[Current options for the treatment of osteoporosis].
The primary aim of osteoporosis treatment is prevention of osteoporotic fractures. The main factors in the development of these fractures are mechanic resistance of the bone and the bone quality. The importance of risk factor identification increases and it is important to consider the structural analysis of the hip-bone when evaluating and deciding whether to prescribe antiresorptive or osteoanabolic drugs or whether to just modify calcium and vitamin D intake. Various options are currently available for the pharmacological treatment of osteoporosis: calcium and vitamin D supplementation together with aminobisphosphonates, or osteoanabolic treatment with parathormone derivatives; monoclonal antibody to RANKL denosumab will also soon become available.
Vyskocil
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Osteocentrum FN Plzen, II. interní kliniky LF UK a FN Plzen. vyskocil@fnplzen.cz
D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012307:Risk Factors