title: New phosphorus-containing spherical carbon adsorbents as promising materials in drug adsorption and release.
abstract: A simple method of preparation of new high surface area spherical carbon adsorbents is presented. The phosphoric acid activation upon hydrothermally formed spherules was employed to produce carbons having controlled high specific surface area (over 2100m(2)/g), large volumes of pores (1.2cm(3)/g), and high acidity. Prepared from sucrose materials show high adsorption capacities (i.e. 220mg/g(C)) toward paracetamol. It is proved that for these materials the contents of surface phosphorus are responsible for the reversibility of drug adsorption/release process.
authors.affiliation: N. Copernicus University, Department of Chemistry, Physicochemistry of Carbon Materials Research Group, Gagarin Street 7, 87-100 Toruń, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Wiśniewski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Pacholczyk
authors.forename: Artur P
authors.initials: AP
authors.lastname: Terzyk
authors.forename: Gerhard
authors.initials: G
authors.lastname: Rychlicki
mesh_terms: D000082:Acetaminophen / Q000302:isolation & purification*; D000327:Adsorption; D018712:Analgesics, Non-Narcotic / Q000302:isolation & purification*; D002244:Carbon / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry*; D010758:Phosphorus / Q000737:chemistry*; D016062:Porosity; D013499:Surface Properties
chemical_list: D018712:Analgesics, Non-Narcotic; D010756:Phosphoric Acids; D010758:Phosphorus; D000082:Acetaminophen; D002244:Carbon; C030242:phosphoric acid