Comparison of BinaxNOW Influenza A&B assay and real-time reverse transcription polymerase chain reaction for diagnosis of influenza A pandemic (H1N1) 2009 virus infection in adult patients.
The BinaxNOW Influenza A&B assay was evaluated for the diagnosis of influenza A pandemic (H1N1) 2009 virus infection in 354 adult patients. The sensitivity, specificity, and positive and negative predictive values were 32%, 100%, 100%, and 67%, respectively. The analytic sensitivity of the assay was log₁₀5.0 tissue culture infective dose (TCID)₅₀/mL.
Gimeno
Concepción
C
Microbiology Service, Centro de Diagnóstico Biomédico, Consorcio Hospital General Universitario, Valencia 46014, Spain.
Bravo
Dayana
D
Ocete
Dolores
D
Tormo
Nuria
N
Navalpotro
David
D
Costa
Elisa
E
de Lomas
Juan García
JG
Navarro
David
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D017931:DNA Primers; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D009981:Influenza B virus / Q000276:immunology; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology; D008875:Middle Aged; D009305:Nasopharynx / Q000821:virology; D009960:Oropharynx / Q000821:virology; D058873:Pandemics; D011237:Predictive Value of Tests; D012367:RNA, Viral / Q000032:analysis* / Q000235:genetics / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D055815:Young Adult
D000914:Antibodies, Viral; D017931:DNA Primers; D012367:RNA, Viral