Changes in rosacea comorbidities and treatment utilization over time.
BACKGROUND
Rosacea is a chronic skin condition that requires lifelong treatment. Given the rise in antibiotic-resistant bacteria, many physicians are re-evaluating their use of antibiotics for long-term treatment of rosacea.


OBJECTIVE
To examine trends in the treatment of rosacea and the comorbidities associated with this skin condition.


METHODS
From 2002-2006, the National Ambulatory Medical Care Survey queried drug mentions at rosacea visits and coexisting diagnoses. Prescribing patterns of dermatologists were compared to other physicians' patterns.


RESULTS
Ten million physician visits had the diagnosis of rosacea; 74 percent were associated with co-morbidities. Metronidazole, tetracyclines, azelaic acid and sodium sulfacetamide were the top medications mentioned at rosacea visits. Prescriptions increased for azelaic acid and decreased for sodium sulfacetamide. Dermatologists decreased their prescribing of systemic medications.


CONCLUSIONS
Dermatologists are reducing their use of systemic antibiotics for rosacea and turning to therapies, such as azelaic acid, that do not have potential to induce bacterial resistance.
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1071, USA.
Brad A
BA
Yentzer
Alan B
AB
Fleischer
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003879:Dermatologic Agents / Q000627:therapeutic use; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D010818:Practice Patterns, Physicians'; D012393:Rosacea / Q000150:complications / Q000188:drug therapy*; D012871:Skin Diseases / Q000150:complications
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents