title: Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations.
abstract: A total of 149 unrelated and healthy individuals comprising: Tunisian Berbers, Tunisians with Andalusian origin and Libyans were typed with the SNPforID 34-plex ancestry informative marker (AIM) SNP panel. Results of 31 of the 34 SNPs are presented and no deviations from Hardy-Weinberg equilibrium were observed after Bonferroni correction (p=0.00161) except rs722098 (p=0.0000). Comparisons of allele frequencies showed high divergence values between North Africans and Europeans (δ>30%) in markers: rs4540055 (allele A) and rs16891982. Our study adds data that can be used as training set genotypes for future ancestry investigations in forensic cases and suggests these AIM-SNPs can successfully differentiate North Africans and Mediterranean Europeans.
authors.affiliation: Laboratory of Genetics, Immunology and Human Pathology, Faculty of Sciences of Tunis, El Manar University, Manar I, 1060 Tunis, Tunisia. housseinkek@yahoo.fr
authors.forename: H
authors.initials: H
authors.lastname: Khodjet-el-Khil
authors.forename: K
authors.initials: K
authors.lastname: Fadhlaoui-Zid
authors.forename: L
authors.initials: L
authors.lastname: Cherni
authors.forename: C
authors.initials: C
authors.lastname: Phillips
authors.forename: M
authors.initials: M
authors.lastname: Fondevila
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
authors.forename: A
authors.initials: A
authors.lastname: Ben Ammar-Elgaaied
mesh_terms: D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008002:Libya; D020641:Polymorphism, Single Nucleotide; D014416:Tunisia