title: Screening of the constituents, antimicrobial and antioxidant activity of endemic Origanum hypericifolium O. Schwartz & P.H. Davis.
abstract: The chemical compositions, total phenol content, antioxidant and antimicrobial activities with oxidant status of the essential oil from an endemic Turkish species, Origanum hypericifolium, were investigated. Steam distillation (SD) was used to isolate the essential oils, and the chemical analyses were performed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity was tested by agar disc diffusion method against Morganella morganii (clinic isolate), Micrococcus flavus (clinic isolate), Micrococcus luteus NRLL B-4375, Proteus vulgaris RSKK 96026, Escherichia coli ATCC 11230, Escherichia coli ATCC 25922, Yersinia enterecolitica RSKK 1501, Staphylococcus aureus ATCC 25923, S. aureus ATCC 25933, S. aureus ATCC 12598, S. aureus (clinic isolate), MRSA 1 (clinic isolate), MRSA 2 (clinic isolate), MRSA 3 (clinic isolate) and MRSA 4 (clinic isolate). The major compounds found in volatiles of O. hypericifolium were p-cymene, carvacrol and γ-terpinene. Results showed that O. hypericifolium has the potential for being used in food and medicine because of its antioxidant and antibacterial activity.
authors.affiliation: Department of Biology, Faculty of Arts and Science, Pamukkale University, Denizli, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Celik
authors.forename: E
authors.initials: E
authors.lastname: Nur Herken
authors.forename: Idris
authors.initials: I
authors.lastname: Arslan
authors.forename: M
authors.initials: M
authors.lastname: Zafer Ozel
authors.forename: Nazime
authors.initials: N
authors.lastname: Mercan
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D000975:Antioxidants / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry*; D031341:Origanum / Q000737:chemistry*; D010636:Phenols / Q000032:analysis
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D009822:Oils, Volatile; D010636:Phenols