title: Influence of sex on left-sided infective endocarditis.
abstract: In many cardiovascular and infectious diseases, there are clinical and prognostic differences between men and women. The aim of this study was to compare the presentation of left-sided infective endocarditis in the two sexes. A total of 621 episodes of left-sided infective endocarditis (395 in men, 226 in women) were studied. The comparative analysis considered epidemiological, clinical, microbiological, echocardiographic and prognostic variables. Despite marked epidemiological, echocardiographic and microbiological differences between men and women, clinical characteristics, treatment approaches and outcomes (in-hospital mortality: 28% in men and 35% in women; P = .1) were similar in our patient series.
authors.affiliation: Instituto de Ciencias del Corazón, Hospital Clínico Universitario, Valladolid, España. tereseru@gmail.com
authors.forename: Teresa
authors.initials: T
authors.lastname: Sevilla
authors.forename: Ana
authors.initials: A
authors.lastname: Revilla
authors.forename: Javier
authors.initials: J
authors.lastname: López
authors.forename: Isidre
authors.initials: I
authors.lastname: Vilacosta
authors.forename: Cristina
authors.initials: C
authors.lastname: Sarriá
authors.forename: Itziar
authors.initials: I
authors.lastname: Gómez
authors.forename: Héctor
authors.initials: H
authors.lastname: García
authors.forename: José A
authors.initials: JA
authors.lastname: San Román
mesh_terms: D000328:Adult; D000368:Aged; D004562:Electrocardiography; D004697:Endocarditis, Bacterial / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012727:Sex Characteristics; D012737:Sex Factors; D016896:Treatment Outcome