title: [Bipolar transurethral resection of the prostate versus monopolar transurethral prostatectomy: a pathological study in a canine model].
abstract: OBJECTIVE
  To compare the postoperative depths of the coagulation zones and pathological changes between bipolar transurethral resection of the prostate with plasmakinetic energy (PKRP) and monopolar transurethral prostatectomy (TURP) in canines.
  
  
  METHODS
  Twenty-five male dogs were randomly divided into a PKRP group (n = 12), a TURP group (n = 12) and a sham-operation control group (n = 1). The dogs were sacrificed, their prostates harvested at 0 week (immediately after surgery), 1 week, 2 weeks and 8 weeks postoperatively and sectioned for pathologic analysis and measurement of the coagulation zones.
  
  
  RESULTS
  At 0, 1 and 2 weeks after the operation, the coagulation depths were (237.73 +/- 20.12) microm, (113.03 +/- 16.65) microm and (106.01 +/- 16.36) microm in the PKRP group, and (200.75 +/-19.34) microm, (129.46 +/- 17.81) microm and (116.04 +/- 25.67) microm in the TURP group (P < 0.01). At 8 weeks, the coagulation zones completely peeled off and the wounds were covered by regenerated urothelial in both of the groups. At 0, 1, 2 and 8 weeks, different inflammatory reactions were observed in the prostates of the PKRP and TURP groups, with some glandular lumens beneath the coagulation zones expanded and epithelia damaged. However, none of these phenomena occurred in the sham-operation control group.
  
  
  CONCLUSIONS
  Pathologically, PKRP and TURP inflicted basically similar effects on the prostate of the canine. However, the coagulation zone was deeper intraoperatively and became thinner postoperatively with the former than with the latter, which suggests that PKRP causes less bleeding and less penetrative thermal damage than TURP.
authors.affiliation: Department of Urology, Xiangfan Central Hospital, Xiangfan, Hubei 441021, China. hxsurgeon@126.com
authors.forename: Xing
authors.initials: X
authors.lastname: Huang
authors.forename: Xing-Huan
authors.initials: XH
authors.lastname: Wang
authors.forename: Huai-Peng
authors.initials: HP
authors.lastname: Wang
authors.forename: Hong-Bo
authors.initials: HB
authors.lastname: Shi
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Ji
authors.initials: J
authors.lastname: Zhou
authors.forename: Zhi-Yun
authors.initials: ZY
authors.lastname: Yu
mesh_terms: D000818:Animals; D004285:Dogs; D004564:Electrocoagulation; D004598:Electrosurgery; D008297:Male; D011467:Prostate / Q000473:pathology* / Q000601:surgery; D020728:Transurethral Resection of Prostate / Q000379:methods*