title: Leuconostoc bacteremia in three patients with malignancies.
abstract: Leuconostoc is a Gram-positive coccus characterized by its resistance to glycopeptide antibiotics. Generally, this bacterium is susceptible to β-lactam antibiotics; however, here we present a leukemia patient who developed leuconostoc bacteremia during antimicrobial therapy with carbapenem. The appropriate choice of antibiotics at optimal doses enables leuconostoc infection to be overcome, even in compromised hosts. We report 3 cases of leuconostoc bacteremia: the leukemia case which was successfully treated, along with discussions of two other cases with malignancies.
authors.affiliation: Division of Cancer Medicine, Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan. ishiyama-knz@umin.ac.jp
authors.forename: Ken
authors.initials: K
authors.lastname: Ishiyama
authors.forename: Hirohito
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Senda
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yamauchi
authors.forename: Shinji
authors.initials: S
authors.lastname: Nakao
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D015780:Carbapenems / Q000627:therapeutic use; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007934:Leuconostoc / Q000254:growth & development*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems