Treatment of post-burn leucoderma with non-cultured melanocyte-keratinocyte transplantation (MKTP).
BACKGROUND
Deep burns often result in hypo-pigmentation, referred to as leucoderma which has a similar psychosocial impact on the patients as that of vitiligo. Several tissue grafting methods have been reported to treat post-burn leucoderma.


METHODS
A simple method consisting of harvesting a donor skin sample, preparation of an epidermal cell suspension and the transplantation of the cell suspension on to a dermabraded recipient area, was performed in a clean procedure room. No special laboratory set-up was used for the cell separation procedure. Patients were treated with 18 sessions of excimer laser starting 1 month post-operatively, to hasten the repigmentation.


METHODS
Of the 10 patients treated with MKTP, 3 were lost to follow-up. The remaining 7 patients showed repigmentation ranging from 90% to 100% with good color matching.


CONCLUSIONS
MKTP is an effective method to treat post-burn leucoderma. No special precautions are required to treat any anatomical site or uneven scarred surface.
National Center for Vitiligo & Psoriasis, Riyadh, Saudi Arabia. mulekar@gmail.com
Sanjeev V
SV
Mulekar
Ahmed Al
AA
Issa
Abdullah Al
AA
Eisa
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D002056:Burns / Q000150:complications* / Q000473:pathology; D017690:Cell Transplantation / Q000379:methods*; D002648:Child; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000601:surgery*; D015603:Keratinocytes / Q000637:transplantation*; D008297:Male; D008544:Melanocytes / Q000637:transplantation*; D008875:Middle Aged; D055815:Young Adult