title: Numerical simulation of LDL mass transfer in a common carotid artery under pulsatile flows.
abstract: Symmetrical 30-60% stenosis in carotid artery with a semi-permeable wall under steady/unsteady flows for Newtonian/non-Newtonian fluids is investigated numerically. The results show that the unsteadiness of blood flow, blood pressure rise and LDL component size increase the luminal concentration, LC, of the surface. The maximum LC occurring immediately after the separation point and the non-Newtonian fluid predicts higher LDL accumulation. LC decreased as the recirculation length is increased and reaches maximum at 40% stenosis. This process is used to estimate the time-dependent growth of the arterial wall.
authors.affiliation: Department of Mechanical Engineering, Isfahan University of Technology, Isfahan 8415683111, Iran.
authors.forename: S
authors.initials: S
authors.lastname: Fazli
authors.forename: E
authors.initials: E
authors.lastname: Shirani
authors.forename: M R
authors.initials: MR
authors.lastname: Sadeghi
mesh_terms: D001696:Biomechanical Phenomena; D017536:Carotid Artery, Common / Q000473:pathology / Q000502:physiology* / Q000503:physiopathology; D016893:Carotid Stenosis / Q000097:blood / Q000473:pathology / Q000503:physiopathology; D003198:Computer Simulation; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood* / Q000737:chemistry; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology*
chemical_list: D008077:Lipoproteins, LDL