title: A case of phospholipase A₂ receptor-positive membranous nephropathy preceding sarcoid-associated granulomatous tubulointerstitial nephritis.
abstract: We report the case of a 29-year-old man with membranous nephropathy that was associated with a sarcoidosic granulomatous tubulointerstitial nephritis, but was without an apparent calcium metabolism disorder. Corticosteroid treatment was associated with remission of nephrotic syndrome. We discuss the relationship between membranous nephropathy and sarcoidosis based on the close appearance of the 2 diseases and the detection of phospholipase A₂ receptor in glomerular immune deposits.
authors.affiliation: Department of Nephrology, Hôpital Tenon, Paris, France.
authors.forename: Masa
authors.initials: M
authors.lastname: Knehtl
authors.forename: Hanna
authors.initials: H
authors.lastname: Debiec
authors.forename: Prochore
authors.initials: P
authors.lastname: Kamgang
authors.forename: Patrice
authors.initials: P
authors.lastname: Callard
authors.forename: Jacques
authors.initials: J
authors.lastname: Cadranel
authors.forename: Pierre
authors.initials: P
authors.lastname: Ronco
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Boffa
mesh_terms: D000328:Adult; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007678:Kidney Glomerulus / Q000378:metabolism; D008297:Male; D009395:Nephritis, Interstitial / Q000150:complications* / Q000175:diagnosis; D054507:Receptors, Phospholipase A2 / Q000032:analysis*; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis
chemical_list: D054507:Receptors, Phospholipase A2