title: Effects of low-dose γ-irradiation on the counts of immunocompetent cells in a model experiment on primates.
abstract: Cellular immunity was studied by flow cytometry with Becton Dickinson monoclonal antibodies in clinically healthy Macaca mulatta males before and after low-dose exposure to ionizing radiation. It was shown that T and B cells are radiosensitive, B cells being more sensitive, which is seen from a significant drop of their count. Natural killers are radioresistant. The count of immunocompetent cells recovers sooner after single compared to fractionated irradiation in the same summary dose.
authors.affiliation: Institute of Medical Primatology, Russian Academy of Medical Sciences, SochiAdler, Russia. ignatova_i_e@mail.ru
authors.forename: I E
authors.initials: IE
authors.lastname: Ignatova
authors.forename: V Z
authors.initials: VZ
authors.lastname: Agrba
authors.forename: B A
authors.initials: BA
authors.lastname: Lapin
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005434:Flow Cytometry; D005720:Gamma Rays / Q000009:adverse effects*; D007694:Killer Cells, Natural / Q000528:radiation effects*; D008253:Macaca mulatta / Q000276:immunology*; D008297:Male; D011323:Primates; D013601:T-Lymphocytes / Q000528:radiation effects*