title: Management of neonatal seizures.
abstract: Seizures in the newborn period constitute a medical emergency. Subtle seizures are the commonest type of seizures occurring in the neonatal period. Myoclonic seizures carry the worst prognosis in terms of long-term neurodevelopmental outcome. Hypoxic-ischemic encephalopathy is the most common cause of neonatal seizures. Multiple etiologies often co-exist in neonates and hence it is essential to rule out common causes such as hypoglycaemia, hypocalcemia, and meningitis before initiating specific therapy. A comprehensive evidence based approach for management of neonatal seizures has been described in this protocol.
authors.affiliation: Division of Neonatology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
authors.forename: Jeeva M
authors.initials: JM
authors.lastname: Sankar
authors.forename: Ramesh
authors.initials: R
authors.lastname: Agarwal
authors.forename: Ashok
authors.initials: A
authors.lastname: Deorari
authors.forename: Vinod K
authors.initials: VK
authors.lastname: Paul
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use; D001569:Benzodiazepines / Q000008:administration & dosage; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000175:diagnosis; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D007231:Infant, Newborn; D010634:Phenobarbital / Q000008:administration & dosage; D010672:Phenytoin / Q000008:administration & dosage; D011379:Prognosis; D012640:Seizures / Q000145:classification / Q000628:therapy*
chemical_list: D000927:Anticonvulsants; D001569:Benzodiazepines; D010672:Phenytoin; D010634:Phenobarbital