The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.
The biomedical research community relies on a diverse set of resources, both within their own institutions and at other research centers. In addition, an increasing number of shared electronic resources have been developed. Without effective means to locate and query these resources, it is challenging, if not impossible, for investigators to be aware of the myriad resources available, or to effectively perform resource discovery when the need arises. In this paper, we describe the development and use of the Biomedical Resource Ontology (BRO) to enable semantic annotation and discovery of biomedical resources. We also describe the Resource Discovery System (RDS) which is a federated, inter-institutional pilot project that uses the BRO to facilitate resource discovery on the Internet. Through the RDS framework and its associated Biositemaps infrastructure, the BRO facilitates semantic search and discovery of biomedical resources, breaking down barriers and streamlining scientific research that will improve human health.
Duke Translational Medicine Institute, Duke University School of Medicine, Durham, NC, USA. jessie.tenenbaum@duke.edu
Jessica D
JD
Tenenbaum
Patricia L
PL
Whetzel
Kent
K
Anderson
Charles D
CD
Borromeo
Ivo D
ID
Dinov
Davera
D
Gabriel
Beth
B
Kirschner
Barbara
B
Mirel
Tim
T
Morris
Natasha
N
Noy
Csongor
C
Nyulas
David
D
Rubenson
Paul R
PR
Saxman
Harpreet
H
Singh
Nancy
N
Whelan
Zach
Z
Wright
Brian D
BD
Athey
Michael J
MJ
Becich
Geoffrey S
GS
Ginsburg
Mark A
MA
Musen
Kevin A
KA
Smith
Alice F
AF
Tarantal
Daniel L
DL
Rubin
Peter
P
Lyster
D000818:Animals; D035843:Biomedical Research; D019295:Computational Biology; D003628:Database Management Systems; D004282:Documentation; D006801:Humans; D020407:Internet; D008490:Medical Informatics; D012660:Semantics; D057170:Translational Research, Biomedical; D014584:User-Computer Interface