title: In vitro activity of conventional antifungal agents against Scedosporium apiospermum isolates recovered from clinical and environmental samples in Nigeria.
abstract: In vitro susceptibilities of Scedosporium apiospermum isolates recovered from clinical and environmental samples in Nigeria were tested against ten conventional antifungal agents, namely: amphotericin B, nystatin, flucytosine, itraconazole, posaconazole, fluconazole, voriconazole, micafungin, ketoconazole, and terbinafine using the CLSI M38-A broth dilution reference method. The isolates showed varied response/sensitivities to the antifungal agents tested. This is probably the first documented testing of Scedosporium apiospermum isolates from Africa in general and Nigeria in particular against a broad range of conventional antifungal agents.
authors.affiliation: University of Nigeria, Department of Microbiology, Nsukka, Nigeria. nwezemeka@yahoo.com
authors.forename: E I
authors.initials: EI
authors.lastname: Nweze
authors.forename: J I
authors.initials: JI
authors.lastname: Okafor
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008271:Mycetoma / Q000382:microbiology*; D009549:Nigeria; D021681:Scedosporium / Q000187:drug effects* / Q000302:isolation & purification; D012988:Soil Microbiology
chemical_list: D000935:Antifungal Agents