Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD.
Wen
Yudong
Y
Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia.
Reid
David W
DW
Zhang
Dongcheng
D
Ward
Chris
C
Wood-Baker
Richard
R
Walters
E Haydn
EH
D000368:Aged; D001706:Biopsy; D001980:Bronchi / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000276:immunology*; D001999:Bronchoscopy; D003430:Cross-Sectional Studies; D004804:Eosinophils / Q000276:immunology; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D018836:Inflammation Mediators / Q000032:analysis; D016209:Interleukin-8 / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008407:Mast Cells / Q000276:immunology; D008450:Maximal Midexpiratory Flow Rate; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology; D011014:Pneumonia / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D029424:Pulmonary Disease, Chronic Obstructive / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D013183:Sputum / Q000166:cytology / Q000276:immunology*; D013648:Tasmania; D014797:Vital Capacity
C508606:CXCL8 protein, human; D018836:Inflammation Mediators; D016209:Interleukin-8
BAL; airway cellularity; current smokers; endobronchial biopsies; ex-smokers; sputum