title: Comparative repellent activities of some plant extracts against Simulium damnosum complex.
abstract: The root and leaf extracts of four plants, Occimum gratissimum, Azadirachta indica, Pterocarpus santalinoides, and Pistia hyptis, were studied for repellent activities against the adults of Simulium damnosum sensu lato. The leaves and roots were extracted with 95% ethanol and the stocks were diluted with paraffin. The repellent activities of the extracts were investigated using human baits along the banks of River Oyan and River Ogun in southwestern Nigeria. The results showed that the root extract of O. grattissium and leaf extract of P. hyptis had highest repellent potentials with 78% and 78.1% protection against S. damnosum sensu lato, respectively, whereas the root and leaf of P. santalinoides recorded the least. Although there were significant differences in the percentage of protection of the extracts of the plants (p < 0.05), the variations in the percentage of protection of the leaf and root extracts were not statistically significant (p > 0.05). The study concludes that there exist some repellent efficacies in the extracts of the plants, most importantly O. grattissimum and P. hyptis. The plant extracts can further be developed in the prevention of man-vector contact in onchocerciasis endemic communities.
authors.affiliation: Parasitology Unit, Department of Biological Sciences, University of Agriculture, Abeokuta, Nigeria. sammywobo@gmail.com
authors.forename: Sammy O
authors.initials: SO
authors.lastname: Sam-Wobo
authors.forename: Monsuru A
authors.initials: MA
authors.lastname: Adeleke
authors.forename: Chiedu F
authors.initials: CF
authors.lastname: Mafiana
authors.forename: Olabanji H
authors.initials: OH
authors.lastname: Surakat
mesh_terms: D000328:Adult; D000818:Animals; D031601:Azadirachta / Q000187:drug effects; D006801:Humans; D007302:Insect Repellents / Q000494:pharmacology*; D008297:Male; D009549:Nigeria; D009855:Onchocerciasis / Q000517:prevention & control; D010936:Plant Extracts / Q000494:pharmacology*; D035721:Pterocarpus / Q000187:drug effects; D012843:Simuliidae / Q000187:drug effects*
chemical_list: D007302:Insect Repellents; D010936:Plant Extracts