title: Histone demethylation and timely DNA replication.
abstract: It is well-established that silent regions of the genome replicate late during S phase. In this issue of Molecular Cell, Black et al. (2010) uncover a conserved role for the JMJD2 family of histone demethylases in promoting replication within silent chromatin regions that contain histone H3 lysine 9 methylation and HP1.
authors.affiliation: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Erica L
authors.initials: EL
authors.lastname: Gerace
authors.forename: Danesh
authors.initials: D
authors.lastname: Moazed