Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix.
Leal
Cecília
C
Physics, Materials, and Molecular, Cellular & Developmental Biology Departments, University of California, Santa Barbara, California 93106, United States. cecilial@mrl.ucsb.edu
Bouxsein
Nathan F
NF
Ewert
Kai K
KK
Safinya
Cyrus R
CR
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D008081:Liposomes / Q000737:chemistry* / Q000378:metabolism* / Q000633:toxicity; D051379:Mice; D008853:Microscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D034622:RNA Interference; D034741:RNA, Small Interfering / Q000235:genetics* / Q000378:metabolism*; D053838:Scattering, Small Angle; D014961:X-Ray Diffraction
D008081:Liposomes; D034741:RNA, Small Interfering