title: Audiologic evaluation in patients with acquired hypothyroidism.
abstract: Hearing loss in hypothyroidism has been reported by many authors but its pathophysiology is unclear.
  
  
  OBJECTIVE
  to study the audiological evaluation of patients with acquired hypothyroidism.
  
  
  METHODS
  two groups were included: a hypothyroidism group (HG, n-30), and a control group (CG, n-30). Parameters studied: gender, time of hypothyroidism, comorbidities, cochleovestibular symptoms, biochemistry and hormonal exams (TSH, T4), tonal audiometry, TOAEs and BERA.
  
  
  RESULTS
  all participants were women, 70% of the HG had Hashimoto thyroiditis, 60% of the HG had had the diagnostic of the hypothyroidism for at least five years. Depression and hypertension were frequent in HG. All HG patients had altered TSH values and 50% had diminished T4 values. Sensorineural hearing loss was detected in 22 ears from the HG and in seven from the CG. BERA was normal in the CG and altered in 10 ears from the HG, showing L-V increase. TOAEs were absent in 12 ears from the HG and in four from the CG.
  
  
  CONCLUSIONS
  HG patients had more cochleovestibular symptoms, higher audiometric thresholds, increase in L-V in the BERA and absence or reduction in TOAEs amplitudes. Such alterations were not associated with THS and free T4 levels.
authors.affiliation: General Basis of Surgery, Medical School, UNESP, Botucatu.
authors.forename: Karlos Thiago Pinheiro dos
authors.initials: KT
authors.lastname: Santos
authors.forename: Norimar Hernandes
authors.initials: NH
authors.lastname: Dias
authors.forename: Gláucia Maria Ferreira da Silva
authors.initials: GM
authors.lastname: Mazeto
authors.forename: Lidia Raquel de
authors.initials: LR
authors.lastname: Carvalho
authors.forename: Renan Luis
authors.initials: RL
authors.lastname: Lapate
authors.forename: Regina Helena Garcia
authors.initials: RH
authors.lastname: Martins
mesh_terms: D001301:Audiometry, Pure-Tone; D015415:Biomarkers / Q000097:blood; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D012720:Severity of Illness Index; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
chemical_list: D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine