title: Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cδ/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages.
authors.affiliation: Department of Cardiology, Xinhua Hospital, Shanghai Jiaotong University Medical School, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhou-Qing
authors.initials: ZQ
authors.lastname: Huang
authors.forename: Chang-Qian
authors.initials: CQ
authors.lastname: Wang
authors.forename: Lian-Sheng
authors.initials: LS
authors.lastname: Wang
authors.forename: Shu
authors.initials: S
authors.lastname: Meng
authors.forename: Ya-Chen
authors.initials: YC
authors.lastname: Zhang
authors.forename: Ting
authors.initials: T
authors.lastname: Chen
authors.forename: Yu-Qi
authors.initials: YQ
authors.lastname: Fan
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D037621:Artemisinins / Q000494:pharmacology*; D051926:Basigin / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D015536:Down-Regulation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism / Q000502:physiology*; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D020935:MAP Kinase Signaling System / Q000187:drug effects / Q000502:physiology; D008264:Macrophages / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D020780:Matrix Metalloproteinase 9 / Q000235:genetics / Q000378:metabolism; D061965:Matrix Metalloproteinase Inhibitors; D051745:Protein Kinase C-delta / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000187:drug effects; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism / Q000502:physiology*
chemical_list: D000890:Anti-Infective Agents; D037621:Artemisinins; C497886:BSG protein, human; D061965:Matrix Metalloproteinase Inhibitors; D051926:Basigin; C031327:artemisinin; D051745:Protein Kinase C-delta; D048049:Extracellular Signal-Regulated MAP Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D020780:Matrix Metalloproteinase 9; D013755:Tetradecanoylphorbol Acetate