title: Genetic variability of spermatozoon production and morphology in laboratory mice.
abstract: Strain-specific differences in the production of spermatozoa and incidence of atypical spermatogenesis were studied in males of 7 inbred strains: BALB/cLac, PT, CBA/Lac, DD, A/He, C57Bl/6J, and YT. The results attest to significant genetic variability of the counts of epididymal spermatozoa (differing by more than 1.5-2 times) and incidence of abnormal spermatozoon heads (differing by more than 4 times). However, the strain-specific variability of both signs was not coordinated. The selected set of inbred mouse strains can become a prospective genetic model for studies of physiological and hereditary nature of spermatogenesis variability.
authors.affiliation: Laboratory of Endocrinological Genetics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia. losadch@bionet.nsc.ru
authors.forename: L V
authors.initials: LV
authors.lastname: Osadchuk
authors.forename: A V
authors.initials: AV
authors.lastname: Osadchuk
mesh_terms: D000818:Animals; D005260:Female; D014644:Genetic Variation; D008297:Male; D051379:Mice; D013094:Spermatozoa / Q000502:physiology*