Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling.
Motorin
Yuri
Y
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany.
Burhenne
Jürgen
J
Teimer
Roman
R
Koynov
Kaloian
K
Willnow
Sophie
S
Weinhold
Elmar
E
Helm
Mark
M
D000480:Alkynes / Q000378:metabolism; D001483:Base Sequence; D057930:Click Chemistry; D005456:Fluorescent Dyes; D008969:Molecular Sequence Data; D009930:Organic Chemicals; D012360:RNA, Transfer, Phe / Q000737:chemistry* / Q000378:metabolism; D012436:S-Adenosylmethionine / Q000031:analogs & derivatives / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D012359:tRNA Methyltransferases / Q000378:metabolism*
C558458:AdoEnYn; C417664:Alexa594; D000480:Alkynes; D005456:Fluorescent Dyes; D009930:Organic Chemicals; D012360:RNA, Transfer, Phe; D012436:S-Adenosylmethionine; D012359:tRNA Methyltransferases