When is standard treatment sufficiently active to make use of a placebo-controlled trial unethical?
Research has demonstrated that double blinding can lessen the potential for bias in study outcomes, such as perceiving a drug as more effective in the experimental arm of a study. Effective double-blinding techniques minimize the influence of investigator and patient expectations.
Grünwald
Hans W
HW
Storm
Courtney D
CD
Jacobson
Geraldine M
GM