title: Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
authors.affiliation: Department of Colorectal Surgery, the Affiliated Tumor Hospital, Harbin Medical University, Harbin, China.
authors.forename: Yan Long
authors.initials: YL
authors.lastname: Liu
authors.forename: Yan Mei
authors.initials: YM
authors.lastname: Yang
authors.forename: Hui
authors.initials: H
authors.lastname: Xu
authors.forename: Xin Shu
authors.initials: XS
authors.lastname: Dong
mesh_terms: D002277:Carcinoma / Q000201:enzymology* / Q000235:genetics / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000201:enzymology* / Q000235:genetics / Q000601:surgery*; D018450:Disease Progression; D018572:Disease-Free Survival; D010450:Endopeptidases / Q000235:genetics / Q000378:metabolism*; D005260:Female; D015870:Gene Expression; D016259:Genes, myc / Q000235:genetics; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D009687:Nuclear Proteins / Q000235:genetics; D063150:Polycomb Repressive Complex 1; D011379:Prognosis; D016016:Proportional Hazards Models; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000235:genetics; D013869:Thiolester Hydrolases / Q000235:genetics / Q000378:metabolism*; D017211:Treatment Failure; D043222:Ubiquitin Thiolesterase; D064570:Ubiquitin-Specific Proteases; D015854:Up-Regulation
chemical_list: C069077:BMI1 protein, human; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D012333:RNA, Messenger; D012097:Repressor Proteins; D063150:Polycomb Repressive Complex 1; D013869:Thiolester Hydrolases; D010450:Endopeptidases; D043222:Ubiquitin Thiolesterase; D064570:Ubiquitin-Specific Proteases; C527170:Usp22 protein, human