title: Activity of platelet hemostasis in children with spinal deformities.
abstract: An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand's factor in the vascular wall and intensification of thromboxane production in blood platelets. Activation of thromboxane formation is the main cause of platelet hyperactivity in children with scoliosis. Correction of platelet hemostasis may include pathogenetically substantiated complex of therapeutic exercises, swimming, and massage.
authors.affiliation: Kursk Institute of Social Education, Affiliated Department of the Russian State Social University, Russia.
authors.forename: I N
authors.initials: IN
authors.lastname: Medvedev
authors.forename: E V
authors.initials: EV
authors.lastname: Lapshina
authors.forename: S Yu
authors.initials: SY
authors.lastname: Zavalishina
mesh_terms: D001792:Blood Platelets / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D008297:Male; D012600:Scoliosis / Q000097:blood*; D013931:Thromboxanes / Q000096:biosynthesis; D014841:von Willebrand Factor / Q000096:biosynthesis
chemical_list: D013931:Thromboxanes; D014841:von Willebrand Factor