title: Use of self-expanding intracranial stents in the treatment of acute ischemic stroke.
abstract: Conventional endovascular therapy for acute ischemic stroke includes intraarterial pharmacologic thrombolysis with tissue plasminogen activator (TPA) administration with or without mechanical thrombectomy with a variety of devices. The present report describes two cases of stroke refractory to TPA administration in which successful recanalization was accomplished by the use of a self-expanding intracranial stent. Stent-assisted recanalization may be a viable option for patients with acute ischemic stroke refractory to thrombolysis or thrombectomy.
authors.affiliation: Department of Diagnostic Imaging, Rhode Island Hospital, Warren Alpert School of Medicine at Brown University, Providence, RI 02903, USA. eprince@lifespan.org
authors.forename: Ethan A
authors.initials: EA
authors.lastname: Prince
authors.forename: Mahesh V
authors.initials: MV
authors.lastname: Jayaraman
authors.forename: Richard A
authors.initials: RA
authors.lastname: Haas
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D002533:Cerebral Angiography; D057510:Endovascular Procedures / Q000295:instrumentation*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D015607:Stents; D020521:Stroke / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator