title: [Case of angioimmunoblastic T-cell lymphoma with eosinophilia and interstitial shadows].
abstract: A 76-year-old woman was admitted because of respiratory failure with bilateral multiple interstitial shadows and mediastinal adenopathy on chest CT images. Blood examination revealed eosinophilia without leukocytosis and elevated C-reactive protein levels. Corticosteroids were administered before diagnosis because of rapid respiratory failure. Although her symptoms and pulmonary lesions disappeared with steroid therapy, they recurred 4 days later. A definitive diagnosis was not obtained until bronchofiberoptic examination. At the time of recurrence 6 months later, angioimmunoblastic T-cell lymphoma (AITL) was diagnosed with axillary lymph node biopsy. AITL is rare, and shows rapid deterioration of respiratory failure with poor prognosis. Lymph node biopsy is necessary to establish a definitive diagnosis.
authors.affiliation: National Hospital Organization, Omuta National Hospital.
authors.forename: Harutaka
authors.initials: H
authors.lastname: Omura
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Nagata
authors.forename: Kentaro
authors.initials: K
authors.lastname: Wakamatsu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Minami
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Taguchi
authors.forename: Kyoko
authors.initials: K
authors.lastname: Okamura
authors.forename: Satoko
authors.initials: S
authors.lastname: Ono
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Katahira
authors.forename: Sanae
authors.initials: S
authors.lastname: Maki
authors.forename: Takashi
authors.initials: T
authors.lastname: Akasaki
mesh_terms: D000368:Aged; D001365:Axilla; D001706:Biopsy; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications*; D005260:Female; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000473:pathology; D008482:Mediastinum; D013902:Radiography, Thoracic; D012131:Respiratory Insufficiency / Q000209:etiology; D014057:Tomography, X-Ray Computed