title: Incidence of endophthalmitis after 20-gauge vs 23-gauge vs 25-gauge pars plana vitrectomy.
abstract: OBJECTIVE
  To compare endophthalmitis rates after 20-gauge versus 23-gauge versus 25-gauge pars plana vitrectomy (PPV) in 2007-2008, and compare the rates with those of 2005-2006.
  
  
  METHODS
  Multicenter study including all patients who developed endophthalmitis following PPV performed by any of the authors during 2005-2008, and all patients who developed endophthalmitis following PPV at Penn State College of Medicine and Bascom Palmer Eye Institute during 2005-2008. The endophthalmitis rates after 20-gauge, 23-gauge and 25-gauge PPV during 2007-2008 were compared to those from 2005-2006.
  
  
  RESULTS
  The endophthalmitis incidence during 2007-2008 was 1/4,403 (0.02%) for 20-gauge PPV, 1/3,362 (0.03%) for 23-gauge PPV, and 1/789 (0.13%) for 25-gauge PPV. There is no significant difference among these rates between any two of the three groups. Compared with the endophthalmitis rates among the same group of surgeons during 2005-2006, the 2007-2008 endophthalmitis rates following 20-gauge and 23-gauge PPV were stable, and the rate following 25-gauge PPV was marginally lower (p = 0.056; odds ratio = 0.15; 95% CI: (0.003, 1.03)).
  
  
  CONCLUSIONS
  There was no significant difference in the 2007-2008 rates of endophthalmitis following 20-gauge versus 23-gauge versus 25-gauge PPV; among the same group of surgeons, the 2007-2008 rate of endophthalmitis following 25-gauge PPV was marginally lower than the 2005-2006 rate.
authors.affiliation: Departments of Ophthalmology and Public Health Sciences, Penn State College of Medicine, 500 University Drive, HU19, Hershey, PA 17083-0850, USA. iscott@psu.edu
authors.forename: Ingrid U
authors.initials: IU
authors.lastname: Scott
authors.forename: Harry W
authors.initials: HW
authors.lastname: Flynn
authors.forename: Nur
authors.initials: N
authors.lastname: Acar
authors.forename: Sundeep
authors.initials: S
authors.lastname: Dev
authors.forename: Saad
authors.initials: S
authors.lastname: Shaikh
authors.forename: Robert A
authors.initials: RA
authors.lastname: Mittra
authors.forename: J Fernando
authors.initials: JF
authors.lastname: Arevalo
authors.forename: Andres
authors.initials: A
authors.lastname: Kychenthal
authors.forename: Allen
authors.initials: A
authors.lastname: Kunselman
mesh_terms: D000368:Aged; D009877:Endophthalmitis / Q000453:epidemiology* / Q000382:microbiology; D019773:Epiretinal Membrane / Q000601:surgery; D015818:Eye Infections, Bacterial / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008866:Microsurgery / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000601:surgery; D012167:Retinal Perforations / Q000601:surgery; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*