[Expression of angiogenesis labelled by anti-CD34 monoclonal antibody in non-small cell lung cancer].
BACKGROUND
To determine the expression of angiogenesis labelled by anti-CD34 monoclonal antibody in non-small cell lung cancer.


METHODS
Immunohistochemical detection for tumor-associated microvessels was performed to 81 non-small cell lung cancer tissues using anti-CD34 monoclonal antibodies directed against endothelial markers.


RESULTS
Staining of CD34 was easy to identify because of its specificity,sensitivity and clear background.Statistic analysis showed that the microvessel count was significantly related to the TNM staging but not to lymph node metastasis and other clinicopathologic characteristics.


CONCLUSIONS
MVD may play an important role in the oncogenesis and development of lung cancer.
Zhu
B
B
Department of Thoracic Surgery,The First Hospital,Chongqing University of Medical Science,Chongqing 400016,P.R.China.
Wen
J
J