[Changing prognosis and treatment of gastric cancer].
The most important factor affecting the prognosis of gastric cancer is the extent of the disease at the time of diagnosis. Surgical excision of the tumor is a prerequisite for curative treatment. The patient's prognosis may improve, if cytotoxic therapy is started already before surgical treatment and continued after the treatment. This so-called perioperative cytotoxic therapy also reduces tumor mass. Concomitant chemoradiotherapy has resulted in a prolonged disease-free life span and total life span. It is worthwhile to treat even a disseminated gastric cancer with cytotoxic drugs, and the first targeted therapy is already available.
TYKS:n syöpätautien klinikka, Turku.
Raija
R
Ristamäki
Paulina
P
Salminen
Arto
A
Kokkola
Ari
A
Ristimäki
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000532:radiotherapy