title: Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig.
authors.affiliation: Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA. armsteaw@uphs.upenn.edu
authors.forename: William M
authors.initials: WM
authors.lastname: Armstead
authors.forename: Kumkum
authors.initials: K
authors.lastname: Ganguly
authors.forename: John
authors.initials: J
authors.lastname: Riley
authors.forename: J Willis
authors.initials: JW
authors.lastname: Kiessling
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Cines
authors.forename: Abd A R
authors.initials: AA
authors.lastname: Higazi
authors.forename: Sergei
authors.initials: S
authors.lastname: Zaitsev
authors.forename: Vladimir R
authors.initials: VR
authors.lastname: Muzykantov
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000098:blood supply*; D004912:Erythrocytes / Q000378:metabolism*; D048031:JNK Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors*; D011446:Prospective Studies; D011897:Random Allocation; D010959:Tissue Plasminogen Activator / Q000494:pharmacology*; D016781:Toxoplasmosis, Cerebral / Q000503:physiopathology*; D014664:Vasodilation / Q000187:drug effects*; D048051:p38 Mitogen-Activated Protein Kinases / Q000187:drug effects*
chemical_list: D048031:JNK Mitogen-Activated Protein Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D010959:Tissue Plasminogen Activator