1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties.
Lebsack
Alec D
AD
Johnson & Johnson Pharmaceutical Research and Development LLC, San Diego, CA 92121, USA. alebsack@its.jnj.com
Rech
Jason C
JC
Branstetter
Bryan J
BJ
Hawryluk
Natalie A
NA
Merit
Jeffrey E
JE
Allison
Brett
B
Rynberg
Raymond
R
Buma
Johnathan
J
Rizzolio
Michele
M
Swanson
Nadia
N
Ao
Hong
H
Maher
Michael P
MP
Herrmann
Michelle
M
Freedman
Jamie
J
Scott
Brian P
BP
Luo
Lin
L
Bhattacharya
Anindya
A
Wang
Qi
Q
Chaplan
Sandra R
SR
Wickenden
Alan D
AD
Breitenbucher
J Guy
JG