Diquaternized curarelike myorelaxants: structure and biological activity.
This review discusses the most active natural and synthetic curarelike compounds demonstrating myorelaxants activity. The data are grouped according to chemical structures, namely, quinoline and isoquinoline myorelaxants, myorelaxants with saturated heterocyclic or alkylamine fragments, myorelaxants with a steroid framework, natural and synthetic alkaloid myorelaxants.
Salakhutdinov
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N.N. Vorozhtsov Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia. anvar@nioch.nsc.ru
Tolstikov
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GA
D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology; D000588:Amines / Q000737:chemistry; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D003473:Neuromuscular Nondepolarizing Agents / Q000737:chemistry* / Q000494:pharmacology*; D011804:Quinolines / Q000737:chemistry / Q000494:pharmacology
D000470:Alkaloids; D000588:Amines; D001688:Biological Products; D003473:Neuromuscular Nondepolarizing Agents; D011804:Quinolines