title: Nicotine gum dependence treated with varenicline--a case report.
abstract: BACKGROUND
  The buccal absorption of nicotine replacement therapy is a part of the treatment to quit smoking. In some cases, this use could last more than six months.
  
  
  RESULTS
  We report the case of a woman, former smoker, who took nicotine gums for over five years and was treated successfully with Varenicline during six months according to the recommended posology.
  
  
  CONCLUSIONS
  Varenicline, a partial alpha 4 beta 2 nicotinic receptor agonist, could be a solution to help former smokers to stop long-term use of nicotine gums or lozenges. Further studies will be necessary to confirm this result.
authors.affiliation: Unité Tabac, Groupe Hospitalier Pitié-Salpétrière-Assistance Publique-Hôpitaux de Paris, 47-83 Bd de l'Hôpital, 75651 Paris Cedex 13, France. dangarelik@aol.com
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Garelik
mesh_terms: D000328:Adult; D001552:Benzazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D018722:Nicotinic Agonists / Q000627:therapeutic use*; D011810:Quinoxalines / Q000627:therapeutic use*; D016540:Smoking Cessation / Q000379:methods*; D014029:Tobacco Use Disorder / Q000188:drug therapy*; D016896:Treatment Outcome; D000068580:Varenicline
chemical_list: D001552:Benzazepines; D018722:Nicotinic Agonists; D011810:Quinoxalines; D000068580:Varenicline