title: [A clinicopathological study on bronchoplasty in the treatment of lung cancer.].
abstract: BACKGROUND
  To investigate the characteristics of proximal bronchial invasion of lung cancer , and to provide some insights into the treatment of lung cancer by bronchoplasty.
  
  
  METHODS
  Proximal bronchi of 58 operatively resected specimens of lung cancer by bronchoplasty were selected for different cross-sectional pathological study.
  
  
  RESULTS
  The ratio of cancer remnant of incision margin in the patients of bronchial wedge resection was significantly higher than that of sleeve resection ( P < 0. 01) . Of the cancerous invasion at the proximal bronchial wall , 96. 1 % was observed to be less than 1. 5cm apart from the margin of the cancer. The direct invasion of tumour cells through the mucous layer , submucosal layer and multiple layers was 3. 9 % , 23. 5 % and 72. 5 % respectively. The extension of cancer infiltration was closely correlated with the histopathologic type of cancer , mode of invasion and TNM staging. The indirect invasion of metastatic lymph nodes in adenocarcinoma was more likely at the adventitial layer of proximal bronchial wall.
  
  
  CONCLUSIONS
  For radical operation , it is imperative to keep a distance of 1. 5cm or more between the incision margin of the bronchus and the tumor margin , to take sleeve lobectomy or pneumonectomy and to completely clear the hilar and mediastinal lymph nodes.
authors.affiliation: Department of Thoracic Surgery , Henan Cancer Hospital , Zhengzhou , Henan 450003 , P. R. China.
authors.forename: J
authors.initials: J
authors.lastname: Xu
authors.forename: Q
authors.initials: Q
authors.lastname: Yu
authors.forename: H
authors.initials: H
authors.lastname: Jiang
authors.forename: Z
authors.initials: Z
authors.lastname: Gao
authors.forename: Z
authors.initials: Z
authors.lastname: Long
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Qiao