[When is severe haemophilia A diagnosed in children and when do they start to bleed? Re-evalution after 10 years of experience].
Based on a previous investigation, the aim of this study was to re-evaluate when children with severe haemophilia A (FVIII:C <1%) are diagnosed and when they start to bleed. Data from previously untreated patients (n = 20) were collected.


RESULTS
95% of the patients experienced their first bleeding episode at the age of less than one year. On average, the first non-joint bleed occurred at the age of 0.85 years, whereas the first joint bleed developed approximately a half year later at the age of 1.49 years. Compared to the previous investigation children were diagnosed earlier, i.e. at the age of 3.7 month on average.
Institut für Thrombophilie und Hämostaseologie, Praxis Dr. med. Hartmut Pollmann, Loerstraße 19, 48143 Münster. ith@haemophilie-zentrum.de
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Pollmann
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Siegmund
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Richter
D017668:Age of Onset; D002648:Child; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000150:complications / Q000175:diagnosis*; D006470:Hemorrhage / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007223:Infant; D012720:Severity of Illness Index