Recurrence of cluster headache with pramipexole.
Cluster headache (CH) is among the most painful headache disorders. There is still no unifying pathophysiological hypothesis to explain the trigeminal distribution, the circadian periodicity and the autonomic symptoms of the syndrome. We report the case of a patient with worsening of CH following administration of pramipexole for a restless legs syndrome (RLS). This observation supports the hypothesis that the dopaminergic system may play a role in the genesis or trigger of CH.
Cliniques Universitaires UCL de Mont-Godinne, Department of Neurology and Institute of Neuroscience (IoNS) Université Catholique de Louvain, Belgique. michel.ossemann@uclouvain.be
Michel
M
Ossemann
D052160:Benzothiazoles / Q000008:administration & dosage / Q000009:adverse effects*; D003027:Cluster Headache / Q000139:chemically induced* / Q000503:physiopathology; D004298:Dopamine / Q000502:physiology; D018491:Dopamine Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077487:Pramipexole; D012008:Recurrence; D012148:Restless Legs Syndrome / Q000188:drug therapy*
D052160:Benzothiazoles; D018491:Dopamine Agonists; D000077487:Pramipexole; D004298:Dopamine