DNA-controlled assembly of a NaTl lattice structure from gold nanoparticles and protein nanoparticles.
The formation of diamond structures from tailorable building blocks is an important goal in colloidal crystallization because the non-compact diamond lattice is an essential component of photonic crystals for the visible-light range. However, designing nanoparticle systems that self-assemble into non-compact structures has proved difficult. Although several methods have been proposed, single-component nanoparticle assembly of a diamond structure has not been reported. Binary systems, in which at least one component is arranged in a diamond lattice, provide alternatives, but control of interparticle interactions is critical to this approach. DNA has been used for this purpose in a number of systems. Here we show the creation of a non-compact lattice by DNA-programmed crystallization using surface-modified Qβ phage capsid particles and gold nanoparticles, engineered to have similar effective radii. When combined with the proper connecting oligonucleotides, these components form NaTl-type colloidal crystalline structures containing interpenetrating organic and inorganic diamond lattices, as determined by small-angle X-ray scattering. DNA control of assembly is therefore shown to be compatible with particles possessing very different properties, as long as they are amenable to surface modification.
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.
Petr
P
Cigler
Abigail K R
AK
Lytton-Jean
Daniel G
DG
Anderson
M G
MG
Finn
Sung Yong
SY
Park
D001483:Base Sequence; D003102:Colloids; D003460:Crystallization; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004867:Equipment Design; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008958:Models, Molecular; D036103:Nanotechnology; D053838:Scattering, Small Angle; D012964:Sodium / Q000737:chemistry*; D013793:Thallium / Q000737:chemistry*; D014771:Virion / Q000737:chemistry / Q000648:ultrastructure; D014961:X-Ray Diffraction
D003102:Colloids; D006046:Gold; D004247:DNA; D012964:Sodium; D013793:Thallium