title: Serum cytokine responses in primary pneumonic plague patients.
abstract: The serum levels of interleukin-2 (IL-2), gamma interferon (IFN-γ), tumor necrosis factor alpha (TNF-α), IL-4, IL-6, and IL-10 of pneumonic plague patients were determined by enzyme-linked immunosorbent assay. IL-6 was the only elevated cytokine in the patients, and its level increased with a clear time course, indicating that IL-6 might be a prognostic marker for predicting the progression of plague.
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, No. 20 Dongdajie, Fentai, Beijing 100071, China.
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Wang
authors.forename: Zuyun
authors.initials: Z
authors.lastname: Wang
authors.forename: Zhaobiao
authors.initials: Z
authors.lastname: Guo
authors.forename: Baiqing
authors.initials: B
authors.lastname: Wei
authors.forename: Fuzhang
authors.initials: F
authors.lastname: Tian
authors.forename: Shouhong
authors.initials: S
authors.lastname: Yu
authors.forename: Haoran
authors.initials: H
authors.lastname: Wang
authors.forename: Hu
authors.initials: H
authors.lastname: Wang
authors.forename: Ruifu
authors.initials: R
authors.lastname: Yang
mesh_terms: D016207:Cytokines / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D010930:Plague / Q000276:immunology*; D013997:Time Factors; D015854:Up-Regulation
chemical_list: D016207:Cytokines; D015850:Interleukin-6