title: Carbohydrate-based vaccines: challenges and opportunities.
abstract: Advances in the synthesis of oligo- or polysaccharides and new technologies developed in glycobiology studies have opened a new avenue in carbohydrate vaccine design. In principle, various types of cell-surface epitopes, characteristic of the invading organism or related to aberrant growth of cells, can be applied to develop vaccines. Numerous promising carbohydrate-based vaccine candidates have been prepared in recent years. This article, primarily for general readers, briefly presents the recent advances involving carbohydrate-based vaccines, including antibacterial, antiparasite, anticancer and antivirus vaccines.
authors.affiliation: Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan.
authors.forename: Yen-Lin
authors.initials: YL
authors.lastname: Huang
authors.forename: Chung-Yi
authors.initials: CY
authors.lastname: Wu
mesh_terms: D001428:Bacterial Vaccines / Q000737:chemistry / Q000276:immunology*; D019496:Cancer Vaccines / Q000737:chemistry / Q000276:immunology*; D002241:Carbohydrates / Q000276:immunology*; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D016052:Protozoan Vaccines / Q000737:chemistry / Q000276:immunology*; D014765:Viral Vaccines / Q000737:chemistry / Q000276:immunology*
chemical_list: D001428:Bacterial Vaccines; D019496:Cancer Vaccines; D002241:Carbohydrates; D000939:Epitopes; D016052:Protozoan Vaccines; D014765:Viral Vaccines