Aptamer-induced self-assembly of a NIR-emissive platinum(II) terpyridyl complex for label- and immobilization-free detection of lysozyme and thrombin.
With the aptamer-induced self-assembly feature of NIR-emissive platinum(ii) terpyridyl complex, a "proof-of-principle" concept in label- and immobilization-free probing strategies of lysozyme and thrombin has been demonstrated with good selectivity and specificity.
Yeung
Margaret Ching-Lam
MC
Institute of Molecular Functional Materials (Areas of Excellence Scheme, University Grants Committee, Hong Kong) and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
Wong
Keith Man-Chung
KM
Tsang
Yuk Kai Tiu
YK
Yam
Vivian Wing-Wah
VW
D052157:Aptamers, Nucleotide / Q000378:metabolism*; D015374:Biosensing Techniques / Q000379:methods*; D004800:Enzymes, Immobilized / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D009113:Muramidase / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D009944:Organoplatinum Compounds / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013379:Substrate Specificity; D013917:Thrombin / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism
D052157:Aptamers, Nucleotide; D004800:Enzymes, Immobilized; D009944:Organoplatinum Compounds; D009113:Muramidase; D013917:Thrombin