Malignant pheochromocytoma metastasis to the breast shown on I-123 MIBG scan.
A 36-year-old woman was referred to our department for I-123 metaiodobenzylguanidine (MIBG)-SPECT/CT scan 3 years after surgical excision of pheochromocytoma. She was referred due to recurrence of her symptoms as well as raised urinary catecholamines. Review of I-123 MIBG scan revealed multiple MIBG-avid metastatic lesions. Most of these were bony lesions, however, there were also 2 soft tissue lesions in the left breast. She subsequently underwent ultrasound-guided fine-needle aspiration of the left breast lesions. Fine-needle aspiration revealed cytologic changes consistent with pheochromocytoma. There has only been 1 previous reported case of pheochromocytoma metastasizing to the breast. This is the first case in which the metastasis was detected by I-123 MIBG scan.
Patel
Mihir
M
Department of Radiology/Nuclear Medicine, Monash Medical Centre, Southern Health, Clayton, Victoria, Australia. mihirp97@yahoo.co.nz
Santos
Peter
P
Jong
Ian
I
Nandurkar
Dee
D
McKay
John
J
D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000473:pathology*; D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D006801:Humans; D010673:Pheochromocytoma / Q000473:pathology*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D019797:3-Iodobenzylguanidine