title: Prevalence and risk factors for mesh erosion after laparoscopic-assisted sacrocolpopexy.
abstract: OBJECTIVE
  The purpose of this study is to identify risk factors for mesh erosion in women undergoing minimally invasive sacrocolpopexy (MISC). We hypothesize that erosion is higher in subjects undergoing concomitant hysterectomy.
  
  
  METHODS
  This is a retrospective cohort study of women who underwent MISC between November 2004 and January 2009. Demographics, operative techniques, and outcomes were abstracted from medical records. Multivariable regression identified odds of erosion.
  
  
  RESULTS
  Of 188 MISC procedures 19(10%) had erosions. Erosion was higher in those with total vaginal hysterectomy (TVH) compared to both post-hysterectomy (23% vs. 5%, p = 0.003) and supracervical hysterectomy (SCH) (23% vs. 5%, p = 0.109) groups. In multivariable regression, the odds of erosion for TVH was 5.67 (95% CI: 1.88-17.10) compared to post-hysterectomy. Smoking, the use of collagen-coated mesh, transvaginal dissection, and mesh attachment transvaginally were no longer significant in the multivariable regression model.
  
  
  CONCLUSIONS
  Based on this study, surgeons should consider supracervical hysterectomy over total vaginal hysterectomy as the procedure of choice in association with MISC unless removal of the cervix is otherwise indicated.
authors.affiliation: Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California, San Diego, La Jolla, CA, USA. jstan@ucsd.edu
authors.forename: Jasmine
authors.initials: J
authors.lastname: Tan-Kim
authors.forename: Shawn A
authors.initials: SA
authors.lastname: Menefee
authors.forename: Karl M
authors.initials: KM
authors.lastname: Luber
authors.forename: Charles W
authors.initials: CW
authors.lastname: Nager
authors.forename: Emily S
authors.initials: ES
authors.lastname: Lukacz
mesh_terms: D000368:Aged; D005260:Female; D005547:Foreign Bodies / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects*; D010535:Laparoscopy; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D013526:Surgical Mesh / Q000009:adverse effects*; D014621:Vagina