title: Somatic and affective anxiety symptoms and menopausal hot flashes.
abstract: OBJECTIVE
  Menopausal hot flashes have been associated with increased scores on measures of anxiety. Anxiety measures are typically composed of items measuring somatic and affective symptoms. Because hot flash symptoms are similar to symptoms of somatic anxiety, we wanted to examine the differential contribution of somatic anxiety and affective anxiety to hot flash scores.
  
  
  METHODS
  A total of 80 psychologically well-functioning postmenopausal women aged 50 to 64 years were administered the Zung Anxiety Index (ZAI), from which total score, somatic anxiety subscale score, and affective anxiety subscale score were calculated. The outcome measure was a hot flash score that incorporated both frequency and severity based on a 7-day diary. A linear regression analysis examined the association between hot flashes and the two anxiety subscales controlling for age, education, and sleep quality.
  
  
  RESULTS
  Higher score on somatic anxiety was significantly associated with higher hot flash score (P = 0.04), whereas the association with affective anxiety was not significant (P = 0.80). Higher total score on the ZAI was also significantly associated with higher hot flash score (P = 0.02).
  
  
  CONCLUSIONS
  These results suggest that the positive association between higher ZAI scores and hot flashes in recently postmenopausal women may be due to the overlap between the somatic manifestation of hot flashes and anxiety symptoms rather than to an affective anxiety disturbance. These results have potential implications for the care and treatment of postmenopausal women, but replication is required in other samples including women at different transition stages of menopause and women with psychiatric comorbidities.
authors.affiliation: Geriatric Research Unit, Brain Sciences, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Miriam A
authors.initials: MA
authors.lastname: Lermer
authors.forename: Angela
authors.initials: A
authors.lastname: Morra
authors.forename: Rahim
authors.initials: R
authors.lastname: Moineddin
authors.forename: Judith
authors.initials: J
authors.lastname: Manson
authors.forename: Jennifer
authors.initials: J
authors.lastname: Blake
authors.forename: Mary C
authors.initials: MC
authors.lastname: Tierney
mesh_terms: D001007:Anxiety / Q000503:physiopathology / Q000523:psychology*; D015331:Cohort Studies; D005260:Female; D019584:Hot Flashes / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008593:Menopause / Q000502:physiology / Q000523:psychology*; D008875:Middle Aged; D019964:Mood Disorders / Q000503:physiopathology / Q000523:psychology*; D011795:Surveys and Questionnaires