title: [Selective innervation of sacral anterior rootlets to micturition and erection function in rats].
abstract: OBJECTIVE
  To investigate the selective innervation of sacral anterior rootlets to micturition and erection function in SD rats.
  
  
  METHODS
  Forty male SD rats of clean grade, aged 6 weeks old, were selected. Ten rats received a retrograde nerve tract tracing study. Thirty rats were chosen for an electro-physiological study. The L6, S1 spinal cord segment anterior rootlets of anesthetic rats were electrostimulated respectively. The intravesical pressure, urethral perfusion pressure and intracavernous pressure were recorded simultaneously and innervation effectiveness was analyzed.
  
  
  RESULTS
  CB-HRP labeled neurons were observed mainly in L6 and S1 spinal cords. When some anterior rootlets of L6 and S1 were electrostimulated, the intravesical pressure rose gradually, but the urethral perfusion pressure and the intracavernous pressure curve changed slightly; when other rootlets of the same anterior root were stimulated, the urethral perfusion pressure could reach the peak; while others were stimulated, the intracavernous pressure rose quickly, but there were no great changes in intravesical pressure and urethral perfusion pressure. Some other rootlets might lead to the simultaneous changes of 2 or 3 above-mentioned pressures.
  
  
  CONCLUSIONS
  The innervations of L6 and S1 anterior rootlets to rats' bladder detrusor, external urethral sphincter and penile cavernous body are significantly distinct. Different rootlets may be distinguished by microanatomy and electrostimulation.
authors.affiliation: Department of Rehabilitation Medicine, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Wen-ting
authors.initials: WT
authors.lastname: Wang
authors.forename: Mou-wang
authors.initials: MW
authors.lastname: Zhou
authors.forename: Hong-shi
authors.initials: HS
authors.lastname: Huang
authors.forename: Ya-ping
authors.initials: YP
authors.lastname: Chen
authors.forename: Yan-yan
authors.initials: YY
authors.lastname: Yang
authors.forename: Fan-shuo
authors.initials: FS
authors.lastname: Zeng
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D008297:Male; D009130:Muscle, Smooth / Q000294:innervation / Q000502:physiology; D010410:Penile Erection / Q000502:physiology*; D010413:Penis / Q000294:innervation / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013126:Spinal Nerve Roots / Q000502:physiology*; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology; D014554:Urination / Q000502:physiology*