Shikonin inhibits tumor invasion via down-regulation of NF-κB-mediated MMP-9 expression in human ACC-M cells.
Min
R
R
Department of Oral & Maxillofacial Surgery, Affiliated No. 9 People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zun
Z
Z
Min
Y
Y
Wenhu
D
D
Wenjun
Y
Y
Chenping
Z
Z
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D015153:Blotting, Western; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology* / Q000503:physiopathology; D018929:Cell Culture Techniques; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004396:Coloring Agents; D004305:Dose-Response Relationship, Drug; D015536:Down-Regulation; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D020672:I-kappa B Proteins / Q000187:drug effects; D020778:Matrix Metalloproteinase 2 / Q000187:drug effects; D020780:Matrix Metalloproteinase 9 / Q000187:drug effects*; D016328:NF-kappa B / Q000187:drug effects*; D009285:Naphthoquinones / Q000008:administration & dosage / Q000494:pharmacology*; D009361:Neoplasm Invasiveness / Q000473:pathology / Q000503:physiopathology; D013778:Tetrazolium Salts; D013844:Thiazoles; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects
D000970:Antineoplastic Agents; D004396:Coloring Agents; D004365:Drugs, Chinese Herbal; D020672:I-kappa B Proteins; D016328:NF-kappa B; D009285:Naphthoquinones; D013778:Tetrazolium Salts; D013844:Thiazoles; D014409:Tumor Necrosis Factor-alpha; C016101:shikonin; C522361:MMP2 protein, human; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9; C022616:thiazolyl blue