title: [Macrocystic serous adenoma of the pancreas: a report of 5 cases].
abstract: OBJECTIVE
  To investigate the diagnosis and treatment of macrocystic serous adenoma of the pancreas (MSAP).
  
  
  METHODS
  The clinical data of 5 patients with MSAP treated from October 1999 to October 2009 were retrospectively analyzed. There were 5 female and 1 male.
  
  
  RESULTS
  Of the 5 patients, 3 patients presented with abdominal pain and fullness, 1 patient with jaundice, 1 patient with asymptomatic. Ultrasonography and CT could manifest macrocystic lesion of the pancreas; all the lesion showed a well-defined border, internal septations, enhanced cyst walls, with no intramural (mural) nodule and papillary projections; the wall was smooth and thin in 4 cases; irregular lobulation could be observed in 3 cases, round or oval in 2 cases; 2 cases had pancreatic duct dilatation, 1 case had biliary duct dilatation. The tumors located in the pancreatic body and tail in 3 cases, the tumors located the pancreatic head in 2 cases. The sizes of the tumors ranged from 6.5 cm to 13.0 cm (mean, 8.8 cm). Five patients all accepted surgical intervention. The main postoperative complication was pancreatic fistula (2 cases); all the fistula was cured. Recurrence or metastasis were not found in 5 patient followed up postoperatively from 8 to 35 months.
  
  
  CONCLUSIONS
  MSAP has no specific symptoms. The imaging appearance of MSAP is similar to mucinous cystic neoplasm of the pancreas. The tumor can gradually grow up and produce compression symptoms. MSAP can be cured by complete resection.
authors.affiliation: Department of Pancreatic and Gastroenterologic Surgery, the First Affiliated Hospital, China Medical University, Shenyang, China.
authors.forename: Yan-liang
authors.initials: YL
authors.lastname: Wang
authors.forename: Ke-jian
authors.initials: KJ
authors.lastname: Guo
authors.forename: Mei-fen
authors.initials: MF
authors.lastname: Zhao
authors.forename: Shao-wei
authors.initials: SW
authors.lastname: Song
authors.forename: Yuan-hong
authors.initials: YH
authors.lastname: Xu
authors.forename: Gang
authors.initials: G
authors.lastname: Ma
mesh_terms: D000328:Adult; D018293:Cystadenoma, Serous / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D012189:Retrospective Studies