The adaptation of Rice yellow mottle virus to the eIF(iso)4G-mediated rice resistance.
The rymv1-3 allele of the eIF(iso)4G-mediated resistance to Rice yellow mottle virus (RYMV) is found in a few Oryza glaberrima cultivars. The same resistance-breaking (RB) mutations emerged in the central domain of the VPg after inoculation of isolates of different strains. The RB mutations were fixed, often sequentially, at codons 41 and 52 which paralleled an increase in virus accumulation. RB mutations also emerged after inoculation of an avirulent infectious clone, indicating that they were generated de novo in resistant plants. Only virus isolates with a threonine at codon 49 of the VPg broke rymv1-3 resistance, those with a glutamic acid did not. A small subset of these isolates overcame rymv1-2 resistance, but following a specific pathway. Comparison with the RB process of rymv1-2, a resistance allele found in a few Oryza sativa cultivars, showed similarities in the mode of adaptation but revealed converse virulence specificity of the isolates.
Traoré
Oumar
O
Institut de l'Environnement et de Recherches Agricoles, Ouagadougou, Burkina Faso.
Pinel-Galzi
Agnès
A
Issaka
Souley
S
Poulicard
Nils
N
Aribi
Jamel
J
Aké
Séverin
S
Ghesquière
Alain
A
Séré
Yacouba
Y
Konaté
Gnissa
G
Hébrard
Eugénie
E
Fargette
Denis
D
D000220:Adaptation, Biological; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution / Q000235:genetics; D005075:Biological Evolution; D016000:Cluster Analysis; D003062:Codon; D039603:Eukaryotic Initiation Factor-4G / Q000378:metabolism*; D008969:Molecular Sequence Data; D020125:Mutation, Missense; D012275:Oryza / Q000276:immunology* / Q000821:virology*; D010802:Phylogeny; D010935:Plant Diseases / Q000821:virology; D010942:Plant Viruses / Q000254:growth & development* / Q000276:immunology* / Q000472:pathogenicity; D012328:RNA Viruses / Q000254:growth & development* / Q000276:immunology* / Q000472:pathogenicity; D017385:Sequence Homology; D014764:Viral Proteins / Q000235:genetics; D014774:Virulence
D003062:Codon; D039603:Eukaryotic Initiation Factor-4G; D014764:Viral Proteins