Copper-catalyzed intermolecular oxidative [3 + 2] cycloaddition between alkenes and anhydrides: a new synthetic approach to γ-lactones.
A new copper-catalyzed oxidative [3 + 2] cycloaddition of alkenes with anhydrides using oxygen as the sole oxidant to afford γ-lactones has been developed. This catalyzed cyclization process has a broad substrate scope and affords γ-lactones in good to excellent yields.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China.
Liangbin
L
Huang
Huanfeng
H
Jiang
Chaorong
C
Qi
Xiaohang
X
Liu
D000475:Alkenes / Q000737:chemistry*; D000812:Anhydrides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D000475:Alkenes; D000812:Anhydrides; D007783:Lactones; D003300:Copper