Somatic signals counteract reproductive aging in females.
Recent research shows that declining oocyte quality with age is not inevitable in nematodes, and similar signals might regulate reproductive aging in women.
Department of Molecular Biology, The University of Medicine and Dentistry of New Jersey, B303 Science Center, 2 Medical Center Drive, Stratford, NJ 08084, USA. Ron.ellis@umdnj.edu
Ronald E
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Ellis
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D000375:Aging; D000818:Animals; D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008423:Maternal Age; D009348:Nematoda / Q000502:physiology; D009865:Oocytes / Q000254:growth & development*; D012098:Reproduction; D015398:Signal Transduction; D053773:Transforming Growth Factor beta1 / Q000378:metabolism
D007328:Insulin; D053773:Transforming Growth Factor beta1; D007334:Insulin-Like Growth Factor I