title: [Clinical implications of endoscopically suspected eosinophilic esophagitis].
abstract: OBJECTIVE
  We aimed to determine the concordance rate and clinical predictors of eosinophilic esophagitis (EoE) in patients with endoscopically suspected eosinophilic esophagitis (ESEoE) findings.
  
  
  METHODS
  From June 2006 to December 2009 in Gangnam Severance Hospital, we prospectively enrolled the patients of "endoscopically suspected eosinophilic esophagitis (ESEoE)", and then we retrospectively reviewed and analyzed clinical features and endoscopic findings.
  
  
  RESULTS
  We found 17 patients of ESEoE, and 5 of them were finally confirmed as an EoE by histology (diagnostic concordance rate 29.4%). We added two more patients previously diagnosed as EoE and compared patients of EoE＋ (n=7) with EoE- (n=12). Mean age was 56.0 (range 36-70) and 51.0 (range 36-68) years old, respectively. In EoE＋ group, there were 5 males and 2 females and 6 males and 6 females in EoE- group. The symptoms of EoE＋ patients were dysphagia (n=5), food impaction (n=3), foreign body sensation in esophagus (n=2), chest pain (n=1), and heartburn (n=1). EoE- patients complained food impaction (n=5), heartburn (n=4), chest pain (n=2), foreign body sensation in esophagus (n=2), and dysphagia (n=1). The endoscopic findings of EoE＋ patients were furrows (n=6), rings (n=5), exudates or nodules (n=3), and friability (n=1). EoE- patients showed rings (n=10) and furrows(n=7). Univariative analysis showed that 'a symptom of dysphagia', 'presence of exudates or nodules', 'more than 2 suggestive endoscopic findings' were significantly different between two groups.
  
  
  CONCLUSIONS
  In ESEoE, diagnostic concordance rate was 29.4%. In addition, 'symptom of dysphagia', 'exudates or nodules', '≥ endoscopic findings' are more suggestive of EoE in ESEoE patients.
authors.affiliation: Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Keun Man
authors.initials: KM
authors.lastname: Lee
authors.forename: Hyun Chul
authors.initials: HC
authors.lastname: Lim
authors.forename: Jie Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Yoon
authors.forename: Hyo Jin
authors.initials: HJ
authors.lastname: Park
authors.forename: Sang In
authors.initials: SI
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D002637:Chest Pain / Q000209:etiology; D003680:Deglutition Disorders / Q000209:etiology; D016099:Endoscopy, Gastrointestinal; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D004804:Eosinophils / Q000276:immunology; D005260:Female; D006356:Heartburn / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies