title: The traceless Staudinger ligation for indirect 18F-radiolabelling.
abstract: The Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.
authors.affiliation: University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
authors.forename: Laurence
authors.initials: L
authors.lastname: Carroll
authors.forename: Sophie
authors.initials: S
authors.lastname: Boldon
authors.forename: Romain
authors.initials: R
authors.lastname: Bejot
authors.forename: Jane E
authors.initials: JE
authors.lastname: Moore
authors.forename: Jérôme
authors.initials: J
authors.lastname: Declerck
authors.forename: Véronique
authors.initials: V
authors.lastname: Gouverneur
mesh_terms: D004952:Esters / Q000737:chemistry*; D005462:Fluorine Radioisotopes / Q000737:chemistry; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D004952:Esters; D005462:Fluorine Radioisotopes; D010720:Phosphines; D013438:Sulfhydryl Compounds; C044646:phosphine