title: The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis.
abstract: The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endometriosis. Afamin levels were altered significantly in the peritoneal fluid of women with endometriosis compared with disease-free controls, correlated with vitamin E levels, and are consistent with increased oxidative stress in the peritoneal cavity of women with endometriosis.
authors.affiliation: Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Innsbruck, Innsbruck, Austria. beata.seeber@uki.at
authors.forename: Beata E
authors.initials: BE
authors.lastname: Seeber
authors.forename: Theresa
authors.initials: T
authors.lastname: Czech
authors.forename: Hannes
authors.initials: H
authors.lastname: Buchner
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Barnhart
authors.forename: Christoph
authors.initials: C
authors.lastname: Seger
authors.forename: Guenter
authors.initials: G
authors.lastname: Daxenbichler
authors.forename: Ludwig
authors.initials: L
authors.lastname: Wildt
authors.forename: Hans
authors.initials: H
authors.lastname: Dieplinger
mesh_terms: D000293:Adolescent; D000328:Adult; D001202:Ascitic Fluid / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology; D002352:Carrier Proteins / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D016022:Case-Control Studies; D004715:Endometriosis / Q000097:blood / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006023:Glycoproteins / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D009994:Osmolar Concentration; D018384:Oxidative Stress / Q000502:physiology; D010532:Peritoneal Diseases / Q000097:blood / Q000378:metabolism* / Q000473:pathology; D012709:Serum Albumin / Q000032:analysis / Q000378:metabolism*; D000075462:Serum Albumin, Human; D014810:Vitamin E / Q000097:blood / Q000378:metabolism; D055815:Young Adult
chemical_list: C088246:AFM protein, human; D002352:Carrier Proteins; D006023:Glycoproteins; D012709:Serum Albumin; D014810:Vitamin E; D000075462:Serum Albumin, Human