title: Importance of precentral motor regions in human kinesthesia: a single case study.
abstract: Prompted by our neuroimaging findings in 60 normal people, we examined whether focal damage to the hand section of precentral motor regions impairs hand kinesthesia in a patient, and investigated brain regions related to recovery of kinesthetic function. The damage impaired contralateral kinesthesia. The peri-lesional cerebral motor region, together with the ipsilateral intermediate cerebellum, participated in the recovered kinesthetic processing. The study confirmed the importance of precentral motor regions in human kinesthesia, and indicated a contribution of the peri-lesional cerebral region in recovered kinesthesia after precentral damage, which conceptually fits with cases of recovery of motor function.
authors.affiliation: National Institute of Information and Communication Technology, Research Department 1, Kobe Advanced ICT Research Center, Kyoto, Japan. enaito@atr.jp
authors.forename: Eiichi
authors.initials: E
authors.lastname: Naito
authors.forename: Riki
authors.initials: R
authors.lastname: Matsumoto
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Hagura
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Oouchida
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Tomimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Hanakawa
mesh_terms: D000368:Aged; D001931:Brain Mapping; D002531:Cerebellum / Q000033:anatomy & histology / Q000502:physiology; D006225:Hand; D006801:Humans; D007699:Kinesthesis; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology* / Q000473:pathology / Q000502:physiology*; D009068:Movement; D020127:Recovery of Function