Pharmacological inhibition of tumor necrosis factor may reduce pain behavior changes induced by experimental disc puncture in the rat: an experimental study in rats.
Nakamae
Toshio
T
Department of Medical Chemistry and Cell Biology, Musculoskeletal Research, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ochi
Mitsuo
M
Olmarker
Kjell
K
D000704:Analysis of Variance; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000276:immunology / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D004318:Doxycycline / Q000008:administration & dosage / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005260:Female; D000069285:Infliximab; D007274:Injections, Intraperitoneal; D007403:Intervertebral Disc / Q000187:drug effects* / Q000503:physiopathology / Q000601:surgery; D007796:Laminectomy / Q000009:adverse effects; D017116:Low Back Pain / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D010147:Pain Measurement / Q000379:methods; D051381:Rats; D017207:Rats, Sprague-Dawley; D013129:Spinal Puncture / Q000009:adverse effects; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis* / Q000276:immunology
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab; D004318:Doxycycline