title: [Detection of the serum level of interleukin-17 and interleukin-6 in the chronic hepatitis B patients].
abstract: OBJECTIVE
  To research serum level of interleukin-17 (IL-17) associated with the progression of hepatic injury in the chronic patients with hepatitis B.
  
  
  METHODS
  The serum level of IL-17 was measured by ELISA and the serum levels of IL-6, IL-8 were measured by RIA in patient groups and healthy group, the patient groups including 42 mild patients, 37 moderate patients and 38 severe patients.
  
  
  RESULTS
  IL-17,IL-6 and IL-8 levels in patient patients were significantly higher than those in healthy people (P < 0.01). There is no significant difference among mild patients and moderate patients. Compared with mild patients and moderate patients,the cytokines lever were significantly higher in severe patients (P < 0.01).
  
  
  CONCLUSIONS
  IL-17 as a new cytokine probably play a multiple role as immune factor and inflammation element in the progression of the chronic hepatitis B disease. Maybe, it can provide a new approach to the therapy of the chronic hepatitis B.
authors.affiliation: Department of Clinical Laboratory, Zhejiang Hospital, HangZhou 310013, China.
authors.forename: Xiu-mei
authors.initials: XM
authors.lastname: Weng
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Ma
authors.forename: Huan-Qin
authors.initials: HQ
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D019694:Hepatitis B, Chronic / Q000097:blood* / Q000473:pathology; D006801:Humans; D020381:Interleukin-17 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D016209:Interleukin-8 / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D020381:Interleukin-17; D015850:Interleukin-6; D016209:Interleukin-8