title: Multi-organ dysfunction in bodybuilding possibly caused by prolonged hypercalcemia due to multi-substance abuse: case report and review of literature.
abstract: A 26-year-old male bodybuilder was admitted to the surgical department of a Danish community hospital for hematemesis. During the clinical interview, he revealed that he had recently finished a course of anabolic steroids and erythropoietin. The patient also had a previous history of infections and chronic ulcers due to paraffin-oil injections in both upper arms one year before. Over the course of the next few hours, the patient developed signs of multi-organ dysfunction, including pancreatitis, hemorrhagic gastritis, nephropathy with temporary anuria, and respiratory insufficiency, and was transferred to the ICU. After manometric monitoring on the patient's upper arms proved difficult, invasive blood pressure monitoring was used and revealed that the patient was in a state of hypertensive crisis. This case of multi-organ dysfunction was possibly caused by multi-substance-induced hypercalcemia.
authors.affiliation: Hospital Zealand South/Nykøbing F Hospital, Department of Anesthesiology, Nykøbing F, Denmark. schaefer@dadlnet.dk
authors.forename: C N
authors.initials: CN
authors.lastname: Schäfer
authors.forename: H
authors.initials: H
authors.lastname: Guldager
authors.forename: H L
authors.initials: HL
authors.lastname: Jørgensen
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000009:adverse effects; D003422:Critical Care; D003718:Denmark; D004921:Erythropoietin / Q000009:adverse effects; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000150:complications*; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology*; D019966:Substance-Related Disorders / Q000150:complications*; D014891:Weight Lifting
chemical_list: D045930:Anabolic Agents; D004921:Erythropoietin