title: [Preoperative and postoperative serum VEGF-C levels and its clinical significance].
abstract: OBJECTIVE
  To investigate the breast cancer patients before and after vascular endothelial growth factor-C (VEGF-C) levels and their clinical significance.
  
  
  METHODS
  Using enzyme-linked immunosorbent assay (ELISA) determination of 64 cases of breast cancer patients before surgery, serum levels of VEGF-C change, while the control group of 30 patients measured serum VEGF-C levels.
  
  
  RESULTS
  Breast cancer patients a month serum levels of VEGF-C expression compare to preoperative, and its expression level decreased significantly and showed statistically significant difference (P<0.01). Metastasis of breast cancer patients before serum levels of VEGF-C expression tha those without metastasis, showed statistically significant difference (P<0.01). Breast cancer preoperative serum VEGF-C expression was significantly higher than the normal control group, showed statistically significant difference (P<0.01).
  
  
  CONCLUSIONS
  VEGF in breast cancer growth and plays an important role in the increase of serum VEGF-C show a more aggressive biological behavior.
authors.affiliation: First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
authors.forename: Song
authors.initials: S
authors.lastname: Hai-yun
authors.forename: Chen
authors.initials: C
authors.lastname: Deng-ting
authors.forename: Dong
authors.initials: D
authors.lastname: Shou-yi
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood*; D001943:Breast Neoplasms / Q000097:blood* / Q000378:metabolism / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D011379:Prognosis; D042582:Vascular Endothelial Growth Factor C / Q000097:blood*
chemical_list: D015415:Biomarkers; D042582:Vascular Endothelial Growth Factor C