title: Gut microbiota and related diseases: clinical features.
abstract: Intestinal microbiota is essential for gut homeostasis. Specifically, the microorganisms inhabiting the gut lumen interact with the intestinal immune system, supply key nutrients for the major components of the gut wall, and modulate energy metabolism. Host-microbiome interactions can be either beneficial or deleterious, driving gastrointestinal lymphoid tissue activities and shaping gut wall structures. This overview briefly focuses on the potential role played by abnormalities in gut microbiota and relative responses of the gastrointestinal tract in the determination of important pathological conditions such as the irritable bowel syndrome, inflammatory bowel diseases and colorectal cancer.
authors.affiliation: Department of Clinical Medicine, St. Orsola-Malpighi Hospital, University of Bologna, Building No. 5, Via Massarenti, 9, 40138, Bologna, Italy. v.stanghellini@unibo.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Stanghellini
authors.forename: Giovanni
authors.initials: G
authors.lastname: Barbara
authors.forename: Cesare
authors.initials: C
authors.lastname: Cremon
authors.forename: Rosanna
authors.initials: R
authors.lastname: Cogliandro
authors.forename: Alexandra
authors.initials: A
authors.lastname: Antonucci
authors.forename: Veronica
authors.initials: V
authors.lastname: Gabusi
authors.forename: Chiara
authors.initials: C
authors.lastname: Frisoni
authors.forename: Roberto
authors.initials: R
authors.lastname: De Giorgio
authors.forename: Valentina
authors.initials: V
authors.lastname: Grasso
authors.forename: Mauro
authors.initials: M
authors.lastname: Serra
authors.forename: Roberto
authors.initials: R
authors.lastname: Corinaldesi
mesh_terms: D003106:Colon / Q000187:drug effects / Q000382:microbiology*; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000382:microbiology; D003469:Culture; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000382:microbiology*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000382:microbiology; D043183:Irritable Bowel Syndrome / Q000382:microbiology* / Q000473:pathology; D007558:Italy / Q000453:epidemiology; D054892:Metagenome; D019936:Probiotics; D012007:Rectum / Q000187:drug effects / Q000382:microbiology*; D012307:Risk Factors