New hopane triterpenes and antioxidant constituents from Potentilla fulgens.
Phytochemical investigation of the aerial parts of Potentilla fulgens L. led to the isolation of two new triterpenes, potentene A (1) and potentene B (2). In addition, three known compounds afzelchin-4alpha --> 8"-catechin (3), epiafzelchin (4) and rutin (5) were isolated. The structures of all these compounds were elucidated by extensive spectroscopic and chemical evidence. Compounds 3, 4, and 5 exhibited significant 1,1,diphenyl-2-picrylhydrazyl radical scavenging activity, with IC50 values of 1.21, 2.88 and 5.20 mg/mL, respectively; the known standard antioxidant, vitamin C, had a value of 0.44 mg/mL.
Natural Plants Product Division, Institute of Himalyan Bioresource Technology (CSIR), Palampur (H.P) 176 061, India.
Vikas
V
Jaitak
Vijay K
VK
Kaul
Himlata
Neeraj
N
Kumar
Bikram
B
Singh
Jyoti
J
Dhar
Om P
OP
Sharma
D000975:Antioxidants / Q000302:isolation & purification*; D002392:Catechin / Q000031:analogs & derivatives / Q000302:isolation & purification; D005419:Flavonoids / Q000302:isolation & purification; D031987:Potentilla / Q000737:chemistry*; D012431:Rutin / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D000975:Antioxidants; D005419:Flavonoids; D014315:Triterpenes; C554757:afzelchin-4'-8''-catechin; C120647:epiafzelechin; C025206:hopane; D012431:Rutin; D002392:Catechin