[Association between penoscopy data and urethral cytology among men with partners who had cervical lesions associated with human papilloma virus].
OBJECTIVE
The aim of this study was to identify human papillomavirus lesions in a group of men whose sexual partners had cervical intraepithelial lesions associated with low-grade HPV confirmed by PCR-DNA. We carried out a correlation between urethral cytology penoscopy data and PCR-DNA results.


METHODS
We studied 100 male volunteers with an age range of 21-45 (median 30 years) and divided them into two groups according to the identified virus; two groups were conformed, a high risk and a low risk virus.


RESULTS
For the penoscopy data we included the following: type of hirsutoide papillomatosis in 40 (40%) cases, common warts in 24 (24%) cases, papillomatosis in plaque in 6 (6%) and 47% displayed an urethra with a foamy appearance. In urethral cytology we did not find evidence of koilocytes in 58% and 42% showed no koilocytes. Inflammation was observed in 44 cases; an added infection was noted among 60 cases. Depending on the type of infection we found non-specific bacteria in 8%, bacillary in 10%, mixed infection in 12%, changes suggestive of Gardnerella vs 24%, and Chlamydia treatment in 6%. Dyskeratosis was noted in 47% of study participants. 67 patients were treated with imiquimod cream 5% and 33% received non-specific treatment. Regarding improvement we noted that 67 (67%) cases showed 46/67 hypochromic stains after treatment with imiquimod. Disappearance of the lesions in the penis were observed among 65 cases and only 35 remained with lesions. Regarding high-risk HPV we found a significant difference in odor (p = .004, phi = .004), urethral discharge (p = .007), pearly papules in raphe (p = .023), with inflammation, dyskeratosis and added infection (p = .000 respectively). We also noted hypochromic spots or skin discoloration after treatment with imiquimod among 5% of subjects (p = .046).


CONCLUSIONS
In our study we observed that high-risk HPV is associated with increased penile lesions and frank evidence of koilocytes in urethral cytology. We recommend that sexual partners of women with cervical lesions associated with HPV complete a control study with penoscopy data and urethral cytology, since most have concurrent infections and lesions that can treated in early stages.
Servicio de Ginecoobstetricia, Secretaría de Salud del Estado de Guerrero, México.
América
A
Alarcón-Herrera
Abraham
A
Cervantes-Sánchez
Teresa
T
Meneses-Miranda
Manuel
M
Castillejos-López
Horacio
H
Astudillo-de la Vega
Martha Lilia
ML
Tena-Suck
D000328:Adult; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections; D010413:Penis / Q000473:pathology*; D012189:Retrospective Studies; D014521:Urethra / Q000473:pathology*; D002583:Uterine Cervical Neoplasms; D055815:Young Adult