title: Comorbid major depression in obsessive-compulsive disorder patients.
abstract: Although major depressive disorder (MDD) has been consistently considered the most frequent complication of obsessive-compulsive disorder (OCD), little is known about the clinical characteristics of patients with both disorders. This study assessed 815 Brazilian OCD patients using a comprehensive psychiatric evaluation. Clinical and demographic variables, including OCD symptom dimensions, were compared among OCD patients with and without MDD. Our findings showed that prevalence rates of current MDD (32%) and lifetime MDD (67.5%) were similar for both sexes in this study. In addition, patients with comorbid MDD had higher severity scores of OCD symptoms. There was no preferential association of MDD with any particular OCD symptom dimension. This study supports the notion that depressed OCD patients present more severe general psychopathology.
authors.affiliation: University Hospital, Psychiatry Service, Universidade Federal da Bahia, Salvador, Brazil. lcq@ufba.br
authors.forename: Lucas C
authors.initials: LC
authors.lastname: Quarantini
authors.forename: Albina Rodrigues
authors.initials: AR
authors.lastname: Torres
authors.forename: Aline S
authors.initials: AS
authors.lastname: Sampaio
authors.forename: Victor
authors.initials: V
authors.lastname: Fossaluza
authors.forename: Maria Alice de
authors.initials: MA
authors.lastname: Mathis
authors.forename: Maria Conceição
authors.initials: MC
authors.lastname: do Rosário
authors.forename: Leonardo F
authors.initials: LF
authors.lastname: Fontenelle
authors.forename: Ygor A
authors.initials: YA
authors.lastname: Ferrão
authors.forename: Aristides Volpato
authors.initials: AV
authors.lastname: Cordioli
authors.forename: Katia
authors.initials: K
authors.lastname: Petribu
authors.forename: Ana G
authors.initials: AG
authors.lastname: Hounie
authors.forename: Eurípedes C
authors.initials: EC
authors.lastname: Miguel
authors.forename: Roseli G
authors.initials: RG
authors.lastname: Shavitt
authors.forename: Karestan C
authors.initials: KC
authors.lastname: Koenen
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D012720:Severity of Illness Index