Lyotropic liquid crystalline phases from helical β-peptides as alignment media.
Lyotropic liquid crystalline (LLC) phases from helical β-peptides are proposed as novel water-based alignment media. In contrast to α-peptides, β-peptides form LLCs at very short chain lengths and at concentrations as low as 1 percent. Spectra obtained in these LLC phases are artefact-free and lead to RDCs of the desired size. First indications towards enantiodiscrimination are provided.
Clemens Schöpf Institut für Organische Chemie und Biochemie, Technische Universität Darmstadt, Petersenstr. 22, 64287 Darmstadt, Germany. cthiele@thielelab.de
Christina M
CM
Thiele
William C
WC
Pomerantz
Nicholas L
NL
Abbott
Samuel H
SH
Gellman
D050866:Liquid Crystals / Q000737:chemistry*; D008968:Molecular Conformation; D010455:Peptides / Q000737:chemistry*
D010455:Peptides