title: Diagnosis, management, and pathogenesis of TTP/HUS in an HIV positive patient.
abstract: An atypical presentation of HUS/TTP in an HIV positive adult with a prodrome of bloody diarrhea and lack of neurological deficits makes atypical HUS the likely etiology. This case demonstrates the differing treatment modalities for HUS and TTP given the atypical presentation and a discussion of the pathogenesis.
authors.affiliation: Christiana Care Health System in Newark, Del, USA.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Burke
authors.forename: David
authors.initials: D
authors.lastname: Aljadir
authors.forename: Tuhina
authors.initials: T
authors.lastname: Raman
mesh_terms: D051722:ADAM Proteins / Q000172:deficiency; D000328:Adult; D000367:Age Factors; D000743:Anemia, Hemolytic / Q000175:diagnosis / Q000209:etiology; D000818:Animals; D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D017242:Complement Factor H / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D005938:Glucocorticoids / Q000627:therapeutic use; D006679:HIV Seropositivity / Q000150:complications* / Q000276:immunology; D006461:Hemolysis; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000235:genetics / Q000401:mortality; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D008297:Male; D010951:Plasma Exchange; D010956:Plasmapheresis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000209:etiology; D012756:Sheep; D016896:Treatment Outcome; D014841:von Willebrand Factor / Q000276:immunology
chemical_list: D005938:Glucocorticoids; D014841:von Willebrand Factor; D017242:Complement Factor H; D051722:ADAM Proteins