title: P1,P2-diimidazolyl derivatives of pyrophosphate and bis-phosphonates--synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs.
abstract: P(1),P(2)-Diimidazolyl derivatives of pyrophosphate and halomethylene-bis-phosphonates have been synthesized and characterized, and the mechanism of their formation was studied. These reagents enable synthesis of dinucleoside tetraphosphates and tetraphosphonates conveniently and in high yields.
authors.affiliation: GLSynthesis Inc., One Innovation Dr, Worcester, MA 01605, USA. ivan.yanachkov@glsynthesis.com
authors.forename: Ivan B
authors.initials: IB
authors.lastname: Yanachkov
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Dix
authors.forename: Milka I
authors.initials: MI
authors.lastname: Yanachkova
authors.forename: George E
authors.initials: GE
authors.lastname: Wright
mesh_terms: D003500:Cyclization; D015226:Dinucleoside Phosphates / Q000138:chemical synthesis*; D011756:Diphosphates / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry*
chemical_list: D015226:Dinucleoside Phosphates; D011756:Diphosphates; D007093:Imidazoles; D063065:Organophosphonates; C029899:imidazole