title: Efficacy of a new oxygenator-integrated fat and leukocyte removal device.
abstract: We evaluated the effectiveness of a new oxygenator-integrated device for removing lipid particles and leukocytes from shed mediastinal blood in 20 patients undergoing elective cardiac surgery under cardiopulmonary bypass. Another 20 patients undergoing cardiac surgery without the device served as controls. After filtration with the RemoveLL device, lipid particles, leukocytes, and fats were significantly reduced compared to preoperative levels. In the control group, blood fats and lipid particles at the end of cardiopulmonary bypass were significantly increased compared to preoperative levels. Leukocyte counts at the end of bypass were significantly lower in patients who had the filtration device compared to the control group. Platelets counts and hematocrit changes were not significantly different between the 2 groups.
authors.affiliation: Department of Cardiovascular Surgery, Villa Maria Cecilia GVM Hospital for Care and Research, Cotignola, Lugo, RA, Italy. dellamore76@libero.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Dell'Amore
authors.forename: Alberto
authors.initials: A
authors.lastname: Tripodi
authors.forename: Andrea
authors.initials: A
authors.lastname: Cavallucci
authors.forename: Franco
authors.initials: F
authors.lastname: Guerrini
authors.forename: Barbara
authors.initials: B
authors.lastname: Ronchi
authors.forename: Silvia
authors.initials: S
authors.lastname: Zanoni
authors.forename: Mauro
authors.initials: M
authors.lastname: Lamarra
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001804:Blood Transfusion, Autologous; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D016022:Case-Control Studies; D017558:Elective Surgical Procedures; D004620:Embolism, Fat / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D004867:Equipment Design; D005260:Female; D005374:Filtration / Q000295:instrumentation*; D006400:Hematocrit; D006801:Humans; D007558:Italy; D007937:Leukapheresis / Q000295:instrumentation*; D007958:Leukocyte Count; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010106:Oxygenators; D010976:Platelet Count; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D008055:Lipids