title: Palladium-catalyzed C-H functionalization of heteroarenes with aryl bromides and chlorides.
abstract: Palladium-catalyzed C-H arylation of electron-enriched heteroarenes with aryl bromides and aryl chlorides proceeds in the presence of LiO-t-Bu as a base. The reaction allows one-pot synthesis of differently substituted 2,5-diarylthiazole with the same catalyst system by switching the solvent and the amount of base.
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tamba
authors.forename: Youhei
authors.initials: Y
authors.lastname: Okubo
authors.forename: Shota
authors.initials: S
authors.lastname: Tanaka
authors.forename: Daiki
authors.initials: D
authors.lastname: Monguchi
authors.forename: Atsunori
authors.initials: A
authors.lastname: Mori
mesh_terms: D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D006842:Hydrocarbons, Brominated; D006843:Hydrocarbons, Chlorinated; D009942:Organometallic Compounds; D013844:Thiazoles; D010165:Palladium