title: Compensation of modelling errors due to unknown domain boundary in electrical impedance tomography.
abstract: Electrical impedance tomography is a highly unstable problem with respect to measurement and modeling errors. This instability is especially severe when absolute imaging is considered. With clinical measurements, accurate knowledge about the body shape is usually not available, and therefore an approximate model domain has to be used in the computational model. It has earlier been shown that large reconstruction artefacts result if the geometry of the model domain is incorrect. In this paper, we adapt the so-called approximation error approach to compensate for the modeling errors caused by inaccurately known body shape. This approach has previously been shown to be applicable to a variety of modeling errors, such as coarse discretization in the numerical approximation of the forward model and domain truncation. We evaluate the approach with a simulated example of thorax imaging, and also with experimental data from a laboratory setting, with absolute imaging considered in both cases. We show that the related modeling errors can be efficiently compensated for by the approximation error approach. We also show that recovery from simultaneous discretization related errors is feasible, allowing the use of computationally efficient reduced order models.
authors.affiliation: Department of Physics and Mathematics, University of Eastern Finland, FIN-70211 Kuopio, Finland.
authors.forename: Antti
authors.initials: A
authors.lastname: Nissinen
authors.forename: Ville Petteri
authors.initials: VP
authors.lastname: Kolehmainen
authors.forename: Jari P
authors.initials: JP
authors.lastname: Kaipio
mesh_terms: D001499:Bayes Theorem; D003198:Computer Simulation; D017097:Electric Impedance; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008962:Models, Theoretical; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D013909:Thorax / Q000033:anatomy & histology; D014054:Tomography / Q000379:methods*