Coexistence of Hashimoto's thyroiditis with papillary thyroid carcinoma. A retrospective study.
OBJECTIVE
The association between Hashimoto's thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains controversial in medical bibliography. The main objective of our study was to determine the prevalence of PTC and HT coexistence in histopathologic material of thyroidectomized patients.


METHODS
In a retrospective study, the clinicohistopathologic data of 140 patients (19 males/121 females), who underwent a total or near total thyroidectomy for any thyroid pathology from January 2005 to December 2009 at the Naval Hospital of Crete, were analysed. The mean age of the patients was 52 years (range 16-74).


RESULTS
HT was detected in 42 (30%) and PTC in 32 (22.9%) specimens. Coexistence of HT with PTC was present in 12 (8.6%) specimens. Among 32 specimens with PTC, the prevalence of HT was 37.5%. Among 42 specimens with HT, the prevalence of PTC was 28.6%. There was no statistically significant difference between the presence of PTC and HT in histopathologic material.


CONCLUSIONS
The prevalence of PTC and HT coexistence in histopathologic material of 140 thyroidectomized patients was 8.6%, whereas the difference between PTC and HT was not statistically significant.
Department of Internal Medicine, Naval Hospital of Crete, Greece. emazokopakis@yahoo.gr
Elias E
EE
Mazokopakis
Anastasios A
AA
Tzortzinis
Elpida I
EI
Dalieraki-Ott
Athanasios N
AN
Tsartsalis
Periklis K
PK
Syros
Christos M
CM
Karefilakis
Maria G
MG
Papadomanolaki
Ioannis K
IK
Starakis
D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000150:complications* / Q000473:pathology; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D013961:Thyroid Gland / Q000473:pathology / Q000601:surgery; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology; D013965:Thyroidectomy