title: Unusual case of necrotizing fasciitis caused by Vibrio cholerae O137.
abstract: We report a case of necrotizing fasciitis caused by Vibrio cholerae O137 in an immunocompromised 49-year-old man. The infection was acquired following a minor traumatic injury and exposure to seawater during the summer of 2009 in Italy. Although highly immunocompromised, the patient survived. The strain was cytotoxic, invasive, and adhesive and contained a fragment of the El Tor-like hemolysin (El Tor hlyA) gene.
authors.affiliation: Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Centro di Referenza Nazionale Controllo Microbiologico e Chimico Molluschi Bivalvi Vivi (CEREM), via Cupa di Posatora 3, 60126 Ancona, Italy. d.ottaviani@izsum.it
authors.forename: Donatella
authors.initials: D
authors.lastname: Ottaviani
authors.forename: Francesca
authors.initials: F
authors.lastname: Leoni
authors.forename: Elena
authors.initials: E
authors.lastname: Rocchegiani
authors.forename: Cristina
authors.initials: C
authors.lastname: Canonico
authors.forename: Laura
authors.initials: L
authors.lastname: Masini
authors.forename: Anna
authors.initials: A
authors.lastname: Pianetti
authors.forename: Chiara
authors.initials: C
authors.lastname: Parlani
authors.forename: Ida
authors.initials: I
authors.lastname: Luzzi
authors.forename: Iole
authors.initials: I
authors.lastname: Caola
authors.forename: Claudio
authors.initials: C
authors.lastname: Paternoster
authors.forename: Antonio
authors.initials: A
authors.lastname: Carraturo
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D002771:Cholera / Q000150:complications* / Q000175:diagnosis*; D019115:Fasciitis, Necrotizing / Q000382:microbiology* / Q000473:pathology*; D006460:Hemolysin Proteins / Q000235:genetics; D006801:Humans; D016867:Immunocompromised Host; D007558:Italy; D008297:Male; D008875:Middle Aged; D014734:Vibrio cholerae / Q000302:isolation & purification*; D037521:Virulence Factors / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D006460:Hemolysin Proteins; D037521:Virulence Factors; C084287:hlyA protein, Vibrio cholerae