title: [Physiologic skin changes in pregnancy].
abstract: BACKGROUND
  Pregnancy is a period of hormonal, immunological, metabolic and vascular changes. Some of them are considered to be physiologic, but others are real diseases specific or not of pregnancy. The aim of our study is to present the epidemiological and clinical physiologic dermatological changes of pregnancy.
  
  
  METHODS
  We present a transversal monocentric study. One hundred pregnant women attending the department of dermatology of the La Rabta hospital were enrolled. Systematic detailed cutaneous examination was performed by a dermatologist to look for a physiologic skin changes.
  
  
  RESULTS
  The mean age was 29 years [20-46 years]. Pigmentary changes were the most preponderant (93%), dominated by the areolar region pigmentation (77%). The glandular changes were noted in 75% of cases. The vascular modifications were observed in 77% of pregnant women. Of these, gingival hyperemia was the most common (46%). Others cutaneous changes were less frequent (stria distensae 45%, nevi changes 35%, molluscum gravidarum 10%).
  
  
  CONCLUSIONS
  The physiologic cutaneous changes during pregnancy are numerous. Our study confirms the frequency and the variability of these modifications. The pigmentary changes were the most common finding.
authors.affiliation: Hôpital La Rabta, service de dermatologie, Jabbari, 1007 Tunis, Tunisia.
authors.forename: Aida
authors.initials: A
authors.lastname: Zerouali
authors.forename: Inès
authors.initials: I
authors.lastname: Zaraa
authors.forename: Sondes
authors.initials: S
authors.lastname: Trojjet
authors.forename: Dalenda
authors.initials: D
authors.lastname: El Euch
authors.forename: Mohamed Iadh
authors.initials: MI
authors.lastname: Azeiez
authors.forename: Mourad
authors.initials: M
authors.lastname: Mokni
authors.forename: Faouzia
authors.initials: F
authors.lastname: Zouari
authors.forename: Amel
authors.initials: A
authors.lastname: Ben Osman
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy / Q000502:physiology*; D012879:Skin Physiological Phenomena; D055815:Young Adult