Cholestatic hepatitis and thrombocytosis in a secondary syphilis patient.
The incidence of acute hepatitis in syphilis patient is rare. First of all, our patient presented with hepatitis comorbid with thrombocytosis. To our knowledge, this is only the second report of syphilitic hepatitis with thrombocytosis. The 42-yr-old male complained of flu-like symptoms and skin eruptions on his palms and soles. Laboratory findings suggested an acute hepatitis and thrombocytosis. Serologic test results were positive for VDRL. He recovered from his symptoms and elevated liver related enzymes with treatment. Because syphilitic hepatitis can present without any typical signs of accompanying syphilis, syphilis should be considered as a possible cause in acute hepatitis patients.
Department of Internal Medicine, Chungbuk National University, College of Medicine and Medical Research Institute, Cheongju, Korea.
Gi Hyun
GH
Kim
Byeong Uk
BU
Kim
Ju Hee
JH
Lee
Yong Heok
YH
Choi
Hee Bok
HB
Chae
Seon Mee
SM
Park
Sei Jin
SJ
Youn
Ji Yeoun
JY
Lee
Tae Young
TY
Yoon
Rohyun
R
Sung
D000208:Acute Disease; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001663:Bilirubin / Q000097:blood; D004817:Epidermis / Q000473:pathology; D006505:Hepatitis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007565:Jaundice; D008297:Male; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D013587:Syphilis / Q000150:complications*; D013588:Syphilis Serodiagnosis; D013922:Thrombocytosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D000469:Alkaline Phosphatase; D001663:Bilirubin; D010401:Penicillin G Benzathine