title: Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases.
authors.affiliation: Department of Biology, Brandeis University, 415 South Street, Waltham, MA 02454-9110, USA.
authors.forename: Deviprasad R
authors.initials: DR
authors.lastname: Gollapalli
authors.forename: Iain S
authors.initials: IS
authors.lastname: Macpherson
authors.forename: George
authors.initials: G
authors.lastname: Liechti
authors.forename: Suresh Kumar
authors.initials: SK
authors.lastname: Gorla
authors.forename: Joanna B
authors.initials: JB
authors.lastname: Goldberg
authors.forename: Lizbeth
authors.initials: L
authors.lastname: Hedstrom
mesh_terms: D001665:Binding Sites; D025065:Borrelia burgdorferi / Q000187:drug effects / Q000201:enzymology; D003198:Computer Simulation; D016785:Cryptosporidium parvum / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors* / Q000145:classification / Q000378:metabolism; D007700:Kinetics; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D013297:Streptococcus pyogenes / Q000187:drug effects / Q000201:enzymology
chemical_list: D004791:Enzyme Inhibitors; D011994:Recombinant Proteins; D007168:IMP Dehydrogenase