title: Quality-of-life concerns in lung cancer patients.
abstract: Lung cancer is a leading cause of cancer deaths for both men and women across the world. In the past, studies on lung cancer have focused on traditional end points such as survival, disease-free survival or local control. More recently, investigators have begun to appreciate the importance of health-related quality-of-life outcomes, particularly in the setting of lung cancer. This article provides an overview of the importance, methodology, analysis and presentation of health-related quality of life in lung cancer trials, and also discusses some of the limitations and challenges of such studies.
authors.affiliation: Department of Radiation Oncology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
authors.forename: Farzan
authors.initials: F
authors.lastname: Siddiqui
authors.forename: Andre A
authors.initials: AA
authors.lastname: Konski
authors.forename: Benjamin
authors.initials: B
authors.lastname: Movsas
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods*; D018572:Disease-Free Survival; D023381:Endpoint Determination / Q000379:methods; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000523:psychology* / Q000628:therapy; D008297:Male; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D016019:Survival Analysis