Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.
Qian
Yong
Y
Nanjing University, People's Republic of China.
Zhang
Hong-Jia
HJ
Lv
Peng-Cheng
PC
Zhu
Hai-Liang
HL
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D045744:Cell Line, Tumor; D002599:Chalcone / Q000737:chemistry; D003198:Computer Simulation; D019791:Guanidine / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008958:Models, Molecular; D013329:Structure-Activity Relationship; D014404:Tubulin / Q000737:chemistry* / Q000378:metabolism; D050257:Tubulin Modulators / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000970:Antineoplastic Agents; D014404:Tubulin; D050257:Tubulin Modulators; D002599:Chalcone; D019791:Guanidine