Characterization, synthesis and self-aggregation of (-)-alternarlactam: a new fungal cytotoxin with cyclopentenone and isoquinolinone scaffolds.
Zhang
Ai Hua
AH
Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
Jiang
Nan
N
Gu
Wen
W
Ma
Jing
J
Wang
Yu Rong
YR
Song
Yong Chun
YC
Tan
Ren Xiang
RX
D000528:Alternaria / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D031255:Carex Plant / Q000382:microbiology; D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003603:Cytotoxins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004317:Doxorubicin / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006367:HeLa Cells; D006801:Humans; D007546:Isoquinolines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013237:Stereoisomerism
D000970:Antineoplastic Agents; D003517:Cyclopentanes; D003603:Cytotoxins; D007546:Isoquinolines; C557006:alternarlactam; D004317:Doxorubicin; C013905:cyclopentenone