title: Listeria monocytogenes: antibiotic resistance in food production.
abstract: Listeria monocytogenes is an opportunistic human pathogen that causes listeriosis, a disease that mainly affects the immunocompromised, the elderly, infants, and pregnant women. Listeriosis has become increasingly common in the last 25 years since the first foodborne outbreak was noted. Treatment for listeriosis currently consists primarily of supportive therapy in conjunction with the use of intravenous antibiotics. Antibiotics have been commercially available for over 60 years for treatment of a myriad of clinical diseases. Bacteria resistant to antibiotics have been developing over this same period. This review seeks to elucidate the extent of antibiotic resistance in L. monocytogenes, the possible transmission mechanisms, and contributing factors to distribution of antibiotic resistance among Listeria species, and possible control strategies.
authors.affiliation: Department of Food Science and Center for Food Safety-IFSE, University of Arkansas, Fayetteville, AR 72704, USA.
authors.forename: Bwalya
authors.initials: B
authors.lastname: Lungu
authors.forename: Corliss A
authors.initials: CA
authors.lastname: O'Bryan
authors.forename: Arunachalam
authors.initials: A
authors.lastname: Muthaiyan
authors.forename: Sara R
authors.initials: SR
authors.lastname: Milillo
authors.forename: Michael G
authors.initials: MG
authors.lastname: Johnson
authors.forename: Philip G
authors.initials: PG
authors.lastname: Crandall
authors.forename: Steven C
authors.initials: SC
authors.lastname: Ricke
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005260:Female; D005506:Food Contamination / Q000517:prevention & control; D005516:Food Microbiology; D005517:Foodborne Diseases / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D016867:Immunocompromised Host; D008089:Listeria monocytogenes / Q000187:drug effects* / Q000472:pathogenicity; D008088:Listeriosis / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents