Uveitis in adult patients with rheumatic inflammatory autoimmune diseases at a tertiary-care hospital in Mexico City.
OBJECTIVE
Our aim is to describe the frequency of uveitis associated with rheumatic inflammatory autoimmune diseases (RIAD) in adult patients admitted to the Rheumatology Department at a tertiary-care hospital in Mexico City. We also describe the clinical features, seasonal distribution, treatment, and ocular complications associated with this disease.


METHODS
We reviewed 1332 charts of patients with RIAD and selected those that had a diagnosis of uveitis. We obtained the following data: age, sex, type of uveitis and relationship with diagnosis of RIAD, recurrences, seasonal distribution, treatment, and residual visual deficit.


RESULTS
We found 57 (4.27%) cases of uveitis in 1332 charts, including 38 men and 19 women (M:F ratio 2:1), aged 47 ± 16 years. Nongranulomatous acute anterior uveitis (NGAAU) comprised 90.52% of cases (52/57). In 64.91% of cases (37/57), uveitis preceded the diagnosis of RIAD by 12 ± 9 years, more frequently in winter (35.96%; p = NS). Uveitis was found in 40/93 patients with ankylosing spondylitis (AS), in 7/11 patients with relapsing polychondritis (RP), in 8/16 patients with Behçet's disease, in 1/16 patients with polyarteritis nodosa, and in 1/590 patients with rheumatoid arthritis (RA). Ninety-six percent of the patients were treated with steroids. Upon a mean followup of 60 days (range 7-4745 days), reduction of visual acuity (≤ 20/200) was associated with recurrence of uveitis in 3/7 cases with AS, in 4/8 cases with Behçet's disease, in 3/7 with RP, and in 1 case of uveitis and seronegative RA.


CONCLUSIONS
NGAAU frequently precedes RIAD and is found predominately in men, with a tendency to occur in winter.
Pregonero 161, Frac. Colina del Sur, CP 01430, México, DF, Mexico. fjjimenez19@yahoo.com
Francisco Javier
FJ
Jiménez-Balderas
Gema
G
Fernandez-Arrieta
Adolfo
A
Camargo-Coronel
Miguel Ángel
MÁ
Ake-Uc
Miguel Angel
MA
Vazquez-Zaragoza
Abraham
A
Zonana-Nacach
Luis Roberto
LR
Sánchez-González
Rita
R
Rios
Francisco
F
Martinez-Castro
D000293:Adolescent; D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D007249:Inflammation / Q000150:complications*; D008297:Male; D008800:Mexico; D008875:Middle Aged; D012216:Rheumatic Diseases / Q000150:complications*; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis