title: Efficacy of exposure therapy for Japanese patients with posttraumatic stress disorder due to mixed traumatic events: A randomized controlled study.
abstract: The authors examined the efficacy of Prolonged Exposure (PE) therapy in Japanese patients with posttraumatic stress disorder (PTSD). Twenty-four patients (21 women, 3 men) with PTSD due to mixed trauma were randomly assigned to the PE group (PE with or without treatment as usual [TAU]) or the control group (TAU) only. The control group received PE after a 10-week period. Intention-to-treat analysis showed the PE group achieved significantly greater reduction than the control group at posttreatment in either PTSD or depressive symptoms. The control group had significantly decreased symptom severity after PE treatment. Symptom levels of 19 PE completers in the both groups remained low in 12-month follow-up assessments. The study's findings will promote the future dissemination and implementation of evidence-based treatment for PTSD in non-Western settings.
authors.affiliation: Division of Social Psychiatry, Tokyo Institute of Psychiatry, Tokyo Japan. asukai@prit.go.jp
authors.forename: Nozomu
authors.initials: N
authors.lastname: Asukai
authors.forename: Azusa
authors.initials: A
authors.lastname: Saito
authors.forename: Nobuko
authors.initials: N
authors.lastname: Tsuruta
authors.forename: Junji
authors.initials: J
authors.lastname: Kishimoto
authors.forename: Toru
authors.initials: T
authors.lastname: Nishikawa
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D011613:Psychotherapy / Q000379:methods*; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000453:epidemiology*; D055815:Young Adult