title: Anomalous origin of the left coronary artery from the pulmonary artery in Alagille syndrome.
abstract: Alagille syndrome is a dominantly inherited multisystem disorder involving multiple organs including the liver, heart, eyes, face, and skeleton. Congenital heart defects, the majority of which are right-sided, contribute significantly to the mortality of these patients. We report a patient with Alagille syndrome who presented with mitral valve regurgitation requiring valvuloplasty and subsequent mitral valve replacement. The patient was ultimately diagnosed with anomalous origin of the left coronary artery from the pulmonary artery and underwent successful reimplantation.
authors.affiliation: Division of Pediatric Critical Care, University of Utah School of Medicine, Salt Lake City, UT 84113, USA. tara.lemoine@hsc.utah.edu
authors.forename: Tara J
authors.initials: TJ
authors.lastname: Lemoine
authors.forename: Aditya K
authors.initials: AK
authors.lastname: Kaza
authors.forename: Robert
authors.initials: R
authors.lastname: Gray
authors.forename: Ronald W
authors.initials: RW
authors.lastname: Day
authors.forename: Lloyd Y
authors.initials: LY
authors.lastname: Tani
authors.forename: William Bradley
authors.initials: WB
authors.lastname: Poss
mesh_terms: D016738:Alagille Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D002404:Catheterization; D003330:Coronary Vessel Anomalies / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007223:Infant; D008944:Mitral Valve Insufficiency / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000601:surgery; D012092:Replantation; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures