title: HIV-1 RNA detection in the amniotic fluid of HIV-infected pregnant women.
abstract: This study is aimed at evaluating the potential to detect human immunodeficiency virus (HIV) in amniotic fluid (AF) collected at delivery from 40 HIV-positive pregnant women. Thirty patients had a plasma viral load (VL) below 1,000 copies/mL at delivery. VL was positive in three AF samples. No significant association was found between the HIV-1 RNA in AF and the maternal plasma samples. There was no HIV vertical transmission detected.
authors.affiliation: Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
authors.forename: Ana Christina
authors.initials: AC
authors.lastname: Lobato
authors.forename: Regina Amélia
authors.initials: RA
authors.lastname: Aguiar
authors.forename: Agdemir Waléria
authors.initials: AW
authors.lastname: Aleixo
authors.forename: Beatriz Amélia
authors.initials: BA
authors.lastname: Andrade
authors.forename: Ines Katherina
authors.initials: IK
authors.lastname: Cavallo
authors.forename: Fabiana Maria
authors.initials: FM
authors.lastname: Kakehasi
authors.forename: Jorge Andrade
authors.initials: JA
authors.lastname: Pinto
authors.forename: Victor Hugo
authors.initials: VH
authors.lastname: Melo
mesh_terms: D000653:Amniotic Fluid / Q000821:virology*; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D019562:Viral Load