title: Frequent prosthesis refitting to prevent implant exposure in patients with retinoblastoma.
abstract: OBJECTIVE
  To examine the effects of prosthesis refitting on porous orbital implant exposure in 100 patients who underwent enucleation for retinoblastoma.
  
  
  METHODS
  Parameters analyzed included patient's age at enucleation, gender, implant type, frequency of prosthesis adjustment, and use of chemotherapy or radiation. The main outcome measures consisted of the condition of the fornices, condition of the implant (including conjunctival thinning), and condition and functioning ability of the prosthesis.
  
  
  RESULTS
  Increased frequency of visits with the ocularist and number of prosthesis adjustments and refits significantly improved the condition of the implant, fornices, and prosthesis. The patient's age at enucleation, gender, and use of chemotherapy or radiation did not have a significant effect on any of the outcome variables. The condition of the implant was significantly better for porous polyethylene than hydroxyapatite implants (P = .024). No implant exposures were observed.
  
  
  CONCLUSIONS
  Frequent adjustments and refits by the ocularist are significantly associated with a reduced rate of conjunctival thinning and complete avoidance of implant exposure in patients undergoing enucleation for retinoblastoma. These findings are particularly significant for this population, which historically has demonstrated a high rate of implant exposure.
authors.affiliation: Rosalind Franklin University of Medicine and Science BKW, North Chicago, Illinois, USA.
authors.forename: Basil K
authors.initials: BK
authors.lastname: Williams
authors.forename: Amy C
authors.initials: AC
authors.lastname: Schefler
authors.forename: Scott N
authors.initials: SN
authors.lastname: Garonzik
authors.forename: Daniel
authors.initials: D
authors.lastname: Gologorsky
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Ludimila L
authors.initials: LL
authors.lastname: Cavalcante
authors.forename: Milena L
authors.initials: ML
authors.lastname: Cavalcante
authors.forename: William J
authors.initials: WJ
authors.lastname: Feuer
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Murray
mesh_terms: D015353:Eye Enucleation; D006801:Humans; D020273:Orbital Implants; D020959:Polyethylene; D019919:Prosthesis Implantation; D012175:Retinoblastoma / Q000188:drug therapy
chemical_list: D020959:Polyethylene