title: α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1.
authors.affiliation: Institute of Physiology, National Yang-Ming University, Taipei 11211, Taiwan.
authors.forename: Li-Ching
authors.initials: LC
authors.lastname: Cheng
authors.forename: Kuo-Hui
authors.initials: KH
authors.lastname: Su
authors.forename: Yu Ru
authors.initials: YR
authors.lastname: Kou
authors.forename: Song-Kun
authors.initials: SK
authors.lastname: Shyue
authors.forename: Li-Chieh
authors.initials: LC
authors.lastname: Ching
authors.forename: Yuan-Bin
authors.initials: YB
authors.lastname: Yu
authors.forename: Yuh-Lin
authors.initials: YL
authors.lastname: Wu
authors.forename: Ching-Chian
authors.initials: CC
authors.lastname: Pan
authors.forename: Tzong-Shyuan
authors.initials: TS
authors.lastname: Lee
mesh_terms: D064286:ATP Binding Cassette Transporter 1; D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D002478:Cells, Cultured; D005487:Foam Cells / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008074:Lipoproteins / Q000235:genetics* / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D000071518:Liver X Receptors; D051379:Mice; D057093:Orphan Nuclear Receptors / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000502:physiology*; D011106:Polyisoprenyl Phosphates / Q000494:pharmacology; D034741:RNA, Small Interfering / Q000494:pharmacology; D020218:Response Elements / Q000187:drug effects; D008063:Thioctic Acid / Q000494:pharmacology*; D015533:Transcriptional Activation / Q000187:drug effects / Q000502:physiology; D014162:Transfection; D015854:Up-Regulation / Q000187:drug effects
chemical_list: C577836:ABCA1 protein, human; C487540:ABCG1 protein, mouse; D064286:ATP Binding Cassette Transporter 1; D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters; D008074:Lipoproteins; D008077:Lipoproteins, LDL; D000071518:Liver X Receptors; C000605213:NR1H3 protein, human; C000605214:Nr1h3 protein, mouse; D057093:Orphan Nuclear Receptors; D011106:Polyisoprenyl Phosphates; D034741:RNA, Small Interfering; C099252:oxidized low density lipoprotein; D008063:Thioctic Acid; C002963:geranylgeranyl pyrophosphate