Nedd4L modulates the transcription of metalloproteinase-1 and -13 genes to increase the invasive activity of gallbladder cancer.
Takeuchi
Tamotsu
T
Department of Pathology, Kochi Medical School, Nankoku, Japan. takeutit08@gmail.com
Adachi
Yoshihiro
Y
Nagayama
Tomoko
T
Furihata
Mutsuo
M
D000230:Adenocarcinoma / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D000368:Aged; D045744:Cell Line, Tumor; D015536:Down-Regulation; D056827:Endosomal Sorting Complexes Required for Transport / Q000235:genetics* / Q000378:metabolism; D005260:Female; D005706:Gallbladder Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic; D020868:Gene Silencing; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D020781:Matrix Metalloproteinase 1 / Q000235:genetics* / Q000378:metabolism; D053509:Matrix Metalloproteinase 13 / Q000235:genetics* / Q000378:metabolism; D008875:Middle Aged; D000075702:Nedd4 Ubiquitin Protein Ligases; D009361:Neoplasm Invasiveness; D034741:RNA, Small Interfering / Q000235:genetics; D014158:Transcription, Genetic; D015533:Transcriptional Activation; D044767:Ubiquitin-Protein Ligases / Q000235:genetics* / Q000378:metabolism
D056827:Endosomal Sorting Complexes Required for Transport; D034741:RNA, Small Interfering; D000075702:Nedd4 Ubiquitin Protein Ligases; C000618483:Nedd4 protein, human; C000618485:Nedd4L protein, human; D044767:Ubiquitin-Protein Ligases; D053509:Matrix Metalloproteinase 13; D020781:Matrix Metalloproteinase 1