title: A case of anaphylactic reaction following matsutake mushroom ingestion: demonstration of histamine release reaction of basophils.
abstract: BACKGROUND
  Matsutake mushroom is not recognized as a common food allergen. However, several case reports have suggested that this mushroom can induce anaphylaxis on rare occasions.
  
  
  METHODS
  We report a woman with bronchial asthma, who experienced two episodes of Matsutake-induced anaphylaxis. Both the prick-to-prick test and basophil histamine release test showed positive reactions to this mushroom in this patient, but not in control subjects.
  
  
  CONCLUSIONS
  Matsutake mushroom can, on rare occasions, cause anaphylaxis in sensitized people, a reaction so far observed only in Japan. Not ony the in vivo prick-to-prick test but also the in vitro basophil activation test utilizing the patient's blood represent useful methods for allergen identification and also for identification of sensitized subjects.
authors.affiliation: Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Takako
authors.initials: T
authors.lastname: Toda
authors.forename: Masao
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nakase
authors.forename: Naoya
authors.initials: N
authors.lastname: Sugimoto
authors.forename: Maho
authors.initials: M
authors.lastname: Suzukawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nagase
authors.forename: Ken
authors.initials: K
authors.lastname: Ohta
mesh_terms: D000328:Adult; D000363:Agaricales / Q000276:immunology*; D000707:Anaphylaxis; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000008:administration & dosage / Q000276:immunology; D052179:Antigens, Plant / Q000008:administration & dosage / Q000276:immunology; D001249:Asthma / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D001491:Basophils / Q000276:immunology; D002675:Child, Preschool; D003888:Desensitization, Immunologic; D004435:Eating; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D006632:Histamine / Q000378:metabolism; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D039981:Pyroglyphidae / Q000276:immunology; D014581:Urticaria
chemical_list: D039741:Antigens, Dermatophagoides; D052179:Antigens, Plant; D007073:Immunoglobulin E; D006632:Histamine