Management of psychosis associated with a prolactinoma: case report and review of the literature.
BACKGROUND
Prolactinomas are the most common pituitary tumors; they are treated with dopamine agonists, which may cause psychotic symptoms as a side effect. Psychosis is treated with dopamine-receptor blockers that may result in elevated serum prolactin and symptomatic hyperprolactinemia.


OBJECTIVE
The authors will review a case of a patient with a prolactinoma as well as schizophrenia and illustrate the management of psychosis in this case.


METHODS
The review describes the management of prolactinoma, symptoms of hyperprolactinemia, and long-term effects of hyperprolactinemia.


RESULTS
In the case presentation reviewed, the patient was finally discharged on risperidone long-acting injection and testosterone supplementation, with no growth of the adenoma after 3 years.


CONCLUSIONS
This review provides recommendations and treatment strategy for management of prolactinoma in a patient with schizophrenia.
Ali
Shirin
S
McLean Hospital, Boston, MA, USA. alishir@pi.cpmc.columbia.edu
Miller
Karen Klahr
KK
Freudenreich
Oliver
O
D000328:Adult; D018491:Dopamine Agonists / Q000009:adverse effects / Q000627:therapeutic use; D018492:Dopamine Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy
D018491:Dopamine Agonists; D018492:Dopamine Antagonists; D011388:Prolactin; D018967:Risperidone