title: [Assessment of risk of cardiovascular diseases in persons of young age].
abstract: Cardiovascular pathology appears to be big socially meaningful problem as it occupies leading place in structure of mortality and loss of working capacity in economically developed countries. Social value of the problem is enforced by observed in recent years tendency to increase of mortality of cardiovascular diseases (CVD) in young age persons. It has been shown in large prospective studies that traditional CVD risk factors such as sex, lipid spectrum of blood, smoking, arterial hypertension, obesity, and hyperglycemia correlate with pathologoanatomical findings of atherosclerotic plaques in coronary arteries and abdominal aorta of young people aged 15-34 years. Proper and well-defined stratification of risk in young people will allow to approach solution of the problem of morbidity and mortality in older age. This work contains data on results of prospective multicenter epidemiological and clinical studies devoted to investigation of established and novel risk factors in the young, their contribution to development of atherosclerotic process, morbidity and mortality caused by CVD in later age. We also analyze prognostic potential of existing at this moment in the world scales for assessment of cardiovascular risk specifically in this group of population, and present data on prognostic models created specially for assessment of CVD risk in persons of young age.
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Zvolinskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Aleksandrov
mesh_terms: D017668:Age of Onset; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control; D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000453:epidemiology; D004185:Disability Evaluation; D018450:Disease Progression; D016021:Epidemiologic Studies; D014943:Global Health; D006293:Health Promotion; D006801:Humans; D009026:Mortality; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods* / Q000639:trends; D018571:Sentinel Surveillance