A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma.
Avery
Lindsay B
LB
Department of Pharmacology and Molecular Sciences, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Osler 527, Baltimore, MD 21287, USA. lavery2@jhmi.edu
Parsons
Teresa L
TL
Meyers
David J
DJ
Hubbard
Walter C
WC
D000480:Alkynes; D019380:Anti-HIV Agents / Q000032:analysis / Q000097:blood / Q000737:chemistry; D048588:Benzoxazines / Q000032:analysis* / Q000097:blood* / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003521:Cyclopropanes; D004355:Drug Stability; D006801:Humans; D016018:Least-Squares Analysis; D015203:Reproducibility of Results; D012661:Semen / Q000737:chemistry*; D012680:Sensitivity and Specificity; D053719:Tandem Mass Spectrometry / Q000379:methods*
D000480:Alkynes; D019380:Anti-HIV Agents; D048588:Benzoxazines; D003521:Cyclopropanes; C098320:efavirenz