title: Evidence of a recombinant wild-type human astrovirus strain from a Kenyan child with gastroenteritis.
abstract: A human astrovirus (HAstV) strain from Kenya was characterized by nucleotide sequence analysis. Sequences from open reading frame 1a (ORF1a) clustered with genotype 6/7, those from ORF1b clustered with genotype 3, and those from ORF2 clustered with genotype 2. A recombination point in the ORF1b-ORF2 junction was identified, with a second possible recombination point within the ORF1a region.
authors.affiliation: Department of Medical Virology, Faculty of Health Sciences, University of Pretoria/National Health Laboratory Service, P.O. Box 2034, Pretoria 0001, South Africa.
authors.forename: Marianne
authors.initials: M
authors.lastname: Wolfaardt
authors.forename: Nicholas M
authors.initials: NM
authors.lastname: Kiulia
authors.forename: Jason M
authors.initials: JM
authors.lastname: Mwenda
authors.forename: Maureen B
authors.initials: MB
authors.lastname: Taylor
mesh_terms: D019350:Astroviridae Infections / Q000175:diagnosis* / Q000821:virology; D002648:Child; D016000:Cluster Analysis; D005759:Gastroenteritis / Q000175:diagnosis* / Q000821:virology*; D005838:Genotype; D006801:Humans; D007630:Kenya; D001257:Mamastrovirus / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral