title: [Relationship of motor deficits and imaging features in metastatic epidural spinal cord compression].
abstract: OBJECTIVE
  To explore the relationship of motor deficits of the lower extremities with the imaging features of malignant spinal cord compression (MESCCs).
  
  
  METHODS
  From July 2006 through December 2008, 56 successive MESCC patients were treated at our department. All were evaluated by magnetic resonance imaging and computed tomography and were scored according to motor deficits Frankel grading on admission. Imaging assessment factors of main involved vertebrae were level of vertebral metastatic location, epidural space involvement, vertebral body involvement, lamina involvement, posterior protrusion of posterior wall, pedicle involvement, continuity of main involved vertebrae, fracture of anterior column, fracture of posterior wall, location in upper thoracic spine and/or cervicothoracic junction.
  
  
  RESULTS
  Occurrence was the same between paralytic state of MESCCs and epidural space involvement of imaging features. Multiple regression equation showed that paralytic state had a linear regression relationship with imaging factors of lamina involvement (X1), posterior protrusion of posterior wall (X2), location in upper thoracic spine and/or cervicothoracic junction (X7) of main involved vertebrae. The optimal regression equation of paralytic state (Y) and imaging feature (X) was Y = -0.009 +0.639X, + 0.149X, +0.282X. Lamina involvement of main involved vertebrae has a greatest influence upon paralytic state of MESCC patients.
  
  
  CONCLUSIONS
  Imaging factors of lamina involvement, posterior protrusion of posterior wall, location in upper thoracic spine and/or cervicothoracic junction of main involved vertebrae can predict the paralytic state of MESCC patients. MESCC with lamina involvement is more easily encroached on epidural space.
authors.affiliation: Department of Orthopedic Surgery, PLA 307th Hospital, Beijing 100071, China.
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Liu
authors.forename: Yao-Sheng
authors.initials: YS
authors.lastname: Liu
authors.forename: Ding-Feng
authors.initials: DF
authors.lastname: Li
authors.forename: Hai-Tao
authors.initials: HT
authors.lastname: Fan
authors.forename: Jian-Ye
authors.initials: JY
authors.lastname: Huai
authors.forename: Jun
authors.initials: J
authors.lastname: Guo
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Cheng
authors.initials: C
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Qiu
authors.initials: Q
authors.lastname: Cui
authors.forename: Wei-Hao
authors.initials: WH
authors.lastname: Jiang
authors.forename: Yun-Cen
authors.initials: YC
authors.lastname: Cao
authors.forename: Ning
authors.initials: N
authors.lastname: Jiang
authors.forename: Jia-Hong
authors.initials: JH
authors.lastname: Sui
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Jiu
authors.initials: J
authors.lastname: Zhou
mesh_terms: D015174:Epidural Neoplasms / Q000473:pathology* / Q000503:physiopathology* / Q000556:secondary; D006801:Humans; D009069:Movement Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D013117:Spinal Cord Compression / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*