title: Synthesis and X-ray analysis of butyl and glycosyl (2-arylamino-4,4-dimethyl-6-oxocyclohex-1-ene)carbodithioates and their possible cyclization to 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives.
abstract: Variety of butyl [2-arylamino-4,4-dimethyl-6-oxo-cyclohex-1-ene]carbodithioates (3a-c), 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives (5a-c), and the glucosyl carbodithioates 6a-c as well as galactosyl carbodithioates 7a-c have been synthesized from the reaction of enaminone derivatives 1a-c with carbon disulfide followed by the alkylation with n-butyl bromide and α-d-glycosyl bromides, respectively. The amount of carbon disulfide plays a great role in the mode of reaction. The structures of the synthesized compounds were elucidated by spectral data and X-ray crystallography.
authors.affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. eelashry60@hotmail.com
authors.forename: El Sayed H
authors.initials: el SH
authors.lastname: El Ashry
authors.forename: Aly A
authors.initials: AA
authors.lastname: Aly
authors.forename: Mohammed R
authors.initials: MR
authors.lastname: Amer
authors.forename: Muhammad R
authors.initials: MR
authors.lastname: Shah
authors.forename: Seik W
authors.initials: SW
authors.lastname: Ng
mesh_terms: D018360:Crystallography, X-Ray; D003500:Cyclization; D003512:Cyclohexanones / Q000138:chemical synthesis / Q000737:chemistry*; D003514:Cyclohexylamines / Q000138:chemical synthesis / Q000737:chemistry*; D013859:Thiocarbamates / Q000138:chemical synthesis / Q000737:chemistry*; D013865:Thioglycosides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D003512:Cyclohexanones; D003514:Cyclohexylamines; D013859:Thiocarbamates; D013865:Thioglycosides