Selective determination of melamine in aqueous medium by molecularly imprinted solid phase extraction.
A molecularly imprinted polymer able to recognize melamine in partially aqueous medium was synthesized using methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linking agent. The bound specificity and selectivity of the obtained material were verified by performing binding experiments with melamine and its structural analogue, 2,4,6-trimethoxy-1,3,5-triazine, respectively, using different aqueous binding media. Finally, the ability of MIP to selectively extract melamine from two real samples, a food supplement and a freeze-dried meat sample, was demonstrated.
Curcio
Manuela
M
Dipartimento di Scienze Farmaceutiche, Edificio Polifunzionale, Università della Calabria, Arcavacata di Rende (CS) 87036, Italy. manuela.curcio@unical.it
Puoci
Francesco
F
Cirillo
Giuseppe
G
Iemma
Francesca
F
Spizzirri
Umile Gianfranco
UG
Picci
Nevio
N
D000327:Adsorption; D000818:Animals; D019587:Dietary Supplements / Q000032:analysis; D005506:Food Contamination / Q000032:analysis; D008461:Meat Products / Q000032:analysis; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014227:Triazines / Q000032:analysis / Q000302:isolation & purification*
D011108:Polymers; D014227:Triazines; C011907:melamine