title: The influence of race on the development of acute lung injury in trauma patients.
abstract: BACKGROUND
  Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality.
  
  
  METHODS
  Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center.
  
  
  RESULTS
  African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao(2)/Fio(2)) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race.
  
  
  CONCLUSIONS
  Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.
authors.affiliation: Department of Surgery, University of California, San Francisco at San Francisco, General Hospital, 94143, USA.
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Brown
authors.forename: Richard H
authors.initials: RH
authors.lastname: Kallet
authors.forename: Michael A
authors.initials: MA
authors.lastname: Matthay
authors.forename: Rochelle A
authors.initials: RA
authors.lastname: Dicker
mesh_terms: D055371:Acute Lung Injury / Q000208:ethnology* / Q000401:mortality; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D001213:Asian / Q000706:statistics & numerical data; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006786:Hospitals, Urban; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D044468:Native Hawaiian or Pacific Islander / Q000706:statistics & numerical data*; D012128:Respiratory Distress Syndrome / Q000208:ethnology* / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors; D012495:San Francisco / Q000453:epidemiology; D014193:Trauma Centers; D015599:Trauma Severity Indices; D044465:White People / Q000706:statistics & numerical data*