Bis-exo-2-norbornylboron triflate for stereospecific enolization of 3,3,3-trifluoropropionates.
The first boron-mediated enolization-aldolization of 3,3,3-trifluoropropionates has been reported. The preparation and application of bis-exo-bicyclo[2.2.1]heptan-2-ylboron triflate as a superior reagent for diastereospecific enolization has also been described.
Ramachandran
P Veeraraghavan
PV
Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907-2084, USA. chandran@purdue.edu
Parthasarathy
Gowrisankar
G
Gagare
Pravin D
PD
D017611:Fluorine Compounds / Q000138:chemical synthesis*; D008750:Methyldopa / Q000737:chemistry; D015394:Molecular Structure; D009636:Norbornanes / Q000138:chemical synthesis*; D011422:Propionates / Q000138:chemical synthesis*; D013237:Stereoisomerism
D017611:Fluorine Compounds; D009636:Norbornanes; D011422:Propionates; C046060:2-norbornene; D008750:Methyldopa