title: Copper-catalyzed synthesis of α-amino imides from tertiary amines: Ugi-type three-component assemblies involving direct functionalization of sp3 C-Hs adjacent to nitrogen atoms.
abstract: α-Amino imides can be accessed straightforwardly from tertiary amines through copper-catalyzed three-component reactions involving the direct functionalization of sp(3) C-Hs adjacent to nitrogen atoms. This reaction has demonstrated a tolerance to a wide range of functionalizations and can be performed under very mild conditions. A plausible mechanism has been proposed in which an Ugi-type cascade assembly has been included.
authors.affiliation: Research Center of Biomedicine and Health, and College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310012, PR China.
authors.forename: Xin
authors.initials: X
authors.lastname: Ye
authors.forename: Chunsong
authors.initials: C
authors.lastname: Xie
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Pan
authors.forename: Laihong
authors.initials: L
authors.lastname: Han
authors.forename: Tian
authors.initials: T
authors.lastname: Xie
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007094:Imides / Q000138:chemical synthesis*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*
chemical_list: D000588:Amines; D007094:Imides; D003300:Copper; D009584:Nitrogen