title: Novel isocyanide-based one-pot multicomponent syntheses of tetrahydrobenzo[b][1,4]oxazepine and malonamide derivatives.
abstract: In this work, a novel one-pot multicomponent reaction of 2-aminophenols, Meldrum's acid, and isocyanides leads to the synthesis of tetrahydrobenzo[b][1,4]oxazepine or malonamide derivatives using 1 or 2 equiv of 2-aminophenols, respectively, in good to excellent yields at ambient temperature.
authors.affiliation: Department of Chemistry, Shahid Beheshti University, G. C., P.O. Box 19396-4716, Tehran, Iran. a-shaabani@cc.sbu.ac.ir
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shaabani
authors.forename: Hamid
authors.initials: H
authors.lastname: Mofakham
authors.forename: Ali
authors.initials: A
authors.lastname: Maleki
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Hajishaabanha
mesh_terms: D000627:Aminophenols / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D003486:Cyanides / Q000737:chemistry*; D008314:Malonates / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010077:Oxazepines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000627:Aminophenols; D003486:Cyanides; D008314:Malonates; D010077:Oxazepines; C027667:2-aminophenol; C008314:malonamide