title: Predictors of moderate-severe functional limitation 2 and 5 years after revision total knee arthroplasty.
abstract: In patients who underwent revision TKA from 1993 to 2005 and responded to follow-up questionnaires 2 or 5 years postrevision TKA, we studied whether body mass index (BMI), comorbidity (measured by validated Deyo-Charlson index), sex, and age predict activity limitation 2 and 5 years after revision TKA. Overall moderate-severe activity limitation was defined as 2 or more activities (walking, stairs, rising chair) with moderate-severe limitation. Multivariable logistic regressions also adjusted for income, diagnosis, and distance from medical center and American Society of Anesthesiologists physical status score. The prevalence of overall moderate-severe activity limitation was high: 46.5% (677/1456) at 2 years and 50.5% (420/832) at 5 years postrevision TKA. At both 2 and 5 years of follow-up, BMI of 40 or higher, higher Deyo-Charlson score, female sex, and age greater than 80 years, each significantly predicted higher odds of moderate-severe overall activity limitation.
authors.affiliation: Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, Minnesota, USA.
authors.forename: Jasvinder A
authors.initials: JA
authors.lastname: Singh
authors.forename: Megan M
authors.initials: MM
authors.lastname: O'Byrne
authors.forename: W Scott
authors.initials: WS
authors.lastname: Harmsen
authors.forename: David G
authors.initials: DG
authors.lastname: Lewallen
mesh_terms: D000367:Age Factors; D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D015992:Body Mass Index; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology*; D007720:Knee Prosthesis; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012086:Reoperation; D012737:Sex Factors; D016896:Treatment Outcome