A case of small undifferentiated intramucosal gastric cancer with lymph node metastasis.
Early gastric cancer (EGC) has a favorable prognosis after surgical gastrectomy. For intramucosal EGC with little risk of lymph node metastasis, endoscopic mucosal resection (EMR) is an accepted treatment method. Herein we document a noteworthy case of small undifferentiated gastric cancer with nodal metastasis. A 60-year-old Japanese woman underwent gastrectomy with D2 lymph node dissection for the treatment of EGC in the lower gastric body. Histological examination revealed that signet-ring cell carcinoma was located in approximately one-third of the superficial portion of the mucosal layer, with a tumor size of 13 mm. No lymphatic invasion, venous invasion, or fibrosis was observed in the submucosal layer. This case had nodal metastasis and was finally diagnosed as stage IB (T1N1M0) according to the Japanese Classification of Gastric Carcinoma (JCGC). The patient is alive without recurrence 6 years after treatment.
Department of Internal Medicine, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
Junichirou
J
Nasu
Shinichiro
S
Hori
Akinori
A
Asagi
Tomohiro
T
Nishina
Yoshio
Y
Ikeda
Masahito
M
Tanimizu
Haruo
H
Iguchi
Kenjiro
K
Aogi
Akira
A
Kurita
Rieko
R
Nishimura
D018279:Carcinoma, Signet Ring Cell / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome