title: [Panic after LASIK: acute medication-induced myopic recurrence after refractive surgery].
abstract: We report a case of acute myopic recurrence in a 38-year-old patient in a state of panic with a condition corresponding to LASIK 4 months earlier. The patient had commenced topiramate treatment 1 week previously, which is an antiepileptic drug also approved for migraine treatment. The symptoms were due to a rare topiramate-induced side effect (SE) with ciliochoroidal effusion, anterior shift of the lens-iris diaphragm and induced myopia. Cessation of topiramate led to complete remission of this idiosyncratic reaction, however, the patient's anxiety was impressive. Ocular administration of Topiramat-SE should thus be clarified.
authors.affiliation: Zentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Strasse 62, 50924 Köln, Deutschland. philmuether@mac.com
authors.forename: P S
authors.initials: PS
authors.lastname: Muether
authors.forename: G
authors.initials: G
authors.lastname: Welsandt
authors.forename: T S
authors.initials: TS
authors.lastname: Dietlein
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D009216:Myopia / Q000150:complications* / Q000601:surgery*; D016584:Panic Disorder / Q000209:etiology* / Q000517:prevention & control*; D012008:Recurrence; D000077236:Topiramate; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose