title: Determination of multislice computed tomography dose index (CTDI) using optically stimulated luminescence technology.
abstract: OBJECTIVE
  The extensive use of multislice computed tomography (MSCT) and the associated increase in patient dose calls for an accurate dose evaluation technique. Optically stimulated luminescence (OSL) dosimetry provides a potential solution to the arising concerns over patient dose. This study was intended to evaluate the feasibility and accuracy of OSL dosimeter systems in the diagnostic CT x-ray beam energy range.
  
  
  METHODS
  MSCT dose profiles were measured by irradiating OSL strips placed inside the extended PMMA head and body phantoms at different scan conditions by varying kVp settings (100, 120, and 140 kVp) and collimated beam widths (5, 10, 20, and 40 mm). All scans in this study were performed using a GE Lightspeed VCT scanner in axial mode. The exposed strips were then read out using a custom-made OSL strip reader and corrected with field-specific conversion factors. Based on the corrected OSL dose profile, the CTDI(450-OSL) and CTDI(l00-OSL) were evaluated. CTDI(100-IC) was also obtained using a 100 mm long pencil ionization chamber for accuracy verification. CTDI(100-efficiency) can be further evaluated by calculating the ratio of CTDI(100-OSL) and CTDI(450-OSL), which was compared to results from previous studies as well.
  
  
  RESULTS
  The OSL detectors were found to have good sensitivity and dose response over a wide range of diagnostic CT x-ray beam energy viz. the primary beam and the scatter tail section of the dose profile. The differences between CTDI100 values obtained using the OSL strips and those obtained with 100 mm long pencil ionization chamber were < +/- 5% for all scan conditions, indicating good accuracy of the OSL system. It was also found that the CTDI(100-efficiency) did not significantly change as the beam width increased and tube voltage changed. The average CTDI(100-efficiency) at the center of the head and body phantoms were 72.6% and 56.2%, respectively. The corresponding values for the periphery of the head and body phantoms were 85.0% and 81.7%. These results agreed very well with previous results from the literature using other detection techniques or Monte Carlo simulations.
  
  
  CONCLUSIONS
  The LED-based OSL system can be an accurate alternative device for CT dose evaluations. CTDI100 measurement with the use of a 100 mm pencil ionization chamber substantially underestimates the CTDIinfinity value even with 5 mm collimated beam width. The established complete set of CTDI(100-efficiency) correction factors for various scan parameters allows for accurately estimating CTDIinfinity with the current use of pencil chamber and dose phantoms. Combined with the simple calibration, it gives this work great potential to be used not only in routine clinical quality assurance checks but also as a promising tool for patient organ dose assessment.
authors.affiliation: Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. chun-ruan@ouhsc.edu
authors.forename: Chun
authors.initials: C
authors.lastname: Ruan
authors.forename: Eduardo G
authors.initials: EG
authors.lastname: Yukihara
authors.forename: William J
authors.initials: WJ
authors.lastname: Clouse
authors.forename: Patricia B R
authors.initials: PB
authors.lastname: Gasparian
authors.forename: Salahuddin
authors.initials: S
authors.lastname: Ahmad
mesh_terms: D005240:Feasibility Studies; D006801:Humans; D008163:Luminescent Measurements; D009010:Monte Carlo Method; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed