Mass spectrometry and renal calculi.
The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.
"Carol Davila" Hospital of Nephrology, 4 Calea Grivitei Street, RO-010701 Bucharest, Romania.
Mircea
M
Penescu
Victor Lorin
VL
Purcarea
Ioana
I
Sisu
Eugen
E
Sisu
D000818:Animals; D002129:Calcium Oxalate / Q000032:analysis / Q000652:urine; D002853:Chromatography, Liquid / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D005506:Food Contamination / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry* / Q000652:urine; D013058:Mass Spectrometry / Q000379:methods*; D053495:Osteopontin / Q000652:urine; D020543:Proteome / Q000032:analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D053719:Tandem Mass Spectrometry / Q000379:methods; D014227:Triazines / Q000633:toxicity / Q000652:urine
D020543:Proteome; D014227:Triazines; D053495:Osteopontin; D002129:Calcium Oxalate; C011907:melamine