Is laparoscopic resection the appropriate management of a jejunal gastrointestinal stromal tumor (GIST)? Report of a case.
A 51-year-old female patient presented with iron deficiency anemia. Upper and lower gastrointestinal endoscopy were unremarkable. Computed tomography enteroclysis showed an ovoid 3×4-cm jejunal tumor with intraluminal protrusion and exophytic growth pattern, without lymphadenopathy or metastatic disease. Laparoscopic resection of the tumor was successfully carried out. Histologically, a mesenchymal tumor composed of spindle cells with an interlacing bundle pattern and high-mitotic activity greater than 10 mitoses/50 high-power fields were observed. The immunohistochemistry showed that the tumor was KIT (CD117)-, vimentin-, smooth muscle actin-, and S-100-positive, whereas it was CD34-negative. These findings were consistent with the features of a gastrointestinal stromal tumor. The patient had an uneventful postoperative course, and after 10 months of follow-up, she is well without any evidence of tumor recurrence.
2nd Department of Surgery, Democritus University of Thrace, University General Hospital of Alexanroupolis, Dragana Alexandroupolis, Greece.
Michail
M
Pitiakoudis
Petros
P
Zezos
Nikos
N
Courcoutsakis
Nikolaos
N
Papanas
Alexandra
A
Giatromanolaki
Efthimios
E
Sivridis
Georgios
G
Kouklakis
Constantinos
C
Simopoulos
D018798:Anemia, Iron-Deficiency / Q000209:etiology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000601:surgery*; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications / Q000601:surgery*; D010535:Laparoscopy; D008875:Middle Aged