Timing of cochlear responses inferred from frequency-threshold tuning curves of auditory-nerve fibers.
Links between frequency tuning and timing were explored in the responses to sound of auditory-nerve fibers. Synthetic transfer functions were constructed by combining filter functions, derived via minimum-phase computations from average frequency-threshold tuning curves of chinchilla auditory-nerve fibers with high spontaneous activity (Temchin et al., 2008), and signal-front delays specified by the latencies of basilar-membrane and auditory-nerve fiber responses to intense clicks (Temchin et al., 2005). The transfer functions predict several features of the phase-frequency curves of cochlear responses to tones, including their shape transitions in the regions with characteristic frequencies of 1 kHz and 3-4 kHz (Temchin and Ruggero, 2010). The transfer functions also predict the shapes of cochlear impulse responses, including the polarities of their frequency sweeps and their transition at characteristic frequencies around 1 kHz. Predictions are especially accurate for characteristic frequencies <1 kHz.
Temchin
Andrei N
AN
Hugh Knowles Center (Dept. of Communication Sciences and Disorders), Northwestern University, 2240 Campus Drive, Evanston, IL 60208-3550, United States.
Recio-Spinoso
Alberto
A
Ruggero
Mario A
MA
D000161:Acoustic Stimulation; D000818:Animals; D001306:Auditory Pathways / Q000502:physiology*; D001309:Auditory Threshold; D001489:Basilar Membrane / Q000294:innervation; D002682:Chinchilla; D003051:Cochlea / Q000294:innervation*; D003056:Cochlear Nerve / Q000502:physiology*; D003198:Computer Simulation; D040542:Mechanotransduction, Cellular; D008959:Models, Neurological; D011930:Reaction Time; D013997:Time Factors