title: A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells.
authors.affiliation: Institute of Medicinal Chemistry, Sun Yat-sen University, Guangzhou 510006, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Wu
authors.forename: Xi-Wei
authors.initials: XW
authors.lastname: Wu
authors.forename: Keli
authors.initials: K
authors.lastname: Agama
authors.forename: Yves
authors.initials: Y
authors.lastname: Pommier
authors.forename: Jun
authors.initials: J
authors.lastname: Du
authors.forename: Ding
authors.initials: D
authors.lastname: Li
authors.forename: Lian-Quan
authors.initials: LQ
authors.lastname: Gu
authors.forename: Zhi-Shu
authors.initials: ZS
authors.lastname: Huang
authors.forename: Lin-Kun
authors.initials: LK
authors.lastname: An
mesh_terms: D002166:Camptothecin / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D006801:Humans; D007212:Indolizines / Q000494:pharmacology*; D020014:K562 Cells; D015363:Quinolones / Q000494:pharmacology*; D059004:Topoisomerase I Inhibitors / Q000494:pharmacology*
chemical_list: D007212:Indolizines; D015363:Quinolones; D059004:Topoisomerase I Inhibitors; C554566:ethyl 7-fluoro-5,12-dioxo-5,12-dihydroindolizino(2,3-g)quinoline-6-carboxylate; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin