Deproteinized bovine bone in periodontal and implant surgery.
OBJECTIVE
To review the histological and clinical outcomes of deproteinized bovine bone in different procedures: periodontal regeneration, socket preservation, peri-implant reconstruction and alveolar bone augmentation.


METHODS
Histological animal studies and clinical trials on humans regarding the performances of a bone substitute of natural origin, deproteinized bovine bone, have been evaluated. Different procedures have been examined separately.


RESULTS
Osteoconductive properties of the material are accepted by the majority of authors. In periodontal regeneration deproteinized bovine bone seems to be effective with or without barrier membranes in favorable containing defects, resulting in histological evidence of periodontal regeneration, with a prevalence of bone repair. Although some reports describe a lower reduction in socket height and width with various techniques and the grafting of deproteinized bovine bone, there is no evidence to recommend socket filling or manipulation to preserve its dimensions. Peri-implant reconstruction and alveolar ridge augmentation utilizing deproteinized bovine bone are supported by favorable reports but these procedures are affected by a significant amount of adverse events that may jeopardize the success of the treatment.


CONCLUSIONS
Deproteinized bovine bone possesses osteoconductive properties that may improve bone regeneration of favorable containing periodontal defects. No evidence supports socket filling and peri-implant reconstruction.
Department of Periodontics and Fixed Prostheses, Faculty of Odontology, University of Siena, Italy. baldini.nicola@gmail.com
N
N
Baldini
M
M
De Sanctis
M
M
Ferrari
D000540:Alveolar Ridge Augmentation; D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D002417:Cattle; D015921:Dental Implants; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008903:Minerals / Q000627:therapeutic use; D010012:Osteogenesis / Q000502:physiology; D010510:Periodontal Diseases / Q000601:surgery*; D019651:Plastic Surgery Procedures; D014021:Tissue Preservation / Q000379:methods
C077540:Bio-Oss; D018786:Bone Substitutes; D015921:Dental Implants; D008903:Minerals