[A case of jejunal adenocarcinoma with serum DUPAN-2 elevation].
A 50-year-old woman was admitted to our hospital because of abdominal pain and vomiting. Ileus with ulcerated jejunal tumor was diagnosed and biopsy revealed adenocarcinoma. Because her serum level of DUPAN-2 was high, she was examined by PET scan, which revealed that she had a left ovarian mass in addition to the jejunal tumor. Surgical resection was performed: both tumors were adenocarcinoma, but the ovarian tumor was considered to be metastatic clinically and histologically. Immunostaining for DUPAN-2 was positive in the both tumors. The serum level of DUPAN-2 returned to normal after the surgery, and has been within normal limits for about 3 years without any additional therapy. This case shows a possible relation between small bowel adenocarcinoma and DUPAN-2.
Department of Gastroenterology and Hepatology, Tenri Hospital. yyamaga5@orion.ocn.ne.jp
Yuichi
Y
Yamaga
Masaya
M
Ohana
Takefumi
T
Nakamura
Shino
S
Kikuchi
Kayoko
K
Matsumura
Masahiro
M
Takita
Satoru
S
Iwamoto
Toshiyuki
T
Morisawa
Shinji
S
Miyajima
Hajime
H
Kida
Akihiro
A
Okano
Satoshi
S
Okinaga
Fusako
F
Kusumi
Hiroshi
H
Takakuwa
Gen
G
Honjou
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000601:surgery; D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood; D005260:Female; D006801:Humans; D007580:Jejunal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; C042317:DU-PAN-2 antigen, human