title: Platinum-catalyzed cyclization reaction of alkynes: synthesis of azepino[3,4-b]indol-1-ones.
abstract: Novel azepino[3,4-b]indol-1-ones were synthesized from alkyne-substituted indole-2-carboxamides by catalytic intramolecular cyclization in the presence of PtCl(2). The scope and limitations of this straightforward protocol are reported.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Str. 29a, D-18059 Rostock, Germany.
authors.forename: Marina
authors.initials: M
authors.lastname: Gruit
authors.forename: Anahit
authors.initials: A
authors.lastname: Pews-Davtyan
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001381:Azepines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*; D015394:Molecular Structure; D010984:Platinum / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001381:Azepines; D007211:Indoles; D010984:Platinum; C030374:indole