Rhino-orbitocerebral zygomycosis caused by Conidiobolus incongruus in an immunocompromised patient in Germany.
Mucorales (subphylum Mucoromycotina) are well-known agents of invasive mucormycosis, whereas Entomophthorales (subphylum Entomophthoromycotina) are rarely encountered in human diseases in temperate zones. Here we report a fatal case of invasive rhino-orbitocerebral entomophthoramycosis caused by Conidiobolus incongruus in a 78-year-old woman with myelodysplastic syndrome.
Wüppenhorst
Nicole
N
Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany. nicole.wueppenhorst@uniklinik-freiburg.de
Lee
Mi-Kyung
MK
Rappold
Elfriede
E
Kayser
Gian
G
Beckervordersandforth
Jan
J
de With
Katja
K
Serr
Annerose
A
D000368:Aged; D020092:Conidiobolus / Q000302:isolation & purification*; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D004660:Encephalitis / Q000150:complications* / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D020459:Genes, rRNA; D005858:Germany; D006257:Head / Q000000981:diagnostic imaging; D006651:Histocytochemistry; D006801:Humans; D016867:Immunocompromised Host; D008853:Microscopy; D008969:Molecular Sequence Data; D009190:Myelodysplastic Syndromes / Q000150:complications*; D054517:Orbital Cellulitis / Q000150:complications* / Q000382:microbiology; D012331:RNA, Fungal / Q000235:genetics; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D012220:Rhinitis / Q000150:complications* / Q000382:microbiology; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed; D020096:Zygomycosis / Q000175:diagnosis* / Q000473:pathology
D004271:DNA, Fungal; D004275:DNA, Ribosomal; D012331:RNA, Fungal; D012337:RNA, Ribosomal, 18S