title: Prevention of neonatal herpes.
abstract: Neonatal herpes can occur when the neonate is exposed to herpes simplex virus in the maternal genital tract during labour. Attack rates are highest when the mother has a newly acquired infection and, therefore, does not have antibodies to protect the neonate. Even with early therapy, there is significant morbidity and mortality associated with neonatal herpes, suggesting that preventing neonatal herpes simplex virus exposure or early recognition of exposure is important. The incidence of neonatal herpes has not declined despite national guidelines for prevention. This suggests that the prevention guidelines need to be re-addressed.
authors.affiliation: Department of Obstetrics and Gynecology, University of Washington, Seattle, 98195-6460, USA. cgardel@u.washington.edu
authors.forename: C
authors.initials: C
authors.lastname: Gardella
authors.forename: Z
authors.initials: Z
authors.lastname: Brown
mesh_terms: D005260:Female; D006561:Herpes Simplex / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D018259:Herpesvirus 1, Human; D018258:Herpesvirus 2, Human; D006801:Humans; D007231:Infant, Newborn; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors