Q000235:genetics*
D001426:Bacterial Proteins; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases