Development of practical methodologies for the synthesis of novel 3(4-oxo-4H-chromen-3-yl)acrylic acid hydrazides.
We report a new environmentally-benign, convenient and facile methodology for the synthesis of new series of 3(4-oxo-4H-chromen-3-yl)acrylic acid hydrazides derivatives designed by exploring the molecular hybridization approach between isoniazide and 3(4-oxo-4H-chromen-3-yl)acrylic acids by using EDCl/HOBt under ultrasound irradiation in very short reaction time. Utilization of easy reaction conditions, isolation and purification makes this manipulation very interesting from an economic perspective.
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India.
Ratnadeep S
RS
Joshi
Priyanka G
PG
Mandhane
Pravin V
PV
Badadhe
Charansingh H
CH
Gill
D055772:Green Chemistry Technology / Q000379:methods*; D006834:Hydrazines / Q000138:chemical synthesis* / Q000737:chemistry*; D007700:Kinetics; D014465:Ultrasonics
D006834:Hydrazines