C-F Bond Formation for the Synthesis of Aryl Fluorides.
A selection of carbon-fluorine bond-forming reactions is presented with particular focus on transition metal-mediated fluorination. A brief summary of conventional fluorination reactions is followed by a discussion of fluorination reactions mediated by palladium and silver. Investigations into the mechanism as well as the conceptual difficulty associated with transition metal-mediated carbon-fluorine bond formation are presented.
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA.
Takeru
T
Furuya
Johannes E M N
JE
Klein
Tobias
T
Ritter