[Pathology of malignant lymphomas--clarity instead of confusion].
After decades of confusion in lymphoma classification clearness was achieved with the publication of the REAL classification 1994 and of the WHO classification 2001. The revised 4th edition 2008 features some additional new categories. The WHO classification comprises B- and T-lymphoblastic neoplasms, mature B-cell lymphomas, mature T-cell and NK-cell lymphomas and Hodgkin lymphomas. A modern diagnostic work-up of lymphomas is based on morphology, immunohistochemistry and increasingly on molecular studies. Last but not least the evaluation of all these findings by an expert haematopathologist, who collaborates closely with the treating clinicians, is essential. The aim is to give an overview of the most frequent mature B-cell lymphomas and the most important classical Hodgkin lymphomas with focus on morphology and immunohistochemistry.
Mueller-Garamvölgyi
Esther
E
Institut für Pathologie, Universität Bern, Bern. esther.mueller@pathology.unibe.ch
Perren
Aurel
A
Schmitt
Anja
A
D018450:Disease Progression; D006689:Hodgkin Disease / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D008224:Lymphoma, Follicular / Q000145:classification / Q000175:diagnosis / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse; D011379:Prognosis