title: [Pyoderma gangrenosum: 6 cases].
abstract: Pyoderma gangrenosum (PG) is an uncommon extensive cutaneous ulceration belonging to the neutrophilic disease spectrum. It is associated to a systemic disease in almost 50% of cases. The diagnosis primarily relies on clinico-pathological features and the treatment is empirical. We report a retrospective series of 6 observations of PG (4 women and 2 men, median age = 43 years) enrolled over 15 years. The diagnosis was established based on the presence of 2 major criteria and 2 minor criteria of the disease. In 3 patients, PG was associated to an already known ulcerative colitis. The treatment consisted in general corticotherapy.
authors.affiliation: Service de Dermatologie, Hôpital Charles Nicolle, Tunis, Tunisie. fekih.nadia@planet.tn
authors.forename: N
authors.initials: N
authors.lastname: El Fékih
authors.forename: N
authors.initials: N
authors.lastname: Kerkeni
authors.forename: M
authors.initials: M
authors.lastname: Kharfi
authors.forename: D
authors.initials: D
authors.lastname: Baccouche
authors.forename: F
authors.initials: F
authors.lastname: Zéglaoui
authors.forename: B
authors.initials: B
authors.lastname: Fazaa
authors.forename: R
authors.initials: R
authors.lastname: Kamoun Mohamed
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000188:drug therapy; D012189:Retrospective Studies
chemical_list: D005938:Glucocorticoids; D011241:Prednisone