Oestrogen downregulates BACE protein in human cell culture: what does this teach us about Alzheimer's disease?
Bernstein
Hans-Gert
HG
Department of Psychiatry, University of Magdeburg, Magdeburg, Germany. Hans-Gert.Bernstein@med.ovgu.de
Lendeckel
Uwe
U
Steiner
Johann
J
Bogerts
Bernhard
B
D000544:Alzheimer Disease / Q000378:metabolism* / Q000503:physiopathology; D053829:Amyloid Precursor Protein Secretases / Q000235:genetics / Q000378:metabolism*; D016282:Aspartic Acid Endopeptidases / Q000235:genetics / Q000378:metabolism*; D002478:Cells, Cultured; D015536:Down-Regulation / Q000187:drug effects* / Q000502:physiology; D004967:Estrogens / Q000494:pharmacology*; D006801:Humans; D009457:Neuroglia / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*
D004967:Estrogens; D053829:Amyloid Precursor Protein Secretases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human