title: Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.
abstract: Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.
authors.affiliation: Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada. keynany@yahoo.com
authors.forename: Yoav
authors.initials: Y
authors.lastname: Keynan
authors.forename: Jennifer
authors.initials: J
authors.lastname: Juno
authors.forename: Adrienne
authors.initials: A
authors.lastname: Meyers
authors.forename: T Blake
authors.initials: TB
authors.lastname: Ball
authors.forename: Anand
authors.initials: A
authors.lastname: Kumar
authors.forename: Ethan
authors.initials: E
authors.lastname: Rubinstein
authors.forename: Keith R
authors.initials: KR
authors.lastname: Fowke
mesh_terms: D000328:Adult; D000483:Alleles; D002170:Canada / Q000453:epidemiology; D016638:Critical Illness; D004196:Disease Outbreaks; D005260:Female; D006579:Heterozygote; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000472:pathogenicity*; D007251:Influenza, Human / Q000453:epidemiology / Q000235:genetics* / Q000503:physiopathology* / Q000821:virology; D008297:Male; D058873:Pandemics; D019713:Receptors, CCR5 / Q000235:genetics*; D017384:Sequence Deletion; D012720:Severity of Illness Index
chemical_list: D019713:Receptors, CCR5