title: Interspecies dissemination of the bla gene encoding PER-1 extended-spectrum β-lactamase.
abstract: PER-1 extended-spectrum β-lactamase-producing Gram-negative bacilli are resistant to oxyimino-cephalosporins. However, the bla(PER-1) gene has never been reported in Klebsiella pneumoniae. Here, we studied interspecies dissemination of the bla(PER-1) gene by horizontal transfer of Tn1213 among Acinetobacter baumannii, Pseudomonas aeruginosa, and K. pneumoniae. In a K. pneumoniae clinical isolate, the bla(PER-1) gene was located on a 150-kbp incompatibility group A/C plasmid.
authors.affiliation: Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Il Kwon
authors.initials: IK
authors.lastname: Bae
authors.forename: Sook Jin
authors.initials: SJ
authors.lastname: Jang
authors.forename: Juwon
authors.initials: J
authors.lastname: Kim
authors.forename: Seok Hoon
authors.initials: SH
authors.lastname: Jeong
authors.forename: Byungkyu
authors.initials: B
authors.lastname: Cho
authors.forename: Kyungwon
authors.initials: K
authors.lastname: Lee
mesh_terms: D040981:Acinetobacter baumannii / Q000201:enzymology / Q000235:genetics; D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases