title: Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells.
authors.affiliation: Department of Medical Oncology, Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Wu
authors.forename: Shu-Kui
authors.initials: SK
authors.lastname: Qin
authors.forename: Feng-Meng
authors.initials: FM
authors.lastname: Teng
authors.forename: Chang-Jie
authors.initials: CJ
authors.lastname: Chen
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
mesh_terms: D016203:CDC2 Protein Kinase / Q000096:biosynthesis / Q000235:genetics; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D018929:Cell Culture Techniques; D002453:Cell Cycle / Q000187:drug effects; D048708:Cell Growth Processes / Q000187:drug effects; D045744:Cell Line, Tumor; D019926:Cyclin B / Q000096:biosynthesis / Q000235:genetics; D051358:Cyclin-Dependent Kinase 4 / Q000096:biosynthesis / Q000235:genetics; D050759:Cyclin-Dependent Kinase Inhibitor p21 / Q000096:biosynthesis / Q000235:genetics; D050760:Cyclin-Dependent Kinase Inhibitor p27 / Q000096:biosynthesis / Q000235:genetics; D003503:Cyclobutanes / Q000494:pharmacology*; D015536:Down-Regulation / Q000187:drug effects; D050684:E2F Transcription Factors / Q000096:biosynthesis / Q000235:genetics; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D009944:Organoplatinum Compounds / Q000494:pharmacology*; D016160:Retinoblastoma Protein / Q000096:biosynthesis / Q000235:genetics; D016159:Tumor Suppressor Protein p53 / Q000096:biosynthesis / Q000235:genetics; D015854:Up-Regulation / Q000187:drug effects; D020687:cdc25 Phosphatases / Q000096:biosynthesis / Q000235:genetics
chemical_list: C493956:CDKN1A protein, human; D019926:Cyclin B; D050759:Cyclin-Dependent Kinase Inhibitor p21; D003503:Cyclobutanes; D050684:E2F Transcription Factors; D009944:Organoplatinum Compounds; D016160:Retinoblastoma Protein; C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D050760:Cyclin-Dependent Kinase Inhibitor p27; D016203:CDC2 Protein Kinase; C495900:CDK4 protein, human; D051358:Cyclin-Dependent Kinase 4; C517009:CDC25C protein, human; D020687:cdc25 Phosphatases; C066228:lobaplatin