Acute motor axonal neuropathy in association with Sjögren syndrome.
Sjögren syndrome (SS) has been known to manifest with neurological complications, most frequently of the peripheral nervous system, and often in advance of xerostomia and xerophthalmia. There has been one case report of a patient with SS presenting with acute motor neuropathy similar to Guillain-Barré syndrome (GBS). We report the case of a patient who developed rapidly fulminant acute motor axonal neuropathy (AMAN) with positive anti-GM1 antibody at high titers in association with serological and pathological evidence of SS without xerostomia or xerophthalmia.
Neurological Institute, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44104, USA. ameraldo@gmail.com
Amer
A
Awad
Sani
S
Mathew
Bashar
B
Katirji
D000200:Action Potentials / Q000502:physiology; D000328:Adult; D001369:Axons / Q000473:pathology*; D004568:Electrodiagnosis; D005677:G(M1) Ganglioside / Q000276:immunology / Q000378:metabolism; D006801:Humans; D008297:Male; D009046:Motor Neurons / Q000473:pathology*; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000473:pathology; D011115:Polyneuropathies / Q000473:pathology; D011782:Quadriplegia / Q000209:etiology / Q000503:physiopathology; D012859:Sjogren's Syndrome / Q000473:pathology*
D005677:G(M1) Ganglioside