title: Effectiveness of sealing active proximal caries lesions with an adhesive system: 1-year clinical evaluation.
abstract: The objective of this study was to evaluate the effectiveness of a therapeutic sealant to arrest non-cavitated proximal carious lesion progression. The study population comprised 44 adolescents who had bitewing radiographs taken for caries diagnosis. Non-cavitated lesions extending up to half of dentin thickness were included in the sample. In the experimental group (n = 33), the proximal caries-lesion surfaces were sealed with an adhesive (OptiBond Solo, Kerr) after tooth separation. The control group (n = 11) received no treatment, except for oral hygiene instructions including use of dental floss. Follow-up radiographs were taken after one year and were analyzed in comparison with baseline radiographs. In a blind study setting, visual readings were performed by two examiners, blinded to whether the examined radiograph was baseline or follow-up, and whether it concerned a test or control lesion. The efficacy of sealing treatment was evaluated by the McNemar test (0.05). About 22% of the sealed lesions showed reduction, 61% showed no change and 16% showed progression. For the control lesions, the corresponding values were 27%, 36% and 36% respectively. The number of lesions that showed reduction and no changes were merged and therefore 83.3% of the sealed lesions and 63.6% of the control lesions were considered clinically successful. No statistical significance was detected (p > 0.05). In the course of 1 year, sealing proximal caries lesions was not shown to be superior to lesion monitoring.
authors.affiliation: Pediatric Dentistry Department, School of Dentistry, University of Oeste de Santa Catarina, Joaçaba, SC, Brazil.
authors.forename: Clarisse
authors.initials: C
authors.lastname: Abuchaim
authors.forename: Marina
authors.initials: M
authors.lastname: Rotta
authors.forename: Rosa Helena Miranda
authors.initials: RH
authors.lastname: Grande
authors.forename: Alessandro Dourado
authors.initials: AD
authors.lastname: Loguercio
authors.forename: Alessandra
authors.initials: A
authors.lastname: Reis
mesh_terms: D000293:Adolescent; D000328:Adult; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use*; D003731:Dental Caries / Q000000981:diagnostic imaging / Q000628:therapy*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D010895:Pit and Fissure Sealants / Q000627:therapeutic use*; D011859:Radiography; D015203:Reproducibility of Results; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D017220:Dentin-Bonding Agents; D010895:Pit and Fissure Sealants; D017438:Bisphenol A-Glycidyl Methacrylate