Carbon-carbon bond activation by 1,1-carboboration of internal alkynes.
Internal alkynes undergo 1,1-carboboration reactions upon treatment with boranes RB(C(6)F(5))(2) (R = C(6)F(5), CH(3)) to yield trisubstituted alkenylboranes. These products can be used as substrates in Pd-catalyzed cross-coupling reactions.
Chen
Chao
C
Organisch-Chemisches Institut, Universität Münster, Corrensstrasse 40, D-48149 Münster, Germany.
Kehr
Gerald
G
Fröhlich
Roland
R
Erker
Gerhard
G
D000480:Alkynes / Q000737:chemistry*; D001880:Boranes / Q000138:chemical synthesis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
D000480:Alkynes; D001880:Boranes; D002244:Carbon