Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation.
Bhogal
Ricky Harminder
RH
Centre for Liver Research, Institute for Biomedical Research, Medical School, University of Birmingham, Birmingham, United Kingdom. balsin@hotmail.com
Curbishley
Stuart M
SM
Weston
Christopher J
CJ
Adams
David H
DH
Afford
Simon C
SC
D000111:Acetylcysteine / Q000494:pharmacology; D017304:Annexin A5 / Q000032:analysis; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D005260:Female; D005434:Flow Cytometry; D022781:Hepatocytes / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D000860:Hypoxia / Q000378:metabolism* / Q000473:pathology; D007249:Inflammation / Q000188:drug therapy; D007728:Kupffer Cells / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000378:metabolism* / Q000473:pathology; D008107:Liver Diseases / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D019255:NADPH Oxidases / Q000037:antagonists & inhibitors / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015427:Reperfusion Injury / Q000378:metabolism / Q000473:pathology; D055815:Young Adult
D017304:Annexin A5; D000975:Antioxidants; D017382:Reactive Oxygen Species; D019255:NADPH Oxidases; D000111:Acetylcysteine