title: Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography.
abstract: The diaminotrehalose-capped derivative of β-CD, a new member of hemispherodextrins, was synthesized and characterized by NMR spectroscopy. Its protonation constants were determined by potentiometry, and the inclusion of both the enantiomers of dansyl-phenylalanine was investigated by NMR spectroscopy. Its stereoselective properties were exploited in electrokinetic chromatography by separating four enantiomeric pairs of dansyl derivatives of amino acids.
authors.affiliation: Department of Chemical Sciences, University of Catania, Catania, Italy. ecucinotta@unict.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Cucinotta
authors.forename: Alessandro
authors.initials: A
authors.lastname: Giuffrida
authors.forename: Giulia
authors.initials: G
authors.lastname: Grasso
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Maccarrone
authors.forename: Antonino
authors.initials: A
authors.lastname: Mazzaglia
authors.forename: Marianna
authors.initials: M
authors.lastname: Messina
authors.forename: Graziella
authors.initials: G
authors.lastname: Vecchio
mesh_terms: D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013816:Thermodynamics; D014199:Trehalose / Q000138:chemical synthesis* / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D047392:beta-Cyclodextrins; D014199:Trehalose; C031215:betadex