Racial disparities in diarrhea-associated hospitalizations among children in five US States, before and after introduction of rotavirus vaccine.
Racial differences in diarrheal disease have not been systematically examined, and the impact of rotavirus vaccine on these differences has not been assessed. We compared diarrhea-associated hospitalizations by race/ethnicity among children <5 years pre- (2000-2006) and post- (2007 and 2008) rotavirus vaccine introduction in five US states. Pre-vaccine hospitalization rates were greater among whites versus blacks and Hispanics. However, black (versus non-black) infants <6 months and white (versus non-white) children ≥ 1 year had higher rates. In 2008, racial disparities for children 12-35 months resolved, but higher hospitalization rates among black infants <6 months persisted, highlighting the need for timely vaccination.
Yen
Catherine
C
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. cyen@cdc.gov
Steiner
Claudia A
CA
Barrett
Marguerite
M
Curns
Aaron T
AT
Hunter
Katherine
K
Wilson
Emily
E
Parashar
Umesh D
UD
D001741:Black or African American / Q000706:statistics & numerical data; D002675:Child, Preschool; D003967:Diarrhea / Q000517:prevention & control* / Q000821:virology; D054624:Health Status Disparities; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D012400:Rotavirus Infections / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage*; D014481:United States; D014611:Vaccination / Q000706:statistics & numerical data; D044465:White People / Q000706:statistics & numerical data
D022243:Rotavirus Vaccines