Drug-eluting stent for unprotected left main coronary artery disease: early and mid-term outcomes.
BACKGROUND
PCI is increasingly performed in patients with ULMCA disease. The efficacy and safety of drug-eluting stents in ULMCA disease have been reported.


OBJECTIVE
To evaluate the early and mid-term clinical outcome of the Percutaneous Coronary Intervention (PCI) with Drug-Eluting stent (DES) in unprotected left main coronary artery (ULMCA) disease patients.


METHODS
PCI with DES was performed with 90 consecutive patients having ULMCA disease between January 2006 and June 2009.


RESULTS
At a median follow-up of 22.8 +/- 12.2 months, major adverse cardiac or cerebrovascular events (MACCE) occurred in 11 (12.2%) patients. There were seven (7.8%) deaths including two (2.2%) cardiac deaths and five (5.6%) non-cardiac deaths. There was one MI (1.1%), and four (4.4%) target vessel revascularization. Restenosis in the left main occurred only in two patients (2.2%) and definite stent thrombosis occurred in two patients (2.2%).


CONCLUSIONS
The present study demonstrates that PCI with Drug-Eluting stent implantation in unprotected left main coronary artery disease is a safe form of treatment and has favorable outcomes.
Tassanawiwat
Worawut
W
Sappasitthiprasong Hospital, Ubonratchathani, Thailand. worawutwalla@yahoo.com
Mahavanakul
Weera
W
Thanakitcharu
Praprut
P
Komolsart
Piyarat
P
Chansod
Sopida
S
Sookananchai
Bancha
B
Wongvipaporn
Chaiyasith
C
Kiatchoosakun
Songsak
S
Cheiniwat
Sakda
S
Tresukosol
Damras
D
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D023903:Coronary Restenosis / Q000175:diagnosis / Q000453:epidemiology; D023921:Coronary Stenosis / Q000175:diagnosis / Q000453:epidemiology; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013785:Thailand / Q000453:epidemiology; D013997:Time Factors; D016896:Treatment Outcome