title: Orexin receptors: pharmacology and therapeutic opportunities.
authors.affiliation: Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. tscammel@bidmc.harvard.edu
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Scammell
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Winrow
mesh_terms: D000818:Animals; D015195:Drug Design; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D007031:Hypothalamus / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled / Q000037:antagonists & inhibitors* / Q000378:metabolism; D018013:Receptors, Neuropeptide / Q000037:antagonists & inhibitors* / Q000378:metabolism; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: C000596229:HCRT protein, human; D006993:Hypnotics and Sedatives; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled; D018013:Receptors, Neuropeptide