NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death.
Poddar
Ranjana
R
University of New Mexico Health Sciences Center, Department of Neurology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Deb
Ishani
I
Mukherjee
Saibal
S
Paul
Surojit
S
D000818:Animals; D016923:Cell Death / Q000502:physiology; D002478:Cells, Cultured; D005260:Female; D018698:Glutamic Acid / Q000633:toxicity*; D006367:HeLa Cells; D006801:Humans; D009474:Neurons / Q000201:enzymology*; D011247:Pregnancy; D054558:Protein Tyrosine Phosphatases, Non-Receptor / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology*
C121001:NR2B NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid; D054558:Protein Tyrosine Phosphatases, Non-Receptor; C489931:Ptpn5 protein, rat