Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells.
Gehrmann
W
W
Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.
Elsner
M
M
Lenzen
S
S
D017209:Apoptosis / Q000187:drug effects; D005230:Fatty Acids, Nonesterified / Q000494:pharmacology; D005786:Gene Expression Regulation; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology; D050417:Insulin-Secreting Cells / Q000166:cytology / Q000378:metabolism*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects; D017382:Reactive Oxygen Species / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000502:physiology
C473034:FFAR1 protein, human; C519853:FFAR4 protein, human; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D017382:Reactive Oxygen Species; D043562:Receptors, G-Protein-Coupled; D006861:Hydrogen Peroxide