title: Extrarenal Wilms tumor in children with unfavorable histology: a case report.
abstract: Extrarenal Wilms tumor is extremely rare, and only 25 cases in children have been reported to date in Japan. A 2-year-old girl presented with a large left lower quadrant abdominal mass. Abdominal computed tomography revealed a retroperitoneal tumor located below the left kidney. At laparotomy, the tumor was encapsulated without evidence of metastasis to other abdominal organs. Pathologic diagnosis of the tumor was extrarenal Wilms tumor with diffuse anaplasia. After complete tumor resection, chemotherapy was administered according to the treatment protocol (Regimen I) of the Japan Wilms Tumor Study Group. Cyclophosphamide and etoposide were administered in combination with vincristine and doxorubicin. Two years after treatment, the patient has had no evidence of recurrence.
authors.affiliation: Department of Pediatric Surgery, Saga Prefectural Hospital KOSEIKASN, Saga, Japan. taguchi1967@gmail.com
authors.forename: Shohei
authors.initials: S
authors.lastname: Taguchi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shono
authors.forename: Daisuke
authors.initials: D
authors.lastname: Mori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Horie
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006801:Humans; D012186:Retroperitoneal Neoplasms / Q000473:pathology* / Q000628:therapy; D009396:Wilms Tumor / Q000473:pathology* / Q000628:therapy