title: 5-amino-pyrazoles as potent and selective p38α inhibitors.
authors.affiliation: Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, USA. jagabandhu.das@bms.com
authors.forename: Jagabandhu
authors.initials: J
authors.lastname: Das
authors.forename: Robert V
authors.initials: RV
authors.lastname: Moquin
authors.forename: Alaric J
authors.initials: AJ
authors.lastname: Dyckman
authors.forename: Tianle
authors.initials: T
authors.lastname: Li
authors.forename: Sidney
authors.initials: S
authors.lastname: Pitt
authors.forename: Rosemary
authors.initials: R
authors.lastname: Zhang
authors.forename: Ding Ren
authors.initials: DR
authors.lastname: Shen
authors.forename: Kim W
authors.initials: KW
authors.lastname: McIntyre
authors.forename: Kathleen
authors.initials: K
authors.lastname: Gillooly
authors.forename: Arthur M
authors.initials: AM
authors.lastname: Doweyko
authors.forename: John A
authors.initials: JA
authors.lastname: Newitt
authors.forename: John S
authors.initials: JS
authors.lastname: Sack
authors.forename: Hongjian
authors.initials: H
authors.lastname: Zhang
authors.forename: Susan E
authors.initials: SE
authors.lastname: Kiefer
authors.forename: Kevin
authors.initials: K
authors.lastname: Kish
authors.forename: Murray
authors.initials: M
authors.lastname: McKinnon
authors.forename: Joel C
authors.initials: JC
authors.lastname: Barrish
authors.forename: John H
authors.initials: JH
authors.lastname: Dodd
authors.forename: Gary L
authors.initials: GL
authors.lastname: Schieven
authors.forename: Katerina
authors.initials: K
authors.lastname: Leftheris
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D051379:Mice; D048308:Mitogen-Activated Protein Kinase 14 / Q000037:antagonists & inhibitors / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation; D047428:Protein Kinase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000096:biosynthesis
chemical_list: D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D014409:Tumor Necrosis Factor-alpha; D048308:Mitogen-Activated Protein Kinase 14