Transdermal fluid loss in severely burned patients.
BACKGROUND
The skin protects against fluid and electrolyte loss. Burn injury does affect skin integrity and protection against fluid loss is lost. Thus, a systemic dehydration can be provoked by underestimation of fluid loss through burn wounds.


OBJECTIVE
We wanted to quantify transdermal fluid loss in burn wounds.


METHODS
Retrospective study. 40 patients admitted to a specialized burn unit were analyzed and separated in two groups without (Group A) or with (Group B) hypernatremia. Means of daily infusion-diuresis-ratio (IDR) and the relationship to totally burned surface area (TBSA) were analyzed.


RESULTS
In Group A 25 patients with a mean age of 47 ± 18 years, a mean TBSA of 23 ± 11%, and a mean abbreviated burned severity index (ABSI) score of 6.9 ± 2.1 were summarized. In Group B 15 patients with a mean age of 47 ± 22 years, a mean TBSA of 30 ± 13%, and a mean ABSI score of 8.1 ± 1.7 were included. Statistical analysis of the period from day 3 to day 6 showed a significant higher daily IDR-amount in Group A (Group A vs. Group B: 786 ± 1029 ml vs. -181 ± 1021 ml; p<0.001) and for daily IDR-TBSA-ratio (Group A vs. Group B: 40 ± 41 ml/% vs. -4 ± 36 ml/%; p<0.001).


CONCLUSIONS
There is a systemic relevant transdermal fluid loss in burn wounds after severe burn injury. Serum sodium concentration can be used to calculate need of fluid resuscitation for fluid maintenance. There is a need of an established fluid removal strategy to avoid water and electrolyte imbalances.
Department of Plastic Surgery, Hand Surgery, Burn Unit, University Hospital Schleswig-Holstein, Lübeck, Germany. thomas.namdar@uk-sh.de
Thomas
T
Namdar
Peter L
PL
Stollwerck
Felix H
FH
Stang
Frank
F
Siemers
Peter
P
Mailänder
Thomas
T
Lange
D000293:Adolescent; D000328:Adult; D000368:Aged; D002056:Burns / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D012867:Skin / Q000503:physiopathology*; D012964:Sodium / Q000097:blood; D014870:Water Loss, Insensible; D014883:Water-Electrolyte Imbalance / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*
D012964:Sodium