title: Enhancing credibility of chemical safety studies: emerging consensus on key assessment criteria.
abstract: OBJECTIVE
  We examined the extent to which consensus exists on the criteria that should be used for assessing the credibility of a scientific work, regardless of its funding source, and explored how these criteria might be implemented.
  
  
  METHODS
  Three publications, all presented at a session of the 2009 annual meeting of the Society for Risk Analysis, have proposed a range of criteria for evaluating the credibility of scientific studies. At least two other similar sets of criteria have recently been proposed elsewhere.
  
  
  METHODS
  In this article we review these criteria, highlight the commonalities among them, and integrate them into a list of 10 criteria. We also discuss issues inherent in any attempt to implement the criteria systematically.
  
  
  CONCLUSIONS
  Recommendations by many scientists and policy experts converge on a finite list of criteria for assessing the credibility of a scientific study without regard to funding source. These criteria should be formalized through a consensus process or a governmental initiative that includes discussion and pilot application of a system for reproducibly implementing them. Formal establishment of such a system should enable the debate regarding chemical studies to move beyond funding issues and focus on scientific merit.
authors.affiliation: Conrad Law and Policy Counsel, Washington, DC 20036, USA. jamie@conradcounsel.com
authors.forename: James W
authors.initials: JW
authors.lastname: Conrad
authors.forename: Richard A
authors.initials: RA
authors.lastname: Becker
mesh_terms: D000818:Animals; D016265:Conflict of Interest; D032921:Consensus; D004782:Environmental Health / Q000331:legislation & jurisprudence / Q000592:standards*; D004785:Environmental Pollutants / Q000633:toxicity*; D033161:Government Regulation; D006801:Humans; D017712:Peer Review, Research / Q000331:legislation & jurisprudence / Q000592:standards; D018570:Risk Assessment
chemical_list: D004785:Environmental Pollutants