Testing pharmacogenetic indices to predict efficacy and toxicity of methotrexate monotherapy in a rheumatoid arthritis patient cohort.
Owen
S A
SA
University of Manchester, Manchester, UK.
Lunt
M
M
Hider
S L
SL
Bruce
I N
IN
Barton
A
A
Thomson
W
W
D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000235:genetics*; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D005838:Genotype; D006801:Humans; D016015:Logistic Models; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use*; D010597:Pharmacogenetics; D011237:Predictive Value of Tests; D016896:Treatment Outcome
D018501:Antirheumatic Agents; D008727:Methotrexate