The evaluation of novel natural products as inhibitors of human glutathione transferase P1-1.
Mukanganyama
Stanley
S
Department of Biochemistry, University of Zimbabwe, P.O. Box MP167, Mt. Pleasant, Harare, Zimbabwe. smukanganyama@yahoo.co.uk
Bezabih
Merhatibeb
M
Robert
Metuno
M
Ngadjui
Boneventure T
BT
Kapche
Gilbert F W
GF
Ngandeu
Francois
F
Abegaz
Berhanu
B
D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D051549:Glutathione S-Transferase pi / Q000037:antagonists & inhibitors* / Q000302:isolation & purification / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000302:isolation & purification / Q000378:metabolism; D007700:Kinetics; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D001688:Biological Products; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D010936:Plant Extracts; D011994:Recombinant Proteins; C496556:GSTP1 protein, human; D051549:Glutathione S-Transferase pi