Synthesis of enantiopure trans-N-Boc-3-aminobicyclo[2.2.2]octane-2-carboxylic acids and their bicyclic 1,3-amino alcohol derivatives via the [4+2] cycloaddition of 1,3-cyclohexadiene to a chiral β-nitroacrylate.
Calmes
Monique
M
Institut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS-UM1-UM2, Université Montpellier 2, Bâtiment Chimie (17), 34095 Montpellier cedex 5, France. monique.calmes@univ-montp2.fr
Escale
Françoise
F
Didierjean
Claude
C
Martinez
Jean
J