Fungal cyclooligomer depsipeptides: from classical biochemistry to combinatorial biosynthesis.
This review surveys the biological activities and the iterative and recursive biosynthetic mechanisms of fungal cyclooligomer depsipeptides, and their structural diversification by various combinatorial biosynthetic methods.
Süssmuth
Roderich
R
Technische Universität Berlin, Institut für Chemie, Berlin, Germany. suessmuth@chem.tu-berlin.de
Müller
Jane
J
von Döhren
Hans
H
Molnár
István
I
D020650:Combinatorial Chemistry Techniques; D047630:Depsipeptides / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D005658:Fungi / Q000737:chemistry*; D015394:Molecular Structure
D047630:Depsipeptides