Genetics of addictions.
Addictions include a group of common, heritable psychiatric illnesses that have multiple psychiatric and medical comorbidities. Robust genetic associations have been found for alcohol dependence, nicotine dependence, and cocaine dependence. Common genetic associations have been found between alcohol dependence and aerodigestive cancers and between nicotine dependence and lung disease. These associations highlight the importance of understanding the genetics of substance dependence in the context of its multiple medical and psychiatric comorbidities.
Hartz
Sarah M
SM
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 South Euclid Avenue, St Louis, MO 63110-1093, USA.
Bierut
Laura J
LJ
D056726:Genetic Association Studies; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics; D001523:Mental Disorders / Q000235:genetics; D029424:Pulmonary Disease, Chronic Obstructive / Q000235:genetics; D019966:Substance-Related Disorders / Q000235:genetics*