title: Identification of relations between risk factors and their pathologies or health conditions by mining scientific literature.
abstract: Risk factors discovery and prevention is an active research field within the biomedical domain. Despite abundant existing information on risk factors, as found in bibliographical databases or on several websites, accessing this information may be difficult. Methods from Natural Language Processing and Information Extraction can be helpful to access it more easily. Specifically, we show a procedure for analyzing massive amounts of scientific literature and for detecting linguistically marked associations between pathologies and risk factors. This approach allowed us to extract over 22,000 risk factors and associated pathologies. The performed evaluations pointed out that (1) over 88% of risk factors for coronary heart disease are correct, (2) associated pathologies, when they could be compared to MeSH indexing, are correct in about 70%, and (3) in existing terminologies links between risk factors and their pathologies are seldom recorded.
authors.affiliation: UFR SMBH Léonard de Vinci, Université Paris 13, 93017 Bobigny France. thierry.hamon@univ-paris13.fr
authors.forename: Thierry
authors.initials: T
authors.lastname: Hamon
authors.forename: Martin
authors.initials: M
authors.lastname: Graña
authors.forename: Víctor
authors.initials: V
authors.lastname: Raggio
authors.forename: Natalia
authors.initials: N
authors.lastname: Grabar
authors.forename: Hugo
authors.initials: H
authors.lastname: Naya
mesh_terms: D000043:Abstracting and Indexing / Q000379:methods; D057225:Data Mining / Q000592:standards*; D016206:Databases, Bibliographic; D004194:Disease; D046650:Medical Subject Headings; D009323:Natural Language Processing; D012307:Risk Factors; D012660:Semantics; D014481:United States