Inactivation of Escherichia coli by nanoparticulate zerovalent iron and ferrous ion.
The mechanism of Escherichia coli inactivation by nanoparticulate zerovalent iron (nZVI) and Fe(II) was investigated using reactive oxygen species (ROS) quenchers and probes, an oxidative stress assay, and microscopic observations. Disruption of cell membrane integrity and respiratory activity was observed under deaerated conditions [more disruption by nZVI than Fe(II)], and OH or Fe(IV) appears to play a role.
Kim
Jee Yeon
JY
WCU Program of Chemical Convergence for Energy & Environment, School of Chemical and Biological Engineering, Seoul National University, Daehak-dong, Seoul 151-742, South Korea.
Park
Hee-Jin
HJ
Lee
Changha
C
Nelson
Kara L
KL
Sedlak
David L
DL
Yoon
Jeyong
J
D000900:Anti-Bacterial Agents / Q000378:metabolism*; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism*; D005296:Ferrous Compounds / Q000378:metabolism*; D007477:Ions / Q000378:metabolism*; D050296:Microbial Viability; D053758:Nanoparticles; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species / Q000378:metabolism
D000900:Anti-Bacterial Agents; D005296:Ferrous Compounds; D007477:Ions; D017382:Reactive Oxygen Species