Apparent renal disease due to elevated creatinine levels associated with the use of boldenone.
The widespread use of reporting estimated glomerular filtration rate (eGFR) alongside serum creatinine has led to a heightened appreciation of renal disease. However, creatinine is recognized as an insensitive marker of true GFR and therefore can lead to misdiagnosis of renal dysfunction in the absence of true pathology. We report the case of a 37-year-old male referred due to abnormal eGFR and creatinine in the absence of clinical signs, symptoms or other biochemical abnormalities of renal disease. Subsequent investigations based on a high index of suspicion for exogenous substance abuse led to a novel observation of significantly raised creatinine due to the presence of boldenone, an equine anabolic steroid commonly abused in body building.
Winnett
Georgia
G
Renal Medicine, Southend University Hospital NHS Trust, Westcliff on Sea, Essex, UK.
Cranfield
Lesley
L
Almond
Michael
M
D000328:Adult; D045930:Anabolic Agents / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood*; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced*; D008297:Male; D013739:Testosterone / Q000009:adverse effects / Q000031:analogs & derivatives*
D045930:Anabolic Agents; D013739:Testosterone; C013915:boldenone; D003404:Creatinine