Superquenching acridinium ester chemiluminescence by gold nanoparticles for DNA detection.
It was found that the chemiluminescence of acridinium ester (AE) was quenched effectively by gold nanoparticles (AuNPs) with Stern-Volmer constants approaching 10(10) M(-1), which was exploited to realize sequence-specific DNA detection based on the preferential absorption of AE-tagged single-strand probe on unmodified AuNPs over the hybrids of probe and target DNA.
Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.
Qinfeng
Q
Xu
Jing
J
Liu
Zhike
Z
He
Si
S
Yang
D000166:Acridines / Q000737:chemistry*; D001483:Base Sequence; D004247:DNA / Q000032:analysis*; D004952:Esters / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D049449:Luminescence; D053768:Metal Nanoparticles / Q000737:chemistry*
D000166:Acridines; D004952:Esters; D006046:Gold; D004247:DNA