title: Toward precise pulmonary nodule descriptors for nodule type classification.
abstract: A framework for nodule feature-based extraction is presented to classify lung nodules in low-dose CT slices (LDCT) into four categories: juxta, well-circumscribed, vascularized and pleural-tail, based on the extracted information. The Scale Invariant Feature Transform (SIFT) and an adaptation to Daugman's Iris Recognition algorithm are used for analysis. The SIFT descriptor results are projected to lower-dimensional subspaces using PCA and LDA. Complex Gabor wavelet nodule response obtained from an adopted Daugman Iris Recognition algorithm revealed improvements from the original Daugman binary iris code. This showed that binarized nodule responses (codes) are inadequate for classification since nodules lack texture concentration as seen in the iris, while the SIFT algorithm projected using PCA showed robustness and precision in classification.
authors.affiliation: Department of Electrical and Computer Engineering, University of Louisville Medical Imaging Division, Jewish Hospital, Louisville, KY, USA.
authors.forename: Amal
authors.initials: A
authors.lastname: Farag
authors.forename: Shireen
authors.initials: S
authors.lastname: Elhabian
authors.forename: James
authors.initials: J
authors.lastname: Graham
authors.forename: Aly
authors.initials: A
authors.lastname: Farag
authors.forename: Robert
authors.initials: R
authors.lastname: Falk
mesh_terms: D000465:Algorithms; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*