title: Multimodal imaging reveals the role of γ activity in eating-reflex seizures.
abstract: In reflex epilepsies, alteration of γ oscillations may mediate transition between interictal and ictal states. Here, we explored a patient having seizures triggered by syrup intake. From intracranial electroencephalography combined with functional MRI, the overlap of the gustatory cortex and of the preictal and ictal onset zones, as defined by early gamma changes, motivated the successful resective surgery of the middle short gyrus of the right insula. This case provides a rare demonstration from human gamma activity that the route to seizure may be supported by the interplay between physiological and epileptogenic networks.
authors.affiliation: INSERM, U836, Grenoble Institute of Neuroscience, Grenoble, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Blauwblomme
authors.forename: Philippe
authors.initials: P
authors.lastname: Kahane
authors.forename: Lorella
authors.initials: L
authors.lastname: Minotti
authors.forename: Frédéric
authors.initials: F
authors.lastname: Grouiller
authors.forename: Alexandre
authors.initials: A
authors.lastname: Krainik
authors.forename: Laurent
authors.initials: L
authors.lastname: Vercueil
authors.forename: Stéphan
authors.initials: S
authors.lastname: Chabardès
authors.forename: Dominique
authors.initials: D
authors.lastname: Hoffmann
authors.forename: Olivier
authors.initials: O
authors.lastname: David
mesh_terms: D001931:Brain Mapping; D058256:Brain Waves / Q000502:physiology*; D002540:Cerebral Cortex / Q000503:physiopathology / Q000601:surgery; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography; D020195:Epilepsy, Reflex / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology / Q000601:surgery; D020786:Hemangioma, Cavernous, Central Nervous System / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009415:Nerve Net / Q000503:physiopathology / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D055815:Young Adult