title: Partial mastectomy and m. latissimus dorsi reconstruction for radiation-induced fibrosis after breast-conserving cancer therapy.
abstract: BACKGROUND
  Patients with severe complaints of radiation-induced fibrosis after breast-conserving therapy and not responding to conservative therapy, were treated by partial mastectomy and m. latissimus dorsi reconstruction.
  
  
  METHODS
  To determine the feasibility and outcome of this approach, a retrospective study of nine patients was carried out.
  
  
  RESULTS
  After a mean follow-up of 46 months, eight of the nine patients experienced improvement of their complaints and shape of the breast. In only one case did the procedure fail, as evidenced by continuation of all complaints.
  
  
  CONCLUSIONS
  Partial mastectomy and m. latissimus dorsi reconstruction is the ultimate option in the treatment of radiation fibrosis. The procedure is safe with satisfying results.
authors.affiliation: Department of Surgical Oncology, Erasmus Medical Center/Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, Netherlands. a.n.vangeel@erasmusmc.nl
authors.forename: Albertus N
authors.initials: AN
authors.lastname: van Geel
authors.forename: Titia E
authors.initials: TE
authors.lastname: Lans
authors.forename: Roel
authors.initials: R
authors.lastname: Haen
authors.forename: Rudi
authors.initials: R
authors.lastname: Tjong Joe Wai
authors.forename: Marian B E
authors.initials: MB
authors.lastname: Menke-Pluijmers
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D004954:Esthetics; D005260:Female; D005355:Fibrosis / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D016462:Mammaplasty / Q000379:methods; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation*; D011832:Radiation Injuries / Q000473:pathology / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012086:Reoperation / Q000379:methods; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome