Early complications after nipple-sparing mastectomy and immediate breast reconstruction with silicone prosthesis: results of 214 procedures.
OBJECTIVE
breast reconstruction with silicone prosthesis following nipple-sparing mastectomy has become widely accepted as a reconstruction option in women requiring mastectomy for cancer. The purpose of this study was to evaluate the incidence and some factors influencing early local complications in patients undergoing NSM with immediate implant reconstruction.


METHODS
prospective study was performed on a consecutive series of 214 breast reconstructions in 205 patients. All complications during the six weeks after surgery were recorded. 42 prostheses were implanted after neoadjuvant chemotherapy, 27 patients previously had radiotherapy due to breast conserving surgery and in all other cases surgery was the pri-mary treatment for cancer.


RESULTS
the overall six-week complication rate was 16% (35) and included: major skin flap necrosis (4%, 9 procedures), minor skin necrosis (3%, 7), major infection (2%, 5), minor infection (3%, 7), prolonged seroma formation (3%, 6), haematoma (1%, 2) and epidermolysis (1%, 2). In 6% (12) reconstruction procedures explantation of prosthesis was done. Neoadjuvant chemo-therapy and radiotherapy were not associated with higher rate of complications.


CONCLUSIONS
nipple-sparing mastectomy with immediate implant reconstruction has acceptable morbidity rate in the hand of experienced oncoplastic surgeon and therefore should be considered as treatment option to women requiring mastectomy.
Oncology Institute of Vojvodina, Department of Surgical Oncology Institutski, Sremska Kamenica, Novi Sad, Serbia. zoran.r@eunet.rs
Z
Z
Radovanovic
D
D
Radovanovic
A
A
Golubovic
T
T
Ivkovic-Kapicl
B
B
Bokorov
A
A
Mandic
D000328:Adult; D000368:Aged; D019928:Breast Implantation; D018427:Breast Implants; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000009:adverse effects* / Q000379:methods; D008875:Middle Aged; D009336:Necrosis; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D018714:Radiotherapy, Adjuvant; D049291:Seroma / Q000453:epidemiology; D012826:Silicone Elastomers; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
D012826:Silicone Elastomers