title: Profile of glomerular diseases in a public hospital of Federal District, Brazil.
abstract: BACKGROUND
  Glomerular diseases are a frequent etiology of chronic kidney disease, especially in the developing countries.
  
  
  OBJECTIVE
  To determine the profile of such glomerulopathies in a public hospital located in the city of Brasilia, Federal District.
  
  
  METHODS
  121 renal biopsies in different patients were performed by the Renal Division of Hospital Regional da Asa Norte (HRAN) between August 2005 and May 2009. Eight renal biopsies in renal-transplant patients were excluded and the medical records of 113 remaining patients were analyzed. Analyzed data: sex, age, laboratory exams, glomerular syndrome, clinical diagnosis, degree of interstitial fibrosis, immunosuppressants use, need for dialysis and clinical outcome.
  
  
  RESULTS
  The age average was 34.9 ± 16.2 years-old, a predominance of male patients (51.3%). Major glomerular syndromes were: nephrotic syndrome (41.6%) and the rapidly- progressive glomerulonephritis (35.4%). Among primary glomerulopathies focal glomerulosclerosis (26.8%) followed by IgA nephropathy (25%) were predominant; and among the most prevalent secondary glomerulopathies we had lupus nephritis (50%) and diffuse exudative proliferative glomerulonephritis (34.2%).The majority of the patients used immunosuppressants (68.1%) and almost one third of them (29.2%) needed dialysis during their hospitalization. Progressed to chronic dialysis therapy 13.3% of the patients and 10.6% died.
  
  
  CONCLUSIONS
  This study may contribute to better epidemiological understanding of glomerular diseases in the Federal District, guiding the adoption of public policies aiming the quick clinical treatment of such diseases.
authors.affiliation: Hospital Regional da Asa Norte, Brasília, DF, Bazil. fabionefro@gmail.com
authors.forename: Fabio Humberto Ribeiro Paes
authors.initials: FH
authors.lastname: Ferraz
authors.forename: Carla Guapindaia Braga
authors.initials: CG
authors.lastname: Martins
authors.forename: Janaína Costa
authors.initials: JC
authors.lastname: Cavalcanti
authors.forename: Frederico Lopes de
authors.initials: FL
authors.lastname: Oliveira
authors.forename: Renata Miguel
authors.initials: RM
authors.lastname: Quirino
authors.forename: Rosana
authors.initials: R
authors.lastname: Chicon
authors.forename: Sergio Raimundini
authors.initials: SR
authors.lastname: Cavechia
mesh_terms: D000328:Adult; D001706:Biopsy; D001938:Brazil; D005260:Female; D006779:Hospitals, Public; D006801:Humans; D007674:Kidney Diseases / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies