Recovery of ophthalmoplegia after endovascular treatment of intracranial aneurysms.
OBJECTIVE
Recovery of aneurysm induced CNP after endosaccular coiling has been reported in the literature. The aim of this study was to assess in detail the parameters that affect the outcome after endovascular treatment of ophthalmoplegic aneurysms due CNP.


METHODS
Between November 1999 and March 2008, 30 consecutive patients (8 men, 22 women; mean age, 54.9 years) presenting with CNP underwent endosaccular coiling with or without additional use of stents in the parent artery. Subarachnoid hemorrhage was present in 10 patients, whereas 20 patients had unruptured aneurysms. The mean size of the aneurysms was 10 mm. Initial CNP was complete in 11 patients and partial in 19. Mean follow-up after coiling was 19 months.


RESULTS
The mean interval between the onset of CNP and aneurysm embolization was 48 days. Fifteen patients (50%) had complete recovery of oculomotor function, 12 had incomplete recovery (40%), and 3 (10%) remained unchanged after treatment. In 4 aneurysms (13.3%), 1 additional embolization was performed, whereas in 4 other aneurysms, 2 additional embolization procedures were necessary. Procedure-related permanent morbidity occurred in 2 patients (6.6%).


CONCLUSIONS
Endosaccular coiling is an effective and safe method for the treatment of ophthalmoplegic aneurysms. Age, neck size, and time of treatment do not seem to constitute prognostic factors with respect to CNP recovery, though patients with small aneurysms, unruptured status, and/or location in the posterior circulation showed a tendency for better outcome. The degree of initial CNP was the only statistically significant prognostic factor concerning the final outcome, resulting in better recovery, in case of incomplete initial CNP.
Department of Diagnostic and Interventional Radiology, University Hospital of Essen, Germany.
V
V
Panagiotopoulos
S C
SC
Ladd
E
E
Gizewski
S
S
Asgari
E I
EI
Sandalcioglu
M
M
Forsting
I
I
Wanke
D020434:Abducens Nerve Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D003389:Cranial Nerve Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D015840:Oculomotor Nerve Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D009886:Ophthalmoplegia / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D020127:Recovery of Function; D012189:Retrospective Studies; D015607:Stents; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome; D020432:Trochlear Nerve Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D055815:Young Adult