title: Prostate brachytherapy seed reconstruction using C-arm rotation measurement and motion compensation.
abstract: During prostate brachytherapy, C-arm flouroscopy images are used for a qualitative assessment of the procedure. Three dimensional reconstruction of the implanted seeds can be used for intraoperative dosimetry and quantitative assessment. Accurate C-arm pose estimation is necessary for 3D localization of the seeds. We propose to measure the C-arm rotation angles and computationally compensate the inevitable C-arm translational motion to estimate the pose. We compensate the oscillation, sagging and wheel motion of the C-arm using a three-level optimization algorithm, without which the reconstruction can fail. We validated our approach on simulated and 10 data sets from 5 patients and gained on average 99.1% success rate, 0.33 mm projection error and computation time of less than one minute per patient, which are clinically excellent results.
authors.affiliation: Queen's University, Canada.
authors.forename: Ehsan
authors.initials: E
authors.lastname: Dehghan
authors.forename: Junghoon
authors.initials: J
authors.lastname: Lee
authors.forename: Mehdi
authors.initials: M
authors.lastname: Moradi
authors.forename: Xu
authors.initials: X
authors.lastname: Wen
authors.forename: Gabor
authors.initials: G
authors.lastname: Fichtinger
authors.forename: Septimiu E
authors.initials: SE
authors.lastname: Salcudean
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D009038:Motion; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D011881:Radiotherapy, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*