title: Disseminated intravascular coagulation with intracranial haematoma in neonatal congenital syphilis.
abstract: Disseminated intravascular coagulation (DIC) although a well known complication in neonatal sepsis is extremely rare in congenital syphilis and there are scanty reports of this entity in the literature. Intracranial bleeding following DIC in neonatal congenital syphilis is even rarer, and has been reported only once earlier. We are reporting the second case of neonatal DIC with intracranial haematoma due to congenital syphilis in a newborn. Our patient also had clinical and biochemical evidence of hepatitis which predisposes to DIC. Extensive investigations and emergent use of imaging modalities including ultrasound and CT scan led to early diagnosis and treatment in our patient, who could therefore be salvaged from an otherwise life threatening disease.
authors.affiliation: Department of Radiodiagnosis and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India. shabnamgrover@yahoo.com
authors.forename: Shabnam Bhandari
authors.initials: SB
authors.lastname: Grover
authors.forename: Simendra
authors.initials: S
authors.lastname: Mahato
authors.forename: Harish
authors.initials: H
authors.lastname: Chellani
authors.forename: Sumita
authors.initials: S
authors.lastname: Saluja
authors.forename: G Preethi
authors.initials: GP
authors.lastname: Rajalakshmi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D042241:Early Diagnosis; D006408:Hematoma, Subdural / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006505:Hepatitis / Q000150:complications / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D010949:Plasma; D017713:Platelet Transfusion; D012307:Risk Factors; D013590:Syphilis, Congenital / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents