GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity.
Walls
Anne B
AB
Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Norway.
Nilsen
Linn Hege
LH
Eyjolfsson
Elvar M
EM
Vestergaard
Henrik T
HT
Hansen
Suzanne L
SL
Schousboe
Arne
A
Sonnewald
Ursula
U
Waagepetersen
Helle S
HS
D000818:Animals; D002540:Cerebral Cortex / Q000201:enzymology / Q000378:metabolism; D003337:Corpus Callosum / Q000201:enzymology / Q000378:metabolism; D004827:Epilepsy / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D005968:Glutamate Decarboxylase / Q000172:deficiency / Q000502:physiology*; D007527:Isoenzymes / Q000172:deficiency / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009433:Neural Inhibition / Q000502:physiology*; D013572:Synaptic Vesicles / Q000201:enzymology / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000096:biosynthesis* / Q000502:physiology
D007527:Isoenzymes; D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase; C401141:glutamate decarboxylase 2