title: Seizure in people with newly diagnosed active or transitional neurocysticercosis.
abstract: OBJECTIVE
  The aim of this study is to describe seizure as a presenting symptom in individuals with recently diagnosed neurocysticercosis (NCC).
  
  
  METHODS
  Using logistic regression, we examined the probability of having seizures as a presenting symptom among those with active or transitional NCC by host age and gender, and by number of cysts, location of the cysts in the brain, and phase of evolution of the encysted parasite.
  
  
  RESULTS
  We found that the odds of having seizures as presenting symptom for those in the youngest age group (3-24 years old) were 12.9 times that of the oldest participants (age 55-82 years) (p=0.006). People with cysts in parenchymal locations had a significantly higher odds of seizures compared to those with all their cysts elsewhere (ventricles or subarachnoid) (OR=6.2, p=0.028); and the number of cysts was significantly associated with having seizures (OR=1.1, p=0.026). Host gender and cyst phase were not significantly associated with having seizures after adjusting for confounders and covariates.
  
  
  CONCLUSIONS
  Children, those with cysts in parenchymal locations, and those with a higher number of cysts appear to be more likely to experience seizure when they have NCC cysts in the active or transitional stage.
authors.affiliation: Epidemiology and Biostatistics Track, Urban Public Health Program, CUNY School of Public Health at Hunter College, 425 East 25 St, Room 823W, New York, NY 10010, USA. ekelvin@hunter.cuny.edu
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Kelvin
authors.forename: Arturo
authors.initials: A
authors.lastname: Carpio
authors.forename: Emilia
authors.initials: E
authors.lastname: Bagiella
authors.forename: Denise
authors.initials: D
authors.lastname: Leslie
authors.forename: Pietro
authors.initials: P
authors.lastname: Leon
authors.forename: Howard
authors.initials: H
authors.lastname: Andrews
authors.forename: W Allen
authors.initials: WA
authors.lastname: Hauser
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020019:Neurocysticercosis / Q000150:complications* / Q000473:pathology*; D016032:Randomized Controlled Trials as Topic; D012640:Seizures / Q000209:etiology*; D055815:Young Adult