Knowledge and adherence to antiretroviral therapy among adult people living with HIV/AIDS treated in the health care centers of the association "Espoir Vie Togo" in Togo, West Africa.
BACKGROUND
The efficiency of antiretroviral therapy (ART) depends on a near perfect level of patients' adherence. The level of adherence of adults HIV-infected patients treated in the HIV/AIDS health care centres of the association "Espoir Vie Togo" in Togo, West Africa is not properly documented. The aim of the present study was to examine by means of self-reports the knowledge, the adherence level and associated factors to antiretroviral therapy (ART) among these patients.


METHODS
We conducted a cross-sectional survey among adult people living with HIV/AIDS (PLWHA) through a structured questionnaire.


RESULTS
A total of 99 patients were enrolled. Among them, 55.6% knew the name of antiretroviral agents of regimens prescribed. All patients had a good knowledge of treatment schedule. The treatment regimens based on 2 NRTIs + 1 NNRTI were used in 90% of patients. The average adherence rate was 89.8% of the total doses prescribed while 62.62% of patients showed an adherence rate of 95% or above. The treated groups were similar in term of median % of medication doses taken according to PLWHA epidemiological characteristics. However, patients reported forgetting (34.9%), travel (25.6%), cost of treatment (13.9%) and side effects (11.6%) as the main factors of missing at least once a dose intake.


CONCLUSIONS
These results should encourage the association and all the involved actors in the HIV/AIDS's program to strengthen counseling, education and information interventions for HIV-infected patients in order to overcome the potential barriers of poor adherence.
Potchoo
Yao
Y
Faculté Mixte de Médecine et de Pharmacie, Université de Lomé, BP 1515 Lomé, Togo. ypotchoo@hotmail.com
Tchamdja
Kpatcha
K
Balogou
Agnon
A
Pitche
Vincent P
VP
Guissou
Innocent P
IP
Kassang
Etienne K
EK
D000328:Adult; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D032882:Comprehension; D003430:Cross-Sectional Studies; D004334:Drug Administration Schedule; D016527:Drug Costs; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D019538:Health Care Surveys; D007722:Health Knowledge, Attitudes, Practice; D006297:Health Services Accessibility; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D015397:Program Evaluation; D018570:Risk Assessment; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014037:Togo; D014195:Travel; D019037:Urban Health Services; D055815:Young Adult
D044966:Anti-Retroviral Agents