title: Acquired myelinated nerve fibers in association with optic disk drusen.
abstract: Myelinated retinal nerve fibers are a well-recognized anomaly of the ocular fundus associated with many ocular and systemic conditions. Myelination is almost always congenital and stable, but progression has been documented in rare cases. Optic disk drusen are the result of a degenerative process at the optic nerve head and are often found incidentally on ophthalmologic examination. To our knowledge, optic disk drusen have only been reported once in association with acquired and progressive myelinated retinal nerve fibers. We present 2 such cases and consider the implications for the pathogenesis of myelinated nerve fibers.
authors.affiliation: Department of Pediatric Ophthalmology, Le Centre Hospitalier Universitaire Mère-Enfant Sainte-Justine, University of Montreal, Montreal, Canada.
authors.forename: Renaud
authors.initials: R
authors.lastname: Duval
authors.forename: Karim
authors.initials: K
authors.lastname: Hammamji
authors.forename: Maryam
authors.initials: M
authors.lastname: Aroichane
authors.forename: Jacques L
authors.initials: JL
authors.lastname: Michaud
authors.forename: Luis H
authors.initials: LH
authors.lastname: Ospina
mesh_terms: D000015:Abnormalities, Multiple; D016080:Arachnoid Cysts / Q000150:complications; D002648:Child; D005145:Face / Q000002:abnormalities; D005260:Female; D006402:Hematologic Diseases / Q000150:complications; D006801:Humans; D007223:Infant; D019586:Intracranial Hypertension / Q000150:complications*; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology; D015594:Optic Disk Drusen / Q000209:etiology* / Q000473:pathology*; D015837:Vestibular Diseases / Q000150:complications