title: Subconjunctival masses associated with central nervous system rosai-dorfman disease.
abstract: OBJECTIVE
  To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease.
  
  
  CONCLUSIONS
  The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. kcavuoto@med.miami.edu
authors.forename: Kara
authors.initials: K
authors.lastname: Cavuoto
authors.forename: Anat
authors.initials: A
authors.lastname: Galor
authors.forename: Sander R
authors.initials: SR
authors.lastname: Dubovy
authors.forename: Ninel
authors.initials: N
authors.lastname: Gregori
authors.forename: Micheline
authors.initials: M
authors.lastname: McCarthy
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003229:Conjunctival Diseases / Q000473:pathology* / Q000601:surgery; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology; D013256:Steroids / Q000008:administration & dosage
chemical_list: D013256:Steroids