title: Comparison of selective arterial spin labeling using 1D and 2D tagging RF pulses.
abstract: Generic arterial spin labeling (ASL) techniques label all brain feeding arteries. In this work, we used two different selective ASL (SASL) methods to show the perfusion of one single artery. A slice selective inversion of an area including the desired vessel was compared to a multidimensional RF pulse with Gaussian profile to label only the artery of interest. Perfusion images with a resolution of 2 x 2 x 5 mm(3) are shown that were acquired after tagging only the internal carotid artery of healthy volunteers. In addition, both techniques were applied to a patient with an extra-intracranial bypass to illustrate its perfusion territory. These perfusion images are consistent with a standard angiography. SASL imaging with a resolution of 2 x 2 x 5 mm(3) is possible in a total scan time of 5 min. The presented MR techniques may in part replace the assessment of revascularization success by conventional angiography.
authors.affiliation: Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Germany. Simon.Konstandin@MedMa.uni-heidelberg.de
authors.forename: Simon
authors.initials: S
authors.lastname: Konstandin
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Heiler
authors.forename: Johann
authors.initials: J
authors.lastname: Scharf
authors.forename: Lothar R
authors.initials: LR
authors.lastname: Schad
mesh_terms: D015901:Angiography, Digital Subtraction; D020771:Anterior Cerebral Artery; D001921:Brain / Q000098:blood supply*; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000503:physiopathology / Q000601:surgery; D002533:Cerebral Angiography / Q000379:methods*; D002548:Cerebral Revascularization; D004292:Dominance, Cerebral / Q000502:physiology; D005583:Fourier Analysis; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D020768:Middle Cerebral Artery; D016011:Normal Distribution; D019047:Phantoms, Imaging; D012039:Regional Blood Flow / Q000502:physiology; D012984:Software; D013113:Spin Labels; D051598:Whole Body Imaging
chemical_list: D013113:Spin Labels