A model of host response to a multi-stage pathogen.
We model the immune surveillance of a pathogen which passes through n immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be subject to immune regulation. This corresponds to the system's unique asymptotically stable fixed point.
Delgado-Eckert
Edgar
E
Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland.
Shapiro
Michael
M
D000818:Animals; D020031:Epstein-Barr Virus Infections / Q000276:immunology / Q000821:virology; D004854:Herpesvirus 4, Human / Q000276:immunology; D054884:Host-Pathogen Interactions / Q000276:immunology*; D018448:Models, Immunological