title: [Sustained virological response in patients with coinfection by hepatitis C virus genotypes 1 and 2, after just nine weeks of antiviral therapy: case report].
abstract: A report of a 67 year-old male patient with positive serology for HCV. PCR revealed the presence of HCV RNA, viral load of 2,000 copies/mL and genotypes 1 and 2. The patient was treated with peginterferon alfa-2a at 180 mcg/week and ribavirin at 1,000 mg/day. In week four of treatment, HCV viral load was undetectable. In week nine, the patient developed hematemesis, worsening of asthenia, anorexia and impaired general condition, so the treatment was discontinued. The PCR was negative six months and one year after the cessation of treatment. The patient remains asymptomatic.
authors.affiliation: Fundação de Medicina Tropical do Amazonas, Manaus, AM.
authors.forename: Ana Ruth
authors.initials: AR
authors.lastname: Araújo
authors.forename: José Eduardo
authors.initials: JE
authors.lastname: Levi
authors.forename: Carlos Mauríco de
authors.initials: CM
authors.lastname: Almeida
authors.forename: Tatiane Amábili de
authors.initials: TA
authors.lastname: Lima
authors.forename: Laura Patrícia Viana
authors.initials: LP
authors.lastname: Maia
authors.forename: Kátia Luz
authors.initials: KL
authors.lastname: Torres
authors.forename: Andréa Monteiro
authors.initials: AM
authors.lastname: Tarragô
authors.forename: Flamir
authors.initials: F
authors.lastname: Victória
authors.forename: Marilu
authors.initials: M
authors.lastname: Victória
authors.forename: Sinésio
authors.initials: S
authors.lastname: Talhari
authors.forename: Adriana
authors.initials: A
authors.lastname: Malheiro
mesh_terms: D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D012367:RNA, Viral / Q000097:blood / Q000235:genetics; D011994:Recombinant Proteins; D012254:Ribavirin / Q000627:therapeutic use*; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D012367:RNA, Viral; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C100416:peginterferon alfa-2a