title: Sarcoid-like reaction mimics progression of disease after induction chemotherapy for lung cancer.
abstract: The use of 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) for staging nonsmall cell lung cancer is widely recognized, whereas the value of fluorodeoxyglucose-positron emission tomography imaging in the evaluation of response to induction chemotherapy is still controversial. We describe a case of a 57-year-old man who had a sarcoid-like reaction develop during induction chemotherapy for a pathologically proven N2 lung cancer. Re-evaluation of the nodal status using fluorodeoxyglucose-positron emission tomography showed false-positive accumulation in the mediastinal and hilar lymph nodes, which led us to suspect lung cancer progression after induction chemotherapy.
authors.affiliation: Department of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan. chida-ths@umin.ac.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Chida
authors.forename: Takashi
authors.initials: T
authors.lastname: Inoue
authors.forename: Koichi
authors.initials: K
authors.lastname: Honma
authors.forename: Koji
authors.initials: K
authors.lastname: Murakami
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000601:surgery*; D003937:Diagnosis, Differential; D018450:Disease Progression; D019160:Endosonography; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D011013:Pneumonectomy; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18