title: Binge eating disorder and menstrual cycle in unmedicated women with bipolar disorder.
abstract: OBJECTIVE
  Weight increase is a problem in women with bipolar disorder (BD). Furthermore, there is evidence that both binge eating disorder (BED) and menstrual cycle abnormalities occur more frequently in women with affective disorders than in the general population. We investigated whether there is a clinical link between the two disorders and menstrual cycle.
  
  
  METHODS
  Epidemiological and clinical variables associated with both BD and BED were assessed as well as menstrual cycle influence.
  
  
  RESULTS
  The prevalence of BED in the sample was 28.8%. Menstrual cycle significantly influenced BED in all participants in that BED became worse prior to menses. 80% of the participants noticed regular weight gain prior to menses.
  
  
  CONCLUSIONS
  BED is a common comorbidity in unmedicated subjects with BD, as is overweight. In women with BD menstrual cycle should be taken into consideration, as it can worsen the BD itself and associated comorbidities such as BED and overweight. Alteration in menstrual cycle-associated eating behavior should be routinely assessed in women with BD.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Charité Campus Mitte, University Medicine Berlin, Germany.
authors.forename: Nikola
authors.initials: N
authors.lastname: Schoofs
authors.forename: Frank
authors.initials: F
authors.lastname: Chen
authors.forename: Peter
authors.initials: P
authors.lastname: Bräunig
authors.forename: Thomas
authors.initials: T
authors.lastname: Stamm
authors.forename: Stephanie
authors.initials: S
authors.lastname: Krüger
mesh_terms: D000328:Adult; D056912:Binge-Eating Disorder / Q000453:epidemiology / Q000503:physiopathology* / Q000523:psychology; D001714:Bipolar Disorder / Q000453:epidemiology / Q000503:physiopathology* / Q000523:psychology; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D018709:Statistics, Nonparametric; D055815:Young Adult