Novel and efficient one-step parallel synthesis of dibenzopyranones via Suzuki-Miyaura cross coupling.
Microwave-promoted novel and efficient one-step parallel synthesis of dibenzopyranones and heterocyclic analogues from bromo arylcarboxylates and o-hydroxyarylboronic acids via Suzuki-Miyaura cross coupling reaction is described. Spontaneous lactonization gave dibenzopyranones and heterocyclic analogues bearing electron-donating and -withdrawing groups on both aromatic rings in good to excellent yields.
Vishnumurthy
Kodumuru
K
Center for Drug Discovery, 360 Huntington Avenue, 116 Mugar Hall, Boston, Massachusetts 02115-5000, USA. kvishnumurthy@hotmail.com
Makriyannis
Alexandros
A
D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D013237:Stereoisomerism
D001578:Benzopyrans; D006571:Heterocyclic Compounds