A cross-sectional cohort study of infertile women awaiting oocyte donation: the emotional, sexual, and quality-of-life impact.
OBJECTIVE
To examine the emotional, sexual, physical, and quality-of-life (QOL) impact on infertile women awaiting oocyte donation.


METHODS
Cross-sectional cohort study.


METHODS
Cancer center and reproductive medicine center.


METHODS
Fifty infertile women awaiting oocyte donation, enrolled from October 2006 to February 2009.


METHODS
Woman awaiting oocyte donation completed a one-time survey of empirical measures and exploratory items.


METHODS
Reproductive concerns, depression, sexual function, distress, menopausal symptoms, physical and mental health, and relationship satisfaction.


RESULTS
Of the participants, 33% were clinically depressed (Center for Epidemiologic Studies Depression Scale), and 59% had high levels of distress (Impact of Events Scale). The cohort's mean Female Sexual Function Index score (24.09) was below the cutoff value (26.55), indicating sexual dysfunction. Relationship satisfaction (Abbreviated Dyadic Adjustment Scale) scores were comparable to the population norm. Patients had good physical QOL but below average mental QOL (Medical Outcomes SF-12 Health Survey). Sixty-four percent were concerned about long-term effects of treatment, although 94% were grateful for reproductive assistance options and described parenthood as providing enrichment, happiness, and meaning to their lives.


CONCLUSIONS
Infertility can negatively impact sexual function, QOL, and emotional well-being. Quantitative empirical measures and qualitative data have shown that these women experienced and recognized the emotional toll of reproductive assistance. Despite concerns about the long-term effects of treatment, participants were grateful for this third-party parenting option.
Department of Psychiatry, Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA. gynbreast@mskcc.org
Jeanne
J
Carter
Linda
L
Applegarth
Laura
L
Josephs
Elizabeth
E
Grill
Raymond E
RE
Baser
Zev
Z
Rosenwaks
D000328:Adult; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000523:psychology* / Q000628:therapy*; D008593:Menopause / Q000502:physiology / Q000523:psychology; D008875:Middle Aged; D018587:Oocyte Donation / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology; D012725:Sexual Behavior / Q000502:physiology / Q000523:psychology*; D012944:Social Support; D014850:Waiting Lists; D055815:Young Adult