title: Necrotizing fasciitis of the head and neck.
abstract: BACKGROUND
  Necrotizing fasciitis of the head and neck is a rapidly progressing and life-threatening condition. The purpose of this study was to describe the patients with a focus on clinical presentation, microbiology, treatment, and prognosis.
  
  
  RESULTS
  Seventeen patients (10 men; median age, 54 years) were included. Nine patients underwent minor head and neck surgery immediately prior to necrotizing fasciitis. The typical course was a quickly spreading erythema, pronounced tenderness, and severe pain. Imaging demonstrated diffuse swelling of the soft tissue, poorly differentiated dilated fat layers, and subcutaneous gas. All patients underwent surgical debridement within 2 days, and received broad-spectrum antibiotics and hemodynamic support, hyperbaric oxygen, and immunoglobulin. All patients survived, although 12 of 17 suffered sequelae.
  
  
  CONCLUSIONS
  Early diagnosis is of utmost importance. Quickly spreading erythema and extreme pain in the affected area serve as red flags. With the current intensive multimodality regimen, the mortality was zero, although 70% suffered sequelae.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Henning
authors.initials: H
authors.lastname: Wolf
authors.forename: Maria
authors.initials: M
authors.lastname: Rusan
authors.forename: Karin
authors.initials: K
authors.lastname: Lambertsen
authors.forename: Therese
authors.initials: T
authors.lastname: Ovesen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology / Q000628:therapy; D005260:Female; D006257:Head; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck; D011379:Prognosis; D055815:Young Adult