SEOM clinical guidelines for the treatment of advanced colorectal cancer.
Colorectal cancer is the first cause of cancer diagnosis in Spain. Over half of the patients are diagnosed with or will eventually develop distant metastasis. The current manuscript aims to provide synthetic practical guidelines for the therapeutic approaches in advanced disease. Available systemic therapeutic options, and integration and sequencing of chemotherapy with surgical procedures are discussed. Extent of disease, treatment objective, tumor kras mutation status, as well as patient's functional and comorbid conditions shall be considered to properly design the most adequate therapeutic strategy.
García-Carbonero
Rocío
R
Oncology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.
Gómez España
M Auxiliadora
MA
Casado Sáenz
Enrique
E
Alonso Orduña
Vicente
V
Cervantes Ruipérez
Andrés
A
Gallego Plazas
Javier
J
García Alfonso
Pilar
P
Juez Martel
Ignacio
I
González Flores
Encarnación
E
Lomas Garrido
María
M
Isla Casado
Dolores
D
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