title: Conformational dynamics and pre-steady-state kinetics of DNA glycosylases.
abstract: Results of investigations of E. coli DNA glycosylases using pre-steady-state kinetics are considered. Special attention is given to the connection of conformational changes in the interacting biomolecules with kinetic mechanisms of the enzymatic processes.
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia. fedorova@niboch.nsc.ru
authors.forename: O S
authors.initials: OS
authors.lastname: Fedorova
authors.forename: N A
authors.initials: NA
authors.lastname: Kuznetsov
authors.forename: V V
authors.initials: VV
authors.lastname: Koval
authors.forename: D G
authors.initials: DG
authors.lastname: Knorre
mesh_terms: D045647:DNA Glycosylases / Q000737:chemistry* / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology*; D029968:Escherichia coli Proteins / Q000737:chemistry* / Q000378:metabolism*; D007700:Kinetics
chemical_list: D029968:Escherichia coli Proteins; D045647:DNA Glycosylases