title: Effectiveness of haemophilus influenzae type B conjugate vaccine for prevention of meningitis in Senegal.
abstract: A total of 24 cases of hospitalized, laboratory-confirmed Haemophilus influenzae type b (Hib) meningitis were identified through a regional pediatric bacterial meningitis surveillance system. Each case was matched by age and residence to 4 neighborhood controls. The adjusted vaccine effectiveness for ≥ 2 doses was 95.8% (95% confidence interval, 67.9%-99.4%). Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal.
authors.affiliation: Vaccine Access and Delivery, PATH, Seattle, WA, USA. jfleming@path.org
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Fleming
authors.forename: Yakou
authors.initials: Y
authors.lastname: Dieye
authors.forename: Ousseynou
authors.initials: O
authors.lastname: Ba
authors.forename: Boniface
authors.initials: B
authors.lastname: Mutombo wa Mutombo
authors.forename: Ndiouga
authors.initials: N
authors.lastname: Diallo
authors.forename: Pape Coumba
authors.initials: PC
authors.lastname: Faye
authors.forename: Mamadou
authors.initials: M
authors.lastname: Ba
authors.forename: Moussa Fafa
authors.initials: MF
authors.lastname: Cisse
authors.forename: Aissatou Gaye
authors.initials: AG
authors.lastname: Diallo
authors.forename: Mady
authors.initials: M
authors.lastname: Ba
authors.forename: Mary P E
authors.initials: MP
authors.lastname: Slack
authors.forename: Noel S
authors.initials: NS
authors.lastname: Weiss
mesh_terms: D005260:Female; D018073:Haemophilus Vaccines / Q000008:administration & dosage / Q000276:immunology*; D019741:Haemophilus influenzae type b / Q000276:immunology*; D006302:Health Services Research; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D012675:Senegal / Q000453:epidemiology; D014611:Vaccination / Q000706:statistics & numerical data; D018074:Vaccines, Conjugate / Q000008:administration & dosage / Q000276:immunology
chemical_list: D018073:Haemophilus Vaccines; D018074:Vaccines, Conjugate