title: Unilateral vs bilateral total knee arthroplasty risk factors increasing morbidity.
abstract: Because surgeons are electing to perform simultaneous bilateral total knee arthroplasty (TKA), it is important to identify which patients are at increased risk. We performed a retrospective cohort analysis of 150 patients with unilateral TKA vs 150 patients with simultaneous bilateral TKA. The bilateral group demonstrated a 2.1 times greater mean overall complication rate as well as increased transfusion rates. Patients older than 70 years exhibited significantly higher complication rates. Having a preexisting pulmonary disorder in the bilateral cohort carried nearly a 3-fold risk of complications. Patients with body mass indices greater than 30 displayed a complication rate of 0.97 in the bilateral group as opposed to 0.44 in the control group. Our study demonstrated that age, body mass index, and a preexisting pulmonary disorder resulted in increased complications.
authors.affiliation: Department of Orthopaedic Surgery, University of Illinois, Chicago, Illinois, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Fabi
authors.forename: Vivek
authors.initials: V
authors.lastname: Mohan
authors.forename: Wayne M
authors.initials: WM
authors.lastname: Goldstein
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Dunn
authors.forename: Brian P
authors.initials: BP
authors.lastname: Murphy
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D001803:Blood Transfusion / Q000706:statistics & numerical data; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008171:Lung Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome