title: Is there a relationship between physical performance and orchiectomy?
abstract: Bilateral orchiectomy is indicated for the treatment of patients with testicular cancer or advanced prostate tumours. The influence of hypogonadism on physical performance is still not known. The purpose of this work was to verify the effect of bilateral orchiectomy on physical performance. Sixteen rats were divided into two groups: Group 1 (Control), in which only skin incision and suture were made (n = 5) and Group 2, in which the rats were submitted to bilateral orchiectomy (n = 11). The animals ran on a treadmill at the speed of 20 m min(-1) until they were fatigued and felt once, during 10 s, when the experiment was interrupted. Time to running and weight of animals were verified. The results were compared using the Mann-Whitney test. There was no difference on time to running - minutes - (P = 0.14) and weight - grams - (P = 0.25) between the animals submitted to orchiectomy (100 ± 44 min and 359 ± 38 g) and the control Group (81 ± 40 min to run and 327 ± 25 g). Bilateral orchiectomy does not affect the physical performance of the rat.
authors.affiliation: Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. petroian@medicina.ufmg.br
authors.forename: Andy
authors.initials: A
authors.lastname: Petroianu
authors.forename: D F M
authors.initials: DF
authors.lastname: Veloso
authors.forename: L R
authors.initials: LR
authors.lastname: Alberti
authors.forename: J A
authors.initials: JA
authors.lastname: Figueiredo
authors.forename: F H O C
authors.initials: FH
authors.lastname: Rodrigues
mesh_terms: D000818:Animals; D005080:Exercise Test; D008297:Male; D009919:Orchiectomy; D010807:Physical Endurance; D051381:Rats; D017208:Rats, Wistar; D013739:Testosterone / Q000502:physiology*
chemical_list: D013739:Testosterone