title: Polyethylene insert damage in unicondylar knee replacement: a comparison of in vivo function and in vitro simulation.
abstract: Modification of knee joint wear simulation methods has included 'anatomic attachment' of unicondylar knee replacements (UKR) onto synthetic femurs with material properties and morphology similar to human femurs. The present study assesses the effect of such modification by comparing the damage patterns on UKR polyethylene inserts after in vitro simulation using standard and modified simulation methods with those on inserts retrieved after in vivo function. Three groups of UKR inserts were evaluated after retrieval (Explant Group, n = 17) or after knee joint wear simulation with the components attached to standard metal blocks (Standard Group, n = 6) or synthetic femurs (Anatomic Group, n = 6). All UKR had similar non-conforming articular surfaces. Articular damage patterns (mode, frequency, and area) were quantified using digital image photogrammetry. Although some common damage modes were noted, knee joint wear simulation with standard or 'anatomic' attachment did not generate damage pattern sizes similar to the explanted UKR. A focal damage pattern consistent with contact between the metal femoral articular surface and the polyethylene inserts was evident on all inserts, but only the Explant Group had evidence of dispersed damage dominated by abrasive modes. Synthetic femurs added complexity to the wear simulation without generating wear patterns substantially more similar to those observed on retrieved inserts.
authors.affiliation: Laboratorio di Tecnologia Medica, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Harman
authors.forename: S
authors.initials: S
authors.lastname: Affatato
authors.forename: M
authors.initials: M
authors.lastname: Spinelli
authors.forename: M
authors.initials: M
authors.lastname: Zavalloni
authors.forename: S
authors.initials: S
authors.lastname: Stea
authors.forename: A
authors.initials: A
authors.lastname: Toni
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D019544:Equipment Failure Analysis; D006801:Humans; D066298:In Vitro Techniques; D007720:Knee Prosthesis; D008422:Materials Testing; D008954:Models, Biological; D020959:Polyethylene; D011474:Prosthesis Design
chemical_list: D020959:Polyethylene