Initial experience with off-pump left ventricular assist device implantation in single center: retrospective analysis.
BACKGROUND
We hypothesize that implantation of left ventricular assist device through off-pump technique is feasible and has a comparable result to implantation on cardiopulmonary bypass and could improve one-year survival.


METHODS
This retrospective, observational, single-center study was conducted on 29 consecutive patients at our institution who underwent off-pump left ventricular assist device implantation by a single surgeon.


RESULTS
Twenty-seven procedures were performed successfully using the off-pump technique. The survival rate was 92% at 30 days, 76% at 90 days, and 67% at one year. We compared the one-year survival of different implantation periods, and divided our study into three time intervals (2004-2005, 2006, and 2007). There was a trend in reduction in number of deaths over one year that demonstrated a decrease in death rate from 50% to 17%, as well as improvement in our experience over time. However, this trend is not statistically significant (p = 0.08) due to limited sample size.


CONCLUSIONS
Based upon our findings, off-pump left ventricular assist device implantation is a feasible surgical technique, and combining this technique with improved device technology in the future may provide even greater improvement in patient outcomes.
The Ohio State University Medical Center, Department of Anesthesiology, Columbus, 43210, USA. Hamdy.Elsayed-Awad@osumc.edu
Hamdy
H
Awad
Mohamed
M
Abd El Dayem
Jarrett
J
Heard
Galina
G
Dimitrova
Lianbo
L
Yu
Benjamin C
BC
Sun
D000328:Adult; D002302:Cardiac Output; D002315:Cardiopulmonary Bypass; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D006333:Heart Failure / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D016896:Treatment Outcome