[Optimization of extraction conditions for semi-bionic extraction of Guizhi Fuling pill decoction by uniform design].
OBJECTIVE
To optimize the extraction conditions for semi-bionic extraction of Guizhi Fuling pill decoction.


METHODS
The best extraction condition of the semi-bionic extraction for Guizhi Fuling pill decoction was optimized by uniform design was optimized with paeoniflorin, cinnamic acid, laetrile, pachymic acid, total polysaccharose and dry extract as the indexes.


RESULTS
The optimized extraction condition is that extracting for 3 times with solvent pH values of 4.98, 7.35 and 8.00, respectively, and the total extracting time was 4.99 h.


CONCLUSIONS
In consideration of manufacturing fact, the pH value of thrice extractions is set at 5.0, 7.5, 8.0 respectively, and the extracting time is 2.0, 1.5, 1.5 h in turn.
Shanxi Provincial Academy of Traditional Chinese Medicine, Xi'an 710003, China. amelia@126.com
Fang
F
Li
Zhaowang
Z
Zhang
Xiumei
X
Sun
Weifeng
W
Wang
Meifang
M
Ma
D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration
D004365:Drugs, Chinese Herbal; C528663:guizhi decoction