title: Effects of metformin on the reproductive system of androgenized female rats.
abstract: Metformin improved the glucose rate and the homeostasis model assessment-insulin resistance (HOMA-IR) index and caused partial reversion of ovaries and uterine morphology in female rats androgenized with testosterone.
authors.affiliation: Gynecology Department, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Roberta Rassi
authors.initials: RR
authors.lastname: Mahamed
authors.forename: Carla Cristina
authors.initials: CC
authors.lastname: Maganhin
authors.forename: Ricardo Santos
authors.initials: RS
authors.lastname: Simões
authors.forename: Manuel
authors.initials: M
authors.lastname: de Jesus Simões
authors.forename: Edmund Chada
authors.initials: EC
authors.lastname: Baracat
authors.forename: José Maria
authors.initials: JM
authors.lastname: Soares
mesh_terms: D000818:Animals; D005260:Female; D007333:Insulin Resistance / Q000502:physiology; D008297:Male; D008687:Metformin / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D012098:Reproduction / Q000187:drug effects* / Q000502:physiology*; D014770:Virilism / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D008687:Metformin