Cardiovascular autonomic responses to whole body isotonic exercise in normotensive healthy young adult males with parental history of hypertension.
The objective of this study was to assess blood pressure and autonomic activity during rest and recovery in young adult normotensives offsprings of hypertensives. A total of 49 healthy normotensive males with BMI of 18.5-24.9 kg/m2 chosen for the study and classified into two groups based on their parental history of hypertension underwent a sub maximal cycle ergometry exercise test. ECG and heart rate were recorded at baseline, during the exercise test and during recovery period of ten minutes while blood pressure was recorded at baseline and during recovery. Spectral analysis of HRV was performed. The basal systolic blood pressure and the recovery systolic blood pressures at the 1st and 3rd minute of recovery after exercise test were significantly higher in the study group than the control group. The basal LFnu and LF/HF ratio were significantly higher while the basal HFnu was significantly lower in the study group than the control group. A difference in basal systolic blood pressure, a higher LFnu and a lower HFnu found in offspring of hypertensive parents may be an early marker of cardiovascular change in subjects with a genetic predisposition to hypertension.
Department of Physiology, St. John's Medical College, Bangalore 560 034. rajaram.sowmya@gmail.com
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R
Sowmya
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KN
Maruthy
Rani
R
Gupta
D000293:Adolescent; D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D004562:Electrocardiography; D015444:Exercise; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008297:Male; D010290:Parents; D055815:Young Adult