Prevalence of extramucosal fungal elements in sinonasal polyposis: a mycological and pathologic study in an Egyptian population.
OBJECTIVE
The objective of the study was to define the true incidence of fungal elements in the nasal and sinus mucous in cases of chronic rhinosinusitis (CRS) with bilateral polyposis compared with normal controls-in an Egyptian African population-via mycological and histologic techniques.


METHODS
This study was conducted prospectively on 100 patients with the clinical diagnosis of CRS with bilateral nasal polyposis. Fifty volunteers with no history of nasal or paranasal sinus disease served as a control group.


CONCLUSIONS
The postulated criteria for the diagnosis of allergic fungal sinusitis were present in 92% of CRS with polyposis, suggesting that fungi are involved in the disease process of most CRS patients.
Bassiouny
Ahmed
A
Faculty of Medicine, Department of Otolaryngology, Cairo University, 7 El Shaheed Mahmoud Afifi St., Almaza, Cairo, Egypt.
Ragab
Ashraf
A
Attia
Abdel Fattah
AF
Atef
Ahmed
A
Hafez
Nadia
N
Ayad
Essam
E
Sameer
Hany
H
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D004534:Egypt / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D055556:Nasal Lavage; D009297:Nasal Mucosa / Q000382:microbiology* / Q000473:pathology; D009298:Nasal Polyps / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D010256:Paranasal Sinuses / Q000382:microbiology* / Q000473:pathology; D015995:Prevalence; D011446:Prospective Studies; D012220:Rhinitis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D012852:Sinusitis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D055815:Young Adult