Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases.
The sequence of pR3521, a self-transmissible plasmid from Escherichia coli, was determined. pR3521 (110,416 bp) comprised a contiguous IncB sequence (84,034 bp) sharing extensive similarities with IncI replicons and an acquired region (26,382 bp) carrying sequences of diverse origin, containing bla(ACC-4), bla(SCO-1), bla(TEM-1b) (two copies), strA, strB, sul2, and aacC2.
Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
C C
CC
Papagiannitsis
L S
LS
Tzouvelekis
S D
SD
Kotsakis
E
E
Tzelepi
V
V
Miriagou
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D001618:beta-Lactamases / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C034413:beta-lactamase TEM-1