title: The problem of orphan drugs.
authors.forename: Robin E
authors.initials: RE
authors.lastname: Ferner
authors.forename: Dyfrig A
authors.initials: DA
authors.lastname: Hughes
mesh_terms: D017277:Drug Approval; D016527:Drug Costs; D005062:European Union; D006801:Humans; D007880:Legislation, Drug; D009965:Orphan Drug Production / Q000191:economics / Q000331:legislation & jurisprudence*