title: Rhabdomyosarcoma of the head and neck: 24 cases and literature review.
abstract: Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissues, more common in childhood, mainly located in the head and neck. It presents varied clinical and biological behavior and requires individualized management.
  
  
  OBJECTIVE
  To describe information on patients with head and neck RMS diagnosed and treated in a hospital, and to compare them to results in the literature.
  
  
  METHODS
  Descriptive and retrospective.
  
  
  METHODS
  A retrospective analysis of data from 24 patients with head and neck rhabdomyosarcoma diagnosed and treated in a hospital from 1994 to 2008.
  
  
  RESULTS
  The mean age was 7.79 years. According to gender, 54.17 % were males and 45.83 % were female. All patients underwent chemotherapy (CT), 62.5% of them also underwent radiotherapy (RT) and 16.67% were submitted to surgery. Of the 24 patients, 8 (33.3%) died, 6 (25%) were found free of neoplasia and 2 (8.3%) experienced tumor recurrence.
  
  
  CONCLUSIONS
  The RMS of the head and neck often presents with nonspecific symptoms. Individualized multimodal therapy should be performed for these patients, including surgery, chemotherapy and radiotherapy.
authors.affiliation: Otorhinolaryngological Unit, Clinical Hospital, Medical School, São Paulo University.
authors.forename: Giovana
authors.initials: G
authors.lastname: Moretti
authors.forename: Ricardo
authors.initials: R
authors.lastname: Guimarães
authors.forename: Karisa Martins de
authors.initials: KM
authors.lastname: Oliveira
authors.forename: Fernanda
authors.initials: F
authors.lastname: Sanjar
authors.forename: Richard Louis
authors.initials: RL
authors.lastname: Voegels
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D018572:Disease-Free Survival; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D055815:Young Adult