JBIR-66, a new metabolite isolated from tunicate-derived Saccharopolyspora sp. SS081219JE-28.
In the course of our chemical screening program for new secondary metabolites, we isolated a new compound JBIR-66 (1) from the culture broth of the tunicate-derived actinomycete, Saccharopolyspora sp. SS081219JE-28. The structure of 1 was determined to be (3Z,6E,8E)-N-(4-acetamido-3-hydroxybutyl)-2-hydroxy-4,8-dimethylundeca-3,6,8-trienamide on the basis of extensive NMR and MS spectroscopic data.
Biomedicinal Information Research Center (BIRC), Japan Biological Informatics Consortium (JBIC), Tokyo, Japan. motoki-takagi@aist.go.jp
Motoki
M
Takagi
Keiichiro
K
Motohashi
Miho
M
Izumikawa
Shams Tabrez
ST
Khan
Ji-Hwan
JH
Hwang
Kazuo
K
Shin-Ya
D000577:Amides / Q000737:chemistry; D000818:Animals; D003470:Culture Media / Q000737:chemistry; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D016930:Saccharopolyspora / Q000378:metabolism*; D014561:Urochordata
D000577:Amides; D003470:Culture Media