Malignant atrophic papulosis: a case report with severe visual and neurological impairment.
Malignant atrophic papulosis, or Degos' disease, is a severe systemic vasculopathy extremely rare in children. The skin, gastrointestinal tract, and central nervous system are most frequently affected. We report a 5-year-old girl with malignant atrophic papulosis who presented with widespread skin lesions from early infancy and severe visual and neurological impairment.
Department of Dermatology, Hospital Niño Jesús, Madrid, Spain.
Marta
M
Gutiérrez-Pascual
Angela
A
Hernández-Martín
Isabel
I
Colmenero
Juan José
JJ
García-Peñas
Miguel Angel
MA
López-Pino
Antonio
A
Torrelo
D002545:Brain Ischemia / Q000209:etiology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D056784:Leukoencephalopathies / Q000209:etiology*; D054853:Malignant Atrophic Papulosis / Q000150:complications* / Q000473:pathology*; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology; D014786:Vision Disorders / Q000209:etiology*