Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor.
Tcherniuk
Sergey
S
IBS (CEA-CNRS-UJF), 41, rue Jules Horowitz, 38027 Grenoble, France.
Skoufias
Dimitrios A
DA
Labriere
Christophe
C
Rath
Oliver
O
Gueritte
Françoise
F
Guillou
Catherine
C
Kozielski
Frank
F
D000181:Acrylonitrile / Q000031:analogs & derivatives* / Q000494:pharmacology; D064107:Aurora Kinase B; D064127:Aurora Kinases; D002503:Centromere; D007211:Indoles / Q000494:pharmacology*; D051034:Inhibitor of Apoptosis Proteins; D016547:Kinesins / Q000037:antagonists & inhibitors*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D008941:Spindle Apparatus; D000077022:Survivin
C555533:2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile; C107489:BIRC5 protein, human; D007211:Indoles; D051034:Inhibitor of Apoptosis Proteins; C410089:KIF20A protein, human; D008869:Microtubule-Associated Proteins; D000077022:Survivin; C576921:AURKB protein, human; D064107:Aurora Kinase B; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases; D016547:Kinesins; D000181:Acrylonitrile