A simple cladding process to apply monolithic silica rods in high performance liquid chromatography.
A simple cladding procedure was developed to apply monolithic silica rods in chromatography. This was used to evaluate the performances of new monolithic silica phases synthesised using a triblock copolymer as a phase separation inducer. The cladding procedure is found efficient after several tests, including scanning electron microscopy and mercury porosimetry, and the obtained columns present a relatively good efficiency in adsorption chromatography (H min is about 50 μm) as compared to other lab-scale developed columns.
Chamieh
Joseph
J
Laboratoire de Chimie Analytique et Sciences Séparatives, UMR 7178 IPHC-DSA, ECPM 25 rue Becquerel, 67087 Strasbourg Cedex, France. joseph.chamieh@univ-lyon1.fr
Zimmermann
Yvan
Y
Boos
Anne
A
Hagège
Agnès
A
D000327:Adsorption; D002846:Chromatography, Affinity / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D016018:Least-Squares Analysis; D008628:Mercury; D008855:Microscopy, Electron, Scanning; D010539:Permeability; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D013696:Temperature
D012822:Silicon Dioxide; D008628:Mercury