title: An inhibitor-like binding mode of a carbonic anhydrase activator within the active site of isoform II.
authors.affiliation: Temple University School of Pharmacy, Department of Pharmaceutical Sciences, 3307 North Broad Street, Philadelphia, PA 19140, USA.
authors.forename: Khyati
authors.initials: K
authors.lastname: Dave
authors.forename: Marc A
authors.initials: MA
authors.lastname: Ilies
authors.forename: Andrea
authors.initials: A
authors.lastname: Scozzafava
authors.forename: Claudia
authors.initials: C
authors.lastname: Temperini
authors.forename: Daniela
authors.initials: D
authors.lastname: Vullo
authors.forename: Claudiu T
authors.initials: CT
authors.lastname: Supuran
mesh_terms: D024402:Carbonic Anhydrase II / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D002256:Carbonic Anhydrases; D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D020536:Enzyme Activators / Q000737:chemistry*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D011726:Pyridinium Compounds / Q000737:chemistry*
chemical_list: D020536:Enzyme Activators; D007093:Imidazoles; D011726:Pyridinium Compounds; C029899:imidazole; D024402:Carbonic Anhydrase II; D002256:Carbonic Anhydrases