title: [Mid-term results of silver-coated Dacron graft implantation in aortic and lower extremity revascularization].
abstract: BACKGROUND
  Prosthetic graft infection or the need for reconstructive arterial surgery in septic condition is a challenging situation in vascular surgery. Recent introduction of silver coated polyester graft has meant a new therapeutic option in selecting the type of graft for revascularization. In this study we analyzed the short and midterm outcome of using silver coated grafts in aortic and lower extremity arterial reconstructions (mortality, graft occlusion, graft infection, amputation).
  
  
  METHODS
  In a single center retrospective study we implanted 42 silver coated Dacron grafts (InterGard Silver Dacron prosthesis). The indication of silver graft implantation was graft infection in 17, aorto-duodenal fistula in 7, septic condition caused by gangrene in 16 cases and in 2 cases infection was not established.
  
  
  RESULTS
  Forty silver grafts were implanted in 40 patients with diagnosed infection. The mean age was 62 years (35-81 years), 70% were men. Long term follow-up data were available in 29 patients; the mean follow-up time was 36.76 months. Early (within 30 days of surgery) death occurred in 3 and late death in 11 cases (8 and 38%). Early graft occlusion was noticed in 8 and late occlusion in 2 cases (20 and 7%). Reinfection was diagnosed in 7% of the cases in the early and the midterm period as well. Eight amputations were indicated in the early postoperative period (5 major and 3 minor) and 28% of the patients required major amputation during the follow-up.
  
  
  CONCLUSIONS
  Silver coated Dacron graft means a valuable therapeutic option with good rate of infection control in the treatment of graft infection and septic condition in the lack of autologous graft material in this high risk population.
authors.affiliation: Semmelweis Egyetem Érsebészeti Klinika 1122 Budapest Városmajor u. 68. zszeberin@yahoo.com
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Szeberin
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Münch
authors.forename: Mátyás
authors.initials: M
authors.lastname: Fehérvári
authors.forename: Gábor
authors.initials: G
authors.lastname: Bíró
authors.forename: László
authors.initials: L
authors.lastname: Entz
authors.forename: György
authors.initials: G
authors.lastname: Acsády
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000706:statistics & numerical data; D001018:Aortic Diseases / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000382:microbiology*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000379:methods*; D004378:Duodenal Diseases / Q000601:surgery; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D005500:Follow-Up Studies; D005734:Gangrene / Q000150:complications; D006083:Graft Occlusion, Vascular / Q000601:surgery; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007083:Iliac Artery / Q000601:surgery; D007412:Intestinal Fistula / Q000601:surgery; D053208:Kaplan-Meier Estimate; D035002:Lower Extremity / Q000098:blood supply* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000627:therapeutic use*; D011150:Popliteal Artery / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D018030:Silver Compounds / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome; D016157:Vascular Fistula / Q000601:surgery
chemical_list: D011093:Polyethylene Terephthalates; D018030:Silver Compounds