Hypotonic swelling-induced activation of PKN1 mediates cell survival in cardiac myocytes.
Kajimoto
Katsuya
K
Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA.
Shao
Dan
D
Takagi
Hiromitsu
H
Maceri
Gregorio
G
Zablocki
Daniela
D
Mukai
Hideyuki
H
Ono
Yoshitaka
Y
Sadoshima
Junichi
J
D000704:Analysis of Variance; D000818:Animals; D015153:Blotting, Western; D049108:Cell Enlargement / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology*; D002478:Cells, Cultured; D015536:Down-Regulation / Q000187:drug effects / Q000502:physiology; D007038:Hypotonic Solutions / Q000494:pharmacology; D047468:Immunoprecipitation; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000378:metabolism*; D010766:Phosphorylation / Q000187:drug effects / Q000502:physiology; D011493:Protein Kinase C / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology
D007038:Hypotonic Solutions; C061570:protein kinase N; D011493:Protein Kinase C; D020928:Mitogen-Activated Protein Kinases