Intrathecal colistin for treatment of multidrug resistant (MDR) Pseudomonas aeruginosa after neurosurgical ventriculitis.
Cerebrospinal fluid (CSF) shunts significantly improve the quality of life in patients with acute hydrocephalus. However, infections associated with a CSF shunt constitute a severe complication with high morbidity and mortality. We describe a case of CFS shunt infection cured with intrathecal colistin.
Struttura Complessa di Anestesia e Terapia Intensiva, ULSS, Bassano del Grappa, Vicenza, Italy.
Marco
M
Baiocchi
Vincenzo
V
Catena
Stefano
S
Zago
Luigi
L
Badolati
Monica
M
Baccarin
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D002462:Cell Membrane / Q000187:drug effects; D002543:Cerebral Hemorrhage / Q000150:complications; D058565:Cerebral Ventriculitis / Q000188:drug therapy* / Q000209:etiology; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D003091:Colistin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000209:etiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D003091:Colistin