title: Comparison of the Inverness Medical Acceava Strep A test with the Genzyme OSOM and Quidel QuickVue Strep A tests.
abstract: Previous studies of the accuracy of rapid in-office tests for group A Streptococcus had disparate results, ranging from a sensitivity of 70% to more than 90%. The sensitivity and specificity of 3 commercially available Strep A tests were determined in 2 private pediatric office settings. Acceava Strep A, Genzyme OSOM Strep A, and the Quidel QuickVue Strep A tests were the representative rapid tests for detection of Streptococcus pyogenes. Overnight culture on standard 5% sheep blood agar was the reference standard for this study. All 3 Clinical Laboratory Improvement Amendments-waived tests had sensitivities and specificities that exceeded 95%.
authors.affiliation: Inova Fairfax Hospital for Children, Falls Church, VA, USA.
authors.forename: Tanya
authors.initials: T
authors.lastname: Rogo
authors.forename: Richard H
authors.initials: RH
authors.lastname: Schwartz
authors.forename: David P
authors.initials: DP
authors.lastname: Ascher
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D001431:Bacteriological Techniques / Q000379:methods*; D002648:Child; D015169:Colony Count, Microbial / Q000379:methods*; D003470:Culture Media / Q000737:chemistry; D006801:Humans; D010612:Pharyngitis / Q000382:microbiology*; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000942:Antigens, Bacterial; D003470:Culture Media