Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease.
Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of the pulmonary symptoms along with improvement of anthropometric parameters and hemoglobin over a short-term follow-up period of 8-17 months. Inhaled/oral steroids and immunosuppressants could be weaned off after dietary exclusion therapy in each of the three children. Gluten free diet should be instituted in all patients diagnosed with Lane-Hamilton syndrome. It ameliorates both the pulmonary as well as the intestinal symptoms although the precise mechanism of the pulmonary response is as yet unclear.
Department of Pediatrics, Lok Nayak Hospital, New Delhi, India.
Gulshan R
GR
Sethi
Kamal K
KK
Singhal
Amarender S
AS
Puri
Mukta
M
Mantan
D000293:Adolescent; D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy*; D002648:Child; D055050:Diet, Gluten-Free; D005260:Female; D006486:Hemosiderosis / Q000150:complications* / Q000178:diet therapy*; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000178:diet therapy*; D008297:Male; D000097545:Hemosiderosis, Pulmonary