title: Discovering neuroprotection in Parkinson's disease, or getting to haphazard.
abstract: Despite significant research efforts, a therapy to slow or halt the progression of Parkinson's disease ("neuroprotection") remains elusive. The discovery of such a therapy will likely require important observations from a number of perspectives: basic science investigation, clinical research, and careful observation in medical practice. Any possible insights will require confirmation in rigorous clinical trial testing. Combining the useful insights from all perspectives may be the most promising approach to discovering a neuroprotective therapy.
authors.affiliation: University of Rochester Medical Center, Rochester, NY, USA. karl.kieburtz@ctcc.rochester.edu
authors.forename: Karl
authors.initials: K
authors.lastname: Kieburtz
mesh_terms: D018450:Disease Progression; D015195:Drug Design; D019317:Evidence-Based Medicine; D006801:Humans; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy* / Q000473:pathology / Q000517:prevention & control; D057170:Translational Research, Biomedical
chemical_list: D018696:Neuroprotective Agents