title: Randomized clinical trials for new surgical operations: square peg in a round hole?
authors.affiliation: Hospital of the University of Pennsylvania, Division of Thoracic Surgery, Philadelphia, PA 19104, USA. joel.cooper@uphs.upenn.edu
authors.forename: Joel D
authors.initials: JD
authors.lastname: Cooper
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D018570:Risk Assessment; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D016896:Treatment Outcome