Late recurrence in orbital rhabdomyosarcoma: complete remission after multimodality management.
A case of orbital rhabdomyosarcoma had a localised recurrence 13 years after being treated with chemo radiotherapy. Late recurrences are rare in orbital RMS. Only two cases have been reported to have recurred after five years of follow up. Pathological similarity of both the lesions and occurrence outside the irradiated field excluded a radiation-induced second neoplasm. Immunohistochemistry staining with p 53 was positive. Patient had good response to chemotherapy and radiotherapy. Surgical resection of residue showed complete necrosis. Retreatment with combined modality therapy resulted in complete remission and the patient is on follow up.
Department of Medical Oncology, Cancer Institute, Chennai 36, India. arunrw@yahoo.com
Arun R
AR
Warrier
Sanju
S
Syriac
Krishna Kumar
KK
Rathnam
D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000473:pathology* / Q000628:therapy; D012074:Remission Induction; D012208:Rhabdomyosarcoma / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed