Terpenoids from the aerial parts of Parasenecio deltophylla.
Five new modified eremophilane-type sesquiterpenes (1-5), including three norsesquiterpenes (1-3), and one new monoterpene (6) were isolated from the aerial parts of Parasenecio deltophylla. Their structures were established on the basis of HRMS and NMR methods. The cytotoxicity of compounds 1-4 and 6 against selected cancer cell lines, including human promyelocytic leukemia (HL-60) and human hepatoma (Hep-G2), was evaluated. Antioxidant activities of these compounds were assessed by ABTS and DPPH methods.
Huang
Guo-Du
GD
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
Yang
Yong-Jin
YJ
Wu
Wang-Suo
WS
Zhu
Ying
Y
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D052160:Benzothiazoles / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013451:Sulfonic Acids / Q000494:pharmacology
C554328:3-O-palmitoylloliolide; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D010851:Picrates; D012717:Sesquiterpenes; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl