title: Cigarette smoking induces vascular proliferative disease through the activation of Egr-1.
authors.forename: Noboru
authors.initials: N
authors.lastname: Fukuda
mesh_terms: D000284:Administration, Oral; D000818:Animals; D050197:Atherosclerosis / Q000209:etiology* / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control; D020013:Calcium Signaling / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects*; D051766:Early Growth Response Protein 1 / Q000235:genetics / Q000378:metabolism*; D004789:Enzyme Activation; D006801:Humans; D007083:Iliac Artery / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D019950:Mitogen-Activated Protein Kinase 1 / Q000037:antagonists & inhibitors / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000037:antagonists & inhibitors / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000293:injuries / Q000378:metabolism / Q000473:pathology; D009538:Nicotine / Q000008:administration & dosage / Q000009:adverse effects; D018722:Nicotinic Agonists / Q000008:administration & dosage / Q000009:adverse effects; D010766:Phosphorylation; D051381:Rats; D011978:Receptors, Nicotinic / Q000187:drug effects / Q000378:metabolism; D012907:Smoking / Q000009:adverse effects*; D017539:Tunica Intima / Q000187:drug effects* / Q000293:injuries / Q000378:metabolism / Q000473:pathology
chemical_list: D051766:Early Growth Response Protein 1; C486110:Egr1 protein, rat; D018722:Nicotinic Agonists; D011978:Receptors, Nicotinic; D009538:Nicotine; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3