Holmes-Adie syndrome associated with high altitude pulmonary edema and low chemo-responsiveness to hypoxia.
A 63-year-old patient with Holmes-Adie syndrome presented an altered peripheral chemoreflex and suffered from high altitude pulmonary edema, suggesting an alteration of sensitive afferent fibers from the peripheral chemoreceptors. Chemo-responsiveness to hypoxia should be explored before any exposure to moderate altitude in Holmes-Adie patients.
Richalet
Jean-Paul
JP
Service de Physiologie, Explorations Fonctionnelles et Médecine du Sport, AP-HP, Hôpital Avicenne, Bobigny, France. richalet@smbh.univ-paris13.fr
Letournel
Murielle
M
Salama
Jeffrey
J
D000270:Adie Syndrome / Q000150:complications* / Q000503:physiopathology; D000532:Altitude Sickness / Q000503:physiopathology*; D002628:Chemoreceptor Cells / Q000502:physiology; D017079:Exercise Tolerance / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011654:Pulmonary Edema / Q000503:physiopathology*