A prospective study of bispectral index scoring in mentally retarded patients receiving general anesthesia.
OBJECTIVE
To determine whether degree of mental retardation (MR) affects bispectral index scale (BIS) scores during general anesthesia.


METHODS
Prospective clinical study.


METHODS
University Hospital.


METHODS
80 ASA physical status I, II and III patients with varying degrees of MR, undergoing dental rehabilitation.


METHODS
Patients were grouped into mild, moderate, severe or profound degrees of MR, by an independent registered research nurse according to criteria by the American Psychiatric Association.


METHODS
All patients were given a standard sevoflurane in oxygen anesthetic with ASA standard monitoring. A research assistant who was blinded to study group assignment recorded the BIS scores continuously on a computer and compared the scores at the following time points: awake, induction of anesthesia, intravenous catheter placement, tracheal intubation, start of surgery, end of surgery, awakening to commands, and tracheal extubation.


RESULTS
No significant differences in BIS scores existed among the study groups at any time point. No significant difference in slope of induction of anesthesia was noted among the study groups. However, the slope of emergence from anesthesia leading to tracheal extubation showed a significantly longer emergence time in the higher MR groups.


CONCLUSIONS
MR does not affect BIS values during general anesthesia.
Ponnudurai
Rex N
RN
Department of Anesthesiology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA. ponnudrn@umdnj.edu
Clarke-Moore
Andrea
A
Ekulide
Ifeyinwa
I
Sant
Manasee
M
Choi
Krissy
K
Stone
Justin
J
Spivack
Evan
E
Schoenberg
Catherine
C
Delphin
Ellise
E
D000293:Adolescent; D000328:Adult; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000627:therapeutic use; D002648:Child; D056805:Consciousness Monitors; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008607:Intellectual Disability / Q000150:complications* / Q000503:physiopathology; D007442:Intubation, Intratracheal / Q000379:methods*; D008297:Male; D008738:Methyl Ethers / Q000627:therapeutic use; D008875:Middle Aged; D019647:Oral Surgical Procedures / Q000379:methods*; D011446:Prospective Studies; D012720:Severity of Illness Index; D000077149:Sevoflurane; D013997:Time Factors; D055815:Young Adult
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane