title: Bioconversion of cinnamic acid derivatives by Schizophyllum commune.
abstract: To investigate the production of useful phenols from plant resources, we examined the metabolism of cinnamic acid derivatives by a wood-rotting fungus, Schizophyllum commune. Four cinnamic acid derivatives (cinnamic, p-coumaric, ferulic, and sinapic acids) were tested as substrates. Two main reactions, reduction and cleavage of the side chain, were observed. Reduction of the side chain was confirmed in cinnamic acid and p-coumaric acid metabolism. The side chain cleavage occurred in p-coumaric acid and ferulic acid metabolism but the initial reactions of these acids differed. Sinapic acid was not metabolized by S. commune. p-Hydroxybenzaldehyde accumulation was observed in the culture to which p-coumaric acid was added. This suggests that S. commune is a useful agent for transforming p-coumaric acid into p-hydroxybenzaldehyde.
authors.affiliation: Department of Biological Functional Science, Kyoto Prefectural University, Kyoto, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Nimura
authors.forename: Sho-ichi
authors.initials: S
authors.lastname: Tsujiyama
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Ueno
mesh_terms: D001547:Benzaldehydes / Q000378:metabolism; D002934:Cinnamates / Q000378:metabolism*; D003373:Coumaric Acids / Q000378:metabolism*; D011422:Propionates; D012567:Schizophyllum / Q000378:metabolism*
chemical_list: D001547:Benzaldehydes; D002934:Cinnamates; D003373:Coumaric Acids; D011422:Propionates; C029010:cinnamic acid; C073734:sinapinic acid; C004999:ferulic acid; C495469:p-coumaric acid; C011483:4-hydroxybenzaldehyde