Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats.
We investigated the weight-gain suppressive effect of Lactobacillus gasseri BNR17 isolated from human breast milk. Rats were fed a high-carbohydrate diet and administered BNR17 (BNR17 group) twice daily for twelve weeks. Changes were observed in body weight and white adipose tissue mass. The percent increase in body weight (P=0.0331) and fat pad mass (P<0.01) was significantly lower in the BNR17 group, and the FER was moderately lower (P=0.0769). These data suggest that BNR17 can prevent diet-induced overweight and may become an alternative method for treating weight problems and obesity.
R&D Center, BIONEER Co, Daejeon 306-220, Republic of Korea.
Ji-Hee
JH
Kang
Sung-Il
SI
Yun
Han-Oh
HO
Park
D000273:Adipose Tissue / Q000473:pathology*; D000818:Animals; D004035:Diet Therapy / Q000379:methods*; D006801:Humans; D007778:Lactobacillus / Q000254:growth & development* / Q000302:isolation & purification; D008895:Milk, Human / Q000382:microbiology; D050177:Overweight / Q000628:therapy*; D019936:Probiotics / Q000008:administration & dosage*; D051381:Rats; D016896:Treatment Outcome