Pyuria is absent during urinary tract infections in neutropenic patients.
To investigate the diagnostic significance of a normal urine sediment in the work-up for fever of unknown origin in neutropenia. Urinary tract infection was defined as ≥10(5) urinary pathogens in the absence of another focus. Pyuria was found in only 1/23 neutropenic episodes compared to 21/31 in controls (P < 0.0001).
Department of Pediatric Oncology-Hematology, VU Medical Center, Amsterdam, The Netherlands.
I L M
IL
Klaassen
V
V
de Haas
J A E
JA
van Wijk
G J L
GJ
Kaspers
M
M
Bijlsma
A
A
Bökenkamp
D002648:Child; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000150:complications* / Q000382:microbiology; D011379:Prognosis; D011776:Pyuria / Q000175:diagnosis*; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000209:etiology; D014556:Urine / Q000382:microbiology*