The influence of maternal age on pregnancy outcome in nulliparous women with twin gestation.
We sought to determine if outcomes of nulliparous twin pregnancies differ based on maternal age. Nulliparous women with current twin pregnancies were identified from a database of women enrolled for outpatient nursing surveillance. Data were stratified into four groups by maternal age: less than 20, 20 to 34, 35 to 39, and greater than or equal to 40 years. Maternal and neonatal outcomes for women less than 20, 35 to 39, and 40 or more were compared with 20- to 34-year-old controls using Kruskal-Wallis, Mann-Whitney, and Pearson chi-square analyses. We analyzed 2144 nulliparous twin pregnancies. Patients ≥35 years (34 to 39, 78.5% or ≥40, 85.9%) were more likely to have cesarean deliveries compared with controls 20 to 34 years old (71.2%). Women aged 35 to 39 were less likely to deliver at <37 weeks, and women in the ≥40 group were less likely to deliver at <35 weeks due to spontaneous preterm labor compared with the controls. Neonates born to women aged 35 to 39 had a greater gestational age at delivery and larger average birth weight than controls. Maternal and neonatal outcomes were not adversely influenced by advanced maternal age in nulliparous women carrying twin gestations.
Department of Obstetrics and Gynecology, University of Miami, Miami, Florida, USA.
Anupama S Q
AS
Kathiresan
Luis E
LE
Roca
Niki
N
Istwan
Cheryl
C
Desch
Yvette C
YC
Cordova
Felipe José
FJ
Tudela
Victor H
VH
Gonzalez-Quintero
D000328:Adult; D001724:Birth Weight; D002585:Cesarean Section; D016009:Chi-Square Distribution; D005260:Female; D005865:Gestational Age; D006801:Humans; D008423:Maternal Age; D007752:Obstetric Labor, Premature; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D018709:Statistics, Nonparametric; D014427:Twins; D055815:Young Adult