title: Room temperature ionic liquid-mediated molecularly imprinted polymer monolith for the selective recognition of quinolones in pork samples.
abstract: A novel molecularly imprinted polymer monolith was prepared by the room temperature ionic liquid-mediated in situ molecular imprinting technique, using norfloxacin (NOR) as the template, methacrylic acid as the functional monomer, ethylene glycol dimethacrylate as the cross-linker. The optimal synthesis conditions and recognition properties of NOR-imprinted monolithic column were investigated. The results indicated that the imprinted monoliths exhibited good ability of selective recognition against the template and its structural analog. Using the fabricated material as solid-phase extraction sorbent, a sample pre-treatment procedure of molecularly imprinted solid-phase extraction coupling with HPLC was developed for determination of trace quinolone residues in animal tissues samples. The recoveries ranging from 78.16 to 93.50% for eight quinolones antibiotics such as marbofloxacin, NOR, ciprofloxacin, danofloxacin, difloxacin, oxolinic acid, flumequine and enrofloxacin were obtained.
authors.affiliation: Department of Chemistry, Nankai University, Tianjin, PR China.
authors.forename: Xiangli
authors.initials: X
authors.lastname: Sun
authors.forename: Jia
authors.initials: J
authors.lastname: He
authors.forename: Guorui
authors.initials: G
authors.lastname: Cai
authors.forename: Anqing
authors.initials: A
authors.lastname: Lin
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zheng
authors.forename: Xuan
authors.initials: X
authors.lastname: Liu
authors.forename: Langxing
authors.initials: L
authors.lastname: Chen
authors.forename: Xiwen
authors.initials: X
authors.lastname: He
authors.forename: Yukui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D007477:Ions; D008461:Meat Products / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D011108:Polymers / Q000737:chemistry*; D015363:Quinolones / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*; D013552:Swine; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D007477:Ions; D011108:Polymers; D015363:Quinolones