Possible link of a compositional change in intestinal microbiota with the anti-allergic effect of fructo-oligosaccharides in NC/jic mice.
Food allergy was induced in two groups of NC/jic mice. Mice fed frucuto-oligosaccharides showed fewer allergic symptoms than control diet-fed mice. The cecal microbiota compositions were clearly different between the two groups, and the difference was partly attributable to Clostridia possession. A possible link of the compositional change in intestinal micriobiota with the anti-allergic effect of fructo-oligosaccharides is suggested.
Inoue
Ryo
R
Laboratory of Animal Science, Kyoto Prefectural University, Kyoto, Japan.
Tsukahara
Takamitsu
T
Ueno
Kozo
K
Kitabayashi
Taeru
T
Ushida
Kazunari
K
D000818:Animals; D018926:Anti-Allergic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D003013:Clostridium / Q000302:isolation & purification; D004032:Diet; D005512:Food Hypersensitivity / Q000188:drug therapy / Q000382:microbiology*; D005632:Fructose; D007422:Intestines / Q000382:microbiology*; D054892:Metagenome; D051379:Mice; D008815:Mice, Inbred Strains; D009844:Oligosaccharides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*
D018926:Anti-Allergic Agents; D009844:Oligosaccharides; D005632:Fructose