Functional selectivity and biased receptor signaling.
Kenakin
Terry
T
Platform Technology Sciences, GlaxoSmithKline Research and Development, Research Triangle Park, NC 27709, USA. terry.p.kenakin@gsk.com
D000818:Animals; D019390:Arrestins / Q000502:physiology; D055808:Drug Discovery; D006801:Humans; D008024:Ligands; D011487:Protein Conformation; D011955:Receptors, Drug / Q000819:agonists / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D000071557:beta-Arrestins
D019390:Arrestins; D008024:Ligands; D011955:Receptors, Drug; D000071557:beta-Arrestins