Enzymatic synthesis of palm olein-based fatty thiohydroxamic acids.
Fatty thiohydroxamic acids (FTAs) have been successfully synthesized from palm olein and thiohydroxamic acid by a one-step lipase catalyzed reaction. The use of immobilized lipase (Lipozyme RMIM) as the catalyst for the preparation reaction provides an easy isolation of the enzyme from the products and other components in the reaction mixture. The FTAs were characterized using Fourier transform infrared (FTIR) spectroscopy, proton nuclear magnetic resonance ((1)H NMR) technique and elemental analysis. The highest conversion percentage (95 %) was obtained when the process was carried out for 30 hours using urea to palm oil ratio of 6.0: 1.0 at 40 °C. The method employed offers several advantages such as renewable and abundant of the raw material, simple reaction procedure, environmentally friendly process and high yield of the product.
Department of Chemistry, Faculty of Science, University Putra Malaysia, Serdang, Selangor, Malaysia. emadaalmulla@yahoo.com
Emad A Jaffar
EA
Al-Mulla
Wan Md Zin Wan
WM
Yunus
Nor Azowa Bt
NA
Ibrahim
Mohd Zaki Ab
MZ
Rahman
D002384:Catalysis; D006877:Hydroxamic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D008049:Lipase; D000073878:Palm Oil; D010938:Plant Oils; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013997:Time Factors; D014508:Urea
D006877:Hydroxamic Acids; D010938:Plant Oils; D000073878:Palm Oil; D014508:Urea; C093666:Lipozyme; D008049:Lipase