[Fluorodeoxyglucose F18(FDG)-probe guided biopsy].
Although positron emission tomography-computed tomography (PET-CT) has improved the diagnosis of malignant and inflammatory abnormalities, histopathological examination is often required to supplement imaging examination in order to make a definite diagnosis. In some cases a lesion is not visible using conventional imaging techniques but is visible on a PET scan with fluorodeoxyglucose F18 (FDG). In other cases a lesion cannot be approached percutanuously because of localisation or size of the lesion. In these cases the surgeon can now perform an FDG-probe guided biopsy or resection. Using this technique the surgeon can peroperatively detect lesions that have taken up radioactive FDG - so-called FDG-avid lesions - and excise these for histopathological examination. This technique reduces the inadvertent excision of non-representative tissue and can be of value for localising FDG-avid lesions for total resections. FDG-probe guided surgery can potentially increase the sensitivity of diagnostic resections.
Hartemink
Koen J
KJ
VU Medisch Centrum, Amsterdam, Afd. Chirurgie, the Netherlands. kjhartemink@hetnet.nl
Muller
Sandra
S
Smulders
Yvo M
YM
Petrousjka van den Tol
M
M
Comans
Emile F I
EF
D001706:Biopsy / Q000295:instrumentation / Q000379:methods*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000000981:diagnostic imaging*; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18