The risk of local recurrence along the core-needle biopsy tract in patients with bone sarcomas.
BACKGROUND
We evaluated the local recurrence rate (LRR) of bone sarcoma along the core-needle biopsy (CNB) tract in patients who underwent limb Salvage Surgery (LSS) following a diagnostic CNB performed irrespective of the planned surgical incision site and for which surgery did not involve any biopsy tract removal.


METHODS
A retrospective review of 10 pediatric patients diagnosed with bone sarcoma using a computed tomography-guided core-needle biopsy, with evaluation of medical records, pathological specimens and radiological films from the date of diagnosis until the most recent follow-up.


RESULTS
None of the patients experienced local recurrence during their follow up, despite the lack of biopsy site resection. CT scans of the involved extremities were negative for any suspicious lesions in all patients up until the most recent follow-up.


CONCLUSIONS
Our study and review of the literature suggest that the incidence of tumor seeding the CNB tract in bone sarcoma patients is apparently low, and possibly negligible. CNB should be performed through the most direct approach to the tumor, and LSS can be performed safely through the standard approaches without excision of the biopsy tract.
Department of Surgery, Division of Orthopaedic Surgery, American University of Beirut Medical Center, Beirut, Lebanon. ss15@aub.edu.lb
Said
S
Saghieh
Karim Z
KZ
Masrouha
Khaled M
KM
Musallam
Rami
R
Mahfouz
Miguel
M
Abboud
Nabil J
NJ
Khoury
Rachid
R
Haidar
D000293:Adolescent; D001707:Biopsy, Needle / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed