title: Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome.
authors.affiliation: Synthetic Research Department, ASKA Pharmaceutical Co, Ltd, 5-36-1, Shimosakunobe, Takatsu-ku, Kawasaki 213-8522, Japan. asagarasu-a@aska-pharma.co.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Asagarasu
authors.forename: Teruaki
authors.initials: T
authors.lastname: Matsui
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Satoru
authors.initials: S
authors.lastname: Tamaoki
authors.forename: Yukinao
authors.initials: Y
authors.lastname: Yamauchi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Minato
authors.forename: Michitaka
authors.initials: M
authors.lastname: Sato