title: Linking Klotho, Nrf2, MAP kinases and aging.
authors.affiliation: Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089, USA.
authors.forename: Priya
authors.initials: P
authors.lastname: Balasubramanian
authors.forename: Valter D
authors.initials: VD
authors.lastname: Longo
mesh_terms: D000375:Aging / Q000502:physiology*; D019588:Aging, Premature / Q000235:genetics / Q000378:metabolism; D000818:Animals; D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D005966:Glucuronidase / Q000235:genetics / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D000090265:Klotho Proteins; D048848:MAP Kinase Kinase Kinase 5 / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D051267:NF-E2-Related Factor 2 / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism; D013879:Thioredoxins / Q000378:metabolism; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism*
chemical_list: D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors; C467200:Foxo1 protein, mouse; D007328:Insulin; D051267:NF-E2-Related Factor 2; C495636:Nfe2l2 protein, mouse; D017382:Reactive Oxygen Species; D013879:Thioredoxins; D007334:Insulin-Like Growth Factor I; D013482:Superoxide Dismutase; D048051:p38 Mitogen-Activated Protein Kinases; D048848:MAP Kinase Kinase Kinase 5; C482859:Map3k5 protein, mouse; D005966:Glucuronidase; D000090265:Klotho Proteins