title: Cross-modality assessment and planning for pulmonary trunk treatment using CT and MRI imaging.
abstract: Congenital heart defect is the primary cause of death in newborns, due to typically complex malformation of the cardiac system. The pulmonary valve and trunk are often affected and require complex clinical management and in most cases surgical or interventional treatment. While minimal invasive methods are emerging, non-invasive imaging-based assessment tools become crucial components in the clinical setting. For advanced evaluation and therapy planning purposes, cardiac Computed Tomography (CT) and cardiac Magnetic Resonance Imaging (cMRI) are important non-invasive investigation techniques with complementary properties. Although, characterized by high temporal resolution, cMRI does not cover the full motion of the pulmonary trunk. The sparse cMRI data acquired in this context include only one 3D scan of the heart in the end-diastolic phase and two 2D planes (long and short axes) over the whole cardiac cycle. In this paper we present a cross-modality framework for the evaluation of the pulmonary trunk, which combines the advantages of both, cardiac CT and cMRI. A patient-specific model is estimated from both modalities using hierarchical learning-based techniques. The pulmonary trunk model is exploited within a novel dynamic regression-based reconstruction to infer the incomplete cMRI temporal information. Extensive experiments performed on 72 cardiac CT and 74 cMRI sequences demonstrated the average speed of 110 seconds and accuracy of 1.4mm for the proposed approach. To the best of our knowledge this is the first dynamic model of the pulmonary trunk and right ventricle outflow track estimated from sparse 4D cMRI data.
authors.affiliation: Integrated Data Systems, Siemens Corporate Research, Princeton, USA.
authors.forename: Dime
authors.initials: D
authors.lastname: Vitanovski
authors.forename: Alexey
authors.initials: A
authors.lastname: Tsymbal
authors.forename: Razvan Ioan
authors.initials: RI
authors.lastname: Ionasec
authors.forename: Bogdan
authors.initials: B
authors.lastname: Georgescu
authors.forename: Martin
authors.initials: M
authors.lastname: Hubert
authors.forename: Andrew
authors.initials: A
authors.lastname: Taylor
authors.forename: Silvia
authors.initials: S
authors.lastname: Schievano
authors.forename: Shaohua Kevin
authors.initials: SK
authors.lastname: Zhou
authors.forename: Joachim
authors.initials: J
authors.lastname: Hornegger
authors.forename: Dorin
authors.initials: D
authors.lastname: Comaniciu
mesh_terms: D000465:Algorithms; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*