Management of dyslipidemia in the elderly population.
The elderly population is increasing worldwide. Despite a major decrease in deaths from coronary heart disease (CHD), this malady remains the major cause of death in elderly men and women. In this paper, we review the role of dyslipidemia as a major known risk factor in the pathogenesis of CHD, age-related changes in lipoprotein metabolism, and differences in changes in lipids that occur in men and women during aging. Next we provide an overview of the available studies and recommendations from ATP III. Finally, we comment on the screening and management, cost and side effects of therapy as it applies to an aging population.
Gobal
Freij A
FA
Department of Internal Medicine and Physiology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.
Mehta
Jawahar L
JL
D000367:Age Factors; D000368:Aged; D000818:Animals; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D050171:Dyslipidemias / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D000960:Hypolipidemic Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use; D008074:Lipoproteins / Q000378:metabolism*; D008297:Male; D008403:Mass Screening / Q000379:methods; D012307:Risk Factors; D012737:Sex Factors
D000960:Hypolipidemic Agents; D008074:Lipoproteins