title: [Effects of positive end expiratory pressure on pulmonary surfactant in patients undergoing one-lung ventilation].
abstract: OBJECTIVE
  To evaluate the effect of positive end expiratory pressure on the bronchoalveolar lavage fluid (BALF) in pulmonary surfactant (PS) of patient during one lung ventilation anesthesia.
  
  
  METHODS
  Patients undergoing Bullae resection were anesthetized with treatment (n = 12) or control (n = 12) combined anesthesia. Total phospholipid (TPL), saturated phosphatidylcholine (SatPC) and total protein (TP) in the bronchoalveolar lavage fluid (BALF) were measure. The ratio of SatPC/TPL% and SatPC/TP% represented the activity of PS.
  
  
  RESULTS
  The thoracic surgery pulmonary surfactant significantly reduced, PEEP can prevent the decrease, but with decreased cardiac output.
  
  
  CONCLUSIONS
  The end-expiratory pressure breathing can maintain the level of pulmonary surfactant to protect lung function.
authors.affiliation: Department of Anesthesiology, Zhoushan Hospital Zhoushan, Zhoushan 316000, China. lmz1016@126.com
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Bao-bin
authors.initials: BB
authors.lastname: Gao
authors.forename: Hai-qing
authors.initials: HQ
authors.lastname: Fu
authors.forename: Jiang-hong
authors.initials: JH
authors.lastname: Deng
mesh_terms: D000293:Adolescent; D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis; D011175:Positive-Pressure Respiration; D011506:Proteins / Q000032:analysis; D011663:Pulmonary Surfactants / Q000378:metabolism*; D055815:Young Adult
chemical_list: D010713:Phosphatidylcholines; D010743:Phospholipids; D011506:Proteins; D011663:Pulmonary Surfactants