title: Clinical application of intermittent pressure-augmented retrograde cerebral perfusion.
abstract: Brain protection is important during aortic arch surgery, especially in patients with cerebral ischemia. We clinically applied the effectiveness of a novel protocol of retrograde cerebral perfusion with intermittent pressure augmentation for brain protection in a canine model, as described in a previous report. Although, in our patient the brachiocephalic artery and left subclavian artery were occluded as a result of aortitis, there was a history of right cerebral infarction, recovery of consciousness, and no neurologic sequelae. Near-infrared oximetry showed recovery of intracranial blood oxygen saturation every time the pressure was augmented.
authors.affiliation: Department of Cardiovascular Surgery, Kyorin University, Tokyo, Japan. kub@ks.kyorin-u.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kubota
authors.forename: Shinichi
authors.initials: S
authors.lastname: Takamoto
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yoshino
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kitahori
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kawata
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Tonari
authors.forename: Hidehito
authors.initials: H
authors.lastname: Endo
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuchiya
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Inaba
authors.forename: Yu
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sudo
mesh_terms: D000328:Adult; D001013:Aorta, Thoracic / Q000601:surgery*; D001921:Brain / Q000098:blood supply*; D002545:Brain Ischemia / Q000517:prevention & control*; D013504:Cardiovascular Surgical Procedures; D005260:Female; D006801:Humans; D010092:Oximetry; D010477:Perfusion / Q000379:methods*; D019265:Spectroscopy, Near-Infrared; D013625:Takayasu Arteritis / Q000601:surgery*