title: [Space-occupying tumor of the temporal region with facial nerve palsy, vestibular dysfunction and hearing loss].
abstract: A 73-year-old female patient complained of right-sided facial pain, progressive loss of hearing, giddiness when changing position, a pre-auricular swelling and lack of facial expression. Clinically there was a right-sided indolent and immovable swelling approximately 7 cm in size and an incomplete ipsilateral acute peripheral facial paralysis. Magnetic resonance tomography revealed a space-occupying lesion approximately 75 mm in diameter right temporal and multilocular metastases in the pelvis, spinal column, clavicle and skull. Histology showed this to be a well to moderately differentiated adenocarcinoma with centers of positive immune response to GCDFP-24 (gross cystic disease fluid protein). The subsequent computed tomography of the thorax and mammography located the approximately 25 mm in size primary tumor in the left breast. After surgery and radiation therapy the TNM classification was a tubular adenocarcinoma of the left breast grade 2, T2N0M1 (OSS multiple osseous, BRA brain) stage IV.
authors.affiliation: Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Friedrich-Schiller-Universität, Jena, Deutschland. ellenkostka@web.de
authors.forename: E
authors.initials: E
authors.lastname: Kostka
authors.forename: O
authors.initials: O
authors.lastname: Guntinas-Lichius
authors.forename: I B
authors.initials: IB
authors.lastname: Runnebaum
authors.forename: J
authors.initials: J
authors.lastname: Füller
authors.forename: R
authors.initials: R
authors.lastname: Kalff
authors.forename: C
authors.initials: C
authors.lastname: Wittekindt
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology* / Q000628:therapy; D003937:Diagnosis, Differential; D005158:Facial Paralysis / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D013702:Temporal Lobe; D016896:Treatment Outcome; D015837:Vestibular Diseases / Q000175:diagnosis / Q000209:etiology*