Intervention in at-risk states for developing psychosis.
Indicated prevention is currently one of the most promising approaches to fight the individual and societal burden associated with psychosis and particularly schizophrenia. The number of studies is still limited, yet encouraging results have been reported from pharmacological and psychotherapeutic trials. Furthermore, it has become clear that persons characterized by the at-risk criteria are already ill and do not only need preventive intervention but also treatment. As is indicated by a recent study successfully using omega-3 fatty acids for both purposes, it may be promising to develop and investigate interventions especially for the at-risk state, independent of their effectiveness in manifest disease states. An overview on the current findings and ongoing research in this area is provided.
Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany. stephan.ruhrmann@uk-koeln.de
Stephan
S
Ruhrmann
Frauke
F
Schultze-Lutter
Andreas
A
Bechdolf
Joachim
J
Klosterkötter
D014150:Antipsychotic Agents / Q000627:therapeutic use*; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy / Q000628:therapy*; D011613:Psychotherapy / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
D014150:Antipsychotic Agents; D015525:Fatty Acids, Omega-3