title: A highly selective fluorescent probe for visualization of organic hydroperoxides in living cells.
abstract: The transcriptional regulatory protein OhrR is converted into a fluorescent bioprobe capable of detecting organic hydroperoxides in living cells with high sensitivity and selectivity.
authors.affiliation: Department of Chemical Biology, College of Chemistry and Molecular Engineering, College of Engineering, Peking University, Beijing 100871, China.
authors.forename: Boxuan Simen
authors.initials: BS
authors.lastname: Zhao
authors.forename: Yujie
authors.initials: Y
authors.lastname: Liang
authors.forename: Yanqun
authors.initials: Y
authors.lastname: Song
authors.forename: Chunhong
authors.initials: C
authors.lastname: Zheng
authors.forename: Ziyang
authors.initials: Z
authors.lastname: Hao
authors.forename: Peng R
authors.initials: PR
authors.lastname: Chen
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002470:Cell Survival; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism*; D008958:Models, Molecular; D057054:Molecular Imaging / Q000379:methods*; D008969:Molecular Sequence Data; D009930:Organic Chemicals / Q000378:metabolism*; D015202:Protein Engineering; D017433:Protein Structure, Secondary; D013379:Substrate Specificity
chemical_list: D001426:Bacterial Proteins; D005456:Fluorescent Dyes; D009930:Organic Chemicals; D006861:Hydrogen Peroxide