Dehydroepiandrosterone in follicular fluid is produced locally, and levels correlate negatively with in vitro fertilization outcomes.
Follicular fluid DHEA is produced in part within the ovary. Although follicular DHEA correlated with estradiol and testosterone, it correlated negatively with oocyte and embryo quality.
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York 10032, USA. ll2589@columbia.edu
Liyun
L
Li
Michel
M
Ferin
Mark V
MV
Sauer
Rogerio A
RA
Lobo
D000328:Adult; D003687:Dehydroepiandrosterone / Q000032:analysis* / Q000378:metabolism; D004622:Embryo, Mammalian / Q000473:pathology; D005260:Female; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D009865:Oocytes / Q000473:pathology; D009994:Osmolar Concentration; D011247:Pregnancy; D011379:Prognosis; D011786:Quality Control; D016896:Treatment Outcome
D003687:Dehydroepiandrosterone