A novel antiangiogenic peptide derived from hepatocyte growth factor inhibits neovascularization in vitro and in vivo.
Xu
Yi
Y
Department of Ophthalmology, Shanghai First People’s Hospital, Shanghai JiaoTong University, Shanghai, China.
Zhao
Hui
H
Zheng
Ying
Y
Gu
Qing
Q
Ma
Jianxing
J
Xu
Xun
X
D020533:Angiogenesis Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002645:Chickens; D049033:Chorioallantoic Membrane / Q000098:blood supply / Q000187:drug effects; D042783:Endothelial Cells / Q000187:drug effects / Q000473:pathology; D017228:Hepatocyte Growth Factor / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008251:Macaca; D051379:Mice; D008810:Mice, Inbred C57BL; D010446:Peptide Fragments / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use*; D010455:Peptides / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D055550:Protein Stability / Q000187:drug effects; D015861:Retinal Neovascularization / Q000188:drug therapy* / Q000473:pathology; D042461:Vascular Endothelial Growth Factor A / Q000494:pharmacology
D020533:Angiogenesis Inhibitors; C581855:H-RN peptide; D010446:Peptide Fragments; D010455:Peptides; D042461:Vascular Endothelial Growth Factor A; D017228:Hepatocyte Growth Factor