Influence of the absorption behavior of sunscreens in the short-wavelength UV range (UVB) and the long-wavelength UV range (UVA) on the relation of the UVB absorption to sun protection factor.
The absorption of filter substances in sunscreens, reducing the incident ultraviolet (UV) radiation, is the basis for the protecting ability of such formulations. The erythema-correlated sun protection factor (SPF), depending mainly on the intensity of the UVB radiation, is the common value to quantify the efficacy of the formulations avoiding sunburn. An ex vivo method combining tape stripping and optical spectroscopy is applied to measure the absorption of sunscreens in the entire UV spectral range. The obtained relations between the short-wavelength UV (UVB) absorption and the SPF confirm a clear influence of the long-wavelength UV (UVA) absorption on the SPF values. The data reflect the historical development of the relation of the concentration of UVB and UVA filters in sunscreens and points to the influence of additional ingredients, e.g., antioxidants and cell-protecting agents on the efficacy of the products.
Charité-Universitätsmedizin Berlin, Department of Dermatology and Allergology, Center of Experimental and Applied Cutaneous Physiology, Charitéplatz 1, 10117 Berlin, Germany.
Hans-Juergen
HJ
Weigmann
Sabine
S
Schanzer
Christina
C
Antoniou
Wolfram
W
Sterry
Juergen
J
Lademann
D000328:Adult; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000187:drug effects* / Q000293:injuries / Q000378:metabolism / Q000528:radiation effects*; D013054:Spectrophotometry, Atomic; D013471:Sunburn / Q000517:prevention & control; D013473:Sunscreening Agents / Q000494:pharmacology*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D055815:Young Adult
D013473:Sunscreening Agents