Advances in systolic heart failure.
Heart failure due to systolic dysfunction has enormous global impact. Medical management based on an understanding of the pathophysiology of the disease as well as its neurohormonal mechanisms has greatly advanced over the past 25 years. Below is a review of recent and emerging data on epidemiology and diagnosis of heart failure due to systolic dysfunction and the current and future management techniques to ameliorate this disease. At the end, we will highlight three significant trials in the field in 2009 that will impact heart failure care: STICH, MADIT-CRT, and HeartMate II.
Yuzefpolskaya
Melana
M
Division of Cardiology, Department of Medicine, St Luke's Roosevelt Hospital, Columbia University College of Physicians and Surgeons 425, 425 West 59 Street, New York, NY 10019 USA.
Weinberg
Catherine
C
Kukin
Marrick
M