Prediction of transmembrane topology and signal peptide given a protein's amino acid sequence.
Here, we describe transmembrane topology and signal peptide predictors and highlight their advantages and shortcomings. We also discuss the relation between these two types of prediction.
Käll
Lukas
L
Department of Biochemistry and Biophysics, Center for Biomembrane Research and Stockholm Bioinformatics Center, Stockholm University, Stockholm, Sweden.
D000595:Amino Acid Sequence; D002462:Cell Membrane / Q000737:chemistry*; D019295:Computational Biology / Q000379:methods*; D021382:Protein Sorting Signals; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid
D021382:Protein Sorting Signals; D011506:Proteins