title: Practical application of local anesthetics.
abstract: Local anesthetics are widely used in the practice of medicine, particularly within the field of interventional radiology. When used properly, these agents are safe and effective in preventing procedural pain and treating postprocedural pain. The clinician should be aware of proper dosing regimens, techniques, and applications and the methods of preventing and treating complications of systemic toxicity, allergy, and methemoglobinemia. This review provides an introduction to the pharmacology and optimal use of local anesthetics and current strategies for minimizing and managing their potential risks.
authors.affiliation: Division of Cardiothoracic Anesthesiology, The Texas A&M University College of Medicine, Scott & White Hospital, 2401 South 31st Street, Temple, TX 76508, USA. wculp@swmail.sw.org
authors.forename: William C
authors.initials: WC
authors.lastname: Culp
authors.forename: William C
authors.initials: WC
authors.lastname: Culp
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D008708:Methemoglobinemia / Q000209:etiology* / Q000517:prevention & control*; D010149:Postoperative Pain / Q000517:prevention & control*; D015641:Radiography, Interventional / Q000009:adverse effects / Q000379:methods
chemical_list: D000779:Anesthetics, Local