title: Maternal serum and cord blood preptin levels in gestational diabetes mellitus.
abstract: OBJECTIVE
  To assess preptin concentrations in pregnant women with and without gestational diabetes mellitus (GDM) and in the cord blood of their fetuses.
  
  
  METHODS
  In all, 31 pregnant women with GDM and 31 gestational age-matched healthy pregnant subjects participated. Maternal serum and cord blood preptin levels were measured with ELISA. The relationships between maternal serum and cord blood preptin levels, anthropometric and metabolic parameters were also assessed.
  
  
  RESULTS
  Maternal serum and cord blood preptin levels were found higher in patients with GDM compared with control pregnant women. Preptin concentration in maternal serum was positively correlated with maternal age, fasting insulin levels, 1-h blood glucose after glucose load and cord preptin concentrations at birth. However, relationships between maternal and/or cord serum preptin and fetal growth parameters at birth were not detected.
  
  
  CONCLUSIONS
  Our results indicate that preptin concentrations increase in maternal serum of women with GDM. Preptin levels may provide a novel approach to identify women with GDM.
authors.affiliation: Department of Pediatrics, Inonu University School of Medicine, Malatya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Aslan
authors.forename: O
authors.initials: O
authors.lastname: Celik
authors.forename: N
authors.initials: N
authors.lastname: Karsavuran
authors.forename: N
authors.initials: N
authors.lastname: Celik
authors.forename: D G
authors.initials: DG
authors.lastname: Dogan
authors.forename: E
authors.initials: E
authors.lastname: Botan
authors.forename: A
authors.initials: A
authors.lastname: Kafkasli
mesh_terms: D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis; D005260:Female; D005312:Fetal Blood; D005333:Fetus / Q000378:metabolism; D005865:Gestational Age; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D007335:Insulin-Like Growth Factor II; D008423:Maternal Age; D010446:Peptide Fragments / Q000097:blood*; D011247:Pregnancy; D012307:Risk Factors
chemical_list: D001786:Blood Glucose; D007328:Insulin; D010446:Peptide Fragments; C443100:preptin; D007335:Insulin-Like Growth Factor II