title: LPV control of glucose for Diabetes type I.
abstract: This paper considers the problem of automatically controlling the glucose level in a Diabetes type I patient. Three issues have been considered: model uncertainty, time-varying/nonlinear phenomena and controller implementation. To that end, the dynamical model of the insulin/glucose relation is framed as a Linear Parameter Varying system and a controller is designed based on it. In addition, this framework allows not only a better performance than other classical methods, but also provides stability and performance guarantees. Design computations are based on convex Linear Matrix Inequality (LMI) optimization. Implementation is based on a low order controller whose dynamics adapts according to the glucose levels measured in real-time.
authors.affiliation: Centro de Sistemas y Control, Department of Physics & Mathematics Buenos Aires Institute of Technology (ITBA), Argentina. rsanchez@itba.edu.ar
authors.forename: R S
authors.initials: RS
authors.lastname: Sánchez Peña
authors.forename: A S
authors.initials: AS
authors.lastname: Ghersin
mesh_terms: D003198:Computer Simulation; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy* / Q000378:metabolism*; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000008:administration & dosage*; D016014:Linear Models; D008954:Models, Biological
chemical_list: D007328:Insulin; D005947:Glucose