Protracted benefit from paradoxical kinesia in typical and atypical parkinsonisms.
Paradoxical kinesia (PK) is the sudden resolution of a previously stabilized akinesia in an advanced idiopathic Parkinson's disease (IPD) patient facing an immediate threat. We are reporting the effect of PK, as a consequence of a life threatening event (earthquake), in a group of 14 patients with parkinsonism and dementia in Hoehn/Yahr (H/Y) stage 3-5. All the patients presented an extraordinary motor response during the earthquake that has recently stricken the Italian city of L'Aquila. All of them were able to safely escape unaided and, in some cases, to assist their families, despite they suffered before from severe night time akinesia and gait difficulties with postural instability requiring assistance. In five patients, the improvement of motor disabilities, particularly of freezing, lasted for 2-5 months.
Bonanni
L
L
Department of Neuroscience and Imaging, University G.D'Annunzio of Chieti-Pescara, Chieti-Pescara, Italy.
Thomas
A
A
Anzellotti
F
F
Monaco
D
D
Ciccocioppo
F
F
Varanese
S
S
Bifolchetti
S
S
D'Amico
M C
MC
Di Iorio
A
A
Onofrj
M
M
D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm / Q000502:physiology; D055866:Earthquakes; D005239:Fear / Q000502:physiology; D005260:Female; D006801:Humans; D018476:Hypokinesia / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D020734:Parkinsonian Disorders / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D020127:Recovery of Function / Q000502:physiology*; D012075:Remission, Spontaneous; D013315:Stress, Psychological / Q000503:physiopathology*