title: MEK kinase 1: kinase domain deficiency in mice reveals a role in orchestrating the thymus-dependent immunity and TNFR family signaling.
authors.affiliation: Department of Immunology, Imperial College, 10th Floor, Commonwealth Building, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK. e.gallagher@imperial.ac.uk
authors.forename: Ewen
authors.initials: E
authors.lastname: Gallagher
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D004789:Enzyme Activation; D007109:Immunity / Q000276:immunology*; D048728:MAP Kinase Kinase Kinase 1 / Q000737:chemistry* / Q000172:deficiency / Q000378:metabolism*; D051379:Mice; D018448:Models, Immunological; D005810:Multigene Family; D017434:Protein Structure, Tertiary; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism; D018124:Receptors, Tumor Necrosis Factor / Q000378:metabolism*; D015398:Signal Transduction / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism
chemical_list: D011948:Receptors, Antigen, T-Cell; D018124:Receptors, Tumor Necrosis Factor; D044767:Ubiquitin-Protein Ligases; D048728:MAP Kinase Kinase Kinase 1