title: Assessment of the depth of anesthesia based on symbolic dynamics of the EEG.
abstract: Methodologies based on symbolic dynamics have successfully demonstrated to reflect the nonlinear behavior of biological signals. In the present study, symbolic dynamics was applied to the electroencephalogram (EEG) in order to describe the level of depth of anesthesia. The EEG was transformed to symbol sequences. Words of three symbols were built from this symbolic series. The results obtained from the EEGs of 36 patients undergoing anesthesia showed that the probabilities of the word types were able to reflect the depth of anesthesia in a similar way to the auditory evoked potential index AAI, a commercial index.
authors.affiliation: Dept. ESAII, Centre for Biomedical Engineering Research, Universitat Politècnica de Catalunya, CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain.
authors.forename: Nadine
authors.initials: N
authors.lastname: Tupaika
authors.forename: Montserrat
authors.initials: M
authors.lastname: Vallverdu
authors.forename: Mathieu
authors.initials: M
authors.lastname: Jospin
authors.forename: Erik W
authors.initials: EW
authors.lastname: Jensen
authors.forename: Michel M F
authors.initials: MM
authors.lastname: Struys
authors.forename: Hugo E M
authors.initials: HE
authors.lastname: Vereecke
authors.forename: Andreas
authors.initials: A
authors.lastname: Voss
authors.forename: Pere
authors.initials: P
authors.lastname: Caminal
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000379:methods*; D016002:Discriminant Analysis; D004569:Electroencephalography / Q000379:methods*; D019277:Entropy; D005260:Female; D006801:Humans; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology; D013997:Time Factors; D055815:Young Adult
chemical_list: D015742:Propofol