XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Carter
Bing Z
BZ
Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Mak
Duncan H
DH
Morris
Stephen J
SJ
Borthakur
Gautam
G
Estey
Elihu
E
Byrd
Anna L
AL
Konopleva
Marina
M
Kantarjian
Hagop
H
Andreeff
Michael
M