title: Neuronal transport: myosins pull the ER.
abstract: Whether class Vmyosins can work as point-to-point transporters in animal cells is highly debated. Myosin Va is now shown to function as a point-to-point transporter that pulls the endoplasmic reticulum (ER) into dendritic spines, with important consequences for dendritic development and cerebellar motor learning
authors.forename: Michael
authors.initials: M
authors.lastname: Stiess
authors.forename: Frank
authors.initials: F
authors.lastname: Bradke
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000378:metabolism; D049229:Dendritic Spines / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D005260:Female; D007700:Kinetics; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008870:Microtubules / Q000378:metabolism; D008959:Models, Neurological; D018995:Myosin Heavy Chains / Q000235:genetics / Q000378:metabolism*; D024701:Myosin Type V / Q000235:genetics / Q000378:metabolism*; D011689:Purkinje Cells / Q000378:metabolism*; D018091:Receptors, AMPA / Q000378:metabolism
chemical_list: C513082:Myo5a protein, mouse; D018091:Receptors, AMPA; D024701:Myosin Type V; D018995:Myosin Heavy Chains; D002118:Calcium