title: Treatment of concurrent metastatic renal cell carcinoma and chronic myelogenous leukemia--easier said than done? A case report.
abstract: Treating two active malignancies concurrently can be exceedingly difficult. Complications can occur from the different treatment regimens, especially if they share common targets, and the progressing diseases can make managing treatment side-effects even more challenging. We report a case of a patient with coexisting CML and mRCC who progressed on multiple lines of mRCC therapy while experiencing significant dose limiting side-effects.
authors.affiliation: Department of Pharmacy, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. fhsalnajjar@gmail.com
authors.forename: Fouad
authors.initials: F
authors.lastname: Al-Najjar
authors.forename: Anthony
authors.initials: A
authors.lastname: Jarkowski
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents