High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.
Birse
Ryan T
RT
NASCR Center, Sanford/Burnham Medical Research Institute, La Jolla, CA 92037, USA.
Choi
Joan
J
Reardon
Kathryn
K
Rodriguez
Jessica
J
Graham
Suzanne
S
Diop
Soda
S
Ocorr
Karen
K
Bodmer
Rolf
R
Oldham
Sean
S
D000818:Animals; D004041:Dietary Fats / Q000009:adverse effects*; D004330:Drosophila / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D006321:Heart / Q000503:physiopathology; D006331:Heart Diseases / Q000150:complications / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008659:Metabolic Diseases / Q000235:genetics; D009154:Mutation; D009765:Obesity / Q000150:complications / Q000209:etiology* / Q000378:metabolism; D010641:Phenotype; D015398:Signal Transduction; D058570:TOR Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism
D004041:Dietary Fats; D029721:Drosophila Proteins; D007328:Insulin; D014280:Triglycerides; D058570:TOR Serine-Threonine Kinases