Hospital surveillance of childhood bacterial meningitis in Senegal and the introduction of Haemophilus influenzae type b conjugate vaccine.
Bacterial meningitis is an important cause of morbidity and mortality in children living in low-resource settings. Pediatric bacterial meningitis cases < 5 years of age were identified through a regional hospital surveillance system for 3 years after introduction of routine immunization with Haemophilus influenzae type b (Hib) conjugate vaccine in Senegal in July 2005. Cases from the national pediatric hospital were also tracked from 2002 to 2008. The regional surveillance system recorded 1,711 suspected pediatric bacterial meningitis cases. Of 214 laboratory-confirmed cases, 108 (50%) were caused by Streptococcus pneumoniae, 42 (20%) to Hib, and 13 (6%) to Neisseria meningitidis. There was a 98% reduction in the number of hospitalized Hib meningitis cases from Dakar Region in 2008 compared with 2002. The surveillance system provides important information to the Ministry of Health as they consider self-funding Hib vaccine and introducing pneumococcal vaccine.
PATH, Dakar, Senegal. ousseynouba1@gmail.com
Osseynou
O
Ba
Jessica A
JA
Fleming
Yakou
Y
Dieye
Boniface Mutombo
BM
wa Mutombo
Mamadou
M
Ba
Moussa Fafa
MF
Cisse
Aissatou Gaye
AG
Diallo
Iyane
I
Sow
Mary P E
MP
Slack
Pape Coumba
PC
Faye
Mady
M
Ba
Ndiouga
N
Diallo
Noel S
NS
Weiss
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D018073:Haemophilus Vaccines / Q000276:immunology*; D006761:Hospitals; D006801:Humans; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D011159:Population Surveillance; D012675:Senegal / Q000453:epidemiology; D013997:Time Factors; D018074:Vaccines, Conjugate / Q000276:immunology
D000900:Anti-Bacterial Agents; D018073:Haemophilus Vaccines; D018074:Vaccines, Conjugate