title: [Memory and intellectual disorders in patients with epilepsy: an analysis of the relationship between clinical characteristics and brain asymmetry].
abstract: Clinical characteristics and cognitive functions have been studied during the examination and treatment of 132 patients with epilepsy. It has been shown that both the epileptic process by itself and the antiepileptic therapy are predictors of the memory-intellectual impairment. The key risk factors of cognitive impairment are the younger age of patients at the onset of seizures, the higher frequency of seizures and the secondary generalization. We found the effect of left-sided motor asymmetry on the intellectual impairment that was more pronounced in men. The left-sided profile of brain asymmetry is an unfavorable prognostic factor of the disease development.
authors.forename: D M
authors.initials: DM
authors.lastname: Nazmetdinova
authors.forename: A V
authors.initials: AV
authors.lastname: Basamygin
authors.forename: V V
authors.initials: VV
authors.lastname: Kalinin
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology* / Q000503:physiopathology*; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology*; D008875:Middle Aged; D055815:Young Adult
chemical_list: D000927:Anticonvulsants