Ciliary trafficking: CEP290 guards a gated community.
A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.
Department of Microbiology, Molecular Biology and Biochemistry, MMBB LSS142, University of Idaho, Moscow, ID 83844-3052, USA. ebetleja@vandals.uidaho.edu
Ewelina
E
Betleja
Douglas G
DG
Cole
D002696:Chlamydomonas / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D002923:Cilia / Q000378:metabolism* / Q000648:ultrastructure; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D021381:Protein Transport / Q000235:genetics*
D008565:Membrane Proteins; D010940:Plant Proteins