pKas of the conjugate acids of N-heterocyclic carbenes in water.
pK(a) values of 19.8-28.2 are reported for the conjugate acids of a large series of NHCs in water. The effects of ring size, N-substituent and C(4)-C(5) saturation on pK(a) are discussed.
Department of Chemistry, University Science Laboratories, South Road, Durham DH1 3LE, UK.
Eleanor M
EM
Higgins
Jennifer A
JA
Sherwood
Anita G
AG
Lindsay
James
J
Armstrong
Richard S
RS
Massey
Roger W
RW
Alder
AnnMarie C
AC
O'Donoghue