Bacterial degradation of fungicide captan.
The phthalimide fungicide captan has been widely used to control plant pathogenic fungi. A strain of Bacillus circulans utilized the fungicide captan as sole source of carbon and energy. The organism degraded captan by a pathway involving its initial hydrolysis to yield cis-1,2,3,6-tetrahydrophthalimide, a compound without fungicidal activity. The formation of this compound was confirmed by HPLC, IR, NMR, and mass spectral analysis. The results also revealed that cis-1,2,3,6-tetrahydrophthalimide was further degraded to o-phthalic acid by a protocatechuate pathway. These findings indicated that there was a complete mineralization of fungicide captan by B. circulans.
Department of Biochemistry, Karnatak University, Dharwad 580 003, Karnataka, India.
Veena B
VB
Megadi
Preeti N
PN
Tallur
Sikandar I
SI
Mulla
Harichandra Z
HZ
Ninnekar
D001407:Bacillus / Q000378:metabolism*; D001673:Biodegradation, Environmental; D002215:Captan / Q000737:chemistry / Q000378:metabolism*; D005659:Fungicides, Industrial / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure
D005659:Fungicides, Industrial; D002215:Captan