title: Specificity of a prodrug-activating enzyme hVACVase: the leaving group effect.
authors.affiliation: Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109-1065, United States.
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.forename: Arik
authors.initials: A
authors.lastname: Dahan
authors.forename: Zachary F
authors.initials: ZF
authors.lastname: Walls
authors.forename: Longsheng
authors.initials: L
authors.lastname: Lai
authors.forename: Kyung-Dall
authors.initials: KD
authors.lastname: Lee
authors.forename: Gordon L
authors.initials: GL
authors.lastname: Amidon
mesh_terms: D000577:Amides / Q000737:chemistry / Q000378:metabolism*; D055162:Biocatalysis; D002265:Carboxylic Ester Hydrolases / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D011355:Prodrugs / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity
chemical_list: D000577:Amides; D011355:Prodrugs; C093745:BPHL protein, human; D002265:Carboxylic Ester Hydrolases