title: An inflammatory reaction surrounding molluscum contagiosum as possible manifestation of immune reconstitution inflammatory syndrome in HIV infection.
abstract: Highly active antiretroviral therapy can restore specific immune responses and control of microorganism infections in human immunodeficiency virus-positive patients. This immune recovery may cause an inflammatory reaction to microbial and autoimmune antigens known as immune reconstitution inflammatory syndrome. We describe a clinical case with an intense inflammatory response surrounding molluscum contagiosum after highly active antiretroviral therapy. The clinical and laboratory findings suggested that the reaction was due to immune reconstitution inflammatory syndrome occurring during a period of immune recovery in a child with acquired immune deficiency syndrome.
authors.affiliation: Division of Pediatric Dermatology, Department of Pediatrics, Federal University of Paraná (UFPR), Curitiba, Paraná, Brazil. rcarvalho50@hotmail.com
authors.forename: Vânia Oliveira
authors.initials: VO
authors.lastname: de Carvalho
authors.forename: Cristina Rodrigues
authors.initials: CR
authors.lastname: Cruz
authors.forename: Lúcia
authors.initials: L
authors.lastname: Noronha
authors.forename: Kerstin Taniguchi
authors.initials: KT
authors.lastname: Abagge
authors.forename: Hermênio Cavalcante
authors.initials: HC
authors.lastname: Lima
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D001706:Biopsy; D002648:Child; D003872:Dermatitis / Q000276:immunology* / Q000473:pathology / Q000821:virology*; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000276:immunology* / Q000473:pathology; D007121:Immunocompetence; D008297:Male; D008976:Molluscum Contagiosum / Q000276:immunology* / Q000473:pathology