Multiple band frequency analysis in a child of medial temporal lobe ganglioglioma.
We report a 1-year 6-month-old girl with ganglioglioma in the right medial temporal lobe who showed epileptic spasms in clusters. Spasms occasionally followed a dazed and fearful gaze. Interictal electroencephalography (EEG) showed diffuse bursts of slightly irregular high-voltage spikes and slow waves without hypsarrhythmia. The findings on ictal EEG, single-photon emission computed tomography, and F-18 fluorodeoxyglucose positron emission tomography indicated focus on the right medial temporal lobe. Ictal fast rhythmic activity analysis of scalp EEG by multiple band frequency analysis showed gamma rhythms at 65-80 Hz with a high spectral power around the tumor area. Epileptic spasms completely disappeared after tumor resection. These findings suggest that the cerebral cortex may be a source of epileptic spasms and indicate the possibility of usefulness of fast activity analysis in this condition.
Mizuno
Tomoko
T
Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry (NCNP), 4-1-1, Kodaira, Tokyo 187 8551, Japan.
Nakagawa
Eiji
E
Sakuma
Hiroshi
H
Saito
Yoshiaki
Y
Komaki
Hirofumi
H
Sugai
Kenji
K
Sasaki
Masayuki
M
Takahashi
Akio
A
Otsuki
Taisuke
T
Sakihara
Kotoe
K
Inagaki
Masumi
M
D001932:Brain Neoplasms / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D018303:Ganglioglioma / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007223:Infant; D013702:Temporal Lobe / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome