Antiepileptic drugs: the old and the new.
During the past decade several new antiepileptic drugs (AEDs) have become available, including new formulations of some of the older medications. Understanding the pharmacokinetics of the new AEDs is important because they are primarily used for adjunctive therapy and interactions with other medications can result in significant toxicities. The new-generation AEDs do not cause serious morbidity in overdose, and treatment is primarily supportive. Specific medications should be chosen based on the patient's history and presentation.
Department of Emergency Medicine, Morristown Memorial Hospital, Morristown, NJ, USA. ansharma@pol.net
Oliver L
OL
Hung
Richard D
RD
Shih
D000927:Anticonvulsants / Q000009:adverse effects* / Q000145:classification* / Q000493:pharmacokinetics; D062787:Drug Overdose; D006801:Humans
D000927:Anticonvulsants