Influence of protein intake and muscle mass on survival in chronic dialysis patients.
BACKGROUND
Some studies suggest that high body mass index (BMI) confers survival advantage in dialysis patients, but BMI does not differentiate muscle from fat mass, and the survival advantage conferred by its increase seems to be limited to patients with high muscle mass. Thus, discriminating body components when evaluating nutritional status and survival is highly important. This study evaluated the influence of nutritional parameters on survival in patients on chronic dialysis.


METHODS
Anthropometry, bioimpedance, biochemistry, and dietary recall were used to investigate the influence of nutritional parameters on survival in 79 prevalent patients on chronic dialysis.


RESULTS
Protein intake <1.2 g/kg/day and creatinine <9.7 mg/dL were independent predictors of mortality in all patients. Regarding dialysis method, protein intake <1.2 g/kg/day was predictive of mortality among hemodialysis patients, and percent standard mid-arm muscle circumference <80% was identified as a risk factor among peritoneal dialysis patients.


CONCLUSIONS
Higher muscle mass, possibly favored by a higher protein intake, conferred survival advantage in dialysis patients.
Antunes
Aline Araujo
AA
Department of Clinical Medicine, Botucatu School of Medicine, São Paulo State University, UNESP, Botucatu, São Paulo, Brazil.
Delatim Vannini
Francieli
F
de Arruda Silveira
Liciana Vaz
LV
Martin
Luis Cuadrado
LC
Barretti
Pasqual
P
Caramori
Jacqueline Costa Teixeira
JC
D000328:Adult; D000368:Aged; D001823:Body Composition; D001938:Brazil / Q000453:epidemiology; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009132:Muscles; D009752:Nutritional Status; D011446:Prospective Studies; D006435:Renal Dialysis
D004044:Dietary Proteins