Hodgkin lymphoma and nephrotic syndrome in childhood.
An association between nephrotic syndrome and extrarenal neoplasia was described for the first time in 1922. Since then a large number of cases have been published, few of them describing the link between Hodgkin disease (HD) and nephrotic syndrome (NS). It shows that the incidence of nephrotic syndrome in Hodgkin lymphoma is less than 1%. Till date, to the best of author's knowledge, there are about 50 pediatric cases published, no one among Italian children. In the present paper, the authors report 2 cases observed in their department in the 7 yrs period.
Farruggia
Piero
P
Unit of Paediatric Haematology and Oncology, G. Di Cristina Children Hospital, A.R.N.A.S, Via Benedettini 1, 90134, Palermo, Italy. farruggia.oep@ospedalecivicopa.org
Trizzino
Antonino
A
Maringhini
Silvio
S
Grigoli
Antonella
A
Sapia
Chiara
C
D'Alessandro
Mariella
M
Tropia
Serena
S
D'Angelo
Paolo
P
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D015897:Comorbidity; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D009404:Nephrotic Syndrome / Q000453:epidemiology*; D010257:Paraneoplastic Syndromes / Q000453:epidemiology*; D011241:Prednisone / Q000627:therapeutic use; D011344:Procarbazine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D011344:Procarbazine; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone