Bacteriophage PhiX174's ecological niche and the flexibility of its Escherichia coli lipopolysaccharide receptor.
To determine bacteriophage PhiX174's ecological niche, 783 Escherichia coli isolates were screened for susceptibility. Sensitive strains are diverse regarding their phylogenies and core lipopolysaccharides (LPS), but all have rough phenotypes. Further analysis of E. coli K-12 LPS mutants revealed that PhiX174 can use a wide diversity of LPS structures to initiate its infectious process.
Michel
Alix
A
INSERM U722 and Université Paris 7, Faculté de Médecine, Site Xavier Bichat, 16 Rue Henri Huchard, 75018 Paris, France.
Clermont
Olivier
O
Denamur
Erick
E
Tenaillon
Olivier
O
D010584:Bacteriophage phi X 174 / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D004463:Ecology; D004926:Escherichia coli / Q000378:metabolism / Q000821:virology*; D048168:Escherichia coli K12 / Q000378:metabolism / Q000821:virology; D008070:Lipopolysaccharides / Q000235:genetics / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D010802:Phylogeny
D008070:Lipopolysaccharides