Mass spectrometry and renal calculi.
The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.
Penescu
Mircea
M
"Carol Davila" Hospital of Nephrology, 4 Calea Grivitei Street, RO-010701 Bucharest, Romania.
Purcarea
Victor Lorin
VL
Sisu
Ioana
I
Sisu
Eugen
E
D000818:Animals; D002129:Calcium Oxalate / Q000032:analysis / Q000652:urine; D002853:Chromatography, Liquid / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D005506:Food Contamination / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry* / Q000652:urine; D013058:Mass Spectrometry / Q000379:methods*; D053495:Osteopontin / Q000652:urine; D020543:Proteome / Q000032:analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D053719:Tandem Mass Spectrometry / Q000379:methods; D014227:Triazines / Q000633:toxicity / Q000652:urine
D020543:Proteome; D014227:Triazines; D053495:Osteopontin; D002129:Calcium Oxalate; C011907:melamine