title: A role for myokines in muscle-bone interactions.
abstract: This review presents the hypothesis that muscle is a source of secreted factors (myokines) that can influence bone mass in both positive and negative ways. Growth factor secretion by muscle may therefore be one pathway through which mechanical signals are transduced biologically.
authors.affiliation: Department of Cellular Biology & Anatomy, Institute of Molecular Medicine and Genetics, and Department of Orthopaedic Surgery, Medical College of Georgia, Augusta, GA 30912, USA. mhamrick@mail.mcg.edu
authors.forename: Mark W
authors.initials: MW
authors.lastname: Hamrick
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D019899:Paracrine Communication; D015398:Signal Transduction
chemical_list: D016207:Cytokines; D036341:Intercellular Signaling Peptides and Proteins