Tetrasubstituted furans by Pd(II)/Cu(I)-cocatalyzed three-component domino reactions of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts.
A novel Pd(OAc)(2)/CuI-cocatalyzed three-component reaction of 2-(1-alkynyl)-2-alken-1-ones, nucleophiles and diaryliodonium salts has been developed. The procedure allows the synthesis of tetrasubstituted furans in good to high yields under mild conditions.
Li
Wenbo
W
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, PR China.
Zhang
Junliang
J
D000085:Acetates / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D013237:Stereoisomerism
D000085:Acetates; D000475:Alkenes; D005663:Furans; D006847:Hydrocarbons, Iodinated; D007454:Iodides; D009942:Organometallic Compounds; D012492:Salts; C516071:palladium(II) acetate; D003300:Copper; C073870:cuprous iodide