Nocturnal acid breakthrough on proton pump inhibitor therapy: to treat or not to treat.
Nocturnal acid breakthrough is misunderstood and infrequently requires treatment in everyday practice. There are important subgroups of patients in whom esophageal reflux occurs in the presence of nocturnal acid breakthrough in which treatment may be needed.
Division of Gastroenterology, Albert Einstein Medical Center, Thomas Jefferson University, 5401 Old York Road, Klein Building, Suite 363, Philadelphia, PA, 19141, USA. katzp@einstein.edu
Philip O
PO
Katz
Robert S
RS
Dudnick