[Studies on the chemical constituents of Kalimeris indica].
OBJECTIVE
To study the chemical constituents from Kalimeris indica.


METHODS
Compounds were isolated and purified with silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis including MS and NMR.


RESULTS
Nine compounds were isolated and identified as tritriacontane (I), hexadecanol (II), chrysophanol (III), vanillin (IV), physcion (V), beta-sitosterol (VI), stigmasterol (VII), leinoleic acid (VII), emodin (IX).


CONCLUSIONS
All of them, except compound IV, VI, are isolated from this genus for the first time. Compound III, IV had the protective effects with the toxicity of CCl4 on primary cultered hepatocytes.
Wang
Gang
G
School of Materia Madica, Anhui University of Traditional Chinese Medicine, Anhui Key Laboratory of Modernized Chinese Material Medical, Hefei 230031, China. kunhong_8@163.com
Wang
Guo-Kai
GK
Liu
Jin-Song
JS
Yu
Bo
B
Wang
Fei
F
Liu
Ji-Kai
JK
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification* / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002251:Carbon Tetrachloride; D002470:Cell Survival; D002478:Cells, Cultured; D056486:Chemical and Drug Induced Liver Injury; D004642:Emodin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005233:Fatty Alcohols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D022781:Hepatocytes / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D010232:Paraffin / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000880:Anthraquinones; D000893:Anti-Inflammatory Agents; D001547:Benzaldehydes; D005233:Fatty Alcohols; D012855:Sitosterols; C025473:gamma-sitosterol; C070808:tritriacontane; D010232:Paraffin; C100058:vanillin; D002251:Carbon Tetrachloride; C008905:physcione; D004642:Emodin; C027113:chrysophanic acid