title: Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review.
abstract: The effect of obesity on drug metabolism and pharmacokinetics is poorly understood, and this is particularly true in regard to contraceptive steroids. This article will review the known and theoretical physiologic and pharmacologic interactions between obesity and contraceptive steroids.
authors.affiliation: Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA. edelmana@ohsu.edu
authors.forename: Alison B
authors.initials: AB
authors.lastname: Edelman
authors.forename: Ganesh
authors.initials: G
authors.lastname: Cherala
authors.forename: Frank Z
authors.initials: FZ
authors.lastname: Stanczyk
mesh_terms: D003278:Contraceptives, Oral, Hormonal / Q000378:metabolism* / Q000493:pharmacokinetics*; D004997:Ethinyl Estradiol / Q000378:metabolism / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology; D011372:Progestins / Q000378:metabolism / Q000493:pharmacokinetics; D012869:Skin Absorption; D013256:Steroids / Q000378:metabolism / Q000493:pharmacokinetics
chemical_list: D003278:Contraceptives, Oral, Hormonal; D011372:Progestins; D013256:Steroids; D004997:Ethinyl Estradiol