title: BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities.
authors.affiliation: Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Taiwan.
authors.forename: Chih-Bo
authors.initials: CB
authors.lastname: Hu
authors.forename: Ching-Ping
authors.initials: CP
authors.lastname: Chen
authors.forename: Teng-Kuang
authors.initials: TK
authors.lastname: Yeh
authors.forename: Jen-Shin
authors.initials: JS
authors.lastname: Song
authors.forename: Chi-Yen
authors.initials: CY
authors.lastname: Chang
authors.forename: Jiunn-Jye
authors.initials: JJ
authors.lastname: Chuu
authors.forename: Fei-Feng
authors.initials: FF
authors.lastname: Tung
authors.forename: Pei-Yin
authors.initials: PY
authors.lastname: Ho
authors.forename: Tung-Wei
authors.initials: TW
authors.lastname: Chen
authors.forename: Chi-Hung
authors.initials: CH
authors.lastname: Lin
authors.forename: Min-Hsien
authors.initials: MH
authors.lastname: Wang
authors.forename: Kai-Yen
authors.initials: KY
authors.lastname: Chang
authors.forename: Chen-Lung
authors.initials: CL
authors.lastname: Huang
authors.forename: Heng-Liang
authors.initials: HL
authors.lastname: Lin
authors.forename: Wen-Tai
authors.initials: WT
authors.lastname: Li
authors.forename: Der-Ren
authors.initials: DR
authors.lastname: Hwang
authors.forename: Jyh-Haur
authors.initials: JH
authors.lastname: Chern
authors.forename: Ling-Ling
authors.initials: LL
authors.lastname: Hwang
authors.forename: Jang-Yang
authors.initials: JY
authors.lastname: Chang
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Chao
authors.forename: Chiung-Tong
authors.initials: CT
authors.lastname: Chen
mesh_terms: D000284:Administration, Oral; D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D050256:Antimitotic Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D002453:Cell Cycle / Q000187:drug effects; D045744:Cell Line, Tumor; D004285:Dogs; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D007942:Leukemia, Experimental / Q000188:drug therapy; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008870:Microtubules / Q000737:chemistry / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D013844:Thiazoles / Q000494:pharmacology*
chemical_list: D020533:Angiogenesis Inhibitors; D050256:Antimitotic Agents; D000970:Antineoplastic Agents; D007211:Indoles; C555061:N-(3-methyl-5-isothiazolyl)-2-1-((3-methyl-5-isoxazolyl)methyl)-1H-3-indolyl-2-oxoacetamide; D013844:Thiazoles