Seroprevalence of hepatitis B in outdoor female patients of reproductive age group at Ayub Teaching Hospital Abbottabad.
BACKGROUND
Hepatitis B is inflammation of the liver caused by a Hepatitis B virus, having a parenteral mode of entry and infecting millions of people around the world.


OBJECTIVE
The present study was planned to assess the seroprevalence of Hepatitis B in women of reproductive age in Hazara in order to promote disease prevention in the perinatal period by vaccination against Hepatitis B.


METHODS
Women 15-45 years old belonging to Hazara Division were included in this descriptive, cross-sectional study conducted over a period of one year at the Department of Microbiology, Ayub Medical College, Abbottabad in collaboration with the Department of Pathology, Ayub Teaching Hospital, Abbottabad from 1st March 2006 to 28th February 2007. Non-probability convenience sampling was done to select 500 females from those visiting Ayub Teaching Hospital Abbottabad as outdoor patients or accompanying person. History, examination, and serum alanine aminotransferase estimation were followed by the initial screening for Hepatitis B surface Antigen (HBsAg) using immunochromatographic device. Enzyme linked Immunosorbent assay was used to confirm the presence of HBsAg.


RESULTS
HBsAg was detected in 3% of the women. History of multiple injections was present in 100%, blood transfusion in 22%, dental procedure in 46% and surgical procedure in 43% of the subjects. Only 1% women had been vaccinated.


CONCLUSIONS
Seroprevalence of the Hepatitis B is not different from the figures reported by the studies previously conducted on general population in Pakistan. However it is different from those reported for the special groups.
Department of Pathology, Ayub Medical College, Abbottabad, Pakistan. jamlafarid62@yahoo.com
Jamila
J
Farid
Taher
T
Salim
Javed
J
Sarwar
Muhammad
M
Idris
Nasreen
N
Gul
Syed Humayun
SH
Shah
Muhammad
M
Suleman
D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D015995:Prevalence; D016036:Seroepidemiologic Studies; D055815:Young Adult