Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes.
This review summarizes the recent progress on the biosynthesis of fumitremorgin-type alkaloids; that is, the identification of the biosynthetic gene clusters from genome sequences by genome mining and proof of gene function by molecular biological and biochemical investigations.
Philipps-Universität Marburg, Institut für Pharmazeutische Biologie und Biotechnologie, Marburg, Germany. shuming.li@staff.uni-marburg.de
Shu-Ming
SM
Li
D001203:Ascomycota / Q000235:genetics* / Q000378:metabolism*; D016681:Genome, Fungal; D026121:Indole Alkaloids / Q000378:metabolism*; D005810:Multigene Family; D009183:Mycotoxins / Q000096:biosynthesis / Q000235:genetics
D026121:Indole Alkaloids; D009183:Mycotoxins