title: [Correction of tissue hypoxia with reamberin in severe forms of acute intoxication with neurotropic poisons].
abstract: Examination and treatment of 66 patients severely intoxicated with neurotropic poisons showed that inclusion of reamberin in combined therapy decreased the degree of tissue hypoxia as apparent from increased oxygen consumption, oxygen utilization index, and arteriovenous oxygen difference. This in turn accelerated recovery of antioxidant protection and lowered activity of lipid peroxidation. The use of reamberin for the treatment of acute neurotropic intoxication improves clinical conditions of the patients by decreasing duration of the comatose state, requirement for intensive therapy, and lethality.
authors.forename: G A
authors.initials: GA
authors.lastname: Livanov
authors.forename: B V
authors.initials: BV
authors.lastname: Batotsyrenov
authors.forename: A N
authors.initials: AN
authors.lastname: Lodiagin
authors.forename: Kh V
authors.initials: KhV
authors.lastname: Batotsyrenova
authors.forename: G V
authors.initials: GV
authors.lastname: Shestova
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D003128:Coma / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D020258:Neurotoxicity Syndromes / Q000150:complications / Q000188:drug therapy*; D013386:Succinates / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; C549374:Reamberin; D013386:Succinates; D008536:Meglumine