title: Expected changes in clinical measures of adiposity during puberty.
abstract: BACKGROUND
  Clinicians use several measures to estimate adiposity. Body mass index (BMI), although not a measure of adiposity, is commonly used to define weight status. Percent body fat (%BF) measures total body fatness, which is composed of central and peripheral fat, estimated by waist circumference (WC) and skinfold thickness, respectively. Abnormal increases in fat during puberty may reflect an increased risk of developing cardiovascular disease. Therefore, it is important to establish the normal patterns of change in clinically relevant measures of adiposity.
  
  
  OBJECTIVE
  To describe the normal patterns of change in clinical measures of adiposity during puberty.
  
  
  METHODS
  Multilevel modeling and linear regression analyses of 642 children in Project HeartBeat!, aged 8-18 years (non-black and black), who had assessments of BMI, %BF, WC, sums of 2- and 6-skinfolds, and pubertal stage (PS) triennially between 1991 and 1995.
  
  
  RESULTS
  In males, the normal pattern from PS1 to PS5 is for %BF to decrease, skinfold thickness to remain stable, and WC to increase. However, after adjusting for height, WC does not change. In females, %BF remains stable from PS1 to PS5, whereas skinfold thickness increases. As in males waist-height ratio does not change, indicating that central adiposity does not normally increase during puberty. Although BMI increases in both genders and races from PS1 to PS5, mean values at PS5 were well below 25 kg/m(2).
  
  
  CONCLUSIONS
  During puberty, increase in %BF is abnormal in females and even more so in males. Likewise, increase in waist-height ratio is also abnormal and may suggest an increased risk for adiposity-associated morbidity.
authors.affiliation: Department of Pediatrics, University of Utah, Salt Lake City, Utah 84158, USA. nicole.mihalopoulos@hsc.utah.edu
authors.forename: Nicole L
authors.initials: NL
authors.lastname: Mihalopoulos
authors.forename: Richard
authors.initials: R
authors.lastname: Holubkov
authors.forename: Paul
authors.initials: P
authors.lastname: Young
authors.forename: Shifan
authors.initials: S
authors.lastname: Dai
authors.forename: Darwin R
authors.initials: DR
authors.lastname: Labarthe
mesh_terms: D050154:Adiposity / Q000502:physiology*; D000293:Adolescent; D001741:Black or African American / Q000706:statistics & numerical data; D015992:Body Mass Index; D002648:Child; D005260:Female; D006801:Humans; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D011627:Puberty / Q000502:physiology*; D012737:Sex Factors; D012885:Skinfold Thickness; D055105:Waist Circumference; D044465:White People / Q000706:statistics & numerical data