Sustaining N2-dependent growth in the presence of CO.
Low levels of carbon monoxide inhibit the N(2)-dependent growth of Rhodospirillum rubrum unless the ∼100-residue CowN protein is expressed. Expression requires the CO-responsive regulator RcoM and is maximal in cells grown in the presence of CO and a poor nitrogen source, consistent with the role of CowN in N(2) fixation.
Department of Bacteriology, University of Wisconsin—Madison, Madison, Wisconsin 53706, USA.groberts@bact.wisc.edu
Robert L
RL
Kerby
Gary P
GP
Roberts
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000096:biosynthesis; D002248:Carbon Monoxide / Q000378:metabolism*; D015870:Gene Expression; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism*; D009586:Nitrogen Fixation; D012247:Rhodospirillum rubrum / Q000254:growth & development* / Q000378:metabolism*; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000378:metabolism
D001426:Bacterial Proteins; D014157:Transcription Factors; D002248:Carbon Monoxide; D009584:Nitrogen