title: Distribution of filamentous fungi causing invasive fungal disease at the Haematological Unit, Hospital de Clínicas de Porto Alegre, Brazil.
abstract: Very limited data are available in the literature to elucidate the aetiology of invasive mould infections in Latin America. Here we report that Aspergillus species caused only half of such cases in a cohort study conducted over 21 months in a university hospital in Porto Alegre, Southern Brazil. Fusarium spp. were the second most prevalent moulds (20.7%), followed by Zygomycetes (13.8%). The importance of obtaining local epidemiological data for adequately guiding empirical antifungal therapy is reinforced.
authors.affiliation: Microbiology Unit Section, Clinical Patology Services, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Valério Rodrigues
authors.initials: VR
authors.lastname: Aquino
authors.forename: Emanuelle Bergonsi
authors.initials: EB
authors.lastname: Verçosa
authors.forename: Gustavo
authors.initials: G
authors.lastname: Falhauber
authors.forename: Luciano Werle
authors.initials: LW
authors.lastname: Lunardi
authors.forename: Lucia
authors.initials: L
authors.lastname: Silla
authors.forename: Alessandro Comarú
authors.initials: AC
authors.lastname: Pasqualotto
mesh_terms: D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D001938:Brazil; D015331:Cohort Studies; D005260:Female; D005658:Fungi / Q000145:classification* / Q000302:isolation & purification; D006785:Hospitals, University; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology* / Q000517:prevention & control; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole