title: Sulfur mustard-induced poikiloderma: a case report.
abstract: Sulfur mustard (SM) is a potent chemical warfare agent that was widely used during the First World War and the Iran-Iraq conflict. This vesicant agent causes several acute and chronic effects on the skin, eye, and respiratory system. We report the case of a 41-year-old man who was injured with SM in Iraq chemical attack in 1988. After exposure, he developed severe skin blisters on his upper trunk, dorsum of hands, and genitalia. Based on several clinical observations, such as atrophy, pigmentation, and vascular changes on genitalia with relevant findings in histopathological studies, persistent pigmentation, and damaged skin appendix in hand lesions, a diagnosis of "SM-induced poikiloderma" was postulated. The absence of any complication on the palmar aspect of hands is another remarkable finding in presented case, which suggests a plausible role of the palms as a vector for transporting SM to other sites of the skin.
authors.affiliation: Mazandaran University of Medical Sciences (MUMS), Sari, Iran. seyednaser_emadi@yahoo.com
authors.forename: Seyed Naser
authors.initials: SN
authors.lastname: Emadi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kaffashi
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Poursaleh
authors.forename: Jamal
authors.initials: J
authors.lastname: Akhavan-Moghaddam
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Soroush
authors.forename: Seyed Emad
authors.initials: SE
authors.lastname: Emadi
authors.forename: Nez'hat-o-Sadat
authors.initials: NO
authors.lastname: Taghavi
mesh_terms: D000328:Adult; D002619:Chemical Warfare Agents / Q000633:toxicity*; D017453:Dermatitis, Irritant / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D008297:Male; D009151:Mustard Gas / Q000633:toxicity*
chemical_list: D002619:Chemical Warfare Agents; D009151:Mustard Gas