title: Substituent control over dimerization affinity of triply hydrogen bonded heterodimers.
abstract: Linear arrays of hydrogen bonds represent important elements of the supramolecular toolkit for receptor design, assembly of supramolecular polymers, and other well-defined supramolecular structures. It is illustrated that remote substituent effects control dimerization affinity in a predictable manner using a conformer independent ureidoimidazole DDA motif and its amidoisocytosine based AAD partner.
authors.affiliation: School of Chemistry, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK.
authors.forename: Adam
authors.initials: A
authors.lastname: Gooch
authors.forename: Andrea M
authors.initials: AM
authors.lastname: McGhee
authors.forename: Maria L
authors.initials: ML
authors.lastname: Pellizzaro
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Lindsay
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Wilson
mesh_terms: D003596:Cytosine / Q000031:analogs & derivatives / Q000737:chemistry; D019281:Dimerization; D006860:Hydrogen Bonding; D007093:Imidazoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D011728:Pyridones / Q000737:chemistry; D014508:Urea / Q000031:analogs & derivatives* / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D011108:Polymers; D011728:Pyridones; D003596:Cytosine; D014508:Urea