Initiation and propagation of neurodegeneration.
Although substantial progress has been made in understanding the molecular and pathological bases of neurodegeneration, there have been few successes in the clinic and a number of fundamental questions remain unanswered. Is this skepticism misplaced, or do the words of Sir Isaac Newton hold true, that "what we know is a drop, what we don't know is an ocean"?
DZNE-German Center for Neurodegenerative Diseases, Munich, Germany. chaass@med.uni-muenchen.de
Christian
C
Haass
D000682:Amyloid / Q000633:toxicity; D000818:Animals; D002986:Clinical Trials as Topic; D018450:Disease Progression; D004777:Environment; D006801:Humans; D008954:Models, Biological; D009410:Nerve Degeneration / Q000209:etiology* / Q000473:pathology*; D009498:Neurotoxins / Q000633:toxicity; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D057170:Translational Research, Biomedical
D000682:Amyloid; D009498:Neurotoxins