title: Diagnosis of cryptic chromosomal syndromes by fluorescence in situ hybridization (FISH).
abstract: This unit describes the various methods by which cytogeneticists detect chromosome abnormalities. The unit offers guidance for detecting such abnormalities with fluorescence in situ hybridization (FISH), as well as the benefits, limitations, and other applications of FISH.
authors.affiliation: Signature Genomic Laboratories, Spokane, Washington, USA.
authors.forename: Catherine D
authors.initials: CD
authors.lastname: Kashork
authors.forename: Aaron
authors.initials: A
authors.lastname: Theisen
authors.forename: Lisa G
authors.initials: LG
authors.lastname: Shaffer
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D002869:Chromosome Aberrations; D003582:Cytogenetics; D005826:Genetics, Medical; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D013577:Syndrome