t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not.
Tsai
Albert G
AG
Yoda
Akinori
A
Weinstock
David M
DM
Lieber
Michael R
MR
D001483:Base Sequence; D019457:Chromosome Breakage; D056905:Chromosome Breakpoints; D002872:Chromosome Deletion; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics; D041321:Chromosomes, Human, X / Q000235:genetics; D041322:Chromosomes, Human, Y / Q000235:genetics; D018899:CpG Islands / Q000235:genetics; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D018121:Receptors, Cytokine / Q000235:genetics*; D018048:Receptors, Purinergic P2 / Q000235:genetics; D014178:Translocation, Genetic
C498762:CRLF2 protein, human; D007143:Immunoglobulin Heavy Chains; D018121:Receptors, Cytokine; D018048:Receptors, Purinergic P2