title: Advantages of using a lower vs higher dosage of gonadotropins for follicular maturation including cycles of in vitro fertilization-embryo transfer.
abstract: OBJECTIVE
  To demonstrate the benefits of using lower dosage FSH stimulation for follicular maturation in in vitro fertilization (IVF) cycles and in non-IVF cycles.
  
  
  METHODS
  Several studies are evaluated in which either high or lower dosage gonadotropins were used in IVF and non-IVF cycles. The patient population were women either with diminished or normal ovarian egg reserve.
  
  
  RESULTS
  Very poor pregnancy rates were found with high dosage gonadotropins when there was diminished egg reserve. In contrast pregnancy results per transfer were comparable to women with normal egg reserve when low dose gonadotropin regimens were used.
  
  
  CONCLUSIONS
  Low dose gonadotropin regimens have the benefit of reducing costs and risks of ovarian hyperstimulation without reducing efficacy and in some cases actually increasing pregnancy rates.
authors.affiliation: laurie@ccivf.com
authors.forename: J H
authors.initials: JH
authors.lastname: Check
mesh_terms: D000367:Age Factors; D005260:Female; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage*; D006801:Humans; D011247:Pregnancy; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted
chemical_list: D005640:Follicle Stimulating Hormone