title: Chiral phosphoric acid-catalyzed enantioselective transfer hydrogenation of ortho-hydroxyaryl alkyl N-H ketimines.
abstract: The first enantioselective chiral phosphoric acid-catalyzed transfer hydrogenation of unprotected ortho-hydroxyaryl alkyl N-H ketimines using Hantszch di-tert-butyl ester as a reductant is reported. A variety of ortho-hydroxybenzylamines were obtained in good to excellent yields and enantiomeric excesses.
authors.affiliation: Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Thanh Binh
authors.initials: TB
authors.lastname: Nguyen
authors.forename: Hadjira
authors.initials: H
authors.lastname: Bousserouel
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Françoise
authors.initials: F
authors.lastname: Guéritte