Bio-inspired amino acid oxidation by a non-heme iron catalyst modeling the action of 1-aminocyclopropane-1-carboxylic acid oxidase.
In this communication we describe the first example of a biomimetic mononuclear iron complex, [Fe(III)(Salen)Cl] (Salen = N,N'-bis(salicylidene)-ethylenediaminato), that highly selectively and efficiently catalyzes the oxidation of 1-aminocyclopropane-1-carboxylic acid (ACCH), α-aminoisobutyric acid (AIBH), and alanine (ALAH) to ethylene or the corresponding carbonyl compounds, mimicking the action of the non-heme iron enzyme 1-aminocyclopropane-1-carboxylic acid oxidase (ACCO).
Baráth
Gábor
G
Department of Chemistry, University of Pannonia, 8201 Veszprém, Hungary.
Kaizer
József
J
Pap
József Sándor
JS
Speier
Gábor
G
El Bakkali-Taheri
Nadia
N
Simaan
A Jalila
AJ
D000594:Amino Acid Oxidoreductases / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D006861:Hydrogen Peroxide / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D007700:Kinetics; D008958:Models, Molecular; D010084:Oxidation-Reduction; D013057:Spectrum Analysis / Q000379:methods
D000596:Amino Acids; D006861:Hydrogen Peroxide; D007501:Iron; D000594:Amino Acid Oxidoreductases; C059460:1-aminocyclopropane-1-carboxylic acid oxidase