Dietary exposure of juvenile common sole (Solea solea L.) to polybrominated diphenyl ethers (PBDEs): Part 1. Bioaccumulation and elimination kinetics of individual congeners and their debrominated metabolites.
The uptake and elimination of six PBDE congeners (BDE-28, -47, -99, -100, -153, -209) were studied in juvenile common sole (Solea solea L.) exposed to spiked contaminated food over a three-month period, then depurated over a five-month period. The results show that all of the studied PBDEs accumulate in fish tissues, including the higher brominated congener BDE-209. Several additional PBDE congeners were identified in the tissues of exposed fish, revealing PBDE transformation, mainly via debromination. The identified congeners originating from PBDE debromination include BDE-49 and BDE-202 and a series of unidentified tetra-, penta-, and hepta- BDEs. Contaminant assimilation efficiencies (AEs) were related to their hydrophobicity (log Kow) and influenced by PBDE biotransformation. Metabolism via debromination appears to be a major degradation route of PBDEs in juvenile sole in comparison to biotransformation into hydroxylated metabolites.
Munschy
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C
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Biogeochemistry of Organic Contaminants, Rue de l'Ile d'Yeu, BP 21105, 44311 Nantes Cedex 3, France. Electronic address: cmunschy@ifremer.fr.
Héas-Moisan
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K
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Biogeochemistry of Organic Contaminants, Rue de l'Ile d'Yeu, BP 21105, 44311 Nantes Cedex 3, France.
Tixier
C
C
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Biogeochemistry of Organic Contaminants, Rue de l'Ile d'Yeu, BP 21105, 44311 Nantes Cedex 3, France.
Olivier
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N
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Biogeochemistry of Organic Contaminants, Rue de l'Ile d'Yeu, BP 21105, 44311 Nantes Cedex 3, France.
Gastineau
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O
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Adaptation, Reproduction and Nutrition of marine fish, BP 70, 29280 Plouzané, France.
Le Bayon
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N
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Adaptation, Reproduction and Nutrition of marine fish, BP 70, 29280 Plouzané, France.
Buchet
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V
Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Laboratory of Adaptation, Reproduction and Nutrition of marine fish, BP 70, 29280 Plouzané, France.
D000818:Animals; D001711:Biotransformation; D004032:Diet; D004784:Environmental Monitoring; D005412:Flatfishes / Q000378:metabolism*; D055768:Halogenated Diphenyl Ethers / Q000378:metabolism*; D011075:Polybrominated Biphenyls / Q000378:metabolism
C477694:2,2',4,4',5-brominated diphenyl ether; D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; C517828:hexabrominated diphenyl ether 153; C511295:2,2',4,4'-tetrabromodiphenyl ether; C533760:tribromodiphenyl ether 28; C010902:decabromobiphenyl ether