Genome-wide patterns of genetic variation among elite maize inbred lines.
We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.
Lai
Jinsheng
J
State Key Lab of Agrobiotechnology, China Agricultural University, Beijing, China.
Li
Ruiqiang
R
Xu
Xun
X
Jin
Weiwei
W
Xu
Mingliang
M
Zhao
Hainan
H
Xiang
Zhongkai
Z
Song
Weibin
W
Ying
Kai
K
Zhang
Mei
M
Jiao
Yinping
Y
Ni
Peixiang
P
Zhang
Jianguo
J
Li
Dong
D
Guo
Xiaosen
X
Ye
Kaixiong
K
Jian
Min
M
Wang
Bo
B
Zheng
Huisong
H
Liang
Huiqing
H
Zhang
Xiuqing
X
Wang
Shoucai
S
Chen
Shaojiang
S
Li
Jiansheng
J
Fu
Yan
Y
Springer
Nathan M
NM
Yang
Huanming
H
Wang
Jian
J
Dai
Jingrui
J
Schnable
Patrick S
PS
Wang
Jun
J
D032461:Chromosomes, Plant / Q000235:genetics; D018744:DNA, Plant / Q000235:genetics; D017343:Genes, Plant / Q000235:genetics; D014644:Genetic Variation; D055106:Genome-Wide Association Study; D007178:Inbreeding; D020641:Polymorphism, Single Nucleotide; D003313:Zea mays / Q000235:genetics*
D018744:DNA, Plant