title: Chemical constitution, physical properties, and biocompatibility of experimentally manufactured Portland cement.
abstract: BACKGROUND
  An experimental Portland cement was manufactured with pure raw materials under controlled laboratory conditions. The aim of this study was to compare the chemical constitution, physical properties, and biocompatibility of experimentally manufactured Portland cement with those of mineral trioxide aggregate (MTA) and Portland cement.
  
  
  METHODS
  The composition of the cements was determined by scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDAX). The setting time and compressive strength were tested. The biocompatibility was evaluated by using SEM and XTT assay.
  
  
  RESULTS
  SEM and EDAX revealed the experimental Portland cement to have a similar composition to Portland cement. The setting time of the experimental Portland cement was significantly shorter than that of MTA and Portland cement. The compressive strength of the experimental Portland cement was lower than that of MTA and Portland cement. The experimental Portland cement showed a similar biocompatibility to MTA.
  
  
  CONCLUSIONS
  The experimental Portland cement might be considered as a possible substitute for MTA in clinical usage after further testing.
authors.affiliation: Department of Conservative Dentistry, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, Korea.
authors.forename: Yun-Chan
authors.initials: YC
authors.lastname: Hwang
authors.forename: Do-Hee
authors.initials: DH
authors.lastname: Kim
authors.forename: In-Nam
authors.initials: IN
authors.lastname: Hwang
authors.forename: Sun-Ju
authors.initials: SJ
authors.lastname: Song
authors.forename: Yeong-Joon
authors.initials: YJ
authors.lastname: Park
authors.forename: Jeong-Tae
authors.initials: JT
authors.lastname: Koh
authors.forename: Ho-Hyun
authors.initials: HH
authors.lastname: Son
authors.forename: Won-Mann
authors.initials: WM
authors.lastname: Oh
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry / Q000494:pharmacology; D000704:Analysis of Variance; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D017610:Calcium Compounds / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D019245:Compressive Strength; D003738:Dental Cements / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004338:Drug Combinations; D006801:Humans; D010011:Osteocytes / Q000187:drug effects*; D010087:Oxides / Q000737:chemistry* / Q000494:pharmacology; D012387:Root Canal Filling Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D017640:Silicates / Q000737:chemistry / Q000494:pharmacology
chemical_list: D017607:Aluminum Compounds; D001672:Biocompatible Materials; D017610:Calcium Compounds; D003738:Dental Cements; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C472247:accelerated Portland cement; C086631:mineral trioxide aggregate