Platinum(II)-triarylpyridines complexes with electropositive pendants as efficient G-quadruplex binders.
Herein we reported three new platinum(ii)-triarylpyridines complexes with peralkylated ammonium pendants that strongly stabilize G-quadruplex DNA.
MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
Jin-Tao
JT
Wang
Yi
Y
Li
Jia-Heng
JH
Tan
Liang-Nian
LN
Ji
Zong-Wan
ZW
Mao
D002942:Circular Dichroism; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D054856:G-Quadruplexes; D006801:Humans; D010984:Platinum / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D016615:Telomere / Q000737:chemistry; D044366:Transition Temperature
D056831:Coordination Complexes; D011725:Pyridines; D000644:Quaternary Ammonium Compounds; D010984:Platinum