title: Reactions of nitroxides. Part X: antifungal activity of selected sulfur and selenium derivatives of 2,2,6,6-tetramethylpiperidine.
abstract: The antifungal activity of nitroxyl radicals-derivatives of 2,2,6,6-tetramethylpiperidine-1-oxyl with reactive substituents 4-isothiocyanato-, 4-isocyano-, and 4-isoselenocyanato- and of N-formyl-, N-thioformyl-, N-selenoformyl-derivatives of 2,2,6,6-tetramethylpiperidine was investigated. Those of the above compounds, which contain a sulfur or selenium atom are the most active against four fungus plant patogens: Botrytiscinerea, Fusariumculmorum, Phytophthoracactorum, Rhizoctoniasolani. 4-Isoselenocyanato-2,2,6,6-tetramethylpiperidine-1-oxyl proved to be the most active compound.
authors.affiliation: Institute of Industrial Organic Chemistry, Annopol 6, 03-236 Warsaw, Poland. zakrzewski@ipo.waw.pl
authors.forename: Jerzy
authors.initials: J
authors.lastname: Zakrzewski
authors.forename: Maria
authors.initials: M
authors.lastname: Krawczyk
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D020171:Botrytis / Q000187:drug effects; D003497:Cyclic N-Oxides / Q000737:chemistry*; D005670:Fusarium / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009589:Nitrogen Oxides / Q000737:chemistry*; D010838:Phytophthora / Q000187:drug effects; D012232:Rhizoctonia / Q000187:drug effects; D012643:Selenium / Q000737:chemistry* / Q000494:pharmacology; D013113:Spin Labels; D013455:Sulfur / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D003497:Cyclic N-Oxides; D009589:Nitrogen Oxides; D013113:Spin Labels; D013455:Sulfur; C039900:nitroxyl; D012643:Selenium; C001803:tempol