A batch modelling approach to monitor a freeze-drying process using in-line Raman spectroscopy.
Sarraguça
Mafalda Cruz
MC
REQUIMTE, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua Aníbal Cunha 164, 4099-030 Porto, Portugal.
De Beer
Thomas
T
Vervaet
Chris
C
Remon
Jean-Paul
JP
Lopes
João Almeida
JA
D005612:Freeze Drying / Q000379:methods*; D016018:Least-Squares Analysis; D008353:Mannitol / Q000737:chemistry*; D008956:Models, Chemical; D013059:Spectrum Analysis, Raman / Q000379:methods
D008353:Mannitol