Organocatalytic strategies for the asymmetric functionalization of indoles.
The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009 (127 references).
Bartoli
Giuseppe
G
Università di Bologna, Dipartimento di Chimica Organica A. Mangini, viale Risorgimento 4, I-40136 Bologna, Italy. giuseppe.bartoli@unibo.it
Bencivenni
Giorgio
G
Dalpozzo
Renato
R
D000478:Alkylation; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D007211:Indoles; D009942:Organometallic Compounds