title: [Microbiological diagnosis of gas gangrene caused by Clostridium septicum (a clinical case)].
abstract: Microscopy of gram-stained impression smears is used for the rapid diagnosis of microorganisms in the wound. The shin tissues of patient P. with suspected gas gangrene of lower extremity soft tissues were microscopically found to have gram-positive spore-forming bacteria that were morphologically similar to C. bifermentans that were identified as C. septicum on cultural diagnosis. The pathogenic C. septicum strain spores were likely to be formed in the macroorganism upon exposure of the pathogen to a patient's defense factors and to a package of therapeutic measures. Microbiological data should be used only in combination with clinical and instrumental findings and the results of other laboratory studies when the optimal technology is chosen to treat gas infection. By keeping in mind that there may be clostridial gangrene in the patients and the experience of clinicians and bacteriologists may be insufficient in diagnosing this pathology, it is necessary to strengthen the training of physicians in the diagnosis of this pathology.
authors.forename: E D
authors.initials: ED
authors.lastname: Men'shikova
authors.forename: G P
authors.initials: GP
authors.lastname: Titova
authors.forename: V I
authors.initials: VI
authors.lastname: Kartavenko
authors.forename: V A
authors.initials: VA
authors.lastname: Sokolov
authors.forename: A K
authors.initials: AK
authors.lastname: Shabanov
authors.forename: D D
authors.initials: DD
authors.lastname: Men'shikov
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D052557:Clostridium septicum / Q000302:isolation & purification*; D017809:Fatal Outcome; D005738:Gas Gangrene / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008297:Male; D009104:Multiple Trauma / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents