title: Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version 2 test using the TaqMan 48 analyzer and the Abbott RealTime HIV-1 assay.
abstract: Acceptable precision was achieved in a comparison study of the Abbott RealTime (RT) and Roche CAP/CTM-48 V2 HIV-1 assays, but viral load quantification was under- and overestimated, respectively, compared to the 2nd HIV-1 WHO International Standard. The same quantification patterns were observed for patient cohorts from Africa and the United States.
authors.affiliation: Quintiles Global Central Laboratories, The Alba Campus, Rosebank, Livingston EH54 7EG, United Kingdom. Estrelita.JanseVanRensburg@quintiles.com
authors.forename: Estrelita Janse
authors.initials: EJ
authors.lastname: van Rensburg
authors.forename: Karen
authors.initials: K
authors.lastname: Tait
authors.forename: Alistair
authors.initials: A
authors.lastname: Watt
authors.forename: Robert
authors.initials: R
authors.lastname: Schall
mesh_terms: D000349:Africa; D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D014481:United States; D019562:Viral Load / Q000379:methods*
chemical_list: D011933:Reagent Kits, Diagnostic