title: Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.
authors.affiliation: Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA. shuwen_he@merck.com
authors.forename: Shuwen
authors.initials: S
authors.lastname: He
authors.forename: Zhixiong
authors.initials: Z
authors.lastname: Ye
authors.forename: Peter H
authors.initials: PH
authors.lastname: Dobbelaar
authors.forename: Raman K
authors.initials: RK
authors.lastname: Bakshi
authors.forename: Qingmei
authors.initials: Q
authors.lastname: Hong
authors.forename: James P
authors.initials: JP
authors.lastname: Dellureficio
authors.forename: Iyassu K
authors.initials: IK
authors.lastname: Sebhat
authors.forename: Liangqin
authors.initials: L
authors.lastname: Guo
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.forename: Tianying
authors.initials: T
authors.lastname: Jian
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Lai
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Franklin
authors.forename: Mikhail
authors.initials: M
authors.lastname: Reibarkh
authors.forename: Mark A
authors.initials: MA
authors.lastname: Holmes
authors.forename: David H
authors.initials: DH
authors.lastname: Weinberg
authors.forename: Tanya
authors.initials: T
authors.lastname: MacNeil
authors.forename: Rui
authors.initials: R
authors.lastname: Tang
authors.forename: Constantin
authors.initials: C
authors.lastname: Tamvakopoulos
authors.forename: Qianping
authors.initials: Q
authors.lastname: Peng
authors.forename: Randy R
authors.initials: RR
authors.lastname: Miller
authors.forename: Ralph A
authors.initials: RA
authors.lastname: Stearns
authors.forename: Howard Y
authors.initials: HY
authors.lastname: Chen
authors.forename: Airu S
authors.initials: AS
authors.lastname: Chen
authors.forename: Alison M
authors.initials: AM
authors.lastname: Strack
authors.forename: Tung M
authors.initials: TM
authors.lastname: Fong
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Wyvratt
authors.forename: Ravi P
authors.initials: RP
authors.lastname: Nargund