Effect of purple sweet potato leaves consumption on exercise-induced oxidative stress and IL-6 and HSP72 levels.
The aim of this study was to evaluate the effects of purple sweet potato leaves (PSPL) consumption on oxidative stress markers in a healthy, nontrained, young male population after completing a running exercise protocol. A crossover design was applied, with 15 subjects participating in a two-step dietary intervention period. Each subject was given a high- (PSPL group) or low-polyphenol (control group) diet for 7 days with a 14-day washout period. After each dietary intervention period, all subjects performed 1 h of treadmill running at a speed corresponding to 70% of each subject's individual maximal oxygen uptake (Vo(2max)). Blood samples were taken before exercise and at 0, 1, and 3 h after exercise. Compared with the control group, PSPL consumption significantly increased plasma total polyphenols concentration and total antioxidant power (i.e., the ferric-reducing ability of plasma) in the PSPL group. The markers of oxidative damage, plasma TBARS and protein carbonyl, significantly decreased. Plasma IL-6 concentration also decreased. However, no significant difference was found in HSP72 levels between the two groups. These findings indicate that consuming a high-polyphenol diet for 7 days can modulate antioxidative status and decrease exercise-induced oxidative damage and pro-inflammatory cytokine secretion.
Chang
Wen-Hsin
WH
School of Nutrition and Health Sciences, Taipei Medical University, 250 Wu-Shing St., Taipei 110, Taiwan.
Hu
Shene-Pin
SP
Huang
Ying-Fen
YF
Yeh
Tzu-Shao
TS
Liu
Jen-Fang
JF
D000975:Antioxidants / Q000008:administration & dosage* / Q000378:metabolism; D015415:Biomarkers / Q000097:blood; D018592:Cross-Over Studies; D004032:Diet; D015444:Exercise; D005419:Flavonoids / Q000008:administration & dosage* / Q000097:blood; D050884:HSP72 Heat-Shock Proteins / Q000097:blood*; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D027723:Ipomoea batatas; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects*; D010101:Oxygen Consumption; D010636:Phenols / Q000008:administration & dosage* / Q000097:blood; D018515:Plant Leaves; D059808:Polyphenols; D050050:Protein Carbonylation; D012420:Running; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D013997:Time Factors
D000975:Antioxidants; D015415:Biomarkers; D005419:Flavonoids; D050884:HSP72 Heat-Shock Proteins; C508600:IL6 protein, human; D018836:Inflammation Mediators; D015850:Interleukin-6; D010636:Phenols; D059808:Polyphenols; D017392:Thiobarbituric Acid Reactive Substances