[Treatment options of acral ulcers in MCTD].
In patients with systemic sclerosis or mixed connective tissue disease (MCTD) acral ulcers are considered as frequent manifestations that may lead to amputation and loss of function, respectively, as a result of secondary Raynaud's phenomenon. Thus it is necessary to take advantage of all available medical and supportive measures. Adjuvant treatments such as hyperbaric oxygenation and regional sympathetic block represent interdisciplinary treatment options to improve oxygenation of critical ischemia and analgesia and should be subject of further investigation.
Universitätsklinik und Poliklinik für Innere Medizin II, Universitätsklinikum Halle (Saale), Halle (Saale), Germany. ann-kristin.herink@medizin.uni-halle.de
Ann-Kristin
AK
Herink
Lars
L
Köthe
Matthias
M
Girndt
Gernot
G
Keysser
D000328:Adult; D000577:Amides; D016058:Analgesia, Patient-Controlled; D015901:Angiography, Digital Subtraction; D001340:Autonomic Nerve Block; D001379:Azathioprine / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D006931:Hyperbaric Oxygenation; D016285:Iloprost / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D008947:Mixed Connective Tissue Disease / Q000628:therapy*; D009543:Nifedipine / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D011928:Raynaud Disease / Q000628:therapy*; D000077212:Ropivacaine; D012883:Skin Ulcer / Q000628:therapy*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000577:Amides; D014665:Vasodilator Agents; D000077212:Ropivacaine; D011239:Prednisolone; D009543:Nifedipine; D016285:Iloprost; D001379:Azathioprine