Inhibition of interferon-α-induced signaling by hyperosmolarity and hydrophobic bile acids.
Graf
Dirk
D
Department of Gastroenterology, Hepatology and Infectiology, Heinrich Heine University Düsseldorf, D-40225 Düsseldorf, Germany. DirkGraf@gmx.net
Haselow
Katrin
K
Münks
Ivo
I
Bode
Johannes G
JG
Häussinger
Dieter
D
D001622:Betaine / Q000494:pharmacology; D019204:GTP-Binding Proteins / Q000235:genetics; D005786:Gene Expression Regulation / Q000187:drug effects; D005999:Glycochenodeoxycholic Acid / Q000737:chemistry* / Q000494:pharmacology*; D056945:Hep G2 Cells; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D050835:Interferon Regulatory Factors / Q000378:metabolism; D016898:Interferon-alpha / Q000378:metabolism / Q000494:pharmacology*; D064547:Myxovirus Resistance Proteins; D009994:Osmolar Concentration; D050794:STAT1 Transcription Factor / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects*; D013655:Taurochenodeoxycholic Acid / Q000737:chemistry* / Q000494:pharmacology*
D050835:Interferon Regulatory Factors; D016898:Interferon-alpha; C579071:MX1 protein, human; D064547:Myxovirus Resistance Proteins; D050794:STAT1 Transcription Factor; D001622:Betaine; D013655:Taurochenodeoxycholic Acid; D005999:Glycochenodeoxycholic Acid; D019204:GTP-Binding Proteins