Thrombin promotes human lung fibroblasts to proliferate via NADPH oxidase/reactive oxygen species/extracellular regulated kinase signaling pathway.
Zhou
Sheng-yu
SY
Department of Respiratory Diseases, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China.
Xiao
Wei
W
Pan
Xiu-jie
XJ
Zhu
Mao-xiang
MX
Yang
Zhi-hua
ZH
Zheng
Chun-yan
CY
D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D048049:Extracellular Signal-Regulated MAP Kinases / Q000032:analysis / Q000502:physiology*; D005347:Fibroblasts / Q000187:drug effects / Q000502:physiology; D005434:Flow Cytometry; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000166:cytology; D019255:NADPH Oxidases / Q000032:analysis / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D013917:Thrombin / Q000494:pharmacology*
D017382:Reactive Oxygen Species; D019255:NADPH Oxidases; D048049:Extracellular Signal-Regulated MAP Kinases; D013917:Thrombin; D005978:Glutathione