Invariance kernel of biological regulatory networks.
The analysis of Biological Regulatory Network (BRN) leads to the computing of the set of the possible behaviours of the biological components. These behaviours are seen as trajectories and we are specifically interested in cyclic trajectories since they stand for stability. The set of cycles is given by the so-called invariance kernel of a BRN. This paper presents a method for deriving symbolic formulae for the length, volume and diameter of a cylindrical invariance kernel. These formulae are expressed in terms of delay parameters expressions and give the existence of an invariance kernel and a hint of the number of cyclic trajectories.
IRCCyN UMR CNRS 6597, BP 92101, 1 rue de la Noë, 44321 Nantes Cedex 3, France. jamil.ahmad@irccyn.ec-nantes.fr
Jamil
J
Ahmad
Olivier
O
Roux
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D053858:Metabolic Networks and Pathways; D008954:Models, Biological