Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury.
He
Weichun
W
Department of Pathology, University of Pittsburgh School of Medicine, S-405 Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15261, USA.
Kang
Young Sun
YS
Dai
Chunsun
C
Liu
Youhua
Y
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D000818:Animals; D004195:Disease Models, Animal; D004317:Doxorubicin / Q000009:adverse effects; D004872:Ergocalciferols / Q000494:pharmacology*; D005920:Glomerular Mesangium / Q000187:drug effects / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D050199:Podocytes / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D011507:Proteinuria / Q000517:prevention & control*; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D014807:Vitamin D / Q000031:analogs & derivatives*; D051153:Wnt Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D051176:beta Catenin / Q000037:antagonists & inhibitors* / Q000378:metabolism
D004872:Ergocalciferols; D051153:Wnt Proteins; D051176:beta Catenin; D014807:Vitamin D; C084656:paricalcitol; D004317:Doxorubicin