title: Bioconcentration of selected endocrine disrupting compounds in the Mediterranean mussel, Mytilus galloprovincialis.
abstract: The occurrence of three endocrine disrupting compounds, 4-n-nonylphenol, triclosan and bisphenol A, was investigated in different bivalves originating from the Aegean Sea (Greece). The bioconcentration potential of these compounds was studied using the Mediterranean mussel (Mytilus galloprovincialis). Tissue samples were extracted by sonication. Analysis was performed by gas chromatography-mass spectrometry. According to the field survey results, the average concentrations of 4-n-nonylphenol, triclosan and bisphenol A, were 158, 461 and 404 ng g(-1) (dry weight), respectively. During 28 days of exposure at 300 ng L(-1), the tissue concentrations of compounds were constantly increased. Steady state was not observed up to the end of the experiment. Kinetic bioconcentration factors varied from 1.7 (4-n-nonylphenol and triclosan) to 4.5 L g(-1) (bisphenol A). Following exposure, mussels were relocated to clean water for 28 days. This experiment revealed that depuration rates for all of the target compounds were lower than uptake rates. The biological half-lives of each compound ranged between 12 days (triclosan) and 26 days (bisphenol A).
authors.affiliation: Department of Environment, University of the Aegean, Mytilene 81100, Greece. ggatid@env.aegean.gr
authors.forename: Georgia
authors.initials: G
authors.lastname: Gatidou
authors.forename: Eleftheria
authors.initials: E
authors.lastname: Vassalou
authors.forename: Nikolaos S
authors.initials: NS
authors.lastname: Thomaidis
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D006115:Greece; D006207:Half-Life; D049878:Mytilus / Q000737:chemistry*; D010636:Phenols / Q000493:pharmacokinetics*; D012623:Seawater; D014018:Tissue Distribution; D014260:Triclosan / Q000493:pharmacokinetics*; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D010636:Phenols; D014260:Triclosan; D014874:Water Pollutants, Chemical; C041594:4-nonylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds