Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst.
In this study, we developed an efficient and selective iron-based catalyst system for the synthesis of ketones from secondary alcohols and carboxylic acids from primary alcohol. In situ generated iron catalyst of thymine-1-acetate (THA) and FeCl(3) under solvent-free condition exhibits high activity. As an example, 1-octanol and 2-octanol were oxidized to 1-octanoic acid and 2-octanone with 89% and 98% yields respectively.
Department of Chemistry, Laboratory of Inorganic Chemistry, P.O. Box 55, FIN-00014, University of Helsinki, Finland.
Afnan
A
Al-Hunaiti
Teemu
T
Niemi
Ahlam
A
Sibaouih
Petri
P
Pihko
Markku
M
Leskelä
Timo
T
Repo