title: Intermediate Results of the Prestige LP Cervical Disc Replacement: Clinical and Radiological Analysis With Minimum Two-Year Follow-up.
abstract: METHODS
  prospective study.
  
  
  OBJECTIVE
  present results of Prestige LP artificial cervical disc replacement (ADR).
  
  
  BACKGROUND
  motion preservation with ADR can potentially reduce adjacent segment degeneration. METHODS.: Forty patients with 59 Prestige LP ADR were analyzed. Cervical range of motion, Neck Disability Index, Visual Analogue, Short Form-36, Modified American Academy of Orthopedic Surgeons, and Japanese Orthopedic Association scores and radiographs were evaluated. Clinical results were compared with anterior cervical discectomy and fusion.
  
  
  RESULTS
  there were 21 females and 19 males. Mean age was 43.9 years. Mean follow-up was 2.9 years. Of the patients, 62.5% had single level replacement-mainly C56 level (56%); 52.5% had myelopathy and 47.5% radiculopathy; 50% of neural compression was due to herniated disc, 45% due to spondylosis, and 5% due to both. There was significant improvement in the American Academy of Orthopedic Surgeons and Visual Analogue scores (P < 0.05) at 6 months and 2 years. There was significant improvement in the Neck Disability Index from a mean of 42.2 preoperation to 16.4 at 6 months and 15.2 at 2 years (P < 0.05). The mean Japanese Orthopedic Association score improved significantly from 14.7 preoperation to 15.7 at 6 months and 15.6 at 2 years (P < 0.05). There was significant improvement in all aspects of the Short Form-36 scores except general health (P < 0.05) at 6 months and 2 years. There was no significant difference in the clinical outcomes between ADR and anterior cervical discectomy and fusion. Segmental alignment (mean 8°, 14°, and 13° lordotic at preoperation, 6 months, and 2 years postoperation, respectively) and global alignment (mean 15.7°, 16.2°, and 17.3° lordotic at preoperation, 6 months, and 2 years postoperation, respectively) were maintained. Dynamic radiographs showed significant segmental motion with a 6 month's mean motion of 11.1° and a 2-year mean motion of 13.9° (P < 0.05).
  
  
  CONCLUSIONS
  prestige LP ADR showed significant improvement in clinical outcomes at 2 years. It restores segmental lordosis and preserves segmental motion up to 2 years postoperation.
authors.affiliation: Department of Orthopedic Surgery, Singapore General Hospital, Singapore. chanpeng99@gmail.com
authors.forename: Chan Wearn Benedict
authors.initials: CW
authors.lastname: Peng
authors.forename: Wai Mun
authors.initials: WM
authors.lastname: Yue
authors.forename: Abdul
authors.initials: A
authors.lastname: Basit
authors.forename: Chang Ming
authors.initials: CM
authors.lastname: Guo
authors.forename: Benjamin Phak Boon
authors.initials: BP
authors.lastname: Tow
authors.forename: John Li Tat
authors.initials: JL
authors.lastname: Chen
authors.forename: Maran
authors.initials: M
authors.lastname: Nidu
authors.forename: William
authors.initials: W
authors.lastname: Yeo
authors.forename: Seang Beng
authors.initials: SB
authors.lastname: Tan
mesh_terms: D000293:Adolescent; D000328:Adult; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000601:surgery*; D007405:Intervertebral Disc Displacement / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods*; D011446:Prospective Studies; D011843:Radiculopathy / Q000601:surgery; D011859:Radiography; D016059:Range of Motion, Articular; D013118:Spinal Cord Diseases / Q000601:surgery; D055009:Spondylosis / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult