title: mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging.
authors.affiliation: Cell Cycle Regulation Group, Div., Institute of Cancer Research, Department of Medicine, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. Jozefa.Gadek‐Wesierski@meduniwien.ac.at
authors.forename: Józefa
authors.initials: J
authors.lastname: Wesierska-Gadek
mesh_terms: D000818:Animals; D002453:Cell Cycle / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D048430:Cell Shape / Q000187:drug effects; D016922:Cellular Senescence / Q000187:drug effects; D004249:DNA Damage; D004317:Doxorubicin / Q000633:toxicity; D004789:Enzyme Activation; D005047:Etoposide / Q000633:toxicity; D006801:Humans; D007093:Imidazoles / Q000378:metabolism; D010879:Piperazines / Q000378:metabolism; D047428:Protein Kinase Inhibitors / Q000494:pharmacology; D044967:Serum / Q000378:metabolism; D020123:Sirolimus / Q000494:pharmacology; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013997:Time Factors; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*; D015854:Up-Regulation
chemical_list: D007093:Imidazoles; D010879:Piperazines; D047428:Protein Kinase Inhibitors; C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; C482205:nutlin 3; D005047:Etoposide; D004317:Doxorubicin; C546842:MTOR protein, human; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus