The usefulness of toluidine red unheated serum test in the diagnosis of HIV-negative neurosyphilis.
We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the indication of lumbar puncture in syphilitic patients and a reactive cerebrospinal fluid-TRUST is considered diagnostic to neurosyphilis.
Jiang
Ying
Y
Department of Neurology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
Chen
Xiaohong
X
Ma
Xiaomeng
X
Yang
Yu
Y
Peng
Fuhua
F
Hu
Xueqiang
X
D000372:Agglutination Tests / Q000379:methods; D000907:Antibodies, Bacterial / Q000097:blood* / Q000134:cerebrospinal fluid*; D001391:Azo Compounds; D016009:Chi-Square Distribution; D006801:Humans; D007958:Leukocyte Count; D009494:Neurosyphilis / Q000175:diagnosis* / Q000382:microbiology; D011935:Reagins / Q000097:blood / Q000134:cerebrospinal fluid; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013588:Syphilis Serodiagnosis / Q000379:methods*; D014210:Treponema pallidum / Q000302:isolation & purification*
D000907:Antibodies, Bacterial; D001391:Azo Compounds; D011935:Reagins; C037318:toluidine red