title: Initial results of a 12-week, institution-based, supervised exercise rehabilitation program for the management of peripheral arterial disease.
abstract: This study assessed the effectiveness of a 12-week, institution-based, supervised exercise rehabilitation program with atherogenic risk factor modification in improving cardiovascular profile, ambulatory function, and quality of life of patients with peripheral arterial disease (PAD) by comparing pre- and postprogram measurements. Participants were prospectively enrolled. Cardiovascular profile variables, ambulatory function tests, and quality of life questionnaires were evaluated. Of 101 institution-based program participants, 69 completed the 12-session minimum and 47 completed a postprogram evaluation. Mean postprogram results were significantly different from preprogram results, corresponding to improvement, for the following variables: triglyceride levels (p  =  .036), both function tests (p < .001 for both), four of five Walking Impairment Questionnaire measurements, and Intermittent Claudication Questionnaire score (p  = .001). This supervised exercise program improved the cardiovascular profiles, ambulatory function, and quality of life of PAD patients completing the program and is a viable adjunct to drug therapy and surgical intervention.
authors.affiliation: Grant Medical Center, Columbus, OH, USA. rfranz2@ohiohealth.com
authors.forename: Randall W
authors.initials: RW
authors.lastname: Franz
authors.forename: Tammy
authors.initials: T
authors.lastname: Garwick
authors.forename: Katie
authors.initials: K
authors.lastname: Haldeman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D055109:Ankle Brachial Index; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005080:Exercise Test; D005081:Exercise Therapy; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009820:Ohio; D058729:Peripheral Arterial Disease / Q000150:complications / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D011446:Prospective Studies; D011788:Quality of Life; D020127:Recovery of Function; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D016138:Walking
chemical_list: D002317:Cardiovascular Agents; D008055:Lipids