title: Percutaneous aortic valve replacement in a 65-year old patient with thalassemia intermedia: A case report.
abstract: Thalassaemia is an inherited hemoglobin disorder resulting in chronic hemolytic anemia. Organ damage caused by iron overload represents the major cause of illness and the heart complications secondary to extensive myocardial iron overload are the leading cause of mortality. These patients are generally not considered as candidates for heart transplantation. We report a case of a patient with thalassemia intermedia (TI) with severe cardiac dysfunction and severe aortic stenosis who underwent percutaneous aortic valve replacement (PARV). PARV was a safe and a valid therapeutic approach dramatically to improve the clinical evolution of cardiomyopathies in our patient.
authors.affiliation: Department of Thalassemia, S. Bambino Hospital, Catania, Italy. linarosso@gmail.com
authors.forename: Rosamaria
authors.initials: R
authors.lastname: Rosso
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Ussia
authors.forename: Benedetta
authors.initials: B
authors.lastname: Ximenes
authors.forename: Corrado
authors.initials: C
authors.lastname: Tamburino
authors.forename: Turiddu
authors.initials: T
authors.lastname: Lombardo
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000473:pathology*; D001024:Aortic Valve Stenosis / Q000150:complications / Q000628:therapy*; D002309:Cardiology / Q000379:methods*; D009202:Cardiomyopathies / Q000628:therapy; D006350:Heart Valve Prosthesis; D006801:Humans; D019190:Iron Overload / Q000628:therapy; D008297:Male; D009206:Myocardium / Q000473:pathology; D016896:Treatment Outcome; D017086:beta-Thalassemia / Q000150:complications / Q000628:therapy*