title: Facilitation of the development of fungiform taste buds by early intraoral acesulfame-K stimulation to mice.
abstract: The gustatory system is susceptible to anatomical modification by postnatal taste stimulations. This study investigated the effects of early intraoral infusion of acesulfame-K solution on the development of fungiform taste buds in mice. It was found that the acesulfame-K infusion increased the number, promoted the maturation, and enlarged the size of taste bud during the postnatal stages, compared with the age-matched controls. This provides fundamental and new information about the development of taste bud under normal and early acesulfame-K-stimulated conditions.
authors.affiliation: Sensory Science Laboratory, School of Bioscience and Food Engineering, Changshu Institute of Technology, Nansanhuan Road 99, Changshu, 215500 Jiangsu, People's Republic of China. zgh1970cn@gmail.com
authors.forename: Gen-Hua
authors.initials: GH
authors.lastname: Zhang
authors.forename: Meng-Ling
authors.initials: ML
authors.lastname: Chen
authors.forename: Si-Si
authors.initials: SS
authors.lastname: Liu
authors.forename: Yue-Hua
authors.initials: YH
authors.lastname: Zhan
authors.forename: Ying
authors.initials: Y
authors.lastname: Quan
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Qin
authors.forename: Shao-Ping
authors.initials: SP
authors.lastname: Deng
mesh_terms: D000284:Administration, Oral; D000818:Animals; D051379:Mice; D013650:Taste Buds / Q000187:drug effects* / Q000254:growth & development*; D013843:Thiazines / Q000008:administration & dosage*
chemical_list: D013843:Thiazines; C006362:acetosulfame