title: An analytic model of neutron ambient dose equivalent and equivalent dose for proton radiotherapy.
abstract: Stray neutrons generated in passively scattered proton therapy are of concern because they increase the risk that a patient will develop a second cancer. Several investigations characterized stray neutrons in proton therapy using experimental measurements and Monte Carlo simulations, but capabilities of analytical methods to predict neutron exposures are less well developed. The goal of this study was to develop a new analytical model to calculate neutron ambient dose equivalent in air and equivalent dose in phantom based on Monte Carlo modeling of a passively scattered proton therapy unit. The accuracy of the new analytical model is superior to a previous analytical model and comparable to the accuracy of typical Monte Carlo simulations and measurements. Predictions from the new analytical model agreed reasonably well with corresponding values predicted by a Monte Carlo code using an anthropomorphic phantom.
authors.affiliation: Graduate School of Biomedical Sciences, The University of Texas at Houston, Houston, TX 77030, USA.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Angélica
authors.initials: A
authors.lastname: Pérez-Andújar
authors.forename: Jonas D
authors.initials: JD
authors.lastname: Fontenot
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Taddei
authors.forename: Wayne D
authors.initials: WD
authors.lastname: Newhauser
mesh_terms: D000042:Absorption; D000388:Air; D006801:Humans; D008297:Male; D008954:Models, Biological; D009010:Monte Carlo Method; D009502:Neutrons / Q000009:adverse effects*; D019047:Phantoms, Imaging; D061766:Proton Therapy; D011829:Radiation Dosage; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D011522:Protons
chemical_list: D011522:Protons