Rehabilitation of irradiated patients with modified and conventional sandblasted acid-etched implants: preliminary results of a split-mouth study.
OBJECTIVE
The aim of this study was to evaluate the success rate of chemically modified and conventional sandblasted acid-etched surface (SLA) titanium implants in irradiated oral squamous cell carcinoma patients.


METHODS
Twenty patients with a mean age of 61.1 years were treated with dental implants after ablative surgery and radio-chemotherapy of oral cancer. All patients were non-smokers. The placement of SLA and modSLA implants was performed bilaterally according to a split-mouth design. All 102 implants (50 SLA, 52 modSLA) placed showed an unloaded healing time of 6 weeks in the mandible and 10 weeks in the maxilla. Mean crestal bone changes using standardized orthopantomographies and clinical parameters like pocket depths, mPII and mBI were evaluated.


RESULTS
Of 102 implants, 55 implants (27 SLA implants, 28 modSLA) were located in the maxilla and 47 implants (23 SLA, 24 modSLA) in the mandible. The average observation period was 14.4 months. The amount of bone loss at the implant shoulder of SLA implants was 0.4 mm mesial and 0.4 mm distal. The modSLA implants displayed a bone loss of mesial 0.3 mm and distal 0.3 mm. Two SLA implants were lost resulting in a success rate of 96%. The success rate of modSLA implants was 100%.


CONCLUSIONS
Regarding the data found in this investigation, we can conclude that implants with chemically modified and conventional SLA titanium surface show high success rates in irradiated patients. SLA implants with or without a chemically modified surface regardless of the location can be restored with a high predictability of success at least in the short time range observed.
Department of Oral and Maxillofacial Surgery, Navigation and Robotics, Berlin, Germany. Susanne.Heberer@charite.de
Susanne
S
Heberer
Sevtap
S
Kilic
Jaber
J
Hossamo
Jan-Dirk
JD
Raguse
Katja
K
Nelson
D000134:Acid Etching, Dental / Q000379:methods*; D000368:Aged; D016301:Alveolar Bone Loss / Q000145:classification; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D045662:Dental Etching / Q000379:methods*; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000528:radiation effects / Q000601:surgery; D008339:Mandibular Neoplasms / Q000532:radiotherapy*; D008437:Maxilla / Q000000981:diagnostic imaging / Q000528:radiation effects / Q000601:surgery; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000145:classification; D011859:Radiography; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D016896:Treatment Outcome
D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium