The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells.
Terakado
Masahiro
M
Dept. of Internal Medicine, Nihon Univ. School of Medicine, Tokyo, Japan.
Gon
Yasuhiro
Y
Sekiyama
Akiko
A
Takeshita
Ikuko
I
Kozu
Yutaka
Y
Matsumoto
Ken
K
Takahashi
Noriaki
N
Hashimoto
Shu
S
D000402:Airway Obstruction / Q000503:physiopathology*; D002463:Cell Membrane Permeability / Q000187:drug effects / Q000502:physiology; D004815:Epidermal Growth Factor / Q000494:pharmacology; D004847:Epithelial Cells / Q000187:drug effects / Q000502:physiology*; D066246:ErbB Receptors / Q000187:drug effects / Q000276:immunology / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000502:physiology*; D048670:MAP Kinase Kinase 4 / Q000378:metabolism*; D020935:MAP Kinase Signaling System / Q000502:physiology*; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D019108:Tight Junctions / Q000187:drug effects / Q000502:physiology; D020830:rac1 GTP-Binding Protein / Q000502:physiology*
D004815:Epidermal Growth Factor; D066246:ErbB Receptors; D020928:Mitogen-Activated Protein Kinases; D048670:MAP Kinase Kinase 4; D020830:rac1 GTP-Binding Protein