Optical coherence tomography/scanning laser ophthalmoscopy imaging of optic nerve head drusen.
OBJECTIVE
To evaluate optical coherence tomography/scanning laser ophthalmoscopy (OCT/SLO) imaging for optic nerve head drusen (ONHD).


METHODS
Nine consecutive eyes with ONHD were imaged. Each underwent visual field testing, 20-MHz B-scan ultrasonography, photography, and OCT/SLO imaging of the nerve head. Similar evaluation was performed on 12 matched, disease-free control eyes for comparison.


RESULTS
OCT/SLO imaging of ONHD demonstrated lucencies (100%), variable amounts of displacement, and thickening of the overlying nerve fiber layer, as well as disorganization of the adjacent retinal pigment epithelium (44%). Optic nerve head topography was measured (using horizontal and vertical electronic calipers). Mean disc diameter was 1.81 mm (range: 1.49 to 2.12 mm). All ONHD demonstrated anterior displacement of the base of the optic nerve cup (shallowing) compared to controls. The cup base was a mean +0.32 mm anterior to the retinal pigment epithelium for ONHD versus -0.23 mm for normal controls.


CONCLUSIONS
OCT/SLO revealed unique and clinically helpful views of ONHD.
The New York Eye Cancer Center, New York, NY, USA.
Nandesh N
NN
Patel
Julia P
JP
Shulman
Kimberly J
KJ
Chin
Paul T
PT
Finger
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods*; D009898:Optic Disk / Q000473:pathology*; D015594:Optic Disk Drusen / Q000175:diagnosis*; D041623:Tomography, Optical Coherence