What are the similarities between stress, sudden cardiac death in Gallus gallus and sudden unexpected death in people with epilepsy.
Individuals with epilepsy are at higher risk of sudden unexpected death in epilepsy (SUDEP), responsible for 7.5% to 17% of all deaths in epilepsy. Many factors are current associated with SUDEP and possible effect of stress and cardiac arrhythmia are still not clear. Sudden death syndrome (SDS) in chickens is a disease characterized by an acute death of well-nourished and seeming healthy Gallus gallus after abrupt and brief flapping of their wings, similar to an epileptic seizure, with an incidence estimated as 0.5 to 5% in broiler chickens. A variety of nutritional and environmental factors have been included: but the exactly etiology of SDS is unknown. Studies had suggested that the hearts of broiler chickens are considerably more susceptible to arrhythmias and stress may induce ventricular arrhythmia and thus, sudden cardiac death. In this way, SDS in Gallus gallus could be an interesting model to study SUDEP.
Experimental Neurology, Paulist School of Medicine, São Paulo Federal University, São Paulo, SP, Brazil. scorza.nexp@epm.br
Fulvio A
FA
Scorza
Ricardo de
Rd
Albuquerque
Ricardo M
RM
Arida
Marly de
Md
Albuquerque
Vera C
VC
Terra
Hélio R
HR
Machado
Roberta M
RM
Cysneiros
Carla A
CA
Scorza
Esper A
EA
Cavalheiro
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000150:complications*; D002645:Chickens; D003645:Death, Sudden / Q000209:etiology*; D016757:Death, Sudden, Cardiac / Q000662:veterinary; D004827:Epilepsy / Q000150:complications*; D006801:Humans; D013315:Stress, Psychological / Q000150:complications*