Lichtheimia corymbifera subcutaneous infection successfully treated with amphotericin B, early debridement, and vacuum-assisted closure.
Lichtheimia corymbifera (syn. Absidia corymbifera, Mycocladus corymbifer) is an ubiquitous cosmopolitan mold that can cause primary cutaneous and deep tissue infection in healthy individuals. We report a subcutaneous L. corymbifera infection in a 13-year-old immune-competent child, with a severe traumatic injury, with a successful outcome after early diagnosis and treatment with lipid amphotericin B, early debridement, and vacuum-assisted closure (VAC).
Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain. danielblazquez@hotmail.com
Daniel
D
Blazquez
Jesús
J
Ruiz-Contreras
Elisa
E
Fernández-Cooke
Ignacio
I
González-Granado
Maria Dolores
MD
Delgado
Maria Teresa
MT
Menendez
Yolanda
Y
Rodriguez-Gil
Aida
A
Ballen
Amalia
A
Del Palacio
D020095:Absidia / Q000302:isolation & purification*; D000063:Accidents, Traffic; D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology; D003131:Combined Modality Therapy; D003161:Compartment Syndromes / Q000209:etiology / Q000601:surgery*; D003646:Debridement; D042241:Early Diagnosis; D050723:Fractures, Bone / Q000150:complications; D006801:Humans; D007121:Immunocompetence; D007867:Leg Bones / Q000293:injuries; D008297:Male; D009091:Mucormycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D009104:Multiple Trauma; D054843:Negative-Pressure Wound Therapy; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D014946:Wound Infection / Q000150:complications
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B