Sesame seed lignans: potent physiological modulators and possible ingredients in functional foods & nutraceuticals.
Sesame seed contains very high levels (up to 2.5%) of furofuran lignans with beneficial physiological activities, mainly sesamin, sesamolin, and sesaminol glucosides. Reported activities of sesame seed lignans include inter alias modulation of fatty acid metabolism, inhibition of cholesterol absorption and biosynthesis, antioxidant and vitamin E-sparing effects, hypotensive effects, improvement of liver functions in connection with alcohol metabolism, and antiaging effects. This review comprehends patents pertinent to the preparations and uses of sesame seed lignans in health promotion.
Department of Food Science, Swedish University of Agricultural Sciences, Uppsala, Sweden. Afaf.Kamal-Eldin@lmv.slu.se
Afaf
A
Kamal-Eldin
Ali
A
Moazzami
Sidiga
S
Washi
D000375:Aging / Q000187:drug effects; D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D019587:Dietary Supplements; D055951:Functional Food; D006801:Humans; D017705:Lignans / Q000302:isolation & purification / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D010330:Patents as Topic; D012639:Seeds / Q000737:chemistry*; D031685:Sesamum / Q000737:chemistry*
D000924:Anticholesteremic Agents; D000959:Antihypertensive Agents; D000975:Antioxidants; D017705:Lignans