Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering.
Hamad
Islam
I
Molecular Targeting and Polymer Toxicology Group, School of Pharmacy, University of Brighton, Brighton BN2 4GJ, U.K.
Al-Hanbali
Othman
O
Hunter
A Christy
AC
Rutt
Kenneth J
KJ
Andresen
Thomas L
TL
Moghimi
S Moein
SM
D000327:Adsorption; D000818:Animals; D003167:Complement Activation / Q000187:drug effects*; D004738:Engineering / Q000379:methods*; D005029:Ethylenediamines / Q000737:chemistry; D006801:Humans; D037102:Lectins / Q000378:metabolism; D008297:Male; D054118:Nanospheres / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D044967:Serum / Q000187:drug effects / Q000276:immunology*; D013329:Structure-Activity Relationship
D005029:Ethylenediamines; D037102:Lectins; C012571:tetronic 701; D011092:Polyethylene Glycols