title: Catalysts by the meter: rapid screening approach of N-heterocyclic carbene ligand based catalysts.
abstract: Here, we demonstrate a versatile screening platform for NHC ligand based catalysts by coating fused-silica micro capillaries with a bonded 1,3-bismesityl-2-imidazolidinylidene ligand. Such micro capillaries can be efficiently converted into (pre)-catalysts from various organometallic precursors by solid-phase chemistry techniques and can be quantitatively screened using on-column reaction chromatography.
authors.affiliation: Ruprecht-Karls-Universität Heidelberg, Organisch-Chemisches Institut, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
authors.forename: Carolin
authors.initials: C
authors.lastname: Lang
authors.forename: Ute
authors.initials: U
authors.lastname: Gärtner
authors.forename: Oliver
authors.initials: O
authors.lastname: Trapp
mesh_terms: D002384:Catalysis; D002845:Chromatography; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D057166:High-Throughput Screening Assays; D008024:Ligands; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D008024:Ligands; C030011:carbene; D012822:Silicon Dioxide; D008697:Methane