title: Fully integrated micro-separator with soft-magnetic micro-pillar arrays for filtrating lymphocytes.
abstract: A fully integrated micro-separator with soft-magnetic micro-pillar arrays has been developed, which merely employs one independent Lab-On-Chip to realize the lymphocytes isolation from the human whole blood. The simulation, fabrication and experiment are executed to realize this novel microseparator. The simulation results show that, the soft-magnetic micro-pillars array can amplify and redistribute the electromagnetic field generated by the microcoils. The tests certify desirable separation efficiency can be realized using this new separator at low current. No extra cooling system is required for such a micro-separator. This micro-separator can also be used to separate other target cells or particles with the same principle.
authors.affiliation: Norwegian Center of Expertise on Micro- and Nanotechnology, I.M.S.T./R.I., Vestfold University College, Norway. tao.dong@hive.no
authors.forename: Tao
authors.initials: T
authors.lastname: Dong
authors.forename: Qianhua
authors.initials: Q
authors.lastname: Su
authors.forename: Zhaochu
authors.initials: Z
authors.lastname: Yang
authors.forename: Frank
authors.initials: F
authors.lastname: Karlsen
authors.forename: Henrik
authors.initials: H
authors.lastname: Jakobsen
authors.forename: Eirik Bentzen
authors.initials: EB
authors.lastname: Egeland
authors.forename: Snorre
authors.initials: S
authors.lastname: Hjelseth
mesh_terms: D004867:Equipment Design; D005374:Filtration / Q000379:methods*; D006801:Humans; D008214:Lymphocytes; D008280:Magnetics