Multivalent DNA vaccine induces protective immune responses and enhanced resistance against Cryptosporidium parvum infection.
Wang
Chengmin
C
National Research Center for Wildlife Born Diseases, Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
Luo
Jing
J
Amer
Said
S
Guo
Yunhai
Y
Hu
Yi
Y
Lu
Yanmin
Y
Wang
Haijing
H
Duan
Mingxing
M
He
Hongxuan
H
D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D003457:Cryptosporidiosis / Q000276:immunology / Q000517:prevention & control*; D016785:Cryptosporidium parvum / Q000235:genetics / Q000276:immunology*; D005260:Female; D015870:Gene Expression; D005822:Genetic Vectors; D006023:Glycoproteins / Q000235:genetics / Q000276:immunology; D007371:Interferon-gamma / Q000378:metabolism; D053762:Interleukin-12 Subunit p40 / Q000172:deficiency / Q000276:immunology; D008565:Membrane Proteins / Q000235:genetics / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D010957:Plasmids; D015800:Protozoan Proteins / Q000235:genetics / Q000276:immunology; D016052:Protozoan Vaccines / Q000235:genetics / Q000276:immunology*; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology; D019444:Vaccines, DNA / Q000235:genetics / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000913:Antibodies, Protozoan; D006023:Glycoproteins; D053762:Interleukin-12 Subunit p40; D008565:Membrane Proteins; D015800:Protozoan Proteins; D016052:Protozoan Vaccines; D019444:Vaccines, DNA; D007371:Interferon-gamma