New marker for paracetamol poisoning-revolution or evolution?
There is a pressing need for new biomarkers that can improve the care of patients with paracetamol poisoning, a common clinical problem. In this issue of Clinical Toxicology a new marker is proposed that has a number of attractive properties. This commentary discusses the use of biomarkers in the context of the management of paracetamol-induced liver injury. New biomarkers should allow better triage and management of & "at risk" patients.
NPIS Edinburgh, Scottish Poisons Information Bureau, Royal Infirmary of Edinburgh, Edinburgh, UK. james.dear@ed.ac.uk
James W
JW
Dear
D000082:Acetaminophen / Q000506:poisoning*; D000410:Alanine Transaminase / Q000097:blood*; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D015415:Biomarkers; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis; D006801:Humans
D018712:Analgesics, Non-Narcotic; D015415:Biomarkers; D000082:Acetaminophen; D000410:Alanine Transaminase