title: Effect of an air cleaner with electrostatic filter on the removal of airborne house dust mite allergens.
abstract: OBJECTIVE
  The effects of air cleaners on the removal of airborne indoor allergens, especially house dust mites (HDM), are still controversial. The objective of this study is to evaluate the effect of an air cleaner with an electrostatic filter on the removal of airborne mite allergens.
  
  
  METHODS
  A dried HDM culture medium that contained mite body particles and excretions was dispersed in a chamber equipped with an electrostatic air cleaner. The number of airborne particles was recorded continuously by a dust spectrometer for 60 minutes. Airborne particles in the chamber were collected on a sampling filter at a flow rate of 10 L/min and the Der f 1 concentration in the filter extracts was measured by two-site ELISA.
  
  
  RESULTS
  The air cleaner efficiently removed airborne HDM particles. The air cleaner removed airborne HDM particles (size 2-12.5 µm) 11.4 ± 2.9 fold (cleaner operating for 15 minutes), 5.4 ± 0.7 fold (cleaner operating for 30 minutes), and 2.4 ± 0.2 fold (cleaner operating for 60 minutes) more than the removal of HDM particles by natural settle down. Removal kinetics differed according to the particle size of the airborne particles. The air cleaner decreased the concentration of Der f 1 in the extraction of airborne particles collected on the air sampling filter by 60.3%.
  
  
  CONCLUSIONS
  The electrostatic air cleaner can remove airborne HDM allergens and may be useful as a supplementary environmental control tool for HDM sensitized respiratory allergic patients.
authors.affiliation: Division of Allergy and Immunology, Institute of Allergy, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Santosh Rani
authors.initials: SR
authors.lastname: Agrawal
authors.forename: Hak-Joon
authors.initials: HJ
authors.lastname: Kim
authors.forename: Yong Won
authors.initials: YW
authors.lastname: Lee
authors.forename: Jung-Ho
authors.initials: JH
authors.lastname: Sohn
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Yong-Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Sung-Hwa
authors.initials: SH
authors.lastname: Lee
authors.forename: Chein-Soo
authors.initials: CS
authors.lastname: Hong
authors.forename: Jung-Won
authors.initials: JW
authors.lastname: Park
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D000485:Allergens / Q000032:analysis; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000032:analysis* / Q000276:immunology*; D003470:Culture Media / Q000378:metabolism; D004391:Dust / Q000032:analysis / Q000276:immunology; D004777:Environment; D004784:Environmental Monitoring / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005374:Filtration; D006801:Humans; D007700:Kinetics; D008925:Mites; D010316:Particle Size; D055672:Static Electricity
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D003470:Culture Media; D004391:Dust