title: Addressable electrode array device with IDA electrodes for high-throughput detection.
abstract: An electrochemical device is proposed for high-throughput electrochemical detection that consists of 32 row and 32 column electrodes on a single glass substrate. The row and column electrodes are connected to interdigitated array (IDA) electrodes to form 1024 (32 × 32) addressable sensor points in the device. Electrochemical responses from each of the 1024 sensors were successfully acquired on the device within 1 min using redox cycling at individual IDA electrodes, which ensures application of the device to comprehensive, high-throughput electrochemical detection for enzyme-linked immunosorbent assay (ELISA), reporter gene assay for monitoring gene expressions, and DNA analysis.
authors.affiliation: Graduate School of Environmental Studies, Tohoku University, Sendai, Japan. ino.kosuke@bioinfo.che.tohoku.ac.jp
authors.forename: Kosuke
authors.initials: K
authors.lastname: Ino
authors.forename: Wataru
authors.initials: W
authors.lastname: Saito
authors.forename: Masahiro
authors.initials: M
authors.lastname: Koide
authors.forename: Taizo
authors.initials: T
authors.lastname: Umemura
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Shiku
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Matsue
mesh_terms: D015374:Biosensing Techniques; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D020869:Gene Expression Profiling / Q000295:instrumentation; D017930:Genes, Reporter; D057166:High-Throughput Screening Assays / Q000379:methods*; D056656:Lab-On-A-Chip Devices