Oleic acid ameliorates amyloidosis in cellular and mouse models of Alzheimer's disease.
Amtul
Zareen
Z
Department of Biochemistry, University of Western Ontario, London, ON, Canada. zamtul@uwo.ca
Westaway
David
D
Cechetto
David F
DF
Rozmahel
Richard F
RF
D000544:Alzheimer Disease / Q000378:metabolism*; D053829:Amyloid Precursor Protein Secretases / Q000187:drug effects / Q000378:metabolism; D016564:Amyloid beta-Protein Precursor / Q000187:drug effects / Q000378:metabolism*; D000686:Amyloidosis / Q000378:metabolism / Q000517:prevention & control*; D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000187:drug effects / Q000378:metabolism; D002478:Cells, Cultured; D004041:Dietary Fats / Q000378:metabolism; D004195:Disease Models, Animal; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008818:Mice, Neurologic Mutants; D008822:Mice, Transgenic; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000378:metabolism*; D019301:Oleic Acid / Q000008:administration & dosage / Q000378:metabolism*; D010446:Peptide Fragments; D058225:Plaque, Amyloid / Q000378:metabolism / Q000517:prevention & control; D053763:Presenilins / Q000187:drug effects / Q000378:metabolism
D016564:Amyloid beta-Protein Precursor; C509285:Bace2 protein, mouse; D004041:Dietary Fats; D018696:Neuroprotective Agents; D010446:Peptide Fragments; D053763:Presenilins; D019301:Oleic Acid; D053829:Amyloid Precursor Protein Secretases; D016282:Aspartic Acid Endopeptidases