title: [Novel conservative domain of SAYP coactivator mediates TFIID and Brahma transcriptional complexes interaction].
abstract: In the S2 cell system of Drosophila melanogaster a key protein domain mediating the interaction of TFIID and Brahma transcriptional complexes into the BTFly supercomplex has been shown to be an evolutionary conserved SAY domain of the SAYP. TFIID and Brahma coactivators participated in the reporter gene activation induced by the SAY domain in cellular nuclei. The TFIID and Brahma components directly interacting with the SAY domain were identified.
authors.forename: N E
authors.initials: NE
authors.lastname: Vorob'eva
authors.forename: N V
authors.initials: NV
authors.lastname: Soshnikova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Nikolenko
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Kuz'mina
authors.forename: E N
authors.initials: EN
authors.lastname: Nabirochkina
authors.forename: S G
authors.initials: SG
authors.lastname: Georgieva
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Shidlovskiĭ
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster; D046912:Multiprotein Complexes / Q000235:genetics / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism*; D035362:Transcription Factor TFIID / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000502:physiology*
chemical_list: D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; D046912:Multiprotein Complexes; D015534:Trans-Activators; D035362:Transcription Factor TFIID; D014157:Transcription Factors; C086469:brm protein, Drosophila; C499490:e(y)3 protein, Drosophila