title: A novel single-labeled fluorescent oligonucleotide probe for mercury(II) ion detection: using the inherent quenching of deoxyguanosines.
abstract: A novel single-labeled fluorescent oligonucleotide (OND) probe for the detection of nanomolar mercury(II) ion in aqueous solution is developed based on the inherent quenching of deoxyguanosines. The formation of hairpin structure of OND-Hg(2+) complex brings deoxyguanosines close to dye, resulting in decreased dye fluorescence due to photoinduced electron transfer from dye to deoxyguanosines.
authors.affiliation: State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Jingqi
authors.initials: J
authors.lastname: Tian
authors.forename: Hailong
authors.initials: H
authors.lastname: Li
authors.forename: Yingwei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xuping
authors.initials: X
authors.lastname: Sun
mesh_terms: D003849:Deoxyguanosine / Q000737:chemistry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D008628:Mercury / Q000032:analysis*; D009690:Nucleic Acid Conformation; D015345:Oligonucleotide Probes / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D015345:Oligonucleotide Probes; D008628:Mercury; D003849:Deoxyguanosine