title: Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature.
abstract: Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder described among patients with renal disease. Currently, no standard therapy exists, although therapeutic modalities have included plasmapheresis, extracorporeal photopheresis, sodium thiosulphate, imatinib and renal transplantation. We describe a patient with NSF who was physically debilitated and underwent renal transplantation. After transplantation, the patient's lesions improved clinically, and the patient was ambulatory. Despite developing worsening renal function, her lesions remained unchanged. We conclude that renal transplantation improves symptoms of NSF, and believe that in patients with NSF, careful consideration should be made for early renal transplantation.
authors.affiliation: Department of Renal Unit of Internal Medicine, Hachioji Medical Center of Tokyo Medical University, 1163 Tate-machi, Hachioji-shi, Tokyo 193-0998, Japan.
authors.forename: Madison C
authors.initials: MC
authors.lastname: Cuffy
authors.forename: Mansher
authors.initials: M
authors.lastname: Singh
authors.forename: Richard
authors.initials: R
authors.lastname: Formica
authors.forename: Evans
authors.initials: E
authors.lastname: Simmons
authors.forename: Ali K
authors.initials: AK
authors.lastname: Abu Alfa
authors.forename: Kacie
authors.initials: K
authors.lastname: Carlson
authors.forename: Michael
authors.initials: M
authors.lastname: Girardi
authors.forename: Shawn E
authors.initials: SE
authors.lastname: Cowper
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kulkarni
mesh_terms: D005260:Female; D006084:Graft Rejection / Q000209:etiology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D054989:Nephrogenic Fibrosing Dermopathy / Q000628:therapy*; D012871:Skin Diseases / Q000209:etiology*; D016896:Treatment Outcome