title: Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION.
authors.affiliation: Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Center for Human Experimental Therapeutics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA Analgesic Solutions, Natick, MA, USA Tufts University, Boston, MA, USA California Pacific Medical Center, San Francisco, CA, USA United States Food and Drug Administration, Bethesda, MD, USA Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Dworkin
authors.forename: Dennis C
authors.initials: DC
authors.lastname: Turk
authors.forename: Nathaniel P
authors.initials: NP
authors.lastname: Katz
authors.forename: Michael C
authors.initials: MC
authors.lastname: Rowbotham
authors.forename: Sarah
authors.initials: S
authors.lastname: Peirce-Sandner
authors.forename: Igor
authors.initials: I
authors.lastname: Cerny
authors.forename: Chekesha S
authors.initials: CS
authors.lastname: Clingman
authors.forename: Benjamin C
authors.initials: BC
authors.lastname: Eloff
authors.forename: John T
authors.initials: JT
authors.lastname: Farrar
authors.forename: Cornelia
authors.initials: C
authors.lastname: Kamp
authors.forename: Michael P
authors.initials: MP
authors.lastname: McDermott
authors.forename: Bob A
authors.initials: BA
authors.lastname: Rappaport
authors.forename: Wendy R
authors.initials: WR
authors.lastname: Sanhai
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D002908:Chronic Disease; D002986:Clinical Trials as Topic / Q000379:methods*; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D010146:Pain / Q000175:diagnosis* / Q000188:drug therapy*; D010147:Pain Measurement / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: D000700:Analgesics