title: Bone Metastasis as the Only Metastatic Site in a Patient with Pancreatic Cancer following Distal Pancreatectomy.
abstract: Pancreatic cancer remains a challenge both diagnostically and therapeutically. The typical sites of metastases in pancreatic cancer include the liver and peritoneum. Other less common sites are the lung, brain, kidney, and bone. Skeletal metastases are less prevalent in occurrence but contribute to significant morbidity associated with pancreatic cancer. The prevalence of osseous metastases remains unknown but has been estimated to be between 5% and 20%. The most common osseous lesions are osteolytic in nature, but the osteoblastic ones are extremely rare. Here, we report an interesting case of pancreatic adenocarcinoma with exclusive bone metastases and discuss briefly the possible pathogenesis.
authors.affiliation: Division of Hematology/Oncology, Department of Medicine, Columbia University College of Physicians and Surgeons, NY 10032, USA.
authors.forename: Muhammad Wasif
authors.initials: MW
authors.lastname: Saif
authors.forename: Natalie
authors.initials: N
authors.lastname: Galanina
authors.forename: L
authors.initials: L
authors.lastname: Ravage-Mass
authors.forename: Kristin
authors.initials: K
authors.lastname: Kaley
authors.forename: Daniel
authors.initials: D
authors.lastname: Cornfeld
authors.forename: Lynne
authors.initials: L
authors.lastname: Lamb
authors.forename: David
authors.initials: D
authors.lastname: Chhieng