title: Vascular disorders in neuro-ophthalmology.
abstract: OBJECTIVE
  The aim is to briefly discuss the currently controversial management of nonarteritic anterior ischemic optic neuropathy (NA-AION) and central retinal artery occlusion (CRAO).
  
  
  RESULTS
  The role of systemic corticosteroid therapy and aspirin in NA-AION and of thrombolysis in CRAO is discussed.
  
  
  CONCLUSIONS
  NA-AION is a major cause of seriously impaired vision. A recent large prospective study has shown that systemic corticosteroid resulted in a significantly higher probability of improvement in visual acuity (P = 0.001) and visual fields (P = 0.005), compared to an untreated group. In CRAO, the latest prospective study has shown that thrombolytic therapy not only has no beneficial effect but also is harmful.
authors.affiliation: Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa, USA. sohan-hayreh@uiowa.edu
authors.forename: Sohan Singh
authors.initials: SS
authors.lastname: Hayreh
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D006801:Humans; D009885:Ophthalmology; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy / Q000628:therapy*; D015356:Retinal Artery Occlusion / Q000150:complications / Q000628:therapy; D014794:Visual Fields
chemical_list: D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D001241:Aspirin