Multi-site abdominal tuberculosis mimics malignancy on 18F-FDG PET/CT: report of three cases.
18F-fluorodeoxyglucose positron emission/computed tomography (18F-FDG PET/CT) imaging, an established procedure for evaluation of malignancy, shows an increased 18F-FDG uptake in inflammatory conditions. We present three patients with abdominal pain and weight loss. Conventional imaging studies indicated that abdominal neoplasm and 18F-FDG PET/CT for assessment of malignancy showed multiple lesions with intense 18F-FDG uptake in abdomen of the three cases. However, the three patients were finally diagnosed with multi-site abdominal tuberculosis (TB). Of them, two were diagnosed with TB by pathology, one was diagnosed with TB clinically. They recovered after anti-TB therapy. Few reports on accumulation of 18F-FDG in abdominal TB are available in the literature. A high index of suspicion is necessary to achieve an early diagnosis and a better outcome of the disease.
Tian
Geng
G
Department of Tumor, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, 3002 Sungang West Road, Shenzhen 518035, Guangdong Province, China. tiangeng666@yahoo.com.cn
Xiao
Yong
Y
Chen
Bin
B
Guan
Hong
H
Deng
Qun-Yi
QY
D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging*; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000000981:diagnostic imaging* / Q000188:drug therapy
D000995:Antitubercular Agents; D019788:Fluorodeoxyglucose F18
Chang Gung Med J. 2009 Sep-Oct;32(5):509-16
19840508
World J Gastroenterol. 2009 Sep 21;15(35):4434-8
19764096
World J Gastroenterol. 2008 Aug 7;14(29):4627-32
18698676
AJR Am J Roentgenol. 2010 Mar;194(3):555-61
20173128
J Nucl Med. 2002 Jul;43(7):871-5
12097455
Clin Nucl Med. 2007 Mar;32(3):244-6
17314612
J Nucl Med. 2001 Sep;42(9):1412-7
11535734
Pathologica. 2009 Dec;101(6):261-2
20387716
World J Gastroenterol. 2009 Apr 21;15(15):1836-42
19370780
Nucl Med Commun. 2009 Jun;30(6):455-61
19381115
World J Gastroenterol. 2009 Aug 7;15(29):3691-3
19653352
Clin Nucl Med. 2007 Sep;32(9):716-8
17710027
Pediatr Surg Int. 2010 Apr;26(4):413-8
20162421
Clin Nucl Med. 2009 Nov;34(11):815-7
19851185
J Cancer Res Clin Oncol. 2010 Dec;136(12):1839-44
20217130
J Comput Assist Tomogr. 2009 Jul-Aug;33(4):587-92
19638856
JOP. 2010 Jan 08;11(1):72-4
20065559