title: Early detection of disease-oriented state from hyperspectral tongue images with principal component analysis and vector rotation.
abstract: In this article, we propose an effective colorprocessing algorithm to analyze the hyperspectral image of the tongue and its application to preventive medicine by the concept of Japanese traditional herbal medicine (Kampo medicine). Kampo medicine contains a number of concepts useful for preventive medicine such as "Mibyou" - disease-oriented state - signs of abnormalities. Hyperspectral images of the tongue were taken with the system with an integrating sphere, and tongue area without coating was eliminated automatically. Then, spectral information of the tongue area without coating was analyzed by principal component analysis, and the component vector best representing the clinical symptom was found by rotating the vector on a plane spanned by two arbitrary principal component vectors.
authors.affiliation: Department of Japanese-Oriental Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, 260-8670, JAPAN. may-s@umin.net
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Norimichi
authors.initials: N
authors.lastname: Tsumura
authors.forename: Keiko
authors.initials: K
authors.lastname: Ogawa-Ochiai
authors.forename: Toshiya
authors.initials: T
authors.lastname: Nakaguchi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kasahara
authors.forename: Takao
authors.initials: T
authors.lastname: Namiki
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000328:Adult; D000465:Algorithms; D000740:Anemia / Q000175:diagnosis; D001331:Automation; D005145:Face; D005260:Female; D006801:Humans; D007564:Japan; D008027:Light; D008297:Male; D008519:Medicine, Traditional; D008875:Middle Aged; D025341:Principal Component Analysis; D013315:Stress, Psychological / Q000175:diagnosis; D014059:Tongue / Q000033:anatomy & histology / Q000473:pathology*