title: Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.
authors.affiliation: Department of Pathology, Loyola University Chicago, Maywood, IL 60153, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Grudzien
authors.forename: Shelly
authors.initials: S
authors.lastname: Lo
authors.forename: Kathy S
authors.initials: KS
authors.lastname: Albain
authors.forename: Patricia
authors.initials: P
authors.lastname: Robinson
authors.forename: Prabha
authors.initials: P
authors.lastname: Rajan
authors.forename: Peter R
authors.initials: PR
authors.lastname: Strack
authors.forename: Todd E
authors.initials: TE
authors.lastname: Golde
authors.forename: Lucio
authors.initials: L
authors.lastname: Miele
authors.forename: Kimberly E
authors.initials: KE
authors.lastname: Foreman
mesh_terms: D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*; D045744:Cell Line, Tumor; D003499:Cyclic S-Oxides / Q000494:pharmacology; D005260:Female; D006801:Humans; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000096:biosynthesis; D051880:Receptors, Notch / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D018874:Spheroids, Cellular; D013830:Thiadiazoles / Q000494:pharmacology
chemical_list: D053829:Amyloid Precursor Protein Secretases; D003499:Cyclic S-Oxides; D018719:Erb-b2 Receptor Tyrosine Kinases; D051880:Receptors, Notch; D013830:Thiadiazoles; C523799:MRK 003