title: Design and an efficient synthesis of natural product-based cyclopenta[b]pyran derivatives with potential bioactivity.
abstract: A series of 4-aryl-cyclopenta[b]pyran derivatives, designed based on natural product scaffold, were synthesized efficiently via multi-component reaction under solvent-free and catalyst-free conditions. This chemistry provides a new compound library with potential activity for biomedical screening.
authors.affiliation: School of Chemistry and Chemical Engineering, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou, Jiangsu 221116, PR China.
authors.forename: Changsheng
authors.initials: C
authors.lastname: Yao
authors.forename: Bei
authors.initials: B
authors.lastname: Jiang
authors.forename: Tuanjie
authors.initials: T
authors.lastname: Li
authors.forename: Bingbin
authors.initials: B
authors.lastname: Qin
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Feng
authors.forename: Honghong
authors.initials: H
authors.lastname: Zhang
authors.forename: Cuihua
authors.initials: C
authors.lastname: Wang
authors.forename: Shujiang
authors.initials: S
authors.lastname: Tu
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D018360:Crystallography, X-Ray; D015195:Drug Design; D008968:Molecular Conformation; D011714:Pyrans / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D012997:Solvents / Q000737:chemistry; D013696:Temperature
chemical_list: D001688:Biological Products; D011714:Pyrans; D012997:Solvents