title: [Total pelvic exenteration].
abstract: Over the last decades total pelvic exenteration (TPE) has evolved into an established and safe surgical technique for locally advanced pelvic malignancies. Depending on the type of cancer 5 year overall survival rates of up to 66% and a satisfactory postsurgical quality of life have been reported. Currently infiltration of the pelvic side wall and resectable metastases are not necessarily a contraindication to a curative approach; furthermore, TPE can also be useful in palliative surgery. In locally recurrent rectal cancer TPE is the treatment of choice if the tumor is deemed resectable. A multidisciplinary diagnostic and therapeutic approach is of utmost importance, hence patients should be treated in specialized centers.
authors.affiliation: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie,Sektion Chirurgische Onkologie, Chirurgische Universitätsklinik, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Heger
authors.forename: M
authors.initials: M
authors.lastname: Koch
authors.forename: M W
authors.initials: MW
authors.lastname: Büchler
authors.forename: J
authors.initials: J
authors.lastname: Weitz
mesh_terms: D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010166:Palliative Care / Q000379:methods; D010385:Pelvic Exenteration / Q000379:methods* / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology; D019651:Plastic Surgery Procedures / Q000379:methods*; D012004:Rectal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D013518:Surgery, Plastic / Q000379:methods; D015996:Survival Rate; D014513:Ureter / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*