title: [Progress of molecular imaging research on the use of RNA interference in malignant tumors].
abstract: RNA interference (RNAi) is applied in the gene therapy of malignant tumors as an effective technique to degrade its homologous mRNA specifically. This technique has been developed quickly in broad prospects. Molecular imaging plays an important role both in gene imaging and in molecular signal transduction. It is used as a direct approach to study the onset and development of disease. The technique of RNAi can be used for preparing molecular probes, for making earlier and specific diagnosis, and for targeted gene therapy of malignant tumors.
authors.affiliation: Clinical Seven-year Program, Chongqing Medical University, Chongqing 400016, China.
authors.forename: Mengya
authors.initials: M
authors.lastname: Li
authors.forename: Ming
authors.initials: M
authors.lastname: Wen
mesh_terms: D000818:Animals; D015316:Genetic Therapy; D006801:Humans; D057054:Molecular Imaging / Q000379:methods* / Q000639:trends*; D015336:Molecular Probe Techniques; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D034622:RNA Interference