title: Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes.
authors.affiliation: Heart Centre, Children's Hospital of Chongqing Medical University, Chongqing, PR China.
authors.forename: Huichao
authors.initials: H
authors.lastname: Sun
authors.forename: Xuefang
authors.initials: X
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Zhu
authors.forename: Tiewei
authors.initials: T
authors.lastname: Lv
authors.forename: Yuan
authors.initials: Y
authors.lastname: Chen
authors.forename: Guozhen
authors.initials: G
authors.lastname: Chen
authors.forename: Lilin
authors.initials: L
authors.lastname: Zhong
authors.forename: Yasha
authors.initials: Y
authors.lastname: Li
authors.forename: Xupei
authors.initials: X
authors.lastname: Huang
authors.forename: Guoying
authors.initials: G
authors.lastname: Huang
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
mesh_terms: D000107:Acetylation / Q000187:drug effects; D000818:Animals; D000831:Animals, Newborn; D015153:Blotting, Western; D047369:Chromatin Immunoprecipitation; D003474:Curcumin / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D015536:Down-Regulation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004797:Enzyme-Linked Immunosorbent Assay; D044127:Epigenesis, Genetic; D006657:Histones / Q000187:drug effects* / Q000378:metabolism; D051379:Mice; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism; D011401:Promoter Regions, Genetic; D020133:Reverse Transcriptase Polymerase Chain Reaction; D050880:p300-CBP Transcription Factors / Q000037:antagonists & inhibitors*; D000099224:p300-CBP-Associated Factor
chemical_list: D003474:Curcumin; D004791:Enzyme Inhibitors; D006657:Histones; D050880:p300-CBP Transcription Factors; D000099224:p300-CBP-Associated Factor