title: A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata.
abstract: Three new taxanes, 2 α,9 α,10 β-triacetoxy-13 α-( β-D-glucopyranosyloxy)taxa-4(20),11-dien-5 α-ol, 5 α,10 β,13 α-triacetoxytax-11-ene-2 α,7 β,9 α,20-tetraol, and 5 α,10 β,13 β-triacetoxy-2 α,7 β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one, were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.
authors.affiliation: Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Hebei, P. R. China.
authors.forename: Zhi-Yu
authors.initials: ZY
authors.lastname: Ni
authors.forename: Mei
authors.initials: M
authors.lastname: Dong
authors.forename: Bin
authors.initials: B
authors.lastname: Cong
authors.forename: Françoise
authors.initials: F
authors.lastname: Sauriol
authors.forename: Man-Li
authors.initials: ML
authors.lastname: Zhang
authors.forename: Yu-Fang
authors.initials: YF
authors.lastname: Wang
authors.forename: Chang-Hong
authors.initials: CH
authors.lastname: Huo
authors.forename: Qing-Wen
authors.initials: QW
authors.lastname: Shi
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Kiyota
mesh_terms: D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves; D043823:Taxoids / Q000737:chemistry / Q000302:isolation & purification*; D020946:Taxus / Q000737:chemistry*
chemical_list: C561248:2alpha,9alpha,10beta-triacetoxy-13alpha(beta-D-glucopyranosyloxy)taxa-4(20),11-dien-5alpha-ol; C561246:5alpha,10beta,13alpha-triacetoxytax-11-ene-2alpha,7beta,9alpha,20-tetraol; C561247:5alpha,10beta,13beta-triacetoxy-2 alpha,7beta-dihydroxy-2(3-20) abeotaxa-4(20),11-dien-9-one; D005960:Glucosides; D010936:Plant Extracts; D043823:Taxoids