title: Incidence of influenza virus infection in early infancy: a prospective study in South Asia.
abstract: We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.
authors.affiliation: Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Henkle
authors.forename: Mark C
authors.initials: MC
authors.lastname: Steinhoff
authors.forename: Saad B
authors.initials: SB
authors.lastname: Omer
authors.forename: Eliza
authors.initials: E
authors.lastname: Roy
authors.forename: Shams E
authors.initials: SE
authors.lastname: Arifeen
authors.forename: Rubhana
authors.initials: R
authors.lastname: Raqib
authors.forename: Monica
authors.initials: M
authors.lastname: McNeal
authors.forename: Robert F
authors.initials: RF
authors.lastname: Breiman
authors.forename: William J
authors.initials: WJ
authors.lastname: Moss
authors.forename: K
authors.initials: K
authors.lastname: Zaman
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D001208:Asia / Q000453:epidemiology; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007251:Influenza, Human / Q000453:epidemiology*; D008297:Male; D011446:Prospective Studies; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral