Outcomes following pharyngolaryngectomy reconstruction with the anterolateral thigh (ALT) free flap.
We retrospectively reviewed 15 cases of pharyngolaryngectomy for advanced laryngeal carcinoma reconstructed with the anterolateral thigh (ALT) free flap. Thirteen patients had primary surgery and adjuvant treatment (radiotherapy or chemoradiotherapy), and two had salvage surgery. Thirteen had stage III or IV disease, and eight had cervical nodal extracapsular spread. In this series all the flaps survived, and at median follow-up of 14.5 months (range 3.7-31.2), 12 of the 15 patients were alive. One patient developed a chronic pharyngocutaneous fistula, and five required repeat balloon dilatations for late pharyngeal strictures. Six patients enjoyed restoration of full oral intake, seven were able to take a soft diet, and two were dependent on feeding by percutaneous endoscopic gastrostomy. Four patients developed adequate tracheo-oesophageal speech, and one successfully developed oesophageal speech. In this series many of the surgical problems associated with pharyngolaryngectomy reconstruction were addressed successfully by the ALT, but late dysphagia remained troublesome in an appreciable minority. While adjuvant radiotherapy could have contributed to this, future innovations will focus on the reduction of late strictures.
Regional Maxillofacial Unit, University Hospital Aintree, L9 7AL Liverpool, United Kingdom. mhwsdr@yahoo.com
M W
MW
Ho
L
L
Houghton
E
E
Gillmartin
S R
SR
Jackson
J
J
Lancaster
T M
TM
Jones
T K
TK
Blackburn
J J
JJ
Homer
S
S
Loughran
F M
FM
Ascott
R J
RJ
Shaw
D000368:Aged; D002277:Carcinoma / Q000556:secondary / Q000601:surgery; D002404:Catheterization; D015331:Cohort Studies; D003251:Constriction, Pathologic / Q000209:etiology / Q000628:therapy; D017577:Cutaneous Fistula / Q000209:etiology; D003680:Deglutition Disorders / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D058752:Free Tissue Flaps; D005774:Gastrostomy; D006085:Graft Survival; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery; D007825:Laryngectomy / Q000534:rehabilitation*; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010288:Parenteral Nutrition; D010608:Pharyngeal Diseases / Q000209:etiology / Q000628:therapy; D010611:Pharyngectomy / Q000534:rehabilitation*; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D016156:Respiratory Tract Fistula / Q000209:etiology; D012189:Retrospective Studies; D013072:Speech, Esophageal; D013848:Thigh / Q000601:surgery; D016896:Treatment Outcome