title: On-line enrichment and measurement of four halogenated phenols in water samples using pressure-assisted electrokinetic injection-tandem mass spectrometry.
abstract: A rapid and sensitive method using pressure-assisted electrokinetic injection (PAEKI) as the on-line sample enrichment technique and electrospray-tandem mass spectrometry as the monitor has been developed for the determination of four halogenated phenols, 2,4,6-trichlorophenol, 2,4-dichlorophenol, 2,3,4,6-tetrachlorophenol and tetrabromobisphenol A, in water samples. In 8-min of injection, the four halogenated phenols in water samples were enriched up to several thousand times. With the aid of a solid-phase extraction clean-up procedure, the method achieved a detection limit in the range of 7.4 to 37.1 ng L(-1) for the four phenols by multiple reaction monitoring in a negative mode. The overall recoveries for all four halogenated phenols in water samples were in the range of 68 to 114%. The good method repeatability has been demonstrated by the relative standard deviations (RSDs) of less than 10% for water samples spiked with standard mixtures. The four target phenols in all the water samples were below the detection limits.
authors.affiliation: Exposure and Biomonitoring Division, Health Canada, AL: 0800C, EHC, Tunney’s Pasture, Ottawa, Ontario, K1A 0K9, Canada.
authors.forename: Huijuan
authors.initials: H
authors.lastname: Zhang
authors.forename: Jiping
authors.initials: J
authors.lastname: Zhu
authors.forename: Yong-Lai
authors.initials: YL
authors.lastname: Feng
mesh_terms: D020374:Chromatography, Micellar Electrokinetic Capillary; D054879:Halogenation; D010636:Phenols / Q000032:analysis*; D011312:Pressure; D045483:Rivers / Q000737:chemistry*; D053719:Tandem Mass Spectrometry; D014874:Water Pollutants, Chemical / Q000737:chemistry*
chemical_list: D010636:Phenols; D014874:Water Pollutants, Chemical