title: Diverse role of microbially bioconverted product of cabbage (Brassica oleracea) by Pseudomonas syringe pv. T1 on inhibiting Candida species.
abstract: This study was carried out to evaluate the anticandidal effects of bioconverted product, obtained from the microbial conversion of cabbage (Brassica oleracea) by a bacterial strain Pseudomonas syringe pv. T1 (Ps-T1) against various isolates of Candida species. The diameters of zones of inhibition of bioconverted product of cabbage (10 μl, corresponding to 500 μg/disc) against Candida albicans KACC 30003 and 30062, Candida geochares KACC 30061, Candida saitoana KACC 41238 and Candida glabrata P00368 were found between 10±1 and 16±0.8 mm. The bioconverted product was tested for the minimum inhibitory and minimum fungicidal concentration values against the tested pathogens which were found in the range of 125-500 and 125-500 μg/ml, respectively. On the viable counts of the tested fungal pathogens, the bioconverted product showed a remarkable anticandidal effect. Also the study of using scanning electron microscopy on the morphology of C.albicans KACC 30062 revealed potential detrimental effect of bioconverted product at MIC concentration. The results of this study suggest that bioconverted product of cabbage by Ps-T1 holds potential therapeutic value and medicinal significance to control Candida species.
authors.affiliation: School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea.
authors.forename: Vivek K
authors.initials: VK
authors.lastname: Bajpai
authors.forename: Sun Chul
authors.initials: SC
authors.lastname: Kang
authors.forename: Euiho
authors.initials: E
authors.lastname: Park
authors.forename: Weon-Tai
authors.initials: WT
authors.lastname: Jeon
authors.forename: Kwang-Hyun
authors.initials: KH
authors.lastname: Baek
mesh_terms: D000935:Antifungal Agents; D001937:Brassica / Q000382:microbiology*; D002175:Candida / Q000187:drug effects*; D028321:Plant Preparations / Q000494:pharmacology*; D044224:Pseudomonas syringae / Q000378:metabolism*
chemical_list: D000935:Antifungal Agents; D028321:Plant Preparations