title: Periprosthetic fracture fixation of the femur following total hip arthroplasty: a review of biomechanical testing.
abstract: BACKGROUND
  periprosthetic femoral fracture can occur following total hip arthroplasty. Fixation of these fractures are challenging due to the combination of fractured bone with an existing prosthesis. There are several clinical studies reporting the failure of fixation methods used for these fractures, highlighting the importance of further biomechanical studies in this area.
  
  
  METHODS
  the current literature on biomechanical models of periprosthetic femoral fracture fixation is reviewed. The methodologies involved in the experimental and computational studies of this fixation are described and compared.
  
  
  RESULTS
  areas which require further investigation are highlighted and the potential use of finite element analysis as a computational tool to test the current fixation methods is addressed.
  
  
  CONCLUSIONS
  biomechanical models have huge potential to assess the effectiveness of different fixation methods. Experimental in vitro models have been used to mimic periprosthetic femoral fracture fixation however, the numbers of measurements that are possible in these studies are relatively limited due to the cost and data acquisition constraints. Computer modelling and in particular finite element analysis is a complimentary method that could be used to examine existing protocols for the treatment of periprosthetic femoral fracture and, potentially, find optimum fixation methods for specific fracture types.
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK. M.Moazen@Leeds.ac.uk
authors.forename: Mehran
authors.initials: M
authors.lastname: Moazen
authors.forename: Alison C
authors.initials: AC
authors.lastname: Jones
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Jin
authors.forename: Ruth K
authors.initials: RK
authors.lastname: Wilcox
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Tsiridis
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D001696:Biomechanical Phenomena; D002102:Cadaver; D003198:Computer Simulation; D005264:Femoral Fractures / Q000601:surgery; D005269:Femur / Q000503:physiopathology*; D020342:Finite Element Analysis; D005592:Fracture Fixation / Q000295:instrumentation* / Q000379:methods*; D050723:Fractures, Bone / Q000503:physiopathology; D006622:Hip Prosthesis; D006801:Humans; D057068:Periprosthetic Fractures / Q000503:physiopathology*; D015203:Reproducibility of Results