title: Polymer translocation into a fluidic channel through a nanopore.
abstract: Using two-dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter R through a nanopore under a driving force F . Due to the crowding effect induced by the partially translocated monomers, the translocation dynamics is significantly altered in comparison to an unconfined environment, namely, we observe a nonuniversal dependence of the translocation time τ on the chain length N . τ initially decreases rapidly and then saturates with increasing R , and a dependence of the scaling exponent α of τ with N on the channel width R is observed. The otherwise inverse linear scaling of τ with F breaks down and we observe a minimum of α as a function of F . These behaviors are interpreted in terms of the waiting time of an individual segment passing through the pore during translocation.
authors.affiliation: Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui Province, People's Republic of China. kluo@ustc.edu.cn
authors.forename: Kaifu
authors.initials: K
authors.lastname: Luo
authors.forename: Ralf
authors.initials: R
authors.lastname: Metzler
mesh_terms: D001704:Biopolymers / Q000737:chemistry*; D002462:Cell Membrane / Q000737:chemistry* / Q000502:physiology*; D002463:Cell Membrane Permeability / Q000502:physiology*; D003198:Computer Simulation; D044085:Microfluidics / Q000379:methods*; D008954:Models, Biological; D008956:Models, Chemical; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D016062:Porosity
chemical_list: D001704:Biopolymers