Guaroa virus infection among humans in Bolivia and Peru.
Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.
Aguilar
Patricia V
PV
Naval Medical Research Center Detachment, Lima, Peru. patricia.aguilar@med.navy.mil
Morrison
Amy C
AC
Rocha
Claudio
C
Watts
Douglas M
DM
Beingolea
Luis
L
Suarez
Victor
V
Vargas
Jorge
J
Cruz
Cristhopher
C
Guevara
Carolina
C
Montgomery
Joel M
JM
Tesh
Robert B
RB
Kochel
Tadeusz J
TJ
D001838:Bolivia / Q000453:epidemiology; D006801:Humans; D016851:Orthobunyavirus / Q000502:physiology*; D010568:Peru / Q000453:epidemiology
Am J Trop Med Hyg. 1997 Jun;56(6):661-7
9230800
Am J Trop Med Hyg. 1967 Nov;16(6):778-81
6066225
PLoS Negl Trop Dis. 2008;2(12):e349
19079600
Am J Trop Med Hyg. 1962 Sep;11:691-6
14000396
J Virol. 1978 Oct;28(1):417-9
702656
Am J Trop Med Hyg. 2007 Feb;76(2):293-8
17297038
J Med Entomol. 2005 Sep;42(5):891-8
16366001
Vector Borne Zoonotic Dis. 2009 Dec;9(6):623-30
19196130
J Med Entomol. 2005 May;42(3):404-8
15962794
Am J Trop Med Hyg. 2001 Jan-Feb;64(1-2):93-7
11425170
J Gen Virol. 2009 Sep;90(Pt 9):2183-90
19439555
Am J Trop Med Hyg. 1966 May;15(3):369-78
4380042
Am J Trop Med Hyg. 1998 Jan;58(1):41-6
9452290
J Gen Virol. 1994 Mar;75 ( Pt 3):597-608
8126455
Am J Trop Med Hyg. 1998 Jan;58(1):35-40
9452289
Emerg Infect Dis. 2004 May;10(5):880-8
15200823
Cad Saude Publica. 2001;17 Suppl:155-64
11426277
Am J Trop Med Hyg. 1961 Mar;10:227-49
13691675
Curr Protoc Bioinformatics. 2003 Feb;Chapter 6:Unit 6.4
18428704
Am J Trop Med Hyg. 1959 Sep;8:604-9
13851794
Virology. 2001 Dec 20;291(2):185-90
11878887
Am J Trop Med Hyg. 2007 Mar;76(3):408-16
17360860
J Virol. 1979 Jun;30(3):767-70
480466