title: [Proteolytic control of expression of Vibrio fischeri lux-operon genes in Escherichia coli cells].
abstract: The key elements of the regulatory system activating expression of the lux-operon genes in the sea bacteria Vibrio fischeri are the LuxR protein (an activator oftranscription) and N-(3-oxohexanoyl) L-homoserine lactone (an autoinducer, AI). It is shown that the ATP-dependent proteases ClpXP and Lon take part in the negative control of expression of the lux-operon genes and that AI protects the LuxR protein from proteolysis.
authors.forename: O E
authors.initials: OE
authors.lastname: Mel'kina
authors.forename: I V
authors.initials: IV
authors.lastname: Manukhov
authors.forename: G B
authors.initials: GB
authors.lastname: Zavil'gel'skiĭ
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000494:pharmacology; D048908:Aliivibrio fischeri / Q000378:metabolism*; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D049071:Endopeptidase Clp / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics; D005798:Genes, Bacterial; D009154:Mutation; D009876:Operon; D049070:Protease La / Q000235:genetics; D018085:Regulon
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; C030654:N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone; D049070:Protease La; C483573:ClpXP protease, E coli; D049071:Endopeptidase Clp; D015107:4-Butyrolactone