title: [Intrahospital mortality during acute exacerbations of COPD. Study EABPCO-CPHG of the College of the Lung specialists of General hospitals (CPHG)].
abstract: BACKGROUND
  The objective of the present study was to determine the in-hospital mortality rate in the EAPCO-CPHG cohort and to identify risk factors.
  
  
  METHODS
  All patients with COPD acute exacerbation admitted to the pneumology department of 68 French general hospitals between October 2006 and June 2007 were included in the EABPCO-CPHG cohort.
  
  
  RESULTS
  At discharge, vital status was known for 1817 patients. Forty-five patients died during their hospital stay, i.e., an in-hospital mortality rate of 2.5%. Mutivariate analysis identified age (OR=1.07 [1.03-1.11]), grade greater than 2 dyspnea in stable state (OR=3.77 [1.68-8.57]), and number of clinical signs of severity during the acute exacerbation (OR=1.36 [1.11-1.55]) as independent risk factors for in-hospital mortality.
  
  
  CONCLUSIONS
  In-hospital mortality in patients admitted to a pneumology department of a general hospital is quite low. Simple clinical criteria allow easy identification of at-risk patients and should enable management to be improved.
authors.affiliation: Service de pneumologie-soins intensifs respiratoires, centre hospitalier général d'Antibes, 06606 Antibes cedex, France. jeanmichelchavaillon@gmail.com
authors.forename: J-M
authors.initials: JM
authors.lastname: Chavaillon
authors.forename: L
authors.initials: L
authors.lastname: Lerousseau
authors.forename: P
authors.initials: P
authors.lastname: David
authors.forename: F
authors.initials: F
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: Lamour
authors.forename: A
authors.initials: A
authors.lastname: Beraud
authors.forename: C
authors.initials: C
authors.lastname: Sleiman
authors.forename: D
authors.initials: D
authors.lastname: Debieuvre
authors.forename: N
authors.initials: N
authors.lastname: Just
authors.forename: F
authors.initials: F
authors.lastname: Senechal
authors.forename: J
authors.initials: J
authors.lastname: Camuset
authors.forename: M
authors.initials: M
authors.lastname: Mornet
authors.forename: G
authors.initials: G
authors.lastname: Fesq
authors.forename: M
authors.initials: M
authors.lastname: Zureik
authors.forename: N
authors.initials: N
authors.lastname: Roche
authors.forename: F
authors.initials: F
authors.lastname: Blanchon
authors.forename: J
authors.initials: J
authors.lastname: Piquet
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000401:mortality*; D012307:Risk Factors