title: The presigmoid approach for removal of tumours causing ventral compression of the brainstem. Surgical results and postoperative quality of life.
abstract: OBJECTIVE
  To assess surgical results and quality of life after removal of tumours causing ventral compression of the brainstem using the presigmoid or combined presigmoid/retrosigmoid approaches.
  
  
  METHODS
  A review of all our patients operated on with removal of tumours causing ventral compression of the brainstem in whom either the presigmoid or combined presigmoid/retrosigmoid approaches were used. Post-operative quality of life was assessed using the SF-36 questionnaire.
  
  
  RESULTS
  A total of 12 consecutive patients were included. A favourable complication profile was found. Cerebrospinal fluid leakage and secondary hydrocephalus were the most frequent complications. Post-operative scores from Karnofsky Performance Scale and ECOG after median 24 months were median 85 and 1, respectively, representing ability to carry on daily activities. Nevertheless, quality of life as assessed subjectively by SF-36 showed significantly reduced values as compared with normative values from Norwegian population.
  
  
  CONCLUSIONS
  We found favourable surgical results when using the presigmoid approach alone or combined with the retrosigmoid route for large-sized extrinsic tumours causing ventral compression of the brainstem, both regarding complication profile, degree of tumour removal and functional outcome. However, impact of disease and surgery on quality of life appears to be more significant when assessed subjectively by the patients.
authors.affiliation: Department of Neurosurgery, Oslo University Hospital--Rikshospitalet, Oslo, Norway. radek.fric@rikshospitalet.no
authors.forename: Radek
authors.initials: R
authors.lastname: Frič
authors.forename: Per Kristian
authors.initials: PK
authors.lastname: Eide
mesh_terms: D000328:Adult; D000368:Aged; D001933:Brain Stem; D003251:Constriction, Pathologic / Q000150:complications / Q000601:surgery; D019299:Decompression, Surgical / Q000379:methods*; D005260:Female; D006801:Humans; D015192:Infratentorial Neoplasms / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology; D011184:Postoperative Period; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome