Cutting the Gordian knot: the blockage of the jejunal tube, a rare complication of Duodopa infusion treatment.
We present the case of a 21-year-old man with advanced refractory Parkinson's disease treated with Duodopa continuous infusion. With this therapy, the patient had a spectacular recovery but after six months, he experienced an aggravation of his symptoms. A failure of his pumping system was suspected but we discovered that the jejunal tube was blocked due to a knot around a bezoar. This is the first complication of this kind described with the Duodopa infusion technique.
Gastroenterology Department, University Emergency Hospital, "Carol Davila" University of Medicine and Pharmacy Bucharest, 169 Splaiul Independentei Street, District 5, Bucharest, Romania. negreanu_99@yahoo.com
Lucian M
LM
Negreanu
Negreanu M
NM
Lucian
Bogdan Ovidiu
BO
Popescu
Popescu Bogdan
PB
Ovidiu
Ruxandra Doina
RD
Babiuc
Babiuc Ruxandra
BR
Doina
Amalia
A
Ene
Ene
E
Amalia
Dan
D
Andronescu
Andronescu
A
Dan
Ovidiu Alexandru
OA
Băjenaru
Băjenaru Ovidiu
BO
Alexandru
D000978:Antiparkinson Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D001630:Bezoars / Q000209:etiology* / Q000473:pathology; D002230:Carbidopa / Q000008:administration & dosage* / Q000009:adverse effects*; D004338:Drug Combinations; D005774:Gastrostomy; D006801:Humans; D007260:Infusion Pumps / Q000009:adverse effects; D007583:Jejunum; D007980:Levodopa / Q000008:administration & dosage* / Q000009:adverse effects*; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy*; D055815:Young Adult
D000978:Antiparkinson Agents; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa