Laparoscopic posterior exenteration in advanced gynecologic malignant disease.
OBJECTIVE
To study the feasibility, morbidity, and oncologic outcome of laparoscopic posterior exenteration in patients with advanced gynecologic malignant diseases.


METHODS
Retrospective study based on clinical experience (Canadian Task Force classification III).


METHODS
Private hospital.


METHODS
The medical records for 10 patients who underwent laparoscopic posterior exenteration because of advanced gynecologic malignant disease were retrospectively reviewed.


METHODS
Laparoscopic posterior exenteration involving selective resection of the uterus, ovaries, vagina, and rectum was performed using a 6-port technique that included harmonic shears, the LigaSure device, and a circular endostapling instrument.


RESULTS
Histopathologic diagnosis included carcinoma of the cervix in 5 patients, ovary in 4 patients, and vagina in 1 patient. Indication for surgery was primary disease in 7 patients and secondary disease in 3 patients. Complications included delayed bladder recovery in 4 patients, and anastomotic leak, wound infection, and prolonged ileus in 1 patient each. No conversions to open surgery were required. The extent of resection was supralevator in 8 patients and infralevator in 2. Median operative time was 210 minutes. Median length of hospital stay was 9 days. Median blood loss was 360 mL. Disease recurred in 1 patient. After a median follow-up of 26 months, 9 patients were alive, and 8 were free of disease.


CONCLUSIONS
Laparoscopic posterior exenteration is feasible in advanced gynecologic malignant disease with rectal involvement. In addition to the known benefits of laparoscopic surgery, carefully selected patients could achieve a survival benefit following R0 resection.
Department of Minimally Invasive Surgical Oncology, Galaxy Care Laparoscopy Institute, Pune, India. shase63@gmail.com
Shailesh
S
Puntambekar
Saravana
S
Rajamanickam
Geetanjali
G
Agarwal
Saurabh
S
Joshi
Neeraj
N
Rayate
Avanish
A
Deshmukh
D000328:Adult; D005240:Feasibility Studies; D005260:Female; D005833:Genital Neoplasms, Female / Q000601:surgery*; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D010385:Pelvic Exenteration / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome