Drug-induced permeabilization of S. cerevisiae.
Budding yeast are not permeable to many drugs. This unit provides a protocol in which polygodial is used to permeabilize the cell membrane, thereby allowing budding yeast cells to be treated with drugs that otherwise would be ineffective.
Mayan
Maria D
MD
MRC Clinical Sciences Centre, Imperial College, London, United Kingdom.
D000935:Antifungal Agents / Q000378:metabolism*; D002462:Cell Membrane / Q000187:drug effects* / Q000502:physiology*; D002463:Cell Membrane Permeability / Q000187:drug effects*; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000502:physiology*; D012717:Sesquiterpenes / Q000378:metabolism*
D000935:Antifungal Agents; D012717:Sesquiterpenes; C034380:polygodial