title: [DNA double strand break and Nijmegen breakage syndrome].
authors.affiliation: jkobayashi@house.rbc.kyoto-u.ac.jp
authors.forename: Junya
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Kenshi
authors.initials: K
authors.lastname: Komatsu
mesh_terms: D017766:Acid Anhydride Hydrolases; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D064007:Ataxia Telangiectasia Mutated Proteins; D002352:Carrier Proteins / Q000502:physiology; D002453:Cell Cycle / Q000235:genetics*; D018797:Cell Cycle Proteins / Q000502:physiology*; D042002:Chromatin Assembly and Disassembly / Q000235:genetics; D053903:DNA Breaks, Double-Stranded; D004260:DNA Repair / Q000235:genetics; D045643:DNA Repair Enzymes / Q000502:physiology; D004261:DNA Replication / Q000235:genetics; D004268:DNA-Binding Proteins / Q000502:physiology; D006801:Humans; D000076228:MRE11 Homologue Protein; D049932:Nijmegen Breakage Syndrome / Q000235:genetics*; D009687:Nuclear Proteins / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000502:physiology; D011995:Recombination, Genetic; D015534:Trans-Activators / Q000502:physiology; D025521:Tumor Suppressor Proteins / Q000502:physiology
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C413163:MDC1 protein, human; C121766:MRE11 protein, human; C112156:NBN protein, human; D009687:Nuclear Proteins; C110513:TOPBP1 protein, human; D015534:Trans-Activators; D025521:Tumor Suppressor Proteins; C576324:ATM protein, human; C576597:ATR protein, human; D064007:Ataxia Telangiectasia Mutated Proteins; D017346:Protein Serine-Threonine Kinases; D000076228:MRE11 Homologue Protein; D017766:Acid Anhydride Hydrolases; C112158:RAD50 protein, human; D045643:DNA Repair Enzymes