title: [Termination of pregnancy and placenta previa, interest of performing feticide before the labor induction?].
abstract: OBJECTIVE
  Study of maternal morbidity when termination of pregnancy (TOP) is associated with placenta previa and study of the interest of performing feticide before labor induction.
  
  
  METHODS
  This is a retrospective case control study with two groups of matched women: the case group (women with placenta previa) and the control group (women without placenta previa). Maternal morbidity have been studied and compared between the two groups and in the case group, between women who had feticide between labor induction and women who did not have feticide.
  
  
  RESULTS
  Between 1996 and 2009, we identified 15 cases of TOP with placenta previa (seven complete placentas previa and eight low lying placenta including partial and marginal placenta previa) who have been matched with 29 women. In the case group, eight women had feticide before labor induction, six women had no feticide and one woman had feticide the same day of labor induction. Maternal morbidity was increased in this group but without major complications (four hemorrhages during labor, two postpartum hemorrhages, four transfused patients and mean difference of hemoglobin level was 1.5 g/dl in the case group versus no hemorrhage during labor, no postpartum hemorrhage, no transfusion and mean difference of hemoglobin level was 0.5 g/dl in the control group; P<0.005). Performing feticide before labor induction allowed a non-significant reduction of mean loss of hemoglobin and of the number of women who needed transfusions.
  
  
  CONCLUSIONS
  A vaginal delivery in cases of TOP with placenta previa and even totally recovering seems a reasonable solution; performing feticide before labor induction could decrease loss of blood but further studies are needed.
authors.affiliation: Service de maternité Port-Royal, hôpital Cochin, AP-HP, université Paris Descartes, 123, boulevard du Port-Royal, 75014 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: du Passage
authors.forename: C
authors.initials: C
authors.lastname: Le Ray
authors.forename: G
authors.initials: G
authors.lastname: Grangé
authors.forename: D
authors.initials: D
authors.lastname: Cabrol
authors.forename: V
authors.initials: V
authors.lastname: Tsatsaris
mesh_terms: D000028:Abortion, Induced / Q000379:methods*; D000032:Abortion, Therapeutic / Q000379:methods; D000328:Adult; D001803:Blood Transfusion; D016022:Case-Control Studies; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007751:Labor, Induced; D010923:Placenta Previa / Q000628:therapy*; D006473:Postpartum Hemorrhage / Q000517:prevention & control; D011247:Pregnancy; D012189:Retrospective Studies
chemical_list: D006454:Hemoglobins