Prepolymerized vs. in situ-polymerized fiber-reinforced composite implants--a pilot study.
The aim of this study was to investigate bone response to bioactive fiber-reinforced composite (FRC) implants under two polymerization conditions. Glass-fiber-dimethacrylate composite was tested as prepolymerized cylinder-shaped FRC implants and as cylindrical FRC implants polymerized in situ with blue light transmitted and scattered by the glass fibers. Ten FRC implants (6 prepolymerized and 4 in situ-polymerized implants) were placed in the right tibias of 3 pigs by means of a press-fit technique. After 12 weeks, light microscopy revealed only mild foreign-body reaction, with no accumulation of inflammatory cells on both the prepolymerized and the in situ-polymerized implants. The prepolymerized implants appeared to be fully integrated, whereas the in situ-polymerized implants were almost completely surrounded by a fibrous capsule. The present study suggests that in situ polymerization of FRC implants results in fibrous capsule formation and prevents integration with bone.
Department of Prosthetic Dentistry, University of Gothenburg, Sweden. ahmbal@utu.fi
A M
AM
Ballo
T O
TO
Närhi
E A
EA
Akca
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T
Ozen
S M
SM
Syrjänen
L V J
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Lassila
P K
PK
Vallittu
D000818:Animals; D003188:Composite Resins / Q000737:chemistry* / Q000528:radiation effects; D015921:Dental Implants; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology; D005898:Glass; D020007:Implants, Experimental; D055115:Light-Curing of Dental Adhesives / Q000009:adverse effects* / Q000379:methods; D008422:Materials Testing; D016348:Osseointegration / Q000528:radiation effects*; D010865:Pilot Projects; D011897:Random Allocation; D013552:Swine; D013977:Tibia / Q000601:surgery
D003188:Composite Resins; D015921:Dental Implants; C009753:fiberglass