title: The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes.
authors.affiliation: Department of Medicine III, University Hospital Aachen, Aachen, Germany.
authors.forename: Karlin Raja
authors.initials: KR
authors.lastname: Karlmark
authors.forename: Henning W
authors.initials: HW
authors.lastname: Zimmermann
authors.forename: Christoph
authors.initials: C
authors.lastname: Roderburg
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Gassler
authors.forename: Hermann E
authors.initials: HE
authors.lastname: Wasmuth
authors.forename: Tom
authors.initials: T
authors.lastname: Luedde
authors.forename: Christian
authors.initials: C
authors.lastname: Trautwein
authors.forename: Frank
authors.initials: F
authors.lastname: Tacke
mesh_terms: D000199:Actins / Q000235:genetics; D000410:Alanine Transaminase / Q000235:genetics; D000818:Animals; D016026:Bone Marrow Transplantation; D000073883:CX3C Chemokine Receptor 1; D002454:Cell Differentiation / Q000187:drug effects*; D003433:Crosses, Genetic; D005434:Flow Cytometry; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000235:genetics; D006801:Humans; D007962:Leukocytes / Q000166:cytology* / Q000502:physiology; D008099:Liver / Q000166:cytology* / Q000187:drug effects; D008103:Liver Cirrhosis / Q000517:prevention & control*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009000:Monocytes / Q000166:cytology* / Q000187:drug effects; D016133:Polymerase Chain Reaction; D019707:Receptors, Chemokine / Q000172:deficiency / Q000627:therapeutic use*
chemical_list: D000199:Actins; D000073883:CX3C Chemokine Receptor 1; C095235:CX3CR1 protein, human; C471885:Cx3cr1 protein, mouse; D019707:Receptors, Chemokine; C544013:alpha-smooth muscle actin, mouse; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D000410:Alanine Transaminase