Recurrent posterior fossa anaplastic ependymoma with prominent chondroid metaplasia: a case report and review of literature.
We report an unusual case of a recurrent fourth ventricular anaplastic ependymoma with prominent chondroid metaplasia in a 16-year-old male. On initial presentation, the patient had a WHO Grade II tumor. However, at recurrence 1 year later, the tumor progressed to WHO Grade III tumor with more cellularity, necrosis and brisk mitotic activity. Chondroid metaplasia was present in both the initial and recurrent tumors.
Department of Pathology and Transfusion Medicine, Sri Sathya Sai Institute of Higher Medical sciences, Bangalore, Karnataka, India. nandita.g@rediffmail.com
Nandita
N
Ghosal
Ganesh
G
Murthy
Ravi
R
Dadlani
Alangar Sathya
AS
Hegde
Devendra
D
Singh
D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D020219:Chondrogenesis; D003388:Cranial Fossa, Posterior / Q000473:pathology*; D004806:Ependymoma / Q000175:diagnosis* / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006257:Head / Q000000981:diagnostic imaging; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008679:Metaplasia / Q000473:pathology*; D018396:Mucin-1 / Q000032:analysis; D011859:Radiography; D012008:Recurrence; D012720:Severity of Illness Index
D005904:Glial Fibrillary Acidic Protein; D018396:Mucin-1