[Successful symptomatic treatment of epidermodysplasia verruciformis with imiquimod 5% cream].
A 19-year-old patient presented with epidermodysplasia verruciformis (EV). In this genodermatosis, pathogenetic factors such as infection by human papilloma viruses as well as sun exposure are considered responsible for the malignant transformation of EV lesions to skin cancer within decades. So far, several therapeutic strategies have been unsatisfactory. In our case HPV 5b was detected and the associated skin lesions were successfully treated with imiquimod 5% cream.
Heratizadeh
A
A
Klinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover, Ricklinger Str. 5, 30449, Hannover. Heratizadeh.Annice@MH-Hannover.de
Völker
B
B
Kupsch
E
E
Wichmann
K
K
Kapp
A
A
Werfel
T
T
D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000009:adverse effects; D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage* / Q000009:adverse effects; D001706:Biopsy; D003241:Consanguinity; D015344:DNA Probes, HPV; D004334:Drug Administration Schedule; D003875:Drug Eruptions / Q000209:etiology; D004819:Epidermodysplasia Verruciformis / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D008297:Male; D020411:Oligonucleotide Array Sequence Analysis; D030361:Papillomavirus Infections / Q000150:complications / Q000175:diagnosis; D012867:Skin / Q000473:pathology
D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D015344:DNA Probes, HPV; D000077271:Imiquimod
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