The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.
Sullivan
Bradley P
BP
Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.
Weinreb
Paul H
PH
Violette
Shelia M
SM
Luyendyk
James P
JP
D000328:Adult; D000368:Aged; D000818:Animals; D001653:Bile Ducts, Intrahepatic / Q000378:metabolism / Q000473:pathology; D001779:Blood Coagulation Factors / Q000502:physiology*; D002478:Cells, Cultured; D002779:Cholestasis / Q000150:complications* / Q000235:genetics / Q000378:metabolism; D005260:Female; D015870:Gene Expression; D006801:Humans; D039564:Integrin alphaV / Q000235:genetics* / Q000378:metabolism; D039641:Integrin beta Chains / Q000235:genetics* / Q000378:metabolism; D008103:Liver Cirrhosis / Q000209:etiology* / Q000235:genetics / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D008875:Middle Aged; D051381:Rats; D044463:Receptor, PAR-1 / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D013925:Thromboplastin / Q000235:genetics / Q000378:metabolism / Q000502:physiology
D001779:Blood Coagulation Factors; D039564:Integrin alphaV; D039641:Integrin beta Chains; D044463:Receptor, PAR-1; C072170:integrin beta6; D013925:Thromboplastin