KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.
Pang
N K B
NK
Divisions of Cytopathology, Department of Pathology, National University Health System, Singapore.
Nga
M E
ME
Chin
S Y
SY
Ismail
T M
TM
Lim
G L
GL
Soong
R
R
Salto-Tellez
M
M
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology / Q000556:secondary; D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D044963:Biopsy, Fine-Needle / Q000379:methods; D000068818:Cetuximab; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology / Q000556:secondary; D020732:Cytogenetic Analysis / Q000379:methods*; D004252:DNA Mutational Analysis / Q000379:methods*; D066246:ErbB Receptors / Q000235:genetics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins / Q000235:genetics*
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D066246:ErbB Receptors; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins; D000068818:Cetuximab