title: [Factors that affect time delays to fibrinolytic treatment in ischaemic stroke].
abstract: BACKGROUND
  Extending the thrombolytic therapy window in ischaemic stroke to 4.5 hours has proved to be useful and safe, but a prompt response remains a decisive factor.
  
  
  OBJECTIVE
  To analyse the factors that delay treatment.
  
  
  METHODS
  After activating the Stroke Code procedure, the consecutive cases of stroke attended in the emergency department throughout the year 2006 were recorded; data included their clinical and epidemiological features, origin, means of transport and delay times in the process.
  
  
  RESULTS
  Of the total number of patients with ischaemic stroke, 10.1% finished the emergency study with a median of 1 hour to decide to carry out treatment within 3 hours, and 13.1% of them between 3 and 4.5 hours, with a median of 2 hours and 6 minutes. For the analysis of all the variables, 498 patients were selected; 39% were admitted to hospital within the first 3 hours and 11.2% between 3 and 4.5 hours of the onset of symptoms. The use of the emergency telephone system, transport by mobile ICU or ambulance and an impaired level of consciousness, sight or, to a lesser extent, language or speech were related to shorter delay times.
  
  
  CONCLUSIONS
  The factors that depended on the actual patient, in general, did not shorten the delay time. Clinical severity, the presence of informants and activating the emergency system shortened intervention times.
authors.affiliation: Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, España. alfredo.palomino.sspa@juntadeandalucia.es
authors.forename: Alfredo
authors.initials: A
authors.lastname: Palomino-García
authors.forename: Francisco
authors.initials: F
authors.lastname: Moniche-Álvarez
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: de la Torre-Laviana
authors.forename: Aurelio
authors.initials: A
authors.lastname: Cayuela-Domínguez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Vigil
authors.forename: M Dolores
authors.initials: MD
authors.lastname: Jiménez-Hernández
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications / Q000188:drug therapy*; D004638:Emergency Treatment; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D020521:Stroke / Q000150:complications / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents