title: [Vitamin D and risk of fracture].
abstract: Although an increase in vitamin D has a small effect on bone mineral density, it has an influence on fracture prevention. This may be explained by a mechanism of improvement of bone strength that does not necessarily depend on bone mineral density. The level of serum 25 (OH) D is low in hip fracture patients compared with non-fracture controls, which suggests that a background of vitamin D insufficiency may be involved in hip fracture. Vitamin D acts on skeletal muscle and nerve cells, and it has been reported that this has an effect on fall prevention. Furthermore, recent reports suggest a role of vitamin D in cognitive function and in other tissues not involving bone.
authors.affiliation: Department of Physical Therapy, Faculty of Medical Technology, Niigata University of Health and Welfare/Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Science.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Sakuma
authors.forename: Takeo
authors.initials: T
authors.lastname: Oinuma
authors.forename: Naoto
authors.initials: N
authors.lastname: Endo
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D003072:Cognition Disorders / Q000209:etiology / Q000517:prevention & control; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006620:Hip Fractures / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D012306:Risk; D014808:Vitamin D Deficiency / Q000150:complications / Q000517:prevention & control