Emergence of a unique penicillin-resistant Streptococcus pneumoniae serogroup 35 strain.
We analyzed seven Streptococcus pneumoniae serogroup 35 isolates by pulsed-field gel electrophoresis of the genome and pbp2b gene nucleotide sequences. Three penicillin-susceptible strains and one penicillin-intermediate-resistant strain exhibited 100% identity to prototype R6. Two resistant strains and one other intermediate strain differed from them and contained a unique sequence.
Stanek
Ronald J
RJ
Department of Medicine, Marshall University, Joan C. Edwards School of Medicine, Byrd Clinical Center, 1249 15th Street, Huntington, WV 25701, USA.
Maher
Mary B
MB
Norton
Nancy B
NB
Mufson
Maurice A
MA
D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D058889:Molecular Typing; D010403:Penicillin Resistance; D046915:Penicillin-Binding Proteins / Q000235:genetics; D011008:Pneumococcal Infections / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*
D001426:Bacterial Proteins; D046915:Penicillin-Binding Proteins