title: Prevalence of suspected hypertrophic cardiomyopathy or left ventricular hypertrophy based on race and gender in teenagers using screening echocardiography.
abstract: BACKGROUND
  The goal of this study was to evaluate the prevalence of suspected hypertrophic cardiomyopathy (HCM) in a population of teenagers undergoing screening echocardiography for the detection of HCM.
  
  
  METHODS
  The Anthony Bates Foundation performs screening echocardiography for the prevention of sudden death. A total of 2,066 students were studied between the ages of 13 to 19 years. Suspected HCM was defined as any wall thickness ≥ 15 mm. LVH was defined as wall thickness ≥ 13 mm
  
  
  RESULTS
  Prevalence of suspected HCM was 0.7% (14/2066). After adjusting for hypertension (HTN), the total prevalence was 0.5% (8/1457). In a subgroup analysis, 551 teenagers with documented race and LV wall thickness were identified between the ages of 13-19 years. African American teenagers [6% (3/50)] had higher prevalence of suspected HCM [0.8% (4/501), OR 7.93, CI 1.72-36.49, p = 0.002]. After multivariate adjustment for age, gender, BMI and HTN (systolic BP >140 and diastolic BP of > 90), African American race remained independently associated with suspected HCM (OR 4.89, CI 1.24-39.62, p = 0.02).
  
  
  CONCLUSIONS
  The prevalence of suspected HCM in young teenagers is approximately 0.2%. This prevalence appears to be higher in African Americans. However, due to small number of African Americans in our population, our result needs to be confirmed in larger trials.
authors.affiliation: Sarver Heart Center, University of Arizona College of Medicine, Department of Medicine, Division of Cardiology, 1501 N Campbell Avenue, Tucson, Arizona, USA. rmova@aol.com
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Movahed
authors.forename: Deborah
authors.initials: D
authors.lastname: Strootman
authors.forename: Sharon
authors.initials: S
authors.lastname: Bates
authors.forename: Sudhakar
authors.initials: S
authors.lastname: Sattur
mesh_terms: D000293:Adolescent; D001130:Arizona / Q000453:epidemiology; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015897:Comorbidity; D004452:Echocardiography / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D008297:Male; D008403:Mass Screening; D015995:Prevalence; D044469:Racial Groups / Q000706:statistics & numerical data*; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D055815:Young Adult