Aphanamolide A, a new limonoid from Aphanamixis polystachya.
Two new limonoids, namely aphanamolides A (1) and B (2), were isolated from the seeds of Aphanamixis polystachya . Their structures were established by spectroscopic methods. Aphanamolide A (1) featured an unprecedented carbon skeleton via the formation of a C-3-C-6 bond. Compounds 1 and 2 showed cytotoxic activity against two tumor cell lines.
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, People's Republic of China.
Sheng-Ping
SP
Yang
Hua-Dong
HD
Chen
Shang-Gao
SG
Liao
Bo-Jun
BJ
Xie
Ze-Hong
ZH
Miao
Jian-Min
JM
Yue
D036701:Limonins / Q000737:chemistry*; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure
D036701:Limonins; C555750:aphanamolide A