A curated online resource for SOX10 and pigment cell molecular genetic pathways.
We describe the creation of a specialized web-accessible database named the Pigment Cell Gene Resource, which contains information on the genetic pathways that regulate pigment cell development and function. This manually curated database is comprised of two sections, an annotated literature section and an interactive transcriptional network diagram. Initially, this database focuses on the transcription factor SOX10, which has essential roles in pigment cell development and function, but the database has been designed with the capacity to expand in the future, allowing inclusion of many more pigmentation genes. Database URL: http://research.nhgri.nih.gov/pigment_cell/
Baxter
Laura L
LL
Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Moreland
R Travis
RT
Nguyen
Anh-Dao
AD
Wolfsberg
Tyra G
TG
Pavan
William J
WJ
D000818:Animals; D030541:Databases, Genetic; D053263:Gene Regulatory Networks / Q000235:genetics*; D006801:Humans; D020407:Internet; D008544:Melanocytes / Q000166:cytology* / Q000378:metabolism; D051379:Mice; D058977:Molecular Sequence Annotation; D009154:Mutation / Q000235:genetics; D010858:Pigmentation / Q000235:genetics*; D055757:SOXE Transcription Factors / Q000235:genetics*; D014584:User-Computer Interface; D015027:Zebrafish / Q000235:genetics
D055757:SOXE Transcription Factors