Sialolipoma of minor salivary glands.
Sialolipoma is a recently described histologic variant of lipoma and is characterized by well-demarcated proliferation of mature adipocytes with secondary entrapment of salivary gland elements. These tumors have been observed in both the major and minor salivary glands, with more than 20 cases being reported in the English literature. In general, the clinical presentation of sialolipomas of the minor salivary glands suggests a diagnostic hypothesis of salivary gland lesions, commonly neoplasms. In the major salivary glands, the clinical features suggest either a salivary gland neoplasm or a lipoma. Surgical excision is the treatment of choice for sialolipomas, with no reports of recurrence or malignant transformation. The present article reports 4 additional cases of sialolipoma, all of them affecting the minor salivary glands, and reviews the literature regarding clinicopathologic aspects, differential diagnosis, and therapeutic management of this recently recognized histologic variant of lipoma.
Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, CEP: 59056-000, Natal, RN, Brazil.
Cassiano Francisco Weege
CF
Nonaka
Karuza Maria Alves
KM
Pereira
Pedro Paulo
PP
de Andrade Santos
Roseana
R
de Almeida Freitas
Márcia Cristina
MC
da Costa Miguel
D017667:Adipocytes / Q000473:pathology; D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008067:Lipoma / Q000473:pathology* / Q000601:surgery; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D012470:Salivary Glands, Minor / Q000473:pathology