title: Age and sexual activity are risk factors for mesh exposure following transvaginal mesh repair.
abstract: OBJECTIVE
  This study is about evaluating safety and potential risk factors for complications following pelvic organ prolapse repair with the GYNECARE PROLIFT system.
  
  
  METHODS
  This is a prospective observational study (Canadian Task Force II-1) performed in a tertiary referral center. A total of 114 women with pelvic organ prolapse, POP-Q stage ≥ 2, underwent a pelvic floor repair that included Prolift.
  
  
  RESULTS
  During a mean follow-up time of 7 months there were six procedure failures (5.3%) and 14 mesh exposures (12.3%), more commonly on the anterior vaginal wall. Age was inversely related to the risk of having late mesh exposure (p = 0.02) with an odds ratio of 1.99 (95% confidence interval 1.10-3.59) for each decrease of 10 years in age. Late mesh exposure was significantly more common in sexually active patients (p = 0.016).
  
  
  CONCLUSIONS
  Prolift repair has a high anatomical success rate. Young age and sexual activity are risk factors for mesh exposure.
authors.affiliation: Centre for Advanced Reproductive Endosurgery, Sydney, Australia. mdykaufman@gmail.com
authors.forename: Yuval
authors.initials: Y
authors.lastname: Kaufman
authors.forename: Sony Sukhbir
authors.initials: SS
authors.lastname: Singh
authors.forename: Haifa
authors.initials: H
authors.lastname: Alturki
authors.forename: Alan
authors.initials: A
authors.lastname: Lam
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D004868:Equipment Failure; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000295:instrumentation / Q000379:methods; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012725:Sexual Behavior / Q000502:physiology*; D013526:Surgical Mesh / Q000009:adverse effects*; D016896:Treatment Outcome; D014621:Vagina / Q000601:surgery*