Intraoperative MRI and functional mapping.
The integration of functional and anatomical data into neuronavigation is an established standard of care in many neurosurgical departments. Yet, this method has limitations as in most cases the data are acquired prior to surgery. Due to brain-shift the accurate presentation of functional as well as anatomical structures declines in the course of surgery. In consequence, the acquisition of information during surgery about the brain's current functional state is of specific interest. The advancement of imaging technologies (e.g. fMRI, MEG, Intraoperative Optical Intrinsic Signal Imaging--IOIS) and neurophysiological techniques and the advent of intraoperative MRI all had a major impact on neurosurgery. The combination of modalities such as neurophysiology and intraoperative MRI (ioMRI), as well as the acquisition of functional MRI during surgery (ifMRI) are in the focus of this work. Especially the technical aspects and safety issues are elucidated.
Gasser
Thomas
T
Department of Neurosurgery, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany. thomas.gasser@uk-essen.de
Szelenyi
Andrea
A
Senft
Christian
C
Muragaki
Yoshihiro
Y
Sandalcioglu
I Erol
IE
Sure
Ulrich
U
Nimsky
Christopher
C
Seifert
Volker
V
D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery; D004569:Electroencephalography / Q000379:methods; D005260:Female; D005910:Glioma / Q000473:pathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D016343:Monitoring, Intraoperative; D038361:Neuronavigation / Q000379:methods; D019635:Neurosurgical Procedures / Q000379:methods; D010100:Oxygen / Q000097:blood; D019047:Phantoms, Imaging
D010100:Oxygen