title: TS, DHFR and GARFT expression in non-squamous cell carcinoma of NSCLC and malignant pleural mesothelioma patients treated with pemetrexed.
authors.affiliation: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu, Japan. hidetaka@med.uoeh-u.ac.jp
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Uramoto
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Onitsuka
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Shimokawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hanagiri
mesh_terms: D000328:Adult; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000201:enzymology; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D005971:Glutamates / Q000008:administration & dosage / Q000627:therapeutic use*; D006147:Guanine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy* / Q000201:enzymology; D008875:Middle Aged; D000068437:Pemetrexed; D051026:Phosphoribosylglycinamide Formyltransferase / Q000096:biosynthesis / Q000235:genetics; D010997:Pleural Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D013762:Tetrahydrofolate Dehydrogenase / Q000096:biosynthesis / Q000235:genetics; D013940:Thymidylate Synthase / Q000096:biosynthesis / Q000235:genetics; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D005971:Glutamates; D012333:RNA, Messenger; D000068437:Pemetrexed; D006147:Guanine; D016190:Carboplatin; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D051026:Phosphoribosylglycinamide Formyltransferase; D002945:Cisplatin