β-D-Glucosyl-(1-4)-α-L-thevetosides of 17β-digitoxigenin from seeds of Cerbera manghas L. induces apoptosis in human hepatocellular carcinoma HepG2 cells.
Feng
Bo
B
Department of Biochemistry and Molecular Biology, Second Military Medical University, Shanghai 200433, People's Republic of China.
Guo
Yue-Wei
YW
Huang
Cai-Guo
CG
Li
Liang
L
Jiao
Bing-Hua
BH
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D029062:Apocynaceae / Q000737:chemistry*; D017209:Apoptosis / Q000187:drug effects*; D015153:Blotting, Western; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002301:Cardiac Glycosides / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D053938:DNA Fragmentation / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D005434:Flow Cytometry; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D053078:Membrane Potential, Mitochondrial; D051379:Mice; D008856:Microscopy, Fluorescence; D008517:Phytotherapy / Q000379:methods; D012639:Seeds / Q000737:chemistry
D000970:Antineoplastic Agents; D002301:Cardiac Glycosides; C574660:GHSC-73