title: Hypertrophic discoid lupus erythematosus.
abstract: Hypertrophic discoid lupus erythematosus is a distinct form of chronic cutaneous (discoid) lupus, which is characterized by hyperkeratotic plaques that typically are observed over the face, arms, and upper trunk. We present the case of a 43-year-old man with verrucous plaques that were distributed symmetrically over the face, who initially was treated with oral antibiotics and topical glucocorticoids for acne vulgaris. A biopsy specimen confirmed the diagnosis of hypertrophic discoid lupus erythematosus. The clinical and histopathologic features of this clinical variant are reviewed.
authors.affiliation: Department of Dermatology, New York University, New York, NY, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Farley-Loftus
authors.forename: Sarina B
authors.initials: SB
authors.lastname: Elmariah
authors.forename: Jonathan
authors.initials: J
authors.lastname: Ralston
authors.forename: Hideko
authors.initials: H
authors.lastname: Kamino
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Franks
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001569:Benzodiazepines / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D000077152:Olanzapine; D012557:Schizoid Personality Disorder / Q000188:drug therapy; D020280:Sertraline / Q000627:therapeutic use; D012907:Smoking; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D014150:Antipsychotic Agents; D005938:Glucocorticoids; D001569:Benzodiazepines; D000077152:Olanzapine; D020280:Sertraline