title: CO2 laser improves 45S5 bioglass interaction with dentin.
abstract: Bioglass 45S5 is a bioactive glass that can create a layer of calcium-phosphate crystals on mineralized hard tissues. In this study, 45S5 bioglass was mixed with phosphoric acid and irradiated with CO(2) laser and examined as a possible aid in the treatment of dentin hypersensitivity. The dentinal surface modified by the aforementioned technique was chemically and micro-morphologically examined with a field emission scanning electron microscope (FE-SEM) equipped with an energy-dispersive x-ray spectroscope (EDS), and the crystalline structures of the examined dentinal surfaces were examined by x-ray diffraction (XRD). Moreover, the mechanical properties of the newly formed layer were examined by nanoindentation. The results showed that 45S5 bioglass could occlude the dentinal tubule orifices with calcium-phosphate crystals. The application of CO(2) laser potentially improved the mechanical organization of these crystals.
authors.affiliation: Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8549, Japan. drahmedbakry@gmail.com.
authors.forename: A S
authors.initials: AS
authors.lastname: Bakry
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Otsuki
authors.forename: A
authors.initials: A
authors.lastname: Sadr
authors.forename: K
authors.initials: K
authors.lastname: Yamashita
authors.forename: J
authors.initials: J
authors.lastname: Tagami
mesh_terms: D002130:Calcium Phosphates; D002516:Ceramics / Q000627:therapeutic use*; D018360:Crystallography, X-Ray; D003804:Dentin / Q000737:chemistry / Q000648:ultrastructure; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D055119:Elastic Modulus; D005898:Glass; D006244:Hardness; D006801:Humans; D054020:Lasers, Gas / Q000627:therapeutic use*; D008855:Microscopy, Electron, Scanning / Q000295:instrumentation; D013052:Spectrometry, X-Ray Emission; D014867:Water
chemical_list: D002130:Calcium Phosphates; D057133:Dentin Desensitizing Agents; C425330:bioactive glass 45S5; D014867:Water; C020243:calcium phosphate