title: An approach to deep brain stimulation for severe treatment-refractory Tourette syndrome: the UK perspective.
abstract: Deep brain stimulation (DBS) is an emerging therapeutic option for severe, treatment-resistant Tourette Syndrome (TS), with about 40 cases reported in the scientific literature over the last decade. Despite the production of clinical guidelines for this procedure from both European and USA centres, a number of unresolved issues still persist, mainly in relation to eligibility criteria and brain targets. The present article illustrates the UK perspective on DBS in TS and proposes consensus-based recommendations for double-blind controlled trials.
authors.affiliation: Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, UK. A.cavanna@ion.ucl.ac.uk
authors.forename: Andrea E
authors.initials: AE
authors.lastname: Cavanna
authors.forename: Clare M
authors.initials: CM
authors.lastname: Eddy
authors.forename: Rosalind
authors.initials: R
authors.lastname: Mitchell
authors.forename: Hardev
authors.initials: H
authors.lastname: Pall
authors.forename: Ian
authors.initials: I
authors.lastname: Mitchell
authors.forename: Ludvic
authors.initials: L
authors.lastname: Zrinzo
authors.forename: Tom
authors.initials: T
authors.lastname: Foltynie
authors.forename: Marjan
authors.initials: M
authors.lastname: Jahanshahi
authors.forename: Patricia
authors.initials: P
authors.lastname: Limousin
authors.forename: Marwan I
authors.initials: MI
authors.lastname: Hariz
authors.forename: Hugh
authors.initials: H
authors.lastname: Rickards
mesh_terms: D046690:Deep Brain Stimulation / Q000379:methods* / Q000639:trends; D006801:Humans; D018579:Patient Selection; D017410:Practice Guidelines as Topic / Q000592:standards; D011788:Quality of Life; D005879:Tourette Syndrome / Q000628:therapy*; D016896:Treatment Outcome; D006113:United Kingdom