Review ofactinic keratosis. Part I: etiology, epidemiology and clinical presentation.
Clinically, actinic keratoses (solar keratoses) are keratotic lesions that occur on chronically sunlight-exposed skin. Histologically, they are epidermal tumors. Presenting with a spectrum of clinical features, actinic keratoses are believed to be predictors and precursors of invasive squamous cell carcinoma. This, the first of a two-part overview, examines the etiology and epidemiology of actinic keratoses, their clinical and histological features and their role in the development of nonmelanoma skin cancer.
Goldberg
Leonard H
LH
DermSurgery Associates, Houston, TX, USA. goldb1@dermsurgery.org
Mamelak
Adam J
AJ
D006801:Humans; D055623:Keratosis, Actinic / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D027383:Papillomaviridae; D012867:Skin / Q000473:pathology; D015595:Skin Aging; D013472:Sunlight; D014466:Ultraviolet Rays