Pulmonary thin-section CT findings in acute Moraxella catarrhalis pulmonary infection.
OBJECTIVE
Moraxella catarrhalis is an important pathogen in the exacerbation of chronic obstructive pulmonary disease. The aim of this study was to assess the clinical and pulmonary thin-section CT findings in patients with acute M. catarrhalis pulmonary infection.


METHODS
Thin-section CT scans obtained between January 2004 and March 2009 from 292 patients with acute M. catarrhalis pulmonary infection were retrospectively evaluated. Clinical and pulmonary CT findings in the patients were assessed. Patients with concurrent infection including Streptococcus pneumoniae (n = 72), Haemophilus influenzae (n = 61) or multiple pathogens were excluded from this study.


RESULTS
The study group comprised 109 patients (66 male, 43 female; age range 28-102 years; mean age 74.9 years). Among the 109 patients, 34 had community-acquired and 75 had nosocomial infections. Underlying diseases included pulmonary emphysema (n = 74), cardiovascular disease (n = 44) or malignant disease (n = 41). Abnormal findings were seen on CT scans in all patients and included ground-glass opacity (n = 99), bronchial wall thickening (n = 85) and centrilobular nodules (n = 79). These abnormalities were predominantly seen in the peripheral lung parenchyma (n = 99). Pleural effusion was found in eight patients. No patients had mediastinal and/or hilar lymph node enlargement.


CONCLUSIONS
M. catarrhalis pulmonary infection was observed in elderly patients, often in combination with pulmonary emphysema. CT manifestations of infection were mainly ground-glass opacity, bronchial wall thickening and centilobular nodules.
Department of Radiology, Faculty of Medicine, Oita University, Oita, Japan. fumitook@med.oita-u.ac.jp
F
F
Okada
Y
Y
Ando
T
T
Nakayama
S
S
Tanoue
R
R
Ishii
A
A
Ono
M
M
Watanabe
H
H
Takaki
T
T
Maeda
H
H
Mori
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017714:Community-Acquired Infections / Q000000981:diagnostic imaging; D003428:Cross Infection / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D001936:Moraxella catarrhalis / Q000302:isolation & purification* / Q000472:pathogenicity; D045828:Moraxellaceae Infections / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D011014:Pneumonia / Q000150:complications / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000473:pathology; D029424:Pulmonary Disease, Chronic Obstructive / Q000000981:diagnostic imaging* / Q000473:pathology; D011656:Pulmonary Emphysema / Q000150:complications / Q000000981:diagnostic imaging*; D013902:Radiography, Thoracic / Q000379:methods; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods