Screening of natural antioxidants from traditional Chinese medicinal plants associated with treatment of rheumatic disease.
In order to find new sources of natural antioxidants, the antioxidant capacities of 50 medicinal plants associated with treatment of rheumatic diseases were systemically evaluated using the ferric-reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, and their total phenolic contents were measured by the Folin-Ciocalteu method. Their antioxidant activities of some of these plants were analyzed for the first time. The FRAP and TEAC assay results suggested that the antioxidant compounds in these plants possessed free radicals scavenging activity and oxidant reducing power. A positive linear correlation between antioxidant capacities and total phenolic contents implied that phenolic compounds in these plants could be the main components contributing to the observed activities. The results showed that Geranium wilfordii, Loranthus parasiticus, Polygonum aviculare, Pyrrosia sheaeri, Sinomenium acutum and Tripterygium wilfordii possessed the highest antioxidant capacities and total phenolic content among 50 plants tested, and could be rich potential sources of natural antioxidants.
Gan
Ren-You
RY
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou, China. ganry_zsu@yahoo.cn
Kuang
Lei
L
Xu
Xiang-Rong
XR
Zhang
Yuan
Y
Xia
En-Qin
EQ
Song
Feng-Lin
FL
Li
Hua-Bin
HB
D000975:Antioxidants / Q000032:analysis* / Q000302:isolation & purification / Q000627:therapeutic use; D001688:Biological Products / Q000032:analysis; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers / Q000032:analysis; D010084:Oxidation-Reduction; D010636:Phenols / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry*; D012216:Rheumatic Diseases / Q000188:drug therapy*
D000975:Antioxidants; D001688:Biological Products; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D010636:Phenols