title: Cutaneous CD4+/CD56+ hematodermic neoplasm.
abstract: CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis. The characteristic features are expression of the T helper inducer cell marker CD4 and the NK-cell marker CD56 in the absence of other T cell or NKcell specific markers. Because of the rarity of this disease, we describe a 48 year old woman suffering from CD4+/CD56+ hematodermic neoplasm on her cheek without leukemic infiltration.
authors.affiliation: Department of Dermatology, Goztepe Training and Resach Hospital, Istanbul, Turkey. ilkin.dr@gmail.com
authors.forename: Ilkin
authors.initials: I
authors.lastname: Zindanci
authors.forename: Mukaddes
authors.initials: M
authors.lastname: Kavala
authors.forename: Nesimi
authors.initials: N
authors.lastname: Buyukbabani
authors.forename: Emek
authors.initials: E
authors.lastname: Kocaturk
authors.forename: Melek
authors.initials: M
authors.lastname: Koc
mesh_terms: D000328:Adult; D015704:CD4 Antigens / Q000096:biosynthesis*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology* / Q000473:pathology*; D019002:CD56 Antigen / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000276:immunology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000276:immunology
chemical_list: D015704:CD4 Antigens; D019002:CD56 Antigen