Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites.
Streptomyces clavuligerus is an important industrial strain that produces a number of antibiotics, including clavulanic acid and cephamycin C. A high-quality draft genome sequence of the S. clavuligerus NRRL 3585 strain was produced by employing a hybrid approach that involved Sanger sequencing, Roche/454 pyrosequencing, optical mapping, and partial finishing. Its genome, comprising four linear replicons, one chromosome, and four plasmids, carries numerous sets of genes involved in the biosynthesis of secondary metabolites, including a variety of antibiotics.
Song
Ju Yeon
JY
Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Jeong
Haeyoung
H
Yu
Dong Su
DS
Fischbach
Michael A
MA
Park
Hong-Seog
HS
Kim
Jae Jong
JJ
Seo
Jeong-Sun
JS
Jensen
Susan E
SE
Oh
Tae Kwang
TK
Lee
Kye Joon
KJ
Kim
Jihyun F
JF
D053898:Biosynthetic Pathways / Q000235:genetics; D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D010957:Plasmids; D017422:Sequence Analysis, DNA / Q000379:methods; D013302:Streptomyces / Q000235:genetics*
D004269:DNA, Bacterial