title: Management of a locally invasive central giant cell granuloma (CGCG) of mandible: report of an extraordinary large case.
abstract: Central Giant Cell Granuloma (CGCG) is a benign tumour of the jaws. The site most frequently involved is the anterior part of mandible, especially in females under 30 years of age. The traditional treatment of CGCG is curettage. Resection is indicated in locally aggressive cases. This report presents the management of a massive CGCG in a 13-year-old girl with its non-surgical and surgical treatments. The non-surgical treatment with corticosteroid therapy was difficult and unsuccessful. Surgical treatment was performed successfully and at 2-year follow-up showed no recurrence of the lesion.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Shirani
authors.forename: Amir J
authors.initials: AJ
authors.lastname: Abbasi
authors.forename: Simin Z
authors.initials: SZ
authors.lastname: Mohebbi
authors.forename: Iman
authors.initials: I
authors.lastname: Shirinbak
mesh_terms: D000293:Adolescent; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006101:Granuloma, Giant Cell / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D015552:Injections, Intralesional; D008336:Mandibular Diseases / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide