title: Mn(0)-mediated chemoselective reduction of aldehydes. Application to the synthesis of α-deuterioalcohols.
abstract: A mild, simple, safe, chemoselective reduction of different kinds of aldehydes to the corresponding alcohols mediated by the Mn dust/water system is described. In addition to this, the use of D(2)O leads to the synthesis of α-deuterated alcohols and constitutes an efficient, inexpensive alternative for the preparation of these compounds.
authors.affiliation: Department of Organic Chemistry, Faculty of Sciences, University ofGranada, C. U. Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: Tania
authors.initials: T
authors.lastname: Jiménez
authors.forename: Elisa
authors.initials: E
authors.lastname: Barea
authors.forename: J Enrique
authors.initials: JE
authors.lastname: Oltra
authors.forename: Juan M
authors.initials: JM
authors.lastname: Cuerva
authors.forename: José
authors.initials: J
authors.lastname: Justicia
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000447:Aldehydes; D008345:Manganese