title: Carboxymethylated cyclosophoraose as a novel chiral additive for the stereoisomeric separation of some flavonoids by capillary electrophoresis.
abstract: A carboxymethylated cyclosophoraose (CM-Cys) was synthesized by the chemical modification of neutral Cys, which was isolated from Rhizobium trifolii TA-1. CM-Cys was successfully applied as a novel chiral selector for the separation of some flavonoids including catechin, 3,5,7,3',4'-pentahydroxyflavanone, hesperidin, hesperetin, isosakuranetin, naringenin, naringin, and eriodictyol. The effects of pH, chiral additive concentration, and temperature on resolution and migration time were also studied.
authors.affiliation: Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, 1 Hwayang-dong Gwangjin-gu, Seoul 143-701, South Korea.
authors.forename: Yukyoung
authors.initials: Y
authors.lastname: Jeon
authors.forename: Chanho
authors.initials: C
authors.lastname: Kwon
authors.forename: Eunae
authors.initials: E
authors.lastname: Cho
authors.forename: Seunho
authors.initials: S
authors.lastname: Jung
mesh_terms: D019075:Electrophoresis, Capillary; D005419:Flavonoids / Q000302:isolation & purification*; D005936:Glucans / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D005419:Flavonoids; D005936:Glucans; C003328:sophorose