[Study on supercritical CO2 extraction of flavonoids from Cynomorium songaricum].
OBJECTIVE
To study the extraction technology of flavonoids from Cynomorium songaricum by supercritical CO2 extraction.


METHODS
The effects of pressure, temperature, time, concentration of alcohol, dosage of chemical preparation, flux of CO2 and particle size were studied by single factor analysis and orthogonal test.


RESULTS
The optimized conditions were as follows: particle size 60 - 80 sieve mesh, the pressure was 30 MPa, the temperature was 50 degrees C, the time was 75 min, concentration of alcohol was 50%, entrainment rate was 8%, flux of CO2 was 5 mL/min. The total flavonoids yield could reach 21.18% under the above conditions.


CONCLUSIONS
This method is simple, rapid and higher extraction yield, so it is suitable for the extraction of flavonoids from Cynomorium songaricum.
College of Arts & Science of Beijing Union University, Beijing 100191, China. luanna@ygi.edu.cn
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D002245:Carbon Dioxide / Q000737:chemistry; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D031482:Cynomorium / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry*; D011312:Pressure; D012997:Solvents / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D005419:Flavonoids; D012997:Solvents; D002245:Carbon Dioxide; D000431:Ethanol