Intra and interobserver reliability of the interpretation of high-resolution computed tomography on the lungs of premature infants.
OBJECTIVE
High-resolution computed tomography (HRCT) of the lungs is more sensitive than radiographs for evaluating pulmonary disease, but little has been described about HRCT interpretation during the neonatal period or shortly afterwards. The aim here was to evaluate the reliability of the interpretation of HRCT among very low birth weight premature infants (VLBWPI; < 1500 g).


METHODS
Cross-sectional study on intra and interobserver reliability of HRCT on VLBWPI.


METHODS
86 VLBWPI underwent HRCT. Two pediatric radiologists analyzed the HRCT images. The reliability was measured by the proportion of agreement, kappa coefficient (KC) and positive and negative agreement indices.


RESULTS
For radiologist A, the intraobserver reliability KC was 0.79 (confidence interval, CI: 0.54-1.00) for normal/abnormal examinations; for each abnormality on CT, KC ranged from 0.05 to 1.00. For radiologist B, the intraobserver reliability KC was 0.79 (CI: 0.54-1.00) for normal/abnormal examinations; for each abnormality on CT, KC ranged from 0.37 to 0.83. The interobserver agreement was 88% for normal/abnormal examinations and KC was 0.71 (CI: 0.5- 0.93); for most abnormal findings, KC ranged from 0.51-0.67.


CONCLUSIONS
For normal/abnormal examinations, the intra and interobserver agreements were substantial. For most of the imaging findings, the intraobserver agreement ranged from moderate to substantial. Our data demonstrate that in clinical practice, there is no reason for more than one tomographic image evaluator, provided that this person is well trained in VLBWPI HRCT interpretation. Analysis by different observers should be reserved for research and for difficult cases in clinical contexts.
Boëchat
Márcia Cristina Bastos
MC
Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. marciaboechat@iff.focruz.br
Mello
Rosane Reis de
RR
Dutra
Maria Virgínia Peixoto
MV
Silva
Kátia Silveira da
KS
Daltro
Pedro
P
Marchiori
Edson
E
D001997:Bronchopulmonary Dysplasia / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging*; D019102:Infant, Very Low Birth Weight; D008168:Lung / Q000000981:diagnostic imaging*; D015588:Observer Variation; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000706:statistics & numerical data