title: The usefulness of toluidine red unheated serum test in the diagnosis of HIV-negative neurosyphilis.
abstract: We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the indication of lumbar puncture in syphilitic patients and a reactive cerebrospinal fluid-TRUST is considered diagnostic to neurosyphilis.
authors.affiliation: Department of Neurology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Jiang
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Chen
authors.forename: Xiaomeng
authors.initials: X
authors.lastname: Ma
authors.forename: Yu
authors.initials: Y
authors.lastname: Yang
authors.forename: Fuhua
authors.initials: F
authors.lastname: Peng
authors.forename: Xueqiang
authors.initials: X
authors.lastname: Hu
mesh_terms: D000372:Agglutination Tests / Q000379:methods; D000907:Antibodies, Bacterial / Q000097:blood* / Q000134:cerebrospinal fluid*; D001391:Azo Compounds; D016009:Chi-Square Distribution; D006801:Humans; D007958:Leukocyte Count; D009494:Neurosyphilis / Q000175:diagnosis* / Q000382:microbiology; D011935:Reagins / Q000097:blood / Q000134:cerebrospinal fluid; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013588:Syphilis Serodiagnosis / Q000379:methods*; D014210:Treponema pallidum / Q000302:isolation & purification*
chemical_list: D000907:Antibodies, Bacterial; D001391:Azo Compounds; D011935:Reagins; C037318:toluidine red