[Study on association rule mining in multi-component Chinese medicine research and development for treatment of lung cancer].
Association rule mining was used to filter high-frequency combinations of chemistry components which were from clinical prescriptions in order to find a new available method for multi-component Chinese medicine research and development. First, 1 120 TCM clinic papers about curing lung cancer were selected from clinic literature database. Second, chemical components were obtained from prescription described in TCM clinic papers through Chinese medicine pharmacological test database. Third, association rule mining was used to find out high-frequency combinations of chemical components. Finally, some interesting conclusions were obtained from association rule mining results through chemical component's pharmacological effects. Association rule mining of Chinese medicine chemical components provided a new method for multi-component Chinese medicine research and development.
Institute of Information on Traditional Chinese Medicine, Academy of Chinese Medicine Science, Beijing 100700, China.
Lei
L
Lei
Meng
M
Cui
Zhongkai
Z
Mi
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008516:Medicine, Chinese Traditional / Q000379:methods* / Q000592:standards
D004365:Drugs, Chinese Herbal