Race and gender are not independent risk factors of allograft loss after kidney transplantation.
BACKGROUND
Little is known about the impact of gender on kidney allograft survival in black recipients.


METHODS
A total of 805 kidney transplant recipients were reviewed retrospectively.


RESULTS
All blacks compared with all whites had significantly reduced graft survival at 1, 2, and 3 years (89%, 84%, 82% vs 93%, 89%, 87%, respectively, log-rank P = .03). After stratification by race and gender, black females showed the worst graft survival. When black females were excluded, allograft survival between black males and all whites were similar. Black females carried more risk factors for graft loss. Compared with all others, the unadjusted hazard ratio of graft loss for black females was 1.67 (P < .01; 95% confidence interval, 1.15-2.43), but the adjusted hazard ratio was 1.47 (P = .07, 95% confidence interval, .98-2.23).


CONCLUSIONS
Race and gender in a multivariate analysis are not statistically significant independent risk factors for poor allograft outcomes.
McGee
Jennifer
J
Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112-2669, USA. jmcgee@tulane.edu
Magnus
Jeanette H
JH
Zhang
Rubin
R
Florman
Sander S
SS
Hamm
L Lee
LL
Islam
Tareq M
TM
Sullivan
Karen
K
Mruthinti
Navyata
N
Slakey
Douglas P
DP
D044383:Black People / Q000706:statistics & numerical data*; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology / Q000208:ethnology*; D006801:Humans; D016030:Kidney Transplantation / Q000208:ethnology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D044465:White People / Q000706:statistics & numerical data*