title: Anti-herpetic activities of chemical components from the Brazilian red alga Plocamium brasiliense.
abstract: The CH2Cl2 crude extract and a fraction enriched with halogenated monoterpenes of the Brazilian red alga Plocamium brasiliense were evaluated for cytotoxicity and against the virus HSV-1. The extract showed low cytotoxicity compared with the fraction containing monoterpenes. The crude extract showed, in vitro, a high reduction of infectivity of the virus HSV-1.
authors.affiliation: Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors.forename: Wilton José
authors.initials: WJ
authors.lastname: Ferreira
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Amaro
authors.forename: Diana Negrão
authors.initials: DN
authors.lastname: Cavalcanti
authors.forename: Claudia Moraes
authors.initials: CM
authors.lastname: de Rezende
authors.forename: Viveca Antonia Giongo Galvão
authors.initials: VA
authors.lastname: da Silva
authors.forename: Juliana Eymara
authors.initials: JE
authors.lastname: Barbosa
authors.forename: Izabel Christina Nunes de Palmer
authors.initials: IC
authors.lastname: Paixão
authors.forename: Valéria Laneuville
authors.initials: VL
authors.lastname: Teixeira
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D001938:Brazil; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D039821:Monoterpenes / Q000494:pharmacology*; D044725:Plocamium / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D039821:Monoterpenes