title: Antiobesity effect of MK-5046, a novel bombesin receptor subtype-3 agonist.
authors.affiliation: Department of Metabolic Disorders, Merck Research Laboratories, Rahway, New Jersey 07065-0900, USA. xiaoming.x.guan@gsk.com
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Guan
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Metzger
authors.forename: Liming
authors.initials: L
authors.lastname: Yang
authors.forename: Kate A
authors.initials: KA
authors.lastname: Raustad
authors.forename: Sheng-Ping
authors.initials: SP
authors.lastname: Wang
authors.forename: Stephanie K
authors.initials: SK
authors.lastname: Spann
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Kosinski
authors.forename: Hong
authors.initials: H
authors.lastname: Yu
authors.forename: Lauren P
authors.initials: LP
authors.lastname: Shearman
authors.forename: Terry D
authors.initials: TD
authors.lastname: Faidley
authors.forename: Oksana
authors.initials: O
authors.lastname: Palyha
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Kan
authors.forename: Theresa M
authors.initials: TM
authors.lastname: Kelly
authors.forename: Iyassu
authors.initials: I
authors.lastname: Sebhat
authors.forename: Linus S
authors.initials: LS
authors.lastname: Lin
authors.forename: Jasminka
authors.initials: J
authors.lastname: Dragovic
authors.forename: Kathy A
authors.initials: KA
authors.lastname: Lyons
authors.forename: Stephanie
authors.initials: S
authors.lastname: Craw
authors.forename: Ravi P
authors.initials: RP
authors.lastname: Nargund
authors.forename: Donald J
authors.initials: DJ
authors.lastname: Marsh
authors.forename: Alison M
authors.initials: AM
authors.lastname: Strack
authors.forename: Marc L
authors.initials: ML
authors.lastname: Reitman
mesh_terms: D000818:Animals; D019440:Anti-Obesity Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects; D004734:Energy Metabolism / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011720:Pyrazoles / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D018004:Receptors, Bombesin / Q000819:agonists* / Q000032:analysis
chemical_list: C556243:1,1,1-trifluoro-2-(4-(1H-pyrazol-1-yl)phenyl)-3-(4-((1-(trifluoromethyl)cyclopropyl)methyl)-1H-imidazol-2-yl)propan-2-ol; D019440:Anti-Obesity Agents; D007093:Imidazoles; D011720:Pyrazoles; D018004:Receptors, Bombesin; C107120:bombesin receptor subtype 3