title: Balancing incompatible endoprosthetic design goals: a combined ingrowth and bone remodeling simulation.
abstract: In order to design a good cementless femoral implant many requirements need to be fulfilled. For instance, the range of micromotions at the bone-implant interface should not exceed a certain threshold and a good ratio between implant-bone stiffness that does not cause bone resorption, needs to be ensured. Stiff implants are known to evoke lower interface micromotions but at the same time they may cause extensive resorption of the surrounding bone. Composite stems with reduced stiffness give good remodeling results but implant flexibility is likely to evoke high micromotions proximally. Finding a good balance between these incompatible design goals is very challenging. The current study proposes a finite element methodology that employs subsequent ingrowth and remodeling simulations and can be of assistance when designing new implants. The results of our simulations for the Epoch stem were in a good agreement with the clinical data. The proposed implant design made of porous tantalum with an inner CoCrMo core performed slightly better with respect to the Epoch stem and considerably better with respect to a Ti alloy stem. Our combined ingrowth and remodeling simulation can be a useful tool when designing a new implant that well balances mentioned incompatible design goals.
authors.affiliation: Orthopaedic Research Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. M.Tarala@orthop.umcn.nl
authors.forename: M
authors.initials: M
authors.lastname: Tarala
authors.forename: D
authors.initials: D
authors.lastname: Janssen
authors.forename: N
authors.initials: N
authors.lastname: Verdonschot
mesh_terms: D000369:Aged, 80 and over; D016723:Bone Remodeling; D005269:Femur / Q000254:growth & development* / Q000502:physiology*; D020342:Finite Element Analysis; D006040:Goals; D006801:Humans; D008297:Male; D011474:Prosthesis Design / Q000379:methods*; D013635:Tantalum; D013997:Time Factors
chemical_list: D013635:Tantalum