Nephrogenic systemic fibrosis.
Nephroaenic systemic fibrosis (NSF) is a potentiallv fatal dermatiological condition found exclusively in patients with advanced renal I failure. There is minimal literature regarding the epidemiology and outcomes of patients with NSF in Ireland. A retrospective chart review was performed for all patients with NSF in Ireland. Ireland's experience with the disease was examined in light of international reports. There have been three cases of NSF in Ireland; an area which serves 1915 dialysis patients--giving a point prevalence among Irish end-stage kidney disease patients of 0.002. There was a large variation in disease severity between the three patients. All three patients had significant exposure to gadolinium chelate. Caution with gadolinium administration must be exercised in patients with advanced renal failure.
Kennedy
C
C
Department of Nephrology, Beaumont Hospital, Beaumont, Dublin 9. kennedyclaire@gmail.com
Magee
C
C
Eltayeb
E
E
Gulmann
C
C
Conlon
P J
PJ
D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000009:adverse effects; D005260:Female; D019786:Gadolinium DTPA / Q000009:adverse effects; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D054989:Nephrogenic Fibrosing Dermopathy / Q000175:diagnosis* / Q000453:epidemiology; D010530:Peritoneal Dialysis
D003287:Contrast Media; D019786:Gadolinium DTPA