The first case of catheter-related bloodstream infection caused by Nocardia farcinica.
Nocardia farcinica is an emerging pathogen in immunocompromised hosts. Even though several species of Nocardia have been reported as causative pathogens of catheter-related blood stream infections (CRBSI), CRBSI caused by N. farcinica has not been reported. A 70-yr-old man with a tunneled central venous catheter (CVC) for home parenteral nutrition was admitted with fever for two days. Norcardia species was isolated from the blood through CVC and peripheral bloods and identified to N. farcinica by 16S rRNA and rpoB gene sequence analyses. This report emphasizes the rapid and correct identification of causative agents in infectious diseases in the selection of antimicrobial agents and the consideration of catheter removal.
Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
Sang Taek
ST
Heo
Kwan Soo
KS
Ko
Ki Tae
KT
Kwon
Seong Yeol
SY
Ryu
In Gyu
IG
Bae
Won Sup
WS
Oh
Jae-Hoon
JH
Song
Kyong Ran
KR
Peck
D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001769:Blood / Q000382:microbiology; D055499:Catheter-Related Infections / Q000175:diagnosis* / Q000382:microbiology / Q000451:nursing; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009615:Nocardia / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000175:diagnosis*; D010288:Parenteral Nutrition / Q000451:nursing; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000235:genetics / Q000378:metabolism; D017422:Sequence Analysis, DNA
D001426:Bacterial Proteins; D012336:RNA, Ribosomal, 16S