title: The use of a membrane and/or a bone graft may not improve the effects of enamel matrix derivatives in infrabony defects.
abstract: BACKGROUND
  Do bone grafts or barrier membranes provide additional treatment effects for intrabony lesions treated with enamel matrix derivatives? A network meta-analysis of randomized controlled trails. Tu Y-K, Woolston A, Faggion CM Jr. J Clin Periodontol 2010;37:59-79.
  
  
  METHODS
  Simone Verardi, DDS, MSD.
  
  
  OBJECTIVE
  Do membranes and bone grafts improve the outcomes in the treatment of intrabony defects when they are used in combination with enamel matrix derivatives?
  
  
  BACKGROUND
  Government: Higher Education Funding Council for England (HEFCE) and United Kingdom Research Council Fellowship.
  
  
  METHODS
  Systematic review with meta-analysis of data.
  
  
  METHODS
  Level 2: Limited-quality patient-oriented evidence.
  
  
  METHODS
  Grade B: Inconsistent or limited-quality patient-oriented evidence.
authors.affiliation: Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA. sverardi@u.washington.edu
authors.forename: Simone
authors.initials: S
authors.lastname: Verardi