Notch signaling: filopodia dynamics confer robustness.
Though usually thought of as mediating communication between adjacent cells, Notch-Delta signaling can take place over a longer range through cellular processes known as 'filopodia'. A recent study shows how the dynamics of filopodia can confer robustness to Notch-Delta dependent patterning.
Milán
Marco
M
Institute of Molecular Cell Biology, Department of Biological Sciences, National University of Singapore, Singapore. marco.milan@irbbarcelona.org
Cohen
Stephen M
SM
D000818:Animals; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000502:physiology; D011554:Pseudopodia / Q000378:metabolism*; D051880:Receptors, Notch / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
D051880:Receptors, Notch