Epithelioid hemangioendothelioma of the facial bone.
The epithelioid hemangioendothelioma is an uncommon vascular neoplasm. Numerous sites of involvement are possible, but these tumors most commonly arise in the soft tissues, liver, and lung. We report a case of epithelioid hemangioendothelioma presenting as a single lesion on the nasal portion of the maxilla. Histologically, the tumor within bone and skin exhibited cords and nests of plump, epithelioid-appearing cells exhibiting rudimentary vascular differentiation within a myxohyaline stroma. Immunohistochemical reactivities for factor VIII-related antigen, CD31, CD34, and vimentin were demonstrated. Wide local excision with close clinical follow-up seems to be the treatment of choice for these tumors.
Department of Plastic and Reconstructive Surgery, Policlinico Casilino University of Rome Tor Vergata, Rome, Italy.
Davide J
DJ
Bottini
Pietro
P
Gentile
Paola
P
Ascenzi
Vincenzo
V
Galante
Antonio
A
Ricci
Valerio
V
Cervelli
D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis; D015622:Epithelioid Cells / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis*; D006801:Humans; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis*; D009296:Nasal Cavity / Q000473:pathology*; D009669:Nose Neoplasms / Q000175:diagnosis*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D014746:Vimentin / Q000032:analysis; D014841:von Willebrand Factor / Q000032:analysis
D018952:Antigens, CD34; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D014746:Vimentin; D014841:von Willebrand Factor