Two ring-A-aromatized bile acids from the marine sponge Sollasella moretonensis.
Two ring-A-aromatized bile acids, 1 and 2, were isolated from the sponge Sollasella moretonensis, collected from the seabed of northern Queensland. Structures were assigned on the basis of extensive 1D and 2D NMR studies, as well as analysis by HRESIMS. Compound 2 has previously been produced synthetically, though this marks its first isolation from a natural source.
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
Zhenyu
Z
Lu
Ryan M
RM
Van Wagoner
Mary Kay
MK
Harper
John N A
JN
Hooper
Chris M
CM
Ireland
D000818:Animals; D001647:Bile Acids and Salts / Q000737:chemistry / Q000302:isolation & purification*; D002770:Cholenes / Q000302:isolation & purification*; D009654:Norsteroids / Q000302:isolation & purification; D011161:Porifera / Q000737:chemistry*
D001647:Bile Acids and Salts; D002770:Cholenes; D009654:Norsteroids; C057440:3-hydroxy-19-nor-1,3,5(10)-cholatrien-24-oic acid