title: NOD2, CD14 and TLR4 mutations do not influence response to adalimumab in patients with Crohn's disease: a preliminary report.
authors.affiliation: Gastroenterology, University Hospital of Santiago de Compostela, Spain. manubarreiro@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Barreiro-de Acosta
authors.forename: S
authors.initials: S
authors.lastname: Ouburg
authors.forename: S A
authors.initials: SA
authors.lastname: Morré
authors.forename: J B A
authors.initials: JB
authors.lastname: Crusius
authors.forename: A
authors.initials: A
authors.lastname: Lorenzo
authors.forename: J
authors.initials: J
authors.lastname: Potel
authors.forename: A
authors.initials: A
authors.lastname: Salvador-Peña
authors.forename: J E
authors.initials: JE
authors.lastname: Domínguez-Muñoz
mesh_terms: D000068879:Adalimumab; D000328:Adult; D017668:Age of Onset; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D003424:Crohn Disease / Q000188:drug therapy* / Q000235:genetics*; D016207:Cytokines / Q000378:metabolism; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D018950:Lipopolysaccharide Receptors / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D053473:Nod2 Signaling Adaptor Protein / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D020133:Reverse Transcriptase Polymerase Chain Reaction; D051197:Toll-Like Receptor 4 / Q000235:genetics*
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D016207:Cytokines; D005819:Genetic Markers; D018950:Lipopolysaccharide Receptors; C429018:NOD2 protein, human; D053473:Nod2 Signaling Adaptor Protein; D051197:Toll-Like Receptor 4; D000068879:Adalimumab