[Transrectal high-intensity focused ultrasound for treatment of benign prostatic hyperplasia: report of 262 cases].
OBJECTIVE
To explore the application of transrectal high-intensity focused ultrasound (HIFU) for treatment of benign prostatic hyperplasia (BPH).


METHODS
From Dec. 2002 to Dec. 2006, 262 BPH patients underwent transrectal HIFU ablative therapy. After the treatment, IPSS, QOL score, peak uroflow rate and prostatic volume measured by TRUS were used for evaluation.


RESULTS
After 1 to 3 years' follow-up, IPSS, QOL score, and prostatic volume all decreased, while the peak uroflow rate increased obviously (P<0.01). Mild hematuria was noted in all the cases after the treatment, and epididymitis was found in 7 cases (2.7%), short-term hematospermia in 66 cases (25.2%), retrograde ejaculation in 35 cases (13.4%), and urethro-rectal fistula in 1 case (0.3%). No urinary incontinence was found in these cases. TURP was performed in 18 cases (6.8%) in 3 years after the treatment due to an excessively large volume of the prostates or bladder neck contracture.


CONCLUSIONS
HIFU is effective and safe in the treatment of BPH which causes minimal invasion, absence of intraoperative bleeding, good tolerance and few complications, and is especially suitable in elderly patients.
Xu
Wen-feng
WF
Department of Urology, Foshan First People's Hospital, Foshan 528000, China. foxwf@21cn.com
Zhang
Hai-bin
HB
Lin
Zhe
Z
Yang
Ming
M
Liu
Jian-hua
JH
Ye
Shan
S
Chen
Yong
Y
Yu
Yue-yi
YY
D000368:Aged; D000369:Aged, 80 and over; D057086:High-Intensity Focused Ultrasound Ablation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000628:therapy*; D016896:Treatment Outcome