title: [Effects of temperature on the open-channel density of delayed rectifier K+ channels in hypothalamic neurons].
abstract: OBJECTIVE
  To observe the effect of temperature on multi-order open of delayed rectifier K+ channels in hypothalamic-neurons by cell-attached mode of patch-clamp technique.
  
  
  RESULTS
  With temperature raising, the probability of open-channel recording increased, multichannel open occurred. The density of open - channel on membrane of 32 degrees C, 37 degrees C and 39 degrees C was 0.71, 1.22 and 1.82 channels/microm2 respectively (P < 0.05).
  
  
  CONCLUSIONS
  More Ik of hypothalamus opened with temperature raising, this benefited to the body temperature regulation of neurons in hypothalamus.
authors.affiliation: Department of Thermal Environmental Medicine, the First Military Medical University, Guangzhou 510515.
authors.forename: C Q
authors.initials: CQ
authors.lastname: Cai
authors.forename: F
authors.initials: F
authors.lastname: Zou
authors.forename: B D
authors.initials: BD
authors.lastname: Luo
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D051668:Delayed Rectifier Potassium Channels / Q000502:physiology*; D007031:Hypothalamus / Q000166:cytology*; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology*; D018408:Patch-Clamp Techniques; D051381:Rats; D017207:Rats, Sprague-Dawley; D013696:Temperature
chemical_list: D051668:Delayed Rectifier Potassium Channels