title: [Orthostatic hypotension and supine hypertension in primary autonomic failure. Pathophysiology, diagnosis and treatment].
abstract: There are three diseases classified as primary autonomic failure (PAF), multiple system atrophy, Parkinson's disease, pure autonomic failure. Compensatory mechanisms preventing from decrease in blood pressure are inefficient in PAF. Among half of the patients with PAF occur orthostatic hypotension (OH) and supine hypertension (SH), which are the cause of deterioration of life quality. The treatment is based on modification of lifestyle and pharmacotherapy. Drugs used in OH may exacerbate SH and vice versa.
authors.affiliation: Klinika Neurochirurgii, Instytut Psychiatrii i Neurologii, Warszawa. ttomasz@mp.pl
authors.forename: Tomasz
authors.initials: T
authors.lastname: Tykocki
authors.forename: Krystyna
authors.initials: K
authors.lastname: Guzek
authors.forename: Paweł
authors.initials: P
authors.lastname: Nauman
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D019578:Multiple System Atrophy / Q000150:complications; D010300:Parkinson Disease / Q000150:complications; D054970:Pure Autonomic Failure / Q000150:complications*; D011788:Quality of Life; D016683:Supine Position