Rapid development of renal failure secondary to AA-type amyloidosis in a patient with polymyalgia rheumatica.
Polymyalgia rheumatica (PMR) is a common chronic inflammatory disorder affecting patients over the age of 50. Renal involvement in PMR is extremely rare and very few cases of AA amyloidosis secondary to PMR have been described in literature. We present a case of a patient with history PMR who developed nephrotic range proteinuria and rapidly deteriorating renal function secondary to AA amyloidosis within 18 months of the onset of symptoms of PMR. This case reinforces the association of PMR with secondary AA amyloidosis and highlights the importance of monitoring renal function in patients with PMR.
Department of Nephrology, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK. mmjavaid@doctors.org.uk
Muhammad Masoom
MM
Javaid
Manivarma
M
Kamalanathan
Sui Phin
SP
Kon
D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D005260:Female; D006801:Humans; D011111:Polymyalgia Rheumatica / Q000150:complications*; D051437:Renal Insufficiency / Q000209:etiology*