title: Relationship of adiposity and body composition to the status of metabolic syndrome among ethnic Chinese Taiwanese.
abstract: OBJECTIVE
  The predictive power of adiposity and body compositions measured from bioelectrical impedance analysis (BIA) for identifying the risk of metabolic syndrome is unknown among ethnic Chinese.
  
  
  RESULTS
  We designed a nested case-control study by recruiting 1000 cases of metabolic syndrome and 986 matched controls from a health checkup center. For identifying the metabolic syndrome status, the highest areas under receiver operating characteristic curve (AUCs) were waist-height ratio (WHtR) (0.967, 95% confidence interval [CI], 0.960-0.976). The body fat mass vs. lean body mass and body mass index (BMI) had a similar AUC (0.896 for fat mass vs. lean body mass, 0886 for BMI, P=0.07). WHtR and waist circumference had the highest correctly classified proportions (0.89-0.90) and the highest Youden's index (0.77-0.81). The optimal cut point for WHtR was 52.5, with a sensitivity of 0.92 and specificity of 0.89 for discriminating metabolic syndrome risk. The incremental values of AUC, net reclassification improvement and integrated discrimination improvement values were still highest among WHtR, waist circumference and the percent body fat in the multivariate logistic model.
  
  
  CONCLUSIONS
  Waist circumference and BIA-derived body component measures are suitable for clinical application in identifying the metabolic syndrome status among ethnic Chinese in Taiwan.
authors.affiliation: Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taiwan.
authors.forename: K-L
authors.initials: KL
authors.lastname: Chien
authors.forename: H-J
authors.initials: HJ
authors.lastname: Lin
authors.forename: B-C
authors.initials: BC
authors.lastname: Lee
authors.forename: H-C
authors.initials: HC
authors.lastname: Hsu
authors.forename: M-F
authors.initials: MF
authors.lastname: Chen
mesh_terms: D000273:Adipose Tissue; D050154:Adiposity; D000328:Adult; D000368:Aged; D001827:Body Height; D015992:Body Mass Index; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D017097:Electric Impedance; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology*; D008875:Middle Aged; D015999:Multivariate Analysis; D012372:ROC Curve; D013624:Taiwan / Q000208:ethnology; D055105:Waist Circumference