title: Predictors of improved overactive bladder symptoms after transvaginal mesh repair for the treatment of pelvic organ prolapse: predictors of improved OAB after POP repair.
abstract: OBJECTIVE
  The aim of this study was to identify the predictors of improved overactive bladder (OAB) symptoms after transvaginal mesh repair.
  
  
  METHODS
  Eighty women with pelvic organ prolapse (POP) stage II to IV reporting OAB symptoms were scheduled for transvaginal mesh procedures. Preoperative and postoperative assessments included a bladder diary, urodynamics, and a personal interview about urinary symptoms.
  
  
  RESULTS
  Sixty-three (78.8%) women experienced improvement of OAB symptoms (Improvement group), and 17 (21.2%) women remained unchanged or worsened (Persistence group) postoperatively. A univariate analysis of patients' characteristics showed no difference between two groups regarding parity, diabetes, hypertension, prolapse status, preoperative urodynamic parameters, and urinary symptoms (P > 0.05). However, the age (P = 0.042) and preoperative detrusor overactivity (DO) (P = 0.03) were two significant predictors of postoperative OAB improvement.
  
  
  CONCLUSIONS
  Women with POP may experience improvement of their OAB symptoms after transvaginal mesh repair. Both age and DO were two predictors in our univariate analysis, and the latter was the only significant predictor of symptom relief after adjusting age factor.
authors.affiliation: Graduate Institute of Medicine, Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Cheng-Yu
authors.initials: CY
authors.lastname: Long
authors.forename: Chun-Shuo
authors.initials: CS
authors.lastname: Hsu
authors.forename: Ming-Ping
authors.initials: MP
authors.lastname: Wu
authors.forename: Cheng-Min
authors.initials: CM
authors.lastname: Liu
authors.forename: Po-Hui
authors.initials: PH
authors.lastname: Chiang
authors.forename: Yung-Shun
authors.initials: YS
authors.lastname: Juan
authors.forename: Eing-Mei
authors.initials: EM
authors.lastname: Tsai
mesh_terms: D000367:Age Factors; D000368:Aged; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000150:complications* / Q000601:surgery*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013526:Surgical Mesh; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000453:epidemiology*