[Serum levels of macrophage migration inhibitory factor and leptin in patients with acute trichinellosis].
The aim of this study was to examine the serum levels of MIF and leptin in patients infected with Trichinella britovi. Thirtysix patients with acute trichinellosis and 20 healthy control subjects were included in the study. Serum high sensitive C-reactive protein (hs-CRP), MIF and leptin levels were studied. Assessments were performed in the patients group during acute infection and after the treatment periods and we also compared these values with healthy controls. In the patients, hs-CRP, leukocyte and eosinophil counts, and the levels of muscle enzymes in the acute infectious period were found to be significantly higher than those in the post treatment period (p < 0.05). Both leptin and MIF were higher in acute trichinellosis patients when compared to controls. However, this was only significant for leptin. This study indicates that leptin and MIF levels are increased in the sera of patients with acute trichinellosis.
Adnan Menderes University, Faculty of Medicine, Department of Biochemistry, Aydın, Türkiye, Turkey. idkozaci@yahoo.com
Leyla Didem
LD
Kozaci
Ismail
I
Sari
Servet
S
Akar
Merih
M
Bırlık
Nurullah
N
Akkoç
Ian C
IC
Chikanza
Fatoş
F
Onen
D000208:Acute Disease; D000328:Adult; D001219:Aspartate Aminotransferases / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D016022:Case-Control Studies; D003402:Creatine Kinase / Q000097:blood; D004196:Disease Outbreaks; D004804:Eosinophils / Q000166:cytology; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D020738:Leptin / Q000097:blood*; D007958:Leukocyte Count; D008263:Macrophage Migration-Inhibitory Factors / Q000097:blood*; D008297:Male; D012709:Serum Albumin / Q000032:analysis; D014235:Trichinellosis / Q000097:blood* / Q000453:epidemiology; D014421:Turkey / Q000453:epidemiology
D020738:Leptin; D008263:Macrophage Migration-Inhibitory Factors; D012709:Serum Albumin; D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase