title: Hospital-acquired acute kidney injury.
abstract: Acute kidney injury (AKI) is a common clinical syndrome in hospitalized patients associated with high morbidity and mortality rates. Despite several years of improvement in the medical care of the severely ill, there has been little improvement in outcome. Furthermore, effective means of preventing and treating AKI have remained elusive. Although dialysis has been the mainstay of treating AKI for > 40 years, several questions regarding its application remain unsettled, including method (continuous vs intermittent), timing, and dose. The purpose of this review is to summarize recent advances in the epidemiology and treatment of AKI in hospitalized patients.
authors.affiliation: Division of Renal Diseases and Hypertension, Section of Critical Care Nephrology, University of Texas Medical School at Houston, Houston, TX 77030, USA. kevin.w.finkel@uth.tmc.edu
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Finkel
authors.forename: Amber S
authors.initials: AS
authors.lastname: Podoll
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy*; D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D016638:Critical Illness / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D003404:Creatinine