Gold-catalysed rearrangement of O-vinyl oximes for the synthesis of highly substituted pyrroles.
O-Vinyl oximes were synthesised from the reaction of oximes with activated alkynes and subsequently rearranged using gold catalysis to afford highly substituted pyrroles in an efficient and regiocontrolled process. Additionally, pyrroles were formed directly from oximes and activated alkynes in a multifaceted catalysis process.
School of Chemistry, University of Nottingham, Nottingham, NG7 2RD, UK.
Simbarashe
S
Ngwerume
Jason E
JE
Camp
D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D008956:Models, Chemical; D010091:Oximes / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
D000480:Alkynes; D010091:Oximes; D011758:Pyrroles; D014753:Vinyl Compounds; D006046:Gold