title: [Effects of compound Centella asiatica enema on kidneys coefficient, electrolytes and blood in chronic renal failure rats].
abstract: OBJECTIVE
  To study the pharmacological effects of compound Centella asiatica enema on chronic renal failure (CRF) rats.
  
  
  METHODS
  Rats were divided into control group, CRF model group, Niaoduqing positive control group, compound Centella asiatica enema high, middle and low three groups kidney coefficient, electrolyte levels, hematocrit (HCT), red blood cell counts (RBC), hemoglobin (HGB) content were observed after 30 days's treatment.
  
  
  RESULTS
  Compared with the model group, the level of the electrolyte, HCT, RBC, HGB of rats in compound Centella asiatica enema high-doses group and the Niaoduqing group were significantly improved.
  
  
  CONCLUSIONS
  High-doses of compound Centella asiatica enema has significant therapeutic effect on CRF rats.
authors.affiliation: Southern Medical University Southern Hospital, Guangzhou 510515, China. leilei-p@126.com
authors.forename: Lei-lei
authors.initials: LL
authors.lastname: Pang
authors.forename: Lian-bing
authors.initials: LB
authors.lastname: Hou
authors.forename: Quang-xi
authors.initials: QX
authors.lastname: Mei
authors.forename: Xiang-lian
authors.initials: XL
authors.lastname: Kong
authors.forename: Ying
authors.initials: Y
authors.lastname: Hu
authors.forename: Yu-qiao
authors.initials: YQ
authors.lastname: Gao
authors.forename: Hui
authors.initials: H
authors.lastname: Lin
authors.forename: Zhao-hui
authors.initials: ZH
authors.lastname: Liu
authors.forename: Cong-yan
authors.initials: CY
authors.lastname: Zeng
authors.forename: Yong-yin
authors.initials: YY
authors.lastname: Lian
authors.forename: Zu-rui
authors.initials: ZR
authors.lastname: Zhang
mesh_terms: D000225:Adenine / Q000008:administration & dosage; D000818:Animals; D004195:Disease Models, Animal; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004573:Electrolytes / Q000097:blood*; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009929:Organ Size; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D004573:Electrolytes; D006454:Hemoglobins; D000225:Adenine