Glucose levels and hemodynamic changes in patients submitted to routine dental treatment with and without local anesthesia.
OBJECTIVE
The aim of this study was to (1) observe the extent to which hemodynamic and glucose measurements change in patients submitted to a dental procedure with and without a local anesthetic and a vasoconstrictor (LAVA; 2% mepivacaine with adrenaline 1100,000) and (2) correlate those parameters with the patients' anxiety levels.


METHODS
This was an unblinded, random, prospective, and observational study with paired groups. Patients were evaluated during two different consultations during which they either did or did not receive a local anesthetic/vasoconstrictor.


RESULTS
Thirty-seven patients ranging in age from 18 to 45 years (mean 30.4 ± 5.5 years) were evaluated. Hemodynamic parameters, including systolic blood pressure, diastolic blood pressure, heart rate, and glucose levels, did not change significantly in healthy patients, regardless of whether a LAVA was administered during the dental treatment.


CONCLUSIONS
The patients' anxiety statuses neither varied significantly nor showed any correlation with the studied hemodynamic parameters and glucose levels, regardless of whether local anesthetics were used.
Faculdade de Odontologia, Oral and Maxillofacial Surgery (FUNOESC), Joaçaba, Santa Catarina, Brazil. mbortoluzzi@gmail.com
Marcelo Carlos
MC
Bortoluzzi
Rafael
R
Manfro
Anderson
A
Nardi
D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000772:Anesthesia, Local / Q000009:adverse effects*; D001786:Blood Glucose / Q000032:analysis*; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D016854:Dental Anxiety / Q000378:metabolism*; D004837:Epinephrine / Q000009:adverse effects; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D008619:Mepivacaine / Q000009:adverse effects; D008875:Middle Aged; D014662:Vasoconstrictor Agents / Q000009:adverse effects*; D055815:Young Adult
D001786:Blood Glucose; D014662:Vasoconstrictor Agents; D008619:Mepivacaine; D004837:Epinephrine