title: Duloxetine for the treatment of fibromyalgia.
abstract: This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.
authors.affiliation: Oregon Health and Science University, School of Nursing, Portland, OR 97239, USA. wrightch@ohsu.edu
authors.forename: Cheryl L
authors.initials: CL
authors.lastname: Wright
authors.forename: Scott D
authors.initials: SD
authors.lastname: Mist
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Ross
authors.forename: Kim D
authors.initials: KD
authors.lastname: Jones
mesh_terms: D002986:Clinical Trials as Topic; D000068736:Duloxetine Hydrochloride; D005356:Fibromyalgia / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D010146:Pain; D010147:Pain Measurement; D013876:Thiophenes / Q000627:therapeutic use*
chemical_list: D013876:Thiophenes; D000068736:Duloxetine Hydrochloride