title: A case of primary aldosteronism revealed after renal transplantation.
abstract: BACKGROUND
  A 57-year-old woman was referred to a nephrology clinic because of chronic hypokalemia. She had a history of polycystic kidney disease, resistant hypertension, atrial fibrillation, type 2 diabetes, stroke, and end-stage renal disease, and had received a kidney transplant from a deceased donor at the age of 48 years. At presentation, the patient described symptoms of chronic fatigue and muscle aches, but she did not report pareses. Her medications included four antihypertensive agents, glucose-lowering drugs, immunosuppressants, digoxin, a coumarin derivative, and potassium chloride.
  
  
  METHODS
  Full history, physical examination, laboratory testing of blood and urine, including aldosterone-torenin ratio, and a saline infusion test.
  
  
  METHODS
  Primary aldosteronism.
  
  
  RESULTS
  Treatment with spironolactone resulted in prompt control of hypertension and hypokalemia, allowing discontinuation of potassium chloride and reduction in antihypertensive medication.
authors.affiliation: Department of Internal Medicine, Erasmus Medical Center, Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.
authors.forename: Ewout J
authors.initials: EJ
authors.lastname: Hoorn
authors.forename: Dennis A
authors.initials: DA
authors.lastname: Hesselink
authors.forename: Marcia M
authors.initials: MM
authors.lastname: Kho
authors.forename: Joke I
authors.initials: JI
authors.lastname: Roodnat
authors.forename: Willem
authors.initials: W
authors.lastname: Weimar
authors.forename: Jan L
authors.initials: JL
authors.lastname: van Saase
authors.forename: Anton H
authors.initials: AH
authors.lastname: van den Meiracker
authors.forename: Robert
authors.initials: R
authors.lastname: Zietse
mesh_terms: D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000601:surgery*; D016030:Kidney Transplantation; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000628:therapy