Five classic articles in somatic cell reprogramming.
Research on somatic cell reprogramming has progressed significantly over the past few decades, from nuclear transfer into frogs' eggs in 1952 to the derivation of human-induced pluripotent stem (iPS) cells in the present day. In this article, I review five landmark papers that have laid the foundation for current efforts to apply somatic cell reprogramming in the clinic.
Park
In-Hyun
IH
Department of Genetics, Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad 201B, New Haven, CT 06520, USA. inhyun.park@yale.edu
D065150:Cellular Reprogramming / Q000235:genetics / Q000502:physiology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000378:metabolism*