Orthokeratinized odontogenic cyst: a systematic review.
OBJECTIVE
The aims of the review were to evaluate the principal clinical and conventional radiographic features of orthokeratinized odontogenic cyst (OOC) by systematic review (SR), and to compare the frequency of OOC between four global groups.


METHODS
The databases searched were the PubMed interface of MEDLINE and LILACS. Only those reports of OOCs that occurred in a consecutive series of OOCs in the reporting authors' caseload were considered.


RESULTS
37 reports on 36 case series were included in the SR. OOC affected males twice as frequently and the mandible almost 2.5 times as frequently. Although the mean age at first presentation was 35 years, the largest proportion of cases first presented in the third decade for the Western, East Asian and Latin American global groups. Seven reports included details of at least one clinical finding. 11 reported case series included at least 1 radiological feature. All OOCs were radiolucent, 93% were unilocular and 68% were associated with unerupted teeth. 28% of the reported case series included follow up. 4% of OCC recurred and all of these were in the Western global group.


CONCLUSIONS
Although one feature of OOCs is that they are unlikely to recur, some do. Not only is there a lack of long-term follow up of large series with long-term outcomes of OOC, but there is a paucity of clinical and radiological details of OOC at initial presentation.
Division of Oral & Maxillofacial Radiology, Faculty of Dentistry, UBC, 2199 Wesbrook Mall, Vancouver V6T 1Z3, BC, Canada. dmacdon@interchange.ubc.ca
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Macdonald-Jankowski
D017954:Africa South of the Sahara / Q000453:epidemiology; D005060:Europe / Q000453:epidemiology; D005202:Asia, Eastern / Q000453:epidemiology; D006801:Humans; D007571:Jaw Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D007633:Keratins; D007843:Latin America / Q000453:epidemiology; D009656:North America / Q000453:epidemiology; D009807:Odontogenic Cysts / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D011859:Radiography; D012744:Sex Ratio
D007633:Keratins