Atrioventricular block and diastolic dysfunction in a patient with Sanfilippo C.
A 39-year-old woman with Sanfilippo C syndrome was referred to our department for the treatment of bradycardia. An electrocardiogram revealed a second degree atrioventricular block, and pacemaker implantation was performed with the patient under general anesthesia. A transthoracic echocardiogram showed normal left ventricular systolic function, moderate mitral regurgitation due to mitral valve prolapse, and a high E/e' ratio, indicating left ventricular diastolic dysfunction. The present patient exhibited a rare case of Sanfilippo syndrome complicated with conduction disturbances, mitral regurgitation, and diastolic dysfunction.
Department of Cardiology, Kumamoto Saishunsou Hospital, Koushi. misumi@saisyunsou1.hosp.go.jp
Ikuo
I
Misumi
Shoji
S
Chikazawa
Takateru
T
Ishitsu
Shigenori
S
Higuchi
Tomoyuki
T
Shimazu
Chizuru
C
Ikeda
Mariko
M
Uchino
Yoshihiro
Y
Shibata
Kenji
K
Ebihara
Ryuichiro
R
Akahoshi
D000328:Adult; D054537:Atrioventricular Block / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D003971:Diastole / Q000502:physiology; D005260:Female; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D009084:Mucopolysaccharidosis III / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology