title: Tei index (myocardial performance index) and cardiac biomarkers in dogs with parvoviral enteritis.
abstract: Tei index (myocardial performance) and cardiac biomarkers were evaluated in dogs with parvoviral enteritis (PVE). Tei index was calculated as isovolumic contraction time plus isovolumic relaxation time divided by ejection time. Myocardial and skeletal muscle damages were assessed by serum levels of cardiac troponin I (cTnI), creatine (phospho) kinase, lactate dehydrogenase and aspartate aminotransferase. Serum magnesium level was also determined. According to treatment response, dogs were divided into the survivor (n=20) and non-survivor groups (n=23). Seven healthy dogs served as controls. The mean value of the Tei index was higher in non-survivors, compared with survivors (p<0.02) and healthy controls (p<0.01). Serum level of cTnI in non-survivors was higher than that of survivors and controls (p<0.05). Tei index showed the highest sensitivity and specificity to predict mortality. The findings of an elevated Tei index and an increase in serum cTnI are factors associated with a poor prognosis in cases of canine parvovirosis.
authors.affiliation: Department of Internal Medicine, Uludag University, Bursa, Turkey.
authors.forename: Meric
authors.initials: M
authors.lastname: Kocaturk
authors.forename: Silvia
authors.initials: S
authors.lastname: Martinez
authors.forename: Oya
authors.initials: O
authors.lastname: Eralp
authors.forename: Asta
authors.initials: A
authors.lastname: Tvarijonaviciute
authors.forename: Jose
authors.initials: J
authors.lastname: Ceron
authors.forename: Zeki
authors.initials: Z
authors.lastname: Yilmaz
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000401:mortality; D004285:Dogs; D015150:Echocardiography, Doppler / Q000662:veterinary; D004751:Enteritis / Q000097:blood / Q000401:mortality / Q000662:veterinary / Q000821:virology; D005260:Female; D006334:Heart Function Tests / Q000662:veterinary*; D008297:Male; D009200:Myocardial Contraction; D010322:Parvoviridae Infections / Q000097:blood / Q000175:diagnosis / Q000401:mortality / Q000662:veterinary*; D017993:Parvovirus, Canine; D011379:Prognosis; D012372:ROC Curve; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000097:blood / Q000401:mortality / Q000662:veterinary / Q000821:virology
chemical_list: D015415:Biomarkers