Distribution of filamentous fungi causing invasive fungal disease at the Haematological Unit, Hospital de Clínicas de Porto Alegre, Brazil.
Very limited data are available in the literature to elucidate the aetiology of invasive mould infections in Latin America. Here we report that Aspergillus species caused only half of such cases in a cohort study conducted over 21 months in a university hospital in Porto Alegre, Southern Brazil. Fusarium spp. were the second most prevalent moulds (20.7%), followed by Zygomycetes (13.8%). The importance of obtaining local epidemiological data for adequately guiding empirical antifungal therapy is reinforced.
Aquino
Valério Rodrigues
VR
Microbiology Unit Section, Clinical Patology Services, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Verçosa
Emanuelle Bergonsi
EB
Falhauber
Gustavo
G
Lunardi
Luciano Werle
LW
Silla
Lucia
L
Pasqualotto
Alessandro Comarú
AC
D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D001938:Brazil; D015331:Cohort Studies; D005260:Female; D005658:Fungi / Q000145:classification* / Q000302:isolation & purification; D006785:Hospitals, University; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology* / Q000517:prevention & control; D012189:Retrospective Studies; D055815:Young Adult
D000935:Antifungal Agents; D017964:Itraconazole