Ipsilateral areolar hyperpigmentation following unilateral application of estradiol spray.
A 48 year old postmenopausal female noted hyperpigmentation of the left areola 3 months after beginning estradiol spray to her left forearm. She then applied the spray to the right forearm instead until the areolae were the same color again and then applied 1 spray to each forearm thereafter.
Diven
Dayna G
DG
Dermatology Program, University of Texas Southwestern Austin Programs, Austin, TX, USA.
Crawford
Jessica M
JM
D000279:Administration, Cutaneous; D004958:Estradiol / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D009558:Nipples / Q000187:drug effects*
D004958:Estradiol