Normal red blood cells partially decrease diepoxybutane-induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients.
Porto
B
B
Laboratory of Cytogenetics, ICBAS-Institute of Biomedical Sciences Abel Salazar, UP, Porto, Portugal. bporto@icbas.up.pt
Sousa
R
R
Malheiro
I
I
Gaspar
J
J
Rueff
J
J
Gonçalves
C
C
Barbot
J
J
D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D019457:Chromosome Breakage / Q000187:drug effects*; D020732:Cytogenetic Analysis; D004852:Epoxy Compounds / Q000633:toxicity*; D004912:Erythrocytes / Q000187:drug effects* / Q000502:physiology*; D005199:Fanconi Anemia / Q000473:pathology*; D005260:Female; D017353:Gene Deletion; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male
D004852:Epoxy Compounds; C007366:diepoxybutane; C413545:glutathione S-transferase T1; D005982:Glutathione Transferase