title: Miniplate osteosynthesis with four different systems in sheep.
abstract: The aim of this study was to compare a combination of a locking system with self-tapping (ST-L) or self-drilling-tapping (SDT-L) screws with a combination of conventional miniplates with self-tapping (ST) and self-forming (SF) screws. A standardized osteotomy and osteosynthesis with one of the above mentioned systems was performed in 24 sheep. Callus formation was measured with the help of CT scans assisted by a navigation system. Specimens of each osteotomy gap were taken and examined histologically. The best results were observed when self-tapping screws and the Mini-Locking-System (ST-L) were applied. The slowest healing was seen in animals treated with miniplates and SF screws. After 8 weeks an increase in bone formation could be observed in the ST, SF, SDT-L systems. The results after 8 weeks were comparable with those achieved by the ST-L system after 4 weeks. The improved stability of the osteosynthesis with the ST-L system resulted in early ossification of the osteotomy gap and the smallest amount of callus formation.
authors.affiliation: Department of Oral and Craniomaxillofacial Surgery, University Hospital Freiburg, Freiburg, Germany. ralf.gutwald@uniklinik-freiburg.de
authors.forename: R
authors.initials: R
authors.lastname: Gutwald
authors.forename: R
authors.initials: R
authors.lastname: Schön
authors.forename: M
authors.initials: M
authors.lastname: Metzger
authors.forename: K
authors.initials: K
authors.lastname: Kreutzer
authors.forename: B
authors.initials: B
authors.lastname: Rahn
authors.forename: R
authors.initials: R
authors.lastname: Schmelzeisen
authors.forename: S
authors.initials: S
authors.lastname: Sauerbier
mesh_terms: D000497:Alloys / Q000737:chemistry; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D001696:Biomechanical Phenomena; D001860:Bone Plates; D001863:Bone Screws; D002146:Bony Callus / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology; D004867:Equipment Design; D004868:Equipment Failure; D005452:Fluoresceins; D005456:Fluorescent Dyes; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010012:Osteogenesis / Q000502:physiology; D010027:Osteotomy / Q000295:instrumentation; D010636:Phenols; D012756:Sheep; D013454:Sulfoxides; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium / Q000737:chemistry; D014057:Tomography, X-Ray Computed; D019415:Torque; D014992:Xylenes
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D005452:Fluoresceins; D005456:Fluorescent Dyes; D010636:Phenols; D013454:Sulfoxides; D014992:Xylenes; C070282:Ti-6Al-7Nb alloy; D014025:Titanium; C016833:xylenol orange; C007740:fluorexon