Zinc-suppressed inflammatory cytokines by induction of A20-mediated inhibition of nuclear factor-κB.
Prasad
Ananda S
AS
Department of Internal Medicine, Division of Hematology/Oncology, Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, Michigan, USA. prasada@karmanos.org
Bao
Bin
B
Beck
Frances W J
FW
Sarkar
Fazlul H
FH
D002460:Cell Line; D016207:Cytokines / Q000378:metabolism*; D004268:DNA-Binding Proteins; D015536:Down-Regulation; D042783:Endothelial Cells / Q000378:metabolism*; D006801:Humans; D020672:I-kappa B Proteins / Q000037:antagonists & inhibitors; D018836:Inflammation Mediators / Q000378:metabolism*; D053583:Interleukin-1beta / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D016328:NF-kappa B / Q000037:antagonists & inhibitors*; D009687:Nuclear Proteins / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology; D015398:Signal Transduction; D047990:TNF Receptor-Associated Factor 1 / Q000378:metabolism; D000072598:Tumor Necrosis Factor alpha-Induced Protein 3; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D014471:Umbilical Veins / Q000166:cytology; D015032:Zinc / Q000378:metabolism*
D016207:Cytokines; D004268:DNA-Binding Proteins; D020672:I-kappa B Proteins; D018836:Inflammation Mediators; D053583:Interleukin-1beta; D047908:Intracellular Signaling Peptides and Proteins; D016328:NF-kappa B; D009687:Nuclear Proteins; D047990:TNF Receptor-Associated Factor 1; D014409:Tumor Necrosis Factor-alpha; C076529:TNFAIP3 protein, human; D000072598:Tumor Necrosis Factor alpha-Induced Protein 3; D015032:Zinc