title: The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution.
authors.affiliation: Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093-0204, USA.
authors.forename: Alessandra S
authors.initials: AS
authors.lastname: Eustáquio
authors.forename: Sang-Jip
authors.initials: SJ
authors.lastname: Nam
authors.forename: Kevin
authors.initials: K
authors.lastname: Penn
authors.forename: Anna
authors.initials: A
authors.lastname: Lechner
authors.forename: Micheal C
authors.initials: MC
authors.lastname: Wilson
authors.forename: William
authors.initials: W
authors.lastname: Fenical
authors.forename: Paul R
authors.initials: PR
authors.lastname: Jensen
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Moore
mesh_terms: D000595:Amino Acid Sequence; D053898:Biosynthetic Pathways; D019143:Evolution, Molecular; D016680:Genome, Bacterial / Q000235:genetics*; D023281:Genomics / Q000379:methods*; D007769:Lactams / Q000378:metabolism*; D008848:Micromonosporaceae / Q000235:genetics* / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D010453:Peptide Synthases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D010802:Phylogeny
chemical_list: D007769:Lactams; C557509:salinosporamide K; D010453:Peptide Synthases; C104385:non-ribosomal peptide synthase