title: Synthetic circuits, devices and modules.
abstract: The aim of synthetic biology is to design artificial biological systems for novel applications. From an engineering perspective, construction of biological systems of defined functionality in a hierarchical way is fundamental to this emerging field. Here, we highlight some current advances on design of several basic building blocks in synthetic biology including the artificial gene control elements, synthetic circuits and their assemblies into devices and modules. Such engineered basic building blocks largely expand the synthetic toolbox and contribute to our understanding of the underlying design principles of living cells.
authors.affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Taijiao
authors.initials: T
authors.lastname: Jiang
mesh_terms: D053263:Gene Regulatory Networks; D005813:Genes, Synthetic; D005818:Genetic Engineering / Q000379:methods*; D008954:Models, Biological; D011506:Proteins / Q000737:chemistry; D012045:Regulatory Sequences, Nucleic Acid; D058615:Synthetic Biology / Q000379:methods*
chemical_list: D011506:Proteins