H1N1-associated acute respiratory distress syndrome.
The worldwide 2009-2010 pandemic of novel H1N1 influenza reminds us that influenza can still be a lethal disease. Acute lung injury and acute respiratory distress syndrome (ARDS) have been the most devastating complications of this pathogen. We present a case of a previously healthy 40-year-old obese man who succumbed to H1N1-associated ARDS. In this focused review, we discuss the pathophysiologic peculiarities and management of acute lung injury/ARDS related to H1N1 infection.
Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA. tnarul@lsuhsc.edu
Tathagat
T
Narula
Mathew
M
Safley
Bennett P
BP
deBoisblanc
D055371:Acute Lung Injury / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D015199:Extracorporeal Membrane Oxygenation; D005440:Fluid Therapy; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications* / Q000188:drug therapy; D008297:Male; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D016879:Salvage Therapy
D000900:Anti-Bacterial Agents; D000998:Antiviral Agents