Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies.
This report introduces a framework for comparing radiotherapy treatment planning in multicentric in silico clinical trials. Quality assurance, data incompatibility, transfer and storage issues, and uniform analysis of results are discussed. The solutions that are given provide a useful guide for the set-up of future multicentric planning studies or public repositories of high quality data.
Roelofs
Erik
E
Department of Radiation Oncology (MAASTRO), Maastricht University Medical Centre, The Netherlands.
Persoon
Lucas
L
Qamhiyeh
Sima
S
Verhaegen
Frank
F
De Ruysscher
Dirk
D
Scholz
Michael
M
Iancu
Gheorghe
G
Engelsman
Martijn
M
Rasch
Coen
C
Zijp
Lambert
L
Meerleer
Gert De
GD
Coghe
Marc
M
Langendijk
Johannes
J
Schilstra
Cornelis
C
Pijls-Johannesma
Madelon
M
Lambin
Philippe
P
D002986:Clinical Trials as Topic; D006801:Humans; D015337:Multicenter Studies as Topic; D011785:Quality Assurance, Health Care; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods / Q000592:standards*