[Clinical significance of cellular immune function in patients with viral myocarditis].
OBJECTIVE
To probe into the clinical significance of cellular immune function in patients with viral myocarditis.


METHODS
Choose our hospital in January 2008-December 2009 admitted during the 75 patients of viral myocarditis as the experimental group, 67 healthy patients served as control groups, respectively, and hospital admission within 24 h after the venous blood, before and after treatment T cell subsets, natural killer cells (NK) activity and tumor necrosis factor (TNF) were detected and analyzed.


RESULTS
Compared with admission, 24 h after admission test in peripheral blood T lymphocyte subsets CD3, CD4, CD8 and CD4/CD8 were improved and CD3, CD4 and CD4/CD8 were statistically significant differences (P<0.05), but still slightly lower in the control group, while the difference was not statistically significant. At the same time, compared with admission, 24 h after admission of natural killer cells in the experimental group (NK) and tumor necrosis factor were improved, the differences were statistically significant (P<0.05), but still slightly lower than the control group, but the difference was not statistically significant.


CONCLUSIONS
More in-depth study of viral myocarditis in patients with immune injury mechanism will help to better guide the treatment, and has important clinical significance.
Wen
Hong-ying
HY
The Affiliated Hospital, North Sichuan Medical College, Nanchong, China. why-1166@163.com
Jia
Wei-kun
WK
Liu
Li
L
Yang
Ling
L
Yang
Yan
Y
Sun
Xue-mei
XM
Gou
Jing
J
Zhang
Xiao-yan
XY
Wei
Shu-liang
SL
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000097:blood / Q000276:immunology* / Q000821:virology*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000097:blood / Q000276:immunology; D055815:Young Adult
D014409:Tumor Necrosis Factor-alpha