Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia.
Sathyasaikumar
Korrapati V
KV
Maryland Psychiatric Research Center, Baltimore, MD, USA.
Stachowski
Erin K
EK
Wonodi
Ikwunga
I
Roberts
Rosalinda C
RC
Rassoulpour
Arash
A
McMahon
Robert P
RP
Schwarcz
Robert
R
D000328:Adult; D000368:Aged; D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007737:Kynurenine / Q000378:metabolism*; D050601:Kynurenine 3-Monooxygenase / Q000378:metabolism; D008297:Male; D053858:Metabolic Networks and Pathways / Q000187:drug effects; D008875:Middle Aged; D010088:Oxidoreductases / Q000378:metabolism; D010430:Pentosyltransferases / Q000378:metabolism; D011180:Postmortem Changes; D017397:Prefrontal Cortex / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D018967:Risperidone / Q000494:pharmacology; D012559:Schizophrenia / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism; D000098553:Nicotinate-Nucleotide Diphosphorylase (Carboxylating)
D014150:Antipsychotic Agents; D007737:Kynurenine; D010088:Oxidoreductases; C026382:3-hydroxyanthranilic acid oxidase; D050601:Kynurenine 3-Monooxygenase; D010430:Pentosyltransferases; D000098553:Nicotinate-Nucleotide Diphosphorylase (Carboxylating); D000637:Transaminases; C021481:kynurenine-oxoglutarate transaminase; D018967:Risperidone