title: [Fournier's disease. Clinical case].
abstract: Fournier's disease is a necrotizing fasciitis that prefers the male and which is located in the perineal area. In view of possible complications related to sepsis, systemic organ impairment and high mortality, is now considered a urological emergency. The main causes are infections of urethral and anorectal tract, immunodepression syndromes, diabetes mellitus and trauma. Infections are mixed with aerobic and anaerobic germs responsible of necrosis of tissue disorders due to the phenomena of necrotizing immunovasculitis disease. We present a case of Fournier's disease in perineal area, with gangrenosum necrotic evolution treated with antibiotic therapy, curettage of the necrotic tissue and local disinfection with saline and antiseptics solution. A total parenteral nutrition to ensure maximum perineal decontamination has been made. The extensive loss of substance scrotal was rebuilt in 25- day while the anal wound has healed spontaneously after complete surgical curettage.
authors.forename: M
authors.initials: M
authors.lastname: Pedalino
authors.forename: O G
authors.initials: OG
authors.lastname: Di Primio
authors.forename: R
authors.initials: R
authors.lastname: Vella
authors.forename: E
authors.initials: E
authors.lastname: Vercesi
authors.forename: G
authors.initials: G
authors.lastname: Marino
mesh_terms: D000368:Aged; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D003646:Debridement; D001728:Dicumarol / Q000009:adverse effects / Q000627:therapeutic use; D004198:Disease Susceptibility; D004630:Emergencies; D005334:Fever / Q000209:etiology; D018934:Fournier Gangrene / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D006484:Hemorrhoids / Q000150:complications; D006801:Humans; D006940:Hyperemia / Q000209:etiology; D006943:Hyperglycemia / Q000150:complications; D015378:Imipenem / Q000627:therapeutic use; D007964:Leukocytosis / Q000209:etiology; D008297:Male; D010289:Parenteral Nutrition, Total; D010502:Perineum; D012611:Scrotum / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D015378:Imipenem; D001728:Dicumarol; D000583:Amikacin