[Personalized medicine in haematooncology--the pathologist's perspective].
The concept of personalized medicine is not only an individualized therapeutic management of a patient; its prerequisite is an individualized approach to diagnosis. Most of oncological diagnoses and a many prognostic features are provided by a pathologists. The pathologist uses not only basic histological methods, but also a morphoproteomic and morphogenomic approaches. Integral part of a contemporary oncological diagnosis is a molecular investigation of a tumour, which can both prove the presence of molecules suitable for targeted therapy, and design a molecular "patient-specific" marker for minimal residual disease monitoring.
Univerzita Karlova v Praze, 2, lékarská fakulta, Ustav patologie a molekulární medicíny Motol, Praha. vcampr@yahoo.com
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D019337:Hematologic Neoplasms / Q000473:pathology / Q000628:therapy*; D006801:Humans; D058990:Molecular Targeted Therapy; D057285:Precision Medicine; D011379:Prognosis