title: [The clinical significance of ABR testing in the diagnosis of the large vestibular aqueduct syndrome].
abstract: OBJECTIVE
  To analyse the clinical audiological significance in the diagnosis of large vestibular aqueduct syndrome (LVAS) by the auditory brain stem response (ABR) testing.
  
  
  METHODS
  Patients with sensorineural hearing loss were examined by temporal bone CT scanning from January, 2008 to September, 2009. The result of CT scanning of 70 cases inner ear malformation were analysed. Patients were divided into two groups, LVAS group including 38 cases (76 ears) and other inner ear malformation group including 32 cases (62 ears). All patient accepted clinical audiology analysis and auditory brainstem response (ABR) test.
  
  
  RESULTS
  Twenty-four cases (41 ears) of LVAS group were detected with ASNR in 2 3 cm by the ABR testing, the positive rate was 54%, while ASNR was not detected in patients of other inner ear malformations group. There was significant differences (P=0.01) of the ASNR between two groups.
  
  
  CONCLUSIONS
  There is high incidence of LVAS on the patients with non-syndromic deafness. ASNR by ABR testing could help diagnosing the LVAS.
authors.affiliation: Department of Otorhinolaryngology, Rehabilitation Center Hospital of Gansu Province, Lanzhou, China. kfyyhjp@sina.com
authors.forename: Jianping
authors.initials: J
authors.lastname: Hao
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Wenfei
authors.initials: W
authors.lastname: Yan
authors.forename: Tianxiang
authors.initials: T
authors.lastname: Shi
mesh_terms: D002648:Child; D002675:Child, Preschool; D007758:Ear, Inner / Q000002:abnormalities*; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013577:Syndrome; D014723:Vestibular Aqueduct / Q000002:abnormalities*