title: MhyADH catalysed Michael addition of water and in situ oxidation.
abstract: The Michael addition of water is a major challenge. Here an enzymatic approach is described. Interestingly, the enzyme (MhyADH) does not only catalyse the Michael addition of water but also the in situ oxidation of the product.
authors.affiliation: Gebouw voor Scheikunde, Afdeling Biotechnologie, Technische Universiteit Delft, Julianalaan 136, 2628 BL Delft, The Netherlands.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Jin
authors.forename: Philip C
authors.initials: PC
authors.lastname: Oskam
authors.forename: Sanjib K
authors.initials: SK
authors.lastname: Karmee
authors.forename: Adrie J J
authors.initials: AJ
authors.lastname: Straathof
authors.forename: Ulf
authors.initials: U
authors.lastname: Hanefeld
mesh_terms: D000426:Alcohol Dehydrogenase / Q000378:metabolism*; D020562:Betaproteobacteria / Q000201:enzymology; D055162:Biocatalysis; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry* / Q000378:metabolism
chemical_list: D014867:Water; D000426:Alcohol Dehydrogenase