Intraductal papillary mucininous neoplasm of the bile ducts: multimodality assessment with pathologic correlation.
Mucin-producing intraductal papillary neoplasm (adenocarcinoma/adenoma) in the bile duct is becoming recognized as a specific type of neoplasm. Since, it bears a striking similarity to intraductal papillary mucinous neoplasms of the pancreas with regard to its histopathologic features, the term "intraductal papillary mucinous neoplasms of the bile duct" (IPMN-B) is frequently used, although no definite terminology or definition has been decided by World Health Organization. This neoplasm lacks ovarian-like stroma and communicates with the bile ducts, unlike biliary mucinous cystic neoplasm (MCN). On the other hand, malignant IPMN-B is categorized as an intraductal-growth type of intrahepatic cholangiocarcinoma (ICC). In comparison to other types of ICC, such as the mass-forming type and periductal-infiltrating type that have poor resectability and an unfavorable prognosis, malignant IPMN-B can be resected and demonstrates a more favorable prognosis. Meanwhile, unlike biliary MCN that is usually confined in a closed cyst, IPMN-B can spread along the mucosal surface of the bile ducts, and it should be widely resected. Therefore, multimodality assessment is needed to ensure the correct diagnosis of IPMN-B. We herein review the imaging findings of IPMN-B with pathologic correlation.
Takanami
Kentaro
K
Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Seiryomachi, Aoba-ku, Sendai, Japan. takanami@rad.med.tohoku.ac.jp
Yamada
Takayuki
T
Tsuda
Masashi
M
Takase
Kei
K
Ishida
Kazuyuki
K
Nakamura
Yasuhiro
Y
Kanno
Atsushi
A
Shimosegawa
Tooru
T
Unno
Michiaki
M
Takahashi
Shoki
S
D002288:Adenocarcinoma, Mucinous / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D000231:Adenocarcinoma, Papillary / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D001650:Bile Duct Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006801:Humans; D008113:Liver Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology
D003287:Contrast Media