title: A shared egg donor program: which is the minimum number of oocytes to be allocated?
abstract: OBJECTIVE
  To evaluate which is the minimum number of oocytes to be allocated to each recipient in a shared egg donor program.
  
  
  METHODS
  We analyzed 953 recipients that received at least 4 metaphase II (MII) oocytes in the period 2006-2008. We retrospectively divided the recipients according to the number of MII oocytes actually received.
  
  
  RESULTS
  No statistically significant differences were found among the analyzed strata in clinical pregnancy rate (A:43.7%; B:45.6%; C:48.6%; D:45.5%; E:53%, P=NS) and miscarriage rate. However, the rate of top quality transferred embryos, and the embryo freezing rate were significantly higher among those recipients that received 7 or more mature eggs.
  
  
  CONCLUSIONS
  After a large sample was analyzed, no significant differences in fresh embryo transfer outcome were encountered when a different number of oocytes was allocated. A minimum of 4 MII oocytes seems to achieve satisfactory pregnancy rates in our shared egg donor program.
authors.affiliation: Center for Studies in Gynecology and Reproduction (CEGYR), Buenos Aires, Argentina. glujovsky@cegyr.com
authors.forename: Demian
authors.initials: D
authors.lastname: Glujovsky
authors.forename: Marcelo
authors.initials: M
authors.lastname: Dominguez
authors.forename: Gabriel
authors.initials: G
authors.lastname: Fiszbajn
authors.forename: Sergio
authors.initials: S
authors.lastname: Papier
authors.forename: Mariano
authors.initials: M
authors.lastname: Lavolpe
authors.forename: Carlos
authors.initials: C
authors.lastname: Sueldo
mesh_terms: D000328:Adult; D015925:Cryopreservation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008677:Metaphase; D008875:Middle Aged; D018587:Oocyte Donation / Q000379:methods*; D009865:Oocytes / Q000166:cytology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D016896:Treatment Outcome