Thyroglobulin gene is associated with premature ovarian failure.
Variants of the thyroglobulin gene were significantly associated with premature ovarian failure in a Korean population. Three single nucleotide polymorphisms and one haplotype were found to be associated with a significant increase in the risk for premature ovarian failure.
Pyun
Jung-A
JA
Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Republic of Korea.
Kang
HyunJun
H
Kim
JiHye
J
Cha
Dong Hyun
DH
Kwack
KyuBum
K
D000328:Adult; D044466:Asian People / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D007037:Hypothyroidism / Q000453:epidemiology* / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D016649:Primary Ovarian Insufficiency / Q000453:epidemiology* / Q000235:genetics*; D012307:Risk Factors; D013954:Thyroglobulin / Q000235:genetics*
D013954:Thyroglobulin