Comparison of left ventricular diastolic parameters between patients with and without significant mitral regurgitation.
Mitral regurgitation (MR) can affect left ventricular diastolic parameters because of interference with regurgitation flow. This study compared left ventricular diastolic parameters between patients with and without significant MR. The MR group included 57 consecutive patients with significant MR. Fifty-seven age-, sex- and Tei index-matched patients without significant MR were selected as the reference group. Baseline characteristics and Tei index and its components were comparable between the MR and reference groups. The MR group had higher left atrial volume index, transmitral E wave velocity (E), ratio of E to transmitral A wave velocity, early diastolic mitral annular velocity (Ea), E/Ea, and ratio of E to isovolumic relaxation flow propagation velocity (IRFPV) (p ≤ 0.025), and lower E-wave deceleration time (p = 0.019) and late diastolic mitral annular velocity (p < 0.001). However, the two groups had similar IRFPV (p = 0.844). In conclusion, MR apparently affects E and Ea, but not IRFPV. IRFPV could potentially be a reliable relaxation parameter in patients with significant MR, but further confirmation by invasive studies is needed.
Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan.
Ho-Ming
HM
Su
Tsung-Hsien
TH
Lin
Chee-Siong
CS
Lee
Po-Chao
PC
Hsu
Wei-Chung
WC
Tsai
Chun-Yuan
CY
Chu
Wen-Ter
WT
Lai
Sheng-Hsiung
SH
Sheu
Wen-Chol
WC
Voon
D003971:Diastole / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014463:Ultrasonography; D016277:Ventricular Function, Left / Q000502:physiology*