LC/MS data processing for label-free quantitative analysis.
In this chapter, we describe the use of SuperHirn and MSight, two complementary tools developed to the processing of label-free LC/MS data in view of the quantitation of proteomics samples. While MSight is mainly dedicated to the visualisation and navigation into LC/MS data, SuperHirn is specialised in peak detection, normalisation and alignment of LC/MS runs. These two tools can be used in a complementary way and one of the possible usages is described here.
Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland.
Patricia M
PM
Palagi
Markus
M
Müller
Daniel
D
Walther
Frédérique
F
Lisacek
D002853:Chromatography, Liquid / Q000379:methods*; D030562:Databases, Protein; D013058:Mass Spectrometry / Q000379:methods*; D011506:Proteins / Q000032:analysis*; D012984:Software; D013194:Staining and Labeling; D013223:Statistics as Topic
D011506:Proteins