Current approaches to trace analysis of pharmaceuticals and personal care products in the environment.
A large number of xenobiotics including pharmaceuticals and personal care products are continuously released into the environment. Effluents from sewage treatment plants are well known to be the major source for introduction of pharmaceuticals and personal care products into the aquatic system. In recent years, reliable methods have been established for residue analysis of these pollutants down to low ng/L levels. In this review, the different approaches to their trace determination are reviewed with special attention being paid to sample preparation procedures, state-of-the-art high-performance separation methods hyphenated with mass spectrometry, and immunochemical methods.
Johannes-Kepler-University, Institute of Analytical Chemistry, Altenbergerstrasse 69, A-4040 Linz, Austria. wolfgang.buchberger@jku.at
Wolfgang W
WW
Buchberger
D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D003358:Cosmetics / Q000737:chemistry*; D019075:Electrophoresis, Capillary; D008401:Gas Chromatography-Mass Spectrometry; D007118:Immunoassay; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000302:isolation & purification; D012722:Sewage / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000302:isolation & purification
D003358:Cosmetics; D004364:Pharmaceutical Preparations; D012722:Sewage; D014874:Water Pollutants, Chemical