Secondary absorbed doses from light ion irradiation in anthropomorphic phantoms representing an adult male and a 10 year old child.
Secondary organ absorbed doses were calculated by Monte Carlo simulations with the SHIELD-HIT07 code coupled with the mathematical anthropomorphic phantoms CHILD-HIT and ADAM-HIT. The simulated irradiations were performed with primary (1)H, (4)He, (7)Li, (12)C and (16)O ion beams in the energy range 100-400 MeV/u which were directly impinging on the phantoms, i.e. approximating scanned beams, and with a simplified beamline for (12)C irradiation. The evaluated absorbed doses to the out-of-field organs were in the range 10(-6) to 10(-1) mGy per target Gy and with standard deviations 0.5-20%. While the contribution to the organ absorbed doses from secondary neutrons dominated in the ion beams of low atomic number Z, the produced charged fragments and their subsequent charged secondaries of higher generations became increasingly important for the secondary dose delivery as Z of the primary ions increased. As compared to the simulated scanned (12)C ion beam, the implementation of a simplified beamline for prostate irradiation with (12)C ions resulted in an increase of 2-50 times in the organ absorbed doses depending on the distance from the target volume. Comparison of secondary organ absorbed doses delivered by (1)H and (12)C beams showed smaller differences when the RBE for local tumor control of the ions was considered and normalization to the RBE-weighted dose to the target was performed.
Medical Radiation Physics, Department of Physics, Stockholm University, Box 260, SE-17176 Stockholm, Sweden. martha.hultqvist@ki.se
Martha
M
Hultqvist
Irena
I
Gudowska
D000328:Adult; D002648:Child; D006801:Humans; D007287:Inorganic Chemicals / Q000009:adverse effects*; D008297:Male; D009010:Monte Carlo Method; D009502:Neutrons / Q000009:adverse effects; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011874:Radiometry / Q000295:instrumentation*
D007287:Inorganic Chemicals