The Relationship between Lung Function and Metabolic Syndrome in Obese and Non-Obese Korean Adult Males.
BACKGROUND
The existence of an association between lung function and metabolic syndrome (MetS) has been debated in cases involving non-obese subjects. To address this debate, we performed a cross-sectional study to investigate the association between lung function and MetS in both obese and non-obese populations.


METHODS
The present study consisted of a total of 1,951 Korean male subjects. In this study group, we investigated relationships between lung function and MetS risk factors such as fasting serum glucose, systolic blood pressure (SBP), insulin resistance index, waist circumference (WC), and hemoglobin A(1C) level.


RESULTS
Forced vital capacity (FVC) values were significantly lower in the MetS group compared with those of the non-MetS group. In both non-obese (body mass index [BMI] < 25 kg/m(2)) and obese subjects (BMI ≥ 25 kg/m(2)), fasting serum glucose, hemoglobin A(1C) level, insulin resistance index, SBP, WC, and the prevalences of diabetes and MetS were significantly higher in subjects in the lowest FVC quartile compared with those in the highest FVC quartile. Odds ratios for the presence of MetS risk factors, after adjusting for age and height, ranged from 1.21 to 1.39 (P < 0.01) for a one standard deviation decrease in FVC.


CONCLUSIONS
The results of our study suggest that decreased vital capacity in Korean adult male subjects is associated with MetS, irrespective of obesity.
Kim
Soo Kyoung
SK
Division of Endocrinology and Metabolism, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hur
Kyu Yeon
KY
Choi
Yoon Ho
YH
Kim
Sun Wook
SW
Chung
Jae Hoon
JH
Kim
Hee Kyung
HK
Lee
Moon-Kyu
MK
Min
Yong-Ki
YK
Kim
Kwang-Won
KW
Kim
Jae Hyeon
JH