title: Antimicrobial activity of single-walled carbon nanotubes: length effect.
abstract: This study investigated the effect of SWCNTs' length on their antimicrobial activity to bacterial cells in suspensions. Three different lengths of SWCNTs (<1 μm, 1-5 μm, and ∼5 μm) were tested. At same weight concentration, longer SWCNTs exhibited stronger antimicrobial activity. The fluorescence and SEM images revealed that the longer SWCNTs aggregated with bacterial cells more effectively, whereas short length SWCNTs tended to aggregate themselves without involving many bacterial cells. Moreover, longer SWCNTs exhibited more pronounced concentration-dependence and treatment time-dependence on their antimicrobial activity.
authors.affiliation: Biomanufacturing Research Institute and Technology Enterprises (BRITE) and Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina 27707, USA.
authors.forename: Cheenou
authors.initials: C
authors.lastname: Yang
authors.forename: Jaouad
authors.initials: J
authors.lastname: Mamouni
authors.forename: Yongan
authors.initials: Y
authors.lastname: Tang
authors.forename: Liju
authors.initials: L
authors.lastname: Yang
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence; D037742:Nanotubes, Carbon / Q000737:chemistry*; D012475:Salmonella / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors
chemical_list: D000890:Anti-Infective Agents; D037742:Nanotubes, Carbon