Aortic aneurysm with severe aortic regurgitation in a patient with systemic lupus erythematosus.
A 37-year-old man was admitted to our hospital for precordial chest pain. He had taken prednisolone (5 mg/day) for systemic lupus erythematosus (SLE) and had been symptom free for the past 12 years. Echocardiography and contrast-enhanced CT of chest showed an enlarged ascending aortic aneurysm, which is rarely seen in SLE. Severe aortic regurgitation was also present, and surgical replacement of the ascending aorta and aortic valve was successfully accomplished by the Bentall procedure. Medial cystic necrosis in the ascending aorta, which is rarely seen in SLE angiopathy, was confirmed by histology. There were no significant histopathological findings in the aortic valve.
Miyashita
Tomoko
T
Department of Internal Medicine, Osaka City General Hospital. minet56@yahoo.co.jp
Abe
Yukio
Y
Kato
Yasuyuki
Y
Nakagawa
Eiichiro
E
Komatsu
Ryushi
R
Hattori
Koji
K
Shibata
Toshihiko
T
Yoshioka
Katsunobu
K
Naruko
Takahiko
T
Itoh
Akira
A
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D001011:Aorta / Q000601:surgery; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001027:Aortography; D019917:Blood Vessel Prosthesis Implantation; D002637:Chest Pain / Q000209:etiology; D018618:Echocardiography, Doppler, Color; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008297:Male; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents