Hypergammaglobulinemic purpura of Waldenström.
Hypergammaglobulinemic purpura of Waldenström is a rare syndrome that includes recurrent episodic purpura occurring mainly on the lower extremities and dorsum of the feet. The hallmark of this condition is polyclonal hypergammaglobulinemia primarily composed of IgG. Although the condition generally is benign, it may herald an underlying connective tissue disease or hematologic malignancy. We report a case of a 47-year-old woman with episodic purpura of 3 years' duration associated with Raynaud phenomenon.
Mount Sinai School of Medicine, New York, New York, USA.
Amylynne
A
Frankel
Adam
A
Ingraffea
Maureen
M
Massé
Hua
H
Zhou
D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008875:Middle Aged; D011694:Purpura, Hyperglobulinemic / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D011928:Raynaud Disease / Q000150:complications*
D007074:Immunoglobulin G