title: [Lymph node tuberculosis treatment: from recommendations to practice].
abstract: OBJECTIVE
  Lymph node infection is the most frequent localization of extrapulmonary tuberculosis. However, there is still no consensus on the length of antimicrobial treatment.
  
  
  METHODS
  We conducted a retrospective study in the Department of infectious diseases and internal medicine in the Amiens Teaching Hospital, France. All patients diagnosed with lymph node tuberculosis between 1998 and 2007 were included; some patients presented with bi- or multifocal tuberculosis. The aim of the study was a practice analysis.
  
  
  RESULTS
  We studied 48 medical records, 16 were excluded for lack of more than 40% of data or because lymph node tuberculosis was non-active. The mean age of the 32 patients included was 49 years. The mean duration of treatment was 10.9 months (standard deviation 2.6, median 11, range 6-18). There was no statistical age difference between subgroups (lymph node tuberculosis versus multifocal tuberculosis). There was no significant difference between the 6-month treatment group and the 9-month treatment group in term of clinical response. One relapse was diagnosed, eight patients (25%) were lost to follow-up at 1 year after treatment. DISCUSSION AND REVIEW: No reliable published data was found as to the optimal duration of treatment. A high quality clinical trial should be carried out to suggest a consensus.
authors.affiliation: Service de Pathologie Infectieuse et Tropicale, CHU d'Amiens, place Victor-Pauchet, 80000 Amiens, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Lanoix
authors.forename: Y
authors.initials: Y
authors.lastname: Douadi
authors.forename: A
authors.initials: A
authors.lastname: Borel
authors.forename: C
authors.initials: C
authors.lastname: Andrejak
authors.forename: Y
authors.initials: Y
authors.lastname: El Samad
authors.forename: J-P
authors.initials: JP
authors.lastname: Ducroix
authors.forename: J-L
authors.initials: JL
authors.lastname: Schmit
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019468:Disease Management; D004359:Drug Therapy, Combination; D005260:Female; D005602:France / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D012008:Recurrence; D012189:Retrospective Studies; D013997:Time Factors; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents