Self-assembled encapsulation systems with pH tunable release property based on reversible covalent bond.
Dynamic diblock polymer PS-r-PEG formed via reversible acylhydrazone connection can be used to construct a pH-responsive self-assembled encapsulation system with high stability and sustained-release property, which shows potential in drug delivery.
He
Lin
L
Instrumental Analysis Center, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China. lhe@sjtu.edu.cn
Jiang
Yi
Y
Tu
Chunlai
C
Li
Guolin
G
Zhu
Bangshang
B
Jin
Chengyu
C
Zhu
Qi
Q
Yan
Deyue
D
Zhu
Xinyuan
X
D003692:Delayed-Action Preparations / Q000138:chemical synthesis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D011137:Polystyrenes / Q000138:chemical synthesis / Q000737:chemistry*; D011166:Porphyrins / Q000008:administration & dosage
D003692:Delayed-Action Preparations; D011137:Polystyrenes; D011166:Porphyrins; C103390:polyethylene glycol-polystyrene; D011092:Polyethylene Glycols