title: Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives.
abstract: The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.
authors.affiliation: Department of Chemistry, University of Bath, Claverton Down, Bath, UKBA2 7AY.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Hargrave
authors.forename: Gerwyn
authors.initials: G
authors.lastname: Bish
authors.forename: Gabriele Kociok
authors.initials: GK
authors.lastname: Köhn
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Frost
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D008956:Models, Chemical; D023303:Oxazolidinones / Q000737:chemistry; D011522:Protons; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D001897:Boronic Acids; D023303:Oxazolidinones; D011522:Protons; D012238:Rhodium