title: Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols.
abstract: An (S)-selective dynamic kinetic resolution of secondary alcohols, employing a mutated variant of Candida antarctica lipase B (CalB) gave products in 84-88% yield and in 90-97% ee.
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91, Stockholm, Sweden.
authors.forename: Karin
authors.initials: K
authors.lastname: Engström
authors.forename: Michaela
authors.initials: M
authors.lastname: Vallin
authors.forename: Per-Olof
authors.initials: PO
authors.lastname: Syrén
authors.forename: Karl
authors.initials: K
authors.lastname: Hult
authors.forename: Jan-E
authors.initials: JE
authors.lastname: Bäckvall
mesh_terms: D000438:Alcohols / Q000737:chemistry* / Q000378:metabolism; D002175:Candida / Q000737:chemistry / Q000201:enzymology* / Q000235:genetics; D005656:Fungal Proteins; D007700:Kinetics; D008049:Lipase / Q000235:genetics / Q000378:metabolism*; D015394:Molecular Structure; D009154:Mutation
chemical_list: D000438:Alcohols; D005656:Fungal Proteins; D008049:Lipase; C431349:lipase B, Candida antarctica