title: Statistical genetic issues for genome-wide association studies.
abstract: Genotyping technology now allows the rapid and affordable generation of million-SNP profiles for humans, leading to considerable activity in association mapping. Similar activity is anticipated for many plant species, including Brassica. These plant association mapping activities will require the same care in quality control and quality assurance as for humans. The subsequent analyses may draw upon the same body of theory that is described here in the language of quantitative genetics.
authors.affiliation: Department of Biostatistics, University of Washington, Box 357232, Seattle, WA 98195-7232, USA. bsweir@u.washington.edu
authors.forename: Bruce S
authors.initials: BS
authors.lastname: Weir
mesh_terms: D003627:Data Interpretation, Statistical; D005787:Gene Frequency; D018745:Genome, Plant; D055106:Genome-Wide Association Study / Q000706:statistics & numerical data*; D005838:Genotype; D015810:Linkage Disequilibrium; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide