title: [Prognostic analysis of partial atrium or large blood vessel resection for treatment of locally advanced lung cancer].
abstract: OBJECTIVE
  To explore the value of partial atrium or large blood vessel resection for the treatment of locally advanced lung cancer.
  
  
  METHODS
  Thirty-five patients with locally advanced lung cancer (T(4)N(0)-N(2)M(0)) underwent lobectomy or pneumonectomy combined with intrapericardial vascular management or partial resection of the atrium. Of the 35 patients , 15 underwent left pneumonectomy combined with partial resection of the left atrium, 3 had pneumonectomy and partial resection of pulmonary artery trunk, 11 received right pneumonectomy and partial resection of the left atrium, 3 had middle and lower lobectomies and partial resection of the left atrium, and 3 underwent right upper lobectomy, partial resection of the superior vena cava and replacement of artificial blood vessel.
  
  
  RESULTS
  No death occurred in the 35 patients. Postoperative arrhythmia occurred in 4 cases and respiratory failure in 2 cases. The 1, 2, 3 and 4 year survival rates of the patients were 79.2% (19/24), 53.3% (8/15), 46.2% (6/13) and 36.4% (4/11), respectively. Pathologically, 27 patients had squamous carcinoma, 3 had adenocarcinoma, 3 had adenosquamous carcinoma and 2 had large cell carcinoma. In TNM staging, 6 were in T(4)N(0)M(0), 11 in T(4)N(1)M(0) and 18 in T(4)N(2)M(0).
  
  
  CONCLUSIONS
  Pneumonectomy or lobectomy combined with intrapericardial vascular management or partial resection of the atrium can enhance the possibility of radical resection of locally advanced lung cancer and increase the long term survival rate.
authors.affiliation: Department of Thoracic Surgery, General Hospital of PLA, Beijing 100853, China. zhangbaoshi407@163.com
authors.forename: Bao-shi
authors.initials: BS
authors.lastname: Zhang
authors.forename: Chang-hai
authors.initials: CH
authors.lastname: Yu
authors.forename: Yi-ming
authors.initials: YM
authors.lastname: Zhang
authors.forename: Jian-qi
authors.initials: JQ
authors.lastname: Yu
authors.forename: Nai-kang
authors.initials: NK
authors.lastname: Zhou
mesh_terms: D000368:Aged; D005260:Female; D006325:Heart Atria / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D014683:Vena Cava, Superior / Q000601:surgery*