The discovery of new spirocyclic muscarinic M3 antagonists.
Stocks
Michael J
MJ
Department of Chemistry, AstraZeneca R&D Charnwood, Loughborough, Leicestershire, UK. mike.stocks@astrazeneca.com
Alcaraz
Lilian
L
Bailey
Andrew
A
Bowers
Keith
K
Donald
David
D
Edwards
Helen
H
Hunt
Fraser
F
Kindon
Nicholas
N
Pairaudeau
Garry
G
Theaker
Jill
J
Warner
Daniel J
DJ
D000818:Animals; D004353:Drug Evaluation, Preclinical; D022781:Hepatocytes / Q000378:metabolism; D006801:Humans; D008861:Microsomes / Q000378:metabolism; D051381:Rats; D043587:Receptor, Muscarinic M3 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013141:Spiro Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
D043587:Receptor, Muscarinic M3; D013141:Spiro Compounds