Palladium-catalyzed propargylic substitution with phosphorus nucleophiles: efficient, stereoselective synthesis of allenylphosphonates and related compounds.
A new, efficient method is developed, based on a palladium(0)-catalyzed reaction of propargylic derivatives with various phosphorus nucleophiles, to produce allenylphosphonates and their analogues with defined stereochemistry in the allenic and the phosphonate moiety.
Kalek
Marcin
M
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden.
Johansson
Tommy
T
Jezowska
Martina
M
Stawinski
Jacek
J
D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010710:Phosphates / Q000138:chemical synthesis*; D010758:Phosphorus / Q000737:chemistry*; D013237:Stereoisomerism
D000466:Alkadienes; D010710:Phosphates; D010758:Phosphorus; C025947:propadiene; D010165:Palladium