title: Diabetic gastroparesis and its impact on glycemia.
abstract: Diabetes is the most common cause of gastroparesis and it is now recognized that the relationship between gastric emptying and glycemia is complex and intertwined. Postprandial blood glucose levels influence, and are influenced by, the rate of gastric emptying, highlighting the difficulty in determining which is the cause and which is the effect. Novel diagnostic techniques and therapeutic strategies have been developed for the management of diabetic gastroparesis. This article highlights recent advances in knowledge about diabetic gastroparesis, with an emphasis on the inter-relationships between disordered gastric motor function on glycemia and vice versa, as well as therapeutic strategies for optimizing glycemic control using modulation of gastric emptying.
authors.affiliation: Discipline of Medicine, Royal Adelaide Hospital, University of Adelaide, South Australia 5000, Australia.
authors.forename: Jessica
authors.initials: J
authors.lastname: Chang
authors.forename: Christopher K
authors.initials: CK
authors.lastname: Rayner
authors.forename: Karen L
authors.initials: KL
authors.lastname: Jones
authors.forename: Michael
authors.initials: M
authors.lastname: Horowitz
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000503:physiopathology; D003929:Diabetic Neuropathies / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D005746:Gastric Emptying / Q000502:physiology; D018589:Gastroparesis / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology / Q000628:therapy; D007022:Hypotension / Q000209:etiology / Q000628:therapy; D019518:Postprandial Period / Q000502:physiology
chemical_list: D001786:Blood Glucose