Perioperative complications in patients with left ventricular non-compaction.
OBJECTIVE
Left ventricular non-compaction (LVNC) is a relatively uncommon cardiomyopathy. The implications of the presence of LVNC in the perioperative period are unknown. The objective of this study was to determine the impact of LVNC on post-operative complications.


METHODS
This retrospective cohort study identified patients with an echocardiographic diagnosis of LVNC who had an anaesthetic between 2001 and 2008. For each patient, all surgical procedures during this time were reviewed. Patient demographics, echocardiographic data, details of the procedure and anaesthetic and perioperative complications were recorded. We then compared the rate of perioperative complications in patients with LVNC with established complication rates in the existing literature.


RESULTS
During the study period, 60 patients with LVNC underwent 220 procedures. Nineteen patients experienced a total of 25 complications, of which eight were directly related to the procedure and considered unrelated to LVNC. Of the remaining 17 complications (in 15 patients), there were 10 new arrhythmias, five respiratory complications, one seizure and one episode of syncope. Nearly half (47%) of the complications followed open cardiac surgery with cardiopulmonary bypass. All complications occurred in association with procedures performed under general anaesthesia; none occurred in patients undergoing regional anaesthesia or monitored anaesthesia care (sedation). There was no long-term morbidity and no peri-operative mortality.


CONCLUSIONS
As the awareness and diagnosis of this condition increase, anaesthesiologists will probably care for growing numbers of patients with LVNC. We found that the incidence of post-operative complication in patients with LVNC undergoing a variety of procedures was low and no different from the published complication rates for other patients undergoing similar procedures.
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
Hans P
HP
Sviggum
Sandra L
SL
Kopp
Steven R
SR
Rettke
Kent H
KH
Rehfeldt
D000293:Adolescent; D000328:Adult; D000765:Anesthesia, Conduction / Q000009:adverse effects / Q000379:methods; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods; D015331:Cohort Studies; D004452:Echocardiography; D005260:Female; D006801:Humans; D007223:Infant; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative / Q000009:adverse effects* / Q000379:methods; D055815:Young Adult