Comparison of pharyngeal stenosis between hypopharyngeal patients undergoing primary versus salvage laryngopharyngectomy.
OBJECTIVE
To survey the risk factors of pharyngeal stenosis after laryngopharyngectomy in patients with advanced hypopharyngeal cancers.


METHODS
Case series with chart review.


METHODS
Tertiary medical center.


METHODS
Pharyngeal stenosis rates and risk factors were compared between two groups of laryngopharyngectomy patients: a group that underwent concurrent chemoradiation therapy followed by surgical salvage, and a surgery initiated group with adjuvant chemoradiation.


RESULTS
Of 160 patients, 25 developed pharyngeal stenosis, which was diagnosed by barium esophagography with a pooling of barium contrast above the neopharyngeal inlet. These patients required nasogastric tube feeding or gastrostomy feeding because an oral liquid diet could not meet their nutritional needs. Primary closure and old age were risk factors for pharyngeal stenosis. Pharyngeal stenosis did not affect survival in patients with advanced hypopharyngeal cancer who underwent laryngopharyngectomy.


CONCLUSIONS
Primary closure reconstruction is discouraged in patients over the age of 65 years.
Tsou
Yung-An
YA
Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan.
Lin
Meng-Hung
MH
Hua
Chun-Hung
CH
Tseng
Hsien-Chang
HC
Bau
Da-Tian
DT
Tsai
Ming-Hsui
MH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D003251:Constriction, Pathologic / Q000209:etiology; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010611:Pharyngectomy / Q000009:adverse effects*; D010614:Pharynx / Q000473:pathology*; D012307:Risk Factors; D016879:Salvage Therapy; D013524:Surgical Flaps / Q000009:adverse effects; D015996:Survival Rate