title: Fat tissue alters quadriceps response to femoral nerve magnetic stimulation.
abstract: OBJECTIVE
  We investigate the influence that inguinal fat has on maximal quadriceps response to femoral nerve magnetic stimulation.
  
  
  METHODS
  Vastus lateralis M-wave amplitude and quadriceps twitch peak torque were measured (i) in lean and overweight subjects and (ii) when slices of pig fat ranging from 2 to 18 mm in thickness were placed between the coil and the nerve.
  
  
  RESULTS
  In overweight group, the maximal response could not be elicited when intensity was ≤90% and ≤85% of maximal power for twitch torque and M-wave amplitude, respectively. The maximal response was obtained at 80% of maximal power in the lean group. Negative correlations between relative twitch torque changes and inguinal thickness were observed. Fat thickness altered quadriceps response at 14 mm and 8 mm in the lean and overweight groups, respectively.
  
  
  CONCLUSIONS
  The capacity of femoral nerve magnetic stimulation to deliver supramaximal stimulation is altered when fat thickness below the coil increases.
  
  
  CONCLUSIONS
  Special caution should be taken by clinicians when overweight or obese subjects are tested using femoral nerve magnetic stimulation.
authors.affiliation: Université de Lyon, F-42023, Saint-Etienne, France.
authors.forename: Katja
authors.initials: K
authors.lastname: Tomazin
authors.forename: Samuel
authors.initials: S
authors.lastname: Verges
authors.forename: Nicolas
authors.initials: N
authors.lastname: Decorte
authors.forename: Alain
authors.initials: A
authors.lastname: Oulerich
authors.forename: Nicola A
authors.initials: NA
authors.lastname: Maffiuletti
authors.forename: Guillaume Y
authors.initials: GY
authors.lastname: Millet
mesh_terms: D000273:Adipose Tissue / Q000502:physiology*; D000328:Adult; D001823:Body Composition / Q000502:physiology; D003627:Data Interpretation, Statistical; D004574:Electromagnetic Fields; D004576:Electromyography; D005267:Femoral Nerve / Q000502:physiology*; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology; D007719:Knee Joint / Q000294:innervation / Q000502:physiology; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D050177:Overweight / Q000503:physiopathology; D052097:Quadriceps Muscle / Q000502:physiology; D011999:Recruitment, Neurophysiological / Q000502:physiology; D012885:Skinfold Thickness