The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target.
Stieger
Bruno
B
Division of Clinical Pharmacology and Toxicology, University Hospital, Zurich, Switzerland. bstieger@kpt.unizh.ch
Beuers
Ulrich
U
D000074020:ATP Binding Cassette Transporter, Subfamily B, Member 11; D018528:ATP-Binding Cassette Transporters / Q000378:metabolism*; D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D001648:Bile Canaliculi / Q000378:metabolism*; D002779:Cholestasis / Q000378:metabolism; D004764:Enterohepatic Circulation; D006801:Humans; D008099:Liver / Q000502:physiology / Q000503:physiopathology*; D008107:Liver Diseases / Q000188:drug therapy* / Q000209:etiology / Q000235:genetics / Q000378:metabolism*; D058990:Molecular Targeted Therapy
C093491:ABCB11 protein, human; D000074020:ATP Binding Cassette Transporter, Subfamily B, Member 11; D018528:ATP-Binding Cassette Transporters; D001647:Bile Acids and Salts