Citrus residues isolates improve astaxanthin production by Xanthophyllomyces dendrorhous.
The wild strain and two astaxanthin-overproducing mutant strains, W618 and GNG274, of Xanthophyllomyces dendrorhous were analyzed in order to assess their ability to grow and synthesize astaxanthin in a minimal medium containing (per liter): 2 g KH2PO4, 0.5 g MgSO4, 2 g KNO3, and 1 g yeast extract, and supplemented with citrus residues isolates as a carbon source (citrus medium). The selected strain W618 was evaluated under various contents of citrus juice. At the content of 20% (v/v), the highest astaxanthin production reached 22.63 mg L(-1), which was two-fold more than that observed in yeast malt medium. Addition of 8% (v/v) n-hexadecane to the citrus medium was found to be optimal, increasing the astaxanthin yield by 21.7%.
School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China.
Wei
W
Wu
Mingbo
M
Lu
Longjiang
L
Yu
D018533:Biomass; D002957:Citrus / Q000737:chemistry*; D004350:Drug Residues / Q000302:isolation & purification / Q000494:pharmacology*; D024341:Xanthophylls / Q000096:biosynthesis / Q000378:metabolism; D015003:Yeasts / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
D024341:Xanthophylls; C005948:astaxanthine