[Distribution characteristics of colorectal neoplasm in 4450 patients and implication for colorectal cancer screening].
OBJECTIVE
To study the distribution characteristics of colorectal neoplasm and evaluate the implication for colorectal cancer screening.


METHODS
A total of 17,939 colonoscopies were performed in the National Center of Colorectal Surgery between October 2004 and June 2009. Characteristics of colorectal neoplasm including anatomical distribution, sex, and age were investigated.


RESULTS
Colorectal neoplasm was found in 24.8% (4450/17,939) of the patients during colonoscopy, including adenomatous polyp (n=3410, 19.0%) and adenocarcinoma (n=1040, 5.8%). The prevalence of colorectal neoplasm was higher in male and significantly increased in patients older than 40 years. 63.3% of the lesions located at the distal colon (sigmoid colon and rectum) and 36.7% at the proximal colon (36.7%). In patients with adenomatous polyp, 52.8% (1802/3410) of the lesions were at the distal colon, 30.8% (1049/3410) at the proximal colon, and 16.4% (559/3410) at both distal and proximal colon. In patients with carcinoma (n=1040), 921 (88.6%) lesions located at the distal colon, 118 (11.3%) at the proximal colon, and 1 (0.1%) at both segments.


CONCLUSIONS
Sigmoidoscopy is inadequate for colorectal cancer screening as compared to colonoscopy.
Center of Colorectal, The Third Affiliated Hospital, Nanjing University of Traditional Chinese Medicine, Nanjing 210001, China.
Qiang
Q
Leng
Kun-lan
KL
Wu
Hei-ying
HY
Jin
Ping
P
Liu
Hui-ping
HP
Lin
Jin-hao
JH
Zhang
Hui
H
Ye
Yong
Y
Zhu
Jin-chun
JC
Zhang
D000328:Adult; D017677:Age Distribution; D000368:Aged; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017678:Sex Distribution