title: Smart hollow microspheres of chondroitin sulfate conjugates and magnetite nanoparticles for magnetic vector.
abstract: Smart hollow microspheres composed of vinyled-chondroitin sulfate conjugates (CSπ) and magnetite nanoparticles were obtained by the intermediate of a multiple emulsion in absence of a surfactant, attributable to stabilizing properties of the CS. It was formed an oil-water multiple emulsion in which the CS played a role as an anionic stabilizer for magnetite nanoparticles via complexation. Iron oxides were bonded to the microspheres by the formation of a complex of Fe(3+) ions on the crystalline phase with oxygen atoms at the carboxyl groups without their magnetic properties being affected. The average crystal size of embedded magnetite nanoparticles was approximately 16.5nm, indicative of a good dispersion in microspheres. Furthermore, the introduction of iron oxides resulted in microspheres with a higher diameter and a narrower particle size distribution.
authors.affiliation: Faculdade de Engenharia Química, Departamento de Sistemas Químicos e Informática DESQ, Universidade Estadual de Campinas, Rua Zeferino Vaz, CEP 13081-970 Campinas, SP, Brazil. marcos_guillherme@yahoo.com.br
authors.forename: Marcos R
authors.initials: MR
authors.lastname: Guilherme
authors.forename: Adriano V
authors.initials: AV
authors.lastname: Reis
authors.forename: Bruno R V
authors.initials: BR
authors.lastname: Alves
authors.forename: Marcos H
authors.initials: MH
authors.lastname: Kunita
authors.forename: Adley F
authors.initials: AF
authors.lastname: Rubira
authors.forename: Elias B
authors.initials: EB
authors.lastname: Tambourgi
mesh_terms: D002809:Chondroitin Sulfates / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D008280:Magnetics; D008863:Microspheres; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D004655:Emulsions; D002809:Chondroitin Sulfates; D052203:Ferrosoferric Oxide