title: Liquid chromatography/electrospray time-of-flight mass spectrometry for the characterisation of cyclic phosphazenes.
abstract: Cyclic phosphazenes with different substituents were synthesised and investigated by liquid chromatography (LC) and electrospray ionisation mass spectrometry (ESI-MS). Hexachlorocyclotriphosphazene was functionalised with aliphatic substituents as alcohols and amines, leading to product mixtures, which were subsequently analysed. In contrast to classical methods of structural analysis such as nuclear magnetic resonance (NMR) spectroscopy or X-ray crystallography, which are restricted to pure compounds, these complex mixtures can favourably be analysed by means of LC/ESI-MS. The main products could be separated from by-products and, moreover, all the components of the unknown mixture were unambiguously identified by accurate mass measurements. For all compounds with different side-chain ratios, remaining chlorine atoms or hydroxyl groups and even for spiro or ansa products, molecular structures could be suggested.
authors.affiliation: Westfälische Wilhelms-Universität Münster, Institut für Anorganische und Analytische Chemie, NRW Graduate School of Chemistry, Corrensstraße 30, 48149 Münster, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Veldboer
authors.forename: Thomas
authors.initials: T
authors.lastname: Schürmann
authors.forename: Martin
authors.initials: M
authors.lastname: Vogel
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Wiemhöfer
authors.forename: Uwe
authors.initials: U
authors.lastname: Karst
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008970:Molecular Weight; D010753:Phosphoranes / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D010753:Phosphoranes