title: Meta nitration of thiacalixarenes.
abstract: Nitration of thiacalix[4]arene, immobilized in the 1,3-alternate conformation, leads regioselectively to meta-substituted products. Depending on the reaction conditions, mono- and dinitro-derivatives can be isolated in acceptable yields. This unique substitution pattern is inaccessible in classical calixarene chemistry, and yields inherently chiral compounds, which makes thiacalixarenes very attractive as building blocks or molecular scaffolds.
authors.affiliation: Department of Organic Chemistry, Prague Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic.
authors.forename: Ondrej
authors.initials: O
authors.lastname: Kundrat
authors.forename: Jan
authors.initials: J
authors.lastname: Kroupa
authors.forename: Stanislav
authors.initials: S
authors.lastname: Böhm
authors.forename: Jan
authors.initials: J
authors.lastname: Budka
authors.forename: Vaclav
authors.initials: V
authors.lastname: Eigner
authors.forename: Pavel
authors.initials: P
authors.lastname: Lhotak