title: Anesthetic management of a child with Aicardi syndrome undergoing laparoscopic Nissen's fundoplication: a case report.
abstract: Aicardi syndrome (AS) is a rare congenital syndrome and is characterized by the triad of infantile spasm, agenesis of the corpus callosum, and anomaly of chorioretinal lacunae. We here report a case of a patient with AS under general anesthesia. Although there is no report in which muscle relaxants were used in AS patients, vecuronium bromide was used for artificial pneumoperitoneum in this case. Careful management is important for AS patients during an operation that significantly affects respiratory function. In addition, it is possible that muscle relaxants be administered safely in AS patients. Careful monitoring such as epileptiform electroencephalogram and bispectral index monitors may be needed for the early detection of epileptic activities.
authors.affiliation: Department of Dental Anesthesiology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan. terakawayui@tdc.ac.jp
authors.forename: Yui
authors.initials: Y
authors.lastname: Terakawa
authors.forename: Takaaki
authors.initials: T
authors.lastname: Miwa
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Mizuno
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ichinohe
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Koui
authors.initials: K
authors.lastname: Ka
mesh_terms: D058540:Aicardi Syndrome / Q000601:surgery*; D000768:Anesthesia, General; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D056805:Consciousness Monitors; D004569:Electroencephalography; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000150:complications / Q000517:prevention & control; D006801:Humans; D007431:Intraoperative Complications / Q000175:diagnosis / Q000188:drug therapy; D010535:Laparoscopy; D003473:Neuromuscular Nondepolarizing Agents; D011028:Pneumoperitoneum, Artificial; D011182:Postoperative Care; D012121:Respiration, Artificial; D012640:Seizures / Q000175:diagnosis / Q000517:prevention & control; D014673:Vecuronium Bromide
chemical_list: D000927:Anticonvulsants; D003473:Neuromuscular Nondepolarizing Agents; D014673:Vecuronium Bromide