title: Racial disparities in diarrhea-associated hospitalizations among children in five US States, before and after introduction of rotavirus vaccine.
abstract: Racial differences in diarrheal disease have not been systematically examined, and the impact of rotavirus vaccine on these differences has not been assessed. We compared diarrhea-associated hospitalizations by race/ethnicity among children <5 years pre- (2000-2006) and post- (2007 and 2008) rotavirus vaccine introduction in five US states. Pre-vaccine hospitalization rates were greater among whites versus blacks and Hispanics. However, black (versus non-black) infants <6 months and white (versus non-white) children ≥ 1 year had higher rates. In 2008, racial disparities for children 12-35 months resolved, but higher hospitalization rates among black infants <6 months persisted, highlighting the need for timely vaccination.
authors.affiliation: National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. cyen@cdc.gov
authors.forename: Catherine
authors.initials: C
authors.lastname: Yen
authors.forename: Claudia A
authors.initials: CA
authors.lastname: Steiner
authors.forename: Marguerite
authors.initials: M
authors.lastname: Barrett
authors.forename: Aaron T
authors.initials: AT
authors.lastname: Curns
authors.forename: Katherine
authors.initials: K
authors.lastname: Hunter
authors.forename: Emily
authors.initials: E
authors.lastname: Wilson
authors.forename: Umesh D
authors.initials: UD
authors.lastname: Parashar
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D002675:Child, Preschool; D003967:Diarrhea / Q000517:prevention & control* / Q000821:virology; D054624:Health Status Disparities; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D012400:Rotavirus Infections / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage*; D014481:United States; D014611:Vaccination / Q000706:statistics & numerical data; D044465:White People / Q000706:statistics & numerical data
chemical_list: D022243:Rotavirus Vaccines