Prooxidant/antioxidant ratio (ProAntidex) as a better index of net free radical scavenging potential.
The antioxidant activity of several Malaysian plant extracts was analyzed simultaneously with their pro-oxidant capacity. This ratio represents an index (ProAntidex) of the net free radical scavenging ability of whole plant extracts. We observed that ethanolic extracts of Nephelium lappaceum peel, Fragaria x ananassa leaf, Lawsonia inermis leaf, Syzygium aqueum leaf and grape seed had a lower Pro-Antidex than the commercially available Emblica™ extract which is an antioxidant agent with very low pro-oxidant activity. Among the aqueous extracts, Lawsonia inermis leaf, Nephelium mutobile leaf and grape seed had lower pro-oxidant activity compared to the Emblica™ extract. Among these extracts, aqueous extract of Nephelium mutobile leaf had a very low index of 0.05 compared to 0.69 for Emblica™. Most of the extracts had a far lower ProAntidex compared to the Vitamin C. The index enables us to identify extracts with high net free radical scavenging activity potential. The ProAntidex is beneficial as a screening parameter to the food industries and healthcare.
Department of Physiology, Faculty of Medicine, 50603, University of Malaya, Kuala Lumpur, Malaysia. lai_teng@siswa.um.edu.my
Lai Teng
LT
Ling
Uma D
UD
Palanisamy
Hwee Ming
HM
Cheng
D000975:Antioxidants / Q000737:chemistry*; D031985:Fragaria / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry*; D031564:Lawsonia Plant / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry; D027843:Vitis / Q000737:chemistry
D000975:Antioxidants; D016166:Free Radical Scavengers; D010936:Plant Extracts; D017382:Reactive Oxygen Species