Osteosarcoma of the mandible--second cancer in a case of Hodgkin's lymphoma post-chemotherapy.
Osteosarcoma as a second cancer occurring in an adolescent male previously treated with only chemotherapy for Hodgkin's lymphoma is rare. A 14 year old male presented with gradual swelling of right jaw and numbness of lip and chin for last three months. He was treated with only chemotherapy for Hodgkin's lymphoma four years back. Incisional biopsy was taken from mandibular swelling, histopathology suggesting osteosarcoma. Right hemimandibulectomy and reconstruction with metallic implant were done along with excision of right parotid lymph node. Chemotherapy was started with cisplatin and doxorubicin regimen. Absence of radiation as a risk factor and very young age of the patient presenting with a second cancer made this case a rarity and hence the case is being reported.
Department of Radiotherapy, Medical College Hospitals, 88 College Street, Kolkata 700 073, West Bengal, India.
Sumitava
S
De
Suparna
S
Ghosh
Dodul
D
Mondal
Prabir K
PK
Sur
D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007573:Jaw Neoplasms / Q000139:chemically induced*; D008297:Male; D016609:Neoplasms, Second Primary / Q000139:chemically induced*; D012516:Osteosarcoma / Q000139:chemically induced*
D000970:Antineoplastic Agents