title: Association between metabolic syndrome and periodontal disease.
abstract: BACKGROUND
  Metabolic syndrome has been suggested as a potential risk factor for periodontal disease. Data based on NHANES III, with 7431 subjects aged 20 years or older, were analysed to confirm the association between metabolic syndrome and periodontal disease, and identify which components of metabolic syndrome might play a role in this association.
  
  
  METHODS
  Clinical criteria for metabolic syndrome included: (1) abdominal obesity; (2) increased triglycerides; (3) decreased HDL cholesterol; (4) hypertension or current use of hypertension medication; and (5) high fasting plasma glucose. Periodontal disease was evaluated by probing pocket depth (PPD) and was defined as mean PPD≥2.5 mm.
  
  
  RESULTS
  Women with two or more metabolic components had significantly increased odds of having periodontal disease as compared to those with no component [(two components, OR=5.6 (95% CI: 2.2-14.4); three or more, OR=4.7 (2.0-11.2)]. Using the definition of metabolic syndrome as having three to five metabolic components (reference group with <3 components), the adjusted odds ratios were 1.0 (0.7-1.6) for men and 2.1 (1.2-3.7) for women. Abdominal obesity was the largest contributory factor in both genders.
  
  
  CONCLUSIONS
  While the association between metabolic syndrome and periodontal disease was particularly significant for women, abdominal obesity appeared to be the contributing metabolic factor for both genders.
authors.affiliation: Center for Clinical Research and Health Promotion, School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico. oelisoa.andriankaja@gmail.com
authors.forename: O M
authors.initials: OM
authors.lastname: Andriankaja
authors.forename: S
authors.initials: S
authors.lastname: Sreenivasa
authors.forename: R
authors.initials: R
authors.lastname: Dunford
authors.forename: E
authors.initials: E
authors.lastname: DeNardin
mesh_terms: D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use; D008076:Cholesterol, HDL / Q000097:blood; D004522:Educational Status; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D015228:Hypertriglyceridemia / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D017058:Mexican Americans / Q000706:statistics & numerical data; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000453:epidemiology; D010510:Periodontal Diseases / Q000453:epidemiology*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000959:Antihypertensive Agents; D008076:Cholesterol, HDL