title: Abnormal F-18 fluoride uptake in intracranial meningiomas on PET/CT.
abstract: The association between breast carcinoma and meningioma is a well-recognized phenomenon that may have important clinical implications, particularly in intracranial lesions. We report 2 cases of intracranial meningioma in adult women with a history of breast cancer, who were imaged with positron emission tomography/computed tomography (PET/CT) for evaluation of possible bone metastases. Whole-body F-18 fluoride PET demonstrated an intense intracranial focal radiotracer accumulation in both patients. Simultaneous CT showed a corresponding calcified space-occupying lesion, consistent with meningioma. Early and correct diagnosis of synchronous meningioma in F-18 fluoride bone scans might prevent relevant neurologic comorbidity.
authors.affiliation: Department of Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. t.derlin@uke.uni-hamburg.de
authors.forename: Thorsten
authors.initials: T
authors.lastname: Derlin
authors.forename: Janos
authors.initials: J
authors.lastname: Mester
authors.forename: Susanne
authors.initials: S
authors.lastname: Klutmann
mesh_terms: D000368:Aged; D001692:Biological Transport; D005260:Female; D005459:Fluorides / Q000378:metabolism*; D005462:Fluorine Radioisotopes / Q000378:metabolism; D006801:Humans; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*; D008579:Meningioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D005462:Fluorine Radioisotopes; D005459:Fluorides