Treg cell-IgA axis in maintenance of host immune homeostasis with microbiota.
The intestine is the home to a vast diversity of microbiota and a complex of mucosal immune system. Multiple regulatory mechanisms control host immune responses to microbiota and maintain intestinal immune homeostasis. This mini review will provide evidence indicating a Treg cell-IgA axis and such axis playing a major role in maintenance of intestinal homeostasis.
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555-1019, USA.
Ting
T
Feng
Charles O
CO
Elson
Yingzi
Y
Cong
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D006706:Homeostasis; D054884:Host-Pathogen Interactions; D006801:Humans; D018928:Immunity, Mucosal; D007070:Immunoglobulin A / Q000276:immunology*; D007422:Intestines / Q000276:immunology* / Q000382:microbiology*; D054892:Metagenome; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000382:microbiology
D000942:Antigens, Bacterial; D007070:Immunoglobulin A