A combined mechanistic and computational study of the gold(I)-catalyzed formation of substituted indenes.
Substituted indenes can be prepared after a sequence [1,3] O-acyl shift-hydroarylation-[1,3] O-acyl shift. Each step is catalyzed by a cationic NHC-Gold(I) species generated in situ after reaction between [(IPr)AuOH] and HBF(4)·OEt(2). This interesting silver-free way is fully supported by a computational study justifying the formation of each intermediate.
EasStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews, UK KY16 9ST.
Pierrick
P
Nun
Sylvain
S
Gaillard
Albert
A
Poater
Luigi
L
Cavallo
Steven P
SP
Nolan