Defining MAPK interactomes.
The mitogen-activated protein kinase (MAPK) signaling network is integrated into most, if not all, defined homeostatic and regulatory responses of eukaryotic cells. A systematic experimental and computational approach has been used to identify more than 2,000 protein interactions related to functions and regulation of the MAPK signaling network. This discovery process provides a rich data and reagent resource for defining complexities of protein networks involving MAPKs and control of cellular physiology.
Department of Pharmacology, University of North Carolina, Chapel Hill, 27599, United States. glj@med.unc.edu
Gary L
GL
Johnson
D020935:MAP Kinase Signaling System / Q000502:physiology*; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology
D020928:Mitogen-Activated Protein Kinases