title: Getting personal: considering variable interindividual responsiveness to dietary lipid-lowering therapies.
abstract: OBJECTIVE
  There is substantial interindividual variation in the response of blood lipids to dietary therapies. The purpose of this review is to highlight recent developments in identifying patient-specific factors that contribute to the significant heterogeneity of responsiveness in lipids to dietary changes and consumption of dietary bioactive compounds.
  
  
  RESULTS
  Recent findings suggest that a variety of patient-specific physiological, pathological, environmental, and genetic factors influence the effectiveness of dietary lipid-lowering therapies.
  
  
  CONCLUSIONS
  Although genetic markers of responsiveness will revolutionize future personalized nutrition therapies, current research priorities should emphasize the identification of readily accessible metabolic biomarkers of responsiveness in patient subgroups.
authors.affiliation: Department of Exercise & Nutrition Sciences, University at Buffalo, Buffalo, NY, USA. t_rideout@umanitoba.ca
authors.forename: Todd C
authors.initials: TC
authors.lastname: Rideout
mesh_terms: D004035:Diet Therapy; D006801:Humans; D008055:Lipids / Q000097:blood*
chemical_list: D008055:Lipids