title: [Correlation between metabolic syndrome and clinical progression in patients with benign prostatic hyperplasia].
abstract: OBJECTIVE
  To assess the correlation between metabolic syndrome and clinical progression in patients with benign prostatic hyperplasia (BPH).
  
  
  METHODS
  A total of 382 BPH patients with lower urinary tract symptoms were divided into two groups according to whether or not there was a diagnosis of metabolic syndrome (MS). MS was defined by the International Diabetes Federation (IDF) in 2005. Abdominal B-ultrasound was used to measure the total volume of prostate (TP) and its average annual growth rate was calculated. Body mass index, waist-hip ratio, blood biochemistry, blood pressure, blood glucose and other indicators were compared in these two groups of patients with regards to the clinical progression associated with BPH.
  
  
  RESULTS
  A total of 187 MS cases were found in 382 (48.59%) BPH patients. It showed a higher body mass index, high glycemia, high triglycerides, high blood pressure and high IPSS, TP and PSA levels. Also it showed a higher occurrence of surgical rate (P < 0.05); its average annual growth rate of TP was significantly higher than those without MS (1.0 vs 0.64 ml/yr, P < 0.05). TP average annual growth rate and IPSS score are found significantly correlated with blood glucose and triglyceride levels (P < 0.01).
  
  
  CONCLUSIONS
  Metabolic syndrome affects the clinical progression in patients with BPH. Clinical attention should be paid.
authors.affiliation: Department of Urology, Nanjing Medical University, Nanjing, Jiangsu 210006, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Cao
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Sun
authors.forename: Jiang-hao
authors.initials: JH
authors.lastname: Su
authors.forename: Ming-shun
authors.initials: MS
authors.lastname: Shen
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Cao
authors.forename: Rui-peng
authors.initials: RP
authors.lastname: Jia
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose; D001794:Blood Pressure; D015992:Body Mass Index; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D049629:Waist-Hip Ratio
chemical_list: D001786:Blood Glucose