Significant differences between serum CRP levels in children in different categories of physical activity: the PLAY study.
Low-grade systemic inflammation is emerging as a component of the metabolic syndrome. The purpose of this study was to assess the association between serum C-reactive protein (CRP), physical activity and body composition in 193 black children aged 13 to 18 years from a South African township. Demographic information and anthropometric measurements were taken, and fasting blood samples were analysed for high-sensitivity serum CRP. Body fat was measured by air displacement plethysmography. There was a trend towards higher serum CRP in the boys with a higher percentage body fat. After multiple regression analyses, waist circumference in the girls was significantly associated with serum CRP. In the boys, there was an inverse correlation between percentage body fat and fitness, and between fitness and serum CRP. Significant differences were found between serum CRP in the different physical activity categories, with lower serum CRP in the girls in the higher physical activity group. Obesity should be prevented in South African children by encouraging physical activity.
School of Physiology, Nutrition and Consumer Science, North-West University, Potchefstroom, South Africa.
B
B
Harmse
H S
HS
Kruger
D050154:Adiposity / Q000208:ethnology; D000293:Adolescent; D015415:Biomarkers / Q000032:analysis; D044383:Black People / Q000706:statistics & numerical data*; D002097:C-Reactive Protein / Q000032:analysis*; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood / Q000208:ethnology* / Q000503:physiopathology / Q000517:prevention & control; D010991:Plethysmography; D057185:Sedentary Behavior / Q000208:ethnology*; D012737:Sex Factors; D013019:South Africa / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data; D055105:Waist Circumference
D015415:Biomarkers; D018836:Inflammation Mediators; D002097:C-Reactive Protein