title: Fluence-convolution broad-beam (FCBB) dose calculation.
abstract: IMRT optimization requires a fast yet relatively accurate algorithm to calculate the iteration dose with small memory demand. In this paper, we present a dose calculation algorithm that approaches these goals. By decomposing the infinitesimal pencil beam (IPB) kernel into the central axis (CAX) component and lateral spread function (LSF) and taking the beam's eye view (BEV), we established a non-voxel and non-beamlet-based dose calculation formula. Both LSF and CAX are determined by a commissioning procedure using the collapsed-cone convolution/superposition (CCCS) method as the standard dose engine. The proposed dose calculation involves a 2D convolution of a fluence map with LSF followed by ray tracing based on the CAX lookup table with radiological distance and divergence correction, resulting in complexity of O(N(3)) both spatially and temporally. This simple algorithm is orders of magnitude faster than the CCCS method. Without pre-calculation of beamlets, its implementation is also orders of magnitude smaller than the conventional voxel-based beamlet-superposition (VBS) approach. We compared the presented algorithm with the CCCS method using simulated and clinical cases. The agreement was generally within 3% for a homogeneous phantom and 5% for heterogeneous and clinical cases. Combined with the 'adaptive full dose correction', the algorithm is well suitable for calculating the iteration dose during IMRT optimization.
authors.affiliation: TomoTherapy Inc., Madison, WI 53717, USA. wlu@tomotherapy.com
authors.forename: Weiguo
authors.initials: W
authors.lastname: Lu
authors.forename: Mingli
authors.initials: M
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D003201:Computers; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011829:Radiation Dosage; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated