title: [Expression and significance of Fas/APO-1 and Bcl-2 protein in human lung cancer.].
abstract: BACKGROUND
  To investigate the role of Fas/APO-1 and Bcl-2 in oncogenesis and progression of lung cancer.
  
  
  METHODS
  The expression of Fas/APO-1 and Bcl-2 protein were detected in 65 lung cancer tissues and 46 normal lung tissues by immunohistochemistry.
  
  
  RESULTS
  The positive rate of Fas/APO-1 protein expression in lung cancer tissues was 56. 92 % , which was significantly lower than that in normal lung tissues (82. 61 %) ( P < 0. 01) . The positive rate of Bcl-2 protein expression was 46. 15 %. It was significantly higher than that in normal lung tissues (6. 52 %) ( P < 0. 01) .
  
  
  CONCLUSIONS
  Both Fas/APO-1 and Bcl-2 may play an role in the oncogenesis and progression of lung cancer.
authors.affiliation: Department of Thoracocardiac Surgery , 175th Hospital of People's Liberation Army , Zhangzhou , Fujian 363000 , P. R. China.
authors.forename: Y
authors.initials: Y
authors.lastname: Yi
authors.forename: X
authors.initials: X
authors.lastname: Gan
authors.forename: C
authors.initials: C
authors.lastname: Lin
authors.forename: X
authors.initials: X
authors.lastname: Hu