title: Inter-subject connectivity-based parcellation of a patch of cerebral cortex.
abstract: This paper presents a connectivity-based parcellation of the human post-central gyrus, at the level of the group of subjects. The dimension of the clustering problem is reduced using a set of cortical regions of interest determined at the inter-subject level using a surface-based coordinate system, and representing the regions with a strong connection to the post-central gyrus. This process allows a clustering based on criteria which are more reproducible across subjects than in an intra-subject approach. We obtained parcels relatively stable in localisation across subjects as well as homogenous and well-separated to each other in terms of connectivity profiles. To address the parcellation at the inter-subject level provides a direct matching between parcels across subjects. In addition, this method allows the identification of subject-specific parcels. This property could be useful for the study of pathologies.
authors.affiliation: CEA Saclay, Neurospin/LNAO, Bât 145, 91191 Gif-sur-Yvette cedex, France.
authors.forename: Pauline
authors.initials: P
authors.lastname: Roca
authors.forename: Alan
authors.initials: A
authors.lastname: Tucholka
authors.forename: Denis
authors.initials: D
authors.lastname: Rivière
authors.forename: Pamela
authors.initials: P
authors.lastname: Guevara
authors.forename: Cyril
authors.initials: C
authors.lastname: Poupon
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Mangin
mesh_terms: D000465:Algorithms; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D056324:Diffusion Tensor Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D009415:Nerve Net / Q000033:anatomy & histology*; D009434:Neural Pathways / Q000033:anatomy & histology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique