Universality in the evolution of orientation columns in the visual cortex.
The brain's visual cortex processes information concerning form, pattern, and motion within functional maps that reflect the layout of neuronal circuits. We analyzed functional maps of orientation preference in the ferret, tree shrew, and galago--three species separated since the basal radiation of placental mammals more than 65 million years ago--and found a common organizing principle. A symmetry-based class of models for the self-organization of cortical networks predicts all essential features of the layout of these neuronal circuits, but only if suppressive long-range interactions dominate development. We show mathematically that orientation-selective long-range connectivity can mediate the required interactions. Our results suggest that self-organization has canalized the evolution of the neuronal circuitry underlying orientation preference maps into a single common design.
Max-Planck-Institute for Dynamics and Self-Organization, Bernstein Center for Computational Neuroscience, Faculty of Physics, Göttingen University, D-37073 Göttingen, Germany. kaschube@princeton.edu
Matthias
M
Kaschube
Michael
M
Schnabel
Siegrid
S
Löwel
David M
DM
Coppola
Leonard E
LE
White
Fred
F
Wolf
D000818:Animals; D005075:Biological Evolution; D005289:Ferrets / Q000033:anatomy & histology; D005701:Galago / Q000033:anatomy & histology; D009474:Neurons / Q000166:cytology*; D014418:Tupaiidae / Q000033:anatomy & histology; D014793:Visual Cortex / Q000033:anatomy & histology* / Q000166:cytology