title: Application of 4-META/MMA-TBB resin for fixation of membrane to tooth in guided tissue regeneration in dog.
abstract: The aim of this study was to evaluate 4-META/MMA-TBB resin as an alternative to sling sutures for fixation of membrane to tooth in GTR in terms of its effect on tissue regeneration. Dehiscence periodontal defects were created in 6 dogs which were divided at random into two groups, 3 dogs in each group: an experimental group, in which non-absorbable or absorbable membrane was fixed to the teeth with 4-META/MMA-TBB resin; and a control group, in which sling sutures were applied to fix the two types of membrane. Histologic and histometric evaluation was carried out at 8 weeks post-operatively to determine healing response in each group. Both methods of achieving membrane fixation to tooth were effective in inhibiting epithelial migration and encouraging formation of regenerated periodontal tissues around the root surfaces. These results suggest that 4-META/MMA-TBB resin is as effective as sling sutures in achieving membrane fixation in GTR and is, moreover, easier to apply.
authors.affiliation: Department of Periodontology, Tokyo Dental College, Chiba, Japan. tomitas@tdc.ac.jp
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Tomita
authors.forename: Shigeki
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Shibukawa
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kaneko
authors.forename: Shoichi
authors.initials: S
authors.lastname: Miyakoshi
authors.forename: Masaki
authors.initials: M
authors.lastname: Shimono
authors.forename: Satoru
authors.initials: S
authors.lastname: Yamada
mesh_terms: D020341:Absorbable Implants; D000134:Acid Etching, Dental; D016301:Alveolar Bone Loss / Q000601:surgery; D000539:Alveolar Process / Q000473:pathology; D000818:Animals; D001641:Bicuspid / Q000601:surgery*; D001896:Boron Compounds / Q000627:therapeutic use*; D003739:Dental Cementum / Q000473:pathology; D012534:Dental Scaling; D004285:Dogs; D004846:Epithelial Attachment / Q000473:pathology; D005881:Gingiva / Q000473:pathology; D005882:Gingival Diseases / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D008297:Male; D008567:Membranes, Artificial; D008689:Methacrylates / Q000627:therapeutic use*; D008768:Methylmethacrylates / Q000627:therapeutic use*; D008855:Microscopy, Electron, Scanning; D011138:Polytetrafluoroethylene; D011897:Random Allocation; D019279:Resin Cements / Q000627:therapeutic use*; D016745:Root Planing; D013499:Surface Properties; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000627:therapeutic use*; D019237:Tooth Cervix / Q000473:pathology; D014945:Wound Healing / Q000502:physiology
chemical_list: D001896:Boron Compounds; D008567:Membranes, Artificial; D008689:Methacrylates; D008768:Methylmethacrylates; D019279:Resin Cements; D014014:Tissue Adhesives; D011138:Polytetrafluoroethylene; C049495:Super-bond