The influence of exposure to Euphorbia splendens var. hislopii latex on the concentrations of total proteins and nitrogen products in Biomphalaria glabrata infected with Schistosoma mansoni.
The aim of this work was to analyze the content of total protein and nitrogen degradation products in Biomphalaria glabrata infected with Schistosoma mansoni and exposed to Euphorbia splendens var. hislopii latex. The LC(50) of this latex was 1.0mg/l. Concentrations of uric acid, urea and total proteins were determined in the hemolymph of B. glabrata infected with five S. mansoni miracidia and exposed to a sublethal concentration of E. splendens var. hislopii latex for 24h. The exposure to this molluscicide caused total depletion of the alterative sources of energy (total proteins) and significant variation in the nitrogen degradation products. The urea content increased while the uric acid level decreased. These results reflect a disturbance in the snails regulation of their metabolism due to intoxication caused by the latex exposure.
Laboratório de Esquistossomose Experimental, Instituto Oswaldo Cruz (IOC)- Fiocruz, Av, Brasil, 4365, 21045-900 Rio de Janeiro, RJ, Brazil. clelia@ioc.fiocruz.br
Clélia Christina
CC
Mello-Silva
Maurício Carvalho
MC
de Vasconcellos
José Clecildo Barreto
JC
Bezerra
Maria de Lurdes Azevedo
Mde L
Rodrigues
Jairo
J
Pinheiro
D000704:Analysis of Variance; D000818:Animals; D001700:Biomphalaria / Q000378:metabolism* / Q000469:parasitology*; D028481:Euphorbia / Q000737:chemistry*; D007928:Lethal Dose 50; D011506:Proteins / Q000032:analysis; D012550:Schistosoma mansoni / Q000472:pathogenicity*; D014508:Urea / Q000032:analysis; D014527:Uric Acid / Q000032:analysis
D011506:Proteins; D014527:Uric Acid; D014508:Urea