Synthesis of (±)-chamobtusin A by a presumed biomimetic aza-cyclization.
A total synthesis of (±)-chamobtusin A has been accomplished on the basis of our presumed biosynthetic pathway: the imine formation of keto aldehyde followed by intramolecular aza-Michael addition.
Kuzuya
Kazuma
K
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Mori
Naoki
N
Watanabe
Hidenori
H
D001372:Aza Compounds / Q000737:chemistry*; D040761:Biomimetic Materials / Q000737:chemistry*; D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis*; D015394:Molecular Structure
D001372:Aza Compounds; D004224:Diterpenes; C525487:chamobtusin A