title: Sugar-sweetened beverages and hypertension.
abstract: Consumption of sugar-sweetened beverages has been associated with the development and maintenance of obesity, as well as the risk for multiple obesity-related comorbidities. Some experts have hypothesized that the effect is entirely associated with excess caloric intake, while others suggest that a component of sweeteners may have a physiologic impact on the development of hypertension, insulin resistance and nonalcoholic fatty liver disease. Chen et al. have presented the first, large-scale clinical trial, assessing the direct effect of modest changes in sweetened drink consumption on blood pressure in a racially diverse population. The study team utilized data from the PREMIER: Lifestyle Interventions for Blood Pressure Control trial, in which 810 adult subjects were randomized to three groups: advice only; comprehensive lifestyle modification aimed at weight loss, increased exercise and dietary sodium reduction; or comprehensive lifestyle modification with incorporation of the Dietary Approach to Stop Hypertension (DASH) diet. Sweetened drink intake was estimated from 24-h subject recall, assessed by unscheduled phone calls to subjects at baseline, 6 months and 18 months. Over the duration of the study, a reduction of one 12-oz serving of sugar-sweetened beverages per day was associated with an average of 1.8 mmHg reduction in systolic blood pressure and an average of 1.1 mmHg reduction in diastolic blood pressure.
authors.affiliation: Baylor College of Medicine, 1102 Bates Street, Ste 260, Houston, TX 77030, USA. dfeig@bcm.edu
authors.forename: Daniel I
authors.initials: DI
authors.lastname: Feig
mesh_terms: D001628:Beverages; D001794:Blood Pressure; D019422:Dietary Sucrose / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000209:etiology* / Q000517:prevention & control; D008019:Life Style; D011939:Mental Recall; D015999:Multivariate Analysis; D016032:Randomized Controlled Trials as Topic; D012044:Regression Analysis; D018709:Statistics, Nonparametric; D014481:United States
chemical_list: D019422:Dietary Sucrose