Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance' by Calabrese et al.
Resveratrol, a grape skin and red wine-derived polyphenolic phytoalexin, exhibits hormetic action delivering numerous health benefits at lower doses while being detrimental at higher doses. Epidemiologic and clinical trials need to be based on the clear understanding of hormetic health benefits of resveratrol.
Cardiovascular Research Center, University of Connecticut, Farmington, CT 06030, USA. ddas@neuron.uchc.edu
Dipak K
DK
Das
D000818:Animals; D035843:Biomedical Research; D002316:Cardiotonic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D002319:Cardiovascular System / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D000077185:Resveratrol; D013267:Stilbenes / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D014920:Wine
D002316:Cardiotonic Agents; D013267:Stilbenes; D000077185:Resveratrol