title: Synthesis and antifungal activity of benzofuran-5-ols.
abstract: Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.
authors.affiliation: College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea. ckryu@ewha.ac.kr
authors.forename: Chung-Kyu
authors.initials: CK
authors.lastname: Ryu
authors.forename: Ae Li
authors.initials: AL
authors.lastname: Song
authors.forename: Jung Yoon
authors.initials: JY
authors.lastname: Lee
authors.forename: Jung An
authors.initials: JA
authors.lastname: Hong
authors.forename: Joo Hee
authors.initials: JH
authors.lastname: Yoon
authors.forename: Aram
authors.initials: A
authors.lastname: Kim
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects; D003455:Cryptococcus neoformans / Q000187:drug effects; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents; D001572:Benzofurans