title: Clinical and diagnostic significance of measurement of blood activity of endopeptidases and their inhibitors in youths with mitral valve prolapse.
abstract: Activity of leukocytic elastase in young male patients with mitral valve prolapse and high (group 1) and low (group 2) adaptive capacities was increased by 57.08 and 79.14%, respectively, compared to the control (p<0.05). The leukocytic elastase/α1-proteinase inhibitor ratio in groups 1 and 2 surpassed the control value by 55.6% and by 2.16 times, respectively (p<0.05), this parameter can serve as a biochemical marker of adaptive capacity.
authors.affiliation: Rostov State Medical University, Rostov Regional Clinical Hospital, Rostov Regional Center of Cardiology and Cardiovascular Surgery, Russia. anton_chepurnenk@mail.ru
authors.forename: S A
authors.initials: SA
authors.lastname: Chepurnenko
mesh_terms: D000293:Adolescent; D010450:Endopeptidases / Q000097:blood*; D006801:Humans; D019272:Leukocyte Elastase / Q000097:blood*; D008297:Male; D008945:Mitral Valve Prolapse / Q000097:blood* / Q000201:enzymology*; D055815:Young Adult; D000511:alpha-Macroglobulins / Q000378:metabolism*
chemical_list: D000511:alpha-Macroglobulins; D010450:Endopeptidases; D019272:Leukocyte Elastase