Rates and patterns of microsatellite mutations in common carp (Cyprinus carpio L.).
During genotyping 150 microsatellites in a F1 family of common carp, six mutations were found at five microsatellite loci. The overall mutation rate of common carp microsatellites was 2.53 X 10(-4) per locus per generation. At five loci, mutations increased the length of alleles by at least one repeat unit, suggesting mutations at microsatellite loci in common carp do not follow strict stepwise mutation model. The data on mutation rates and patterns can facilitate population genetics studies, and provide useful parameters for estimating a long-term effective population size of common carp.
The Centre for Applied Aquatic Genomics, Chinese Academy of Fishery Sciences, Beijing 100141, China. zhangy@cafs.ac.cn
Yan
Y
Zhang
Cui-Yun
CY
Lu
Ding-Chen
DC
Cao
Peng
P
Xu
Shu
S
Wang
Heng-De
HD
Li
Zi-Xia
ZX
Zhao
Xiao-Wen
XW
Sun
D000818:Animals; D002347:Carps / Q000235:genetics*; D018895:Microsatellite Repeats; D009154:Mutation