title: [A case with parotid carcinoma showing a pathologically complete response after treatment with S-1 alone].
abstract: We report a 57-year-old male case of adenocarcinoma of the parotid gland with metastases to the cervical lymph nodes (T3N2bM0, Stage IV A). S-1 was administered at the conventional dose of 120mg/day for 4 weeks followed by a 2-week rest. After 4 courses of S-1, PET findings showed a remarkable regression of the tumor resulting in a partial response (PR) for the primary lesion. After this treatment, partial parotidectomy and upper neck dissection were performed. The histological effect was Grade 3.
authors.affiliation: Dept. of Head and Neck Surgery, Chiba Cancer Center, Japan.
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Doi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Takanori
authors.initials: T
authors.lastname: Asano
mesh_terms: D001706:Biopsy; D003131:Combined Modality Therapy; D004338:Drug Combinations; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D010307:Parotid Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D049268:Positron-Emission Tomography; D012074:Remission Induction; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid