title: RF hydrazine plasma modification of chitosan for antibacterial activity and nanofiber applications.
abstract: Chitosan nano powders were modified using RF hydrazine plasma produced at low pressure (26.66Pa) with 13.56MHz frequency at a power of 100W for 30min. Characterization and investigation of the properties of plasma-modified chitosan (PMCh) and non-modified chitosan (Ch) were carried out using an optical monochromator, FTIR, florescence analysis, TGA, SEM, and X-ray techniques. FTIR spectra of PMCh indicated a band broadening at 3436cm(-1) that confirmed increasing functional groups based on H-bonding. The number of NH(2) groups was determined from fluorescence analysis. TGA analysis shows that the moisture absorption is three times higher in the PMCh structure. Ch and PMCh in PVA solutions were used to produce nanofibers by the electrospinning method; average fiber diameters were 480 and 280nm for Ch and PMCh, respectively. It was found that the antibacterial effect of PMCh is better than the Ch for Gram-positive strains.
authors.affiliation: Suleyman Demirel University, Faculty of Arts and Science, Department of Chemistry, 32260 Isparta, Turkey. aysegul@fef.sdu.edu.tr
authors.forename: Aysegul
authors.initials: A
authors.lastname: Uygun
authors.forename: Melek
authors.initials: M
authors.lastname: Kiristi
authors.forename: Lutfi
authors.initials: L
authors.lastname: Oksuz
authors.forename: Sorin
authors.initials: S
authors.lastname: Manolache
authors.forename: Seyhan
authors.initials: S
authors.lastname: Ulusoy
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology; D005453:Fluorescence; D006834:Hydrazines / Q000737:chemistry* / Q000494:pharmacology; D057139:Nanofibers / Q000737:chemistry*; D058626:Plasma Gases / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000900:Anti-Bacterial Agents; D006834:Hydrazines; D058626:Plasma Gases; C029424:hydrazine; D048271:Chitosan