Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress.
Mougiakakos
Dimitrios
D
Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden. Mougiakakos@ki.se
Johansson
C Christian
CC
Jitschin
Regina
R
Böttcher
Martin
M
Kiessling
Rolf
R
D000222:Adaptation, Physiological / Q000502:physiology*; D002478:Cells, Cultured; D004797:Enzyme-Linked Immunosorbent Assay; D005434:Flow Cytometry; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D016877:Oxidants / Q000494:pharmacology; D018384:Oxidative Stress; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013438:Sulfhydryl Compounds / Q000378:metabolism; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000378:metabolism*; D013879:Thioredoxins / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D016877:Oxidants; D013438:Sulfhydryl Compounds; D014409:Tumor Necrosis Factor-alpha; D013879:Thioredoxins; D006861:Hydrogen Peroxide