title: Diels-Alder reactions of cyclic isoimidium salts.
abstract: Diels-Alder reactions of cyclic isoimidium salts are described. The corresponding cycloadducts are obtained with high regio- and stereoselectivity. The use of homochiral cyclic isoimidium salts delivers cycloadducts with excellent diastereoselectivity (>99:1) that can be efficiently converted to enantiomerically pure lactones.
authors.affiliation: Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, USA. rkb@rkbmac.chem.rochester.edu
authors.forename: Robert K
authors.initials: RK
authors.lastname: Boeckman
authors.forename: Yan
authors.initials: Y
authors.lastname: Miller
authors.forename: Todd R
authors.initials: TR
authors.lastname: Ryder
mesh_terms: D003500:Cyclization; D007094:Imides / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D007094:Imides