title: No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression.
abstract: In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.
authors.affiliation: Institute of Psychiatry, University of Bologna, Bologna, Italy. alessandro.serretti@unibo.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Serretti
authors.forename: Alberto
authors.initials: A
authors.lastname: Chiesa
authors.forename: Raffaella
authors.initials: R
authors.lastname: Calati
authors.forename: Isabelle
authors.initials: I
authors.lastname: Massat
authors.forename: Sylvie
authors.initials: S
authors.lastname: Linotte
authors.forename: Siegfried
authors.initials: S
authors.lastname: Kasper
authors.forename: Yves
authors.initials: Y
authors.lastname: Lecrubier
authors.forename: Martin
authors.initials: M
authors.lastname: Fink
authors.forename: Irina
authors.initials: I
authors.lastname: Antonijevic
authors.forename: Carlos
authors.initials: C
authors.lastname: Forray
authors.forename: Lenore
authors.initials: L
authors.lastname: Snyder
authors.forename: Joseph
authors.initials: J
authors.lastname: Bollen
authors.forename: Joseph
authors.initials: J
authors.lastname: Zohar
authors.forename: Diana
authors.initials: D
authors.lastname: De Ronchi
authors.forename: Daniel
authors.initials: D
authors.lastname: Souery
authors.forename: Julien
authors.initials: J
authors.lastname: Mendlewicz
mesh_terms: D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D051546:Cyclooxygenase 2 / Q000235:genetics*; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010597:Pharmacogenetics; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: D000928:Antidepressive Agents; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human