[Physical activity as a preventive measure for coronary artery disease].
Cardiovascular benefits of regular physical activity are well described and validated. Coronary disease, both in primary and secondary prevention, is markedly concerned. Physical activity corrects most of the cardiovascular risk factors. Moreover, it has also a direct impact on the atherosclerosis progression. It seems that physical activity limits the chronic inflammatory state and oxidative stress level by its modulation on the PGC-1 alpha regulation. Unfortunately, despite this high level of proof, the physical activity prescription level is actually low.
Inserm U, hôpital Pontchaillou, université Rennes, France. francois.carre@chu-rennes.fr
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D003324:Coronary Artery Disease / Q000517:prevention & control*; D006801:Humans; D009043:Motor Activity