title: Combined model-based segmentation and elastic registration for accurate quantification of the aortic arch.
abstract: Accurate quantification of the morphology of vessels is important for diagnosis and treatment of cardiovascular diseases. We introduce a new approach for the quantification of the aortic arch morphology that combines 3D model-based segmentation with elastic image registration. The performance of the approach has been evaluated using 3D synthetic images and clinically relevant 3D CTA images including pathologies. We also performed a comparison with a previous approach.
authors.affiliation: Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg.
authors.forename: Andreas
authors.initials: A
authors.lastname: Biesdorf
authors.forename: Karl
authors.initials: K
authors.lastname: Rohr
authors.forename: Hendrik
authors.initials: H
authors.lastname: von Tengg-Kobligk
authors.forename: Stefan
authors.initials: S
authors.lastname: Wörz
mesh_terms: D000465:Algorithms; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D055119:Elastic Modulus; D006801:Humans; D008955:Models, Cardiovascular; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*