title: Application of ion chromatography for the determination of inorganic ions, especially thiocyanates, in human semen samples as biomarkers of environmental tobacco smoke exposure.
abstract: Tobacco smoking constitutes a significant source of indoor air pollution. Various chemical compounds that are emitted during tobacco smoking can have a direct cytotoxic effect on spermatozoa by damaging DNA. There is some evidence that tobacco smoking in men could affect male fertility. The goals of this study were to find relationships between thiocyanates (as biomarkers of environmental tobacco smoke exposure) and other inorganic ions in human semen samples and present the effectiveness of the proposed sample preparation procedure combined with ion chromatography technique for the determination of inorganic ions, especially thiocyanates, in human semen samples collected from heavy, moderate, and passive smokers, as well as nonsmoking individuals.
authors.affiliation: Department of Analytical Chemistry, Chemical Faculty, Gdansk University of Technology, Gdánsk, Poland. ilonkademkowska@wp.pl
authors.forename: Ilona
authors.initials: I
authors.lastname: Demkowska
authors.forename: Żaneta
authors.initials: Ż
authors.lastname: Polkowska
authors.forename: Bogumiła
authors.initials: B
authors.lastname: Kiełbratowska
authors.forename: Jacek
authors.initials: J
authors.lastname: Namieśnik
mesh_terms: D015415:Biomarkers / Q000032:analysis; D002852:Chromatography, Ion Exchange; D006801:Humans; D019570:Inhalation Exposure; D008274:Magnesium / Q000032:analysis; D008297:Male; D009566:Nitrates / Q000032:analysis; D010710:Phosphates / Q000032:analysis; D057566:Self Report; D012661:Semen / Q000737:chemistry*; D012907:Smoking / Q000378:metabolism; D013048:Specimen Handling; D013431:Sulfates / Q000032:analysis; D013861:Thiocyanates / Q000032:analysis*; D014028:Tobacco Smoke Pollution
chemical_list: D015415:Biomarkers; D009566:Nitrates; D010710:Phosphates; D013431:Sulfates; D013861:Thiocyanates; D014028:Tobacco Smoke Pollution; D008274:Magnesium