Outcome of congenital diaphragmatic hernia repair depending on patch type.
BACKGROUND
Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials.


METHODS
A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009.


RESULTS
Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17% and was associated with a 50% recurrence rate and 67% re-recurrence rate. SIS was associated with 19% incidence of SBO, a recurrence rate of 22% and a 50% re-recurrence rate, whereas AlloDerm had a 40% incidence of SBO, 40% recurrence rate, and 100% re-recurrence rate.


CONCLUSIONS
As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.
Children's Mercy Hospital and Clinics, Pediatric Surgery, Kansas City, MO64108, USA.
C A
CA
Laituri
C L
CL
Garey
P A
PA
Valusek
F B
FB
Fike
B F
BF
Fike
A J
AJ
Kaye
D J
DJ
Ostlie
C L
CL
Snyder
S D
SD
St Peter
D003964:Diaphragm / Q000601:surgery*; D006548:Hernia, Diaphragmatic / Q000601:surgery; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D019919:Prosthesis Implantation / Q000009:adverse effects; D012189:Retrospective Studies; D013526:Surgical Mesh / Q000009:adverse effects; D016896:Treatment Outcome