title: MRI of the left atrium: predicting clinical outcomes in patients with atrial fibrillation.
abstract: Atrial fibrillation is a significant public health burden, with clinically, epidemiologically and economically significant repercussions. In the last decade, catheter ablation has provided an improvement in morbidity and quality of life, significantly reducing long-term healthcare costs and avoiding recurrences compared with drug therapy. Despite recent progress in techniques, current catheter ablation success rates fall short of expectations. Late gadolinium-enhancement cardiovascular MRI is a well-established tool to image the myocardium and, most specifically, the left atrium. Unique imaging protocols allow for left atrial structural remodeling and fibrosis assessment, which has been demonstrated to correlate with clinical outcomes after catheter ablation, assessment of the individual's risks of thromboembolic events, and effective imaging of patients with left atrial appendage thrombus. Late gadolinium-enhancement MRI aids in the individualized treatment of atrial fibrillation, stratifying recurrence risk and guiding specific ablation strategies. Real-time MRI offers significant safety and effectiveness profiles that would optimize the invasive treatment of atrial fibrillation.
authors.affiliation: Division of Cardiology, University of Utah Health Sciences Center, 30 North 1900 East, Room 4A100, Salt Lake City, UT 84132, USA.
authors.forename: Marcos
authors.initials: M
authors.lastname: Daccarett
authors.forename: Chris J
authors.initials: CJ
authors.lastname: McGann
authors.forename: Nazem W
authors.initials: NW
authors.lastname: Akoum
authors.forename: Rob S
authors.initials: RS
authors.lastname: MacLeod
authors.forename: Nassir F
authors.initials: NF
authors.lastname: Marrouche
mesh_terms: D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy*; D003935:Diagnostic Techniques, Cardiovascular / Q000639:trends*; D005355:Fibrosis / Q000175:diagnosis; D006325:Heart Atria / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000639:trends; D016896:Treatment Outcome; D020257:Ventricular Remodeling