title: Serum 25-hydroxyvitamin D concentration and physical function in adult men.
abstract: OBJECTIVE
  Recent reports suggest that vitamin D status influences musculoskeletal health; yet, there are limited data in adult men. This study investigated whether serum 25-hydroxyvitamin D [25(OH)D] concentration was associated with lean body mass, muscle strength and physical performance in men.
  
  
  METHODS
  Population-based, observational survey.
  
  
  METHODS
  1219 black, Hispanic and white randomly selected men aged 30-79 years from the Boston Area Community Health/Bone Survey.
  
  
  METHODS
  Lean body mass by dual-energy X-ray absorptiometry, hand grip strength, a composite physical function score (chair stand and walking speed), 25(OH)D, parathyroid hormone (PTH), testosterone, age, race, body mass index, socioeconomic status, education, smoking, arthritis, self-reported health, calcium intake, physical activity.
  
  
  RESULTS
  The distributions of serum 25(OH)D quartiles differed by race/ethnicity, education and smoking status. After adjustment for multiple lifestyle factors, serum 25(OH)D was not related to lean body mass, grip strength or the composite physical function score (all P>0.20). There was no variation in the associations between 25(OH)D level and outcomes by race/ethnicity. The relationship between PTH and the outcomes revealed similar results.
  
  
  CONCLUSIONS
  In this population-based sample of adult men with a broad age range, there was no association between serum 25(OH)D concentration and lean body mass, muscle strength and physical function after controlling for multiple lifestyle factors.
authors.affiliation: Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center, Boston, MA, USA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Ceglia
authors.forename: Gretchen R
authors.initials: GR
authors.lastname: Chiu
authors.forename: Susan S
authors.initials: SS
authors.lastname: Harris
authors.forename: Andre B
authors.initials: AB
authors.lastname: Araujo
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D000368:Aged; D015992:Body Mass Index; D001900:Boston; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D053580:Muscle Strength / Q000502:physiology*; D010281:Parathyroid Hormone / Q000097:blood; D011597:Psychomotor Performance / Q000502:physiology*; D012923:Social Class; D013739:Testosterone / Q000097:blood; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D044465:White People / Q000706:statistics & numerical data
chemical_list: D010281:Parathyroid Hormone; D014807:Vitamin D; D013739:Testosterone; C104450:25-hydroxyvitamin D