Measurement of disposition half-life, clearance, and residence times.
This unit provides an overview of the principles underlying the elimination process. Experimental design issues, methods of data analysis, and complications that may be encountered are discussed. A complete worked example is provided to exemplify the methods of analysis that are available.
Mayersohn
M
M
The University of Arizona, Tucson, Arizona, USA.
D000818:Animals; D006207:Half-Life; D006801:Humans; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000097:blood / Q000378:metabolism*; D010599:Pharmacokinetics; D012107:Research Design; D013997:Time Factors; D014018:Tissue Distribution; D014116:Toxicology / Q000295:instrumentation / Q000379:methods*
D004364:Pharmaceutical Preparations