Synthesis, in vitro and in vivo release kinetics, and anti-HIV activity of a sustained-release prodrug (mPEG-AZT) of 3'-azido-3'-deoxythymidine (AZT, Zidovudine).
Li
Wenjun
W
Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, 44 Wenhuaxi Road, Jinan 250012, PR China.
Chang
Yu
Y
Zhan
Peng
P
Zhang
Na
N
Liu
Xinyong
X
Pannecouque
Christophe
C
De Clercq
Erik
E