Micelle to fibre biocatalytic supramolecular transformation of an aromatic peptide amphiphile.
We use a range of spectroscopic methods to provide mechanistic insight into a phosphatase-driven supramolecular transformation whereby an amphiphilic peptide building block, upon dephosphorylation, switches from a solution-phase, micellar structure to a gel-phase, chiral uni-directional nanofibre morphology.
WestCHEM, University of Strathclyde, Department of Pure and Applied Chemistry, Thomas Graham Building, 295 Cathedral Street, Glasgow, UK G1 1XL.
Jan W
JW
Sadownik
Joy
J
Leckie
Rein V
RV
Ulijn
D055162:Biocatalysis; D008823:Micelles; D057139:Nanofibers / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D010766:Phosphorylation; D011721:Pyrenes / Q000737:chemistry; D013050:Spectrometry, Fluorescence
D008823:Micelles; D010455:Peptides; D011721:Pyrenes; C030984:pyrene