Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy.
We report the case of a 36-year-old woman who developed permanent hypoparathyroidism after thyroidectomy for differentiated thyroid carcinoma. A 6-year follow-up showed an increase of 11% in absolute bone mineral density at the spine and 6% at the hip accompanied by low bone turnover despite thyroid-stimulating hormone suppressive thyroxine therapy.
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerplatz 15, Graz, Austria. karin.amrein@medunigraz.at
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Amrein
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Dimai
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Dobnig
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Fahrleitner-Pammer
D015502:Absorptiometry, Photon; D000328:Adult; D000863:Antacids / Q000627:therapeutic use; D015519:Bone Density / Q000502:physiology*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D016723:Bone Remodeling / Q000502:physiology*; D002117:Calcitriol / Q000627:therapeutic use; D002119:Calcium Carbonate / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging*; D005500:Follow-Up Studies; D006801:Humans; D007011:Hypoparathyroidism / Q000209:etiology*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D017697:Premenopause; D013964:Thyroid Neoplasms / Q000601:surgery; D013965:Thyroidectomy / Q000009:adverse effects*; D013974:Thyroxine / Q000627:therapeutic use
D000863:Antacids; D050071:Bone Density Conservation Agents; D002117:Calcitriol; D002119:Calcium Carbonate; D013974:Thyroxine