Uterine tumors: comparison of 3D versus 2D T2-weighted turbo spin-echo MR imaging at 3.0 T--initial experience.
OBJECTIVE
To compare a three-dimensional (3D) T2-weighted turbo spin-echo (TSE) magnetic resonance (MR) sequence (VISTA; Philips Medical Systems, Best, the Netherlands) with a two-dimensional (2D) T2-weighted TSE sequence in terms of image quality, signal intensity (SI) difference ratios, conspicuity, and staging of uterine tumors.


METHODS
This retrospective study was approved by the institutional review board, and informed consent was waived. Sixty-one women (mean age, 53.0 years ± 13.7 [standard deviation]; range, 30-87 years) with cervical carcinoma (n = 28), endometrial carcinoma (n = 21), or leiomyoma (n = 30) of the uterus were included. Patients underwent T2-weighted MR imaging at 3 T with both 1-mm-thick 3D and 5-mm-thick 2D T2-weighted TSE sequences. Three-dimensional T2-weighted TSE images were reconstructed at 5-mm thickness with the aid of a workstation. Quantitative analyses of signal-to-noise ratio (SNR) and SI difference ratios between tumors and other tissues and qualitative analyses of image quality and tissue conspicuity were performed. Two radiologists independently assessed local-regional staging for carcinomas. Quantitative values, qualitative scores, and tumor staging were analyzed by using the paired t test, Wilcoxon signed rank test, and McNemar test, respectively.


RESULTS
Mean myometrial SNR was higher on 3D than 2D images (14.3 vs 9.8; P < .0001). Mean SI difference ratios between cervical (0.45 vs 0.34; P < .0001) or endometrial (0.46 vs 0.40; P = .044) carcinomas and gluteal muscle were higher on 3D images, but those between leiomyoma and myometrium (0.33 vs 0.43; P < .0001) were lower than those on 2D images. Image quality (P = .0004) and carcinoma conspicuity (P < .0005) were superior with the 3D T2-weighted TSE sequence. Although multiplanar reconstruction of 3D T2-weighted TSE images was useful for staging in one case, there were no significant differences between 3D and 2D T2-weighted TSE imaging in accuracy of staging for the two readers for cervical or endometrial carcinoma.


CONCLUSIONS
The 3D T2-weighted TSE sequence showed certain advantages over the 2D T2-weighted TSE sequence, and it has the potential to improve the performance of MR imaging for the evaluation of uterine carcinoma.
Department of Radiology, Osaka University Graduate School of Medicine, D1, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan. mhori@radiol.med.osaka-u.ac.jp
Masatoshi
M
Hori
Tonsok
T
Kim
Hiromitsu
H
Onishi
Takashi
T
Ueguchi
Mitsuaki
M
Tatsumi
Atsushi
A
Nakamoto
Takahiro
T
Tsuboyama
Kaname
K
Tomoda
Noriyuki
N
Tomiyama
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007889:Leiomyoma / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology
D003287:Contrast Media