title: Grand challenge commentary: Chemical transdifferentiation and regenerative medicine.
abstract: The ability to alter cell identity with small molecules represents a powerful approach to restore biological function lost because of cellular deficiency. Developing this capability through advances in chemical biology could have an enormous impact on human health.
authors.affiliation: Chemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. bwagner@broadinstitute.org
authors.forename: Bridget K
authors.initials: BK
authors.lastname: Wagner
mesh_terms: D000818:Animals; D054338:Cell Transdifferentiation / Q000187:drug effects* / Q000502:physiology; D002621:Chemistry / Q000639:trends*; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D020127:Recovery of Function; D044968:Regenerative Medicine / Q000639:trends*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology; D054852:Small Molecule Libraries
chemical_list: D054852:Small Molecule Libraries