title: Thyroglobulin gene is associated with premature ovarian failure.
abstract: Variants of the thyroglobulin gene were significantly associated with premature ovarian failure in a Korean population. Three single nucleotide polymorphisms and one haplotype were found to be associated with a significant increase in the risk for premature ovarian failure.
authors.affiliation: Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Republic of Korea.
authors.forename: Jung-A
authors.initials: JA
authors.lastname: Pyun
authors.forename: HyunJun
authors.initials: H
authors.lastname: Kang
authors.forename: JiHye
authors.initials: J
authors.lastname: Kim
authors.forename: Dong Hyun
authors.initials: DH
authors.lastname: Cha
authors.forename: KyuBum
authors.initials: K
authors.lastname: Kwack
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D007037:Hypothyroidism / Q000453:epidemiology* / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D016649:Primary Ovarian Insufficiency / Q000453:epidemiology* / Q000235:genetics*; D012307:Risk Factors; D013954:Thyroglobulin / Q000235:genetics*
chemical_list: D013954:Thyroglobulin