When chiral product and catalyst are the same: discovery of asymmetric organoautocatalysis.
The process of asymmetric organoautocatalysis appears to be a natural extension to asymmetric organocatalysis, and holds implications for models on the origin of biological homochirality. The discovery of asymmetric organoautocatalysis (i.e. the process in which the chiral product of a purely organic reaction acts as an organocatalyst for its own formation under conservation of its absolute configuration) and more recent reports on related systems are discussed in this review.
Tsogoeva
Svetlana B
SB
Department of Chemistry and Pharmacy, Chair of Organic Chemistry I, University of Erlangen-Nuremberg, Henkestrasse 42, 91054 Erlangen, Germany. tsogoeva@chemie.uni-erlangen.de
D002384:Catalysis; D009930:Organic Chemicals / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
D009930:Organic Chemicals