title: Functional cardiac MR imaging with true fast imaging with steady-state free precession before and after intravenous injection of contrast medium: comparison of image quality and accuracy.
abstract: OBJECTIVE
  To compare image quality and accuracy of left ventricular function of cine SSFP (steady-state free precession) images before and after injection of Gd-DTPA.
  
  
  METHODS
  In 30 patients T1 times of LV blood and myocardium were measured before and after injection of 0.2 mmol/kg body weight Gd-DTPA. Signal intensity of myocardium and left ventricular blood were measured on SSFP images and the contrast calculated. In 20 additional patients short axis images completely covering the left ventricle were acquired before and after injection of Gd-DTPA and parameters of left ventricular function compared. Image quality and regional function were assessed using the 17-segment model.
  
  
  RESULTS
  Image quality after injection of contrast medium did not significantly change compared with unenhanced images. Contrast between myocardium and LV blood decreased from 0.6 ± 0.01 to 0.4 ± 0.03 after injection while the T1 value of myocardium decreased from 1121 ± 21 ms to 389 ± 14 ms (blood 1413 ± 48 ms to 222 ± 8 ms). Assessment of regional and global left ventricular function revealed similar results before and after the injection of contrast medium.
  
  
  CONCLUSIONS
  Cine SSFP can be obtained after injection of contrast medium without loss of accuracy for regional and global LV ventricular function. This protocol can be used to decrease imaging time for thorough cardiac examination.
authors.affiliation: Department of Diagnostic Radiology, University Hospital, RWTH Aachen, Aachen, Germany. gabriele.krombach@uniklinikum-giessen.de
authors.forename: Gabriele A
authors.initials: GA
authors.lastname: Krombach
authors.forename: Thorsten
authors.initials: T
authors.lastname: Plum
authors.forename: Ralf
authors.initials: R
authors.lastname: Koos
authors.forename: Rainer
authors.initials: R
authors.lastname: Hoffmann
authors.forename: Ertunc
authors.initials: E
authors.lastname: Altiok
authors.forename: Nils A
authors.initials: NA
authors.lastname: Krämer
authors.forename: Rolf W
authors.initials: RW
authors.lastname: Günther
authors.forename: Felix
authors.initials: F
authors.lastname: Schoth
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000494:pharmacology*; D005260:Female; D019786:Gadolinium DTPA / Q000494:pharmacology*; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D015588:Observer Variation; D016277:Ventricular Function, Left
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA