title: Primary choroid plexus papilloma in the pituitary fossa: case report and literature review.
abstract: Choroid plexus papillomas are rare tumors of the central nervous system and are usually confined to the ventricular system. We illustrated a primary choroid plexus papilloma in the pituitary fossa. A 31-year-old female presented with amenorrhea and intermittent galactorrhoea, with no visual complaints in the last 2 years. Endocrine testing showed no hormone excess or deficiency of the pituitary and target glands, except for a higher prolactin level (56 ng/ml). A sharply circumscribed regular mass in the sellar region occupying the entire sella turcica and extending into the suprasellar cistern was demonstrated on MR imaging with gadolinium diethylenetriamine pentaacetic acid. The patient underwent an endonasal trans-sphenoidal approach. Complete microsurgical excision and complete preservation of the normal pituitary gland was achieved, with normal prolactin level. The histopathology showed that the lesion was a choroid plexus papilloma. Theories of the origin, the differential diagnosis, and treatment of the rare tumor are discussed.
authors.affiliation: Department of Neurosurgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, People's Republic of China. rj11118@yahoo.com
authors.forename: Liu-Guan
authors.initials: LG
authors.lastname: Bian
authors.forename: Qing-Fang
authors.initials: QF
authors.lastname: Sun
authors.forename: Hua-Cheng
authors.initials: HC
authors.lastname: Wu
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.forename: Yue-Hao
authors.initials: YH
authors.lastname: Sun
authors.forename: Jian-Kang
authors.initials: JK
authors.lastname: Shen
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D002831:Choroid Plexus / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007124:Immunoenzyme Techniques; D008279:Magnetic Resonance Imaging; D008866:Microsurgery / Q000379:methods*; D009408:Nerve Compression Syndromes / Q000175:diagnosis / Q000601:surgery; D009897:Optic Chiasm; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000601:surgery; D020288:Papilloma, Choroid Plexus / Q000175:diagnosis / Q000601:surgery*; D010901:Pituitary Function Tests; D010907:Pituitary Hormones / Q000097:blood; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery*; D011388:Prolactin / Q000097:blood; D012658:Sella Turcica / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D010907:Pituitary Hormones; D011388:Prolactin