Recurrent aphasic status epilepticus after prolonged generalized tonic-clonic seizures versus a special feature of Todd's paralysis.
Postictal aphasia may be a feature of Todd's paralysis or the presentation of aphasic nonconvulsive status epilepticus (NCSE). We describe a 74-year-old woman with three episodes of aphasic status epilepticus after prolonged generalized tonic-clonic seizures. In the first episode, the NCSE was not definitively diagnosed, but an increase in the epileptic medication led to resolution of the epileptic activity within 2 weeks. During the second episode, NCSE was terminated within 7 days under intensified antiepileptic treatment. In the third episode, phenytoin treatment led to intoxication and resulted in further treatment on an intensive care unit. The patient required several months to recover from this episode. NCSE in the elderly is difficult to recognize, especially when it presents as a prolonged postictal deficit like aphasia. Once diagnosed it has to be treated carefully, because in the elderly, aggressive treatment strategies may be associated with a high risk of adverse events.
Klinik und Poliklinik für Neurologie, Universität Rostock, Rostock, Germany. Johannes.roesche@med.uni-rostock.de
J
J
Rösche
A
A
Schley
A
A
Schwesinger
A
A
Grossmann
H
H
Mach
R
R
Benecke
U
U
Walter
D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D001037:Aphasia / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D010243:Paralysis / Q000175:diagnosis*; D012640:Seizures / Q000175:diagnosis* / Q000188:drug therapy; D013226:Status Epilepticus / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
D000927:Anticonvulsants