title: Introduction of β-cyclodextrin into poly(aspartic acid) matrix for adsorption and time-release of ibuprofen.
abstract: Biodegradable copolymers with molecule inclusion ability was prepared by introduction of β-cyclodextrin into poly(aspartic acid) matrices. The ibuprofen loading and dissolution properties of poly(aspartic acid)-β-cyclodextrin were investigated.
authors.affiliation: UNILAB, State Key Lab of Chemical Engineering, East China University of Science and Technology, Shanghai, 200237, PR China.
authors.forename: Zhao-Yang
authors.initials: ZY
authors.lastname: Sun
authors.forename: Ming-Xing
authors.initials: MX
authors.lastname: Shen
authors.forename: An-Wen
authors.initials: AW
authors.lastname: Yang
authors.forename: Cong-Qiang
authors.initials: CQ
authors.lastname: Liang
authors.forename: Nan
authors.initials: N
authors.lastname: Wang
authors.forename: Gui-Ping
authors.initials: GP
authors.lastname: Cao
mesh_terms: D000327:Adsorption; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000737:chemistry*; D007052:Ibuprofen / Q000008:administration & dosage* / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D012995:Solubility; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D003692:Delayed-Action Preparations; D010455:Peptides; D047392:beta-Cyclodextrins; C017645:polyaspartate; C031215:betadex; D007052:Ibuprofen