title: The study of core-shell molecularly imprinted polymers of 17β-estradiol on the surface of silica nanoparticles.
abstract: In this paper, highly selective core-shell molecularly imprinted polymers of 17β-estradiol on the surface of silica nanoparticles (SiO(2)@E2-MIPs) were prepared. The SiO(2)@E2-MIPs were characterized by Fourier transform infrared spectrometer (FT-IR), transmission electron microscope (TEM), dynamic adsorption and static adsorption tests. The sorption capacity of the SiO(2)@E2-MIPs were nearly 5 times that of the non-imprinted polymers (NIPs), and it only took 25 min to achieve the sorption equilibrium. It indicated that the SiO(2)@E2-MIPs exhibited a high selectivity, large adsorption capacity and fast kinetics. When the SiO(2)@E2-MIPs were used as dispersive solid-phase extraction (dSPE) absorbents to selectively enrich and determine estrogens in duck feed, the average recoveries of E2 and estriol (E3) were higher than 96.74% and 72.07%, respectively, and the relative standard deviations (RSD) of E2 and E3 were less than 1.61% and 3.28%, respectively. The study provides an effective method for the separation and enrichment of estrogens in the complex matrix samples by the SiO(2)@E2-MIPs.
authors.affiliation: School of Pharmacy, Nanjing Medical University, Hanzhong Road, Nanjing 210029, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.forename: Lihua
authors.initials: L
authors.lastname: Yuan
authors.forename: Meijuan
authors.initials: M
authors.lastname: Ding
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.forename: Feng
authors.initials: F
authors.lastname: Ren
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Shuhu
authors.initials: S
authors.lastname: Du
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.forename: Xuemin
authors.initials: X
authors.lastname: Zhou
mesh_terms: D004958:Estradiol / Q000032:analysis* / Q000737:chemistry*; D015336:Molecular Probe Techniques / Q000295:instrumentation*; D015335:Molecular Probes / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D015335:Molecular Probes; D004958:Estradiol; D012822:Silicon Dioxide