title: An analysis of children with brucellosis associated with isolated thrombocytopenia.
abstract: Hematologic abnormalities of mild anemia and leucopenia have been frequently associated with acute brucellosis, but thrombocytopenia are less frequently seen. In the present study, we documented 5 (2.6%) isolated thrombocytopenic patients with the manifestations of brucellosis observed during the course of active infection. Five (2.6%) patients, 4 boys and 1 girl, with ages ranging from 2 to 14 years, had isolated thrombocytopenic at diagnosis. In 5 (2.6%) patients, platelet counts ranged from 39,000 to 120,000/mm(3). Tube agglutination tests for brucellosis were positive for all patients (1/160-1/1280). All patients recovered completely, and their thrombocytopenia returned to normal by 2 to 4 weeks after antibiotic treatment of brucellosis. In our study, we present 5 patients with Brucella-induced thrombocytopenia mimicking idiopathic thrombocytopenic purpura to emphasize the isolated thrombocytopenia and the resolution of thrombocyte counts following treatment of brucellosis.
authors.affiliation: Department of Pediatric Hematology, Yuzuncu Yil University, Van, Turkey. drsinanakbayram@gmail.com
authors.forename: Sinan
authors.initials: S
authors.lastname: Akbayram
authors.forename: Murat
authors.initials: M
authors.lastname: Dogan
authors.forename: Cihangir
authors.initials: C
authors.lastname: Akgun
authors.forename: Erdal
authors.initials: E
authors.lastname: Peker
authors.forename: Mehmet
authors.initials: M
authors.lastname: Parlak
authors.forename: Ahmet Faik
authors.initials: AF
authors.lastname: Oner
mesh_terms: D000293:Adolescent; D002006:Brucellosis / Q000097:blood* / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000175:diagnosis; D013921:Thrombocytopenia / Q000097:blood / Q000188:drug therapy / Q000382:microbiology*