title: Spontaneous odontoameloblastoma in a female Sprague Dawley rat.
abstract: The present report describes a spontaneously developing, highly infiltrative, and expansile neoplasm in the mandible of a 9-month-old female Sprague Dawley rat. The lesion consisted of abundant odontogenic epithelium with induction of osteodentin in the adjacent mesenchyme and was classified therefore as an odontoameloblastoma. Odontoameloblastomas are reported uncommonly in domestic animals, and the histologic and histochemical features of this neoplasm are reported herein along with a review of the veterinary literature.
authors.affiliation: Department of Veterinary Pathology, 2740 Veterinary Medicine, Iowa State University, Ames, IA 50011, USA. burrough@iastate.edu
authors.forename: Eric R
authors.initials: ER
authors.lastname: Burrough
authors.forename: Ronald K
authors.initials: RK
authors.lastname: Myers
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Whitley
mesh_terms: D000564:Ameloblastoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D005260:Female; D008339:Mandibular Neoplasms / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012376:Rodent Diseases / Q000473:pathology*