Self-reported and objectively measured activity related to biomarkers using NHANES.
OBJECTIVE
The purpose of this study was to examine the independent associations of self-reported and objectively measured (using accelerometers) moderate to vigorous physical activity (MVPA) with physiological and anthropometric biomarkers in a nationally representative sample of U.S. adults.


METHODS
Data from the cross-sectional National Health and Nutrition Examination Survey 2003-2006 data were analyzed. Adults 20 yr and older (N=5797) with self-reported PA and 4 d or more of accelerometer data were included in the analyses. Pregnant or lactating women were excluded. Outcomes were blood pressure, body mass index, waist circumference, triceps and subscapular skinfolds, cholesterol, triglyceride, C-reactive protein, homocysteine, and insulin resistance and hyperinsulinemia indices.


RESULTS
Objectively measured MVPA displayed stronger independent associations with the biomarkers than did self-reported MVPA, even after adjusting for sociodemographic and health factors (adjusted Wald F values=3.9-85.6, P<0.05-0.0001). Self-reported and objectively measured MVPA were independently associated with skinfold measures, HDL, and C-reactive protein when both were included in the model.


CONCLUSIONS
Objectively measured MVPA displayed stronger associations with physiological and anthropometric biomarkers than self-reported MVPA. However, self-reported and objectively measured MVPA appear to capture distinct aspects of PA that are independently associated with certain biomarkers. Further understanding of the distinct contributions of self-reported and objectively measured PA to health outcomes could help to better identify optimal activity level and pattern.
Atienza
Audie A
AA
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892-7335, USA. atienzaa@mail.nih.gov
Moser
Richard P
RP
Perna
Frank
F
Dodd
Kevin
K
Ballard-Barbash
Rachel
R
Troiano
Richard P
RP
Berrigan
David
D
D056044:Actigraphy / Q000295:instrumentation; D000328:Adult; D015415:Biomarkers; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D009749:Nutrition Surveys; D012044:Regression Analysis; D057566:Self Report; D014481:United States; D055815:Young Adult
D015415:Biomarkers