Analysis of the melanotrope cell neuroendocrine interface in two amphibian species, Rana ridibunda and Xenopus laevis: a celebration of 35 years of collaborative research.
This review gives an overview of the functioning of the hypothalamo-hypophyseal neuroendocrine interface in the pituitary neurointermediate lobe, as it relates to melanotrope cell function in two amphibian species, Rana ridibunda and Xenopus laevis. It primarily but not exclusively concerns the work of two collaborating laboratories, the Laboratory for Molecular and Cellular Neuroendocrinology (University of Rouen, France) and the Department of Cellular Animal Physiology (Radboud University Nijmegen, The Netherlands). In the course of this review it will become apparent that Rana and Xenopus have, for the most part, developed the same or similar strategies to regulate the release of α-melanophore-stimulating hormone (α-MSH). The review concludes by highlighting the molecular and cellular mechanisms utilized by thyrotropin-releasing hormone (TRH) to activate Rana melanotrope cells and the function of autocrine brain-derived neurotrophic factor (BDNF) in the regulation of Xenopus melanotrope cell function.
Jenks
Bruce G
BG
Department of Cellular Animal Physiology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands. b.jenks@science.ru.nl
Galas
Ludovic
L
Kuribara
Miyuki
M
Desrues
Laurence
L
Kidane
Adhanet H
AH
Vaudry
Hubert
H
Scheenen
Wim J J M
WJ
Roubos
Eric W
EW
Tonon
Marie-Christine
MC
D000818:Animals; D009074:Melanocyte-Stimulating Hormones / Q000378:metabolism*; D052717:Melanotrophs / Q000166:cytology* / Q000378:metabolism*; D055099:Neuroendocrine Cells / Q000166:cytology / Q000378:metabolism*; D011333:Pro-Opiomelanocortin / Q000378:metabolism; D011895:Rana ridibunda; D014982:Xenopus laevis
D011333:Pro-Opiomelanocortin; D009074:Melanocyte-Stimulating Hormones