title: Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C.
authors.affiliation: Service d'hépatologie and INSERM CRB3, Hôpital Beaujon, APHP, Université Denis Diderot Paris 7, Clichy, France. patrick.marcellin@bjn.aphp.fr
authors.forename: Patrick
authors.initials: P
authors.lastname: Marcellin
authors.forename: Xavier
authors.initials: X
authors.lastname: Forns
authors.forename: Tobias
authors.initials: T
authors.lastname: Goeser
authors.forename: Peter
authors.initials: P
authors.lastname: Ferenci
authors.forename: Frederik
authors.initials: F
authors.lastname: Nevens
authors.forename: Giampiero
authors.initials: G
authors.lastname: Carosi
authors.forename: Joost P
authors.initials: JP
authors.lastname: Drenth
authors.forename: Lawrence
authors.initials: L
authors.lastname: Serfaty
authors.forename: Koen
authors.initials: K
authors.lastname: De Backer
authors.forename: Rolf
authors.initials: R
authors.lastname: Van Heeswijk
authors.forename: Donghan
authors.initials: D
authors.lastname: Luo
authors.forename: Gaston
authors.initials: G
authors.lastname: Picchio
authors.forename: Maria
authors.initials: M
authors.lastname: Beumont
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D016174:Hepacivirus / Q000187:drug effects; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009842:Oligopeptides / Q000493:pharmacokinetics / Q000627:therapeutic use*; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D012367:RNA, Viral / Q000032:analysis / Q000187:drug effects; D011994:Recombinant Proteins; D012254:Ribavirin / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D009842:Oligopeptides; D012367:RNA, Viral; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C486464:telaprevir; C417083:peginterferon alfa-2b; C100416:peginterferon alfa-2a