title: Grand challenge commentary: Synthetic immunology to engineer human immunity.
abstract: Rationally designing new strategies to control the human immune response stands as a key challenge for the scientific community. Chemical biologists have the opportunity to address specific issues in this area that have important implications for both basic science and clinical medicine.
authors.affiliation: Department of Chemistry, Yale University, New Haven, Connecticut, USA. david.spiegel@yale.edu
authors.forename: David A
authors.initials: DA
authors.lastname: Spiegel
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D006801:Humans; D007107:Immune System / Q000737:chemistry* / Q000187:drug effects*; D007109:Immunity / Q000187:drug effects*; D007111:Immunity, Cellular / Q000187:drug effects; D054852:Small Molecule Libraries; D058615:Synthetic Biology / Q000639:trends*; D014612:Vaccines / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D054852:Small Molecule Libraries; D014612:Vaccines