Determination of the effects of genistein on the longevity of Drosophila melanogaster meigen (Diptera; Drosophilidae).
In this study, the effects of genistein on the longevity of Drosophila melanogaster were investigated. The effects of different concentrations of genistein (1, 3, 5 and 10 μM/100 mL medium) were separately administered one by one to female and male populations of D. melanogaster for application groups. In the control group, the maximum life span was determined to be 57 days for ♀♀, 46 for ♂♂. The maximum life span for the lowest (1.0 μL) and highest (10.0 μL) application groups among the adult populations of D. melanogaster subjected to genistein were observed to be 54, 50, 40 and 36 days for ♀♀ and 51, 48, 40 and 33 days for ♂♂. These values indicate a negative correlation (R = 0.513 for ♂♂ and R = 0.509 for ♀♀) between the maximum life span of the application groups and changing genistein concentrations.
Department of Biology, Faculty of Art and Science, Erzincan University, 24100 Erzincan, Turkey.
Deniz
D
Altun
Handan
H
Uysal
Hakan
H
Aşkın
Arif
A
Ayar
D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects*; D005260:Female; D019833:Genistein / Q000633:toxicity*; D008136:Longevity / Q000187:drug effects*; D008297:Male; D018384:Oxidative Stress; D048789:Phytoestrogens / Q000633:toxicity*; D012737:Sex Factors
D048789:Phytoestrogens; D019833:Genistein