[Histologic analysis and long-term effect of acellular dermal matrix combined with autologous thin split-thickness skin graft].
OBJECTIVE
To evaluate the long-term therapeutic effect and histologic result of ADM combined with autologous thin split-thickness skin graft.


METHODS
23 patients were treated with acellular dermal matrix (ADM) combined with autologous thin split-thickness skin graft. The patients were followed up at 3, 6, 12, and 18 months after operation. The histological analysis was also performed.


RESULTS
3, 6, 12, 18 months after operation, the composite skin grafts became smooth with no hypertrophic scar and hyperpigmentation. It was soft and elastic. The joints could move randomly. The histologic study showed the composite skin graft had a similar appearance as the normal skin.


CONCLUSIONS
As for the treatment of wound, the composite skin graft with ADM is smooth and soft with good elasticity after transplantation, but it has no perspiration.
Department of Burn and Plastic Surgery, Shandong Province Hospital, Jinan 250012, China.
Li-Hui
LH
Han
Ren-Rong
RR
Lü
Ran
R
Huo
Dong-Liang
DL
Yuan
Xuan
X
Guo
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D020405:Dermis / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000379:methods*; D017768:Skin, Artificial; D014182:Transplantation, Autologous; D055815:Young Adult