title: [Multivariate analysis of recurrence factors for non muscle-invasive bladder urothelial carcinomas].
abstract: OBJECTIVE
  To discuss the risk factors of recurrent non-muscle-invasive bladder cancer and elucidate its clinical significance.
  
  
  METHODS
  The retrospective survival analysis of 161 patients with non-muscle-invasive bladder cancer was performed by Kaplan-Meier method, Log-rank test and COX proportional hazard model.
  
  
  RESULTS
  On univariate analysis, the parameters of tumor stage, tumor grade, number of tumors and previous recurrence were significant for tumor recurrence (all P < 0.05). On multivariate analysis of COX proportional hazard model, all the above risk factors remained significant for tumor recurrence. The hazard ratios were as follows: tumor stage (RR = 3.810, P = 0.001), tumor grade (RR = 2.416, P = 0.009), number of tumors (RR = 1.736, P = 0.036) and previous recurrence (RR = 1.810, P = 0.010).
  
  
  CONCLUSIONS
  Tumor stage and tumor grade plays the most important role in tumor recurrence.
authors.affiliation: Department of Urology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. junxingchen@hotmail.com
authors.forename: Jun-xing
authors.initials: JX
authors.lastname: Chen
authors.forename: Nan
authors.initials: N
authors.lastname: Deng
authors.forename: Ling-wu
authors.initials: LW
authors.lastname: Chen
authors.forename: Shao-peng
authors.initials: SP
authors.lastname: Qiu
authors.forename: Xiao-fei
authors.initials: XF
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Yu-ping
authors.initials: YP
authors.lastname: Dai
authors.forename: Yue-you
authors.initials: YY
authors.lastname: Liang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology* / Q000473:pathology*