title: 3-D flow characterization and shear stress in a stenosed carotid artery bifurcation model using stereoscopic PIV technique.
abstract: The carotid artery bifurcation is a common site of atherosclerosis which is a major leading cause of ischemic stroke. The impact of stenosis in the atherosclerotic carotid artery is to disturb the flow pattern and produce regions with high shear rate, turbulence, and recirculation, which are key hemodynamic factors associated with plaque rupture, clot formation, and embolism. In order to characterize the disturbed flow in the stenosed carotid artery, stereoscopic PIV measurements were performed in a transparent model with 50% stenosis under pulsatile flow conditions. Simulated ECG gating of the flowrate waveform provides external triggering required for volumetric reconstruction of the complex flow patterns. Based on the three-component velocity data in the lumen region, volumetric shear-stress patterns were derived.
authors.affiliation: Department of Physics and Astronomy, the University of Western Ontario, London, N6A 3K7 Canada. skefayat@uwo.ca
authors.forename: Sarah
authors.initials: S
authors.lastname: Kefayati
authors.forename: Tamie L
authors.initials: TL
authors.lastname: Poepping
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002339:Carotid Arteries / Q000473:pathology / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000473:pathology* / Q000503:physiopathology*; D003198:Computer Simulation; D006801:Humans; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D012212:Rheology / Q000379:methods*; D033081:Shear Strength