title: Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis.
authors.affiliation: Department of Hematology and Immunology, Kanazawa Medical University, Kahoku-gun, Ishikawa, Japan.
authors.forename: Yan
authors.initials: Y
authors.lastname: Cao
authors.forename: Zhe-Xiong
authors.initials: ZX
authors.lastname: Jin
authors.forename: Xiao-Peng
authors.initials: XP
authors.lastname: Tong
authors.forename: Sun
authors.initials: S
authors.lastname: Yue
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Sakai
authors.forename: Takafumi
authors.initials: T
authors.lastname: Kawanami
authors.forename: Toshioki
authors.initials: T
authors.lastname: Sawaki
authors.forename: Miyuki
authors.initials: M
authors.lastname: Miki
authors.forename: Haruka
authors.initials: H
authors.lastname: Iwao
authors.forename: Akio
authors.initials: A
authors.lastname: Nakajima
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Masaki
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Fukushima
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Fujita
authors.forename: Hideo
authors.initials: H
authors.lastname: Nakajima
authors.forename: Toshiro
authors.initials: T
authors.lastname: Okazaki
authors.forename: Hisanori
authors.initials: H
authors.lastname: Umehara
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D064007:Ataxia Telangiectasia Mutated Proteins; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000494:pharmacology; D053148:Caspase 3 / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000378:metabolism; D045744:Cell Line, Tumor; D000071877:Checkpoint Kinase 1; D004268:DNA-Binding Proteins / Q000378:metabolism; D004357:Drug Synergism; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D000077146:Irinotecan; D016399:Lymphoma, T-Cell / Q000188:drug therapy / Q000201:enzymology / Q000276:immunology / Q000473:pathology; D051379:Mice; D011494:Protein Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D059004:Topoisomerase I Inhibitors / Q000494:pharmacology*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D025521:Tumor Suppressor Proteins / Q000378:metabolism; D019014:fas Receptor / Q000235:genetics / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D059004:Topoisomerase I Inhibitors; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; D019014:fas Receptor; D000077146:Irinotecan; D011494:Protein Kinases; C576324:ATM protein, human; D064007:Ataxia Telangiectasia Mutated Proteins; C576325:Atm protein, mouse; C000605867:CHEK1 protein, human; D000071877:Checkpoint Kinase 1; C000605869:Chek1 protein, mouse; D017346:Protein Serine-Threonine Kinases; D053148:Caspase 3; D002166:Camptothecin