Phytotoxic activity of flavonoids from Dicranostyles ampla.
Crude extracts from over 16 species of plants from the family Convolvulaceae were evaluated for phytotoxic activity against Agrostis stolonifera (bentgrass) and Lactuca sativa (lettuce) at 1000 microg/mL. Ethanol extracts of Dicranostyles ampla Ducke were among the most active of those species tested. Systematic bioassay-guided fractionation of the ethanol extract of the aerial parts from this species was performed to identify specifically the phytotoxic compounds. Two phytotoxic flavonoids, dihydromyricetin (1) and myricetin-3-O-alpha-rhamnoside or myricetrin (2), were found to be responsible for much of the activity of the extract as a whole in the A. stolonifera and L. sativa bioassay. In a Lemna paucicostata bioassay, 1 and 2 had no activity at 100 microM.
Castro
Amaya
A
IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain. amaya.castro@iqac.csic.es
Cantrell
Charles L
CL
Hale
Amber L
AL
Duke
Stephen O
SO
D031703:Agrostis / Q000187:drug effects*; D027722:Convolvulaceae / Q000737:chemistry*; D005419:Flavonoids / Q000633:toxicity*; D018545:Lactuca / Q000187:drug effects*; D010936:Plant Extracts / Q000633:toxicity*
D005419:Flavonoids; D010936:Plant Extracts