EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation.
Margolis
Seth S
SS
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Salogiannis
John
J
Lipton
David M
DM
Mandel-Brehm
Caleigh
C
Wills
Zachary P
ZP
Mardinly
Alan R
AR
Hu
Linda
L
Greer
Paul L
PL
Bikoff
Jay B
JB
Ho
Hsin-Yi Henry
HY
Soskis
Michael J
MJ
Sahin
Mustafa
M
Greenberg
Michael E
ME
D017204:Angelman Syndrome / Q000378:metabolism; D000818:Animals; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000378:metabolism; D018891:Dentate Gyrus / Q000166:cytology / Q000378:metabolism; D004622:Embryo, Mammalian / Q000378:metabolism; D055786:Gene Knockout Techniques; D006801:Humans; D051379:Mice; D051381:Rats; D020318:Rats, Long-Evans; D036081:Receptors, Eph Family / Q000235:genetics; D013569:Synapses / Q000378:metabolism*; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism; D020742:rhoA GTP-Binding Protein / Q000235:genetics / Q000378:metabolism*
D044767:Ubiquitin-Protein Ligases; D036081:Receptors, Eph Family; D020742:rhoA GTP-Binding Protein