Incremental value of clinical data beyond claims data in predicting 30-day outcomes after heart failure hospitalization.
BACKGROUND
Administrative claims data are used routinely for risk adjustment and hospital profiling for heart failure outcomes. As clinical data become more readily available, the incremental value of adding clinical data to claims-based models of mortality and readmission is unclear.


RESULTS
We linked heart failure hospitalizations from the Get With The Guidelines-Heart Failure registry with Medicare claims data for patients discharged between January 1, 2004, and December 31, 2006. We evaluated the performance of claims-only and claims-clinical regression models for 30-day mortality and readmission, and compared hospital rankings from both models. There were 25 766 patients from 308 hospitals in the mortality analysis, and 24 163 patients from 307 hospitals in the readmission analysis. The claims-clinical mortality model (area under the curve [AUC], 0.761; generalized R(2)=0.172) had better fit than the claims-only mortality model (AUC, 0.718; R(2)=0.113). The claims-only readmission model (AUC, 0.587; R(2)=0.025) and the claims-clinical readmission model (AUC, 0.599; R(2)=0.031) had similar performance. Among hospitals ranked as top or bottom performers by the claims-only mortality model, 12% were not ranked similarly by the claims-clinical model. For the claims-only readmission model, 3% of top or bottom performers were not ranked similarly by the claims-clinical model.


CONCLUSIONS
Adding clinical data to claims data for heart failure hospitalizations significantly improved prediction of mortality, and shifted mortality performance rankings for a substantial proportion of hospitals. Clinical data did not meaningfully improve the discrimination of the readmission model, and had little effect on performance rankings.
Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA. brad.hammill@duke.edu
Bradley G
BG
Hammill
Lesley H
LH
Curtis
Gregg C
GC
Fonarow
Paul A
PA
Heidenreich
Clyde W
CW
Yancy
Eric D
ED
Peterson
Adrian F
AF
Hernandez
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006333:Heart Failure / Q000401:mortality*; D006760:Hospitalization; D006801:Humans; D008297:Male; D006278:Medicare; D017063:Outcome Assessment, Health Care; D010359:Patient Readmission / Q000706:statistics & numerical data; D020379:Risk Adjustment; D014481:United States