Ultradian metabolic cycles in yeast.
Budding yeast are capable of displaying various modes of oscillatory behavior. Such cycles can occur with a period ranging from 1 min up to many hours, depending on the growth and culturing conditions used to observe them. This chapter discusses the robust oscillations in oxygen consumption exhibited by high-density yeast cell populations during continuous, glucose-limited growth in a chemostat. These ultradian metabolic cycles offer a view of the life of yeast cells under a challenging, nutrient-poor growth environment and might represent useful systems to interrogate a variety of fundamental metabolic and regulatory processes.
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Benjamin P
BP
Tu
D000204:Activity Cycles / Q000235:genetics / Q000502:physiology*; D010101:Oxygen Consumption / Q000235:genetics / Q000502:physiology; D015003:Yeasts / Q000235:genetics / Q000378:metabolism*