title: PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.
authors.affiliation: Department of Medicine/Dermatology, University of Washington, Seattle, WA 98195-6524, USA.
authors.forename: Maryam G
authors.initials: MG
authors.lastname: Rohani
authors.forename: Dennis H
authors.initials: DH
authors.lastname: DiJulio
authors.forename: Jonathan Y
authors.initials: JY
authors.lastname: An
authors.forename: Beth M
authors.initials: BM
authors.lastname: Hacker
authors.forename: Beverly A
authors.initials: BA
authors.lastname: Dale
authors.forename: Whasun O
authors.initials: WO
authors.lastname: Chung
mesh_terms: D002478:Cells, Cultured; D054418:Chemokine CCL20 / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D054365:Chemokine CXCL5 / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D019743:Chemokines, CXC / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D015536:Down-Regulation; D006801:Humans; D007113:Immunity, Innate; D015603:Keratinocytes / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D048052:Mitogen-Activated Protein Kinase 3 / Q000378:metabolism; D009055:Mouth / Q000473:pathology; D010518:Periodontitis / Q000235:genetics / Q000276:immunology* / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D044463:Receptor, PAR-1 / Q000276:immunology / Q000378:metabolism*; D044464:Receptor, PAR-2 / Q000276:immunology / Q000378:metabolism*; D015398:Signal Transduction / Q000276:immunology; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism
chemical_list: C499707:CXCL3 protein, human; D054418:Chemokine CCL20; D054365:Chemokine CXCL5; D019743:Chemokines, CXC; D044463:Receptor, PAR-1; D044464:Receptor, PAR-2; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt; D048052:Mitogen-Activated Protein Kinase 3; D048051:p38 Mitogen-Activated Protein Kinases