title: The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery. An analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols.
authors.affiliation: Department of Orthopedic Oncology, Sarcoma Center Berlin-Brandenburg, Helios Klinikum Berlin-Buch, Academic Teaching Hospital of the Charité Universitätsmedizin, Berlin. Electronic address: dimosthenis.andreou@helios-kliniken.de.
authors.forename: D
authors.initials: D
authors.lastname: Andreou
authors.affiliation: Pediatrics 5-Oncology, Hematology and Immunology, COSS Study Center, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.
authors.forename: S S
authors.initials: SS
authors.lastname: Bielack
authors.affiliation: Pediatrics 5-Oncology, Hematology and Immunology, COSS Study Center, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Carrle
authors.affiliation: Pediatrics 5-Oncology, Hematology and Immunology, COSS Study Center, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Kevric
authors.affiliation: Department of Orthopedic Surgery, University Hospital of Vienna, Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Kotz
authors.affiliation: Department of General Orthopedics and Tumororthopedics, University Hospital of Muenster, Muenster, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Winkelmann
authors.affiliation: Department of Pathology, Universitätsspital Basel, Basel, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Jundt
authors.affiliation: Department of Pathology, Sarcoma Center Berlin-Brandenburg, Helios Klinikum Emil von Behring, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Werner
authors.affiliation: Department of Orthopedic Oncology, Sarcoma Center Berlin-Brandenburg, Helios Klinikum Berlin-Buch, Academic Teaching Hospital of the Charité Universitätsmedizin, Berlin.
authors.forename: S
authors.initials: S
authors.lastname: Fehlberg
authors.affiliation: Department of Hematology/Oncology, St Anna Children's Hospital, Vienna, Austria.
authors.forename: L
authors.initials: L
authors.lastname: Kager
authors.affiliation: Division of Oncology/Hematology, University Children's Hospital, Basel, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Kühne
authors.affiliation: Department of Pathology, University Hospital of Vienna, Vienna, Austria.
authors.forename: S
authors.initials: S
authors.lastname: Lang
authors.affiliation: Department of Orthopedic Surgery, University Hospital of Vienna, Vienna, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Dominkus
authors.affiliation: Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.
authors.forename: G U
authors.initials: GU
authors.lastname: Exner
authors.affiliation: Department of General Orthopedics and Tumororthopedics, University Hospital of Muenster, Muenster, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Hardes
authors.affiliation: Department of Orthopedics, Klinikum Ingolstadt, Ingolstadt.
authors.forename: A
authors.initials: A
authors.lastname: Hillmann
authors.affiliation: Department of Orthopedics and Traumatology, University Hospital of Heidelberg, Heidelberg.
authors.forename: V
authors.initials: V
authors.lastname: Ewerbeck
authors.affiliation: Department of Orthopedics, Albertinen Hospital, Hamburg.
authors.forename: U
authors.initials: U
authors.lastname: Heise
authors.affiliation: Department of Hematology, Oncology and Palliative Care, Sarcoma Center Berlin-Brandenburg, Helios Klinikum Bad Saarow, Academic Teaching Hospital of the Charité Universitätsmedizin, Bad Saarow, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Reichardt
authors.affiliation: Department of Orthopedic Oncology, Sarcoma Center Berlin-Brandenburg, Helios Klinikum Berlin-Buch, Academic Teaching Hospital of the Charité Universitätsmedizin, Berlin.
authors.forename: P-U
authors.initials: PU
authors.lastname: Tunn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000517:prevention & control*; D012516:Osteosarcoma / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult