title: Large congenital corneal dermoid with spontaneous partial regression: the first report.
abstract: OBJECTIVE
  To report a spontaneous partial regression of a large congenital corneal dermoid in a newborn.
  
  
  METHODS
  Review and follow-up of the medical records of a female newborn presenting with a tumor mass of her right eye and no other congenital abnormalities. The child presented on the first day of life with a mushroom-shaped mass of 15 × 15 mm in diameter that involved the most of the cornea leaving a small clear portion superiorly. The mass protruded through the palpebral aperture. A diagnosis of corneal dermoid was made based on clinical presentation of the mass and radiographic and ultrasound findings. Enucleation of the right eye was discussed, but declined by parents.
  
  
  RESULTS
  During the first month of life, a spontaneous partial regression of the mass occurred, so that the patient was able to close the lids completely above the mass. This dermoid is the third type according to Mann's classification. Characterized by involvement of the entire anterior segment and lack of lens.
  
  
  CONCLUSIONS
  To the best of our knowledge, the case reported is the first documented spontaneous partial regression of a large corneal dermoid. Surgical excision at an early age may be recommended to avoid development of amblyopia and dramatic growth of the tumor. In our case the tumor regressed and surgical excision would have no impact on visual outcome. Future management of type III corneal dermoid needs to consider whether to perform surgery at an early stage or to recommend conservative management.
authors.affiliation: Department of Ophthalmology, Clinical Hospital Sveti Duh, Zagreb, Croatia. mbjelos@mef.hr
authors.forename: Mirjana Bjeloš
authors.initials: MB
authors.lastname: Rončević
authors.forename: Jelena Petrinović
authors.initials: JP
authors.lastname: Dorešić
authors.forename: Ljubica Dorn
authors.initials: LD
authors.lastname: Md
mesh_terms: D003316:Corneal Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D003884:Dermoid Cyst / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D012075:Remission, Spontaneous; D014463:Ultrasonography