Hsp90 (heat shock protein 90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo.
Tillotson
Bonnie
B
Infinity Pharmaceuticals, Cambridge, Massachusetts 02139, USA. bonnie.tillotson@infi.com
Slocum
Kelly
K
Coco
John
J
Whitebread
Nigel
N
Thomas
Brian
B
West
Kip A
KA
MacDougall
John
J
Ge
Jie
J
Ali
Janid A
JA
Palombella
Vito J
VJ
Normant
Emmanuel
E
Adams
Julian
J
Fritz
Christian C
CC