title: Incurred sample reanalysis: enhancing the Bland-Altman approach with tolerance intervals.
abstract: This article describes the need for incurred sample reanalysis and suggests that the combination of a Bland-Altman plot and tolerance intervals can provide a visual evaluation of method performance. It also shows how the proposed combination is a tool that may be of value in determining minimum sample size. An example dataset is worked through in its entirety so that a reader unfamiliar with the topic can gain sufficient information to analyze their own data. Related topics include the generation of 66.7% tolerance factors, comparison of mean-normalized and log differences and the use of probability plots to evaluate error distributions. The suggestions presented in this article are meant to be a continuation of the ongoing incurred sample reanalysis discussion and, as such, further comment is invited.
authors.affiliation: Indigo BioSystems, 20 East 91st Street, Indianapolis, IN 46240, USA.
authors.forename: Fred E
authors.initials: FE
authors.lastname: Lytle
authors.forename: Randall K
authors.initials: RK
authors.lastname: Julian
authors.forename: Amy M
authors.initials: AM
authors.lastname: Tabert
mesh_terms: D002138:Calibration; D002623:Chemistry Techniques, Analytical / Q000592:standards* / Q000706:statistics & numerical data*; D006801:Humans; D015203:Reproducibility of Results; D018401:Sample Size