title: The use of diffusion MRI in ischemic optic neuropathy and optic neuritis.
abstract: Ischemic optic neuropathy and optic neuritis are the most common causes of unilateral non-glaucomatous visual loss. While they have distinctive clinical features, they also share some overlapping profiles that make it difficult to clinically distinguish these two entities. MRI with gadolinium has been proven to be helpful to confirm the diagnosis of optic neuritis, but ischemic optic neuropathy remains a clinical diagnosis. Diffusion MRI, a newly advanced technique, has been used in studying the pathophysiology of optic neuritis, but its use in ischemic optic neuropathy is limited. Diffuse MRI may potentially be of help to diagnose ischemic optic neuropathy.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
authors.forename: Ming
authors.initials: M
authors.lastname: He
authors.forename: Dean
authors.initials: D
authors.lastname: Cestari
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Cunnane
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Rizzo
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging; D005682:Gadolinium; D006801:Humans; D009902:Optic Neuritis / Q000175:diagnosis*; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis*; D011868:Radioisotopes
chemical_list: D011868:Radioisotopes; D005682:Gadolinium