Mutual benefits of B-ALL and HLDA/HCDM HLDA 9th Barcelona 2010.
The B-cell panel of the ninth HLDA was applied in a multicentre fashion to cryopreserved cells from 46 patients with acute lymphoblastic leukemia. The reagents were aliquoted and shipped to volunteer participants from the French Groupe d'Etude Immunologique des Leucémies (GEIL). All samples were tested in flow cytometry, and the results collected as of the strength of labeling of the leukemic clone as negative, weak or strong. Among the 64 antibodies tested, the strongest and most frequent staining was observed for CD305 (LAIR), CD229 (Ly9), CD200 (OX-2) and, to a lesser extent, CD361 (EVI2b). Details of the observations, and information about the molecules tested are provided in the manuscript as well as a summary table.
Faure
Gilbert C
GC
Immunology, CHU de Brabois & Nancy Université, Allée du Morvan, Vandoeuvre les Nancy, France. faure@medecine.uhp-nancy.fr
Amsellem
Sophie
S
Arnoulet
Christine
C
Bardet
Valérie
V
Campos
Lydia
L
De Carvalho-Bittencourt
Marcelo
M
de Labarthe
Adrienne
A
Eischen
Alice
A
Feuillard
Jean
J
Fossat
Chantal
C
Ottou
Francine Garnache
FG
Guérin
Estelle
E
Guy
Julien
J
Jouault
Hélène
H
Kuhlein
Emilienne
E
Lacombe
Francis
F
Lainey
Elodie
E
Maynadié
Marc
M
Noguera
Maria Elena
ME
Roussel
Mikael
M
Solly
Françoise
F
Ballon
Orianne Wagner
OW
Béné
Marie C
MC
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal / Q000276:immunology; D015703:Antigens, CD / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000276:immunology; D006801:Humans; D016130:Immunophenotyping; D007223:Infant; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology*; D055815:Young Adult
D000911:Antibodies, Monoclonal; D015703:Antigens, CD