Complete enantioseparation through supramolecular complex formation between tris(1,3-diaminopropane)cobalt(III) phosphate and β-cyclodextrin, [Co(tn)3]PO4·β-CDX.
The supramolecular complex [Co(tn)(3)]PO(4)·β-CDX (tn = 1,3-diaminopropane; β-CDX = β-cyclodextrin) was prepared through β-CDX, rac-[Co(tn)(3)]Cl(3), and Na(3)PO(4) in a mole ratio of 1:2:2. After one recrystallization process, the circular dichroism spectrum confirmed that complete enantioseparation of [Co(tn)(3)]PO(4) is achieved in this system. X-ray crystal structure analysis reveals the presence of the only Λ-enantiomer in the unit cell and the head-to-head chiral discrimination structure of this system. Thus, we found that the present diastereomer formation with β-CDX affords the very convenient and effective optical resolution procedure of [Co(tn)(3)](3+).
Ohta
Natsuki
N
Institute for Higher Education Research and Practice, Osaka University, Toyonaka, Osaka 560-0043, Japan.
Fuyuhiro
Akira
A
Yamanari
Kazuaki
K