[Virological characteristics of pandemic (H1N1) 2009 influenza virus].
In the spring of 2009, a novel swine-origin H1N1 virus, whose antigenicity is quite different from those of seasonal human H1N1 strains, emerged in Mexico and readily transmitted and spread among humans, resulting in the first influenza pandemic in the 21st century. This novel H1N1 virus was shown to be a triple reassortant comprising genes derived from avian, human, and swine viruses. Here, we review our current knowledge of this pandemic influenza virus and discuss future aspects of the pandemic.
Horimoto
Taisuke
T
Division of Virology, Institute of Medical Science, University of Tokyo. horimoto@ims.u-tokyo.ac.jp
Yamada
Shinya
S
Kawaoka
Yoshihiro
Y
D000818:Animals; D004196:Disease Outbreaks; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D008168:Lung / Q000821:virology; D013997:Time Factors; D014764:Viral Proteins; D053585:Virus Attachment
C543345:H1N1 virus hemagglutinin; D019267:Hemagglutinin Glycoproteins, Influenza Virus; C502893:PB2 protein, influenza virus; D014764:Viral Proteins