Facile fabrication of networked patterns and their superior application to realize the virus immobilized networked pattern circuit.
A facile route to fabricate a protein-immobilized network pattern circuit for rapid and highly sensitive diagnosis was developed via the evaporation directed impromptu patterning method and selective avian influenza virus (AIV) immobilization. The response to the 10 fg mL(-1) anti-AI antibody demonstrates that this easy and simple circuit has about 1000 times higher sensitivity compared to those of conventional approaches.
Choi
Kyung Min
KM
NanoCentury KAIST Institute, Graduate School of EEWS (WCU), Department of Materials Science & Engineering, KAIST, Daejeon 305-701, Korea.
Lee
Seok Jae
SJ
Choi
Jung Hoon
JH
Park
Tae Jung
TJ
Park
Jong Wan
JW
Shin
Weon Ho
WH
Kang
Jeung Ku
JK
D000595:Amino Acid Sequence; D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D001717:Birds / Q000821:virology; D004560:Electricity; D006046:Gold / Q000737:chemistry; D055767:Immobilized Proteins / Q000737:chemistry*; D053124:Influenza A Virus, H5N1 Subtype / Q000302:isolation & purification; D053127:Influenza A Virus, H9N2 Subtype / Q000302:isolation & purification; D009980:Influenza A virus / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000175:diagnosis; D037742:Nanotubes, Carbon / Q000737:chemistry; D010446:Peptide Fragments / Q000737:chemistry; D014764:Viral Proteins / Q000737:chemistry*; D014835:Volatilization
D055767:Immobilized Proteins; D037742:Nanotubes, Carbon; D010446:Peptide Fragments; D014764:Viral Proteins; D006046:Gold