title: The long and short of fertility and longevity.
abstract: Does life span extension come with a reproductive trade-off? In a recent report published in Nature, Greer et al. (2010) show that in the nematode worm C. elegans, life span extension, as a consequence of deficiencies in histone methylation, requires an intact germline and ongoing fertility.
authors.affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute for Aging Research, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute of Aging Research, Guangdong Medical College, Dongguan 523808, China.
authors.forename: Yousin
authors.initials: Y
authors.lastname: Suh
authors.forename: Jan
authors.initials: J
authors.lastname: Vijg
references.citation: Nature. 2010 Mar 25;464(7288):504-12
references.pmid: 20336132
references.citation: Nature. 2010 Jul 15;466(7304):383-7
references.pmid: 20555324
references.citation: Nature. 1999 May 27;399(6734):362-6
references.pmid: 10360574
references.citation: Proc Biol Sci. 2004 Dec 7;271(1556):2523-6
references.pmid: 15590605
references.citation: Science. 2010 Apr 16;328(5976):321-6
references.pmid: 20395504
references.citation: Science. 2002 Jan 18;295(5554):502-5
references.pmid: 11799246
references.citation: Nature. 1998 Dec 24-31;396(6713):743-6
references.pmid: 9874369
references.citation: Genes Dev. 2008 May 1;22(9):1115-40
references.pmid: 18451103