[Multivariate analysis of recurrence factors for non muscle-invasive bladder urothelial carcinomas].
OBJECTIVE
To discuss the risk factors of recurrent non-muscle-invasive bladder cancer and elucidate its clinical significance.


METHODS
The retrospective survival analysis of 161 patients with non-muscle-invasive bladder cancer was performed by Kaplan-Meier method, Log-rank test and COX proportional hazard model.


RESULTS
On univariate analysis, the parameters of tumor stage, tumor grade, number of tumors and previous recurrence were significant for tumor recurrence (all P < 0.05). On multivariate analysis of COX proportional hazard model, all the above risk factors remained significant for tumor recurrence. The hazard ratios were as follows: tumor stage (RR = 3.810, P = 0.001), tumor grade (RR = 2.416, P = 0.009), number of tumors (RR = 1.736, P = 0.036) and previous recurrence (RR = 1.810, P = 0.010).


CONCLUSIONS
Tumor stage and tumor grade plays the most important role in tumor recurrence.
Chen
Jun-xing
JX
Department of Urology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. junxingchen@hotmail.com
Deng
Nan
N
Chen
Ling-wu
LW
Qiu
Shao-peng
SP
Li
Xiao-fei
XF
Chen
Wei
W
Dai
Yu-ping
YP
Liang
Yue-you
YY
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology* / Q000473:pathology*