Nonantibiotic therapy for multidrug-resistant Pseudomonas aeruginosa in a patient with chronic burn wounds.
The authors report a special case of nonantibiotic therapy in a adolescent boy with chronically infected wounds induced by inappropriate use of antibiotics. The result of microbial cultures of the secretions on the wounds indicated that the infection of multidrug-resistant Pseudomonas aeruginosa was resistant to aminoglycoside and cephalosporin but sensitive to carbapenem and quinolones. We formulated a management strategy including daily hydrotherapy, thermal radiation therapy, balanced fluid and electrolytes and intermittent transfusion of blood products, but antibiotics were not used. Twenty-four days after his hospitalization, an autologous split-meshed skin grafting was successfully performed. He was followed up for 6 months after discharge; both lower extremities had an excellent functional recovery. The therapy introduced in this report may be beneficial for chronic infected wounds.
Department of Burns Surgery, The First Hospital Jilin University, Changchun, Jilin, People's Republic of China.
Zhenhai
Z
Niu
Jiaao
J
Yu
Zhenghua
Z
Jin
Jingchun
J
Zhao
Kai
K
Shi
Jiqiang
J
Liu
D000293:Adolescent; D002056:Burns / Q000150:complications*; D002908:Chronic Disease; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000628:therapy*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*