title: Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.
authors.affiliation: Division of Molecular Genetics, Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, New York 10032, USA. GS2172@columbia.edu
authors.forename: George
authors.initials: G
authors.lastname: Stratigopoulos
authors.forename: Charles A
authors.initials: CA
authors.lastname: LeDuc
authors.forename: Maria L
authors.initials: ML
authors.lastname: Cremona
authors.forename: Wendy K
authors.initials: WK
authors.lastname: Chung
authors.forename: Rudolph L
authors.initials: RL
authors.lastname: Leibel
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism*; D000273:Adipose Tissue / Q000378:metabolism; D050154:Adiposity / Q000235:genetics; D000483:Alleles; D000071516:Alpha-Ketoglutarate-Dependent Dioxygenase FTO; D000818:Animals; D056668:Cathepsin L / Q000235:genetics / Q000378:metabolism; D045744:Cell Line, Tumor; D005786:Gene Expression Regulation; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism*; D007438:Introns / Q000235:genetics; D051379:Mice; D008817:Mice, Mutant Strains; D006899:Mixed Function Oxygenases; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D009765:Obesity / Q000235:genetics / Q000378:metabolism; D007652:Oxo-Acid-Lyases / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation / Q000235:genetics; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D054411:Receptors, Leptin / Q000235:genetics / Q000378:metabolism*; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism*; D020218:Response Elements; D012174:Retinitis Pigmentosa / Q000235:genetics / Q000378:metabolism; D050796:STAT3 Transcription Factor / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C000624101:Cux1 protein, mouse; C523257:Ftm protein, mouse; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D020033:Protein Isoforms; D054411:Receptors, Leptin; D012097:Repressor Proteins; D050796:STAT3 Transcription Factor; C494087:Stat3 protein, mouse; D006899:Mixed Function Oxygenases; C524916:FTO protein, mouse; D000071516:Alpha-Ketoglutarate-Dependent Dioxygenase FTO; D056668:Cathepsin L; C534278:Ctsl protein, mouse; D007652:Oxo-Acid-Lyases