The BioPAX community standard for pathway data sharing.
Biological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery.
Demir
Emek
E
Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Cary
Michael P
MP
Paley
Suzanne
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Fukuda
Ken
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Lemer
Christian
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Vastrik
Imre
I
Wu
Guanming
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D'Eustachio
Peter
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Schaefer
Carl
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Luciano
Joanne
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Schacherer
Frank
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Martinez-Flores
Irma
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Hu
Zhenjun
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Jimenez-Jacinto
Veronica
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Joshi-Tope
Geeta
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Kandasamy
Kumaran
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Lopez-Fuentes
Alejandra C
AC
Mi
Huaiyu
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Pichler
Elgar
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Rodchenkov
Igor
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Splendiani
Andrea
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Tkachev
Sasha
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Zucker
Jeremy
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Gopinath
Gopal
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Rajasimha
Harsha
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Ramakrishnan
Ranjani
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Shah
Imran
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Syed
Mustafa
M
Anwar
Nadia
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Babur
Ozgün
O
Blinov
Michael
M
Brauner
Erik
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Corwin
Dan
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Donaldson
Sylva
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Gibbons
Frank
F
Goldberg
Robert
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Hornbeck
Peter
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Luna
Augustin
A
Murray-Rust
Peter
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Neumann
Eric
E
Ruebenacker
Oliver
O
Reubenacker
Oliver
O
Samwald
Matthias
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van Iersel
Martijn
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Wimalaratne
Sarala
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Allen
Keith
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Braun
Burk
B
Whirl-Carrillo
Michelle
M
Cheung
Kei-Hoi
KH
Dahlquist
Kam
K
Finney
Andrew
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Gillespie
Marc
M
Glass
Elizabeth
E
Gong
Li
L
Haw
Robin
R
Honig
Michael
M
Hubaut
Olivier
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Kane
David
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Krupa
Shiva
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Kutmon
Martina
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Leonard
Julie
J
Marks
Debbie
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Merberg
David
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Petri
Victoria
V
Pico
Alex
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Ravenscroft
Dean
D
Ren
Liya
L
Shah
Nigam
N
Sunshine
Margot
M
Tang
Rebecca
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Whaley
Ryan
R
Letovksy
Stan
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Buetow
Kenneth H
KH
Rzhetsky
Andrey
A
Schachter
Vincent
V
Sobral
Bruno S
BS
Dogrusoz
Ugur
U
McWeeney
Shannon
S
Aladjem
Mirit
M
Birney
Ewan
E
Collado-Vides
Julio
J
Goto
Susumu
S
Hucka
Michael
M
Le Novère
Nicolas
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Maltsev
Natalia
N
Pandey
Akhilesh
A
Thomas
Paul
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Wingender
Edgar
E
Karp
Peter D
PD
Sander
Chris
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Bader
Gary D
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D019295:Computational Biology / Q000379:methods* / Q000592:standards*; D019992:Databases as Topic; D033181:Information Dissemination; D053858:Metabolic Networks and Pathways; D011381:Programming Languages; D015398:Signal Transduction; D012984:Software