title: Aminopropyl-functionalized ethane-bridged periodic mesoporous organosilica spheres: preparation and application in liquid chromatography.
abstract: A synthetic approach for synthesizing spherical aminopropyl-functionalized ethane-bridged periodic mesoporous organosilicas (APEPMOs) is reported. The mesoporous material was prepared by a one-step co-condensation of 1,2-bis(triethoxysilyl)ethane (BTSE) and 3-aminopropyltriethoxysilane (APTES) using cetyltrimethylammonium chlorine (C(18)TACl) as a template with the aid of a co-solvent (methanol) in basic medium. The APEPMOs were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), powder X-ray diffraction (XRD), nitrogen sorption measurement, Fourier transform infrared spectroscopy (FT-IR) and elemental analysis. It was shown that this material exhibited spherical morphology, ordered cubic mesostructure and good mechanical strength. The APEPMOs were tested as a potential stationary phase for liquid chromatography (LC) because the column exhibited reduced back pressure. Moreover, they exhibited good chemical stability in basic mobile phase, which can be ascribed to the ethane groups in the mesoporous framework.
authors.affiliation: Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: Di
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Hao
authors.forename: Fang
authors.initials: F
authors.lastname: Yan
authors.forename: Mengxiang
authors.initials: M
authors.lastname: Su
mesh_terms: D001554:Benzene / Q000737:chemistry; D002853:Chromatography, Liquid / Q000379:methods*; D004980:Ethane / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D046529:Microscopy, Electron, Transmission; D008863:Microspheres; D017646:Organosilicon Compounds / Q000737:chemistry*; D010316:Particle Size; D016062:Porosity; D011312:Pressure; D011437:Propylamines; D012821:Silanes / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D017646:Organosilicon Compounds; D011437:Propylamines; D012821:Silanes; C515211:1,2-bis(triethoxysilyl)ethane; D001554:Benzene; C477625:amino-propyl-triethoxysilane; D004980:Ethane