title: Synthesis of substituted indoles from 2-azidoacrylates and ortho-silyl aryltriflates.
abstract: 2-Azidoacrylates react with benzynes in the presence of PPh(3) and CsF to afford substituted indoles in good yields. The reaction involves the formation of iminophosphorane and benzyne and a subsequent double cyclization/hydrolysis/air-oxidation cascade. This methodology was utilized to synthesize 10H-indolo[1,2-a]indol-10-ones.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China.
authors.forename: Deng
authors.initials: D
authors.lastname: Hong
authors.forename: Zhengbo
authors.initials: Z
authors.lastname: Chen
authors.forename: Xufeng
authors.initials: X
authors.lastname: Lin
authors.forename: Yanguang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007211:Indoles / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000737:chemistry*
chemical_list: D000179:Acrylates; D001386:Azides; D007211:Indoles; D017646:Organosilicon Compounds; C036658:acrylic acid