SEOM clinical guidelines for the treatment of advanced colorectal cancer.
Colorectal cancer is the first cause of cancer diagnosis in Spain. Over half of the patients are diagnosed with or will eventually develop distant metastasis. The current manuscript aims to provide synthetic practical guidelines for the therapeutic approaches in advanced disease. Available systemic therapeutic options, and integration and sequencing of chemotherapy with surgical procedures are discussed. Extent of disease, treatment objective, tumor kras mutation status, as well as patient's functional and comorbid conditions shall be considered to properly design the most adequate therapeutic strategy.
Oncology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.
Rocío
R
García-Carbonero
M Auxiliadora
MA
Gómez España
Enrique
E
Casado Sáenz
Vicente
V
Alonso Orduña
Andrés
A
Cervantes Ruipérez
Javier
J
Gallego Plazas
Pilar
P
García Alfonso
Ignacio
I
Juez Martel
Encarnación
E
González Flores
María
M
Lomas Garrido
Dolores
D
Isla Casado
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