Overactive bladder and outlet obstruction in men.
Lower urinary tract symptoms (LUTS), overactive bladder, (OAB), and benign prostatic hyperplasia (BPH) are very commonly experienced in men. The mainstay of pharmacotherapy for OAB is the antimuscarinic class of drugs. There has been reluctance to prescribe these agents to men with BPH due to the risk of precipitating urinary retention. Several trials have supported the efficacy and safety of antimuscarinics in treating men with LUTS, alone, or in combination with α-blocker therapy. The combination of 5-α-reductase inhibitors with antimuscarinic agents or surgery are other effective treatments for men with BPH and OAB.
Mount Sinai Hospital, University of Chicago, IL 60608, USA.
Doreen E
DE
Chung
Jaspreet S
JS
Sandhu
D006801:Humans; D008297:Male; D001748:Urinary Bladder Neck Obstruction / Q000150:complications / Q000628:therapy; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000628:therapy