title: A Biomechanical model of spiculated tumours under mammographic compressions.
abstract: The aim of this paper is to introduce effects well known to clinicians -but neglected to date- in the biomechanical modelling of breast malignant tumours. We develop a model of an isolated stellate breast tumour under mammographic compression forces. We study a range of reported mechanical properties, both linear elastic and hyperelastic. We also introduce different volumes of increased density/stiffness around the tumour. We show that each of these issues has a non-negligible effect on stresses and strains/deformations.
authors.affiliation: Department of Engineering Science, University of Oxford, Parks Road, OX1 3PJ, UK. cwessel@robots.ox.ac.uk
authors.forename: Carolina
authors.initials: C
authors.lastname: Wessel
authors.forename: Julia A
authors.initials: JA
authors.lastname: Schnabel
authors.forename: Michael
authors.initials: M
authors.lastname: Brady
mesh_terms: D016477:Artifacts; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D019245:Compressive Strength; D003198:Computer Simulation; D055119:Elastic Modulus; D005260:Female; D006801:Humans; D008954:Models, Biological; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity