Synthesis of sulfur-sulfur bond formation from thioamides promoted by 2,3-dichloro-5,6-dicyanobenzoquinone.
A mild and efficient synthesis of sulfur-sulfur bond formation from thioformanilides with 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) is described. Functionality on the aromatic ring plays a key role in the formation of a sulfur-sulfur bond.
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 807, Taiwan.
Wei-Sheng
WS
Lo
Wan-Ping
WP
Hu
Hsiao-Ping
HP
Lo
Chung-Yu
CY
Chen
Chai-Lin
CL
Kao
Jaya Kishore
JK
Vandavasi
Jeh-Jeng
JJ
Wang
D016227:Benzoquinones / Q000737:chemistry* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D019281:Dimerization; D004220:Disulfides / Q000737:chemistry; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013455:Sulfur / Q000737:chemistry*; D013854:Thioamides / Q000737:chemistry*
D016227:Benzoquinones; D004220:Disulfides; D013854:Thioamides; C000928:dichlorodicyanobenzoquinone; D013455:Sulfur