[Role of endogenous intoxication in development of involutive and pathologic processes in patients of elderly and senile age with ischemic heart disease].
Blood toxicity and biochemical values were studied in 135 patients of different age with ischemic heart disease. Researches were carried out by means of bio-test method on "Cito-expert" apparatus. Blood toxicity was diagnosed in 85% patients of average age, in 87% patients of elderly age and in 95% patients of senile age with ischemic heart disease, which indicates endogenous intoxication. The study revealed correlation between age and blood toxicity (R=0,22; t=2,18; p<0,05). The increase of glucose, urea and lactate dehydrogenase content in blood was accompanied by growth of blood toxicity. Age-related raising of intoxication didn't have any relations with increasing of glucose, urea and lactate dehydrogenase content in blood, because there was no difference between concentration of these metabolites in patients of different age. The correlation between age and blood toxicity demonstrates pathogenetic role of endogenous intoxication in the development of involutive and pathologic process in elderly and senile patients with ischemic heart disease and confirms the necessity to stop it.
A V
AV
Makhneva
L P
LP
Sviridkina
S G
SG
Toporova
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood / Q000378:metabolism* / Q000473:pathology; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D017202:Myocardial Ischemia / Q000097:blood / Q000378:metabolism* / Q000473:pathology; D044967:Serum / Q000737:chemistry*; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D014508:Urea; D007770:L-Lactate Dehydrogenase