Polyketides from Eleutherine bulbosa.
Four new polyketides, (R)-4-hydroxyeleutherin, eleuthone, eleutherinol-8-O-β-D-glucoside and isoeleuthoside C (dihydroisoeleutherin-5-O-β-D-gentiobioside) were isolated from the bulbs of Eleutherine bulbosa, to join eleutherin, isoeleutherin, eleutherinol, eleutherol, eleuthoside B (eleutherol-4-O-β-D-gentiobioside), eleuthoside C (dihydroeleutherin-5-O-β-D-gentiobioside), hongconin (4-oxodihydroisoeleutherin) and elecanacin, which have already been isolated from the same plant. The structures of the new polyketides, based on oxydated cyclic systems, have been elucidated by chemical and spectroscopic methods.
Gallo
Francesca R
FR
Dipartimento del Farmaco, Istituto Superiore di Sanita, I-00161 Rome, Italy. francesca.gallo@iss.it
Palazzino
Giovanna
G
Federici
Elena
E
Iurilli
Raffaella
R
Galeffi
Corrado
C
Chifundera
Kusamba
K
Nicoletti
Marcello
M
D027621:Iridaceae / Q000737:chemistry*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry
D018942:Macrolides