Resolution and absolute configuration assignment of a chiral hemicryptophane molecular cage.
The racemic hemicryptophane molecular cage 2 was resolved by semipreparative HPLC on Whelk-O1 column. The absolute configuration of each isolated enantiomer was established from the analysis of their circular dichroism spectra and assigned as P-(+)-2 and M-(-)-2.
Perraud
Olivier
O
Laboratoire de Chimie, Ecole Normale Supérieure de Lyon, F-69364 Lyon, France.
Raytchev
Pascal Dimitrov
PD
Martinez
Alexandre
A
Dutasta
Jean-Pierre
JP