Mycobacterium tuberculosis infection of domesticated Asian elephants, Thailand.
Four Asian elephants were confirmed to be infected with Mycobacterium tuberculosis by bacterial culture, other diagnostic procedures, and sequencing of 16S-23S rDNA internal transcribed spacer region, 16S rRNA, and gyrase B gene sequences. Genotyping showed that the infectious agents originated from 4 sources in Thailand. To identify infections, a combination of diagnostic assays is essential.
National Elephant Institute, Forest Industry Organization, Lampang, Thailand.
Taweepoke
T
Angkawanish
Worawidh
W
Wajjwalku
Anucha
A
Sirimalaisuwan
Sittidet
S
Mahasawangkul
Thattawan
T
Kaewsakhorn
Kittikorn
K
Boonsri
Victor P M G
VP
Rutten
D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology*; D001426:Bacterial Proteins / Q000235:genetics; D027081:DNA Gyrase / Q000235:genetics; D021903:DNA, Ribosomal Spacer; D004606:Elephants / Q000382:microbiology*; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012329:RNA, Bacterial / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D012338:RNA, Ribosomal, 23S / Q000032:analysis*; D016415:Sequence Alignment; D013785:Thailand; D014376:Tuberculosis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*
D001426:Bacterial Proteins; D021903:DNA, Ribosomal Spacer; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S; D027081:DNA Gyrase