[Effects of compound Centella asiatica enema on kidneys coefficient, electrolytes and blood in chronic renal failure rats].
OBJECTIVE
To study the pharmacological effects of compound Centella asiatica enema on chronic renal failure (CRF) rats.


METHODS
Rats were divided into control group, CRF model group, Niaoduqing positive control group, compound Centella asiatica enema high, middle and low three groups kidney coefficient, electrolyte levels, hematocrit (HCT), red blood cell counts (RBC), hemoglobin (HGB) content were observed after 30 days's treatment.


RESULTS
Compared with the model group, the level of the electrolyte, HCT, RBC, HGB of rats in compound Centella asiatica enema high-doses group and the Niaoduqing group were significantly improved.


CONCLUSIONS
High-doses of compound Centella asiatica enema has significant therapeutic effect on CRF rats.
Pang
Lei-lei
LL
Southern Medical University Southern Hospital, Guangzhou 510515, China. leilei-p@126.com
Hou
Lian-bing
LB
Mei
Quang-xi
QX
Kong
Xiang-lian
XL
Hu
Ying
Y
Gao
Yu-qiao
YQ
Lin
Hui
H
Liu
Zhao-hui
ZH
Zeng
Cong-yan
CY
Lian
Yong-yin
YY
Zhang
Zu-rui
ZR
D000225:Adenine / Q000008:administration & dosage; D000818:Animals; D004195:Disease Models, Animal; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004573:Electrolytes / Q000097:blood*; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009929:Organ Size; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D004573:Electrolytes; D006454:Hemoglobins; D000225:Adenine