title: Myelodysplastic syndromes in older adults.
abstract: Myelodsyplastic syndromes are a collection of disorders that affect the hematopoietic development of myeloid cells in the bone marrow. Although this disorder is curable by way of allogeneic stem cell transplantation, advanced age, limited donor availability, and multiple comorbidities often exclude patients from curative treatment. Developments using the drugs lenalidomide, decitabine, and azacitidine have offered treatment options to patients ineligible for transplantation. Nurses remain instrumental in the administration, patient monitoring, and patient education associated with these new therapies.
authors.affiliation: James Cancer Hospital and Solove Research Institute, Ohio State University, Columbus, USA. melissa.lindsey@osumc.edu
authors.forename: Melissa
authors.initials: M
authors.lastname: Lindsey
authors.forename: Jill
authors.initials: J
authors.lastname: Beavers
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016913:Blood Component Transfusion; D019175:DNA Methylation / Q000187:drug effects; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000145:classification / Q000175:diagnosis* / Q000628:therapy*; D033581:Stem Cell Transplantation
chemical_list: D000970:Antineoplastic Agents