Decreasing systolic blood pressure is associated with improving estimated glomerular filtration rate (eGFR) with lifestyle modification in Japanese healthy women.
The link between changes in a subject's metabolic syndrome components and her estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese women. We used data for 53 Japanese women (46.0±10.9 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant relationships between eGFR and clinical parameters at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, eGFR was significantly increased. In addition, changes in eGFR were weakly correlated with systolic blood pressure(r=-0.306, p=0.0260). A decrease in systolic blood pressure may be associated with improving eGFR in Japanese women.
Department of Hygiene, Faculty of Medicine, Kagawa University, Miki, Kagawa 761-0793, Japan. miyarin@med.kagawa-u.ac.jp
Nobuyuki
N
Miyatake
Kenichi
K
Shikata
Hirofumi
H
Makino
Takeyuki
T
Numata
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology*; D001823:Body Composition / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate / Q000502:physiology*; D006801:Humans; D007564:Japan; D008019:Life Style; D008055:Lipids / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D013599:Systole / Q000502:physiology
D001786:Blood Glucose; D008055:Lipids