title: Modified checklist for autism in toddlers: cross-cultural adaptation and validation in Spain.
abstract: Early detection and treatment have been shown to be effective in reducing disability severity caused by Autistic Spectrum Disorders (ASDs). As Spanish pediatricians have no detection tool, the Modified Checklist for Autism in Toddlers (M-CHAT) was first translated into and culturally adapted to Spanish. Validity and reliability studies were carried out in two different geographical areas of Spain, where M-CHAT was administered to two different samples, namely: 2,480 high- and low-risk children; and 2,055 low-risk children. The results obtained were similar to those yielded by the original M-CHAT studies. Differences were found in positive predictive value, due to the low ASD frequency observed in this study. M-CHAT is still being studied in a large population-based screening program in Spain.
authors.affiliation: University of Salamanca, Salamanca, Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Canal-Bedia
authors.forename: Patricia
authors.initials: P
authors.lastname: García-Primo
authors.forename: María Victoria
authors.initials: MV
authors.lastname: Martín-Cilleros
authors.forename: José
authors.initials: J
authors.lastname: Santos-Borbujo
authors.forename: Zoila
authors.initials: Z
authors.lastname: Guisuraga-Fernández
authors.forename: Lorena
authors.initials: L
authors.lastname: Herráez-García
authors.forename: María del Mar
authors.initials: Mdel M
authors.lastname: Herráez-García
authors.forename: Leticia
authors.initials: L
authors.lastname: Boada-Muñoz
authors.forename: Joaquín
authors.initials: J
authors.lastname: Fuentes-Biggi
authors.forename: Manuel
authors.initials: M
authors.lastname: Posada-de la Paz
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis*; D057189:Checklist; D002675:Child, Preschool; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013030:Spain