Hepatobiliary manifestations of critically ill and postoperative patients.
Liver dysfunction is common in both the critically ill and postoperative patient. Metabolic derangements secondary to sepsis, poor hepatic perfusion, total parenteral nutrition, in addition to hemodynamic and anesthetic-induced changes that occur during surgery, can cause liver damage ranging from small self-limited abnormalities in liver chemistries to acute liver failure. Early recognition, supportive care, and effective treatment of the underlying disease process are crucial steps in managing liver disease in a critically ill patient.
Center for Liver Disease, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 7120, Chicago, IL 60637, USA.
Andrew
A
Aronsohn
Donald
D
Jensen
D001660:Biliary Tract Diseases / Q000209:etiology* / Q000503:physiopathology; D003422:Critical Care / Q000379:methods; D016638:Critical Illness; D006801:Humans; D008107:Liver Diseases / Q000209:etiology* / Q000503:physiopathology; D011184:Postoperative Period