title: Chromatic VEP in children with congenital colour vision deficiency.
abstract: Visual evoked potentials to chromatic stimulus (cVEP) are believed to selectively test the parvocellular visual pathway which is responsible for processing information about colour. The aim was to evaluate cVEP in children with red-green congenital colour vision deficiency. VEP responses of 15 colour deficient children were compared to 31 children with normal colour vision. An isoluminant red-green stimulus composed of horizontal gratings was presented in an onset-offset manner. The shape of the waveform was studied, as well as the latency and amplitude of positive (P) and negative (N) waves. cVEP response did not change much with increased age in colour deficient children, whereas normative data showed changes from a predominantly positive to a negative response with increased age. A P wave was present in 87% of colour deficient children (and in 100% of children with normal colour vision), whereas the N wave was absent in a great majority of colour deficient children and was present in 80% of children with normal colour vision. Therefore, the amplitude of the whole response (N-P) decreased linearly with age in colour deficient children, whereas in children with normal colour vision it increased linearly. P wave latency shortened with increased age in both groups. cVEP responses differ in children with congenital colour vision deficiency compared to children with normal colour vision.
authors.affiliation: Eye Clinic, University Medical Centre, Grablovičeva 46, Ljubljana, Slovenia. manca.tekavcic-pompe@guest.arnes.si
authors.forename: Manca
authors.initials: M
authors.lastname: Tekavčič Pompe
authors.forename: Branka
authors.initials: B
authors.lastname: Stirn Kranjc
authors.forename: Jelka
authors.initials: J
authors.lastname: Brecelj
mesh_terms: D000293:Adolescent; D000375:Aging / Q000502:physiology / Q000523:psychology; D002648:Child; D003118:Color Perception / Q000502:physiology; D003119:Color Perception Tests / Q000379:methods; D003117:Color Vision Defects / Q000151:congenital / Q000175:diagnosis* / Q000503:physiopathology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D011601:Psychophysics; D011930:Reaction Time / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology