The role of postexercise measurements in the diagnosis of peripheral arterial disease in HIV-infected patients.
Peripheral arterial disease (PAD) is a marker of atherosclerosis, which is not well studied in the population with human immunodeficiency virus (HIV). We prospectively enrolled HIV-infected patients who had normal resting ankle-brachial index (rABI) readings. All participants performed either a treadmill walking test (TT) or pedal plantar flexion test (PFT). Patients were divided into 2 groups according to postexercise changes; PAD and No-PAD group. The 2 groups were compared with regard to established cardiovascular disease risk factors and other HIV infection parameters. Peripheral arterial disease was present in 30 (26.5%) of 113 consecutive HIV-infected patients included in the study. Mean age was 47 ± 10 years. The risk factors studied did not differ significantly among the 2 groups except for male gender, which was significantly associated with PAD (RR: 4.15; CI: 1.6 to 11.1: P < .0008). The prevalence of PAD, diagnosed by significant drop in postexercise ABI and ankle pressure in patients with HIV is high.
Department of Cardiology, St Michaels Medical Center, Seton Hall University, Newark, NJ, USA.
Ashraf Y
AY
Qaqa
Vincent A
VA
DeBari
A
A
Isbitan
N
N
Mohammad
R
R
Sison
Jihad
J
Slim
George
G
Perez
Fayez E
FE
Shamoon
D015444:Exercise; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D011446:Prospective Studies