Helicobacter pylori VacA reduces the cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-XL, leading to apoptosis in gastric epithelial cells.
Matsumoto
Ayako
A
Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, and Department of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Isomoto
Hajime
H
Nakayama
Masaaki
M
Hisatsune
Junzo
J
Nishi
Yoshito
Y
Nakashima
Yujiro
Y
Matsushima
Kayoko
K
Kurazono
Hisao
H
Nakao
Kazuhiko
K
Hirayama
Toshiya
T
Kohno
Shigeru
S