title: 30-Month randomised clinical trial to evaluate the clinical performance of a nanofill and a nanohybrid composite.
abstract: OBJECTIVE
  To evaluate the clinical performance of a nanofill and a nanohybrid composite in restorations in occlusal cavities of posterior teeth in a randomised trial over 30 months.
  
  
  METHODS
  Forty-one adolescents participated in the study. The teeth were restored with a nanofill (Filtek Z350, 3M ESPE), a nanohybrid (Esthet-X, Dentsply); Filtek Z250 (3M ESPE) was used as a control. After 30 months, the restorations were evaluated in accordance with the US Public Health Service (USPHS) modified criteria. The McNemar and Friedman tests were used for statistical analysis, at a level of significance of 5%.
  
  
  RESULTS
  There were significant differences in the roughness of Filtek Z250 (p=0.008) and Filtek Z350 (p<0.001) when the four time periods (baseline, 6 months, 12 months and 30 months) were compared. There were significant differences in the marginal adaptation of Filtek Z250 (p=0.001), Filtek Z350 (p<0.001) and Esthet-X (p=0.011). Except for one of each composite restoration, all the modifications ranged from Alpha to Bravo. There were significant differences in the surface roughness (p=0.005) when the three composites were compared after 30 months.
  
  
  CONCLUSIONS
  The materials investigated showed acceptable clinical performance after 30 months. Long-term re-evaluations are necessary for a more detailed analysis of these composites (CEP: #1252).
authors.affiliation: Department of Restorative Dentistry, Federal University of Paraíba (UFPB), Cidade Universitária, João Pessoa, PB 58059-900, Brazil.
authors.forename: Ana Karina Maciel
authors.initials: AK
authors.lastname: de Andrade
authors.forename: Rosângela Marques
authors.initials: RM
authors.lastname: Duarte
authors.forename: Fábia Danielle Sales Cunha
authors.initials: FD
authors.lastname: Medeiros e Silva
authors.forename: André Ulisses Dantas
authors.initials: AU
authors.lastname: Batista
authors.forename: Kenio Costa
authors.initials: KC
authors.lastname: Lima
authors.forename: Maria Luíza dos Anjos
authors.initials: ML
authors.lastname: Pontual
authors.forename: Marcos Antonio Japiassú Resende
authors.initials: MA
authors.lastname: Montes
mesh_terms: D000293:Adolescent; D001641:Bicuspid / Q000473:pathology; D003116:Color; D003188:Composite Resins / Q000737:chemistry*; D003731:Dental Caries / Q000473:pathology / Q000628:therapy; D003736:Dental Cavity Lining; D003738:Dental Cements / Q000737:chemistry; D018772:Dental Marginal Adaptation; D003764:Dental Materials / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods*; D017220:Dentin-Bonding Agents / Q000737:chemistry; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D008297:Male; D008963:Molar / Q000473:pathology; D053761:Nanocomposites / Q000737:chemistry*; D012008:Recurrence; D019233:Retreatment; D013499:Surface Properties; D019228:Tooth Crown / Q000473:pathology; D016896:Treatment Outcome
chemical_list: C554641:Adper single bond 2; D003188:Composite Resins; D003738:Dental Cements; D003764:Dental Materials; D017220:Dentin-Bonding Agents; C466112:Esthet-X; C444701:Filtek Z250; D005899:Glass Ionomer Cements; C533204:filtek Z350; C067790:Vitrabond