Recovery of Candida dubliniensis and other Candida species from the oral cavity of subjects with periodontitis who had well-controlled and poorly controlled type 2 diabetes: a pilot study.
The goal of this study was to determine the prevalence of Candida dubliniensis and other Candida species from saliva samples and from subgingival plaque samples at periodontally healthy and periodontally diseased sites in subjects who had type 2 diabetes and periodontitis. Saliva and subgingival samples were obtained from 30 subjects with periodontitis: 15 with poorly controlled and 15 with well-controlled type 2 diabetes. Samples were analyzed for the presence of C. dubliniensis and other Candida species. Among subjects with poorly controlled diabetes, 53% were positive for C. albicans, 20% for C. glabrata, 6% for C. tropicalis, and 6% for C. parapsilosis. Among well-controlled subjects, 33% were positive for C. albicans and 13% for C. glabrata; none had C. tropicalis or C. parapsilosis. No samples were positive for C. dubliniensis in either group of subjects.
meltondds@gmail.com
John Jeffrey
JJ
Melton
Spencer W
SW
Redding
William R
WR
Kirkpatrick
Charles A
CA
Reasner
Gloria L
GL
Ocampo
Aruna
A
Venkatesh
Brian L
BL
Mealey
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002175:Candida / Q000302:isolation & purification*; D016022:Case-Control Studies; D003773:Dental Plaque / Q000382:microbiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood / Q000150:complications / Q000382:microbiology*; D010865:Pilot Projects; D012463:Saliva / Q000382:microbiology; D018709:Statistics, Nonparametric; D013357:Subgingival Curettage
D001786:Blood Glucose