title: [Effects of long-term physical training on age-related changes of energy transformation of mice heart mitochondria].
abstract: OBJECTIVE
  To observe effects of long-term physical training (running wheel) on the age-related changes of energy transformation of mice heart mitochondria.
  
  
  RESULTS
  RCR and ADP/O decreased with age in the presence of a-ketoglutaric acid, especially in the late of age, which indicated that oxidative phosphorylation coupling decreased in the aging process.
  
  
  CONCLUSIONS
  Adaptive changes of mitochondria were brought by long-term physical training which might delay the age-related decline of mitochondrial function.
authors.affiliation: Guangzhou Institute of Physical Education, Guangzhou 510075.
authors.forename: J
authors.initials: J
authors.lastname: Lu
authors.forename: C Z
authors.initials: CZ
authors.lastname: Chen
authors.forename: Y G
authors.initials: YG
authors.lastname: Xu
authors.forename: R X
authors.initials: RX
authors.lastname: Lai
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D007656:Ketoglutaric Acids / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008929:Mitochondria, Heart / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010805:Physical Conditioning, Animal / Q000502:physiology*; D012420:Running
chemical_list: D007656:Ketoglutaric Acids