The European Nucleotide Archive.
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is Europe's primary nucleotide-sequence repository. The ENA consists of three main databases: the Sequence Read Archive (SRA), the Trace Archive and EMBL-Bank. The objective of ENA is to support and promote the use of nucleotide sequencing as an experimental research platform by providing data submission, archive, search and download services. In this article, we outline these services and describe major changes and improvements introduced during 2010. These include extended EMBL-Bank and SRA-data submission services, extended ENA Browser functionality, support for submitting data to the European Genome-phenome Archive (EGA) through SRA, and the launch of a new sequence similarity search service.
Leinonen
Rasko
R
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. rasko@ebi.ac.uk
Akhtar
Ruth
R
Birney
Ewan
E
Bower
Lawrence
L
Cerdeno-Tárraga
Ana
A
Cheng
Ying
Y
Cleland
Iain
I
Faruque
Nadeem
N
Goodgame
Neil
N
Gibson
Richard
R
Hoad
Gemma
G
Jang
Mikyung
M
Pakseresht
Nima
N
Plaister
Sheila
S
Radhakrishnan
Rajesh
R
Reddy
Kethi
K
Sobhany
Siamak
S
Ten Hoopen
Petra
P
Vaughan
Robert
R
Zalunin
Vadim
V
Cochrane
Guy
G
D001483:Base Sequence; D030561:Databases, Nucleic Acid; D005060:Europe; D059014:High-Throughput Nucleotide Sequencing; D058977:Molecular Sequence Annotation