title: Multiple basal cell carcinomas after long-term exposure to hydrazine: case report and review of the literature.
abstract: Hydrazine (N(2)H(4)) is a clear, inorganic colourless liquid. It is known to be a skin sensitizer, a corrosive agent and it causes dermatitis on contact. Hydrazine is employed in chemical plants, used as a corrosion inhibitor for feed waters and may be added to rocket fuels. The authors report the case of a 68-year-old man with multiple basal cell carcinomas (BCCs) covering his arms and face. The patient worked in a steam power plant with extensive exposure to hydrazine for a period of over 10 years. The present case report strongly suggests that there may be a correlation between the long-term exposure to hydrazine and an increased risk for multiple BCCs.
authors.affiliation: Department of Dermatology and Allergy am Biederstein, Technical University Munich, Munich, Germany.
authors.forename: B A
authors.initials: BA
authors.lastname: Aigner
authors.forename: U
authors.initials: U
authors.lastname: Darsow
authors.forename: M
authors.initials: M
authors.lastname: Grosber
authors.forename: J
authors.initials: J
authors.lastname: Ring
authors.forename: S G
authors.initials: SG
authors.lastname: Plötz
mesh_terms: D000368:Aged; D001132:Arm; D002280:Basal Cell Carcinoma / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery; D005145:Face; D006223:Hamartoma Syndrome, Multiple; D006801:Humans; D006834:Hydrazines / Q000633:toxicity*; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D016273:Occupational Exposure; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery
chemical_list: D006834:Hydrazines; C029424:hydrazine