title: The IT-infrastructure of a biobank for an academic medical center.
abstract: For high quality research in biomedicine an operable biobank is essential. In order to make optimal use of the material and the huge amount of data a sustainable IT-infrastructure is indispensable. Therefore, we developed a concept for the IT-infrastructure of a biobank for an academic medical center. The conclusions for this concept are deduced from our experience with the biobank and IT-infrastructure of a clinical research unit. Our results indicate that the IT-infrastructure plays a pivotal role in successfully establishing a biobank. Several aspects of the IT-infrastructure are similarly found in other areas as, e.g. data protection and storage and quality management. Finally, we conclude that although a research database is not required for operating a biobank, the need for it will definitely emerge, especially with regard to personalized medicine and high-throughput gene expression analysis.
authors.affiliation: University Medical Center, Goettingen, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Dangl
authors.forename: Sara Y
authors.initials: SY
authors.lastname: Demiroglu
authors.forename: Jochen
authors.initials: J
authors.lastname: Gaedcke
authors.forename: Krister
authors.initials: K
authors.lastname: Helbing
authors.forename: Peter
authors.initials: P
authors.lastname: Jo
authors.forename: Fabian
authors.initials: F
authors.lastname: Rakebrandt
authors.forename: Otto
authors.initials: O
authors.lastname: Rienhoff
authors.forename: Ulrich
authors.initials: U
authors.lastname: Sax
mesh_terms: D000046:Academic Medical Centers / Q000458:organization & administration*; D018070:Biological Specimen Banks / Q000458:organization & administration*; D016494:Computer Security; D001330:Electronic Data Processing; D019451:Information Management; D057285:Precision Medicine