Terpenoids from the aerial parts of Parasenecio deltophylla.
Five new modified eremophilane-type sesquiterpenes (1-5), including three norsesquiterpenes (1-3), and one new monoterpene (6) were isolated from the aerial parts of Parasenecio deltophylla. Their structures were established on the basis of HRMS and NMR methods. The cytotoxicity of compounds 1-4 and 6 against selected cancer cell lines, including human promyelocytic leukemia (HL-60) and human hepatoma (Hep-G2), was evaluated. Antioxidant activities of these compounds were assessed by ABTS and DPPH methods.
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
Guo-Du
GD
Huang
Yong-Jin
YJ
Yang
Wang-Suo
WS
Wu
Ying
Y
Zhu
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D052160:Benzothiazoles / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013451:Sulfonic Acids / Q000494:pharmacology
C554328:3-O-palmitoylloliolide; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D010851:Picrates; D012717:Sesquiterpenes; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl