The impact of demographic characteristics and lifestyle in the distribution of cystatin C values in a healthy greek adult population.
Background. The aim of the present study was to examine sources of variation for serum cystatin C in a healthy Greek population. Methods. Cystatin C together with basic clinical chemistry tests was measured in a total of 490 adults (46 ± 16 yrs, 40% males) who underwent an annual health check. Demographic, anthropometric, and lifestyle characteristics were recorded. Results. Higher values of cystatin C were observed among males (P = .04), participants aged over 65 years (P < .001), current smokers (P = .001) and overweight/obese participants (P = .03). On the contrary, alcohol consumption and physical activity seemed to have no influence on cystatin C levels (P = .61; P = .95, resp.). Conclusions. In interpreting serum cystatin C values in a healthy adult population, age, gender, Body Mass Index, and cigarette smoking need to be considered, and determination of reference ranges among distinct subpopulations seem to be prudent.
Evangelopoulos
Angelos A
AA
Department of Internal Medicine, Polykliniki General Hospital, 10552 Athens, Greece.
Vallianou
Natalia G
NG
Bountziouka
Vassiliki P
VP
Giotopoulou
Amalia N
AN
Bonou
Maria S
MS
Barbetseas
John
J
Avgerinos
Peter C
PC
Panagiotakos
Demosthenes B
DB