title: Abdominal visceral fat thickness measured by ultrasonography predicts the presence and severity of coronary artery disease.
abstract: Abdominal visceral fat plays a critical role in the pathogenesis of metabolic syndrome, which is a risk factor for coronary artery disease (CAD). Ultrasonography (US) distinctively quantifies visceral fat and subcutaneous fat. We measured the maximum preperitoneal visceral fat thickness (Vmax) and the minimum subcutaneous fat thickness (Smin) by US in 185 patients who underwent coronary angiography. Although the 144 patients with CAD had larger Vmax (8.8 ± 3.6 vs. 6.4 ± 2.8 mm; p < 0.001) than those without, there was no difference in Smin. Vmax of 6.9 mm or higher was an independent predictor of CAD (odds ratio, 3.710, p = 0.008) by multiple logistic regression analysis. Vmax significantly correlated with the number of diseased vessels. Assessment of abdominal visceral fat by US gives us incremental information beyond conventional risk factors for predicting CAD in routine clinical practice.
authors.affiliation: Department of Medicine and Geriatrics, Kochi Medical School, Kochi University, Oko-cho, Nankoku-shi, Kochi, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Hamagawa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Matsumura
authors.forename: Toru
authors.initials: T
authors.lastname: Kubo
authors.forename: Kayo
authors.initials: K
authors.lastname: Hayato
authors.forename: Makoto
authors.initials: M
authors.lastname: Okawa
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Tanioka
authors.forename: Naohito
authors.initials: N
authors.lastname: Yamasaki
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kitaoka
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Yabe
authors.forename: Masanori
authors.initials: M
authors.lastname: Nishinaga
authors.forename: Yoshinori L
authors.initials: YL
authors.lastname: Doi
mesh_terms: D000368:Aged; D015992:Body Mass Index; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000000981:diagnostic imaging*; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012372:ROC Curve; D012307:Risk Factors; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D014463:Ultrasonography