title: Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.
authors.affiliation: Grupo de Modelagem Molecular de Sistemas Biológicos, Laboratório Nacional de Computação Científica, LNCC/MCT, Petrópolis, CEP 25651-075, Brazil. capriles@lncc.br
authors.forename: Priscila V S Z
authors.initials: PV
authors.lastname: Capriles
authors.forename: Ana C R
authors.initials: AC
authors.lastname: Guimarães
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Otto
authors.forename: Antonio B
authors.initials: AB
authors.lastname: Miranda
authors.forename: Laurent E
authors.initials: LE
authors.lastname: Dardenne
authors.forename: Wim M
authors.initials: WM
authors.lastname: Degrave
mesh_terms: D015094:3-Hydroxyacyl CoA Dehydrogenases / Q000378:metabolism; D000595:Amino Acid Sequence; D000977:Antiparasitic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D014355:Chagas Disease / Q000188:drug therapy* / Q000469:parasitology; D030562:Databases, Protein; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015800:Protozoan Proteins / Q000737:chemistry* / Q000145:classification / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D040681:Structural Homology, Protein; D014349:Trypanosoma cruzi / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*
chemical_list: D000977:Antiparasitic Agents; D015800:Protozoan Proteins; D015094:3-Hydroxyacyl CoA Dehydrogenases