title: Impact of the content of collagens I and III and their ratio in cancer patients for the formation of postoperative ventral hernia.
abstract: Comparative morphological analysis of collagens I and III content in the connective tissue in various groups of surgical patients, including tumor patients with ventral hernias, was carried out. The total content of collagen and collagen I/III ratio were the highest in cancer patients in comparison with non-tumor patients with hernias and with patients without hernias or tumors. Hence, factors not associated with collagen synthesis predominate in the pathogenesis of hernia formation in patients operated for malignant tumors.
authors.affiliation: Penza Institute for Continuous Medical Education, the Russian Ministry of Health, Regional Oncological Center, Penza, Russia. oncology@sura.ru
authors.forename: Ju I
authors.initials: JI
authors.lastname: Zimin
authors.forename: D A
authors.initials: DA
authors.lastname: Chichevatov
authors.forename: E E
authors.initials: EE
authors.lastname: Ponomareva
mesh_terms: D000005:Abdomen / Q000601:surgery; D024042:Collagen Type I / Q000378:metabolism*; D024061:Collagen Type III / Q000378:metabolism*; D003238:Connective Tissue / Q000737:chemistry*; D005260:Female; D006555:Hernia, Ventral / Q000209:etiology*; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000378:metabolism*
chemical_list: D024042:Collagen Type I; D024061:Collagen Type III