Malignant insulinoma in a child.
Insulinomas are rare tumors with an estimated incidence of one per 250,000 person-years. Most insulinomas are benign with less than 10% demonstrating malignant behavior, the vast majority of which occur in adults. A systemic review of the literature revealed only nine cases of malignant insulinomas occurring in children. Herein, we present a case of metastatic malignant insulinoma in a 12-year-old child. The occurrence of this diagnosis in a child, its unusual pattern of metastases and the challenging management of severe hypoglycemia make this case worth reporting.
Janem
Waleed
W
Department of Pediatric Oncology, King Hussein Cancer Center, Amman, Jordan.
Sultan
Iyad
I
Ajlouni
Fatena
F
Deebajeh
Rasha
R
Haddad
Hussam
H
Sughayer
Maher A
MA
Goussous
Rula Y
RY
D002648:Child; D006801:Humans; D007340:Insulinoma / Q000175:diagnosis* / Q000556:secondary; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology