Necrosis of the tongue as first symptom of Polyarteritis Nodosa (PAN): unusual presentation of a rare disease in children.
Polyarteritis or panarteritis nodosa (PAN) is a necrotizing, focal segmental vasculitis that affects predominantly medium-sized arteries in many different organ systems. It is extremely rare in childhood. Involvement of the oral mucosa at diagnosis is uncommon in PAN. Here, we report a case of a pediatric patient with tongue necrosis.
Department of Pediatric Medicine, Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Piazza S. Onofrio, 4, 00135 Rome, Italy. psabrina.buonuomo@opbg.net
Paola Sabrina
PS
Buonuomo
May
M
El Hachem
Francesco
F
Callea
Claudia
C
Bracaglia
Andrea
A
Diociaiuti
Manuela
M
Pardeo
Andrea
A
Campana
Antonella
A
Insalaco
Elisabetta
E
Cortis
Alberto G
AG
Ugazio
D002648:Child; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology*; D009336:Necrosis / Q000209:etiology* / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000473:pathology; D014059:Tongue / Q000473:pathology*