[Adherence and cognitive performance in schizophrenia].
BACKGROUND
It is known that many patients with schizophrenia show non-adherence with regard to antipsychotic medication. Furthermore, many studies indicate cognitive deficits in schizophrenic patients. In this review, we compare the results of studies examining the relationship of non-adherence and cognitive performance.


METHODS
Based on a systematic literature review, the impact of cognitive performance on the adherence behaviour of patients with schizophrenia was examined.


RESULTS
We found 18 studies analysing the impact of cognitive performance on adherence behaviour. Most studies indicated that patients with stronger cognitive impairments show lower adherence behaviour. Possible causal mechanisms are discussed.
Abteilung für Forschung, Qualitätssicherung und Dokumentation, Klinik für Psychiatrie und Psychotherapie Bethel, Bielefeld. alexa_spiekermann@gmx.de
A
A
Spiekermann
M
M
Schulz
J
J
Behrens
M
M
Driessen
E
E
Rahn
T
T
Beblo
D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003071:Cognition / Q000502:physiology*; D006801:Humans; D007406:Interview, Psychological; D008991:Monitoring, Physiologic; D010349:Patient Compliance; D011597:Psychomotor Performance / Q000502:physiology*; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D012651:Self Medication
D014150:Antipsychotic Agents