Mechanism for the abiotic synthesis of uracil via UV-induced oxidation of pyrimidine in pure H(2)O ices under astrophysical conditions.
The UV photoirradiation of pyrimidine in pure H(2)O ices has been explored using second-order Moller-Plesset perturbation theory and density functional theory methods, and compared with experimental results. Mechanisms studied include those starting with neutral pyrimidine or cationic pyrimidine radicals, and reacting with OH radical. The ab initio calculations reveal that the formation of some key species, including the nucleobase uracil, is energetically favored over others. The presence of one or several water molecules is necessary in order to abstract a proton which leads to the final products. Formation of many of the photoproducts in UV-irradiated H(2)O:pyrimidine=20:1 ice mixtures was established in a previous experimental study. Among all the products, uracil is predicted by quantum chemical calculations to be the most favored, and has been identified in experimental samples by two independent chromatography techniques. The results of the present study strongly support the scenario in which prebiotic molecules, such as the nucleobase uracil, can be formed under abiotic processes in astrophysically relevant environments, namely in condensed phase on the surface of icy, cold grains before being delivered to the telluric planets, like Earth.
Bera
Partha P
PP
Space Science and Astrobiology Division, NASA Ames Research Center, Moffett Field, California 94035, USASETI Institute, Mountain View, California 94043, USA. partha.p.bera@nasa.gov
Nuevo
Michel
M
Milam
Stefanie N
SN
Sandford
Scott A
SA
Lee
Timothy J
TJ
D055580:Astronomical Phenomena; D056004:Molecular Dynamics Simulation; D010084:Oxidation-Reduction; D011743:Pyrimidines / Q000737:chemistry*; D011789:Quantum Theory; D014466:Ultraviolet Rays; D014498:Uracil / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D011743:Pyrimidines; D014867:Water; D014498:Uracil; C030986:pyrimidine