title: Old yeast can't handle the noise.
abstract: In this issue of Molecular Cell, Feser et al. (2010) show that aging yeast lose chromatin-associated histones and, furthermore, that correcting this deficiency robustly enhances replicative life span, indicating that loss of normal chromatin packing contributes to the aging process.
authors.affiliation: Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: McCormick
authors.forename: Brian K
authors.initials: BK
authors.lastname: Kennedy