title: Changing epidemiology of methicillin-resistant Staphylococcus aureus in Alberta, Canada: population-based surveillance, 2005-2008.
abstract: SUMMARYIncreasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) has been reported in Canada. We report the results of a prospective surveillance of MRSA infections in Alberta over a consecutive 3-year period. A total of 8910 unique clinical MRSA isolates was analysed from July 2005 to June 2008. The incidence of MRSA infection increased over the study period and was highest in males, age group ⩾85 years, and the Calgary Area. CMRSA10 (USA300) and CMRSA2 (USA100/800) were the most common PFGE strain types, representing 53·0% and 27·9% of all isolates, respectively. Significant differences were noted between MRSA strains in the source of infection and antimicrobial susceptibility. The incidence of MRSA infection in Alberta has nearly doubled in the last 3 years; this is attributed to the emergence of CMRSA10 as the predominant strain.
authors.affiliation: Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Kim
authors.affiliation: Alberta Provincial Laboratory for Public Health, Alberta Health Services, Alberta, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Ferrato
authors.affiliation: Antimicrobial Resistance and Nosocomial Infections, National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
authors.forename: G R
authors.initials: GR
authors.lastname: Golding
authors.affiliation: Antimicrobial Resistance and Nosocomial Infections, National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
authors.forename: M R
authors.initials: MR
authors.lastname: Mulvey
authors.affiliation: Surveillance and Assessment, Alberta Health and Wellness, Edmonton, Alberta, Canada.
authors.forename: K A
authors.initials: KA
authors.lastname: Simmonds
authors.affiliation: Surveillance and Assessment, Alberta Health and Wellness, Edmonton, Alberta, Canada.
authors.forename: L W
authors.initials: LW
authors.lastname: Svenson
authors.affiliation: Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: G
authors.initials: G
authors.lastname: Keays
authors.affiliation: Alberta Provincial Laboratory for Public Health, Alberta Health Services, Alberta, Canada.
authors.forename: L
authors.initials: L
authors.lastname: Chui
authors.affiliation: Alberta Provincial Laboratory for Public Health, Alberta Health Services, Alberta, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Lovgren
authors.affiliation: Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Louie
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000416:Alberta / Q000453:epidemiology; D015373:Bacterial Typing Techniques; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012737:Sex Factors; D013203:Staphylococcal Infections / Q000453:epidemiology*; D055815:Young Adult