title: T-cryptantigen (TCA) activation in sever pneumonia complicated with multiple organ failure.
abstract: A 19-month-old boy presented RBC T-cryptantigen (TCA) activation with severe pneumonia complicated with abnormal coagulation. The boy received fresh frozen plasma before TCA activation was confirmed. He developed hemolysis and multiple organ failure. The hemolysis anemia was successfully treated with washed RBC transfusion. However, he had to use dialysis because of renal dysfunction. The case prompted an urgent call to screen RBC TCA-activation in selective pediatric patients.
authors.affiliation: Department of Blood Transfusion, Shengjing Hospital, China Medical University, Shenyang 110004, China. Electronic address: Wangqs18@126.com.
authors.forename: Qiushi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Blood Transfusion, Shengjing Hospital, China Medical University, Shenyang 110004, China.
authors.forename: Delong
authors.initials: D
authors.lastname: Liu
authors.affiliation: Department of Blood Transfusion, Shengjing Hospital, China Medical University, Shenyang 110004, China.
authors.forename: Yingzhe
authors.initials: Y
authors.lastname: Bai
mesh_terms: D000740:Anemia / Q000209:etiology; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000378:metabolism*; D017707:Erythrocyte Transfusion; D004912:Erythrocytes; D006461:Hemolysis; D006801:Humans; D007223:Infant; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology* / Q000628:therapy; D010951:Plasma Exchange; D011014:Pneumonia / Q000150:complications* / Q000628:therapy; D006435:Renal Dialysis
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; C016467:Thomsen-Friedenreich antigen