title: Pain in cancer patients: the Greek experience.
abstract: OBJECTIVE
  Pain is not only one of the most undesirable side effects of cancer but also one of its major complications. This study attempted to evaluate and describe the pain characteristics and pain control in patients with advanced cancer and to identify factors related to effective analgesic treatment.
  
  
  METHODS
  A descriptive cross-sectional study involving the eight larger oncology centres in Greece was conducted in 2008. Cancer patients (n = 134) attending the oncology outpatient departments were interviewed using a 35-item questionnaire regarding pain- and treatment-related characteristics.
  
  
  RESULTS
  The great majority of the patients (72%) with advanced malignancy reported high pain intensity and 66.4% experienced the pain as continuous. Although most patients (81%) responded to treatment, more than 30% reported side effects and asked for treatment to change. Better informed patients about the disease showed higher response to pain treatment (OR 3.21; 95%CI 1.28-8.01). Adherence to treatment was related to pain response (OR 3.05; 95%CI 1.06-8.75), whereas negative attitudes and feelings toward treatment were related with reluctance to take analgesic treatment (OR 4.27; 95%CI 1.31-13.89). Patients' request for changing medication was significantly related to the presence of side effects (OR 8.26; 95%CI 2.80-24.42) and pain response to treatment (OR 0.09; 95%CI 0.03-0.31).
  
  
  CONCLUSIONS
  Negative attitudes and feelings toward treatment combined with deficits in patient education/information seem to influence both pain response and therapy compliance suggesting the need for more comprehensive approach to pain management of cancer patients.
authors.affiliation: Department of Public Health, University of Patras, Greece. ecalexop@upatras.gr
authors.forename: Evangelos C
authors.initials: EC
authors.lastname: Alexopoulos
authors.forename: Persefoni
authors.initials: P
authors.lastname: Koutsogiannou
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Moratis
authors.forename: Angeliki
authors.initials: A
authors.lastname: Mestousi
authors.forename: Eleni
authors.initials: E
authors.lastname: Jelastopulu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000700:Analgesics / Q000627:therapeutic use*; D001294:Attitude to Health; D003430:Cross-Sectional Studies; D005260:Female; D006115:Greece; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D059408:Pain Management / Q000379:methods*; D010353:Patient Education as Topic; D036301:Qualitative Research; D016896:Treatment Outcome; D016903:Drug Monitoring
chemical_list: D000700:Analgesics