Orbital nerve sheath myxoma: a case report.
A 72-year-old man was referred to the Service of Ophthalmology due to a 2-year history of ptosis and a painless mass in the lateral orbital margin of the right eye. Orbital MRI revealed a well-demarcated lesion in the superotemporal quadrant of the orbit. After surgical excision, histopathological examination led to the diagnosis of nerve sheath myxoma, a tumor composed of myxoid nodules separated by fibrous septa with spindle-shaped and stellate cells. Many of these cells were immunostained with antibodies to S-100 protein. This is the first case reported in the literature of such a tumor located in the orbit, and, though extremely rare, it should be considered in the differential diagnosis of orbital tumors.
Service of Ophthalmology, University Hospital, La Paz, Madrid, Spain. msorgaz@gmail.com
Margarita
M
Sánchez-Orgaz
Anna
A
Grabowska
Alvaro
A
Arbizu-Duralde
Ricardo
R
Romero-Martín
Mercedes
M
Patrón
Elisa
E
Diéguez
Miguel A
MA
García-Cabezas
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018321:Neurothekeoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009918:Orbital Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis
D014408:Biomarkers, Tumor; D009418:S100 Proteins