title: Correction of field inhomogeneity effects on limited k-space MRSI data using anatomical constraints.
abstract: Magnetic field inhomogeneity is a long-standing problem in magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI). Specifically, in MRSI, field inhomogeneity, if not corrected, can cause frequency shifts, line broadening, and lineshape distortions in the spectral peaks. This paper addresses the problem of correcting the field inhomogeneity effects on limited k-space MRSI data. A penalized maximum-likelihood method is proposed, which enables the use of anatomical constraints for improving the correction performance with only limited k-space data. Simulation results are shown to demonstrate the effectiveness of the proposed method.
authors.affiliation: School of Electronic Information, Wuhan University, 430079, China. pengxi840120@hotmail.com
authors.forename: Xi
authors.initials: X
authors.lastname: Peng
authors.forename: Hien
authors.initials: H
authors.lastname: Nguyen
authors.forename: Justin
authors.initials: J
authors.lastname: Haldar
authors.forename: Diego
authors.initials: D
authors.lastname: Hernando
authors.forename: Xian-Pei
authors.initials: XP
authors.lastname: Wang
authors.forename: Zhi-Pei
authors.initials: ZP
authors.lastname: Liang
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology* / Q000378:metabolism*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014018:Tissue Distribution