Pd-catalyzed three-component coupling of N-tosylhydrazone, terminal alkyne, and aryl halide.
A Pd-catalyzed three-component reaction of N-tosylhydrazone, terminal alkyne, and aryl halide follows a mechanism involving a sequence of Pd carbene migratory insertion-transmetalation-reductive elimination, leading to the formation of one sp(2)-sp(3) C-C bond and one sp-sp(3) C-C bond.
Zhou
Lei
L
Beijing National Laboratory of Molecular Sciences, College of Chemistry, Peking University, Beijing 100871, China.
Ye
Fei
F
Zhang
Yan
Y
Wang
Jianbo
J
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D006835:Hydrazones / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D000480:Alkynes; D006835:Hydrazones; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D010165:Palladium