Importance of precentral motor regions in human kinesthesia: a single case study.
Prompted by our neuroimaging findings in 60 normal people, we examined whether focal damage to the hand section of precentral motor regions impairs hand kinesthesia in a patient, and investigated brain regions related to recovery of kinesthetic function. The damage impaired contralateral kinesthesia. The peri-lesional cerebral motor region, together with the ipsilateral intermediate cerebellum, participated in the recovered kinesthetic processing. The study confirmed the importance of precentral motor regions in human kinesthesia, and indicated a contribution of the peri-lesional cerebral region in recovered kinesthesia after precentral damage, which conceptually fits with cases of recovery of motor function.
Naito
Eiichi
E
National Institute of Information and Communication Technology, Research Department 1, Kobe Advanced ICT Research Center, Kyoto, Japan. enaito@atr.jp
Matsumoto
Riki
R
Hagura
Nobuhiro
N
Oouchida
Yutaka
Y
Tomimoto
Hidekazu
H
Hanakawa
Takashi
T
D000368:Aged; D001931:Brain Mapping; D002531:Cerebellum / Q000033:anatomy & histology / Q000502:physiology; D006225:Hand; D006801:Humans; D007699:Kinesthesis; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology* / Q000473:pathology / Q000502:physiology*; D009068:Movement; D020127:Recovery of Function