title: Comparison of hematological and biochemical parameters in sheep naturally and persistently infected with a border disease virus.
abstract: In this study, we investigated the changes occurring in the activities of determining the biochemical and hematological parameters in persistently infected sheep with border disease virus (BDV) and control sheep. While cholesterol, aspartate aminotransferase, lactate dehydrogenase, high-density lipoprotein, and glucose parameters were found to be statistically different between control and BDV positive groups (p<0.01), total protein, alkaline phosphotase, creatine kinase, amylase, glucose, and high-density lipoprotein were found to be statistically different between control and persistently infected group (p<0.01). Interestingly, all groups were shown only mean corpuscular volume parameter was different (p<0.01). It was found that cholesterol, aspartate aminotransferase, amylase, high-density lipoprotein, and low-density lipoprotein parameters were different between PI and infected sheep (p<0.01). It was speculated that BDV might effect also the expression of low-density lipoprotein receptor and determination of the changes in BD and its clinical importance might contribute to the veterinarians and scientists studying in this area.
authors.affiliation: Department of Internal Medicine, School of Veterinary Medicine, Kirikkale University, 71451, Kirikkale, Turkey.
authors.forename: Serkal
authors.initials: S
authors.lastname: Gazyağci
authors.forename: Ahmet Kursat
authors.initials: AK
authors.lastname: Azkur
authors.forename: Osman
authors.initials: O
authors.lastname: Cağlayan
mesh_terms: D000818:Animals; D001772:Blood Cell Count / Q000662:veterinary; D001774:Blood Chemical Analysis / Q000662:veterinary; D001882:Border Disease / Q000097:blood / Q000276:immunology* / Q000821:virology; D018083:Border disease virus / Q000276:immunology*; D002353:Carrier State / Q000097:blood / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000276:immunology / Q000821:virology*; D018709:Statistics, Nonparametric
chemical_list: D006454:Hemoglobins