title: Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine.
abstract: We propose herein an alternative biosynthetic pathway for palau'amine in order to resolve the stereochemical issue from the original Kinnel-Scheuer hypothesis. Furthermore, we use this revised hypothesis as a guide toward the laboratory synthesis of palau'amine.
authors.affiliation: Department of Biochemistry, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9038, USA.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Ma
authors.forename: Jianming
authors.initials: J
authors.lastname: Lu
authors.forename: Xiao
authors.initials: X
authors.lastname: Wang
authors.forename: Chuo
authors.initials: C
authors.lastname: Chen
mesh_terms: D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000096:biosynthesis / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D010456:Peptides, Cyclic; C482752:palauamide