[Therapy-resistant, atrophic and septic femoral pseudarthrosis].
Non-union is a common and serious complication in orthopaedic surgery with high socioeconomic importance. In addition to conventional methods for the treatment of non-unions bone morphogenetic protein (BMP)-7 for the induction of bone tissue is available. The case report demonstrates successful treatment of a septic and atrophic femoral non-union by combination therapy with BMP-7 and autologous spongiosa graft after multiple revision surgeries.
Klinik für Orthopädie, Universität Duisburg-Essen, Deutschland. christian.wedemeyer@uni-duisburg-essen.de
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Wedemeyer
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Peppmüller
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Bredendiek
D055419:Bone Morphogenetic Protein 7 / Q000627:therapeutic use*; D002908:Chronic Disease; D005264:Femoral Fractures / Q000209:etiology* / Q000601:surgery*; D005593:Fracture Fixation, Internal / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011542:Pseudarthrosis / Q000188:drug therapy* / Q000209:etiology*; D012008:Recurrence
D055419:Bone Morphogenetic Protein 7