title: Effect of anterior cruciate ligament reconstruction on biomechanical features of knee in level walking: a meta-analysis.
abstract: BACKGROUND
  The anterior cruciate ligament (ACL) is one of the most commonly injured knee ligaments. Even following ACL reconstruction, significant articular cartilage degeneration can be observed and most patients suffer from premature osteoarthritis. Articular cartilage degeneration and osteoarthritis development after ACL injury are regarded as progressive process that are affected by cyclic loading during frequently performed low-intensity daily activities. The purpose of this study was to perform a meta analysis on studies assessing the effects of ACL reconstruction on kinematics, kinetics and proprioception of knee during level walking.
  
  
  METHODS
  This meta analysis was conducted according to the methodological guidelines outlined by the Cochrane Collaboration. An electronic search of the literature was performed and all trials published between January 1966 and July 2010 comparing gait and proprioception of a reconstructed-ACL group with an intact-ACL group were pooled for this review. Thirteen studies were included in the final meta analysis.
  
  
  RESULTS
  There was no significant difference in step length, walking speed, maximum knee flexion angle during loading response, joint position sense and threshold to detect passive motion between the reconstructed-ACL group and the intact-ACL group (P > 0.05). However, there was a significant difference in peak knee flexion angle, maximum angular knee flexion excursion during stance, peak knee flexion moment during walking and maximum external tibial rotation angle throughout the gait cycle between the reconstructed-ACL group and the intact-ACL group (P < 0.05).
  
  
  CONCLUSIONS
  Step length, walking speed, maximum knee flexion angle during loading response, joint position sense and threshold to detect passive motion usually observed with ACL deficiency were restored after the ACL reconstruction and rehabilitation, but no significant improvements were observed for peak knee flexion angle, maximum angular knee flexion excursion during stance, peak knee flexion moment during walking and maximum external tibial rotation angle throughout the gait cycle.
authors.affiliation: Department of Sports Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
authors.forename: Dong-Liang
authors.initials: DL
authors.lastname: Shi
authors.forename: Yu-Bin
authors.initials: YB
authors.lastname: Wang
authors.forename: Zi-Sheng
authors.initials: ZS
authors.lastname: Ai
mesh_terms: D016118:Anterior Cruciate Ligament / Q000601:surgery*; D001696:Biomechanical Phenomena; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D016138:Walking / Q000502:physiology*