Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity.
A lateral flow nucleic acid biosensor based on copper-dependent DNA-cleaving DNAzyme and gold nanoparticles has been developed for the visual detection of copper ions (Cu(2+)) in an aqueous solution with a detection limit of 10 nM.
South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510663, China.
Zhiyuan
Z
Fang
Jing
J
Huang
Puchang
P
Lie
Zhuo
Z
Xiao
Chuanyan
C
Ouyang
Qing
Q
Wu
Yixing
Y
Wu
Guodong
G
Liu
Lingwen
L
Zeng
D015374:Biosensing Techniques / Q000379:methods*; D003300:Copper / Q000032:analysis*; D021881:DNA, Catalytic / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry
D021881:DNA, Catalytic; D006046:Gold; D003300:Copper