The role of TNF inhibitors in psoriasis therapy: new implications for associated comorbidities.
Over the past several years, tumor necrosis factor (TNF) antagonists have become first-line agents in the treatment of moderate-to-severe psoriasis. These medications are highly effective in treating both psoriasis and psoriatic arthritis and may also reduce the risk of cardiovascular events in patients with chronic inflammatory disorders. In this article we review the use of anti-TNF therapy in psoriasis and its implications in regards to the co-morbid conditions associated with psoriasis.
Yost
John
J
University of Michigan, Department of Dermatology 1910 Taubman Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109 USA.
Gudjonsson
Johann E
JE