title: Endemicity of human metapneumovirus subgenogroups A2 and B2 in Yamagata, Japan, between 2004 and 2009.
abstract: To clarify a longitudinal epidemiology,we isolated 280 hMPV strains from patients with acute respiratory infections in Yamagata, Japan, between 2004 and 2009.We observed that the high season for hMPV was from winter to spring (between January and May) and the low season was in the fall (around September and October). A further molecular analysis revealed that subgenogroup A2 (A2) strains were the most commonly isolated (151/280; 53.9%), followed by B2 (108/280; 38.6%) and B1 (19/280; 6.8%). Our results suggested that A2 and B2 have been endemically in circulation as the major types almost every year, whereas other subgenogroups have appeared less frequently.
authors.affiliation: Department of Microbiology, Yamagata Prefectural Institute of Public Health, Japan. mizutak@pref.yamagata.jp
authors.forename: Katsumi
authors.initials: K
authors.lastname: Mizuta
authors.forename: Chieko
authors.initials: C
authors.lastname: Abiko
authors.forename: Yoko
authors.initials: Y
authors.lastname: Aoki
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ikeda
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Itagaki
authors.forename: Noriko
authors.initials: N
authors.lastname: Katsushima
authors.forename: Yoko
authors.initials: Y
authors.lastname: Matsuzaki
authors.forename: Seiji
authors.initials: S
authors.lastname: Hongo
authors.forename: Masahiro
authors.initials: M
authors.lastname: Noda
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kimura
authors.forename: Tadayuki
authors.initials: T
authors.lastname: Ahiko
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D058872:Epidemics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007564:Japan; D029121:Metapneumovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D012141:Respiratory Tract Infections / Q000821:virology*; D012621:Seasons; D013997:Time Factors