Platinum(II) chloride-catalyzed stereoselective domino enyne isomerization/Diels-Alder reaction.
Chiral 1,6-enynes were prepared via Ir-catalyzed allylic substitutions. Their platinum(II) chloride-catalyzed domino enyne isomerization/Diels-Alder reaction provided stereoselective access to complex heterocycles. Very high diastereoselectivity was induced by a chirality center of the enyne.
Organisch-Chemisches Institut der Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
Mathias
M
Schelwies
Andreas
A
Farwick
Frank
F
Rominger
Günter
G
Helmchen