title: Detection rate and clinical pattern of prostate cancer in Kuwait: a single-center experience.
abstract: OBJECTIVE
  To determine the detection rate and clinical pattern of prostate cancer in Kuwait.
  
  
  METHODS
  One hundred and fifty-three males suspected of having prostate cancer based on elevation of prostate-specific antigen (PSA) of more than 4 ng/ml underwent transrectal-ultrasound (TRUS)-guided needle biopsy of the prostate between January 2003 and January 2008; these formed the study group. Analysis of prostate cancer was based on age, prostate volume, PSA level and on finding any abnormality based on a combination of the diagnostic tools.
  
  
  RESULTS
  A diagnosis of prostate cancer was histologically confirmed in 42 (27.4%) patients. In those aged <55, 56-65, 66-75 and >76 years, the detection rates were 16.7, 17.6, 33.3 and 40.7%, respectively. In those with prostate volumes of >71, 51-70, 31-50 and <30 g, the detection rates were 18.2, 23.8, 30.8 and 42.9%, respectively. When the PSA levels were divided into groups of 4-10, 10-20, 20-100 and >100 ng/ml, the cancer detection rate was 11.8, 20.5, 47.1 and 83.3%, respectively. When 1, 2 and 3 of the 3 diagnostic tools (digital rectal examination, PSA, TRUS) were abnormal, the detection rate was 15.6, 27.9 and 80%, respectively.
  
  
  CONCLUSIONS
  Our data showed that the prostate cancer rate differs according to the region and that the rate was low in our center. Higher PSA and higher number of diagnostic tools with abnormal findings were associated with a higher incidence of prostate cancer.
authors.affiliation: Department of Surgery, Urology Unit, Al Amiri Hospital, Safat, Kuwait. nandarun@gmail.com
authors.forename: Arun
authors.initials: A
authors.lastname: Narayanaswamy
authors.forename: Fawzi
authors.initials: F
authors.lastname: Abul
authors.forename: T C
authors.initials: TC
authors.lastname: Mathew
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001707:Biopsy, Needle; D051517:Digital Rectal Examination / Q000592:standards*; D006801:Humans; D007730:Kuwait / Q000453:epidemiology; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000032:analysis / Q000592:standards*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000453:epidemiology; D014463:Ultrasonography / Q000379:methods / Q000592:standards*
chemical_list: D017430:Prostate-Specific Antigen