Genetic relatedness of Trichomonas vaginalis reference and clinical isolates.
We have determined the metronidazole susceptibility status of 20 Trichomonas vaginalis isolates from American Type Culture Collection (ATCC) and assessed the level of genetic relatedness in these isolates using 32 additional T. vaginalis clinical isolates for comparison. These ATCC isolates are commonly used as reference strains in T. vaginalis research and this information provides a rational basis for selection of reference strains for use in comparative studies of T. vaginalis phenotypic and clinical characteristics.
Department of Microbiology, Division of Infectious Diseases, University of Mississippi Medical Center, Jackson, Mississippi 39216-4505, USA. dcornelius@umc.edu
Denise C
DC
Cornelius
Leandro
L
Mena
William B
WB
Lushbaugh
John C
JC
Meade
D000981:Antiprotozoal Agents / Q000494:pharmacology; D004351:Drug Resistance / Q000235:genetics; D014644:Genetic Variation; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010802:Phylogeny; D014245:Trichomonas Infections / Q000469:parasitology; D014246:Trichomonas vaginalis / Q000187:drug effects / Q000235:genetics*
D000981:Antiprotozoal Agents; D008795:Metronidazole