Effect of botulinum toxin type A injection on lower facial contouring evaluated using a three-dimensional laser scan.
OBJECTIVE
To use three-dimensional (3D) laser scanning to elucidate changes in the external facial contour before and after botulinum toxin type A (BoNT-A) injections.


METHODS
BoNT-A was injected into 15 volunteers as a treatment for lower facial contouring. A total of 25 U of BoNT-A was injected into each side of the masseter muscle bilaterally. On each side, it was injected into two points at the center of the lower third of the masseter muscle separated by 1 cm. The clinical effects of BoNT-A were evaluated by performing 3D laser scans before and 4, 8, 12, and 24 weeks after the injection.


RESULTS
The mean values of the volume and widths of the most prominent area at each time point differed significantly before and 4, 8, 12, and 24 weeks after the injection.


CONCLUSIONS
The volumes and widths of the most prominent areas of the lower face (masseter muscle) were significantly lower 4, 8, 12, and 24 weeks after injecting BoNT-A than before the injection. The mean values of the volume and widths of the most prominent area were 2,176.93 mm(3) and 2.39 mm less, respectively, 24 weeks after the injection than before.
Department of Oral Medicine, Yonsei University, Seoul, Korea. ysom@yuhs.ac
Woo Hyun
WH
Shim
Seung Hyun
SH
Yoon
Ju Hyun
JH
Park
Young-Chan
YC
Choi
Seong Taek
ST
Kim
D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005145:Face; D005260:Female; D006801:Humans; D006984:Hypertrophy; D021621:Imaging, Three-Dimensional; D007273:Injections, Intramuscular; D007834:Lasers; D008297:Male; D008406:Masseter Muscle / Q000187:drug effects* / Q000473:pathology; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D055815:Young Adult
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A