Retinal macroaneurysm associated with ocular sarcoidosis.
OBJECTIVE
To characterize retinal macroaneurysm, which although rare, has been reported as a specific complication of ocular sarcoidosis.


METHODS
Ninety-seven sarcoidosis patients with intraocular inflammation diagnosed at the Uveitis Clinic of Tokyo Medical University Hospital between 1997 and 2006 were analyzed retrospectively.


RESULTS
Retinal macroaneurysm was found in nine eyes of seven patients (7.2%). The mean patient age at onset was 61 years, similar to the reported onset age in patients with macroaneurysm not associated with ocular sarcoidosis. Most aneurysms developed in the chronic phase, and not in the early phase, of ocular sarcoidosis. Two patients (29%) were affected bilaterally. Five of nine eyes (56%) had multiple lesions. Unlike retinal macroaneurysm not associated with sarcoidosis, which is usually solitary and unilateral, rates of bilateral and multiple lesions were high.


CONCLUSIONS
The clinical features of retinal aneurysm associated with ocular sarcoidosis are considerably different from those of unilateral macroaneurysm not associated with sarcoidosis.
Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. katsyokoi@yahoo.co.jp
Katsutoshi
K
Yokoi
Masayo
M
Oshita
Hiroshi
H
Goto
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000783:Aneurysm / Q000175:diagnosis / Q000209:etiology*; D005128:Eye Diseases / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000150:complications*