title: A capacity for mixing in capillary wells for microplates.
abstract: Sample/reagent mixing is important in microplate instrumentation and the approach of mixing prior to dispensation into the wells can be problematic when assays involve a mixture of different proportions of reagents. We demonstrate here with capillaries, a simple and highly effective method that uses air actuation and liquid surface tension to create pendant drops in which the inherent inner circulatory flow within accomplishes mixing. The approach portends the capability to be incorporated into microplates in order to provide a useful feature for assay investigations.
authors.affiliation: Laboratory for Optics, Acoustics, and Mechanics, Department of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria 3800, Australia.
authors.forename: Jonathan Kok Keung
authors.initials: JK
authors.lastname: Lye
authors.forename: Tuck Wah
authors.initials: TW
authors.lastname: Ng
authors.forename: Adrian
authors.initials: A
authors.lastname: Neild
authors.forename: Oi Wah
authors.initials: OW
authors.lastname: Liew
mesh_terms: D000388:Air; D055616:Microtechnology / Q000379:methods*; D009038:Motion; D011312:Pressure; D013499:Surface Properties