Serum adiponectin levels in patients with coronary artery disease.
BACKGROUND
Adiponectin is an adipocytokine secreted from white adipose tissue. Serum level of adiponectin has been shown to be reduced in several disease states like obesity and diabetes. Hypoadiponectinemia has also been included in the list of newer risk factors for Coronary Artery Disease (CAD).


METHODS
In this analytical cross-sectional study serum adiponectin level was measured by Enzyme Linked Immunosorbant Assay (ELISA) in 60 cases of coronary artery disease (CAD) (both sexes, aged 40-60 yrs) and 60 healthy controls.


RESULTS
Low levels of adiponectin were seen in CAD patients as well as controls. These levels were lower as compared to western standards.


CONCLUSIONS
Our study conforms to the previous observation of lower serum adiponectin levels in South Asians compared to the western standards. Serum adiponectin level should be considered in the laboratory work-up of CAD patients.
Department of Biochemistry, CMH Lahore Medical College, Lahore, Pakistan. iram_nadeem@yahoo.com
Iram
I
Fayyaz
M Zamir
MZ
Ahmed
Syed Imran
SI
Shah
Sadia
S
Mehmood
Shama
S
Akram
Mansoor
M
Ghani
D052242:Adiponectin / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood*; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans
D052242:Adiponectin