title: A newly designed big cup nitinol stent for gastric outlet obstruction.
abstract: OBJECTIVE
  To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer.
  
  
  METHODS
  The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in diameter) covered by a polyethylene membrane and a distal sphericity (20 mm in length and 28 mm in diameter). Half of the proximal big cup segment is also covered by a polyethylene membrane, which is adjacent to the middle part of the stent. The stent is preloaded in a 6.0-mm-diameter introducer system. Thirteen patients with gastric outlet obstruction resulting from gastric cancer received the new stents under endoscopic and fluoroscopic guidance.
  
  
  RESULTS
  Technical success was achieved in 12 of 13 (92.3%) patients. Among the 12 patients in whom endoscopic stent was placed successfully, the clinical success rate was 91.7% during a follow-up of average 6.5 mo. During the first month follow-up, the migration rate was 0%, recurrent obstruction 0% and gastric bleeding 8.3%. During the follow-up between 2-12 mo, no migration, recurrent obstruction and gastric bleeding occurred.
  
  
  CONCLUSIONS
  The proximal big cup segment seems to be effective and promising for technical efficacy, clinical outcome, and preventing migration and tumor ingrowth and increasing the emptying rate of sinus ventriculi.
authors.affiliation: Institute for Biomedical Engineering, Nanjing University of Technology, PO Box 128, 5 Xinmofan Road, Nanjing 210009, Jiangsu Province, China.
authors.forename: Ding
authors.initials: D
authors.lastname: Shi
authors.forename: Sheng-Hui
authors.initials: SH
authors.lastname: Liao
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Geng
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005548:Foreign-Body Migration / Q000517:prevention & control; D017219:Gastric Outlet Obstruction / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness / Q000517:prevention & control; D020959:Polyethylene; D015995:Prevalence; D015607:Stents; D013274:Stomach Neoplasms / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000497:Alloys; C013616:nitinol; D020959:Polyethylene
references.citation: Dig Dis Sci. 2010 Mar;55(3):668-74
references.pmid: 19333756
references.citation: Gastrointest Endosc. 2001 Sep;54(3):364-7
references.pmid: 11522983
references.citation: Gastrointest Endosc. 2007 Aug;66(2):256-64
references.pmid: 17643698
references.citation: Clin Radiol. 2007 Aug;62(8):738-44
references.pmid: 17604761
references.citation: AJR Am J Roentgenol. 2009 Jul;193(1):241-7
references.pmid: 19542420
references.citation: Eur J Radiol. 2002 Jun;42(3):240-8
references.pmid: 12044702
references.citation: Am J Gastroenterol. 2002 Jan;97(1):72-8
references.pmid: 11808972
references.citation: J Clin Gastroenterol. 2005 Feb;39(2):124-8
references.pmid: 15681907
references.citation: Gastrointest Endosc. 1998 Mar;47(3):267-70
references.pmid: 9540881
references.citation: Gastrointest Endosc. 2004 Dec;60(6):916-20
references.pmid: 15605006
references.citation: Gastrointest Endosc. 2007 Dec;66(6):1206-10
references.pmid: 18028923
references.citation: Clin Radiol. 2001 Jul;56(7):560-7
references.pmid: 11446754
references.citation: Scand J Gastroenterol. 2009;44(7):846-52
references.pmid: 19462336
references.citation: Clin Radiol. 2002 Jul;57(7):587-92
references.pmid: 12096856
references.citation: Gastrointest Endosc. 1998 Mar;47(3):271-6
references.pmid: 9540882