title: Iron-catalyzed synthesis of polysubstituted pyrroles via [4C+1N] cyclization of 4-acetylenic ketones with primary amines.
abstract: A highly efficient iron-catalyzed approach to polysubstituted pyrroles has been developed through the [4C+1N] cyclization of 4-acetylenic ketones with primary amines, leading to the synthesis of a variety of tetra- and fully-substituted pyrroles as well as fused pyrrole derivatives in good to excellent yields.
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China.
authors.forename: Yeming
authors.initials: Y
authors.lastname: Wang
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi
authors.forename: Dehua
authors.initials: D
authors.lastname: Li
authors.forename: Peiqiu
authors.initials: P
authors.lastname: Liao
authors.forename: Yidong
authors.initials: Y
authors.lastname: Wang
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007501:Iron / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D000588:Amines; D007659:Ketones; D011758:Pyrroles; D007501:Iron