title: Asymptomatic leukemic-cell infiltration of the pancreas: US findings.
abstract: Pancreatic infiltration of leukemic cells is a very rare manifestation at the onset of acute lymphoblastic leukemia (ALL) in childhood. Pancreatic enlargement in this situation is unusual and pancreatic involvement is often associated with biliary obstruction, cholestasis and pancreatitis. We report a 3-month-old girl who presented with asymptomatic leukemic infiltration of the pancreas, demonstrated by US with heterogeneous pancreatic enlargement associated with multiple hypoechogenic lesions, without cholestasis. Although these manifestations are rare, ALL should be considered a cause of pancreatic enlargement.
authors.affiliation: Department of Radiology, Hospital Nacional de Pediatria Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881 (1254), Buenos Aires, Argentina.
authors.forename: Laura
authors.initials: L
authors.lastname: Collado
authors.forename: Esteban
authors.initials: E
authors.lastname: Dardanelli
authors.forename: Sergio
authors.initials: S
authors.lastname: Sierre
authors.forename: Silvia
authors.initials: S
authors.lastname: Moguillansky
authors.forename: José
authors.initials: J
authors.lastname: Lipsich
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D017254:Leukemic Infiltration / Q000000981:diagnostic imaging* / Q000473:pathology*; D010179:Pancreas / Q000000981:diagnostic imaging* / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D014463:Ultrasonography / Q000379:methods*