Prescription drug misuse among antisocial youths.
OBJECTIVE
The aim of this study was to describe the prevalence and correlates of nonmedical prescription drug misuse (PDM) in a state population of youths in residential care for antisocial behavior.


METHODS
Interviews assessing substance use, psychiatric symptoms, antisocial traits/behavior, and traumatic life experiences were conducted with 723 Missouri youths. Participants were predominantly male (87.0%), averaged 15.5 (SD = 1.2) years of age, and constituted 97.7% of the service population sampled.


RESULTS
Overall, 314 youths (43.4%) reported lifetime PDM; 33.7%, 32.0%, and 11.2% had misused prescription opioids, tranquilizers, and barbiturates, respectively. Prescription drug misusers were significantly older, and larger proportions were girls, were White, and resided in small towns, compared with non-prescription drug misusers. Prescription drug misusers evidenced significantly more varied, frequent, and problematic psychoactive drug use; evidenced higher levels of distressing psychiatric symptoms; and were nearly twice as likely to have been diagnosed with a psychiatric disorder, compared with non-prescription drug misusers. Traumatic life events, experiences of criminal victimization, and suicidal ideation were significantly more prevalent in the histories of prescription drug misusers, compared with non-prescription drug misusers. In multiple logistic regression models, older age; White racial status; prior inhalant, marijuana, and LSD (lysergic acid diethylamide) use; residence in a small town; and impulsivity were associated with increased risk for PDM.


CONCLUSIONS
Adolescents in residential care for antisocial behavior have high rates of PDM, as well as comorbid psychiatric and behavioral problems. Youths served in institutional settings should be routinely screened and treated for PDM and co-occurring disorders.
Hall
Martin T
MT
Department of Behavioral Science, 122 Medical Behavioral Science Building, University of Kentucky, Lexington, Kentucky 40536-0086, USA. martin.hall@uky.edu
Howard
Matthew O
MO
McCabe
Sean Esteban
SE
D000293:Adolescent; D000987:Antisocial Personality Disorder / Q000150:complications / Q000453:epidemiology* / Q000523:psychology*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D055553:Prescription Drugs / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000150:complications / Q000453:epidemiology* / Q000523:psychology*; D055815:Young Adult
D055553:Prescription Drugs