Cobalt-catalyzed intramolecular C-N and C-O cross-coupling reactions: synthesis of benzimidazoles and benzoxazoles.
Cobalt(ii)-complex catalyzes efficiently the intramolecular C-N and C-O cross-couplings of Z-N'-(2-halophenyl)-N-phenylamidines and N-(2-bromophenyl)benzamides to afford the corresponding substituted benzimidazoles and benzoxazoles in the presence of K(2)CO(3) at moderate temperature. The protocol is general, air stable and affords the products selectively in moderate to high yield.
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, India.
Prasenjit
P
Saha
Md Ashif
MA
Ali
Pokhraj
P
Ghosh
Tharmalingam
T
Punniyamurthy