Hospital initiation of a vaccinal schedule improves the long-term vaccinal coverage of ex-preterm children.
Preterm infants are experiencing delays in receiving routine schedule vaccines. We evaluated up-to-date immunisation status of 602 preterm infants at 5 and 24 months for DTCoqPolioHib and pneumococcal conjugate vaccine (defined by 3 and 4 doses, respectively). At 5 months, 39% (CI 95% [35-43]) of children were up-to-date for DTCoqPolioHib and 22% (CI 95% [19-26]) for pneumococcal conjugate, while at 24 months 67% (CI 95% [64-71]) were up-to-date for DTCoqPolioHib and 36% (CI 95% [32-40]) for pneumococcal conjugate. After adjustment for gestational age, a primary vaccine before discharge remained linked with a better vaccinal coverage (p<.005, OR=5.0; CI 95% [2.9-8.5]).
Department of Neonatal Medicine, Nantes University Hospital, Nantes, France. sophie.denizot@chu-nantes.Fr
S
S
Denizot
J
J
Fleury
G
G
Caillaux
V
V
Rouger
J-C
JC
Rozé
C
C
Gras-Le Guen
D002675:Child, Preschool; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage*; D018073:Haemophilus Vaccines / Q000008:administration & dosage*; D006761:Hospitals; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D007231:Infant, Newborn; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage*; D047928:Premature Birth; D014611:Vaccination / Q000379:methods*; D017778:Vaccines, Combined / Q000008:administration & dosage; D016903:Drug Monitoring
C513012:DTP-IPV-Hib vaccine; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D018073:Haemophilus Vaccines; D022242:Pneumococcal Vaccines; D011054:Poliovirus Vaccine, Inactivated; D017778:Vaccines, Combined