title: Granada virus: a natural phlebovirus reassortant of the sandfly fever Naples serocomplex with low seroprevalence in humans.
abstract: A new member of the phlebovirus genus, tentatively named Granada virus, was detected in sandflies collected in Spain. By showing the presence of specific neutralizing antibodies in human serum collected in Granada, we show that Granada virus infects humans. The analysis of the complete genome of Granada virus revealed that this agent is likely to be a natural reassortant of the recently described Massilia virus (donor of the long and short segments) with a yet unidentified phlebovirus (donor of the medium segment).
authors.affiliation: Department of Virology, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain. ximecf1@hotmail.com
authors.forename: Ximena
authors.initials: X
authors.lastname: Collao
authors.forename: Gustavo
authors.initials: G
authors.lastname: Palacios
authors.forename: Fernando
authors.initials: F
authors.lastname: de Ory
authors.forename: Sara
authors.initials: S
authors.lastname: Sanbonmatsu
authors.forename: Mercedes
authors.initials: M
authors.lastname: Pérez-Ruiz
authors.forename: José María
authors.initials: JM
authors.lastname: Navarro
authors.forename: Ricardo
authors.initials: R
authors.lastname: Molina
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Hutchison
authors.forename: W Ian
authors.initials: WI
authors.lastname: Lipkin
authors.forename: Antonio
authors.initials: A
authors.lastname: Tenorio
authors.forename: María Paz
authors.initials: MP
authors.lastname: Sánchez-Seco
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001483:Base Sequence; D002522:Chlorocebus aethiops; D005260:Female; D016679:Genome, Viral; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008297:Male; D008969:Molecular Sequence Data; D010217:Phlebotomus Fever / Q000453:epidemiology / Q000821:virology*; D010802:Phylogeny; D011576:Psychodidae / Q000821:virology*; D016865:Reassortant Viruses; D029301:Sandfly fever Naples virus / Q000145:classification* / Q000235:genetics* / Q000276:immunology; D016036:Seroepidemiologic Studies; D014709:Vero Cells
chemical_list: D000914:Antibodies, Viral