title: An analysis tool to calculate permeability based on the Patlak method.
abstract: Strokes are commonly diagnosed by utilizing images obtained from magnetic resonance imaging (MRI) technology. Nowadays, computer software can play a large role in analyzing these images and arriving at diagnoses quickly and accurately. Additionally, this software can reduce workload for medical personnel and lower misdiagnoses. In this paper a flexible permeability calculation tool called PCT based on the Patlak plot method is presented. Using the PCT we can calculate the permeability co-efficient of the Blood-Brain Barrier (BBB) function. The PCT tool offers both manual and automatic options for diagnosing the regions of the brain affected by stroke. Moreover, the PCT tool supports various extensions such as dicom, nifty and analyze.
authors.affiliation: Sakarya University, Sakarya, Turkey. ocetin@sakarya.edu.tr
authors.forename: Ozdemir
authors.initials: O
authors.lastname: Cetin
mesh_terms: D001812:Blood-Brain Barrier; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging; D010539:Permeability; D012984:Software; D020521:Stroke / Q000175:diagnosis / Q000378:metabolism*; D014584:User-Computer Interface