Structural organization of the Golgi apparatus.
The Golgi apparatus is a universal feature of eukaryotes, carrying out the key functions of processing, sorting and trafficking of newly synthesized membrane and secretory proteins. The Golgi apparatus has a clearly defined structure, comprising stacks of flattened cisternal membranes that in vertebrates are connected to form a ribbon. How this structure is maintained and how it relates to the functions of the Golgi apparatus has long been an area of interest. In this review I describe recent progress in the identification and characterization of the molecular machinery that together help generate the characteristic organization of this organelle.
Faculty of Life Sciences, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK. martin.lowe@manchester.ac.uk
Martin
M
Lowe
D000199:Actins / Q000378:metabolism; D000818:Animals; D006056:Golgi Apparatus / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D008840:Microfilament Proteins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism; D008954:Models, Biological
D000199:Actins; D008840:Microfilament Proteins