Idiopathic orbital inflammation leading to unilateral blindness over a 2-day presentation in a child.
An 8-year-old boy developed vision loss to no light perception on the left side over a 2-day period. He initially presented with unilateral eyelid swelling, which progressed to bilateral edema and an eventual left-sided orbital apex syndrome. Orbital imaging revealed enlarged extraocular muscles, and biopsy confirmed idiopathic orbital inflammation. Despite subsequent orbital decompression, high-dose steroids, and additional steroid-sparing therapy, he did not regain vision after 9 months of follow up.
Eftekhari
Kian
K
Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Chikwava
Kudakwashe R
KR
Katowitz
William R
WR
D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D001766:Blindness / Q000209:etiology*; D002648:Child; D004359:Drug Therapy, Combination; D004487:Edema / Q000209:etiology; D005141:Eyelid Diseases / Q000209:etiology; D006801:Humans; D000069285:Infliximab; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009801:Oculomotor Muscles / Q000473:pathology; D016727:Orbital Pseudotumor / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity
D000911:Antibodies, Monoclonal; D000069285:Infliximab; D008727:Methotrexate