title: Gastric cancer, Helicobacter pylori infection and other risk factors.
abstract: Gastric cancer incidence is declining. However, it is too early to consider this neoplastic disease as rare and the worldwide mortality rate still remains high. Several risk factors have been identified for non-cardia gastric cancer and primary prevention is feasible since most of the risk factors can be removed. Helicobacter pylori eradication treatment reduces but does not abolish gastric cancer risk. Indeed, gastric cancer is a multifactorial disease and removing one factor does not therefore prevent all cases. Endoscopic surveillance is still needed, especially in subjects at higher risk. The definition of high-risk patients will be the future challenge as well as identifying the best surveillance strategy for such patients.
authors.affiliation: Lorenzo Fuccio, Leonardo Henry Eusebi, Franco Bazzoli, Department of Internal Medicine and Gastroenterology, University of Bologna, 40138 Bologna, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Fuccio
authors.forename: Leonardo Henry
authors.initials: LH
authors.lastname: Eusebi
authors.forename: Franco
authors.initials: F
authors.lastname: Bazzoli