DNAzyme-like activity of hemin-telomeric G-quadruplexes for the optical analysis of telomerase and its inhibitors.
Freeman
Ronit
R
Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Sharon
Etery
E
Teller
Carsten
C
Henning
Anja
A
Tzfati
Yehuda
Y
Willner
Itamar
I
D062365:Aminobenzoates / Q000494:pharmacology; D001483:Base Sequence; D055162:Biocatalysis / Q000187:drug effects; D002478:Cells, Cultured; D021881:DNA, Catalytic / Q000737:chemistry / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology; D054856:G-Quadruplexes; D057809:HEK293 Cells; D006427:Hemin / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D016015:Logistic Models; D018625:Microscopy, Atomic Force; D009281:Naphthalenes / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D019098:Telomerase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D016615:Telomere / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D013997:Time Factors
D062365:Aminobenzoates; C458523:BIBR 1532; D021881:DNA, Catalytic; D004791:Enzyme Inhibitors; D009281:Naphthalenes; D006427:Hemin; D019098:Telomerase