title: Investigational devices for mitral regurgitation: state of the art.
abstract: The incidence of mitral regurgitation (MR) is rising as a result of an aging population worldwide. Surgical repair or replacement of the mitral valve remains the standard of care for patients with severe MR as the only approach to achieve sustained relief of symptoms or heart failure. However, the majority of patients with severe MR do not undergo surgery because of high perceived perioperative risk. Recently, there has been great enthusiasm in the pursuit of a less invasive percutaneous approach to the treatment of MR to avoid thoracotomy or cardiopulmonary bypass, even if less efficacious. This article reviews the latest developments of various percutaneous options in the treatment of MR.
authors.affiliation: Division of Cardiology, SH Ho Cardiovascular and Stroke Centre, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Yat-Yin
authors.initials: YY
authors.lastname: Lam
authors.forename: Pui-Wai
authors.initials: PW
authors.lastname: Lee
authors.forename: Gerald
authors.initials: G
authors.lastname: Yong
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Yan
mesh_terms: D013504:Cardiovascular Surgical Procedures / Q000295:instrumentation*; D002404:Catheterization / Q000295:instrumentation; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000601:surgery*