TGF-ß in wound healing: a review.
TGF-ß, a growth factor involved in various stages of the wound healing process, exists in three different isoforms. Experimental models have shown these isoforms to be functionally different and one of them, TGF-ß3, has the potential to reduce scarring in clinical practice. This literature review explores the role of TGF- in wound healing, examining the research to date.
Douglas
H E
HE
Canniesburn Plastic Surgery Unit, Glasgow, UK. helendouglas@doctors.org.uk
D000818:Animals; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control; D004195:Disease Models, Animal; D006801:Humans; D010818:Practice Patterns, Physicians'; D017592:Skin Care; D016212:Transforming Growth Factor beta / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*; D014947:Wounds and Injuries / Q000150:complications / Q000188:drug therapy*
D016212:Transforming Growth Factor beta