The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease.
Douglas
Temple A
TA
Center for Applied Proteomics and Molecular Medicine, George Mason University, 10900 University Boulevard, Manassas, VA 20110, USA.
Tamburro
Davide
D
Fredolini
Claudia
C
Espina
Benjamin H
BH
Lepene
Benjamin S
BS
Ilag
Leopold
L
Espina
Virginia
V
Petricoin
Emanuel F
EF
Liotta
Lance A
LA
Luchini
Alessandra
A
D000818:Animals; D000880:Anthraquinones / Q000737:chemistry; D000942:Antigens, Bacterial / Q000652:urine*; D001672:Biocompatible Materials / Q000737:chemistry; D015415:Biomarkers; D025065:Borrelia burgdorferi / Q000737:chemistry; D004396:Coloring Agents / Q000737:chemistry; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D018884:Ixodes / Q000382:microbiology; D008193:Lyme Disease / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008422:Materials Testing; D015394:Molecular Structure; D010316:Particle Size
D000880:Anthraquinones; D000942:Antigens, Bacterial; D001672:Biocompatible Materials; D015415:Biomarkers; D004396:Coloring Agents; D020100:Hydrogels; C587874:acid black 48