Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors.
Zhou
Jin
J
Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Tracy
Timothy S
TS
Remmel
Rory P
RP
D001663:Bilirubin / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004958:Estradiol / Q000031:analogs & derivatives* / Q000378:metabolism; D020719:Glucuronides / Q000378:metabolism*; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism; D057809:HEK293 Cells; D006801:Humans; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D013379:Substrate Specificity; D000099148:UGT1A1 Enzyme
D001663:Bilirubin; D004958:Estradiol; D020719:Glucuronides; D014453:Glucuronosyltransferase; D004364:Pharmaceutical Preparations; D011994:Recombinant Proteins; D000099148:UGT1A1 Enzyme; C025482:estradiol-3-glucuronide