title: Chemoselective phosphine-catalyzed cascade annulations between two different activated alkenes: highly diastereoselective syntheses of polysubstituted cyclohexanes and cyclopentenes.
abstract: Chemoselective phosphine-catalyzed cascade [2 + 2 + 2] and [2 + 2 + 1] annulations between two molecules of 2-arylmethylidene cyanoacetates or malononitriles and one molecule of α,β-unsaturated ketones have been developed. Under the nucleophilic catalysis of PPh(3) or PBu(3) (10 mol%), a highly diastereoselective synthesis of polysubstituted cyclohexanes or cyclopentenes has been successfully achieved, respectively.
authors.affiliation: The State Key Laboratory of Elemento-Organic Chemistry and Department of Chemistry, Nankai University, 94 Weijin Road, Tianjin 300071, China.
authors.forename: Lingchao
authors.initials: L
authors.lastname: Cai
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Guiping
authors.initials: G
authors.lastname: Wu
authors.forename: Haibin
authors.initials: H
authors.lastname: Song
authors.forename: Zhengjie
authors.initials: Z
authors.lastname: He