Cells in tight spaces: the role of cell shape in cell function.
In this issue, Pitaval et al. (2010. J. Cell Biol. doi:10.1083/jcb.201004003) demonstrate that cell geometry can regulate the elaboration of a primary cilium. Their findings and approaches are part of a historical line of inquiry investigating the role of cell shape in intracellular organization and cellular function.
Department of Systems Biology, Harvard Medical School, and 2 Renal Division, Brigham and Women's Hospital, Boston, MA 02115, USA. Jagesh_Shah@hms.harvard.edu
Jagesh V
JV
Shah
D002455:Cell Division / Q000502:physiology; D016764:Cell Polarity; D048430:Cell Shape; D002923:Cilia / Q000502:physiology / Q000648:ultrastructure*; D003593:Cytoplasm / Q000502:physiology / Q000648:ultrastructure; D008941:Spindle Apparatus / Q000502:physiology / Q000648:ultrastructure