Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.
Zou
Yao
Y
Alberta Ingenuity Centre for Carbohydrate Science, Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada.
Albohy
Amgad
A
Sandbhor
Mahendra
M
Cairo
Christopher W
CW
D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D001665:Binding Sites; D002384:Catalysis; D003198:Computer Simulation; D003300:Copper / Q000737:chemistry; D006801:Humans; D019158:N-Acetylneuraminic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D009439:Neuraminidase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013329:Structure-Activity Relationship; D014230:Triazoles / Q000737:chemistry*
C556352:2,3-didehydro-N-acetyl-neuraminic acid; D000480:Alkynes; D001386:Azides; D014230:Triazoles; D003300:Copper; C465436:Neu3 protein, human; D009439:Neuraminidase; D019158:N-Acetylneuraminic Acid