title: Upper urinary tract infections are associated with RANTES promoter polymorphism.
abstract: We evaluated the association between MCP-1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES-403 G>A genotype frequencies showed that children carrying the RANTES-403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux.
authors.affiliation: Laboratory of Immunopathology and Molecular Biology of the Kidney, Department of Pediatrics Salus Pueri, University of Padua, Italy.
authors.forename: Sonia
authors.initials: S
authors.lastname: Centi
authors.forename: Susanna
authors.initials: S
authors.lastname: Negrisolo
authors.forename: Alejandra
authors.initials: A
authors.lastname: Stefanic
authors.forename: Elisa
authors.initials: E
authors.lastname: Benetti
authors.forename: Walburga
authors.initials: W
authors.lastname: Cassar
authors.forename: Liviana
authors.initials: L
authors.lastname: Da Dalt
authors.forename: Waifro
authors.initials: W
authors.lastname: Rigamonti
authors.forename: Pietro
authors.initials: P
authors.lastname: Zucchetta
authors.forename: Giovanni
authors.initials: G
authors.lastname: Montini
authors.forename: Luisa
authors.initials: L
authors.lastname: Murer
authors.forename: Lina
authors.initials: L
authors.lastname: Artifoni
mesh_terms: D018946:Chemokine CCL5 / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics*; D014552:Urinary Tract Infections / Q000235:genetics*
chemical_list: C483024:CCL5 protein, human; D018946:Chemokine CCL5