Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.
Salinthone
Sonemany
S
Portland Veterans Affairs Medical Center, Portland, OR 97239, USA; Department of Neurology, Oregon Health and Sciences University, Portland, OR 97239, USA.
Schillace
Robynn V
RV
Tsang
Catherine
C
Regan
John W
JW
Bourdette
Dennis N
DN
Carr
Daniel W
DW
D000067956:Adenylyl Cyclase Inhibitors; D000262:Adenylyl Cyclases / Q000378:metabolism; D020013:Calcium Signaling / Q000187:drug effects; D000242:Cyclic AMP / Q000096:biosynthesis*; D015232:Dinoprostone / Q000494:pharmacology; D004533:Egtazic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D057809:HEK293 Cells; D006801:Humans; D007694:Killer Cells, Natural; D007963:Leukocytes, Mononuclear / Q000187:drug effects; D043562:Receptors, G-Protein-Coupled / Q000502:physiology*; D058307:Receptors, Prostaglandin E, EP2 Subtype / Q000378:metabolism; D058309:Receptors, Prostaglandin E, EP4 Subtype / Q000378:metabolism; D008063:Thioctic Acid / Q000031:analogs & derivatives / Q000494:pharmacology*
D000067956:Adenylyl Cyclase Inhibitors; D043562:Receptors, G-Protein-Coupled; D058307:Receptors, Prostaglandin E, EP2 Subtype; D058309:Receptors, Prostaglandin E, EP4 Subtype; D004533:Egtazic Acid; D008063:Thioctic Acid; C015144:dihydrolipoic acid; C013091:lipoamide; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; C025603:1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; D015232:Dinoprostone