Five new C21 steroidal glycosides from Periploca sepium.
Five new C(21) steroidal glycosides, named periseosides A-E (1-5), along with six known analogues, were isolated from the root barks of Periploca sepium. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All compounds were evaluated for their immunosuppressive activities.
Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, PR China.
Lei
L
Wang
Zhi-Qi
ZQ
Yin
Qing-Wen
QW
Zhang
Xiao-Qi
XQ
Zhang
Dong-Mei
DM
Zhang
Kang
K
Liu
Yao-Lan
YL
Li
Xin-Sheng
XS
Yao
Wen-Cai
WC
Ye
D000818:Animals; D049109:Cell Proliferation; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007166:Immunosuppressive Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D031109:Periploca / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D006027:Glycosides; D007166:Immunosuppressive Agents; D013256:Steroids