Boronic acid porphyrin receptor for ginsenoside sensing.
Ginsenoside detection was pursued through the design of a porphyrin receptor containing two boronic acid units. This receptor was found to undergo different degrees of fluorescence quenching with five ginsenoside guests and an acylated derivative. The trends in the 1:1 binding constants, as well as ESI-HRMS analysis, support a binding mode in which the ginsenoside sugar units are bound to the boronic acid groups, while the steroid core and porphyrin ring participate in hydrophobic interactions.
Hargrove
Amanda E
AE
Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-0165, United States.
Reyes
Ryan N
RN
Riddington
Ian
I
Anslyn
Eric V
EV
Sessler
Jonathan L
JL
D001897:Boronic Acids / Q000737:chemistry*; D036145:Ginsenosides / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*
D001897:Boronic Acids; D036145:Ginsenosides; D011166:Porphyrins