title: Domino Michael-O-alkylation: one-pot synthesis of dialkyl 4-oxo-2,3-dihydro-2,3-furandicarboxylates.
abstract: The KSCN-catalyzed reaction of dialkyl acetylenedicarboxylates with pentane-2,4-dione in acetone, led to dialkyl 2-(1-acetyl-2-oxopropyl)-2-butenedioates in excellent yields. When these reactions were carried out in MEK (butane-2-one), dialkyl 4-oxo-2,3-dihydro-2,3-furandicarboxylates were obtained exclusively. This difference in reactivity is discussed in terms of the possibility of cationic exchange in butane-2-one.
authors.affiliation: Chemistry Department, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran. yavarisa@modares.ac.ir
authors.forename: Issa
authors.initials: I
authors.lastname: Yavari
authors.forename: Mehdi
authors.initials: M
authors.lastname: Sirouspour
authors.forename: Sanaz
authors.initials: S
authors.lastname: Souri
mesh_terms: D000478:Alkylation; D002384:Catalysis; D002621:Chemistry / Q000379:methods*; D005663:Furans / Q000138:chemical synthesis*
chemical_list: D005663:Furans