Robotic-assisted laparoscopic ovarian tissue transplantation.
OBJECTIVE
To describe a technique for frozen-banked ovarian tissue transplantation using robotic-assisted laparoscopy.


METHODS
Case study.


METHODS
Academic tertiary care center.


METHODS
A 38-year-old patient in remission for non-Hodgkin lymphoma, whose ovarian tissue had been frozen for 3 years.


METHODS
Robotic-assisted laparoscopic transplantation of thawed ovarian cortical tissue to the remaining ovary and peritoneum.


METHODS
Resumption of spontaneous menses, follicular development, and ovulation as demonstrated by ultrasound, and serum E(2) and P levels.


RESULTS
The patient experienced cyclic spontaneous menstruation 6 months after the transplantation. Ovulation was confirmed by ultrasound and serum E(2) and P levels at month 11 after surgery.


CONCLUSIONS
Robotic-assisted laparoscopic surgery may be a good, minimally invasive alternative for the ovarian tissue transplantation procedure to restore ovarian function.
Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Munire Erman
ME
Akar
Alberto J
AJ
Carrillo
Jamie L
JL
Jennell
Tamer M
TM
Yalcinkaya
D000328:Adult; D015925:Cryopreservation; D005260:Female; D005298:Fertility; D006801:Humans; D010535:Laparoscopy / Q000295:instrumentation / Q000379:methods*; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy*; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation / Q000379:methods; D016377:Organ Transplantation / Q000295:instrumentation / Q000379:methods*; D010053:Ovary / Q000637:transplantation*; D012074:Remission Induction; D012371:Robotics; D014182:Transplantation, Autologous