title: Lateralization of speech production starts in sensory cortices--a possible sensory origin of cerebral left dominance for speech.
abstract: Speech production is a left-lateralized brain function, which could arise from a left dominance either in speech executive or sensory processes or both. Using functional magnetic resonance imaging in healthy subjects, we show that sensory cortices already lateralize when speaking is intended, while the frontal cortex only lateralizes when speech is acted out. The sequence of lateralization, first temporal then frontal lateralization, suggests that the functional lateralization of the auditory cortex could drive hemispheric specialization for speech production.
authors.affiliation: Brain Imaging Center and Department of Neurology, Goethe University Frankfurt, 60528 Frankfurt, Germany. c.kell@em.uni-frankfurt.de.
authors.forename: Christian Alexander
authors.initials: CA
authors.lastname: Kell
authors.forename: Benjamin
authors.initials: B
authors.lastname: Morillon
authors.forename: Frederique
authors.initials: F
authors.lastname: Kouneiher
authors.forename: Anne-Lise
authors.initials: AL
authors.lastname: Giraud
mesh_terms: D000328:Adult; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D013003:Somatosensory Cortex / Q000502:physiology*; D013060:Speech / Q000502:physiology*; D055815:Young Adult