Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.
Ta
V B T
VB
Department of Pulmonary Medicine, Erasmus MC Rotterdam, Rotterdam, The Netherlands.
de Haan
A B
AB
de Bruijn
M J W
MJ
Dingjan
G M
GM
Hendriks
R W
RW
D048868:Adaptor Proteins, Signal Transducing / Q000502:physiology*; D000077329:Agammaglobulinaemia Tyrosine Kinase; D000818:Animals; D018398:Homeodomain Proteins / Q000502:physiology; D007133:Immunoglobulin Joining Region / Q000235:genetics; D007147:Immunoglobulin Light Chains / Q000235:genetics; D007135:Immunoglobulin Variable Region / Q000235:genetics; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D054420:Pre-B Cell Receptors / Q000502:physiology; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology* / Q000276:immunology; D011505:Protein-Tyrosine Kinases / Q000502:physiology*; D011995:Recombination, Genetic
D048868:Adaptor Proteins, Signal Transducing; C113939:B cell linker protein; D018398:Homeodomain Proteins; D007133:Immunoglobulin Joining Region; D007147:Immunoglobulin Light Chains; D007135:Immunoglobulin Variable Region; D054420:Pre-B Cell Receptors; C064658:RAG-1 protein; D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase; C000625951:Btk protein, mouse