[Effect of chronoexercise on circadian expression of clock genes].
OBJECTIVE
To investigate the molecular biological mechanism of chronoexercise regulating circadian.


METHODS
Expressions of mPer1 and mPer2 in the diencephalon of golden hamster were determined 2 hours after acute exhaustive exercise (circadian time 6) by quantitative RT-PCR.


RESULTS
Chronoexercise at CT6 significantly decreased expressions of mPer1 and mPer2 in the diencephalon of golden hamster.


CONCLUSIONS
Inhibitory effect of chronoexercise on Per1 and Per2 mRNA levels in the diencephalon of golden hamster at CT6 may be achieved transcription-translation-based autoregulatory negative feedback loop.
Jian
Kun-lin
KL
PLA Institute of Physical Education, Guangzhou 510502, China. jianman00006@yahoo.com
Xu
Ying
Y
Wang
Xiang-qian
XQ
Ai
Dong-sheng
DS
Liu
Li
L
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D006224:Cricetinae; D015870:Gene Expression; D056950:Period Circadian Proteins / Q000235:genetics / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
D056950:Period Circadian Proteins; D012333:RNA, Messenger