title: Birth defects after assisted reproductive technologies in China: analysis of 15,405 offspring in seven centers (2004 to 2008).
abstract: This first large-scale report of birth defects in 15,405 offspring conceived by assisted reproductive technologies in China found infants born after IVF alone to have a birth defect frequency comparable to that in the general Chinese population; rates were nonsignificantly higher in infants conceived with use of intracytoplasmic sperm injection compared with those conceived after IVF alone.
authors.affiliation: Center for Reproductive Medicine, Shandong University, Jinan, People's Republic of China.
authors.forename: Junhao
authors.initials: J
authors.lastname: Yan
authors.forename: Guoning
authors.initials: G
authors.lastname: Huang
authors.forename: Yingpu
authors.initials: Y
authors.lastname: Sun
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zhao
authors.forename: Shiling
authors.initials: S
authors.lastname: Chen
authors.forename: Shuhua
authors.initials: S
authors.lastname: Zou
authors.forename: Cuifang
authors.initials: C
authors.lastname: Hao
authors.forename: Song
authors.initials: S
authors.lastname: Quan
authors.forename: Zi-Jiang
authors.initials: ZJ
authors.lastname: Chen
mesh_terms: D002681:China / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007317:Insemination, Artificial, Homologous / Q000009:adverse effects / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects* / Q000706:statistics & numerical data*; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects / Q000706:statistics & numerical data