Nucleo-cytoplasmic transport of proteins and RNA in plants.
Transport of macromolecules between the nucleus and the cytoplasm is an essential necessity in eukaryotic cells, since the nuclear envelope separates transcription from translation. In the past few years, an increasing number of components of the plant nuclear transport machinery have been characterised. This progress, although far from being completed, confirmed that the general characteristics of nuclear transport are conserved between plants and other organisms. However, plant-specific components were also identified. Interestingly, several mutants in genes encoding components of the plant nuclear transport machinery were investigated, revealing differential sensitivity of plant-specific pathways to impaired nuclear transport. These findings attracted attention towards plant-specific cargoes that are transported over the nuclear envelope, unravelling connections between nuclear transport and components of signalling and developmental pathways. The current state of research in plants is summarised in comparison to yeast and vertebrate systems, and special emphasis is given to plant nuclear transport mutants.
Merkle
Thomas
T
Faculty of Biology, Institute for Genome Research and Systems Biology, University of Bielefeld, 33594 Bielefeld, Germany. tmerkle@cebitec.uni-bielefeld.de
D021581:Active Transport, Cell Nucleus; D000818:Animals; D017360:Arabidopsis; D029681:Arabidopsis Proteins / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D028884:Karyopherins / Q000378:metabolism; D009154:Mutation; D029543:Nucleocytoplasmic Transport Proteins / Q000235:genetics / Q000378:metabolism*; D010445:Peptide Elongation Factors / Q000378:metabolism; D063245:Plant Development; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism*; D018749:RNA, Plant / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D015398:Signal Transduction; D013045:Species Specificity; D020931:ran GTP-Binding Protein / Q000378:metabolism; D000097606:Exportin 1 Protein
D029681:Arabidopsis Proteins; D028884:Karyopherins; D029543:Nucleocytoplasmic Transport Proteins; D010445:Peptide Elongation Factors; D010940:Plant Proteins; D018749:RNA, Plant; D018160:Receptors, Cytoplasmic and Nuclear; D020931:ran GTP-Binding Protein; D000097606:Exportin 1 Protein; C541497:GFA1 protein, Arabidopsis