Uterine artery Doppler and prediction of preeclampsia.
Identifying patients at risk for preeclampsia would allow an increase in perinatal surveillance and possibly decrease the inherent maternal and fetal morbidity and mortality associated with severe preeclampsia and eclampsia. First and second trimester uterine artery Doppler velocimetry is a sensitive screening tool for the detection of preeclampsia and intrauterine growth retardation (IUGR) requiring delivery before 34 weeks. The performance of uterine artery Doppler velocimetry as a screening test depends on the prevalence of the adverse outcome in the studied population and whether the adverse outcomes are assessed individually or collectively as a group. Future research in this area should focus on identification of additional markers that may be incorporated into a prediction model for early identification of patients at risk for adverse outcomes.
Department of Obstetrics and Gynecology, UCDHSC, Aurora, Colorado, USA.
Todd R
TR
Lovgren
Lorraine
L
Dugoff
Henry L
HL
Galan
D015415:Biomarkers / Q000097:blood; D005260:Female; D037161:Galectins / Q000097:blood; D006801:Humans; D007223:Infant; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000097:blood; D011264:Pregnancy Trimesters; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D055988:Uterine Artery / Q000000981:diagnostic imaging*
D015415:Biomarkers; D037161:Galectins; C038195:LGALS13 protein, human; D011257:Pregnancy Proteins; D011266:Pregnancy-Associated Plasma Protein-A