Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project.
This article proposes the establishment of a United States-Israel Longitudinal Database for Healthy Aging and Preclinical Dementia as a prototype model for the eventual creation of an international database. It is envisioned that such a comprehensive international database, as a shared research resource, will provide the foundation for a systems approach to solve the dual public health problems of: (1) Early detection of individuals at an elevated risk of developing Alzheimer's disease, and (2) Developing interventions to delay onset of, or prevent, chronic brain disorders later in life.
Campaign to Prevent Alzheimer's Disease by 2020 (PAD2020), Rockville, MD, USA. ara@pad2020.org
Ara S
AS
Khachaturian
Joab
J
Chapman
Lindsay
L
Farrer
Robert P
RP
Friedland
Richard
R
Ebstein
Iris
I
Grossman
Talma
T
Hendler
Bruce
B
Hermann
Rivka
R
Inzelberg
Sterling
S
Johnson
Zaven S
ZS
Khachaturian
Irit
I
Lichter-Shapira
Oksana
O
Makeeva
Robin
R
Mayrl
Eli
E
Mizrahi
Allen D
AD
Roses
Mark
M
Sager
Shifra
S
Fraifeld
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000544:Alzheimer Disease / Q000191:economics / Q000453:epidemiology* / Q000517:prevention & control*; D019992:Databases as Topic / Q000191:economics / Q000458:organization & administration* / Q000639:trends*; D016208:Databases, Factual / Q000191:economics / Q000592:standards / Q000639:trends*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007391:International Cooperation; D007557:Israel / Q000453:epidemiology; D008137:Longitudinal Studies / Q000191:economics / Q000379:methods / Q000592:standards; D008297:Male; D008609:Mental Status Schedule; D012042:Registries; D014481:United States / Q000453:epidemiology