Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas.
Fields
Emma C
EC
Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Damek
Denise
D
Gaspar
Laurie E
LE
Liu
Arthur K
AK
Kavanagh
Brian D
BD
Waziri
Allen
A
Lillehei
Kevin
K
Chen
Changhu
C
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D016190:Carboplatin / Q000008:administration & dosage; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000379:methods; D003606:Dacarbazine / Q000008:administration & dosage / Q000031:analogs & derivatives; D003907:Dexamethasone / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D005910:Glioma / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D000077146:Irinotecan; D008297:Male; D020714:Maximum Tolerated Dose; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010880:Piperidines / Q000008:administration & dosage* / Q000009:adverse effects; D011446:Prospective Studies; D011799:Quinazolines / Q000008:administration & dosage* / Q000009:adverse effects; D016634:Radiosurgery / Q000379:methods*; D011879:Radiotherapy Dosage; D000077204:Temozolomide; D047368:Tumor Burden; D014750:Vincristine / Q000008:administration & dosage; D055815:Young Adult
D000970:Antineoplastic Agents; D005938:Glucocorticoids; D010880:Piperidines; D011799:Quinazolines; D014750:Vincristine; D000077146:Irinotecan; D003606:Dacarbazine; D003907:Dexamethasone; D016190:Carboplatin; D002166:Camptothecin; D000077204:Temozolomide; C452423:vandetanib