Unexpected primary osseous lymphoma as the cause of lactic acidosis in a patient suffering from pancreatitis.
A 45-year-old man was admitted due to acute pancreatitis. A severe lactic acidosis was found. Following active therapy, the signs and symptoms from pancreatitis was improved, but acidosis was exacerbated. FDG PET/CT images were acquired to investigate the etiology of lactic acidosis and/or other unknown pathology. The images showed widespread abnormal FDG activity in the bone marrows throughout the body, suggestive of hematologic malignancy, which was confirmed as primary osseous non-Hodgkin lymphoma following a histopathological examination of the bone marrow. Chemotherapy against lymphoma was initiated and status of the lactic acidosis was rapidly corrected.
Huo
Li
L
Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, People's Republic of China.
Luo
Yaping
Y
Zhang
Taiping
T
Zhu
Zhaohui
Z
Li
Fang
F
Zhao
Yupei
Y
D000140:Acidosis, Lactic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18