title: Impact of duct-to-mucosa pancreaticojejunostomy with external drainage of the pancreatic duct after pancreaticoduodenectomy.
abstract: BACKGROUND
  A variety of different techniques are established for the management of the pancreatic remnant after partial pancreaticoduodenectomy. Although pancreaticojejunostomy is one of the most favored methods, technical details are still under discussion. We report about a series of duct-to-mucosa pancreaticojejunostomies with total external drainage of the pancreatic duct.
  
  
  METHODS
  Between 1998 and 2007 257 patients underwent surgical therapy for malignant disease of the pancreas and the periampullary region and for chronic pancreatitis. Of these, 153 partial pancreaticoduodenectomies (85 pylorus preserving resections and 68 Whipple's procedures) were performed. In all of these cases, the pancreatic remnant was drained by a duct-to-mucosa pancreaticojejunostomy with external drainage of the pancreatic duct. Presence of postoperative pancreatic fistula (PPF) was defined according to the International Study Group on Pancreatic Fistula (ISGPF).
  
  
  RESULTS
  Postoperative mortality was 1.9%. The incidence of postoperative pancreatic fistula (PPF) was 19.6% according to the ISGPF criteria. Only one patient required re-laparotomy for complications caused by PPF. Patients with PPF had a significantly longer operation time (7.3 h versus 6.6 h; P=0.041). Incidence of PPF was not influenced by histology. In all cases the fistulas resolved under conservative treatment.
  
  
  CONCLUSIONS
  Duct-to-mucosa PJ with external drainage is a safe procedure to enteralize the pancreatic stump after partial pancreaticoduodenectomy.
authors.affiliation: Department of General, Visceral and Cancer Surgery, University of Cologne, Germany. Klaus.Prenzel@uk-koeln.de
authors.forename: Klaus L
authors.initials: KL
authors.lastname: Prenzel
authors.forename: Arnulf H
authors.initials: AH
authors.lastname: Hölscher
authors.forename: Inga
authors.initials: I
authors.lastname: Grabolle
authors.forename: Ulrich
authors.initials: U
authors.lastname: Fetzner
authors.forename: Robert
authors.initials: R
authors.lastname: Kleinert
authors.forename: Christian A
authors.initials: CA
authors.lastname: Gutschow
authors.forename: Dirk L
authors.initials: DL
authors.lastname: Stippel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater / Q000601:surgery; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D010193:Pancreaticojejunostomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D050500:Pancreatitis, Chronic / Q000401:mortality / Q000601:surgery; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control*; D012307:Risk Factors