Outcome of surgical treatment of intestinal perforation in typhoid fever.
OBJECTIVE
To represent our clinical experience in the treatment of intestinal perforation arising from typhoid fever.


METHODS
The records of 22 surgically-treated patients with typhoid intestinal perforation were evaluated retrospectively.


RESULTS
There were 18 males and 4 females, mean age 37 years (range, 8-64 years). Presenting symptoms were fever, abdominal pain, diarrhea or constipation. Sixteen cases were subjected to segmental resection and end-to-end anastomosis, while 3 cases received 2-layered primary repair following debridement, one case with multiple perforations received 2-layered primary repair and end ileostomy, one case received segmental resection and end-to-end anastomosis followed by an end ileostomy, and one case received segmental resection and end ileostomy with mucous fistula operation. Postoperative morbidity was seen in 5 cases and mortality was found in one case.


CONCLUSIONS
Intestinal perforation resulting from Salmonella typhi is an important health problem in Eastern and Southeastern Turkey. In management of this illness, early and appropriate surgical intervention is vital.
Sümer
Aziz
A
Department of General Surgery, Medical Faculty, University of Yüzüncü Yil, Van 6500, Turkey. azizsumer2002@yahoo.com
Kemik
Ozgür
O
Dülger
Ahmet Cumhur
AC
Olmez
Aydemir
A
Hasirci
Ismail
I
Kişli
Erol
E
Bayrak
Vedat
V
Bulut
Gulay
G
Kotan
Cetin
C
D000293:Adolescent; D000328:Adult; D002648:Child; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000379:methods; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014421:Turkey; D014435:Typhoid Fever / Q000150:complications*; D055815:Young Adult
Rev Infect Dis. 1985 Mar-Apr;7(2):244-56
3890097
Am J Epidemiol. 2004 Jul 1;160(1):46-50
15229116
JSLS. 2005 Oct-Dec;9(4):399-402
16381353
Ann Surg. 1979 Jul;190(1):31-5
464674
Hong Kong Med J. 2007 Dec;13(6):475-7
18057437
World J Surg. 1998 Mar;22(3):319-23
9494426
Surgery. 1998 Jun;123(6):632-6
9626313
World J Surg. 2007 Sep;31(9):1883-1888
17629741
Pediatr Surg Int. 2002 Dec;18(8):696-700
12598967
J Postgrad Med. 2001 Oct-Dec;47(4):248-51
11832640
J R Coll Surg Edinb. 1997 Dec;42(6):395-9
9448395
Pediatr Surg Int. 2001 Nov;17(8):628-30
11727054
West Afr J Med. 2003 Jan-Mar;22(1):22-5
12769301
Dig Dis Sci. 2004 Jan;49(1):161-4
14992453
Am J Surg. 2005 Mar;189(3):342-4
15792765
Ann Surg. 1992 Mar;215(3):244-9
1543396
Langenbecks Arch Surg. 2008 Nov;393(6):973-7
18026981
Ann Trop Paediatr. 1999 Sep;19(3):267-72
10715713
Int Surg. 1999 Jan-Mar;84(1):35-8
10421015
Ethiop Med J. 2000 Oct;38(4):227-35
11125497
Surg Laparosc Endosc Percutan Tech. 2004 Jun;14(3):122-4
15471016
East Afr Med J. 1997 Dec;74(12):796-9
9557425
Ann Trop Paediatr. 2008 Mar;28(1):53-8
18318950
Arch Surg. 1983 Nov;118(11):1269-71
6639337