A case of acetaminophen (paracetamol) causing renal failure without liver damage in a child and review of literature.
Acetaminophen (paracetamol) is a widely used drug and known as a safety antipyretic and analgesic drug in childhood. Acetaminophen-associated liver damage is more recognized than kidney damage. Nephrotoxicity and hepatotoxicity can be seen together after acetaminophen overdose, but renal damage without liver damage is a rarely seen entity in all age groups being reported more rarely in childhood. We present here a 16-year-old girl with renal failure without liver damage because of acetaminophen toxicity and a review of literature for pathophysiological mechanisms, clinical course, treatment, and outcome.
Ozkaya
Ozan
O
Department of Pediatric Nephrology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
Genc
Gurkan
G
Bek
Kenan
K
Sullu
Yurdanur
Y
D000082:Acetaminophen / Q000506:poisoning*; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D051437:Renal Insufficiency / Q000139:chemically induced*
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen