Gold-catalyzed cascade annulations of 2-(ynol)aryl aldehydes: facile synthesis of benzochromanes and benzobicyclo[n.3.1]acetals.
Gold-catalyzed reactions of 2-(ynol)aryl aldehydes were investigated. Benzochromanes were obtained from the reaction when AuCl(3) was employed as the catalyst, whereas benzobicyclo[n.3.1]acetals were produced when triazole-gold was employed as the catalyst. Plausible mechanisms are discussed.
Liu
Le-Ping
LP
Department of Chemistry, University of Louisville, Louisville, Kentucky 40292, USA. leping.liu@louisville.edu
Hammond
Gerald B
GB