title: Study of finger print patterns in children with acute lymphoblastic leukemia.
abstract: Acute lymphoblastic leukemia (ALL) is a malignant disease of an unknown origin. The present case control study was intended to compare the finger print patterns between the children diagnosed with ALL and a control group. A total of 24 children with established ALL were included in the study. Fingerprints of the affected children were analyzed in both hands and compared with the finger print patterns of 24 age and sex matched controls. The study indicated an increase in frequency of whorls and a decreased frequency of loops in children suffering from ALL. Radial loops, double loops, central pocket loops and tented arches are found to be proportionately less frequent in cases than controls. On quantitative analysis of patterns, mean pattern intensity index (PII) was found to be higher in cases than controls; however, a significant overlapping was evident. Most of the cases (n = 10, 41.7%) had a PII of 16-20, while a PII of 11-15 is reported among most children in the control group (n = 16, 66.7%). The findings of the study are suggestive of a possible trend and an association of finger print patterns with children suffering from ALL. The present research emphasizes the significance of the application of forensic science in medicine and pathology.
authors.affiliation: Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Mario Joseph
authors.initials: MJ
authors.lastname: Bukelo
authors.forename: Tanuj
authors.initials: T
authors.lastname: Kanchan
authors.forename: B
authors.initials: B
authors.lastname: Unnikrishnan
authors.forename: T
authors.initials: T
authors.lastname: Rekha
authors.forename: B
authors.initials: B
authors.lastname: Ashoka
authors.forename: A T K
authors.initials: AT
authors.lastname: Rau
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003878:Dermatoglyphics; D005260:Female; D044707:Forensic Sciences / Q000379:methods; D006801:Humans; D008297:Male; D008403:Mass Screening; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D012307:Risk Factors