title: CDDO-Im, an antitumor molecule that also improves platetet production.
authors.forename: José L
authors.initials: JL
authors.lastname: Sardina
authors.forename: Guillermo
authors.initials: G
authors.lastname: López-Ruano
authors.forename: Beatriz
authors.initials: B
authors.lastname: Sánchez-Sánchez
authors.forename: Angel
authors.initials: A
authors.lastname: Hernández-Hernández
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D001792:Blood Platelets / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D041905:Erythroid Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D050982:GATA1 Transcription Factor / Q000378:metabolism; D050989:GATA2 Transcription Factor / Q000378:metabolism; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008533:Megakaryocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000378:metabolism; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D015398:Signal Transduction / Q000187:drug effects
chemical_list: C472829:1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole; D000970:Antineoplastic Agents; D050982:GATA1 Transcription Factor; D050989:GATA2 Transcription Factor; C494711:GATA2 protein, human; D007093:Imidazoles; D009828:Oleanolic Acid; C535150:MAPK1 protein, human; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3