Genome-wide patterns of genetic variation among elite maize inbred lines.
We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.
State Key Lab of Agrobiotechnology, China Agricultural University, Beijing, China.
Jinsheng
J
Lai
Ruiqiang
R
Li
Xun
X
Xu
Weiwei
W
Jin
Mingliang
M
Xu
Hainan
H
Zhao
Zhongkai
Z
Xiang
Weibin
W
Song
Kai
K
Ying
Mei
M
Zhang
Yinping
Y
Jiao
Peixiang
P
Ni
Jianguo
J
Zhang
Dong
D
Li
Xiaosen
X
Guo
Kaixiong
K
Ye
Min
M
Jian
Bo
B
Wang
Huisong
H
Zheng
Huiqing
H
Liang
Xiuqing
X
Zhang
Shoucai
S
Wang
Shaojiang
S
Chen
Jiansheng
J
Li
Yan
Y
Fu
Nathan M
NM
Springer
Huanming
H
Yang
Jian
J
Wang
Jingrui
J
Dai
Patrick S
PS
Schnable
Jun
J
Wang
D032461:Chromosomes, Plant / Q000235:genetics; D018744:DNA, Plant / Q000235:genetics; D017343:Genes, Plant / Q000235:genetics; D014644:Genetic Variation; D055106:Genome-Wide Association Study; D007178:Inbreeding; D020641:Polymorphism, Single Nucleotide; D003313:Zea mays / Q000235:genetics*
D018744:DNA, Plant