title: Time-resolved diffuse optical spectroscopy: a differential absorption approach.
abstract: A method is presented for the estimate of spectral changes in the absorption properties of turbid media from time-resolved diffuse optical spectroscopy. The method relies on the hypothesis of constant scattering over the wavelength range of interest, but no limitations come from the sample size and shape as the method is derived directly from the Beer-Lambert law. The effects of a moderate spectral dependence of the scattering properties and of the non-ideal instrument response function were investigated theoretically, and the results were confirmed experimentally, showing that the method can be profitably applied in cases of practical interest.
authors.affiliation: Dipartimento di Fisica, Politecnico di Milano, piazza Leonardo da Vinci 32, 20133 Milan, Italy. paola.taroni@fisi.polimi.it
authors.forename: Paola
authors.initials: P
authors.lastname: Taroni
authors.forename: Andrea
authors.initials: A
authors.lastname: Bassi
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Spinelli
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Cubeddu
authors.forename: Antonio
authors.initials: A
authors.lastname: Pifferi