title: Cutaneous adverse reactions in in-patients in a tertiary care hospital.
abstract: Cutaneous reactions were monitored by spontaneous adverse reaction monitoring system among inpatients in Nehru Hospital, over a period of 3 1/2 years. A total of 379 adverse drug reactions were reported during this period, of which 144 (40%) were cutaneous reactions. Maculopapular rashes (50% of cutaneous reactions), and urticaria (21.5%) were the most common eruption. Stevens-Johnson syndrome (13.9%) and toxic epidermal necrolysis (TEN 4.9%) were the serious cutaneous reactions. There were 4 fatal cutaneous reactions (all due to TEN). Antimicrobials (caused 56.9% reactions), radiocontrast dyes (14.6% reactions) and antiepileptics (15.3% reactions) were the most prominent drugs responsible for these eruptions.
authors.affiliation: Department of Pharmacology, PGIMER, Chandigarh-160 012, India.
authors.forename: R
authors.initials: R
authors.lastname: Jhaj
authors.forename: R
authors.initials: R
authors.lastname: Uppal
authors.forename: S
authors.initials: S
authors.lastname: Malhotra
authors.forename: V K
authors.initials: VK
authors.lastname: Bhargava