Epidemiological investigation of an acute case of Chagas disease in an area of active transmission in Peruvian Amazon region.
The study objective was to investigate an acute case of Chagas disease in the San Pedro de Shishita community, Pebas District, in the Peruvian Amazon basin, a non-endemic area. Both parents of the index case (acute case) were thoroughly interviewed, a seroepidemiological survey was carried out in the community, parasitological exams were carried out only in relatives of the index case, and triatomine bugs were searched for inside houses, peridomiciliary, and in wild environments. Seroprevalence for IgG anti-T. cruzi antibodies was 1/104 (0.96%), using an ELISA test and an indirect immunofluorescence assay. Panstrongylus geniculatus and Rhodnius pictipes adults were found. The index case is autochthonous from San Pedro de Shishita, but the source of transmission is unknown.
Grupo Temático de Enfermedades Metaxénicas, Dirección General de Epidemiología, Ministerio de Salud, Lima, Perú.
Rufino
R
Cabrera
Silvia
S
Vega
Abraham G
AG
Cáceres
A César
AC
Ramal
Carlos
C
Alvarez
Pedro
P
Ladera
Raul
R
Pinedo
Gladys
G
Chuquipiondo
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007199:Indians, South American / Q000706:statistics & numerical data*; D007223:Infant; D007231:Infant, Newborn; D007303:Insect Vectors; D008297:Male; D008875:Middle Aged; D010203:Panstrongylus; D010568:Peru / Q000453:epidemiology; D012239:Rhodnius; D016036:Seroepidemiologic Studies; D014349:Trypanosoma cruzi / Q000276:immunology*; D055815:Young Adult
D000913:Antibodies, Protozoan