title: Dysphagia in Huntington's disease: a review.
abstract: Huntington's disease (HD) is a progressive neurodegenerative autosomal dominant disease characterized by disturbed movements and behavior and cognitive decline. The motor disturbances are both choreiform and hypokinetic. As a result of the combination of these signs, it is known that many patients with HD suffer from dysphagia. Little is known about the frequency and the characteristics of dysphagia in HD. Well-balanced strategies for treatment and prevention of dysphagia in HD are lacking. Therefore, we have performed a detailed survey of the literature. We found that the patient groups studied were heterogeneous and the methods used were highly variable, and no balanced advice for prevention and treatment was systematically proven.
authors.affiliation: Department of Neurology, Leiden University Medical Centre (LUMC), Albinusdreef 2, P.O. Box 9600, 2300 RC Leiden, The Netherlands. w.a.heemskerk@lumc.nl
authors.forename: Anne-Wil
authors.initials: AW
authors.lastname: Heemskerk
authors.forename: Raymond A C
authors.initials: RA
authors.lastname: Roos
mesh_terms: D003679:Deglutition; D003680:Deglutition Disorders / Q000175:diagnosis / Q000209:etiology*; D018450:Disease Progression; D005471:Fluoroscopy / Q000295:instrumentation / Q000379:methods; D006801:Humans; D006816:Huntington Disease / Q000150:complications* / Q000235:genetics; D012307:Risk Factors