title: Location, location, location-makes all the difference for hypoxia in lung tumors.
abstract: Hypoxia is a clinically important component of the tumor microenvironment because it adversely affects progression, metastasis, response to chemoradiation therapy, and overall patient survival. Here, we describe how different animal tumor models of lung cancer can yield surprisingly different hypoxic profiles.
authors.affiliation: Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, 19104-6072, USA. maity@uphs.upenn.edu
authors.forename: Amit
authors.initials: A
authors.lastname: Maity
authors.forename: Constantinos
authors.initials: C
authors.lastname: Koumenis
mesh_terms: D000818:Animals; D015687:Cell Hypoxia; D045744:Cell Line, Tumor; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology*; D059016:Tumor Microenvironment