miSolRNA: A tomato micro RNA relational database.
BACKGROUND
The economic importance of Solanaceae plant species is well documented and tomato has become a model for functional genomics studies. In plants, important processes are regulated by microRNAs (miRNA).


METHODS
We describe here a data base integrating genetic map positions of miRNA-targeted genes, their expression profiles and their relations with quantitative fruit metabolic loci and yield associated traits. miSolRNA provides a metadata source to facilitate the construction of hypothesis aimed at defining physiological modes of action of regulatory process underlying the metabolism of the tomato fruit.


CONCLUSIONS
The MiSolRNA database allows the simple extraction of metadata for the proposal of new hypothesis concerning possible roles of miRNAs in the regulation of tomato fruit metabolism. It permits i) to map miRNAs and their predicted target sites both on expressed (SGN-UNIGENES) and newly annotated sequences (BAC sequences released), ii) to co-locate any predicted miRNA-target interaction with metabolic QTL found in tomato fruits, iii) to retrieve expression data of target genes in tomato fruit along their developmental period and iv) to design further experiments for unresolved questions in complex trait biology based on the use of genetic materials that have been proven to be a useful tools for map-based cloning experiments in Solanaceae plant species.
Instituto de Biotecnología, Instituto Nacional de Tecnología Agropecuaria (Partner group of Institution 5), Castelar, Argentina.
Ariel A
AA
Bazzini
Ramón
R
Asís
Virginia
V
González
Sebastián
S
Bassi
Mariana
M
Conte
Marcelo
M
Soria
Alisdair R
AR
Fernie
Sebastián
S
Asurmendi
Fernando
F
Carrari
D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D019295:Computational Biology / Q000379:methods; D030541:Databases, Genetic; D005638:Fruit / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D016247:Information Storage and Retrieval; D018551:Solanum lycopersicum / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism
D035683:MicroRNAs