Intraoperative MRI and functional mapping.
The integration of functional and anatomical data into neuronavigation is an established standard of care in many neurosurgical departments. Yet, this method has limitations as in most cases the data are acquired prior to surgery. Due to brain-shift the accurate presentation of functional as well as anatomical structures declines in the course of surgery. In consequence, the acquisition of information during surgery about the brain's current functional state is of specific interest. The advancement of imaging technologies (e.g. fMRI, MEG, Intraoperative Optical Intrinsic Signal Imaging--IOIS) and neurophysiological techniques and the advent of intraoperative MRI all had a major impact on neurosurgery. The combination of modalities such as neurophysiology and intraoperative MRI (ioMRI), as well as the acquisition of functional MRI during surgery (ifMRI) are in the focus of this work. Especially the technical aspects and safety issues are elucidated.
Department of Neurosurgery, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany. thomas.gasser@uk-essen.de
Thomas
T
Gasser
Andrea
A
Szelenyi
Christian
C
Senft
Yoshihiro
Y
Muragaki
I Erol
IE
Sandalcioglu
Ulrich
U
Sure
Christopher
C
Nimsky
Volker
V
Seifert
D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery; D004569:Electroencephalography / Q000379:methods; D005260:Female; D005910:Glioma / Q000473:pathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D016343:Monitoring, Intraoperative; D038361:Neuronavigation / Q000379:methods; D019635:Neurosurgical Procedures / Q000379:methods; D010100:Oxygen / Q000097:blood; D019047:Phantoms, Imaging
D010100:Oxygen