Use of recombinant activated factor VII for reduction of perioperative blood loss during elective surgical correction of spine deformity in a Jehovah's Witness. Case report.
Planned surgical procedures at patients who refuse allogenic blood transfusion because of religious convictions are important problem, not only medical but also ethical and juristical. At the study authors report the successful use of activated recombinant factor VII (rFVIIa) for the reduction of perioperative blood loss in four years old child - Jehovah's Witness, who had planned Torode kyphectomy. Applied perioperative management together with preparing to surgery with erythropoietin allowed for reduction of blood loss and avoiding of blood transfusion. Authors state, that appropriate perioperative proceeding makes a possibility of safe surgical procedures also at patients who refuse the transfusion.
Katedra i Klinika Ortopedii i Rehabilitacji w Zakopanem, Uniwersytet Jagielloński, Collegium Medicum, Zakopane, Polska. katkacka@tlen.pl
Katarzyna
K
Kącka
Wojciech
W
Kącki
Joanna
J
Merak
Adam
A
Błęka
D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002648:Child; D004921:Erythropoietin / Q000627:therapeutic use*; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006401:Hematologic Agents / Q000627:therapeutic use*; D006801:Humans; D033221:Jehovah's Witnesses; D007738:Kyphosis / Q000601:surgery*; D011994:Recombinant Proteins / Q000627:therapeutic use; D013131:Spine / Q000601:surgery
D006401:Hematologic Agents; D011994:Recombinant Proteins; D004921:Erythropoietin; C103587:recombinant FVIIa; D015942:Factor VIIa