title: [The changes of estrogen receptor (ER) and progesterone receptor (PR) mRNAs in endometrium with endometriosis].
abstract: OBJECTIVE
  To explore the expression of ER and PR mRNAs in endometrium with endometriosis.
  
  
  METHODS
  The rat model of endometriosis was established, and the expression of ER, PR mRNAs in the endometrium was examined by reverse transcription-polymerase chain reaction (RT-PCR).
  
  
  RESULTS
  The expression of ER and PR mRNAs in ectopic endometrium was significantly lower than that in eutopic and normal endometrium (P < 0.01). But no difference was observed between eutopic and normal endometrium (P > 0.05). Ratio of ER/PR mRNA in ectopic endometrium was larger than that in eutopic and in normal endometrium (P < 0.01).
  
  
  CONCLUSIONS
  The result illuminates that the increased ER plays a vital role in the onset of endometriosis.
authors.affiliation: Department of Physiology, Medical College of Jinan University, Guangzhou 510632, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zheng
authors.forename: Hong-yi
authors.initials: HY
authors.lastname: Li
authors.forename: Zi-neng
authors.initials: ZN
authors.lastname: Wang
authors.forename: Zhi-quan
authors.initials: ZQ
authors.lastname: Bai
authors.forename: Xiao-ye
authors.initials: XY
authors.lastname: Lu
mesh_terms: D000818:Animals; D004715:Endometriosis / Q000378:metabolism*; D004717:Endometrium / Q000378:metabolism*; D005260:Female; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D017207:Rats, Sprague-Dawley; D011960:Receptors, Estrogen / Q000235:genetics / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000235:genetics / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone