title: Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer: a pilot study.
abstract: OBJECTIVE
  Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study.
  
  
  METHODS
  MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle.
  
  
  RESULTS
  Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes.
  
  
  CONCLUSIONS
  Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, Kyushu Koseinenkin Hospital, 1-8-1 Kishinoura, Nishiku, Kitakyushu, Japan. muneyuki.masuda@qkn-hosp.jp
authors.forename: Muneyuki
authors.initials: M
authors.lastname: Masuda
authors.forename: Junichi
authors.initials: J
authors.lastname: Fukushima
authors.forename: Hideki
authors.initials: H
authors.lastname: Kadota
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kamizono
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Ejima
authors.forename: Masahiko
authors.initials: M
authors.lastname: Taura
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009367:Neoplasm Staging; D009959:Oropharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D009960:Oropharynx / Q000473:pathology / Q000601:surgery*; D010611:Pharyngectomy / Q000379:methods*; D010865:Pilot Projects; D011183:Postoperative Complications / Q000209:etiology; D019291:Skull Base / Q000601:surgery; D016896:Treatment Outcome