title: Comparison of pandemic and seasonal influenza reveals higher mortality and increased prevalence of shock in children with severe h1n1/09 infection.
abstract: Comparison of the clinical features of H1N1/09 and previous years' influenza A cases reveals that, in children presenting with severe disease, H1N1/09 influenza is associated with an increased prevalence of shock, duration of admission, and mortality. This was not attributable to demographic differences or underlying disease. H1N1/09 influenza is associated with more severe diseases than those with previous years' influenza A strains.
authors.affiliation: Section of Paediatrics, Division of Infectious Disease, Imperial College, London, UK. Jethro.Herberg@imperial.ac.uk
authors.forename: Jethro A
authors.initials: JA
authors.lastname: Herberg
authors.forename: Kelsey D J
authors.initials: KD
authors.lastname: Jones
authors.forename: Stéphane
authors.initials: S
authors.lastname: Paulus
authors.forename: Stuart
authors.initials: S
authors.lastname: Gormley
authors.forename: David
authors.initials: D
authors.lastname: Muir
authors.forename: Mehrengise
authors.initials: M
authors.lastname: Cooper
authors.forename: Michael
authors.initials: M
authors.lastname: Levin
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000472:pathogenicity*; D007251:Influenza, Human / Q000150:complications / Q000401:mortality / Q000473:pathology* / Q000821:virology*; D007902:Length of Stay; D008297:Male; D015995:Prevalence; D012769:Shock / Q000453:epidemiology* / Q000401:mortality