Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1α in retinal vascular endothelial cells.
You
Jian-Jang
JJ
Keelung General Hospital, Department of Health, The Executive Yuan, Keelung, Taiwan.
Yang
Chung-May
CM
Chen
Muh-Shy
MS
Yang
Chang-Hao
CH
D000818:Animals; D015153:Blotting, Western; D002478:Cells, Cultured; D055515:Cysteine-Rich Protein 61 / Q000235:genetics* / Q000378:metabolism; D024202:Electrophoretic Mobility Shift Assay; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005786:Gene Expression Regulation / Q000502:physiology*; D017930:Genes, Reporter; D000860:Hypoxia / Q000378:metabolism*; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000378:metabolism*; D008251:Macaca; D016297:Mutagenesis, Site-Directed; D018919:Neovascularization, Physiologic; D010766:Phosphorylation; D016755:Proto-Oncogene Proteins c-jun / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics; D012171:Retinal Vessels / Q000166:cytology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018808:Transcription Factor AP-1 / Q000378:metabolism*
D055515:Cysteine-Rich Protein 61; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D016755:Proto-Oncogene Proteins c-jun; D012333:RNA, Messenger; D018808:Transcription Factor AP-1