title: The effect of ibuprofen on postoperative hemorrhage following tonsillectomy in children.
abstract: The objective of the study was to evaluate the effect of ibuprofen on hemorrhage after tonsillectomy in children. All charts of children, who underwent tonsillectomy with or without adenoidectomy, were reviewed. The age at the time of surgery ranged between 3 and 16 years (mean age = 7.55 ± 3.01 years). Children were divided into two groups based on the drugs used for postoperative pain relief. Group I received paracetamol after surgery. Group II received ibuprofen after surgery. A total of 62 patients received ibuprofen and 109 patients were given paracetamol. Post-tonsillectomy hemorrhage occurred in seven (4.1%) children, primary hemorrhage was noted in five patients and secondary hemorrhage occurred in two patients. While 3 of 62 children (4.8%) who were given ibuprofen had postoperative hemorrhage, 4 of 109 patients (3.7%) who were given paracetamol had hemorrhage There was no significant difference in hemorrhage rates between these two groups (p > 0.05). Hemorrhage following tonsillectomy is rare and frequently occurs in the early postoperative period. There is no significant increased risk of hemorrhage after ibuprofen administration and it can be used safely for post-tonsillectomy pain relief.
authors.affiliation: Department of Otorhinolaryngology, Duzce Medical Faculty, Duzce University, Duzce, Turkey. hyaman1975@yahoo.com
authors.forename: Huseyin
authors.initials: H
authors.lastname: Yaman
authors.forename: Abdullah
authors.initials: A
authors.lastname: Belada
authors.forename: Suleyman
authors.initials: S
authors.lastname: Yilmaz
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects / Q000627:therapeutic use*; D015994:Incidence; D008297:Male; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D019106:Postoperative Hemorrhage / Q000139:chemically induced / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D014068:Tonsillectomy / Q000009:adverse effects*; D014421:Turkey / Q000453:epidemiology
chemical_list: D018712:Analgesics, Non-Narcotic; D007052:Ibuprofen