Hyalinizing spindle cell tumor with giant rosettes.
Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences are common, and late metastases have been recorded. A closely related tumor, the so-called hyalinizing spindle cell tumor with giant collagen rosettes (HSCTGR), has also been described, with both the neoplasms having a similar cytogenetic abnormality and clinical behavior. Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas. Two cases of HSCTGR occurring in the lower limb are described in this report.
Ramaswamy
Anikode S
AS
Department of Pathology, People's Education Society Institute of Medical Sciences and Research, Kuppam, India.
Chatura
K Ramakantha
KR
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D009418:S100 Proteins / Q000032:analysis; D012509:Sarcoma / Q000473:pathology*
D009418:S100 Proteins