RNAi knockdown of HdmX or Hdm2 leads to new insights into p53 signaling.
Berberich
Steven J
SJ
Biochemistry and Molecular Biology Department, Wright State University, Dayton, OH, USA. steven.berberich@wright.edu
D018797:Cell Cycle Proteins; D055785:Gene Knockdown Techniques; D006801:Humans; D009687:Nuclear Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D011401:Promoter Regions, Genetic; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D034622:RNA Interference; D015398:Signal Transduction; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism
D018797:Cell Cycle Proteins; C482775:MDM4 protein, human; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; C549565:YPEL3 protein, human; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2