And four equals one: presenilin takes the gamma-secretase role by itself.
Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA.
Christian B
CB
Lessard
Steven L
SL
Wagner
Edward H
EH
Koo
D000544:Alzheimer Disease; D053829:Amyloid Precursor Protein Secretases / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D004789:Enzyme Activation; D006801:Humans; D009154:Mutation; D053764:Presenilin-1 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D016564:Amyloid beta-Protein Precursor; D053764:Presenilin-1; D053829:Amyloid Precursor Protein Secretases