title: Polihexanide for wound treatment--how it began.
abstract: The essential role of wound antiseptics was discovered in the 18th century. Since then, many different procedures and substances have been developed and used for this indication. In the 1980s, polihexanide was introduced by Prof. Willenegger in Switzerland. Today, consensus recommendations confirm the potential of this substance for wound treatment. Various polihexanide-containing wound care products are available and these are now also gaining in importance throughout Europe and throughout the world.
authors.affiliation: Bezirksspital Belp, Belp, Switzerland.
authors.forename: B
authors.initials: B
authors.lastname: Roth
authors.forename: F H H
authors.initials: FH
authors.lastname: Brill
mesh_terms: D000891:Anti-Infective Agents, Local / Q000009:adverse effects / Q000627:therapeutic use*; D000985:Antisepsis; D001645:Biguanides / Q000009:adverse effects / Q000627:therapeutic use*; D004337:Drug Carriers; D004352:Drug Resistance, Microbial; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D011092:Polyethylene Glycols; D012867:Skin; D007507:Therapeutic Irrigation / Q000009:adverse effects; D014946:Wound Infection / Q000188:drug therapy* / Q000266:history / Q000517:prevention & control
chemical_list: D000891:Anti-Infective Agents, Local; D001645:Biguanides; D004337:Drug Carriers; C031233:polihexanide; D011092:Polyethylene Glycols