title: Influence of rotary blood pumps over preload recruitable stroke work.
abstract: When recovery of the cardiac function is detected in assisted hearts, the ventricular assist device can be removed. Due to the invasiveness of the surgical procedure, an accurate assessment of cardiac function is fundamental for the treatment success. The main challenge for the detection of cardiac function during assistance is to know whether the cardiac function index represents the cardiac function after pump removal independently of the pump assist rate. Therefore in this paper we present an evaluation of the influence of the pump over the slope of the preload recruitable stroke work, a cardiac function index. Analyzing data from four acute animal experiments, we found that the pump affects the stroke work, which could be corrected by the end diastolic volume. However, the data set examined was limited and further investigation is necessary.
authors.affiliation: Graduate School of Biomedical Engineering, Tohoku University, 6-6-05, Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan. telma@yoshizawa.ecei.tohoku-ac.jp
authors.forename: Telma Keiko
authors.initials: TK
authors.lastname: Sugai
authors.forename: Akira
authors.initials: A
authors.lastname: Tanaka
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshizawa
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Baba
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yambe
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Nitta
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D004867:Equipment Design; D005260:Female; D006041:Goats; D006321:Heart / Q000033:anatomy & histology / Q000502:physiology*; D006333:Heart Failure / Q000628:therapy*; D006339:Heart Rate; D006353:Heart-Assist Devices; D006801:Humans; D011433:Propranolol / Q000494:pharmacology; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D018754:Ventricular Dysfunction / Q000628:therapy; D016277:Ventricular Function, Left
chemical_list: D000889:Anti-Arrhythmia Agents; D011433:Propranolol