Profile of patients with hypertension included in a cohort with HIV/AIDS in the state of Pernambuco, Brazil.
BACKGROUND
Hypertension (HBP) is modifiable risk factor, whose control may reduce cardiovascular disease in patients with human immunodeficiency virus (HIV).


OBJECTIVE
To estimate the prevalence of hypertension and describe the characteristics of patients with hypertension infected by HIV/AIDS.


METHODS
A cross-sectional study aligned to a cohort of patients with HIV/AIDS. The study considered hypertension at levels > 140/90 mmHg or use of antihypertensive drugs and pre-hypertension at levels > 120/80 mmHg.


RESULTS
Out of 958 patients, 388 (40.5%) were normotensive, 325 (33.9%) were pre-hypertensive, and 245 (25.6%) were hypertensive. Out of these 245 patients, 172 (70.2%) were aware of the fact there they were hypertensive, and 36 (14.8%) had blood pressure controlled. Sixty-two (62) patients (54.4%) were diagnosed with hypertension after HIV diagnosis. Lipodystrophy occurred in 95 (46.1%) patients; overweight/obesity in 129 (52.7%). Use of antiretrovirals occurred in 184 (85.9%), 89 (41.6%) with protease inhibitors (PI) and 95 (44.4%) without PI. Out of these patients, 74.7 used antivirals > 24 months. Age, family history of hypertension, waist circumference, body mass index and triglyceride levels were higher among hypertensive patients. Time of HIV infection, CD4 count, viral load, time and type of antiretroviral regimen were similar in hypertensive and prehypertensive patients.


CONCLUSIONS
The high frequency of uncontrolled hypertensive patients and cardiovascular risks in HIV-infected patients point out to the need for preventive and therapeutic measures against hypertension in this group.
Universidade Federal da Paraíba, João Pessoa, Brazil.
Evanizio Roque de
ER
Arruda Júnior
Heloisa Ramos
HR
Lacerda
Líbia Cristina Rocha Vilela
LC
Moura
Maria de Fátima Pessoa Militão de
Mde F
Albuquerque
Demócrito de Barros
Dde B
Miranda Filho
George Tadeu Nunes
GT
Diniz
Valéria Maria Gonçalves de
VM
Albuquerque
Josefina Cláudia Zirpoli
JC
Amaral
Verônica Soares
VS
Monteiro
Ricardo Alencar de Arraes
RA
Ximenes
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000453:epidemiology*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D016009:Chi-Square Distribution; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000145:classification / Q000453:epidemiology*; D008019:Life Style; D008060:Lipodystrophy / Q000453:epidemiology; D008297:Male; D009765:Obesity / Q000453:epidemiology; D012016:Reference Values; D012307:Risk Factors
D019380:Anti-HIV Agents