Linc-ing Long noncoding RNAs and enhancer function.
Enhancers are distal regulatory sequences that control gene expression in development. Ørom et al. now report in Cell that some long noncoding RNAs have functional properties of enhancers. Known enhancers are also transcribed in cells in which they are active, suggesting that noncoding RNAs are integral to enhancer action.
Mattick
John S
JS
Institute for Molecular Bioscience, University of Queensland, St. Lucia QLD 4072, Australia. j.mattick@imb.uq.edu.au