[Study on the epidemiological of rotavirus diarrhea in Lulong in 2008-2009].
OBJECTIVE
To analyze the feature of epidemiological of rotavirus diarrhea in Lulong county, Hebei province.


METHODS
426 stool specimens were collected from inpatant with acute diarrhea from children less than 5 years old. Rotavirus-positive specimens were identified by ELISA kit. G/P typing assays were confirmed with multiplex seminested RT-PCR.


RESULTS
Rotavirus was detected in 202 of 426 (47.42%) specimens. Genotyping of rotavirus showed that G3 was predominant (57.9%), followed by Gmix (16.3%), G9 (14.9% ), G1 (7.9%), G4 (1%), G2 (0.5%), P-genotyping showed that P [8], Pmix, P [4], P [9], type were found in 58.4%, 28.7%, 6.9% and 1% respectively. The most common G/P combination identified was G3P [8].


CONCLUSIONS
Group A rotaviruses was a major pathogen of diarrhea in Children in Lulong. G3P [8] was the predominant type in 2009, Gmix and Pmix abound, and G9 serotypes has become the second predominant after G3 strain in the region.
Li
Dan-Di
DD
State Key Laboratory of Molecular Virology and Genetic Engineering, Beijing 100052, China.
Yu
Qiu-Li
QL
Qi
Shun-Xiang
SX
Xie
Yun
Y
Zhang
Qing
Q
Cui
Shu-Xian
SX
Duan
Zhao-Jun
ZJ
D017677:Age Distribution; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology; D012621:Seasons