Irritable bowel syndrome and small intestinal bacterial overgrowth.
In the last 3 decades, there has been a growing appreciation for the role of gut bacteria in gastrointestinal disease. Although inflammatory bowel disease and peptic ulcer disease have established a role for gut bacteria for more than 20 years, there is now increasing evidence that intestinal bacteria may play a role in irritable bowel syndrome as well. In this review, the current evidence for bacteria in irritable bowel syndrome will be examined.
Yamini
David
D
GI Motility Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Pimentel
Mark
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019317:Evidence-Based Medicine; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D007421:Intestine, Small / Q000187:drug effects / Q000382:microbiology*; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D005765:Gastrointestinal Agents