title: Synthesis and antioxidant activity of some new coumarinyl-1,3-thiazolidine-4-ones.
abstract: A series of Schiff's bases (E)-N-2-aryliden-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetohydrazides 2a-l and N-(2-(substituted phenyl)-4-oxo-thiazolidin-3-yl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetamides 3a-l were synthesized and evaluated for their antioxidant activity by the phosphomolybdenum method. Most of the Schiff's bases and thiazolidine-4-ones bearing two hydroxyl groups on the phenyl ring showed excellent antioxidant activity in comparison with ascorbic acid. Preliminary investigation on cytotoxic and antifungal activity was done on some representative samples.
authors.affiliation: Department of Applied Chemistry and Ecology, Faculty of Food Technology, J. J. Strossmayer University, Franje Kuhaca 20, 31 000 Osijek, Croatia. mcacic@ptfos.hr
authors.forename: Milan
authors.initials: M
authors.lastname: Cacić
authors.forename: Maja
authors.initials: M
authors.lastname: Molnar
authors.forename: Bojan
authors.initials: B
authors.lastname: Sarkanj
authors.forename: Elizabeta
authors.initials: E
authors.lastname: Has-Schön
authors.forename: Valentina
authors.initials: V
authors.lastname: Rajković
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry; D001205:Ascorbic Acid / Q000737:chemistry; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry; D010084:Oxidation-Reduction; D053778:Thiazolidines / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000447:Aldehydes; D000890:Anti-Infective Agents; D000975:Antioxidants; D053778:Thiazolidines; D008982:Molybdenum; D001205:Ascorbic Acid