TBHP/I2-mediated domino oxidative cyclization for one-pot synthesis of polysubstituted oxazoles.
A facile type of one-pot, transition-metal-free domino process was developed for the synthesis of oxazoles. Thus, a variety of polysubstituted oxazoles were easily synthesized via t-BuOOH/I(2)-mediated domino oxidative cyclization from readily available starting materials under mild conditions.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China. jianghf@scut.edu.cn
Huanfeng
H
Jiang
Huawen
H
Huang
Hua
H
Cao
Chaorong
C
Qi