title: Unusual presentation of brain aspergillosis in chronic granulomatous disease.
abstract: Aspergillus is a frequently observed pathogen in patients with chronic granulomatous disease. We report on a patient with chronic granulomatous disease and severe brain aspergillosis with an unusual presentation and favorable course. We discuss the impact of this infection on morbidity and mortality, adequate therapeutic management, and the need to investigate a possible fungal infection, despite nonspecific signs.
authors.affiliation: Division of Pediatric Immunology, Allergy, and Rheumatology, Department of Pediatrics, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. persiorj@fmrp.usp.br
authors.forename: Pérsio
authors.initials: P
authors.lastname: Roxo
authors.forename: Ullissis Pádua
authors.initials: UP
authors.lastname: de Menezes
authors.forename: Antônio
authors.initials: A
authors.lastname: Condino-Neto
authors.forename: Virgínia Paes Leme
authors.initials: VP
authors.lastname: Ferriani
authors.forename: Osvaldo M
authors.initials: OM
authors.lastname: Takayanagui
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D020953:Neuroaspergillosis / Q000150:complications* / Q000175:diagnosis