Dietary intake and the risk of hyperuricemia, gout and chronic kidney disease in elderly Taiwanese men.
BACKGROUND
This study was conducted to examine the relationship between dietary intake and the risk of chronic kidney disease (CKD), treated hyperuricemia (or gout) without CKD, and untreated hyperuricemia without CKD in elderly men.


METHODS
The study population comprised 752 men aged 65 or older who had been included in the Elderly Nutrition and Health Survey (1999-2000) (Elderly NAHSIT).


RESULTS
Statistical analysis using a polychotomous logistic regression model revealed that compared with the individuals in the normouricemic group, the individuals in the other groups exhibited a significant association between a higher prevalence of CKD and the following factors: advanced age, drug use for hypertension, egg and shellfish consumption and consumption of poultry with the skin and meat with fat. The significant risk factors for the patients who did not have CKD and were undergoing treatment for hyperuricemia were as follows: BMI ≥ 25 kg/m(2); drug use for hypertension; intake of poultry with skin; increased daily consumption of shellfish, fried food, sugar and juice.


CONCLUSIONS
Men who use anti-hypertensive drugs and who consume fewer soy products and more shellfish may be at a higher risk of developing hyperuricemia or CKD.
Chang
Wan-Chi
WC
Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan. r2891103@nckualumni.org.tw
D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002908:Chronic Disease; D015897:Comorbidity; D004032:Diet / Q000009:adverse effects / Q000523:psychology; D005247:Feeding Behavior; D005919:Glomerular Filtration Rate; D006073:Gout / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D033461:Hyperuricemia / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D007674:Kidney Diseases / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D014527:Uric Acid / Q000097:blood
D000959:Antihypertensive Agents; D014527:Uric Acid