Palladium-catalyzed oxidative cross-coupling reaction of arylboronic acids with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates.
A Pd-catalyzed oxidative cross-coupling reaction of arylboronic acids with α-diazoesters was achieved using molecular oxygen as the sole reoxidant, and E-α,β-diarylacrylates were obtained in good yields and >20:1 E-to-Z selectivity.
Tsoi
Yuk-Tai
YT
State Key Laboratory for Chirosciences and Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Zhou
Zhongyuan
Z
Chan
Albert S C
AS
Yu
Wing-Yiu
WY
D000179:Acrylates / Q000138:chemical synthesis*; D001391:Azo Compounds / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000179:Acrylates; D001391:Azo Compounds; D001896:Boron Compounds; D001897:Boronic Acids; C006666:azoester; D010165:Palladium; C036658:acrylic acid