title: "One-pot" tandem C-H borylation/1,4-conjugate addition/reduction sequence.
abstract: A microwave-assisted, one-pot, iridium-catalyzed aromatic C-H borylation/rhodium-catalyzed 1,4-conjugate addition sequence provides a highly robust protocol suitable for high-throughput array synthesis. Selective formation of either β-aryl-substituted ketones or the corresponding alcohols can be achieved in good overall yields by simple variation of the reaction conditions.
authors.affiliation: Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
authors.forename: Hazmi
authors.initials: H
authors.lastname: Tajuddin
authors.forename: Lena
authors.initials: L
authors.lastname: Shukla
authors.forename: Aoife C
authors.initials: AC
authors.lastname: Maxwell
authors.forename: Todd B
authors.initials: TB
authors.lastname: Marder
authors.forename: Patrick G
authors.initials: PG
authors.lastname: Steel
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry; D008872:Microwaves; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D001896:Boron Compounds; D007495:Iridium; D002244:Carbon; D006859:Hydrogen