Gut commensal flora: tolerance and homeostasis.
Commensal microorganisms are not ignored by the intestinal immune system. Recent evidence shows that commensals actively participate in maintaining intestinal immune homeostasis by interacting with intestinal epithelial cells and delivering tolerogenic signals that are transmitted to the underlying cells of the immune system.
Rescigno
Maria
M
Department of Experimental Oncology, European Institute of Oncology Via Ripamonti 435, 20141 Milan Italy. maria.rescigno@ifom-ieo-campus.it