title: Pulse wave velocity in patients with severe head injury a pilot study.
abstract: The study aimed to determine the potential of pulse wave velocity measurements to reflect changes in compliant cerebral arteries/arterioles in head injured patients. The approach utilizes the electrocardiogram and intracranial pressure signals to measure the wave transit time between heart and cranial cavity. Thirty five clinical records of nineteen head injured patients, with different levels of cerebrovascular pressure-reactivity response, were investigated through the study. Results were compared with magnitude of normalized transfer function at the fundamental cardiac frequency. In patients with intact cerebrovascular pressure-reactivity, magnitude of normalized transfer function at the fundamental cardiac component was found to be highly correlated with pulse wave transit time.
authors.affiliation: Department of Signals and Systems, Signal Processing, Chalmers University of Technology, Sweden. shahsava@chalmers.se
authors.forename: S
authors.initials: S
authors.lastname: Shahsavari
authors.forename: T
authors.initials: T
authors.lastname: McKelvey
authors.forename: B
authors.initials: B
authors.lastname: Rydenhag
authors.forename: C Eriksson
authors.initials: CE
authors.lastname: Ritzén
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D058256:Brain Waves; D006259:Craniocerebral Trauma / Q000503:physiopathology*; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology; D010865:Pilot Projects; D011674:Pulse; D015203:Reproducibility of Results; D013997:Time Factors