title: Luteal phase estradiol versus luteal phase estradiol and antagonist protocol for controlled ovarian stimulation before in vitro fertilization in poor responders.
abstract: Luteal phase synchronization of follicular growth has been suggested as a means to improve ovarian response in low responders. We compared luteal E2 and antagonist (n=256) with luteal E2 only (n=57) before antagonist protocol in low responders. The addition of GnRH antagonist to luteal E2 for luteal suppression before ovarian stimulation for IVF does not improve IVF outcomes in poor responders.
authors.affiliation: Center for Advanced Reproductive Services, University of Connecticut Health Center, Farmington, Connecticut 06030-6224, USA.
authors.forename: Alyaa
authors.initials: A
authors.lastname: Elassar
authors.forename: Jessica Salas
authors.initials: JS
authors.lastname: Mann
authors.forename: Lawrence
authors.initials: L
authors.lastname: Engmann
authors.forename: John
authors.initials: J
authors.lastname: Nulsen
authors.forename: Claudio
authors.initials: C
authors.lastname: Benadiva
mesh_terms: D000328:Adult; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004958:Estradiol / Q000097:blood*; D004965:Estrogen Antagonists / Q000008:administration & dosage*; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008183:Luteal Phase / Q000502:physiology*; D006080:Ovarian Follicle / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: D004965:Estrogen Antagonists; D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D005640:Follicle Stimulating Hormone