title: Time-variant analysis of linear and non-linear phase couplings of and between frequency components of EEG burst patterns in full-term newborns.
abstract: Time-variant (tv) phase-locking and synchronization characteristics of and between low-frequency (≤ 1.5 Hz) and high-frequency EEG oscillations (≥ 3.5 Hz) of the tracé alternant (TA) pattern in full-term newborns have been quantified to explore the origin of quadratic phase coupling (QPC, as non-linear phase coupling measure) between the frequency ranges 1 - 1.5 Hz ⇔ 3.5 - 4.5 Hz, which characterize the specific interactions of oscillations during the TA's burst activity. Using the Gabor transformation two measures of linear phase coupling, the phase-locking index (PLI) and the n:m phase synchronization index (PSI) have been determined. Phase-locking within the frequency ranges 1 -1.5 Hz and 3.5 - 4.5 Hz, and synchronization between both frequency ranges exists. These phase characteristics are significant 2 sec after burst onset and are associated with the maximum-values of the QPC(1 - 1.5 Hz ⇔ 3.5 - 4.5 Hz) which demonstrates that a specific neuronal coordination between the dynamics of phases and of amplitude-frequency dependencies must be underlying.
authors.affiliation: Institute for Medical Statistics, Computer Sciences and Documentation, Bernstein Group for Computational Neuroscience Jena, Friedrich Schiller University Jena, Germany. matthias.wacker@mti.uni-jena.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Wacker
authors.forename: Peter
authors.initials: P
authors.lastname: Putsche
authors.forename: Herbert
authors.initials: H
authors.lastname: Witte
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D001683:Biological Clocks / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D003198:Computer Simulation; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016014:Linear Models; D008297:Male; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D017711:Nonlinear Dynamics