Radiofrequency electrode vibration-induced shear wave imaging for tissue modulus estimation: a simulation study.
Quasi-static electrode displacement elastography, used for in-vivo imaging of radiofrequency ablation-induced lesions in abdominal organs such as the liver and kidney, is extended in this paper to dynamic vibrational perturbations of the ablation electrode. Propagation of the resulting shear waves into adjoining regions of tissue can be tracked and the shear wave velocity used to quantify the shear (and thereby Young's) modulus of tissue. The algorithm used utilizes the time-to-peak displacement data (obtained from finite element analyses) to calculate the speed of shear wave propagation in the material. The simulation results presented illustrate the feasibility of estimating the Young's modulus of tissue and is promising for characterizing the stiffness of radiofrequency-ablated thermal lesions and surrounding normal tissue.
Shyam
S
Bharat
Tomy
T
Varghese
D000465:Algorithms; D017115:Catheter Ablation / Q000295:instrumentation; D003198:Computer Simulation; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000295:instrumentation; D004566:Electrodes; D005240:Feasibility Studies; D020342:Finite Element Analysis; D008962:Models, Theoretical; D009038:Motion; D019047:Phantoms, Imaging; D013997:Time Factors; D014159:Transducers; D014732:Vibration