title: Review: Aptamers in microfluidic chips.
abstract: This review, covering reports published from 2002 to August 2010, shows how aptamers have made significant contributions in the improvements of microfluidic chips for affinity extraction, separations and detections. Furthermore, microfluidic chip methods for studying aptamer-target interactions and performing aptamer selections have also been summarized. Accordingly, research vacancies and future development trends in these areas are discussed.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Changchun, Jilin 130022, China.
authors.forename: Yuanhong
authors.initials: Y
authors.lastname: Xu
authors.forename: Xiurong
authors.initials: X
authors.lastname: Yang
authors.forename: Erkang
authors.initials: E
authors.lastname: Wang
mesh_terms: D000818:Animals; D000906:Antibodies; D052157:Aptamers, Nucleotide / Q000032:analysis* / Q000737:chemistry*; D015415:Biomarkers / Q000032:analysis; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D056656:Lab-On-A-Chip Devices; D008024:Ligands; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D049329:Nanostructures; D015203:Reproducibility of Results; D052156:SELEX Aptamer Technique / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D000906:Antibodies; D052157:Aptamers, Nucleotide; D015415:Biomarkers; D008024:Ligands