Palladium-catalyzed direct and regioselective C-H bond functionalization/oxidative acetoxylation of indoles.
The first general examples of palladium-catalyzed direct and selective oxidative C3-acetoxylation of indoles are presented. The mild reaction conditions (70 °C and with weak base, KOAc) in this indole C-H-acetoxylation are notable.
State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Pui Ying
PY
Choy
Chak Po
CP
Lau
Fuk Yee
FY
Kwong
D000107:Acetylation; D001593:Benzyl Compounds / Q000737:chemistry*; D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
D001593:Benzyl Compounds; D003432:Cross-Linking Reagents; D007211:Indoles; D010165:Palladium