Conjunctival lymphoma in a child.
OBJECTIVE
To report a rare case of large conjunctival B-cell lymphoma in a child.


METHODS
A 13-year-old girl was initially diagnosed with a right lower eyelid chalazion. After 3 weeks during which the mass was growing, she was referred for treatment to our department. Because of the unusual appearance of the mass, an excisional biopsy was performed.


RESULTS
Pathological findings were consistent with those of a large B-cell lymphoma. CD20 and Ki67 staining were positive, and polymerase chain reaction analysis showed monoclonality of B cells.


CONCLUSIONS
Although conjunctival lymphoma is a very rare entity in children, it should be included in the differential diagnosis of an eyelid or conjunctival mass.
Department of Ophthalmology, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. mwaisbourd@hotmail.com
Michael
M
Waisbourd
Igal
I
Leibovitch
Dror
D
Sayar
Ronit
R
Elhasid
D000293:Adolescent; D018951:Antigens, CD20 / Q000378:metabolism; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor; D003230:Conjunctival Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004273:DNA, Neoplasm / Q000032:analysis; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D016133:Polymerase Chain Reaction; D011241:Prednisone / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D019394:Ki-67 Antigen; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone