Two new alkaloids from Narcissus serotinus L.
The Amaryllidaceae family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus L. is a plant belonging to this family and its geographical distribution is mainly located along the Mediterranean coast. In the present work, specimens collected near Casablanca (Morocco) were used to study the alkaloid content of this species. Starting with 350 g of the whole plant we used standard extraction and purification procedures to obtain fractions and compounds for GC-MS and NMR analysis. As well as five known alkaloids, we isolated two new compounds: 1-O-(3´-acetoxybutanoyl)lycorine and narseronine. The latter has been previously published, but with an erroneous structure.
Pigni
Natalia B
NB
Department of Natural Products, Plant Biology and Soil Science, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Berkov
Strahil
S
Elamrani
Abdelaziz
A
Benaissa
Mohammed
M
Viladomat
Francesc
F
Codina
Carles
C
Bastida
Jaume
J
D000470:Alkaloids / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D009018:Morocco; D031427:Narcissus / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry
D000470:Alkaloids; D010936:Plant Extracts