title: [Effects of intermittent hypoxia on long-term potentiation in hippocampal dentate gyrus of rat].
abstract: OBJECTIVE
  To investigate the effects of intermittent hypoxia on the hippocampal synaptic plasticity in rat.
  
  
  METHODS
  The evoked potentials were recorded extracellularly, then the LTP were induced by tetanic stimulation in rat hippocampal dentate gyrus.
  
  
  RESULTS
  Compared with control group, the amplitude of LTP was significantly reduced in hippocampus of rat treated with intermittent hypoxia.
  
  
  CONCLUSIONS
  The present results suggest that the hippocampal synaptic plasticity could be decreased by the treated of intermittent hypoxia.
authors.affiliation: Department of Anesthesiology, Union Hospital, Tongji Medical University, Wuhan 430022.
authors.forename: X R
authors.initials: XR
authors.lastname: Wang
authors.forename: Q
authors.initials: Q
authors.lastname: Ma
authors.forename: A S
authors.initials: AS
authors.lastname: Ding
authors.forename: B X
authors.initials: BX
authors.lastname: Zeng
authors.forename: F Z
authors.initials: FZ
authors.lastname: Wang
mesh_terms: D000818:Animals; D018891:Dentate Gyrus / Q000503:physiopathology*; D005071:Evoked Potentials; D000860:Hypoxia / Q000503:physiopathology*; D017774:Long-Term Potentiation; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley