title: Lessons from total synthesis of hybrid natural products.
abstract: There are a vast number of interesting and useful compounds that are readily found in nature. Mother Nature has acquired ingenious ways of generating molecular diversity in living cells responsible for regulation of various biochemical events. This has inspired research into the synthesis of biologically active compounds for use as antibiotics or in cancer therapy, for example. This account provides an overview of the work performed in the total synthesis of hybrid natural products and the interesting synthetic mechanisms encountered along the way.
authors.affiliation: Department of Chemistry, Tokyo Institute of Technology, Tokyo, 152-8551, Japan. ksuzuki@chem.titech.ac.jp
authors.forename: Keisuke
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002392:Catechin / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry; D018942:Macrolides / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D001688:Biological Products; D006027:Glycosides; D018942:Macrolides; D013729:Terpenes; D002392:Catechin