[Analgesic therapy of calciphylaxis with levomethadone : a case study].
Calciphylaxis, or calcific uremic arteriopathy, is a rare complication of end-stage renal impairment. It is characterized by calcification of arterioles and development of intensely painful subcutaneous ischemic ulcerations. While symptomatic management is the mainstay of treatment, particular emphasis is placed on adequate analgesia. Conventional analgesic concepts have mostly proved to be insufficient which increases the extreme suffering of patients. This case report describes the successful analgesic treatment of calciphylaxis with levomethadone.
Klinik für Anästhesiologie und Operative Intensivmedizin, Krankenhaus Merheim, Klinikum der Privaten Universität Witten/Herdecke, Ostmerheimerstr. 200, 51109 Köln, Deutschland. poelsm@kliniken-koeln.de
M
M
Poels
R
R
Joppich
K
K
Gerbershagen
F
F
Wappler
D000368:Aged; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use*; D002115:Calciphylaxis / Q000188:drug therapy* / Q000523:psychology / Q000601:surgery; D003131:Combined Modality Therapy; D003299:Cooperative Behavior; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D033183:Interdisciplinary Communication; D007676:Kidney Failure, Chronic / Q000150:complications; D007871:Leg Ulcer / Q000188:drug therapy / Q000523:psychology / Q000601:surgery; D008691:Methadone / Q000009:adverse effects / Q000627:therapeutic use*; D010147:Pain Measurement / Q000187:drug effects; D010148:Intractable Pain / Q000188:drug therapy* / Q000523:psychology; D010166:Palliative Care; D006435:Renal Dialysis; D013237:Stereoisomerism
D000701:Analgesics, Opioid; D008691:Methadone