title: [Effects of acupuncture-drug compound anesthesia on perioperative inflammatory factors in patients undergoing cardiac surgery].
abstract: OBJECTIVE
  To explore the effect of acupuncture-drug compound anesthesia on immune function in patients with extracorporeal circulation undergoing cardiac surgery.
  
  
  METHODS
  Thirty cases undergoing cardiac surgery which included atrial septal defect neoplasty, ventricular septal defect neoplasty, mitral valve replacement and pulmonary valve coarctotomy were randomly divided into group A and group B, 15 cases in each group. Group A was given general anesthesia plus acupuncture at Neiguan (PC 6), Lieque (LU 7) and Yunmen (LU 2), and group B was given simple general anesthesia. Tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2) and interleukin-10 (IL-10) levels before and after surgery were compared.
  
  
  RESULTS
  The level of TNF-alpha was increased and the levels of IL-2 and IL-10 in the serum were decreased in both groups after extracorporeal circulation for 2 h and 24 h, and the ranges of all changes were more less in group A (all P < 0.05).
  
  
  CONCLUSIONS
  Compared with simple general anesthesia, acupuncture-drug compound anesthesia can improve immune suppression partially in the perioperative periods under the same conditions of controlling anesthesia degree.
authors.affiliation: Department of Cardiothoracic Surgery, Renji Hospital, Medical College of Shanghai Jiaotong University, Shanghai 200127, China.
authors.forename: Jiang-Gui
authors.initials: JG
authors.lastname: Shan
authors.forename: Song
authors.initials: S
authors.lastname: Xue
authors.forename: Gen-Xing
authors.initials: GX
authors.lastname: Xu
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Wang
authors.forename: Feng
authors.initials: F
authors.lastname: Lian
authors.forename: Sha
authors.initials: S
authors.lastname: Liu
authors.forename: Zhen-Lei
authors.initials: ZL
authors.lastname: Hu
authors.forename: Ri-Tai
authors.initials: RT
authors.lastname: Huang
mesh_terms: D015667:Acupuncture Analgesia; D000328:Adult; D000768:Anesthesia, General; D006348:Cardiac Surgical Procedures; D005260:Female; D006331:Heart Diseases / Q000097:blood / Q000276:immunology* / Q000601:surgery*; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D016753:Interleukin-10 / Q000097:blood; D007376:Interleukin-2 / Q000097:blood; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D055815:Young Adult
chemical_list: D018836:Inflammation Mediators; D007376:Interleukin-2; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10