Ultrasound propagation velocity and broadband attenuation can help evaluate the healing process of an experimental fracture.
Ultrasonometry seems to have a future for the evaluation of fracture healing. Ultrasound propagation velocity (USPV) significantly decreases at the same time that bone diameter decreases as healing takes place, thus approaching normal values. In this investigation, both USPV and broadband ultrasound attenuation (BUA) were measured using a model of a transverse mid-diaphyseal osteotomy of sheep tibiae. Twenty-one sheep were operated and divided into three groups of seven, according to the follow-up period of 30, 60, and 90 days, respectively. The progress of healing of the osteotomy was checked with monthly conventional radiographs. The animals were killed at the end of the period of observation of each group, both operated-upon and intact tibiae being resected and submitted to the measurement of underwater transverse and direct contact transverse and longitudinal USPV and BUA at the osteotomy site. The intact left tibia of the 21 animals was used for control, being examined on a symmetrical diaphyseal segment. USPV increased while BUA decreased with the progression of healing, with significant differences between the operated and untouched tibiae and between the periods of observation, for most of the comparisons. There was a strong negative correlation between USPV and BUA. Both USPV and BUA directly reflect and can help predict the healing of fractures, but USPV alone can be used as a fundamental parameter. Ultrasonometry may be of use in clinical application to humans provided adequate adaptations can be developed.
Barbieri
Giuliano
G
Department of Biomechanics, Medicine and Rehabilitation of the Locomotor Apparatus, Ribeirão Preto School of Medicine, São Paulo University, São Paulo, Brazil. chbarbie@fmrp.usp.br
Barbieri
Cláudio Henrique
CH
Mazzer
Nilton
N
Pelá
Carlos Alberto
CA
D000818:Animals; D001696:Biomechanical Phenomena; D018483:Diaphyses / Q000000981:diagnostic imaging / Q000293:injuries / Q000503:physiopathology; D004195:Disease Models, Animal; D017102:Fracture Healing / Q000502:physiology*; D016014:Linear Models; D033401:Microscopy, Acoustic / Q000379:methods*; D008954:Models, Biological; D010027:Osteotomy; D012756:Sheep; D013978:Tibial Fractures / Q000000981:diagnostic imaging* / Q000503:physiopathology*