The renin angiotensin system and the metabolic syndrome.
The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin.
Department of Pathology and Laboratory Medicine The University of North Carolina at Chapel Hill Chapel Hill, NC 27599-7525.
Chih-Hong
CH
Wang
Feng
F
Li
Nobuyuki
N
Takahashi