Vaccines to antibodies: grow up!
Through a process called affinity maturation, all of the HIV-specific antibodies identified so far have accumulated multiple mutations, some of which are required for them to bind to and neutralize HIV. Researchers are now beginning to grapple with what this means for vaccine design.
von Bubnoff
Andreas
A
D016915:AIDS Vaccines / Q000276:immunology*; D057134:Antibodies, Neutralizing / Q000276:immunology; D000915:Antibody Affinity; D015483:HIV Antibodies / Q000276:immunology*; D006801:Humans
D016915:AIDS Vaccines; D057134:Antibodies, Neutralizing; D015483:HIV Antibodies