title: Extended-spectrum ß-lactamase production in Shigella flexneri.
abstract: Emergence of multidrug-resistant strains of Shigella is a growing concern across the globe. Third-generation cephalosporins are used for treating infections caused by multidrug-resistant Shigellae. However, resistance to these cephalosporin antibiotics due to extended-spectrum ß-lactamases, has emerged as a new problem. So far extended-spectrum ß-lactamases producing Shigella has not been reported from Pakistan. We report such a case in Shigella flexneri from an 8-year old girl with acute dysentery.
authors.affiliation: Department of Microbiology, Armed Forces Institute of Pathology, Rawalpindi. abdulsattardr79@yahoo.com
authors.forename: Abdul
authors.initials: A
authors.lastname: Sattar
authors.forename: Shahid Ahmed
authors.initials: SA
authors.lastname: Abbasi
authors.forename: Javaid
authors.initials: J
authors.lastname: Usman
authors.forename: Farah
authors.initials: F
authors.lastname: Faqir
authors.forename: Fatima
authors.initials: F
authors.lastname: Kaleem
authors.forename: Faisal
authors.initials: F
authors.lastname: Hanif
mesh_terms: D002648:Child; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D012763:Shigella flexneri / Q000201:enzymology* / Q000302:isolation & purification; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases