Dinuclear Ni2-Schiff base complex-catalyzed asymmetric 1,4-addition of β-keto esters to nitroethylene toward γ(2,2)-amino acid synthesis.
A homodinuclear Ni(2)-Schiff base 1 complex (1-10 mol%) promoted the catalytic asymmetric 1,4-addition reactions of β-keto esters and an N-Boc oxindole to nitroethylene, giving products in 98-75% ee.
Mitsunuma
Harunobu
H
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.
Matsunaga
Shigeki
S
D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D005030:Ethylenes / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*; D013237:Stereoisomerism
D004952:Esters; D005030:Ethylenes; D007659:Ketones; D009574:Nitro Compounds; D009942:Organometallic Compounds; D012545:Schiff Bases; D009532:Nickel