Macular disease affects the outcome of ZyWave aberrometry.
OBJECTIVE
wavefront analysis aims to measure aberrations in the eye, often before and after surgeries. The Hartmann-Shack instrument is an outgoing reflective aberrometer that uses a laser light source. The authors aimed to evaluate changes in aberrations of the eyes with macular irregularity by comparing with the fellow normal eyes.


METHODS
in a prospective study, the authors evaluated both eyes of patients with unilateral acquired foveal lesion by ZyWave (ZyWave; Milwaukee, WI) aberrometer. Eighteen eyes of 9 patients with a mean age of 32 years were examined.


RESULTS
after exclusion of two cases with central serous chorioretinopathy (due to smooth macular surface), a statistically significant increase in higher-order aberration in the involved eyes compared with the normal fellow eyes (P = .043) was found. There was also a statistically significant increase in horizontal trefoil in the involved eyes compared with normal eyes (P = .04).


CONCLUSIONS
this fellow eye study shows that macular irregularity might increase high-order aberrations measured by the Hartmann-Shack aberrometer.
Eye Research Center and Department of Ophthalmology, Khatam-al-Anbia Eye Center, Mashhad University of Medical Sciences, Mashhad, Iran. zareis@mums.ac.ir
Siamak
S
Zarei-Ghanavati
Touka
T
Banaee
Mojtaba
M
Abrishami
Ali
A
Dehghani
D057128:Aberrometry; D000328:Adult; D057108:Corneal Wavefront Aberration / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D012164:Retinal Diseases / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D055815:Young Adult