title: Survival probability of zirconia-based fixed dental prostheses up to 5 yr: a systematic review of the literature.
abstract: The purpose of this systematic review was to calculate the 5-yr survival rates of all-ceramic zirconia-based fixed dental prostheses (FDPs) and to analyze technical and biological complications. An electronic literature search of MEDLINE (PubMed) was conducted independently by three reviewers to identify clinical studies from 1999 to 2009 and was completed by a manual search. Keywords and inclusion and exclusion criteria were well-defined. The search revealed 399 titles and led to the final analysis of 18 full-text articles. Nine studies met the inclusion criteria. Extracted data were statistically calculated into 5-yr survival rates and 5-yr complication-free rates by using Poisson regression analysis. In total, 310, 3- to 4-unit FDPs and 20 FDPs with more than 4 units were included. The estimated 5-yr survival rate for all FDPs was 94.29% (95% CI: 58.98-99.32); 19 FDPs were lost as a result of catastrophic failures. The 5-yr complication-free rate regarding technical complications was 76.41% (95% CI: 42.42-91.60) with chipping being the most frequent complication. Regarding biological complications, the 5-yr complication-free rate was 91.72% (95% CI: 59.19-98.53). The survival rates of zirconia-based short-unit FDPs are promising. However, an important improvement of the veneering systems is required, and for FDPs with more units in function, further randomized, controlled clinical trials are necessary.
authors.affiliation: Department of Prosthodontics and Dental Materials, Medical Faculty, RWTH Aachen University, Aachen, Germany. jschley@ukaachen.de
authors.forename: Jaana-Sophia
authors.initials: JS
authors.lastname: Schley
authors.forename: Nicole
authors.initials: N
authors.lastname: Heussen
authors.forename: Sven
authors.initials: S
authors.lastname: Reich
authors.forename: Jan
authors.initials: J
authors.lastname: Fischer
authors.forename: Klaus
authors.initials: K
authors.lastname: Haselhuhn
authors.forename: Stefan
authors.initials: S
authors.lastname: Wolfart
mesh_terms: D002484:Cementation; D017076:Computer-Aided Design; D003776:Dental Porcelain; D019232:Dental Restoration Failure; D003779:Denture Design; D003781:Denture Retention; D003830:Denture, Partial, Fixed; D006801:Humans; D016015:Logistic Models; D016019:Survival Analysis; D015040:Zirconium
chemical_list: D003776:Dental Porcelain; D015040:Zirconium; C028541:zirconium oxide