title: Tree nut allergy, egg allergy, and asthma in children.
abstract: BACKGROUND
  Children with food allergies often have concurrent asthma.
  
  
  OBJECTIVE
  The authors aimed to determine the prevalence of asthma in children with food allergies and the association of specific food allergies with asthma.
  
  
  METHODS
  Parental questionnaire data regarding food allergy, corroborated by allergic sensitization were completed for a cohort of 799 children with food allergies. Multivariate regression analysis tested the association between food allergy and reported asthma.
  
  
  RESULTS
  In this cohort, the prevalence of asthma was 45.6%. After adjusting for each food allergy, environmental allergies, and family history of asthma, children with egg allergy (odds ratio [OR] = 2.0; 95% confidence interval [CI] = 1.3-3.2; P < .01) or tree nut allergy (OR = 2.0; 95% CI = 1.1-3.6; P = .02) had significantly greater odds of report of asthma.
  
  
  CONCLUSIONS
  There is a high prevalence of asthma in the food-allergic pediatric population. Egg and tree nut allergy are significantly associated with asthma, independent of other risk factors.
authors.affiliation: Children's Hospital Boston, 300 Longwood Ave., Boston, MA 02115, USA.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Gaffin
authors.forename: William J
authors.initials: WJ
authors.lastname: Sheehan
authors.forename: Jaclyn
authors.initials: J
authors.lastname: Morrill
authors.forename: Munevver
authors.initials: M
authors.lastname: Cinar
authors.forename: Irene M
authors.initials: IM
authors.lastname: Borras Coughlin
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Sawicki
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Twarog
authors.forename: Michael C
authors.initials: MC
authors.lastname: Young
authors.forename: Lynda C
authors.initials: LC
authors.lastname: Schneider
authors.forename: Wanda
authors.initials: W
authors.lastname: Phipatanakul
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology*; D001900:Boston / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D021181:Egg Hypersensitivity / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D021184:Nut Hypersensitivity / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult