An update on Cryptococcus among HIV-infected patients.
Cryptococcus remains an important opportunistic infection in HIV patients despite considerable declines in prevalence during the highly active antiretroviral therapy era. This is particularly apparent in sub-Saharan Africa, where Cryptococcus continues to cause significant mortality and morbidity. This review discusses the microbiology, epidemiology, pathogenesis and clinical presentation of cryptococcal infections in HIV patients. Additionally, a detailed approach to the management of cryptococcosis is provided.
Infectious Disease Clinic, Naval Medical Center San Diego, San Diego, CA 92134–1005, USA. tyler.warkentien@med.navy.mil
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D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000473:pathology; D017954:Africa South of the Sahara; D003453:Cryptococcosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000473:pathology; D003454:Cryptococcus / Q000302:isolation & purification; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015995:Prevalence