The association of preoperative thrombocytosis with prognostic factors in malign ovarian tumor.
OBJECTIVE
We assessed the association of preoperative thrombocytosis with prognostic factors in malign ovarian tumor.


METHODS
Over a five-year period, cases treated for ovarian cancer were randomly assigned. The data were collected from gynecological oncology, radiation oncology, medical oncology and pathology departments. Statistical analyses were carried out by using the statistical packages for SPSS 12.0 for Windows (Chicago, IL, USA). Survival was analyzed by the method of Kaplan and Meier, using log-rank (Mantel-Cox) analysis.


RESULTS
51 cases with ovarian cancer were evaluated. Cases with thrombocytosis were found to have greater CA-125 levels, more advanced stage disease, more ascites and shorter periods of survival.


CONCLUSIONS
Thrombocytosis is a poor prognostic factor in ovarian cancer. As reported previously, it is associated with aggressive tumor biology. Thus, preoperative thrombocytosis can be a used as a marker of poor outcomes.
Department of Obstetrics and Gynecology, Dicle University, Faculty of Medicine, Diyarbakir, Turkey.
U
U
Kuyumcuoglu
A I
AI
Guzel
Y
Y
Celik
M
M
Erdemoğlu
D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology; D011379:Prognosis; D012189:Retrospective Studies; D013922:Thrombocytosis / Q000150:complications*