Percutaneous injection of chemotherapeutic drugs in the guidance of magnetic resonance imaging for the treatment of cholangiocarcinoma.
The morbidity and mortality of cholangiocarcinoma have been rising yearly. However, conventional therapies still cannot achieve a satisfactory survival rate. Furthermore, there is an urgent need to discover new approaches to overcome chemotherapeutic drug resistance of cholangiocarcinoma. Considering the unique advantage of magnetic irradiation, we hypothesize that percutaneous injection of chemotherapeutic drugs in the guidance of nuclear magnetic resonance imaging may enhance the survival rate of cholangiocarcinoma without increasing undesired side effects.
Department of Surgery, Shanghai Jiao Tong University, Affiliated Sixth People's Hospital, Shanghai, China.
Zhi-Hua
ZH
Liu
Peng
P
Zhang
Yu-Kun
YK
Zhou
Huan-Long
HL
Qin
D000279:Administration, Cutaneous; D001650:Bile Duct Neoplasms / Q000188:drug therapy*; D017734:Bile Ducts, Extrahepatic; D018281:Cholangiocarcinoma / Q000188:drug therapy*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*