Triamcinolone-loaded glutaraldehyde cross-linked chitosan microspheres: prolonged release approach for the treatment of rheumatoid arthritis.
Dhanaraju
Magharla Dasaratha
MD
Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533 294, India. mddhanaraju@yahoo.com
Elizabeth
Sheela
S
Gunasekaran
Thirumurugan
T
D000818:Animals; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000473:pathology; D002152:Calorimetry, Differential Scanning; D048271:Chitosan / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000737:chemistry; D005976:Glutaral / Q000737:chemistry; D008297:Male; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D051381:Rats; D017208:Rats, Wistar; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014221:Triamcinolone / Q000008:administration & dosage* / Q000494:pharmacology
D003432:Cross-Linking Reagents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D005938:Glucocorticoids; D014221:Triamcinolone; D048271:Chitosan; D005976:Glutaral