title: Isolation of N,N-dimethyl and N-methylserotonin 5-O-β-glucosides from immature Zanthoxylum piperitum seeds.
abstract: Two serotonin derivatives, N,N-dimethylserotonin 5-O-β-glucoside (1a) and N-methylserotonin 5-O-β-glucoside (1b) were isolated from immature seeds of Zanthoxylum piperitum. Their structures were determined by multi-step conversion reactions and spectroscopic analyses. Immature seeds of Z. piperitum contained extremely high levels of compounds 1a and 1b of approximately 0.29% and 0.15% (w/w), respectively.
authors.affiliation: Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Yanase
authors.forename: Masaki
authors.initials: M
authors.lastname: Ohno
authors.forename: Hironari
authors.initials: H
authors.lastname: Harakawa
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Nakatsuka
mesh_terms: D002027:Bufotenin / Q000302:isolation & purification*; D005960:Glucosides; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry*; D012701:Serotonin / Q000031:analogs & derivatives* / Q000302:isolation & purification; D012702:Serotonin Antagonists / Q000302:isolation & purification; D013057:Spectrum Analysis; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: D005960:Glucosides; D012702:Serotonin Antagonists; D002027:Bufotenin; C008494:N-methylserotonin; D012701:Serotonin