Two-year clinical outcomes after large coronary stent (4.0 mm) placement: comparison of bare-metal stent versus drug-eluting stent.
BACKGROUND
The absolute benefit of drug-eluting stents (DES) in low-risk patients and lesions is not well established.


OBJECTIVE
The long term clinical outcomes after percutaneous coronary intervention in a single coronary artery disease may not be affected by the type of stent.


METHODS
This study assessed and compared 2-year clinical outcomes of 304 consecutive patients (147 BMS patients and 157 DES patients) treated with a single coronary stent (4.0 mm) for single de novo large coronary artery disease in 3 referral cardiac centers. The primary outcome was a composite of major adverse cardiac events at 2 years after the index procedure.


RESULTS
The reference vessel diameter was similar in both groups (3.92 ± 0.29 mm in BMS vs 3.95 ± 0.24 mm in DES, P = 0.50). Late loss was larger in the BMS group (1.04 ± 0.83 mm vs 0.73 ± 0.91 mm in DES, P = 0.03). The incidence of major adverse cardiac events at the 2-year clinical follow-up was very low, 24 of 304 patients (7.9%), regardless of stent type deployed (7.5% in BMS vs 8.3% in DES, P = 0.83). The rate of target vessel revascularization was also similar in both groups (4.8% in BMS vs 5.7% in DES, P = 0.80).


CONCLUSIONS
Two-year clinical outcomes after PCI with a single large coronary stent (4.0 mm) were excellent. The clinical outcomes were not affected by the type of stent used.
Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Hyun-Tae
HT
Kim
Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Chang-Wook
CW
Nam
Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Seung-Ho
SH
Hur
Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Kwon-Bae
KB
Kim
Yeungnam University Hospital, Daegu, Republic of Korea.
Sang-Hee
SH
Lee
Yeungnam University Hospital, Daegu, Republic of Korea.
Geu-Ru
GR
Hong
Yeungnam University Hospital, Daegu, Republic of Korea.
Jong-Seon
JS
Park
Yeungnam University Hospital, Daegu, Republic of Korea.
Young-Jo
YJ
Kim
Inje University Busan Paik Hospital, Busan, Republic of Korea.
Ung
U
Kim
Inje University Busan Paik Hospital, Busan, Republic of Korea.
Tae-Hyun
TH
Yang
Inje University Busan Paik Hospital, Busan, Republic of Korea.
Doo-Il
DI
Kim
Inje University Busan Paik Hospital, Busan, Republic of Korea.
Dong-Soo
DS
Kim
D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000494:pharmacology; D011184:Postoperative Period; D011474:Prosthesis Design; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020123:Sirolimus / Q000031:analogs & derivatives / Q000494:pharmacology; D013997:Time Factors; D016896:Treatment Outcome; D050257:Tubulin Modulators / Q000494:pharmacology
D050257:Tubulin Modulators; C489443:zotarolimus; D017239:Paclitaxel; D020123:Sirolimus