Real-time analysis of mucosal flora in patients with inflammatory bowel disease in India.
Mucosa-associated bacterial flora from control individuals and inflammatory bowel disease (IBD) patients were evaluated by real-time analysis using 16S rRNA-based genus-specific primers. Our data show a clear delineation in concentration of bacteria between the predominating and subdominating genera under disease conditions, indicating that the subsets of bacteria participating in the pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) are likely to be different.
Verma
Ravi
R
School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Verma
Anil Kumar
AK
Ahuja
Vineet
V
Paul
Jaishree
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D001419:Bacteria / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D058491:Bacterial Load; D044822:Biodiversity; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D006801:Humans; D007194:India; D015212:Inflammatory Bowel Diseases / Q000382:microbiology*; D007413:Intestinal Mucosa / Q000382:microbiology*; D008297:Male; D054892:Metagenome; D008875:Middle Aged; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D055815:Young Adult
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S