title: Identifying respiratory viruses in nasal mucus from children.
abstract: Large amounts of respiratory viruses are shed in nasal secretions by children. Nasal mucus was compared with nasopharyngeal swabs as a source for respiratory virus testing. Multiplex reverse transcription-polymerase chain reaction detected virus in nasal mucus specimens in 73% (11/15) of positive cases, demonstrating the potential utility of less invasive specimens when a highly sensitive method is used for respiratory virus detection.
authors.affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA. rosemary.she-bender@hsc.utah.edu
authors.forename: Rosemary C
authors.initials: RC
authors.lastname: She
authors.forename: Edward W
authors.initials: EW
authors.lastname: Taggart
authors.forename: Roland
authors.initials: R
authors.lastname: Ruegner
authors.forename: Weston C
authors.initials: WC
authors.lastname: Hymas
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Bender
authors.forename: Peter
authors.initials: P
authors.lastname: Weir
authors.forename: Cathy A
authors.initials: CA
authors.lastname: Petti
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009093:Mucus / Q000821:virology*; D009297:Nasal Mucosa / Q000821:virology*; D009305:Nasopharynx / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*; D017201:Virus Shedding; D014780:Viruses / Q000145:classification* / Q000302:isolation & purification*