title: Molecular diagnosis of nonaneurysmal infectious aortitis.
abstract: We report a 79-year-old patient who presented with a fever and abdominal pain. The patient was initially thought to have a retroperitoneal fibrosis or inflammatory abdominal aortitis in a normal-sized caliber aorta. Broad-range polymerase chain reaction (PCR) and DNA sequencing revealed the presence of Enterobacter. We finally diagnosed nonaneurysmal infectious aortitis, and we performed a successful surgical resection. Establishing a diagnosis of aortic infection before formation of an aneurysm is difficult. The molecular diagnostic technique was particularly useful in specifying the microbial species and diagnosis.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Mie, Japan. skanemitsu70@clin.medic.mie-u.ac.jp
authors.forename: Shinji
authors.initials: S
authors.lastname: Kanemitsu
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Shimono
authors.forename: Akiko
authors.initials: A
authors.lastname: Nakamura
authors.forename: Kiyohito
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Wada
authors.forename: Hideto
authors.initials: H
authors.lastname: Shimpo
mesh_terms: D015746:Abdominal Pain / Q000382:microbiology; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001025:Aortitis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D001027:Aortography / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D004269:DNA, Bacterial / Q000302:isolation & purification; D004754:Enterobacter / Q000235:genetics / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D005334:Fever / Q000382:microbiology; D006801:Humans; D008297:Male; D025202:Molecular Diagnostic Techniques; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D021521:Ribotyping; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial