title: [Muscle regeneration and the state of the thymus in adult rats under laser irradiation and alloplasty of the gastrocnemius muscles and diaphragm of newborn rats].
abstract: The regeneration of gastrocnemius muscles of adult rats under implantation conditions in areas of muscle tissue damage in newborn rats has been studied. Alloplasty was performed using minced gastrocnemius and diaphragm muscles, which differs at birth in animals by degree of differentiation. The rat-recipient area of alloplasty was subjected to He-Ne laser radiation before operation, with the aim of reducing the immune response to allogenic muscle tissue. It has been shown that the number of regenerating myofibers produced in implanted gastrocnemius muscles is more than in alloplants from diaphragms. However, the formation of cartilage, bone, and adipose tissue foci were observed in the alloplastic region throughout the whole regeneration period. After implantation of minced diaphragm muscles, cartilage nodes were observed only in 7-day regenerates. At the end of observation, in the first instance, the area of muscle trauma in adult rat muscles was replaced by adipose tissue, even in the case of initial laser irradiation. During the implantation of diaphragm muscles, the area of trauma was filled with regenerating muscle tissue.
authors.forename: N V
authors.initials: NV
authors.lastname: Buliakova
authors.forename: V S
authors.initials: VS
authors.lastname: Azarova
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D003964:Diaphragm; D006614:Hindlimb; D028022:Low-Level Light Therapy; D018482:Muscle, Skeletal / Q000293:injuries / Q000502:physiology / Q000528:radiation effects / Q000637:transplantation*; D051381:Rats; D012038:Regeneration / Q000528:radiation effects*; D013950:Thymus Gland / Q000276:immunology / Q000528:radiation effects*; D014184:Transplantation, Homologous; D014947:Wounds and Injuries / Q000532:radiotherapy / Q000601:surgery*