GMI, a Ganoderma immunomodulatory protein, down-regulates tumor necrosis factor α-induced expression of matrix metalloproteinase 9 via NF-κB pathway in human alveolar epithelial A549 cells.
Lin
Ching-Hsiung
CH
Division of Chest Medicine, Changhua Christian Hospital, Changhua, Taiwan, Republic of China.
Hsiao
Yi-Min
YM
Ou
Chu-Chyn
CC
Lin
Yu-Wen
YW
Chiu
Yi-Lin
YL
Lue
Ko-Huang
KH
Chang
Jan-Gowth
JG
Ko
Jiunn-Liang
JL
D045744:Cell Line, Tumor; D015536:Down-Regulation / Q000187:drug effects*; D004847:Epithelial Cells / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D005656:Fungal Proteins / Q000276:immunology / Q000494:pharmacology*; D032902:Ganoderma / Q000737:chemistry / Q000276:immunology*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology / Q000494:pharmacology*; D020780:Matrix Metalloproteinase 9 / Q000235:genetics* / Q000276:immunology; D016328:NF-kappa B / Q000235:genetics / Q000276:immunology*; D011650:Pulmonary Alveoli / Q000166:cytology / Q000187:drug effects / Q000201:enzymology / Q000276:immunology*; D015398:Signal Transduction / Q000187:drug effects; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
D005656:Fungal Proteins; D007155:Immunologic Factors; D016328:NF-kappa B; D014409:Tumor Necrosis Factor-alpha; D020780:Matrix Metalloproteinase 9