title: Subcutaneous phaeohyphomycosis caused by Cladophialophora boppii.
abstract: Subcutaneous phaeohyphomycosis is an infection of the skin and subcutaneous tissue, caused by dematiaceous fungi. An adult male presented with a history of multiple reddish nodules over the face and hands. Histopathological examination of the skin biopsies showed a dense granulomatous infiltrate of macrophages, containing intracytoplasmic basophilic bodies throughout the dermis. Gomori methenamine-silver stained sections revealed yeast cells within macrophages. Multiple cultures on Sabouraud's dextrose agar grew Cladophialophora boppii. The patient was treated with oral itraconazole for a year and the response monitored with dermal ultrasound. This is the first case report of subcutaneous phaeohyphomycosis caused by Cl. boppii in India.
authors.affiliation: Department of Dermatology, T.N. Medical College and B.Y.L. Nair Ch. Hospital, Mumbai Central, Mumbai, India.
authors.forename: Rickson R
authors.initials: RR
authors.lastname: Pereira
authors.forename: Chitra S
authors.initials: CS
authors.lastname: Nayak
authors.forename: Sunita D
authors.initials: SD
authors.lastname: Deshpande
authors.forename: Kalpana D
authors.initials: KD
authors.lastname: Bhatt
authors.forename: Swapna S
authors.initials: SS
authors.lastname: Khatu
authors.forename: Rachita S
authors.initials: RS
authors.lastname: Dhurat
mesh_terms: D001203:Ascomycota / Q000472:pathogenicity*; D003881:Dermatomycoses / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D040521:Subcutaneous Tissue / Q000000981:diagnostic imaging* / Q000187:drug effects / Q000382:microbiology*; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D017964:Itraconazole