Iron loading-induced aggregation and reduction of iron incorporation in heteropolymeric ferritin containing a mutant light chain that causes neurodegeneration.
Muhoberac
Barry B
BB
Department of Chemistry and Chemical Biology, Indiana University-Purdue University, Indianapolis, IN 46202, USA. bmuhober@iupui.edu
Baraibar
Martin A
MA
Vidal
Ruben
R
D001052:Apoferritins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011232:Chemical Precipitation; D005293:Ferritins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D020271:Heredodegenerative Disorders, Nervous System / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism*; D009154:Mutation; D009410:Nerve Degeneration / Q000235:genetics / Q000378:metabolism; D058105:Polymerization; D012995:Solubility
D005293:Ferritins; D001052:Apoferritins; D007501:Iron