title: Clinical effectiveness of alginate silver dressing in outpatient management of partial-thickness burns.
abstract: Askina Calgitrol Ag(®) (B. Braun Hospicare Ltd, Collooney Co. Sligo, Ireland), alginate silver wound dressing, is an advanced wound dressing which combines the potent broad-spectrum antimicrobial action of silver with enhanced exudate management properties of calcium alginate and polyurethane foam. The purpose of this study was to compare the efficacy of Askina Calgitrol Ag(®) and 1% silver sulfadiazine (1% AgSD) in the outpatient management of partial-thickness burn wounds at Burn Unit, Siriraj Hospital. A prospective descriptive study was conducted between January 2008 and January 2009 in Burn Unit, Division of Trauma Surgery, Siriraj Hospital, Mahidol University, Thailand. The 65 patients with partial-thickness burn wounds, less than 24 hours post-burn injury, had a total body surface area (TBSA%) less than 15% were treated at Siriraj Outpatient Burn Clinic. All patients were divided into Askina Calgitrol Ag(®) treated group (30 patients) and 1% AgSD treated group (35 patients). The data were compared by the demographics including age, gender, % TBSA burn, pain score, number of wound dressing change, nursing time and time of wound healing. Patients included in both groups were comparable with no significant differences in demographic data of age, gender, location of burn and type of burn injury (P > 0·05 evaluated by paired Student's t-test) between both group. The present results showed that average pain scores in the Askina Calgitrol Ag(®) treated group were significantly lower than the 1% AgSD treated group (2·23 ± 1·87 versus 6·08 ± 2·33, respectively) between both groups (P < 0·02). Patients treated with Askina Calgitrol Ag(®) had significantly lower number of wound dressing change (P < 0·02) and nursing time (P < 0·02) compared with 1% AgSD treated group. The Askina Calgitrol Ag(®) group needed less frequent wound dressing. Healing time was 7 ± 3·51 days after the application of Askina Calgitrol Ag(®). This was significantly shorter than that of control wounds (14 ± 4·18 days). Application of Askina Calgitrol Ag(®) leads to a good burn wound outcome. The present study confirms the effectiveness of Askina Calgitrol Ag(®) in the outpatient management of partial-thickness burn wounds.
authors.affiliation: Division of Trauma Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. anne surgeon@hotmail.com
authors.forename: Supaporn
authors.initials: S
authors.lastname: Opasanon
authors.forename: Pornprom
authors.initials: P
authors.lastname: Muangman
authors.forename: Nantaporn
authors.initials: N
authors.lastname: Namviriyachote
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000464:Alginates / Q000627:therapeutic use*; D000553:Ambulatory Care / Q000379:methods*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001458:Bandages; D002056:Burns / Q000150:complications / Q000473:pathology / Q000628:therapy*; D016009:Chi-Square Distribution; D015400:Clinical Nursing Research; D005260:Female; D020723:Glucuronic Acid / Q000627:therapeutic use; D006603:Hexuronic Acids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D010147:Pain Measurement; D011140:Polyurethanes; D011446:Prospective Studies; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D017592:Skin Care / Q000379:methods / Q000451:nursing; D013785:Thailand; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000464:Alginates; D000891:Anti-Infective Agents, Local; D006603:Hexuronic Acids; D011140:Polyurethanes; D020723:Glucuronic Acid; D012837:Silver Sulfadiazine