title: Working toward an understanding of the impact of hereditary cancers.
abstract: Hereditary diffuse gastric cancer is a genetically inherited aggressive form of stomach cancer. Once the person is diagnosed as having this gene, they have a 75%-80% chance of inheriting the cancer. People who are at risk of this genetic mutation have to meet many challenges relating to the implications of the disease. An understanding is required by nurses to guide them in the provision of care for those afflicted with this inherited form of gastric cancer. A review of literature has been undertaken relating to other genetically inherited cancers including hereditary nonpolyposis colon cancer, familial adenomatous polyposis, and hereditary lobular breast cancer. The findings from the literature assist nurses in understanding the physical and psychological implications of genetically inherited cancer; however, further study is required to gain a complete understanding of the implications of hereditary diffuse gastric cancer.
authors.affiliation: University of the Sunshine Coast, Maroochydore, Queensland, Australia. aframp@usc.edu.au
authors.forename: Ann
authors.initials: A
authors.lastname: Framp
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000235:genetics; D015703:Antigens, CD; D001943:Breast Neoplasms / Q000235:genetics; D015820:Cadherins / Q000235:genetics; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics; D017281:Cost of Illness; D055088:Early Detection of Cancer; D005260:Female; D005743:Gastrectomy; D005773:Gastroscopy; D020022:Genetic Predisposition to Disease / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control; D005820:Genetic Testing; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics; D009386:Neoplastic Syndromes, Hereditary / Q000453:epidemiology / Q000235:genetics* / Q000523:psychology / Q000628:therapy; D024802:Nurse's Role; D035583:Rare Diseases; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000235:genetics* / Q000523:psychology / Q000628:therapy
chemical_list: D015703:Antigens, CD; C513384:CDH1 protein, human; D015820:Cadherins