title: Burden in caregivers of older adults with advanced illness.
abstract: OBJECTIVE
  To examine caregiver burden over time in caregivers of patients with advanced chronic disease.
  
  
  METHODS
  Observational cohort with interviews over 12 months.
  
  
  METHODS
  Community.
  
  
  METHODS
  Caregivers of 179 community-living persons aged 60 and older with advanced cancer, heart failure (HF), or chronic obstructive pulmonary disease (COPD).
  
  
  METHODS
  Caregiver burden was assessed using a short-form of the Zarit Burden Inventory to measure psychosocial distress.
  
  
  RESULTS
  At baseline, the median caregiver burden was 5 (interquartile range (IQR) 1-11), which indicates that the caregiver endorsed having at least two of 10 distressing concerns at least some of the time. Only 10% reported no burden. Although scores increased modestly over time, the association between time and burden was not significant in longitudinal multivariable analysis. High burden was associated with caregiver need for more help with daily tasks (odds ratio (OR)=23.13, 95% confidence interval (CI)=5.94-90.06) and desire for greater communication with the patient (OR=2.53, 95% CI=1.16-5.53). The longitudinal multivariable analysis did not yield evidence of associations between burden and patient sociodemographic or health characteristics.
  
  
  CONCLUSIONS
  Caregiver burden was common in caregivers of patients with cancer, HF, and COPD. High burden was associated with the caregiver's report of need for greater help with daily tasks but not with objective measures of the patient's need for assistance, such as symptoms or functional status, suggesting that burden may be a measure of the caregiver's ability to adapt to the caregiving role.
authors.affiliation: College of Medicine, Rush University, Chicago, Illinois, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Garlo
authors.forename: John R
authors.initials: JR
authors.lastname: O'Leary
authors.forename: Peter H
authors.initials: PH
authors.lastname: Van Ness
authors.forename: Terri R
authors.initials: TR
authors.lastname: Fried
mesh_terms: D000223:Adaptation, Psychological; D000368:Aged; D017028:Caregivers / Q000523:psychology*; D015331:Cohort Studies; D003144:Communication Barriers; D016001:Confidence Intervals; D003237:Connecticut / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology / Q000209:etiology; D005260:Female; D016330:Frail Elderly / Q000706:statistics & numerical data; D006333:Heart Failure / Q000451:nursing*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D020380:Needs Assessment; D009369:Neoplasms / Q000451:nursing*; D009483:Neuropsychological Tests; D016017:Odds Ratio; D029424:Pulmonary Disease, Chronic Obstructive / Q000451:nursing*; D012111:Residence Characteristics; D013315:Stress, Psychological / Q000209:etiology*; D011795:Surveys and Questionnaires; D013997:Time Factors