Obesity-related renal damage: changing diet to avoid progression.
Obesity is increasingly recognized as a risk factor for the development of end-stage renal disease. However, few studies have investigated the influence of dietary changes on kidney function in the obese. Friedman et al. report that dietary protein intake is unlikely to fully account for elevations in glomerular filtration rate and proteinuria observed in obesity. The relationship between diet and renal hemodynamics in obesity is complex, and more studies (including ones on the effect of caloric restriction) are needed.
Praga
Manuel
M
Department of Nephrology, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain. mpragat@senefro.org
Morales
Enrique
E
D031204:Caloric Restriction; D004044:Dietary Proteins / Q000008:administration & dosage*; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007674:Kidney Diseases / Q000209:etiology / Q000503:physiopathology*; D009765:Obesity / Q000150:complications / Q000503:physiopathology*
D004044:Dietary Proteins