Coexistence of chronic myeloid leukemia and pulmonary plasmacytoma mimicking primary lung cancer.
A 61-year-old man was diagnosed with the simultaneous occurrence of chronic myeloid leukemia (CML) and infiltrative intrathoracic plasmacytoma, radiologically mimicking bronchogenic carcinoma. Following the administration of imatinib mesylate (IM; 400 mg/day), both hematologic and partial cytogenetic remission of CML were achieved. However, the pulmonary plasmacytoma was persistently aggravated. High-dose dexamethasone was added to the IM therapy because the patient refused radiotherapy to control the aggravated pulmonary plasmacytoma. Finally, he died due to pneumonia and multi-organ failure during concurrent administration of IM and high-dose dexamethasone.
Kim
Hee Jin
HJ
Division of Hematology and Oncology, Department of Internal Medicine, School of Medicine, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Kim
Moon Jin
MJ
Lee
Min Jeong
MJ
Ahn
Jong-Hwa
JH
Kim
Ho-Su
HS
Kim
In-Suk
IS
Lee
Jong Sil
JS
Lee
Gyeong-Won
GW
D002283:Carcinoma, Bronchogenic / Q000175:diagnosis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D015466:Leukemia, Myeloid, Chronic-Phase / Q000175:diagnosis* / Q000188:drug therapy; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000188:drug therapy; D010954:Plasmacytoma / Q000175:diagnosis* / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy