[Control of bone remodeling by nervous system. Regulation of bone metabolism by appetite regulating neuropeptides].
The traditional view of bone metabolism as a primarily endocrine activity has been expanded in recent years following the identification of nervous system controlling bone metabolism by leptin studies. Especially, hypothalamic appetite regulating-peptides, such as NPY, CART and NMU have been demonstrated to be bone-regulating neuropeptides. Recently, other neuropeptides, such as serotonin and oxytocin, are reported to be associated with bone metabolism.
Section of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, Keio Univeristy, Japan.
Toru
T
Fukuda
Shu
S
Takeda
D000818:Animals; D001069:Appetite Regulation; D001842:Bone and Bones / Q000378:metabolism*; D054439:Ghrelin / Q000502:physiology; D006801:Humans; D020738:Leptin / Q000502:physiology; D051379:Mice; D009419:Nerve Tissue Proteins / Q000502:physiology; D009478:Neuropeptide Y / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology*; D010121:Oxytocin / Q000502:physiology; D012701:Serotonin / Q000502:physiology; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein
D054439:Ghrelin; D020738:Leptin; D009419:Nerve Tissue Proteins; D009478:Neuropeptide Y; D009479:Neuropeptides; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein; C056900:neuromedin U; D012701:Serotonin; D010121:Oxytocin