title: [Comparative study on the ability of adhesion and invasion of different fimA genetypes of Porphyromonas gingivalis to oral epithelial cells].
abstract: OBJECTIVE
  To compare the ability of adhesion and invasion to epithelial cells by Porphyromonas gingivalis (Pg) strains with different fimA separated from Chinese.
  
  
  METHODS
  Cultured method and antibiotic protection method were used to determine the adhesive and invasive ability of Pg with different fimA genetypes. The adhesion was observed by scanning electron microscope.
  
  
  RESULTS
  All the strains adhered and invaded to KB cells, and the adhesion rate ranged from 0.523% to 37.125% and invasive rate from 0.017% to 3.750%.The adhesive and invasive ability among different fimA genotypes showed no significant difference (P > 0.05).
  
  
  CONCLUSIONS
  There is no significant correlation between fimA genotype and ability in adhesion and invasion to KB cells.
authors.affiliation: Department of Periodontology, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Li
authors.initials: L
authors.lastname: Gao
authors.forename: Ya-fei
authors.initials: YF
authors.lastname: Wu
authors.forename: Di
authors.initials: D
authors.lastname: Miao
authors.forename: Lei
authors.initials: L
authors.lastname: Zhao
authors.forename: Shu
authors.initials: S
authors.lastname: Meng
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D001422:Bacterial Adhesion; D055113:Chronic Periodontitis / Q000382:microbiology; D004847:Epithelial Cells / Q000382:microbiology*; D036781:Fimbriae Proteins / Q000235:genetics / Q000502:physiology*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D007624:KB Cells / Q000382:microbiology / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D016966:Porphyromonas gingivalis / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*
chemical_list: C063055:fimbrillin; D036781:Fimbriae Proteins