Unusual high rate of asymptomatic maternal parvovirus B19 infection associated with severe fetal outcome.
OBJECTIVE
To study the role of asymptomatic maternal parvo B19 infection in severe fetal outcome in Province of Vojvodina.


METHODS
One hundred seventy-six pregnant women (13-25 weeks of gestation) were divided in two groups - patients with symptoms of imminent spontaneous abortion and poor pregnancy outcome and patients with normal course of pregnancy. Double serum samples were analyzed to quantify IgM and IgG to parvovirus B19.


RESULTS
Among pregnant women with symptoms of spontaneous abortion, we found significantly higher percentage of acute parvovirus B19 infection.


CONCLUSIONS
Asymptomatic parvo B19 infection is associated with poor fetal outcome much more than we presumed previously.
Brkic
Snezana
S
Department of Infectious Diseases, Clinical Centre Vojvodina, Novi Sad, 21000 Serbia.
Bogavac
Mirjana A
MA
Simin
Natasa
N
Hrnjakovic-Cvetkovic
Ivana
I
Milosevic
Vesna
V
Maric
Danijela
D
D000293:Adolescent; D000328:Adult; D005260:Female; D005313:Fetal Death / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology*; D018445:Infectious Disease Transmission, Vertical / Q000706:statistics & numerical data; D010322:Parvoviridae Infections / Q000150:complications / Q000151:congenital / Q000453:epidemiology* / Q000635:transmission; D016732:Parvovirus B19, Human / Q000502:physiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012720:Severity of Illness Index; D055815:Young Adult