title: Nanomedicine in GI.
abstract: Recent advances in nanotechnology offer new hope for disease detection, prevention, and treatment. Nanomedicine is a rapidly evolving field wherein targeted therapeutic approaches using nanotechnology based on the pathophysiology of gastrointestinal diseases are being developed. Nanoparticle vectors capable of delivering drugs specifically and exclusively to regions of the gastrointestinal tract affected by disease for a prolonged period of time are likely to significantly reduce the side effects of existing otherwise effective treatments. This review aims at integrating various applications of the most recently developed nanomaterials that have tremendous potential for the detection and treatment of gastrointestinal diseases.
authors.affiliation: Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Hamed
authors.initials: H
authors.lastname: Laroui
authors.forename: David S
authors.initials: DS
authors.lastname: Wilson
authors.forename: Guillaume
authors.initials: G
authors.lastname: Dalmasso
authors.forename: Khalid
authors.initials: K
authors.lastname: Salaita
authors.forename: Niren
authors.initials: N
authors.lastname: Murthy
authors.forename: Shanthi V
authors.initials: SV
authors.lastname: Sitaraman
authors.forename: Didier
authors.initials: D
authors.lastname: Merlin
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods; D004337:Drug Carriers; D005762:Gastroenterology / Q000379:methods*; D005765:Gastrointestinal Agents / Q000008:administration & dosage; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D050997:Nanomedicine; D049329:Nanostructures / Q000008:administration & dosage
chemical_list: D004337:Drug Carriers; D005765:Gastrointestinal Agents