In vivo biofilm formation on a soft denture liner in elderly patients with controlled diabetes.
OBJECTIVE
This in vivo study evaluated the influence of controlled diabetes on biofilm formation on a soft denture liner in elderly patients.


BACKGROUND
Soft denture lining materials are more susceptible to microbial colonisation than denture base acrylic resins. Especially in the elderly, several predisposing factors may accumulate leading to an increased probability of biofilm development that may result in candidiasis, a significant clinical oral disease.


METHODS
Volunteers wearing complete dentures were divided into two groups (n = 20): diabetic patients with controlled glycaemia, and healthy patients. In both groups, a silicone-based soft liner was placed in a recess created at the base of the maxillary dentures. Subjects cleaned the prosthesis three times a day. Biofilm formed on the liner was quantified at various time points (baseline, two, four and six weeks). Data were analysed by two-way repeated measures ANOVA and Tukey's test (α = 0.05).


RESULTS
There was no statistical difference in biofilm formation for any of the time points between controlled diabetes patients and healthy patients.


CONCLUSIONS
The results suggest that the control of diabetes in elderly patients provides the same levels of biofilm formation when compared to healthy individuals.
School of Dentistry, West University of Santa Catarina, SC, Brazil.
Daniela R
DR
Faccio
Tatiana
T
Pereira-Cenci
Maximiliano S
MS
Cenci
Flávio F
FF
Demarco
Rafael R
RR
Moraes
Noéli
N
Boscato
D000368:Aged; D018441:Biofilms / Q000254:growth & development*; D001786:Blood Glucose / Q000032:analysis; D004396:Coloring Agents; D003764:Dental Materials / Q000737:chemistry*; D003802:Dentifrices / Q000627:therapeutic use; D003822:Denture Liners / Q000382:microbiology*; D003827:Denture, Complete, Upper / Q000382:microbiology; D003920:Diabetes Mellitus / Q000382:microbiology / Q000517:prevention & control*; D005500:Follow-Up Studies; D006801:Humans; D009499:Neutral Red; D012307:Risk Factors; D012826:Silicone Elastomers / Q000737:chemistry; D014099:Toothbrushing / Q000295:instrumentation
D001786:Blood Glucose; D004396:Coloring Agents; D003764:Dental Materials; D003802:Dentifrices; D012826:Silicone Elastomers; D009499:Neutral Red