title: Expanding application of the Boston type I keratoprosthesis due to advances in design and improved post-operative therapeutic strategies.
abstract: OBJECTIVE
  To evaluate how the advances in design of the Boston type I keratoprosthesis and in the treatment strategies to conquer the post operative complications have expanded the indications and application of this technology.
  
  
  METHODS
  A review and analysis of the keratoprosthesis literature specifically examining design modifications, treatment of post operative complications, and patient selection was performed.
  
  
  RESULTS
  Over the past two decades, many modifications to the design of the Boston type I keratoprosthesis and treatment of the patient in the post operative period have occurred. Also, the technology has been more widely accepted as a primary surgical option for patients with a poor preoperative prognosis for traditional penetrating keratoplasty. The outcomes of visual acuity, retention, and post-operative infection rates have all significantly improved since the technology has been modified and offers patients an alternative for visual rehabilitation.
  
  
  CONCLUSIONS
  Thanks to advances in design and perioperative care, the boston type i keratoprosthesis can now be considered a viable option for surgical visual rehabilitation in many patients with corneal pathology, and in certain groups the primary surgical procedure of choice.
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
authors.forename: Aisha S
authors.initials: AS
authors.lastname: Traish
authors.forename: James
authors.initials: J
authors.lastname: Chodosh
mesh_terms: D001187:Artificial Organs; D001672:Biocompatible Materials; D003315:Cornea; D003316:Corneal Diseases / Q000601:surgery*; D006801:Humans; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D019736:Prostheses and Implants; D011474:Prosthesis Design; D019919:Prosthesis Implantation
chemical_list: D001672:Biocompatible Materials; D019904:Polymethyl Methacrylate