title: Effects on molecular conformation and anticoagulant activities of 1,6-anhydrosugars at the reducing terminal of antithrombin-binding octasaccharides isolated from low-molecular-weight heparin enoxaparin.
authors.affiliation: G. Ronzoni Institute for Chemical and Biochemical Research, via G. Colombo 81, 20133 Milan, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Guerrini
authors.forename: Stefano
authors.initials: S
authors.lastname: Elli
authors.forename: Davide
authors.initials: D
authors.lastname: Gaudesi
authors.forename: Giangiacomo
authors.initials: G
authors.lastname: Torri
authors.forename: Benito
authors.initials: B
authors.lastname: Casu
authors.forename: Pierre
authors.initials: P
authors.lastname: Mourier
authors.forename: Frederic
authors.initials: F
authors.lastname: Herman
authors.forename: Christian
authors.initials: C
authors.lastname: Boudier
authors.forename: Martin
authors.initials: M
authors.lastname: Lorenz
authors.forename: Christian
authors.initials: C
authors.lastname: Viskov
mesh_terms: D000925:Anticoagulants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D058833:Antithrombin Proteins / Q000737:chemistry* / Q000378:metabolism; D002240:Carbohydrate Sequence; D017984:Enoxaparin / Q000737:chemistry*; D015951:Factor Xa / Q000737:chemistry; D065427:Factor Xa Inhibitors; D006595:Hexosamines / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D056004:Molecular Dynamics Simulation; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011485:Protein Binding; D013329:Structure-Activity Relationship
chemical_list: D000925:Anticoagulants; D058833:Antithrombin Proteins; D017984:Enoxaparin; D065427:Factor Xa Inhibitors; D006595:Hexosamines; D009844:Oligosaccharides; D015951:Factor Xa