title: [C-fos expression within PVN and NTS of the rat induced by gastric ischemia/reperfusion injury].
abstract: OBJECTIVE
  To investigate the effect of paraventricular nucleus (PVN) stimulation and the c-fos expression within PVN and nucleus tractus solitarius (NTS) of the rat following gastric ischemia/reperfusion injury (GI/RI).
  
  
  METHODS
  The rat celiac artery was clamped for thirty minutes and reperfused for sixty minutes, using Fos immunohistochemical method (ABC method) examined the c-fos expression within PVN and NTS.
  
  
  RESULTS
  (1) Both electrical and chemical stimulation of the PVN obviously attenuated the GI/ RI. (2) Bilateral electrolytic lesion of NTS could eliminate the protective effect of electrical stimulation of the PVN. (3) The Fos-like immunoreactive neurons were increased in bilateral PVN and NTS by GI/RI.
  
  
  CONCLUSIONS
  The function of PVN and NTS could be affected by the GI/RI noxious stimulation. PVN, NTS were involved in the regulation of GI/RI.
authors.affiliation: Department of Physiology, Xuzhou Medical College, Xuzhou 221002, China.
authors.forename: Yong-Mei
authors.initials: YM
authors.lastname: Zhang
authors.forename: Jian-Fu
authors.initials: JF
authors.lastname: Zhang
authors.forename: You-Ting
authors.initials: YT
authors.lastname: Chen
authors.forename: Chang-Dong
authors.initials: CD
authors.lastname: Yan
authors.forename: Xiu-Ping
authors.initials: XP
authors.lastname: Zhou
mesh_terms: D000818:Animals; D005753:Gastric Mucosa / Q000473:pathology; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D015427:Reperfusion Injury / Q000378:metabolism*; D017552:Solitary Nucleus / Q000378:metabolism*; D013270:Stomach / Q000098:blood supply
chemical_list: D016760:Proto-Oncogene Proteins c-fos