Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression.
Li
Yun
Y
Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA.
Sattler
Rita
R
Yang
Eun Ju
EJ
Nunes
Alice
A
Ayukawa
Yoko
Y
Akhtar
Sadia
S
Ji
Grace
G
Zhang
Ping-Wu
PW
Rothstein
Jeffrey D
JD
D000470:Alkaloids / Q000494:pharmacology*; D027322:Amino Acid Transport System X-AG / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D001253:Astrocytes / Q000378:metabolism*; D018929:Cell Culture Techniques; D055808:Drug Discovery; D027342:Excitatory Amino Acid Transporter 2 / Q000235:genetics / Q000378:metabolism; D015870:Gene Expression / Q000187:drug effects; D018698:Glutamic Acid / Q000378:metabolism; D006247:Harmine / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D032443:Peganum; D008517:Phytotherapy; D028321:Plant Preparations / Q000494:pharmacology*; D011401:Promoter Regions, Genetic / Q000502:physiology; D012333:RNA, Messenger / Q000378:metabolism; D013234:Stem Cells; D015854:Up-Regulation / Q000187:drug effects
D000470:Alkaloids; D027322:Amino Acid Transport System X-AG; D027342:Excitatory Amino Acid Transporter 2; D028321:Plant Preparations; D012333:RNA, Messenger; D018698:Glutamic Acid; D006247:Harmine