title: Myocardial fibrosis in desmin-related hypertrophic cardiomyopathy.
abstract: Desmin-related myopathy (DRM) is known to cause different types of cardiomyopathy. Late gadolinium enhancement cardiovascular magnetic resonance (CMR) has been shown to identify fibrosis in ischemic and non-ischemic cardiomyopathies. We present a rare case of desmin-related hypertrophic cardiomyopathy, CMR revealed fibrosis in the lateral wall of the left ventricle. CMR is superior to conventional echocardiography for the detection of myocardial fibrosis in desmin-related cardiomyopathy, which may be useful to detect early cardiac involvement and predict the patient prognosis.
authors.affiliation: Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, No, 2, Anzhen road, Chaoyang district, Beijing, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: He
authors.forename: Zhaoqi
authors.initials: Z
authors.lastname: Zhang
authors.forename: Daojun
authors.initials: D
authors.lastname: Hong
authors.forename: Qinyi
authors.initials: Q
authors.lastname: Dai
authors.forename: Tengyong
authors.initials: T
authors.lastname: Jiang
mesh_terms: D000293:Adolescent; D002312:Cardiomyopathy, Hypertrophic / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology; D003287:Contrast Media; D004252:DNA Mutational Analysis; D003893:Desmin / Q000235:genetics*; D005260:Female; D005355:Fibrosis; D019786:Gadolinium DTPA; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009206:Myocardium / Q000473:pathology*; D018979:Myositis, Inclusion Body / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D011237:Predictive Value of Tests; D017384:Sequence Deletion; D016277:Ventricular Function, Left
chemical_list: D003287:Contrast Media; D003893:Desmin; D019786:Gadolinium DTPA