Flavin-cyclodextrin conjugates as catalysts of enantioselective sulfoxidations with hydrogen peroxide in aqueous media.
β-Cyclodextrin-flavin conjugates are highly efficient catalysts for the sulfoxidation of methyl phenyl sulfides with hydrogen peroxide in neat aqueous media operating at loadings down to 0.2 mol% and allowing for enantioselectivities up to 80% ee.
Mojr
Viktor
V
Department of Organic Chemistry, Institute of Chemical Technology, Prague, Technická 5, Prague 6, Czech Republic.
Herzig
Vladimír
V
Buděšínský
Miloš
M
Cibulka
Radek
R
Kraus
Tomáš
T
D002384:Catalysis; D005415:Flavins / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013440:Sulfides / Q000737:chemistry*; D014867:Water / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry*
D005415:Flavins; D013440:Sulfides; D047392:beta-Cyclodextrins; D014867:Water; C093850:methylphenylsulfide; D006861:Hydrogen Peroxide; C031215:betadex