Increasing incidence of inflammatory bowel disease among young men in Korea between 2003 and 2008.
OBJECTIVE
Temporal trends in incidence rates of Crohn's disease (CD) and ulcerative colitis (UC) can provide valuable clues about etiology. Korea has a draft system, and every male must fulfill his military service. However, according to military rules, patients with CD and UC are not conscripted into the army, and when the disease is diagnosed during military service, patients are relieved from military duties. Such policies provide a unique opportunity to determine the incidence of CD and UC among young men in Korea. We studied the incidence of CD and UC over time in Korea, a rapidly developing country.


METHODS
The Armed Forces Medical Command of the Republic of Korea Army provided lists of members who were relieved from military duties due to diagnoses of CD and UC between 2003 and 2008.


RESULTS
During this 6-year period, there were 96 incident cases of CD and 104 incident cases of UC. For the 6-year period, the adjusted mean annual incidence rates of CD and UC per 100,000 persons were 3.2 and 3.5, respectively. When analyzed by 2-year intervals, the mean annual incidence of CD and UC increased, from 1.8 and 1.7 per 100,000 persons in 2003-2004, to 2.7 and 3.3 per 100,000 persons in 2005-2006, and to 5.1 and 5.4 per 100,000 persons in 2007-2008, respectively.


CONCLUSIONS
Incidence of CD and UC among young men is rapidly increasing in Korea, which strongly suggests an environmental contribution to the disease.
Shin
Dong Hyuk
DH
Department of Emergency Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Sinn
Dong Hyun
DH
Kim
Young-Ho
YH
Kim
Jin Yong
JY
Chang
Dong Kyung
DK
Kim
Eun Jin
EJ
Ryu
Ho Yoel
HY
Song
Han Ul
HU
Kim
Il Young
IY
Kim
Do Hyoung
do H
Kim
Yun Young
YY
Kim
Suk Hun
SH
Seo
Yu Bin
YB
Hwang
Ki Won
KW
Kim
Jae J
JJ
D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology*; D008297:Male; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult