Combination of escitalopram and a 5-HT(₁A) receptor antagonist selectively decreases the extracellular levels of dopamine in the nucleus accumbens relative to striatum through 5-HT(₂C) receptor stimulation; suggestive of antipsychotic potential.
Hovelsø
Nanna
N
Department of Neurophysiology, H. Lundbeck A/S, Denmark. nann@lundbeck.com
Sager
Thomas Nicolaj
TN
Mørk
Arne
A