Pd-catalyzed dearboxylative Heck coupling with dioxygen as the terminal oxidant.
Pd-catalyzed decarboxylative Heck coupling of aromatic carboxylic acids with various olefins is developed using O(2) as the terminal oxidant. Enhancement of O(2) pressure leads to improving reaction turnover in this transformation and allows significantly reducing catalyst loading for efficient conversion of electron-rich benzoic acids. A Pd catalyst supported by a carbene ligand enables using electron-deficient benzoic acids as coupling partners.
Fu
Zhengjiang
Z
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, PR China.
Huang
Shijun
S
Su
Weiping
W
Hong
Maochun
M