title: Nonsurgical repair of a pseudoaneurysm in a cynomolgus macaque (Macaca fascicularis).
abstract: A cynomolgus macaque presented with an ecchymotic and edematous left leg approximately 1 wk after a blood sample had been collected from the left femoral vein. Ecchymosis was noted in the femoral triangle, prepuce, and scrotum. The animal was not febrile or exhibiting signs of pain or distress. Duplex Doppler ultrasound imaging was used to evaluate the area. An arteriovenous fistula between the femoral artery and vein, accompanied by a pseudoaneurysm arising from the femoral artery, was identified. Various invasive and noninvasive treatment options for the pseudoaneurysm, including surgical repair, thrombin injection, stent placement, and ultrasound-guided compression repair (UGCR), were considered. UGCR was chosen as the first option for treatment. After a total of 20 min of UGCR at the neck of the pseudoaneurysm, complete thrombosis was achieved. Subsequent imaging of the lesion revealed resolution of the pseudoaneurysm. Because of the risks involved with invasive management techniques for this vascular lesion, UGCR is a valuable noninvasive treatment option for the repair of pseudoaneurysms.
authors.affiliation: Office of Animal Resources, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. judith.daviau@jefferson.edu
authors.forename: Judith S
authors.initials: JS
authors.lastname: Daviau
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Merton
mesh_terms: D017541:Aneurysm, False / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D000818:Animals; D005263:Femoral Artery / Q000473:pathology*; D008252:Macaca fascicularis; D008297:Male; D014464:Ultrasonic Therapy / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000295:instrumentation / Q000379:methods