Bacteraemia and breast abscess: unusual extra-intestinal manifestations of Clostridium difficile infection.
Extra-intestinal manifestations of Clostridium difficile infection are uncommon. Most cases are associated with gastrointestinal disease and often occur as a mixed infection with other gut flora. We report a case of breast abscess following monomicrobial C. difficile bacteraemia in a female with background chronic hepatitis C infection and alcoholic liver disease. No evidence of colitis was found. Our case shows that C. difficile is indeed capable of spreading from the gastrointestinal tract.
Infectious Diseases Unit, University Hospital of Wales, Heath Park, Cardiff CF14 6PQ, UK.
Oyewole
O
Durojaiye
Department of Medical Microbiology, Royal Gwent Hospital, Cardiff Road, Newport NP20 2UB, UK.
Soma
S
Gaur
Department of Medical Microbiology, University Hospital of Wales, Heath Park, Cardiff CF14 6PQ, UK.
Layth
L
Alsaffar
D000038:Abscess / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D001940:Breast / Q000382:microbiology / Q000473:pathology; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000150:complications; D008413:Mastitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D016217:Ultrasonography, Mammary