The aromatic carbon-carbon ipso-substitution reaction.
The aim of this review is to illustrate what we have dubbed an aromatic carbon-carbon ipso-substitution reaction in which a new Ar-C bond is formed at the expense of another Ar-C bond. The potentiality of several C-based leaving groups including alkyl, carbinol, CN, COOH, and carbonyl groups in arylation reactions will be illustrated accordingly for the preparation of biphenyl-, vinyl-, alkynyl-, and alkyl-substituted aromatics.
CIHIDECAR-CONICET, Departamento de Química Orgánica, 3er Piso, Pabellón 2, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, CP1428, Universidad de Buenos Aires, Argentina.
Sergio M
SM
Bonesi
Maurizio
M
Fagnoni