Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event.
Lee
Hong Geun
HG
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
Ahn
Jae Young
JY
Lee
Amy S
AS
Shair
Matthew D
MD
D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018360:Crystallography, X-Ray; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure; D013237:Stereoisomerism; D000095602:Angucyclines and Angucyclinones
D000903:Antibiotics, Antineoplastic; D005449:Fluorenes; C433842:lomaiviticin A; D000095602:Angucyclines and Angucyclinones; C433843:lomaiviticin B