title: Invited commentary.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N Wolfe St, Tower 711, Baltimore, MD 21287, USA. chogue2@jhmi.edu
authors.forename: Charles W
authors.initials: CW
authors.lastname: Hogue
mesh_terms: D000367:Age Factors; D000368:Aged; D001024:Aortic Valve Stenosis / Q000453:epidemiology* / Q000601:surgery; D002545:Brain Ischemia / Q000175:diagnosis* / Q000453:epidemiology; D003072:Cognition Disorders / Q000209:etiology*; D015897:Comorbidity; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors