Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.
Oyer
Jon A
JA
Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, USA.
Yates
Phillip A
PA
Godsey
Sarah
S
Turker
Mitchell S
MS
D000228:Adenine Phosphoribosyltransferase / Q000235:genetics*; D000818:Animals; D001374:Azacitidine / Q000031:analogs & derivatives / Q000494:pharmacology; D045744:Cell Line, Tumor; D047369:Chromatin Immunoprecipitation; D018899:CpG Islands / Q000235:genetics*; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000037:antagonists & inhibitors; D000077209:Decitabine; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology; D006657:Histones / Q000378:metabolism; D006877:Hydroxamic Acids / Q000494:pharmacology; D008239:Lysine / Q000378:metabolism; D008745:Methylation; D051379:Mice; D011401:Promoter Regions, Genetic / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013997:Time Factors
D056572:Histone Deacetylase Inhibitors; D006657:Histones; D006877:Hydroxamic Acids; C012589:trichostatin A; D000077209:Decitabine; D015254:DNA Modification Methylases; D000228:Adenine Phosphoribosyltransferase; D008239:Lysine; D001374:Azacitidine