title: Study on secondary metabolite content of Helleborus niger L. leaves.
abstract: Phytochemical investigation of Helleborus niger L. (Ranunculaceae) leaf methanol extract allowed to isolate a phenolic glucoside derivative and two flavonoid glycosides characterized as phenyllactic acid 2-O-β-D-glucopyranoside (1), quercetin 3-O-2-(E-caffeoyl)-α-L-arabinopyranosyl-(1 → 2)-β-D-glucopyranoside-7-O-β-D-glucopyranoside (2), and kaempferol 3-O-α-L-arabinopyranosyl-(1 → 2)-β-D-galactopyranoside-7-O-β-D-glucopyranoside (3), respectively. Compounds 1 and 2 were isolated for the first time and their structural characterization was obtained on the basis of extensive NMR spectral studies.
authors.affiliation: Dipartimento di Produzione Vegetale, Università degli Studi di Milano, via Celoria 2, 20133 Milano, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Vitalini
authors.forename: Alessandra
authors.initials: A
authors.lastname: Braca
authors.forename: Gelsomina
authors.initials: G
authors.lastname: Fico
mesh_terms: D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D039322:Helleborus / Q000737:chemistry*; D044949:Kaempferols / Q000737:chemistry* / Q000302:isolation & purification; D007773:Lactates / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D005960:Glucosides; D044949:Kaempferols; D007773:Lactates; D010936:Plant Extracts; C560457:kaempferol-3-O-alpha-L-arabinopyranosyl-(1-2)-beta-D-galactopyranoside-7-O-beta-D-glucopyranoside; C560456:phenyllactic acid 2-O-beta-D-glucopyranoside; C560458:quercetin-3-O-2-(E-caffeoyl)-alpha-L-arabinopyranosyl-(1-2)-beta-D-glucopyranoside-7-O-beta-D-glucopyranoside; D011794:Quercetin