title: Peritoneal seeding from appendiceal carcinoma: A case report and review of the literature.
abstract: Non-carcinoid appendiceal malignancies are rare entities, representing less than 0.5% of all gastrointestinal malignancies. Because of their rarity and particular biological behavior, a substantial number of patients affected by these neoplasms do not receive appropriate surgical resection. In this report, we describe a rare case of primary signet-ring cell carcinoma of the appendix with peritoneal seeding which occurred in a 40-year old man admitted at the Emergency Surgery Department with the clinical suspicion of acute appendicitis. After a surgical debulking and right hemicolectomy, the patient had systemic chemotherapy according to FOLFOX protocol. After completion of the latter, the patient underwent cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy. This report offers a brief review of the literature and suggests an algorithm for the management of non-carcinoid appendiceal tumors with peritoneal dissemination.
authors.affiliation: Valentina R Bertuzzo, Federico Coccolini, Antonio D Pinna, Department of General, Emergency and Transplant Surgery, Sant'Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy.
authors.forename: Valentina R
authors.initials: VR
authors.lastname: Bertuzzo
authors.forename: Federico
authors.initials: F
authors.lastname: Coccolini
authors.forename: Antonio D
authors.initials: AD
authors.lastname: Pinna