Electrophysiological correlates of rapid auditory and linguistic processing in adolescents with specific language impairment.
Brief tonal stimuli and spoken sentences were utilized to examine whether adolescents (aged 14;3-18;1) with specific language impairments (SLI) exhibit atypical neural activity for rapid auditory processing of non-linguistic stimuli and linguistic processing of verb-agreement and semantic constraints. Further, we examined whether the behavioral and electrophysiological indices for rapid auditory processing were correlated with those for linguistic processing. Fifteen adolescents with SLI and 15 adolescents with normal language met strict criteria for displaying consistent diagnoses from kindergarten through the eighth grade. The findings provide evidence that auditory processing for non-linguistic stimuli is atypical in a significant number of adolescents with SLI compared to peers with normal language and indicate that reduced efficiency in auditory processing in SLI is more vulnerable to rapid rates (200ms ISI) of stimuli presentation (indexed by reduced accuracy, a tendency for longer RTs, reduced N100 over right anterior sites, and reduced amplitude P300). Many adolescents with SLI displayed reduced behavioral accuracy for detecting verb-agreement violations and semantic anomalies, along with less robust P600s elicited by verb-agreement violations. The results indicate that ERPs elicited by morphosyntactic aspects of language processing are atypical in many adolescents with SLI. Additionally, correlational analyses between behavioral and electrophysiological indices of processing non-linguistic stimuli and verb-agreement violations suggest that the integrity of neural functions for auditory processing may only account for a small proportion of the variance in morphosyntactic processing in some adolescents.
Weber-Fox
Christine
C
Purdue University, Department of Speech, Language, and Hearing Sciences, Heavilon Hall, 500 Oval Drive, West Lafayette, IN 47907-2038, United States. weberfox@purdue.edu
Leonard
Laurence B
LB
Wray
Amanda Hampton
AH
Tomblin
J Bruce
JB
D000161:Acoustic Stimulation; D000293:Adolescent; D000704:Analysis of Variance; D001307:Auditory Perception / Q000502:physiology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D007806:Language Disorders / Q000503:physiopathology*; D007807:Language Tests; D008297:Male; D012044:Regression Analysis