title: Bullous exudative retinal detachment due to infiltration of leukemic cells in a child with acute lymphoblastic leukemia.
abstract: Acute lymphoblastic leukemia (ALL) is known to cause several ocular involvements, but exudative retinal detachment is a rare complication. We describe a case report of a 4-year-old boy with T cell ALL who developed bilateral exudative retinal detachment caused by leukemic infiltration in the retinas after achieving hematological remission. Intravenous steroid pulse therapy and local irradiation reversed the condition, but it recurred concurrently with disease progression after a second relapse in the bone marrow. It is suggested that ophthalmic examination is crucial for ALL patients, especially for those whose white blood cell count is very high at onset.
authors.affiliation: Department of Pediatrics, St. Luke's International Hospital, Chuo-ku, Tokyo, 104-8560, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Yoshida
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hasegawa
authors.forename: Ayako
authors.initials: A
authors.lastname: Takusagawa
authors.forename: Itaru
authors.initials: I
authors.lastname: Kato
authors.forename: Chitose
authors.initials: C
authors.lastname: Ogawa
authors.forename: Nariaki
authors.initials: N
authors.lastname: Echizen
authors.forename: Kishiko
authors.initials: K
authors.lastname: Ohkoshi
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Ryota
authors.initials: R
authors.lastname: Hosoya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Manabe
mesh_terms: D002675:Child, Preschool; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000209:etiology* / Q000473:pathology* / Q000628:therapy