title: Risk factors, management and outcome of subtypes of ischemic stroke: a stroke registry from the Arabian Gulf.
abstract: BACKGROUND
  Data on the determinants and outcome of ischemic stroke (IS) from the Arabian Gulf countries (AGC) are still scanty. The aim of this study was to characterize IS in six large stroke centers on the Arabian peninsula.
  
  
  METHODS
  IS subtypes were evaluated in four AGC from January 2006 to December 2007 in a large prospective multicenter hospital-based stroke registry including demographics, baseline risk factors, outcome and management.
  
  
  RESULTS
  A total of 780 patients with IS were included. Mean age was 58.9 years (63.7% males). Large-artery atherosclerosis (LAA) (38.1%) was the most common subtype followed by lacunar stroke (LS)(34.7%), cardioembolic stroke (CE)(13.5%) and other determined causes (7%). LAA and CE were both more commonly observed over the age of 70. LAA showed a higher male preponderance, and the highest prevalence of hypertension, diabetes, obesity and ischemic heart disease among all subtypes. Obesity was a risk factor for both LAA and CE. Anterior circulation stroke was significantly more affected in LAA (21.2%), CE (19%) and LS (15.1%) subtype of stroke than in posterior circulation strokes (4.4%, 2.9% and 2.8%, respectively) (p<0.05). Only 0.8% of patients received thrombolysis. The 90-day outcome was worst in LAA and least affected in LS. The over-all 90-day mortality was 2.1%.
  
  
  CONCLUSIONS
  Demographically, our data are different from those in Western registries but the distribution of stroke subtypes is comparable. Compared to Asian registries the ratio LS versus LAA was much lower. For the first time these data allow to study the IS profile in this population.
authors.affiliation: Department of Neurology (Medicine), Hamad Medical Corporation, Doha, Qatar. ddeleu@hmc.org.qa
authors.forename: Dirk
authors.initials: D
authors.lastname: Deleu
authors.forename: Jihad
authors.initials: J
authors.lastname: Inshasi
authors.forename: Naveed
authors.initials: N
authors.lastname: Akhtar
authors.forename: Jafer
authors.initials: J
authors.lastname: Ali
authors.forename: Thomas
authors.initials: T
authors.lastname: Vurgese
authors.forename: Shujauldin
authors.initials: S
authors.lastname: Ali
authors.forename: Manorama
authors.initials: M
authors.lastname: Rajan
authors.forename: Moudi
authors.initials: M
authors.lastname: AlMutairy
authors.forename: Ahmed
authors.initials: A
authors.lastname: Zayed
authors.forename: George
authors.initials: G
authors.lastname: Paulose
authors.forename: Kassid
authors.initials: K
authors.lastname: Nouri
authors.forename: Anil
authors.initials: A
authors.lastname: Thussu
authors.forename: Francisco Ruiz
authors.initials: FR
authors.lastname: Miyares
authors.forename: Tayseer
authors.initials: T
authors.lastname: Abdeen
authors.forename: Hassan
authors.initials: H
authors.lastname: AlHail
authors.forename: Asmahan
authors.initials: A
authors.lastname: Alshubaili
authors.forename: Hisham
authors.initials: H
authors.lastname: Mahmoud
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D018912:Arabs / Q000706:statistics & numerical data*; D002545:Brain Ischemia / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy