title: Doubling of water intake increases daytime blood pressure and reduces vertigo in healthy subjects.
abstract: We studied the effect of increased water intake on ambulatory blood pressure (BP) in healthy individuals. Blood pressure was recorded after 2 weeks of either regular (RWI) or extra water intake (EWI, an additional 30 ml water/kg body weight per day) in 20 healthy subjects (10 males, 10 females). The extra water intake (RWI: 1.7 ± 0.59 l, EWI: 3.7 ± 0.84 l, respectively, p < 0.0001, i.e., an increase of 2 liters) induced an increase in mean arterial daytime BP from 89.0 ± 5.5 mmHg during RWI to 91.4 ± 6.4 mmHg during the EWI phase (p = 0.005), while night-time BP was unchanged by the intervention. The visual-analogue-scale (VAS, maximum score of 10) score corresponding to the statement "I often experience vertigo" was 3.1 ± 2.6 during RWI and decreased to 2.1 ± 2. 1 during EWI phase (p = 0.008). In conclusion,two liters of extra water intake for 2 weeks significantly increased daytime blood pressure and reduced a sense of vertigo in healthy individuals.
authors.affiliation: Department of Medical and Health Sciences, Faculty of Health Sciences, University Hospital of Linkoping, Linkoping, Sweden.
authors.forename: Anders
authors.initials: A
authors.lastname: Jormeus
authors.forename: Samuel
authors.initials: S
authors.lastname: Karlsson
authors.forename: Christina
authors.initials: C
authors.lastname: Dahlgren
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Lindström
authors.forename: Fredrik H
authors.initials: FH
authors.lastname: Nystrom
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory; D016022:Case-Control Studies; D004326:Drinking / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D010507:Periodicity; D012107:Research Design; D016896:Treatment Outcome; D014717:Vertigo / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control; D055815:Young Adult