Comparison of MRI and endoscopic ultrasound in the characterization of pancreatic cystic lesions.
OBJECTIVE
The purpose of this study was to compare the diagnostic performance of MRI and endoscopic ultrasound (EUS) for the characterization of cystic pancreatic lesions and prediction of malignancy.


METHODS
Fifty patients (24 women and 26 men; average age, 57 years) underwent both MRI and EUS. All pancreatic lesions (21 cystic and 29 solid lesions) were proven by histopathologic analysis. Two radiologists retrospectively examined MR images, and a single gastroenterologist reviewed EUS images. The MRI and EUS characterizations of morphologic features of the cystic lesions and predictions of malignancy were evaluated. The prediction of malignancy was done by receiver operating characteristic (ROC) curve analysis.


RESULTS
There was no difference between the ability of MRI and EUS to correctly classify lesions as cystic or solid (accuracy, 90-98% vs 88%; p > 0.05). There was no difference between the sensitivity of MRI and EUS for the characterization of septa (94.4% for MRI vs 77.8% for EUS), mural nodule (66.7-58.3% for MRI vs 58.3% for EUS), main pancreatic duct dilatation (92.9-85.7% for MRI vs 85.7% for EUS), and communication with main pancreatic duct (100% for MRI vs 88.9% for EUS). The area under ROC curve values for predicting malignancy showed no statistical significance (0.755-0.774 for MRI vs 0.769 for EUS; p > 0.894).


CONCLUSIONS
MRI and EUS are comparable in the characterization of cystic pancreatic lesions and prediction of malignancy.
Kim
Young Chul
YC
Department of Diagnostic Radiology, Research Institute of Radiological Science, Institute of Gastroenterology, Yonsei University Health System, Seodaemun-gu, Seoul 120-752, Republic of Korea.
Choi
Jin-Young
JY
Chung
Yong Eun
YE
Bang
Seungmin
S
Kim
Myeong-Jin
MJ
Park
Mi-Suk
MS
Kim
Ki Whang
KW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019160:Endosonography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010181:Pancreatic Cyst / Q000175:diagnosis*; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D055815:Young Adult