Iris metastasis from adenoid cystic carcinoma of parotid gland.
OBJECTIVE
The purposes of this study are to report the first case of parotid gland adenoid cystic carcinoma (ACC) metastatic to the iris and ciliary body and suggest a successful treatment option.


METHODS
A 64-year-old white man presented with a diffuse multilobulated amelanotic mass involving the peripheral iris and anterior chamber angle. Fine needle aspiration with a 27-gauge needle was performed, disclosing epithelial cells with positive staining for AE1/AE3 and morphologic features consistent with metastatic parotid gland ACC. Treatment with I plaque radiotherapy (40 Gy to the apex) was provided.


RESULTS
Five months later, the tumor remained regressed.


CONCLUSIONS
The systemic prognosis of salivary gland ACC is poor, with frequent local recurrences and late distance metastases. Even though uncommon, ocular metastases should be considered, and plaque radiotherapy may be useful to treat these patients.
Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA.
Javier
J
Montero
Carol L
CL
Shields
Carlos
C
Bianciotto
Jerry A
JA
Shields
Hormoz
H
Ehya
D001918:Brachytherapy; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy / Q000556:secondary*; D002924:Ciliary Body / Q000473:pathology; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D015811:Iris Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D014792:Visual Acuity
D007457:Iodine Radioisotopes