[Analysis of risk factors for reversible posterior leukoencephalopathy syndrome in lupus].
OBJECTIVE
To analyze the different risk factors for reversible posterior leukoencephalopathy syndrome (RPLS) in systemic lupus erythematosus (SLE).


METHODS
The clinical and imaging characteristics of 2 cases were described in details. The literature reports for 33 cases of SLE and RPLS were reviewed systematically. The etiologies of SLE and RPLS were analyzed for all 35 cases.


RESULTS
Thirty-five cases of SLE patients were complicated with RPLS, 32 cases suffered hypertension, 3 cases had no hypertension, 1 case was explicitly related with rituximab and 1 case was related with cyclosporine therapy.


CONCLUSIONS
SLE complicated by RPLS has different causes, such as hypertension, SLE involving central nervous system and drug neurotoxicity.
Department of Rheumatology & Immunology, PUMC Hospital, CAMS & PUMC, Beijing, China.
Jin-mei
JM
Su
Hua
H
Chen
Qian
Q
Wang
Guo-hua
GH
Zhang
Xiao-feng
XF
Zeng
Fu-lin
FL
Tang
D000293:Adolescent; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D054038:Posterior Leukoencephalopathy Syndrome / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors