Treatment of acute carbon-monoxide poisoning with therapeutic erythrocytapheresis: clinical effects and results in 17 victims.
Seventeen cases of acute carbon-monoxide poisoning were treated with therapeutic red cell-exchange. Glasgow Coma Scale score was used to evaluate the level of consciousness. The mean carboxyhemoglobin level decreased from 0.286 ± 0.1805 (28.6 ± 18.05%) to 0.0613 ± 0.0418 (6.13 ± 4.18%) and Glasgow Coma Scale score increased from 10 ± 3 to 13.76 ± 1.89. While 11 patients scored 15 at the end of the treatment, four scored 15 in an hour after the treatment. None of the patients died. Two victims (11.7%) experienced ischemic encephalopathy. Therapeutic red cell-exchange therapy can be an effective treatment in reducing mortality and morbidity in carbon-monoxide poisoning.
Department of Emergency, Faculty of Medicine, University of Cukurova, 01330 Adana, Turkey.
Alper
A
Celikdemir
Department of Emergency, Faculty of Medicine, University of Cukurova, 01330 Adana, Turkey. Electronic address: ygokel@cu.edu.tr.
Yuksel
Y
Gokel
Department of Hematology, Faculty of Medicine, University of Cukurova, 01330 Adana, Turkey.
Birol
B
Guvenc
Department of Apheresis, Faculty of Medicine, University of Cukurova, 01330 Adana, Turkey.
Ferda
F
Tekinturan
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000209:etiology; D002249:Carbon Monoxide Poisoning / Q000628:therapy*; D002263:Carboxyhemoglobin; D003243:Consciousness; D016238:Cytapheresis; D017707:Erythrocyte Transfusion / Q000009:adverse effects / Q000379:methods*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
D002263:Carboxyhemoglobin