title: Automatic segmentation of the spinal cord and the dural sac in lumbar MR images using gradient vector flow field.
abstract: A Computer-aided diagnosis (CAD) system aims to facilitate characterization and quantification of abnormalities as well as minimize interpretation errors caused by tedious tasks of image screening and radiologic diagnosis. The system usually consists of segmentation, feature extraction and diagnosis, and segmentation significantly affects the diagnostic performance. In this paper, we propose an automatic segmentation method that extracts the spinal cord and the dural sac from T2-weighted sagittal magnetic resonance (MR) images of lumbar spine without the need of any human intervention. Our method utilizes a gradient vector flow (GVF) field to find the candidate blobs and performs a connected component analysis for the final segmentation. MR Images from fifty two subjects were employed for our experiments and the segmentation results were quantitatively compared against reference segmentation by two medical specialists in terms of a mutual overlap metric. The experimental results showed that, on average, our method achieved a similarity index of 0.7 with a standard deviation of 0.0571 that indicated a substantial agreement. We plan to apply this segmentation method to computer-aided diagnosis of many lumbar-related pathologies.
authors.affiliation: Department of Computer Science and Engineering, University at Buffalo (SUNY), Buffalo, NY 14260, USA. jkoh@@buffalo.edu
authors.forename: Jaehan
authors.initials: J
authors.lastname: Koh
authors.forename: Taehyong
authors.initials: T
authors.lastname: Kim
authors.forename: Vipin
authors.initials: V
authors.lastname: Chaudhary
authors.forename: Gurmeet
authors.initials: G
authors.lastname: Dhillon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001185:Artificial Intelligence; D004388:Dura Mater / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008159:Lumbar Vertebrae / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013116:Spinal Cord / Q000033:anatomy & histology*