title: Coexistence of epileptic encephalopathy with continuous spike-and-wave during sleep, atypical benign partial epilepsy, and fixation-off sensitivity in two siblings.
abstract: Epileptic encephalopathy with continuous spike-and-wave during sleep is a rare age-related childhood encephalopathy characterized by neuropsychological and motor impairment, epilepsy, and typical EEG findings. Fixation-off sensitivity denotes forms of epilepsy and/or EEG abnormalities that occur during eye closure. The authors describe a girl with developmental regression, electrical status epilepticus during sleep (documented by video/EEG recording), and intermittent myoclonus. Her younger brother was diagnosed with atypical benign partial epilepsy, and his repeated video/EEG recordings unexpectedly showed fixation-off sensitivity.
authors.affiliation: Department of Pediatrics, Armed Forces Hospital, Southern Region, Khamis Mushayt, Saudi Arabia. eysaad@yahoo.co.uk
authors.forename: Imad Yassin
authors.initials: IY
authors.lastname: Saadeldin
authors.forename: Saeed M
authors.initials: SM
authors.lastname: Al-Tala
mesh_terms: D002675:Child, Preschool; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D012890:Sleep / Q000502:physiology*