title: Activation of phosphatidylinositol 3-kinase/Akt and impairment of nuclear factor-kappaB: molecular mechanisms behind the arrested maturation/activation state of Leishmania infantum-infected dendritic cells.
authors.affiliation: Faculdade de Farmácia, and Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Coimbra, Portugal. neves_bruno@sapo.pt
authors.forename: Bruno Miguel
authors.initials: BM
authors.lastname: Neves
authors.forename: Ricardo
authors.initials: R
authors.lastname: Silvestre
authors.forename: Mariana
authors.initials: M
authors.lastname: Resende
authors.forename: Ali
authors.initials: A
authors.lastname: Ouaissi
authors.forename: Joana
authors.initials: J
authors.lastname: Cunha
authors.forename: Joana
authors.initials: J
authors.lastname: Tavares
authors.forename: Inês
authors.initials: I
authors.lastname: Loureiro
authors.forename: Nuno
authors.initials: N
authors.lastname: Santarém
authors.forename: Ana Marta
authors.initials: AM
authors.lastname: Silva
authors.forename: Maria Celeste
authors.initials: MC
authors.lastname: Lopes
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Cruz
authors.forename: Anabela
authors.initials: A
authors.lastname: Cordeiro da Silva
mesh_terms: D000818:Animals; D002453:Cell Cycle / Q000276:immunology / Q000502:physiology; D002454:Cell Differentiation / Q000276:immunology; D002478:Cells, Cultured; D003713:Dendritic Cells / Q000276:immunology* / Q000378:metabolism / Q000473:pathology / Q000502:physiology; D015536:Down-Regulation / Q000235:genetics / Q000502:physiology; D004789:Enzyme Activation / Q000502:physiology; D005260:Female; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D057131:Immune Evasion / Q000276:immunology / Q000502:physiology; D018314:Leishmania infantum / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D007898:Leishmaniasis, Visceral / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D030781:Organisms, Genetically Modified; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism* / Q000502:physiology; D051057:Proto-Oncogene Proteins c-akt / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology
chemical_list: D016328:NF-kappa B; D049452:Green Fluorescent Proteins; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt