title: Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.
authors.affiliation: Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Tonia J
authors.initials: TJ
authors.lastname: Buchholz
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Rath
authors.forename: Nicole B
authors.initials: NB
authors.lastname: Lopanik
authors.forename: Noah P
authors.initials: NP
authors.lastname: Gardner
authors.forename: Kristina
authors.initials: K
authors.lastname: Håkansson
authors.forename: David H
authors.initials: DH
authors.lastname: Sherman
mesh_terms: D000213:Acyl Carrier Protein / Q000737:chemistry / Q000378:metabolism; D000595:Amino Acid Sequence; D054713:Bryostatins / Q000096:biosynthesis*; D020134:Catalytic Domain; D006904:Hydroxymethylglutaryl-CoA Synthase / Q000737:chemistry / Q000145:classification / Q000378:metabolism*; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013379:Substrate Specificity; D020349:Surface Plasmon Resonance
chemical_list: D000213:Acyl Carrier Protein; D054713:Bryostatins; C046785:bryostatin 1; D006904:Hydroxymethylglutaryl-CoA Synthase