title: [Immunological aspects in glaucoma].
abstract: Glaucoma is one of the most frequent causes of vision loss and blindness. The increased intraocular pressure does not explain glaucoma in all patients but can be considered as a risk factor of the disease. It seems that systemic immunity of the eye through up-and-down immunological regulation of autoantibodies against ocular antigens make their impact felt on glaucoma patients too. The cells from retinal ganglion and aqueous humor itself can be the aperture selection of ocular immune response involved in glaucoma pathogenesis. Among its multiple functions, the immune system confers a protective action on retinal neurons. It is very important the immune maintenance in glaucoma, which involves on the other side the activity of immunoprotection and neuroprotection factors.
authors.forename: B
authors.initials: B
authors.lastname: Istrate
mesh_terms: D001082:Aqueous Humor / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology*; D015415:Biomarkers / Q000378:metabolism; D001766:Blindness / Q000517:prevention & control; D005901:Glaucoma / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D006801:Humans; D018696:Neuroprotective Agents / Q000627:therapeutic use; D012165:Retinal Ganglion Cells / Q000276:immunology; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D018696:Neuroprotective Agents