title: A validation study of the Italian Short-Form Leeds Dyspepsia Questionnaire.
abstract: Assessment of symptoms should be one of the main outcome measures in dyspepsia clinical trials. This requires a reliable, valid and responsive questionnaire that measures the frequency and severity of dyspeptic symptoms. The Short-Form Leeds Dyspepsia Questionnaire (SF-LDQ) has been proven to fulfil these criteria in its original version in the English language. The aim of the study was to assess the internal consistency, reliability, validity and responsiveness of the Italian version of the SF-LDQ in primary and secondary care. Unselected primary and secondary care patients completed the Italian version of the SF-LDQ. Test-retest reliability was assessed after 2 days. Validity was measured by comparison with diagnosis made by physicians. Responsiveness was determined before and after treatment for endoscopically proven disease. The SF-LDQ was administered to 311 patients in primary care and 179 in secondary care patients. Internal consistency, as judged by the Cronbach's α, was 0.90. Pearson's correlation coefficient for test-retest reliability was 0.92. The SF-LDQ had a sensitivity of 80% and a specificity of 82%. A highly significant response to change was also observed (p = 0.001). The Italian SF-LDQ is a reliable, valid and responsive self-completed outcome measure for quantifying the frequency and severity of dyspeptic symptoms.
authors.affiliation: Gastroenterology and Endoscopy Unit, Versilia Hospital, Lido di Camaiore, Italy. gattaluigi@yahoo.it
authors.forename: Luigi
authors.initials: L
authors.lastname: Gatta
authors.forename: Paul
authors.initials: P
authors.lastname: Moayyedi
authors.forename: Cesare
authors.initials: C
authors.lastname: Tosetti
authors.forename: Nimish
authors.initials: N
authors.lastname: Vakil
authors.forename: Enzo
authors.initials: E
authors.lastname: Ubaldi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Barsanti
authors.forename: Giulia
authors.initials: G
authors.lastname: Fiorini
authors.forename: Valentina
authors.initials: V
authors.lastname: Castelli
authors.forename: Carlo
authors.initials: C
authors.lastname: Gargiulo
authors.forename: Paolo
authors.initials: P
authors.lastname: Lucarini
authors.forename: Maurizio
authors.initials: M
authors.lastname: Lera
authors.forename: Enkleda
authors.initials: E
authors.lastname: Kajo
authors.forename: Francesco
authors.initials: F
authors.lastname: Di Mario
authors.forename: Dino
authors.initials: D
authors.lastname: Vaira
mesh_terms: D000328:Adult; D004415:Dyspepsia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007558:Italy; D007803:Language Arts; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires