Phytotoxic clerodane diterpenes from Salvia miniata Fernald (Lamiaceae).
Our ongoing research to identify natural growth inhibitors with diterpene and triterpene skeletons exuding from the surface of the aerial parts of Salvia species led us to study Salvia miniata Fernald. Ten clerodane diterpenoids were found, along with three known diterpenes. Most of the isolated compounds from S. miniata inhibited the germination of Papaver rhoeas L. and Avena sativa L. in Petri dish experiments. Parallel results have been obtained in experiments carried out to evaluate the subsequent growth of the seedlings of the target species in the presence of the tested compounds.
Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, Università di Genova, Genova, Italy. bisio@dictfa.unige.it
Angela
A
Bisio
Gianluca
G
Damonte
Daniele
D
Fraternale
Emanuela
E
Giacomelli
Annalisa
A
Salis
Giovanni
G
Romussi
Sergio
S
Cafaggi
Donata
D
Ricci
Nunziatina
N
De Tommasi
D018554:Avena / Q000187:drug effects; D002734:Chlorophyll / Q000032:analysis; D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018525:Germination / Q000187:drug effects; D007558:Italy; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010207:Papaver / Q000187:drug effects; D027544:Salvia / Q000737:chemistry*
D045785:Diterpenes, Clerodane; D002734:Chlorophyll