title: Which medication do I need to manage dizzy patients?
abstract: Vertigo and dizziness are not independent disease entities, but instead symptoms of various diseases. Accordingly, a variety of treatment approaches are required. Here we review the most relevant drugs for managing dizziness, vertigo, and nystagmus syndromes. It is important to differentiate symptomatic treatment of nausea and vomiting with, for example, dimenhydrinate and benzodiazepines, and prophylactic treatment of motion sickness with scopolamine from a causal therapy of the underlying disorders. Examples of such causal therapy include aminopyridines for downbeat nystagmus and episodic ataxia type 2; carbamazepine for vestibular paroxysmia, paroxsymal dysarthria and ataxia in multiple sclerosis, and superior oblique myokymia; betahistine, dexamethasone, and gentamicin for Menière's disease; gabapentin and memantine for different forms of acquired and congenital nystagmus; corticosteroids for acute vestibular neuritis and Cogan's syndrome; metoprolol and topiramate for vestibular migraine; and selective serotonin reuptake inhibitors such as paroxetine for phobic postural vertigo. The clinical entities are briefly described, the various medications are discussed in alphabetical order, and dosage, major side effects, contraindications, and alternative medications of each drug are displayed in boxes for easy reference.
authors.affiliation: Institute of Clinical Neurosciences, University of Munich, Germany. doreen.huppert@med.uni-muenchen.de
authors.forename: Doreen
authors.initials: D
authors.lastname: Huppert
authors.forename: Michael
authors.initials: M
authors.lastname: Strupp
authors.forename: Harald
authors.initials: H
authors.lastname: Mückter
authors.forename: Thomas
authors.initials: T
authors.lastname: Brandt
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D004244:Dizziness / Q000188:drug therapy*; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D013577:Syndrome; D014717:Vertigo / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000927:Anticonvulsants; D006633:Histamine Antagonists