title: Does DNA methylation in the promoter region of the ATXN3 gene modify age at onset in MJD (SCA3) patients?
authors.forename: V E
authors.initials: VE
authors.lastname: Emmel
authors.forename: I
authors.initials: I
authors.lastname: Alonso
authors.forename: L B
authors.initials: LB
authors.lastname: Jardim
authors.forename: M L
authors.initials: ML
authors.lastname: Saraiva-Pereira
authors.forename: J
authors.initials: J
authors.lastname: Sequeiros
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000067699:Ataxin-3; D002648:Child; D019175:DNA Methylation; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D017827:Machado-Joseph Disease / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000378:metabolism*; D009687:Nuclear Proteins / Q000235:genetics* / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D012097:Repressor Proteins / Q000235:genetics* / Q000378:metabolism*; D017421:Sequence Analysis; D019680:Trinucleotide Repeat Expansion; D055815:Young Adult
chemical_list: D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D012097:Repressor Proteins; C092341:ATXN3 protein, human; D000067699:Ataxin-3