title: Prevalence of metabolic syndrome, insulin resistance, impaired fasting blood glucose, and dyslipidemia in Uygur and Kazak populations.
abstract: This study was designed to evaluate the prevalence of the metabolic syndrome (MetS), impaired fasting blood glucose (IFG), insulin resistance (IR), hypertriglyceridemia (HTG), and low high-density lipoprotein cholesterol (HDL-C) in adult Uygur and Kazak populations. Questionnaires, blood pressure, anthropometric measurement, and fasting glucose were evaluated. The age-adjusted prevalence of MetS and IFG was 3.43- and 1.47-fold higher, respectively, in Uygurs compared with Kazaks. The prevalence of IR and HTG was 1.33- and 2.22-fold higher, respectively, in Uygurs compared with Kazaks. In addition, the prevalence of low HDL-C was 4.05-fold higher in Uygurs compared with Kazaks. These data depicted greater risk for cardiometabolic syndrome in Uygurs compared with Kazaks. In addition, all prevalence with the exception of low HDL-C was greater in men compared with women in both ethnic groups. For body mass index (BMI)<24, 24 to 28, and ≥28 kg/m2, the prevalence of MetS, HTG, and low HDL-C was higher in Uygurs than Kazaks at the same BMI level. For individuals with a BMI between 24 and 28, the prevalence of IR but not IFG was significantly greater in Uygurs than Kazaks. At BMI≥28, neither IFG nor IR was overtly different between the two ethnic groups.
authors.affiliation: Xinjiang Medical University, the Department of Endocrinology, First Affiliate Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
authors.forename: Lifeng
authors.initials: L
authors.lastname: Wang
authors.forename: Yicun
authors.initials: Y
authors.lastname: Tao
authors.forename: Zijing
authors.initials: Z
authors.lastname: Xie
authors.forename: Xinjian
authors.initials: X
authors.lastname: Ran
authors.forename: Minfang
authors.initials: M
authors.lastname: Zhang
authors.forename: Ye
authors.initials: Y
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Luo
authors.forename: Mengying
authors.initials: M
authors.lastname: Hu
authors.forename: Wenning
authors.initials: W
authors.lastname: Gen
authors.forename: Hamulati
authors.initials: H
authors.lastname: Wufuer
authors.forename: Linlin
authors.initials: L
authors.lastname: Li
authors.forename: Jun
authors.initials: J
authors.lastname: Ren
authors.forename: Xinming
authors.initials: X
authors.lastname: Mao
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose; D002681:China; D008076:Cholesterol, HDL; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000453:epidemiology* / Q000208:ethnology; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology* / Q000208:ethnology; D015228:Hypertriglyceridemia / Q000453:epidemiology / Q000208:ethnology; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000208:ethnology; D008875:Middle Aged; D015995:Prevalence; D011795:Surveys and Questionnaires
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL