title: Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking.
abstract: Summary Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication-induced adverse reaction, which has cutaneous, haematological and solid-organ features. It is one of the triad of life-threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.
authors.affiliation: Department of Dermatology, King's College Hospital, Denmark Hill, London, UK. sarahwalsh1@nhs.net
authors.forename: S A
authors.initials: SA
authors.lastname: Walsh
authors.forename: D
authors.initials: D
authors.lastname: Creamer
mesh_terms: D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000145:classification / Q000473:pathology; D064420:Drug-Related Side Effects and Adverse Reactions; D004802:Eosinophilia / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D012720:Severity of Illness Index; D009626:Terminology as Topic; D013997:Time Factors