title: Tight glycemic control: what do we really know, and what should we expect?
abstract: Tight glycemic control has engendered large numbers of investigations, with conflicting results. The world has largely embraced intensive insulin as a practice, but applies this therapy with great variability in the manner of glucose control and measurement. The present commentary reviews what we actually know with certainty from this vast sea of literature, and what we can expect looking forward.
authors.affiliation: Department of Surgery, Tufts Medical Center, 750 Washington Street, Box 4630, Boston, MA 02111, USA. snasraway@tuftsmedicalcenter.org
authors.forename: Stanley A
authors.initials: SA
authors.lastname: Nasraway
authors.forename: Rishi
authors.initials: R
authors.lastname: Rattan
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism*; D038321:Glycemic Index / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000188:drug therapy; D007003:Hypoglycemia / Q000097:blood / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D007328:Insulin / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin