title: [Study of brainstem auditory evoked potentials and its correlation with pontine volume in olivopontocerebellar atrophy].
abstract: OBJECTIVE
  To investigate the change of latency and interpeak latency of each component of BAEP (brainstem auditory evoked potential, BAEP) and its correlation with PV/PFV (pontine volume/posterior fossa volume, PV/PFV) ratio in OPCA (olivopontocerebellar atrophy, OPCA).
  
  
  METHODS
  We used Keypoint EMG/EP to determine waves I PL (peak latency, PL), III PL, V PL and I - III IPL (interpeak latency, IPL), III - V IPL, I - V IPL and used 1.5TMR 3D volume rendering software to determine PV (pontine volume, PV), CV(cerebellar volume, CV) and PFV (posterior fossa volume,PFV). Then calculated PV/PFV ratio, CV/PFV ratio and PV/ CV ratio in OPCA group and control group.
  
  
  RESULTS
  Compared with control group, in OPCA group wave IIII PL, I - III IPL were significantly elongated (P < 0.05), III - V IPL was significantly shorten (P < 0.05), PV/PFV ratio was significantly decreased (P < 0.01); there was a positive correlation between III-V IPL and PV/PFV ratio (r = 0.83, P < 0.01).
  
  
  CONCLUSIONS
  In patients with OPCA, III PL, I - III IPL of BAEP were elongated and III - V IPL of BAEP was shorten. III - V IPL became shorter when the volume of pontine decreased.
authors.affiliation: Department of Neurology, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
authors.forename: Shan-Ying
authors.initials: SY
authors.lastname: Mao
authors.forename: Jian-Zheng
authors.initials: JZ
authors.lastname: Huang
authors.forename: Mei-Ping
authors.initials: MP
authors.lastname: Ding
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009849:Olivopontocerebellar Atrophies / Q000473:pathology* / Q000503:physiopathology*; D011149:Pons / Q000473:pathology*