[Bone mineral density in residents living on radioactive territories of Cheliabinsk Region].
Operation of "Mayak" plutonium production complex resulted in radioactive contamination of the part of Chelyabinsk Region in 1950-60s. Significant gas-aerosol emissions of 1311 occurred since 1948; in 1957, a radiation accident resulted in 90Sr contamination of large territories. This paper presents comparison of bone mineral density of persons lived on territories with different levels of soil 90Sr-contamination with a control group. It was found that in 1970-1975 the bone mineral density, estimated from mineral content in bone samples, in residents of contaminated areas born in 1936-1952 was significantly lower compared with the control group. For persons born in 1880-1935 such differences were not found. It was shown that the decrease in bone mineral density was not related to 90Sr exposure of osteogenic cells in the dose range from 0.1 to 1300 mGy: the coefficient of correlation between individual 90Sr-doses and bone mineral contents was not significant. The decrease in bone mineral density of persons born in 1936-1952 could be associated with exposure of thyroid and parathyroid glands (systemic regulators of calcium turnover) by 131I from gas-aerosol emissions from "Mayak". Maximum gas-aerosol emissions occurred in 1948-1954 and coincided with growth and development of thyroid gland, characterizing by intensive accumulation of 131I, and with growth and maturation of the skeleton of persons born in these calendar years.
Tolstykh
E I
EI
Shagina
N B
NB
Peremyslova
L M
LM
Degteva
M O
MO
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000528:radiation effects*; D001853:Bone Marrow / Q000528:radiation effects; D001842:Bone and Bones / Q000378:metabolism / Q000528:radiation effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods*; D018788:Radioactive Hazard Release; D012800:Siberia; D012990:Soil Pollutants, Radioactive / Q000032:analysis* / Q000493:pharmacokinetics; D013326:Strontium Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics; D055815:Young Adult
D012990:Soil Pollutants, Radioactive; D013326:Strontium Radioisotopes