Advances in the management of uterine fibroids.
Uterine fibroids are extremely common, with major surgery the current main management option; uterine artery embolisation is an alternative, but risks to fertility are unclear. Minimally invasive procedures are becoming more commonly performed via both the hysteroscope and laparoscope, minimising recovery time for patients. Recently, small doses of progesterone receptor modulators (mifepristone and asoprisnil) have been shown to be effective in reducing menstrual blood loss and fibroid size. Progress from here should include the development of a well-tolerated oral preparation that will maintain fertility.
Centre for Reproductive Biology, University of Edinburgh, The Queen&s Medical Research Institute Little France Crescent, Edinburgh EH16 4TJ UK.
Kirsty I
KI
Munro
Hilary Od
HO
Critchley