title: ALSUntangled No. 7: Investigating hyperimmune goat serum (Aimspro) for ALS.
abstract: The mechanism of Aimspro remains unproven; if it is an immunomodulator and/or a modulator of sodium channels, it theoretically could be useful in ALS. A single, detailed but significantly flawed case report documents slowing in decline of certain respiratory functions in a patient claiming to have ALS, who started Aimspro shortly after bipap. Based upon this limited information, ALSUntangled supports further study of Aimspro, either in ALS animal models or in a small phase 2 trial with clear and objective endpoints carried out by skilled trialists familiar with the problems inherent with ALS clinical studies. Until a trial is undertaken, however, we do not support further use of this product by PALS.
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy* / Q000276:immunology; D000818:Animals; D002986:Clinical Trials as Topic; D006041:Goats / Q000097:blood* / Q000276:immunology*; D006801:Humans; D020407:Internet; D044967:Serum / Q000276:immunology*