Comparison of corneal thickness and haze in DSAEK and penetrating keratoplasty.
OBJECTIVE
To compare corneal thickness and haze in Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK).


METHODS
This study included 30 consecutive patients undergoing DSAEK (18 patients) and PK (12 patients). Central corneal thickness and corneal haze were analyzed longitudinally by Pentacam (Oculus, Wetzlar, Germany) at 2 weeks, 1 month, and 3 months after grafting.


RESULTS
The mean age of patients in the DSAEK group was 71.42 ± 9.91 years (range, 55-85 years) and in the PK group was 60.58 ± 16.58 years (range, 31-81 years). Two weeks, 1 month, and 3 months after surgery, the cornea was significantly thicker in the DSAEK group compared with the PK group (P < 0.01). Two weeks, 1 month, and 3 months after the operation, the cornea had significantly more haze in the DSAEK group compared with the PK group (P < 0.05). Haze in the DSAEK group was mainly observed in the subepithelial stroma.


CONCLUSIONS
DSAEK grafts were significantly thicker with increased haze for up to 3 months after surgery. Scheimpflug system is available for quantifying not only corneal thickness but also corneal haze after various keratoplasty procedures.
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Yuichi
Y
Uchino
Shigeto
S
Shimmura
Takefumi
T
Yamaguchi
Tetsuya
T
Kawakita
Yukihiro
Y
Matsumoto
Kazuno
K
Negishi
Kazuo
K
Tsubota
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001837:Body Weights and Measures; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000601:surgery; D003318:Corneal Opacity / Q000175:diagnosis* / Q000209:etiology; D057111:Descemet Stripping Endothelial Keratoplasty; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D010781:Photography; D011183:Postoperative Complications; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology