Lack of the cerebral peduncle involvement in a series of adult supratentorial AVM: a diffusion tensor imaging study.
Congenital as arteriovenous malformation(AVM) is, most patients with AVM would be asymptomatic until adults. During the past 2 years, 23 cases of adult supratentorial AVM patients had DTI after admission. The region of interest was placed in the cerebral peduncle. Their FA value and fiber number was compared with those of cavernous malformation (CM) and tumor (glioma and meningioma). In the AVM group, there was no significant difference in FA of the cerebral peduncle (ipsilateral 0.758±0.055 versus contralateral 0.755±0.049; P>0.05) and fiber number (319.6±82.9 versus 304.7±89.1; P>0.05). In the CM group, FA of the cerebral peduncle on ipsilateral side (0.711±0.092) was significantly lower than that of contralateral side (0.768±0.043) (P<0.01). Similar result was in fiber number of the CM group (251±82.1 versus 307.3±77.0; P<0.05). In tumor group, FA of ipsilateral side (0.713±0.084) was lower than that of contralateral (0.751±0.052) without significant difference. There was no significant difference in fiber number between ipsilateral and contralateral sides in the tumor group (308.9±112.4 versus 287.9±62.4). Unlike non-AVM lesions (CM and tumor), FA value and fiber number of the ipsilateral cerebral peduncle is less influenced in the AVM group. The lack of the cerebral peduncle involvement indicates that there is plasticity of white matter in AVM.
Fu
Bing
B
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Zhao
Jizong
J
Wang
Bo
B
Yang
Mingqi
M
Xu
Long
L
Zhuo
Yan
Y
D000328:Adult; D001165:Arteriovenous Malformations / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology; D056324:Diffusion Tensor Imaging / Q000379:methods; D004525:Efferent Pathways / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D009416:Nerve Regeneration / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology; D011712:Pyramidal Tracts / Q000473:pathology / Q000503:physiopathology; D013681:Tegmentum Mesencephali / Q000473:pathology* / Q000503:physiopathology; D055815:Young Adult