Effect of acupuncture on assisted reproduction treatment outcomes.
BACKGROUND
Acupuncture has recently been used as a complementary technique in the management of infertility. It has physiological and psychological effects and may be considered an alternative for stress reduction in women undergoing infertility treatments.


OBJECTIVE
To examine the hypothesis that acupuncture treatment may increase the pregnancy rate in patients undergoing intracytoplasmic sperm injection cycles.


METHODS
Patients enrolled in the study were stratified according to age and randomised to either a control group (n=208) or acupuncture group, (n=208). The pregnancy, implantation and abortion rates of the two groups were compared.


RESULTS
No influence of acupuncture treatment on clinical outcomes was seen; however, when cycles in which the causes of infertility were exclusively tubal-uterine or idiopathic were evaluated separately, a positive influence of acupuncture on pregnancy (OR=5.15, 95% CI 1.03 to 34.5; p=0.048) was noted. Moreover, trends toward an increase in implantation were seen when acupuncture was performed (regression coefficient: 0.645; p=0.092).


CONCLUSIONS
The results suggest that acupuncture treatment had no influence when performed immediately before and immediately after embryo transfer, on clinical outcomes overall. In a subgroup analysis, when the embryo was not affected by an ovarian or seminal influence, a benefit was noted.
Madaschi
Camila
C
Fertility - Assisted Fertilization Center, São Paulo - SP 01401-002, Brazil.
Braga
Daniela Paes Almeida Ferreira
DP
Figueira
Rita de Cássia Savio
Rde C
Iaconelli
Assumpto
A
Borges
Edson
E
D000022:Abortion, Spontaneous / Q000453:epidemiology; D015670:Acupuncture Therapy / Q000379:methods*; D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D050498:Live Birth / Q000453:epidemiology; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted; D016896:Treatment Outcome; D055815:Young Adult