Superquenching acridinium ester chemiluminescence by gold nanoparticles for DNA detection.
It was found that the chemiluminescence of acridinium ester (AE) was quenched effectively by gold nanoparticles (AuNPs) with Stern-Volmer constants approaching 10(10) M(-1), which was exploited to realize sequence-specific DNA detection based on the preferential absorption of AE-tagged single-strand probe on unmodified AuNPs over the hybrids of probe and target DNA.
Xu
Qinfeng
Q
Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.
Liu
Jing
J
He
Zhike
Z
Yang
Si
S
D000166:Acridines / Q000737:chemistry*; D001483:Base Sequence; D004247:DNA / Q000032:analysis*; D004952:Esters / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D049449:Luminescence; D053768:Metal Nanoparticles / Q000737:chemistry*
D000166:Acridines; D004952:Esters; D006046:Gold; D004247:DNA