Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS.
Sixty seven tropane alkaloids were identified in the organs of Datura stramonium L. by GC/MS. Nine new tropane alkaloids, 3,7-dihydroxy-6-propionyloxytropane, 6,7-dehydro-3-tigloyloxytropane, 3-tigloyloxy-6,7-epoxytropane, 3,7-dihydroxy-6-(2'-methylbutyryloxy)tropane, 6,7-dehydroapoatropine, 3-(3'-methoxytropoyloxy)tropane, 3-tigloyloxy-6-isobutyryloxy-7-hydroxytropane, 3-tropoyloxy-6-isobutyryloxytropane, 3β-tropoyloxy-6β-isovaleroyloxytropane were tentatively identified. The alkaloids cyclotropine, dihydroaposcopolamine, 6,7-dehydrohyoscyamine and 4'-hydroxylittorine are reported for the first time for the genus Datura and 6,7-dehydrotropine for the family Solanaceae. Hyoscyamine and scopolamine figure as the major tropane alkaloids in the plant organs.
El Bazaoui
Ahmed
A
Laboratoire de Recherches et d'Analyses Techniques et Scientifiques de la Gendarmerie Royale, Rabat, Maroc, BP, 6597 Rabat instituts Maroc, Morocco. gr.elbazaoui@yahoo.fr
Bellimam
My Ahmed
MA
Soulaymani
Abdelmajid
A
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D001285:Atropine / Q000032:analysis; D013286:Datura stramonium / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D012601:Scopolamine / Q000032:analysis; D014326:Tropanes / Q000737:chemistry / Q000302:isolation & purification*
D000470:Alkaloids; D010936:Plant Extracts; D014326:Tropanes; D001285:Atropine; D012601:Scopolamine