Trans-centromere effects on meiotic recombination in the zebrafish.
We report that lack of crossover along one chromosome arm is associated with high-frequency occurrence of recombination close to the opposing arm's centromere during zebrafish meiotic recombination. Our data indicate that recombination behavior on the two arms of a chromosome is linked. These results inform mapping strategies for telomeric mutants.
Demarest
Bradley L
BL
Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA.
Horsley
Wyatt H
WH
Locke
Erin E
EE
Boucher
Kenneth
K
Grunwald
David J
DJ
Trede
Nikolaus S
NS
D000818:Animals; D002503:Centromere / Q000235:genetics*; D002842:Chromatids / Q000235:genetics; D005260:Female; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D008540:Meiosis / Q000235:genetics*; D009154:Mutation; D010641:Phenotype; D011995:Recombination, Genetic / Q000235:genetics*; D016615:Telomere / Q000235:genetics; D015027:Zebrafish / Q000235:genetics*