title: [Ages of sitting up and walking in preterm newborns less than 1,500 G with bronchopulmonary dysplasia].
abstract: BACKGROUND
  Adverse neurological events in very low birth weight (VLBW) children with bronchopulmonary dysplasia (BPD) are more frequent than in children without. An understanding of the ages when preterm infants acquire certain motor skills will give parents more appropriate information on motor development. The objective of the present study is to estimate the influence between BPD and the age of acquisition of sitting unsupported and independent walking in VLBW children with normal neurological examination at 2 years of corrected age.
  
  
  METHODS
  A longitudinal study was conducted on a cohort of 885 children with VLBW, admitted to the Hospital "12 de Octubre" between January 1991 and December 2003. Age for both skills was established by interview with parents. Means were compared with t-test and Bonferroni adjustment where appropriate.
  
  
  RESULTS
  Both motor skills were acquired later in the group with BPD (7.8±2m vs. 7.1±1.3m for sitting unsupported and 14.5±3.8m vs. 13.4±2.5m for walking) (P<.001). BPD was associated with delayed acquisition (above p90) of these skills, OR=2.6 (1.6-4.1) for sitting and OR=2.8 (1.6-4.8) for walking. Association was found after adjusting for gestational age (GA) and weight.
  
  
  CONCLUSIONS
  BPD was associated with delayed acquisition of both skills in VLBW children with normal neurological examination at 2 years.
authors.affiliation: Departamento de Neonatología, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Marín Gabriel
authors.forename: E
authors.initials: E
authors.lastname: Bergón Sendín
authors.forename: A
authors.initials: A
authors.lastname: Melgar Bonís
authors.forename: N
authors.initials: N
authors.lastname: García Lara
authors.forename: C
authors.initials: C
authors.lastname: Rosa Pallás Alonso
authors.forename: J
authors.initials: J
authors.lastname: de la Cruz Bértolo
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000254:growth & development*; D008137:Longitudinal Studies; D008297:Male; D009043:Motor Activity; D009460:Neurologic Examination; D016138:Walking