FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.
Bravard
Amélie
A
INSERM, IFR, Oullins, France.
Lefai
Etienne
E
Meugnier
Emmanuelle
E
Pesenti
Sandra
S
Disse
Emmanuel
E
Vouillarmet
Julien
J
Peretti
Nöel
N
Rabasa-Lhoret
Rémi
R
Laville
Martine
M
Vidal
Hubert
H
Rieusset
Jennifer
J