Fungal cyclooligomer depsipeptides: from classical biochemistry to combinatorial biosynthesis.
This review surveys the biological activities and the iterative and recursive biosynthetic mechanisms of fungal cyclooligomer depsipeptides, and their structural diversification by various combinatorial biosynthetic methods.
Technische Universität Berlin, Institut für Chemie, Berlin, Germany. suessmuth@chem.tu-berlin.de
Roderich
R
Süssmuth
Jane
J
Müller
Hans
H
von Döhren
István
I
Molnár
D020650:Combinatorial Chemistry Techniques; D047630:Depsipeptides / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D005658:Fungi / Q000737:chemistry*; D015394:Molecular Structure
D047630:Depsipeptides