Bioinformatic detection of horizontally transferred DNA in bacterial genomes.
We highlight a selection of recent research on computational methods and associated challenges surrounding the prediction of bacterial horizontal gene transfer. This research area continues to face controversy, but is becoming more critical as the importance of horizontal gene transfer in medically and ecologically important prokaryotic evolution is further appreciated.
Langille
Morgan G I
MG
Department of Molecular Biology and Biochemistry, Simon Fraser University Burnaby, BC Canada V5A 1S6.
Brinkman
Fiona S L
FS