Unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: a case report with review of literature.
Basaloid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma of the trachea. We describe the case of an unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy up to a dose of 60 Gy in 33 fractions with weekly paclitaxel and carboplatin. The pathological recognition of basaloid squamous cell carcinoma and its distinction from adenoid cystic carcinoma of the trachea is important for its management. Combining systemic chemotherapy with locoregional radiation is a logical approach to treatment, especially for the basaloid squamous cell carcinoma of the trachea, given its tendency to metastasize early after definitive therapy.
Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
Nikhil P
NP
Joshi
Kunhi Parambath
KP
Haresh
Prasenjit
P
Das
Rajender
R
Kumar
Ramachandran
R
Prabhakar
Daya Nand
DN
Sharma
Puthiyeduthu
P
Heera
Pramod Kumar
PK
Julka
Goura Kishor
GK
Rath
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D014134:Tracheal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*