Microsurgical management of tuberculum sellae meningiomas by the frontolateral approach: surgical technique and visual outcome.
OBJECTIVE
The aim of this study was to evaluate visual outcome in patients with tuberculum sellae meningioma (TSM) treated microsurgically using the frontolateral or fronto-orbital approach and optic canal unroofing to resect tumor involvement of the optic canal.


METHODS
Data from 67 patients with TSMs who underwent microsurgical treatment by a frontolateral approach (n=44) or fronto-orbital approach (n=23) between January 2002 and December 2008 were retrospectively collected and analyzed. Change in visual function was evaluated as the main outcome.


RESULTS
Total tumor resection was achieved in 62 of 67 cases (92.4%). Postoperative, visual acuity was improved in 87 eyes (64.9%) and unchanged in 39 eyes (29.1%), and the optic nerve was therefore preserved in 126 of 134 eyes (94.0%). Visual field deficits were improved or stable in 65 eyes, no patient experienced worsening of vision in both eyes. There was no mortality in our series.


CONCLUSIONS
The frontolateral approach with microsurgical dissection of the Sylvian fissure provides quick access to TSMs, which can be resected safely and totally. Visual function is improved and neurological and ophthalmological morbidity is minimal. Optic nerve decompression by intradural clinoidectomy and optic canal unroofing is likely to increase the rate of reducing or eliminating preoperative visual symptoms.
Department of Neurosurgery, Xuanwu Hospital, The Capital Medical University, Chuangchu Street 45, Beijing 100053, China. chenlihuallx@yahoo.com.cn
Chen
C
Li-Hua
Chen
C
Ling
Liu
L
Li-Xu
D000328:Adult; D000368:Aged; D003399:Craniotomy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008866:Microsurgery; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D009897:Optic Chiasm / Q000098:blood supply; D009900:Optic Nerve / Q000098:blood supply / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology; D012039:Regional Blood Flow / Q000502:physiology; D012886:Skull / Q000601:surgery*; D012888:Skull Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D013100:Sphenoid Bone / Q000473:pathology* / Q000601:surgery*; D013525:Surgical Instruments; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology / Q000628:therapy*; D014785:Vision, Ocular / Q000502:physiology; D014792:Visual Acuity