title: Outcomes of 3% green tea emulsion on skin sebum production in male volunteers.
abstract: This study was aimed to depict potential effects of stable formulation (water in oil emulsion), containing 3% green tea (Camellia sinensis L) extract on skin sebum production in healthy human volunteers. For this purpose formulation was designed using 3% ethanolic green tea extract and Abil®EM90 was used as an emulsifier. Formulation was applied to the cheeks of healthy human volunteers (n=10) for a period of 8 weeks. Measurements for skin sebum production were considered using Sebumeter MPA 5. Results were compiled and any effect produced by the formulation was justified statistically. It was observable that statistically significant (p < 0.5%) results were found for skin sebum production after long term application of the formulation. 3% formulation of green tea extract was ideal in all aspects and can be experienced in skin disorders like acne to further investigate its effects in unhealthy volunteers.
authors.affiliation: Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
authors.forename: Tariq
authors.initials: T
authors.lastname: Mahmood
authors.forename: Naveed
authors.initials: N
authors.lastname: Akhtar
authors.forename: Barkat Ali
authors.initials: BA
authors.lastname: Khan
authors.forename: Haji M Shoaib
authors.initials: HM
authors.lastname: Khan
authors.forename: Tariq
authors.initials: T
authors.lastname: Saeed
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000704:Analysis of Variance; D002392:Catechin / Q000737:chemistry / Q000494:pharmacology; D002626:Chemistry, Pharmaceutical; D003879:Dermatologic Agents / Q000494:pharmacology; D004655:Emulsions; D006801:Humans; D008297:Male; D009824:Ointments; D010936:Plant Extracts / Q000494:pharmacology; D012629:Sebum / Q000378:metabolism*; D012867:Skin / Q000187:drug effects* / Q000378:metabolism*; D013662:Tea
chemical_list: D003879:Dermatologic Agents; D004655:Emulsions; D009824:Ointments; D010936:Plant Extracts; D013662:Tea; D002392:Catechin