[Thromboaspiration in primary angioplasty for ST elevation myocardial infarction].
Primary angioplasty is the gold standard for myocardial reperfusion in patients with acute myocardial infarction with ST elevation (STEMI). Fast normalization of infarct-related coronary artery flow and no reflow prevention are correlated with clinical outcomes. Over the last years, many antithrombotic regimens have been evaluated in this setting. The use of a combined pharmacological and mechanical strategy with abciximab, and thromboaspiration of atherothrombotic debris is associated with coronary flow improvement, improvement of myocardial perfusion, and, in fine a better clinical outcome. In this respect, the current guidelines recommend a systematic manuel catheter thromboaspiration of the culprit lesion in STEMI with a class IIa, level of evidence A indication.
Hôpital Guillaume et René Laennec, centre hémodynamique, institut du thorax, Nantes, France. atirouvanziam@chu-nantes.fr
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Tirouvanziam
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Varenne
D015906:Angioplasty, Balloon, Coronary; D003131:Combined Modality Therapy; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D013396:Suction; D013927:Thrombosis / Q000150:complications* / Q000628:therapy*