title: Disarming Clostridium difficile.
abstract: In this issue, Puriet al. (2010) present inhibitors that prevent the autocatalytic activation of the clostridial toxin TcdB in vivo. Their approach is likely to provide guidance for the development of novel drugs targeting virulence factors and thereby rendering bacterial pathogens innocuous.
authors.affiliation: Department of Chemistry, Center for Integrated Protein Science Munich (CIPS(M)), Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
authors.forename: Malte
authors.initials: M
authors.lastname: Gersch
authors.forename: Stephan A
authors.initials: SA
authors.lastname: Sieber