Dietary uptake kinetics of polychlorinated biphenyls from sediment-contaminated sandworms in a marine benthic fish (Pseudopleuronectes yokohamae).
To evaluate the dietary uptake of polychlorinated biphenyls (PCBs) from live food, we investigated the dietary uptake and depuration kinetics of PCBs in a marine benthic fish (marbled sole, Pseudopleuronectes yokohamae) by using as food live sandworms (Perinereis nuntia) that were laboratory-exposed to field-collected PCB-contaminated sediment. Marbled sole were fed the PCB-contaminated sandworms for 28d and then uncontaminated sandworms for 56d. The assimilation efficiencies (AEs) of 84 PCB congeners via the gastrointestinal tract (GIT) to the muscle of the fish ranged from 0.21 to 0.78; whole-body AEs would be lower than those of muscle because of the lower PCB concentrations, on a lipid basis. The AEs determined in this study were lower than those in other studies that used PCB-spiked commercial pelletized food. The lower AEs found in this study might be attributable to differences in the food administered (live sandworms vs. commercial pellet food), possibly because of low digestibility of sandworm lipids by marbled sole. In addition, the AEs in this study tended to increase with increasing log octanol-water partition coefficients (K(OW)) up to about seven, although AEs in the other studies using commercial pelletized food did not increase with increasing logK(OW). This result suggests the co-transport of highly hydrophobic PCB congeners along with lipids and fatty acids from the digested sandworms into the GIT epithelium cells. The growth-corrected half-lives of 26 PCB congeners in the muscle of fish ranged from 20 to 107d.
Research Center for Environmental Risk, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan. kobayashi.jun@nies.go.jp
Jun
J
Kobayashi
Kyoko
K
Kinoshita
Kaoruko
K
Mizukawa
Takeo
T
Sakurai
Yoshitaka
Y
Imaizumi
Hideshige
H
Takada
Noriyuki
N
Suzuki
D000818:Animals; D001692:Biological Transport; D004032:Diet; D005432:Flounder / Q000378:metabolism*; D019015:Geologic Sediments / Q000737:chemistry; D006207:Half-Life; D007700:Kinetics; D011077:Polychaeta / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000008:administration & dosage / Q000493:pharmacokinetics*; D014874:Water Pollutants, Chemical / Q000008:administration & dosage / Q000493:pharmacokinetics*
D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls