title: Increased fluoro-deoxy-D-glucose uptake on positron emission tomography-computed tomography postbronchoalveolar lavage: a potential cause of radiologic misinterpretation.
abstract: Cytologic analysis of bronchoalveolar lavage (BAL) fluid is used for lung cancer diagnosis. We describe a patient with a history of rectal carcinoma who presented with a new lung mass. BAL was performed, with positron emission tomography-computed tomography the following day. There was mildly increased fluoro-deoxy-D-glucose uptake in areas of the lung parenchyma with new ground-glass opacification. This created ambiguity in staging, clarified 2 weeks later by a computed tomography showing complete resolution of the ground-glass opacity. Clinicians should be aware that BAL may cause increased pulmonary fluoro-deoxy-D-glucose uptake, making accurate radiologic interpretation problematic. We suggest that to optimize positron emission tomography-computed tomography, studies should not be performed within 24 hours of BAL.
authors.affiliation: Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland.
authors.forename: Sum
authors.initials: S
authors.lastname: Leong
authors.forename: Owen J
authors.initials: OJ
authors.lastname: O'Connor
authors.forename: Deirdre
authors.initials: D
authors.lastname: Doyle
authors.forename: Desmond M
authors.initials: DM
authors.lastname: Murphy
authors.forename: Michael M
authors.initials: MM
authors.lastname: Maher
mesh_terms: D018893:Bronchoalveolar Lavage; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000378:metabolism; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D005947:Glucose