The inflammasome and alum-mediated adjuvanticity.
Recent reports have implicated the NLRP3-associated inflammasome in the adjuvanticity of alum. Here, we summarize the major findings and ask what this may mean for improving human vaccination.
Howard Hughes Medical Institute, Departments of Medicine, and Microbiology & Immunology, University of California San Francisco 513 Parnassus Avenue, S-1032B, San Francisco, CA 94143-0795 USA.
Suk-Jo
SJ
Kang
Richard M
RM
Locksley