title: 'Where are we now with intravenous thrombolysis for acute ischaemic stroke'?
abstract: The publication of the updated individual patient data meta-analysis of the larger randomised trials of intravenous rt-PA for acute ischaemic stroke has re-opened the debate about how the treatment should be used in routine practice, and what information can be expected to emerge in the next 2-3 years from the ongoing trials [the largest of which is the Third International Stroke Trial (IST-3)].
authors.affiliation: University of Edinburgh, Edinburgh, UK. peter.sandercock@ed.ac.uk
authors.forename: Peter
authors.initials: P
authors.lastname: Sandercock
authors.forename: Joanna
authors.initials: J
authors.lastname: Wardlaw
authors.forename: Richard
authors.initials: R
authors.lastname: Lindley
mesh_terms: D002986:Clinical Trials as Topic; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D015201:Meta-Analysis as Topic; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator