Encoding of motor skill in the corticomuscular system of musicians.
How motor skills are stored in the nervous system represents a fundamental question in neuroscience. Although musical motor skills are associated with a variety of adaptations [1-3], it remains unclear how these changes are linked to the known superior motor performance of expert musicians. Here we establish a direct and specific relationship between the functional organization of the corticomuscular system and skilled musical performance. Principal component analysis was used to identify joint correlation patterns in finger movements evoked by transcranial magnetic stimulation over the primary motor cortex while subjects were at rest. Linear combinations of a selected subset of these patterns were used to reconstruct active instrumental playing or grasping movements. Reconstruction quality of instrumental playing was superior in skilled musicians compared to musically untrained subjects, displayed taxonomic specificity for the trained movement repertoire, and correlated with the cumulated long-term training exposure, but not with the recent past training history. In violinists, the reconstruction quality of grasping movements correlated negatively with the long-term training history of violin playing. Our results indicate that experience-dependent motor skills are specifically encoded in the functional organization of the primary motor cortex and its efferent system and are consistent with a model of skill coding by a modular neuronal architecture [4].
Human Cortical Physiology and Motor Control Laboratory, Department of Neurology, University of Wuerzburg, Josef-Schneider-Strasse 11, Wuerzburg, Germany.
Reinhard
R
Gentner
Susanne
S
Gorges
David
D
Weise
Kristin
K
aufm Kampe
Mathias
M
Buttmann
Joseph
J
Classen
D000328:Adult; D000704:Analysis of Variance; D001696:Biomechanical Phenomena; D016000:Cluster Analysis; D005260:Female; D005385:Fingers / Q000502:physiology*; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009048:Motor Skills / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D009146:Music; D025341:Principal Component Analysis; D011597:Psychomotor Performance / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation / Q000379:methods