title: Innovation and management of diabetic foot wounds.
abstract: Recent innovations in the field of wound healing have created numerous advanced therapies from which clinicians may now choose. The challenge for the reconstructive surgeon is to ensure that these adjunct technologies are used according to an evidence-based protocol to ensure optimal healing. Critical to successful outcomes is that new modes of therapy do not supplant, but are used in tandem with, core principles of wound management: establishing a correct diagnosis, ensuring a good local blood supply, debriding the wound to a clean base, correcting the biomechanical abnormality, and nurturing the wound until it shows signs of healing. Debridement should be performed as often as necessary until the wound is deemed clean and ready for reconstruction. Useful adjuncts in debridement include hydrotherapy and ultrasonic therapy. The majority of reconstructions are accomplished through simple techniques. If a wound is not meeting the expected healing trajectory, management adjuncts such as negative pressure wound therapy, growth factor, cultured skin, and hyperbaric oxygen can then reactivate or expedite the process toward achieving a healed wound.
authors.affiliation: Department of Plastic Surgery, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
authors.forename: Mark W
authors.initials: MW
authors.lastname: Clemens
authors.forename: Justin M
authors.initials: JM
authors.lastname: Broyles
authors.forename: Phi-Nga Jeannie
authors.initials: PN
authors.lastname: Le
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Attinger
mesh_terms: D017719:Diabetic Foot / Q000150:complications* / Q000601:surgery*; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D016038:Skin Transplantation; D013529:Surgical Wound Dehiscence / Q000209:etiology* / Q000628:therapy*; D014464:Ultrasonic Therapy / Q000379:methods; D014945:Wound Healing