title: Lupus pernio with multiple bone cysts in the fingers.
abstract: A 32-year-old Japanese man presented with a 3-year history of purple reddish, and painful swelling of his fingers along with indurated erythema on his nose and ears. He was diagnosed as having sarcoidosis 8 years prior because of uveitis and bilateral hilar lymphadenopathy. X-rays of the hands revealed multiple cystic lesions in the phalanges. Histological examination of the ear revealed epithelioid cell granulomas in the dermis. Oral prednisolone 20 mg/day improved his finger swelling and pain; however, his finger deformities and erythema remain unchanged. Bone involvement is sometimes seen in sarcoidosis and the hands are the most frequently affected areas. The frequency of bone involvement is higher in lupus pernio in comparison with other types of skin sarcoidosis. Systemic corticosteroids could be the first choice of treatment to relieve the symptoms.
authors.affiliation: Department of Dermatology, Gunma University Graduate School of Medicine, Maebashishi, Gunma, Japan. yanagai@showa.gunma-u.ac.jp
authors.forename: Yayoi
authors.initials: Y
authors.lastname: Nagai
authors.forename: Naoya
authors.initials: N
authors.lastname: Igarashi
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishikawa
mesh_terms: D000328:Adult; D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D005385:Fingers / Q000000981:diagnostic imaging / Q000473:pathology*; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D010146:Pain / Q000209:etiology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011859:Radiography; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D011239:Prednisolone