Vibrio vulnificus DNA load and mortality.
We determined the association between DNA load and mortality in patients with Vibrio vulnificus infection. Real-time PCR performed on sera of 27 culture-positive patients showed a significantly higher median DNA load in nonsurvivors than in survivors. Hence, real-time PCR can be used as an early prognostic factor in V. vulnificus septicemia.
Division of Infectious Disease, Department of Internal Medicine, School of Medicine, Chosun University, Gwang-ju, South Korea.
Dong-Min
DM
Kim
Sook-In
SI
Jung
Hee-Chang
HC
Jang
Chang Seop
CS
Lee
Sun Hee
SH
Lee
Na Ra
NR
Yun
Ganesh Prasad
GP
Neupane
Kyung-Hwa
KH
Park
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058491:Bacterial Load; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods; D011379:Prognosis; D018805:Sepsis / Q000382:microbiology / Q000401:mortality; D014735:Vibrio Infections / Q000382:microbiology* / Q000401:mortality*; D041261:Vibrio vulnificus / Q000235:genetics / Q000302:isolation & purification*; D055815:Young Adult
D004269:DNA, Bacterial