title: A familial spontaneous epileptic feline strain: a novel model of idiopathic/genetic epilepsy.
abstract: A spontaneous epileptic model of cats has not been described previously. Recently, we identified familial epileptic cats and investigated their clinical features. These epileptic cats are healthy except for the presence of recurrent seizures that are typically a focal limbic seizure with secondary generalization. Furthermore, generalized seizures were induced by vestibular stimulation in some cats. This spontaneous epileptic cat strain may be a valuable model for idiopathic/genetic epilepsy.
authors.affiliation: Division of Veterinary Radiology, Department of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyounancho, Musashinoshi, Tokyo 180-8602, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kuwabara
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hasegawa
authors.forename: Fukie
authors.initials: F
authors.lastname: Ogawa
authors.forename: Masanori
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Michio
authors.initials: M
authors.lastname: Fujita
authors.forename: Hiroetsu
authors.initials: H
authors.lastname: Suzuki
authors.forename: Naoaki
authors.initials: N
authors.lastname: Matsuki
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Orima
mesh_terms: D000818:Animals; D002415:Cats; D004195:Disease Models, Animal; D004569:Electroencephalography / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis / Q000235:genetics* / Q000662:veterinary*; D007178:Inbreeding / Q000379:methods; D010375:Pedigree; D010406:Penicillins
chemical_list: D010406:Penicillins