Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.
Chen
Shi
S
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Burgin
Sarah
S
McDaniel
Andrew
A
Li
Xiaohong
X
Yuan
Jin
J
Chen
Mia
M
Khalaf
Waleed
W
Clapp
D Wade
DW
Yang
Feng-Chun
FC
D000818:Animals; D015550:Cell Degranulation / Q000187:drug effects* / Q000235:genetics; D002478:Cells, Cultured; D017077:Culture Media, Conditioned / Q000378:metabolism / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects / Q000235:genetics; D016514:Genes, Neurofibromatosis 1; D008407:Mast Cells / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D025542:Neurofibromin 1 / Q000378:metabolism / Q000502:physiology; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D012583:Schwann Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology
D017077:Culture Media, Conditioned; D025542:Neurofibromin 1; D019869:Phosphatidylinositol 3-Kinases; D019009:Proto-Oncogene Proteins c-kit