title: Disseminated superficial porokeratosis.
abstract: A 62-year-old woman with psoriasis and psoriatic arthritis presented for evaluation and treatment of a one-week history of pruritic, pink spots on her trunk and extremities. Several weeks prior, therapy with certolizumab pegol and methotrexate was started for her psoriatic arthritis. A biopsy specimen was consistent with the diagnosis of porokeratosis. Owing to the setting of immunosuppression and presence of symmetric pruritic lesions on non-sun exposed areas, the diagnosis of disseminated superficial porokeratosis was made.
authors.affiliation: Department of Dermatology, New York University, New York, NY, USA.
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Brauer
authors.forename: Rajni
authors.initials: R
authors.lastname: Mandal
authors.forename: Ruth
authors.initials: R
authors.lastname: Walters
authors.forename: Gary
authors.initials: G
authors.lastname: Solomon
authors.forename: Roopal V
authors.initials: RV
authors.lastname: Kundu
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Strober
mesh_terms: D061067:Antibodies, Monoclonal, Humanized; D015535:Arthritis, Psoriatic / Q000188:drug therapy; D001706:Biopsy; D002097:C-Reactive Protein / Q000378:metabolism; D000068582:Certolizumab Pegol; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000009:adverse effects* / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009504:Neutrophils; D011092:Polyethylene Glycols / Q000009:adverse effects* / Q000627:therapeutic use; D017499:Porokeratosis / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D007140:Immunoglobulin Fab Fragments; D007166:Immunosuppressive Agents; D011092:Polyethylene Glycols; D002097:C-Reactive Protein; D000068582:Certolizumab Pegol; D008727:Methotrexate