title: Self-report and laboratory measures of impulsivity in patients with schizophrenia or schizoaffective disorder and healthy controls.
abstract: This study examined self-reported impulsivity and aggression and performance on the stop-signal task in patients with schizophrenia or schizoaffective disorder and healthy volunteers. Compared to controls, patients had higher scores on interview and questionnaire measures of impulsivity and aggression and showed increased stop-signal reaction time and greater response variability. These findings are consistent with a specific impairment in response inhibition in schizophrenia.
authors.affiliation: Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA. nolan@nki.rfmh.org
authors.forename: Karen A
authors.initials: KA
authors.lastname: Nolan
authors.forename: Debra
authors.initials: D
authors.lastname: D'Angelo
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Hoptman
mesh_terms: D000328:Adult; D000374:Aggression; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000175:diagnosis* / Q000209:etiology; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D011618:Psychotic Disorders / Q000150:complications; D011930:Reaction Time / Q000502:physiology*; D012559:Schizophrenia / Q000150:complications; D057566:Self Report; D017603:Signal Detection, Psychological / Q000502:physiology; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires