title: Comparison of different forms of dietary selenium supplementation on growth performance, meat quality, selenium deposition, and antioxidant property in broilers.
abstract: This study was conducted to investigate the effects of different sources of dietary selenium (Se) supplementation on growth performance, meat quality, Se deposition, and antioxidant property in broilers. A total of 600 one-day-old Ross 308 broilers with an average body weight (BW) of 44.30 ± 0.49 g were randomly allotted to three treatments, each of which included five replicates of 40 birds. These three groups received the same basal diet containing 0.04 mg Se/kg, supplemented with 0.15 mg Se/kg from sodium selenite (SS) or from L-selenomethionine (L-Se-methionine (Met)) or from D-selenomethionine (D-Se-Met). The experiment lasted 42 days. Both Se source and time significantly influenced (p < 0.01) drip loss of breast muscle. Supplementation with L-Se-Met and D-Se-Met were more effective (p < 0.05) in decreasing drip loss than SS. Besides, the pH value of breast muscle was also significantly influenced (p < 0.05) by time. The SS-supplemented diet increased more (p < 0.05) liver, kidney, and pancreas glutathione peroxidase (GSH-Px) activities than the D-Se-Met-supplemented diet. In addition, L-Se-Met increased more (p < 0.01) liver and pancreas GSH-Px activities than D-Se-Met. The antioxidant status was greatly improved in broilers of L-Se-Met-treated group in comparison with the SS-treated group and was illuminated by the increased glutathione (GSH) concentration in serum, liver, and breast muscle (p < 0.05); superoxide dismutase (SOD) activity in liver (p < 0.01); total antioxidant capability (T-AOC) in kidney, pancreas, and breast muscle (p < 0.05) and decreased malondialdehyde (MDA) concentration in kidney and breast muscle (p < 0.05) of broilers. Besides, supplementation with D-Se-Met was more effective (p < 0.01) in increasing serum GSH concentration and decreasing breast muscle MDA concentration than SS. L-Selenomethionine supplementation significantly increased GSH concentration in liver and breast muscle (p < 0.05); SOD activity in liver (p < 0.01); and T-AOC in liver, pancreas, and breast muscle (p < 0.05) of broilers, compared with broilers fed D-Se-Met diet. The addition of L-Se-Met and D-Se-Met increased (p < 0.01) Se concentration in serum and different organs studied of broilers in comparision with broilers fed SS diet. Therefore, dietary L-Se-Met and D-Se-Met supplementation could improve antioxidant capability and Se deposition in serum and tissues and reduce drip loss of breast muscle in broilers compared with SS. Besides, L-Se-Met is more effective than D-Se-Met in improving antioxidant status in broilers.
authors.affiliation: Feed Science Institute, College of Animal Science, Zhejiang University, No 164, Qiutao North Road, Hangzhou 310029, People's Republic of China.
authors.forename: Yongxia
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiuan
authors.initials: X
authors.lastname: Zhan
authors.forename: Xiwen
authors.initials: X
authors.lastname: Zhang
authors.forename: Rujuan
authors.initials: R
authors.lastname: Wu
authors.forename: Dong
authors.initials: D
authors.lastname: Yuan
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002645:Chickens; D019587:Dietary Supplements; D005978:Glutathione / Q000097:blood / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008315:Malondialdehyde / Q000097:blood; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism; D012643:Selenium / Q000008:administration & dosage / Q000494:pharmacology*; D012645:Selenomethionine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D008315:Malondialdehyde; D012645:Selenomethionine; D005979:Glutathione Peroxidase; D005978:Glutathione; D012643:Selenium