title: Prolonged response to cytoreductive surgery and sunitinib in an elderly patient with synchronous multiple metastases from renal cell carcinoma.
abstract: One third of patients with renal cell cancer have metastatic disease at diagnosis. Until now the outcome of these patients has been poor due to the variable natural history of the disease and the lack of effective therapy. Multitargeted therapy of advanced renal cell cancer appears to be a better option than immunotherapy. We report the case of an elderly patient with skin, lung, bone and brain metastases and widespread intraabdominal disease treated with cytoreductive surgery and sunitinib, resulting in a prolonged response.
authors.affiliation: Department of Oncology, San Carlo Borromeo Hospital, Milan, Italy. locatellimc@hotmail.com
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Locatelli
authors.forename: Aurora
authors.initials: A
authors.lastname: Miedico
authors.forename: Adelaide
authors.initials: A
authors.lastname: D'Antona
authors.forename: Giovanni
authors.initials: G
authors.lastname: Longo
authors.forename: Matteo
authors.initials: M
authors.lastname: Maggioni
authors.forename: Augusto
authors.initials: A
authors.lastname: Maggioni
authors.forename: Pietro
authors.initials: P
authors.lastname: Tombolini
authors.forename: Donata
authors.initials: D
authors.lastname: Tabiadon
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D009392:Nephrectomy; D011758:Pyrroles / Q000627:therapeutic use*; D000077210:Sunitinib; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib