The predictive validity of the rat self-administration model for abuse liability.
O'Connor
Eoin C
EC
Global Safety Pharmacology, Drug Safety Research and Development, Pfizer Global Research and Development, Sandwich, CT13 9NJ, UK.
Chapman
Kathryn
K
Butler
Paul
P
Mead
Andy N
AN
D000818:Animals; D004195:Disease Models, Animal; D004334:Drug Administration Schedule; D005508:Food Deprivation; D006801:Humans; D011237:Predictive Value of Tests; D051381:Rats; D015203:Reproducibility of Results; D012107:Research Design; D012646:Self Administration; D019966:Substance-Related Disorders / Q000503:physiopathology* / Q000523:psychology*