Combinatorial structure of genome rearrangements scenarios.
In genome rearrangement theory, one of the elusive questions raised in recent years is the enumeration of rearrangement scenarios between two genomes. This problem is related to the uniform generation of rearrangement scenarios and the derivation of tests of statistical significance of the properties of these scenarios. Here we give an exact formula for the number of double-cut-and-join (DCJ) rearrangement scenarios between two genomes. We also construct effective bijections between the set of scenarios that sort a component as well studied combinatorial objects such as parking functions, labeled trees, and prüfer codes.
Ouangraoua
Aïda
A
Department of Mathematics, Simon Fraser University, Burnaby, BC, Canada. Aida.Ouangraoua@inria.fr
Bergeron
Anne
A
D000465:Algorithms; D002874:Chromosome Mapping; D015321:Gene Rearrangement; D016678:Genome; D008957:Models, Genetic