title: [The primary disorder of sphincter relaxation or Fowler's syndrome].
abstract: The primary disorder of sphincter relaxation or Fowler's syndrome constitutes the first cause of urinary retention in young women after ruling neurological, iatrogenic and local origins out. It includes painless urinary retention, polycystic ovaries in more than 50% of the cases, high maximum urethral closure pressure, increase in sphincter volume and striated urethral sphincter electromyography abnormalities. So far, the only treatment restoring micturation in this condition is sacral neuromodulation.
authors.affiliation: Department of Uro-Neurology, UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, Royaume-Uni. gamexavier@gmail.com
authors.forename: X
authors.initials: X
authors.lastname: Gamé
authors.forename: C-J
authors.initials: CJ
authors.lastname: Fowler
mesh_terms: D005260:Female; D006801:Humans; D009126:Muscle Relaxation; D013577:Syndrome; D014515:Ureteral Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016055:Urinary Retention / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy