Novel mechanisms of endothelial dysfunction in diabetes.
Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This condition increases the risk of developing coronary, cerebrovascular, and peripheral arterial disease fourfold. Endothelial dysfunction is a major contributor to the pathogenesis of vascular disease in diabetes mellitus patients and has recently received increased attention. In this review article, some recent developments that could improve the knowledge of diabetes-induced endothelial dysfunction are discussed.
Yang
Guang
G
Department of Vascular Biology Center, Medical College of Georgia, Augusta, GA, USA.
Lucas
Rudolf
R
Caldwell
Ruth
R
Yao
Lin
L
Romero
Maritza J
MJ
Caldwell
Robert W
RW