title: Alimentary tract presentations of brucellosis.
abstract: A retrospective study was conducted to assess alimentary tract involvement in 140 Saudi patients with acute or chronic brucellosis. A brucella standard agglutination titer of 160 or over was considered to be positive evidence of brucella infection. The commonest symptoms were anorexia, weight loss, right hypochondrial pain, and constipation. A history of raw milk ingestion was obtained in 38 patients. Thirty-nine patients had hepatomegaly, 21 had splenomegaly, and six had signs of cholecystitis. Bilirubin was elevated in eight patients; one or more of the liver enzyme activities studied were elevated in 75 patients. Four of the 14 liver biopsies performed revealed Brucella microgranulomata. Abdominal ultrasound studies were abnormal in 29 of 46 patients. Thirty patients had a normal upper or lower gastrointestinal tract endoscopy. Blood cultures from 18 patients were incubated for six to eight weeks, with Brucella melitensis isolated from five. Sixty-seven patients (47.86%) received effective treatment for brucellosis with improvement in the symptoms, signs and liver functions. Brucellosis is relatively common in the Kingdom of Saudi Arabia, and efforts should be taken to control and possibly eradicate this disease.
authors.affiliation: Senior Registrar, Gastroenterology Division, Department of Medicine; Consultant Physician, Department of Medicine; Formerly Consultant Microbiologist, Department of Pathology; and Consultant Physician, Head, Gastroenterology Division, Department of Medicine, Riyadh Armed Forces Hospital, Riyadh, Saudi Arabia.
authors.forename: A el S
authors.initials: Ael S
authors.lastname: Mohamed
authors.forename: D
authors.initials: D
authors.lastname: Ven
authors.forename: M M
authors.initials: MM
authors.lastname: Madkour
authors.forename: M A
authors.initials: MA
authors.lastname: Talukder
authors.forename: M A
authors.initials: MA
authors.lastname: Al Karawi