title: In vitro evaluation of surface based non-invasive breast cancer screening with digital image based Elasto tomography (DIET).
abstract: Digital Image-based Elasto Tomography (DIET) is a non-invasive breast cancer screening modality that induces vibrations into a breast and images its surface motion with digital cameras. Disturbances in the motion are caused by areas of higher stiffness within the breast, potentially cancerous tumors. A concept is presented to detect the angular location of a tumor by analyzing the phase delay of the vibrations on the surface. The approach is verified experimentally on silicone phantom breasts with stiffer inclusions ranging from 0-32 mm. A strong signal differentiating healthy and cancerous phantoms can be seen at the second modal frequency of the breast, clearly detecting a 10 mm tumor. This approach offers great potential for this low cost and accessible breast cancer screening, as an adjunct to existing modalities.
authors.affiliation: Department of Mechanical Engineering, University of Canterbury, Christchurch 8140, New Zealand. thomas.lotz@canterbury.ac.zn
authors.forename: Thomas
authors.initials: T
authors.lastname: Lotz
authors.forename: Paul D
authors.initials: PD
authors.lastname: Simpson
authors.forename: Daniel
authors.initials: D
authors.lastname: Stocker
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Hann
authors.forename: J Geoffrey
authors.initials: JG
authors.lastname: Chase
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D003952:Diagnostic Imaging / Q000379:methods; D055088:Early Detection of Cancer / Q000379:methods; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D066298:In Vitro Techniques; D009038:Motion; D019047:Phantoms, Imaging; D012828:Silicones; D013499:Surface Properties; D014054:Tomography / Q000379:methods*
chemical_list: D012828:Silicones