Adjuvant therapy with methylene blue in the treatment of right ventricular failure after pulmonary embolectomy.
Severe pulmonary embolism often leads to right ventricular failure after surgical embolectomy secondary to ischaemia reperfusion injury and acute lung injury (ALI). Acute right ventricular dysfunction is traditionally treated with inotropes and vasopressors to maintain cardiac output and coronary perfusion as well as selective pulmonary vasodilators to provide right ventricular afterload reduction. We report the first case of utilisation of methylene (MB) in a patient with acute right ventricular failure and vasoplegic shock after surgical pulmonary embolectomy.
Department of Anesthesiology and Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA. Jayashree.Raikhelkar@mountsinai.org
Jayashree K
JK
Raikhelkar
Federico
F
Milla
Bruce
B
Darrow
Corey
C
Scurlock
D000368:Aged; D017024:Chemotherapy, Adjuvant / Q000379:methods; D017128:Embolectomy; D004791:Enzyme Inhibitors / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008751:Methylene Blue / Q000008:administration & dosage*; D011655:Pulmonary Embolism / Q000601:surgery; D056987:Vasoplegia / Q000188:drug therapy* / Q000209:etiology; D018497:Ventricular Dysfunction, Right / Q000188:drug therapy* / Q000209:etiology
D004791:Enzyme Inhibitors; D008751:Methylene Blue