title: Innovative technique in nonmuscle invasive bladder cancer-bipolar plasma vaporization.
abstract: OBJECTIVE
  To evaluate the efficacy and safety of a newly introduced endoscopic technique in the treatment of nonmuscle-invasive bladder tumors (NMIBT), the bipolar plasma vaporization of bladder tumors (BPV-BT), and to compare it with monopolar transurethral resection of bladder tumors (TURBT).
  
  
  METHODS
  A total of 120 patients with at least one bladder tumor larger than 3 cm were enrolled in the study and randomized for BPV-BT and TURBT. Resection biopsy followed by tumor plasma vaporization and biopsies of the tumoral bed were performed in the 60 cases of the BPV-BT arm. All NMIBT patients underwent monopolar Re-TURBT 4 weeks after the initial procedure.
  
  
  RESULTS
  The mean operative time and postoperative hemoglobin decrease were significantly improved for BPV-BT compared with TURBT (21.4 minutes vs 32.7 minutes and 0.3 g/dL vs 0.9 g/dL). The perioperative complications were more frequent in the TURBT arm. The mean catheterization period and hospital stay were significantly shorter in the BPV-BT series (2.5 vs 3.5 days and 3.5 vs 4.5 days). During follow-up, the overall residual tumors' rate at Re-TURBT was 9.3% in the BPVBT group vs 20.8% in the TURBT group. Primary site recurrences occurred in 7.4% vs 17% of the cases, whereas in patients with initial multiple tumors, the recurrence rate was 9.7% vs 25%.
  
  
  CONCLUSIONS
  BPV-BT seems to represent a promising endoscopic treatment alternative for NMIBT patients, with good efficacy, reduced morbidity, fast postoperative recovery, and significantly decreased residual tumors' rate by compared with TURBT.
authors.affiliation: Saint John Emergency Clinical Hospital, Department of Urology, Bucharest, Romania. geavlete@gmail.com
authors.forename: Bogdan
authors.initials: B
authors.lastname: Geavlete
authors.forename: Razvan
authors.initials: R
authors.lastname: Multescu
authors.forename: Dragos
authors.initials: D
authors.lastname: Georgescu
authors.forename: Marian
authors.initials: M
authors.lastname: Jecu
authors.forename: Mihai
authors.initials: M
authors.lastname: Dragutescu
authors.forename: Petrisor
authors.initials: P
authors.lastname: Geavlete
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011446:Prospective Studies; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods*; D014835:Volatilization