title: A dual-modality probe utilizing intravascular ultrasound and optical coherence tomography for intravascular imaging applications.
abstract: We have developed a dual-modality biomedical imaging probe utilizing intravascular ultrasound (IVUS) and optical coherence tomography (OCT). It consists of an OCT probe, a miniature ultrasonic transducer and a fixed mirror. The mirror was mounted at the head of the hybrid probe 45° relative to the light and the ultrasound beams to change their propagation directions. The probe was designed to be able to cover a larger area in blood vessel by IVUS and then visualize a specific point at a much finer image resolution using OCT. To demonstrate both its feasibility and potential clinical applications, we used this ultrasound-guide OCT probe to image a rabbit aorta in vitro. The results offer convincing evidence that the complementary natures of these two modalities may yield beneficial results that could not have otherwise been obtained.
authors.forename: Hao-Chung
authors.initials: HC
authors.lastname: Yang
authors.forename: Jiechen
authors.initials: J
authors.lastname: Yin
authors.forename: Changhong
authors.initials: C
authors.lastname: Hu
authors.forename: Jonathan
authors.initials: J
authors.lastname: Cannata
authors.forename: Qifa
authors.initials: Q
authors.lastname: Zhou
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhongping
authors.initials: Z
authors.lastname: Chen
authors.forename: K Kirk
authors.initials: KK
authors.lastname: Shung
mesh_terms: D000818:Animals; D001011:Aorta / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D004867:Equipment Design; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D011817:Rabbits; D012815:Signal Processing, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods; D014159:Transducers; D018084:Ultrasonography, Interventional / Q000295:instrumentation* / Q000379:methods