Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy.
Abanades
Sergio
S
GlaxoSmithKline, Clinical Imaging Centre, Hammersmith Hospital, London, UK.
van der Aart
Jasper
J
Barletta
Julien A R
JA
Marzano
Carmine
C
Searle
Graham E
GE
Salinas
Cristian A
CA
Ahmad
Javaad J
JJ
Reiley
Richard R
RR
Pampols-Maso
Sabina
S
Zamuner
Stefano
S
Cunningham
Vincent J
VJ
Rabiner
Eugenii A
EA
Laruelle
Marc A
MA
Gunn
Roger N
RN