Lung function after total intravenous anaesthesia or balanced anaesthesia with sevoflurane.
BACKGROUND
We investigated the effects of total i.v. anaesthesia (TIVA) and balanced anaesthesia (BAL) with sevoflurane on postoperative lung function in patients undergoing surgery in the prone position.


METHODS
Sixty patients, aged 21-60 yr, undergoing elective lumbar disc surgery in the prone position were randomly allocated to undergo TIVA (propofol-remifentanil) or BAL (fentanyl-nitrous oxide-sevoflurane). Forced vital capacity (FVC), forced expiratory volume in 1 s, mid-expiratory flow (MEF 25-75), and peak expiratory flow were measured before and after general anaesthesia.


RESULTS
Both groups were similar with respect to patient characteristic data and preoperative lung function parameters. Irrespective of the type of anaesthesia administered, lung function parameters decreased after operation, with the decrease in FVC being greater after TIVA than after BAL with sevoflurane.


CONCLUSIONS
In patients emerging from general anaesthesia, postoperative reduction in FVC is greater after TIVA than after BAL with sevoflurane.
Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria.
W
W
Tiefenthaler
D
D
Pehboeck
E
E
Hammerle
P
P
Kavakebi
A
A
Benzer
D000328:Adult; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D008738:Methyl Ethers / Q000009:adverse effects*; D008875:Middle Aged; D010366:Peak Expiratory Flow Rate / Q000187:drug effects; D011183:Postoperative Complications; D012120:Respiration Disorders / Q000139:chemically induced* / Q000503:physiopathology; D000077149:Sevoflurane; D013147:Spirometry / Q000379:methods; D014797:Vital Capacity / Q000187:drug effects; D055815:Young Adult
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane