title: Stereoselective synthesis and structural correction of the naturally occurring lactone stagonolide G.
abstract: A convergent synthesis of the structure proposed for the naturally occurring lactone stagonolide G is described. All three stereocenters were created with the aid of asymmetric Brown allylations. The lactone ring was built by means of a ring-closing metathesis (RCM). The synthetic and the natural compound differed in their spectral properties. A new structure is now proposed for stagonolide G and demonstrated by means of a chemical transformation.
authors.affiliation: Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, Castellón, E-12080 Castellón, Spain.
authors.forename: César A
authors.initials: CA
authors.lastname: Angulo-Pachón
authors.forename: Santiago
authors.initials: S
authors.lastname: Díaz-Oltra
authors.forename: Juan
authors.initials: J
authors.lastname: Murga
authors.forename: Miguel
authors.initials: M
authors.lastname: Carda
authors.forename: J Alberto
authors.initials: JA
authors.lastname: Marco
mesh_terms: D002384:Catalysis; D006573:Heterocyclic Compounds, 1-Ring / Q000138:chemical synthesis*; D007783:Lactones / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D006573:Heterocyclic Compounds, 1-Ring; D007783:Lactones; C527511:stagonolide