[Epidemic strain of methicillin-resistant Staphylococcus aureus in hospitals of Saint-Petersburg].
OBJECTIVE
To study genetic characteristics of methicillin-resistant Staphylococcus aureus (MRSA) causing nosocomial infections in specialized inpatient clinics of Saint-Petersburg.


METHODS
Nine cultures of S. aureus, which caused nosocomial infections in patients of 3 clinics in Saint-Petersburg, were studied by pulse-electrophoresis and spa-sequence typing. Identification of superantigens' genes pvl, sea, seb, sec, tst was performed by PCR.


RESULTS
Circulation of epidemic clone BT2007 attributed to spa-type t008 was revealed. According to pulse-electrotype, this epidemic clone was related with European epidemic clones of widespread cluster A.


CONCLUSIONS
Epidemiologic surveillance for MRSA should incorporate monitoring of clonal structure of the agent on both local (intra-clinic) and regional level.
A E
AE
Goncharov
B
B
Olsson-Liljequist
L P
LP
Zueva
V V
VV
Kolodzhieva
V Iu
VIu
Khoroshilov
N V
NV
Satosova
D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D005798:Genes, Bacterial / Q000235:genetics; D006786:Hospitals, Urban; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D012426:Russia / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D018089:Superantigens / Q000235:genetics; D014505:Urban Population
D018089:Superantigens