Long noncoding RNAs add another layer to pre-mRNA splicing regulation.
In this issue of Molecular Cell, Tripathi and coworkers (Tripathi et al., 2010) decode some of the functions of a long noncoding RNA MALAT1. They provide evidence that MALAT1 regulates alternative splicing by controlling the activity of the SR protein family of splicing factors.
Ankö
Minna-Liisa
ML
Max Planck Institute of Cell Biology and Genetics, Dresden, Germany.
Neugebauer
Karla M
KM