title: Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia.
abstract: Four phenolics, salviaplebeiaside (1), γ-tocopherol (2), chrysosplenol-D (4), and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments. The structures of compounds 1-5 were established by spectroscopic means. The antibacterial activities of the compounds were assessed against Escherichia coli, Bacillus subtilis, Micrococcus tetragenus and Pseudomonas fluorescens. Chrysosplenol-D (4) exhibited activities against all the four spoilage microorganisms.
authors.affiliation: Key Laboratory of Tea Biochemistry and Biotechnology of Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, 130 West Changjiang Road, Hefei 230036, China.
authors.forename: Tie-Jun
authors.initials: TJ
authors.lastname: Ling
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Ling
authors.forename: Yuan-Jun
authors.initials: YJ
authors.lastname: Chen
authors.forename: Xiao-Chun
authors.initials: XC
authors.lastname: Wan
authors.forename: Tao
authors.initials: T
authors.lastname: Xia
authors.forename: Xian-Feng
authors.initials: XF
authors.lastname: Du
authors.forename: Zheng-Zhu
authors.initials: ZZ
authors.lastname: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D047310:Apigenin / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology; D008837:Micrococcus / Q000187:drug effects; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D011551:Pseudomonas fluorescens / Q000187:drug effects; D012855:Sitosterols / Q000737:chemistry / Q000494:pharmacology; D014810:Vitamin E / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D020950:Vitex / Q000737:chemistry*; D024504:gamma-Tocopherol / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D012855:Sitosterols; D014810:Vitamin E; C025473:gamma-sitosterol; C002421:tocopherylquinone; D047310:Apigenin; D024504:gamma-Tocopherol; C049772:isovitexin