title: Papillary carcinoma of the thyroglossal duct cyst: report of two cases.
abstract: OBJECTIVE
  To present two cases of papillary carcinoma of the thyroglossal duct cyst (TDC) and to report their management.
  
  
  METHODS
  Two patients, a 47-year-old woman and a 60-year-old man, were operated in 2006 and 2008 in the Department of Digestive and Metabolic Surgery of the "Jean Verdier" Hospital.
  
  
  RESULTS
  The diagnosis of papillary carcinoma was established after the pathological examination carried out on the thyroglossal duct cyst, after its complete surgical excision. A total thyroidectomy followed by a treatment by radioactive iodine and a substitutive hormonal therapy were carried out in the second time for one of the two patients. For the other patient, a total thyroidectomy followed by a substitute hormonal therapy, were achieved. The evolution was favorable, with a follow-up of four years for the first patient and two years for the second one.
  
  
  CONCLUSIONS
  Total thyroidectomy after the complete excision of the cyst is currently the recommended treatment for the papillary carcinoma of the TDC. It was shown that a latent thyroid cancer could develop even 15 years after the initial excision of the thyroglossal cyst. The treatment is curative in 95% of the cases.
  
  
  CONCLUSIONS
  Current treatment of papillary carcinoma of the thyroglossal duct cyst is well codified, allowing an excellent prognostic.
authors.affiliation: Department of Digestive and Metabolic Surgery, Jean Verdier Hospital, Bondy, Paris, France. adriana.torcivia@jvr.aphp.fr
authors.forename: Adriana
authors.initials: A
authors.lastname: Torcivia
authors.forename: C
authors.initials: C
authors.lastname: Polliand
authors.forename: Marianne
authors.initials: M
authors.lastname: Ziol
authors.forename: Fanny
authors.initials: F
authors.lastname: Dufour
authors.forename: G
authors.initials: G
authors.lastname: Champault
authors.forename: C
authors.initials: C
authors.lastname: Barrat
mesh_terms: D002291:Carcinoma, Papillary / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D013955:Thyroglossal Cyst / Q000473:pathology* / Q000628:therapy; D013963:Thyroid Hormones / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D013965:Thyroidectomy
chemical_list: D007457:Iodine Radioisotopes; D013963:Thyroid Hormones