title: Myocardial infarction in prediabetic patients: role of blood pressure dyshomeostasis.
abstract: Male gender and fasting sugar level at pre diabetic range are two of the recognized risk factors associated with coronary artery disease. Recently it was found that although males are at increased incidence of myocardial infarction (MI), the severity of disease is same for both genders among pre-diabetic myocardial infarction cases. In this study, we have retrospectively analyzed various biochemical and physiological parameters and cardiac markers of patients admitted for the first instance of myocardial infarction. We found an evidence of impairment in blood pressure homeostasis in female patients which could be one of the factors responsible for the equal degree of severity in myocardial infarction among females compared to males, despite lower incidence of MI in them.
authors.affiliation: Department of Biochemistry, Pondicherry Institute of Medical Sciences, Pondicherry.
authors.forename: Nivedita
authors.initials: N
authors.lastname: Nanda
authors.forename: Sanat Kumar
authors.initials: SK
authors.lastname: Sen
authors.forename: Mark C
authors.initials: MC
authors.lastname: Arokiaraj
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006706:Homeostasis; D006801:Humans; D007194:India; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D011236:Prediabetic State / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012737:Sex Factors; D019210:Troponin I / Q000097:blood
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008055:Lipids; D019210:Troponin I; D003402:Creatine Kinase