MRI in diagnosis of orbital masses.
OBJECTIVE
To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging.


METHODS
The study included 32 patients presenting with proptosis. Every patient was subjected to a clinical examination; conventional MRI "T1 weighted, T2 weighted, and post-contrast T1 weighted if needed;" diffusion-weighted MRI; and proton magnetic resonance spectroscopy. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed.


RESULTS
Diffusion-weighted MRI can be used to differentiate between benign lesions and malignant tumors in 75% of cases; however, overlap occurred in 25% of cases with benign tumors showing restricted diffusion while proton magnetic resonance spectroscopy could differentiate between benign and malignant tumors in 93.7% of cases.


CONCLUSIONS
Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.
Mansoura Ophthamic Center, Mansoura University, Mansoura, Egypt.
Nader
N
Roshdy
Maha
M
Shahin
Hanem
H
Kishk
Asaad A
AA
Ghanem
Sherif
S
El-Khouly
Amany
A
Mousa
Iman
I
Elsalekh
D000230:Adenocarcinoma / Q000175:diagnosis; D000328:Adult; D005094:Exophthalmos / Q000175:diagnosis; D005142:Eyelid Neoplasms / Q000175:diagnosis; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis; D008223:Lymphoma / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008537:Meibomian Glands / Q000473:pathology; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000601:surgery; D011522:Protons; D012208:Rhabdomyosarcoma / Q000175:diagnosis
D011522:Protons