title: Synthesis and biological activity of novel phenyltriazolinone derivatives.
abstract: Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, Hubei, China. qywu@mail.ccnu.edu.cn
authors.forename: Qiongyou
authors.initials: Q
authors.lastname: Wu
authors.forename: Guodong
authors.initials: G
authors.lastname: Wang
authors.forename: Shaowei
authors.initials: S
authors.lastname: Huang
authors.forename: Long
authors.initials: L
authors.lastname: Lin
authors.forename: Guangfu
authors.initials: G
authors.lastname: Yang
mesh_terms: D006540:Herbicides / Q000138:chemical synthesis* / Q000737:chemistry*; D010940:Plant Proteins / Q000037:antagonists & inhibitors*; D010944:Plants / Q000201:enzymology*; D050768:Protoporphyrinogen Oxidase / Q000037:antagonists & inhibitors*
chemical_list: D006540:Herbicides; D010940:Plant Proteins; D050768:Protoporphyrinogen Oxidase