Functional interconnection of MYC2 and SPA1 in the photomorphogenic seedling development of Arabidopsis.
MYC2 is a basic helix-loop-helix transcription factor that cross talks with light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. Here, we have shown that Arabidopsis (Arabidopsis thaliana) MYC2 directly binds to the G-box present in the SUPPRESSOR OF PHYTOCHROME A1 (SPA1) promoter and that it controls the expression of SPA1 in a COP1-dependent manner. Analyses of atmyc2 spa1 double mutants suggest that whereas MYC2 and SPA1 act redundantly to suppress photomorphogenic growth in the dark, they function synergistically for the suppression of photomorphogenic growth in the light. Our studies have also revealed that MYC2-mediated ABA and JA responses are further modulated by SPA1. Taken together, this study demonstrates the molecular and physiological interrelations of MYC2 and SPA1 in light, ABA, and JA signaling pathways.
Gangappa
Sreeramaiah N
SN
National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, India.
Prasad
V Babu Rajendra
VB
Chattopadhyay
Sudip
S
D000040:Abscisic Acid / Q000378:metabolism; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / Q000235:genetics / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D003517:Cyclopentanes / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D018525:Germination; D008027:Light; D054883:Oxylipins / Q000378:metabolism; D018517:Plant Roots / Q000254:growth & development; D011401:Promoter Regions, Genetic; D018749:RNA, Plant / Q000235:genetics; D036226:Seedlings / Q000254:growth & development*; D015398:Signal Transduction
D029681:Arabidopsis Proteins; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D018797:Cell Cycle Proteins; D003517:Cyclopentanes; C473611:MYC2 protein, Arabidopsis; D054883:Oxylipins; D018749:RNA, Plant; C118571:SPA1 protein, Arabidopsis; C011006:jasmonic acid; D000040:Abscisic Acid