Plexin B1 inhibits integrin-dependent pp125FAK and Rho activity in melanoma.
McClelland
Lindy
L
Department of Dermatology, University of Rochester School of Medicine, Rochester, NY, USA.
Chen
Yulin
Y
Soong
Joanne
J
Kuo
Ihsin
I
Scott
Glynis
G
D000818:Animals; D001485:Basement Membrane / Q000187:drug effects / Q000378:metabolism; D002417:Cattle; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D005353:Fibronectins / Q000494:pharmacology; D051417:Focal Adhesion Kinase 1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D008545:Melanoma / Q000201:enzymology* / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*; D020741:rho GTP-Binding Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism
D005353:Fibronectins; D016023:Integrins; D009419:Nerve Tissue Proteins; C492119:PLXNB1 protein, human; D011956:Receptors, Cell Surface; D051417:Focal Adhesion Kinase 1; C496050:PTK2 protein, human; D020741:rho GTP-Binding Proteins