title: SARS coronavirus 8b reduces viral replication by down-regulating E via an ubiquitin-independent proteasome pathway.
authors.affiliation: Collaborative Anti-Viral Research Group, Institute of Molecular and Cell Biology, Singapore.
authors.forename: Choong-Tat
authors.initials: CT
authors.lastname: Keng
authors.forename: Sara
authors.initials: S
authors.lastname: Akerström
authors.forename: Cynthia Sau-Wai
authors.initials: CS
authors.lastname: Leung
authors.forename: Leo L M
authors.initials: LL
authors.lastname: Poon
authors.forename: J S Malik
authors.initials: JS
authors.lastname: Peiris
authors.forename: Ali
authors.initials: A
authors.lastname: Mirazimi
authors.forename: Yee-Joo
authors.initials: YJ
authors.lastname: Tan
mesh_terms: D000818:Animals; D002522:Chlorocebus aethiops; D018352:Coronavirus Infections / Q000378:metabolism; D015536:Down-Regulation; D015967:Gene Expression Regulation, Viral; D055786:Gene Knockout Techniques; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D016297:Mutagenesis, Site-Directed; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism*; D055550:Protein Stability; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D025801:Ubiquitin / Q000378:metabolism; D054875:Ubiquitination / Q000235:genetics; D014709:Vero Cells; D014759:Viral Envelope Proteins / Q000378:metabolism*; D014764:Viral Proteins / Q000378:metabolism*; D000086082:Viroporin Proteins; D014779:Virus Replication / Q000235:genetics*
chemical_list: C501689:E protein, SARS coronavirus; D025801:Ubiquitin; D014759:Viral Envelope Proteins; D014764:Viral Proteins; D000086082:Viroporin Proteins; D049452:Green Fluorescent Proteins; D046988:Proteasome Endopeptidase Complex