The psychiatric GWAS consortium: big science comes to psychiatry.
The Psychiatric GWAS Consortium was founded with the aim of conducting statistically rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders: ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia. In the era of GWAS and high-throughput genomics, a major trend has been the emergence of collaborative, consortia approaches. Taking advantage of the scale that collaborative consortia approaches can bring to a problem, the PGC has been a major driver in psychiatric genetics and provides a model for how similar approaches may be applied to other disease communities.
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Patrick F
PF
Sullivan
D055106:Genome-Wide Association Study / Q000266:history / Q000639:trends; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D015201:Meta-Analysis as Topic; D009446:Neurobiology / Q000266:history / Q000379:methods / Q000639:trends; D011570:Psychiatry / Q000379:methods / Q000639:trends