Before you analyze a human specimen, think quality, variability, and bias.
Personalized medicine requires capabilities to detect and measure health-associated biomarkers with increasingly specific and sensitive methods, putting analytical chemists at the front lines of translational research. Analytical scientists must be upstream in the experimental design process because the analysis of a biospecimen (tissue, blood, etc.) presents technical and experimental design complexities. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html.).
AAAS Science and Technology Policy Fellowship Program and National Cancer Institute, National Institutes of Health, USA.
Mark David
MD
Lim
Anthony
A
Dickherber
Carolyn C
CC
Compton
D016477:Artifacts; D001774:Blood Chemical Analysis; D002623:Chemistry Techniques, Analytical; D019963:Clinical Chemistry Tests / Q000379:methods* / Q000592:standards; D006801:Humans; D057285:Precision Medicine; D012015:Reference Standards