title: Memory of chirality in cascade rearrangements of enediynes.
abstract: The cascade rearrangement of chiral enediynes 1c-e, involving successively 1,3-proton shift, Saito-Myers cyclization, 1,5-hydrogen atom transfer, and intramolecular coupling of the resulting biradical, proceeded at 80 °C to form tri- and tetracyclic heterocycles possessing a quaternary stereogenic center with a very high level of memory of chirality.
authors.affiliation: Laboratoire Chimie Provence, LCP UMR 6264, Aix-Marseille Université, Faculté des Sciences St Jérôme, Avenue Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France. malek.nechab@univ-provence.fr
authors.forename: Malek
authors.initials: M
authors.lastname: Nechab
authors.forename: Damien
authors.initials: D
authors.lastname: Campolo
authors.forename: Julien
authors.initials: J
authors.lastname: Maury
authors.forename: Patricia
authors.initials: P
authors.lastname: Perfetti
authors.forename: Nicolas
authors.initials: N
authors.lastname: Vanthuyne
authors.forename: Didier
authors.initials: D
authors.lastname: Siri
authors.forename: Michèle P
authors.initials: MP
authors.lastname: Bertrand
mesh_terms: D003500:Cyclization; D053281:Enediynes / Q000737:chemistry*; D008958:Models, Molecular; D013237:Stereoisomerism
chemical_list: D053281:Enediynes