[Therapeutic effect and side effect of treatment on hyperthyroid exophthalmos with the combination of acupuncture and medication].
OBJECTIVE
To compare the therapeutic effect and side effect of the treatments on hyperthyroid exophthalmos with the combination of acupuncture and medication and with medication only.


METHODS
Fifty-two cases were randomly divided into an acupuncture and medication group (27 cases) and a medication group (25 cases). Acupuncture in combination of oral taking of Thiamazole and Euthyrox were adopted for the acupuncture and medication group. And acupoints such as Jingming (BL 1), Chengqi (ST 1) and Sizhukong (TE 23) etc. were selected. Western medication for oral taking was applied as the only treatment for the medication group. Objective eye syndrome marks, side effects and accidents were compared between two groups before and after treatment.


RESULTS
The improvement of the objective marks of eye syndrome in the acupuncture and medication group was better than that in the medication group (P < 0.01). There were 4 cases with hypoleucocytosis, 3 cases with rash and 3 cases with aggravated symptom of exophthalmos in the medication group during the treatment, while no case with side effects was observed in the acupuncture and medication group. However, 8 cases were found with hemorrhage and 8 with hematoma in the acupuncture and medication group.


CONCLUSIONS
Treatment with the combination of acupuncture and medication may not only enhance the therapeutic effect, but also reduce the side effects.
College of Acupuncture and Massage, Shanghai University of TCM, Shanghai 201203, China. Department of Chinese Medicine, Shanghai Changhai Hospital.
Yong
Y
Xia
Shi
S
Shu
Yi
Y
Li
Shi-Min
SM
Liu
Jin-Sen
JS
He
D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000009:adverse effects; D000328:Adult; D003131:Combined Modality Therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D005094:Exophthalmos; D005260:Female; D049970:Graves Ophthalmopathy / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D008297:Male; D008713:Methimazole / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D013974:Thyroxine / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
D008713:Methimazole; D013974:Thyroxine