[Diabetic mastopathy: a recurrent benign breast disease].
Diabetic mastopathy is an uncommon benign entity occurring in young women with type 1 diabetes. Its clinical and radiological signs are not specific and often mimic a breast carcinoma. However, the benign nature of this lesion is easily recognized on histological examination, visualizing dense keloid-like fibrosis, lymphocytic lobulitis and ductitis with lymphocytic perivascular inflammation, with or without epithelioid-like fibroblasts. Surgery can generally be avoided. The evolution of this entity is characterized by the risk of local growth, bilateralisation or recurrence after surgical treatment. We present a case in which the core biopsy allowed the diagnosis of a diabetic mastopathy and we discuss its clinical, diagnostic, pathological and therapeutic particularities.
Département de pathologie, hôpital de Hautepierre, CHRU de Strasbourg, avenue Molière, 67200 Strasbourg cedex, France. sabrina.croce@chru-strasbourg.fr
S
S
Croce
G
G
Chaney
M-F
MF
Bretz-Grenier
A
A
Wittersheim
S
S
Casnedi
C
C
Mathelin
D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D011859:Radiography; D012008:Recurrence