Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications.
In recent years, nanomaterials have captured the attention of scientists from a wide spectrum of domains. With their unique properties, nanomaterials offer great promise for numerous applications, ranging from catalysis to energy harvesting and information technology. Functionalized with the desired biomolecules, nanomaterials can also be utilized for many biomedical applications. This paper summarizes recent achievements in the use of aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications. First, we discuss the features and properties of aptamers and then illustrate the use of aptamer-conjugated nanomaterials as sensing platforms and delivery vehicles, emphasizing how such integration can result in enhanced sensitivity and selectivity.
Department of Chemistry, Shands Cancer Center, University of Florida Genetics Institute, Gainesville, FL 32611-7200, USA.
Tao
T
Chen
Mohammed Ibrahim
MI
Shukoor
Yan
Y
Chen
Quan
Q
Yuan
Zhi
Z
Zhu
Zilong
Z
Zhao
Basri
B
Gulbakan
Weihong
W
Tan
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D006046:Gold / Q000737:chemistry; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D037742:Nanotubes, Carbon; D012822:Silicon Dioxide / Q000737:chemistry
D052157:Aptamers, Nucleotide; D037742:Nanotubes, Carbon; D006046:Gold; D012822:Silicon Dioxide