[Contrast sensitivities of the fellow eyes in children with anisometropic and strabismic amblyopia].
OBJECTIVE
To investigate the contrast sensitivities of the fellow eyes in children with anisometropic and strabismic amblyopia.


METHODS
A retrospective study was undertaken. Medical records containing contrast sensitivity data of the fellow eyes in 107 children with anisometropic amblyopia, 110 children with strabismic amblyopia, and 30 normal children were retrieved. The contrast sensitivities of the fellow eyes in those children were compared using independent t-test and one-way analysis of variance (ANOVA) with post hoc (modified LSD) multiple comparison test.


RESULTS
Contrast sensitivity functions of the fellow eyes of children with anisometropic and strabismic amblyopia were weaker than those of the controls. The fellow eyes of children with moderate and severe strabismic amblyopia had better contrast sensitivities than those with anisometropic amblyopes. In strabismic amblyopic children, the contrast sensitivities of the fellow eyes grew with the degree of amblyopia. Occlusion therapy did not change contrast sensitivities of the fellow eyes.


CONCLUSIONS
The abnormal intraocular interactions between amblyopic and nonamblyopic "normal" eyes decrease the contrast sensitivity functions of the fellow eyes. Compared with anisometropic amblyopic children, the fellow eyes of children with moderate and severe strabismic amblyopia show more superiority in the binocular competition. Occlusion therapy may not depress contrast sensitivities of the fellow eyes in children with amblyopia.
Yang
Guo-Yuan
GY
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
Liao
Meng
M
Liu
Long-Qian
LQ
D000293:Adolescent; D000550:Amblyopia / Q000150:complications / Q000503:physiopathology*; D015858:Anisometropia / Q000150:complications* / Q000503:physiopathology; D002648:Child; D015350:Contrast Sensitivity; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013285:Strabismus / Q000150:complications* / Q000503:physiopathology