Acute and chronic Chlamydia pneumoniae infection in pregnancy complicated with preeclampsia.
OBJECTIVE
To investigate whether Chlamydia pneumoniae (Cp) infection is more common in women whose current pregnancy is complicated with preeclampsia (PE) as compared to pregnant women without PE.


METHODS
Thirty pregnant women with PE and 30 pregnant women without PE were studied between 29 and 30 weeks of gestation. The presence of an acute or chronic Cp infection was determined by the estimations of serum IgG, IgM, and IgA Cp antibodies.


RESULTS
None of the women were diagnosed as having acute Cp infection. Prevalence of chronic Cp infection was 53 and 66% in the PE and control groups, respectively (X(2), p = 0.068).


CONCLUSIONS
Chronic Cp infection is not more common in women whose pregnancy is complicated with PE as compared to pregnant women without PE. Therefore, no association between Cp infection and PE can be established.
Chrisoulidou
Alexandra
A
Unit of Endocrinology and Endocrine Oncology, Theagenio Hospital, Thessaloniki, Greece. alexri@otenet.gr
Goulis
Dimitrios G
DG
Iliadou
Paschalia K
PK
Dave
Jitendra R
JR
Bili
Helen
H
Simms
Carol
C
Redman
Christopher W G
CW
Williamson
Catherine
C
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D002690:Chlamydia Infections / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D016993:Chlamydophila pneumoniae / Q000276:immunology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000453:epidemiology* / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D015995:Prevalence; D012720:Severity of Illness Index
D000907:Antibodies, Bacterial