title: Women's perspective of botulinum toxin treatment for overactive bladder symptoms.
abstract: OBJECTIVE
  This study aimed to evaluate the women's' views and expectations about outcomes and complications of botulinum toxin treatment for overactive bladder (OAB) symptoms.
  
  
  METHODS
  Consecutive women with OAB symptoms and detrusor overactivity were requested to fill out a multiple choice questionnaire to assess whether they would consider botulinum and what outcomes as well as complications they would find acceptable to undergo this treatment.
  
  
  RESULTS
  Two hundred sixty-one women, mean age of 58 (range, 38-78) years, were studied. Two hundred twenty-four were treatment-naive women (group A), while 37 were no responders to anticholinergics (group B). Only 49.6% of women in group A and 54% in group B would accept botulinum toxin. No significant differences were found between treatment-naive women and non-responders to anticholinergics (p > 0.05).
  
  
  CONCLUSIONS
  Acceptance of botulinum toxin treatment involves a complex interaction of efficacy and possible complications. The balance of these factors changes the acceptability of the treatment.
authors.affiliation: Urogynaecology Department, Imperial College School of Medicine, St. Mary's Hospital, Cambridge Wing, Praed Street, London W2 1NY, UK. a.digesu@imperial.ac.uk
authors.forename: G Alessandro
authors.initials: GA
authors.lastname: Digesu
authors.forename: Demetri
authors.initials: D
authors.lastname: Panayi
authors.forename: Caroline
authors.initials: C
authors.lastname: Hendricken
authors.forename: Michelle
authors.initials: M
authors.lastname: Camarata
authors.forename: Ruwan
authors.initials: R
authors.lastname: Fernando
authors.forename: Vikram
authors.initials: V
authors.lastname: Khullar
mesh_terms: D000328:Adult; D000368:Aged; D018726:Anti-Dyskinesia Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001905:Botulinum Toxins / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000523:psychology* / Q000706:statistics & numerical data; D011446:Prospective Studies; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins