title: Computational modeling of a new thrombectomy device for the extraction of blood clots.
abstract: Thrombectomy devices have been developed as an alternative means for clot removal. A number of devices using a variety of methods to remove the clot are now available. This chapter covers the analysis and research into a device recently developed in the UK, called a "GP" thrombus aspiration device (TAD). Presented in this work is the development of a model of this device, as well as its simulation and interpretation of the results obtained with the potential for helping in optimizing its operation for future use. The simulation model that is presented can be used in showing the potential performance of the "GP" TAD device under different conditions of blood flow and size of blood clot, obtaining the minimum pressure necessary to extract the clot and to check that both this pressure and the time required to complete the operation are reasonable for potential use in clinical situations patients, and are in line with experimentally obtained data.
authors.affiliation: Universidad Politecnica de Madrid, C. Jose Gutierrez Abascal 2, 28006 Madrid, Spain. gregorio.romero@upm.es
authors.forename: G
authors.initials: G
authors.lastname: Romero
authors.forename: I
authors.initials: I
authors.lastname: Higuera
authors.forename: M L
authors.initials: ML
authors.lastname: Martinez
authors.forename: G
authors.initials: G
authors.lastname: Pearce
authors.forename: N
authors.initials: N
authors.lastname: Perkinson
authors.forename: C
authors.initials: C
authors.lastname: Roffe
authors.forename: J
authors.initials: J
authors.lastname: Wong
mesh_terms: D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D019295:Computational Biology; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D018056:Hemorheology; D006801:Humans; D008955:Models, Cardiovascular; D017131:Thrombectomy / Q000295:instrumentation*; D013927:Thrombosis / Q000503:physiopathology / Q000601:surgery*