[Preparation and quality evaluation of fufangxiaoyepipa dispersible tablets].
OBJECTIVE
To study the preparation of fufangxiaoyepipa dispersible tablets and evaluate its quality.


METHODS
Using the disintegration time as index to screen out the best prescription of the dispersible tablets by orthogonal design.


RESULTS
The prescription assembly was 40% of extraction, 15% of MCC, 18% of CCMC-Na, 25% of Calcium sulfate, 2% of Magnesium stearate, the disintegration time met the provision of Pharmacopoeia.


CONCLUSIONS
The dispersible tablets dissolve faster and disperse uniformly and the dissolution percent in vitro is obviously superior to the conventional tablets, improving the bioavailability of the preparation.
College of Pharmacy, Lanzhou University, Lanzhou 730000, China. Makeitpei@163.com
Pei
P
Zhao
Lan-Lan
LL
Li
Xiao-Yu
XY
Yang
Hai-Sheng
HS
Jiao
D000704:Analysis of Variance; D002133:Calcium Sulfate / Q000008:administration & dosage* / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry*; D031983:Eriobotrya / Q000737:chemistry; D005079:Excipients; D005419:Flavonoids / Q000032:analysis; D008747:Methylcellulose / Q000008:administration & dosage* / Q000737:chemistry; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D015203:Reproducibility of Results; D012995:Solubility; D013607:Tablets; D013678:Technology, Pharmaceutical / Q000379:methods*
D004365:Drugs, Chinese Herbal; D005079:Excipients; D005419:Flavonoids; D013607:Tablets; C038044:baicalin; D008747:Methylcellulose; D002133:Calcium Sulfate