Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure.
Boutaud
Olivier
O
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA. olivier.boutaud@vanderbilt.edu
Roberts
L Jackson
LJ
D000082:Acetaminophen / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000378:metabolism; D007501:Iron / Q000737:chemistry / Q000378:metabolism; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D058990:Molecular Targeted Therapy / Q000639:trends; D009211:Myoglobin / Q000378:metabolism*; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects; D051437:Renal Insufficiency / Q000517:prevention & control; D012206:Rhabdomyolysis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D014661:Vasoconstriction / Q000187:drug effects
D009211:Myoglobin; D000082:Acetaminophen; D006861:Hydrogen Peroxide; D007501:Iron