[The protoskolicidal effect of 1% polyvinylpyrrolidone-iodine (PVP-1) and 2% taurolidine on abdominal hydatidosis].
The aim of this study is to determine the efficacy of 1% polyvinylprolidone-iodine (Betadine, PVP-I) and 2% Taurolidine as scolicidal agents for the prevention of abdominal hydatidosis defined as the rupture of the echinococcal cyst spontaneously or traumatically. The study was carried out in fifty mice randomly assigned into 5 treatment groups as following: group with no expose to any scolicidal agent, groups with 1% PVP-I for 2 and 5 minutes; groups with 2 % Taurolidine for 2 minutes, and 5 minutes. PVP-I has found to be effective according to results of staining with the eosin dye in vitro and abdominal hydatidosis in vivo, while Taurolidine was ineffective as a scolicidal agent.
Ekçı
Baki
B
Yeditepe University Hospital, Department of General Surgery, Istanbul, Turkey, Turkey.
Gürol
Yeşim
Y
Aydin
Ismail
I
Yalniz
Fırat
F
Ozcan
Murat
M
Zengın
Kaan
K
D000818:Animals; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D004443:Echinococcosis / Q000517:prevention & control* / Q000601:surgery; D048209:Echinococcus granulosus / Q000187:drug effects*; D006801:Humans; D051379:Mice; D011183:Postoperative Complications / Q000469:parasitology / Q000517:prevention & control; D011206:Povidone-Iodine / Q000494:pharmacology*; D011897:Random Allocation; D055502:Secondary Prevention; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D013829:Thiadiazines / Q000494:pharmacology*
D000891:Anti-Infective Agents, Local; D013829:Thiadiazines; D013654:Taurine; D011206:Povidone-Iodine; C012566:taurolidine