Molecular analysis of 2 cases of methicillin-resistant Staphylococcus aureus cholecystitis and a review of the literature.
We present 2 cases of methicillin-resistant Staphylococcus aureus (MRSA) acalculous cholecystitis and review the literature. We performed pulsed field gel electrophoresis, typing of the staphylococcal cassette chromosome mec element, and Panton-Valentine leukocidin testing on the isolates. One each was closely related to USA100 and USA300, indicating that both healthcare- and community-associated strains may cause MRSA cholecystitis.
Division of Infectious Diseases, St. John Hospital and Medical Center, Detroit, MI 48236, USA.
Madhuri
M
Segireddy
Kathleen
K
Riederer
Leonard B
LB
Johnson
D000369:Aged, 80 and over; D001427:Bacterial Toxins / Q000235:genetics; D015373:Bacterial Typing Techniques; D002764:Cholecystitis / Q000382:microbiology* / Q000473:pathology*; D017714:Community-Acquired Infections / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005098:Exotoxins / Q000235:genetics; D006801:Humans; D007956:Leukocidins / Q000235:genetics; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*
D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin