title: [Comparison of outcomes after transradial intervention in patients of different age groups].
abstract: OBJECTIVE
  To compare the in-hospital clinical outcome of patients with coronary artery disease in different age groups [< 65 years (younger), 60 to 79 years (older), and ≥ 80 years (octogenarians)] underwent transradial intervention (TRI) so asto analyze the predictors of adverse events.
  
  
  METHODS
  From May 2004 to May 2009, a total of 16 293 patients underwent transradial intervention at our institution. The in-hospital outcome for patients in different age groups after TRI was investigated. Multivariable logistic regression analysis was performed to determinate the predictors of in-hospital major adverse cardiac events (MACE) (composed of death, myocardial infarction or target vessel revascularization).
  
  
  RESULTS
  Angiographic success rates were not different (97.5%, 97.4%, 98.1%, P > 0.05) between 3 groups. However, the rates of procedural complications became progressively higher with age group (0.8%, 1.2%, 4.0%, P < 0.01). In-hospital MACE (1.3% vs 2.2% vs 7.5%, P < 0.01) and mortality (0.1% vs 0.3% vs 2.9%, P < 0.01) increased incrementally with age group. Aad it was associated with a significant decrement of DES (92.0%, 89.6%, 57.3%, P < 0.01). The following characteristics were identified as independent multivariate predictors of in-hospital major adverse cardiac events: age ≥ 80 (OR 6.26, 95%CI: 3.33 to 11.74; P < 0.01), prior myocardial infarction (OR 2.19, 95%CI: 1.66 to 2.88; P < 0.01), left main lesion (OR 2.02, 95%CI: 1.04 to 3.91; P = 0.04), age of 65 to 79 (OR 1.83, 95%CI: 1.37 to 2.43; P < 0.01), number of implanted stents (OR 1.31, 95%CI: 1.15 to 1.50; P < 0.01), total stented length (OR 1.01, 95%CI: 1.01 to 1.02; P = 0.03), and use of DES (OR 0.59, 95%CI: 0.39 to 0.89; P = 0.01).
  
  
  CONCLUSIONS
  The younger and older patients undergoing TRI have a more favorable in-hospital outcome. However the octogenarians has a substantially higher risk of in-hospital MACE.
authors.affiliation: Coronary Heart Disease Center, Peking Union Medical College, Beijing 100037, China.
authors.forename: Sheng-wen
authors.initials: SW
authors.lastname: Liu
authors.forename: Shu-bin
authors.initials: SB
authors.lastname: Qiao
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.forename: Xue-wen
authors.initials: XW
authors.lastname: Qin
authors.forename: Min
authors.initials: M
authors.lastname: Yao
authors.forename: Jin-qing
authors.initials: JQ
authors.lastname: Yuan
authors.forename: Jue
authors.initials: J
authors.lastname: Chen
authors.forename: Hai-bo
authors.initials: HB
authors.lastname: Liu
authors.forename: Shi-jie
authors.initials: SJ
authors.lastname: You
authors.forename: Feng-huan
authors.initials: FH
authors.lastname: Hu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Dai
authors.forename: Pei
authors.initials: P
authors.lastname: Zhang
authors.forename: Wei-xian
authors.initials: WX
authors.lastname: Yang
authors.forename: Ke-Fei
authors.initials: KF
authors.lastname: Dou
authors.forename: Hong
authors.initials: H
authors.lastname: Qiu
authors.forename: Zhan
authors.initials: Z
authors.lastname: Gao
authors.forename: Chao-wei
authors.initials: CW
authors.lastname: Mu
authors.forename: Wei-hua
authors.initials: WH
authors.lastname: Ma
authors.forename: Yong-jian
authors.initials: YJ
authors.lastname: Wu
authors.forename: Jian-jun
authors.initials: JJ
authors.lastname: Li
authors.forename: Yue-jin
authors.initials: YJ
authors.lastname: Yang
authors.forename: Ji-Lin
authors.initials: JL
authors.lastname: Chen
authors.forename: Run-lin
authors.initials: RL
authors.lastname: Gao
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017534:Radial Artery; D015607:Stents; D016896:Treatment Outcome