title: Preservation of autonomic nerves in laparoscopic total radical hysterectomy.
abstract: OBJECTIVE
  The aim of this study was to evaluate the feasibility, complications, margin status, and functional outcome (on urinary and sexual functions) of nerve-sparing radical hysterectomy (NSRH) performed laparoscopically.
  
  
  METHODS
  Patients with cervical carcinoma of stage Ia2 and Ib1 underwent laparoscopic NSRH along with pelvic lymphadenectomy. We performed the technique in simple comprehensible steps with anatomic delineation of the autonomic nerves and selective cutting of the uterine and cervical branches.
  
  
  RESULTS
  Laparoscopic NSRH was feasible in 85.7% of patients. Mean operative time was 160 minutes and all 7 patients had clear surgical margins. There were no complications and no blood transfusions were required. The median hospital stay was 3 days. The median return time for normal bladder function was 2 days and none of them required catheterization beyond 2 weeks. The mean residual urine volume was <50 mL. Urodynamic studies performed at 3 weeks after the operation showed no impairment of maximum flow rate (maximal flow rate: 20 ± 2 mL). The postoperative results of sexual dysfunction were inconclusive.
  
  
  CONCLUSIONS
  Understanding this technique and the knowledge of laparoscopic anatomy of pelvic autonomic nerves is important in both benign and malignant pelvic surgeries. These preliminary results indicate that nerve sparing is easier done laparoscopically and its results are comparable to that of conventional laparoscopic radical hysterectomy in terms of lateral margin status and lymph node yield. Whether quality of life can be benefited by L-NRSH technique and its long-term oncological sequelae need further evaluation.
authors.affiliation: Galaxy Laparoscopy Institute, Pune, India. shase63@gmail.com
authors.forename: Shailesh P
authors.initials: SP
authors.lastname: Puntambekar
authors.forename: Anjali
authors.initials: A
authors.lastname: Patil
authors.forename: Sourabh N
authors.initials: SN
authors.lastname: Joshi
authors.forename: Neeraj V
authors.initials: NV
authors.lastname: Rayate
authors.forename: Seema S
authors.initials: SS
authors.lastname: Puntambekar
authors.forename: Geetanjali A
authors.initials: GA
authors.lastname: Agarwal
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D017776:Autonomic Pathways; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D010535:Laparoscopy; D008197:Lymph Node Excision; D008875:Middle Aged; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*