The Meaning-Making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: a randomized controlled pilot study.
OBJECTIVE
This pilot study aimed to provide supportive evidence for the acceptability and usefulness of the Meaning-Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, and to provide estimates of parameters needed to design a full-scale study.


METHODS
A randomized controlled trial with 24 patients (12 experimental and 12 control) was conducted. Existential well-being (primary outcome), overall quality of life, distress, anxiety, depression and self-efficacy were measured.


RESULTS
Compared to the control group, patients in the experimental group had a better sense of meaning in life at one and three months post-intervention.


CONCLUSIONS
The MMi seems a promising intervention for advanced cancer patients, and a full randomized controlled trial is warranted to further investigate its efficacy.
Henry
Melissa
M
McGill University, Montreal, Quebec, Canada. henrymel@total.net
Cohen
S Robin
SR
Lee
Virginia
V
Sauthier
Philippe
P
Provencher
Diane
D
Drouin
Pierre
P
Gauthier
Philippe
P
Gotlieb
Walter
W
Lau
Susie
S
Drummond
Nancy
N
Gilbert
Lucy
L
Stanimir
Gerald
G
Sturgeon
Jeremy
J
Chasen
Martin
M
Mitchell
Julie
J
Huang
Lina Nuoxin
LN
Ferland
Mira-Klode
MK
Mayo
Nancy
N
D000223:Adaptation, Psychological; D001007:Anxiety / Q000523:psychology; D003863:Depression / Q000523:psychology; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000523:psychology*; D010865:Pilot Projects; D011594:Psychometrics; D011614:Psychotherapy, Brief; D011788:Quality of Life; D020377:Self Efficacy; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000523:psychology / Q000628:therapy; D011795:Surveys and Questionnaires; D016896:Treatment Outcome