Homozygous mutation in SCN5A associated with atrial quiescence, recalcitrant arrhythmias, and poor capture thresholds.
Lopez
Keila N
KN
Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030, USA. knlopez@bcm.edu
Decker
Jamie A
JA
Friedman
Richard A
RA
Kim
Jeffrey J
JJ
D000638:Amiodarone / Q000008:administration & dosage; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage; D001145:Arrhythmias, Cardiac / Q000235:genetics*; D002304:Cardiac Pacing, Artificial; D016887:Cardiopulmonary Resuscitation; D002648:Child; D004200:Diseases in Twins / Q000235:genetics*; D004562:Electrocardiography; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006325:Heart Atria / Q000503:physiopathology*; D006720:Homozygote; D006801:Humans; D062554:NAV1.5 Voltage-Gated Sodium Channel; D012008:Recurrence; D015222:Sodium Channels / Q000235:genetics*; D017180:Tachycardia, Ventricular / Q000235:genetics / Q000628:therapy
D000889:Anti-Arrhythmia Agents; D062554:NAV1.5 Voltage-Gated Sodium Channel; C568320:SCN5A protein, human; D015222:Sodium Channels; D000638:Amiodarone