title: A biochemical mechanism for the oncogenic potential of the p110beta catalytic subunit of phosphoinositide 3-kinase.
authors.affiliation: Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
authors.forename: Hashem A
authors.initials: HA
authors.lastname: Dbouk
authors.forename: Huan
authors.initials: H
authors.lastname: Pang
authors.forename: Andras
authors.initials: A
authors.lastname: Fiser
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Backer
mesh_terms: D000595:Amino Acid Sequence; D019943:Amino Acid Substitution / Q000235:genetics; D000818:Animals; D020134:Catalytic Domain; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D058534:Class I Phosphatidylinositol 3-Kinases; D057809:HEK293 Cells; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D050505:Mutant Proteins / Q000737:chemistry / Q000378:metabolism; D041681:NIH 3T3 Cells; D019869:Phosphatidylinositol 3-Kinases / Q000737:chemistry / Q000378:metabolism*; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction; D013329:Structure-Activity Relationship; D018909:src Homology Domains
chemical_list: D050505:Mutant Proteins; D011994:Recombinant Proteins; D019869:Phosphatidylinositol 3-Kinases; D058534:Class I Phosphatidylinositol 3-Kinases; C497132:PIK3CB protein, human