title: Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.
authors.affiliation: Department of Surgery, University of British Columbia, and Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
authors.forename: Alicia N
authors.initials: AN
authors.lastname: McMurchy
authors.forename: Jana
authors.initials: J
authors.lastname: Gillies
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Allan
authors.forename: Laura
authors.initials: L
authors.lastname: Passerini
authors.forename: Eleonora
authors.initials: E
authors.lastname: Gambineri
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Roncarolo
authors.forename: Rosa
authors.initials: R
authors.lastname: Bacchetta
authors.forename: Megan K
authors.initials: MK
authors.lastname: Levings
mesh_terms: D000293:Adolescent; D015704:CD4 Antigens / Q000096:biosynthesis; D049109:Cell Proliferation; D054338:Cell Transdifferentiation / Q000235:genetics; D002478:Cells, Cultured; D002648:Child; D016207:Cytokines / Q000235:genetics / Q000378:metabolism; D051858:Forkhead Transcription Factors / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000235:genetics* / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D007165:Immunosuppression Therapy; D050505:Mutant Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D017354:Point Mutation / Q000235:genetics; D016884:Polyendocrinopathies, Autoimmune; D016176:T-Lymphocyte Subsets / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D019076:Transgenes / Q000235:genetics; D055815:Young Adult
chemical_list: D015704:CD4 Antigens; D016207:Cytokines; C418974:FOXP3 protein, human; D051858:Forkhead Transcription Factors; D050505:Mutant Proteins