The future of women's contraception: stakes and modalities.
The two main contraceptive methods are the combined pill and the intrauterine device. In several countries, sterilization is a commonly used alternative. The current goals of contraception remain to achieve effective, accessible, reversible, and well-tolerated birth control for everyone. Despite progress, these goals have not been reached. To achieve these goals, it is mandatory to create new hormonal combinations and to discover new contraceptive targets. Recent innovations associate the development of new progestogens, selective progesterone receptor modulators, and the creation of new contraceptive combinations. Other innovations involve the use of natural estrogens but also optimizing existing treatment regimens and doses, as well as the development of new methods of emergency contraception. Finally, a major step will be to invent an efficient contraceptive that carries the lowest possible risk associated with methods protecting against sexually transmitted diseases. In the future, in relation to progress in the fields of genomics, proteomics, and immunology, new methods of contraception will be developed. These methods will be more targeted and will eventually be nonhormonal and independent of sexual activity.
Hugon-Rodin
Justine
J
Endocrinology, Hospital Saint Antoine AP-HP, Paris, France.
Chabbert-Buffet
Nathalie
N
Bouchard
Philippe
P
D000028:Abortion, Induced / Q000706:statistics & numerical data; D003267:Contraception / Q000009:adverse effects / Q000379:methods* / Q000639:trends*; D003271:Contraceptive Agents, Female / Q000627:therapeutic use; D004997:Ethinyl Estradiol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000706:statistics & numerical data; D011247:Pregnancy; D011275:Pregnancy, Unwanted; D016896:Treatment Outcome
D003271:Contraceptive Agents, Female; D004997:Ethinyl Estradiol