Opioid-mediated drug actions cannot be concluded from naloxone induced reversal of anti-nociceptive effects in behavioural tests only.
Jörn
J
Lötsch
Irmgard
I
Tegeder
D000701:Analgesics, Opioid / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004723:Endorphins / Q000502:physiology; D009270:Naloxone / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D010146:Pain / Q000188:drug therapy* / Q000523:psychology*; D010147:Pain Measurement / Q000379:methods*; D051381:Rats
D000701:Analgesics, Opioid; D004723:Endorphins; D009292:Narcotic Antagonists; D009270:Naloxone