[PSM2 and POLR2J gene families as molecular markers of the higher primate evolution].
We have studied the molecular evolution of two gene families specific for primates: POLR2J of the transcription system and PMS2 of the MMR repair system. The appearance and improvement of the genetic structure in each of the families was shown to strongly correlate with the main stages of the higher primates biological evolution. Our results indicate that the PSM2 and POLR2J genes can serve as helpful and reliable molecular markers of anthropogenesis.
E K
EK
Shematorova
D G
DG
Shpakovskiĭ
G V
GV
Shpakovskiĭ
D000251:Adenosine Triphosphatases / Q000235:genetics*; D000818:Animals; D045643:DNA Repair Enzymes / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D019143:Evolution, Molecular; D005819:Genetic Markers; D006801:Humans; D000070976:Mismatch Repair Endonuclease PMS2; D011323:Primates / Q000235:genetics*; D012319:RNA Polymerase II / Q000235:genetics*
D004268:DNA-Binding Proteins; D005819:Genetic Markers; C502087:POLR2J protein, human; D012319:RNA Polymerase II; D000251:Adenosine Triphosphatases; C094934:PMS2 protein, human; D000070976:Mismatch Repair Endonuclease PMS2; D045643:DNA Repair Enzymes