title: Manifestations of systemic diseases on thoracic imaging.
abstract: A familiarity with the numerous findings in commonly encountered systemic diseases is necessary for the radiologist interpreting any chest study. These systemic diseases include collagen vascular diseases, vasculitides, granulomatous diseases, neoplasms, hematologic and metabolic abnormalities, neurocutaneous syndromes, deposition disease, and miscellaneous conditions such as cystic fibrosis and Goodpasture's syndrome. Although the imaging findings of these and other recognized systemic diseases are often nonspecific and varied, an understanding of their typical manifestations allows the radiologist to play a significant role in suggesting a particular diagnosis and impacting patient care.
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02115, USA.
authors.forename: James
authors.initials: J
authors.lastname: Kang
authors.forename: Diana
authors.initials: D
authors.lastname: Litmanovich
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Bankier
authors.forename: Phillip M
authors.initials: PM
authors.lastname: Boiselle
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Eisenberg
mesh_terms: D000686:Amyloidosis / Q000150:complications; D000755:Anemia, Sickle Cell / Q000150:complications; D001172:Arthritis, Rheumatoid / Q000150:complications*; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000000981:diagnostic imaging; D003550:Cystic Fibrosis / Q000150:complications; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000209:etiology; D008175:Lung Neoplasms / Q000556:secondary; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D009101:Multiple Myeloma / Q000150:complications; D055613:Multiple Pulmonary Nodules / Q000000981:diagnostic imaging / Q000209:etiology; D017253:Neurofibromatoses / Q000150:complications; D012218:Rheumatoid Nodule / Q000000981:diagnostic imaging; D017565:Sarcoidosis, Pulmonary / Q000000981:diagnostic imaging; D012595:Scleroderma, Systemic / Q000150:complications; D012859:Sjogren's Syndrome / Q000150:complications; D013167:Spondylitis, Ankylosing / Q000175:diagnosis; D013896:Thoracic Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000150:complications