Prognostic value of sinus CT scans in hematopoietic stem cell transplantation.
Hematopoietic Stem Cell Transplant (HSCT) causes immunosuppression and predisposition to sinusitis. CT scans are complementary exams used in the diagnosis of sinusitis; however, its use in every patient is questionable.


OBJECTIVE
to check the usefulness of ordering a CT scan prior to HSCT and to study the relationship between anatomical variations and sinusitis.


METHODS
prospective study in which we performed paranasal CT scans before and after HSCT, using the Lund and Mackay score.


RESULTS
77.5% and 61% of CT scans showed no evidence of sinus disease before and after HSCT. CT staging was not associated with sinusitis after HSCT. Anatomical variations were related to radiographic disease severity, but not to development of sinusitis after HSCT. There was no relation between pre-CT staging and sinusitis after BMT.


CONCLUSIONS
CT scans are not useful for all patients before HSCT. Anatomical variation is not a predictive feature to sinusitis but it can determine its severity.
medical sciences - otorhinolaryngology at FCM-UNICAMP. erica.ortiz@terra.com.br
Erica
E
Ortiz
Erika
E
Nakamura
Rodrigo
R
Magalhães
Cármino Antonio de
CA
Souza
Carlos Takahiro
CT
Chone
Afonso Celso
AC
Vigorito
Eulalia
E
Sakano
D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010256:Paranasal Sinuses / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D010865:Pilot Projects; D011446:Prospective Studies; D015203:Reproducibility of Results; D012307:Risk Factors; D012852:Sinusitis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed