High plasma concentration of beta-D-glucan after administration of sizofiran for cervical cancer.
A 69-year-old woman with a history of cervical cancer was admitted to our hospital for further investigation of abnormal shadows on her chest roentgenogram. Histologic examination of transbronchial lung biopsy specimens revealed epithelioid cell granuloma, and Mycobacterium intracellulare was detected in the bronchial lavage fluid. The plasma level of (1→3)-beta-d-glucan was very high, and this elevated level was attributed to administration of sizofiran for treatment of cervical cancer 18 years previously. Therefore, in patients with cervical cancer, it is important to confirm whether or not sizofiran has been administered before measuring (1→3)-beta-d-glucan levels.
Division of Respiratory Medicine,Matsue Red Cross Hospital,200 Horomachi, Matsue, Shimane, Japan. tokuun3200@yahoo.co.jp
Hirokazu
H
Tokuyasu
Kenichi
K
Takeda
Yuji
Y
Kawasaki
Yasuto
Y
Sakaguchi
Noritaka
N
Isowa
Eiji
E
Shimizu
Yasuto
Y
Ueda