Enzymatic characteristics of creatine kinase system under conditions of cerebral circulatory disorders.
Changes in the catalytic properties of cytoplasmic and mitochondrial creatine kinase were studied at various periods of cerebral circulatory disorders. Cerebral ischemia was accompanied by activation of free radical processes, changes in the dimer/octamer ratio for mitochondrial creatine kinase, and appearance of new catalytic properties of isoenzymes.
Nizhny Novgorod State Medical Academy, Ministry of Health Care and Social Development of the Russian Federation, Russia. prazina@yandex.ru
E I
EI
Yerlykina
T F
TF
Sergeeva
D000818:Animals; D021461:Animals, Outbred Strains; D002545:Brain Ischemia / Q000201:enzymology*; D002384:Catalysis; D003402:Creatine Kinase / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D019281:Dimerization; D007527:Isoenzymes / Q000378:metabolism; D008163:Luminescent Measurements; D008928:Mitochondria / Q000378:metabolism; D051381:Rats; D013053:Spectrophotometry
D007527:Isoenzymes; D003402:Creatine Kinase