A facile and stereocontrolled synthesis of γ-substituted γ-fluoroglutamates by conjugate addition: conflicting effect between fluorinated enaminoester and hinderered Michael acceptor.
Drège
Emmanuelle
E
Univ. Paris-Sud, Equipe de Synthèse Organique et de Pharmacochimie, UMR CNRS 8076, 5, rue Jean-Baptiste Clément, Châtenay-Malabry, F-92296, France.
Guillaume
Anaïs
A
Boukhedimi
Nadjia
N
Marrot
Jérôme
J
Troufflard
Claire
C
Tran Huu-Dau
Marie-Elise
ME
Joseph
Delphine
D
Delarue-Cochin
Sandrine
S
D000409:Alanine / Q000031:analogs & derivatives* / Q000737:chemistry; D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D005971:Glutamates / Q000138:chemical synthesis* / Q000737:chemistry; D054879:Halogenation; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
D005971:Glutamates; C457541:N-acetyldehydroalanine; D005461:Fluorine; D000409:Alanine