Disseminated superficial actinic porokeratosis: a treatment review.
Disseminated superficial actinic porokeratosis (DSAP) is a chronic disorder of keratinization characterized by numerous papules and plaques distributed over sun-exposed sites. Treatments are poorly standardized and several investigational therapies have demonstrated limited success in treating DSAP. To our knowledge, there have been no systematic reviews of the literature regarding the treatment of this disease. Herein, we review recent studies pertaining to the treatment of DSAP and evaluate the level of evidence for each of these therapeutic modalities.
University of Maryland School of Medicine, Baltimore, MD, USA.
Hadas
H
Skupsky
Jonathan
J
Skupsky
Gary
G
Goldenberg
D000622:Aminolevulinic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D000634:Aminoquinolines / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002762:Cholecalciferol / Q000031:analogs & derivatives; D004008:Diclofenac / Q000627:therapeutic use; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D000077271:Imiquimod; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007369:Interferon Inducers / Q000627:therapeutic use; D053685:Laser Therapy; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D017499:Porokeratosis / Q000188:drug therapy*; D012176:Retinoids / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use
D000634:Aminoquinolines; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D007369:Interferon Inducers; D017319:Photosensitizing Agents; D012176:Retinoids; D014815:Vitamins; D004008:Diclofenac; D002762:Cholecalciferol; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid; D000077271:Imiquimod; D005472:Fluorouracil