Clinical inquiries. Which patients benefit from lowering LDL to <100 mg/dL?
Patients who have coronary heart disease (CHD) or are at high risk for CHD should aim for a low-density lipoprotein (LDL) target of <100 mg/dL. An LDL target of <70 mg/dL is an option for very-high-risk patients (strength of recommendation [SOR]: C, expert opinion). The evidence also indicates that high-risk patients benefit from a statin-preferably in high doses-regardless of their baseline LDL or degree of LDL reduction with treatment (SOR: A, a large randomized controlled trial [RCT] and meta-analyses).
University of Wisconsin, School of Medicine and Public Health, Madison, WI, USA.
Ann
A
Evensen
Marguerite
M
Elliott
Christopher
C
Hooper-Lane
D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D008078:Cholesterol, LDL / Q000097:blood*; D003327:Coronary Disease / Q000097:blood* / Q000175:diagnosis / Q000517:prevention & control*; D006801:Humans; D018579:Patient Selection; D012307:Risk Factors
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL