Miniaturisation of a capillary electrophoresis microchip for the sensing of endocrine disruptors.
Although capillary electrophoresis amperometric detector (CE-AD) involving double-T microchannel configuration is a powerful analytical tool in terms of sensitivity and selectivity, its long microchannel configuration hinders further miniaturisation. Therefore a twisted CE microchannel configuration was used in the present study to fabricate CE-AD devices for detection of endocrine disruptors. The analyte separation time varied slightly for the twisted microchannel structure, whereas the detector sensitivities were similar for the two configurations. The conventional indium tin oxide amperometric detector in the device with twisted microchannel configuration was later modified with Prussian blue to enhance the sensitivity of detection.
Ha
K
K
Myongji University, Department of Nano Science and Engineering, Gyeonggi, Korea.
Joo
G-S
GS
Jha
S K
SK
Yeon
I-J
IJ
Kim
Y-S
YS
D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D046209:Electrophoresis, Microchip / Q000295:instrumentation*; D052244:Endocrine Disruptors / Q000032:analysis*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008904:Miniaturization
D052244:Endocrine Disruptors