Phosphoramidate prodrugs deliver with potency against hepatitis C virus.
Mehellou
Youcef
Y
Medical Research Council, Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. y.mehellou@dundee.ac.uk
D000577:Amides / Q000737:chemistry / Q000494:pharmacology*; D019380:Anti-HIV Agents / Q000737:chemistry / Q000494:pharmacology*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D006151:Guanosine / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D016174:Hepacivirus / Q000187:drug effects*; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D010756:Phosphoric Acids / Q000737:chemistry / Q000494:pharmacology*; D011355:Prodrugs / Q000737:chemistry / Q000494:pharmacology*; D011741:Pyrimidine Nucleosides / Q000737:chemistry / Q000494:pharmacology*
D000577:Amides; D019380:Anti-HIV Agents; D010756:Phosphoric Acids; D011355:Prodrugs; D011741:Pyrimidine Nucleosides; D006151:Guanosine; C011067:phosphoramidic acid; D012321:DNA-Directed RNA Polymerases