Maternal and fetal leptin and ghrelin levels: relationship with fetal growth.
OBJECTIVE
In our study, we investigated the influence of plasma levels ghrelin, leptin and other metabolic hormones (ILGF-1 and ILGF-2) in pregnants in regulating fetal body weight and mode of delivery.


METHODS
A total of 36 appropriately healthy pregnants 19-36-year-old were involved in the study. Demographic characteristics, serum ghrelin, leptin, IGF-1 and IGF-2 levels of the pregnants were studied.


RESULTS
Plasma ghrelin and leptin levels did not differ significantly among trimesters and delivery, in contrast to IGF-I and IGF-II concentrations were significantly higher in the first half of the pregnancy (P < 0.05). Serum leptin was significantly associated with mode of delivery (r = 0.231; P = 0.008), BMI (r = 0.462; P = 0.004).


CONCLUSIONS
Metabolic factors are associated with fetal growth, but in AGA babies, there were no differences between any parameter and clinical factor.
Saylan
Filiz
F
Erzincan Government Hospital, Erzincan, Turkey.
Köken
Gülengül
G
Cosar
Emine
E
Köken
Tülay
T
Saylan
Arif
A
Arıöz
Dağıstan Tolga
DT
Sahin
Figen
F
Köken
Reşit
R
Yılmazer
Mehmet
M
D000328:Adult; D001724:Birth Weight; D015992:Body Mass Index; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D047109:Fetal Development / Q000502:physiology*; D054439:Ghrelin / Q000097:blood*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism*; D020738:Leptin / Q000097:blood*; D036801:Parturition / Q000097:blood; D011247:Pregnancy / Q000097:blood*; D011264:Pregnancy Trimesters / Q000097:blood; D055815:Young Adult
D054439:Ghrelin; D020738:Leptin; D007334:Insulin-Like Growth Factor I; D007335:Insulin-Like Growth Factor II