title: Surgically induced corneal necrotizing keratitis following LASIK in a patient with inflammatory bowel disease.
abstract: We describe a case of necrotizing keratitis that developed after laser in situ keratomileusis (LASIK) in a 50-year-old woman with inflammatory bowel disease. The patient had not disclosed her history of a total colectomy for recurrent ulcerative colitis and developed bilateral stromal inflammation and corneal melting along the flap edge with ulceration within 3 days of uneventful bilateral LASIK for myopia. She was aggressively managed with topical and systemic corticosteroid therapy. Flap infiltrates gradually resolved, with no relapse during the 12-month follow-up. This case highlights the importance of taking a detailed history, specifically addressing autoimmune diseases, before corneal refractive surgery.
authors.affiliation: London Vision Clinic, London, United Kingdom.
authors.forename: Glenn I
authors.initials: GI
authors.lastname: Carp
authors.forename: Thibault
authors.initials: T
authors.lastname: Verhamme
authors.forename: Marine
authors.initials: M
authors.lastname: Gobbe
authors.forename: William H
authors.initials: WH
authors.lastname: Ayliffe
authors.forename: Dan Z
authors.initials: DZ
authors.lastname: Reinstein
mesh_terms: D003082:Colectomy; D003093:Colitis, Ulcerative / Q000150:complications* / Q000601:surgery; D003315:Cornea / Q000473:pathology*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000209:etiology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D009336:Necrosis; D014792:Visual Acuity / Q000502:physiology