title: A comprehensive meta-analysis of the risk of suicide in eating disorders.
abstract: OBJECTIVE
  Past meta-analyses on suicide in eating disorders included few available studies.
  
  
  METHODS
  PubMed/Medline search for papers including sample n ≥40 and follow-up ≥5 years: 40 studies on anorexia nervosa (AN), 16 studies on bulimia nervosa (BN), and three studies on binge eating disorder (BED) were included.
  
  
  RESULTS
  Of 16,342 patients with AN, 245 suicides occurred over a mean follow-up of 11.1 years (suicide rate=0.124 per 100 person-years). Standardized mortality ratio (SMR) was 31.0 (Poisson 95% CI=21.0-44.0); a clear decrease in suicide risk over time was observed in recent decades. Of 1768 patients with BN, four suicides occurred over a mean follow-up of 7.5 years (suicide rate=0.030 per 100 person-years): SMR was 7.5 (1.6-11.6). No suicide occurred among 246 patients with BED (mean follow-up=5.3 years).
  
  
  CONCLUSIONS
  AN and BN share many risk factors for suicide: the factors causing lower suicide rates per person-year in BN compared to AN should be investigated.
authors.affiliation: Centro Medico Genneruxi, Via Costantinopoli 42, Cagliari, Italy. apreti@tin.it
authors.forename: A
authors.initials: A
authors.lastname: Preti
authors.forename: M B L
authors.initials: MB
authors.lastname: Rocchi
authors.forename: D
authors.initials: D
authors.lastname: Sisti
authors.forename: M V
authors.initials: MV
authors.lastname: Camboni
authors.forename: P
authors.initials: P
authors.lastname: Miotto
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000523:psychology; D056912:Binge-Eating Disorder / Q000523:psychology; D052018:Bulimia Nervosa / Q000523:psychology; D001068:Feeding and Eating Disorders / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D013405:Suicide / Q000523:psychology* / Q000706:statistics & numerical data; D055815:Young Adult