title: Synthesis and antibacterial activity of copper-immobilized membrane comprising grafted poly(4-vinylpyridine) chains.
abstract: Poly(4-vinylpyridine) (P4VP) brushes were grafted onto microporous polysulfone (PSF) membranes via surface-initiated atom transfer radical polymerization (SI-ATRP) and then immobilized copper (II) ions on the modified membrane. Copper-loaded membranes exhibited excellent antibacterial properties with the added advantage of repeated use. The chemical composition and surface morphology of the functionalized membrane was characterized by ATR-FTIR, XPS, SEM, and AFM. The results showed that P4VP brushes clustered to rod-shaped covering and the sub-layer of membrane maintained sponge-like structures at the same time. Additionally, the kinetic study of SI-ATRP reaction revealed that the chain length of P4VP brushes increased linearly as the polymerization time increased. The antibacterial effects of copper-loaded CMPSF-g-P4VP membrane against Escherichiacoli were examined and the antibacterial efficiency reached 100% when 2.49wt.% of copper (II) ions was immobilized on membrane. The presented results could serve as a good starting point for the fabrication of antibacterial CMPSF membranes for waste-water treatment applications.
authors.affiliation: School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Qiu
authors.forename: Yan-Wu
authors.initials: YW
authors.lastname: Zhang
authors.forename: Ya-Tao
authors.initials: YT
authors.lastname: Zhang
authors.forename: Hao-Qin
authors.initials: HQ
authors.lastname: Zhang
authors.forename: Jin-Dun
authors.initials: JD
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D003300:Copper / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D015394:Molecular Structure; D011145:Polyvinyls / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial; D011145:Polyvinyls; C019535:poly(4-vinylpyridine); D003300:Copper