title: Necrotizing sialometaplasia of the parotid gland in a dog.
abstract: Necrotizing sialometaplasia (NS) is a self-limiting, benign, ischemic, inflammatory disease that is most often described in the submandibular glands of dogs, with clinical and histologic features that resemble malignancy. Unilateral swelling of the parotid salivary gland in a 7-year-old Cocker Spaniel dog was diagnosed as NS. The dog also had otitis externa on the same side as the parotid gland lesions. The main histologic features were included lobular necrosis of salivary tissue; fibrinoid necrosis of some arteries; marked squamous metaplasia of duct and/or acinar epithelium, with intercellular bridge formation; preservation of salivary lobular morphology; and variable inflammation and fibrosis. Etiologic factors for NS in both humans and animals remain obscure.
authors.affiliation: Pathodiagnostic Laboratory, Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service, #480, Anyang 6dong, Anyang, Gyeonggi-do 430-824, Republic of Korea.
authors.forename: Ha-Young
authors.initials: HY
authors.lastname: Kim
authors.forename: Gye-Hyeong
authors.initials: GH
authors.lastname: Woo
authors.forename: You-Chan
authors.initials: YC
authors.lastname: Bae
authors.forename: Yeon-Hee
authors.initials: YH
authors.lastname: Park
authors.forename: Yi-Seok
authors.initials: YS
authors.lastname: Joo
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004285:Dogs; D008297:Male; D010306:Parotid Gland / Q000473:pathology*; D012797:Sialometaplasia, Necrotizing / Q000175:diagnosis / Q000473:pathology / Q000601:surgery / Q000662:veterinary*