title: [Observation on changes of oxygen partial pressure in the deep tissues along the large intestine meridian during acupuncture in healthy subjects].
abstract: OBJECTIVE
  To observe changes of the partial oxygen pressure in the deep tissues along the Large Intestine Meridian (LIM) during acupuncture stimulation, so as to reveal the characteristics of energy metabolism in the tissues along the LIM.
  
  
  METHODS
  Thirty-one healthy volunteer subjects were enlisted in the present study. Partial oxygen pressure (POP) in the tissues (at a depth of about 1.5 cm) of acupoints Binao (LI 14), Shouwuli (LI 13), Shousanli (LI 10), 2 non-acupoints [the midpoints between Quchi (LI 11) and LI 14, and between Yangxi (LI 5) and LI 11) of the LIM, and 10 non-meridian points, 1.5-2.0 cm lateral and medial to each of the tested points of the LIM was detected before, during and after electroacupuncture (EA) stimulation of Hegu (LI 4) by using a tissue oxygen tension needle-like sensor.
  
  
  RESULTS
  In normal condition, the POP values in the deep tissues along the LIM were significantly higher than those of the non-meridian control points on its bilateral sides. During and after EA of Hegu (LI 4), the POP levels decreased significantly in the deep tissues along the LIM in comparison with pre-EA (P < 0.01), and had no apparent changes in the non-meridian control points (P > 0.05).
  
  
  CONCLUSIONS
  POP is significantly higher in the deep tissues along the LIM of healthy subjects under normal conditions, which can be downregulated by EA of Hegu (LI 4), suggesting an increase of both the utilization rate of oxygen and energy metabolism after EA.
authors.affiliation: Key Lab of Meridian Research of Fujian Province, Fujian Academy of Chinese Medicine, Fuzhou 350003, China. mingfj@139.com
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Xiang-long
authors.initials: XL
authors.lastname: Hu
authors.forename: Zu-xing
authors.initials: ZX
authors.lastname: Wu
mesh_terms: D015670:Acupuncture Therapy; D000328:Adult; D004734:Energy Metabolism; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D016740:Meridians; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D055815:Young Adult
chemical_list: D010100:Oxygen