title: Synthesis and spectroscopy of near infrared fluorescent dyes for investigating dichromic fluorescence.
abstract: We developed a series of near infrared (NIR) cyanine dyes to study dichromic fluorescence phenomenon, which provides new protocols for in vivo optical imaging. Preliminary spectroscopic studies show that dichromic fluorescence correlates with structural symmetry. This feature suggests the potential use of dichromic fluorescent molecules to study biological processes that can alter the structural symmetry of the molecular probes.
authors.affiliation: Department of Radiology, Washington University, 4525 Scott Avenue, St Louis, MO 63110, United States.
authors.forename: Mingfeng
authors.initials: M
authors.lastname: Bai
authors.forename: Samuel
authors.initials: S
authors.lastname: Achilefu
mesh_terms: D002840:Chromates / Q000737:chemistry*; D003287:Contrast Media / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D015335:Molecular Probes / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared
chemical_list: D002840:Chromates; D003287:Contrast Media; D005456:Fluorescent Dyes; D015335:Molecular Probes; C034944:chromic acid