title: Caries-preventive efficacy and retention of a resin-modified glass ionomer cement and a resin-based fissure sealant: a 3-year split-mouth randomised clinical trial.
abstract: OBJECTIVE
  This prospective clinical trial compared the retention rate and caries-preventive efficacy of two types of sealant modalities over a 3-year period.
  
  
  METHODS
  Using a split-mouth randomised design, 1280 sealants were randomly applied on sound permanent second molars of 320 young patients aged between 12 and 16 years. Half of the teeth (n = 640) were sealed with a resin-modified glass ionomer cement (RMGIC) (Vitremer™, 3M ESPE) and the other half (n = 640) with a conventional light-cure, resin-based fissure sealant (LCRB) (Fluoroshield®, Dentsply Caulk). Teeth were evaluated at baseline, 6-, 12-, 18-, 24-, 30- and 36-month intervals with regard to retention and new caries development.
  
  
  RESULTS
  On the sealed occlusal surfaces after 3 years, 5.10% of RMGIC and 91.08% of LCRB sealants were totally intact and 6.37% of RMGIC and 7.65% of LCRB sealants were partially intact. New caries lesions were found in 20.06% of RMGIC sealed occlusal surfaces, compared to 8.91% for LCRB sealants.
  
  
  CONCLUSIONS
  The findings of the present clinical study suggest that RMGIC should be used only as a transitional sealant that can be applied to newly erupting teeth throughout the eruptive process, whereas LCRB sealants are used to successfully prevent occlusal caries lesions once an effective rubber dam can be achieved. It can be concluded that there are differences between the RMGIC and LCRB sealants over a 3-year period in terms of the retention rate and caries-preventive efficacy. RMGIC can serve as a simple and economic sealing solution, however provisional. Due to its poor retention rate, periodic recalls are necessary, even after 6 months, to eventually replace the lost sealant.
authors.affiliation: Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil. wagner_baseggio@yahoo.com.br
authors.forename: Wagner
authors.initials: W
authors.lastname: Baseggio
authors.forename: Fabiana Scarparo
authors.initials: FS
authors.lastname: Naufel
authors.forename: Denise César de Oliveira
authors.initials: DC
authors.lastname: Davidoff
authors.forename: Flávia Pardo Salata
authors.initials: FP
authors.lastname: Nahsan
authors.forename: Simon
authors.initials: S
authors.lastname: Flury
authors.forename: Jonas Almeida
authors.initials: JA
authors.lastname: Rodrigues
mesh_terms: D000293:Adolescent; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use*; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002648:Child; D003188:Composite Resins / Q000627:therapeutic use*; D003731:Dental Caries / Q000517:prevention & control*; D005899:Glass Ionomer Cements / Q000627:therapeutic use*; D006801:Humans; D055115:Light-Curing of Dental Adhesives; D010895:Pit and Fissure Sealants / Q000737:chemistry / Q000627:therapeutic use*; D011140:Polyurethanes / Q000627:therapeutic use*; D011446:Prospective Studies; D018709:Statistics, Nonparametric
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; D011140:Polyurethanes; C084550:Vitremer; C086661:Fluoroshield; D017438:Bisphenol A-Glycidyl Methacrylate