Hip arthroplasty in patients with Gaucher disease.
Patients with Gaucher disease suffering from the consequences of femoral head osteonecrosis deserve a treatment modality that will eliminate pain, preserve ambulation and hopefully will endure long enough to allow satisfactory daily life. Total hip arthroplasty fulfills these 3 objectives. The rate of complications during anesthesia and during surgical procedure is comparable to otherwise healthy population if the Gaucher patients are carefully evaluated pre-surgery and prepared by a medical team familiar with all aspects of the disease. With prompt preparation, meticulous procedure, and careful post-operative care, patients with Gaucher disease may benefit from long-lasting hip prostheses. It is to be hoped that newer types of implants would allow longer revision-free periods even in this young patient population who have developed avascular necrosis, and a greater hope for patients with Gaucher disease would be that early administration of bone-specific therapies may prevent osteonecrosis.
Department of Orthopedic Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Ehud
E
Lebel
Alexander
A
Ioscovich
Menachem
M
Itzchaki
Ari
A
Zimran
Deborah
D
Elstein
D019644:Arthroplasty, Replacement, Hip; D001847:Bone Diseases / Q000209:etiology* / Q000601:surgery*; D005776:Gaucher Disease / Q000150:complications* / Q000601:surgery*; D006801:Humans; D011182:Postoperative Care