title: In situ complex adenocarcinoma on the femoral part of the hindlimb in an Asian Leaf Turtle (Cyclemys dentata).
abstract: A heterotopic in situ complex adenocarcinoma developing on the hindlimb is reported for the first time from an Asian Leaf Turtle (Cyclemys dentata). The tumour mechanically hampered the movement of the animal. The turtle refused to eat and consequently developed a poor condition. Histopathology of the tumour revealed all characteristics of a well-differentiated adenocarcinoma originating from apocrine gland-like tissue: the irregular, tubular structures varying in size were generally lined by two to four layers of cuboidal to columnar neoplastic epithelial cells. Claudin-5, pancytokeratin, cytokeratin, vimentin, α-SMA and Ki-67 immunohistochemical antibodies were employed for characterising the tumour. The diagnosis was a complex adenocarcinoma originating from apocrine gland-like tissue in a turtle.
authors.affiliation: Department of Pathology and Forensic Veterinary Medicine, Szent István University, István u. 2 H-1078 Budapest, Hungary. Gal.Janos@aotk.szie.hu
authors.forename: János
authors.initials: J
authors.lastname: Gál
authors.forename: Míra
authors.initials: M
authors.lastname: Mándoki
authors.forename: Tamás
authors.initials: T
authors.lastname: Sátorhelyi
authors.forename: Csaba
authors.initials: C
authors.lastname: Jakab
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D005260:Female; D006614:Hindlimb / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000662:veterinary*; D014426:Turtles