Improved anti-tumor activity of stabilized anthracycline polymeric micelle formulation, NC-6300.
Harada
Mitsunori
M
Research Division, NanoCarrier Co., Ltd, Chiba, Japan. harada@nanocarrier.co.jp
Bobe
Iulian
I
Saito
Hiroyuki
H
Shibata
Naoya
N
Tanaka
Ryosuke
R
Hayashi
Tatsuyuki
T
Kato
Yasuki
Y
D000818:Animals; D018943:Anthracyclines / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D015251:Epirubicin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000633:toxicity; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008823:Micelles; D011506:Proteins / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D017208:Rats, Wistar; D023041:Xenograft Model Antitumor Assays
D018943:Anthracyclines; D000970:Antineoplastic Agents; D008823:Micelles; C555062:NC 6300; D011506:Proteins; D015251:Epirubicin