title: Intracardiac metastasis originated from chondrosarcoma.
abstract: Primary cardiac tumors are extremely rare. By comparison, metastatic involvement of the heart is over 20 times more common and has been reported in autopsy series in up to one in five patients dying of cancer. Cardiac metastasis of chondrosarcoma is absolutely not frequent. In the recent literature, a cardiac metastasis from chondrosarcoma has never been described. We report the case of an 18-year-old man with a diagnosis of cardiac metastasis that originated from a left scapular chondrosarcoma. Chondrosarcoma is a skeletal tumor with various grades of malignancy, rapidly evolving, and with a strong tendency to metastasize, with low responsiveness to chemotherapy. The onset of characteristic systemic symptoms in the late stage of the disease led to the diagnosis of a mass localized in the right atrium. Management and differential diagnosis of infective heart lesions were also very complex in a rapidly evolving life-threatening condition.
authors.affiliation: aCardiology Division Institute bDepartment of Colorectal Oncology, National Cancer Institute G. Pascale Foundation cDepartment of Public Health, Section of Pathology, Second University of Naples, Naples, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Maurea
authors.forename: Gianluca
authors.initials: G
authors.lastname: Ragone
authors.forename: Carmela
authors.initials: C
authors.lastname: Coppola
authors.forename: Antonietta
authors.initials: A
authors.lastname: Caronna
authors.forename: Carlo G
authors.initials: CG
authors.lastname: Tocchetti
authors.forename: Lucio
authors.initials: L
authors.lastname: Agozzino
authors.forename: Gaetano
authors.initials: G
authors.lastname: Apice
authors.forename: Rosario V
authors.initials: RV
authors.lastname: Iaffaioli
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000473:pathology* / Q000628:therapy; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D004452:Echocardiography; D017809:Fatal Outcome; D006325:Heart Atria / Q000473:pathology; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D012540:Scapula / Q000473:pathology*; D016896:Treatment Outcome