Lactobacillus plantarum extracellular chitin-binding protein and its role in the interaction between chitin, Caco-2 cells, and mucin.
In the present work, we describe the adhesion capabilities of a recombinant Lactococcus lactis strain producing an extracellular protein from Lactobacillus plantarum. Our results show that this protein may offer the bacterium a mechanism to bind to N-acetylglucosamine-containing polymers, such as human mucins, present in different environments.
Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas, Ctra. Infiesto s/n, 33300 Villaviciosa, Asturias, Spain. borja@ipla.csic.es
Borja
B
Sánchez
Carmen
C
González-Tejedo
Patricia
P
Ruas-Madiedo
María C
MC
Urdaci
Abelardo
A
Margolles
D018829:Adhesins, Bacterial / Q000378:metabolism*; D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D018938:Caco-2 Cells / Q000378:metabolism*; D002686:Chitin / Q000378:metabolism*; D006801:Humans; D048191:Lactiplantibacillus plantarum / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D013294:Lactococcus lactis / Q000235:genetics / Q000378:metabolism; D009077:Mucins / Q000378:metabolism*; D011485:Protein Binding; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism
D018829:Adhesins, Bacterial; D001426:Bacterial Proteins; D009077:Mucins; D011994:Recombinant Proteins; D002686:Chitin