title: Lissencephaly--not an uncommon cause of intractable seizure in children: report of 3 cases.
abstract: Lissencephaly or azyria, a rare disorder characterised by the absence of cerebral convolutions and poorly formed sylvlan fissures giving the appearance of a foetal brain with smooth cerebral surface, thickened cortical mantle and microscopic appearance ofincomplete neuronal migration. It is to consider lissencephaly in the diagnosis of developmental delay with seizure disorder as many patients may be diagnosed as cerebral palsy. Several lissencephaly syndrome have been described, Here three cases of lissencephaly with developmental delay and Intractable seizures are reported.
authors.affiliation: Department of Paediatrics, Burdwan Medical College, Burdwan 713101.
authors.forename: Taraknath
authors.initials: T
authors.lastname: Ghosh
authors.forename: Kanailai
authors.initials: K
authors.lastname: Barik
authors.forename: Kaustav
authors.initials: K
authors.lastname: Nayek
authors.forename: Mrinalkanti
authors.initials: M
authors.lastname: Ghosh
authors.forename: Asok Kumar
authors.initials: AK
authors.lastname: Datta
authors.forename: Shyamal
authors.initials: S
authors.lastname: Mitraniyogi
mesh_terms: D003937:Diagnosis, Differential; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D054082:Lissencephaly / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D012640:Seizures / Q000209:etiology*; D014057:Tomography, X-Ray Computed