The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose.
The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco-, β-gluco- and β-manno-chloraloses via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.
Chemistry Department, Faculty of Science, Ege University, Bornova, İzmir 35100, Turkey.
Gökhan
G
Kök
Tamer
T
Karayıldırım
Kadir
K
Ay
Emriye
E
Ay
D002698:Chloralose / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014241:Trichloroethylene / Q000737:chemistry*
D002698:Chloralose; D014241:Trichloroethylene