title: [Case of SAPHO syndrome with significant sternocostoclavicular hyperostosis].
abstract: A 59-year-old man with hypertension developed general fatigue, fever, and precordialgia in early March 2007. An antibacterial agent was intravenously administered; however, no improvement in his symptoms or laboratory findings was observed. He had acne and pustulosis, and radiographs and CT of the chest revealed sternocostoclavicular hyperostosis. As a result, the diagnosis was revised to SAPHO syndrome, and he improved with steroid administration. SAPHO syndrome is a condition that is rarely found at the initial examination in the Department of Internal Medicine. We report a case with a discussion of the literature.
authors.affiliation: Center for Respiratory Diseases, Kawasaki Medical School, Kawasaki Hospital.
authors.forename: Fumiyo
authors.initials: F
authors.lastname: Nanba
authors.forename: Toshikiyo
authors.initials: T
authors.lastname: Hayashi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Ishiga
authors.forename: Michihiro
authors.initials: M
authors.lastname: Kishimoto
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yagi
authors.forename: Niro
authors.initials: N
authors.lastname: Okimoto
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D015218:Hyperostosis, Sternocostoclavicular / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D020551:Pulse Therapy, Drug; D011877:Radionuclide Imaging; D013247:Sternoclavicular Joint / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D011239:Prednisolone; D008775:Methylprednisolone