A near-fatal infection with oseltamivir-resistant seasonal influenza A in a previously healthy child: Case report.
A case of near-fatal oseltamivir-resistant seasonal influenza A infection in a previously healthy four-year-old boy is reported. This case highlights three important points for physicians: oseltamivir-resistant influenza A (H1N1) has recently emerged in North America; contrary to previously held beliefs, such strains are capable of causing severe disease in healthy children; and given this change in epidemiology, clinicians caring for children with severe seasonal influenza A infection should consider empiric dual therapy with oseltamivir and amantadine.
Infectious Diseases Division, Department of Pediatrics, Montreal Children's Hospital;
Jesse
J
Papenburg
Christos
C
Karatzios
Yan
Y
Li
Nathalie
N
Bastien
Makeda
M
Semret
Dorothy
D
Moore