title: [Correction of antioxidant system disorders in children with acute intestinal infection].
abstract: Administration of reamberin leads to rapid reduction of the intoxication symptoms, improves general condition, and reduces fever stage duration. The dynamics of inflammatory symptoms is characterized by decreasing duration of hemocolitis in comparison that in patients receiving glucose-salt solutions. Reamberin accelerates normalization of the chemiluminescence indices, reduces the intensity of oxidative processes (to within 3-5 days) in patients with high level of free-radical oxidation, and leads to decreasing endogenous intoxication on early terms of the disease. Removal of the dysbalance between oxidation and antioxidant systems, especially in cases of serious shigellosis and in patients with high level of lipid peroxidation, favors a decrease in the damaging action of free radicals and eliminates metabolic disturbances in children within early reconvalesce period.
authors.forename: O V
authors.initials: OV
authors.lastname: Tikhomirova
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
authors.forename: E V
authors.initials: EV
authors.lastname: Mikhaĭlova
authors.forename: L V
authors.initials: LV
authors.lastname: Govorova
mesh_terms: D000293:Adolescent; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004403:Dysentery / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D005609:Free Radicals / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007223:Infant; D008536:Meglumine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D018384:Oxidative Stress / Q000187:drug effects*; D012720:Severity of Illness Index; D013386:Succinates / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D005609:Free Radicals; C549374:Reamberin; D013386:Succinates; D008536:Meglumine