title: [Finnish disease heritage].
abstract: The Finnish disease heritage refers to rare hereditary diseases that occur in the Finnish population in a relatively larger proportion than in other populations. The genes underlying all of the 36 diseases of the disease heritage have been identified. Together with her group and collaborators, Leena Palotie identified 15 of these, and this review includes the description of some of these achievements. As a result of the so-called founder effect, one predominant mutation underlying these diseases occurs in our population, facilitating the diagnostics of these diseases in our country.
authors.forename: Marjo
authors.initials: M
authors.lastname: Kestilä
authors.forename: Elina
authors.initials: E
authors.lastname: Ikonen
authors.forename: Anna-Elina
authors.initials: AE
authors.lastname: Lehesjoki
mesh_terms: D005387:Finland / Q000453:epidemiology; D018703:Founder Effect; D030342:Genetic Diseases, Inborn / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D009154:Mutation / Q000235:genetics*