Efficacy of induced luteinizing hormone surge after "trigger" with gonadotropin-releasing hormone agonist.
The magnitude of the LH surge after GnRH agonist "trigger" was correlated with oocyte yield and maturity and was suboptimal in approximately half of the cycles. A modest reduction in oocyte yield and maturity was observed when the serum level of LH 12 hours after GnRH agonist trigger was less than the median value (52 IU/L), and a dramatic reduction in yield and maturity was observed when that level was less than 12 IU/L.
Fertility Center of Las Vegas, Las Vegas, Nevada 78229, USA.
Bruce S
BS
Shapiro
Said T
ST
Daneshmand
Humberto
H
Restrepo
Forest C
FC
Garner
Martha
M
Aguirre
Cynthia
C
Hudson
D000328:Adult; D002452:Cell Count; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology / Q000627:therapeutic use*; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D007246:Infertility / Q000097:blood / Q000473:pathology / Q000628:therapy*; D007986:Luteinizing Hormone / Q000097:blood*; D054315:Oocyte Retrieval; D009865:Oocytes / Q000166:cytology / Q000473:pathology; D010062:Ovulation Induction / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D015854:Up-Regulation / Q000187:drug effects; D055815:Young Adult
D005300:Fertility Agents, Female; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone