title: Audiological manifestations in children and adults with AIDS.
abstract: BACKGROUND
  according to the literature, the incidence of hearing impairment in patients with HIV / AIDS might be caused by alterations in external, middle and / or internal ear.
  
  
  OBJECTIVE
  to characterize and to compare the results of audiological assessment and Auditory Brainstem Response in children and adults with AIDS.
  
  
  METHODS
  audiological and electrophysiological (Auditory Brainstem Response) assessment of hearing was carried out in 51 children and 22 adults with HIV/AIDS (research groups I and II, respectively) and in 50 healthy children and 25 healthy adults (control groups I and II, respectively). Participants ranged in age between 3 and 10 years (children) and between 18 and 50 years (adults).
  
  
  RESULTS
  the most frequent observed alteration for children with AIDS was related to the middle ear whereas for adults with AIDS it was related to the internal ear. Higher occurrence of abnormal results was observed for adults with AIDS as compared to children with AIDS.
  
  
  CONCLUSIONS
  children and adults with AIDS present alterations in audiological assessment and Auditory Brainstem Response. This suggests the involvement of peripheral and central auditory pathways. Findings of the present study emphasize the effectiveness of using electrophysiological hearing measures in order to better identify the brain injury level in patients with AIDS, besides allowing the monitoring of the development rate of the disease.
authors.affiliation: Fonoaudióloga, Universidade Federal de São Paulo, Brazil. cgmatas@usp.br
authors.forename: Carla Gentile
authors.initials: CG
authors.lastname: Matas
authors.forename: Valdete Alves Valentins dos
authors.initials: VA
authors.lastname: Santos Filha
authors.forename: Kleber Ramos de
authors.initials: KR
authors.lastname: Juan
authors.forename: Fernanda Rodrigues
authors.initials: FR
authors.lastname: Pinto
authors.forename: Isabela Crivellaro
authors.initials: IC
authors.lastname: Gonçalves
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D007758:Ear, Inner / Q000502:physiology*; D004432:Ear, Middle / Q000502:physiology*; D004594:Electrophysiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult