Sensing magnetic flux density of artificial neurons with a MEMS device.
We describe a simple procedure to characterize a magnetic field sensor based on microelectromechanical systems (MEMS) technology, which exploits the Lorentz force principle. This sensor is designed to detect, in future applications, the spiking activity of neurons or muscle cells. This procedure is based on the well-known capability that a magnetic MEMS device can be used to sense a small magnetic flux density. In this work, an electronic neuron (FitzHugh-Nagumo) is used to generate controlled spike-like magnetic fields. We show that the magnetic flux density generated by the hardware of this neuron can be detected with a new MEMS magnetic field sensor. This microdevice has a compact resonant structure (700 × 600 × 5 μm) integrated by an array of silicon beams and p-type piezoresistive sensing elements, which need an easy fabrication process. The proposed microsensor has a resolution of 80 nT, a sensitivity of 1.2 V.T(-1), a resonant frequency of 13.87 kHz, low power consumption (2.05 mW), quality factor of 93 at atmospheric pressure, and requires a simple signal processing circuit. The importance of our study is twofold. First, because the artificial neuron can generate well-controlled magnetic flux density, we suggest it could be used to analyze the resolution and performance of different magnetic field sensors intended for neurobiological applications. Second, the introduced MEMS magnetic field sensor may be used as a prototype to develop new high-resolution biomedical microdevices to sense magnetic fields from cardiac tissue, nerves, spinal cord, or the brain.
Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, 14 Sur 6301, Col. San Manuel, Puebla, Pue., Mexico.
Jesus A
JA
Tapia
Agustin L
AL
Herrera-May
Pedro J
PJ
García-Ramírez
Jaime
J
Martinez-Castillo
Eduard
E
Figueras
Amira
A
Flores
Elías
E
Manjarrez
D058045:Artificial Cells / Q000166:cytology*; D004560:Electricity; D055590:Electromagnetic Phenomena; D004867:Equipment Design; D008280:Magnetics / Q000295:instrumentation*; D055595:Mechanical Phenomena; D055616:Microtechnology / Q000295:instrumentation*; D009474:Neurons / Q000166:cytology*