P-C bond formation via P-H addition of a fluoroaryl phosphinic acid to ketones.
The synthesis, structure and reactivity of the fluoroaryl phosphinic acid HF(4)C(6)-P(O)HOH is reported and compared to a sterically comparable yet non-fluorinated analog with similar size. The fluoroaryl phosphinic acid undergoes reversible P-H addition to the carbonyl functionality of ketones under formation of a P-C bond which is retained in the resulting α-hydroxy phosphinic acid. The latter shows an extended 2D hydrogen bonded network in the solid state.
Department of Chemistry, Inorganic Section, University of Graz, Schubertstr. 1, 8010 Graz, Austria.
Andreas
A
Orthaber
Jörg H
JH
Albering
Ferdinand
F
Belaj
Rudolf
R
Pietschnig