title: Longitudinal wall motion of the common carotid artery can be assessed by velocity vector imaging.
abstract: Velocity vector imaging (VVI) is novel ultrasound image analysis software, enabling simultaneous evaluation of longitudinal and radial tissue motion. This study aimed to investigate the possible usefulness of VVI in evaluating the longitudinal vessel wall movement of the common carotid artery (CCA). Sixteen healthy volunteers and 16 patients with established coronary artery disease (CAD) were included in the study. CCA was scanned and standard B-mode ultrasound images were analysed off-line with VVI. In healthy volunteers, total longitudinal displacements (tLoD) of the right and left CCA were similar, as were the movements of the near- and far wall of the right CCA. The CAD group showed significantly lower tLoD compared to the healthy volunteers (0·543 ± 0·394 versus 0·112 ± 0·074, P<0·0001). VVI is a highly feasible technique in assessing longitudinal CCA wall motion, which may be of potential relevance as a novel vascular biomarker.
authors.affiliation: The Department of Clinical Physiology, Sahlgrenska University Hospital, Göteborg, Sweden. sara.svedlund@gu.se
authors.forename: Sara
authors.initials: S
authors.lastname: Svedlund
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Gan
mesh_terms: D000328:Adult; D000368:Aged; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000473:pathology; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D003331:Coronary Vessels / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012984:Software; D014463:Ultrasonography; D055815:Young Adult