Lymphadenopathy and systemic lupus erythematosus.
Lymphadenopathy is a benign finding in systemic lupus erythematosus (SLE), commonly seen in young patients with cutaneous involvement and constitutional symptoms, with good response to corticosteroids. Reactive follicular hyperplasia is the most frequent finding in biopsies. We report the case of a patient with recurrent episodes of lymphadenopathy associated with hepatosplenomegaly, fever, and weight loss since the age of 13 years. The patient also developed arthritis, hypertension, proteinuria, cardiomyopathy, and peripheral neuropathy. His condition was investigated extensively without diagnostic clarification; he was treated, empirically, for tuberculosis. The patient received a diagnosis of SLE only five years after the original presentation and received the specific treatment. Early diagnosis in those cases is difficult because laboratory exams may not show the presence of auto-antibodies and low complement levels.
Serviço de Reumatologia, HC, FMUSP.
Nilton Salles Rosa
NS
Neto
Karina Rossi
KR
Bonfiglioli
Fernanda Manente
FM
Milanez
Patrícia Andrade
PA
de Macêdo
Maurício
M
Levy-Neto
D000293:Adolescent; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008206:Lymphatic Diseases / Q000209:etiology*; D008297:Male