title: Structural influence of chiral tertiary aminonaphthol ligands on the asymmetric phenyl transfer to aromatic aldehydes.
abstract: A series of chiral tertiary aminonaphthol ligands were prepared from 2-naphthol, (S)-1-phenylethylamine, and aldehydes with diverse substituted groups. The results of asymmetric phenyl transfer to aromatic aldehydes catalyzed by these chiral ligands indicated that enantioselectivities were greatly influenced by the electronic and steric effects of the ligands.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Wei
authors.forename: Lu
authors.initials: L
authors.lastname: Yin
authors.forename: Haibin
authors.initials: H
authors.lastname: Luo
authors.forename: Xingshu
authors.initials: X
authors.lastname: Li
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D009284:Naphthols / Q000737:chemistry*; D055601:Organic Chemistry Phenomena; D010627:Phenethylamines / Q000737:chemistry*; D019800:Phenol / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D008024:Ligands; D009284:Naphthols; D010627:Phenethylamines; D019800:Phenol; C028405:2-naphthol