title: Synthesis of inherently chiral calix[4]arenes: stereocontrol through ligand choice.
abstract: Employing a chiral oxazoline as an ortholithiation directing group allows the synthesis of inherently chiral calix[4]arenes suitable for elaboration into planar chiral molecules. An important finding has been that the diastereoselectivity of the reaction can be tuned by the choice of additive. These results have bearing on the elucidation of the general mechanism of oxazoline-directed ortholithiation.
authors.affiliation: Department of Chemistry and Polymer Science, University of Stellenbosch, Matieland 7602, South Africa.
authors.forename: Simon A
authors.initials: SA
authors.lastname: Herbert
authors.forename: Gareth E
authors.initials: GE
authors.lastname: Arnott