title: Studying cancer-related fatigue: report of the NCCN scientific research committee.
abstract: NCCN convened a committee of experts to make recommendations for future studies of cancer-related fatigue (CRF). The committee reviewed the current data on the incidence, clinical measurement, and treatment of CRF. The assessment of fatigue is largely derived from self-report questionnaires that address the symptom of fatigue, and do not correlate the presence of fatigue with change in physical activity. The committee developed a self-report questionnaire, NCCN Fatigue and Contributing Factors Inventory, which incorporates assessments of fatigue, pain, difficulty sleeping, distress, physical activity, and concurrent medications. A clinical research study using this measure in conjunction with the NCCN Breast Cancer Outcomes Database Project is planned. The committee noted a strong interaction among fatigue, pain, difficulty sleeping, and distress and recommended that future clinical research address these interactions.
authors.affiliation: City of Hope Comprehensive Cancer Center, Los Angeles, California, USA. JMortimer@coh.org
authors.forename: Joanne E
authors.initials: JE
authors.lastname: Mortimer
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Barsevick
authors.forename: Charles L
authors.initials: CL
authors.lastname: Bennett
authors.forename: Ann M
authors.initials: AM
authors.lastname: Berger
authors.forename: Charles
authors.initials: C
authors.lastname: Cleeland
authors.forename: Shannon R
authors.initials: SR
authors.lastname: DeVader
authors.forename: Carmen
authors.initials: C
authors.lastname: Escalante
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Gilreath
authors.forename: Arti
authors.initials: A
authors.lastname: Hurria
authors.forename: Tito R
authors.initials: TR
authors.lastname: Mendoza
authors.forename: Hope S
authors.initials: HS
authors.lastname: Rugo
mesh_terms: D000367:Age Factors; D005221:Fatigue / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D009369:Neoplasms / Q000150:complications*