Reversible conduction failure in pharyngeal-cervical-brachial variant of Guillain-Barré syndrome.
In two patients with the pharyngeal-cervical-brachial variant (PCB) of Guillain-Barré syndrome (GBS), low amplitude distal compound muscle action potentials and partial motor conduction blocks normalized without development of excessive temporal dispersion within 4 weeks. Sensory nerve action potentials significantly improved in amplitude or, when absent, rapidly became recordable at follow-up. Besides axonal degeneration, PCB is characterized by reversible conduction failure in both motor and sensory fibers and is in the continuous spectrum of axonal GBS subtypes.
Capasso
Margherita
M
Department of Human Motor Sciences, University G. d'Annunzio, Chieti, Italy.
Notturno
Francesca
F
Manzoli
Claudia
C
Yuki
Nobuhiro
N
Uncini
Antonino
A
D000200:Action Potentials; D000368:Aged; D001132:Arm; D001369:Axons; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000145:classification / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D018908:Muscle Weakness; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009334:Neck Muscles / Q000503:physiopathology*; D009410:Nerve Degeneration; D009431:Neural Conduction; D011984:Sensory Receptor Cells; D012782:Shoulder