[A case of fat embolism syndrome associated with pathological femoral fracture caused by metastatic adenocarcinoma of the lung].
A 76-year-old woman with multiple bone metastases from lung adenocarcinoma was admitted due to a pathological femoral fracture. On the night after admission, her consciousness deteriorated rapidly and she developed progressive respiratory failure. Computed tomography of the chest revealed diffuse ground glass opacities in both lungs, and magnetic resonance imaging of the brain showed multiple acute infarctions. Her condition improved after several days of supportive treatment with oxygen, corticosteroids and diuretics. Fat embolism syndrome should be considered as a differential diagnosis if consciousness disturbance and respiratory failure occur in patients with metastatic bone carcinoma and pathological long bone fractures.
Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine.
Takashi
T
Sato
Kenzo
K
Soejima
Sohei
S
Nakayama
Ryosuke
R
Satomi
Koichi
K
Sayama
Koichiro
K
Asano
D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D004620:Embolism, Fat / Q000209:etiology*; D005260:Female; D005264:Femoral Fractures / Q000209:etiology*; D005598:Fractures, Spontaneous / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*