SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks.
SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.


BACKGROUND
http://www.win.tue.nl/∼mwestenb/spotxplore/.
Westenberg
Michel A
MA
Department of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands. m.a.westenberg@tue.nl
Roerdink
Jos B T M
JB
Kuipers
Oscar P
OP
van Hijum
Sacha A F T
SA
D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D053263:Gene Regulatory Networks / Q000235:genetics*; D012984:Software; D014584:User-Computer Interface