title: Safety and efficacy of a novel continence device in colostomy patients.
abstract: OBJECTIVE
  This study aimed to assess the safety and efficacy of a novel colostomy continence device.
  
  
  METHODS
  This phase II, 142-day, open-label, nonrandomized, multicenter study enrolled patients who had end colostomies for ≥3 months. Study stages were usual pouching (21 days), wafer transition (14 days), and the device (107 days). During device wear, up to 8 hours per day, patients recorded the following outcomes in daily diaries: skin condition (if the wafer was changed); stoma color, moisture, and physical condition; and gastrointestinal symptoms.
  
  
  RESULTS
  Of the 26 patients enrolled, 25 wore at least one device. The device was worn on 96% of study days and a mean of 6.8 hours per day. Adverse events were reported by 1 patient during the usual pouching 21-day period, by 5 patients during the wafer transition 14-day period, and by 15 patients during the device wear 107-day period. Stoma color and moisture were within normal range on all daily assessments. The device did not affect microbiology or vascularity. During device wear, patients had no unusual gastrointestinal symptoms or odor on >99% and 80% of days, respectively. The mean number of leaks per patient-month was 1.2 with usual pouching, 4.2 with the device overall, and 2.1 during the last 3 weeks with the device, suggesting a learning curve. Approximately 65% of patients preferred the device to usual pouching at the end of study.
  
  
  CONCLUSIONS
  The novel continence device was safe and effective for up to 8 hours per day in colostomy patients.
authors.affiliation: Image Specialties, St. Joseph, Missouri 64506, USA. terrimaxwell@netzero.com
authors.forename: Terri R
authors.initials: TR
authors.lastname: Maxwell
authors.forename: Denice
authors.initials: D
authors.lastname: Taylor
authors.forename: Ann M
authors.initials: AM
authors.lastname: Durnal
authors.forename: Rebecca
authors.initials: R
authors.lastname: Wills
authors.forename: Dheerendra
authors.initials: D
authors.lastname: Kommala
authors.forename: Scott
authors.initials: S
authors.lastname: Wade
mesh_terms: D000328:Adult; D000368:Aged; D039021:Colonic Pouches; D003125:Colostomy / Q000009:adverse effects / Q000295:instrumentation*; D004867:Equipment Design; D005242:Fecal Incontinence / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D005414:Flatulence / Q000453:epidemiology / Q000517:prevention & control*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009812:Odorants / Q000517:prevention & control; D017060:Patient Satisfaction; D054047:Surgical Stomas; D013997:Time Factors; D016896:Treatment Outcome