title: Enantiopure 1,2-bis(tert-butylmethylphosphino)benzene as a highly efficient ligand in rhodium-catalyzed asymmetric hydrogenation.
abstract: An electron-rich P-stereogenic bisphosphine ligand named "BenzP*" was conveniently prepared from o-dibromobenzene and enantiopure tert-butylmethylphosphine-borane. Its rhodium complex exhibited excellent enantioselectivities of up to 99.9% and high catalytic activity of up to 10,000 h(-1) TOF in asymmetric hydrogenations of various functionalized alkenes.
authors.affiliation: Organic R&D Department, Nippon Chemical Industrial Co., Ltd., Kameido, Koto-ku, Tokyo 136-8515, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Tamura
authors.forename: Masashi
authors.initials: M
authors.lastname: Sugiya
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Akira
authors.initials: A
authors.lastname: Yanagisawa
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Imamoto