Platelet aggregation and endothelial function in patients with complicated essential hypertension (ischemic stroke) and coronary heart disease.
In patients with complicated essential hypertension (ischemic stroke) and coronary heart disease, inductors of platelet aggregation in various doses induced "paradoxical" changes in platelet aggregation activity reflecting the degree of decompensation under conditions of persistent endothelial dysfunction. Aggregation inductors in low doses were shown to have a greater diagnostic significance. The content of endothelial dysfunction markers in the blood was persistently elevated under these conditions.
V. F. Voino-Yasenetskii Krasnoyarsk State Medical University, Krasnoyarsk, Russia. doctorkardiolog99@rambler.ru
N Yu
NY
Shimohina
M M
MM
Petrova
A A
AA
Savchenko
E G
EG
Smertina
V G
VG
Ionova
M M
MM
Tanashyan
D000244:Adenosine Diphosphate; D003327:Coronary Disease / Q000097:blood*; D004730:Endothelium, Vascular / Q000502:physiology*; D004837:Epinephrine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology*; D018709:Statistics, Nonparametric; D020521:Stroke / Q000097:blood*; D014841:von Willebrand Factor / Q000032:analysis
D014841:von Willebrand Factor; D000244:Adenosine Diphosphate; D004837:Epinephrine