title: Aptamer-induced self-assembly of a NIR-emissive platinum(II) terpyridyl complex for label- and immobilization-free detection of lysozyme and thrombin.
abstract: With the aptamer-induced self-assembly feature of NIR-emissive platinum(ii) terpyridyl complex, a "proof-of-principle" concept in label- and immobilization-free probing strategies of lysozyme and thrombin has been demonstrated with good selectivity and specificity.
authors.affiliation: Institute of Molecular Functional Materials (Areas of Excellence Scheme, University Grants Committee, Hong Kong) and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
authors.forename: Margaret Ching-Lam
authors.initials: MC
authors.lastname: Yeung
authors.forename: Keith Man-Chung
authors.initials: KM
authors.lastname: Wong
authors.forename: Yuk Kai Tiu
authors.initials: YK
authors.lastname: Tsang
authors.forename: Vivian Wing-Wah
authors.initials: VW
authors.lastname: Yam
mesh_terms: D052157:Aptamers, Nucleotide / Q000378:metabolism*; D015374:Biosensing Techniques / Q000379:methods*; D004800:Enzymes, Immobilized / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D009113:Muramidase / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D009944:Organoplatinum Compounds / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013379:Substrate Specificity; D013917:Thrombin / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D004800:Enzymes, Immobilized; D009944:Organoplatinum Compounds; D009113:Muramidase; D013917:Thrombin