Using Cochrane reviews for oral diseases.
OBJECTIVE
To provide readers with information about the Cochrane Oral Health Group and how the reviews on oral diseases have contributed to guideline developments and the commissioning of trials.


METHODS
Examples have been selected from the reviews published on The Cochrane Library. Descriptions are given of how these reviews have been used in guideline development and commissioning of trials. Readers are updated on reviews focused on the management of oral cancer and the new venture of diagnostic test reviews.


RESULTS
Reviews on the management of oral diseases due to cancer treatments have been included in guidelines and changed practice in the UK. Cochrane reviews on Bell's Palsy have led to a randomised controlled trial which has changed the evidence base. The Cochrane review on recall intervals between routine appointments has input into the NICE guideline and resulted in a randomised controlled trial to look at different intervals including a risk-based interval.


CONCLUSIONS
We hope this article will give readers information on the work of the Cochrane Oral Health Group and insight into the diversity of reviews in oral diseases. The reviews are successfully being used to change practice and as background for the funding of large-scale clinical trials.
Worthington
H V
HV
Cochrane Oral Health Group, School of Dentistry, The University of Manchester, UK. helen.worthington@manchester.ac.uk
Glenny
A-M
AM
Mauleffinch
L Fernandez
LF
Daly
F
F
Clarkson
J
J
D000970:Antineoplastic Agents / Q000009:adverse effects; D001071:Appointments and Schedules; D020330:Bell Palsy / Q000628:therapy; D002986:Clinical Trials as Topic; D018849:Controlled Clinical Trials as Topic; D016208:Databases, Factual; D055094:Evidence-Based Dentistry; D006801:Humans; D033181:Information Dissemination; D008403:Mass Screening / Q000592:standards; D009059:Mouth Diseases / Q000209:etiology / Q000517:prevention & control; D009062:Mouth Neoplasms / Q000628:therapy; D009369:Neoplasms / Q000188:drug therapy; D017712:Peer Review, Research; D017410:Practice Guidelines as Topic; D011313:Preventive Dentistry; D016032:Randomized Controlled Trials as Topic; D012042:Registries; D012196:Review Literature as Topic; D018570:Risk Assessment; D013997:Time Factors; D006113:United Kingdom
D000970:Antineoplastic Agents