Ruthenium-catalyzed tandem ring-opening/ring-closing/cross-metathesis of 1,6-cyclopropene-ynes and olefins for the construction of the 3-pyrroline skeleton.
Catalyzed by the first-generation Grubbs' ruthenium complex, tandem intramolecular/intermolecular metathesis of 1,6-enynes bearing a cyclopropene ring took place smoothly to produce 3-pyrroline derivatives in satisfactory yields via ring-opening/ring-closing/cross-metathesis processes.
Zhu
Zhi-Bin
ZB
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.
Shi
Min
M