AA type renal amyloidosis secondary to FMF: a long-term follow-up in two patients.
Renal amyloidosis, which leads to renal failure, is the most important long-term complication of familial Mediterranean fever (FMF). Resolution of nephrotic syndrome secondary to amyloidosis in FMF following colchicine treatment has rarely been reported. We describe two patients with FMF and nephrotic syndrome. These patients were treated with colchicine 1.5 mg/day and had a complete remission of nephrotic syndrome with a stable clinical course over 30 years. To our knowledge, our patients have the longest follow-up time without proteinuria.
Aybal Kutlugün
Aysun
A
Department of Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. draysunaybal@yahoo.com
Yildirim
Tolga
T
Altindal
Mahmut
M
Arici
Mustafa
M
Yasavul
Unal
U
Turgan
Cetin
C
D000328:Adult; D000686:Amyloidosis / Q000145:classification / Q000150:complications / Q000209:etiology*; D003078:Colchicine / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000209:etiology; D050257:Tubulin Modulators / Q000627:therapeutic use; D055815:Young Adult
D050257:Tubulin Modulators; D003078:Colchicine