Controversies in skull reconstruction.
In the early 1980s, it was shown that bone from the skull (membranous bone) maintained its volume to a significantly greater extent than bone from the rib and iliac crest regions (endochondral bone). However, the reason for this enhanced volume maintenance was not clarified for many years. On the basis of this enhanced volume maintenance, cranial bone became the ideal autogenous graft of choice for hard tissue repair. In the ensuing years, the current authors performed a large number of autogenous split skull cranial bone cranioplasties with significant success. However, the lure of an off-the-shelf material that obviates bone harvest remained. From 1995 to 2005, the senior author performed 20 full-thickness skull defect cranioplasty corrections using calcium phosphate cement (Norian Craniofacial Repair System; Synthes, Inc, West Chester, PA; Stryker-Leibinger, Kalamazoo, MI). Of these full-thickness defects, 16 were large (arbitrarily defined as greater than 25 cm2). In this paper, we report our long-term major and minor complication rates using this material. Because of our high, long-term complication rate (38%), we believe this material is contraindicated for large, full-thickness, skull defects (>25 cm2) and we have returned to autogenous cranial bone as the criterion standard for reconstruction in such patients.
Department of Plastic Surgery, Cleveland Clinic, Cleveland, Ohio, USA. zinsj@ccf.org
James E
JE
Zins
Claude-Jean
CJ
Langevin
Serdar
S
Nasir
D000328:Adult; D001672:Biocompatible Materials; D001843:Bone Cements / Q000627:therapeutic use*; D001847:Bone Diseases / Q000145:classification / Q000601:surgery*; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods; D002130:Calcium Phosphates / Q000627:therapeutic use*; D000075202:Contraindications; D005624:Frontal Bone / Q000601:surgery; D006801:Humans; D008137:Longitudinal Studies; D009777:Occipital Bone / Q000601:surgery; D010020:Osteonecrosis / Q000601:surgery; D010294:Parietal Bone / Q000601:surgery; D011183:Postoperative Complications / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D012086:Reoperation; D012886:Skull / Q000601:surgery*; D013526:Surgical Mesh; D013530:Surgical Wound Infection / Q000601:surgery; D020858:Tissue and Organ Harvesting / Q000379:methods; D014025:Titanium; D014182:Transplantation, Autologous
D001672:Biocompatible Materials; D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; C020243:calcium phosphate; D014025:Titanium