A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin-streptavidin system.
Luminol functionalized gold nanoparticles were used as labels for electrochemiluminescence signal amplification and an ultrasensitive, highly selective, convenient, low cost DNA detection strategy was developed.
Chai
Ying
Y
Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China.
Tian
Dayong
D
Wang
Wei
W
Cui
Hua
H
D001483:Base Sequence; D015374:Biosensing Techniques / Q000191:economics / Q000379:methods*; D001710:Biotin / Q000737:chemistry; D004247:DNA / Q000032:analysis*; D004563:Electrochemistry / Q000191:economics / Q000379:methods; D006046:Gold / Q000737:chemistry*; D006801:Humans; D008163:Luminescent Measurements / Q000191:economics / Q000379:methods*; D008165:Luminol / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D012680:Sensitivity and Specificity; D044967:Serum / Q000737:chemistry; D019809:Streptavidin / Q000737:chemistry
D008165:Luminol; D001710:Biotin; D006046:Gold; D004247:DNA; D019809:Streptavidin