title: Palladium-catalyzed allylic C-OH functionalization for efficient synthesis of functionalized allylsilanes.
abstract: A new method is described for palladium-catalyzed allylic silylation using allylic alcohols and disilanes as precursors. The reactions proceed smoothly under mild and neutral conditions, and this method is suitable for synthesis of regio- and stereodefined allylsilanes. The presented silylation reaction can be easily extended to include synthesis of allylboronates by change of the dimetallic reagent. The presented synthetic procedure offers a broad platform for the selective synthesis of functionalized allyl metal reagents, which are useful precursors in advanced organic chemistry and natural product synthesis.
authors.affiliation: Department of Organic Chemistry, Stockholm University, SE-106 91 Stockholm, Sweden.
authors.forename: Nicklas
authors.initials: N
authors.lastname: Selander
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Paasch
authors.forename: Kálmán J
authors.initials: KJ
authors.lastname: Szabó