Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Vondálová Blanárová
Olga
O
Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Czech Republic.
Jelínková
Iva
I
Szöor
Arpád
A
Skender
Belma
B
Soucek
Karel
K
Horváth
Viktor
V
Vaculová
Alena
A
Andera
Ladislav
L
Sova
Petr
P
Szöllosi
János
J
Hofmanová
Jirina
J
Vereb
György
G
Kozubík
Alois
A
D000547:Amantadine / Q000031:analogs & derivatives* / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects* / Q000502:physiology; D015153:Blotting, Western; D045744:Cell Line, Tumor; D002469:Cell Separation; D002945:Cisplatin / Q000494:pharmacology*; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D006801:Humans; D018613:Microscopy, Confocal; D009369:Neoplasms / Q000378:metabolism*; D009944:Organoplatinum Compounds / Q000494:pharmacology*; D021381:Protein Transport / Q000187:drug effects; D034622:RNA Interference; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000378:metabolism*
D009944:Organoplatinum Compounds; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand; D053221:TNF-Related Apoptosis-Inducing Ligand; C482801:bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV); D000547:Amantadine; D002945:Cisplatin