title: Use of a new absorbable sealing film for preventing postoperative cerebrospinal fluid leaks: remarks on a new approach.
abstract: Cerebrospinal fluid (CSF) leak is an adverse event that can affect the postoperative course of neurosurgical patients. Despite the large intra-operative use effective strategies as well as specific devices, CSF leak post-operative occurrence has been recently reported in up to 11% of cases. TissuePatchDural is a new sealant that is now available in neurosurgery in order to repair dural defects and, consequently, to prevent the postoperative formation of CSF fistulas. The device is a synthetic absorbable film that can actively create a firm temporary connection with the external dural surface and thus favour a satisfactory healing of the wound. The authors report a preliminary experience about the use of such device in 12 selected patients.
authors.affiliation: Department of Neurosurgery, Padua University Hospital, Padua, Italy. alessandro.dellapuppa@sanita.padova.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Della Puppa
authors.forename: Marta
authors.initials: M
authors.lastname: Rossetto
authors.forename: Renato
authors.initials: R
authors.lastname: Scienza
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D065634:Cerebrospinal Fluid Leak; D002559:Cerebrospinal Fluid Rhinorrhea / Q000517:prevention & control; D005260:Female; D006016:Glycolates / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D006016:Glycolates; D014014:Tissue Adhesives; C031149:glycolic acid