title: Severe aseptic orbital cellulitis with subtenon carboplatin for intraocular retinoblastoma.
abstract: Retinoblastoma is a rare intraocular tumor of childhood. Chemoreduction followed by laser or cryotherapy is the treatment of choice. Subtenon carboplatin injection is also an accepted treatment modality for vitreous seeds, along with systemic chemotherapy. Transient periocular edema, optic neuropathy and fibrosis of orbital tissues are the known side effects of subteneon carboplatin injection. We report a case of severe aseptic orbital cellulitis with necrosis and prolapse of the conjunctiva 48 h after the injection, which resolved well on only conservative management.
authors.affiliation: Department of Pediatric Retina and Ocular Oncology, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India. drshahpk2002@yahoo.com
authors.forename: Parag K
authors.initials: PK
authors.lastname: Shah
authors.forename: N
authors.initials: N
authors.lastname: Kalpana
authors.forename: V
authors.initials: V
authors.lastname: Narendran
authors.forename: Minu
authors.initials: M
authors.lastname: Ramakrishnan
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D016190:Carboplatin / Q000008:administration & dosage / Q000009:adverse effects*; D057785:Catheters; D005260:Female; D006801:Humans; D007223:Infant; D056965:Injections, Intraocular / Q000295:instrumentation; D054517:Orbital Cellulitis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D010781:Photography; D019572:Retinal Neoplasms / Q000188:drug therapy*; D012175:Retinoblastoma / Q000188:drug therapy*; D012720:Severity of Illness Index; D058475:Tenon Capsule; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin