UVA/riboflavin crosslinking as treatment for corneal melting.
OBJECTIVE
To demonstrate that UVA/riboflavin crosslinking (CXL) can stop corneal melting in therapy resistant infectious corneal ulceration.


METHODS
We will present a case report on a 70-year-old female patient referred for severe infectious ulcerative keratitis caused by Pseudomonas aeruginosa. After intensive treatment with fortified antibiotics, corneal melting developed. CXL was performed to avoid imminent corneal perforation.


RESULTS
The CXL treatment was successful: the corneal melting was stopped and the lesion cicatrized, thereby avoiding emergency keratoplasty.


CONCLUSIONS
This case report highlights that CXL may be a valuable addition to our therapeutic armamentarium in the treatment of corneal melts.
Department of Ophthalmology, Antwerp University Hospital. alsabay2000@msn.com
N
N
Al-Sabai
C
C
Koppen
M J
MJ
Tassignon
D000368:Aged; D003316:Corneal Diseases / Q000188:drug therapy* / Q000209:etiology; D003320:Corneal Ulcer / Q000150:complications / Q000382:microbiology*; D003432:Cross-Linking Reagents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012256:Riboflavin / Q000627:therapeutic use*
D003432:Cross-Linking Reagents; D012256:Riboflavin