Constructing a fish metabolic network model.
We report the construction of a genome-wide fish metabolic network model, MetaFishNet, and its application to analyzing high throughput gene expression data. This model is a stepping stone to broader applications of fish systems biology, for example by guiding study design through comparison with human metabolism and the integration of multiple data types. MetaFishNet resources, including a pathway enrichment analysis tool, are accessible at http://metafishnet.appspot.com.
Gulf Coast Research Laboratory, Department of Coastal Sciences, University of Southern Mississippi, 703 East Beach Drive, Ocean Springs, MS 39564, USA. shuzhao.li@gmail.com
Shuzhao
S
Li
Alexander
A
Pozhitkov
Rachel A
RA
Ryan
Charles S
CS
Manning
Nancy
N
Brown-Peterson
Marius
M
Brouwer
D000818:Animals; D019295:Computational Biology / Q000379:methods; D005399:Fishes / Q000235:genetics*; D015870:Gene Expression; D020869:Gene Expression Profiling; D016678:Genome; D006801:Humans; D053858:Metabolic Networks and Pathways; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis; D012984:Software; D049490:Systems Biology; D014584:User-Computer Interface