title: The linear ubiquitin chain assembly complex forms part of the TNF-R1 signalling complex and is required for effective TNF-induced gene induction and prevents TNF-induced apoptosis.
authors.affiliation: Tumour Immunology Unit, Department of Medicine, Imperial College London, UK.
authors.forename: Christoph H
authors.initials: CH
authors.lastname: Emmerich
authors.forename: Anna C
authors.initials: AC
authors.lastname: Schmukle
authors.forename: Tobias L
authors.initials: TL
authors.lastname: Haas
authors.forename: Björn
authors.initials: B
authors.lastname: Gerlach
authors.forename: Stefanie M
authors.initials: SM
authors.lastname: Cordier
authors.forename: Eva
authors.initials: E
authors.lastname: Rieser
authors.forename: Henning
authors.initials: H
authors.lastname: Walczak
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D006801:Humans; D051379:Mice; D008954:Models, Biological; D046912:Multiprotein Complexes / Q000378:metabolism*; D025821:Polyubiquitin / Q000378:metabolism; D011485:Protein Binding; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000378:metabolism*; D015398:Signal Transduction; D015533:Transcriptional Activation; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*; D025801:Ubiquitin / Q000378:metabolism*
chemical_list: D046912:Multiprotein Complexes; D047888:Receptors, Tumor Necrosis Factor, Type I; D014409:Tumor Necrosis Factor-alpha; D025801:Ubiquitin; D025821:Polyubiquitin