Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature.
In rare cases, cutaneous larva migrans may be complicated by Löffler syndrome. This syndrome is thought to result from a type I hypersensitivity reaction related to the pulmonary larval migration phase of various parasites. It is characterized by migratory pulmonary eosinophilic infiltrates and peripheral eosinophilia, with malaise, fever, and cough. Our patient was successfully treated with ivermectin, a corticosteroid cream, and inhalation medication in an early phase, which prevented complications. We present the details of this case and review the literature.
Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
M
M
Te Booij
Emgj
E
de Jong
H J
HJ
Bovenschen
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000977:Antiparasitic Agents / Q000627:therapeutic use; D019819:Budesonide / Q000627:therapeutic use; D000069502:Budesonide, Formoterol Fumarate Drug Combination; D002990:Clobetasol / Q000627:therapeutic use; D004338:Drug Combinations; D004983:Ethanolamines / Q000627:therapeutic use; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D007815:Larva Migrans / Q000150:complications* / Q000188:drug therapy; D008297:Male; D011657:Pulmonary Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*
D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D000893:Anti-Inflammatory Agents; D000977:Antiparasitic Agents; D000069502:Budesonide, Formoterol Fumarate Drug Combination; D004338:Drug Combinations; D004983:Ethanolamines; D019819:Budesonide; D007559:Ivermectin; D002990:Clobetasol