title: The RIKEN integrated database of mammals.
abstract: The RIKEN integrated database of mammals (http://scinets.org/db/mammal) is the official undertaking to integrate its mammalian databases produced from multiple large-scale programs that have been promoted by the institute. The database integrates not only RIKEN's original databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
authors.affiliation: RIKEN BioResource Center, Tsukuba, Japan. toyoda@base.riken.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Masuya
authors.forename: Yuko
authors.initials: Y
authors.lastname: Makita
authors.forename: Norio
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Koro
authors.initials: K
authors.lastname: Nishikata
authors.forename: Yuko
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: Koji
authors.initials: K
authors.lastname: Doi
authors.forename: Terue
authors.initials: T
authors.lastname: Takatsuki
authors.forename: Kazunori
authors.initials: K
authors.lastname: Waki
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Tanaka
authors.forename: Manabu
authors.initials: M
authors.lastname: Ishii
authors.forename: Akihiro
authors.initials: A
authors.lastname: Matsushima
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hijikata
authors.forename: Kouji
authors.initials: K
authors.lastname: Kozaki
authors.forename: Teiichi
authors.initials: T
authors.lastname: Furuichi
authors.forename: Hideya
authors.initials: H
authors.lastname: Kawaji
authors.forename: Shigeharu
authors.initials: S
authors.lastname: Wakana
authors.forename: Yukio
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yoshiki
authors.forename: Takehide
authors.initials: T
authors.lastname: Murata
authors.forename: Kaoru
authors.initials: K
authors.lastname: Fukami-Kobayashi
authors.forename: Sujatha
authors.initials: S
authors.lastname: Mohan
authors.forename: Osamu
authors.initials: O
authors.lastname: Ohara
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Hayashizaki
authors.forename: Riichiro
authors.initials: R
authors.lastname: Mizoguchi
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Obata
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Toyoda
mesh_terms: D000818:Animals; D016208:Databases, Factual; D030541:Databases, Genetic; D006801:Humans; D020407:Internet; D008322:Mammals / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D018511:Systems Integration; D014584:User-Computer Interface