Pregnancy-associated parvovirus B19 infection causing postinfectious glomerulonephritis.
BACKGROUND
Postinfectious glomerulonephritis due to parvovirus B19 during pregnancy is not described in the literature.


OBJECTIVE
A case and renal biopsy of postinfectious glomerulonephritis due to parvovirus B19 during pregnancy is presented.


CONCLUSIONS
The patient contracted "fifth disease," parvovirus B19, in the 10th week of pregnancy, and 2 weeks later developed hypertension, nephrotic range proteinuria, pleural effusions, and evidence of pure red cell aplasia. Serum parvovirus B19 IgM was positive; a renal biopsy was performed, revealing diffuse proliferative glomerulonephritis with immunofluorescent and electron microscopic changes consistent with postinfectious glomerulonephritis. Renal, hemodynamical, and hematological parameters returned to normal by the 16th week gestation, and the pregnancy proceeded without further complication to the mother, with term delivery of a healthy infant.
Podymow
Tiina
T
Division of Nephrology, McGill University Health Center, Royal Victoria Hospital, Montreal, Quebec, Canada. tiina.podymow@muhc.mcgill.ca
Muhtadie
Lina
L
D000328:Adult; D016731:Erythema Infectiosum / Q000150:complications* / Q000821:virology; D005260:Female; D005921:Glomerulonephritis / Q000821:virology*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*