Uncovering new properties of imidazolium salts: Cl- transport and supramolecular regulation of their transmembrane activity.
We report the Cl(-) transport activity for three imidazolium-based transporters. We present significant findings regarding the use of α-cyclodextrin and cucurbit[7]uril macrocycles to form inclusion complexes with these salts and to inhibit their membrane activity.
Department of Chemistry, Université de Montréal, 2900 Edouard Montpetit CP 6128 Succursalle Centre-ville, Montréal, Québec, Canada.
Claude-Rosny
CR
Elie
Nadim
N
Noujeim
Christophe
C
Pardin
Andreea R
AR
Schmitzer
D000838:Anions / Q000737:chemistry / Q000378:metabolism; D001692:Biological Transport; D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000378:metabolism; D002021:Buffers; D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism*; D002463:Cell Membrane Permeability; D002712:Chlorides / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry / Q000378:metabolism; D048288:Imidazolines / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D012492:Salts / Q000737:chemistry* / Q000378:metabolism; D012996:Solutions / Q000737:chemistry; D047391:alpha-Cyclodextrins / Q000737:chemistry / Q000378:metabolism; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
D000838:Anions; D001952:Bridged-Ring Compounds; D002021:Buffers; D002712:Chlorides; D007093:Imidazoles; D048288:Imidazolines; D012492:Salts; D012996:Solutions; D047391:alpha-Cyclodextrins; C456276:cucurbit(7)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils; C032613:alpha-cyclodextrin