A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control.
OBJECTIVE
the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis.


METHODS
this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with moderate-to-severe periodontal disease were assigned to either a periodontal treatment arm, consisting of scaling and root planing (intervention group [IG]), or a delayed treatment arm that received periodontal care after 6 months (control group [CG]). Periodontal parameters and glycosylated haemoglobin (A1C) were evaluated at 1, 3 and 6 months.


RESULTS
all periodontal parameters improved significantly in the IG. A1C levels decreased statistically significantly more in the IG versus the CG (0.72%versus 0.13%; p<0.01) independently of other confounders.


CONCLUSIONS
this study provides evidence that periodontal treatment contributes to improved glycaemic control in type 2 diabetes mellitus patients. Larger controlled trials are needed to confirm if this finding is generalizable to other populations of patients with type 2 diabetes.
Department of Periodontology, School of Dentistry, University of Athens, Athens, Greece. pkoroman@yahoo.com
Panagiotis A
PA
Koromantzos
Konstantinos
K
Makrilakis
Xanthippi
X
Dereka
Nicholas
N
Katsilambros
Ioannis A
IA
Vrotsos
Phoebus N
PN
Madianos
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D012534:Dental Scaling; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000097:blood / Q000150:complications / Q000473:pathology / Q000628:therapy*; D010512:Periodontal Index; D011446:Prospective Studies; D012720:Severity of Illness Index; D016037:Single-Blind Method; D018709:Statistics, Nonparametric; D016896:Treatment Outcome
D001786:Blood Glucose; D006442:Glycated Hemoglobin