[Digital breast tomosynthesis : technical principles, current clinical relevance and future perspectives].
In recent years digital full field mammography has increasingly replaced conventional film mammography. High quality imaging is guaranteed by high quantum efficiency and very good contrast resolution with optimized dosing even for women with dense glandular tissue. However, digital mammography remains a projection procedure by which overlapping tissue limits the detectability of subtle alterations. Tomosynthesis is a procedure developed from digital mammography for slice examination of breasts which eliminates the effects of overlapping tissue and allows 3D imaging of breasts. A curved movement of the X-ray tube during scanning allows the acquisition of many 2D images from different angles. Subseqently, reconstruction algorithms employing a shift and add method improve the recognition of details at a defined level and at the same time eliminate smear artefacts due to overlapping structures. The total dose corresponds to that of conventional mammography imaging. The technical procedure, including the number of levels, suitable anodes/filter combinations, angle regions of images and selection of reconstruction algorithms, is presently undergoing optimization. Previous studies on the clinical value of tomosynthesis have examined screening parameters, such as recall rate and detection rate as well as information on tumor extent for histologically proven breast tumors. More advanced techniques, such as contrast medium-enhanced tomosynthesis, are presently under development and dual-energy imaging is of particular importance.
Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Marchioninistr. 15, 81377 München, Deutschland. karin.hellerhoff@med.uni-muenchen.de
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D000465:Algorithms; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D004867:Equipment Design; D005260:Female; D005544:Forecasting; D005858:Germany; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation* / Q000639:trends; D021621:Imaging, Three-Dimensional / Q000295:instrumentation* / Q000639:trends; D008403:Mass Screening / Q000295:instrumentation*; D011829:Radiation Dosage; D015900:Radiography, Dual-Energy Scanned Projection / Q000295:instrumentation* / Q000639:trends; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000639:trends