title: Dual grafts live donor liver transplantation for acute-on-chronic hepatitis B liver failure.
abstract: OBJECTIVE
  This study reports the preliminary experience of dual grafts living donor liver transplantation (LDLT) for patients with acute-on-chronic liver failure (AoCLF) caused by hepatitis B.
  
  
  METHODS
  Two patients who demonstrated acute-on-chronic hepatitis B liver failure and portal hypertension with Model for End-Stage Liver Disease (MELD) scores of 42 and 37, respectively, underwent dual LDLT grafts including one right lobe without a middle hepatic vein and one left lobe because the graft-to-recipient body weight ratio of the right lobe grafts were 0.53% and 0.66%. The donors and the recipients have been followed for over 1 year.
  
  
  RESULTS
  Mortality and operative complications were not observed in the donors or recipients. At present, the donors and recipients have returned to their daily routine. No prisoners or organs from prisoners were used to obtain these data.
  
  
  CONCLUSIONS
  Dual LDLT grafts including one right lobe without the middle hepatic vein and one left lobe may be a possible therapeutic option for subjects with acute-on-chronic hepatitis B-induced liver failure.
authors.affiliation: Liver Transplantation Center and Hepato-Bilio-Pancreatology Department, West China Hospital, West China Medical School of Sichuan University, Chengdu, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: Y
authors.initials: Y
authors.lastname: Zeng
authors.forename: T F
authors.initials: TF
authors.lastname: Wen
authors.forename: S
authors.initials: S
authors.lastname: Gong
authors.forename: J C
authors.initials: JC
authors.lastname: Zhao
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: W T
authors.initials: WT
authors.lastname: Wang
authors.forename: M Q
authors.initials: MQ
authors.lastname: Xu
authors.forename: J
authors.initials: J
authors.lastname: Yang
authors.forename: H
authors.initials: H
authors.lastname: Wu
authors.forename: L N
authors.initials: LN
authors.lastname: Yan
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D006509:Hepatitis B / Q000503:physiopathology / Q000517:prevention & control / Q000601:surgery*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016031:Liver Transplantation; D019520:Living Donors
chemical_list: D007166:Immunosuppressive Agents