title: Unloading intracellular calcium stores reveals regionally specific functions.
abstract: Neuronal excitability can be modulated by release of intracellular calcium but the impact of calcium store depletion on intrinsic neuronal properties is unknown. In this issue of Neuron, Narayanan et al. describe an intrinsic plasticity that is depletion induced, is regionally restricted, and may protect neurons from pathological alterations in calcium signaling.
authors.affiliation: Department of Cardiology and Pneumology, University of Goettingen, 37075 Goettingen, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Schmidt
authors.forename: Barbara E
authors.initials: BE
authors.lastname: Ehrlich