title: Abdominal aortic aneurysm associated with systemic fungal infection in a German shepherd dog.
abstract: A 2 yr old spayed female German shepherd presented with a chief complaint of acute onset paraparesis and weight loss. At presentation, the dog was pyrexic, nonambulatory, and had generalized muscle wasting. Neurolocalization was consistent with a thoracolumbar spinal cord lesion. An abdominal ultrasound was performed and revealed a focal dilation (4 cm) of the terminal aorta with evidence of blood stasis consistent with an aortic aneurysm. The dog was euthanized shortly after admission to the hospital and a post mortem examination was performed. Fungal organisms were identified in the aortic aneurysm as well as from the thoracic vertebrae, mesenteric lymph nodes, axillary lymph nodes, spleen, kidneys, liver, lungs, and heart. Although the morphology was consistent with Candida spp., immunohistochemistry and PCR could not definitively identify the causative organism. Mycotic aortic aneurysms are a rare finding in humans and have not been previously reported in the dog. To the authors' knowledge, this is the first known report of an aortic aneurysm associated with systemic fungal infection in a dog.
authors.affiliation: Angell Animal Medical Center Department of Emergency and Critical Care, Boston, MA, USA. rgershenson@mspca.org
authors.forename: Ryan T
authors.initials: RT
authors.lastname: Gershenson
authors.forename: Raffaele
authors.initials: R
authors.lastname: Melidone
authors.forename: James
authors.initials: J
authors.lastname: Sutherland-Smith
authors.forename: Catherine L
authors.initials: CL
authors.lastname: Rogers
mesh_terms: D000818:Animals; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D002177:Candidiasis / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary