Obstruction of the tricuspid valve orifice by a huge right atrial myxoma associated with the Carney complex: a case report.
Carney complex (CNC) is an inherited autosomal dominant disorder associated with multiple neoplasms. Myxomas associated with CNC differ from their sporadic forms because the former usually develop at a younger age and they may be multicentric and have a tendency to recur. Furthermore, their localization may be atypical. We report the case of a 57-year-old man, with a huge right atrial myxoma obstructing the tricuspid valve orifice. A diagnosis of CNC was established by genetic analysis. The importance of early diagnosis and an adequate follow-up is emphasized.
Affronti
Alessandro
A
Cardiac Surgery Unit, Ospedale Santa Maria della Misericordia, Perugia, Italy. aaffronti@hotmail.com
Di Bella
Isidoro
I
Prontera
Paolo
P
Da Col
Uberto
U
Ramoni
Enrico
E
Donti
Emilio
E
Paris
Marco
M
Ragni
Temistocle
T
D006348:Cardiac Surgical Procedures; D056733:Carney Complex / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit / Q000235:genetics; D005500:Follow-Up Studies; D006325:Heart Atria; D006338:Heart Neoplasms / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D009232:Myxoma / Q000150:complications* / Q000175:diagnosis; D057089:Pathology, Molecular; D014264:Tricuspid Valve Stenosis / Q000175:diagnosis / Q000209:etiology*
D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; C517834:PRKAR1A protein, human