title: Edge-based partial volume averaging estimation for FLAIR MRI with white matter lesions.
abstract: Through the combination of intensity and fuzzy edge strength measures, a new partial volume averaging (PVA) quantification technique for FLAIR MRI with white matter lesions (WML) is developed. It is focused on an edge-based approach, which "probes" for PVA voxels via a global estimate for the change in the proportion of tissues α'. This estimate is refined according to a probabilistic threshold, and the result is decoded to find the proportion of tissues fraction α - the percentage of one tissue found in a mixture voxel. The results from several images are shown illustrating how the technique may be used to segment PVA and pure tissue classes. The result is a non-model based approach to the detection and quantification of PVA.
authors.affiliation: Elec. and Comp. Eng. Dept., University of Toronto, Canada. akhademi@ieee.org
authors.forename: April
authors.initials: A
authors.lastname: Khademi
authors.forename: Anastasios
authors.initials: A
authors.lastname: Venetsanopoulos
authors.forename: Alan R
authors.initials: AR
authors.lastname: Moody
mesh_terms: D016477:Artifacts; D001921:Brain / Q000473:pathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*