title: Assessment of aflatoxin exposure of laboratory worker during food contamination analyses. Assessment of the procedures adopted by an A.R.P.A.L. laboratory (Liguria Region Environmental Protection Agency).
abstract: BACKGROUND
  Aflatoxins are mycotoxins derived from foodstuffs colonized by fungal species of the genus Aspergillus; they are common food contaminants with immunosuppressive, mutagenic and carcinogenic activity. Aflatoxins are heat-resistant and are thus easily transmitted along the food chain. They are hepatotoxic and have the potential to induce hepatocellular carcinoma. Agri-food industry workers are thus at risk of ingestion as well as transmucosal absorption or inhalation of toxins released during product preparation or processing.
  
  
  OBJECTIVE
  To measure the levels of airborne mycotoxins, particularly aflatoxins, in a laboratory analysing imported foodstuffs for mycotoxin contamination.
  
  
  METHODS
  The protocol used to analyse a batch of shelled peanuts from Vietnam, especially the grinding phase, which is held to be at the highest risk ofgenerating airborne toxins, was assessed at the A.R.PA.L. laboratory (Liguria Region Environmental Protection Agency) of Genoa, Italy, which participates in a European aflatoxin monitoring project.
  
  
  RESULTS
  Wet grinding was performed to avoid production of large amounts of dust. Comparison of airborne concentrations before and after grinding with legal thresholds disclosed that the analytical procedures involved negligible aflatoxin levels for operators (environmental burden 0.11 pg/ m3).
  
  
  CONCLUSIONS
  Given the toxicity of aflatoxins, worker protection measures should be consistently adopted and enforced. Threshold limit values for working environments should be introduced besides the existing ones for public health.
authors.affiliation: Sezione di Medicina del Lavoro--DIMEL, Università degli studi di Genova. travers@unige.i
authors.forename: A
authors.initials: A
authors.lastname: Traverso
authors.forename: Viviana
authors.initials: V
authors.lastname: Bassoli
authors.forename: A
authors.initials: A
authors.lastname: Cioè
authors.forename: Silvia
authors.initials: S
authors.lastname: Anselmo
authors.forename: Marta
authors.initials: M
authors.lastname: Ferro
mesh_terms: D000348:Aflatoxins / Q000032:analysis*; D000395:Air Pollutants, Occupational / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D007558:Italy; D016273:Occupational Exposure / Q000032:analysis*; D011042:Poisons / Q000032:analysis*
chemical_list: D000348:Aflatoxins; D000395:Air Pollutants, Occupational; D011042:Poisons