CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.
Rakhra
Kavya
K
Division of Oncology, Departments of Medicine, Pathology and Molecular Imaging, Stanford University School of Medicine, Stanford, CA 94305, USA.
Bachireddy
Pavan
P
Zabuawala
Tahera
T
Zeiser
Robert
R
Xu
Liwen
L
Kopelman
Andrew
A
Fan
Alice C
AC
Yang
Qiwei
Q
Braunstein
Lior
L
Crosby
Erika
E
Ryeom
Sandra
S
Felsher
Dean W
DW
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D049109:Cell Proliferation / Q000187:drug effects; D016922:Cellular Senescence / Q000187:drug effects; D018925:Chemokines / Q000235:genetics / Q000378:metabolism; D016572:Cyclosporine / Q000494:pharmacology; D016044:Fusion Proteins, bcr-abl / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic; D020868:Gene Silencing; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007942:Leukemia, Experimental / Q000235:genetics / Q000276:immunology; D051379:Mice; D008822:Mice, Transgenic; D009369:Neoplasms / Q000235:genetics / Q000276:immunology / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000235:genetics / Q000276:immunology; D009857:Oncogenes / Q000235:genetics*; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics; D012074:Remission Induction; D019700:Thrombospondin 1 / Q000235:genetics / Q000378:metabolism; D059016:Tumor Microenvironment / Q000187:drug effects / Q000235:genetics / Q000276:immunology*
D018925:Chemokines; D007166:Immunosuppressive Agents; D016271:Proto-Oncogene Proteins c-myc; D019700:Thrombospondin 1; D016572:Cyclosporine; D016044:Fusion Proteins, bcr-abl