Cyclosporin A inhibits hepatitis C virus replication and restores interferon-alpha expression in hepatocytes.
Liu
J-P
JP
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.
Ye
L
L
Wang
X
X
Li
J-L
JL
Ho
W-Z
WZ
D002460:Cell Line; D016572:Cyclosporine / Q000494:pharmacology*; D005786:Gene Expression Regulation; D016174:Hepacivirus / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D006526:Hepatitis C / Q000188:drug therapy / Q000517:prevention & control; D022781:Hepatocytes / Q000276:immunology / Q000378:metabolism / Q000821:virology*; D006801:Humans; D007113:Immunity, Innate; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D050856:Interferon Regulatory Factor-1 / Q000235:genetics / Q000378:metabolism; D016898:Interferon-alpha / Q000378:metabolism*; D016031:Liver Transplantation / Q000009:adverse effects; D012367:RNA, Viral / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015854:Up-Regulation; D014764:Viral Proteins / Q000378:metabolism; D014779:Virus Replication / Q000187:drug effects*
D007166:Immunosuppressive Agents; D050856:Interferon Regulatory Factor-1; D016898:Interferon-alpha; D012367:RNA, Viral; D014764:Viral Proteins; D016572:Cyclosporine