Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice.
Ikemura
Mai
M
Department of Drug Delivery Research and Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, and Institute for Integrated Cell-Material Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Nishikawa
Makiya
M
Hyoudou
Kenji
K
Kobayashi
Yuki
Y
Yamashita
Fumiyoshi
F
Hashida
Mitsuru
M
D041721:3T3-L1 Cells; D000818:Animals; D001835:Body Weight; D002374:Catalase / Q000008:administration & dosage / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006861:Hydrogen Peroxide / Q000378:metabolism*; D007333:Insulin Resistance; D008054:Lipid Peroxides / Q000032:analysis; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008820:Mice, Obese; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000378:metabolism*
D008054:Lipid Peroxides; C070295:catalase-polyethylene glycol; D011092:Polyethylene Glycols; D006861:Hydrogen Peroxide; D002374:Catalase