Simple organofluorine compounds giving field-dependent 13C and 19F NMR spectra with complex patterns: higher order effects and cross-correlated relaxation.
The CF(3) signals in the (13)C{(1)H} spectrum of 1,1,1,3,3,3-hexafluoroisopropyl alcohol and the (CF(3))(2) CH signals in the corresponding triflate exhibit much greater complexity than might first be expected. The same holds for the (13)C satellites in the (19)F spectra. Complex patterns appear because of higher order effects resulting from the combination of a relatively large four-bond (19)F-(19)F J coupling in the ((13)CF(3))(12)CH((12)CF(3))-containing isotopomer and a typical large one-bond (13)C/(12)C isotope effect on the (19)F chemical shift. This complexity cannot be eliminated at very high magnetic field strengths. The triflate (CF(3))(2)CH-O-SO(2)CF(3) presents still additional complexity because of the presence of two different types of CF(3) groups exhibiting (6)J(FF) in any of the isotopomers and the chemical shift differences in hertz between the various (19)F signals in the two different (13)CF(3)-containing isotopomers. In addition, the presence of a small (5)J(CF) in the ((13)CF(3))((12)CF(3))(12)CH-O-SO(2) (12)CF(3) isotopomer is revealed only through simulations. The hexafluoroisopropyl CF(3) groups in the alcohol and triflate and the SO(2)CF(3) group in the triflate apparently provide the first examples of cross-correlated relaxation in (13)CF(3) groups. An analysis of the spectra in the context of previously reported work highlights the novel aspects of our findings. In particular, for each part of the complex hexafluoroisopropyl CF(3) quartet, peak height and linewidth variations resulting from cross-correlated relaxation are observed. These variations within a group of (13)C signals reflect different spin-lattice and spin-spin relaxation rates for the transitions within that group arising from higher order coupling effects.
Alemany
Lawrence B
LB
Rice University, Department of Chemistry, MS-60 and Shared Equipment Authority, MS-100, Houston, TX 77251-1892, USA. lalemany@rice.edu
Malloy
Thomas B
TB
Nunes
Megan M
MM
D002247:Carbon Isotopes; D005461:Fluorine / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D020005:Propanols / Q000737:chemistry*; D011522:Protons; D012015:Reference Standards; D006845:Hydrocarbons, Fluorinated
D002247:Carbon Isotopes; D005461:Fluorine; D020005:Propanols; D011522:Protons; C001337:hexafluoroisopropanol; D006845:Hydrocarbons, Fluorinated