title: Floor-of-mouth metastasis in colorectal cancer.
abstract: Colorectal cancers have potential for lymphatic and hematogenous metastases. Surgery is the definitive treatment, but the prognosis can be improved with the addition of chemotherapy, radiotherapy or both. However, the incidence of recurrence, both local and distant, remains significant. Distant metastases occur most often in the liver and lung; however, metastases to bone, adrenals, lymph nodes, brain, skin and the oral region have been reported. Metastases to the oral region are uncommon and may occur in the oral soft tissues or jaw bones. The prognosis in such patients is usually very poor. We report a case of colorectal carcinoma with metastasis to the floor of the mouth. This is probably the first reported case of metastasis to the floor of the mouth in a patient with colorectal cancer.
authors.affiliation: Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.
authors.forename: Tejinder
authors.initials: T
authors.lastname: Singh
authors.forename: Usha
authors.initials: U
authors.lastname: Amirtham
authors.forename: C T
authors.initials: CT
authors.lastname: Satheesh
authors.forename: K C
authors.initials: KC
authors.lastname: Lakshmaiah
authors.forename: T M
authors.initials: TM
authors.lastname: Suresh
authors.forename: K Govind
authors.initials: KG
authors.lastname: Babu
authors.forename: C
authors.initials: C
authors.lastname: Ramachandra
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D009060:Mouth Floor / Q000473:pathology*; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D009944:Organoplatinum Compounds / Q000008:administration & dosage
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil