title: Primary carcinoid tumor of the frontal sinus: A case report.
abstract: Carcinoid tumors are rare, indolent, neuroendocrine tumors that are most commonly found in the gastrointestinal tract and lungs. They occasionally develop in the head and neck, either as a primary tumor or, more commonly, as a metastasis. The most common sites of head and neck carcinoids are the larynx and middle ear. Only a few cases of carcinoid in the nasal cavity and paranasal sinuses have been reported. We describe a case of primary typical carcinoid of the frontal sinus in a 61-year-old man, and we review the clinical, imaging, surgical, and histochemical findings in this case. The patient was treated with endoscopic resection. A subsequent workup for metastatic and occult primary disease was negative, confirming that the frontal sinus was the primary source. At follow-up 12 months postoperatively, the patient remained without disease. To the best of our knowledge, this is the first report of a primary typical carcinoid tumor originating in the frontal sinus.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
authors.forename: Michael W
authors.initials: MW
authors.lastname: Chu
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Karakla
authors.forename: Marc
authors.initials: M
authors.lastname: Silverberg
authors.forename: Joseph K
authors.initials: JK
authors.lastname: Han
mesh_terms: D002276:Carcinoid Tumor / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D004724:Endoscopy; D005626:Frontal Sinus / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed