title: [Comparison of the cut direction between gross finding, streoscopic finding, and pathologic mapping of endoscopic submucosal dissection Specimen].
abstract: OBJECTIVE
  The correct pathologic review is very important after endoscopic submucosal dissection. The cut direction of specimen should be the right angle of the closest area between the lesion and the lateral margin for the correct pathologic review. The aim of this study was to evaluate the concordance of the gross finding and stereoscopic finding compared to the pathologic mapping in the setting of the cut direction.
  
  
  METHODS
  Between December 2008 and May 2009, the objects were 48 specimens in 46 patients who were diagnosed with early gastric cancer and high grade adenoma after endoscopic submucosal dissection. The specimens were stained with hematoxylin and observed by the stereoscopy and analyzed by the image analysis system. The cut direction was divided by an angle of 45 degree based on the oral side of the specimen, and the cut directions of the gross finding, the stereoscopic finding, and the pathologic finding were compared.
  
  
  RESULTS
  The concordance of the gross finding in the setting of the cut direction was 68% (33/48), and the kappa value was 0.626, and the concordance of the stereoscopic finding in the setting of the cut direction was 87% (33/48), and the kappa value was 0.874. The accuracy of the gross finding was significantly lower than that of the stereoscopic finding in the setting of the cut direction (p<0.05).
  
  
  CONCLUSIONS
  The endoscopist needs the careful observation and close attention in the setting of the cut direction of the specimen by gross finding, and stereoscopic analysis may be a useful tool for decision of the cut direction.
authors.affiliation: Department of Internal Medicine, Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: Young Kwan
authors.initials: YK
authors.lastname: Cho
authors.forename: Joo Young
authors.initials: JY
authors.lastname: Cho
authors.forename: So Young
authors.initials: SY
authors.lastname: Jin
authors.forename: Won Young
authors.initials: WY
authors.lastname: Cho
authors.forename: Yoon Ho
authors.initials: YH
authors.lastname: Jung
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Lee
authors.forename: Hyun Gun
authors.initials: HG
authors.lastname: Kim
authors.forename: Jin Oh
authors.initials: JO
authors.lastname: Kim
authors.forename: Joon Seong
authors.initials: JS
authors.lastname: Lee
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000601:surgery; D004210:Dissection / Q000379:methods*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology* / Q000601:surgery; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery