title: Organochlorine pesticide levels in umbilical cord blood of newborn in Veracruz, Mexico.
abstract: Organochlorine pesticides accumulate in lipid rich compartments of organisms. During pregnancy, the compounds pass through the placental barrier appear in cord blood. The aim of this study was to monitor the levels of organochlorine pesticides in 70 umbilical cord blood samples taken during deliveries in Veracruz in 2009. For organochlorine pesticides, only the presence β-HCH (4%, 3.9 μg/L median concentration on wet weight), pp'DDE (100%, 0.7 μg/L) and pp'DDT (4%, 1.4 μg/L) were detected. The total pool of samples divided according to sex of new born babies, showed no statistical differences among median concentrations. The number of deliveries considered as a determinant contamination factor affirmed there were no statistical differences among median concentrations; however pp'DDE levels increased from the one to two childbirth groups. Age of pregnant women as a discriminate factor manifests in a significant increase in contamination levels among first, second and third tertile. In general, umbilical cord blood samples in Veracruz contained organochlorine pesticides, especially pp'DDE, confirming the presence of these compounds in the environment and their transfer from the mother to the developing fetus.
authors.affiliation: University of Veracruz, Xalapa, Mexico.
authors.forename: Margarita
authors.initials: M
authors.lastname: Herrero-Mercado
authors.forename: S M
authors.initials: SM
authors.lastname: Waliszewski
authors.forename: M
authors.initials: M
authors.lastname: Caba
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Valenzuela
authors.forename: F
authors.initials: F
authors.lastname: Hernández-Chalate
mesh_terms: D000328:Adult; D003634:DDT / Q000097:blood; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006581:Hexachlorobenzene / Q000097:blood; D001556:Hexachlorocyclohexane / Q000097:blood; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood*; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D010575:Pesticides / Q000097:blood*
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D003633:Dichlorodiphenyl Dichloroethylene; D006581:Hexachlorobenzene; D001556:Hexachlorocyclohexane; D003634:DDT