DNA strand exchange catalyzed by molecular crowding in PEG solutions.
DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology.
Feng
Bobo
B
Department of Chemical and Biological Engineering, Chalmers University of Technology, S-41296, Gothenburg, Sweden.
Frykholm
Karolin
K
Nordén
Bengt
B
Westerlund
Fredrik
F
D002384:Catalysis; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D009690:Nucleic Acid Conformation; D044367:Phase Transition; D011092:Polyethylene Glycols / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D044366:Transition Temperature
D012996:Solutions; D011092:Polyethylene Glycols; D004247:DNA