title: The rationale behind novel bone grafting techniques in small animals.
abstract: Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Although allograft provides an osteoconductive matrix with some osteoinductivity, its availability is limited. To achieve optimal bone graft properties, researchers are developing new materials with the goal of designing synthetics as close to autograft as possible while still facilitating their clinical use. However, the constant evolution of internal fixation stimulates the search for growth factors and cells which could stimulate bone healing.
authors.affiliation: Department of Veterinary Clinical Medicine, University of Illinois, 1008 Hazelwood drive, Urbana, Illinois 61802, United States. ragetly2@illinois.edu
authors.forename: G R
authors.initials: GR
authors.lastname: Ragetly
authors.forename: D J
authors.initials: DJ
authors.lastname: Griffon
mesh_terms: D000818:Animals; D001847:Bone Diseases / Q000628:therapy / Q000662:veterinary*; D016025:Bone Transplantation / Q000379:methods / Q000662:veterinary*; D002371:Cat Diseases / Q000628:therapy*; D002415:Cats; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs