Unmasking a role for sex chromosomes in gene silencing.
Several sexually dimorphic phenotypes correlate with sex-chromosome dosage rather than with phenotypic sex. New research suggests that sex chromosome dimorphism helps to regulate gene silencing.
Maatouk
Danielle M
DM
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Capel
Blanche
B
D000818:Animals; D041321:Chromosomes, Human, X / Q000235:genetics; D041322:Chromosomes, Human, Y / Q000235:genetics; D004303:Dosage Compensation, Genetic; D005260:Female; D018628:Gene Dosage; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D020868:Gene Silencing; D006801:Humans; D008297:Male; D010641:Phenotype; D012727:Sex Characteristics; D012730:Sex Chromosomes / Q000235:genetics*; D019849:Sex Determination Processes; D051876:Sex-Determining Region Y Protein / Q000235:genetics
D051876:Sex-Determining Region Y Protein