title: Comparison of complex fractionated atrial electrograms at cellular scale using numerical and experimental models.
abstract: This study investigates the existence of the pseudo complex fractionated atrial electrogram (CFAE) at cellular level. Our assumptions are based on the fact that CFAEs are linked to the generation of the spiral waves. These are created using a numerical model and an experimental model of in vitro culture of neonatal rats cardiac cells. Pseudo bipolar electrograms resulting from these two models are compared qualitatively and some patterns could be identified as CFAE signature.
authors.affiliation: Laboratory LE2I UMR CNRS 5158, Université de Bourgogne, 9 avenue Alain Savary, BP47870, 21078 Dijon, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Navoret
authors.forename: Binbin
authors.initials: B
authors.lastname: Xu
authors.forename: Sabir
authors.initials: S
authors.lastname: Jacquir
authors.forename: Stéphane
authors.initials: S
authors.lastname: Binczak
mesh_terms: D000200:Action Potentials; D000818:Animals; D001281:Atrial Fibrillation / Q000503:physiopathology*; D001683:Biological Clocks; D003198:Computer Simulation; D004562:Electrocardiography / Q000379:methods; D006325:Heart Atria / Q000503:physiopathology*; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular; D032383:Myocytes, Cardiac