Recent advances in diagnosis and treatment of atypical haemolytic uraemic syndrome.
New understanding of the underlying pathology of the thrombotic microangiopathies has resulted in guidelines for the investigation and management of atypical haemolytic uraemic syndrome in children and adults and the prospect of new therapies, which are in clinical trial. Patients should be investigated for defects in complement pathways and a trial of plasma exchange is indicated.
Bolton-Maggs
Paula Hb
PH
Department of Clinical Haematology, Manchester Royal Infirmary Oxford Road, Manchester, M13 9WL UK.