title: [Effects of bioactive molecules of Beta vulgaris L. ssp. esculenta var. rubra on metastatic prostate cancer].
abstract: Several reports are known about the effects of nutrition supplements in the improvement of quality of life of patients with tumor, however, the physiological background remains largely unknown. Table beet affects numerous biochemical reactions, enzymes and metabolic-synthesis.
  
  
  METHODS
  Natural table beet product come from commercial service was given twice 10 g daily for 1 month for 24 patients (mean age 68+/-8 years) with hormone-resistant and metastatic prostate cancer treated with taxan chemotherapy, who report themselves first, mean 3,6+/-2,8 years ago with their complains. 18 men's data were amenable after treatment for evaluation. In addition to routine laboratory examination values of HbA1c, 9 cytokines and levels of 3 growth factors, the global parameters of redox-homeostasis, few elements of their metal-ions, Zn- and level of free protoporfirin, trans-metilating processes before and 1 month after treatment were determined.
  
  
  RESULTS
  In most of the patients, favorable impact of beet was enforced and significantly high levels of Zn- and free protoporfirin decreased; furthermore, trans-metilating processes fastened.
  
  
  CONCLUSIONS
  According to results, it seems that moderate and permanent consumption of table beet product affects the life expectancy of patients favorably; however, due to the increasing values of EGF, medical control is necessary for patients with prostate cancer treated by chemotherapy.
authors.affiliation: Semmelweis Egyetem, Altalános Orvostudományi Kar Urológiai, Klinika és Uroonkológiai Centrum Budapest. nyiradyp@homail.com
authors.forename: Péter
authors.initials: P
authors.lastname: Nyirády
authors.forename: Eva
authors.initials: E
authors.lastname: Sárdi
authors.forename: Gabriella
authors.initials: G
authors.lastname: Beko
authors.forename: Miklós
authors.initials: M
authors.lastname: Szucs
authors.forename: András
authors.initials: A
authors.lastname: Horváth
authors.forename: Edit
authors.initials: E
authors.lastname: Székely
authors.forename: Klára
authors.initials: K
authors.lastname: Szentmihályi
authors.forename: Imre
authors.initials: I
authors.lastname: Romics
authors.forename: Anna
authors.initials: A
authors.lastname: Blázovics
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000188:drug therapy* / Q000556:secondary; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D027461:Beta vulgaris / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D000077143:Docetaxel; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods; D010936:Plant Extracts / Q000627:therapeutic use; D011471:Prostatic Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D043823:Taxoids / Q000627:therapeutic use; D014131:Trace Elements / Q000097:blood; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D010936:Plant Extracts; D043823:Taxoids; D014131:Trace Elements; D000077143:Docetaxel