title: In vitro fertilization surrogacy in rare coexisting Mayer-Rokitansky-Kuster-Hauser syndrome and triple X karyotype.
abstract: OBJECTIVE
  To report the responses to IVF surrogacy attempts in a female with a heretofore never described combination of Mayer-Rokitansky-Kuster-Hauser (MRHK) syndrome and triple X karyotype.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Reproductive unit of a university-affiliated medical center.
  
  
  METHODS
  A 29-year-old female diagnosed as having both MRHK syndrome and a triple X (47XXX) karyotype.
  
  
  METHODS
  Five cycles of IVF surrogacy.
  
  
  METHODS
  Recovery of oocytes after controlled ovarian stimulation.
  
  
  RESULTS
  A maximum of five oocytes were retrieved by percutaneous abdominal aspiration of a single subcostal left ovary. After five unsuccessful IVF trials due to low ovarian response attributed to her coexisting MRHK syndrome and triple X karyotype, the patient's choice was oocyte donation.
  
  
  CONCLUSIONS
  An abnormal karyotype can coexist with MRKH syndrome, albeit very rarely, and probably accounts for a low ovarian response to attempts to achieve IVF surrogacy.
authors.affiliation: The IVF Unit, Assaf Harofeh Medical Center, Zerifin, Israel. araziel@asaf.health.gov.il
authors.forename: Arieh
authors.initials: A
authors.lastname: Raziel
authors.forename: Shevach
authors.initials: S
authors.lastname: Friedler
authors.forename: Yariv
authors.initials: Y
authors.lastname: Gidoni
authors.forename: Ido
authors.initials: I
authors.lastname: Ben-ami
authors.forename: Deborah
authors.initials: D
authors.lastname: Strassburger
authors.forename: Raphael
authors.initials: R
authors.lastname: Ron-El
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000150:complications / Q000628:therapy; D000015:Abnormalities, Multiple / Q000628:therapy; D000328:Adult; D041321:Chromosomes, Human, X; D000013:Congenital Abnormalities; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D007621:Karyotyping; D007668:Kidney / Q000002:abnormalities; D009095:Mullerian Ducts / Q000002:abnormalities; D011247:Pregnancy; D012729:Sex Chromosome Aberrations; D058533:Sex Chromosome Disorders of Sex Development / Q000150:complications / Q000628:therapy; D019170:Somites / Q000002:abnormalities; D013131:Spine / Q000002:abnormalities; D013533:Gestational Carriers; D014314:Trisomy; D014599:Uterus / Q000002:abnormalities; D014621:Vagina / Q000002:abnormalities