[Cluster analysis in micrangium detection in malignant nasal and paranasal sinus tumor].
OBJECTIVE
To study the application of cluster analysis in micrangium detection in malignant nasal and paranasal sinus tumor.


METHODS
Microvessel density (MVD) counting and cluster analysis were used to detect the micrangium in patients with malignant nasal and paranasal sinus tumor to assess the association between the malignancy and MVD.


RESULTS
According to cluster analysis, the MVD counting could be clustered into two groups, and the MVD showed significant differences between the tumor tissues, adjacent normal tissue and the control group (P<0.01), a result consistent with that by analysis of variance of the MVD.


CONCLUSIONS
Cluster analysis can be used in clustering of MVD counting in malignant nasal and paranasal sinus tumor to simplify MVD counting, and offers an important analytic method for micrangium analysis in tumors.
Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Jinan University, and Department of Otorhinolaryngology, Medical College, Jinan University, Guangzhou 510630, China. jiahaiying79@126.com
Hai-ying
HY
Jia
Tian-shi
TS
Mo
Tao
T
Zhang
Yan-chun
YC
Shan
Ji-qun
JQ
Wang
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D008297:Male; D055806:Microvessels; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000098:blood supply* / Q000175:diagnosis; D055815:Young Adult