title: Evaluation of evidence for the psychotic subtyping of post-traumatic stress disorder.
abstract: Psychotic symptoms may occur in 15-64% of individuals with post-traumatic stress disorder, suggesting that the syndrome could be subtyped in a similar fashion to mood disorders. In our study of 1800 psychiatric out-patients who completed comprehensive diagnostic interviews, the lifetime prevalence of psychotic symptoms in people with PTSD was 17% (odds ratio (OR) = 3.48, 95% CI 2.32-5.21). However, after excluding people with comorbid conditions also known to be associated with psychotic symptoms this dropped to only 2.5% (OR) = 0.60, 95% CI 0.08-4.52). In contrast, rates of psychotic major depression did not change after excluding these same comorbidities. Our results do not support the official psychotic subtyping of PTSD.
authors.affiliation: Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, and Psychosocial Research Program, Butler Hospital, Providence 02906, USA. Brandon_Gaudiano@brown.edu
authors.forename: Brandon A
authors.initials: BA
authors.lastname: Gaudiano
authors.forename: Mark
authors.initials: M
authors.lastname: Zimmerman
mesh_terms: D000328:Adult; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000175:diagnosis / Q000453:epidemiology*; D015203:Reproducibility of Results; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*