title: [The congenital afibrinogenemia: case report].
abstract: The deficiency in factor I or fibrinogen is a largely unknown genetic disease. It is a rare condition inherited as an autosomal recessive, whose clinical events are variable, ranging from moderate to minimal bleeding or cataclysmic hemorrhage. We report a case of congenital afibrinogenemia in a 17 years-old patient hospitalized in surgical ICU for hemoperitoneum medium abundance discovered by abdominal ultrasound performed before a picture of abdominopelvic pain lasting for 24 hours. Exploration led to the diagnosis of congenital afibrinogenemia with favorable evolution with a contribution of factor deficient. Through this case we raise the problem of congenital afibrinogenemia in diagnosis and the peculiarities of its management.
authors.affiliation: Département de biochimie, Faculté de médecine, Sousse, Tunisia. imenebraham@yahoo.fr
authors.forename: Imen
authors.initials: I
authors.lastname: Brahem
authors.forename: Bassem
authors.initials: B
authors.lastname: Charfeddine
authors.forename: Haythem
authors.initials: H
authors.lastname: Chraiti
authors.forename: Jihene
authors.initials: J
authors.lastname: Ben Abdallah
authors.forename: Leila
authors.initials: L
authors.lastname: Ben Othmen
authors.forename: Souhir
authors.initials: S
authors.lastname: Neffati
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ali Smach
authors.forename: Affef
authors.initials: A
authors.lastname: Ltaief
authors.forename: Monia
authors.initials: M
authors.lastname: Ksourri
authors.forename: Hedi
authors.initials: H
authors.lastname: Dridi
authors.forename: Khalifa
authors.initials: K
authors.lastname: Limem
mesh_terms: D000293:Adolescent; D000347:Afibrinogenemia / Q000151:congenital* / Q000235:genetics / Q000628:therapy; D001803:Blood Transfusion; D005260:Female; D006465:Hemoperitoneum / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D006801:Humans