Selective α-defluorination of polyfluorinated esters and amides using SmI2/Et3N/H2O.
SmI(2)/H(2)O promotes selective α-monodefluorinations, while addition of an amine results in complete α-defluorination reactions.
Wettergren
Jenny
J
Department of Chemistry, University of Gothenburg, Kemivägen 10, SE-412 96 Göteborg, Sweden.
Ankner
Tobias
T
Hilmersson
Göran
G
D000577:Amides / Q000737:chemistry*; D000588:Amines / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D005021:Ethylamines / Q000737:chemistry*; D054879:Halogenation; D007454:Iodides / Q000737:chemistry*; D012493:Samarium / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D000577:Amides; D000588:Amines; D004952:Esters; D005021:Ethylamines; D007454:Iodides; D014867:Water; D012493:Samarium; C409809:samarium diiodide; C016162:triethylamine