Homozygous mutation in SCN5A associated with atrial quiescence, recalcitrant arrhythmias, and poor capture thresholds.
Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030, USA. knlopez@bcm.edu
Keila N
KN
Lopez
Jamie A
JA
Decker
Richard A
RA
Friedman
Jeffrey J
JJ
Kim
D000638:Amiodarone / Q000008:administration & dosage; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage; D001145:Arrhythmias, Cardiac / Q000235:genetics*; D002304:Cardiac Pacing, Artificial; D016887:Cardiopulmonary Resuscitation; D002648:Child; D004200:Diseases in Twins / Q000235:genetics*; D004562:Electrocardiography; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006325:Heart Atria / Q000503:physiopathology*; D006720:Homozygote; D006801:Humans; D062554:NAV1.5 Voltage-Gated Sodium Channel; D012008:Recurrence; D015222:Sodium Channels / Q000235:genetics*; D017180:Tachycardia, Ventricular / Q000235:genetics / Q000628:therapy
D000889:Anti-Arrhythmia Agents; D062554:NAV1.5 Voltage-Gated Sodium Channel; C568320:SCN5A protein, human; D015222:Sodium Channels; D000638:Amiodarone