Post-stroke depression: prevalence and relationship with disability in chronic stroke survivors.
OBJECTIVE
To evaluate (1) the prevalence of operationally defined depressive disorder (ICD-10) in chronic stroke subjects and (2) the relationship of post-stroke depression (PSD) with disability.


METHODS
Cross-sectional, descriptive study.


METHODS
Neurological rehabilitation unit of a tertiary care university research center.


METHODS
Participants were those with first episode of supratentorial stroke of more than 3 months' duration with impaired balance and gait who had been referred for rehabilitation. Data were collected on demographic data, stroke data (side and type of lesion and post-stroke duration), cognition (mini mental state examination), depressive ideation (Hamilton Depression Rating Scale - HRDS), impairment (Scandinavian Stroke Scale), balance (Berg Balance Scale), ambulatory status (Functional Ambulation Category), walking ability (speed), and independence in activities of daily living (Barthel Index). Statistical analysis was done using SPSS 13.0. We carried out the chi-square test for ordinal variables and the independent t test for continuous variables.


RESULTS
Fifty-one patients (M:F: 41:10) of mean age 46.06 +/- 11.19 years and mean post-stroke duration of 467.33 +/- 436.39 days) were included in the study. Eighteen of the 51 participants (35.29%) met the criteria for depression. Demographic variables like male gender, being married, living in a nuclear family, urban background, and higher HRDS score were significantly correlated with PSD (P < 0.05). Depression was related to functional disability after stroke but to a statistically insignificant level (P > 0.05) and was unrelated to lesion-related parameters.


CONCLUSIONS
Depression occurs in one-third of chronic stroke survivors and is prevalent in subjects referred for rehabilitation. PSD is related primarily to demographic variables and only to a lesser extent to functional disability following stroke.
Srivastava
Abhishek
A
Center for Physical Medicine & Rehabilitation, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Bangalore-560029, India. abhishek.m.srivastava@relianceada.com
Taly
Arun B
AB
Gupta
Anupam
A
Murali
Thyloth
T
J Psychiatr Res. 1975 Nov;12(3):189-98
1202204
Neurology. 1997 Nov;49(5 Suppl 4):S39-44
9371148
Stroke. 1983 Sep-Oct;14(5):736-41
6658957
Neuropsychiatr Dis Treat. 2008 Feb;4(1):145-54
18728805
Stroke. 2001 Jan;32(1):113-7
11136924
Bangladesh Med Res Counc Bull. 2001 Dec;27(3):96-102
12197629
Lancet. 2000 Jul 8;356(9224):122-6
10963248
Stroke. 1985 Sep-Oct;16(5):885-90
3901425
Qual Life Res. 1999 Jun;8(4):293-301
10472161
Arch Phys Med Rehabil. 1992 Nov;73(11):1073-80
1444775
Stroke. 1995 Nov;26(11):2011-5
7482640
Stroke. 1994 Jul;25(7):1360-5
8023350
Stroke. 2000 Dec;31(12):2995-3000
11108762
Md State Med J. 1965 Feb;14:61-5
14258950
Stroke. 1987 May-Jun;18(3):579-84
3590249
Neurol Neurochir Pol. 2003 Jan-Feb;37(1):17-25
12910825
J Neurol Neurosurg Psychiatry. 1960 Feb;23:56-62
14399272
Arch Phys Med Rehabil. 1999 Sep;80(9):985-90
10488996
J Neurol. 2006 May;253(5):556-62
16767539
Arch Phys Med Rehabil. 2001 Dec;82(12):1645-9
11733876
Disabil Rehabil. 2004 Jan 21;26(2):71-7
14668142
Singapore Med J. 2006 Mar;47(3):213-8
16518556
Stroke. 1995 Jun;26(6):982-9
7762050
Stroke. 2005 Jun;36(6):1330-40
15879342
Scand J Rehabil Med. 1987;19(1):25-30
3576138
Stroke. 2000 Jul;31(7):1588-601
10884459
Psychosomatics. 1992 Summer;33(3):290-4
1410202
Nurs Times. 1991 Apr 10-16;87(15):53-4
2020581