[Study of C-reactive protein expression in type 2 diabetes mellitus complicated with vascular lesions and its clinical significance].
OBJECTIVE
To investigate the effect of C-reactive protein (CRP) expression in type 2 diabetes mellitus (T2DM) complicated with vascular lesions and its clinical significance.


METHODS
90 cases of T2DM patients were divided into vascular disease group (observation group, 45 cases) and non-vascular lesion group (control group, 45 cases), the CRP, FPG, HbAlc, TC, LDL-C and HDL-C levels of the two groups were measured, the blood pressure and BMI were recorded.


RESULTS
(1) The serum CRP concentration and blood pressure levels of the observation group were higher than the control group, compared with the difference was significant (P<0.05), and the FPG levels and HbAlc values of the two groups were no significantly difference (P>0.05). (2) The serum TG, Fins level and BMI of the observation group were higher than the control group, compared with the difference was significant (P<0.05), and the HDL-C and LDL-C levels of the two groups were no significantly difference.


CONCLUSIONS
The serum CRP combine with the blood pressure, blood lipids, body weight and insulin indicators has important clinical significance for early diagnosis, prevention, treatment and prognosis of T2DM complication with vascular lesions.
Ran
Rui-zhen
RZ
Yulin Health Center, Wuhou District, Chengdu, China.
Tu
Yan-yang
YY
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000235:genetics / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D015870:Gene Expression; D006801:Humans; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D014652:Vascular Diseases / Q000097:blood* / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics
D014280:Triglycerides; D002097:C-Reactive Protein; D002784:Cholesterol