Facilitation of the development of fungiform taste buds by early intraoral acesulfame-K stimulation to mice.
The gustatory system is susceptible to anatomical modification by postnatal taste stimulations. This study investigated the effects of early intraoral infusion of acesulfame-K solution on the development of fungiform taste buds in mice. It was found that the acesulfame-K infusion increased the number, promoted the maturation, and enlarged the size of taste bud during the postnatal stages, compared with the age-matched controls. This provides fundamental and new information about the development of taste bud under normal and early acesulfame-K-stimulated conditions.
Zhang
Gen-Hua
GH
Sensory Science Laboratory, School of Bioscience and Food Engineering, Changshu Institute of Technology, Nansanhuan Road 99, Changshu, 215500 Jiangsu, People's Republic of China. zgh1970cn@gmail.com
Chen
Meng-Ling
ML
Liu
Si-Si
SS
Zhan
Yue-Hua
YH
Quan
Ying
Y
Qin
Yu-Mei
YM
Deng
Shao-Ping
SP
D000284:Administration, Oral; D000818:Animals; D051379:Mice; D013650:Taste Buds / Q000187:drug effects* / Q000254:growth & development*; D013843:Thiazines / Q000008:administration & dosage*
D013843:Thiazines; C006362:acetosulfame