Isolation of chemical constituents from Enicosanthum cupulare (King) Airy-Shaw.
Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine were isolated from this plant for the first time. In addition, we examined the effects of these compounds on melanogenesis in murine B16 melanoma cells; O-methylmoschatoline increased melanin content in these cells.
Fujita
Satoshi
S
Department of Chemistry, Faculty of Engineering, Gifu University, Gifu 501-1193, Japan.
Ninomiya
Masayuki
M
Efdi
Mai
M
Ohguchi
Kenji
K
Nozawa
Yoshinori
Y
Koketsu
Mamoru
M
D000818:Animals; D029061:Annonaceae / Q000737:chemistry*; D002850:Chromatography, Gel; D009682:Magnetic Resonance Spectroscopy; D008546:Melanoma, Experimental / Q000378:metabolism / Q000473:pathology; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D016339:Spectrometry, Mass, Fast Atom Bombardment
D010936:Plant Extracts