title: Outbreak of chikungunya fever, Dakshina Kannada District, South India, 2008.
abstract: The outbreak of chikungunya fever that surfaced in India during late 2005 has affected more than 1.56 million people, spread to more than 17 states/union territories, and is still ongoing. Many of these areas are dengue- and leptospirosis-endemic settings. We carried out a cross-sectional survey in one such chikungunya-affected location in Dakshina Kannada District of Karnataka State to estimate the magnitude of the epidemic and the proportion of chikungunya virus (CHIKV) infections that remained clinically inapparent. The seropositivity for CHIKV infection was 62.2%, and the attack rate of confirmed CHIK fever was 58.3%. The proportion of inapparent CHIKV infection was 6.3%. The increasing trend in the seropositivity and attack rate of CHIKV infection with age group was statistically significant. The present study is an indicator of the magnitude of the ongoing outbreak of CHIKV infection in India that started during 2005-2006.
authors.affiliation: Regional Medical Research Centre (Indian Council of Medical Research), Port Blair, Andaman and Nicobar Islands, India. sathyamanimunda@rediffmail.com
authors.forename: Sathya P
authors.initials: SP
authors.lastname: Manimunda
authors.forename: Attayur P
authors.initials: AP
authors.lastname: Sugunan
authors.forename: Subhodh K
authors.initials: SK
authors.lastname: Rai
authors.forename: Paluru
authors.initials: P
authors.lastname: Vijayachari
authors.forename: Ananganallur N
authors.initials: AN
authors.lastname: Shriram
authors.forename: Sameer
authors.initials: S
authors.lastname: Sharma
authors.forename: Nagarajan
authors.initials: N
authors.lastname: Muruganandam
authors.forename: Itta K
authors.initials: IK
authors.lastname: Chaitanya
authors.forename: Dev R
authors.initials: DR
authors.lastname: Guruprasad
authors.forename: Anakkathil B
authors.initials: AB
authors.lastname: Sudeep
mesh_terms: D000293:Adolescent; D000328:Adult; D018354:Alphavirus Infections / Q000453:epidemiology*; D000914:Antibodies, Viral / Q000097:blood; D002646:Chikungunya virus / Q000276:immunology; D002648:Child; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007194:India / Q000453:epidemiology; D008875:Middle Aged; D012621:Seasons; D016036:Seroepidemiologic Studies; D013997:Time Factors; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M