title: Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase.
authors.affiliation: Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Sandra B
authors.initials: SB
authors.lastname: Gabelli
authors.forename: Krisna C
authors.initials: KC
authors.lastname: Duong-Ly
authors.forename: Evan T
authors.initials: ET
authors.lastname: Brower
authors.forename: L Mario
authors.initials: LM
authors.lastname: Amzel
mesh_terms: D005838:Genotype; D006801:Humans; D008958:Models, Molecular; D009154:Mutation; D009369:Neoplasms / Q000201:enzymology* / Q000235:genetics*; D010455:Peptides / Q000235:genetics / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000737:chemistry / Q000235:genetics; D000081082:Phosphoinositide-3 Kinase Inhibitors; D011485:Protein Binding; D011487:Protein Conformation; D047428:Protein Kinase Inhibitors / Q000378:metabolism*; D021122:Protein Subunits / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D010455:Peptides; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D047428:Protein Kinase Inhibitors; D021122:Protein Subunits