title: Boronic acid porphyrin receptor for ginsenoside sensing.
abstract: Ginsenoside detection was pursued through the design of a porphyrin receptor containing two boronic acid units. This receptor was found to undergo different degrees of fluorescence quenching with five ginsenoside guests and an acylated derivative. The trends in the 1:1 binding constants, as well as ESI-HRMS analysis, support a binding mode in which the ginsenoside sugar units are bound to the boronic acid groups, while the steroid core and porphyrin ring participate in hydrophobic interactions.
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-0165, United States.
authors.forename: Amanda E
authors.initials: AE
authors.lastname: Hargrove
authors.forename: Ryan N
authors.initials: RN
authors.lastname: Reyes
authors.forename: Ian
authors.initials: I
authors.lastname: Riddington
authors.forename: Eric V
authors.initials: EV
authors.lastname: Anslyn
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Sessler
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D036145:Ginsenosides / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*
chemical_list: D001897:Boronic Acids; D036145:Ginsenosides; D011166:Porphyrins