A divergent strategy for the synthesis of secologanin derived natural products.
The syntheses of D,L-geissoschizol, D,L-corynantheidol, D,L-dihydrocorynantheol, D,L-protoemetinol, and D,L-3-epi-protoemetinol have been accomplished from a single synthetic intermediate.
English
Brandon J
BJ
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Williams
Robert M
RM
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry*; D057888:Iridoid Glucosides / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
D000470:Alkaloids; D001688:Biological Products; D057888:Iridoid Glucosides; C570572:protoemetinol; C021086:secologanin; C007137:corynantheidol