title: The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries.
abstract: Abdominal aortic aneurysm (AAA) represents a degenerative disease process of the abdominal aorta that results in dilation and permanent remodeling of the arterial wall. A fluid structure interaction (FSI) parametric study was conducted to evaluate the progression of aneurysmal disease and its possible implications on risk of rupture. Two parametric studies were conducted using (i) the iliac bifurcation angle and (ii) the AAA neck angulation. Idealized streamlined AAA geometries were employed. The simulations were carried out using both isotropic and anisotropic wall material models. The parameters were based on CT scans measurements obtained from a population of patients. The results indicate that the peak wall stresses increased with increasing iliac and neck inlet angles. Wall shear stress (WSS) and fluid pressure were analyzed and correlated with the wall stresses for both sets of studies. An adaptation response of a temporary reduction of the peak wall stresses seem to correlate to a certain extent with increasing iliac angles. For the neck angulation studies it appears that a breakdown from symmetric vortices at the AAA inlet into a single larger vortex significantly increases the wall stress. Our parametric FSI study demonstrates the adaptation response during aneurysmal disease progression and its possible effects on the AAA risk of rupture. This dependence on geometric parameters of the AAA can be used as an additional diagnostic tool to help clinicians reach informed decisions in establishing whether a risky surgical intervention is warranted.
authors.affiliation: Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.
authors.forename: Michalis
authors.initials: M
authors.lastname: Xenos
authors.forename: Yared
authors.initials: Y
authors.lastname: Alemu
authors.forename: Dan
authors.initials: D
authors.lastname: Zamfir
authors.forename: Shmuel
authors.initials: S
authors.lastname: Einav
authors.forename: John J
authors.initials: JJ
authors.lastname: Ricotta
authors.forename: Nicos
authors.initials: N
authors.lastname: Labropoulos
authors.forename: Apostolos
authors.initials: A
authors.lastname: Tassiopoulos
authors.forename: Danny
authors.initials: D
authors.lastname: Bluestein
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D001019:Aortic Rupture / Q000473:pathology / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology; D006801:Humans; D007083:Iliac Artery / Q000473:pathology; D008875:Middle Aged; D008955:Models, Cardiovascular; D012039:Regional Blood Flow / Q000502:physiology; D013314:Stress, Mechanical; D014057:Tomography, X-Ray Computed