Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease.
Fitch
Paul M
PM
MRC Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK. pfitch@staffmail.ed.ac.uk
Howie
Sarah E M
SE
Wallace
William A H
WA
D000328:Adult; D000368:Aged; D015153:Blotting, Western; D004847:Epithelial Cells / Q000378:metabolism* / Q000473:pathology; D005260:Female; D053823:Hedgehog Proteins / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D017563:Lung Diseases, Interstitial / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D020545:Respiratory Mucosa / Q000378:metabolism / Q000473:pathology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000502:physiology; D019063:Tenascin / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000378:metabolism*
D053823:Hedgehog Proteins; C509239:SHH protein, human; D019063:Tenascin; D016212:Transforming Growth Factor beta