Subcutaneous phaeohyphomycosis due to Exophiala spinifera in an immunocompromised host.
A case of phaeohyphomycosis presenting as multiple subcutaneous abscesses in a young lady with deteriorating liver function was reported here. The lesion started as a solitary abscess in the neck, mimicking tuberculous cold abscess and rapidly involved the face, chest, arms, and legs within six months with ulceration and discharge of thick brownish foul smelling pus. Potassium hydroxide mount of pus from various sites revealed septate dematiaceous hyphae and pseudohyphae. Culture yielded pure growth of Exophiala spinifera. Tissue debridement was done along with initiation of antifungal therapy with ketoconazole. As liver function deteriorated, antifungal therapy was withdrawn after seven days. Patient expired three weeks after admission due to hepatic failure.
Radhakrishnan
Deepa
D
Institute of Microbiology, Madras Medical College and Government General Hospital, Chennai, India. deeparsn@yahoo.co.in
Jayalakshmi
G
G
Madhumathy
A
A
Banu
S Thasneem
ST
Geethalakshmi
S
S
Sumathi
G
G
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D005093:Exophiala / Q000145:classification / Q000302:isolation & purification*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D040521:Subcutaneous Tissue / Q000382:microbiology* / Q000473:pathology; D055815:Young Adult
D000935:Antifungal Agents