Regulation of benzo[a]pyrene-mediated DNA- and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lung cells.
Gelhaus
Stacy L
SL
Center for Cancer Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6610, USA.
Harvey
Ronald G
RG
Penning
Trevor M
TM
Blair
Ian A
IA
D001564:Benzo(a)pyrene / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D018736:DNA Adducts / Q000032:analysis*; D003849:Deoxyguanosine / Q000737:chemistry; D004851:Epoxide Hydrolases / Q000378:metabolism; D005978:Glutathione / Q000737:chemistry*; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D000072317:Polychlorinated Dibenzodioxins / Q000737:chemistry / Q000494:pharmacology*; D018336:Receptors, Aryl Hydrocarbon / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization
D018736:DNA Adducts; D000072317:Polychlorinated Dibenzodioxins; D018336:Receptors, Aryl Hydrocarbon; D001564:Benzo(a)pyrene; D003577:Cytochrome P-450 Enzyme System; D004851:Epoxide Hydrolases; D003849:Deoxyguanosine; D005978:Glutathione