title: Antihyperglycemic activity of Tectona grandis Linn. bark extract on alloxan induced diabetes in rats.
abstract: Tectona Grandis Linn.(saag - tick wood), an indigenous medicinal plant, has a folk reputation among the Indian herbs as a hypoglycemic agent. The present study was carried out to evaluate the anti-hyperglycemic effect of T. grandis Linn. bark extract in control and alloxan-diabetic rats. Oral administration of the bark suspension of T. grandis (2.5 and 5 g/kg body wt.) for 30 days resulted in a significant reduction in blood glucose (from 250 ± 6.5 to 50 ± 2.5 mg/dL). Thus, the present study clearly shows that the T. grandis Linn. bark extract exerts anti-hyperglycemic activity.
authors.affiliation: Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha - 402 102, India.
authors.forename: S B
authors.initials: SB
authors.lastname: Varma
authors.forename: D L
authors.initials: DL
authors.lastname: Jaybhaye