title: Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies.
abstract: This report introduces a framework for comparing radiotherapy treatment planning in multicentric in silico clinical trials. Quality assurance, data incompatibility, transfer and storage issues, and uniform analysis of results are discussed. The solutions that are given provide a useful guide for the set-up of future multicentric planning studies or public repositories of high quality data.
authors.affiliation: Department of Radiation Oncology (MAASTRO), Maastricht University Medical Centre, The Netherlands.
authors.forename: Erik
authors.initials: E
authors.lastname: Roelofs
authors.forename: Lucas
authors.initials: L
authors.lastname: Persoon
authors.forename: Sima
authors.initials: S
authors.lastname: Qamhiyeh
authors.forename: Frank
authors.initials: F
authors.lastname: Verhaegen
authors.forename: Dirk
authors.initials: D
authors.lastname: De Ruysscher
authors.forename: Michael
authors.initials: M
authors.lastname: Scholz
authors.forename: Gheorghe
authors.initials: G
authors.lastname: Iancu
authors.forename: Martijn
authors.initials: M
authors.lastname: Engelsman
authors.forename: Coen
authors.initials: C
authors.lastname: Rasch
authors.forename: Lambert
authors.initials: L
authors.lastname: Zijp
authors.forename: Gert De
authors.initials: GD
authors.lastname: Meerleer
authors.forename: Marc
authors.initials: M
authors.lastname: Coghe
authors.forename: Johannes
authors.initials: J
authors.lastname: Langendijk
authors.forename: Cornelis
authors.initials: C
authors.lastname: Schilstra
authors.forename: Madelon
authors.initials: M
authors.lastname: Pijls-Johannesma
authors.forename: Philippe
authors.initials: P
authors.lastname: Lambin
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D015337:Multicenter Studies as Topic; D011785:Quality Assurance, Health Care; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods / Q000592:standards*