title: Polyphenols-rich Vernonia amygdalina shows anti-diabetic effects in streptozotocin-induced diabetic rats.
authors.affiliation: Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
authors.forename: Khang Wei
authors.initials: KW
authors.lastname: Ong
authors.forename: Annie
authors.initials: A
authors.lastname: Hsu
authors.forename: LiXia
authors.initials: L
authors.lastname: Song
authors.forename: DeJian
authors.initials: D
authors.lastname: Huang
authors.forename: Benny Kwong Huat
authors.initials: BK
authors.lastname: Tan
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D004305:Dose-Response Relationship, Drug; D020834:Ethnopharmacology; D005419:Flavonoids / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D051272:Glucose Transporter Type 1 / Q000378:metabolism; D051275:Glucose Transporter Type 4 / Q000378:metabolism; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D007328:Insulin / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008687:Metformin / Q000494:pharmacology; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D010636:Phenols / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D059808:Polyphenols; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000097:blood; D035741:Vernonia / Q000737:chemistry
chemical_list: D000975:Antioxidants; D001786:Blood Glucose; D005419:Flavonoids; D051272:Glucose Transporter Type 1; D051275:Glucose Transporter Type 4; D007004:Hypoglycemic Agents; D007328:Insulin; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols; C495679:Slc2a1 protein, rat; C495694:Slc2a4 protein, rat; D014280:Triglycerides; D008687:Metformin; D002784:Cholesterol; D005952:Glucose-6-Phosphatase; D005978:Glutathione