[Quorum sensing mechanism as a factor regulating virulence of Gram-negative bacteria].
The metabolism of a high density population of bacteria is regulated by a quorum sensing mechanism. Cell-to-cell communication of microorganisms regulates the process of production of pathogenicity factors including formation and differentiation of bacterial biofilms. The role of the quorum sensing system in the expression of virulence features is described in this paper. The possibility of application of the quorum sensing mechanism in medicine is also discussed.
Katedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu, ul. Wojska Polskiego 48, 60-627 Poznań. kmyszka@up.poznan.pl
Kamila
K
Myszka
Katarzyna
K
Czaczyk
D018441:Biofilms; D006090:Gram-Negative Bacteria / Q000472:pathogenicity* / Q000502:physiology*; D006801:Humans; D053038:Quorum Sensing / Q000502:physiology*; D014774:Virulence