A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
McDonald
David A
DA
Molecular Genetics and Microbiology Department, Duke University Medical Center, Durham, NC 27710, USA.
Shenkar
Robert
R
Shi
Changbin
C
Stockton
Rebecca A
RA
Akers
Amy L
AL
Kucherlapati
Melanie H
MH
Kucherlapati
Raju
R
Brainer
James
J
Ginsberg
Mark H
MH
Awad
Issam A
IA
Marchuk
Douglas A
DA