Does green tea affect postprandial glucose, insulin and satiety in healthy subjects: a randomized controlled trial.
BACKGROUND
Results of epidemiological studies have suggested that consumption of green tea could lower the risk of type 2 diabetes. Intervention studies show that green tea may decrease blood glucose levels, and also increase satiety. This study was conducted to examine the postprandial effects of green tea on glucose levels, glycemic index, insulin levels and satiety in healthy individuals after the consumption of a meal including green tea.


METHODS
The study was conducted on 14 healthy volunteers, with a crossover design. Participants were randomized to either 300 ml of green tea or water. This was consumed together with a breakfast consisting of white bread and sliced turkey. Blood samples were drawn at 0, 15, 30, 45, 60, 90, and 120 minutes. Participants completed several different satiety score scales at the same times.


RESULTS
Plasma glucose levels were higher 120 min after ingestion of the meal with green tea than after the ingestion of the meal with water. No significant differences were found in serum insulin levels, or the area under the curve for glucose or insulin. Subjects reported significantly higher satiety, having a less strong desire to eat their favorite food and finding it less pleasant to eat another mouthful of the same food after drinking green tea compared to water.


CONCLUSIONS
Green tea showed no glucose or insulin-lowering effect. However, increased satiety and fullness were reported by the participants after the consumption of green tea.


BACKGROUND
NCT01086189.
Lund University, Skåne University Hospital, Lund University, Malmö, Sweden.
Julija
J
Josic
Anna Tholén
AT
Olsson
Jennie
J
Wickeberg
Sandra
S
Lindstedt
Joanna
J
Hlebowicz
D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D001939:Bread; D018592:Cross-Over Studies; D005260:Female; D038321:Glycemic Index; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control; D006946:Hyperinsulinism / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000097:blood*; D008297:Male; D008460:Meat; D019518:Postprandial Period; D012528:Satiety Response; D011795:Surveys and Questionnaires; D013662:Tea; D013997:Time Factors; D055815:Young Adult
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D013662:Tea