An IMP-Reset gate-based reusable and self-powered "smart" logic aptasensor on a microfluidic biofuel cell.
The development of microfluidic devices has been spurred by the desire to produce low-cost point-of-care diagnostics and environmental monitoring devices. By combining the adaptive behavior of microfluidic biofuel cells (micro-BFCs) self-regulating the power release with aptamer IMP logic, we constructed a novel IMP-Reset gate-based reusable and self-powered on-chip aptasensor, which can be used to logically determine the presence of one specific target in the absence of another target in complex physiological samples (such as human serum) in a single test.
Zhou
Ming
M
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P.R. China.
Chen
Chaogui
C
Du
Yan
Y
Li
Bingling
B
Wen
Dan
D
Dong
Shaojun
S
Wang
Erkang
E
D001483:Base Sequence; D001674:Bioelectric Energy Sources; D017931:DNA Primers; D004566:Electrodes; D044085:Microfluidics / Q000295:instrumentation*
D017931:DNA Primers