[Effectiveness of traditional Chinese medicine and Western medicine in treating residual deep burn wound].
OBJECTIVE
To compare the effectiveness of dressing by a combination of traditional Chinese medicine (TCM)-Western medicine (WM) after TCM bath and by the silver sulfadiazine cream (SD-Ag) in treating residual deep burn wound.


METHODS
A total of 128 cases of residual deep burn wound between July 2003 and December 2009 were randomly divided into the TCM-WM treatment group (70 cases) and the WM control group (58 cases). In the treatment group, there were 45 males and 25 females with an average age of 38.6 years (range, 18-60 years), including 34 cases of flame burns, 28 cases of molten steel burns, and 8 cases of chemical burns with an average burn area of 57.6% total body surface area (TBSA) and an average residual wound of 7.4% TBSA. In the control group, there were 50 males and 8 females with an average of 37.9 years (range, 20-59 years), including 26 cases of flame burns, 12 cases of hot water burns, 16 cases of molten steel burns, and 4 cases of chemical burns with an average burn area of 56.5% TBSA and an average residual wound of 6.9% TBSA. There was no significant difference in general data between 2 groups (P > 0.05), so the clinical data of 2 groups had comparability. In the treatment group, the patients had a bath with TCM, and then the wounds were treated with dressing change of combined TCM-WM. In the control group, the wounds were treated with SD-Ag after cleaning the wounds with chlorhexidine solution. The pain, wound healing time, and the rate of scar formation were observed in 2 groups after treatment.


RESULTS
According to wound pain classification after medication, the results were excellent in 23 cases, good in 30 cases, fair in 17 cases in the treatment group; were excellent in 17 cases, good in 20 cases, fair in 13 cases, poor in 5 cases, and fairly poor in 3 cases in the control group. The wound healing time of the treatment group (13.45 +/- 4.74) days was significantly shorter than that of the control group [(23.87 +/- 14.45) days, P < 0.05)]. After 2 weeks of treatment, scar occurred in 15 patients (21.4%) of the treatment group and 35 patients (60.3%) of the control group, showing significant difference (P < 0.05).


CONCLUSIONS
Based on TCM bath, a combination of TCM-WM for the residual burn wounds is obviously superior to SD-Ag. It has the advantages of rapid healing, light pain, no obvious scar, and short hospitalization time.
Lv
Guozhong
G
Department of Burn and Plastic Surgery, Third Affiliated Hospital of Nantong University, Wuxi Jiangsu 214041, PR China.
Cai
Liangliang
L
Yu
Junjie
J
D000293:Adolescent; D000328:Adult; D001452:Balneology; D002056:Burns / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing; D055815:Young Adult
D012837:Silver Sulfadiazine