title: Guillain-Barre syndrome associated with peginterferon alfa-2a for chronic hepatitis C: A case report.
abstract: The recommended therapy for chronic hepatitis C (CHC) infection is the combination of a Pegylated interferon and Ribavirin. Almost all such patients on combination therapy experience one or more adverse events during the course of treatment. Significant neurological side effects are rare. A few cases of Bell's Palsy, chronic inflammatory demyelinating polyneuropathy and even one case of acute demyelinating polyneuropathy with atypical features for Guillain-Barre syndrome (GBS) associated with Interferon therapy have been reported but no report of GBS with typical features has been published. We present a case report of typical GBS associated with Peginterferon alfa-2a and Ribavirin used for treatment of CHC infection.
authors.affiliation: Mumtaz A Niazi, Ashaur Azhar, Kashif Tufail, Eyob L Feyssa, Marlene McGregory, Victor Araya, Jorge A Ortiz, Center for Liver Disease and Transplantation, Albert Einstein Healthcare Network, Philadelphia, PA 19141, United States.
authors.forename: Mumtaz A
authors.initials: MA
authors.lastname: Niazi
authors.forename: Ashaur
authors.initials: A
authors.lastname: Azhar
authors.forename: Kashif
authors.initials: K
authors.lastname: Tufail
authors.forename: Eyob L
authors.initials: EL
authors.lastname: Feyssa
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Penny
authors.forename: Marlene
authors.initials: M
authors.lastname: McGregory
authors.forename: Victor
authors.initials: V
authors.lastname: Araya
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Ortiz