title: Comparison of pharyngeal stenosis between hypopharyngeal patients undergoing primary versus salvage laryngopharyngectomy.
abstract: OBJECTIVE
  To survey the risk factors of pharyngeal stenosis after laryngopharyngectomy in patients with advanced hypopharyngeal cancers.
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  Tertiary medical center.
  
  
  METHODS
  Pharyngeal stenosis rates and risk factors were compared between two groups of laryngopharyngectomy patients: a group that underwent concurrent chemoradiation therapy followed by surgical salvage, and a surgery initiated group with adjuvant chemoradiation.
  
  
  RESULTS
  Of 160 patients, 25 developed pharyngeal stenosis, which was diagnosed by barium esophagography with a pooling of barium contrast above the neopharyngeal inlet. These patients required nasogastric tube feeding or gastrostomy feeding because an oral liquid diet could not meet their nutritional needs. Primary closure and old age were risk factors for pharyngeal stenosis. Pharyngeal stenosis did not affect survival in patients with advanced hypopharyngeal cancer who underwent laryngopharyngectomy.
  
  
  CONCLUSIONS
  Primary closure reconstruction is discouraged in patients over the age of 65 years.
authors.affiliation: Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan.
authors.forename: Yung-An
authors.initials: YA
authors.lastname: Tsou
authors.forename: Meng-Hung
authors.initials: MH
authors.lastname: Lin
authors.forename: Chun-Hung
authors.initials: CH
authors.lastname: Hua
authors.forename: Hsien-Chang
authors.initials: HC
authors.lastname: Tseng
authors.forename: Da-Tian
authors.initials: DT
authors.lastname: Bau
authors.forename: Ming-Hsui
authors.initials: MH
authors.lastname: Tsai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D003251:Constriction, Pathologic / Q000209:etiology; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010611:Pharyngectomy / Q000009:adverse effects*; D010614:Pharynx / Q000473:pathology*; D012307:Risk Factors; D016879:Salvage Therapy; D013524:Surgical Flaps / Q000009:adverse effects; D015996:Survival Rate