[Significance of TDM, phenotyping and genotyping for the correct drug dosage].
Therapeutic drug monitoring is a specific method of clinical pharmacology for monitoring of the therapy using measurement of drug serum concentrations followed by interpretation and good cooperation with clinician. It significantly helps to personalize and rationalize the treatment, to set individualized dosing, to minimize side effects, to decrease mortality and morbidity and to decrease the costs. Phenotyping and genotyping can increase therapeutic drug monitoring on higher level.
Ostravská univerzita, Lékarská fakulta a Fakultní nemocnice Ostrava, Ustavy klinické farmakologie. milan.grundmann@fno.cz
Milan
M
Grundmann
Ivana
I
Kacírová
D054796:Drug Dosage Calculations; D016903:Drug Monitoring; D005838:Genotype; D006801:Humans; D010599:Pharmacokinetics; D010641:Phenotype; D057285:Precision Medicine