title: Reeling in the catch: advancing cleavable linkers for proteomics.
abstract: In global proteomic applications that focus on the characterization of proteins that have been derivatized using bioorthogonal chemistry, a challenge persists in the release of labeled proteins from supports used for purification. In this issue, Yang and coworkers (2010) present a detailed study of the diazobenzene-cleavable linker system as an effective solution for proteomic studies.
authors.affiliation: Department of Chemistry, The University of Tennessee, 1420 Circle Drive, Knoxville, TN 37996, USA.
authors.forename: Meng M
authors.initials: MM
authors.lastname: Rowland
authors.forename: Michael D
authors.initials: MD
authors.lastname: Best