A new isoflavanone from Iresine herbstii.
A new isoflavanone 2',2,5-trimethoxy-6,7-methylenedioxyisoflavanone was isolated from the aerial parts of Iresine herbstii, together with isoflavone tlatlancuayin (2',5-dimethoxy-6,7-methylenedioxyisoflavone). The structure was identified using spectroscopic analysis. This is the first description of a methoxy group occurrence at position 2 of the isoflavanone skeleton. Both isolated compounds were tested for α-glucosidase inhibitory activity, but showed only a low effect compared to hyperoside.
Valentová
Marie
M
Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého 1/3, CZ-612 42 Brno, Czech Republic. valentovam@vfu.cz
Marek
Radek
R
Svajdlenka
Emil
E
Kubínová
Renata
R
Suchý
Václav
V
D027703:Amaranthaceae / Q000737:chemistry*; D007529:Isoflavones / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D000520:alpha-Glucosidases / Q000378:metabolism
C560469:2',2,5-trimethoxy-6,7-methylenedioxyisoflavanone; D007529:Isoflavones; D010936:Plant Extracts; D000520:alpha-Glucosidases