Alopecia in vitamin D-dependent rickets type II responding to 1α-hydroxycholecalciferol.
A 4-year-old boy presented with rickets, alopecia and macrocephaly along with elevated serum levels of 1,25(OH)₂D₃ which was diagnostic of vitamin D-dependent rickets type II. The rickets responded to conventional doses of 1α-hydroxycholecalciferol together with oral calcium supplement and there was also improvement in the alopecia. In patients with vitamin D-dependent rickets type II with alopecia, although rickets improves with treatment, improvement in alopecia has not been reported before.
Department of Pediatrics, Maulana Azad Medical College and Chacha Nehru Bal Chikitsalaya, Delhi, India. vmpd05@yahoo.co.in
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Kumar
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Kumar
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Yadav
D000505:Alopecia / Q000150:complications* / Q000188:drug therapy*; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use; D002675:Child, Preschool; D053098:Familial Hypophosphatemic Rickets / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D006887:Hydroxycholecalciferols / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D058627:Megalencephaly / Q000150:complications / Q000188:drug therapy; D011859:Radiography; D016896:Treatment Outcome; D014807:Vitamin D / Q000378:metabolism
D006887:Hydroxycholecalciferols; D014807:Vitamin D; D002118:Calcium; C008088:alfacalcidol