Clinical inquiries. Do intra-articular steroid injections affect glycemic control in patients with diabetes?
Yes, but the clinical importance is minimal. A single intra-articular steroid injection into the knee produces acute hyperglycemia for 2 or 3 days in patients with diabetes who otherwise have good glucose control (strength of recommendation [SOR]: B, small cohort studies). Intra-articular steroid injections into the shoulder may briefly raise postprandial (but not mean) glucose levels with larger and repeated doses (SOR: C, extrapolated from heterogeneous and mixed cohort studies).
Valley Family Medicine Residency, Renton, WA, USA.
Erin
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Kallock
Jon O
JO
Neher
Sarah
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Safranek
D001786:Blood Glucose / Q000187:drug effects*; D003920:Diabetes Mellitus / Q000097:blood*; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D007270:Injections, Intra-Articular; D010003:Osteoarthritis / Q000097:blood / Q000150:complications / Q000188:drug therapy*
D001786:Blood Glucose; D005938:Glucocorticoids