title: The first outbreak of brucellosis in the region of Sabac.
abstract: OBJECTIVE
  In Serbia brucellosis is a primary disease of the animals in the southern parts of the country. The aim of this study was to describe the first outbreak of human and animal brucellosis in the region of Sabac, Serbia.
  
  
  METHODS
  An epidemiological investigation was conducted to identify a source of outbreak and the ways of transmission of brucellosis infection in human population. A descriptive and analytical epidemiological methods (cohort study) were used. Additional data included monthly reports of the infectious diseases from the Institutes of Public Health and data from the Veterinary Specialistic Institute in Sabac. The serological tests for human brucellosis cases were performed in the Laboratory of the Military Medical Academy; laboratory confirmation of animal brucellosis cases was obtained from the reference laboratory of the Faculty of Veterinary Medicine, Belgrade.
  
  
  RESULTS
  Twelve cases of brucellosis were recorded from February 9 to September 1, 2004. Total attack rate was 8.1% (7.5% of males, 14.2% of females). Relative risk (RR) of milk consumption was 8.9 (95% confidence interval: 1.63-13.38), and RR for direct contact with animals was 14 (95% confidence interval: 3.5-55.6). The prevalence of seropositive animals in 33 villages of the Macva region accounted for 0.8%. Regarding animal species, sheep were predominant--264 (95.7%). Out of a total number of seropositive animals, ELISA results were positive in 228 (88.7%) of them.
  
  
  CONCLUSIONS
  As contact epidemics generally last longer, it is probable that the implemented measures of outbreak control did reduce the length of their duration.
authors.affiliation: School of Medicine, Institute of Epidemiology, Belgrade, Serbia. lj.denic@gmail.com
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Marković-Denić
authors.forename: Vesna Skodrić
authors.initials: VS
authors.lastname: Trifunović
authors.forename: Vladimir
authors.initials: V
authors.lastname: Zugić
authors.forename: Dragana
authors.initials: D
authors.lastname: Radojić
authors.forename: Goran
authors.initials: G
authors.lastname: Stevanović
mesh_terms: D000328:Adult; D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology; D002006:Brucellosis / Q000453:epidemiology* / Q000635:transmission; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055771:Serbia / Q000453:epidemiology; D055815:Young Adult; D015047:Zoonoses / Q000453:epidemiology*