Antimicrobial resistance in Hispanic patients hospitalized in San Antonio, TX with community-acquired pneumonia.
Limited information is available on the antimicrobial resistance of patients with community-acquired pneumonia (CAP) depending on their ethnicity. Our aim was to compare the clinical characteristics, etiology, and microbiological resistance of Hispanic versus non-Hispanic white patients. A retrospective cohort of 601 patients with a diagnosis of CAP included 288 non-Hispanic whites and 313 Hispanics. Penicillin-resistant Streptococcus pneumoniae was more common among Hispanic patients (21.7% vs 0%; P=0.03) but there were no significant differences in macrolide-resistant S pneumoniae, drug-resistant S pneumoniae, or potential or actual multidrug-resistant pathogens (eg, drug-resistant S pneumoniae, methicillin-resistant Staphylococcus aureus, Pseudomonas spp., and Acinetobacter spp.). There were no differences among groups in length of hospital stay, intensive care unit (ICU) admission, or 30-day mortality. This study suggests that Hispanic patients with CAP have a higher rate of penicillin-resistant S pneumoniae, but no differences in antimicrobial resistance, 30-day mortality, ICU admission, or length of stay when compared with non-Hispanic white patients.
Veterans Evidence-Based Research, Dissemination, and Implementation Center (VERDICT), San Antonio, TX 78229, USA. restrepom@uthscsa.edu
Marcos I
MI
Restrepo
Maria I
MI
Velez
Gloria
G
Serna
Antonio
A
Anzueto
Eric M
EM
Mortensen
D000368:Aged; D016009:Chi-Square Distribution; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000208:ethnology* / Q000382:microbiology; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010403:Penicillin Resistance; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis / Q000208:ethnology* / Q000382:microbiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013296:Streptococcus pneumoniae; D013781:Texas / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data