title: Habitual snoring and asthma comorbidity among pregnant women.
abstract: BACKGROUND
  Obstructive sleep apnea (OSA) or habitual snoring and asthma are known comorbid conditions in men and non-pregnant women. This comorbidity has not been evaluated among pregnant women. We assessed the habitual snoring-asthma relationship among pregnant women.
  
  
  METHODS
  A cohort of women (N = 1335) were interviewed during pregnancy, and we ascertained participants' asthma status and collected information about habitual snoring, before and during pregnancy. Logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).
  
  
  RESULTS
  Compared with non-asthmatics, the adjusted OR among asthmatics for snoring before pregnancy was 2.13 (95% CI 1.10-4.12). The odds of snoring during early pregnancy was 1.79-fold (OR = 1.79; 95% C; 1.07-3.01). Associations were more pronounced among overweight (≥ 25 kg/m(2)) asthmatics (OR = 5.39; 95% CI 2.27-12.75).
  
  
  CONCLUSIONS
  We report a cross-sectional association of habitual snoring and asthma among pregnant women. If confirmed, pregnant asthmatics may benefit from more vigilant screening and management of OSA or habitual snoring during pregnancy.
authors.affiliation: Center for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA. mwilliam@uw.edu
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Williams
authors.forename: Bizu
authors.initials: B
authors.lastname: Gelaye
authors.forename: Chunfang
authors.initials: C
authors.lastname: Qiu
authors.forename: Neway
authors.initials: N
authors.lastname: Fida
authors.forename: Swee
authors.initials: S
authors.lastname: May Cripe
mesh_terms: D001249:Asthma / Q000150:complications*; D005260:Female; D006801:Humans; D016017:Odds Ratio; D050177:Overweight / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications; D012913:Snoring / Q000209:etiology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires