title: Effect on the epigallocatechin gallate/epigallocatechin ratio in a green tea (Camellia sinensis L.) extract of different extraction temperatures and its effect on IgA production in mice.
abstract: We found that the epigallocatechin gallate (EGCG)/epigallocatechin (EGC) ratio in a green tea (Camellia sinensis L.) extract was affected by the extraction temperature. The EGCG/EGC ratio in the 4 °C extract was around 1:3-4, whereas in the 100 °C extract, it was around 1:0.7. Oral administration of the mixture with a high EGC ratio (1:2-3 = EGCG/EGC) resulted in greater IgA production by murine Peyer's patch cells.
authors.affiliation: National Institute of Vegetable and Tea Science, NARO, Shimada, Shizuoka, Japan. monobe@affrc.go.jp
authors.forename: Manami
authors.initials: M
authors.lastname: Monobe
authors.forename: Kaori
authors.initials: K
authors.lastname: Ema
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Tokuda
authors.forename: Mari
authors.initials: M
authors.lastname: Maeda-Yamamoto
mesh_terms: D000818:Animals; D028241:Camellia sinensis / Q000737:chemistry*; D002392:Catechin / Q000031:analogs & derivatives / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D005591:Chemical Fractionation / Q000379:methods*; D005260:Female; D007070:Immunoglobulin A / Q000276:immunology*; D007155:Immunologic Factors / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D010581:Peyer's Patches / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D013662:Tea / Q000737:chemistry*; D013696:Temperature
chemical_list: D007070:Immunoglobulin A; D007155:Immunologic Factors; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate; C057580:gallocatechol