AIDS-associated Penicillium marneffei infection of the central nervous system.
Penicillium marneffei is an important human immunodeficiency virus-associated opportunistic infection endemic in Southeast Asia. Central nervous system infection has not been described. We report the first case series of 21 human immunodeficiency virus-infected patients who presented with a syndrome consistent with acute central nervous system infection and who had Penicillium marneffei isolated from cerebrospinal fluid.
Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. thuyl@oucru.org
Thuy
T
Le
Nguyen
N
Huu Chi
Ngo T
NT
Kim Cuc
Tran Phu
TP
Manh Sieu
Cecilia M
CM
Shikuma
Jeremy
J
Farrar
Jeremy N
JN
Day
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001210:Asia, Southeastern; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis* / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D010407:Penicillium / Q000302:isolation & purification*; D016896:Treatment Outcome
D000935:Antifungal Agents