Tolerance of benznidazole in treatment of Chagas' disease in adults.
Chagas' disease is an emerging public health problem in areas where the disease is not endemic. Treatment with benznidazole has shown efficacy in the acute stage of the disease, but its efficacy in the chronic stage remains controversial, and unwanted side effects are more frequent and severe in adults than in children. This study describes the profile of side effects of benznidazole in a cohort of Trypanosoma cruzi-infected patients in a European country.
Pinazo
María-Jesús
MJ
Tropical Diseases Section, Barcelona Centre for International Health Research, Hospital Clinic, Villarroel 170, Barcelona, Spain. mpinazo@clinic.ub.es
Muñoz
José
J
Posada
Elizabeth
E
López-Chejade
Paulo
P
Gállego
Montserrat
M
Ayala
Edgar
E
del Cacho
Elena
E
Soy
Dolors
D
Gascon
Joaquim
J
D000293:Adolescent; D000328:Adult; D014355:Chagas Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009593:Nitroimidazoles / Q000009:adverse effects* / Q000627:therapeutic use*; D014344:Trypanocidal Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D055815:Young Adult
D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole
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