title: New fluorescent trans-dihydrofluoren-3-ones from aldol-Robinson annulation-regioselective addition involved one-pot reaction.
abstract: An unexpected discovery of new trans-4-acetyl-1,9-dimethyl-4,4a-dihydro-3H-fluoren-3-ones from one pot reactions of benzaldehydes and acetylacetone is described. The synthetic mechanism and stereochemistry were discussed. These new derivatives exhibit good fluorescent properties in solutions.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.
authors.forename: Yingpeng
authors.initials: Y
authors.lastname: Huo
authors.forename: Xu
authors.initials: X
authors.lastname: Qiu
authors.forename: Weiyan
authors.initials: W
authors.lastname: Shao
authors.forename: Jianing
authors.initials: J
authors.lastname: Huang
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Yu
authors.forename: Yinglin
authors.initials: Y
authors.lastname: Zuo
authors.forename: Linkun
authors.initials: L
authors.lastname: An
authors.forename: Jun
authors.initials: J
authors.lastname: Du
authors.forename: Xianzhang
authors.initials: X
authors.lastname: Bu
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D045744:Cell Line, Tumor; D002625:Chemistry, Organic / Q000379:methods*; D018360:Crystallography, X-Ray; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D006801:Humans; D018613:Microscopy, Confocal; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D005449:Fluorenes; D005456:Fluorescent Dyes; C116609:3-hydroxybutanal