Evolution of chronic hypertensive nephropathies treated with ACE inhibitors on patients in pre-dialysis stage.
Arterial hypertension (HT), being the main factor of negative evolution for chronic nephropathies, has imposed a careful adjustment of pharmacological treatment. The widespread use of angiotensin conversion enzyme inhibitors (ACE inhibitors) has brought into attention the side effects of this class of antihypertensive drugs. The study focuses on the clinical and paraclinical evaluation of these elements, by means of detecting variations in serum creatinine, natriuresis and diuresis levels factors. In addition, cardiac cavity measurements have been made and the results have lead to the conclusion that the decision to administer ACE inhibitors has to be well founded, and patients should be closely monitored in order to prevent complications of the primary disease.
Costea
Andreea-Cristina
AC
Nephrology Clinic, "Sf. Loan" Hospital, Bucharest, Romania. acostea100@yahoo.com7
Costea
D O
DO
David
Cristiana
C
Grasa
C N
CN
D000328:Adult; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D003404:Creatinine / Q000652:urine; D004231:Diuresis / Q000187:drug effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009318:Natriuresis / Q000187:drug effects; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy
D000806:Angiotensin-Converting Enzyme Inhibitors; D003404:Creatinine