The α-MSH analogue AP214 attenuates rise in pulmonary pressure and fall in ejection fraction in lipopolysaccharide-induced systemic inflammatory response syndrome in pigs.
Kristensen
Jens
J
Department of Clinical Physiology ⁄The Institute of Clinical Medicine, Aarhus University Hospital, Skejby, Aarhus, Denmark. jenskristensen@dadlnet.dk
Jonassen
Thomas E N
TE
Rehling
Michael
M
Tønnesen
Else
E
Sloth
Erik
E
Nielsen
Søren
S
Frøkiaer
Jørgen
J
D000818:Animals; D004452:Echocardiography; D004731:Endotoxins / Q000494:pharmacology; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000187:drug effects / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D008070:Lipopolysaccharides; D008168:Lung / Q000098:blood supply / Q000187:drug effects / Q000503:physiopathology; D013552:Swine; D018746:Systemic Inflammatory Response Syndrome / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D014655:Vascular Resistance / Q000187:drug effects; D016277:Ventricular Function, Left / Q000187:drug effects; D000521:alpha-MSH / Q000031:analogs & derivatives* / Q000494:pharmacology
C530134:AP 214; D004731:Endotoxins; D008070:Lipopolysaccharides; D000521:alpha-MSH