Pharmacokinetics of deferiprone in patients with β-thalassaemia: impact of splenectomy and iron status.
Limenta
Lie Michael George
LM
Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Jirasomprasert
Totsapol
T
Jittangprasert
Piyada
P
Wilairat
Prapin
P
Yamanont
Praveena
P
Chantharaksri
Udom
U
Fucharoen
Suthat
S
Morales
Noppawan Phumala
NP
D000284:Administration, Oral; D000328:Adult; D019540:Area Under Curve; D000077543:Deferiprone; D005260:Female; D005293:Ferritins / Q000378:metabolism; D006446:Hemoglobin E / Q000032:analysis; D006801:Humans; D007501:Iron / Q000493:pharmacokinetics*; D007502:Iron Chelating Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use; D019190:Iron Overload / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D008297:Male; D011728:Pyridones / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use; D013156:Splenectomy; D014168:Transferrin / Q000378:metabolism; D065227:Transfusion Reaction; D017086:beta-Thalassemia / Q000097:blood* / Q000628:therapy
D007502:Iron Chelating Agents; D011728:Pyridones; D014168:Transferrin; D000077543:Deferiprone; D005293:Ferritins; D006446:Hemoglobin E; D007501:Iron