Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
Liu
Yan Long
YL
Department of Colorectal Surgery, the Affiliated Tumor Hospital, Harbin Medical University, Harbin, China.
Yang
Yan Mei
YM
Xu
Hui
H
Dong
Xin Shu
XS
D002277:Carcinoma / Q000201:enzymology* / Q000235:genetics / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000201:enzymology* / Q000235:genetics / Q000601:surgery*; D018450:Disease Progression; D018572:Disease-Free Survival; D010450:Endopeptidases / Q000235:genetics / Q000378:metabolism*; D005260:Female; D015870:Gene Expression; D016259:Genes, myc / Q000235:genetics; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D009687:Nuclear Proteins / Q000235:genetics; D063150:Polycomb Repressive Complex 1; D011379:Prognosis; D016016:Proportional Hazards Models; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000235:genetics; D013869:Thiolester Hydrolases / Q000235:genetics / Q000378:metabolism*; D017211:Treatment Failure; D043222:Ubiquitin Thiolesterase; D064570:Ubiquitin-Specific Proteases; D015854:Up-Regulation
C069077:BMI1 protein, human; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D012333:RNA, Messenger; D012097:Repressor Proteins; D063150:Polycomb Repressive Complex 1; D013869:Thiolester Hydrolases; D010450:Endopeptidases; D043222:Ubiquitin Thiolesterase; D064570:Ubiquitin-Specific Proteases; C527170:Usp22 protein, human