Glycomics hits the big time.
Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.
Department of Biological Chemistry, Johns Hopkins University, Baltimore, MD 21205-2185, USA. gwhart@jhmi.edu
Gerald W
GW
Hart
Ronald J
RJ
Copeland
D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis; D006017:Glycolipids / Q000032:analysis; D054794:Glycomics; D006031:Glycosylation; D016695:Glycosyltransferases / Q000235:genetics / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis; D011134:Polysaccharides / Q000032:analysis / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D011509:Proteoglycans / Q000032:analysis
D014408:Biomarkers, Tumor; D006017:Glycolipids; D011134:Polysaccharides; D011509:Proteoglycans; D016695:Glycosyltransferases