Easiness of use and validity testing of VS-SENSE device for detection of abnormal vaginal flora and bacterial vaginosis.
Accessing vaginal pH is fundamental during gynaecological visit for the detection of abnormal vaginal flora (AVF), but use of pH strips may be time-consuming and difficult to interpret. The aim of this study was to evaluate the VS-SENSE test (Common Sense Ltd, Caesarea, Israel) as a tool for the diagnosis of AVF and its correlation with abnormal pH and bacterial vaginosis (BV). The study population consisted of 45 women with vaginal pH ≥ 4.5 and 45 women with normal pH. Vaginal samples were evaluated by VS-SENSE test, microscopy and microbiologic cultures. Comparing with pH strips results, VS-SENSE test specificity was 97.8% and sensitivity of 91%. All severe cases of BV and aerobic vaginitis (AV) were detected by the test. Only one case with normal pH had an unclear result. Concluding, VS-SENSE test is easy to perform, and it correlates with increased pH, AVF, and the severe cases of BV and AV.
Femicare Clinical Research for Women, Lombardstraat 28, 3300 Tienen, Belgium. gilbert.donders@femicare.net
Gilbert G G
GG
Donders
Camila
C
Marconi
Gert
G
Bellen
D000328:Adult; D001391:Azo Compounds; D001419:Bacteria / Q000302:isolation & purification; D001431:Bacteriological Techniques / Q000379:methods*; D016009:Chi-Square Distribution; D003116:Color; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008853:Microscopy; D008875:Middle Aged; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D014621:Vagina / Q000382:microbiology*; D016585:Vaginosis, Bacterial / Q000175:diagnosis*
D001391:Azo Compounds; C013617:nitrazine yellow