[Research progress on the relationship between three kinds of liver fluke infections and cholangiocarcinoma].
Liver fluke disease caused by Clonorchis sinensis, Opisthorchis viverrini and O. felineus is a food-borne zoonotic parasitic disease and widely prevalent in Asia. The definitive hosts including human beings get the infection by ingestion of raw or undercooked fish or shrimp infested with metacercariae. Long-term or severe infection of the flukes can lead to dysfunction of the liver, such as cholelithiasis, cholecystitis, and so on. Researches indicated that there is an etiology relation between the fluke infection and cholangiocarcinoma. This paper reviews the relationship and possible mechanisms of the liver fluke-associated cholangiocarcinoma
Key Laboratory of Zoonoses, Ministry of Education, China.
Guo-xing
GX
Liu
Xiu-ping
XP
Wu
Zi-jian
ZJ
Wang
Xue
X
Bai
Ming-yuan
MY
Liu
D000818:Animals; D018281:Cholangiocarcinoma / Q000209:etiology / Q000469:parasitology*; D003004:Clonorchis sinensis; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000150:complications*; D009891:Opisthorchis; D014201:Trematode Infections / Q000150:complications*