title: Regioselectivity-switchable hydroarylation of styrenes.
abstract: Cobalt-phosphine and cobalt-carbene catalysts have been developed for the hydroarylation of styrenes via chelation-assisted C-H bond activation, to afford branched and linear addition products, respectively, in a highly regioselective fashion. Deuterium-labeling experiments suggested a mechanism involving reversible C-H bond cleavage and olefin insertion steps and reductive elimination as the rate- and regioselectivity-determining step.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Ke
authors.initials: K
authors.lastname: Gao
authors.forename: Naohiko
authors.initials: N
authors.lastname: Yoshikai
mesh_terms: D002384:Catalysis; D003035:Cobalt / Q000737:chemistry; D006838:Hydrocarbons / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry*
chemical_list: D006838:Hydrocarbons; D013343:Styrenes; D003035:Cobalt