title: Autopsy and histological analysis of the transgenic mouse.
abstract: Over the past decades, transgenic and knock-out mouse models have become common use in research laboratories. Detailed phenotypic characterization of such models is essential for understanding basic mechanisms of normal physiology and disease. Hereto, pathological examination is a very helpful tool. This chapter describes detailed procedures to perform autopsy and immuno-histological analysis of mice.
authors.affiliation: Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. m.gijbels@gen.unimaas.nl
authors.forename: Marion J J
authors.initials: MJ
authors.lastname: Gijbels
authors.forename: Menno P J
authors.initials: MP
authors.lastname: de Winther
mesh_terms: D000818:Animals; D001344:Autopsy / Q000379:methods*; D007150:Immunohistochemistry / Q000379:methods*; D051379:Mice; D008822:Mice, Transgenic