Fiber's impact on high-sensitivity C-reactive protein levels in cardiovascular disease.
OBJECTIVE
To determine if increased dietary or supplemental intake of fiber slows or prevents inflammation as evidenced by high-sensitivity C-reactive protein (hs-CRP) values.


METHODS
CINAHL, Medline, Health Source, Nursing/Academic Edition, and the Cochrane Library.


CONCLUSIONS
Evidence from this review suggested significant associations between fiber consumption and decreased risk for cardiovascular (CV) disease as evidenced by a decrease in hs-CRP levels. Six of the seven articles reviewed showed statistically significant decreases in hs-CRP levels as dietary fiber was increased.


CONCLUSIONS
Fiber in the diet may play a strong role in CV health as evidenced by six clinical trials completed using amount of fiber intake in relation to inflammation, particularly hs-CRP levels. Patients need to be educated to adhere to a high fiber diet, either by dietary or supplemental means, using the recommended 25-30 g of fiber per day.
Utah Valley Urgent Care, Provo, Utah, USA.
Jennifer L
JL
Butcher
Renea L
RL
Beckstrand
D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000187:drug effects / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D017281:Cost of Illness; D004043:Dietary Fiber / Q000008:administration & dosage / Q000494:pharmacology; D005247:Feeding Behavior; D006801:Humans; D007249:Inflammation; D018673:Nutrition Policy; D009765:Obesity / Q000150:complications; D012107:Research Design; D012307:Risk Factors; D040242:Risk Reduction Behavior; D014481:United States / Q000453:epidemiology
D015415:Biomarkers; D004043:Dietary Fiber; D002097:C-Reactive Protein