Metal-free deprotonative functionalization of heteroaromatics using organic superbase catalyst.
Metal-free deprotonative functionalization of heteroaromatic compounds was achieved using an organic superbase catalyst; an organosilicon additive such as trimethylsilylpropyne was employed for activating the catalytic cycle of 1,2-addition to carbonyl compounds.
Hirono
Yutaro
Y
Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki Aza Aoba 6-3, Aoba-ku, Sendai 980-8578, Japan.
Kobayashi
Koji
K
Yonemoto
Misato
M
Kondo
Yoshinori
Y
D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry*; D011522:Protons
D006571:Heterocyclic Compounds; D017646:Organosilicon Compounds; D011522:Protons