title: Evaluation and discrimination of simvastatin-induced structural alterations in proteins of different rat tissues by FTIR spectroscopy and neural network analysis.
authors.affiliation: Department of Biochemistry, Middle East Technical University, Ankara, 06531, Turkey.
authors.forename: Sebnem
authors.initials: S
authors.lastname: Garip
authors.forename: Engin
authors.initials: E
authors.lastname: Yapici
authors.forename: Nihal Simsek
authors.initials: NS
authors.lastname: Ozek
authors.forename: Mete
authors.initials: M
authors.lastname: Severcan
authors.forename: Feride
authors.initials: F
authors.lastname: Severcan
mesh_terms: D000818:Animals; D016000:Cluster Analysis; D005269:Femur / Q000187:drug effects; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects; D008297:Male; D016571:Neural Networks, Computer; D017433:Protein Structure, Secondary / Q000187:drug effects; D011506:Proteins / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000187:drug effects; D019821:Simvastatin / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013737:Testis / Q000187:drug effects; D013977:Tibia / Q000187:drug effects
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011506:Proteins; D019821:Simvastatin