β-Lapachone-induced reactive oxygen species (ROS) generation mediates autophagic cell death in glioma U87 MG cells.
Park
Eun Jung
EJ
Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, South Korea.
Choi
Kyeong Sook
KS
Kwon
Taeg Kyu
TK
D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology; D001343:Autophagy / Q000187:drug effects*; D015153:Blotting, Western; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005434:Flow Cytometry; D005910:Glioma / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D018942:Macrolides / Q000494:pharmacology; D008856:Microscopy, Fluorescence; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000037:antagonists & inhibitors / Q000378:metabolism; D009285:Naphthoquinones / Q000494:pharmacology*; D034741:RNA, Small Interfering / Q000008:administration & dosage / Q000235:genetics; D017382:Reactive Oxygen Species / Q000378:metabolism*
D004791:Enzyme Inhibitors; D018942:Macrolides; D009285:Naphthoquinones; D034741:RNA, Small Interfering; D017382:Reactive Oxygen Species; C025946:3-methyladenine; C014638:beta-lapachone; C040929:bafilomycin A1; D016660:NAD(P)H Dehydrogenase (Quinone); C447479:NQO1 protein, human; D000225:Adenine