title: [Factors affecting intima-media thickness in carotid arteries in diabetes mellitus of the young].
abstract: The aim of the work was to measure intima-media thickness IMT), study lipid and carbohydrate metabolism and factors contributing to the development of vascular complications in type 1 and 2 diabetes mellitus (DM) of the young. It included 63 patients aged 18-40 years (40 with DM1 and 13 with DM2). Glycated hemoglobin was measured on a AzSYM immunoenzyme analyzer, lipid metabolism studied using a Cobas Integra 400 Plus analyzer, and IMT estimated based on the ultrasound technique (Volision--750 Exert with 10 MHz sensors). Patients with DM of the young showed higher IMT values than age-matched healthy subjects. IMT tended to increase after the age of 33 years and with duration of DM. DM did not cause a decrease of blood HDL levels. Smoking had negative effect on the vascular wall in DM patients.
authors.forename: B M
authors.initials: BM
authors.lastname: Zhumanova
authors.forename: S Zh
authors.initials: SZh
authors.lastname: Asfendiiarova
authors.forename: R M
authors.initials: RM
authors.lastname: Zaslavskaia
authors.forename: R N
authors.initials: RN
authors.lastname: Berishev
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D012907:Smoking / Q000473:pathology; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000473:pathology*; D017540:Tunica Media / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin