Versatile functionalization of nanoelectrodes by oligonucleotides via pyrrole electrochemistry.
Surface modification at the nanometer scale is a challenge for the future of molecular electronics. In particular, the precise anchoring and electrical addressing of biological scaffolds such as complex DNA nanonetworks is of importance for generating bio-directed assemblies of nano-objects for nanocircuit purposes. Herein, we consider the individual modification of nanoelectrodes with different oligonucleotide sequences by an electrochemically driven co-polymerization process of pyrrole and modified oligonucleotide sequences bearing pyrrole monomers. We demonstrate that this one-step technique presents the advantages of simplicity, localization of surface modification, mechanical, biological and chemical stability of the coatings, and high lateral resolution.
INAC-SPrAM-CREAB (UMR 5819 CNRS-CEA-Université Joseph Fourier), CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble cedex 9, France.
Emeline
E
Descamps
Khoa
K
Nguyen
Christelle
C
Bouchain-Gautier
Arianna
A
Filoramo
Laurence
L
Goux-Capes
Marcello
M
Goffman
Jean-Philippe
JP
Bourgoin
Pascal
P
Mailley
Thierry
T
Livache
D001483:Base Sequence; D055664:Electrochemical Techniques; D008839:Microelectrodes; D018625:Microscopy, Atomic Force; D036103:Nanotechnology; D009841:Oligonucleotides / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*
D009841:Oligonucleotides; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole