Effect of a new probiotic Saccharomyces cerevisiae strain on survival of Escherichia coli O157:H7 in a dynamic gastrointestinal model.
Survival of Escherichia coli O157:H7 was investigated using a dynamic gastrointestinal model. A high bacterial mortality was observed in the stomach and duodenum. In contrast, bacteria grew in the distal parts of the small intestine. The coadministration of Saccharomyces cerevisiae CNCM I-3856 led to a significant reduction of bacterial resumption, maybe through ethanol production.
Clermont Université, Centre de Recherche en Nutrition Humaine Auvergne, ERT 18, Conception Ingénierie et Développement de l'Aliment et du Médicament, BP 10448, F-63000 Clermont-Ferrand, France.
Lucie
L
Etienne-Mesmin
Valérie
V
Livrelli
Maud
M
Privat
Sylvain
S
Denis
Jean-Michel
JM
Cardot
Monique
M
Alric
Stéphanie
S
Blanquet-Diot
D000898:Antibiosis; D015169:Colony Count, Microbial; D019453:Escherichia coli O157 / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development*; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D050296:Microbial Viability; D019936:Probiotics / Q000008:administration & dosage* / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000254:growth & development* / Q000378:metabolism
D000431:Ethanol