Proteomics in ocular fluids.
The focus of this article is to review recent techniques in proteomic analysis of ocular fluids. These fluids include tears, aqueous humor, and vitreous, they will also be compared to serum analysis. Furthermore, we attempt to summarize some disease correlated biomarkers in ocular fluids that were discovered through different proteomic techniques in eye diseases like dry eye, glaucoma, age-related macular degeneration, uveitis, or diabetic retinopathy. This review is trying to point out the importance of these biomarkers for clinical applications.
Experimental Ophthalmology, Department of Ophthalmology, Johannes Gutenberg University, Mainz, Germany. grus@eye-research.org.
Franz H
FH
Grus
Stephanie C
SC
Joachim
Norbert
N
Pfeiffer