title: Electroencephalography during out-of-hospital cardiopulmonary resuscitation.
abstract: BACKGROUND
  At the present time there is no parameter that can estimate the quality of cerebral perfusion and possible success of cerebral resuscitation during advanced cardiac life support (ACLS) efforts. In recent years, various attempts have been made to use electroencephalography (EEG)-based cerebral neuromonitoring to assess the effectiveness of cardiopulmonary resuscitation (CPR).
  
  
  OBJECTIVE
  The Cerebral State Monitor M3 (Danmeter A/S, Odense, Denmark) is a portable, single-channel EEG monitor that provides the user with different EEG-based parameters and the raw waveform EEG to measure cerebral activity.
  
  
  METHODS
  We report two cases of out-of-hospital CPR with single-channel EEG monitoring conducted parallel to ACLS with external chest compressions. We demonstrate an artifact in waveform EEG recordings that is caused by the external chest compressions, and that leads to a miscalculation of the Burst Suppression Ratio and Cerebral State Index.
  
  
  CONCLUSIONS
  These cases suggest that digitally processed EEG-monitoring is not a useful tool during CPR.
authors.affiliation: Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Nitzschke
authors.forename: Gunter N
authors.initials: GN
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D022561:Advanced Cardiac Life Support; D000368:Aged; D016477:Artifacts; D054022:Cerebrum / Q000098:blood supply / Q000503:physiopathology*; D056805:Consciousness Monitors; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D058687:Out-of-Hospital Cardiac Arrest / Q000503:physiopathology / Q000628:therapy*