title: Patients' preference for number of embryos transferred during IVF/ICSI: a Nigerian experience.
abstract: BACKGROUND
  The Human Fertilization and Embryology Authority is considering limiting the number of embryos that can be transferred to single embryo per cycle as has been done in several European countries, with the aim of reducing the rate of multiple pregnancies and its attendant complications following in vitro fertilization (IVF) / Intracytoplasmic sperm injection (ICSI).
  
  
  OBJECTIVE
  To determine the number of embryos patients' attending a fertility clinic in Nigeria, would prefer transferred during IVF/ICSI.
  
  
  METHODS
  Fifty four consecutive female patients who underwent IVF/ICSI procedures between May 2006 and April 2007 at the Port Harcourt Fertility Centre, Rivers State were interviewed using structured questionnaires. They were informed of all the obstetric and perinatal complications of multiple pregnancies and the advantages and trend towards single embryo transfer and then asked to choose the number of embryos (one, two or three) they would prefer transferred assuming similar implantation rates. Each respondent was allowed to give reason(s) for their choice.
  
  
  METHODS
  Prospective, descriptive study.
  
  
  RESULTS
  Fifty one (94.4%) of the respondents preferred the transfer of multiple (2 or 3) embryos. Only three (5.6%) patients opted for single embryo transfer. Majority of the patients (31 or 60.8%) preferred multiple embryo transfer because of their desire for twins while twenty (39.2%) cited cost of IVF as their reason. Fifteen (29.4%) patients saw multiple pregnancies as a compensation for their long periods of infertility.
  
  
  CONCLUSIONS
  With the desire for twins and high poverty level in Nigeria, a policy of single embryo transfer might be difficult to implement. Health economic studies would be required to determine if the accumulative cost of taking care of twins/triplets is less, equal or outweighs the cost of several single embryo transfers.
authors.affiliation: Port Harcourt Fertility Centre, Prime Medical Consultants, Port Harcourt, Rivers State. judosca@yahoo.com
authors.forename: J E
authors.initials: JE
authors.lastname: Okohue
authors.forename: S O
authors.initials: SO
authors.lastname: Onuh
authors.forename: J I
authors.initials: JI
authors.lastname: Ikimalo
authors.forename: I
authors.initials: I
authors.lastname: Wada
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008875:Middle Aged; D009549:Nigeria; D057240:Patient Preference / Q000706:statistics & numerical data*; D011247:Pregnancy; D011446:Prospective Studies; D020554:Sperm Injections, Intracytoplasmic; D016896:Treatment Outcome; D055815:Young Adult