title: Copper-catalyzed tandem reactions of 1-(2-iodoary)-2-yn-1-ones with isocyanides for the synthesis of 4-oxo-indeno[1,2-b]pyrroles.
abstract: A novel copper-catalyzed tandem reaction of 1-(2-iodoaryl)-2-yn-1-ones with isocyanides is described. The reaction is through a formal [3 + 2] cycloaddition/coupling tandem process and leads to efficient formation of 4-oxo-indeno[1,2-b]pyrroles.
authors.affiliation: Key Laboratory of Regenerative Biology and Institue of Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou Science Park, Guangzhou, 510530, China. cai_qian@gibh.ac.cn
authors.forename: Qian
authors.initials: Q
authors.lastname: Cai
authors.forename: Fengtao
authors.initials: F
authors.lastname: Zhou
authors.forename: Tianfeng
authors.initials: T
authors.lastname: Xu
authors.forename: Liangbing
authors.initials: L
authors.lastname: Fu
authors.forename: Ke
authors.initials: K
authors.lastname: Ding
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D003486:Cyanides; D006575:Heterocyclic Compounds, 3-Ring; D011758:Pyrroles; D003300:Copper