Genome sequence of the obligate methanotroph Methylosinus trichosporium strain OB3b.
Methylosinus trichosporium OB3b (for "oddball" strain 3b) is an obligate aerobic methane-oxidizing alphaproteobacterium that was originally isolated in 1970 by Roger Whittenbury and colleagues. This strain has since been used extensively to elucidate the structure and function of several key enzymes of methane oxidation, including both particulate and soluble methane monooxygenase (sMMO) and the extracellular copper chelator methanobactin. In particular, the catalytic properties of soluble methane monooxygenase from M. trichosporium OB3b have been well characterized in context with biodegradation of recalcitrant hydrocarbons, such as trichloroethylene. The sequence of the M. trichosporium OB3b genome is the first reported from a member of the Methylocystaceae family in the order Rhizobiales.
Department of Biological Sciences, University of Alberta, CW405 Biological Sciences Centre, Edmonton, Alberta T6G 2E9, Canada. lisa.stein@ualberta.ca
Lisa Y
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Stein
Sukhwan
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Yoon
Jeremy D
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Semrau
Alan A
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Dispirito
Andrew
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Crombie
J Colin
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Murrell
Stéphane
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Vuilleumier
Marina G
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Kalyuzhnaya
Huub J M
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Op den Camp
Françoise
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Bringel
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Bruce
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Cheng
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Copeland
Lynne
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Goodwin
Shunsheng
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Han
Loren
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Hauser
Mike S M
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Jetten
Aurélie
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Lajus
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Land
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Lapidus
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Lucas
Claudine
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Médigue
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Pitluck
Tanja
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Woyke
Ahmet
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Zeytun
Martin G
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Klotz
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology; D016680:Genome, Bacterial; D020602:Methylosinus trichosporium / Q000145:classification* / Q000235:genetics*; D008969:Molecular Sequence Data
D001426:Bacterial Proteins