title: Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States.
abstract: OBJECTIVE
  To determine age-specific serum anti-Müllerian hormone (AMH) values for women presenting to U.S. fertility clinics.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Single clinical reference laboratory.
  
  
  METHODS
  A total of 17,120 women of reproductive age ranging from 24 to 50 years old.
  
  
  METHODS
  None.
  
  
  METHODS
  Determination of single-year median and mean AMH values with SDs.
  
  
  RESULTS
  Single-year-specific median, mean, and SD values are summarized in Table 1. Both median and mean AMH values decreased steadily in a manner highly correlated with advancing age. The average yearly decrease in the median serum AMH value was 0.2 ng/mL/year through age 35 and then diminished to 0.1 ng/mL/year after age 35. The rate of decline in mean AMH values was 0.2 ng/mL/year through age 40 and then diminished to 0.1 ng/mL/year thereafter.
  
  
  CONCLUSIONS
  Median and mean AMH levels decreased steadily with increasing age from 24 to 50 years of age. Such data may be of value to physicians and their patients who are considering reproductive options.
authors.affiliation: Maimonides Medical Center, Department of Obstetrics and Gynecology, Genesis Fertility and Reproductive Medicine, Brooklyn, New York, USA. drseifer@genesisfertility.com
authors.forename: David B
authors.initials: DB
authors.lastname: Seifer
authors.forename: Valerie L
authors.initials: VL
authors.lastname: Baker
authors.forename: Benjamin
authors.initials: B
authors.lastname: Leader
mesh_terms: D000328:Adult; D000367:Age Factors; D000375:Aging / Q000097:blood*; D000554:Ambulatory Care Facilities; D054304:Anti-Mullerian Hormone / Q000032:analysis / Q000097:blood*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007246:Infertility / Q000097:blood* / Q000628:therapy; D008875:Middle Aged; D012016:Reference Values; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies; D014481:United States; D055815:Young Adult
chemical_list: D054304:Anti-Mullerian Hormone