Piperine, active substance of black pepper, alleviates hypertension induced by NO synthase inhibition.
Hlavackova
L
L
Department of Pathology, Faculty of Medicine, Comenus University, Bratislava, Slovakia.
Urbanova
A
A
Ulicna
O
O
Janega
P
P
Cerna
A
A
Babal
P
P
D000470:Alkaloids / Q000627:therapeutic use*; D000818:Animals; D000906:Antibodies / Q000378:metabolism; D001013:Aorta, Thoracic / Q000378:metabolism / Q000473:pathology; D052117:Benzodioxoles / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D004549:Elastin / Q000378:metabolism; D006973:Hypertension / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D008297:Male; D019331:NG-Nitroarginine Methyl Ester; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000276:immunology; D029222:Piper nigrum; D010880:Piperidines / Q000627:therapeutic use*; D053284:Polyunsaturated Alkamides / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D000470:Alkaloids; D000906:Antibodies; D052117:Benzodioxoles; D010880:Piperidines; D053284:Polyunsaturated Alkamides; D004549:Elastin; D019001:Nitric Oxide Synthase; C008922:piperine; D019331:NG-Nitroarginine Methyl Ester