Comparison of alpha-blocker, extracorporeal magnetic stimulation alone and in combination in the management of female bladder outlet obstruction.
OBJECTIVE
To determine the effects of alpha-blocker, extracorporeal magnetic innervations (ExMI) alone and combination treatment on female bladder outlet obstruction (BOO).


METHODS
Sixty women with BOO were divided into three groups according to the treatment. After 3 months, the clinical outcomes were evaluated by clinical examination, international prostatic symptom score (IPSS), quality of life (QOL), 3-day voiding diary, uroflowmetry and post-void residual.


RESULTS
At 3 months, symptom improvement was 52.6% in alpha-blocker monotherapy (group I), 50.0% in ExMI monotherapy (group II), and 57.1% in combination therapy (group III). Maximum flow rate increased and total IPSS decreased significantly in all groups (p < 0.05). Storage symptom subscore was more reduced in groups II and III and QOL improved significantly in group III (p < 0.05)


CONCLUSIONS
This study demonstrates that both alpha-blocker and ExMI were effective in female BOO, and ExMI may be more effective for improving storage symptoms.
Department of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 2, Sosa-dong, Wonmi-gu, Bucheon-si, Kyunggi-do, South Korea.
Jun Sung
JS
Koh
Su Jin
SJ
Kim
Hyo Sin
HS
Kim
Joon Chul
JC
Kim
D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D055909:Magnetic Field Therapy; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D011799:Quinazolines / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000188:drug therapy* / Q000628:therapy; D014563:Urodynamics
D000317:Adrenergic alpha-Antagonists; D011799:Quinazolines; C047638:alfuzosin