title: Biological mesh in hernia repair, abdominal wall defects, and reconstruction and treatment of pelvic organ prolapse: a review of the clinical evidence.
abstract: The use of biological meshes seems to be an innovation that influences all surgical fields. The existing evidence indicates that biological meshes cannot only be applied on the area of hernia repair, but also on cases of abdominal reconstruction and pelvic organ prolapse treatment, especially in the presence of contaminated or potentially contaminated surgical fields. Low risks of graft rejection, complications, and infection seem to be the main advantages of biological meshes in comparison with the synthetic nonabsorbable ones. Nevertheless, the elevated costs suggest that biological mesh implantation should be evaluated in correlation to the needs of each clinical case.
authors.affiliation: Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece. g.peppas@aibs.gr
authors.forename: George
authors.initials: G
authors.lastname: Peppas
authors.forename: Ioannis D
authors.initials: ID
authors.lastname: Gkegkes
authors.forename: Marinos C
authors.initials: MC
authors.lastname: Makris
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Falagas
mesh_terms: D034861:Abdominal Wall / Q000473:pathology / Q000601:surgery*; D001672:Biocompatible Materials; D046449:Hernia, Abdominal / Q000601:surgery*; D006801:Humans; D056887:Pelvic Organ Prolapse / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D013526:Surgical Mesh; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials