title: Quality of life of children with sleep-disordered breathing treated with adenotonsillectomy.
abstract: OBJECTIVE
  To assess the quality of life of UK children with sleep-disordered breathing undergoing adenotonsillectomy, by using the Obstructive Sleep Apnoea 18 questionnaire and determining score changes and effect sizes.
  
  
  METHODS
  Prospective, longitudinal study.
  
  
  METHODS
  The otolaryngology department of a university teaching hospital in Northern England.
  
  
  METHODS
  Twenty-eight children for whom adenotonsillectomy was planned as treatment for sleep-disordered breathing, and who had either a clinical history consistent with obstructive sleep apnoea or a polysomnographic diagnosis.
  
  
  METHODS
  The Obstructive Sleep Apnoea 18 questionnaire, a previously validated, disease-specific quality of life assessment tool; changes in questionnaire scores and effect sizes were assessed.
  
  
  METHODS
  The Obstructive Sleep Apnoea 18 questionnaire was administered to each child's parent pre-operatively, then again at the follow-up appointment. Questionnaire scores ranged from 1 to 7. Score changes were analysed using the paired t-test; effect sizes were calculated using 95 per cent confidence intervals.
  
  
  RESULTS
  Complete data were obtained for 22 children (mean age, 61 months). Ten had undergone pre-operative polysomnography. Twenty-one children underwent adenotonsillectomy (one underwent tonsillectomy). Median follow up was eight weeks (interquartile range, six to 11 weeks). Following surgery, the overall mean score improvement was 2.6 (p < 0.0001) and the mean effect size 2.4 (95 per cent confidence interval 1.9 to 2.8). There were significant improvements in each of the individual questionnaire domains, i.e. sleep disturbance (mean score change 3.9, p < 0.0001), physical suffering (2.2, p < 0.0001), emotional distress (2.0, p = 0.0001), daytime problems (1.8, p = 0.0001) and caregiver concerns (2.6, p < 0.0001).
  
  
  CONCLUSIONS
  In these children with sleep-disordered breathing treated by adenotonsillectomy, Obstructive Sleep Apnoea 18 questionnaire results indicated significantly improved mean score changes and effect sizes across all questionnaire domains, comparing pre- and post-operative data.
authors.affiliation: Department of Otolaryngology, James Cook University Hospital, Middlesbrough, UK. steven_m_powell@hotmail.com
authors.forename: S M
authors.initials: SM
authors.lastname: Powell
authors.forename: M
authors.initials: M
authors.lastname: Tremlett
authors.forename: D A
authors.initials: DA
authors.lastname: Bosman
mesh_terms: D000233:Adenoidectomy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D017286:Polysomnography; D011788:Quality of Life; D012891:Sleep Apnea Syndromes / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D011795:Surveys and Questionnaires / Q000592:standards*; D014068:Tonsillectomy; D016896:Treatment Outcome; D006113:United Kingdom