Small molecule inhibitors of NF-kB and JAK/STAT signal transduction pathways as promising anti-inflammatory therapeutics.
Ivanenkov
Y A
YA
ChemDiv, Inc. 6605 Nancy Ridge Drive, San Diego, CA 92121, USA. yai@chemdiv.com
Balakin
K V
KV
Lavrovsky
Y
Y
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000473:pathology; D053612:Janus Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000378:metabolism*; D050791:STAT Transcription Factors / Q000037:antagonists & inhibitors / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D016328:NF-kappa B; D050791:STAT Transcription Factors; D053612:Janus Kinases