Backbone assignment and dynamics of human α-synuclein in viscous 2 M glucose solution.
We present (1)H(N), (15)N, (13)C(α), (13)C(β) and (13)C' assignments and (15)N transverse relaxation rates (R(2)) of a Parkinson's disease-related intrinsically disordered protein, α-synuclein, in the presence of 2 M (360 g/l) glucose solution.
Wu
Kuen-Phon
KP
Department of Chemistry and Chemical Biology, BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, NJ 08854, USA.
Baum
Jean
J
D005947:Glucose / Q000737:chemistry*; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D017433:Protein Structure, Secondary; D012996:Solutions; D014783:Viscosity; D051844:alpha-Synuclein / Q000737:chemistry*
C497604:SNCA protein, human; D012996:Solutions; D051844:alpha-Synuclein; D005947:Glucose