Childhood adversity, mental disorder comorbidity, and suicidal behavior in schizotypal personality disorder.
Schizotypal personality disorder (SPD) is a serious and relatively common psychiatric disorder, yet remains understudied among the personality disorders. The current study examines the psychiatric correlates of SPD in a representative epidemiologic sample, utilizing data from the National Epidemiological Survey on Alcohol and Related Conditions (N = 34,653). Multiple logistic regression compared people with SPD to the general population across a broad range of childhood adversities, comorbid psychiatric disorders, and suicidal behavior. SPD was strongly associated with many adverse childhood experiences. After adjusting for confounding factors, SPD was independently associated with major depression and several anxiety disorders, including post-traumatic stress disorder. Interestingly, SPD was more strongly associated with borderline and narcissistic personality disorders than cluster A personality disorders. Individuals with SPD were also more likely to attempt suicide. As a whole, these results suggest that individuals with SPD experience significant morbidity and may be at increased risk of mortality.
Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.
Vanessa
V
Lentz
Jennifer
J
Robinson
James M
JM
Bolton
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002649:Child Abuse / Q000523:psychology* / Q000706:statistics & numerical data*; D002650:Child Abuse, Sexual / Q000523:psychology* / Q000706:statistics & numerical data*; D015897:Comorbidity; D017579:Domestic Violence / Q000523:psychology* / Q000706:statistics & numerical data*; D005260:Female; D006306:Health Surveys; D006801:Humans; D007406:Interview, Psychological; D008016:Life Change Events; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology* / Q000523:psychology*; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012569:Schizotypal Personality Disorder / Q000453:epidemiology* / Q000523:psychology*; D012959:Socioeconomic Factors; D013223:Statistics as Topic; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data*; D055815:Young Adult