title: NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand.
abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively and displays a large degree of genetic variability, particularly at the nonstructural protein (nsp) 2 gene. This is the first study determining genetic variation of the nsp2 of Thai PRRSV isolates. The results showed that 9 out of 10 Thai PRRSV isolates were nsp2-truncated viruses that might have evolved from a virus previously introduced in the past, but not from one recently introduced.
authors.affiliation: Department of Veterinary Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Roongtham
authors.initials: R
authors.lastname: Kedkovid
authors.forename: Suparlark
authors.initials: S
authors.lastname: Nuntawan Na Ayudhya
authors.forename: Alongkorn
authors.initials: A
authors.lastname: Amonsin
authors.forename: Roongroje
authors.initials: R
authors.lastname: Thanawongnuwech
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005838:Genotype; D008969:Molecular Sequence Data; D009656:North America; D011110:Polymorphism, Genetic; D019316:Porcine respiratory and reproductive syndrome virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012367:RNA, Viral / Q000235:genetics; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D013552:Swine; D013785:Thailand; D017361:Viral Nonstructural Proteins / Q000235:genetics*
chemical_list: D012367:RNA, Viral; D017361:Viral Nonstructural Proteins