Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.
Garofalo
Antonio
A
Univ Lille Nord de France, F-59000 Lille, France.
Goossens
Laurence
L
Baldeyrou
Brigitte
B
Lemoine
Amélie
A
Ravez
Séverine
S
Six
Perrine
P
David-Cordonnier
Marie-Hélène
MH
Bonte
Jean-Paul
JP
Depreux
Patrick
P
Lansiaux
Amélie
A
Goossens
Jean-François
JF
D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D005453:Fluorescence; D006801:Humans; D007364:Intercalating Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D009690:Nucleic Acid Conformation; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D059004:Topoisomerase I Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D044366:Transition Temperature
D000814:Aniline Compounds; D000970:Antineoplastic Agents; D007364:Intercalating Agents; D011799:Quinazolines; D059004:Topoisomerase I Inhibitors; D004247:DNA