title: Occurrence of left-sided heart valve involvement before right-sided heart valve involvement in carcinoid heart disease.
abstract: Carcinoids are rare neuroendocrine tumours that occur primarily in the gastrointestinal tract. Carcinoid heart disease is characterized by fibrous plaque deposition on the endocardial surface of the cardiac valves and chambers. It affects the right heart valves in 85% of cases and the left heart valves in 15%. We present an unusual case of a patient with metastatic carcinoid heart disease in whom typical carcinoid aortic and mitral valve lesions developed 2 years prior to the development of severe right-sided carcinoid valvular heart disease.
authors.affiliation: Division of Cardiovascular Diseases and Division of Cardiovascular and Thoracic Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA.
authors.forename: Vidyasagargoud
authors.initials: V
authors.lastname: Marupakula
authors.forename: Karyne L
authors.initials: KL
authors.lastname: Vinales
authors.forename: Mohammad Q
authors.initials: MQ
authors.lastname: Najib
authors.forename: Louis A
authors.initials: LA
authors.lastname: Lanza
authors.forename: Howard R
authors.initials: HR
authors.lastname: Lee
authors.forename: Hari P
authors.initials: HP
authors.lastname: Chaliki
mesh_terms: D000368:Aged; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002275:Carcinoid Heart Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D018450:Disease Progression; D015150:Echocardiography, Doppler / Q000379:methods*; D018618:Echocardiography, Doppler, Color / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D018570:Risk Assessment; D016896:Treatment Outcome; D014262:Tricuspid Valve Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery