Antioxidant and antityrosinase activity of mulberry (Morus alba L.) twigs and root bark.
The antioxidant and antityrosinase activities of the ethanolic extract of mulberry twigs (EEMT) were investigated. The results showed that EEMT exhibited radical scavenging and reducing activity, as well as ferrous ion-chelating activity. In addition, EEMT also protected phospholipids against free radicals, indicating that EEMT could protect biomolecules from oxidative damage. Meanwhile, in the range of 0-60 μg/ml, the tyrosinase inhibitory activity of EEMT increased with increase in sample concentration, and was superior to that of the ethanolic extract of mulberry root bark (EEMR). High-performance liquid chromatography (HPLC) analysis was employed to determine the phenolic components, revealing that maclurin, rutin, isoquercitrin, resveratrol, and morin were present in EEMT. Acting as an antioxidant and a tyrosinase inhibitor, these bioactive constituents could contribute to the protective effects of EEMT. Overall, the results showed that EEMT might serve as a natural antioxidant and tyrosinase inhibitor.
Department of Food Science and Technology, Chia Nan University of Pharmacy and Science, 60 Erh-Jen Rd, Sec 1, Tainan, Taiwan, ROC.
Lee-Wen
LW
Chang
Lih-Jeng
LJ
Juang
Bor-Sen
BS
Wang
Mei-Ying
MY
Wang
Huo-Mu
HM
Tai
Wei-Jing
WJ
Hung
Yun-Ju
YJ
Chen
Ming-Hsing
MH
Huang
D000975:Antioxidants / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors*; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*
D000975:Antioxidants; D004791:Enzyme Inhibitors; D010936:Plant Extracts; D014442:Monophenol Monooxygenase