Mitral valve growth after posterior annular stabilization with untreated autologous pericardial strip in children with mitral valve insufficiency.
BACKGROUND
Mitral valve (MV) reconstruction is the technique of choice for MV disease in infants and children. We evaluated whether our technique of posterior annulus stabilization with untreated autologous pericardial strip allows growth of anterior MV leaflet and its annulus.


METHODS
Seventeen children (mean age, 9.43 ± 6.03 years; range, 1 to 17) were prospectively followed up after MV repair for mitral insufficiency with severe annular dilation and anterior mitral leaflet prolapse. The MV repair techniques were Paneth posterior annuloplasty (n = 14) and Gerbode plication plasty (n = 3), both modified with pericardial strip stabilization of the posterior annulus (Hetzer's modification). Echocardiograms were taken perioperatively and serially during follow-up.


RESULTS
Serial Doppler echocardiography showed good valve function at mean follow-up of 13.62 ± 2.37 years. Left ventricular function was significantly improved, and mitral insufficiency was either absent or significantly decreased. Diameter of anterior MV leaflet and its annulus increased linearly in relation to body size. These findings were consistent in all patients except 3 who required reoperation 1 and 2 years postoperatively, respectively, for recurrent and progressive insufficiency. On reoperation, the pericardial strip was perfectly attached to the posterior annulus and covered by a fibrous tissues without calcification.


CONCLUSIONS
Stabilization of the posterior annulus with pericardial strip prevents further posterior annular dilation and allows anterior MV leaflet and its annulus to grow in relation to body size over time, as well as preserving flexible properties of the MV orifice.
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany. delmo-walter@dhzb.de
Eva Maria
EM
Delmo Walter
Henryk
H
Siniawski
Stanislav
S
Ovroutski
Roland
R
Hetzer
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008943:Mitral Valve / Q000473:pathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000503:physiopathology / Q000601:surgery*; D010496:Pericardium / Q000601:surgery*; D011446:Prospective Studies; D016277:Ventricular Function, Left