Selective internuclear coupling estimation in the solid-state NMR of multiple-spin systems.
A new solid-state NMR method is presented for estimating homonuclear dipole-dipole couplings for selected groups of nuclear spins in a multiple-spin coupled network. The methodology combines off-magic-angle spinning, frequency selective spin echoes, and multiple quantum filtering. The new method is insensitive to incoherent relaxation effects and may be used to estimate weak couplings. Internuclear (13)C-(13)C couplings are estimated in uniformly (13)C-labelled l-Histidine·HCl·H(2)O. Weak intermolecular couplings between (13)C nuclei separated by distances exceeding 6 Å are estimated.
School of Chemistry, University of Southampton, SO171BJ, UK.
Pierre
P
Thureau
Andrea C
AC
Sauerwein
Maria
M
Concistrè
Malcolm H
MH
Levitt
D002247:Carbon Isotopes; D006639:Histidine / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D012015:Reference Standards
D002247:Carbon Isotopes; D006639:Histidine