title: Vasoplegia during cardiac surgery: current concepts and management.
abstract: Vasoplegic syndrome (VS) is a recognized and relatively common complication of cardiopulmonary bypass (CPB), appearing with an incidence ranging between 5% and 25%. It is characterized by significant hypotension, high or normal cardiac outputs and low systemic vascular resistance (SVR), and increased requirements for fluids and vasopressors during or after CPB. Patients developing VS are at increased risk for death and other major complications following cardiac surgery. This review will focus on the pathophysiology and contemporary strategies of treating VS encountered after CPB.
authors.affiliation: Department of Anesthesiology, Mount Sinai Medical Center, New York, New York 10029, USA. Gregory.fischer@mountsinai.org
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Fischer
authors.forename: Mathew A
authors.initials: MA
authors.lastname: Levin
mesh_terms: D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000401:mortality; D002315:Cardiopulmonary Bypass / Q000009:adverse effects* / Q000401:mortality; D005440:Fluid Therapy; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D012307:Risk Factors; D016896:Treatment Outcome; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D056987:Vasoplegia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*
chemical_list: D014662:Vasoconstrictor Agents