Acute myelomonocytic leukemia (AML-M4) in a dog with the extradural lesion.
A two-year-old dog having presented with neurological signs showed marked leukocytosis and appearance of blast cells in the peripheral blood. Hematological and bone marrow examination showed an increase in blasts having both myeloid and monocytic cells characteristics. The dog was diagnosed with acute myelomonocytic leukemia (AML-M4) on the basis of bone marrow findings. Although the dog was treated with a multi-combination chemotherapy, the neurological abnormalities progressed and the dog was euthanized. Myelographic examination and necropsy revealed the extradural lesion formed by AML-M4 around the cervical spinal cord and this lesion was considered as a cause of the neurological signs.
Nakayama Veterinary Hospital, Nara.
Akiyoshi
A
Hayashi
Hiroshi
H
Tanaka
Masahiko
M
Kitamura
Hidetaka
H
Nishida
Tetsuya
T
Shimoda
Fumihito
F
Ohashi
Masanari
M
Nakayama
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D015479:Leukemia, Myelomonocytic, Acute / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008297:Male
D000970:Antineoplastic Agents