[Cryptorchidism: from physiopathology to infertility].
Cryptorchidism is a defect of testicular descent. Hormonal, genetic and environmental factors might also contribute to the aetiology of cryptorchidism and its increased incidence in recent years in industrialised countries. Cryptorchidism itself might be considered a complex disease. This testicular pathology represents the best-characterized risk factor for reduced fertility and testicular cancer. The purpose of this review is to better understand physiopathology and mechanisms of infertility in men with history of cryptorchidism.
Robin
G
G
Service d'Andrologie, Hôpital Calmette, CHRU de Lille, avenue Oscar-Lambret, 59037 Lille cedex, France. geoffroy.robin@chru-lille.fr
Boitrelle
F
F
Marcelli
F
F
Colin
P
P
Leroy-Martin
B
B
Mitchell
V
V
Dewailly
D
D
Rigot
J-M
JM
D003456:Cryptorchidism / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D011247:Pregnancy; D012307:Risk Factors; D013736:Testicular Neoplasms / Q000209:etiology; D013737:Testis / Q000196:embryology; D013739:Testosterone / Q000097:blood
D013739:Testosterone