[The therapeutic effect of triamcinolone acetonide with Pingyangmycin on lymphatic malformations in oral and maxillofacial regions].
OBJECTIVE
To investigate the therapeutic effect of Triamcinolone Acetonide and Pingyangmycin on lymphatic malformations in oral and maxillofacial regions.


METHODS
29 patients with lymphatic malformations in oral and maxillofacial regions were divided into two groups to receive intra-lesion injection with Triamcinolone Acetonide and Pingyangmycin in experimental group, or with Pingyangmycin only in control group. The lesions involution and facial appearance were observed.


RESULTS
2 years after treatment, the volume of small cyst and micro-cyst type mass shrank to (3.7 +/- 0.3)% and (4.2 +/- 0.4)%, respectively in experimental group, while (15.4 +/- 1.3)% and (24.1 +/- 3.1)% in control group. The lesion involution was markedly obvious in experimental group. Compare with control group, the facial asymmetry was greatly improved in experimental group.


CONCLUSIONS
Intra-lesion injection with Triamcinolone Acetonide and Pingyangmycin is an effective method for the treatment of lymphatic malformations in oral maxillofacial regions. The mass can be shrank markedly to improve facial symmetry.
The First Hospital of Baoding, Department of Oral and Maxillofacial Surgery, Baoding 071000, China.
Wei
W
Zhang
Quan-Feng
QF
Luo
Ling
L
Zhang
Tong-Xuan
TX
Zhang
Xiang-Li
XL
He
D000293:Adolescent; D001761:Bleomycin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D044148:Lymphatic Abnormalities / Q000188:drug therapy*; D008297:Male; D019767:Maxillofacial Abnormalities / Q000188:drug therapy*; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000627:therapeutic use*; D055815:Young Adult
D001761:Bleomycin; C025703:bleomycetin; D014222:Triamcinolone Acetonide