Theoretical description of a DNA-linked nanoparticle self-assembly.
Nanoparticles tethered with DNA strands are promising building blocks for bottom-up nanotechnology, and a theoretical understanding is important for future development. Here we build on approaches developed in polymer physics to provide theoretical descriptions for the equilibrium clustering and dynamics, as well as the self-assembly kinetics of DNA-linked nanoparticles. Striking agreement is observed between the theory and molecular modeling of DNA-tethered nanoparticles.
Hsu
Chia Wei
CW
Department of Physics, Wesleyan University, Middletown, Connecticut 06459, USA.
Sciortino
Francesco
F
Starr
Francis W
FW
D004247:DNA / Q000737:chemistry*; D004058:Diffusion; D007700:Kinetics; D008956:Models, Chemical; D056004:Molecular Dynamics Simulation; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D013696:Temperature
D004247:DNA