title: Genomic sequence of an avian paramyxovirus type 1 strain isolated from Muscovy duck (Cairina moschata) in China.
abstract: The complete sequence of an avian paramyxovirus type 1 (APMV-1) strain, FP1/02, isolated from Muscovy duck in China, was determined. Sequence analysis indicated that the complete genome of strain FP1/02 contained 15,192 nucleotides (nt), following the rule of six. The genome contained an extra 6-nt insertion in the non-coding region of the NP gene when compared with other APMV-1 strains, such as strains La Sota and Beaudette C. The cleavage site of the F protein was (112)R-R-Q-K-R↓F(117), indicating that the FP1/02 strain was virulent, but the morbidity and mortality varied with the species of duck. Genotypic analysis based on the F gene revealed that APMV-1 FP1/02 was a member of genotype VII. Phylogenetic analysis showed that the FP1/02 strain shared high identity with other APMV-1 strains such as ZJ1, SF02 and NA-1 isolated from geese.
authors.affiliation: Institute of Animal Husbandry and Veterinary, Fujian Academy of Agricultural Sciences, Fuzhou 350013, Fujian, People's Republic of China.
authors.forename: S-H
authors.initials: SH
authors.lastname: Shi
authors.forename: Yu
authors.initials: Y
authors.lastname: Huang
authors.forename: S-J
authors.initials: SJ
authors.lastname: Cui
authors.forename: L-F
authors.initials: LF
authors.lastname: Cheng
authors.forename: G-H
authors.initials: GH
authors.lastname: Fu
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: C-X
authors.initials: CX
authors.lastname: Peng
authors.forename: F
authors.initials: F
authors.lastname: Lin
authors.forename: J-S
authors.initials: JS
authors.lastname: Lin
authors.forename: Jing-Liang
authors.initials: JL
authors.lastname: Su
mesh_terms: D000818:Animals; D046090:Anseriformes / Q000821:virology*; D018109:Avulavirus / Q000235:genetics* / Q000302:isolation & purification*; D002642:Chick Embryo; D002681:China; D016000:Cluster Analysis; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D009698:Nucleoproteins / Q000235:genetics; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014760:Viral Fusion Proteins / Q000235:genetics
chemical_list: D009698:Nucleoproteins; D012367:RNA, Viral; D014760:Viral Fusion Proteins