title: Molecular genetics and genetic variation.
abstract: This chapter contains brief notes on molecular genetics, focusing on those aspects most frequently encountered in genetic epidemiology. The main sections cover the organisation and physical structure of genetic material, the mechanisms involved in transmitting genetic material from one generation to the next, and forms of genetic variation.
authors.affiliation: Department of Probability and Statistics, University of Sheffield, Sheffield, UK. md4met@sheffield.ac.uk
authors.forename: Mohammed-Elfatih
authors.initials: ME
authors.lastname: Twfieg
authors.forename: M Dawn
authors.initials: MD
authors.lastname: Teare
mesh_terms: D000818:Animals; D001483:Base Sequence; D002455:Cell Division / Q000235:genetics; D002875:Chromosomes / Q000235:genetics; D004247:DNA / Q000235:genetics; D019175:DNA Methylation / Q000235:genetics; D004261:DNA Replication / Q000235:genetics; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D008967:Molecular Biology / Q000379:methods*; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D011003:Ploidies; D011110:Polymorphism, Genetic; D014176:Protein Biosynthesis / Q000235:genetics; D011995:Recombination, Genetic / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D005819:Genetic Markers; D004247:DNA