Two new flavonoid glycosides from the whole herbs of Hyssopus officinalis.
Two new flavonoid glycosides, quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside (1) and quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside 3'-O-β-D-glucopyranoside (2), together with nine known flavonoids were isolated from the whole herbs of Hyssopus officinalis L. cultivated in Xinjiang Uygur Autonomous Region of China. All structures were characterized by the spectroscopic methods including UV, IR, ESI-MS, 1D, and 2D NMR. Their potent free radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical was evaluated.
State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Nan
N
Wang
Xiu-Wei
XW
Yang
D000465:Algorithms; D001713:Biphenyl Compounds / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019686:Lamiaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism
D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; C554744:quercetin 7-O-beta-D-apiofuranosyl-(1-2)-beta-D-xylopyranoside; C554745:quercetin 7-O-beta-D-apiofuranosyl-(1-2)-beta-D-xylopyranoside 3'-O-beta-D-glucopyranoside; D011794:Quercetin; C004931:1,1-diphenyl-2-picrylhydrazyl