[Diagnosis and treatment of esthesioneuroblastoma in the nasal cavity and sinuses].
OBJECTIVE
To discuss the clinical characteristics, diagnosis and treatment of esthesioneuroblastoma (ENB).


METHODS
The clinical data of 7 patients with ENB were analyzed retrospectively, and the clinical characteristics, diagnosis, surgical approaches and prognosis of the disease were discussed.


RESULTS
The 7 patients received surgical treatment combined with radiotherapy and chemotherapy. Tumor relapse occurred within one year in two cases, which were treated with a second operation combined with radiotherapy, and one patient died and one survived with tumor after a one-year follow-up.


CONCLUSIONS
Early diagnosis of ENB can be difficult. Transnasal-frontal approach with nasal endoscope is effective approach to ENB treatment, and the patients may benefit from postoperative radiotherapy and chemotherapy to improve the prognosis.
Department of Otorhinolaryngology-Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Chao
C
Cheng
Xiao bin
Xb
Long
D000328:Adult; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000175:diagnosis / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000628:therapy; D012189:Retrospective Studies; D055815:Young Adult