Prevalence of hepatitis C virus infection among hemodialysis patients in a single center in Yemen.
To evaluate the prevalence of anti-hepatitis C virus (HCV) among the hemodialysis patients and to identify the risk factors of infection in relation to age, sex, blood transfusions, duration of dialysis and primary cause of end stage-kidney disease. We studied 51 patients who were on chronic hemodialysis (HD) at the Al-Gamhourea Teaching Hospital, Aden, Yemen, during Jan-Dec 2007. All the patients were tested for anti-HCV antibody, and we used 100 healthy blood donors as controls. The anti-HCV antibody prevalence rate among the HD patients was found to be significantly higher than that in the control group (62.7% and 0.8%, respectively). The prevalence rate of anti-HCV antibody was higher among men (64%) than that in women (35%). The anti-HCV antibody-positive patients were significantly older than the anti-HCV-antibody-negative patients (66.5 ± 14.4 years versus 57.5 ± 15.4 years; P = 0.01). Diabetic nephropathy was a more frequent cause of end-stage renal disease among the anti-HCV antibody-positive patients (30%) than among the anti-HCV antibody-negative patients (19%). Among the anti-HCV-positive patients, 80% had received a blood transfusion, which was significantly higher than the 20% rate among the anti-HCV antibody-negative patients (P < 0.001).
Faculty of Medicine and Health Sciences, Aden University, Aden, Yemen. sbinsilm@hotmail.com
Salem Bin
SB
Selm
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003928:Diabetic Nephropathies / Q000453:epidemiology; D005260:Female; D006526:Hepatitis C / Q000175:diagnosis / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D006435:Renal Dialysis; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D065227:Transfusion Reaction; D015006:Yemen / Q000453:epidemiology
D015415:Biomarkers; D018937:Hepatitis C Antibodies