Regio- and enantioselective iridium-catalyzed allylation of thiophenol: synthesis of enantiopure allyl phenyl sulfides.
A highly regio- and enantioselective allylic alkylation of sodium thiophenoxide has been realized by [Ir(COD)Cl](2)/phosphoramidite along with CsF as an additive, producing highly enantioenriched allyl phenyl sulfide compounds with up to 99% ee.
Zheng
Shengcai
S
Department of Chemistry, Tongji University, 1239 Siping Road, Shanghai 200092, P. R. China.
Gao
Ning
N
Liu
Wei
W
Liu
Dongge
D
Zhao
Xiaoming
X
Cohen
Theodore
T