title: Nonhealing wound due to Rhodococcus equi in an apparently immunocompetent patient, revealing CD8+ T-lymphocyte deficiency.
abstract: We describe a case of a nonhealing wound due to Rhodococcus equi. Failure of the wound to heal led to immunological investigations and the discovery of a previously unknown CD8+ T-lymphocyte deficit responsible for the chronic infection. The infection was cured after a 3-month course of a combination of antibiotics.
authors.affiliation: Department of Infectious Diseases, Service de Maladies Infectieuses, CHU Dupuytren, 2 Ave. Martin Luther King, 87000 Limoges, France. e.denes@free.fr
authors.forename: Eric
authors.initials: E
authors.lastname: Denes
authors.forename: Dominique
authors.initials: D
authors.lastname: Peignon-Orsoni
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Terrade
mesh_terms: D000193:Actinomycetales Infections / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D004359:Drug Therapy, Combination / Q000379:methods; D005260:Female; D006801:Humans; D008231:Lymphopenia / Q000150:complications*; D008875:Middle Aged; D016929:Rhodococcus equi / Q000276:immunology* / Q000302:isolation & purification*; D016896:Treatment Outcome; D014946:Wound Infection / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents