title: Alfy-dependent elimination of aggregated proteins by macroautophagy:  can there be too much of a good thing?
authors.affiliation: Department of Neurology, Columbia University, New York, NY, USA. ay46@columbia.edu
authors.forename: Ai
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Anne
authors.initials: A
authors.lastname: Simonsen
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D001343:Autophagy; D000071183:Autophagy-Related Proteins; D006367:HeLa Cells; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism*; D051379:Mice; D008954:Models, Biological; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D059748:Proteolysis; D014157:Transcription Factors / Q000737:chemistry / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D000071183:Autophagy-Related Proteins; D008565:Membrane Proteins; D014157:Transcription Factors; C499825:WDFY3 protein, human