title: Use of Shannon information in treatment of high resolution diffusion MRI.
abstract: Diffusion MRI allows the obtaining of an approximation of the water displacement's probability density function (PDF) and orientation distribution function (ODF). Examples of techniques used in obtaining these distributions being q-space imaging (QSI), and q-ball imaging (QBI), respectively. Shannon information quantifies the discriminative power of a symbol based on its probability. We quantified the information amount of a white matter fiber bundle being used to discriminate those fibers using specific diffusion MRI data treatment techniques. The equations developed are new and it is also described how they will help in future experimental calculations. An example of experimental ODF surfaces and ODF based white matter fiber tracking in living humans is also shown to highlight possible future advantages of Shannon information usage in describing crossing white matter fiber bundles.
authors.affiliation: IBILI, Faculty of Medicine, University of Coimbra, 3000-548, Portugal. nflori@fmed.uc.pt
authors.forename: Nicolas F
authors.initials: NF
authors.lastname: Lori
authors.forename: Carlos
authors.initials: C
authors.lastname: Santos
mesh_terms: D000465:Algorithms; D001921:Brain / Q000473:pathology*; D001931:Brain Mapping / Q000379:methods; D003627:Data Interpretation, Statistical; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional; D015233:Models, Statistical; D008962:Models, Theoretical; D009413:Nerve Fibers, Myelinated; D011336:Probability; D012815:Signal Processing, Computer-Assisted; D012984:Software