title: [The clinical and functional status of the stomach and small intestine in patients with chronic inflammatory bowel diseases concurrent with chronic opisthorchiasis].
abstract: To study the impact of Opisthorchis infestation on the upper digestive tract and small bowel in chronic inflammatory bowel diseases, the authors examined 164 patients with inflammatory bowel diseases, including 71 patients with ulcerative colitis and 45 with Crohn's disease without parasitosis and 48 with chronic opisthorchiasis (31 with ulcerative colitis and 17 with Crohn's disease). A control group consisted of 20 healthy individuals and 20 patients with chronic opisthorchiasis. A diagnosis was established by colonofibroscopy and a morphological study of colonic biopsy specimens. Gastric mucosal atrophic changes and motor evacuatory disorders as duodenogastric reflux were significantly more frequently encountered in inflammatory bowel diseases concurrent with chronic opisthorchiasis. The presence of Opisthorchis infestation significantly worsened fat and carbohydrate malabsorption in the small bowel in inflammatory bowel diseases.
authors.forename: V A
authors.initials: VA
authors.lastname: Burkovskaia
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
authors.forename: O N
authors.initials: ON
authors.lastname: Glinskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Markidonova
authors.forename: E L
authors.initials: EL
authors.lastname: Naumova
authors.forename: I O
authors.initials: IO
authors.lastname: Gibadulina
authors.forename: E A
authors.initials: EA
authors.lastname: Kvach
authors.forename: L A
authors.initials: LA
authors.lastname: Akimova
authors.forename: A V
authors.initials: AV
authors.lastname: Baksht
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001284:Atrophy / Q000473:pathology; D050260:Carbohydrate Metabolism; D002908:Chronic Disease; D004383:Duodenogastric Reflux / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D007413:Intestinal Mucosa / Q000473:pathology / Q000503:physiopathology; D007421:Intestine, Small / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D013270:Stomach / Q000503:physiopathology*; D013552:Swine