Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.
Höfling
S B
SB
Department für Chemie und Pharmazie, Pharmazeutische Chemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Maschauer
S
S
Hübner
H
H
Gmeiner
P
P
Wester
H-J
HJ
Prante
O
O
Heinrich
M R
MR
D000818:Animals; D001921:Brain / Q000378:metabolism; D004298:Dopamine; D005462:Fluorine Radioisotopes; D007553:Isotope Labeling; D008024:Ligands; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D051381:Rats; D050637:Receptors, Dopamine D3 / Q000737:chemistry*
D005462:Fluorine Radioisotopes; D008024:Ligands; D019275:Radiopharmaceuticals; D050637:Receptors, Dopamine D3; D004298:Dopamine