Reversible inhibition of three important human liver cytochrome p450 enzymes by tiliroside.
Sun
Dong-Xue
DX
School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, China.
Lu
Jin-Cai
JC
Fang
Zhong-Ze
ZZ
Zhang
Yan-Yan
YY
Cao
Yun-Feng
YF
Mao
Yu-Xi
YX
Zhu
Liang-Liang
LL
Yin
Jun
J
Yang
Ling
L
D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors*; D065727:Cytochrome P-450 CYP2C8; D065729:Cytochrome P-450 CYP2C9; D051544:Cytochrome P-450 CYP3A; D065692:Cytochrome P-450 CYP3A Inhibitors; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects
D065692:Cytochrome P-450 CYP3A Inhibitors; D005419:Flavonoids; C052083:tiliroside; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; C450259:CYP2C8 protein, human; D065727:Cytochrome P-450 CYP2C8; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human