title: Licensing PPARγ to work in macrophages.
abstract: The mechanisms that direct cell-type-specific peroxisome proliferator-activated receptor (PPAR) gene programs are poorly understood. In this issue of Immunity, Szanto et al. (2010) identify signal transducer and activator of transcription 6 as a transcriptional switch that licenses PPARγ-dependent gene expression in macrophages and dendritic cells.
authors.affiliation: Howard Hughes Medical Institute and Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
authors.forename: Claudio J
authors.initials: CJ
authors.lastname: Villanueva
authors.forename: Peter
authors.initials: P
authors.lastname: Tontonoz