Fluorescent labeling of human mesenchymal stem cells by thiophene fluorophores conjugated to a lipophilic carrier.
Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.
Duca
Maria
M
LCMBA UMR6001 CNRS Institut de Chimie de Nice, Université de Nice Sophia Antipolis, Parc Valrose, 06100 Nice, France. maria.duca@unice.fr
Dozza
Barbara
B
Lucarelli
Enrico
E
Santi
Spartaco
S
Di Giorgio
Audrey
A
Barbarella
Giovanna
G
D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D013876:Thiophenes / Q000737:chemistry*
D005456:Fluorescent Dyes; D013876:Thiophenes