Generation of benzyne from benzoic acid using C-H activation.
ortho C-H activation of benzoic acids with Pd(II) generates an oxapalladacycle that can decarboxylate to produce a palladium-associated aryne. The arynes then undergo [2+2+2] trimerisation to afford triphenylenes.
Cant
Alastair A
AA
School of Chemistry, University of Edinburgh, King's Buildings, West Mains Rd, Edinburgh, UK.
Roberts
Lee
L
Greaney
Michael F
MF
D001555:Benzene Derivatives / Q000737:chemistry*; D019817:Benzoic Acid / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
D001555:Benzene Derivatives; C524146:benzyne; D010165:Palladium; D002244:Carbon; D006859:Hydrogen; D019817:Benzoic Acid