title: Recombinant chimeric lectins consisting of mannose-binding lectin and L-ficolin are potent inhibitors of influenza A virus compared with mannose-binding lectin.
authors.affiliation: Program of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: Wei-Chuan
authors.initials: WC
authors.lastname: Chang
authors.forename: Kevan L
authors.initials: KL
authors.lastname: Hartshorn
authors.forename: Mitchell R
authors.initials: MR
authors.lastname: White
authors.forename: Patience
authors.initials: P
authors.lastname: Moyo
authors.forename: Ian C
authors.initials: IC
authors.lastname: Michelow
authors.forename: Henry
authors.initials: H
authors.lastname: Koziel
authors.forename: Bernard T
authors.initials: BT
authors.lastname: Kinane
authors.forename: Emmett V
authors.initials: EV
authors.lastname: Schmidt
authors.forename: Teizo
authors.initials: T
authors.lastname: Fujita
authors.forename: Kazue
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D003167:Complement Activation; D037582:Complement Pathway, Mannose-Binding Lectin / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006387:Hemagglutination, Viral / Q000187:drug effects; D009980:Influenza A virus / Q000737:chemistry / Q000187:drug effects*; D037102:Lectins / Q000737:chemistry / Q000494:pharmacology*; D037601:Mannose-Binding Lectin / Q000737:chemistry / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009439:Neuraminidase / Q000037:antagonists & inhibitors; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000494:pharmacology*; D000097604:Ficolins
chemical_list: D000998:Antiviral Agents; D037102:Lectins; D037601:Mannose-Binding Lectin; D009439:Neuraminidase; D011993:Recombinant Fusion Proteins; D000097604:Ficolins