title: [A case of advanced adenocarcinoma of the lung which maintained complete response for 5 years by treatment with gefitinib].
abstract: A 73-year-old woman smoker presented with dyspnea on exertion due to massive left pleural effusion. A CT scan after drainage of the pleural effusion demonstrated a nodule in the left lung, and cytology of the pleural effusion showed adenocarcinoma. We diagnosed advanced adenocarcinoma of the lung, and clinical stage IIIB. Chemotherapy with carboplatin and docetaxel was discontinued after the second course because of anorexia, and gefitinib was administered from October 2004. The lung nodule and pleural effusion had disappeared on CT by November 2004. A complete response continued for 5 years. We report a 5-year complete response in a case of advanced adenocarcinoma of the lung by treatment with gefitinib.
authors.affiliation: Department of Internal Medicine, Tokyo Dental College.
authors.forename: Tatsu
authors.initials: T
authors.lastname: Matsuzaki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Terashima
authors.forename: Rika
authors.initials: R
authors.lastname: Ogawa
authors.forename: Asuka
authors.initials: A
authors.lastname: Naitou
authors.forename: Jun
authors.initials: J
authors.lastname: Miyauchi
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Morishita
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D000077156:Gefitinib; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D011799:Quinazolines / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D011799:Quinazolines; D000077156:Gefitinib