title: Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine.
abstract: A fluorescent nucleobase analogue, 7-aminoquinazoline-2,4-(1H,3H)-dione, is incorporated into a DNA oligonucleotide and senses mismatched pairing by displaying G-specific fluorescence enhancement.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0358, USA.
authors.forename: Yun
authors.initials: Y
authors.lastname: Xie
authors.forename: Tucker
authors.initials: T
authors.lastname: Maxson
authors.forename: Yitzhak
authors.initials: Y
authors.lastname: Tor
mesh_terms: D001483:Base Sequence; D006147:Guanine / Q000737:chemistry*; D008969:Molecular Sequence Data; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry*; D009841:Oligonucleotides / Q000235:genetics; D055620:Optical Phenomena; D013050:Spectrometry, Fluorescence
chemical_list: D009705:Nucleosides; D009841:Oligonucleotides; D006147:Guanine