title: Paradoxical brain embolism induced by Mycoplasma pneumoniae infection with deep venous thrombus.
abstract: A 21-year-old man had sudden-onset right hemiplegia and aphasia with respiratory infection. A chest X-ray disclosed consolidation in both lungs and magnetic resonance imaging showed an embolism in the left middle cerebral artery. A pelvic computed tomography scan revealed deep venous thrombus in both femoral veins. Patent foramen ovale was detected by transesophageal echocardiogram. Antibodies to M. pneumoniae were highly elevated, and hypercoagulability was subsequently detected. This case suggests that the possible pathogenic mechanism for M. pneumoniae infection-related stroke might be paradoxical brain embolism with deep venous thrombus as a consequence of the hypercoagulability related to this infection.
authors.affiliation: Department of Neurology, Nagoya University Graduate School of Medicine, Aichi.
authors.forename: Joe
authors.initials: J
authors.lastname: Senda
authors.forename: Mizuki
authors.initials: M
authors.lastname: Ito
authors.forename: Naoki
authors.initials: N
authors.lastname: Atsuta
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Watanabe
authors.forename: Naoki
authors.initials: N
authors.lastname: Hattori
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Kawai
authors.forename: Gen
authors.initials: G
authors.lastname: Sobue
mesh_terms: D019320:Embolism, Paradoxical / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis* / Q000382:microbiology; D008297:Male; D009177:Mycoplasma pneumoniae; D011019:Pneumonia, Mycoplasma / Q000150:complications / Q000175:diagnosis*; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000382:microbiology; D055815:Young Adult