title: Preconception care for diabetic women for improving maternal and infant health.
abstract: BACKGROUND
  Infants born to mothers with pre-existing type I or type II diabetes mellitus are at greater risk of congenital anomalies, perinatal mortality and significant morbidity in the short and long term. Pregnant women with pre-existing diabetes are at greater risk of perinatal morbidity and diabetic complications. The relationship between glycaemic control and health outcomes for both mothers and infants indicates the potential for preconception care for these women to be of benefit.
  
  
  OBJECTIVE
  To assess the effects of preconception care in women with pre-existing diabetes on health outcomes for mother and baby.
  
  
  METHODS
  We searched the Cochrane Pregnancy and Childbirth Group's Trials Register was searched (30 April 2010) and reference lists of retrieved articles.
  
  
  METHODS
  Randomised, quasi-randomised and cluster-randomised trials evaluating preconception care of diabetic women.
  
  
  METHODS
  Two review authors independently conducted data extraction and quality assessment. We resolved disagreements through discussion or through a third author.
  
  
  RESULTS
  We included one trial (involving 53 women) in this review. The trial did not report on the prespecified outcomes of this review.
  
  
  CONCLUSIONS
  Little evidence is available to recommend for or against preconception care for women with pre-existing diabetes. Further large, high-quality randomised controlled trials are needed to evaluate the effect of different protocols of preconception care for women with pre-existing diabetes.
authors.affiliation: ARCH: Australian Research Centre for Health of Women and Babies, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Women's and Children's Hospital, 1st floor, Queen Victoria Building, 72 King William Road, Adelaide, South Australia, Australia, 5006.
authors.forename: Joanna
authors.initials: J
authors.lastname: Tieu
authors.forename: Philippa
authors.initials: P
authors.lastname: Middleton
authors.forename: Caroline A
authors.initials: CA
authors.lastname: Crowther
mesh_terms: D016251:CD-ROM; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000628:therapy; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D010353:Patient Education as Topic / Q000379:methods; D016742:Preconception Care / Q000379:methods*; D016032:Randomized Controlled Trials as Topic
chemical_list: D006442:Glycated Hemoglobin