title: Discovery and selectivity-profiling of 4-benzylamino 1-aza-9-oxafluorene derivatives as lead structures for IGF-1R inhibitors.
authors.affiliation: Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Krug
authors.forename: German
authors.initials: G
authors.lastname: Erlenkamp
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Sippl
authors.forename: Christoph
authors.initials: C
authors.lastname: Schächtele
authors.forename: Frank
authors.initials: F
authors.lastname: Totzke
authors.forename: Andreas
authors.initials: A
authors.lastname: Hilgeroth
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001596:Benzylamines / Q000138:chemical synthesis / Q000494:pharmacology*; D045744:Cell Line, Tumor; D003198:Computer Simulation; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D011485:Protein Binding; D020794:Receptor Protein-Tyrosine Kinases / Q000737:chemistry; D017526:Receptor, IGF Type 1 / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D001596:Benzylamines; D020794:Receptor Protein-Tyrosine Kinases; D017526:Receptor, IGF Type 1