KRAS mutational analysis for colorectal cancer. Application: pharmacogenomic.
KRAS mutational analysis is a genetic test used in clinical practice for determining the status of the KRAS gene (wild type or mutant) in tumors from patients with metastatic colorectal cancer (CRC). Persons whose tumors are wild type may respond to therapies cetuximab (Erbitux) or panitumumab (Vectibix).
Wang
Grace
G
Center for Translational and Policy Research on Personalized Medicine (TRANSPERS), University of California, San Francisco, USA.
Kelley
Robin K
RK
Gappnet