[Genetic polymorphisms of susceptible genes associated with prostate cancer].
With the development of the human genome project, many scientists have initiated the detection of human gene sequences. Single nucleotide polymorphisms (SNP), as the third generation of heredity markers, are widely applied to the studies of the mechanism of human susceptibility to complex diseases and the design of individualized treatment. This article reviews the genetic susceptible genes associated with prostate cancer, focusing on the genetic polymorphisms of cytokine, receptors and enzymes related with prostate cancer. It also analyzes the existing problems in the treatment of prostate cancer.
Liu
Yan
Y
Laboratory of Prostate Diseases, Tianjin Institute of Urology, Tianjin 300211, China.
Xu
Yong
Y
D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide; D011471:Prostatic Neoplasms / Q000235:genetics*