Pure word deafness associated with extrapontine myelinolysis.
Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may involve separate thalamocortical pathways.
Department of Neurology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Ren-jing
RJ
Zhu
Zhi-su
ZS
Lv
Chun-lei
CL
Shan
Ming-wei
MW
Xu
Ben-yan
BY
Luo
D000328:Adult; D001037:Aphasia / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006313:Hearing Loss, Central / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D017590:Myelinolysis, Central Pontine / Q000150:complications* / Q000175:diagnosis*