title: Nonlinear analysis of movement-related changes in human subthalamic local field potentials.
abstract: Movement-related changes such as event-related desynchronizationcan (ERD) and event-related synchronization (ERS) can be found in human subthalamic nucleus (STN) with analysis on local field potentials (LFP) recorded from Parkinson's disease (PD) patients. Besides traditional time-frequency (TF) analysis, we introduced nonlinear analysis, bispectral and approximate entropy (ApEn), to measure the signal nonlinear correlation and regularity in neural activities. Movement-related changes were found in the beta band, bicoherence and ApEn, and variation during stationary movement is more available by nonlinear methods. Therefore, we suggest nonlinear analysis for further related studies.
authors.affiliation: Department of Electrical Engineering, National Chiao Tung University, Hsinchu, Taiwan.
authors.forename: Chun-Shu
authors.initials: CS
authors.lastname: Wei
authors.forename: Chon-Haw
authors.initials: CH
authors.lastname: Tsai
authors.forename: Shang-Ming
authors.initials: SM
authors.lastname: Chiou
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Hseu
authors.forename: Ta-Wei
authors.initials: TW
authors.lastname: Liu
authors.forename: Hsin-Yi
authors.initials: HY
authors.lastname: Lai
authors.forename: Ting-Fang
authors.initials: TF
authors.lastname: Chien
authors.forename: Yi-Hsuan
authors.initials: YH
authors.lastname: Kuo
authors.forename: Wan-Ting
authors.initials: WT
authors.lastname: Zhao
authors.forename: Yu-Shun
authors.initials: YS
authors.lastname: Tang
authors.forename: Sheng Yuan
authors.initials: SY
authors.lastname: Su
authors.forename: You-Yin
authors.initials: YY
authors.lastname: Chen
mesh_terms: D000368:Aged; D046690:Deep Brain Stimulation; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017711:Nonlinear Dynamics; D010300:Parkinson Disease / Q000503:physiopathology* / Q000628:therapy