[Current indications of lymphadenectomy in endometrial cancer].
Endometrial cancer is a tumor associated with a good prognosis as it is often diagnosed at an early stage. Up to 20 % of patients with stage I disease have a nodal involvement. Knowledge of nodal status provides important prognostic information. As preoperative assessment yields a poor value, prognostic lymphadenectomy appears to be indicated. However, therapeutic benefit of pelvic and para-aortic lymphadenectomy remains controversial. Recent randomized trials did not find any impact on survival for patients with low risk of nodal involvement. Thus, lymphadenectomy should no more be systematically performed in this low risk group. Nevertheless, pelvic and para-aortic lymphadenectomy seems to have a benefit in the high risk group, as isolated involved para-aortic nodes have been described.
Service de chirurgie gynécologique et cancérologique, hôpital européen Georges-Pompidou, AP-HP, 20 rue Leblanc, Paris, France. anne-sophie.bats@egp.aphp.fr
A-S
AS
Bats
C
C
Bensaïd
C
C
Huchon
C
C
Scarabin
C
C
Nos
F
F
Lécuru
D018269:Carcinoma, Endometrioid / Q000401:mortality* / Q000601:surgery*; D016889:Endometrial Neoplasms / Q000401:mortality* / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic