title: The long-term follow-up of accommodative esotropia in a population-based cohort of children.
abstract: OBJECTIVE
  To report refractive and surgical outcomes in a cohort of children with accommodative esotropia.
  
  
  METHODS
  Retrospective population-based cohort.
  
  
  METHODS
  All pediatric patients (<19 years) diagnosed with accommodative esotropia in Olmsted County, Minnesota, from January 1, 1975, to December 31, 1994.
  
  
  METHODS
  Medical records identified by the Rochester Epidemiology Project were reviewed for spectacle and surgical management.
  
  
  METHODS
  Rate of surgical intervention and discontinuation of spectacles for esotropia.
  
  
  RESULTS
  A total of 306 children with accommodative esotropia were diagnosed during the study years; 244 (80%) had fully accommodative esotropia (FAET) and 62 (20%) had partially accommodative esotropia (PAET). The Kaplan-Meier rate of discontinuing spectacles for strabismus in this population was 8% by 5 years after diagnosis, 20% by 10 years, and 37% by 20 years. Children born prematurely (P = 0.046) or with a greater initial hyperopic refractive error (P<0.001) were significantly less likely to become spectacle-free during the follow-up period. During a median follow-up of 9.8 years (range, 0-27.9 years), 33 (13.5%) of the 244 subjects with FAET eventually underwent strabismus surgery. Male gender (P = 0.039) and an earlier age at onset (P = 0.008) and diagnosis (P<0.001) of FAET were associated with a higher likelihood of requiring surgery.
  
  
  CONCLUSIONS
  The majority of children with accommodative esotropia in this population continued to require spectacle correction into their second decade of life. A small proportion of children with FAET required surgical intervention, which was more likely to occur among boys and in those with an earlier age at onset and diagnosis of their deviation.
authors.affiliation: Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA. mohney@mayo.edu
authors.forename: Brian G
authors.initials: BG
authors.lastname: Mohney
authors.forename: Chrystia C
authors.initials: CC
authors.lastname: Lilley
authors.forename: Amy E
authors.initials: AE
authors.lastname: Green-Simms
authors.forename: Nancy N
authors.initials: NN
authors.lastname: Diehl
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004948:Esotropia / Q000503:physiopathology* / Q000628:therapy; D005139:Eyeglasses / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009801:Oculomotor Muscles / Q000601:surgery; D013508:Ophthalmologic Surgical Procedures; D012030:Refractive Errors / Q000503:physiopathology / Q000628:therapy; D012189:Retrospective Studies