One-year follow-up of relapse to risky behaviors and incidence of syphilis among patients enrolled in the HIV case management program.
A longitudinal prospective study was conducted at an AIDS designated hospital in Taiwan. The study aimed to determine the incidence of syphilis and to identify risk factors predicting new onset syphilis and relapse into risky behaviors among 117 patients enrolled in the HIV case management program for 1 year. Having a new episode of syphilis was defined as patients had a fourfold increase of serum rapid plasma reagin titers from baseline to 12-month follow-up. After enrollment, 17% relapsed in unprotected sexual intercourse. New onset syphilis was noted in ten (10.4%) participants, and all were men having sex with men. The incidence of syphilis was 5.8 per 100 person-years. Predictors of a new episode of syphilis were higher CD4 cell counts [hazard ratio (HR), 1.003; 95% confidence interval (CI), 1.00-1.006], and recreational drug use (HR, 18.89; 95% CI, 2.78-128.15). Regular screening for syphilis among patients retaining in HIV care remains necessary.
Department of Nursing, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Nai-Ying
NY
Ko
Hsiao-Ying
HY
Liu
Hsin-Chun
HC
Lee
Yi-Yin
YY
Lai
Chia-Ming
CM
Chang
Nan-Yao
NY
Lee
Po-Lin
PL
Chen
Chi-Jung
CJ
Wu
Wen-Chien
WC
Ko
D000328:Adult; D000368:Aged; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D012309:Risk-Taking; D012747:Sexual Partners; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013587:Syphilis / Q000453:epidemiology*; D013624:Taiwan / Q000453:epidemiology; D047568:Unsafe Sex / Q000706:statistics & numerical data*; D055815:Young Adult