Synthesis and antifungal activity of benzofuran-5-ols.
Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.
Ryu
Chung-Kyu
CK
College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea. ckryu@ewha.ac.kr
Song
Ae Li
AL
Lee
Jung Yoon
JY
Hong
Jung An
JA
Yoon
Joo Hee
JH
Kim
Aram
A
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects; D003455:Cryptococcus neoformans / Q000187:drug effects; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; D001572:Benzofurans