Safety and immunogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine coadministered with DTPw-HBV/Hib and poliovirus vaccines.
The safety and reactogenicity profiles of the 10-valent pneumococcal conjugate vaccine, PHiD-CV, and 7vCRM were comparable within the Philippines and Poland when coadministered as a booster dose with DTPw-HBV/Hib and poliovirus vaccines to toddlers primed with the same vaccines. Robust immune responses for all 10 vaccine pneumococcal serotypes and protein D following PHiD-CV booster vaccination were indicative of effective priming.
Bermal
Nancy
N
Research Institute for Tropical Medicine, Filinvest Corporate City, Alabang, Muntinlupa City, Philippines. nnbid02@yahoo.com
Szenborn
Leszek
L
Edison
Alberto
A
Hernandez
Marina
M
Pejcz
Jerzy
J
Majda-Stanislawska
Ewa
E
Gatchalian
Salvacion
S
Fanic
Aurélie
A
Dieussaert
Ilse
I
Schuerman
Lode
L
D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage* / Q000009:adverse effects*; D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007117:Immunization, Secondary; D007223:Infant; D022242:Pneumococcal Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage*; D017778:Vaccines, Combined / Q000008:administration & dosage; D018074:Vaccines, Conjugate / Q000008:administration & dosage / Q000009:adverse effects
C538863:10-valent pneumococcal vaccine; C451839:DTPa-HBV-IPV combined vaccine; D015721:Diphtheria-Tetanus-Pertussis Vaccine; C524361:DtwP-HepB-Hib vaccine; D018073:Haemophilus Vaccines; D017325:Hepatitis B Vaccines; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022242:Pneumococcal Vaccines; D011054:Poliovirus Vaccine, Inactivated; D017778:Vaccines, Combined; D018074:Vaccines, Conjugate