title: DYW-type PPR proteins in a heterolobosean protist: plant RNA editing factors involved in an ancient horizontal gene transfer?
abstract: A particular type of pentatricopeptide repeat (PPR) proteins with variable length of the 35 aa PPR motifs and conserved carboxyterminal extensions, named the PLS proteins, was so far exclusively identified in land plants. Several PLS proteins with such domain extensions (E, E+, DYW) were shown to be involved in plant organellar RNA editing but their evolutionary origin had remained enigmatic. We here report the first case of DYW-type PLS proteins outside of the plant kingdom in the protist Naegleria gruberi and hypothesize on horizontal gene transfer in very early land plant evolution.
authors.affiliation: IZMB-Institut für Zelluläre und Molekulare Botanik, Abteilung Molekulare Evolution, Universität Bonn, Bonn, Germany. volker.knoop@uni-bonn.de
authors.forename: Volker
authors.initials: V
authors.lastname: Knoop
authors.forename: Mareike
authors.initials: M
authors.lastname: Rüdinger
mesh_terms: D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D022761:Gene Transfer, Horizontal; D008969:Molecular Sequence Data; D009253:Naegleria / Q000235:genetics*; D015388:Organelles / Q000235:genetics; D010802:Phylogeny; D015800:Protozoan Proteins / Q000145:classification / Q000235:genetics*; D017393:RNA Editing; D018749:RNA, Plant / Q000235:genetics; D020449:Repetitive Sequences, Amino Acid
chemical_list: D015800:Protozoan Proteins; D018749:RNA, Plant