The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males.
Place
Ned J
NJ
Department of Population Medicine & Diagnostic Sciences, Cornell University, Ithaca, NY 14853, USA. njp27@cornell.edu
Coscia
Elizabeth M
EM
Dahl
Nancy J
NJ
Drea
Christine M
CM
Holekamp
Kay E
KE
Roser
Janet F
JF
Sisk
Cheryl L
CL
Weldele
Mary L
ML
Glickman
Stephen E
SE
D000726:Androgen Antagonists / Q000494:pharmacology*; D000735:Androstenedione / Q000097:blood*; D000818:Animals; D004958:Estradiol / Q000097:blood; D005246:Feedback; D005260:Female; D018120:Finasteride / Q000494:pharmacology*; D005485:Flutamide / Q000494:pharmacology*; D045968:Hyaenidae / Q000502:physiology*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D012733:Sex Differentiation / Q000187:drug effects; D012737:Sex Factors; D013739:Testosterone / Q000097:blood
D000726:Androgen Antagonists; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol; D018120:Finasteride; D005485:Flutamide; D007986:Luteinizing Hormone