The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.
The biomedical research community relies on a diverse set of resources, both within their own institutions and at other research centers. In addition, an increasing number of shared electronic resources have been developed. Without effective means to locate and query these resources, it is challenging, if not impossible, for investigators to be aware of the myriad resources available, or to effectively perform resource discovery when the need arises. In this paper, we describe the development and use of the Biomedical Resource Ontology (BRO) to enable semantic annotation and discovery of biomedical resources. We also describe the Resource Discovery System (RDS) which is a federated, inter-institutional pilot project that uses the BRO to facilitate resource discovery on the Internet. Through the RDS framework and its associated Biositemaps infrastructure, the BRO facilitates semantic search and discovery of biomedical resources, breaking down barriers and streamlining scientific research that will improve human health.
Tenenbaum
Jessica D
JD
Duke Translational Medicine Institute, Duke University School of Medicine, Durham, NC, USA. jessie.tenenbaum@duke.edu
Whetzel
Patricia L
PL
Anderson
Kent
K
Borromeo
Charles D
CD
Dinov
Ivo D
ID
Gabriel
Davera
D
Kirschner
Beth
B
Mirel
Barbara
B
Morris
Tim
T
Noy
Natasha
N
Nyulas
Csongor
C
Rubenson
David
D
Saxman
Paul R
PR
Singh
Harpreet
H
Whelan
Nancy
N
Wright
Zach
Z
Athey
Brian D
BD
Becich
Michael J
MJ
Ginsburg
Geoffrey S
GS
Musen
Mark A
MA
Smith
Kevin A
KA
Tarantal
Alice F
AF
Rubin
Daniel L
DL
Lyster
Peter
P
D000818:Animals; D035843:Biomedical Research; D019295:Computational Biology; D003628:Database Management Systems; D004282:Documentation; D006801:Humans; D020407:Internet; D008490:Medical Informatics; D012660:Semantics; D057170:Translational Research, Biomedical; D014584:User-Computer Interface