Total synthesis of (±)-marinopyrrole A via copper-mediated N-arylation.
The total synthesis of the racemic form of the marine alkaloid marinopyrrole A is described. The characteristic 1,3'-bipyrrole core was constructed by a copper-mediated N-arylation process under microwave irradiation.
Kanakis
Argyrios A
AA
Aristotle University of Thessaloniki, Department of Organic Chemistry, Faculty of Chemistry, University Campus, 54124 Thessaloniki, Greece.
Sarli
Vasiliki
V
D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis*
D011758:Pyrroles; C528298:marinopyrrole A; D003300:Copper