title: A clinician view and experience of proteomic studies in the light of lung cancer in Japanese healthcare.
abstract: In Japan, rising costs have impacted the framework of maintaining an efficient and effective healthcare system. Today, urgent implementation of programs to address this need have led to a rebuilding of the entire approach of medical evaluation and clinical care. Recent developments in clinical proteomics based on mass spectrometry (MS) for identifying, sequencing, and quantifying disease-relevant protein biomarkers is a promising means for optimal drug prescription using biomarker diagnosis. We illustrate in this report our experience with lung cancer cases with various drug therapies evaluated with proteomics studies.
authors.affiliation: Thoracic Surgery, Niizashiki Chuo General Hospital, Saitama, Japan.
authors.forename: Harubumi
authors.initials: H
authors.lastname: Kato
authors.forename: Toshihide
authors.initials: T
authors.lastname: Nishimura
authors.forename: Takashi
authors.initials: T
authors.lastname: Hirano
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nomura
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Tojo
authors.forename: Kiyonaga
authors.initials: K
authors.lastname: Fujii
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawamura
authors.forename: Sayaka
authors.initials: S
authors.lastname: Mikami
authors.forename: Makoto
authors.initials: M
authors.lastname: Kihara
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Bando
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tsuboi
authors.forename: Norihiko
authors.initials: N
authors.lastname: Ikeda
authors.forename: Gyorgy
authors.initials: G
authors.lastname: Marko-Varga
mesh_terms: D000328:Adult; D000368:Aged; D019540:Area Under Curve; D014408:Biomarkers, Tumor / Q000097:blood*; D003695:Delivery of Health Care; D005260:Female; D006801:Humans; D007564:Japan; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D040901:Proteomics; D012372:ROC Curve
chemical_list: D014408:Biomarkers, Tumor