title: [Clinical efficacy of vardenafil on ED patients with kidney-yang or -yin deficiency or liver-qi stasis].
abstract: OBJECTIVE
  To study the clinical efficacy of vardenafil on erectile dysfunction (ED) patients with kidney-yang deficiency, kidney-yin deficiency or liver-qi stasis.
  
  
  METHODS
  Based on the syndromes of Traditional Chinese Medicine, 124 ED patients were divided into Groups A (kidney-yang deficiency, n=44), B (kidney-yin deficiency, n=41) and C (liver-qi stasis, n = 39). All the patients were treated with vardenafil at 5 mg daily for 8 weeks, and the therapeutic effects were evaluated by comparing the scores on IIEF-5 and Erection Quality Scale (EQS) before and after the treatment.
  
  
  RESULTS
  After vardenafil treatment, the IIEF-5 and EQS scores of the ED patients were markedly increased, with statistically significant differences among the three groups (P < 0.01). The success rate of sexual intercourse was significantly improved in Groups A, B (P < 0.01) and C (P < 0.05). And the hardness of penile erection was enhanced by 81.82%, 73.17% and 43.59% respectively in the three groups of patients.
  
  
  CONCLUSIONS
  Vardenafil is more effective for ED patients with kidney-yang or kidney-yin deficiency than for those with liver-qi stasis.
authors.affiliation: Nanchang Hospital of Andrology/ Nanchang Institute of Medical Science, Nanchang, Jiangxi 330001, China. stutian@163.com
authors.forename: He-ping
authors.initials: HP
authors.lastname: Xu
authors.forename: Er-po
authors.initials: EP
authors.lastname: Tian
authors.forename: Jie
authors.initials: J
authors.lastname: Xue
authors.forename: Ming-liang
authors.initials: ML
authors.lastname: Zhang
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D013450:Sulfones / Q000627:therapeutic use; D014227:Triazines / Q000627:therapeutic use; D000069058:Vardenafil Dihydrochloride; D014665:Vasodilator Agents / Q000627:therapeutic use*; D016711:Yang Deficiency / Q000188:drug therapy; D016710:Yin Deficiency / Q000188:drug therapy
chemical_list: D007093:Imidazoles; D010879:Piperazines; D013450:Sulfones; D014227:Triazines; D014665:Vasodilator Agents; D000069058:Vardenafil Dihydrochloride