Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cells through ERK and p38 MAP kinase.
Talukder
Parimal
P
Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1, Nanakuma, Jonan- ku, Fukuoka 814-0180, Japan.
Satho
Tomomitsu
T
Irie
Keiichi
K
Sharmin
Tanjina
T
Hamady
Dieng
D
Nakashima
Yukihiko
Y
Kashige
Nobuhiro
N
Miake
Fumio
F
D023181:Antimicrobial Cationic Peptides / Q000276:immunology / Q000378:metabolism*; D018938:Caco-2 Cells; D004305:Dose-Response Relationship, Drug; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism*; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000187:drug effects* / Q000201:enzymology / Q000276:immunology; D013997:Time Factors; D015032:Zinc / Q000494:pharmacology*; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism*; D054804:Cathelicidins
D023181:Antimicrobial Cationic Peptides; D048049:Extracellular Signal-Regulated MAP Kinases; D048051:p38 Mitogen-Activated Protein Kinases; D015032:Zinc; D054804:Cathelicidins