Lucigenin- and luminol-dependent chemiluminescence of blood neutrophils in patients with renal cancer.
High basal production of primary active oxygen forms was detected in the peripheral blood neutrophils of patients with renal cell cancer. In vitro stimulation of neutrophils led to more rapid release of superoxide radicals into extracellular space and to a reduction of cell capacity to more intense production of primary active oxygen forms.
V. F. Voino-Yasenetsky State Medical University, Krasnoyarsk, Russia.
E A
EA
Shkapova
L M
LM
Kurtasova
A A
AA
Savchenko
D000166:Acridines / Q000378:metabolism; D000328:Adult; D006801:Humans; D007680:Kidney Neoplasms / Q000097:blood*; D049408:Luminescent Agents / Q000378:metabolism; D008163:Luminescent Measurements; D008165:Luminol / Q000378:metabolism; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*
D000166:Acridines; D049408:Luminescent Agents; D017382:Reactive Oxygen Species; C033472:10,10'-dimethyl-9,9'-biacridinium; D008165:Luminol; D010100:Oxygen