title: Complexation of nitrogen and sulphur donor Schiff's base ligand to Cr(III) and Ni(II) metal ions: synthesis, spectroscopic and antipathogenic studies.
abstract: 2,6-diacetyl pyridine based ligand was synthesized by the reaction of 2,6-diacetyl pyridine with thiocarbohydrazide in presence of acetic acid. The coordination compounds with Cr(III) and Ni(II) metal ions having [Cr(L)X]X2 and [Ni(L)X]X compositions (where L=ligand and X=NO3-, Cl- and CH3COO-) were synthesized and characterized by physicochemical and spectral studies. The studies like elemental analyses, molar conductance measurements, magnetic susceptibility measurements, IR, UV-Vis, NMR, mass and EPR reveal that the complexes are octahedral. The compounds were examined against the pathogenic fungal and bacterial strains like Alternaria brassicae, Aspergillus niger, Fusarium oxysporum, Xanthomonas compestris and Pseudomonas aeruginosa. A. niger causes the diseases Apergillosis and Otomycosis in humans.
authors.affiliation: Department of Chemistry, Zakir Husain College, University of Delhi, J.L. Nehru Marg, New Delhi 110002, India. sharmaamitk@yahoo.co.in
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Sharma
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology; D002857:Chromium / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D007477:Ions; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared; D013455:Sulfur / Q000737:chemistry*; D016959:Xanthomonas campestris / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D007477:Ions; D008024:Ligands; D012545:Schiff Bases; D002857:Chromium; D013455:Sulfur; D009532:Nickel; D009584:Nitrogen