title: Highly Specific Modulators of Protein Kinase C Localization: Applications to Heart Failure.
abstract: Heart failure (HF) in which the blood supply does not match the body's needs, affects 10% of the population over 65 years old. The protein kinase C (PKC) family of kinases has a key role in normal and disease states. Here we discuss the role of PKC in HF and focus on the use of specific PKC regulators to identify the mechanism leading to this Pathology and potential leads for therapeutics.
authors.affiliation: Department of Chemical and Systems Biology, Stanford University, School of Medicine, Stanford CA 94305-5174.
authors.forename: Nir
authors.initials: N
authors.lastname: Qvit
authors.forename: Daria
authors.initials: D
authors.lastname: Mochly-Rosen