PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice.
Garlapati
Srinivas
S
Vaccine and Infectious Disease Organization, University of Saskatchewan, 120 Veterinary Road, Saskatoon S7N 5E3, Canada.
Eng
Nelson F
NF
Wilson
Heather L
HL
Buchanan
Rachelle
R
Mutwiri
George K
GK
Babiuk
Lorne A
LA
Gerdts
Volker
V
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000818:Animals; D004337:Drug Carriers; D007074:Immunoglobulin G / Q000097:blood; D007279:Injections, Subcutaneous; D008198:Lymph Nodes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008863:Microspheres; D009838:Oligodeoxyribonucleotides / Q000008:administration & dosage*; D009943:Organophosphorus Compounds / Q000008:administration & dosage*; D010047:Ovalbumin / Q000276:immunology*; D011108:Polymers / Q000008:administration & dosage*; D018417:Th1 Cells / Q000276:immunology*; D051598:Whole Body Imaging / Q000379:methods
D000276:Adjuvants, Immunologic; C408982:CPG-oligonucleotide; D004337:Drug Carriers; D007074:Immunoglobulin G; D009838:Oligodeoxyribonucleotides; D009943:Organophosphorus Compounds; D011108:Polymers; C546078:poly(di(carboxylatophenoxy)phosphazene); D010047:Ovalbumin