Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
Ghosal
Anima
A
Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, Kenilworth, New Jersey 07033, USA. anima.ghosal@spcorp.com
Lu
Xiaowen
X
Penner
Natalia
N
Gao
Lan
L
Ramanathan
Ragu
R
Chowdhury
Swapan K
SK
Kishnani
Narendra S
NS
Alton
Kevin B
KB