HIV-1 RNA detection in the amniotic fluid of HIV-infected pregnant women.
This study is aimed at evaluating the potential to detect human immunodeficiency virus (HIV) in amniotic fluid (AF) collected at delivery from 40 HIV-positive pregnant women. Thirty patients had a plasma viral load (VL) below 1,000 copies/mL at delivery. VL was positive in three AF samples. No significant association was found between the HIV-1 RNA in AF and the maternal plasma samples. There was no HIV vertical transmission detected.
Lobato
Ana Christina
AC
Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
Aguiar
Regina Amélia
RA
Aleixo
Agdemir Waléria
AW
Andrade
Beatriz Amélia
BA
Cavallo
Ines Katherina
IK
Kakehasi
Fabiana Maria
FM
Pinto
Jorge Andrade
JA
Melo
Victor Hugo
VH
D000653:Amniotic Fluid / Q000821:virology*; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D019562:Viral Load