A case of nephrotic syndrome with Gitelman's syndrome.
Nephrotic syndrome, though common in children, association of it with Gitelman's syndrome (GS) is a rare occurrence. Very few cases have been reported in the medical literature so far. Here we report a case of nephrotic syndrome with frequent relapses and remissions on intermittent steroid and diuretic therapy. Patient was restarted on steroids and frusemide. Puffiness of face, bipedal edema and oliguria improved but patient developed tingling numbness in both limbs, perioral numbness and carpopedal spasm. On investigation she was found to have proteinuria, metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia and hyperreninemia with normal blood pressure.
Department of Medicine, Lokmanya Tilak Municipal Medical College And General Hospital, Sion, Mumbai 400 022.
Dharmendra B
DB
Pandey
Sangeeta J
SJ
Pednekar
Swati A
SA
Chavan
Deepa
D
Korivi
Amit Kumar
AK
Shah
Uday P
UP
Kulkarni
D000471:Alkalosis / Q000150:complications / Q000188:drug therapy; D004358:Drug Therapy; D005260:Female; D053579:Gitelman Syndrome / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006996:Hypocalcemia / Q000150:complications / Q000188:drug therapy; D007008:Hypokalemia / Q000150:complications / Q000188:drug therapy; D008274:Magnesium / Q000097:blood; D009404:Nephrotic Syndrome / Q000150:complications* / Q000188:drug therapy; D011507:Proteinuria / Q000150:complications* / Q000188:drug therapy; D012083:Renin / Q000097:blood; D013577:Syndrome; D013746:Tetany / Q000150:complications; D016896:Treatment Outcome; D055815:Young Adult
D012083:Renin; D008274:Magnesium