title: Inhibition effects of the classical pathway complement of three Sorghum bicolor from South Korea.
abstract: The present study evaluated the anti-complement effects from organic solvent extracts of three varieties (Hwanggeumchal Sorghum, Chal Sorghum, and Heuin Sorghum) from Sorghum bicolor in classical pathway complement system. We have evaluated organic solvent extract from Sorghum bicolor varieties with regard to its anti-complement activity. Chal Sorghum ethyl acetate extract showed inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 38.7 μg/mL. This is the first report of anti-complement activity from Sorghum bicolor varieties.
authors.affiliation: Department of Applied Life science, Kon Kuk University, Seoul, South Korea.
authors.forename: Ill-Min
authors.initials: IM
authors.lastname: Chung
authors.forename: Myong-Jo
authors.initials: MJ
authors.lastname: Kim
authors.forename: Dong-Sik
authors.initials: DS
authors.lastname: Park
authors.forename: Hyung-In
authors.initials: HI
authors.lastname: Moon
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003171:Complement Pathway, Classical / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects; D006801:Humans; D020128:Inhibitory Concentration 50; D010936:Plant Extracts / Q000494:pharmacology*; D011817:Rabbits; D056910:Republic of Korea; D012756:Sheep; D045868:Sorghum / Q000737:chemistry*
chemical_list: D010936:Plant Extracts