title: Symptomatic progression of asymptomatic rotator cuff tears: a prospective study of clinical and sonographic variables.
abstract: BACKGROUND
  The purposes of this study were to identify changes in tear dimensions, shoulder function, and glenohumeral kinematics when an asymptomatic rotator cuff tear becomes painful and to identify characteristics of individuals who develop pain compared with those who remain asymptomatic.
  
  
  METHODS
  A cohort of 195 subjects with an asymptomatic rotator cuff tear was prospectively monitored for pain development and examined annually for changes in various parameters such as tear size, fatty degeneration of the rotator cuff muscle, glenohumeral kinematics, and shoulder function. Forty-four subjects were found to have developed new pain, and the parameters before and after pain development were compared. The forty-four subjects were then compared with a group of fifty-five subjects who remained asymptomatic over a two-year period.
  
  
  RESULTS
  With pain development, the size of a full-thickness rotator cuff tear increased significantly, with 18% of the full-thickness tears showing an increase of >5 mm, and 40% of the partial-thickness tears had progressed to a full-thickness tear. In comparison with the assessments made before the onset of pain, the American Shoulder and Elbow Surgeons scores for shoulder function were significantly decreased and all measures of shoulder range of motion were decreased except for external rotation at 90° of abduction. There was an increase in compensatory scapulothoracic motion in relation to the glenohumeral motion during early shoulder abduction with pain development. No significant changes were found in external rotation strength or muscular fatty degeneration. Compared with the subjects who remained asymptomatic, the subjects who developed pain were found to have significantly larger tears at the time of initial enrollment.
  
  
  CONCLUSIONS
  Pain development in shoulders with an asymptomatic rotator cuff tear is associated with an increase in tear size. Larger tears are more likely to develop pain in the short term than are smaller tears. Further research is warranted to investigate the role of prophylactic treatment of asymptomatic shoulders to avoid the development of pain and loss of shoulder function.
authors.affiliation: Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Nathan A
authors.initials: NA
authors.lastname: Mall
authors.forename: H Mike
authors.initials: HM
authors.lastname: Kim
authors.forename: Jay D
authors.initials: JD
authors.lastname: Keener
authors.forename: Karen
authors.initials: K
authors.lastname: Steger-May
authors.forename: Sharlene A
authors.initials: SA
authors.lastname: Teefey
authors.forename: William D
authors.initials: WD
authors.lastname: Middleton
authors.forename: Georgia
authors.initials: G
authors.lastname: Stobbs
authors.forename: Ken
authors.initials: K
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D016009:Chi-Square Distribution; D015331:Cohort Studies; D016001:Confidence Intervals; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D016059:Range of Motion, Articular / Q000502:physiology*; D017006:Rotator Cuff / Q000000981:diagnostic imaging / Q000503:physiopathology; D000070636:Rotator Cuff Injuries; D020069:Shoulder Pain / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D018709:Statistics, Nonparametric; D013314:Stress, Mechanical; D013708:Tendon Injuries / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013997:Time Factors; D014463:Ultrasonography