title: Reiterative membranous proliferation with giant-cell deposits on hydrophobic acrylic intraocular lenses after triple procedures in eyes with cataracts and uveitis.
abstract: OBJECTIVE
  To report 2 cases of reiterative membranous proliferation with giant-cell deposits on hydrophobic acrylic intraocular lenses (IOLs) after a triple procedure of vitrectomy, phacoemulsification, and IOL implantation in uveitic eyes with cataracts and vitreous opacity.
  
  
  METHODS
  A 72-year-old Japanese woman and a 67-year-old Japanese man underwent AcrySof IOL (SA60AT) implantation in their eyes (both eyes in the first case and the left eye in the second case) for the treatment of cataract and vitreous opacity with uveitis. Although intraocular inflammation seemed to be successfully controlled, the number of giant-cell deposits on the posterior surface of the posterior capsule was gradually increased with the development of posterior capsular opacification in 5 and 9 months, respectively, and neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy was required.
  
  
  RESULTS
  After the treatment, Nd:YAG laser membranotomy (4 and 5 times) was required because of repeated membranous proliferation with giant-cell deposits occurring on the posterior surface of the IOL monthly, although postoperative intraocular inflammation seemed to be controlled.
  
  
  CONCLUSIONS
  The possibility of development of this undesirable complication, which is believed to be limited in cases with hydrophobic acrylic IOL implantation, should be kept in mind. Also, Nd:YAG laser membranotomy for the proliferative membrane is an available option for recovery of vision.
authors.affiliation: Department of Ophthalmology, Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287-9277, USA.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Iwase
authors.forename: Nobushige
authors.initials: N
authors.lastname: Tanaka
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D002386:Cataract / Q000150:complications / Q000628:therapy; D049109:Cell Proliferation; D005260:Female; D015726:Giant Cells / Q000473:pathology*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D053685:Laser Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000473:pathology*; D011183:Postoperative Complications; D014605:Uveitis / Q000150:complications / Q000601:surgery; D014821:Vitrectomy
chemical_list: D000180:Acrylic Resins