Pediatric cannabinoid hyperemesis: two cases.
Cannabinoid hyperemesis has recently been described in the literature. It is a syndrome characterized by severe nausea and hyperemesis in the setting of chronic marijuana abuse and, to date, has been described only in adults. We describe the syndrome in 2 pediatric patients, for whom extensive gastrointestinal workups failed to identify a clear cause and cessation of marijuana use resulted in the alleviation of their symptoms. As in most published adult cases, compulsive bathing was present in both of these cases.
Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI 48202, USA. jmiller6@hfhs.org
Joseph B
JB
Miller
Mark
M
Walsh
Pankaj A
PA
Patel
Michael
M
Rogan
Cliff
C
Arnold
Megan
M
Maloney
Michael
M
Donnino
D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications; D001494:Baths; D002188:Cannabis / Q000009:adverse effects*; D015897:Comorbidity; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000150:complications*; D008385:Marijuana Smoking / Q000009:adverse effects*; D009325:Nausea / Q000139:chemically induced / Q000628:therapy; D043884:Receptor, Cannabinoid, CB1 / Q000187:drug effects / Q000502:physiology; D014029:Tobacco Use Disorder / Q000150:complications; D014839:Vomiting / Q000139:chemically induced* / Q000517:prevention & control
D018927:Anti-Asthmatic Agents; D000928:Antidepressive Agents; C543264:Cnr1 protein, rat; D043884:Receptor, Cannabinoid, CB1