title: [Clinical significance of detection of IL-2R for non-small cell lung cancer.].
abstract: BACKGROUND
  To explore the clinical significance of SIL-2R of serum and IL-2R expression of cancer tissue in non-small cell lung cancer.
  
  
  METHODS
  SIL-2R levels in the serum and IL-2R expression in cancer tissues were detected in 42 non-small cell lung cancer by ELISA and immunohistochemistry respectively.
  
  
  RESULTS
  Serum SIL-2R level was significantly higher in lung cancer group than that in normal control group ( P < 0. 05) , and significantly higher in stage III, IV disease than that in stage I, II disease ( P < 0. 05) , but it was not associated with histological classification of the cancer ( P > 0. 05) . IL-2R expression was significantly higher in lung cancer tissue than that in normal lung tissue ( P < 0. 05) and was significantly higher in stage III, IV cancer than that in stage I, II cancer ( P < 0. 05) . But it was not related to cancer types ( P > 0. 05) .
  
  
  CONCLUSIONS
  The results suggest that detection of serum SIL-2R and IL-2R expression of the cancer tissue might be useful to predict stages of cancer and monitor the prognosis of patients with lung cancer.
authors.affiliation: Department of Thoracic Surgery , The Affiliated Hospital of Shandong Medical University , Jinan 250012 , P. R. China.
authors.forename: H
authors.initials: H
authors.lastname: Tian
authors.forename: B
authors.initials: B
authors.lastname: Cao
authors.forename: S
authors.initials: S
authors.lastname: Wang