title: Exaggerated blood pressure response to exercise--a new portent of masked hypertension.
abstract: Masked hypertension (MHT) is a popular entity with increased risk of developing sustained hypertension, heart attack, stroke, and death. Subjects have normal blood pressure (BP) at office but elevated values at night so it is difficult to diagnose. Exaggerated blood pressure response to exercise (EBPR) is also a predictor of future hypertension. To investigate the relationship between these two entities, we evaluated 61 normotensive subjects with EBPR. The subjects underwent 24-h ambulatory blood pressure monitoring (ABPM). The prevalence of masked hypertension among subjects with EBPR was 41%. Body mass index (BMI), non-high density lipoprotein (HDL) cholesterol, diastolic blood pressure (DBP) at peak exercise and recovery, nondipping DBP pattern, and elevated early morning average BPs were associated with masked hypertension. In multivariate logistic regression analysis, the DBP measured at peak exercise was detected as an independent predictor of MHT in subjects with EBPR. Subjects with abnormally elevated BP during exercise are prone to MHT, necessitate medical assessment and close follow-up for hypertension.
authors.affiliation: Department of Cardiology, Selcuk University, Meram School of Medicine Hospital, Konya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kayrak
authors.forename: Ahmet
authors.initials: A
authors.lastname: Bacaksiz
authors.forename: Mehmet Akif
authors.initials: MA
authors.lastname: Vatankulu
authors.forename: Selim S
authors.initials: SS
authors.lastname: Ayhan
authors.forename: Zeynettin
authors.initials: Z
authors.lastname: Kaya
authors.forename: Hatem
authors.initials: H
authors.lastname: Ari
authors.forename: Osman
authors.initials: O
authors.lastname: Sonmez
authors.forename: Hasan
authors.initials: H
authors.lastname: Gok
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm; D003971:Diastole; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013599:Systole