The effects of changing from isoflurane to desflurane on the recovery profile during the latter part of anesthesia.
It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery. We therefore evaluated the effects of changing isoflurane to desflurane on emergence and recovery. Eighty-two patients were randomly assigned to receive isoflurane (Group I) or desflurane (Group D) or to change from isoflurane to desflurane anesthesia (Group X). At the point when there was an hour until the operation would end, isoflurane was replaced with 1 MAC of desflurane in Group X, and isoflurane and desflurane were maintained at 1 MAC in Groups I and D. When the operation ended, we compared the emergence and recovery characteristics among the 3 groups. Compared with Group I, Group X showed faster emergence and recovery. Group X and Group D showed similar emergence and recovery. In conclusion, changing isoflurane to desflurane during the latter part of anesthesia improves emergence and recovery.
Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 156-576, Republic of Korea.
Hyun
H
Kang
Su-Man
SM
Cha
Sun-Gyoo
SG
Park
Yong-Hun
YH
Jung
Young-Cheol
YC
Woo
Jin-Yun
JY
Kim
Gill-Hoi
GH
Koo
Seong-Deok
SD
Kim
Chong-Wha
CW
Baek
D000293:Adolescent; D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D018685:Anesthetics, Inhalation; D000077335:Desflurane; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D007813:Laparotomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D055815:Young Adult
D018685:Anesthetics, Inhalation; D000077335:Desflurane; D007530:Isoflurane