Serial position effects in mild cognitive impairment.
Mild cognitive impairment (MCI) is often associated with the preclinical phase of Alzheimer's disease (AD). Special scoring of word-list recall data for serial position has been suggested to improve discrimination of normal aging from dementia. We examined serial position effects in word-list recall for MCI participants compared to Alzheimer patients and controls. Individuals with MCI, like Alzheimer patients, had a diminished primacy effect in recalling words from a list. No alternative scoring system was better than standard scoring of word-list recall in distinguishing MCI patients from controls. Retention weighted scoring improved the discrimination of MCI and AD groups.
Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland, OR 97239-3098, USA. howiesod@ohsu.edu
Diane B
DB
Howieson
Nora
N
Mattek
Adriana M
AM
Seeyle
Hiroko H
HH
Dodge
Dara
D
Wasserman
Tracy
T
Zitzelberger
Kaye
K
Jeffrey
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology; D003072:Cognition Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D009483:Neuropsychological Tests; D012372:ROC Curve; D012691:Serial Learning / Q000502:physiology*; D014706:Verbal Learning / Q000502:physiology