title: Stereospecific cross-coupling of secondary alkyl β-trifluoroboratoamides.
abstract: The stereospecific cross-coupling of enantioenriched nonbenzylic secondary alkyl boron compounds has been achieved. The high selectivity toward product formation over an undesired β-H elimination pathway is achieved via an intramolecular coordination of an ancillary carbonyl to the metal center in the diorganopalladium intermediate.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, USA.
authors.forename: Deidre L
authors.initials: DL
authors.lastname: Sandrock
authors.forename: Ludivine
authors.initials: L
authors.lastname: Jean-Gérard
authors.forename: Cheng-yi
authors.initials: CY
authors.lastname: Chen
authors.forename: Spencer D
authors.initials: SD
authors.lastname: Dreher
authors.forename: Gary A
authors.initials: GA
authors.lastname: Molander
mesh_terms: D000577:Amides / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000577:Amides; D001896:Boron Compounds