title: One-pot thioether formation from S-nitrosothiols.
abstract: Protein S-nitrosation is an important post-translational modification. However, the detection of S-nitrosation is still problematic because S-nitrosation products, that is, S-nitrosothiols, are unstable species. Here a new reaction which can selectively convert unstable S-nitrosothiols to stable thioethers in one-pot under very mild conditions is reported. This reaction has the potential to be applied in the detection of protein S-nitrosation.
authors.affiliation: Department of Chemistry, Washington State University, Pullman, Washington 99164, USA.
authors.forename: Dehui
authors.initials: D
authors.lastname: Zhang
authors.forename: Nelmi O
authors.initials: NO
authors.lastname: Devarie-Baez
authors.forename: Jia
authors.initials: J
authors.lastname: Pan
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Ming
authors.initials: M
authors.lastname: Xian
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry; D015394:Molecular Structure; D026403:S-Nitrosothiols / Q000737:chemistry*; D013440:Sulfides / Q000138:chemical synthesis*
chemical_list: D000498:Allyl Compounds; D004220:Disulfides; D026403:S-Nitrosothiols; D013440:Sulfides