Primary bone lymphoma: a report of two cases and review of the literature.
Primary bone lymphoma (PBL) is an uncommon tumor accounting for approximately 4-5% of extra nodal lymphoma and less than 1% of all non-Hodgkin's lymphoma. Disease may be complicated at presentation by pathological fracture or spinal cord compression. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL. Owing to its rarity, only a few retrospective studies have been published addressing the prognosis and treatment of primary bone lymphoma. In this paper, we report our experience with two cases of PBL treated with chemotherapy and radiotherapy and review literature to elucidate the optimal treatment of primary bone lymphoma.
Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore 560 030, India. drtejinderseera@gmail.com
Tejinder
T
Singh
C T
CT
Satheesh
K C
KC
Lakshmaiah
T M
TM
Suresh
Govind K
GK
Babu
D
D
Lokanatha
Linu A
LA
Jacob
Rajashekar
R
Halkud
D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed