title: Vaccines to antibodies: grow up!
abstract: Through a process called affinity maturation, all of the HIV-specific antibodies identified so far have accumulated multiple mutations, some of which are required for them to bind to and neutralize HIV. Researchers are now beginning to grapple with what this means for vaccine design.
authors.forename: Andreas
authors.initials: A
authors.lastname: von Bubnoff
mesh_terms: D016915:AIDS Vaccines / Q000276:immunology*; D057134:Antibodies, Neutralizing / Q000276:immunology; D000915:Antibody Affinity; D015483:HIV Antibodies / Q000276:immunology*; D006801:Humans
chemical_list: D016915:AIDS Vaccines; D057134:Antibodies, Neutralizing; D015483:HIV Antibodies