An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?
Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Cristina
C
Avonto
Orazio
O
Taglialatela-Scafati
Federica
F
Pollastro
Alberto
A
Minassi
Vincenzo
V
Di Marzo
Luciano
L
De Petrocellis
Giovanni
G
Appendino
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry; D002460:Cell Line; D003543:Cysteamine / Q000737:chemistry; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D055808:Drug Discovery; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D000970:Antineoplastic Agents; D001688:Biological Products; D013438:Sulfhydryl Compounds; D003543:Cysteamine; D004121:Dimethyl Sulfoxide