title: Ethanol sensitizes the nervous system of Caenorhabditis elegans nematode to heat stress.
abstract: Ethanol sensitizes the nervous system of C. elegans to heat stress, which manifested in exacerbation of locomotion disturbances induced by exposure to constant temperature 36°C. Adaptation of C. elegans to high temperature by heat shock (1 h at 32°C and 1 h at 18°C) or two-hour exposure at 30°C resulted considerably reduced sensitivity of the nervous system to the negative effects of ethanol under conditions of heat stress.
authors.affiliation: Institute of Ecology of Natural Systems, Academy of Sciences of Tatarstan, Kazan, Russia.
authors.forename: M Kh
authors.initials: MKh
authors.lastname: Gainutdinov
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Timoshenko
authors.forename: A M
authors.initials: AM
authors.lastname: Petrov
authors.forename: T M
authors.initials: TM
authors.lastname: Gainutdinov
authors.forename: T B
authors.initials: TB
authors.lastname: Kalinnikova
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000187:drug effects* / Q000502:physiology*; D000431:Ethanol / Q000494:pharmacology*; D006358:Hot Temperature; D008124:Locomotion / Q000187:drug effects / Q000502:physiology; D009420:Nervous System / Q000187:drug effects*; D013696:Temperature
chemical_list: D000431:Ethanol