Nanostructure-initiator mass spectrometry metabolite analysis and imaging.
Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization approach that is particularly well-suited for unbiased (untargeted) metabolomics. An overview of the NIMS technology and its application in the detection of biofluid and tissue metabolites are presented. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .).
Center for Metabolomics and Mass Spectrometry, Department of Chemistry, The Scripps Research Institute.
Matthew P
MP
Greving
Gary J
GJ
Patti
Gary
G
Siuzdak
D000818:Animals; D019963:Clinical Chemistry Tests; D013058:Mass Spectrometry / Q000379:methods*; D055432:Metabolomics / Q000379:methods*; D057054:Molecular Imaging / Q000379:methods*; D049329:Nanostructures