Antibody responses to hepatitis A virus vaccination in thai hiv-infected children with immune recovery after antiretroviral therapy.
The prevalence of hepatitis A virus (HAV) protective antibody in 98 Thai HIV-infected children who achieved immune recovery after antiretroviral therapy was 12.2%. After a 2-dose HAV vaccination, 98.8% (85 of 86 children) seroconverted. The geometric mean titer was 520.95 mIU/mL. In a multivariate analysis, female gender, age < 12 years and higher CD4 lymphocyte count at enrollment were predicting factors for high (≥ 250 mIU/mL) HAV antibody response.
Sudjaritruk
Tavitiya
T
Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sirisanthana
Thira
T
Sirisanthana
Virat
V
D000293:Adolescent; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology*; D035922:Hepatitis A Antibodies / Q000097:blood*; D022362:Hepatitis A Vaccines / Q000276:immunology*; D006801:Humans; D008297:Male; D013785:Thailand
D019380:Anti-HIV Agents; D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines