title: Development and validation of a magneto-hydrodynamic solver for blood flow analysis.
abstract: The objective of this study was to develop a numerical solver to calculate the magneto-hydrodynamic (MHD) signal produced by a moving conductive liquid, i.e. blood flow in the great vessels of the heart, in a static magnetic field. We believe that this MHD signal is able to non-invasively characterize cardiac blood flow in order to supplement the present non-invasive techniques for the assessment of heart failure conditions. The MHD signal can be recorded on the electrocardiogram (ECG) while the subject is exposed to a strong static magnetic field. The MHD signal can only be measured indirectly as a combination of the heart's electrical signal and the MHD signal. The MHD signal itself is caused by induced electrical currents in the blood due to the moving of the blood in the magnetic field. To characterize and eventually optimize MHD measurements, we developed a MHD solver based on a finite element code. This code was validated against literature, experimental and analytical data. The validation of the MHD solver shows good agreement with all three reference values. Future studies will include the calculation of the MHD signals for anatomical models. We will vary the orientation of the static magnetic field to determine an optimized location for the measurement of the MHD blood flow signal.
authors.affiliation: Center for Devices and Radiological Health, FDA, Silver Spring, MD, USA. wolfgang.kainz@fda.hhs.gov
authors.forename: W
authors.initials: W
authors.lastname: Kainz
authors.forename: J
authors.initials: J
authors.lastname: Guag
authors.forename: S
authors.initials: S
authors.lastname: Benkler
authors.forename: D
authors.initials: D
authors.lastname: Szczerba
authors.forename: E
authors.initials: E
authors.lastname: Neufeld
authors.forename: V
authors.initials: V
authors.lastname: Krauthamer
authors.forename: J
authors.initials: J
authors.lastname: Myklebust
authors.forename: H
authors.initials: H
authors.lastname: Bassen
authors.forename: I
authors.initials: I
authors.lastname: Chang
authors.forename: N
authors.initials: N
authors.lastname: Chavannes
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: M
authors.initials: M
authors.lastname: Sarntinoranont
authors.forename: N
authors.initials: N
authors.lastname: Kuster
mesh_terms: D001011:Aorta / Q000502:physiology; D001775:Blood Circulation; D006801:Humans; D057446:Hydrodynamics; D008280:Magnetics; D008954:Models, Biological