title: Renal transplantation from living related donors: a single center experience in Viet Nam.
abstract: BACKGROUND
  End-stage renal disease is a major public health problem in Viet Nam. A cooperative project between the University of Liège, Belgium, and the University of Medicine Pham Ngoc Thach, Ho Chi Minh City, Viet Nam, has permitted the establishment of an autonomous program of renal transplantation from living-related donors at the Peoples' Hospital No 115. The aim of this paper was to report the primary results of the project and to draw conclusions for the future.
  
  
  METHODS
  From January 2004 to July 2008, we performed 33 living-related renal transplantations. Mean ages of donors and recipients were 31.8 ± 9.5 and 41.6 ± 13.5 years, respectively. Laparoscopic nephrectomy was performed in 6 donors. The immunosuppressive regimen consisted of three drugs associated with induction therapy using anti-interleukin-2 receptor monoclonal antibody.
  
  
  RESULTS
  The 33 donors are in good health at follow-up. Four developed major intra- or postoperative hemorrhage necessitating transfusion, with a surgical re-exploration in 1 donor. Wound infection occurred in 2 donors. Posttransplant recipient and graft survivals at 1 versus 3 years were 82% and 73% versus 82% and 65%, respectively. Eight recipients presented 13 biopsy-proven acute rejection episodes that were reversible in 7, but 1 patient lost his graft due to an irreversible rejection. Two recipients developed cancer.
  
  
  CONCLUSIONS
  These initial results have encouraged us to continue the program of renal transplantation from living-related donors. However, they also pointed out the need to develop other donor sources.
authors.affiliation: Department of Urology and Transplantation, Peoples' Hospital No 115, Ho Chi Minh City, Viet Nam. edinhhieu@pnt.edu.vn
authors.forename: H
authors.initials: H
authors.lastname: Ledinh
authors.forename: O
authors.initials: O
authors.lastname: Detry
authors.forename: M S
authors.initials: MS
authors.lastname: Pham
authors.forename: H M
authors.initials: HM
authors.lastname: Truong
authors.forename: T P
authors.initials: TP
authors.lastname: Tran
authors.forename: P K
authors.initials: PK
authors.lastname: Nguyen
authors.forename: P D
authors.initials: PD
authors.lastname: Ta
authors.forename: T Q M
authors.initials: TQ
authors.lastname: Nguyen
authors.forename: T N N
authors.initials: TN
authors.lastname: Huynh
authors.forename: T V
authors.initials: TV
authors.lastname: Bach
authors.forename: J
authors.initials: J
authors.lastname: Joris
authors.forename: C
authors.initials: C
authors.lastname: Bonvoisin
authors.forename: A
authors.initials: A
authors.lastname: De Roover
authors.forename: P
authors.initials: P
authors.lastname: Honoré
authors.forename: J P
authors.initials: JP
authors.lastname: Squifflet
authors.forename: M
authors.initials: M
authors.lastname: Meurisse
mesh_terms: D000328:Adult; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D019520:Living Donors; D008875:Middle Aged; D014744:Vietnam