title: Design and testing of an advanced implantable neuroprosthesis with myoelectric control.
abstract: An implantable stimulator-telemeter (IST-12) was developed for applications in neuroprosthetic restoration of limb function in paralyzed individuals. The IST-12 provides 12 stimulation channels and two myoelectric signal (MES) channels. The MES circuitry includes a two-channel multiplexer, preamplifier, variable gain amplifier/bandpass filter, full-wave rectifier, and bin integrator. Power and control signals are transmitted from an external control unit to the IST-12 through an inductive link. Recorded MES signals are telemetered back to the external control unit through the same inductive link. Following bench testing, one device was implanted chronically in a dog for 15 months and evaluated. Conditions were identified in which MES could be recorded with minimal stimulus artifact. The ability to record MES in the presence of stimulation was verified, confirming the potential of the IST-12 to be used as a myoelectric controlled neuroprosthesis.
authors.affiliation: Louis Stokes Veterans Affairs Medical Center, Cleveland, OH 44109, USA. rhart@fescenter.org
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Hart
authors.forename: Niloy
authors.initials: N
authors.lastname: Bhadra
authors.forename: Fred W
authors.initials: FW
authors.lastname: Montague
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Kilgore
authors.forename: P Hunter
authors.initials: PH
authors.lastname: Peckham
mesh_terms: D000818:Animals; D001676:Biofeedback, Psychology / Q000295:instrumentation*; D004285:Dogs; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004576:Electromyography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D009069:Movement Disorders / Q000534:rehabilitation*; D019736:Prostheses and Implants; D013686:Telemetry / Q000295:instrumentation*; D013813:Therapy, Computer-Assisted / Q000295:instrumentation*