[Eosinophilia and a solid tumour: ovarian sarcoma].
A 50-year-old woman developed blood eosinophilia during admission to hospital in connection with abdominal symptoms. Eosinophilia is associated with a broad variety of diseases. The major causes of eosinophilia, i.e. an allergic reaction, a parasitic infection and a haematological malignancy, were ruled out. An ultrasound of the abdomen showed a large tumour in the lower abdomen which, because of the patient's history, was attributed to a uterine myoma. Later, this tumour proved to be a mesenchymal malignancy, and surgery was performed to remove it. Histopathology confirmed a high grade sarcoma which had its origin in the right ovary. It is known that eosinophilia can be a paraneoplastic sign of several carcinomas, but it has only infrequently been described in sarcomas. The pathophysiology of tumour-associated eosinophilia is unknown.
Flevoziekenhuis, Almere, Afd. Interne Geneeskunde, the Netherlands.
Suzan P
SP
Van Mens
Marrije R
MR
Buist
Armin W
AW
Walter
Servaas H A
SH
Peters
D004802:Eosinophilia / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D012509:Sarcoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery