Surface molecular imprinting onto fluorescein-coated magnetic nanoparticles via reversible addition fragmentation chain transfer polymerization: a facile three-in-one system for recognition and separation of endocrine disrupting chemicals.
In this study, we present a general protocol for the making of surface-imprinted magnetic fluorescence beads via reversible addition-fragmentation chain transfer polymerization. The resulting composites were characterized by X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, fluorescence spectroscopy, Fourier transform infrared spectroscopy, and energy dispersive spectroscopy. The as-synthesized beads exhibited homogeneous polymer films (thickness of about 5.7 nm), spherical shape, high fluorescence intensity and magnetic property (Magnetization (Ms)=3.67 emu g(-1)). The hybrids bind the original template 17β-estradiol with an appreciable selectivity over structurally related compounds. In addition, the resulting hybrids performed without obvious deterioration after five repeated cycles. This study therefore demonstrates the potential of molecularly imprinted polymers for the recognition and separation of endocrine disrupting chemicals.
Department of Chemistry, Harbin Institute of Technology, Harbin, 150090, China.
Ying
Y
Li
Cunku
C
Dong
Jia
J
Chu
Jingyao
J
Qi
Xin
X
Li
D052244:Endocrine Disruptors / Q000737:chemistry* / Q000302:isolation & purification; D004958:Estradiol / Q000737:chemistry / Q000302:isolation & purification; D052203:Ferrosoferric Oxide / Q000737:chemistry; D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry*; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D054802:Molecular Imprinting / Q000379:methods*; D058105:Polymerization; D012822:Silicon Dioxide / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D017550:Spectroscopy, Fourier Transform Infrared
D052244:Endocrine Disruptors; D004958:Estradiol; D012822:Silicon Dioxide; D016650:Fluorescein-5-isothiocyanate; D052203:Ferrosoferric Oxide