title: Non-neoplastic salivary gland lesions: a 15-year study.
abstract: The spectrum of salivary gland lesions is wide and the relative incidence of neoplastic versus non-neoplastic lesions is variable in different studies. A series of non-neoplastic salivary gland lesions is reviewed to analyze their spectrum and their relative frequency. This is a retrospective study of salivary gland excisions and biopsies received in our department from January 1994 to December 2008. Routine hematoxylin and eosin-stained sections of all the salivary gland excisions and biopsies received were analyzed. Of the 393 salivary gland excisions and biopsies received, 216 cases were reported as non-neoplastic (55%) and formed our study group; 177 (45%) were neoplastic. Non-neoplastic lesions were more frequent in major salivary glands (65.7%) and submandibular gland was the most commonly involved (66.2%). Lip was the most frequent site (81.7%) for minor salivary gland lesions. Inflammation was the predominant pathological finding (49.5%), of which non-specific chronic sialadenitis constituted the majority (86.9%). Sialolithiasis was present in 22 cases (20.6%); all of these cases were of non-specific chronic sialadenitis. Cysts were second in frequency (36.6%), of which mucocele was the most common (54.5%). There were 5.6% cases of benign lympho-epithelial lesions, while normal salivary gland tissue was seen in 6.5% cases. Non-neoplastic salivary gland diseases are more common than neoplastic diseases and have a wide disease spectrum.
authors.affiliation: Department of Pathology, Govt. Medical College and Hospital, Sarai Building, Sector-32A, Chandigarh, 160 030, India.
authors.forename: Harsh
authors.initials: H
authors.lastname: Mohan
authors.affiliation: Department of Pathology, Govt. Medical College and Hospital, Sarai Building, Sector-32A, Chandigarh, 160 030, India. tahlananita@yahoo.co.in.
authors.forename: Anita
authors.initials: A
authors.lastname: Tahlan
authors.affiliation: Department of Pathology, Govt. Medical College and Hospital, Sarai Building, Sector-32A, Chandigarh, 160 030, India.
authors.forename: Irneet
authors.initials: I
authors.lastname: Mundi
authors.affiliation: Department of Pathology, Govt. Medical College and Hospital, Sarai Building, Sector-32A, Chandigarh, 160 030, India.
authors.forename: R P S
authors.initials: RPS
authors.lastname: Punia
authors.affiliation: Department of ENT-Head & Neck Surgery, Govt. Medical College and Hospital, Sarai Building, Sector-32A, Chandigarh, 160 030, India.
authors.forename: Arjun
authors.initials: A
authors.lastname: Dass
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012466:Salivary Gland Diseases / Q000175:diagnosis*; D012469:Salivary Glands / Q000473:pathology*; D013997:Time Factors; D055815:Young Adult