title: Metachronous cancer of gallbladder and pancreas with pancreatobiliary maljunction.
abstract: Pancreaticobiliary maljunction is a congenital anomaly in which the junction between the pancreatic duct and the common bile duct is located outside the sphincter of Oddi. It is well known that pancreaticobiliary maljunction is frequently associated with carcinoma of thebiliary tract. We report a case of metachronous cancer of the gallbladder and pancreas associated with pancreaticobiliary maljunction and cystic dilatation of common bile duct in a 68-year-old Tunisian woman who underwent a cholecystectomy for acute cholecystitis. The pancreatic tumor was an adenosquamous carcinoma. Pancreaticobiliary maljunction allows for pancreatobiliary or biliopancreatic reflux which may induce biliary tract carcinoma. Few cases of multifocal cancer associated with this anomaly have been reported. The association with pancreatic carcinoma remains rare. Close attention should be given to both the biliary tract system and pancreas during the long-term follow-up of patients with pancreaticobiliary maljunction, especially after they have undergone a choledochojejunostomy.
authors.affiliation: Ahlem Lahmar, Sabah Mzabi-Regaya, Department of Pathology, Mongi Slim Hospital, 2046 Sidi-Daoued La Marsa, Tunis, Tunisia.
authors.forename: Ahlem
authors.initials: A
authors.lastname: Lahmar
authors.forename: Sadri Ben
authors.initials: SB
authors.lastname: Abid
authors.forename: Mohamed Nafaa
authors.initials: MN
authors.lastname: Arfa
authors.forename: Rached
authors.initials: R
authors.lastname: Bayar
authors.forename: Mohamed Tahar
authors.initials: MT
authors.lastname: Khalfallah
authors.forename: Sabah
authors.initials: S
authors.lastname: Mzabi-Regaya