title: Field trial of praziquantel for control of fishborne zoonotic trematodes in reservoir hosts in Vietnam.
abstract: This field trial was conducted to determine whether 40 or 75 mg/kg of praziquantel is suitable for treatment of fishborne zoonotic trematodes (FZT) in naturally infected dogs (n=10) and cats (n=11). Three days after treatment all animals at either dose were negative for small trematode eggs. In two cats and one dog treated with 75 mg/kg, however, a few damaged eggs were found 3 days post-treatment; no small trematode eggs were seen in these animals at day 14 post-treatment. In addition, at the 75 mg dose, two cats and two dogs experienced vomiting or diminished appetite. Therefore a praziquantel dose of 40 mg/kg is suggested for treatment of FZT in dogs and cats.
authors.affiliation: National Institute of Veterinary Research, 86 Truong Chinh, Hanoi, Viet Nam. linhlananh2001@yahoo.com
authors.forename: Nguyen Thi Lan
authors.initials: NT
authors.lastname: Anh
authors.forename: Henry
authors.initials: H
authors.lastname: Madsen
authors.forename: Dao Thi Ha
authors.initials: DT
authors.lastname: Thanh
authors.forename: Anders
authors.initials: A
authors.lastname: Dalsgaard
authors.forename: K Darwin
authors.initials: KD
authors.lastname: Murrell
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy* / Q000469:parasitology; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000469:parasitology; D005393:Fish Diseases / Q000469:parasitology* / Q000635:transmission; D005399:Fishes; D006801:Humans; D010270:Parasite Egg Count; D011223:Praziquantel / Q000627:therapeutic use*; D014200:Trematoda; D014201:Trematode Infections / Q000188:drug therapy / Q000662:veterinary*; D014744:Vietnam / Q000453:epidemiology; D015047:Zoonoses
chemical_list: D011223:Praziquantel