Multiple sclerosis: Mechanisms of disability accumulation in multiple sclerosis.
Natural history studies have identified numerous features of disability progression in patients with multiple sclerosis (MS), and have provided valuable insight into the underlying pathology of the disease that could assist the development of new treatment strategies. A new study indicates that disability progression occurs in two stages in patients with MS.
Mellen Center for MS Treatment and Research, Neurological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue/U10, Cleveland, OH 44195, USA.
Devon S
DS
Conway
Jeffrey A
JA
Cohen
D004185:Disability Evaluation; D018450:Disease Progression; D006801:Humans; D009103:Multiple Sclerosis / Q000473:pathology* / Q000503:physiopathology*