title: A novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cells.
authors.affiliation: School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, PR China.
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Shumei
authors.initials: S
authors.lastname: Zhai
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Liu
authors.forename: Liwen
authors.initials: L
authors.lastname: Li
authors.forename: Shirley
authors.initials: S
authors.lastname: Wu
authors.forename: Q Ping
authors.initials: QP
authors.lastname: Dou
authors.forename: Bing
authors.initials: B
authors.lastname: Yan
mesh_terms: D000444:Aldehyde Dehydrogenase / Q000037:antagonists & inhibitors*; D017209:Apoptosis / Q000187:drug effects*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D045744:Cell Line, Tumor; D003300:Copper / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005260:Female; D006801:Humans; D061988:Proteasome Inhibitors; D011759:Pyrrolidines / Q000494:pharmacology; D013859:Thiocarbamates / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D061988:Proteasome Inhibitors; D011759:Pyrrolidines; D013859:Thiocarbamates; C020972:pyrrolidine dithiocarbamic acid; D003300:Copper; D000444:Aldehyde Dehydrogenase