[A case of tuberculous lateral great adductor muscle abscess during treatment of miliary tuberculosis].
We report a rare case of a thigh abscess which appeared during treatment of miliary tuberculosis. A 72-year-old woman with a history of diabetes mellitus was being treated for systemic sclerosis with prednisolone. She was then admitted to our hospital with fever, and chest computed tomography showed an abnormal shadow. She was given a diagnosis of miliary tuberculosis, and antituberculous therapy was initiated with isoniazid, rifampicin, ethambutol and pyrazinamide. Although this combination of antituberculous drugs was effective, 3 months after the initiation of treatment, a collection of fluid appeared in her left thigh. Further examination revealed the fluid to be positive for Mycobacterium tuberculosis on PCR and negative on mycobacterial culture. We thus diagnosed this phenomenon to be a paradoxical reaction.
Matsuyama
Takahiro
T
Division of Respiratory Medicine, Respirology and Stress Care Center, Kagoshima University Hospital.
Sadamura
Yukari
Y
Kawabata
Takashi
T
Momi
Hiroaki
H
Higashimoto
Ikkou
I
D000038:Abscess / Q000209:etiology* / Q000382:microbiology; D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage; D004977:Ethambutol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D011718:Pyrazinamide / Q000008:administration & dosage; D013848:Thigh; D014391:Tuberculosis, Miliary / Q000150:complications* / Q000188:drug therapy
D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid