Towards therapeutic antibodies to membrane oncoproteins by a robust strategy using rats immunized with transfectants expressing target molecules fused to green fluorescent protein.
Masuko
Takashi
T
Cell Biology Laboratory, Department of Pharmaceutical Sciences, School of Pharmacy, Kinki University, Osaka, Japan. masuko@phar.kindai.ac.jp
Ohno
Yoshiya
Y
Masuko
Kazue
K
Yagi
Hideki
H
Uejima
Shinya
S
Takechi
Masayuki
M
Hashimoto
Yoshiyuki
Y
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis / Q000627:therapeutic use*; D000912:Antibodies, Neoplasm / Q000627:therapeutic use*; D002460:Cell Line; D049452:Green Fluorescent Proteins / Q000235:genetics*; D006801:Humans; D018960:Hyaluronan Receptors / Q000276:immunology; D007114:Immunization; D008565:Membrane Proteins / Q000276:immunology*; D015513:Oncogene Proteins / Q000235:genetics / Q000276:immunology*; D019151:Peptide Library; D051381:Rats; D011990:Receptors, Transferrin / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D014162:Transfection
D000911:Antibodies, Monoclonal; D000912:Antibodies, Neoplasm; D018960:Hyaluronan Receptors; D008565:Membrane Proteins; D015513:Oncogene Proteins; D019151:Peptide Library; D011990:Receptors, Transferrin; D011993:Recombinant Fusion Proteins; D049452:Green Fluorescent Proteins