ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism.
The ESR1 promoter microsatellite (TA)n was reported as a potential functional polymorphism. In a case-control study, we were unable to demonstrate any association between (TA)n and nonsyndromic cryptorchidism in Italian and Spanish study populations.
Lo Giacco
Deborah
D
Andrology Service, Molecular Biology Laboratory, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain.
Ars
Elisabet
E
Bassas
Lluis
L
Galan
José Jorge
JJ
Rajmil
Osvaldo
O
Ruíz
Patricia
P
Caffaratti
Jorge
J
Guarducci
Elena
E
Ruiz-Castané
Eduard
E
Krausz
Csilla
C
D000328:Adult; D002648:Child; D003456:Cryptorchidism / Q000235:genetics*; D047628:Estrogen Receptor alpha / Q000235:genetics*; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D007558:Italy; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*; D013030:Spain
C506487:ESR1 protein, human; D047628:Estrogen Receptor alpha