Increased risk for acute lymphoblastic leukemia in children with cytochrome P450A1 (CYP1A1)- and NAD(P)H:quinone oxidoreductase 1 (NQO1)-inherited gene variants.
Clinical Oncology Service, Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Gabriela G
GG
Yamaguti
Gustavo J
GJ
Lourenço
Vanessa S
VS
Silveira
Luiz G
LG
Tone
Luiz F
LF
Lopes
Carmen S P
CS
Lima
D001938:Brazil; D016022:Case-Control Studies; D002675:Child, Preschool; D019363:Cytochrome P-450 CYP1A1 / Q000235:genetics*; D004785:Environmental Pollutants / Q000378:metabolism / Q000633:toxicity; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008658:Inactivation, Metabolic / Q000235:genetics / Q000502:physiology; D007223:Infant; D008297:Male; D008875:Middle Aged; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000235:genetics*; D011084:Polycyclic Aromatic Hydrocarbons / Q000378:metabolism / Q000633:toxicity; D020641:Polymorphism, Single Nucleotide; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000201:enzymology* / Q000209:etiology / Q000235:genetics*; D012307:Risk Factors
D004785:Environmental Pollutants; D011084:Polycyclic Aromatic Hydrocarbons; D019363:Cytochrome P-450 CYP1A1; D016660:NAD(P)H Dehydrogenase (Quinone); C447479:NQO1 protein, human