title: [Effects of finasteride on hematuria associated with benign prostatic hyperplasia: a meta-analysis].
abstract: OBJECTIVE
  To systematically evaluate the effects of finasteride on hematuria associated with benign prostatic hyperplasia (BPH).
  
  
  METHODS
  We electronically searched MEDLINE (December 1966-April 2009), EMBASE (December 1974-April 2009), The Cochrane Library (Issue 1, 2009), CNKI (December 1994-April 2009), VIP (December 1989-April 2009) and CBM (December 1978-April 2009) , and handsearched several relevant journals as well. Randomized controlled trials were assessed with the methods recommended by the Cochrane Collaboration. The data were screened and systematically analyzed by at least two reviewers independently using the RevMan 5.0 software.
  
  
  RESULTS
  Compared with the placebo control group, the finasteride group showed a significantly decreased incidence of hematuria during the 12 months follow-up period (OR 0.11, 95% CI: 0.06-0.21, P < 0.05).
  
  
  CONCLUSIONS
  Finasteride has desirable therapeutic and preventive effects on BPH-associated hematuria. More well-designed multicentered randomized controlled trials of large sample size are invited to provide further evidence for this conclusion.
authors.affiliation: Department of Urology, Central Hospital of Shaoyang, Shaoyang, Hunan 422000, China. jy3485@sina.com
authors.forename: Yi
authors.initials: Y
authors.lastname: Jiang
authors.forename: Yong-Fu
authors.initials: YF
authors.lastname: Long
mesh_terms: D018120:Finasteride / Q000627:therapeutic use*; D006417:Hematuria / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000150:complications / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic
chemical_list: D018120:Finasteride