Small coronary vessel angioplasty: outcomes and technical considerations.
Small vessel (<3 mm) coronary artery disease is common and has been identified as independent predictor of restenosis after percutaneous coronary intervention. It remains controversial whether bare-metal stent (BMS) implantation in small vessels has an advantage over balloon angioplasty in terms of angiographic and clinical outcomes. Introduction of drug-eluting stent (DES) has resulted in significant reduction in restenosis and the need for repeat revascularization. Several DESs have been introduced resulting in varying reduction in outcomes as compared with BMS. However, their impact on outcomes in small vessels is not clearly known. It is expected that DES could substantially reduce restenosis in smaller vessels. Large, randomized studies are warranted to assess the impact of different DESs on outcomes in patients with small coronary arteries.
Department of Cardiology, St George's Healthcare NHS Trust, London, UK. sudhirrathore@hotmail.com
Sudhir
S
Rathore
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000379:methods; D003324:Coronary Artery Disease / Q000601:surgery; D003331:Coronary Vessels / Q000187:drug effects / Q000601:surgery; D054855:Drug-Eluting Stents / Q000009:adverse effects; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage / Q000627:therapeutic use; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome
C489443:zotarolimus; D017239:Paclitaxel; D020123:Sirolimus