Synthesis of 2',4'-propylene-bridged (carba-ENA) thymidine and its analogues: the engineering of electrostatic and steric effects at the bottom of the minor groove for nuclease and thermodynamic stabilities and elicitation of RNase H.
Liu
Yi
Y
Bioorganic Chemistry Program, Department of Cell and Molecular Biology, Box 581, Biomedical Center, Uppsala University, SE-751 23 Uppsala, Sweden.
Xu
Jianfeng
J
Karimiahmadabadi
Mansoureh
M
Zhou
Chuanzheng
C
Chattopadhyaya
Jyoti
J