title: Increased lysine content in rice grains by over-accumulation of BiP in the endosperm.
abstract: Over-accumulation of lysine-rich binding protein (BiP) in the rice endosperm caused strong endoplasmic reticulum (ER) stress and reduced seed storage proteins, resulting in a relative increase in nutritionally balanced non-seed storage proteins. We show that transgenic rice with over-accumulated BiP was a high-lysine rice germplasm and that the over-accumulation of BiP in the endosperm offered a unique strategy to improve the lysine content of cereal grains.
authors.affiliation: Transgenic Crop Research and Development Center, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan.
authors.forename: Taiji
authors.initials: T
authors.lastname: Kawakatsu
authors.forename: Shuyi
authors.initials: S
authors.lastname: Wang
authors.forename: Yuhya
authors.initials: Y
authors.lastname: Wakasa
authors.forename: Fumio
authors.initials: F
authors.lastname: Takaiwa
mesh_terms: D056625:Endosperm / Q000235:genetics / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism*; D018832:Molecular Chaperones / Q000235:genetics / Q000378:metabolism*; D012275:Oryza / Q000235:genetics / Q000378:metabolism*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified; D015202:Protein Engineering / Q000379:methods*
chemical_list: D018832:Molecular Chaperones; D010940:Plant Proteins; D008239:Lysine