Automated monitoring of hemodialysis adequacy by dialysis machines: potential benefits to patients and cost savings.
Hemodialysis adequacy can be quantified using ultraviolet absorbance of the spent dialysate, or by analysis of dialysate conductivity at the dialyzer inlet and outlet in response to changes in dialysate electrolyte concentration. These measurements can be made at every dialysis, including initial and acute treatments and can help detect access recirculation. No disposables or reagents are required. Cost may be reduced by reducing the need for blood sampling and laboratory analysis.
Department of Medicine, University of Illinois College of Medicine, Chicago, Illinois 60612-7323, USA. jtdaugir@uic.edu
John T
JT
Daugirdas
James E
JE
Tattersall
D000465:Algorithms; D057205:Automation, Laboratory; D015415:Biomarkers / Q000097:blood; D017046:Cost Savings; D004867:Equipment Design; D017048:Health Care Costs; D015312:Hemodialysis Solutions / Q000737:chemistry*; D006801:Humans; D016014:Linear Models; D008954:Models, Biological; D006435:Renal Dialysis / Q000191:economics / Q000295:instrumentation*; D015203:Reproducibility of Results; D013056:Spectrophotometry, Ultraviolet / Q000191:economics / Q000295:instrumentation*; D013997:Time Factors; D014508:Urea / Q000032:analysis* / Q000097:blood; D014511:Uremia / Q000097:blood / Q000628:therapy*
D015415:Biomarkers; D015312:Hemodialysis Solutions; D014508:Urea