Lucky number seven: RNase 7 can prevent Staphylococcus aureus skin colonization.
Staphylococcus aureus colonization is a major risk factor for infection. In this issue, Simanski et al. demonstrate that the antimicrobial peptide RNase 7 is essential for preventing S. aureus colonization in human skin. These findings suggest that therapeutic interventions aimed at targeting RNase 7 production in the skin may be a novel strategy to protect against S. aureus infections.
Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
John S
JS
Cho
Caiyun
C
Xuan
Lloyd S
LS
Miller
D004817:Epidermis / Q000276:immunology / Q000382:microbiology; D006801:Humans; D012260:Ribonucleases / Q000276:immunology*; D012307:Risk Factors; D013207:Staphylococcal Skin Infections / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control*; D013211:Staphylococcus aureus / Q000276:immunology*
D012260:Ribonucleases; C470000:Ribonuclease 7