title: Effects of a flexible alkyl chain on a ligand for CuAAC reaction.
abstract: Imidazole derivatives substituted by a normal alkyl group are shown to be efficient as a ligand for the copper(Ι)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. An alkyl chain on the imidazole ligands shows an efficient steric effect and benefits the reaction. Such functionalities of an alkyl chain allow a rapid CuAAC reaction of even a bulky alkyne, which has been difficult to perform under conventional conditions.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoutodaigaku-katsura, Nishikyo, Kyoto 615-8510, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Asano
authors.forename: Seijiro
authors.initials: S
authors.lastname: Matsubara