Undifferentiated uterine sarcoma presenting as a pathologic humerus fracture.
BACKGROUND
Undifferentiated uterine sarcomas are rare malignancies often presenting at advanced stage.


METHODS
A female in her ninth decade presented to our MEDCEN emergency department complaining of onset of severe right arm pain while performing activities of daily living. A pathologic humeral fracture was diagnosed and subsequent orthopedic evaluation resulted in a biopsy and placement of her arm in a cooptation splint and sling. An abdominal exam revealed a 10-cm mass in the right lower quadrant that was thought to originate from the uterus. Computed tomography imaging was concerning for a primary endometrial process and she was referred to gynecologic oncology. Her humeral biopsy was consistent with a poorly differentiated metastatic sarcoma. An endometrial biopsy was consistent with undifferentiated uterine sarcoma, the origin of her humeral lesion.


CONCLUSIONS
Humeral metastasis is an uncommon presentation for undifferentiated endometrial sarcomas.
Gonzalez
Michelle N
MN
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA.
DiFurio
Megan J
MJ
Sundborg
Michael J
MJ
Leath
Charles A
CA
D000368:Aged; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005598:Fractures, Spontaneous / Q000473:pathology*; D006801:Humans; D006810:Humeral Fractures / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*