Myosin VI: how do charged tails exert control?
Molecular dynamics simulations and single molecule experiments are used to suggest that charged helices in the medial tail domain participate in myosin VI dimerization (Kim et al., 2010), which reinforces the mechanism that unfolding of the three helix bundle in the proximal tail serves as a lever arm extension.
Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742, USA. thirum@umd.edu
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