title: [Should children be treated with ephedrine mixture?].
abstract: Lower respiratory tract infections are common in small children, and are often associated with obstruction of the respiratory tract and coughing. In Norway, symptomatic treatment with ephedrine is common in children. The clinical effect of such treatment is not sufficiently documented and serious adverse drug reactions have been reported in small children administered sympathomimetic medication. This article presents current knowledge of clinical effects and adverse drug reactions of ephedrine in infants and children, and discusses the practical implications of these findings.
authors.affiliation: Kompetansesenteret for klinisk forskning, Klinisk forskningspost – barn, Haukeland universitetssykehus, 5021 Bergen, Norway.
authors.forename: Ansgar
authors.initials: A
authors.lastname: Berg
authors.forename: Kari
authors.initials: K
authors.lastname: Furu
authors.forename: Margrete
authors.initials: M
authors.lastname: Einen
authors.forename: Olav
authors.initials: O
authors.lastname: Spigset
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000996:Antitussive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003371:Cough / Q000188:drug therapy; D004809:Ephedrine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D012141:Respiratory Tract Infections / Q000188:drug therapy; D013566:Sympathomimetics / Q000008:administration & dosage*
chemical_list: D000996:Antitussive Agents; D013566:Sympathomimetics; D004809:Ephedrine