Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain.
Division of Experimental Medicine, Imperial College London, London W12 0NN, United Kingdom.
David R J
DR
Owen
Andrew J M
AJ
Lewis
Richard
R
Reynolds
Rainer
R
Rupprecht
Daniela
D
Eser
Martin R
MR
Wilkins
Idriss
I
Bennacef
David J
DJ
Nutt
Christine A
CA
Parker
D014151:Anti-Anxiety Agents / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D006801:Humans; D011485:Protein Binding; D011687:Purines / Q000378:metabolism*; D018079:Receptors, GABA / Q000378:metabolism*
D014151:Anti-Anxiety Agents; C502525:N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide; D011687:Purines; D018079:Receptors, GABA; C499229:TSPO protein, human