Effect of immunoglobulin G (IgG) interchain disulfide bond cleavage on efficacy of intravenous immunoglobulin for immune thrombocytopenic purpura (ITP).
Machino
Y
Y
Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Ohta
H
H
Suzuki
E
E
Higurashi
S
S
Tezuka
T
T
Nagashima
H
H
Kohroki
J
J
Masuho
Y
Y
D000478:Alkylation; D000818:Animals; D000915:Antibody Affinity / Q000187:drug effects*; D004195:Disease Models, Animal; D018450:Disease Progression; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D007167:Immunotherapy; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D017452:Receptors, IgG / Q000737:chemistry / Q000378:metabolism; D016896:Treatment Outcome
C021306:IgG, sulfonated; D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; D017452:Receptors, IgG