title: Melanocortins protect against multiple organ dysfunction syndrome in mice.
authors.affiliation: Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Messina, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bitto
authors.forename: Francesca
authors.initials: F
authors.lastname: Polito
authors.forename: Domenica
authors.initials: D
authors.lastname: Altavilla
authors.forename: Natasha
authors.initials: N
authors.lastname: Irrera
authors.forename: Daniela
authors.initials: D
authors.lastname: Giuliani
authors.forename: Alessandra
authors.initials: A
authors.lastname: Ottani
authors.forename: Letteria
authors.initials: L
authors.lastname: Minutoli
authors.forename: Luca
authors.initials: L
authors.lastname: Spaccapelo
authors.forename: Maria
authors.initials: M
authors.lastname: Galantucci
authors.forename: Renzo
authors.initials: R
authors.lastname: Lodi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Guzzo
authors.forename: Salvatore
authors.initials: S
authors.lastname: Guarini
authors.forename: Francesco
authors.initials: F
authors.lastname: Squadrito
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005786:Gene Expression Regulation / Q000187:drug effects; D018836:Inflammation Mediators / Q000097:blood / Q000378:metabolism*; D016753:Interleukin-10 / Q000235:genetics / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008168:Lung / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D053486:Melanocortins / Q000378:metabolism*; D009074:Melanocyte-Stimulating Hormones / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D051379:Mice; D008810:Mice, Inbred C57BL; D009102:Multiple Organ Failure / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D018733:Nicotinic Antagonists / Q000494:pharmacology; D004369:Pentetic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D020011:Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D012333:RNA, Messenger / Q000378:metabolism; D011897:Random Allocation; D044105:Receptor, Melanocortin, Type 4 / Q000037:antagonists & inhibitors; D016019:Survival Analysis; D014409:Tumor Necrosis Factor-alpha / Q000097:blood / Q000235:genetics / Q000378:metabolism
chemical_list: C556062:IL10 protein, mouse; D018836:Inflammation Mediators; D053486:Melanocortins; D018733:Nicotinic Antagonists; D020011:Protective Agents; D012333:RNA, Messenger; D044105:Receptor, Melanocortin, Type 4; D014409:Tumor Necrosis Factor-alpha; C097943:alpha-MSH, DTPA-Nle(4)-Phe(7)-; D016753:Interleukin-10; D004369:Pentetic Acid; D009074:Melanocyte-Stimulating Hormones