Well-defined DNA nanoparticles templated by self-assembled M(12)L(24) molecular spheres and binding of complementary oligonucleotides.
Perfectly monodisperse DNA nanoparticles were prepared via the self-assembly of 12 Pd(II) ions and 24 bidentate ligands functionalized with oligonucleotides of varying length (n = 1-3). The DNA nanoparticles formed hydrogen bonds with cDNA strands and an insoluble aggregate formed only with matching trimeric nucleotide strands (tri-A).
Department of Applied Chemistry, School of Engineering, The University of Tokyo, and JST-CREST, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Takashi
T
Kikuchi
Sota
S
Sato
Makoto
M
Fujita
D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D008024:Ligands; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
D008024:Ligands; D009838:Oligodeoxyribonucleotides; D010165:Palladium; D004247:DNA