[BK-virus-associated Nephropathy].
The infection by the BK Polyomavirus (BKV) is an emerging problem in kidney transplants that contributes to a chronic loss of kidney grafts, and in which immunosuppression plays a decisive role. Understanding its risk factors and strictly monitoring urine and serological markers of the infection could mitigate the undesirable effects of this disease. In this review, we investigate the clinical and epidemiological aspects of the BKV infection, as well as go over the available prophylactic and treatment methods currently available for controlling the infection in kidney transplant patients that receive modern immunosuppression.
Servicio de Nefrología, Hospital Carlos Haya, Málaga.
D
D
Burgos
C
C
Jironda
M
M
Martín
M
M
González-Molina
D
D
Hernández
D000998:Antiviral Agents / Q000627:therapeutic use; D001739:BK Virus / Q000302:isolation & purification / Q000472:pathogenicity*; D006085:Graft Survival; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002479:Inclusion Bodies / Q000648:ultrastructure / Q000821:virology; D016030:Kidney Transplantation; D009393:Nephritis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology / Q000517:prevention & control / Q000821:virology*; D027601:Polyomavirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology / Q000473:pathology / Q000517:prevention & control / Q000821:virology*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology / Q000517:prevention & control / Q000821:virology*; D011300:Preoperative Care; D014556:Urine / Q000821:virology; D014775:Virus Activation
D000998:Antiviral Agents; D007166:Immunosuppressive Agents