title: [Evaluation of cardiovascular risk by the LAP index in non-obese patients with polycystic ovary syndrome].
abstract: OBJECTIVE
  To analyze the cardiovascular risk of non-obese women with polycystic ovary syndrome (PCOS) by the LAP index (lipid accumulation product).
  
  
  METHODS
  283 patients (18-34 years) assigned at the University Hospital of the Federal University of Rio Grande do Norte, Natal-RN, were divided into four groups: 1) lean PCOS (n = 35); 2) healthy lean (n = 162); 3) overweight PCOS (n = 28); 4) healthy overweight (n = 58).
  
  
  RESULTS
  Patients with PCOS showed higher values of the LAP index than healthy controls: lean (22.26 vs. 15.87 cm.mmol/L; p = 0.007); overweight (40.83 vs. 26.32 cm.mmol/L; p = 0.001). The percentage of women above the 75th percentile of the LAP index was also higher in the subgroups with PCOS: lean (17.1 vs. 6.8%; p = 0.04); overweight (37.5 vs. 13.8%; p = 0.01).
  
  
  CONCLUSIONS
  In our sample, patients with PCOS showed higher cardiovascular risk assessed by the LAP index in relation to healthy women, even in the absence of obesity.
authors.affiliation: Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.
authors.forename: Eduardo Caldas
authors.initials: EC
authors.lastname: Costa
authors.forename: Joceline Cássia Ferezini de
authors.initials: JC
authors.lastname: Sá
authors.forename: Elvira Maria Mafaldo
authors.initials: EM
authors.lastname: Soares
authors.forename: Telma Maria Araújo Moura
authors.initials: TM
authors.lastname: Lemos
authors.forename: Técia Maria de Oliveira
authors.initials: TM
authors.lastname: Maranhão
authors.forename: George Dantas
authors.initials: GD
authors.lastname: Azevedo
mesh_terms: D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000209:etiology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D009765:Obesity / Q000175:diagnosis* / Q000453:epidemiology; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D018709:Statistics, Nonparametric; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference / Q000502:physiology*; D055815:Young Adult
chemical_list: D014280:Triglycerides