Kidney transplantation from older donors: proceed with caution.
Kidney transplantation from living and deceased donors above age 60 increased in recent years in response to organ shortage. With careful screening, short-term follow-up of living elderly donors demonstrated stable remaining kidney function even in those with mild and controlled hypertension. The need for confirmation of long-term safety is heightened by the report by Tan et al. of a high prevalence of nephrosclerotic changes in these donors and evidence for a decreased number of glomeruli in elderly deceased donors.
Abulezz
Sameh R
SR
Department of Nephrology, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA. abulezzsamehr@uams.edu
D000368:Aged; D000375:Aging / Q000502:physiology*; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008875:Middle Aged; D014019:Tissue Donors