Neurological soft signs in individuals with schizotypal personality features.
OBJECTIVE
The current study attempted to examine the prevalence of neurological soft signs and their relationships with schizotypal traits in individuals with psychometrically defined schizotypal personality disorder (SPD) features.


METHODS
Sixty-four individuals with SPD-proneness and 51 without SPD-proneness were recruited for the present study. The soft signs subscales of the Cambridge Neurological Inventory were administered to all participants; the Schizotypal Personality Questionnaire (SPQ) was administered to SPD-proneness and non-SPD-proneness participants.


RESULTS
The SPD-proneness participants demonstrated significantly higher prevalence of soft signs than those without SPD-proneness. SPQ subscales were significantly associated with ratings of motor coordination, sensory integration and total soft signs.


CONCLUSIONS
These findings suggest that neurological soft signs are trait markers of schizophrenia.
Chan
Raymond C K
RC
Neuropsychology and Applied Cognitive Neuroscience Laboratory, and Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 4A Datun Road, Beijing, China. rckchan@psych.ac.cn
Wang
Ya
Y
Zhao
Qing
Q
Yan
Chao
C
Xu
Ting
T
Gong
Qi-Yong
QY
Manschreck
Theo C
TC
D000704:Analysis of Variance; D058068:Endophenotypes; D005260:Female; D006801:Humans; D008297:Male; D009460:Neurologic Examination; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D012569:Schizotypal Personality Disorder / Q000175:diagnosis*; D011795:Surveys and Questionnaires; D055815:Young Adult