title: Role of tyramine synthesis by food-borne Enterococcus durans in adaptation to the gastrointestinal tract environment.
abstract: Biogenic amines in food constitute a human health risk. Here we report that tyramine-producing Enterococcus durans strain IPLA655 (from cheese) was able to produce tyramine under conditions simulating transit through the gastrointestinal tract. Activation of the tyramine biosynthetic pathway contributed to binding and immunomodulation of enterocytes.
authors.affiliation: Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Fernández de Palencia
authors.forename: Maria
authors.initials: M
authors.lastname: Fernández
authors.forename: Maria Luz
authors.initials: ML
authors.lastname: Mohedano
authors.forename: Victor
authors.initials: V
authors.lastname: Ladero
authors.forename: Cristina
authors.initials: C
authors.lastname: Quevedo
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Alvarez
authors.forename: Paloma
authors.initials: P
authors.lastname: López
mesh_terms: D000222:Adaptation, Physiological; D001422:Bacterial Adhesion; D002460:Cell Line; D002611:Cheese / Q000382:microbiology*; D016983:Enterococcus / Q000378:metabolism / Q000502:physiology*; D020895:Enterocytes / Q000276:immunology / Q000382:microbiology; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D014439:Tyramine / Q000096:biosynthesis*
chemical_list: D014439:Tyramine