title: A case of primary renal angiosarcoma.
abstract: A 78-year old man was diagnosed with a left bleeding renal cyst from CT scan results. Serial CT scans revealed the left kidney mass to be increasing in size and a new lesion in the liver. Renal cell carcinoma with liver metastasis was diagnosed and a radical nephrectomy performed. The initial pathological diagnosis was a benign chronic hematoma. However, the liver mass increased in size and multiplied, while another mass emerged in the twelfth thoracic vertebra with spinal paralysis and was immediately removed. Pathological findings for that specimen showed malignancy of stromal cell origin but low atypia. The renal specimen was re-evaluated using whole cross-section analysis and immunohistochemistry, and diagnosed as a primary renal angiosarcoma. Recombinant interleukin-2 therapy was started immediately; however, the patient died of metastatic disease 13 months after the initial operation. Although contrast imaging depicted the primary lesion as a non-specific hematoma with little focal pooling, and low-grade cytological atypia was shown pathologically, the angiosarcoma was extremely aggressive.
authors.affiliation: Department of Urology.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshida
authors.forename: Fumio
authors.initials: F
authors.lastname: Ito
authors.forename: Hayakazu
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Maeda
authors.forename: Hikaru
authors.initials: H
authors.lastname: Tomoe
authors.forename: Motohiko
authors.initials: M
authors.lastname: Aiba