Applications of high-throughput sequencing to chromatin structure and function in mammals.
High-throughput DNA sequencing approaches have enabled direct interrogation of chromatin samples from mammalian cells. We are beginning to develop a genome-wide description of nuclear function during development, but further data collection, refinement, and integration are needed.
Dunham
Ian
I
EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton Cambridge CB10 1SD UK. dunham@ebi.ac.uk