title: Brain abscess: an overview.
abstract: Intracranial abscess is a formidable entity. Despite the advent of newer antibiotics and surgical strategies, the overall outcome and quality of life issues in brain abscess patients still remain a continuous challenge for the neurosurgical community. It is a direct interplay between the virulence of the offending microorganism and the immune response of the host. An analysis of our experience in the 289 cases of surgically treated pyogenic brain abscess is presented along with an overview of intra-cranial abscess of varied etiology and in different locations. The etiology, pathogenesis, radiological advances and treatment modalities of brain abscess are discussed in light of current literature.
authors.affiliation: Department of Neurosurgery, Seth Gordhandas Sunderdas Medical College and King Edward VII Memorial Hospital, Parel, Mumbai, India. dmuzumdar@hotmail.com
authors.forename: Dattatraya
authors.initials: D
authors.lastname: Muzumdar
authors.forename: Sukhdeep
authors.initials: S
authors.lastname: Jhawar
authors.forename: A
authors.initials: A
authors.lastname: Goel
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D019635:Neurosurgical Procedures
chemical_list: D000900:Anti-Bacterial Agents; D000927:Anticonvulsants