The inflammasome and alum-mediated adjuvanticity.
Recent reports have implicated the NLRP3-associated inflammasome in the adjuvanticity of alum. Here, we summarize the major findings and ask what this may mean for improving human vaccination.
Kang
Suk-Jo
SJ
Howard Hughes Medical Institute, Departments of Medicine, and Microbiology & Immunology, University of California San Francisco 513 Parnassus Avenue, S-1032B, San Francisco, CA 94143-0795 USA.
Locksley
Richard M
RM