Diels-Alder reactions of cyclic isoimidium salts.
Diels-Alder reactions of cyclic isoimidium salts are described. The corresponding cycloadducts are obtained with high regio- and stereoselectivity. The use of homochiral cyclic isoimidium salts delivers cycloadducts with excellent diastereoselectivity (>99:1) that can be efficiently converted to enantiomerically pure lactones.
Boeckman
Robert K
RK
Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, USA. rkb@rkbmac.chem.rochester.edu
Miller
Yan
Y
Ryder
Todd R
TR
D003500:Cyclization; D007094:Imides / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D007094:Imides