title: Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis.
authors.affiliation: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Erik
authors.initials: E
authors.lastname: Norberg
authors.forename: Marie
authors.initials: M
authors.lastname: Karlsson
authors.forename: Olga
authors.initials: O
authors.lastname: Korenovska
authors.forename: Susanne
authors.initials: S
authors.lastname: Szydlowski
authors.forename: Gilad
authors.initials: G
authors.lastname: Silberberg
authors.forename: Per
authors.initials: P
authors.lastname: Uhlén
authors.forename: Sten
authors.initials: S
authors.lastname: Orrenius
authors.forename: Boris
authors.initials: B
authors.lastname: Zhivotovsky
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D051033:Apoptosis Inducing Factor / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D002154:Calpain / Q000378:metabolism; D020169:Caspases / Q000378:metabolism; D002460:Cell Line; D045744:Cell Line, Tumor; D002478:Cells, Cultured; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D015870:Gene Expression; D057809:HEK293 Cells; D006801:Humans; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; D007473:Ion Channels / Q000235:genetics / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D010766:Phosphorylation; D015221:Potassium Channels; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D051381:Rats; D017207:Rats, Sprague-Dawley; D019311:Staurosporine / Q000031:analogs & derivatives / Q000494:pharmacology
chemical_list: D051033:Apoptosis Inducing Factor; D004791:Enzyme Inhibitors; C578710:HCN2 protein, human; C578712:Hcn2 protein, rat; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; D007473:Ion Channels; D015221:Potassium Channels; D011493:Protein Kinase C; D002154:Calpain; D020169:Caspases; D019311:Staurosporine; C059539:midostaurin; D002118:Calcium