title: Elastosis perforans serpiginosa in a patient with Down's syndrome.
abstract: Elastosis perforans serpiginosa is a rare, primary perforating dermatosis, frequently associated with certain genetic diseases and characterized by the transepidermal extrusion of elastic fibers. The present case report describes this dermatosis in a 19-year old female patient with Down's syndrome, who presented with asymptomatic erythematous, keratotic papules in an arciform pattern, located on her right forearm and knee, which had been present for five years. Following histopathological confirmation, treatment with cryotherapy was initiated, resulting in partial remission of the lesions.
authors.affiliation: Dermatology Department, Teaching Hospital of the Federal University of Minas Gerais, Brazil. anacarol@hc.ufmg.br
authors.forename: Ana Carolina Figueiredo
authors.initials: AC
authors.lastname: Pereira
authors.forename: Isabela Guimarães Ribeiro
authors.initials: IG
authors.lastname: Baeta
authors.forename: Sérgio Rodrigues da
authors.initials: SR
authors.lastname: Costa Júnior
authors.forename: Oswaldo Macedo
authors.initials: OM
authors.lastname: Gontijo Júnior
authors.forename: Everton Carlos Siviero do
authors.initials: EC
authors.lastname: Vale
mesh_terms: D017679:Cryotherapy; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D012871:Skin Diseases / Q000473:pathology* / Q000601:surgery; D055815:Young Adult