title: A RNA interference screen identifies RIP3 as an essential inducer of TNF-induced programmed necrosis.
authors.affiliation: Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
authors.forename: Youngsik
authors.initials: Y
authors.lastname: Cho
authors.forename: Sreerupa
authors.initials: S
authors.lastname: Challa
authors.forename: Francis Ka-Ming
authors.initials: FK
authors.lastname: Chan
mesh_terms: D005820:Genetic Testing; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D009336:Necrosis / Q000378:metabolism / Q000473:pathology*; D011485:Protein Binding; D034622:RNA Interference; D017382:Reactive Oxygen Species / Q000378:metabolism; D053422:Receptor-Interacting Protein Serine-Threonine Kinases / Q000378:metabolism*; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000166:cytology / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*; D014780:Viruses / Q000276:immunology
chemical_list: D017382:Reactive Oxygen Species; D014409:Tumor Necrosis Factor-alpha; C119705:RIPK3 protein, human; D053422:Receptor-Interacting Protein Serine-Threonine Kinases