title: Electrochemical sensing for caspase 3 activity and inhibition using quantum dot functionalized carbon nanotube labels.
abstract: A novel electrochemical sensing platform for sensitive determination of caspase 3 activity and inhibition was developed by combining the site-specific recognition and cleavage of the DEVD-peptide with quantum dots as signal amplification.
authors.affiliation: Key Lab of Analytical Chemistry for Life Science (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P.R. China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Zhang
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Zheng
authors.forename: Fang-Fang
authors.initials: FF
authors.lastname: Cheng
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Zhu
mesh_terms: D000595:Amino Acid Sequence; D015374:Biosensing Techniques / Q000379:methods*; D053148:Caspase 3 / Q000378:metabolism*; D061945:Caspase Inhibitors; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005296:Ferrous Compounds / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D000075163:Metallocenes; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D045663:Quantum Dots; D013379:Substrate Specificity
chemical_list: D061945:Caspase Inhibitors; D005296:Ferrous Compounds; D000075163:Metallocenes; D037742:Nanotubes, Carbon; D010455:Peptides; D006046:Gold; D053148:Caspase 3; C004998:ferrocene