Reply to the letter by Filik and Biyikoglu regarding the hypothesis that changes in the extracellular matrix incurred by systemic hernia disease (herniosis) are hostile to the development of colon cancer.
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D003110:Colonic Neoplasms / Q000150:complications; D043963:Diverticulosis, Colonic / Q000150:complications; D005109:Extracellular Matrix / Q000502:physiology*; D006801:Humans