Detection, evaluation, and management of iron-restricted erythropoiesis.
Progress in our understanding of iron-restricted erythropoiesis has been made possible by important advances in defining the molecular mechanisms of iron homeostasis. The detection and diagnostic classification of iron-restricted erythropoiesis can be a challenging process for the clinician. Newer assays for markers of inflammation may allow more targeted management of the anemia in these conditions. The availability of new intravenous iron preparations provides new options for the treatment of iron-restricted erythropoiesis. This review summarizes recent advances regarding the detection, evaluation, and management of iron-restricted erythropoiesis.
Goodnough
Lawrence Tim
LT
Departments of Pathology and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. ltgoodnough@stanfordmed.org
Nemeth
Elizabeta
E
Ganz
Tomas
T
D018798:Anemia, Iron-Deficiency / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy*; D004920:Erythropoiesis; D006801:Humans; D000090463:Iron Deficiencies; D019266:Iron, Dietary / Q000378:metabolism
D019266:Iron, Dietary