[Primitive neuroendocrine cancer of the breast. Post-traumatic discovery of a man].
We report a primitive neuroendocrine breast tumor (NET) in a male. This situation is uncommon by its mode of discovery. We have treated a 74-year-old man with a lesion in the left areola initially considered as an organized hematoma due to a severe trauma. The ablation was performed by direct access under local anesthesia. The analysis of the piece has showed a NET of the breast due to the positivity of the neuroendocrine, cytokeratin and hormone markers. No other NET lesion was found, excluding the secondary origin of the breast tumor. Complementary therapies associated mastectomy, lymphadenectomy, hormonotherapy. Male breast cancer is rare. NET are exceptional, only a dozen of male NET is reported. These tumors affect a specific population and have a better prognosis than infiltrating ductal carcinoma. In our case, no causal link can be demonstrated between trauma and tumor microenvironment necessary for the growth of quiescent cancer cells.
Service de chirurgie plastique, reconstructrice et esthétique, CHU d'Angers, France. dr.potier.benoit@gmail.com
B
B
Potier
D
D
Arnaud
N
N
Paillocher
V
V
Darsonval
P
P
Rousseau
D014408:Biomarkers, Tumor / Q000032:analysis; D001940:Breast / Q000293:injuries* / Q000473:pathology / Q000601:surgery; D018567:Breast Neoplasms, Male / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D003299:Cooperative Behavior; D003937:Diagnosis, Differential; D006406:Hematoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D033162:Incidental Findings; D033183:Interdisciplinary Communication; D008197:Lymph Node Excision; D008297:Male; D008408:Mastectomy; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*
D014408:Biomarkers, Tumor