title: Evaluation of inter-session 3D-TRUS to 3D-TRUS image registration for repeat prostate biopsies.
abstract: To ensure accurate targeting and repeatability, 3D TRUS-guided biopsies require registration to determine coordinate transformations to (1) incorporate pre-procedure biopsy plans and (2) compensate for inter-session prostate motion and deformation between repeat biopsy sessions. We evaluated prostate surface- and image-based 3D-to-3D TRUS registration by measuring the TRE of manually marked, corresponding, intrinsic fiducials in the whole gland and peripheral zone, and also evaluated the error anisotropy. The image-based rigid and non-rigid methods yielded the best results with mean TREs of 2.26 mm and 1.96 mm, respectively. These results compare favorably with a clinical need for an error of less than 2.5 mm.
authors.affiliation: Biomedical Engineering Graduate Program, The University of Western Ontario, London, ON, Canada N6A 5C1.
authors.forename: Vaishali V
authors.initials: VV
authors.lastname: Karnik
authors.forename: Aaron
authors.initials: A
authors.lastname: Fenster
authors.forename: Jeff
authors.initials: J
authors.lastname: Bax
authors.forename: Lori
authors.initials: L
authors.lastname: Gardi
authors.forename: Igor
authors.initials: I
authors.lastname: Gyacskov
authors.forename: Jacques
authors.initials: J
authors.lastname: Montreuil
authors.forename: Cesare
authors.initials: C
authors.lastname: Romagnoli
authors.forename: Aaron D
authors.initials: AD
authors.lastname: Ward
mesh_terms: D000465:Algorithms; D001706:Biopsy / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000379:methods*