title: The aetiology and influence of age and gender on the development of advanced chronic venous insufficiency in the population of patients of semi-urban county outpatient vascular clinic in Poland.
abstract: OBJECTIVE
  To determine the aetiology and influence of age and gender on the development of advanced chronic venous insufficiency in patients of semi-urban county outpatient vascular clinic.
  
  
  METHODS
  One hundred and fourteen patients with venous ulcers were divided, based on the ultrasound examination, into group 1 or group 2, with or without post-thrombotic lesions in the deep venous system, respectively. The control group consisted of 352 patients with varicose veins and without leg ulceration. The demographic data and thrombotic risk factors were compared between the groups.
  
  
  RESULTS
  Group 1 patients (n = 109) were older than group 2 patients (n = 5) and control group patients, 64.7 versus 47.2 years (P = 0.016) and versus 53.8 years (P < 0.001), respectively. The percentage of women did not differ between group 1 and the control group, but was lower in group 2 (P = 0.01). The history of lower limb fracture or severe trauma increased the risk of post-thrombotic syndrome (PTS) in patients with venous ulcer.
  
  
  CONCLUSIONS
  In the population studied, the venous leg ulcer develops mainly due to primary varicose veins and its risk increases with age and is equal for both sexes. PTS should be suspected in younger patients with a history of severe trauma or leg fracture.
authors.affiliation: Department of General and Vascular Surgery, Poznań Medical University, Poznań, Poland. l_dzieciuchowicz@wp.pl
authors.forename: Ł
authors.initials: Ł
authors.lastname: Dzieciuchowicz
authors.forename: Z
authors.initials: Z
authors.lastname: Krasiński
authors.forename: K
authors.initials: K
authors.lastname: Motowidlo
authors.forename: M
authors.initials: M
authors.lastname: Gabriel
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D011044:Poland; D054070:Postthrombotic Syndrome / Q000175:diagnosis / Q000503:physiopathology; D012307:Risk Factors; D012737:Sex Factors; D013927:Thrombosis; D014505:Urban Population; D014689:Venous Insufficiency / Q000175:diagnosis* / Q000453:epidemiology*