title: [The specific features of left cardiac cavity remodeling in patients with chronic obstructive pulmonary disease and chronic cor pulmonale].
abstract: OBJECTIVE
  To study left ventricular structural and functional changes in patients with chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP) at different stages of a cardiac remodeling process.
  
  
  METHODS
  Echocardiography was used to examine 98 patients with COPD complicated by the development of CCP in a number of cases. The significant signs of CCP were absent in 19 patients; the signs of compensated and decompensated CCP in 41 and 38 patients, respectively.
  
  
  RESULTS
  In the patients with COPD, the formation of CCP during remodeling of the heart involves its left cavities whose changes lie in the occurrence of left ventricular (LV) diastolic dysfunction, mainly of the restrictive type, in ventricular spherization, higher myocardial systolic tension, in tendencies towards increases in LV mass index, left atrial sizes, and in the indices reflecting LV systolic dysfunction. The LV diastolic dysfunction correlates with the degree of right ventricular hypertrophy and dilatation and the presence of complete right bundle-branch block.
  
  
  CONCLUSIONS
  Progressive worsening of diagnostic filling of the left ventricle and its systolic function is an additional factor aggravating hemodynamic disorders in patients with COPD and CCP, which should be kept in mind on choosing an appropriate therapy for patients with CCP.
authors.forename: A V
authors.initials: AV
authors.lastname: Strutynskiĭ
authors.forename: R G
authors.initials: RG
authors.lastname: Bakaev
authors.forename: A B
authors.initials: AB
authors.lastname: Glazunov
authors.forename: E N
authors.initials: EN
authors.lastname: Banzeliuk
authors.forename: N K
authors.initials: NK
authors.lastname: Moshkova
authors.forename: A A
authors.initials: AA
authors.lastname: Reĭsner
authors.forename: S V
authors.initials: SV
authors.lastname: Shavurdina
authors.forename: D V
authors.initials: DV
authors.lastname: Vinogradova
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003971:Diastole / Q000502:physiology; D004452:Echocardiography; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D011660:Pulmonary Heart Disease / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*; D020257:Ventricular Remodeling