[Ocular manifestations in patients affected by Morquio syndrome (MPS IV)].
OBJECTIVE
The purpose of this study was to investigate the ocular manifestations in patients suffering from Morquio syndrome.


METHODS
We reviewed the hospital records of 20 patients who underwent ophthalmological follow-up at hôpital Femme-Mère-Enfant, Bron, France, between December 2008 and February 2010.


RESULTS
This retrospective study included 20 patients: 12 males and eight females. The mean age at the beginning of the retrospective study was 23 years. The most common ocular manifestations encountered, in order of frequency, were: corneal opacification (13/20), astigmatism (12/20) and the presence of punctate cataract (6/20). Visual acuity after optical correction was over 7/10 on average. The average best corrected visual acuity was estimated to be over 0.7.


CONCLUSIONS
Although ocular complications in Morquio syndrome appeared to be associated with relatively well preserved visual acuity, ophthalmological follow-up is recommended to identify potentially curable complications such as astigmatism or lens opacities.
Service d'ophtalmologie pédiatrique, université Lyon-1, hôpital Femme-Mère-Enfant, hospices civils de Lyon, 59, boulevard Pinel, 69677 Bron cedex, France. couprie jeremy@yahoo.fr
J
J
Couprie
P
P
Denis
N
N
Guffon
N
N
Reynes
H
H
Masset
F
F
Beby
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009085:Mucopolysaccharidosis IV / Q000150:complications*; D012189:Retrospective Studies