title: Total synthesis of cyanolide A.
abstract: The total synthesis of cyanolide A has been achieved in 14 steps from commercially available (S)-2-ethyloxirane, exploiting the palladium-catalyzed intramolecular alkoxycarbonylation as the key step to construct the tetrasubstituted cis-tetrahydropyran ring with high stereoselectivity.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
authors.forename: Xingang
authors.initials: X
authors.lastname: Xie
authors.forename: Peng
authors.initials: P
authors.lastname: Jing
authors.forename: Gaoyuan
authors.initials: G
authors.lastname: Zhao
authors.forename: Jiyue
authors.initials: J
authors.lastname: Zheng
authors.forename: Changgui
authors.initials: C
authors.lastname: Zhao
authors.forename: Xuegong
authors.initials: X
authors.lastname: She
mesh_terms: D002384:Catalysis; D018942:Macrolides / Q000138:chemical synthesis*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D018942:Macrolides; C548188:cyanolide A; D010165:Palladium