title: Indium-catalyzed homo-Nazarov cyclizations of alkenyl cyclopropyl ketones.
abstract: Herein, an efficient Lewis acid catalyzed protocol for the homo-Nazarov cyclizations of alkenyl cyclopropyl ketones is reported. Alkenes bearing β-hydrogens (or silyl groups) provide 1.5:1 mixtures of methylene cyclohexenols and cyclohexenones. When no β-hydrogens (or silyl groups) are present, only cyclohexenones are observed. Products are rapidly formed in good to high yields (up to 93%) under mild conditions and could be readily derivatized.
authors.affiliation: School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30332, USA.
authors.forename: Dadasaheb V
authors.initials: DV
authors.lastname: Patil
authors.forename: Lien H
authors.initials: LH
authors.lastname: Phun
authors.forename: Stefan
authors.initials: S
authors.lastname: France