Label-free electrochemical impedance sensing of DNA hybridization based on functionalized graphene sheets.
Negative-charge change and conformation transition upon DNA immobilization and hybridization on functionalized graphene sheets were monitored by the EIS technique and adopted as the signal for label-free electrochemical DNA hybridization detection.
Engineering Laboratory for Modern Analytical Techniques, c/o State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
Yuwei
Y
Hu
Fenghua
F
Li
Xiaoxue
X
Bai
Dan
D
Li
Shucheng
S
Hua
Kaikai
K
Wang
Li
L
Niu
D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D017097:Electric Impedance; D004563:Electrochemistry; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D009693:Nucleic Acid Hybridization / Q000379:methods*; D010569:Perylene / Q000031:analogs & derivatives / Q000737:chemistry; D013057:Spectrum Analysis; D013194:Staining and Labeling
D010569:Perylene; D006108:Graphite; D004247:DNA