title: The Meaning-Making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: a randomized controlled pilot study.
abstract: OBJECTIVE
  This pilot study aimed to provide supportive evidence for the acceptability and usefulness of the Meaning-Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, and to provide estimates of parameters needed to design a full-scale study.
  
  
  METHODS
  A randomized controlled trial with 24 patients (12 experimental and 12 control) was conducted. Existential well-being (primary outcome), overall quality of life, distress, anxiety, depression and self-efficacy were measured.
  
  
  RESULTS
  Compared to the control group, patients in the experimental group had a better sense of meaning in life at one and three months post-intervention.
  
  
  CONCLUSIONS
  The MMi seems a promising intervention for advanced cancer patients, and a full randomized controlled trial is warranted to further investigate its efficacy.
authors.affiliation: McGill University, Montreal, Quebec, Canada. henrymel@total.net
authors.forename: Melissa
authors.initials: M
authors.lastname: Henry
authors.forename: S Robin
authors.initials: SR
authors.lastname: Cohen
authors.forename: Virginia
authors.initials: V
authors.lastname: Lee
authors.forename: Philippe
authors.initials: P
authors.lastname: Sauthier
authors.forename: Diane
authors.initials: D
authors.lastname: Provencher
authors.forename: Pierre
authors.initials: P
authors.lastname: Drouin
authors.forename: Philippe
authors.initials: P
authors.lastname: Gauthier
authors.forename: Walter
authors.initials: W
authors.lastname: Gotlieb
authors.forename: Susie
authors.initials: S
authors.lastname: Lau
authors.forename: Nancy
authors.initials: N
authors.lastname: Drummond
authors.forename: Lucy
authors.initials: L
authors.lastname: Gilbert
authors.forename: Gerald
authors.initials: G
authors.lastname: Stanimir
authors.forename: Jeremy
authors.initials: J
authors.lastname: Sturgeon
authors.forename: Martin
authors.initials: M
authors.lastname: Chasen
authors.forename: Julie
authors.initials: J
authors.lastname: Mitchell
authors.forename: Lina Nuoxin
authors.initials: LN
authors.lastname: Huang
authors.forename: Mira-Klode
authors.initials: MK
authors.lastname: Ferland
authors.forename: Nancy
authors.initials: N
authors.lastname: Mayo
mesh_terms: D000223:Adaptation, Psychological; D001007:Anxiety / Q000523:psychology; D003863:Depression / Q000523:psychology; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000523:psychology*; D010865:Pilot Projects; D011594:Psychometrics; D011614:Psychotherapy, Brief; D011788:Quality of Life; D020377:Self Efficacy; D012959:Socioeconomic Factors; D013315:Stress, Psychological / Q000523:psychology / Q000628:therapy; D011795:Surveys and Questionnaires; D016896:Treatment Outcome