Fluorescent strip sensor for rapid determination of toxins.
Here, we report a simple fluorescent strip sensor based on aptamer-quantum dots technology that can meet toxin monitoring demands using ochratoxin A (OTA) as a model toxin. The limit of the detection (LOD) for the fluorescent strip was 1.9 ng mL(-1), while the time needed for the detection is only 10 min; this conforms to the standards of World Health Organization (WHO) or better. Overall functional parameters are also better than the analogous characteristics of gold nanoparticle strips. High selectivity was maintained as well, making them suitable for the samples with complex solution composition.
School of Food Science & Technology, State Key Lab of Food Science & Technology, Jiangnan University, Wuxi, 214122, PRC.
Libing
L
Wang
Wei
W
Chen
Wenwei
W
Ma
Liqinag
L
Liu
Wei
W
Ma
Yuan
Y
Zhao
Yingyue
Y
Zhu
Liguang
L
Xu
Hua
H
Kuang
Chuanlai
C
Xu
D052157:Aptamers, Nucleotide / Q000138:chemical synthesis / Q000737:chemistry*; D015374:Biosensing Techniques; D002273:Carcinogens / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D053758:Nanoparticles; D009793:Ochratoxins / Q000032:analysis*; D045663:Quantum Dots; D011934:Reagent Strips; D013050:Spectrometry, Fluorescence
D052157:Aptamers, Nucleotide; D002273:Carcinogens; D009793:Ochratoxins; D011934:Reagent Strips; C025589:ochratoxin A; D006046:Gold