Giant ossifying malignant thymoma in a child.
We present the first reported case of an ossifying pediatric thymoma. Our patient was diagnosed with a massive thymoma replacing the whole of the left thoracic cavity. Percutaneous biopsy was attempted 3 times followed by an open incisional biopsy and adjuvant chemotherapy. Complete resection required a median sternotomy and a "trap door" thoracotomy after the tumor failed to respond to chemotherapy. Histology confirmed World Health Organization type B1 lymphocyte-rich thymoma, Masaoka stage I, with extensive osseous metaplasia.
Bikhchandani
Jai
J
Department of Surgery, The Children's Mercy Hospital, Kansas City, MO 64108, USA.
Valusek
Patricia A
PA
Juang
David
D
E O'Brien
James
J
Hetherington
Maxine
M
St Peter
Shawn D
SD
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D009999:Ossification, Heterotopic; D013945:Thymoma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D013953:Thymus Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*