Evaluation of the comparability and repeatability of four wavefront aberrometers.
OBJECTIVE
To compare total ocular aberrations and corneal aberrations identified with four different aberrometers and to determine the repeatability and interobserver variability.


METHODS
In this prospective comparative study, 23 healthy subjects underwent bilateral examination with four aberrometers: the Irx3 (Hartmann-Shack; Imagine Eyes, Orsay, France), Keratron (Hartmann-Shack; Optikon, Rome Italy), iTrace (ray-tracing; Tracey Technologies, Houston, TX), and OPD-Scan (Automated Retinoscopy; Nidek, Gamagori, Japan). Six images per eye were obtained. Second-, third- and fourth-order spherical aberrations were exported for 5.0-mm pupils.


RESULTS
Significant differences in measurements were found for several total ocular aberrations (defocus [2,0], astigmatism [2,2], trefoil [3,-3], trefoil [3,3], and spherical aberration [4,0]) and corneal aberrations (defocus [2,0] and astigmatism [2,2]). The Irx3 showed the highest repeatability in measuring total ocular aberrations, followed by the Keratron, OPD-Scan, and iTrace. The repeatability of the corneal aberration measurements was highest for the iTrace, followed by the Keratron and OPD-Scan. The OPD-Scan showed a lower interobserver variability, compared with the Irx3, Keratron, and iTrace.


CONCLUSIONS
Total ocular and corneal aberrations are not comparable when measured with different aberrometers. Hartmann-Shack aberrometers showed the best repeatability for total ocular aberrations and iTrace for corneal aberrations. It would be worthwhile in the future to evaluate aberrometers in patients with more aberrant eyes.
University Eye Clinic, Maastricht University Medical Centre, Maastricht, The Netherlands.
Nienke
N
Visser
Tos T J M
TT
Berendschot
Frenne
F
Verbakel
Annelie N
AN
Tan
John
J
de Brabander
Rudy M M A
RM
Nuijts
D057128:Aberrometry / Q000295:instrumentation*; D000328:Adult; D057108:Corneal Wavefront Aberration / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011446:Prospective Studies; D015203:Reproducibility of Results; D055815:Young Adult