title: Translational defects in a mutant deficient in YajL, the bacterial homolog of the parkinsonism-associated protein DJ-1.
abstract: We report here that YajL is associated with ribosomes and interacts with many ribosomal proteins and that a yajL mutant of Escherichia coli displays decreased translation accuracy, as well as increased dissociation of 70S ribosomes into 50S and 30S subunits after oxidative stress.
authors.affiliation: Stress Molecules, Institut Jacques Monod, Université Paris 7, 2 Place Jussieu, Paris, France.
authors.forename: Fatoum
authors.initials: F
authors.lastname: Kthiri
authors.forename: Valérie
authors.initials: V
authors.lastname: Gautier
authors.forename: Hai-Tuong
authors.initials: HT
authors.lastname: Le
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Prère
authors.forename: Olivier
authors.initials: O
authors.lastname: Fayet
authors.forename: Abderrahim
authors.initials: A
authors.lastname: Malki
authors.forename: Ahmed
authors.initials: A
authors.lastname: Landoulsi
authors.forename: Gilbert
authors.initials: G
authors.lastname: Richarme
mesh_terms: D004926:Escherichia coli / Q000378:metabolism / Q000502:physiology*; D029968:Escherichia coli Proteins; D014176:Protein Biosynthesis; D012269:Ribosomal Proteins / Q000172:deficiency*; D012270:Ribosomes / Q000378:metabolism
chemical_list: D029968:Escherichia coli Proteins; D012269:Ribosomal Proteins; C554198:YajL protein, E coli