Disseminated herpes simplex virus type 1 primary infection in a healthy individual.
BACKGROUND
Primary herpes simplex virus (HSV) infection usually involves one mucosal region.


OBJECTIVE
To describe an unusual disseminated HSV-1 infection involving two mucosal sites in a healthy man.


RESULTS
Primary HSV infection involved oral and genital mucosa and was associated with viremia, hepatitis and rash. Phylogenetic analysis of genital and oral viruses revealed that the patient was infected by a single HSV-1 strain.


CONCLUSIONS
Use of polymerase chain reaction detection techniques for HSV may identify viremic patients in the absence of obvious immunosuppression.
Research Center in Infectious Diseases, Centre Hospitalier Universitaire de Québec;
Guy
G
Boivin
Brigitte
B
Malette
Nathalie
N
Goyette