title: [Incidental carcinoma in thyroid pathology: our experience and review of the literature].
abstract: The diagnosis of incidental thyroid carcinoma in patients submitted to thyroidectomy for a benign disease is quite frequent. A retrospective analysis was performed on 240 patients submitted to surgical intervention in order to establish the incidence of the carcinoma. One hundred sixty five patients (68.75%) were affected by benign disease (132 multinodular goiter, 30 uninodular goiter, 2 Plummer and 1 Basedow) and 75 (31.25%) by carcinoma. In 30 of 165 patients (18.2 %), affected by benign disease, occurred a histological diagnosis of thyroid carcinoma, (18 papillary carcinoma, 6 follicular carcinoma, 5 papillary carcinoma follicular variant and 1 oncocytic carcinoma). In this study it's considered incidental thyroid carcinoma the one occurred in patients who never underwent FNA and there were no suspicious features in all exams that may suggest the presence of carcinoma. Fifteen of the 30 incidental carcinoma (50%) were microcarcinomas; in the other 13, dimensions were more than 1 cm, but less than 2 cm in 9 cases. Two patients had a synchronous carcinoma. Actually these patients are still in a follow up program and no recurrency of disease is occasionally observed. This study shows that the only way to put doubts on the real benignity of the disease is the fine needle aspiration; there are no other instruments that could let think about the occurrence of the carcinoma. Moreover in the majority of cases the incidental carcinoma is a microcarcinoma, it doesn't reach significant volume, may be not centered by a FNAB, but in must cases it's not really biologically aggressive.
authors.affiliation: Dipartimento dell'Emergenza e dei Trapianti di Organi, Università degli Studi di Bari, Bari.
authors.forename: Angela
authors.initials: A
authors.lastname: Pezzolla
authors.forename: Serafina
authors.initials: S
authors.lastname: Lattarulo
authors.forename: Marialessia
authors.initials: M
authors.lastname: Milella
authors.forename: Graziana
authors.initials: G
authors.lastname: Barile
authors.forename: Bianca
authors.initials: B
authors.lastname: Pascazio
authors.forename: Anna
authors.initials: A
authors.lastname: Ciampolillo
authors.forename: Gennaro
authors.initials: G
authors.lastname: Fabiano
authors.forename: Nicola
authors.initials: N
authors.lastname: Palasciano
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D018249:Adenoma, Oxyphilic / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006044:Goiter, Nodular / Q000473:pathology; D006111:Graves Disease / Q000473:pathology; D006801:Humans; D015994:Incidence; D033162:Incidental Findings; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011004:Plummer-Vinson Syndrome / Q000473:pathology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery