The development of subjective quality of life over the first 2 years in first-episode psychosis.
The main aim of this study was to examine changes in subjective quality of life (general s-QoL) in patients with first-episode psychosis from baseline to 2 years follow-up. A total of 201 of 252 patients had full quality of life assessment at both baseline and at 2 years. Repeated measure analyses of variance were done to evaluate the development over time, and multiple linear regression analyses to evaluate predictors of change. These patients with a first-episode psychosis showed a significant improvement in general s-QoL during the first 2 years of treatment. Improvements in general s-QoL were associated with increase in excitative symptoms and with improvements in depressive symptoms, global functioning, level of daily activities, level of social activities, and perceived general health.
Department of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. ingrid.melle@medisin.uio.no
Ingrid
I
Melle
Jan Ivar
JI
Røssberg
Inge
I
Joa
Svein
S
Friis
Ulrik
U
Haahr
Jan Olav
JO
Johannessen
Tor Ketil
TK
Larsen
Stein
S
Opjordsmoen
Bjørn Rishovd
BR
Rund
Erik
E
Simonsen
Per
P
Vaglum
Thomas
T
McGlashan
D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D004522:Educational Status; D005260:Female; D006304:Health Status; D006801:Humans; D007398:Interpersonal Relations; D016014:Linear Models; D008297:Male; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D012917:Social Adjustment