title: Effects of a structured exercise program on insulin resistance, inflammatory markers and physical fitness in obese Korean children.
abstract: Thirty-eight obese Korean children (21 boys, 17 girls), whose ages were between 9 and 15, were divided into either the intervention group (19 obese children: BMI>95P) or the age- and sex-matched obese control group. The intervention group performed an intensive exercise program under the supervision of educated instructors for 12 weeks (90 minutes/day, two days/week) and received lifestyle modification counseling using food diaries and phone calls. The control group participated in conventional counseling at an out-patient clinic. The intervention group appeared to have more improvement of body weight, body composition, serum lipid profiles and high-sensitivity C-reactive protein (hs-CRP) levels (P < 0.05) but without changes in serum adiponectin level. HOMA-IR decreased from 2.3 to 1.3 in the intervention group. Maximal oxygen consumption (VO2 max) and other physical fitness parameters were significantly improved after the intervention program (P < 0.05).
authors.affiliation: Department of Pediatrics, Yonsei University, Seoul, Korea.
authors.forename: Hyun-Wook
authors.initials: HW
authors.lastname: Chae
authors.forename: Yu-Na
authors.initials: YN
authors.lastname: Kwon
authors.forename: Young-Jun
authors.initials: YJ
authors.lastname: Rhie
authors.forename: Ho-Seong
authors.initials: HS
authors.lastname: Kim
authors.forename: Yu-Sik
authors.initials: YS
authors.lastname: Kim
authors.forename: Il-Young
authors.initials: IY
authors.lastname: Paik
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Suh
authors.forename: Duk-Hee
authors.initials: DH
authors.lastname: Kim
mesh_terms: D052242:Adiponectin / Q000097:blood; D000293:Adolescent; D044466:Asian People; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000209:etiology; D002648:Child; D015444:Exercise; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000378:metabolism*; D010101:Oxygen Consumption; D010809:Physical Fitness
chemical_list: D052242:Adiponectin; D008055:Lipids; D002097:C-Reactive Protein