Periodic fever syndrome and autoinflammatory diseases.
The concept of autoinflammatory disease as a new disease classification has resulted in a paradigm shift in our understanding of the the broad spectrum of immunological diseases. The effectiveness of interleukin-1 blockade in a variety of disorders has resulted in a marked reduction in suffering for many of these patients.
Dickie
Laura J
LJ
NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St. James's University Hospital Leeds, LS9 7TF UK.
Savic
Sinisa
S
Aziz
Azad
A
Sprakes
Michael
M
McDermott
Michael F
MF