[Effect of chronoexercise on circadian expression of clock genes].
OBJECTIVE
To investigate the molecular biological mechanism of chronoexercise regulating circadian.


METHODS
Expressions of mPer1 and mPer2 in the diencephalon of golden hamster were determined 2 hours after acute exhaustive exercise (circadian time 6) by quantitative RT-PCR.


RESULTS
Chronoexercise at CT6 significantly decreased expressions of mPer1 and mPer2 in the diencephalon of golden hamster.


CONCLUSIONS
Inhibitory effect of chronoexercise on Per1 and Per2 mRNA levels in the diencephalon of golden hamster at CT6 may be achieved transcription-translation-based autoregulatory negative feedback loop.
PLA Institute of Physical Education, Guangzhou 510502, China. jianman00006@yahoo.com
Kun-lin
KL
Jian
Ying
Y
Xu
Xiang-qian
XQ
Wang
Dong-sheng
DS
Ai
Li
L
Liu
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D006224:Cricetinae; D015870:Gene Expression; D056950:Period Circadian Proteins / Q000235:genetics / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
D056950:Period Circadian Proteins; D012333:RNA, Messenger