A case of recurrent benign lymphocytic (Mollaret's) meningitis and review of the literature.
Mollaret's meningitis is a rare form of benign recurrent aseptic meningitis first described in 1944. We report a case of Mollaret's meningitis due to Herpes Simplex Virus type 2 (HSV2), diagnosed with Polymerase Chain Reaction (PCR) implementation in the Cerebrospinal fluid (CSF) of the patient and treated successfully with acyclovir. To our knowledge, this is the first case of Mollaret's meningitis reported in Greece. We reviewed the literature since PCR has become widely available. Herpes Simplex Virus type 2 has been the most commonly identified causative agent of Mollaret's meningitis.
2nd Department of Internal Medicine, Hellenic Red Cross Hospital, 1 Athanasaki st, 11526 Athens, Greece. panpoulikakos@yahoo.gr
P J
PJ
Poulikakos
E E
EE
Sergi
A S
AS
Margaritis
A G
AG
Kioumourtzis
G D
GD
Kanellopoulos
P K
PK
Mallios
D J
DJ
Dimitrakis
D J
DJ
Poulikakos
A A
AA
Aspiotis
A D
AD
Deliousis
C P
CP
Flevaris
A K
AK
Zacharof
D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D004279:DNA, Viral / Q000134:cerebrospinal fluid; D005260:Female; D006115:Greece; D018258:Herpesvirus 2, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008581:Meningitis; D008582:Meningitis, Aseptic / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D016133:Polymerase Chain Reaction; D012008:Recurrence
D000998:Antiviral Agents; D004279:DNA, Viral; D000212:Acyclovir