AL amyloidosis in a young adult: remission with autologous stem cell transplantation.
Autologous stem cell transplant is one of the therapies employed in the treatment of primary amyloidosis or AL. The authors report on a 46-year-old patient with bilateral periorbital hematomas, macroglossia who presented, during the investigation, IgG-Kappa paraprotein in serum. The diagnosis of primary amyloidosis or AL was confirmed and the treatment proposed consisted of high-dose melphalan as conditioning regimen before autologous stem cell transplant, which determined complete remission of the disease, along with the disappearance of clinical signs and absence of the monoclonal component.
Centro de Pesquisa Clínica Hospital Abreu Sodré- AACD. ricardogolmia@brturbo.com.br
Ricardo Prado
RP
Golmia
Isabel Clapis
IC
Bello
Eliane
E
Rosseto
João Carlos Campos
JC
Guerra
Cristóvão
C
Mangueira
Morton Aaron
MA
Scheinberg
D000686:Amyloidosis / Q000601:surgery; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D033581:Stem Cell Transplantation