title: [Bone scanning with sodium 18F-fluoride PET and PET/CT. German guideline Version 1.0.].
abstract: In nuclear medicine, bone scanning is based on the principle of scintigraphy using bone-seeking radiopharmaceuticals which accumulate in sites of increased bone formation. From a historical point of view, (18)F-fluoride was one of the first osteotropic tracers which was replaced by (99m)Tc-labelled polyphosphonates. With the development of modern PET equipment the superior diagnostic performance of (18)F-fluoride PET for the detection and characterization of osseous lesions was proven in comparison to conventional bone scanning. Recently, its importance as a substitute of conventional skeletal scintigraphy increased in a time with limited availability of (99)Mo/(99m)Tc. To ensure health care during this period, (18)F-fluoride PET currently became part of common outpatient care. This guideline comprehends recommendations on indications, protocols, interpretation and reporting of (18)F-fluoride PET and PET/CT.
authors.affiliation: Klinik für Nuklearmedizin, Universitätsklinikum des Saarlandes, 66421 Homburg/Saar. Dirk.Hellwig@uks.eu
authors.forename: D
authors.initials: D
authors.lastname: Hellwig
authors.forename: B-J
authors.initials: BJ
authors.lastname: Krause
authors.forename: H
authors.initials: H
authors.lastname: Schirrmeister
authors.forename: M
authors.initials: M
authors.lastname: Freesmeyer
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005459:Fluorides; D019788:Fluorodeoxyglucose F18; D005858:Germany; D006801:Humans; D008982:Molybdenum; D049268:Positron-Emission Tomography / Q000379:methods*; D012969:Sodium Fluoride; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D019788:Fluorodeoxyglucose F18; D008982:Molybdenum; D012969:Sodium Fluoride; D005459:Fluorides