The renal cyst infection caused by Salmonella enteritidis in a patient with autosomal dominant polycystic kidney disease: how did this pathogen come into the renal cysts?
A 40-year-old Japanese man was admitted to our hospital for investigation of fever and right flank pain starting after watery diarrhea. Salmonella enteritidis was cultured from samples of stool and blood. Although his diarrhea subsided soon, high fever persisted and flank pain got worse. Magnetic resonance imaging (MRI) revealed four areas of abnormal intensity in renal cysts and computed tomography showed the same findings. Renal cysts infection was diagnosed. After ultrasound-guided aspiration of these cysts, his fever subsided. Culture of each aspirate grew Salmonella enteritidis. Although the route of cyst infection in ADPKD generally remains unclear, the clinical course of our patient may indicate that gastrointestinal tract infection progressed to renal cyst infection when bacteremia occurred due to bacterial translocation.
Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya, Takatsu, Kawasaki, Kanagawa 213-8587, Japan.
Yoshiki
Y
Tsuchiya
Yoshifumi
Y
Ubara
Tatsuya
T
Suwabe
Junichi
J
Hoshino
Keiichi
K
Sumida
Rikako
R
Hiramatsu
Eiko
E
Hasegawa
Masayuki
M
Yamanouchi
Noriko
N
Hayami
Yuji
Y
Marui
Naoki
N
Sawa
Fumi
F
Takemoto
Kenmei
K
Takaichi
D000328:Adult; D016470:Bacteremia / Q000150:complications; D005759:Gastroenteritis / Q000150:complications / Q000382:microbiology; D006801:Humans; D007564:Japan; D052177:Kidney Diseases, Cystic / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications*; D012480:Salmonella Infections / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D012477:Salmonella enteritidis / Q000472:pathogenicity*