title: Esophageal preservation in the setting of high-grade dysplasia and superficial cancer.
abstract: The principle treatment for high-grade dysplasia and superficial esophageal cancer is considered esophagectomy. However, novel technologies and innovations in technique have enabled esophageal preservation by endoscopic management in select patients. The concepts and evidence pertaining to esophageal preservation in early stage malignancy are reviewed in detail. A treatment algorithm based upon the current evidence surrounding esophageal preservation is presented.
authors.affiliation: Department of Cardiothoracic Surgery, Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennyslvania 15232, USA.
authors.forename: Shamus R
authors.initials: SR
authors.lastname: Carr
authors.forename: Blair A
authors.initials: BA
authors.lastname: Jobe
mesh_terms: D000465:Algorithms; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology / Q000601:surgery*; D019317:Evidence-Based Medicine; D006801:Humans; D008207:Lymphatic Metastasis; D009092:Mucous Membrane / Q000473:pathology / Q000601:surgery; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D018579:Patient Selection; D018570:Risk Assessment; D016896:Treatment Outcome