Spindle epithelial tumor with thymus-like differentiation of thyroid gland: report of two cases with follow-up.
Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a rare malignant thyroid tumor showing thymic or related branchial pouch differentiation. The tumors are composed predominantly of spindle cells along with focal epithelial component and ductular formations. SETTLE occurs in young patients, with indolent growth and a tendency to develop delayed blood-borne metastases. We herein report two cases of SETTLE with a follow-up period of 64 months and 30 months, respectively.
Department of Pathology, Medical College, The Aga Khan University, Hospital, Stadium Road, Karachi, Pakistan. azizaraza2004@yahoo.com
Azizun
A
Nisa
Abrar
A
Barakzai
Khurram
K
Minhas
Naila
N
Kayani
D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology*; D002675:Child, Preschool; D005500:Follow-Up Studies; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008853:Microscopy; D009333:Neck / Q000000981:diagnostic imaging; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D013961:Thyroid Gland / Q000473:pathology*; D014057:Tomography, X-Ray Computed