title: Obesity and obesity-related comorbidities in a Canadian First Nation population.
abstract: BACKGROUND
  Rates of obesity are higher among Canada's Aboriginal First Nations populations than among non-First Nations populations. We studied obesity and obesity-related illness in a Manitoba First Nation community.
  
  
  METHODS
  We conducted a screening study of diabetes and diabetes complications in 2003, from which we drew a representative sample of Manitoba First Nations adults (N = 483). We assessed chronic disease and chronic disease risk factors.
  
  
  RESULTS
  Prevalence of obesity and associated comorbidities was higher among women than men. By using multivariate analysis, we found that factors significantly associated with obesity among women were diastolic blood pressure, insulin resistance, and employment status. Among men, factors were age, apolipoprotein A1 level, apolipoprotein B level, and insulin resistance. Seventy-five percent of study participants had at least 1 of the following conditions: obesity, dyslipidemia, hypertension, or diabetes. Comorbidity was high even among the youngest age groups; 22% of men and 43% of women aged 18 to 29 had 2 or more chronic conditions. Twenty-two percent of participants had undiagnosed hypertension. Participants with undiagnosed hypertension had significantly more chronic conditions and were more likely to have microalbuminuria than were those without hypertension. The number of chronic conditions was not significantly different for participants with newly diagnosed hypertension than for those with previously diagnosed hypertension.
  
  
  CONCLUSIONS
  The prevalence of obesity and other chronic conditions in the study community is high, especially considering the number of young people. Community-based interventions are being undertaken to reduce the excessive rate of illness.
authors.affiliation: University of Manitoba, Department of Community Health Sciences, S113 Medical Services Bldg, 750 Bannatyne Ave, Winnipeg, MB Canada. brucesg@cc.umanitoba.ca
authors.forename: Sharon G
authors.initials: SG
authors.lastname: Bruce
authors.forename: Natalie D
authors.initials: ND
authors.lastname: Riediger
authors.forename: James M
authors.initials: JM
authors.lastname: Zacharias
authors.forename: T Kue
authors.initials: TK
authors.lastname: Young
mesh_terms: D000293:Adolescent; D000328:Adult; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology; D050171:Dyslipidemias / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology; D007198:Indians, North American; D008297:Male; D008350:Manitoba / Q000453:epidemiology / Q000208:ethnology; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000453:epidemiology*; D055815:Young Adult