Primary central nervous system T-cell lymphoma in aids patients: case report and literature review.
According to the published data, most primary central nervous system lymphomas (PCNSLs) are B-cell lymphomas; primary T-cell lymphomas are rare. In a search of the MEDLINE database, we found only 6 cases of primary T-cell PCNSL. Here, we present the case of a 43-year-old man with AIDS, not on highly active antiretroviral therapy, who presented with focal neurologic symptoms and was found on magnetic resonance imaging to have multiple brain lesions. A biopsy showed T-cell lymphoma, and the patient was subsequently treated with whole-brain radiation, to marked clinical response. Reported cases from the literature of primary T-cell PCNSL in AIDS patients are summarized in this review.
Department of Internal Medicine, Saint Joseph Hospital and University of Illinois at Chicago, Chicago, IL, U.S.A.
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S
Latta
Z W
ZW
Myint
B
B
Jallad
T
T
Hamdi
M N
MN
Alhosaini
D V
DV
Kumar
F
F
Kheir