Distribution of neuropeptides in endocrine and exocrine pancreas of long-legged buzzard (Buteo rufinus): an immunohistochemical study.
This study aimed to determine the existence and distribution of certain neuropeptides in endocrine and exocrine pancreas of the long-legged buzzard by using immunohistochemical methods. SOM-14-, NPY- and CGRP-IR endocrine cells were determined in both central and peripheral regions in A-islets within the pancreas, while SP-IR endocrine cells were found only in the central region, and CCK-8- and galanin-IR endocrine cells were only detected in peripheral region. On the other hand, in B-islets; SP-, NPY- and CGRP-IRendocrine cells were determined in both central and peripheral regions, while SOM-14- CCK-8- and galanin-IRendocrine cells were found only in the peripheral region. In addition; SOM-14-, NPY-, CGRP-, CCK-8- and galanin-IR cells were also observed in exocrine pancreas. This distribution pattern in the pancreas of the long-legged buzzard demonstrates that neuropeptides perform their probable affects through endocrine and/or paracrine mechanisms. In conclusion, the existence and distribution of neuropeptides in the pancreas of long-legged buzzard have been introduced in this study for the first time and this bird species has also been found to differ from other types of avian species.
Bayrakdar
Ali
A
Department of Histology and Embryology, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey. alibayrakdar@firat.edu.tr
Yaman
Mine
M
Atalar
Omer
O
Gencer Tarakci
Berrin
B
Ceribasi
Songul
S
D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism; D046093:Falconiformes; D019004:Galanin / Q000378:metabolism; D007150:Immunohistochemistry; D007515:Islets of Langerhans / Q000737:chemistry; D008297:Male; D009478:Neuropeptide Y / Q000378:metabolism; D009479:Neuropeptides / Q000378:metabolism*; D010179:Pancreas / Q000737:chemistry*; D046790:Pancreas, Exocrine / Q000737:chemistry*; D012844:Sincalide / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism; D013373:Substance P / Q000378:metabolism
D009478:Neuropeptide Y; D009479:Neuropeptides; D013373:Substance P; D013004:Somatostatin; D019004:Galanin; D015740:Calcitonin Gene-Related Peptide; D012844:Sincalide