title: Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study.
abstract: BACKGROUND
  To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study.
  
  
  RESULTS
  Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the LADA patients' versus controls. The average adiponectin level for the LADA patients was 9.96 μg/ml compared to 6.4 μg/ml for Type 2 matched controls and 9.6 μg/ml for non-diabetic controls. Mean difference for the LADA-type 2 comparison was calculated after data was log transformed and showed a difference of 1.58 μg/ml (95%CI: 1.28-1.95, p = 0.0001). There was no significant difference between LADA and non-diabetic controls (p = 0.54).
  
  
  CONCLUSIONS
  Adiponectin levels are higher among people with LADA compared to those with type 2 diabetes and are equivalent to levels seen in non-diabetic controls. This suggests that risk of complications in LADA, as with type 1 diabetes may be related more to glycaemic control rather than to factors of the metabolic syndrome.
authors.affiliation: Senior Lecturer in Epidemiology and Public Health, College of Medicine, Swansea University, Swansea, SA2 8PP UK. s.brophy@swansea.ac.uk.
authors.forename: Sinead
authors.initials: S
authors.lastname: Brophy
authors.forename: Helen
authors.initials: H
authors.lastname: Davies
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Stephens
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Prior
authors.forename: Mark
authors.initials: M
authors.lastname: Atkinson
authors.forename: Stephen
authors.initials: S
authors.lastname: Bain
authors.forename: Rhys
authors.initials: R
authors.lastname: Williams