title: Influence of Chlorella powder intake during swimming stress in mice.
abstract: We used the forced swimming test to investigate the influence of Chlorella powder intake during muscle stress training in mice. After day 14, swimming time was about 2-fold longer for Chlorella intake mice than for control swimming mice. Microarray analysis revealed that the global gene expression profile of muscle from the Chlorella intake mice was similar to that of muscle from the intact (non-swimming) mice, and the profile of these two groups differed from that of the control (swimming) mice. Gene ontology and pathway analyses of gene expression data showed that oxidoreductase activity and the leukotriene synthesis pathway were repressed in the Chlorella intake mice following the swimming test. In addition, measurements of free fatty acids, glucose, triglycerides, and lactic acid in the blood of Chlorella intake mice were higher than that of control mice. These findings suggest that metabolism in tissues is altered by Chlorella intake.
authors.affiliation: Sun Chlorella Corp., Research and Development Department, Karasuma-dori, Gojo, Shimogyo-ku, Kyoto 600-8177, Japan. mizoguchi@sunchlorella.co.jp
authors.forename: Toru
authors.initials: T
authors.lastname: Mizoguchi
authors.forename: Yukari
authors.initials: Y
authors.lastname: Arakawa
authors.forename: Michie
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Masaki
authors.initials: M
authors.lastname: Fujishima
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002708:Chlorella; D005230:Fatty Acids, Nonesterified / Q000097:blood / Q000378:metabolism; D020869:Gene Expression Profiling; D005947:Glucose / Q000378:metabolism; D019344:Lactic Acid / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000378:metabolism; D028321:Plant Preparations / Q000494:pharmacology*; D011208:Powders; D013312:Stress, Physiological / Q000187:drug effects* / Q000235:genetics; D013550:Swimming; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D028321:Plant Preparations; D011208:Powders; D014280:Triglycerides; D019344:Lactic Acid; D005947:Glucose