Advantages and disadvantages of the use of bisphosphonates in oral and maxillofacial surgery.
Bisphosphonates are a class of drugs of proven efficacy in the prevention and treatment of various bone diseases, affecting bone turnover by decreasing bone resorption by different mechanisms. In recent years, this class of drugs has become the target of numerous studies in relation to oral and maxillofacial surgery. The aim of this paper is to review the literature on the effects of bisphosphonates in this context, especially in the development of osteonecrosis and as adjuvant in implant placement, osteogenic distraction and bone grafting surgery.
de Souza Loureiro
Caio Cesar
CC
Brazilian Society of Oral & Maxillofacial Surgery (SOBRACIBU). csloureiro@gmail.com
Leandro
Luiz Fernando Lobo
LF
D050071:Bone Density Conservation Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D004164:Diphosphonates / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced; D019647:Oral Surgical Procedures; D019857:Osteogenesis, Distraction; D010020:Osteonecrosis / Q000139:chemically induced
D050071:Bone Density Conservation Agents; D004164:Diphosphonates