title: Prostate cancer: New answers prompt new questions regarding cell of origin.
abstract: Controversies remain regarding the precise cell type from which prostate cancers originate. in the last 2 years, two separate studies have arrived at apparently conflicting models for the cell type involved in prostate cancer initiation. However, these results are not mutually exclusive: there are potential solutions, and alternative views on the initiating cell derivation of prostate tumors also exist.
authors.affiliation: The Brady Urological Research Institute and The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. ademarz@jhmi.edu
authors.forename: Angelo M
authors.initials: AM
authors.lastname: De Marzo
authors.forename: William G
authors.initials: WG
authors.lastname: Nelson
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Bieberich
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Yegnasubramanian
mesh_terms: D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*