title: Biocompatible functionalisation of starch.
abstract: The enzyme catalysed esterification of starch and fatty acids with terminal triple bonds is described. This material can be used as an acceptor for azide containing molecules, through azide/alkyne cycloaddition. The potential is illustrated by the production of fluorescently-labelled starch, and a biotinylated derivative which can bind streptavidin.
authors.affiliation: WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow, G1 1XL, UK.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Alissandratos
authors.forename: Nina
authors.initials: N
authors.lastname: Baudendistel
authors.forename: Bernhard
authors.initials: B
authors.lastname: Hauer
authors.forename: Kai
authors.initials: K
authors.lastname: Baldenius
authors.forename: Sabine
authors.initials: S
authors.lastname: Flitsch
authors.forename: Peter
authors.initials: P
authors.lastname: Halling
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D004951:Esterification; D005231:Fatty Acids, Unsaturated / Q000737:chemistry; D013213:Starch / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D001672:Biocompatible Materials; D005231:Fatty Acids, Unsaturated; C048289:10-undecynoic acid; D003300:Copper; D013213:Starch