Multicenter evaluation of the BD Max GBS assay for detection of group B streptococci in prenatal vaginal and rectal screening swab specimens from pregnant women.
A new integrated extraction and real-time PCR-based system for the detection of group B streptococci in antepartum screening samples enriched in Lim broth was compared to the CDC-recommended culture method. The BD Max GBS assay exhibited acceptable sensitivity (95%) and specificity (96.7%) compared to those of the culture method in this multisite evaluation.
Riedlinger
Jennifer
J
BD-HandyLab, Ann Arbor, Michigan, USA.
Beqaj
Safedin H
SH
Milish
Marsha A
MA
Young
Stephen
S
Smith
Rebecca
R
Dodd
Monique
M
Hankerd
Rosemary E
RE
Lebar
William D
WD
Newton
Duane W
DW
D001431:Bacteriological Techniques / Q000379:methods*; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D016133:Polymerase Chain Reaction / Q000379:methods; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology; D011295:Prenatal Care / Q000379:methods; D011933:Reagent Kits, Diagnostic; D012007:Rectum / Q000382:microbiology; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology
D011933:Reagent Kits, Diagnostic
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