Eruptive molluscum contagiosums in a patient with rheumatoid arthritis and lung cancer.
A 67-year-old woman with rheumatoid arthritis (RA) treated with systemic prednisolone and methotrexate over 20 years developed eruptive molluscum contagiosums on the trunk and extremities. Investigation revealed lung cancer 2 years later. Newly development of molluscum contagiosums ceased after the surgical operation of lung cancer. Immunologic dysfunctions have been shown in RA, and especially patients under long-term methotrexate therapy are susceptible to miscellaneous skin conditions. Eruptive molluscum contagiosums are induced in association with hematologic malignancies such as lymphoma, leukemia, and HIV infection; however, it is important to investigate internal malignancies, not only hematologic malignancies but also solid cancers, when patients with RA under immunosuppressive therapies presented eruptive or disseminated molluscum contagiosums.
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
Taeko
T
Nakamura-Wakatsuki
Yasunobu
Y
Kato
Takako
T
Miura
Toshiyuki
T
Yamamoto
D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D008727:Methotrexate / Q000627:therapeutic use; D008976:Molluscum Contagiosum / Q000150:complications / Q000473:pathology* / Q000628:therapy; D011013:Pneumonectomy
D018501:Antirheumatic Agents; D008727:Methotrexate