Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity.
Sausen de Freitas
Andressa
A
Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, 97105-900, Santa Maria RS, Brazil. andressasausen@yahoo.com.br
de Souza Prestes
Alessandro
A
Wagner
Caroline
C
Haigert Sudati
Jéssie
J
Alves
Diego
D
Oliveira Porciúncula
Lisiane
L
Kade
Ige Joseph
IJ
Teixeira Rocha
João Batista
JB
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001555:Benzene Derivatives / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000378:metabolism*; D008322:Mammals / Q000378:metabolism*; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000378:metabolism*; D010084:Oxidation-Reduction; D013880:Thioredoxin-Disulfide Reductase / Q000378:metabolism*
D000975:Antioxidants; D001555:Benzene Derivatives; D016566:Organoselenium Compounds; C061132:diphenyldiselenide; D005979:Glutathione Peroxidase; D013880:Thioredoxin-Disulfide Reductase