Periodic peritonitis due to familial Mediterranean fever in a patient with systemic lupus erythematosus.
We report a patient with systemic lupus erythematosus (SLE) who showed periodic peritonitis with spontaneous remission. She showed compound heterozygous mutations in the MEFV gene, leading to the diagnosis of familial Mediterranean fever (FMF). Oral colchicine successfully reduced the severity and frequency of her peritonitis. SLE occasionally manifests abdominal symptoms, but in cases with periodic peritonitis, associated FMF should be considered as a possible cause.
Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto. matsuma@shinshu-u.ac.jp
Masayuki
M
Matsuda
Dai
D
Kishida
Ayako
A
Tsuchiya-Suzuki
Kazuhiro
K
Fukushima
Yasuhiro
Y
Shimojima
Masahide
M
Yazaki
Shu-ichi
S
Ikeda
D015746:Abdominal Pain / Q000209:etiology*; D000328:Adult; D002690:Chlamydia Infections / Q000175:diagnosis; D003078:Colchicine / Q000627:therapeutic use; D003598:Cytoskeletal Proteins / Q000235:genetics; D003937:Diagnosis, Differential; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D005260:Female; D006579:Heterozygote; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D020125:Mutation, Missense; D058729:Peripheral Arterial Disease / Q000209:etiology; D010538:Peritonitis / Q000188:drug therapy / Q000209:etiology*; D000071198:Pyrin; D012008:Recurrence; D014034:Toes / Q000098:blood supply
D003598:Cytoskeletal Proteins; C000604192:MEFV protein, human; D000071198:Pyrin; D003078:Colchicine