Oral methylphenidate normalizes cingulate activity and decreases impulsivity in cocaine addiction during an emotionally salient cognitive task.
Department of Medical Research, Center for Translational Neuroimaging, Brookhaven National Laboratory, Upton, NY, USA. rgoldstein@bnl.gov
Rita Z
RZ
Goldstein
Nora D
ND
Volkow
D000284:Administration, Oral; D000328:Adult; D001931:Brain Mapping / Q000379:methods; D019970:Cocaine-Related Disorders / Q000188:drug therapy* / Q000378:metabolism / Q000523:psychology; D003071:Cognition / Q000187:drug effects* / Q000502:physiology; D018765:Dopamine Uptake Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D004644:Emotions / Q000187:drug effects / Q000502:physiology; D005260:Female; D006179:Gyrus Cinguli / Q000033:anatomy & histology / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D007175:Impulsive Behavior / Q000188:drug therapy* / Q000378:metabolism / Q000523:psychology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008774:Methylphenidate / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards; D013647:Task Performance and Analysis; D016896:Treatment Outcome
D018765:Dopamine Uptake Inhibitors; D008774:Methylphenidate