Vaginal Lymphoma with Immune Thrombocytopenic Purpura: An Unusual Case Report.
The female genital tract is rarely the initial site of presentation in lymphoma or leukemia. We report a case of non-Hodgkin's lymphoma (NHL) presenting initially in the vagina. The patient, a 75-year-old woman, had a history of immune thrombocytopenic purpura (ITP). She presented with a chief complaint of genital bleeding and introital pain. On transvaginal ultrasonography, a vaginal tumor with an irregular wall was detected, and the internal echo showed a hypoechoic and echogenic pattern. Ultrasonography and magnetic resonance imaging (MRI) suggested that the vaginal tumor was likely to be a hematoma or a hemorrhagic tumor arising from ITP. Incision and resection for a hematoma or a hemorrhagic tumor were carried out in response to genital bleeding, introital pain, and pathological diagnosis. Postoperative microscopic examination confirmed that the tumor was a vaginal NHL. The final diagnosis using the Ann Arbor staging system was high-stage (stage IV) NHL. The patient received chemotherapy, and she remains in remission for 42 months after treatment.
Department of Obstetrics and Gynecology, Kansai Medical University, Moriguchi, Kadoma, Japan.
Akiko
A
Ikuta
Yoshiaki
Y
Tanaka
Tomoko
T
Tsuzuki
Shoko
S
Tsuji
Genichiro
G
Sumi
Tomomi
T
Mizokami
Hisahide
H
Sugimoto
Nobuaki
N
Shikata
Katsuhiko
K
Yasuda
Yorihiko
Y
Horikoshi
Hideharu
H
Kanzaki