title: Cancer: miRNA addiction - depending on life's little things.
abstract: MicroRNAs (miRNAs) pleiotropically modulate gene expression in all cell types. Many miRNAs are overexpressed in tumors, and recent findings suggest that tumors can be 'addicted' to miRNA overexpression, yielding a possible therapeutic opportunity.
authors.affiliation: Genentech, South San Francisco, CA 94080, USA.
authors.forename: David
authors.initials: D
authors.lastname: Dornan
authors.forename: Jeff
authors.initials: J
authors.lastname: Settleman
mesh_terms: D015870:Gene Expression; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D009369:Neoplasms / Q000235:genetics*; D009857:Oncogenes
chemical_list: D035683:MicroRNAs