title: The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selectivity.
authors.affiliation: The Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, UK. pr340@wbic.cam.ac.uk
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Riss
authors.forename: Markus
authors.initials: M
authors.lastname: Piel
authors.forename: Vanessa
authors.initials: V
authors.lastname: Bockhart
authors.forename: Nicole
authors.initials: N
authors.lastname: Bausbacher
authors.forename: Hans-Georg
authors.initials: HG
authors.lastname: Buchholz
authors.forename: Hartmut
authors.initials: H
authors.lastname: Lueddens
authors.forename: Frank
authors.initials: F
authors.lastname: Roesch
mesh_terms: D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism; D002250:Carbon Radioisotopes / Q000737:chemistry; D003042:Cocaine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D050483:Dopamine Plasma Membrane Transport Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D005462:Fluorine Radioisotopes / Q000737:chemistry; D008024:Ligands; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D015306:Biogenic Monoamines; D002250:Carbon Radioisotopes; D003287:Contrast Media; D050483:Dopamine Plasma Membrane Transport Proteins; D005462:Fluorine Radioisotopes; D008024:Ligands; D019275:Radiopharmaceuticals; C555044:methyl-8-((2-(fluoromethyl)cyclopropyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylate; D003042:Cocaine