Malignant transformation of intracranial meningeal melanocytoma. Case report and review of the literature.
Meningeal melanocytoma is an uncommon pigmented neoplasm that affects the CNS and develops in the cranial and spinal leptomeninges. Here we report on a case of malignant transformation of intracranial supratentorial meningeal melanocytoma which recurred after 3 years as malignant melanoma. This case demonstrates that the biological behavior of melanocytoma is uncertain and that these lesions may recur as malignant melanoma.
Departments of Pathology Neurosurgery Radiology, Chinese PLA General Hospital, Beijing, China. wfl301@gmail.com
Fulin
F
Wang
Guangyu
G
Qiao
Xin
X
Lou
Xin
X
Song
Wei
W
Chen
D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003399:Craniotomy; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology*; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery; D013702:Temporal Lobe / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome