title: Ipsilateral areolar hyperpigmentation following unilateral application of estradiol spray.
abstract: A 48 year old postmenopausal female noted hyperpigmentation of the left areola 3 months after beginning estradiol spray to her left forearm. She then applied the spray to the right forearm instead until the areolae were the same color again and then applied 1 spray to each forearm thereafter.
authors.affiliation: Dermatology Program, University of Texas Southwestern Austin Programs, Austin, TX, USA.
authors.forename: Dayna G
authors.initials: DG
authors.lastname: Diven
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Crawford
mesh_terms: D000279:Administration, Cutaneous; D004958:Estradiol / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D009558:Nipples / Q000187:drug effects*
chemical_list: D004958:Estradiol