Effects of treadmill-walking training with additional body load on quality of life in subjects with Parkinson's disease.
BACKGROUND
Parkinson's disease (PD) causes motor and non-motor impairments that affect the subject's quality of life.


OBJECTIVE
To assess the effects of treadmill-walking training with additional body load on the quality of life and motor function of subjects with PD.


METHODS
Nine subjects with PD, Hoehn and Yahr stages 2-3, not demented and with capability to ambulate independently took part in this study. The training program was divided into three phases (A₁-B-A₂): treadmill training with additional body load (A₁), control condition (conventional physical therapy group; B) and a second period of treadmill training with load (A₂). Each phase lasted six weeks. Quality of life and motor function were assessed by the PDQ-39 and the motor score of the Unified Parkinson's Disease Rating Scale (UPDRS), respectively. The evaluations and the training were performed during the on-phase of the medication cycle.


RESULTS
There was improvement in the total PDQ-39 score across the training period. The subscores mobility, activities of daily living and cognition subscores significantly improved after the training period. The improvement in the total score was associated with motor and non-motor factors in all of the training phases. The UPDRS motor score also improved, however it did not present any association with the improvement in quality of life.


CONCLUSIONS
The results showed that the treadmill-walking training with additional body load allowed an improvement in motor and non-motor aspects related to quality of life and motor function in subjects with PD.
Filippin
Nadiesca T
NT
Physical Therapy Department, Laboratory of Neuroscience, Universidade Federal de São Carlos (UFSCar), São Carlos (SP), Brazil. nadifilippin@yahoo.com.br
da Costa
Paula H Lobo
PH
Mattioli
Rosana
R
D000368:Aged; D005081:Exercise Therapy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000534:rehabilitation*; D011788:Quality of Life; D016138:Walking; D016474:Weight-Bearing