[Improved weighted cross-correlation coefficient with a new kernel and its application in predicting T cell epitopes].
We designed a weighted cross-correlation coefficient considering the "anchor" of the T cell epitopes, and used an evolutionary algorithm to search for an optimal weight vector. A SVM model with this new peptide similarity kernel was evaluated on a T-cell data set. The results demonstrated a good performance of this method.
School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China. hjing@fimmu.com
Jing
J
Huang
Jian-hua
JH
Ma
Nan
N
Liu
Shan-shan
SS
Qian
D000465:Algorithms; D001185:Artificial Intelligence; D018984:Epitopes, T-Lymphocyte; D015233:Models, Statistical; D010455:Peptides
D018984:Epitopes, T-Lymphocyte; D010455:Peptides