Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations.
A total of 149 unrelated and healthy individuals comprising: Tunisian Berbers, Tunisians with Andalusian origin and Libyans were typed with the SNPforID 34-plex ancestry informative marker (AIM) SNP panel. Results of 31 of the 34 SNPs are presented and no deviations from Hardy-Weinberg equilibrium were observed after Bonferroni correction (p=0.00161) except rs722098 (p=0.0000). Comparisons of allele frequencies showed high divergence values between North Africans and Europeans (δ>30%) in markers: rs4540055 (allele A) and rs16891982. Our study adds data that can be used as training set genotypes for future ancestry investigations in forensic cases and suggests these AIM-SNPs can successfully differentiate North Africans and Mediterranean Europeans.
Khodjet-el-Khil
H
H
Laboratory of Genetics, Immunology and Human Pathology, Faculty of Sciences of Tunis, El Manar University, Manar I, 1060 Tunis, Tunisia. housseinkek@yahoo.fr
Fadhlaoui-Zid
K
K
Cherni
L
L
Phillips
C
C
Fondevila
M
M
Carracedo
A
A
Ben Ammar-Elgaaied
A
A
D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008002:Libya; D020641:Polymorphism, Single Nucleotide; D014416:Tunisia