title: [Detection and diagnostic significance of carcinoembryonic antigen messenger ribonucleic acid in lung cancer tissues].
abstract: BACKGROUND
  To evaluate the clinical value of carcinoembryonic antigen messenger ribonucleic acid ( CEA-mRNA) detection in the diagnosis of lung carcinoma.
  
  
  METHODS
  CEA-mRNA expression was detected in 32 patients with lung carcinoma by reverse transcriptase-polymerase chain reaction ( RT-PCR) , and 11 patients with benign pulmonary diseases as control.
  
  
  RESULTS
  The positive rate of CEA-mRNA was 84. 4% ( 27/ 32) in lung cancer group. And there was no positive case of CEA-mRNA in control group. The specificity was 100% and the sensitivity was 84. 4% in the diagnosis of lung carcinoma.
  
  
  CONCLUSIONS
  CEA-mRNA detection by RT-PCR method may be helpful to diagnosis and differential diagnosis of lung cancer and be of clinical value.
authors.affiliation: Central Laboratory , Affiliated Hospital, Chengde Medical College, Chengde, Hebei 067000, P. R. China.
authors.forename: C
authors.initials: C
authors.lastname: Xue
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.forename: L
authors.initials: L
authors.lastname: Song
authors.forename: L
authors.initials: L
authors.lastname: Sun