Cutoff score of the sexual interest and desire inventory-female for diagnosis of hypoactive sexual desire disorder.
OBJECTIVE
To determine the most appropriate cutoff value for the Sexual Interest and Desire Inventory-Female (SIDI-F) score to discriminate between women with hypoactive sexual desire disorder (HSDD) and those with no female sexual dysfunction (FSD). The SIDI-F is a clinician-rated instrument consisting of 13 items designed to assess HSDD severity in women. The total score ranges from 0 to 51, with higher scores indicating better sexual function.


METHODS
Data from patients enrolled in a North American nontreatment study and a European nontreatment study were analyzed. Both studies were 4-week, prospective, multicenter trials designed to assess the reliability and validity of the SIDI-F. Only patients with HSDD or no FSD were included in this analysis. Receiver operating characteristics (ROC) analysis was used to determine the ability of the SIDI-F to differentiate between patients with HSDD and those with no FSD at baseline.


RESULTS
A total of 428 women were included in this analysis: 174 from North America (HSDD 113, no FSD 61) and 254 from Europe (HSDD 130, no FSD 124). In the North American study, a SIDI-F cutoff score of 33 minimized the difference between sensitivity (94.7%) and specificity (93.4%). In the European study, SIDI-F cutoff scores of both 33 and 34 minimized the difference between sensitivity (95.2%) and specificity (94.4%).


CONCLUSIONS
In appropriately screened women, a SIDI-F score of ≤33 indicates the presence of HSDD.
Clayton
Anita H
AH
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22903, USA. baydouha@evms.edu
Segraves
Robert T
RT
Bakish
David
D
Goldmeier
David
D
Tignol
Jean
J
van Lunsen
Rik H W
RH
Nappi
Rossella E
RE
Wunderlich
Glen
G
Kimura
Toshio
T
Lewis-D'Agostino
Diane J
DJ
Pyke
Robert
R
D000328:Adult; D003937:Diagnosis, Differential; D005060:Europe; D005260:Female; D006801:Humans; D007989:Libido / Q000502:physiology; D010555:Personality Inventory; D011446:Prospective Studies; D011594:Psychometrics; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D020018:Sexual Dysfunctions, Psychological / Q000175:diagnosis*; D011795:Surveys and Questionnaires; D014481:United States