Programmable microfluidic patterning of protein gradients on hydrogels.
Computer-controlled hydrodynamic flow focusing was utilized to generate tethered protein gradients of any user-defined shape on the surface of soft synthetic hydrogels.
Allazetta
Simone
S
Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne Station 15 Bldg. AI 1109, CH-1015 Lausanne, Switzerland.
Cosson
Steffen
S
Lutolf
Matthias P
MP
D003198:Computer Simulation; D057446:Hydrodynamics; D020100:Hydrogels / Q000138:chemical synthesis / Q000737:chemistry*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D015394:Molecular Structure; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry; D011506:Proteins / Q000737:chemistry*; D012984:Software; D013499:Surface Properties
D020100:Hydrogels; D011506:Proteins; D011092:Polyethylene Glycols