Who gets cut during cell death?
The recent introduction of positional proteomics made it possible to screen for protease processing events on a proteome-wide scale. As a highly regulated and protease-dependent process, cell death has been particularly well-studied with these emerging technologies. This review provides an overview of the results obtained at the exciting interface between proteomics, protease biology and cell death.
Impens
Francis
F
Department of Medical Protein Research, VIB, B-9000 Ghent, Belgium.
Vandekerckhove
Joël
J
Gevaert
Kris
K
D000595:Amino Acid Sequence; D016923:Cell Death / Q000502:physiology*; D008969:Molecular Sequence Data; D010455:Peptides / Q000235:genetics / Q000378:metabolism; D040901:Proteomics / Q000379:methods*
D010455:Peptides