title: Developmental toxicity of selenium to Dolly Varden char (Salvelinus malma).
abstract: Gametes were collected from Dolly Varden char (Salvelinus malma) from waterbodies in a region exposed to mining-related selenium (Se) releases in British Columbia, Canada. Fertilized eggs were incubated in a laboratory and deformities were assessed on newly-hatched alevins using a graduated severity index. No effects were observed on egg or alevin survival or larval weight across the studied exposure range of 5.4 to 66 mg/kg dry weight in egg. Length of some larvae was reduced at the highest egg Se concentrations and a clear residue-response relationship was observed for larval deformity. The egg concentration corresponding to a 10% increase in the frequency of deformity (EC10) was 54 mg/kg dry weight, which is substantially higher than reported for other cold-water fish species.
authors.affiliation: Golder Associates, 500 - 4260 Still Creek Drive, Burnaby, British Columbia V5C 6C6, Canada. bgmcdonald@golder.com
authors.forename: Blair G
authors.initials: BG
authors.lastname: McDonald
authors.forename: Adrian M H
authors.initials: AM
authors.lastname: deBruyn
authors.forename: James R F
authors.initials: JR
authors.lastname: Elphick
authors.forename: Martin
authors.initials: M
authors.lastname: Davies
authors.forename: David
authors.initials: D
authors.lastname: Bustard
authors.forename: Peter M
authors.initials: PM
authors.lastname: Chapman
mesh_terms: D000818:Animals; D001955:British Columbia; D005260:Female; D008906:Mining; D017683:Oncorhynchus / Q000002:abnormalities* / Q000196:embryology; D012098:Reproduction / Q000187:drug effects; D012643:Selenium / Q000032:analysis / Q000506:poisoning*; D018675:Toxicity Tests / Q000379:methods; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000506:poisoning*
chemical_list: D014874:Water Pollutants, Chemical; D012643:Selenium