Cardiac arrhythmia: a simple conceptual framework.
This review presents a simple trigger-substrate model of arrhythmogenesis and its application to the generation of reentrant ventricular arrhythmias. We demonstrate its broad applicability to the understanding of arrhythmic phenomena in a wide range of both hereditary and acquired arrhythmic disorders.
John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.
Asli
A
Kalin
Juliet
J
Usher-Smith
Victoria J
VJ
Jones
Christopher L-H
CL
Huang
Ian N
IN
Sabir
D000200:Action Potentials; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology* / Q000503:physiopathology; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D012307:Risk Factors; D013997:Time Factors