title: Hydrophilic polymer matrices in optical array sensing.
abstract: Whether in a glass chip or multi-well plate, differential array sensors are performed as a series of experiments and their output is compared among each other to obtain the differential signals evaluated by pattern recognition methods. To increase the practicality of performing a large number of experiments the sensor elements are often used as semi-wet gels displaying properties of both the solution and the solid state. Due to their semi-wet nature, such array sensors are easier to handle while offering a mechanical support, the affinity of hydrophilic matrices for water aids in analyte transport, and the tunable hydrophilic/hydrophobic nature of the matrices can be used adjusting the preference of the chemosensor membrane for different analytes.
authors.affiliation: Center for Photochemical Sciences, Bowling Green State University, Bowling Green, OH 43403, USA. pavel@bgsu.edu
authors.forename: Pavel
authors.initials: P
authors.lastname: Anzenbacher
authors.forename: Yuan-Li
authors.initials: YL
authors.lastname: Liu
authors.forename: Maria E
authors.initials: ME
authors.lastname: Kozelkova
mesh_terms: D006801:Humans; D020100:Hydrogels / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D046208:Microchip Analytical Procedures; D011108:Polymers / Q000737:chemistry*
chemical_list: D020100:Hydrogels; D011108:Polymers