title: A computational fluid dynamics study pre- and post-stent graft placement in an acute type B aortic dissection.
abstract: OBJECTIVE
  To demonstrate the capability of computational fluid dynamics (CFD) for quantifying hemodynamic forces pretreatment/posttreatment in type B aortic dissection (TB-AD).
  
  
  METHODS
  From CFD simulations initialized with dynamic magnetic resonance image data, wall shear stress (WSS) and dynamic pressure (dynP) changes post endovascular treatment were quantified.
  
  
  RESULTS
  After 1 year follow-up, thoracic aortic segment was completely remodeled, and persistent, nonthrombosed false lumen in the abdominal aorta was noted. Pretreatment, large WSS (>5 Pa) and dynP (>80 Pa) occurred at entrance tear and a stenotic region in the true lumen (TL). Posttreatment, WSS was lower than 3.3 Pa and dynP was lower than 55 Pa in TL, except at proximal end of the stent graft and at reentrance tear. Two focal locations of high dynP existed within the stent graft.
  
  
  CONCLUSIONS
  Computational fluid dynamics may provide quantitative assessment of hemodynamic wall forces in TB-AD potentially of interest for follow-up examinations.
authors.affiliation: The Methodist Hospital Neurological Institute, Houston, TX, USA. ckarmonik@tmhs.org
authors.forename: Christof
authors.initials: C
authors.lastname: Karmonik
authors.forename: Jean
authors.initials: J
authors.lastname: Bismuth
authors.forename: Mark G
authors.initials: MG
authors.lastname: Davies
authors.forename: Dipan J
authors.initials: DJ
authors.lastname: Shah
authors.forename: Houssam K
authors.initials: HK
authors.lastname: Younes
authors.forename: Alan B
authors.initials: AB
authors.lastname: Lumsden
mesh_terms: D000784:Aortic Dissection / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D003198:Computer Simulation; D057510:Endovascular Procedures / Q000295:instrumentation; D006439:Hemodynamics; D006801:Humans; D057446:Hydrodynamics; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D011312:Pressure; D011474:Prosthesis Design; D015607:Stents; D013314:Stress, Mechanical; D013997:Time Factors; D016896:Treatment Outcome