title: Application of manuka honey and GENADYNE A4 negative pressure wound therapy system in a 55-year-old woman with extensive phlegmonous and necrotic lesions in the abdominal integuments and lumbar region after traumatic rupture of the colon.
abstract: BACKGROUND
  Antibiotic resistance of bacteria is on the rise and thus, the discovery of alternative therapeutic agents is urgently needed. Honey possesses good therapeutic potential, including wound healing properties and antimicrobial activity.
  
  
  METHODS
  The authors report on the case of a 55-year-old woman with extensive phlegmonous and necrotic lesions of the abdominal integuments and the lumbar area following traumatic colonic rupture, treated with Manuka honey wound dressings and the GENADYNE A4 negative pressure wound healing system.
  
  
  CONCLUSIONS
  The application of the Manuka honey and the GENADYNE A4 negative pressure wound healing system in treating phlegmonous lesions of the abdominal integuments after rupture of the colon brought good effects, ultimately enabling skin autografting on the wound site and complete wound healing.
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, Military Medical Academy University Hospital in Lodz, Lodz, Poland.
authors.forename: Alina
authors.initials: A
authors.lastname: Rudzka-Nowak
authors.forename: Paweł
authors.initials: P
authors.lastname: Łuczywek
authors.forename: Maciej Jerzy
authors.initials: MJ
authors.lastname: Gajos
authors.forename: Mariusz
authors.initials: M
authors.lastname: Piechota
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use; D003106:Colon / Q000293:injuries / Q000382:microbiology / Q000473:pathology; D005260:Female; D006722:Honey; D006801:Humans; D031649:Leptospermum / Q000737:chemistry*; D008875:Middle Aged; D009336:Necrosis / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D012421:Rupture; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents