title: Computed tomographic angiography and venography for young or nonhypertensive patients with acute spontaneous intracerebral hemorrhage.
abstract: OBJECTIVE
  we compared the effectiveness of using computed tomographic angiography and venography (CTAV) with digital subtraction angiography (DSA) in young or nonhypertensive patients with acute spontaneous intracerebral hemorrhage.
  
  
  METHODS
  we prospectively recruited 109 young (age between 18 and 45 years) or nonhypertensive patients with acute spontaneous intracerebral hemorrhage for this comparative study. All patients had CTAV using multidetector CT with 64 detectors. They were then scheduled to have catheter angiography the next day. Radiological data were collected for blinded analysis.
  
  
  RESULTS
  DSA-positive pathologies causing hemorrhage were identified in 37 (33%) patients, which included cerebral arteriovenous malformation in 22 cases. The positive and negative predictive values of CTAV for DSA-positive pathologies causing hemorrhage were 97.3% (95% CI, 88.3%-99.9%) and 100% (95% CI, 95.9%-100%), respectively.
  
  
  CONCLUSIONS
  CTAV was able to detect DSA-positive pathologies causing acute spontaneous intracerebral hemorrhage in young (age between 18 and 45 years) or nonhypertensive patients with high positive and negative predictive values.
authors.affiliation: Division of Neurosurgery, Department of Imaging, Prince of Wales Hospital, The Chinese Univeristy of Hong Kong, Hong Kong, China. georgewong@surgery.cuhk.edu.hk
authors.forename: George Kwok Chu
authors.initials: GK
authors.lastname: Wong
authors.forename: Deyond Yung Woon
authors.initials: DY
authors.lastname: Siu
authors.forename: Jill Morales
authors.initials: JM
authors.lastname: Abrigo
authors.forename: Wai Sang
authors.initials: WS
authors.lastname: Poon
authors.forename: Federick Chun Pong
authors.initials: FC
authors.lastname: Tsang
authors.forename: Xian Lun
authors.initials: XL
authors.lastname: Zhu
authors.forename: Simon Chun Ho
authors.initials: SC
authors.lastname: Yu
authors.forename: Anil Tejbhan
authors.initials: AT
authors.lastname: Ahuja
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed