Highly chemoselective palladium-catalyzed cross-trimerization between alkyne and alkenes leading to 1,3,5-trienes or 1,2,4,5-tetrasubstituted benzenes with dioxygen.
A palladium-catalyzed 1:2 linear/cyclic cross-trimerization of alkyne with alkenes using molecular oxygen as the sole oxidant has been reported for the first time. A series of 1,3,5-trienes and 1,2,4,5-tetrasubstituted benzenes are obtained with high chemoselectivity respectively and mechanisms of these reactions are proposed based on some controlled examination.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, People's Republic of China.
Peng
P
Zhou
Liangbin
L
Huang
Huanfeng
H
Jiang
Azhong
A
Wang
Xianwei
X
Li