Switching around two axles: controlling the configuration and conformation of a hydrazone-based switch.
A hydrazone-based rotary switch, having a quinolinyl stator and a pyridine ring as part of the rotor, can be induced using pH to undergo a four-step switching sequence. This process yields three stable isomers and a fourth "metastable" one that can all be addressed separately based on the sequence of acid and base added. The switching process proceeds via conformational and/or configurational changes, allowing the molecule to rotate around two different axles.
Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States.
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