title: Immunogenicity of single dose live attenuated hepatitis a vaccine.
abstract: A long-term immunogenicity study of a single dose live attenuated H2 strain hepatitis A vaccine is being conducted in healthy Indian children at KEM Hospital, Pune. 131 of the original 143 children vaccinated in 2004, were evaluated for anti-HAV antibodies 30 months post vaccination (2007). Seroprotective antibody levels >20 mIU/mL were demonstrated in 87.8 % subjects with an overall GMT of 92.02 mIU/mL. No hepatitis like illness was recorded in any of the subjects since vaccination.
authors.affiliation: Department of Pediatrics, KEM Hospital, Pune 411 011, India.
authors.forename: Sheila
authors.initials: S
authors.lastname: Bhave
authors.forename: Ashish
authors.initials: A
authors.lastname: Bavdekar
authors.forename: Amita
authors.initials: A
authors.lastname: Sapru
authors.forename: Seema
authors.initials: S
authors.lastname: Bawangade
authors.forename: Anand
authors.initials: A
authors.lastname: Pandit
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D006506:Hepatitis A / Q000097:blood / Q000276:immunology* / Q000517:prevention & control*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D007194:India; D008297:Male; D016036:Seroepidemiologic Studies; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D022362:Hepatitis A Vaccines; D014613:Vaccines, Attenuated