title: [Effect of Safflor injection on the intestine ultrastructure characteristics following intestine ischemia/reperfusion injury in rabbits].
abstract: OBJECTIVE
  To explore effects of Safflor (Chinese Tradional Medicine) on the intestine ultrastructure characteristics during intestine ischemia/ reperfusion injury (I/RI) in rabbits.
  
  
  METHODS
  Thirty rabbits were randomly divided into three groups: control group (group S), ischemia/reperfusion group (group I/R) and Safflor injection group (group SI). Morphological changes of intestine ischemia/reperfusion in rabbits and the protective effects of Safflor were observed under electric telescope.
  
  
  RESULTS
  The intestine ultrastructure was badly injured in group I/R. Mitochondria and intestinal mucosal cells were swellen and endoplasmic reticulum expanded, however, in the SI group the ultrastructural injury of the ischemia greatly ameliorated.
  
  
  CONCLUSIONS
  The ultrastructure injury occurrted after intestine I/RI and Safflor has protective effects on the intestine ultrastructure.
authors.affiliation: Department of Pediatric Surgery, Second Affiliated Hospital, Wenzhou 325027, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Cong-De
authors.initials: CD
authors.lastname: Chen
authors.forename: Zhong-Rong
authors.initials: ZR
authors.lastname: Li
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Chen
authors.forename: Wan-Tie
authors.initials: WT
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Fang-Yan
authors.initials: FY
authors.lastname: Wang
authors.forename: Zhou-Xi
authors.initials: ZX
authors.lastname: Fang
mesh_terms: D000818:Animals; D031187:Carthamus tinctorius / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007422:Intestines / Q000098:blood supply* / Q000648:ultrastructure*; D008297:Male; D011817:Rabbits; D015427:Reperfusion Injury / Q000517:prevention & control*
chemical_list: D004365:Drugs, Chinese Herbal