title: [Propanolol used in treatment of infantile hemangioma].
abstract: BACKGROUND
  Infantile hemangiomas are benign vascular tumors that affect 8-12 % of infants. Several recent articles describe effect of propanolol in this patient group. We report a case and present a short review of the literature.
  
  
  METHODS
  The article is based on literature retrieved through a non-systematic search in Pubmed, and our own experience in using propanolol for treatment of a patient with infantile hemangioma.
  
  
  RESULTS
  Our patient responded quickly to propanolol, with a clinical response within few days. Literature describes reduced size and changes in the colour of hemangiomas within 24-48 hours. Our experience is in line with that reported in the literature. Propanolol treatment of this patient group has only been documented in observational studies of small groups and no prospective clinical studies have been reported.
  
  
  CONCLUSIONS
  Propanolol seems to be an effective treatment of infantile hemangiomas. Prospective controlled studies are needed to document optimal dosing, need for monitoring, side effects and duration of therapy.
authors.affiliation: Hudavdelingen, St. Olavs hospital, 7006 Trondheim, Norway. kjetil.guldbakke@stolav.no
authors.forename: Kjetil K S
authors.initials: KK
authors.lastname: Guldbakke
authors.forename: Ole-Martin
authors.initials: OM
authors.lastname: Rørdam
authors.forename: Theis
authors.initials: T
authors.lastname: Huldt-Nystrøm
authors.forename: Helle Kathrine
authors.initials: HK
authors.lastname: Hanssen
authors.forename: Finn
authors.initials: F
authors.lastname: Høivik
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000188:drug therapy*; D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol