title: Idiopathic edema, a condition associated with pelvic pain and other symptoms in women, as a remedial cause of chronic cold induced urticaria.
abstract: OBJECTIVE
  To determine if the treatment of cold induced urticaria refractory to conventional antihistamine-type therapy would respond to treatment with sympathomimetic amines.
  
  
  METHODS
  Dextroamphetamine sulfate (15 mg) extended release capsules were prescribed to be taken daily in the morning.
  
  
  RESULTS
  The cold-induced urticaria completely disappeared and antihistamine therapy was discontinued.
  
  
  CONCLUSIONS
  Treatment of chronic refractory cold-induced urticaria effectively responds to treatment with sympathomimetic amines similar to other cases of chronic refractory urticaria that are not merely cold induced. Manifestation of idiopathic orthostatic edema, a condition predominantly of women, should always be considered in the differential diagnosis of baffling medical conditions.
authors.affiliation: The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: R
authors.initials: R
authors.lastname: Cohen
authors.forename: D
authors.initials: D
authors.lastname: Check
mesh_terms: D000293:Adolescent; D002908:Chronic Disease; D003080:Cold Temperature / Q000009:adverse effects*; D003913:Dextroamphetamine / Q000627:therapeutic use; D004351:Drug Resistance; D004487:Edema / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D017699:Pelvic Pain / Q000188:drug therapy / Q000209:etiology*; D011187:Posture / Q000502:physiology; D013566:Sympathomimetics / Q000627:therapeutic use; D014581:Urticaria / Q000188:drug therapy / Q000209:etiology*
chemical_list: D013566:Sympathomimetics; D003913:Dextroamphetamine