title: Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens.
authors.affiliation: IBMP -Institute for Biomedical and Pharmaceutical Research, Paul-Ehrlich-Str. 19, D-90562 Nürnberg-Heroldsberg, Germany.
authors.forename: Jürgen B
authors.initials: JB
authors.lastname: Bulitta
authors.forename: Martina
authors.initials: M
authors.lastname: Kinzig
authors.forename: Verena
authors.initials: V
authors.lastname: Jakob
authors.forename: Ulrike
authors.initials: U
authors.lastname: Holzgrabe
authors.forename: Fritz
authors.initials: F
authors.lastname: Sörgel
authors.forename: Nicholas H G
authors.initials: NH
authors.lastname: Holford
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008657:Metabolic Clearance Rate; D015233:Models, Statistical; D009010:Monte Carlo Method; D010878:Piperacillin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D010878:Piperacillin