Suppression of transforming growth factor-β effects in rabbit subconjunctival fibroblasts by activin receptor-like kinase 5 inhibitor.
Sapitro
Jennifer
J
Department of Ophthalmology, Summa Health System, Akron, OH, USA.
Dunmire
Jeffrey J
JJ
Scott
Sarah E
SE
Sutariya
Vijay
V
Geldenhuys
Werner J
WJ
Hewit
Michael
M
Yue
Beatrice Y J T
BY
Nakamura
Hiroshi
H
D000199:Actins / Q000378:metabolism; D000818:Animals; D052117:Benzodioxoles / Q000494:pharmacology*; D001665:Binding Sites; D001681:Biological Assay; D015153:Blotting, Western; D002452:Cell Count; D003228:Conjunctiva / Q000473:pathology*; D055513:Connective Tissue Growth Factor / Q000378:metabolism; D005347:Fibroblasts / Q000187:drug effects* / Q000201:enzymology* / Q000473:pathology; D018463:Filtering Surgery; D005455:Fluorescent Antibody Technique; D005901:Glaucoma / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D007093:Imidazoles / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects; D008958:Models, Molecular; D010766:Phosphorylation / Q000187:drug effects; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011725:Pyridines / Q000494:pharmacology*; D011817:Rabbits; D000077293:Receptor, Transforming Growth Factor-beta Type I; D018125:Receptors, Transforming Growth Factor beta / Q000037:antagonists & inhibitors* / Q000378:metabolism; D051899:Smad2 Protein / Q000378:metabolism; D053781:Transforming Growth Factor beta2 / Q000494:pharmacology*
C519132:2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride; D000199:Actins; D052117:Benzodioxoles; D007093:Imidazoles; D011725:Pyridines; D018125:Receptors, Transforming Growth Factor beta; D051899:Smad2 Protein; D053781:Transforming Growth Factor beta2; D055513:Connective Tissue Growth Factor; D017346:Protein Serine-Threonine Kinases; D000077293:Receptor, Transforming Growth Factor-beta Type I