TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells.
Albacker
Lee A
LA
Division of Immunology, Children's Hospital Boston, Boston, MA 02115, USA.
Karisola
Piia
P
Chang
Ya-Jen
YJ
Umetsu
Sarah E
SE
Zhou
Meixia
M
Akbari
Omid
O
Kobayashi
Norimoto
N
Baumgarth
Nicole
N
Freeman
Gordon J
GJ
Umetsu
Dale T
DT
DeKruyff
Rosemarie H
RH
D016475:3T3 Cells; D056704:Adaptive Immunity; D019264:Adoptive Transfer; D000818:Animals; D018984:Epitopes, T-Lymphocyte / Q000008:administration & dosage / Q000276:immunology*; D005260:Female; D018655:Lymphocyte Count; D008565:Membrane Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008822:Mice, Transgenic; D010047:Ovalbumin / Q000008:administration & dosage / Q000276:immunology; D010587:Phagocytosis / Q000276:immunology*; D010718:Phosphatidylserines / Q000096:biosynthesis / Q000378:metabolism*; D051381:Rats; D011917:Rats, Inbred Lew; D011956:Receptors, Cell Surface / Q000096:biosynthesis / Q000502:physiology*; D016176:T-Lymphocyte Subsets / Q000276:immunology* / Q000378:metabolism / Q000637:transplantation
D018984:Epitopes, T-Lymphocyte; D008565:Membrane Proteins; D010718:Phosphatidylserines; D011956:Receptors, Cell Surface; C500399:TIM-4 protein, mouse; C512411:TIMD4 protein, human; C408123:phosphatidylserine receptor; D010047:Ovalbumin