title: [Changes of glycine uptake of synaptosomes of rat spinal cord in 0.7 MPa (7ATA) air pressure].
abstract: OBJECTIVE
  To study changes of function of transmitter glycine in nitrogen narcosis.
  
  
  METHODS
  Synaptosomes of rat spinal cord were prepared. Glycine uptake of synaptosomes of rat spinal cord in 0.7 MPa (7ATA) hyperbaric air pressure was observed by the methods of isotope.
  
  
  RESULTS
  Glycine uptake slowed down and took a longer period of time to reach saturation in 0.7 MPa (7ATA). The maximum glycine uptake was lessened. Vm was diminished, but Km was increased. Vm rose in 0.7 MPa (7ATA) when corticosterone was added.
  
  
  CONCLUSIONS
  When nitrogen narcosis arose in 0.7 MPa (7ATA), the function of transporters of glycine re-uptake was reduced, the affinity of glycine for transporters subsided. Corticosterone was conductive to the recovery of the function of glycine transporters of high affinity.
authors.affiliation: Diving Medical Research Department, Navy Medical Research Institute, Shanghai 200433, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Bi
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.forename: Jing-Chang
authors.initials: JC
authors.lastname: Liu
mesh_terms: D000399:Air Pressure; D000818:Animals; D005998:Glycine / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000378:metabolism*; D013574:Synaptosomes / Q000378:metabolism*
chemical_list: D005998:Glycine