title: Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals Lactobacillus iners as the predominant Lactobacillus Species.
abstract: The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV(+) women and 90% of HIV(-) women. This has implications for resistance of HIV(+) and HIV(-) women to genital colonization by pathogenic organisms.
authors.affiliation: Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA. gspear@rush.edu
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Spear
authors.forename: Douglas
authors.initials: D
authors.lastname: Gilbert
authors.forename: Alan L
authors.initials: AL
authors.lastname: Landay
authors.forename: Reza
authors.initials: R
authors.lastname: Zariffard
authors.forename: Audrey L
authors.initials: AL
authors.lastname: French
authors.forename: Pranjal
authors.initials: P
authors.lastname: Patel
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Gillevet
mesh_terms: D044822:Biodiversity; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D015658:HIV Infections; D006801:Humans; D007778:Lactobacillus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D054892:Metagenome; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D014621:Vagina / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S