Ultra-wide-field and autofluorescence imaging of choroidal dystrophies.
The authors retrospectively identified 2 cases of gyrate atrophy, 3 cases of choroideremia, and 1 case of the carrier state of choroideremia who underwent ultra-wide-field fundus photography and fluorescein angiography. The findings were studied and compared to standard fundus photography and fluorescein angiography. Gyrate atrophy demonstrated a diffuse confluent extent of chorioretinal atrophy extending from the anterior to the posterior pole to the periphery. Choroideremia demonstrated a patchy irregular pattern of chorioretinal atrophy extending from the posterior pole to the periphery. Peripheral reticular degeneration without chorioretinal atrophy was appreciated in the carrier state. Ultra-wide-field imaging of these choroidal dystrophies demonstrated distinctive patterns that may aid in their identification and diagnosis.
Jules Stein Eye Institute, UCLA Geffen School of Medicine, Los Angeles, California, USA.
Alex
A
Yuan
Andrew
A
Kaines
Atul
A
Jain
Shantan
S
Reddy
Steven D
SD
Schwartz
David
D
Sarraf
D000293:Adolescent; D000328:Adult; D002829:Choroid / Q000473:pathology; D015862:Choroid Diseases / Q000175:diagnosis*; D015794:Choroideremia / Q000175:diagnosis; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005453:Fluorescence; D005654:Fundus Oculi; D015799:Gyrate Atrophy / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology; D012189:Retrospective Studies