Antimicrobial lock solutions: an approach to reduce catheter-related bacteremia.
Catheters create a highway for bacteria to migrate into the bloodstream and are associated with increased mortality. Infections associated with catheter use contribute to making infection the second leading cause of death in patients with ESRD. This article reviews the growing research that indicates antimicrobial catheter-locking solutions are effective at preventing catheter-related bacteremia by inhibiting the growth of biofilm containing organisms in a catheter lumen and preventing colonization of bacteria.
The Florida ESRD Network, Tampa, FL, USA. dkulawik@nw7.esrd.net
Deuzimar
D
Kulawik
D000890:Anti-Infective Agents / Q000008:administration & dosage*; D016470:Bacteremia / Q000517:prevention & control*; D002404:Catheterization / Q000009:adverse effects*; D004509:Education, Nursing, Continuing; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D012996:Solutions
D000890:Anti-Infective Agents; D012996:Solutions