Autoimmune diseases co-existing with hepatitis C virus infection.
Autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. Hepatitis C virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis C virus infection and some autoimmune disease has been studied. For some of these disorders their association with hepatitis C virus infection is well recognized while for others it remains probable or weak. Examples of autoimmune phenomena observed in chronic hepatitis C virus infection include rheumatoid arthritis, thyroid disease, cryoglobulinaemia, immune thrombocytopenic purpura, systemic lupus erythematosus and sjogren syndrome. To date, the etiological role and the pathogenetic involvement of the hepatitis C infection remains unknown.The aim of this study is to assess the presence of different autoimmune manifestations of hepatitis C virus infection reported in literature.
Department of Immunology, School of Public Health, Tehran University of Medical Sciences. Tehran, Iran. zjadali@razi.tums.ac.ir
Zohreh
Z
Jadali
Seyed-Moayed
SM
Alavian
D001327:Autoimmune Diseases / Q000150:complications* / Q000276:immunology; D004700:Endocrine System Diseases / Q000150:complications / Q000276:immunology; D006402:Hematologic Diseases / Q000150:complications / Q000276:immunology; D016174:Hepacivirus / Q000276:immunology; D006526:Hepatitis C / Q000150:complications* / Q000276:immunology; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000150:complications / Q000276:immunology; D007674:Kidney Diseases / Q000150:complications / Q000276:immunology; D009422:Nervous System Diseases / Q000150:complications / Q000276:immunology; D012216:Rheumatic Diseases / Q000150:complications / Q000276:immunology; D012871:Skin Diseases / Q000150:complications / Q000276:immunology