[Verotoxin as a major laboratory criterion for Escherichia coli O157-induced enteric infection complicated by hemolytic uremic syndrome in infants in the Omsk region].
The paper presents the results of etiological interpretation of the outbreak of Escherichia coli O157-induced enteric infection complicated by hemolytic uremic syndrome in Omsk in spring 2009. Seventeen infants aged 5 months to 2.5 years were examined; of them 9 patients were on hemodialysis. The diagnosis was verified in 7 children, by isolating verotoxin after fecal enrichment on the concentrating nutrient RIDA Enrichment Bouillon medium containing bile salts and mitomycin C, E. coli O157:H7 cultures on the sorbitol medium and/or by identifying E. coli O157 DNA. Six (4 having verotoxin) infants were found to have rotavirus and noro-virus antigens or DNA/RNA, which may make a contribution into the development of mixed infection and increase the risk of complications.
Dolgikh
T I
TI
Kaftyreva
L A
LA
Voĭtovich
M A
MA
Podkolzin
A T
AT
Galileĭskaia
S B
SB
Lazareva
L I
LI
D002675:Child, Preschool; D002947:Cities; D004403:Dysentery / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D004927:Escherichia coli Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000302:isolation & purification*; D005243:Feces / Q000737:chemistry; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D007223:Infant; D006435:Renal Dialysis; D022603:Shiga Toxins / Q000032:analysis*; D012800:Siberia / Q000453:epidemiology
D022603:Shiga Toxins