Self-reported and objectively measured activity related to biomarkers using NHANES.
OBJECTIVE
The purpose of this study was to examine the independent associations of self-reported and objectively measured (using accelerometers) moderate to vigorous physical activity (MVPA) with physiological and anthropometric biomarkers in a nationally representative sample of U.S. adults.


METHODS
Data from the cross-sectional National Health and Nutrition Examination Survey 2003-2006 data were analyzed. Adults 20 yr and older (N=5797) with self-reported PA and 4 d or more of accelerometer data were included in the analyses. Pregnant or lactating women were excluded. Outcomes were blood pressure, body mass index, waist circumference, triceps and subscapular skinfolds, cholesterol, triglyceride, C-reactive protein, homocysteine, and insulin resistance and hyperinsulinemia indices.


RESULTS
Objectively measured MVPA displayed stronger independent associations with the biomarkers than did self-reported MVPA, even after adjusting for sociodemographic and health factors (adjusted Wald F values=3.9-85.6, P<0.05-0.0001). Self-reported and objectively measured MVPA were independently associated with skinfold measures, HDL, and C-reactive protein when both were included in the model.


CONCLUSIONS
Objectively measured MVPA displayed stronger associations with physiological and anthropometric biomarkers than self-reported MVPA. However, self-reported and objectively measured MVPA appear to capture distinct aspects of PA that are independently associated with certain biomarkers. Further understanding of the distinct contributions of self-reported and objectively measured PA to health outcomes could help to better identify optimal activity level and pattern.
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892-7335, USA. atienzaa@mail.nih.gov
Audie A
AA
Atienza
Richard P
RP
Moser
Frank
F
Perna
Kevin
K
Dodd
Rachel
R
Ballard-Barbash
Richard P
RP
Troiano
David
D
Berrigan
D056044:Actigraphy / Q000295:instrumentation; D000328:Adult; D015415:Biomarkers; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D009749:Nutrition Surveys; D012044:Regression Analysis; D057566:Self Report; D014481:United States; D055815:Young Adult
D015415:Biomarkers