title: Localized aquadynia responsive to clonidine in a 13-year-old girl.
abstract: A 13-year-old girl sought medical care for pain in both palms that consistently occurred after brief exposure to water and resolved spontaneously 20 to 30 minutes after immersion. The pain was not associated with wrinkling of the palms. After excluding other causes of acrodynia and water-induced discomfort, we diagnosed the patient as having idiopathic localized aquadynia. Treatment with systemic clonidine led to a substantial improvement in her symptoms. To our knowledge, this patient represents the only fifth reported case of aquadynia and the first child affected by this enigmatic condition.
authors.affiliation: Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: Julia S
authors.initials: JS
authors.lastname: Lehman
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Kuntz
authors.forename: Dawn M R
authors.initials: DM
authors.lastname: Davis
mesh_terms: D000293:Adolescent; D001706:Biopsy; D003000:Clonidine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007101:Immersion / Q000009:adverse effects*; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D013565:Sympatholytics / Q000627:therapeutic use; D014867:Water / Q000009:adverse effects*
chemical_list: D013565:Sympatholytics; D014867:Water; D003000:Clonidine