title: Accumulation of bone-seeking agent in a patient with mediastinal seminoma.
abstract: A 39-year-old man presented with substernal pain and shortness of breath. Bone scan revealed a large soft-tissue uptake in anterior chest. Subsequent computed tomography showed a large mass lesion with well demarcated margins in anterior mediastinum. Percutaneous core needle biopsy and histopathologic examination diagnosed the mediastinal seminoma. Bone scintigraphy could delineate a wide spectrum of nonosseous disorders. The recognition of extraskeletal uptake of bone-seeking agent can enhance the diagnostic value of bone scintigraphy.
authors.affiliation: Department of Nuclear Medicine, Wonkwang University School of Medicine, Iksan, Jeollabuk-do, Korea. akaxan@nate.com
authors.forename: Dae-Weung
authors.initials: DW
authors.lastname: Kim
authors.forename: Sang-Ah
authors.initials: SA
authors.lastname: Jung
authors.forename: Soon-Ah
authors.initials: SA
authors.lastname: Park
authors.forename: Chang-Guhn
authors.initials: CG
authors.lastname: Kim
mesh_terms: D000328:Adult; D001692:Biological Transport; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism*; D011877:Radionuclide Imaging; D018239:Seminoma / Q000000981:diagnostic imaging / Q000378:metabolism*