p67/MetAP2 suppresses K-RasV12-mediated transformation of NIH3T3 mouse fibroblasts in culture and in athymic mice.
Majumdar
Avijit
A
School of Biomedical Sciences, Kent State University, Kent, Ohio 44242, United States.
Ghosh
Arnab
A
Datta
Samit
S
Prudner
Bethany C
BC
Datta
Bansidhar
B
D000626:Aminopeptidases / Q000502:physiology*; D000818:Animals; D002460:Cell Line; D003510:Cyclohexanes / Q000494:pharmacology; D048049:Extracellular Signal-Regulated MAP Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology; D011905:Genes, ras / Q000235:genetics; D006023:Glycoproteins / Q000502:physiology*; D006801:Humans; D063208:Methionyl Aminopeptidases; D051379:Mice; D008819:Mice, Nude; D019950:Mitogen-Activated Protein Kinase 1 / Q000037:antagonists & inhibitors; D048052:Mitogen-Activated Protein Kinase 3 / Q000037:antagonists & inhibitors; D020929:Mitogen-Activated Protein Kinase Kinases / Q000378:metabolism; D010446:Peptide Fragments / Q000378:metabolism; D051381:Rats; D012717:Sesquiterpenes / Q000494:pharmacology; D015398:Signal Transduction / Q000187:drug effects; D014162:Transfection
D003510:Cyclohexanes; D005231:Fatty Acids, Unsaturated; D006023:Glycoproteins; D010446:Peptide Fragments; D012717:Sesquiterpenes; C026211:fumagillin; D048049:Extracellular Signal-Regulated MAP Kinases; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D020929:Mitogen-Activated Protein Kinase Kinases; D000626:Aminopeptidases; C081311:METAP2 protein, human; C489895:Metap2 protein, rat; D063208:Methionyl Aminopeptidases