Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.
El-Awady
El-Sayed E
el-SE
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt. sayedawady@yahoo.com
Moustafa
Yasser M
YM
Abo-Elmatty
Dina M
DM
Radwan
Asmaa
A
D000108:Acetylcarnitine / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D015415:Biomarkers / Q000378:metabolism; D002316:Cardiotonic Agents / Q000494:pharmacology*; D054715:Cardiotoxins / Q000009:adverse effects*; D002467:Cell Nucleus / Q000187:drug effects / Q000235:genetics; D002945:Cisplatin / Q000009:adverse effects*; D053938:DNA Fragmentation / Q000187:drug effects; D004272:DNA, Mitochondrial / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D051381:Rats; D012838:Silymarin / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000378:metabolism; D008063:Thioctic Acid / Q000494:pharmacology
D000975:Antioxidants; D015415:Biomarkers; D002316:Cardiotonic Agents; D054715:Cardiotoxins; D004272:DNA, Mitochondrial; D012838:Silymarin; D000108:Acetylcarnitine; D008063:Thioctic Acid; D013482:Superoxide Dismutase; D005978:Glutathione; D002945:Cisplatin