α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1.
Cheng
Li-Ching
LC
Institute of Physiology, National Yang-Ming University, Taipei 11211, Taiwan.
Su
Kuo-Hui
KH
Kou
Yu Ru
YR
Shyue
Song-Kun
SK
Ching
Li-Chieh
LC
Yu
Yuan-Bin
YB
Wu
Yuh-Lin
YL
Pan
Ching-Chian
CC
Lee
Tzong-Shyuan
TS
D064286:ATP Binding Cassette Transporter 1; D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D002478:Cells, Cultured; D005487:Foam Cells / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008074:Lipoproteins / Q000235:genetics* / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D000071518:Liver X Receptors; D051379:Mice; D057093:Orphan Nuclear Receptors / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000502:physiology*; D011106:Polyisoprenyl Phosphates / Q000494:pharmacology; D034741:RNA, Small Interfering / Q000494:pharmacology; D020218:Response Elements / Q000187:drug effects; D008063:Thioctic Acid / Q000494:pharmacology*; D015533:Transcriptional Activation / Q000187:drug effects / Q000502:physiology; D014162:Transfection; D015854:Up-Regulation / Q000187:drug effects
C577836:ABCA1 protein, human; C487540:ABCG1 protein, mouse; D064286:ATP Binding Cassette Transporter 1; D000070998:ATP Binding Cassette Transporter, Subfamily G, Member 1; D018528:ATP-Binding Cassette Transporters; D008074:Lipoproteins; D008077:Lipoproteins, LDL; D000071518:Liver X Receptors; C000605213:NR1H3 protein, human; C000605214:Nr1h3 protein, mouse; D057093:Orphan Nuclear Receptors; D011106:Polyisoprenyl Phosphates; D034741:RNA, Small Interfering; C099252:oxidized low density lipoprotein; D008063:Thioctic Acid; C002963:geranylgeranyl pyrophosphate