title: Two new eicosanoids with a unique isovalerianic acid ester moiety from the South China Sea gorgonian Dichotella gemmacea.
abstract: Two new eicosanoids with a unique isovalerianic acid ester group at C-12, named dichotellates A (1) and B (2), were isolated from the gorgonian Dichotella gemmacea collected from the South China Sea using bioassay-guided fractionation. Their structures were established on the basis of extensive spectroscopic analysis including one-dimensional (1D) and two-dimensional (2D) NMR as well as high-resolution ESI-MS experiments. These two compounds were evaluated for their lethal activity toward brine shrimp Artemia salina and both showed weak activity.
authors.affiliation: Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, People's Republic of China. changyun@ouc.edu.cn
authors.forename: Chang-Yun
authors.initials: CY
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhao
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Liu
authors.forename: Chang-Lun
authors.initials: CL
authors.lastname: Shao
authors.forename: Qing-Ai
authors.initials: QA
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Gu
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry / Q000378:metabolism*; D002681:China; D015777:Eicosanoids / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy
chemical_list: D015777:Eicosanoids; D004952:Esters