PAOPA, a potent analogue of Pro-Leu-glycinamide and allosteric modulator of the dopamine D2 receptor, prevents NMDA receptor antagonist (MK-801)-induced deficits in social interaction in the rat: implications for the treatment of negative symptoms in schizophrenia.
Dyck
Bailee
B
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Guest
Kelly
K
Sookram
Christal
C
Basu
Dipannita
D
Johnson
Rodney
R
Mishra
Ram K
RK
D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004195:Disease Models, Animal; D016291:Dizocilpine Maleate / Q000633:toxicity; D004334:Drug Administration Schedule; D007398:Interpersonal Relations; D009075:MSH Release-Inhibiting Hormone / Q000031:analogs & derivatives*; D008297:Male; D011760:Pyrrolidinones / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012920:Social Behavior Disorders / Q000139:chemically induced / Q000517:prevention & control*
D011760:Pyrrolidinones; C067487:3-(N-prolylamine)-2-oxo-1-pyrrolidineacetamide; D016291:Dizocilpine Maleate; D009075:MSH Release-Inhibiting Hormone