Preparation of a stationary phase with s-triazine ring embedded group for reversed phase high-performance LC.
This paper describes the synthesis and chromatographic evaluation of a new polar-embedded stationary phase, which utilized 2,4,6-trichloro-1,3,5-triazine as the spacer. The resulting materials were characterized by elemental analysis, IR, and solid-state (13)C NMR. Empirical test mixtures were utilized to evaluate the column, and showed that it had good performance for basic compounds and high selectivity for polyaromatic hydrocarbons. Moreover, the novel stationary phase has unique property, especially in the separation of "homologous alkaloids" from natural products.
Li
Yingyu
Y
Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, Shanghai, PR China.
Dai
Peichun
P
Ke
Yanxiong
Y
Jin
Yu
Y
Liang
Xinmiao
X
D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D015394:Molecular Structure; D014227:Triazines / Q000737:chemistry*
D014227:Triazines