Neurobehavioral screening in rodents.
Neurobehavioral evaluations are an important component of screening for neurotoxicological effects. A neurobehavioral test battery is chosen to assess a variety of endpoints, including autonomic, neuromuscular, sensory, and excitability functions. Such a battery includes observation of gait and posture, reactivity and arousal, gait and postural characteristics, involuntary/abnormal motor movements, clinical signs and manipulation of neurological reflexes and reactions and neuromuscular activity and postural reactions. Finally, the battery includes assessment of sensory responses.
Apex, North Carolina, USA.
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Moser
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005684:Gait / Q000187:drug effects; D009043:Motor Activity / Q000187:drug effects; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000523:psychology; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D011187:Posture; D011597:Psychomotor Performance / Q000187:drug effects; D012377:Rodentia; D018675:Toxicity Tests / Q000379:methods*