title: Lymphoepithelioma-like carcinoma involving the lacrimal gland and infiltrating the eyelids.
abstract: OBJECTIVE
  To report a case of a lymphoepithelioma-like carcinoma (LELC), which is a variant of carcinoma most commonly involving the nasopharynx and rarely occurring in a variety of sites outside its typical location.
  
  
  METHODS
  We present the case of a 79-year-old Caucasian man with LELC of the lacrimal gland undergoing surgical resection of the mass.
  
  
  RESULTS
  The patient had remained disease-free for 2 years, and then he developed homolateral metastases in latero-cervical and parotid lymph nodes, detected by computed tomography and confirmed by fine-needle aspiration biopsy. He did not receive any surgical treatment, radiotherapy, or chemotherapy because of the advanced stage of the disease and poor health condition.
  
  
  CONCLUSIONS
  This case report suggests that a diagnosis of lacrimal gland LELC makes combined early and radical therapy necessary.
authors.affiliation: Department of Ophthalmology, Catholic University of Rome, Rome, Italy. mariaantonietta.blasi@rm.unicatt.it
authors.forename: Maria Antonietta
authors.initials: MA
authors.lastname: Blasi
authors.forename: Luca
authors.initials: L
authors.lastname: Ventura
authors.forename: Michela
authors.initials: M
authors.lastname: Laguardia
authors.forename: Alessandra C
authors.initials: AC
authors.lastname: Tiberti
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Sammarco
authors.forename: Emilio
authors.initials: E
authors.lastname: Balestrazzi
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D005134:Eye Neoplasms / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000473:pathology* / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D009333:Neck; D010166:Palliative Care; D010306:Parotid Gland; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor