FLT3 internal tandem duplication is associated with a high relapse rate and central nervous system involvement in acute promyelocytic leukemia cases: single institutional analysis.
Haruko
H
Tashiro
Ryosuke
R
Shirasaki
Yoko
Y
Oka
Toshihiko
T
Sugao
Mitsuho
M
Mizutani-Noguchi
Tadashi
T
Yamamoto
Nobu
N
Akiyama
Kazuo
K
Kawasugi
Naoki
N
Shirafuji
D000293:Adolescent; D000328:Adult; D000368:Aged; D016543:Central Nervous System Neoplasms / Q000188:drug therapy / Q000201:enzymology* / Q000235:genetics*; D005260:Female; D020440:Gene Duplication; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy / Q000201:enzymology* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011379:Prognosis; D012008:Recurrence; D020080:Tandem Repeat Sequences; D055815:Young Adult; D051941:fms-Like Tyrosine Kinase 3 / Q000235:genetics*
C497970:FLT3 protein, human; D051941:fms-Like Tyrosine Kinase 3