title: Lipid effects of endocrine medications.
abstract: Various alterations of lipid homeostasis have a significant role in the pathophysiology of the artherosclerotic process. The effects of usual lipid-lowering agents such as statins, fibrates, or niacin are well known, but other endocrine therapeutic agents could also affect the blood levels of various lipoproteins and, in turn, influence atheroma formation. In this review, we attempt to summarize the effect of several hormonal and non-hormonal endocrine agents on lipid metabolism, including insulin, thyroid hormone, sex hormones, glucocorticoids, growth hormone, and several anti-diabetic agents.
authors.affiliation: Department of Medicine, University of Illinois at Chicago, 1819 W. Polk Street, M/C 797, Chicago, IL, USA. danmih@uic.edu
authors.forename: Dan V
authors.initials: DV
authors.lastname: Mihailescu
authors.forename: Avni
authors.initials: A
authors.lastname: Vora
authors.forename: Theodore
authors.initials: T
authors.lastname: Mazzone
mesh_terms: D008078:Cholesterol, LDL / Q000378:metabolism*; D050171:Dyslipidemias / Q000150:complications / Q000378:metabolism; D004700:Endocrine System Diseases / Q000150:complications / Q000188:drug therapy*; D006727:Hormone Antagonists / Q000009:adverse effects / Q000493:pharmacokinetics; D006728:Hormones / Q000009:adverse effects / Q000493:pharmacokinetics; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects*
chemical_list: D008078:Cholesterol, LDL; D006727:Hormone Antagonists; D006728:Hormones