title: [The influence of remifentanil on intra- and postoperative drug cost].
abstract: BACKGROUND
  Intraoperative use of remifentanil requires much more analgesics postoperatively. Moreover, remifentanil causes intraoperative hypotension and bradycardia.
  
  
  METHODS
  The objectives are to compare intra- and post-operative drug cost between patients who received remifentanil (Group R, n = 72) and those who received fentanyl (Group F, n = 66) during laparoscopic cholecystectomy retrospectively.
  
  
  RESULTS
  The baseline demographics were similar between the two groups. Intraoperative drug costs were 7,782 +/- 1,579 yen in Group R and 6,235 +/- 1,037 yen in Group E Postoperative drug costs were 364 +/- 521 yen in Group R and 146 +/- 153 yen in Group E Total drug costs were 8,167 +/- 1,607 yen in Group R and 6,381 +/- 1,042 yen in Group E These reached statistical significance (P < 0.01). Length of hospital stay (days) between the two groups were comparable.
  
  
  CONCLUSIONS
  Remifentanil anesthesia requires much more intra- and post-operative drug cost than fentanyl anesthesia for laparoscopic cholecystectomy.
authors.affiliation: Department of Anesthesia, Toyama Prefectural Central Hospital, Toyama 930-8550.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kamitani
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yoshida
authors.forename: Harumi
authors.initials: H
authors.lastname: Miyoshi
authors.forename: Mariko
authors.initials: M
authors.lastname: Takebe
authors.forename: Hisakatsu
authors.initials: H
authors.lastname: Ito
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Komiya
authors.forename: Riho
authors.initials: R
authors.lastname: Arai
authors.forename: Miki
authors.initials: M
authors.lastname: Sato
authors.forename: Kousou
authors.initials: K
authors.lastname: Matsuura
mesh_terms: D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D016527:Drug Costs; D005260:Female; D005283:Fentanyl / Q000494:pharmacology; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000494:pharmacology*; D011184:Postoperative Period; D000077208:Remifentanil
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D005283:Fentanyl