[Analyze the antibody level of enterovirus 71 about children cases of hand-foot-mouse disease outbreak].
OBJECTIVE
To analyze the Enterovirus 71 infectious status about probably cases of hand-foot-mouse disease (HFMD).


METHODS
Collect the blood samples of HFDM children probably cases and test the IgG, IgM antibody by ELISA, analyzed the age and gender distribution.


RESULTS
We collected 159 blood samples of children probably cases who are 1 to 5 years old. The average EV71 IgG positive rate is 63.5%, which of IgM is 12.0%. The positive rate of EV71 IgG is decrease by aged. Male's EV71 IgM positive rate is higher than female's significantly.


CONCLUSIONS
The pathogen of this case of HFMD outbreak is EV71. Male's EV7l infectious and incidence are higher than female's. The result of this investigation could provide information to HFMD disease control.
Heze City Blood Center, Shandong Province, China.
Kun
K
Ju
Lin-En
LE
Jiang
Wei
W
Li
Hui-Qing
HQ
Ren
Xu-Hua
XH
Jing
Bao-Hui
BH
Jin
D002675:Child, Preschool; D004770:Enterovirus / Q000276:immunology* / Q000472:pathogenicity*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006232:Hand, Foot and Mouth Disease / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007223:Infant; D008297:Male
D007074:Immunoglobulin G; D007075:Immunoglobulin M