Ocular refractive and biometric characteristics in patients with tilted disc syndrome.
BACKGROUND
Tilted disc syndrome (TDS) is associated with characteristic ocular findings. The purpose of this study was to evaluate the ocular, refractive, and biometric characteristics in patients with TDS.


METHODS
This case-control study included 41 eyes of 25 patients who had established TDS and 40 eyes of 20 healthy control subjects. All participants underwent a complete ocular examination, including refraction and analysis using Fourier transformation, slit lamp biomicroscopy, pachymetry, keratometry, and ocular biometry. Corneal topography examinations were performed in the syndrome group only.


RESULTS
There were no significant differences in spherical equivalent (P = 0.13) and total astigmatism (P = 0.37) between groups. However, mean best spectacle-corrected visual acuity (Log Mar) was significantly worse in TDS patients (P = 0.003). The lenticular astigmatism was greater in the syndrome group, whereas the corneal component was greater in controls (P = 0.059 and P = 0.028, respectively). The measured biometric features were the same in both groups, except for the lens thickness and lens-axial length factor, which were greater in the TDS group (P = 0.007 and P = 0.055, respectively).


CONCLUSIONS
Clinically significant lenticular astigmatism, more oblique corneal astigmatism, and thicker lenses were characteristic findings in patients with TDS.
Department of Ophthalmology, Shiraz University of Medical Sciences, Shiraz, Iran.
Cirous
C
Dehghani
Mohammad Hosein
MH
Nowroozzadeh
Sunita
S
Shankar
Mohammad Reza
MR
Razeghinejad
D000293:Adolescent; D000328:Adult; D001251:Astigmatism / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D016022:Case-Control Studies; D002648:Child; D003315:Cornea / Q000000981:diagnostic imaging / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000002:abnormalities* / Q000000981:diagnostic imaging; D012044:Regression Analysis; D013577:Syndrome; D014463:Ultrasonography