Demospongic acids revisited.
The well-known fatty acids with a Δ5,9 unsaturation system were designated for a long period as demospongic acids, taking into account that they originally occurred in marine Demospongia sponges. However, such acids have also been observed in various marine sources with a large range of chain-lengths (C(16)-C(32)) and from some terrestrial plants with short acyl chains (C(18)-C(19)). Finally, the Δ5,9 fatty acids appear to be a particular type of non-methylene-interrupted fatty acids (NMA FAs). This article reviews the occurrence of these particular fatty acids in marine and terrestrial organisms and shows the biosynthetic connections between Δ5,9 fatty acids and other NMI FAs.
Groupe Mer, Molécules, Santé MMS/EA 2160, Equipe 7: Lipides marins à activité biologique, Pôle Mer et Littoral, Faculté de Pharmacie, Université de Nantes, France. jean-michel.kornprobst@univ-nantes.fr
Jean-Michel
JM
Kornprobst
Gilles
G
Barnathan
D000818:Animals; D005227:Fatty Acids / Q000096:biosynthesis / Q000737:chemistry / Q000145:classification / Q000378:metabolism; D009792:Oceans and Seas; D010944:Plants; D011161:Porifera / Q000737:chemistry* / Q000145:classification / Q000378:metabolism*
D005227:Fatty Acids