[Comprehensive examination of the female urogenital tract infection by polymerase chain reaction using multiplex test systems].
The results of the polymerase chain reaction studies performed in 2006-2008 were used to make a retrospective analysis of the detection of urogenital herpesvirus infections in reproductive-aged women constituting the urban population of the central region of Russia. The study used both monotarget and mutiplex test systems to detect herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human herpesvirus types 6 and 7. A total of about 7.500 referrals; the detection rate for HSV was about 1%; that for CMV was from 0.3 in 2006 to 1% in 2008; that for EBV was from 0.1% in 2006 to 0.3% in 2008. More than a half of HSV-, CMV-, or EBY-positive samples also contained DNA of other causative agents and some samples did two pathogens or more. Multiplex test systems for herpesviruses considerably enhance the efficiency of diagnostic studies and reduce the material and time costs of diagnosis.
Demkin
V V
VV
Kurinov
A M
AM
Kuz'micheva
R A
RA
Karlina
V P
VP
Korneva
I N
IN
Suchkov
S V
SV
D000328:Adult; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D052776:Female Urogenital Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology*; D006558:Herpes Genitalis / Q000453:epidemiology / Q000382:microbiology / Q000821:virology; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods*; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D014626:Vaginal Smears; D055815:Young Adult
D004279:DNA, Viral