title: Antilipidemic activity of organic solvent extract from Sorghum bicolor on rats with diet-induced obesity.
abstract: The present study evaluated the antiobesity and lipid-lowering effects from dichloromethane and ethyl acetate extracts of Hwanggeumchal Sorghum varieties on Sorghum bicolor. The Hwanggeumchal Sorghum ethyl acetate extracts significantly reduced the plasma total cholesterol and triglyceride levels significantly when given orally at a dose of 50 and 300 mg/kg/day to the high-fat diet-induced obese rats for 2 weeks. These findings demonstrate the excellent pharmacological potential of Hwanggeumchal Sorghum varieties to prevent obesity.
authors.affiliation: Department of Applied Life Science, Kon Kuk University, Seoul, South Korea.
authors.forename: Ill-Min
authors.initials: IM
authors.lastname: Chung
authors.forename: Min-A
authors.initials: MA
authors.lastname: Yeo
authors.forename: Sun-Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Myong-Jo
authors.initials: MJ
authors.lastname: Kim
authors.forename: Dong-Sik
authors.initials: DS
authors.lastname: Park
authors.forename: Hyung-In
authors.initials: HI
authors.lastname: Moon
mesh_terms: D000085:Acetates / Q000737:chemistry; D000818:Animals; D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D059305:Diet, High-Fat; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008055:Lipids / Q000097:blood; D008297:Male; D008752:Methylene Chloride / Q000737:chemistry; D009765:Obesity / Q000097:blood / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D012997:Solvents / Q000737:chemistry; D045868:Sorghum
chemical_list: D000085:Acetates; D019440:Anti-Obesity Agents; D000960:Hypolipidemic Agents; D008055:Lipids; D010936:Plant Extracts; D012997:Solvents; D008752:Methylene Chloride; C007650:ethyl acetate