Circulation of hantaviruses in the influence area of the Cuiabá-Santarém Highway.
We describe evidence of circulation of hantaviruses in the influence area of the Santarém-Cuiabá Highway (BR-163) in the Brazilian Amazon through the prevalence of specific antibodies against hantaviruses in inhabitants living in four municipalities of this area: Novo Progresso (2.16%) and Trairão (4.37%), in state of Pará (PA), and Gua-rantã do Norte (4.74%) and Marcelândia (9.43%), in state of Mato Grosso. We also demonstrate the ongoing association between Castelo dos Sonhos virus (CASV) and hantavirus pulmonary syndrome (HPS) cases in the Castelo dos Sonhos district (municipality of Altamira, PA) and the first report of CASV in the municipalities of Novo Progresso and Guarantã do Norte. The results of this work highlight the risk for a possible increase in the number of HPS cases and the emergence of new hantavirus lineages associated with deforestation in this Amazonian area after the conclusion of paving works on BR-163 Highway.
Medeiros
Daniele B A
DB
Secretaria de Saúde do Estado do Mato Grosso, Cuiabá, MT, Brasil.
da Rosa
Elizabeth S Travassos
ES
Marques
Aparecido  A R
A
Simith
Darlene B
DB
Carneiro
Adriana R
AR
Chiang
Jannifer O
JO
Prazeres
Ivy T E
IT
Vasconcelos
Pedro F C
PF
Nunes
Márcio R T
MR
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D006476:Orthohantavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D018778:Hantavirus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D018804:Hantavirus Pulmonary Syndrome / Q000821:virology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000235:genetics*; D012621:Seasons; D016036:Seroepidemiologic Studies; D055815:Young Adult
D000914:Antibodies, Viral; D012367:RNA, Viral