When transcription meets recombination: a lesson from the human RECQ protein complexes.
Since the cloning of the first human RECQ gene, RECQ1, more than 15 years ago, RECQ helicases have been a major focus in cancer research. Recent studies of human RECQ protein complexes are providing insight into their roles in various DNA metabolic pathways that protect the integrity of our genome.
Liu
Yilun
Y
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520-8040, USA. yilun.liu@yale.edu
Conaway
Joan W
JW