title: Natural and synthetic antioxidants: an updated overview.
abstract: Abstract The current understanding of the complex role of ROS in the organism and pathological sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant reactivities and interactions with cellular constituents. Studies of antioxidants performed within the COST B-35 action has concerned the search for new natural antioxidants, synthesis of new antioxidant compounds and evaluation and elucidation of mechanisms of action of both natural and synthetic antioxidants. Representative studies presented in the review concern antioxidant properties of various kinds of tea, the search for new antioxidants of herbal origin, modification of tocopherols and their use in combination with selenium and properties of two promising groups of synthetic antioxidants: derivatives of stobadine and derivatives of 1,4-dihydropyridine.
authors.affiliation: Department of Analytical Chemistry, Medical University of Białystok, 14, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Augustyniak
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Bartosz
authors.forename: Ana
authors.initials: A
authors.lastname: Cipak
authors.forename: Gunars
authors.initials: G
authors.lastname: Duburs
authors.forename: L'ubica
authors.initials: L
authors.lastname: Horáková
authors.forename: Wojciech
authors.initials: W
authors.lastname: Luczaj
authors.forename: Magdalena
authors.initials: M
authors.lastname: Majekova
authors.forename: Andreani D
authors.initials: AD
authors.lastname: Odysseos
authors.forename: Lucia
authors.initials: L
authors.lastname: Rackova
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Skrzydlewska
authors.forename: Milan
authors.initials: M
authors.lastname: Stefek
authors.forename: Miriam
authors.initials: M
authors.lastname: Strosová
authors.forename: Gunars
authors.initials: G
authors.lastname: Tirzitis
authors.forename: Petras Rimantas
authors.initials: PR
authors.lastname: Venskutonis
authors.forename: Jana
authors.initials: J
authors.lastname: Viskupicova
authors.forename: Panagiota S
authors.initials: PS
authors.lastname: Vraka
authors.forename: Neven
authors.initials: N
authors.lastname: Zarković
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis* / Q000494:pharmacology*; D002243:Carbolines / Q000737:chemistry / Q000494:pharmacology; D004095:Dihydropyridines / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects*; D028321:Plant Preparations / Q000737:chemistry / Q000494:pharmacology; D018036:Selenium Compounds / Q000737:chemistry / Q000494:pharmacology; D013662:Tea / Q000737:chemistry; D024505:Tocopherols / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D002243:Carbolines; D004095:Dihydropyridines; D028321:Plant Preparations; D018036:Selenium Compounds; D013662:Tea; C038806:1,4-dihydropyridine; D024505:Tocopherols; C100106:dicarbine