Cataract and cognitive impairment: a review of the literature.
Acquired cataract and cognitive impairment are both common age-related problems, and ophthalmologists are increasingly likely to encounter patients who have both. Patients with dementia types who display early visuoperceptual impairment may present first to ophthalmology services. When these patients have coexisting cataract, it may be difficult to distinguish visual complaints due to cataract from those due to dementia. The interaction between visual impairment due to cataract and neurodegenerative disorders affecting the central visual pathways, is not fully understood. Visual impairment due to cataract may stress impaired attentional mechanisms and cataract extraction may improve cognitive performance in some patients with early cognitive impairment; however, the benefits of cataract surgery in established dementia are less clear. In this study, the literature on this subject was reviewed and the implications for practice were considered.
Jefferis
J M
JM
Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, UK. j.m.jefferis@ncl.ac.uk
Mosimann
U P
UP
Clarke
M P
MP
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications* / Q000175:diagnosis; D002387:Cataract Extraction; D003072:Cognition Disorders / Q000150:complications* / Q000175:diagnosis; D003704:Dementia / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D019636:Neurodegenerative Diseases / Q000150:complications; D016896:Treatment Outcome; D014786:Vision Disorders / Q000150:complications / Q000175:diagnosis; D014792:Visual Acuity
Br J Ophthalmol. 2009 Dec;93(12):1557-9
19286688
Arch Neurol. 1999 Mar;56(3):303-8
10190820
Lancet. 1996 Mar 9;347(9002):696-7
8596418
Surv Ophthalmol. 2006 Nov-Dec;51(6):592-5
17134649
J Clin Exp Neuropsychol. 1994 Apr;16(2):223-31
8021309
Eye (Lond). 2003 Apr;17(3):289-304
12724689
Ophthalmology. 2004 Feb;111(2):376-80; discussion 380-1
15019393
Brain. 2006 Mar;129(Pt 3):729-35
16401618
Eye (Lond). 2009 Jan;23(1):38-49
18034196
J Cataract Refract Surg. 2004 Mar;30(3):598-602
15050255
Arch Ophthalmol. 2007 Mar;125(3):401-2
17353414
Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2940-6
17525231
BMC Ophthalmol. 2006 Apr 20;6:17
16623958
J Clin Exp Neuropsychol. 2005 May;27(4):425-35
15962689
Acta Ophthalmol. 2008 Jun;86(4):401-3
18498549
J Am Geriatr Soc. 2005 Dec;53(12):2140-4
16398899
Int J Geriatr Psychiatry. 2000 Mar;15(3):219-25
10713579
Arch Ophthalmol. 2004 Apr;122(4):487-94
15078665
Arch Ophthalmol. 2009 May;127(5):667-73
19433718
Lancet. 2003 Apr 12;361(9365):1258-65
12699953
Optom Vis Sci. 1996 Nov;73(11):677-82
8950748
J Intern Med. 2004 Sep;256(3):183-94
15324362
Dialogues Clin Neurosci. 2009;11(2):111-28
19585947
Br J Ophthalmol. 1987 Feb;71(2):112-5
3828263
Neurology. 1990 Mar;40(3 Pt 1):439-43
2314585
Arch Ophthalmol. 2007 Jul;125(7):925-30
17620572
Br J Ophthalmol. 2005 Oct;89(10):1341-2
16170128
Arch Ophthalmol. 1991 Feb;109(2):244-51
1993036
Br J Ophthalmol. 1999 May;83(5):519-23
10216047
Science. 1994 Nov 11;266(5187):1051-4
7973660
Ophthalmology. 2000 Dec;107(12):2203-8
11097596
Neurosci Lett. 1991 Jan 14;122(1):53-6
1711658
Br J Ophthalmol. 2000 Dec;84(12):1380-2
11090477
Am J Ophthalmol. 2007 Apr;143(4):687-9
17386279
Am J Geriatr Psychiatry. 1995 Summer;3(3):198-205
28531041
Br J Psychiatry. 1997 Feb;170:156-8
9093505
Brain. 2004 Feb;127(Pt 2):431-8
14691059
J Neurol Sci. 2006 Jul 15;246(1-2):79-83
16564058
J Cataract Refract Surg. 2004 Dec;30(12):2459-60; author reply 2460
15617893
Lancet. 1995 Oct 7;346(8980):931-4
7564727
Am J Geriatr Pharmacother. 2008 Jun;6(2):100-18
18675769
Lancet Neurol. 2005 Oct;4(10):605-10
16168928
Br J Ophthalmol. 2004 May;88(5):716-8
15090431
Am J Geriatr Psychiatry. 1998 Spring;6(2 Suppl 1):S3-18
9581216
Am J Epidemiol. 2007 Aug 15;166(4):367-78
17573335
Rev Neurol (Paris). 2009 Mar;165(3):256-62
19124140
Arch Ophthalmol. 2006 Sep;124(9):1308-14
16966626
Acta Ophthalmol (Copenh). 1983 Jun;61(3):392-6
6624405
Int J Epidemiol. 1991 Sep;20(3):736-48
1955260
Eye (Lond). 2004 Aug;18(8):763-4
15295622
Eye (Lond). 2002 May;16(3):275-80
12032717
J Am Geriatr Soc. 2009 Feb;57(2):202-8
19170783
Ophthalmic Epidemiol. 2008 Sep-Oct;15(5):317-27
18850468
Am J Psychiatry. 1999 Dec;156(12):1983-5
10588415
Neurology. 1995 Jan;45(1):68-74
7824139
Neurology. 2004 Dec 14;63(11):2091-6
15596755
N Engl J Med. 1995 May 4;332(18):1205-9
7700315
Neurology. 2005 Dec 27;65(12):1863-72
16237129
Am J Clin Nutr. 2000 Dec;72(6):1495-502
11101477
Neurology. 2002 Dec 10;59(11):1714-20
12473758
Brain. 2008 May;131(Pt 5):1268-81
18362099
Arch Neurol. 2003 Mar;60(3):387-92
12633150
Am J Epidemiol. 1977 Jul;106(1):33-41
141882
Ann Epidemiol. 2001 Feb;11(2):104-10
11164126
J Fr Ophtalmol. 1999 May;22(4):431-7
10365330
Neurology. 1996 Nov;47(5):1113-24
8909416
J Cataract Refract Surg. 2006 Jan;32(1):60-6
16516780
Neuropsychiatr. 2008;22(1):1-15
18381051
Psychol Aging. 2003 Dec;18(4):714-26
14692859
J Neuropsychiatry Clin Neurosci. 1999 Fall;11(4):498-503
10570764
Brain. 2005 Jun;128(Pt 6):1267-76
15774501
Am J Ophthalmol. 1987 Aug 15;104(2):113-20
3618708
Surv Ophthalmol. 1980 May-Jun;24(Suppl):335-610
7444756
Psychol Aging. 1994 Sep;9(3):339-55
7999320
Int J Psychophysiol. 2009 Aug;73(2):143-9
19414041
Psychol Aging. 2001 Jun;16(2):196-205
11405308
Epidemiology. 2003 Jul;14(4):493-7
12843777
Surv Ophthalmol. 1995 Jan-Feb;39(4):323-34
7725232
J Neurol Sci. 1970 Sep;11(3):205-42
5505685
Lancet. 2005 Dec 17;366(9503):2112-7
16360788
Ophthalmology. 2001 Aug;108(8):1400-8
11470690
Eur Neurol. 2002;47(3):165-8
11914555
Neurocase. 2004 Oct;10(5):382-5
15788276
J Neurol Neurosurg Psychiatry. 1997 Mar;62(3):243-52
9069479
J Int Neuropsychol Soc. 2006 Sep;12(5):632-9
16961944
Am J Ophthalmol. 1985 Jul 15;100(1):68-72
3893141
Arch Neurol. 2000 Apr;57(4):489-93
10768622
J Am Geriatr Soc. 1991 Aug;39(8):755-9
2071805
Ophthalmology. 1997 Apr;104(4):581-8
9111249
Insight. 1996 Apr;21(1):9-12
8826225
Semin Neonatol. 2001 Dec;6(6):477-85
12014888
Am J Ophthalmol. 2008 Sep;146(3):404-9
18602079
Curr Opin Ophthalmol. 1994 Dec;5(6):38-44
10172410
Ophthalmology. 1989 Jul;96(7):1077-85; discussion 1085-6
2788851
Curr Opin Ophthalmol. 1998 Feb;9(1):10-3
10178625
Int J Geriatr Psychiatry. 1997 Aug;12(8):785-90
9283922