The Pancreatic Expression database: 2011 update.
The Pancreatic Expression database (PED, http://www.pancreasexpression.org) has established itself as the main repository for pancreatic-derived -omics data. For the past 3 years, its data content and access have increased substantially. Here we describe several of its new and improved features, such as data content, which now includes over 60,000 measurements derived from transcriptomics, proteomics, genomics and miRNA profiles from various pancreas-centred reports on a broad range of specimen and experimental types. We also illustrate the capabilities of its interface, which allows integrative queries that can combine PED data with a growing number of biological resources such as NCBI, Ensembl, UniProt and Reactome. Thus, PED is capable of retrieving and integrating different types of -omics, annotations and clinical data. We also focus on the importance of data sharing and interoperability in the cancer field, and the integration of PED into the International Cancer Genome Consortium (ICGC) data portal.
Centre for Molecular Oncology and Imaging, Institute of Cancer and CR-UK Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Rosalind J
RJ
Cutts
Emanuela
E
Gadaleta
Stephan A
SA
Hahn
Tatjana
T
Crnogorac-Jurcevic
Nicholas R
NR
Lemoine
Claude
C
Chelala
D000818:Animals; D030541:Databases, Genetic; D015870:Gene Expression; D020869:Gene Expression Profiling; D023281:Genomics; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000235:genetics* / Q000378:metabolism; D040901:Proteomics; D014584:User-Computer Interface
D035683:MicroRNAs