title: Synthesis of 3,3-disubstituted oxindoles by palladium-catalyzed tandem reaction of 2-(alkynyl)aryl isocyanates with benzylic alcohols.
abstract: A palladium complex sequentially promoted two mechanistically distinct reactions, the first, cyclization of 2-(alkynyl)aryl isocyanates with benzylic alcohols, and the second, [1,3] rearrangement of a benzyl group from oxygen to carbon, furnishing 3,3-disubstituted oxindoles in one pot.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan.
authors.forename: Takeharu
authors.initials: T
authors.lastname: Toyoshima
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Mikano
authors.forename: Tomoya
authors.initials: T
authors.lastname: Miura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami