Endogenous gastric mediators: patho-physiological role and measurements.
The protocols described in this unit are designed to present the major endogenous gastric mediators involved in the control of gastric acid secretion, namely gastrin and histamine, and in the regulation of gastric motility, which include motilin and ghrelin, under physiological and pathological conditions. The measurement of these mediators in plasma or serum of humans and animals by radioimmunoassay are described and their pathophysiological role is discussed.
Konturek
Stanislaw J
SJ
Jagiellonian University, Cracow, Poland.
Bielanski
Wladysław
W
Konturek
Peter C
PC
Brzozowski
Thomas
T
D000818:Animals; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism* / Q000503:physiopathology*; D005755:Gastrins / Q000097:blood* / Q000502:physiology*; D054439:Ghrelin / Q000097:blood; D006632:Histamine / Q000097:blood* / Q000502:physiology*; D006801:Humans; D009037:Motilin / Q000097:blood; D011863:Radioimmunoassay / Q000379:methods; D014116:Toxicology / Q000379:methods
D005755:Gastrins; D054439:Ghrelin; D009037:Motilin; D006632:Histamine