Effect of allofibroblast transplantation on the wound process and its outcomes in burned patients.
Clinical and morphological studies of the effects of allofibroblast transplantation on the wound process were carried out in patients with extensive deep burns. Transplantation of allofibroblast culture stimulated the reparation process, promoted rapid increase in the counts of fibroblasts and functionally active macrophages, formation of normal granulation tissue, and early effective autodermoplasty. Transplantation reduced the number of operations and treatment duration and costs and ensured better esthetic results.
Russian Medical Academy for Postgraduate Education, Ministry of Health Care and Social Development, Moscow, Russia. a.alexseev@rambler.ru
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Alekseyev
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Fistal
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Podurets
D000293:Adolescent; D000328:Adult; D000368:Aged; D002056:Burns / Q000628:therapy*; D017690:Cell Transplantation / Q000379:methods*; D005347:Fibroblasts / Q000637:transplantation*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*