title: Curcuma as a parasiticidal agent: a review.
abstract: Members of the Curcuma plant species (Zingiberaceae) have been used for centuries in cooking, cosmetics, staining and in traditional medicine as "omnipotent" remedies. Herbal preparations made with, and molecules extracted from, Curcuma have been shown to possess a wide variety of pharmacological properties against malignant proliferation, hormonal disorders, inflammation, and parasitosis among other conditions. This review evaluates Curcuma and its associated bioactive compounds, particularly focusing on studies examining the parasiticidal activity of these components against the tropical parasites Plasmodium, leishmania, Trypanosoma, Schistosoma and more generally against other cosmopolitan parasites (nematodes, Babesia, Candida, Giardia, Coccidia and Sarcoptes).
authors.affiliation: Laboratoire de pharmacochimie des substances naturelles et pharmacophores redox, UMR 152, UPS, Université de Toulouse, Toulouse, France. mohamed.haddad@ird.fr
authors.forename: Mohamed
authors.initials: M
authors.lastname: Haddad
authors.forename: Michel
authors.initials: M
authors.lastname: Sauvain
authors.forename: Eric
authors.initials: E
authors.lastname: Deharo
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001404:Babesiosis / Q000188:drug therapy / Q000469:parasitology; D003048:Coccidiosis / Q000188:drug therapy / Q000469:parasitology; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D005873:Giardiasis / Q000188:drug therapy / Q000469:parasitology; D006373:Helminthiasis / Q000188:drug therapy / Q000469:parasitology; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy / Q000469:parasitology; D008288:Malaria / Q000188:drug therapy / Q000469:parasitology; D010271:Parasites / Q000187:drug effects* / Q000472:pathogenicity; D010272:Parasitic Diseases / Q000188:drug therapy* / Q000469:parasitology; D028321:Plant Preparations / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D012532:Scabies / Q000188:drug therapy / Q000469:parasitology; D012552:Schistosomiasis / Q000188:drug therapy / Q000469:parasitology; D014352:Trypanosomiasis / Q000188:drug therapy / Q000469:parasitology
chemical_list: D000977:Antiparasitic Agents; D028321:Plant Preparations; D003474:Curcumin