title: Buprenorphine in postoperative pain management.
abstract: Several decades ago, the analgesic properties of buprenorphine were discovered. Its approval for the use as an agent for the treatment of opioid abuse has led to increasing numbers of patients presenting for surgery on buprenorphine. This article describes the challenges, advantages, and disadvantages of the use of buprenorphine as an analgesic for postoperative pain in patients with and without preoperative maintenance therapy.
authors.affiliation: Department of Anesthesiology, Yale University, 333 Cedar Street, New Haven, CT 06520, USA. nalinivg@gmail.com
authors.forename: Nalini
authors.initials: N
authors.lastname: Vadivelu
authors.forename: Muhammad
authors.initials: M
authors.lastname: Anwar
mesh_terms: D000208:Acute Disease; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D002047:Buprenorphine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D002908:Chronic Disease; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy*; D011957:Receptors, Opioid / Q000378:metabolism
chemical_list: D000701:Analgesics, Opioid; D011957:Receptors, Opioid; D002047:Buprenorphine