Accuracy of diagnoses delivered by an automated hand-held nerve conduction device in comparison to standard electrophysiological testing in patients with unilateral leg symptoms.
BACKGROUND
Automated hand-held nerve conduction study (NCS) devices are being marketed for use in the diagnosis of lumbosacral radiculopathy (LSR). In this study we compared the specificity and sensitivity of a hand-held NCS device for the detection of LSR with standard electrodiagnostic study (EDX).


METHODS
Fifty patients referred to a tertiary referral electromyography (EMG) laboratory for testing of predominantly unilateral leg symptoms (weakness, sensory complaints, and/or pain) were included in the investigation. Twenty-five normal "control" subjects were later recruited to calculate the specificity of the automated protocol. All patients underwent standard EDX and automated testing.


RESULTS
Raw NCS data were comparable for both techniques; however, computer-generated interpretations delivered by the automated device showed high sensitivity with low specificity (i.e., many false positives) in both symptomatic patients and normal controls.


CONCLUSIONS
The automated device accurately recorded raw data, but the interpretations provided were overly sensitive and lacked the specificity necessary for a screening or diagnostic examination.
Department of Physical Medicine and Rehabilitation, Mayo Clinic and Foundation, 200 First Street SW, Rochester, Minnesota 55902, USA.
Kevin
K
Schmidt
Nataly Montes
NM
Chinea
Eric J
EJ
Sorenson
Jeffrey A
JA
Strommen
Andrea J
AJ
Boon
D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D004568:Electrodiagnosis / Q000295:instrumentation* / Q000379:methods; D004582:Electronics, Medical / Q000592:standards / Q000639:trends*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D010525:Peripheral Nerves / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D011237:Predictive Value of Tests; D055815:Young Adult