Small-for-size syndrome in adult-to-adult living-related liver transplantation.
Small-for-size syndrome (SFSS) in adult-to-adult living-related donor liver transplantation (LRLT) remains the greatest limiting factor for the expansion of segmental liver transplantation from either cadaveric or living donors. Portal hyperperfusion, venous pathology, and the arterial buffer response significantly contribute to clinical and histopathological manifestations of SFSS. Here, we review the technical aspects of surgical and radiological procedures developed to treat SFSS in LRLT, along with the pathophysiology of this condition.
Salvatore
S
Gruttadauria
Duilio
D
Pagano
Angelo
A
Luca
Bruno
B
Gridelli
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D004621:Embolization, Therapeutic; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D008099:Liver / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D016031:Liver Transplantation / Q000000981:diagnostic imaging / Q000379:methods*; D019520:Living Donors; D009929:Organ Size; D011859:Radiography
D000319:Adrenergic beta-Antagonists