title: Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes.
abstract: A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me(3)SiCF(2)Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Jieming
authors.initials: J
authors.lastname: Zhu
authors.forename: Huaifeng
authors.initials: H
authors.lastname: Li
authors.forename: Kuo-Wei
authors.initials: KW
authors.lastname: Huang
authors.forename: Jinbo
authors.initials: J
authors.lastname: Hu
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D017640:Silicates / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D000475:Alkenes; D000480:Alkynes; D002712:Chlorides; D003521:Cyclopropanes; D006845:Hydrocarbons, Fluorinated; D007477:Ions; D017640:Silicates; C121084:difluorocarbene