Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration.
Peng
Jun
J
Buck Institute for Age Research, Novato, California 94945, USA.
Oo
May Lin
ML
Andersen
Julie K
JK
D000375:Aging / Q000235:genetics* / Q000473:pathology; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D018450:Disease Progression; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D007501:Iron / Q000633:toxicity; D051379:Mice; D008822:Mice, Transgenic; D009154:Mutation / Q000235:genetics*; D009410:Nerve Degeneration / Q000139:chemically induced / Q000235:genetics* / Q000473:pathology; D010269:Paraquat / Q000633:toxicity; D010300:Parkinson Disease / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D051381:Rats; D012307:Risk Factors; D051844:alpha-Synuclein / Q000235:genetics
D051844:alpha-Synuclein; D007501:Iron; D010269:Paraquat