Impact of aging on viral infections.
Older people are more susceptible to a variety of viral infections, including those that induce respiratory disease, resulting in higher morbidity and mortality than younger people. Aging impacts both innate and adaptive arms of the immune system to impair control of viral infections. This review will summarize key findings on how aging impacts immunity to viral infection.
Leng
Jin
J
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Goldstein
Daniel R
DR
D056704:Adaptive Immunity / Q000502:physiology; D000375:Aging; D006801:Humans; D007113:Immunity, Innate / Q000502:physiology; D014777:Virus Diseases / Q000276:immunology* / Q000401:mortality / Q000473:pathology*