title: Covered-stent treatment of coronary aneurysm after drug-eluting stent placement: case report and literature review.
abstract: Most commonly, coronary artery aneurysms are secondary to atherosclerosis, but cases have been reported in patients who have vasculitis or tissue disorders, and in patients who have undergone interventional procedures. However, over the past few years, an increasing number of cases of coronary artery aneurysms after drug-eluting stent implantation have been reported. The exact mechanism is unknown. Experimental animal studies have shown that both the active drug and the polymer coating, under certain circumstances, might cause progressive luminal dilation, positive vascular remodeling, and aneurysmal formation. Complications like rupture, thrombosis, embolization, myocardial infarction, and even sudden death have been reported. Treatment options vary from aggressive surgical ligation of the aneurysm, in union with distal bypass surgery, to percutaneous implantation of a covered stent or conservative medical management with continued antiplatelet therapy. Currently, there is no consensus on an ideal approach to treating coronary artery aneurysm after drug-eluting stent implantation. Polytetrafluoroethylene-covered stents, easy and rapid to deploy, have emerged as a newer option. We report a case of coronary artery aneurysm at the site of a previous drug-eluting stent. The lesion was successfully treated with a polytetrafluoroethylene-covered stent.
authors.affiliation: Departments of Internal Medicine, St Joseph's Regional Medical Center, Paterson, New Jersey 07503, USA.
authors.forename: Sharad
authors.initials: S
authors.lastname: Bajaj
authors.forename: Rupen
authors.initials: R
authors.lastname: Parikh
authors.forename: Aiman
authors.initials: A
authors.lastname: Hamdan
authors.forename: Mahesh
authors.initials: M
authors.lastname: Bikkina
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation*; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D054855:Drug-Eluting Stents; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011474:Prosthesis Design; D015607:Stents; D016896:Treatment Outcome
chemical_list: D011138:Polytetrafluoroethylene