[Kidney biopsy in Mantua: 2000-2009 report].
The aim of this study was to report the frequency of kidney diseases related to gender, age, clinical presentation and renal function at the time of kidney biopsy in the population of Mantua province (400,000 residents). We collected the results of 132 real-time ultrasound-guided fine-needle (18 G) kidney biopsies by optical and immunofluorescence microscopy. The clinical presentation at the time of biopsy was nephrotic syndrome in 57%, nephritic syndrome in 22%, and urinary abnormalities in 21% of cases. Serum creatinine was >-1.5 mg/dL in 48% of patients. Membranous nephropathy was the most frequent histological finding (21.4%), followed by IgA nephropathy (14.5%), focal glomerulosclerosis (11.5%), diabetic nephropathy (8.4%), and chronic interstitial nephritis (6.9%). Primary glomerulonephritis including membranous glomerulonephritis and IgA nephropathy showed a male predominance. The pathological correlations in native biopsy-proven renal disease provided useful information for clinical practice. The histological findings in our patient series are similar to those recorded in Italian and European registries. A less invasive policy in the case of isolated urinary abnormalities and a normal eGFR resulted in a lower incidence of IgA nephropathy in our series than was recorded in the national Italian registry.
Dipartimento Specialita' Mediche, Struttura Complessa di Nefrologia e Dialisi, A.O. C. Poma, Mantova, Italy. domenica.lambertini@aopoma.it
Domenica
D
Lambertini
Paola
P
Brescia
Alessia
A
Serra
Pierluigi
P
Botti
Giorgio
G
Ferrari
Chiara
C
Baraldi
Cosimo Damiano
CD
Marseglia
Luigi
L
Gaetti
Renzo
R
Tarchini
D000328:Adult; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D007558:Italy; D007674:Kidney Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged