title: Alterations in the mitotic index of Allium cepa induced by infusions of Pluchea sagittalis submitted to three different cultivation systems.
abstract: We evaluated the antiproliferative effect of infusions from Pluchea sagittalis using the Allium cepa test. Infusions in three concentrations (2.5, 5, and 25 g dm-3) of leaves cultivated in three environments (in vitro, acclimatized growth chamber, and field) were used. Six onion bulbs were used for each of the eight treatments, and the mitotic index was obtained from 6000 cells per treatment. In conclusion, leaf infusions of P. sagittalis cultivated in the field have a high antiproliferative activity, as well as the cultivation system influences the antiproliferative potential.
authors.affiliation: Programa de Pós-Graduação em Ciências Biológicas, Universidade Federal de Santa Maria, Departamento de Biologia, Santa Maria, RS, Brasil.
authors.forename: Liana V
authors.initials: LV
authors.lastname: Rossato
authors.forename: Solange B
authors.initials: SB
authors.lastname: Tedesco
authors.forename: Haywood D
authors.initials: HD
authors.lastname: Laughinghouse
authors.forename: Júlia G
authors.initials: JG
authors.lastname: Farias
authors.forename: Fernando T
authors.initials: FT
authors.lastname: Nicoloso
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D049109:Cell Proliferation / Q000187:drug effects*; D008940:Mitotic Index / Q000379:methods*; D019697:Onions / Q000187:drug effects* / Q000235:genetics; D028321:Plant Preparations / Q000494:pharmacology*
chemical_list: D028321:Plant Preparations