Capturing the dynamic epigenome.
Traditional methods for epigenomic analysis provide a static picture of chromatin, which is actually a highly dynamic assemblage. Recent approaches have allowed direct measurements of chromatin dynamics, providing deeper insights into processes such as transcription, DNA replication and epigenetic inheritance.
Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Roger B
RB
Deal
Steven
S
Henikoff
D002843:Chromatin / Q000235:genetics*; D019175:DNA Methylation; D004261:DNA Replication; D044127:Epigenesis, Genetic; D057890:Epigenomics / Q000379:methods*; D036681:Fluorescence Recovery After Photobleaching / Q000379:methods; D006657:Histones / Q000032:analysis / Q000235:genetics; D017422:Sequence Analysis, DNA; D014157:Transcription Factors / Q000235:genetics; D019076:Transgenes
D002843:Chromatin; D006657:Histones; D014157:Transcription Factors