Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism.
Yang
Guang
G
Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China.
Meng
Ya
Y
Li
Wenxia
W
Yong
Yue
Y
Fan
Zhiqin
Z
Ding
Hanqing
H
Wei
Youzhen
Y
Luo
Jia
J
Ke
Zun-Ji
ZJ
D000818:Animals; D016923:Cell Death / Q000502:physiology; D018932:Chemokine CCL2 / Q000235:genetics / Q000378:metabolism*; D018925:Chemokines / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D017628:Microglia / Q000276:immunology / Q000502:physiology*; D009410:Nerve Degeneration / Q000378:metabolism* / Q000473:pathology; D009474:Neurons / Q000378:metabolism* / Q000473:pathology; D010084:Oxidation-Reduction; D020656:Posterior Thalamic Nuclei / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D017382:Reactive Oxygen Species / Q000378:metabolism; D013832:Thiamine Deficiency / Q000276:immunology / Q000378:metabolism*
C491768:Ccl2 protein, mouse; D018932:Chemokine CCL2; D018925:Chemokines; D017382:Reactive Oxygen Species