REDfly v3.0: toward a comprehensive database of transcriptional regulatory elements in Drosophila.
The REDfly database of Drosophila transcriptional cis-regulatory elements provides the broadest and most comprehensive available resource for experimentally validated cis-regulatory modules and transcription factor binding sites among the metazoa. The third major release of the database extends the utility of REDfly as a powerful tool for both computational and experimental studies of transcription regulation. REDfly v3.0 includes the introduction of new data classes to expand the types of regulatory elements annotated in the database along with a roughly 40% increase in the number of records. A completely redesigned interface improves access for casual and power users alike; among other features it now automatically provides graphical views of the genome, displays images of reporter gene expression and implements improved capabilities for database searching and results filtering. REDfly is freely accessible at http://redfly.ccr.buffalo.edu.
Center for Computational Research, New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York, Buffalo, NY 14203, USA.
Steven M
SM
Gallo
Dave T
DT
Gerrard
David
D
Miner
Michael
M
Simich
Benjamin
B
Des Soye
Casey M
CM
Bergman
Marc S
MS
Halfon
D000818:Animals; D001665:Binding Sites; D030541:Databases, Genetic; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000235:genetics*; D050436:Regulatory Elements, Transcriptional; D012984:Software; D026801:Synteny; D014157:Transcription Factors / Q000378:metabolism*; D014584:User-Computer Interface
D029721:Drosophila Proteins; D014157:Transcription Factors