title: Preparation of amphiphilic polymer-functionalized carbon nanotubes for low-protein-adsorption surfaces and protein-resistant membranes.
abstract: Multiwalled carbon nanotubes functionalized with poly(sulfone) (PSF) and poly(sulfobetaine methacrylate) (PSBMA) (MWNT-PSF/PSBMA) have been prepared through sequential atom transfer radical polymerization. The structure of MWNT-PSF/PSBMA hybrid has been characterized with FTIR, Raman spectroscopy, and high-resolution transmission electron microscopy. Incorporation of PSBMA chains to MWNTs introduces amphiphilic and protein-resistant properties to MWNT-PSF/PSBMA. Addition of 1 wt % MWNT-PSF/PSBMA to PSF films significantly improves their protein-resistant characteristic, as the composite films show a 4.4% of protein adsorption compared to poly(styrene) Petri dishes. The PSF/MWNT-PSF/PSBMA composite has been applied to prepare antifouling ultrafiltration membranes for protein separation. This work demonstrates an effective and convenient approach to prepare low-protein-adsorption surfaces and antifouling membranes.
authors.affiliation: Department of Chemical Engineering and R&D Center for Membrane Technology, Chung Yuan Christian University, Chungli, Taoyuan 32023, Taiwan.
authors.forename: Ying-Ling
authors.initials: YL
authors.lastname: Liu
authors.forename: Yung
authors.initials: Y
authors.lastname: Chang
authors.forename: Yu-Hsun
authors.initials: YH
authors.lastname: Chang
authors.forename: Yu-Ju
authors.initials: YJ
authors.lastname: Shih
mesh_terms: D000327:Adsorption; D001665:Binding Sites; D003460:Crystallization / Q000379:methods; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D008566:Membranes; D008567:Membranes, Artificial; D008689:Methacrylates / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D008567:Membranes, Artificial; D008689:Methacrylates; D037742:Nanotubes, Carbon; D011108:Polymers; D011506:Proteins; D013450:Sulfones; C521589:sulfobetaine methacrylate polymer; C017662:polysulfone P 1700