Correlation between fluorodeoxyglucose positron emission tomography and magnetic resonance imaging findings of non-suppurative meningoencephalitis in 5 dogs.
This study characterized the [(18)F]2-deoxy-2-fluoro-D-glucose positron emission tomography (FDG-PET) findings of encephalitis in dogs and assessed the role of FDG-PET in the diagnosis of meningoencephalitis. The medical records, magnetic resonance (MR), and FDG-PET images of 3 dogs with necrotizing meningoencephalitis (NME), 1 dog with granulomatous meningoencephalitis (GME), and 1 dog with meningoencephalitis of unknown etiology (MUE) were reviewed. On the FDG-PET, glucose hypometabolism was identified in the dog with NME, whereas hypermetabolism was noted in the dog with GME. The T2-weighted images (WI) and fluid attenuated inversion recovery (FLAIR) images were characterized by hyperintensity, whereas the signal intensity of the lesions on the T1-WI images was variable. The metabolic changes on the brain FDG-PET corresponded well to the hyper- and hypointense lesions seen on the MR imaging. This type of tomography (FDG-PET) aided in the differentiation of different types of inflammatory meningoencephalitis when the metabolic data was combined with clinical and MR findings.
Department of Veterinary Internal Medicine, Konkuk University, Seoul, South Korea.
Byeong-Teck
BT
Kang
Seung-Gon
SG
Kim
Chae-Young
CY
Lim
Su-Hyun
SH
Gu
Dong-Pyo
DP
Jang
Young-Bo
YB
Kim
Dae-Young
DY
Kim
Eung-Je
EJ
Woo
Zang-Hee
ZH
Cho
Hee-Myung
HM
Park
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004285:Dogs; D005260:Female; D019788:Fluorodeoxyglucose F18; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D049268:Positron-Emission Tomography / Q000662:veterinary*
D001786:Blood Glucose; D019788:Fluorodeoxyglucose F18