title: Experimental model of isolated lung perfusion in rats: technique and application in lung preservation studies.
abstract: Small animal models are particularly suitable for lung preservation studies, because they are simple and cost-effective. This brief communication focuses on the technical description of an ex vivo lung perfusion model in rats by means of a commercially available apparatus, which was the first to be installed in a thoracic surgery research laboratory in Brazil. The model and its preparation, together with its applications for lung preservation studies, are described in detail. All technical details can also be seen in a video posted on the website of the Brazilian Journal of Pulmonology.
authors.affiliation: Departamento de Cardiopneumologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil. paulopego@incor.usp.br
authors.forename: Paulo Manuel
authors.initials: PM
authors.lastname: Pêgo-Fernandes
authors.forename: Eduardo de Campos
authors.initials: Ede C
authors.lastname: Werebe
authors.forename: Paulo Francisco Guerreiro
authors.initials: PF
authors.lastname: Cardoso
authors.forename: Rogério
authors.initials: R
authors.lastname: Pazetti
authors.forename: Karina Andrighetti de
authors.initials: KA
authors.lastname: Oliveira
authors.forename: Paula Roberta Otaviano
authors.initials: PR
authors.lastname: Soares
authors.forename: Fabio Biscegli
authors.initials: FB
authors.lastname: Jatene
mesh_terms: D000818:Animals; D008168:Lung; D016040:Lung Transplantation; D008297:Male; D009926:Organ Preservation / Q000379:methods*; D010477:Perfusion / Q000379:methods*; D011897:Random Allocation; D051381:Rats