title: [Comparison between conventional 4 L polyethylene glycol and combination of 2 L polyethylene glycol and sodium phosphate solution as colonoscopy preparation].
abstract: OBJECTIVE
  Effective bowel preparation is essential for accurate diagnosis of colon disease. We investigated efficacy and safety of 2 L polyethylene glycol (PEG) solution with 90 mL sodium phosphate (NaP) solution compared with 4 L PEG method.
  
  
  METHODS
  Between August 2009 and April 2010, 526 patients were enrolled who visited Seoul National University Bundang Hospital for colonoscopy. We allocated 249 patients to PEG 4 L group and 277 patients to PEG 2 L with NaP 90 mL group. Detailed questionnaires were performed to investigate compliance, satisfaction and preference of each method. Bowel preparation quality and segmental quality were evaluated. Success was defined as cecal intubation time less than 20 minutes without any help of supervisors.
  
  
  RESULTS
  Both groups revealed almost the same baseline characteristics except the experience of operation. PEG 4 L group's compliance was lower than PEG 2 L with NaP 90 mL group. Success rate and cecal intubation time was not different between two groups. Overall bowel preparation quality of PEG 2 L with NaP 90 mL group was better than PEG 4 L group. Segmental bowel preparation quality of PEG 2 L with NaP 90 mL group was also better than PEG 4 L group in all segments, especially right side colon. Occurrence of hyperphosphatemia was higher in PEG 2 L with NaP 90 mL group than PEG 4 L group. However, significant adverse event was not reported.
  
  
  CONCLUSIONS
  PEG 2 L with NaP 90 mL method seems to be more effective bowel preparation than PEG 4 L method.
authors.affiliation: Department of Internal Medicine and, Seoul National University Bundang Hospital, Seoungnam, Korea.
authors.forename: Jung Won
authors.initials: JW
authors.lastname: Lee
authors.forename: Na Young
authors.initials: NY
authors.lastname: Kim
authors.forename: Byung Hyo
authors.initials: BH
authors.lastname: Cha
authors.forename: Byoung Hwan
authors.initials: BH
authors.lastname: Lee
authors.forename: Tae Jun
authors.initials: TJ
authors.lastname: Hwang
authors.forename: Yu Jeong
authors.initials: YJ
authors.lastname: Jeong
authors.forename: Tae Hyuck
authors.initials: TH
authors.lastname: Choi
authors.forename: Hee Sup
authors.initials: HS
authors.lastname: Kim
authors.forename: Hyung Joon
authors.initials: HJ
authors.lastname: Myung
authors.forename: Jang Eon
authors.initials: JE
authors.lastname: Kim
authors.forename: Je Hyuck
authors.initials: JH
authors.lastname: Jang
authors.forename: Yeo Myeong
authors.initials: YM
authors.lastname: Kim
authors.forename: Jong Yeop
authors.initials: JY
authors.lastname: Kim
authors.forename: Sang Wook
authors.initials: SW
authors.lastname: Park
authors.forename: Hyun Kyung
authors.initials: HK
authors.lastname: Park
authors.forename: Seung Chul
authors.initials: SC
authors.lastname: Suh
authors.forename: Pyoung Ju
authors.initials: PJ
authors.lastname: Seo
authors.forename: Joon Chang
authors.initials: JC
authors.lastname: Song
authors.forename: Cheol Min
authors.initials: CM
authors.lastname: Shin
authors.forename: Young Ook
authors.initials: YO
authors.lastname: Eum
authors.forename: Jung Hee
authors.initials: JH
authors.lastname: Kwon
authors.forename: Jin Joo
authors.initials: JJ
authors.lastname: Kim
authors.forename: Byeong Jun
authors.initials: BJ
authors.lastname: Song
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Park
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Lee
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003108:Colonic Diseases / Q000175:diagnosis; D003113:Colonoscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010710:Phosphates / Q000008:administration & dosage*; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D012996:Solutions; D011795:Surveys and Questionnaires; D007507:Therapeutic Irrigation
chemical_list: D010710:Phosphates; D012996:Solutions; D011092:Polyethylene Glycols; C018279:sodium phosphate