[Primary metastatic well-differentiated neuroendocrine tumor arising in a tailgut cyst].
Tailgut cysts are unusual benign cystic retrorectal malformations arising from persistent remnants of the postanal gut. Malignant transformation within this dysontogenetic lesion is very uncommon. We report the rare occurrence of a neuroendocrine tumor arising in a tailgut cyst with primary liver and lymph node metastases in a 55-year-old woman. The neuroendocrine differentiation of the tumor determines the therapeutic approach and prognosis.
Institut für Pathologie, HELIOS Kliniken Schwerin, Wismarsche Str. 393-397, 19049, Schwerin, Deutschland. michael.woehlke@helios-kliniken.de
M
M
Wöhlke
J
J
Sauer
K
K
Dommisch
S
S
Görling
A
A
Valdix
R
R
Hinze
D014408:Biomarkers, Tumor / Q000032:analysis; D002455:Cell Division / Q000502:physiology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003560:Cysts / Q000151:congenital* / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006222:Hamartoma / Q000151:congenital* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D053552:Keratin-7 / Q000032:analysis; D019394:Ki-67 Antigen / Q000032:analysis; D008113:Liver Neoplasms / Q000473:pathology* / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D012002:Rectal Diseases / Q000151:congenital* / Q000473:pathology* / Q000601:surgery; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery; D012445:Sacrococcygeal Region / Q000473:pathology* / Q000601:surgery; D016708:Synaptophysin / Q000032:analysis
D014408:Biomarkers, Tumor; D053552:Keratin-7; D019394:Ki-67 Antigen; D016708:Synaptophysin