False-positive amplified Mycobacterium tuberculosis direct tests in skin specimens of leprosy.
The amplified Mycobacterium tuberculosis (M tuberculosis) direct test (MTD) is reported to be a highly sensitive (92.6%) and specific (100%) test for the detection of M tuberculosis. We report two cases of human leprosy in which false-positive amplified MTD testing on skin biopsies led to initial misdiagnoses of cutaneous M tuberculosis.
Department of Dermatology, University of Florida, Gainesville, FL, USA.
Thomas S
TS
Breza
James M
JM
Magill
Na'im K
NK
Fanaian
Francisco A
FA
Ramos-Caro
D000368:Aged; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D007918:Leprosy / Q000175:diagnosis* / Q000382:microbiology; D008297:Male; D009166:Mycobacterium leprae / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D014374:Tuberculin Test / Q000379:methods*; D014382:Tuberculosis, Cutaneous / Q000175:diagnosis*; D055815:Young Adult