title: Multiple band frequency analysis in a child of medial temporal lobe ganglioglioma.
abstract: We report a 1-year 6-month-old girl with ganglioglioma in the right medial temporal lobe who showed epileptic spasms in clusters. Spasms occasionally followed a dazed and fearful gaze. Interictal electroencephalography (EEG) showed diffuse bursts of slightly irregular high-voltage spikes and slow waves without hypsarrhythmia. The findings on ictal EEG, single-photon emission computed tomography, and F-18 fluorodeoxyglucose positron emission tomography indicated focus on the right medial temporal lobe. Ictal fast rhythmic activity analysis of scalp EEG by multiple band frequency analysis showed gamma rhythms at 65-80 Hz with a high spectral power around the tumor area. Epileptic spasms completely disappeared after tumor resection. These findings suggest that the cerebral cortex may be a source of epileptic spasms and indicate the possibility of usefulness of fast activity analysis in this condition.
authors.affiliation: Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry (NCNP), 4-1-1, Kodaira, Tokyo 187 8551, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Mizuno
authors.forename: Eiji
authors.initials: E
authors.lastname: Nakagawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakuma
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Saito
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Komaki
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugai
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sasaki
authors.forename: Akio
authors.initials: A
authors.lastname: Takahashi
authors.forename: Taisuke
authors.initials: T
authors.lastname: Otsuki
authors.forename: Kotoe
authors.initials: K
authors.lastname: Sakihara
authors.forename: Masumi
authors.initials: M
authors.lastname: Inagaki
mesh_terms: D001932:Brain Neoplasms / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D018303:Ganglioglioma / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D013702:Temporal Lobe / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome