title: The durable clearance of the T315I BCR-ABL mutated clone in chronic phase chronic myelogenous leukemia patients on omacetaxine allows tyrosine kinase inhibitor rechallenge.
authors.affiliation: Hematology Department, E. Herriot Hospital, Lyon, France.
authors.forename: Franck E
authors.initials: FE
authors.lastname: Nicolini
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Chomel
authors.forename: Lydia
authors.initials: L
authors.lastname: Roy
authors.forename: Laurence
authors.initials: L
authors.lastname: Legros
authors.forename: Kaddour
authors.initials: K
authors.lastname: Chabane
authors.forename: Sophie
authors.initials: S
authors.lastname: Ducastelle
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Nicolas-Virelizier
authors.forename: Mauricette
authors.initials: M
authors.lastname: Michallet
authors.forename: Isabelle
authors.initials: I
authors.lastname: Tigaud
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Magaud
authors.forename: Ali
authors.initials: A
authors.lastname: Turhan
authors.forename: François
authors.initials: F
authors.lastname: Guilhot
authors.forename: Sandrine
authors.initials: S
authors.lastname: Hayette
mesh_terms: D000328:Adult; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D019008:Drug Resistance, Neoplasm; D005260:Female; D016044:Fusion Proteins, bcr-abl / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D006248:Harringtonines / Q000627:therapeutic use*; D000077863:Homoharringtonine; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000235:genetics; D011743:Pyrimidines / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D006248:Harringtonines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D000077863:Homoharringtonine; D011505:Protein-Tyrosine Kinases; D016044:Fusion Proteins, bcr-abl; C498826:nilotinib