The threshold of insulin-induced hypophagia is lower in chicks selected for low rather than high juvenile body weight.
Chicks genetically selected for low juvenile body weight had a lower threshold of central insulin-induced decreased food and water intake and whole blood glucose concentration than those selected for juvenile high body weight. Plasma corticosterone concentration was increased but not differently between lines. Therefore, selection may have affected insulin sensitivity which may have then contributed to their hypo- and hyperphagia and differential body weights.
Smith
Marissa L
ML
Department of Biology, Radford University, East Main Street, Radford, VA 24142, USA.
Prall
Brian C
BC
Siegel
Paul B
PB
Cline
Mark A
MA
D000367:Age Factors; D000818:Animals; D001069:Appetite Regulation / Q000235:genetics / Q000502:physiology*; D001786:Blood Glucose / Q000502:physiology; D001835:Body Weight / Q000235:genetics* / Q000502:physiology; D002645:Chickens; D003345:Corticosterone / Q000097:blood; D004195:Disease Models, Animal; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D001068:Feeding and Eating Disorders / Q000139:chemically induced / Q000235:genetics* / Q000378:metabolism; D007328:Insulin / Q000494:pharmacology / Q000502:physiology*; D012641:Selection, Genetic
D001786:Blood Glucose; D007328:Insulin; D003345:Corticosterone