Primary Hodgkin lymphoma of the ileum.
Primary classical Hodgkin lymphomas of the gastrointestinal tract are rare lymphoproliferative neoplasms as against other well established mucosa-associated lymphoid tissue (MALT) lymphomas. The primary nature of these cases is established based on chest radiograph, computed axial tomography, positron emission tomography, peripheral blood and bone marrow biopsy examination. Here, we report a 79-year-old male patient, who presented to the emergency department with complaints of abdominal discomfort on right side and low grade fever. An ultrasonogram was performed which suggested of an intestinal perforation. An emergency laporotomy was done with resection of the ileal segment. The histomorphology of the resected ileal segment revealed features of classical Hodgkin lymphoma which were confirmed by immunohistochemistry. Epstein Barr virus encoded RNA (EBER) via in-situ hybridization was positive and provided substantial evidence of EBV etiology.
Department of Histopathology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, Delhi 110085, India. jgandhi@gmail.com
Jatin S
JS
Gandhi
Anurag
A
Mehta
Anila
A
Sharma
Meenakshi
M
Kamboj
D000368:Aged; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007082:Ileum / Q000473:pathology*; D007150:Immunohistochemistry; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male