title: Expression of transforming growth factor-β2in vitreous body and adjacent tissues during prenatal development of human eye.
abstract: Expression of transforming growth factor-β2 was detected by PCR in the vitreous body, lens, retina, and ciliary-iris complex of human eye at early stages of fetal development. Immunochemical assay of the corresponding protein in eye tissues revealed a correlation between the localization of transforming growth factor-β2 and the development of intraocular hyaloid vascular network, its regression, formation of the vitreous body, and development of definite retinal vessels.
authors.affiliation: N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.
authors.forename: G T
authors.initials: GT
authors.lastname: Sukhikh
authors.forename: I G
authors.initials: IG
authors.lastname: Panova
authors.forename: Yu A
authors.initials: YA
authors.lastname: Smirnova
authors.forename: L A
authors.initials: LA
authors.lastname: Milyushina
authors.forename: N V
authors.initials: NV
authors.lastname: Firsova
authors.forename: Yu V
authors.initials: YV
authors.lastname: Markitantova
authors.forename: R A
authors.initials: RA
authors.lastname: Poltavtseva
authors.forename: R D
authors.initials: RD
authors.lastname: Zinov'eva
mesh_terms: D005123:Eye / Q000196:embryology / Q000378:metabolism*; D006801:Humans; D007120:Immunochemistry; D066298:In Vitro Techniques; D016133:Polymerase Chain Reaction; D012160:Retina / Q000378:metabolism; D053781:Transforming Growth Factor beta2 / Q000235:genetics / Q000378:metabolism*; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D053781:Transforming Growth Factor beta2