title: Histopathologic characteristics of the transitional stage of measles-associated appendicitis: case report and review of the literature.
abstract: From 2006 to 2009, Switzerland experienced the highest measles incidence rate in Central and Western Europe. This increased occurrence of measles cases is mainly due to insufficient vaccination of the Swiss population over a period of many years. Acute appendicitis is a rare complication of measles infection. To date, 25 cases of measles-associated appendicitis have been documented in the English literature. Sixteen (64.0%) of the 25 patients had developed appendicitis in the prodromal stage of measles before skin rash appeared. This article describes the unusual histopathologic findings of measles-associated appendicitis in a 19-year-old non-measles-vaccinated man in the transitional phase from prodromal to full-blown disease and provides a comprehensive review of the literature.
authors.affiliation: Institute of Pathology, Kantonsspital Baden AG, 5404 Baden, Switzerland.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Stadlmann
authors.forename: Daniela M
authors.initials: DM
authors.lastname: Lenggenhager
authors.forename: Venancio A
authors.initials: VA
authors.lastname: Alves
authors.forename: Suely
authors.initials: S
authors.lastname: Nonogaki
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Kocher
authors.forename: Hans-Ruedi
authors.initials: HR
authors.lastname: Schmid
authors.forename: Gad
authors.initials: G
authors.lastname: Singer
mesh_terms: D000208:Acute Disease; D001064:Appendicitis / Q000473:pathology* / Q000601:surgery / Q000821:virology; D006801:Humans; D008297:Male; D008457:Measles / Q000150:complications / Q000473:pathology*; D008459:Measles virus / Q000235:genetics / Q000302:isolation & purification; D012367:RNA, Viral / Q000032:analysis; D055815:Young Adult
chemical_list: D012367:RNA, Viral