title: Intradural clinoidectomy and postoperative headache in patients undergoing aneurysm surgery.
abstract: BACKGROUND
  The incidence of severe, chronic postoperative headache in patients undergoing elective surgery for unruptured aneurysms is unknown. In addition, no clear risk factors have been identified for the development of postoperative headache.
  
  
  OBJECTIVE
  To evaluate intradural drilling of the anterior clinoid process as a mechanism for the development of postoperative headache after open aneurysm repair.
  
  
  METHODS
  A retrospective review of 128 patients undergoing open surgical treatment for unruptured, proximal carotid aneurysms treated at the University of Texas Southwestern Medical Center between January 2004 and December 2007. Patients who required intradural drilling of the anterior clinoid process were compared with patients in whom additional drilling was not necessary. The presence of postoperative headache and the duration and severity were noted.
  
  
  RESULTS
  In 28% of patients who underwent surgery with intradural clinoidectomy severe headache developed vs 7% of patients without clinoidectomy. This result was statistically significant (P < .05, Fisher exact test).
  
  
  CONCLUSIONS
  Intradural drilling of the anterior clinoid process was associated with an increased incidence of postoperative headache compared with no resection. This implicates either the dural manipulation necessary to expose the clinoid and optic strut or the introduction of bone dust into the subarachnoid space as potential risk factors for postoperative headache.
authors.affiliation: Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8855, USA. samuel.barnett@gmail.com
authors.forename: Samuel L
authors.initials: SL
authors.lastname: Barnett
authors.forename: Brett
authors.initials: B
authors.lastname: Whittemore
authors.forename: Jerri
authors.initials: J
authors.lastname: Thomas
authors.forename: Duke
authors.initials: D
authors.lastname: Samson
mesh_terms: D000328:Adult; D000368:Aged; D003399:Craniotomy / Q000009:adverse effects*; D004388:Dura Mater / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology*; D006322:Heart Aneurysm / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors