[Secondary metabolites of mangrove endophytic fungus BL321 in the South China Sea].
OBJECTIVE
To study the secondary metabolites of mangrove endophytic fungus BL321.


METHODS
The compounds were isolated by chromatographic technique. The structures were identified by comprehensive physico-chemical properties and spectral methods.


RESULTS
Five compounds were isolated and identified as 3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphtho[2,3-b]furan-5-carboxylic acid(1), cytochalasin C(2), cytochalasin D(3), 19,20-epoxycytochalasin C(4), ergosterol(5).


CONCLUSIONS
Compound 1 is isolated from nature for the first time. Further more, several kinds of strong bioactive compounds were islolate from this fungus indicate that it may develop to be medical source microorganism.
School of Chemicsty and Chemical Engineering, Sun Yat-sen University/Key Laboratory of Function Molecule from Marine Microorganism Department of Education of Guangdong Provience, Guangzhou 510275, China.
Yong-Xiang
YX
Song
Huan-Ge
HG
Ma
Jun
J
Wang
Lan
L
Liu
Zhi-Gang
ZG
She
Yong-Cheng
YC
Lin
D002681:China; D015638:Cytochalasin D / Q000737:chemistry / Q000302:isolation & purification; D003572:Cytochalasins / Q000737:chemistry / Q000302:isolation & purification*; D004875:Ergosterol / Q000737:chemistry / Q000302:isolation & purification*; D005658:Fungi / Q000737:chemistry* / Q000378:metabolism; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D043982:Rhizophoraceae / Q000382:microbiology*
C488245:19,20-epoxycytochalasin Q; C558178:3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphtho(2,3-b)furan-5-carboxylic acid; D003572:Cytochalasins; D005663:Furans; D009281:Naphthalenes; C031582:cytochalasin C; D015638:Cytochalasin D; D004875:Ergosterol