title: Evaluation of the expression of isoforms of stem cell factor mRNA in fetal tissues and mononuclear cells at different stages of human development.
abstract: We studied the expression of isoforms of stem cells factor mRNA forming as a result of alternative splicing. Both isoforms of stem cell factor mRNA forming as a result of alternative splicing were found in different fetal tissues. Changes in the expression of alternative isoforms of stem cell factor in peripheral blood mononuclear cells were demonstrated from the prenatal and neonatal periods to adult organism.
authors.affiliation: Research Institute of Clinical Immunology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia. sadovskayavera@ngs.ru
authors.forename: V A
authors.initials: VA
authors.lastname: Sadovskaya
authors.forename: S V
authors.initials: SV
authors.lastname: Sennikov
authors.forename: G V
authors.initials: GV
authors.lastname: Seledtsova
authors.forename: A N
authors.initials: AN
authors.lastname: Silkov
authors.forename: V A
authors.initials: VA
authors.lastname: Kozlov
mesh_terms: D000328:Adult; D017398:Alternative Splicing / Q000235:genetics / Q000502:physiology; D005260:Female; D005333:Fetus / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D020033:Protein Isoforms / Q000378:metabolism*; D019089:Stem Cell Factor / Q000378:metabolism*; D055815:Young Adult
chemical_list: D020033:Protein Isoforms; D019089:Stem Cell Factor