title: Hemodynamic correlates of visuomotor motor adaptation by functional Near Infrared Spectroscopy.
abstract: The development of rehabilitation engineering technologies such as the design of smart prosthetics necessitates a deep understanding of brain mechanisms engaged in ecological situations when human interact with new tools and/or environments. Thus, we aimed to investigate potential hemodynamic signatures reflecting the level of cognitive-motor performance and/or the internal or mental states of individuals when learning a novel tool with unknown properties. These markers were derived from functional Near Infrared Spectroscopy (fNIR) signals. Our results indicate an increased level of oxy-hemoglobin in prefrontal sensors associated with enhanced kinematics during early compared with late learning. This is consistent with previous neuroimaging studies that revealed a higher contribution of prefrontal areas during early compare to late adaptation learning. These non-invasive functional hemodynamic markers may play a role in bioengineering applications such as smart neuroprosthesis and brain monitoring where adaptive behavior is important.
authors.affiliation: Department of Kinesiology and Graduate Program in Neuroscience and Cognitive Science, University of Maryland, College Park, MD 20742, USA. rodolphe@umd.edu
authors.forename: Rodolphe J
authors.initials: RJ
authors.lastname: Gentili
authors.forename: Cyrus
authors.initials: C
authors.lastname: Hadavi
authors.forename: Hasan
authors.initials: H
authors.lastname: Ayaz
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Shewokis
authors.forename: Jose L
authors.initials: JL
authors.lastname: Contreras-Vidal
mesh_terms: D000465:Algorithms; D001696:Biomechanical Phenomena; D001931:Brain Mapping / Q000379:methods; D003071:Cognition; D003952:Diagnostic Imaging / Q000379:methods; D006439:Hemodynamics; D006801:Humans; D015233:Models, Statistical; D009010:Monte Carlo Method; D009048:Motor Skills; D010108:Oxyhemoglobins / Q000737:chemistry; D012815:Signal Processing, Computer-Assisted; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D014785:Vision, Ocular
chemical_list: D010108:Oxyhemoglobins