title: The relationship between clinical findings and esophageal injury severity in children with corrosive agent ingestion.
abstract: BACKGROUND
  The aim of the study was to investigate the indicators of corrosive esophageal injury (EI) severity in children.
  
  
  METHODS
  We retrospectively reviewed data from children who accidentally ingested corrosive substance and underwent endoscopic evaluation over a one-year period. A total of 134 consecutive children with corrosive agent ingestion who underwent diagnostic endoscopy (74 boys, 60 girls) were included in this study. Patients were divided into two groups as low-grade and high-grade EI. Statistical differences and predictive values of common signs and symptoms and white blood cell (WBC) count of patients with low- and high-grade EI were analyzed.
  
  
  RESULTS
  The majority of patients (70%) were asymptomatic at the initial examination. We found that drooling saliva and oral lesions were significantly more frequent in high-grade injury (p<0.05). Mean WBC count in the high-grade EI group was significantly higher than in the low-grade EI group (p=0.000). Sensitivity, specificity and predictive values of clinical findings in children were analyzed; none of them was shown to be valuable for estimating EI severity. WBC count was sensitive, but it is not a good predictor.
  
  
  CONCLUSIONS
  Our study demonstrated the relationship between clinical findings and corrosive EI severity in children with accidental corrosive ingestion, but direct visualization of the esophagus is required for definitive diagnosis.
authors.affiliation: Department of Pediatric Surgery, Tepecik Education and Research Hospital, İzmir, Turkey. kayamete@yahoo.com
authors.forename: Mete
authors.initials: M
authors.lastname: Kaya
authors.forename: Tunç
authors.initials: T
authors.lastname: Ozdemir
authors.forename: Ali
authors.initials: A
authors.lastname: Sayan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Arıkan
mesh_terms: D000284:Administration, Oral; D002057:Burns, Chemical / Q000150:complications*; D002424:Caustics / Q000008:administration & dosage / Q000633:toxicity*; D002648:Child; D002675:Child, Preschool; D004935:Esophageal Diseases / Q000097:blood / Q000209:etiology*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D012189:Retrospective Studies; D012463:Saliva / Q000378:metabolism; D014947:Wounds and Injuries / Q000097:blood / Q000209:etiology*
chemical_list: D002424:Caustics