[Management of candidemia and invasive candidiasis].
Candida species is the fourth most common cause of bloodstream infection and is the leading cause of invasive fungal infection among hospitalized patients. Acute disseminated candidiasis remains a life-threatening disease that now occurs mainly in intensive care units hospitalized patients. Delay in treatment of Candida bloodstream infections could be minimized by the development of more rapid and sensitive diagnostic techniques for the identification of Candida bloodstream infections. Current guidelines for the management of invasive candidiasis recommend fluconazole or an echinocandin as the primary therapeutic option. The optimal choice of the antifungal agent should depend on local epidemiology, prior antifungal therapy and patient's characteristics.
Service des maladies infectieuses et tropicales, centre d’infectiologie Necker-Pasteur, université Paris Descartes, hôpital Necker Enfants-malades, 149 rue de Sèvres, Paris cedex 15, France.
F
F
Taieb
F
F
Méchaï
A
A
Lefort
F
F
Lanternier
M-E
ME
Bougnoux
O
O
Lortholary
D058387:Candidemia / Q000188:drug therapy* / Q000453:epidemiology; D002177:Candidiasis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D003663:Decision Trees; D006801:Humans