title: Effect of zinc supplementation on mycospecific immunoglobulins in tuberculosis patients.
abstract: The effect of zinc supplementation on the serum level of IgA, IgG, IgM mycospecific immunoglobulins in tuberculosis patients alongwith normal control and disease control subjects were studied. It was observed that with antituberculous drugs for one month (without zinc supplementation), the serum level of immunoglobulins in tuberculosis subjects although decreased significantly, but with zinc supplementation along with antituberculous drugs for one month the decrease in the level of immunoglobulins in serum was more significant. This may be attributed to the effect of zinc supplementation favouring the normal compartmentalisation state of iron and also to the immunomodulatory effect of zinc.
authors.affiliation: Central Laboratory, BS Medical College and Hospital, Bankura 722102.
authors.forename: Dipak Kumar
authors.initials: DK
authors.lastname: Chattopadhyay
authors.forename: Chitta Ranjan
authors.initials: CR
authors.lastname: Maity
authors.forename: Debabrata
authors.initials: D
authors.lastname: Nag
mesh_terms: D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000187:drug effects; D007074:Immunoglobulin G / Q000097:blood / Q000187:drug effects; D007075:Immunoglobulin M / Q000097:blood / Q000187:drug effects; D007136:Immunoglobulins / Q000097:blood* / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000276:immunology; D014376:Tuberculosis / Q000097:blood* / Q000188:drug therapy* / Q000276:immunology; D015032:Zinc / Q000494:pharmacology*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D015032:Zinc