title: Annexins.
abstract: Annexins are multifunctional lipid-binding proteins. Plant annexins are expressed throughout the life cycle and are under environmental control. Their association or insertion into membranes may be governed by a range of local conditions (Ca(2+), pH, voltage or lipid identity) and nonclassical sorting motifs. Protein functions include exocytosis, actin binding, peroxidase activity, callose synthase regulation and ion transport. As such, annexins appear capable of linking Ca(2+), redox and lipid signalling to coordinate development with responses to the biotic and abiotic environment. Significant advances in plant annexin research have been made in the past 2 yr. Here, we review the basis of annexin multifunctionality and suggest how these proteins may operate in the life and death of a plant cell.
authors.affiliation: Department of Plant Sciences, University of Cambridge, Cambridge, UK.
authors.forename: Anuphon
authors.initials: A
authors.lastname: Laohavisit
authors.forename: Julia M
authors.initials: JM
authors.lastname: Davies
mesh_terms: D000595:Amino Acid Sequence; D017302:Annexins / Q000032:analysis / Q000737:chemistry / Q000502:physiology*; D003600:Cytosol / Q000378:metabolism; D004777:Environment; D017136:Ion Transport; D050356:Lipid Metabolism; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000032:analysis / Q000737:chemistry / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D017434:Protein Structure, Tertiary; D021381:Protein Transport; D016415:Sequence Alignment
chemical_list: D017302:Annexins; D010940:Plant Proteins