title: [Effect of plasmaslyte A on the liver function of patients undergoing cardiac surgery with extracorporeal circulation].
abstract: OBJECTIVE
  To observe the effect of plasmaslyte A on the liver function of patients receiving cardiac surgery with extracorporeal circulation.
  
  
  METHODS
  Sixty patients scheduled for cardiac surgery were randomized to receive plasmaslyte A (group P, n=30) and ringer lactate solution (group R, n=30). The two agents were used in priming heart-lung machine and intra- and postoperative crystal solution. All the patients were examined for the levels of AST, ALT and Lac the day before and at 2 h and 1, 3 and 7 days after the surgery. The time of extubation and length of stay at the ICU were record.
  
  
  RESULTS
  The levels of ALT, AST and Lac in group P were significantly lower than those in group R (P<0.05), and the duration of intubation and stay at the ICU was shorter in group P (P<0.05).
  
  
  CONCLUSIONS
  Plasmaslyte A can markedly reduce the level of AST, ALT and Lac and protect the liver function of patients undergoing cardiac surgery with extracorporeal circulation.
authors.affiliation: Department of Anesthesiology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan 528403, China. lbf8@msn.com
authors.forename: Bin-fei
authors.initials: BF
authors.lastname: Li
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Xie
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Zhang
authors.forename: Zhou
authors.initials: Z
authors.lastname: Cheng
authors.forename: Xiao-zu
authors.initials: XZ
authors.lastname: Liao
authors.forename: Wei-kang
authors.initials: WK
authors.lastname: Luo
mesh_terms: D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007552:Isotonic Solutions / Q000494:pharmacology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D000077325:Ringer's Lactate
chemical_list: D007552:Isotonic Solutions; D000077325:Ringer's Lactate