title: Bioactivities of a Ti surface ablated with a femtosecond laser through SBF.
abstract: Micro-patterns with deposited calcium/phosphorus (Ca/P) elements on a pure titanium (Ti) surface were synthesized in 2.5 x simulated body fluid (SBF) by femtosecond laser ablation, and their bioactivities were evaluated by co-culture with osteoblasts. Scanning electron microscope observation showed that a three-order roughness micro-pattern, which was composed of grooves, islands, holes and sub-micro-particles, was obtained, and the size of holes and islands was increased from 0.5 µm and 2 µm to 5 µm and 6 µm, respectively, gradually with the increase of laser fluence from 3.3 J cm(-2) to 12.5 J cm(-2). Irradiation of femtosecond lasers promoted the deposition of Ca/P on the surface of a Ti plate. The osteoblasts grew faster and extended more slender filopodia on the femtosecond laser-ablated surface than on a sand blast followed by an acid surface, which demonstrated that the micro-patterns with deposited Ca/P on the surface were favorable for osteoblasts' growth.
authors.affiliation: School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130, People's Republic of China.
authors.forename: Hongshui
authors.initials: H
authors.lastname: Wang
authors.forename: Chunyong
authors.initials: C
authors.lastname: Liang
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Changyi
authors.initials: C
authors.lastname: Li
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000737:chemistry*; D002118:Calcium / Q000737:chemistry; D018920:Coculture Techniques; D007834:Lasers; D051379:Mice; D010006:Osteoblasts / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure; D010710:Phosphates / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D010710:Phosphates; D014025:Titanium; D002118:Calcium