Protective effect of phloroglucinol against myocardial ischaemia-reperfusion injury is related to inhibition of myeloperoxidase activity and inflammatory cell infiltration.
Li
Ting-Ting
TT
Department of Pharmacology, Central South University, Changsha, China.
Zhang
Yi-Shuai
YS
He
Lan
L
Li
Nian-Sheng
NS
Peng
Jun
J
Li
Yuan-Jian
YJ
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D002316:Cardiotonic Agents / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000494:pharmacology; D007249:Inflammation / Q000276:immunology; D008297:Male; D009203:Myocardial Infarction / Q000473:pathology; D015428:Myocardial Reperfusion Injury / Q000276:immunology / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D009206:Myocardium / Q000473:pathology; D020556:Neutrophil Infiltration / Q000187:drug effects* / Q000502:physiology; D009195:Peroxidase / Q000037:antagonists & inhibitors*; D010696:Phloroglucinol / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D002316:Cardiotonic Agents; D004791:Enzyme Inhibitors; D010696:Phloroglucinol; D009195:Peroxidase