[Carcinogenic activity of the pesticide propoxur].
Wistar rats were fed propoxur in their diet at 0, 500, 3000, and 8000 ppm during throughout their life. The number of tumors was equal in the control and experimental groups. These were hemoblastoses and breast and uterine tumors. All tumors occurred spontaneously in the rats. A few experimental animals were found to have bladder epithelial hyperplasia that might be pretumorous; however, no bladder tumors were detected. It is concluded that the investigations revealed no carcinogenic activity of propoxur.
Pylev
L N
LN
Vasil'eva
L A
LA
Smirnova
O V
OV
Khrustalev
S A
SA
Trukhina
G M
GM
D000818:Animals; D015197:Carcinogenicity Tests; D002273:Carcinogens / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D009369:Neoplasms / Q000139:chemically induced; D001074:Propoxur / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D002273:Carcinogens; D007306:Insecticides; D001074:Propoxur