title: Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing.
authors.affiliation: First Department of Pathology, Wakayama Medical University School of Medicine, 811-1 Kimiidera, Wakayama 641-0012, Japan.
authors.forename: Motohisa
authors.initials: M
authors.lastname: Kawakatsu
authors.forename: Seiji
authors.initials: S
authors.lastname: Kanno
authors.forename: Ting
authors.initials: T
authors.lastname: Gui
authors.forename: Zhibo
authors.initials: Z
authors.lastname: Gai
authors.forename: Shunji
authors.initials: S
authors.lastname: Itoh
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanishima
authors.forename: Kosuke
authors.initials: K
authors.lastname: Oikawa
authors.forename: Yasuteru
authors.initials: Y
authors.lastname: Muragaki
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002146:Bony Callus / Q000166:cytology* / Q000378:metabolism / Q000473:pathology; D002454:Cell Differentiation; D020219:Chondrogenesis / Q000235:genetics; D005260:Female; D017102:Fracture Healing / Q000235:genetics*; D007527:Isoenzymes / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D010010:Osteoclasts / Q000378:metabolism / Q000473:pathology; D010012:Osteogenesis / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011859:Radiography; D055758:SOX9 Transcription Factor / Q000235:genetics / Q000378:metabolism; D051900:Smad3 Protein / Q000235:genetics / Q000502:physiology*; D000071681:Tartrate-Resistant Acid Phosphatase; D013977:Tibia / Q000000981:diagnostic imaging / Q000378:metabolism; D013997:Time Factors; D016212:Transforming Growth Factor beta / Q000235:genetics / Q000378:metabolism
chemical_list: D007527:Isoenzymes; D012333:RNA, Messenger; D055758:SOX9 Transcription Factor; D051900:Smad3 Protein; D016212:Transforming Growth Factor beta; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; C000605511:Acp5 protein, mouse; D000071681:Tartrate-Resistant Acid Phosphatase