Vitrectomy for vitreous opacities and macular pucker in Gaucher disease.
OBJECTIVE
To report significant surgical results in an uncommon ophthalmologic complication of a rare disease.


METHODS
Interventional case report.


RESULTS
A 16-year-old girl with type III Gaucher disease experienced visual loss in both eyes. Ophthalmologic examination revealed dense whitish vitreous opacities and macular pucker OU. Visual acuity (VA) OD was 20/63 and OS was 20/25. She underwent 25-gauge vitrectomy with removal of the vitreous core, posterior vitreous cortex, and indocyanine green?stained internal limiting membrane OD. Visual acuity improved, reaching 20/25 1 year after surgery despite the appearance of small preretinal flecks. Visual acuity OS decreased some time later and vitrectomy was performed when VA OS was 20/100. Three years after surgery, BCVA was 20/25 OD and 20/20 OS 1 year after surgery.


CONCLUSIONS
We describe a young patient with Gaucher disease with severe bilateral vitreous opacities and macular pucker. After surgery, vitreous opacities partially and progressively recurred, but the overall favorable outcome strongly supports a surgical approach in cases of this kind.
Department of Ophthalmology, Civil Hospital, San Donà di Piave, Italy.
Emilio
E
Rapizzi
Lorenzo
L
Vannozzi
Vanni
V
Borgioli
Fabrizio
F
Giansanti
Vittoria
V
Murro
Andrea
A
Sodi
Ugo
U
Menchini
D000293:Adolescent; D004396:Coloring Agents; D004596:Electroretinography; D019773:Epiretinal Membrane / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005074:Evoked Potentials, Visual; D005128:Eye Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005776:Gaucher Disease / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007208:Indocyanine Green; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology / Q000601:surgery*
D004396:Coloring Agents; D007208:Indocyanine Green