title: Capillary separations in metabolomics.
abstract: Capillary-based separations offer increased resolution, low mass LOD and, in the case of MS, higher sensitivity. The chemical diversity and wide dynamic range of the metabolome requires systems that offer breadth and depth of analysis. In this review, we will highlight novel chemical innovations, technological advancements and various applications of capillary separations in the field of metabolomics.
authors.affiliation: Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
authors.forename: James L
authors.initials: JL
authors.lastname: Edwards
mesh_terms: D000818:Animals; D005591:Chemical Fractionation / Q000295:instrumentation / Q000379:methods*; D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D019075:Electrophoresis, Capillary; D006801:Humans; D055432:Metabolomics / Q000295:instrumentation / Q000379:methods*