Blockade of Janus kinase 2 signaling ameliorates mouse liver damage due to ischemia and reperfusion.
Bhogal
Ricky H
RH
Afford
Simon C
SC
D000818:Animals; D045744:Cell Line, Tumor; D004195:Disease Models, Animal; D022781:Hepatocytes / Q000187:drug effects* / Q000201:enzymology / Q000276:immunology; D053614:Janus Kinase 2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D008107:Liver Diseases / Q000201:enzymology / Q000276:immunology / Q000517:prevention & control*; D051379:Mice; D008810:Mice, Inbred C57BL; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D015427:Reperfusion Injury / Q000201:enzymology / Q000276:immunology / Q000517:prevention & control*; D015398:Signal Transduction / Q000187:drug effects*; D020032:Tyrphostins / Q000494:pharmacology*
D047428:Protein Kinase Inhibitors; D020032:Tyrphostins; C095512:alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide; C507926:Jak2 protein, mouse; D053614:Janus Kinase 2