title: A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults.
authors.affiliation: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 40 Convent Drive, Bethesda, MD 20892-3017, United States. Ledgerwood@mail.nih.gov
authors.forename: J E
authors.initials: JE
authors.lastname: Ledgerwood
authors.forename: P
authors.initials: P
authors.lastname: Costner
authors.forename: N
authors.initials: N
authors.lastname: Desai
authors.forename: L
authors.initials: L
authors.lastname: Holman
authors.forename: M E
authors.initials: ME
authors.lastname: Enama
authors.forename: G
authors.initials: G
authors.lastname: Yamshchikov
authors.forename: S
authors.initials: S
authors.lastname: Mulangu
authors.forename: Z
authors.initials: Z
authors.lastname: Hu
authors.forename: C A
authors.initials: CA
authors.lastname: Andrews
authors.forename: R A
authors.initials: RA
authors.lastname: Sheets
authors.forename: R A
authors.initials: RA
authors.lastname: Koup
authors.forename: M
authors.initials: M
authors.lastname: Roederer
authors.forename: R
authors.initials: R
authors.lastname: Bailer
authors.forename: J R
authors.initials: JR
authors.lastname: Mascola
authors.forename: M G
authors.initials: MG
authors.lastname: Pau
authors.forename: N J
authors.initials: NJ
authors.lastname: Sullivan
authors.forename: J
authors.initials: J
authors.lastname: Goudsmit
authors.forename: G J
authors.initials: GJ
authors.lastname: Nabel
authors.forename: B S
authors.initials: BS
authors.lastname: Graham
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000818:Animals; D057134:Antibodies, Neutralizing / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D016207:Cytokines / Q000276:immunology; D004311:Double-Blind Method; D046129:Ebola Vaccines / Q000009:adverse effects / Q000235:genetics / Q000276:immunology*; D029043:Ebolavirus / Q000235:genetics / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005822:Genetic Vectors; D019142:Hemorrhagic Fever, Ebola / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D010919:Placebos / Q000008:administration & dosage; D013601:T-Lymphocytes / Q000276:immunology; D014613:Vaccines, Attenuated / Q000009:adverse effects / Q000235:genetics / Q000276:immunology; D014759:Viral Envelope Proteins / Q000235:genetics / Q000276:immunology*; D055815:Young Adult
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral; D016207:Cytokines; D046129:Ebola Vaccines; D010919:Placebos; D014613:Vaccines, Attenuated; D014759:Viral Envelope Proteins; C113189:envelope glycoprotein, Ebola virus