Screening Donors for Rare Antigen Constellations.
SCREENING BLOOD DONORS FOR RARE ANTIGEN CONSTELLATIONS HAS BEEN IMPLEMENTED USING SIMPLE PCR METHODS: PCR with enzyme digestion has been used to type donor cohorts for Dombrock antigens, and PCR with sequence-specific priming to identify donors negative for antigens of high frequency. The advantages and disadvantages of the methods as well as their current state is discussed.
DRK-Blutspendedienst NSTOB, Zentralinstitut Springe, Germany.
Franz F
FF
Wagner