Sexual motivation and anxiety-like behaviors of male rats after exposure to a trauma followed by situational reminders.
Experiencing a traumatic event can produce long-lasting impairments in affective and social behaviors. In humans, psychopathologies associated with exposure to a single traumatic event often are associated with varying degrees of sexual dysfunction. Similarly, in rats, exposure to a trauma results in long-lasting changes in social behaviors. The current investigation examined if the sexual and affective behaviors of male rats were impacted by exposure to a discrete traumatic event that was followed days later by reminders of the event. The initial trauma combined exposure to a foot shock and predator odor, followed 3 and 7 days later by reminders of the trauma in the absence of either stressor. A day after the final reminder, traumatized rats exhibited decreased sexual motivation indicated by prolonged mount and intromission latencies, although ejaculation latencies and post-ejaculatory intervals remained unchanged. Traumatized rats also exhibited marked increases in anxiety-like behavior in a novel environment as evidenced by longer latencies to begin feeding, decreased movement and ambulation, and fewer entries into the center of an open field. Taken together, the results of the current study suggest that exposure to a single traumatic event, followed by reminders of the event, affected the motivation of male rats to interact with a receptive female and increased their anxiety-like behaviors. Moreover, because posttraumatic stress disorder can arise from exposure to a single traumatic event and is associated with recurrent and intrusive thoughts related to the trauma, the current findings have implications for our understanding of this disorder.
Department of Psychology, Tulane University, New Orleans, LA, United States.
Wayne
W
Hawley
Elin
E
Grissom
Lisa
L
Keskitalo
Tyler
T
Hastings
Gary
G
Dohanich
D000704:Analysis of Variance; D000818:Animals; D001007:Anxiety / Q000209:etiology*; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal; D004195:Disease Models, Animal; D005106:Exploratory Behavior / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D008297:Male; D009042:Motivation / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012726:Sexual Behavior, Animal / Q000502:physiology*; D014947:Wounds and Injuries / Q000150:complications*