Changing epidemiology of human parvovirus 4 infection in sub-Saharan Africa.
Human parvovirus 4 infections are primarily associated with parenteral exposure in western countries. By ELISA, we demonstrate frequent seropositivity for antibody to parvovirus 4 viral protein 2 among adult populations throughout sub-Saharan Africa (Burkina Faso, 37%; Cameroon, 25%; Democratic Republic of the Congo, 35%; South Africa, 20%), which implies existence of alternative transmission routes.
Sharp
Colin P
CP
University of Edinburgh, Edinburgh, Scotland, UK.
Vermeulen
Marion
M
Nébié
Yacouba
Y
Djoko
Cyrille F
CF
LeBreton
Matthew
M
Tamoufe
Ubald
U
Rimoin
Anne W
AW
Kayembe
Patrick K
PK
Carr
Jean K
JK
Servant-Delmas
Annabelle
A
Laperche
Syria
S
Harrison
G L Abby
GL
Pybus
Oliver G
OG
Delwart
Eric
E
Wolfe
Nathan D
ND
Saville
Andrew
A
Lefrère
Jean Jacques
JJ
Simmonds
Peter
P
D000293:Adolescent; D000328:Adult; D017954:Africa South of the Sahara / Q000453:epidemiology; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002050:Burkina Faso / Q000453:epidemiology; D002163:Cameroon / Q000453:epidemiology; D036022:Capsid Proteins / Q000276:immunology; D002648:Child; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000453:epidemiology* / Q000821:virology*; D017992:Parvovirus / Q000276:immunology*; D013019:South Africa / Q000453:epidemiology; D055815:Young Adult
D000914:Antibodies, Viral; D036022:Capsid Proteins