title: [Premedication with oral midazolam in children receive sevoflurane general anesthesia].
abstract: OBJECTIVE
  To investigate the effect of oral midazolam on sedation, on perioperative emotion and on behavior in children with sevoflurane general anesthesia.
  
  
  METHODS
  48 children undergoing cataract surgeries were randomly divided into two groups and respectively received 0.5 mg/kg oral midazolam (Group I)and placebo (Group II) 30 minutes before the operation. Perioperative behavior and emotion status were assessed.
  
  
  RESULTS
  Satisfactory sedation ratio in group I was better than that in group II (58.3% vs 12.5%, P < 0.05). There were no differences in emergence time, PACU stay and incidence of emergence agitation between two groups (P > 0.05).
  
  
  CONCLUSIONS
  0.5 mg/kg oral midazolam before sevoflurane general anesthesia in children is safe. It is effective on anxious relief, however it does not decrease the incidence of emergence agitation.
authors.affiliation: Department of Anesthesiology, Capital Medical University, Beijing 100730, China.
authors.forename: Xue-ying
authors.initials: XY
authors.lastname: Jiang
authors.forename: Tian-zuo
authors.initials: TZ
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Li
mesh_terms: D000769:Anesthesia, Inhalation / Q000379:methods*; D002386:Cataract / Q000151:congenital / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008738:Methyl Ethers; D008874:Midazolam / Q000008:administration & dosage / Q000627:therapeutic use*; D011292:Premedication; D000077149:Sevoflurane; D016037:Single-Blind Method
chemical_list: D008738:Methyl Ethers; D000077149:Sevoflurane; D008874:Midazolam