title: A three-dimensional bioprinting system for use with a hydrogel-based biomaterial and printing parameter characterization.
abstract: Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three-dimensional (3D) structures. It provides high-precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composition ability. Bioprinting utilizes a computer-controlled 3D printer mechanism for 3D biological structure construction. To implement minimal pattern width in a hydrogel-based bioprinting system, a study on printing characteristics was performed by varying printer control parameters. The experimental results showed that printing pattern width depends on associated printer control parameters such as printing flow rate, nozzle diameter, and nozzle velocity. The system under development showed acceptable feasibility of potential use for accurate printing pattern implementation in tissue engineering applications and is another example of novel techniques for regenerative medicine based on computer-aided biofabrication system.
authors.affiliation: Korea Artificial Organ Center, Korea University, Seoul, Korea.
authors.forename: Seung-Joon
authors.initials: SJ
authors.lastname: Song
authors.forename: Jaesoon
authors.initials: J
authors.lastname: Choi
authors.forename: Yong-Doo
authors.initials: YD
authors.lastname: Park
authors.forename: Jung-Joo
authors.initials: JJ
authors.lastname: Lee
authors.forename: So Young
authors.initials: SY
authors.lastname: Hong
authors.forename: Kyung
authors.initials: K
authors.lastname: Sun
mesh_terms: D021522:Bioartificial Organs; D001672:Biocompatible Materials; D017076:Computer-Aided Design; D004867:Equipment Design; D006820:Hyaluronic Acid; D020100:Hydrogels; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels; D006820:Hyaluronic Acid