TfOH-catalyzed tandem cyclopropane ring enlargement/C-C formation/etherification of alkynylcyclopropanes and 1,3-diketones to cyclobutane-fused dihydrofurans.
A new type of TfOH-catalyzed tandem cyclopropane ring enlargement/C-C formation/etherification reaction between alkynylcyclopropanes and 1,3-diketones to cyclobutane-fused dihydrofurans is described. The reaction tolerates a range of aryl and alkyl substituents with moderate to good yields.
Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.
Siyu
S
Ye
Zhi-Xiang
ZX
Yu
D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D003503:Cyclobutanes / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*
D003503:Cyclobutanes; D003521:Cyclopropanes; D004987:Ethers; D005663:Furans; D007659:Ketones; D008698:Mesylates; D002244:Carbon; C030797:cyclopropane; C012077:trifluoromethanesulfonic acid