Paraneoplastic myopathy as a very rare manifestation of acute lymphoblastic leukemia.
We present a 9-year-old girl who developed acute muscular weakness of proximal muscles of the upper and lower limbs. Investigations revealed a common acute lymphoblastic leukemia. The neuromuscular symptoms are classified as a paraneoplastic neurological syndrome (PNS). Under chemotherapy according to ALL-BFM-2000 protocol symptoms resolved within 4 weeks. This case presents a rare manifestation of acute lymphoblastic manifestation.
Abteilung für Kinder- und Jugendmedizin, Gemeinschaftskrankenhaus, Gerhard-Kienle Weg 4, Herdecke, Germany. gkameda@gemeinschaftskrankenhaus.de
G
G
Kameda
S
S
Vieker
C
C
Duck
F
F
Blaes
A
A
Längler
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018908:Muscle Weakness / Q000175:diagnosis / Q000188:drug therapy; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000188:drug therapy; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy