Field defects in DNA repair: is loss of MGMT an initial event in colorectal carcinogenesis?
Graham
Trevor A
TA
Cancer Research UK London Research Institute, London WC2A 3PX, UK. trevor.graham@cancer.org.uk
Leedham
Simon J
SJ
D002471:Cell Transformation, Neoplastic / Q000235:genetics* / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000201:enzymology / Q000235:genetics*; D015254:DNA Modification Methylases / Q000172:deficiency / Q000235:genetics*; D004260:DNA Repair; D045643:DNA Repair Enzymes / Q000172:deficiency / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics; D006801:Humans; D025521:Tumor Suppressor Proteins / Q000172:deficiency / Q000235:genetics*
D004273:DNA, Neoplasm; D025521:Tumor Suppressor Proteins; D015254:DNA Modification Methylases; C515491:MGMT protein, human; D045643:DNA Repair Enzymes