Intraoperative spectral domain optical coherence tomography for vitreoretinal surgery.
We demonstrate in vivo human retinal imaging using an intraoperative microscope-mounted optical coherence tomography system (MMOCT). Our optomechanical design adapts an Oculus Binocular Indirect Ophthalmo Microscope (BIOM3), suspended from a Leica ophthalmic surgical microscope, with spectral domain optical coherence tomography (SD-OCT) scanning and relay optics. The MMOCT enables wide-field noncontact real-time cross-sectional imaging of retinal structure, allowing for SD-OCT augmented intrasurgical microscopy for intraocular visualization. We experimentally quantify the axial and lateral resolution of the MMOCT and demonstrate fundus imaging at a 20Hz frame rate.
Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA. yt13@duke.edu
Yuankai K
YK
Tao
Justis P
JP
Ehlers
Cynthia A
CA
Toth
Joseph A
JA
Izatt
D000818:Animals; D006801:Humans; D021621:Imaging, Three-Dimensional; D012160:Retina / Q000033:anatomy & histology*; D042261:Retinoscopes; D013552:Swine; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*; D057586:Vitreoretinal Surgery / Q000295:instrumentation*