title: Predicting donor asystole following withdrawal of treatment in donation after cardiac death.
abstract: Donation after cardiac death donation allows donor pool expansion. The period between withdrawal of treatment and donor a systole is extremely variable; its prolongation often results in unsuccessful organ procurement. We sought to assess a variety of donor variables to determine whether they predicted successful organ retrieval. We included all Donation after Cardiac Death (DCD) retrievals between 2002 and 2009, which were grouped as successful (n = 104) versus unsuccessful (n = 42). Factors that predicted unsuccessful organ procurement included older donor age, donor history of hypertension, higher at withdrawal, and absence of inotropic support. On multivariate analysis, mean arterial pressure retained its significance. Prediction of withdrawal-to-asystole time is complex, but our analysis suggested that donor blood pressure at withdrawal is an important predictor of whether retrieval would be successful.
authors.affiliation: Department of Transplant Surgery, St. James University Hospital, Leeds, West Yorkshire, United Kingdom. james_k_pine@hotmail.com
authors.forename: J K
authors.initials: JK
authors.lastname: Pine
authors.forename: P J
authors.initials: PJ
authors.lastname: Goldsmith
authors.forename: D M
authors.initials: DM
authors.lastname: Ridgway
authors.forename: S G
authors.initials: SG
authors.lastname: Pollard
authors.forename: K V
authors.initials: KV
authors.lastname: Menon
authors.forename: M
authors.initials: M
authors.lastname: Attia
authors.forename: N
authors.initials: N
authors.lastname: Ahmad
mesh_terms: D003643:Death; D006323:Heart Arrest; D006801:Humans; D015999:Multivariate Analysis; D012189:Retrospective Studies; D009927:Tissue and Organ Procurement