title: Iridociliary melanoma with secondary lens luxation: distinctive findings in a long-horned cowfish (Lactoria cornuta).
abstract: This report describes a long-horned cowfish, which was diagnosed with buphthalmia and lens sub-luxation in the right eye, conditions that progressed to complete anterior lens luxation and secondary keratoconus. Three months after the initial evaluation, a pigmented mass was observed protruding from the vitreous. An enucleation was performed under general anesthesia. Ocular histopathology revealed an iridociliary melanoma. Reports of intraocular melanomas are extremely rare in fish. To the authors' knowledge, this is the first report of an iridociliary melanoma that led to buphthalmia, lens luxation, and keratoconus in a fish. Histological findings of lens luxation are also demonstrated. Due to the presence of a complex suspensory apparatus involving the teleost lens, this report speculates that lens luxation is a more devastating disease process in teleosts than in mammals.
authors.affiliation: Department of Clinical Sciences, Colorado State University, College of Veterinary Medicine, Fort Collins, Colorado 80523, USA. enrygarcia@hotmail.com
authors.forename: Enry Garcia
authors.initials: EG
authors.lastname: da Silva
authors.forename: Juliet R
authors.initials: JR
authors.lastname: Gionfriddo
authors.forename: Cynthia C
authors.initials: CC
authors.lastname: Powell
authors.forename: Terry W
authors.initials: TW
authors.lastname: Campbell
authors.forename: E J
authors.initials: EJ
authors.lastname: Ehrhart
mesh_terms: D000818:Animals; D005134:Eye Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D005393:Fish Diseases / Q000473:pathology* / Q000601:surgery; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D023721:Tetraodontiformes