title: An evaluation of illness, treatment perceptions, and depression in hospital- vs. home-based dialysis modalities.
abstract: OBJECTIVE
  Depressive symptoms are common among patients with end-stage renal disease (ESRD). In order to better understand what factors influence these symptoms, we examined the impact of illness and treatment cognitions on emotional adjustment and the influence of dialysis modality (hospital- vs. home-based dialysis) on this relationship.
  
  
  METHODS
  A cross-sectional sample of 145 ESRD patients on four different dialysis modalities [hospital hemodialysis (HD), n=52; home HD, n=25; continuous ambulatory peritoneal dialysis (CAPD), n=45; automated PD (APD), n=23] completed the Illness Perceptions Questionnaire, the Illness Effects Questionnaire, the Treatment Effects Questionnaire, and the Beck Depression Inventory. Measures of ESRD severity/comorbidity and biochemistry were also collected.
  
  
  RESULTS
  Perceptions of treatment disruptiveness and attributions to poor medical care were significantly greater in CAPD. Home-based treatments were not found to confer an emotional adjustment advantage compared to hospital HD. There were marked differences across home-based modalities, with n=22 (44.4%) CAPD meeting the clinical cutoff of depression (≧16) vs. n=6 (26.1%) in APD and n=2 (8%) in home HD. After adjusting for case-mix differences, the mean levels of depressed mood remained significantly higher in CAPD patients compared to APD and home HD (P<.01). On multiple regression analysis, 42.5% of the variance in depression was explained by the End-Stage Renal Severity Index, dialysis modality, perceived treatment disruptiveness, and beliefs about illness consequences and the extent to which the illness could be controlled.
  
  
  CONCLUSIONS
  The findings suggest that the benefits of self-care are not uniformly manifested across dialysis modalities and that patients' cognitions are important determinants of depressed mood with implications for future research and clinical practice.
authors.affiliation: Department of Psychology, National University of Singapore, Singapore; Unit of Behavioural Medicine, University College London, UK.
authors.forename: Konstadina
authors.initials: K
authors.lastname: Griva
authors.forename: Andrew
authors.initials: A
authors.lastname: Davenport
authors.forename: Michael
authors.initials: M
authors.lastname: Harrison
authors.forename: Stanton
authors.initials: S
authors.lastname: Newman
mesh_terms: D000328:Adult; D001294:Attitude to Health; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010465:Perception; D012044:Regression Analysis; D006435:Renal Dialysis / Q000523:psychology*; D012648:Self Care / Q000523:psychology; D011795:Surveys and Questionnaires