Effect of outer mandibular cortex osteotomy on local morphology and biomechanics in young miniature pigs.
OBJECTIVE
The purpose of this study was to research the effect of outer mandibular cortex osteotomy on local morphology and biomechanics in young miniature pigs.


METHODS
Eight 3-month-old miniature pigs were used as experimental animals to establish an animal model for removing the outer cortex of the mandibular body, and the changes in local morphology, fine structure, and biomechanics of the mandible after the operation were evaluated.


RESULTS
The thickness of the operated side decreased to a greater extent than that of the control side. Further, local histologic structure and biomechanics characteristics could be recovered under stress conditions and were close to those of the normal side after the operation. However, some animals (37.5%) exhibited mandible deviation after operation.


CONCLUSIONS
Under normal conditions, mandibular outer cortex osteotomy should not be performed in the case of children.
Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Science, Peking Union Medical College, No 33, Ba-Da-Chu Road, Shi Jing Shan District, Beijing 100144, China.
Wei
W
Liu
Zhi-yong
ZY
Zhang
Xiao-jun
XJ
Tang
Ji-chang
JC
Wang
Lai
L
Gui
D000367:Age Factors; D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density; D016723:Bone Remodeling; D000075202:Contraindications; D003799:Dental Stress Analysis; D005146:Facial Asymmetry / Q000209:etiology; D005260:Female; D008297:Male; D008334:Mandible / Q000473:pathology* / Q000601:surgery* / Q000648:ultrastructure; D023421:Models, Animal; D019647:Oral Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D010027:Osteotomy / Q000009:adverse effects / Q000379:methods*; D013552:Swine; D013556:Swine, Miniature