title: Comparative evaluation of the effects of an alum-containing mouthrinse and a saturated saline rinse on the salivary levels of Streptococcus mutans.
abstract: BACKGROUND
  The literature is replete with studies establishing Streptococcus mutans as a major player in the formation of pit and fissure caries in all dentitions. Salivary bacterial levels in turn are related to the number of colonized surfaces. Therefore, decreasing the salivary levels of S. mutans would have a great benefit in decreasing the incidence of dental diseases.
  
  
  OBJECTIVE
  Keeping in mind the potential antimicrobial effects of saturated saline and alum solutions, the present study was attempted to compare and evaluate the effects of saturated saline rinse and 0.02 M alum mouthrinse on salivary S. mutans levels in children.
  
  
  METHODS
  The investigation was a double-blind, stratified comparison of three parallel groups of children who used either saturated saline rinse, 0.02 M alum mouthrinse or distilled water (placebo) rinse twice daily under professional supervision for a 21-day period. A total of three saliva samples were taken from each individual - at baseline, on the 10 th day and on the 21 st day, and colony counts of S. mutans were determined. All data were subjected to statistical analysis using Wilcoxon's Signed Ranks Sum and Mann-Whitney "U" test.
  
  
  CONCLUSIONS
  Children using saturated saline rinse and alum rinse showed statistically significant reductions in salivary S. mutans counts after 10 days and also after 21 days. After 21 days, the saturated saline rinse and alum rinse groups showed statistically significant differences over the placebo rinse group. Again, the alum rinse group showed a statistically significant difference over the saturated saline rinse group.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Pushpagiri College of Dental Sciences, Perumthuruthy, Kerala, India. yourpediatricdentist@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Rupesh
authors.forename: J J
authors.initials: JJ
authors.lastname: Winnier
authors.forename: U A
authors.initials: UA
authors.lastname: Nayak
authors.forename: A P
authors.initials: AP
authors.lastname: Rao
authors.forename: N V
authors.initials: NV
authors.lastname: Reddy
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D000534:Alum Compounds / Q000494:pharmacology / Q000627:therapeutic use; D000704:Analysis of Variance; D002648:Child; D004245:DMF Index; D003750:Dental Fissures / Q000517:prevention & control; D004311:Double-Blind Method; D006801:Humans; D009067:Mouthwashes / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D012463:Saliva / Q000382:microbiology*; D012965:Sodium Chloride / Q000494:pharmacology / Q000627:therapeutic use; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D000276:Adjuvants, Immunologic; D000534:Alum Compounds; D009067:Mouthwashes; C041524:aluminum sulfate; D012965:Sodium Chloride