title: Understanding the role of tumor stem cells in glioblastoma multiforme: a review article.
abstract: It has been hypothesized that cancer stem cells (CSC) may account for the pathogenesis underlying various tumors, including GBM. Markers of these CSCs can be potentially used as therapeutic targets. In this review, we discuss the most recent information regarding CSCs, their molecular biology and their potential role in GBM.
authors.affiliation: Neurosurgical Laboratory for Translational Stem Cell Research, Department of Neurosurgery, Weill Cornell Brain Tumor Center, Weill Cornell Medical College of Cornell University, 510 E 70th Street, New York, NY 10021, USA.
authors.forename: Aalya
authors.initials: A
authors.lastname: Fatoo
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Nanaszko
authors.forename: Baxter B
authors.initials: BB
authors.lastname: Allen
authors.forename: Christina L
authors.initials: CL
authors.lastname: Mok
authors.forename: Elena N
authors.initials: EN
authors.lastname: Bukanova
authors.forename: Robel
authors.initials: R
authors.lastname: Beyene
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Moliterno
authors.forename: John A
authors.initials: JA
authors.lastname: Boockvar
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D005909:Glioblastoma / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D006801:Humans; D014411:Neoplastic Stem Cells / Q000502:physiology*; D015398:Signal Transduction