title: [Endogenous thrombin potential in practical use].
abstract: An overview is given on the method and the applications of thrombin generation assays. Thrombin generation assays provide a tool which can be used to trace the entire thrombin formation and inactivation of a plasma sample. Therefore they are principally different from traditional global assays like PT and aPTT and promise new opportunities for the assessment of bleeding or thrombotic risks.
authors.affiliation: Siemens Healthcare Diagnostics Products GmbH, Emil-von-Behring-Str. 76, 35041 Marburg. matthias.wilkens@siemens.com
authors.forename: M
authors.initials: M
authors.lastname: Wilkens
mesh_terms: D000925:Anticoagulants / Q000494:pharmacology; D001780:Blood Coagulation Tests / Q000379:methods*; D006467:Hemophilia A / Q000097:blood*; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D019934:International Normalized Ratio / Q000379:methods; D011517:Prothrombin Time / Q000379:methods; D012680:Sensitivity and Specificity; D013917:Thrombin / Q000378:metabolism*; D013918:Thrombin Time / Q000379:methods; D019851:Thrombophilia / Q000097:blood*
chemical_list: D000925:Anticoagulants; D013917:Thrombin