Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases.
Gollapalli
Deviprasad R
DR
Department of Biology, Brandeis University, 415 South Street, Waltham, MA 02454-9110, USA.
Macpherson
Iain S
IS
Liechti
George
G
Gorla
Suresh Kumar
SK
Goldberg
Joanna B
JB
Hedstrom
Lizbeth
L
D001665:Binding Sites; D025065:Borrelia burgdorferi / Q000187:drug effects / Q000201:enzymology; D003198:Computer Simulation; D016785:Cryptosporidium parvum / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors* / Q000145:classification / Q000378:metabolism; D007700:Kinetics; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D013297:Streptococcus pyogenes / Q000187:drug effects / Q000201:enzymology
D004791:Enzyme Inhibitors; D011994:Recombinant Proteins; D007168:IMP Dehydrogenase