Flow cytometric detection of degranulated basophils in chronic myeloid leukemia in accelerated phase.
We report a rare case of chronic myeloid leukemia in accelerated phase with basophilic transformation, in which basophils exceeding 70%, were detectable only by flow cytometry because of their morphologic atypicality and degranulation.
Stacchini
Alessandra
A
Flow Cytometry Unit, Molinette Hospital, Turin, Italy. astacchini@molinette.piemonte.it
Demurtas
Anna
A
Godio
Laura
L
D000368:Aged; D015703:Antigens, CD / Q000096:biosynthesis / Q000276:immunology; D001491:Basophils / Q000276:immunology / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D005434:Flow Cytometry; D006801:Humans; D016130:Immunophenotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D008297:Male
D015703:Antigens, CD