[Regulatory B cells and their role in maintaining peripheral tolerance].
The immune system is regulated by a variety of mechanisms that prevent overwhelming immune responses and a break in tolerance. There have been indications for some time that populations of B cells are also a part of this network and able to exert regulatory functions. Here we summarize current knowledge on this previously unrecognized B cell function and their potential role in protection against autoimmunity.
Sektion Rheumatologie, Medizinische Klinik V, Universität Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg. Theresa.Tretter@med.uni-heidelberg.de
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D000818:Animals; D015551:Autoimmunity / Q000276:immunology*; D016175:B-Lymphocyte Subsets / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D018448:Models, Immunological