Multifunctional divalent vancomycin: the fluorescent imaging and photodynamic antimicrobial properties for drug resistant bacteria.
A simple and specific divalent vancomycin-porphyrin has been developed. This divalent vancomycin-porphyrin conjugate indicates promising properties in fluorescent imaging and photodynamic inactivation of vancomycin-sensitive and vancomycin-resistant enterococci (VRE) bacterial strains.
Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore, 637371. Bengang@ntu.edu.sg
Bengang
B
Xing
Tingting
T
Jiang
Wuguo
W
Bi
Yanmei
Y
Yang
Lihua
L
Li
Manlun
M
Ma
Chi-Kwong
CK
Chang
Bing
B
Xu
Edwin Kok Lee
EK
Yeow
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005453:Fluorescence; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010778:Photochemotherapy; D013290:Streptococcal Infections / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D013291:Streptococcus / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology*; D020713:Vancomycin Resistance / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D014640:Vancomycin