[Effect of Bufeishenqingre decoction on bronchial hyperresponsiveness-induced cough].
OBJECTIVE
To evaluate the effect of traditional Chinese medicine preparations on bronchial hyperesponsiness (BHR)-induced cough.


METHODS
Sixty patients with cough due to BHR (shown by positive bronchial provocation test) were randomly divided into Chinese medicine group (n = 30) and control group (n = 30) to receive Bufeishenqingre decoction twice a day and 100 mg theophylline sustained-release capsules twice a day for one month, respectively. The changes of the clinical symptoms were observed during the treatment and bronchial infrared imaging was performed before and after the treatment.


RESULTS
The symptoms of patients in the Chinese medicine group were more effectively alleviated than those of the control group (P < 0.05). The difference in the temperature between the bronchial lesions and the surrounding normal mucosa changed more obviously in the Chinese medicine group (P < 0.01).


CONCLUSIONS
Bufeishenqingre decoction can relieve the symptoms and improve the abnormalities in infrared imaging of patients with BHR-induced cough.
Zhang
Yin
Y
Traditional Chinese Medicine Institute of General Hospital of PLA, Beijing 100853, China. 301zhangyin@sina.com
Yang
Ming-hui
MH
Dou
Yong-qi
YQ
Liu
Yi
Y
D000328:Adult; D016535:Bronchial Hyperreactivity / Q000150:complications* / Q000188:drug therapy*; D001985:Bronchial Provocation Tests; D001993:Bronchodilator Agents / Q000008:administration & dosage; D003371:Cough / Q000188:drug therapy* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D013806:Theophylline / Q000008:administration & dosage; D055815:Young Adult
D001993:Bronchodilator Agents; D004365:Drugs, Chinese Herbal; D013806:Theophylline