Evaluation of alveolar socket response to Angelus MTA and experimental light-cure MTA.
OBJECTIVE
The aim of this study was to evaluate the rat alveolar socket response to implanted polyethylene tubes filled with a light-cured MTA or Angelus MTA.


METHODS
Fifty-seven Wistar rats received an implant filled with one of the materials in the dental socket of the right central incisor. After 30, 60, and 90 days, animals were killed, and the right hemimaxillas were removed and processed to be analyzed on light microscopy. After embedding in paraffin, 6-μm-thick sections were obtained and stained with hematoxylin and eosin. Qualitative and quantitative analyses of the reaction were performed.


RESULTS
It was observed that the light-cured MTA presented a similar response compared with Angelus MTA, characterized by the reduction of the chronic inflammatory response and organization of the alveolar bone close to the materials, especially at the 90th day of observation.


CONCLUSIONS
It was concluded that both materials were well accepted by the alveolar tissue of rats, with the formation of mineralized tissue close to the materials.
Gomes-Filho
João Eduardo
JE
Department of Endodontics, Araçatuba School of Dentistry, Universidade Estadual Paulista, Araçatuba, Brazil. joao@foa.unesp.br
de Moraes Costa
Mariana Teixeira
MT
Cintra
Luciano Tavares Ângelo
LT
Lodi
Carolina Simonetti
CS
Duarte
Paulo Carvalo Tobias
PC
Okamoto
Roberta
R
Bernabé
Pedro Felício Estrada
PF
Nery
Mauro Juvenal
MJ
Cannon
Mark
M
D017607:Aluminum Compounds / Q000494:pharmacology*; D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology; D002113:Calcification, Physiologic / Q000187:drug effects / Q000502:physiology; D017610:Calcium Compounds / Q000494:pharmacology*; D004338:Drug Combinations; D005347:Fibroblasts / Q000473:pathology; D005355:Fibrosis; D015726:Giant Cells / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008264:Macrophages / Q000473:pathology; D008297:Male; D008437:Maxilla / Q000187:drug effects / Q000473:pathology; D009336:Necrosis; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology; D010087:Oxides / Q000494:pharmacology*; D020959:Polyethylene / Q000494:pharmacology; D019736:Prostheses and Implants; D051381:Rats; D017208:Rats, Wistar; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D017640:Silicates / Q000494:pharmacology*; D013997:Time Factors; D020390:Tooth Socket / Q000187:drug effects* / Q000473:pathology
D017607:Aluminum Compounds; D001672:Biocompatible Materials; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D020959:Polyethylene