title: Histomorphometry and stability analysis of early loaded implants with two different surface conditions in beagle dogs.
abstract: BACKGROUND
  Despite an improved bone reactions of Mg-incorporated implants in the animals, little yet has been carried out by the experimental investigations in functional loading conditions.
  
  
  OBJECTIVE
  This study investigated the clinical and histologic parameters of osseointegrated Mg-incorporated implants in early loading conditions.
  
  
  METHODS
  A total of 36 solid screw implants (diameter 3.75 mm, length 10 mm) were placed in the mandibles of 6 beagle dogs. Test groups included 18 Mg-incorporated implants. Turned titanium implants served as control. Gold crowns were inserted 4 weeks after implant placement and the dogs were immediately put on a food diet. Implants were observed for 10 weeks after loading. Radiographic assessments and stability tests were performed at the time of fixture installation, 2(nd) stage surgery, 4 weeks after loading, and 10 weeks after loading. Histological observations and morphometrical measurements were also performed.
  
  
  RESULTS
  Of 36 implants, 33 displayed no discernible mobility, corresponding to successful clinical function. There was no statistically significant difference between test implants and controls in marginal bone levels (P = .46) and RFA values. The mean BIC% in the Mg-implants was 54.5 ± 8.4%. The mean BIC% in the turned implant was 45.3 ± 12.2%. These differences between the Mg-implant and control implant were statistically significant (P = .005).
  
  
  CONCLUSIONS
  The anodized, Mg-incorporated implant demonstrated significantly more bone-to-implant contact (BIC) in early loading conditions.
  
  
  CONCLUSIONS
  The results of this study in beagle dogs suggest the possibility of achieving predictable stability of early loaded free-standing dental implants with Mg-incorporated surface.
authors.affiliation: Graduate Student, Department of Prosthodontics and Research Institute of Oral Science, College of Dentistry, Kangnung National University, Gangneung, Korea.
authors.forename: Dong-Seok
authors.initials: DS
authors.lastname: Kim
authors.forename: Dae-Gon
authors.initials: DG
authors.lastname: Kim
authors.forename: Chan-Jin
authors.initials: CJ
authors.lastname: Park
authors.forename: Lee-Ra
authors.initials: LR
authors.lastname: Cho