[Analyzing the production of organic acid of different genotype streptococcus mutans isolated from children with different caries experience].
OBJECTIVE
To compare the production of organic acid of different genotype Streptococcus mutans (S. mutans) isolated from children with different caries experience.


METHODS
66 strains of S.mutans isolated from dental plaques of children aged from 3 to 5 with different caries experience were chosen as test bacteria. The quantities of organic acid include formic acid, acetic acid and lactic acid which produced by different genotype of S. mutans, were measured by gas chromatograph.


RESULTS
There were significant difference in production of organic acid among the different genotypes of S. mutans isolated from children with different caries susceptibility, and so were the strains isolated from children within the same caries susceptibility (P < 0.05). The more genotypes the strain had, the more organic acid it produced (P < 0.05). Among all the organic acid, the quantity of lactic acid was much more than that of formic acid and acetic acid.


CONCLUSIONS
There were significant difference in the ability of the strains with different genotypes to produce organic acid, and the more genotypes it has, the more organic acid it produced.
Liu
Xing-rong
XR
Dept. of Oral Medicine, Hospital of Stomatology, Luzhou Medical College, Luzhou 646000, China.
Li
Jing
J
D002264:Carboxylic Acids / Q000378:metabolism*; D002675:Child, Preschool; D003731:Dental Caries / Q000382:microbiology*; D003773:Dental Plaque / Q000382:microbiology; D005838:Genotype; D006801:Humans; D013295:Streptococcus mutans / Q000235:genetics* / Q000378:metabolism
D002264:Carboxylic Acids