title: Gestational diabetes mellitus: taking it to heart.
abstract: Globally, cardiovascular disease (CVD) accounts for 1/3 of all deaths to women. While much research identifies the increased risk in CVD associated with pre-diabetes measurements, there is growing interest in the role of gestational diabetes mellitus (GDM)-a condition of glucose intolerance diagnosed during pregnancy-as a potential CVD risk factor. This article reviews existing evidence supporting this association, particularly regarding GDM and type 2 diabetes, hypertension, atherogenic dyslipedmia, and CVD events. Finally, it discusses the research and clinical ramifications of identifying GDM as a CVD risk factor, highlighting the need for more rigorous research on this topic.
authors.affiliation: Program in Nutrition and Health Sciences, Emory University, Atlanta, GA, USA. jmarcin@emory.edu
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Marcinkevage
authors.forename: K M Venkat
authors.initials: KM
authors.lastname: Narayan
mesh_terms: D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D016640:Diabetes, Gestational / Q000097:blood / Q000453:epidemiology; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D011247:Pregnancy; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors
chemical_list: D015415:Biomarkers