Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer.
Buck
Elizabeth
E
Translational Research, OSI Pharmaceuticals, Inc., Farmingdale, New York 11735, USA. ebuck@osip.com
Gokhale
Prafulla C
PC
Koujak
Susan
S
Brown
Eric
E
Eyzaguirre
Alexandra
A
Tao
Nianjun
N
Rosenfeld-Franklin
Maryland
M
Lerner
Lorena
L
Chiu
M Isabel
MI
Wild
Robert
R
Epstein
David
D
Pachter
Jonathan A
JA
Miglarese
Mark R
MR