title: A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience.
abstract: We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.
authors.affiliation: Department of Cell Biology Division, The Gujarat Cancer and Research Institute, NCH Campus, Asarwa, Ahmedabad - 380 016, India.
authors.forename: P J
authors.initials: PJ
authors.lastname: Trivedi
authors.forename: P S
authors.initials: PS
authors.lastname: Patel
authors.forename: M M
authors.initials: MM
authors.lastname: Brahmbhatt
authors.forename: B P
authors.initials: BP
authors.lastname: Patel
authors.forename: S B
authors.initials: SB
authors.lastname: Gajjar
authors.forename: E N
authors.initials: EN
authors.lastname: Dalal
authors.forename: S N
authors.initials: SN
authors.lastname: Shukla
authors.forename: P M
authors.initials: PM
authors.lastname: Shah
authors.forename: S R
authors.initials: SR
authors.lastname: Bakshi