title: [Functional and molecular imaging of breast tumors].
abstract: Molecular imaging is concerned with the presentation, description and quantification of biological and physiological processes at the cellular and molecular level. Most recently molecular imaging has started to become established in breast diagnostics. This review article will give an overview of procedures which are either in the preclinical development stage or which have already become clinically established. Molecular nuclear medicine breast imaging (breast-specific gamma imaging [BSGI] and positron emission mammography [PEM]) together with specific radiotracers and contrast media will be discussed. The possibilities for magnetic resonance imaging in functional (DWI) and metabolic (MRSI) imaging of breast lesions and the combined application of nuclear medicine and magnetic resonance imaging (PET/MRI) will be explained. Furthermore, an overview on the preclinical procedure and the possible clinical applications of optical and photoacoustic imaging will be given.
authors.affiliation: Abteilung für Allgemeine Radiologie und Kinderradiologie, Division für Molekulare und Gender-Bildgebung, Universitätsklinik für Radiodiagnostik, Medizinische Universität Wien, Währinger Gürtel 18-20, A-1090 Wien, Deutschland.
authors.forename: K
authors.initials: K
authors.lastname: Pinker
authors.forename: P
authors.initials: P
authors.lastname: Brader
authors.forename: G
authors.initials: G
authors.lastname: Karanikas
authors.forename: K
authors.initials: K
authors.lastname: El-Rabadi
authors.forename: W
authors.initials: W
authors.lastname: Bogner
authors.forename: S
authors.initials: S
authors.lastname: Gruber
authors.forename: M
authors.initials: M
authors.lastname: Reisegger
authors.forename: S
authors.initials: S
authors.lastname: Trattnig
authors.forename: T H
authors.initials: TH
authors.lastname: Helbich
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D003287:Contrast Media / Q000008:administration & dosage; D003952:Diagnostic Imaging / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D025202:Molecular Diagnostic Techniques / Q000295:instrumentation / Q000379:methods*; D009367:Neoplasm Staging; D057285:Precision Medicine / Q000379:methods; D011237:Predictive Value of Tests; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media