title: Cell behaviour on bioactive polymeric coatings.
abstract: Researchers are testing different treatments to induce modifications in both chemical composition and topography of implant surface, with the aim to ameliorate bone-to-implant contacts and hence improve osseointegration processes and biomechanical properties in the short and long-term. Aim of the present research was the evaluation of MG63 osteoblast-like cells behaviour on polymeric coatings, electrosynthesized on titanium substrates, differently modified in order to improve implant performances both in terms of osseointegration and infection prevention. Cell viability data and scanning electron microscopy morphological observations were consistent with a good compatibility of modified electrosynthesized coatings and suggest the use of this procedure to produce new bioactive titanium coatings for implant surgery.
authors.affiliation: Sezione di Istologia ed Embriologia Umana, Dipartimento di Patologia Molecolare e Terapie Innovative. m.mattioli@univpm.it
authors.forename: Monica
authors.initials: M
authors.lastname: Mattioli-Belmonte
authors.forename: Monia
authors.initials: M
authors.lastname: Orciani
authors.forename: Concetta
authors.initials: C
authors.lastname: Ferretti
authors.forename: Giovanna
authors.initials: G
authors.lastname: Orsini
authors.forename: Elvira
authors.initials: E
authors.lastname: De Giglio
authors.forename: Roberto
authors.initials: R
authors.lastname: Di Primio
mesh_terms: D002460:Cell Line; D048430:Cell Shape / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D020100:Hydrogels / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D008855:Microscopy, Electron, Scanning / Q000379:methods; D016348:Osseointegration / Q000187:drug effects / Q000502:physiology*; D010006:Osteoblasts / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure; D056951:Photoelectron Spectroscopy / Q000379:methods; D011108:Polymers / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D019736:Prostheses and Implants / Q000648:ultrastructure*; D014025:Titanium / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D020099:Coated Materials, Biocompatible; D020100:Hydrogels; D011108:Polymers; D014025:Titanium