[Microbiological spectrum of causative agents of rhinogenic and odontogenic chronic sinusitis and mucociliary activity of mucosal epithelium in the nasal cavity].
The objective of the present work was to study peculiarities of microbiological spectra in patients with chronic rhinogenic and odontogenic sinusitis. The secondary objective was to elucidate disturbances of mucociliary activity of mucosal epithelium in the nasal cavity of patients with this pathology. A total of 38 inpatients were examined that were hospitalized for the treatment of chronic maxillary sinusitis. The aspirate from maxillary sinuses was used for bacteriological analysis. The mucociliary transport time was measured in all the patients. It was shown that non-clostridial anaerobic flora isolated in 19.2% of the cases plays a leading role in the development of rhinogenic pathology. Moreover, anaerobic bacteria were responsible for infectious inflammation in 66.7% of the cases with the odontogenic form of chronic sinusitis. The mucociliary transport time in patients with odontogenic sinusitis was significantly greater than in those with the rhinogenic form of the disease (48.9 +/- 4.3 min and 32.35 +/- 3.1 min respectively). It is hypothesized that these findings can be attributed to the action of non-clostridial anaerobic flora on the ciliary epithelium of endonasal mucosa.
P A
PA
Kondrashev
O E
OE
Lodochkina
O N
ON
Opryshko
D000328:Adult; D000368:Aged; D001421:Bacteria, Anaerobic / Q000145:classification* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D015523:Maxillary Sinusitis / Q000382:microbiology* / Q000503:physiopathology*; D008875:Middle Aged; D009079:Mucociliary Clearance; D009297:Nasal Mucosa / Q000382:microbiology*; D014070:Tooth / Q000382:microbiology*; D055815:Young Adult