Doing cell biology in embryos: regulated membrane traffic and its implications for cadherin biology.
Regulated trafficking of cadherin adhesion molecules is often invoked as a mechanism to generate dynamic adhesive cell-cell contacts for tissue modeling and morphogenesis. The past 2-3 years have seen several important papers that tackle the cell biology of cadherin trafficking in organismal systems to provide new insights into both mechanism and morphogenetic impact.
Institute for Molecular Bioscience and Division of Molecular Cell Biology, The University of Queensland St Lucia, Brisbane, Queensland 4072 Australia.
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