Subconjunctival masses associated with central nervous system rosai-dorfman disease.
OBJECTIVE
To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy.


METHODS
Case report.


RESULTS
A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease.


CONCLUSIONS
The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
Cavuoto
Kara
K
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. kcavuoto@med.miami.edu
Galor
Anat
A
Dubovy
Sander R
SR
Gregori
Ninel
N
McCarthy
Micheline
M
D000284:Administration, Oral; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003229:Conjunctival Diseases / Q000473:pathology* / Q000601:surgery; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology; D013256:Steroids / Q000008:administration & dosage
D013256:Steroids