title: Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa.
authors.affiliation: Department of Chemistry, Université de Montréal, Montréal, QC, Canada. stephen.hanessian@umontreal.ca
authors.forename: Stephen
authors.initials: S
authors.lastname: Hanessian
authors.forename: Andreas
authors.initials: A
authors.lastname: Larsson
authors.forename: Tomas
authors.initials: T
authors.lastname: Fex
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Knecht
authors.forename: Niklas
authors.initials: N
authors.lastname: Blomberg
mesh_terms: D000925:Anticoagulants / Q000138:chemical synthesis* / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects; D015195:Drug Design; D015945:Factor XIa / Q000037:antagonists & inhibitors*; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology*; D015842:Serine Proteinase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000925:Anticoagulants; D007211:Indoles; D015842:Serine Proteinase Inhibitors; D015945:Factor XIa