title: Joseph Lister's surgical revolution.
abstract: Joseph Lister (1827-1912), renowned British surgeon-scientist, introduced to the world the use and appreciation of the antiseptic method for the prevention of wound sepsis. Armed with the ideas of Louis Pasteur (1822-1895) regarding the role of microorganisms in infections or the so-called germ theory of disease, he advanced the surgical field by using antiseptics, such as carbolic acid, in the treatment of contaminated wounds. These developments constituted a real surgical revolution. No breakthrough before Lister's, except perhaps the discovery of anesthesia, had contributed to such an incredible advancement in relationship to the surgical arena. After 1867, the year in which Lister published his remarkable paper in Lancet, it was possible to appropriately treat or prevent wound infections with the use of antiseptics at the site of the operated wound. Lister's method was complicated but produced its desired effect--to diminish wound morbidity and patient mortality. His contribution was secured for future generations and a surgical revolution had begun!
authors.forename: Luis H
authors.initials: LH
authors.lastname: Toledo-Pereyra
mesh_terms: D000891:Anti-Infective Agents, Local; D004739:England; D013502:General Surgery; D049672:History, 19th Century; D049673:History, 20th Century
chemical_list: D000891:Anti-Infective Agents, Local