Anti-herpetic activities of chemical components from the Brazilian red alga Plocamium brasiliense.
The CH2Cl2 crude extract and a fraction enriched with halogenated monoterpenes of the Brazilian red alga Plocamium brasiliense were evaluated for cytotoxicity and against the virus HSV-1. The extract showed low cytotoxicity compared with the fraction containing monoterpenes. The crude extract showed, in vitro, a high reduction of infectivity of the virus HSV-1.
Ferreira
Wilton José
WJ
Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Amaro
Rodrigo
R
Cavalcanti
Diana Negrão
DN
de Rezende
Claudia Moraes
CM
da Silva
Viveca Antonia Giongo Galvão
VA
Barbosa
Juliana Eymara
JE
Paixão
Izabel Christina Nunes de Palmer
IC
Teixeira
Valéria Laneuville
VL
D000998:Antiviral Agents / Q000494:pharmacology*; D001938:Brazil; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D039821:Monoterpenes / Q000494:pharmacology*; D044725:Plocamium / Q000737:chemistry*
D000998:Antiviral Agents; D039821:Monoterpenes