[Case-Report: Reversal of a deep neuromuscular block with sugammadex after rapid sequence induction with high-dose rocuronium bromide].
Sugammadex can reverse rocuronium-induced muscular relaxation by encapsulation of steroidal muscle relaxants without muscarinergic side effects. Clinical studies show effective dose-dependent reversal of neuromuscular blockades after rocuronium and vecuronium. We report on a patient with deep neuromuscular block at the end of surgery following rapid sequence induction of anesthesia with high-dose rocuronium, who could rapidly be reversed without side effects after adequate i.v. sugammadex application.
Klinik für Anästhesie, Operative Intensiv- und Palliativmedizin am Städtischen Klinikum Solingen gGmbH. adam@klinikumsolingen.de
Christian
C
Adam
Thomas
T
Standl
D000732:Androstanols / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D000758:Anesthesia / Q000379:methods*; D017081:Cholecystectomy, Laparoscopic; D000075202:Contraindications; D005764:Gastroesophageal Reflux / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D011229:Preanesthetic Medication; D000077123:Rocuronium; D020181:Sleep Apnea, Obstructive / Q000150:complications; D013390:Succinylcholine; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000008:administration & dosage / Q000009:adverse effects
D000732:Androstanols; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D013390:Succinylcholine; D000077123:Rocuronium