Lifetime risk of undergoing surgery for pelvic organ prolapse.
OBJECTIVE
To investigate the lifetime risk of first-time incident pelvic organ prolapse (POP) surgery with the intention of updating previous risk estimates that have been based on members of managed-care populations.


METHODS
Age-specific incidence rates of first-time prolapse surgery between 1981 and 2005 were calculated based on 44,728-incident cases. We estimated the lifetime risk as the cumulative incidence to age 85 years based on a life-table method and using the most recent cross-sectional incidence rates for the period 2001-2005. Age-standardized rates by calendar year were also calculated to show the secular trend in prolapse surgery.


RESULTS
The lifetime risk of surgery for POP in the general female population was 19% based on the most recent cross-sectional rates, a figure higher than the 11-12% reported from U.S. managed-care populations.


CONCLUSIONS
There is a relatively high likelihood that a woman in Western Australia will undergo surgery for POP during her lifetime. If, as our results suggest, the burden of genital prolapse in general populations is higher than previously thought, there is justification for a stronger evidence base for prevention, early detection and intervention to reduce the personal and societal costs of these gynecological conditions.


METHODS
II.
Centre for Health Services Research, School of Population Health, The University of Western Australia, Perth, Australia. fsmith@meddent.uwa.edu.au
Fiona J
FJ
Smith
C D'Arcy J
CD
Holman
Rachael E
RE
Moorin
Nicolas
N
Tsokos
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000453:epidemiology / Q000601:surgery*; D012306:Risk; D014904:Western Australia / Q000453:epidemiology; D055815:Young Adult