title: Rhodium-catalyzed anti-Markovnikov intermolecular hydroalkoxylation of terminal acetylenes.
abstract: We report here the first transition-metal-catalyzed anti-Markovnikov intermolecular hydroalkoxylation of terminal acetylenes to give enol ethers in high yields without using bases. Arylacetylenes as well as alkenyl- and alkylacetylenes were coupled with aliphatic alcohols, and the products were obtained with high Z selectivity in most cases. Effective catalysts were 8-quinolinolato rhodium complexes, which are structurally simple but have been relatively unexplored as catalysts.
authors.affiliation: Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Kondo
authors.forename: Takuya
authors.initials: T
authors.lastname: Kochi
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Kakiuchi