title: Chemical priming for spinal cord injury: a review of the literature. Part I-factors involved.
abstract: BACKGROUND
  There are significant differences between the propensity of neural regeneration between the central and peripheral nervous systems.
  
  
  METHODS
  Following a review of the literature, we describe the role of growth factors, guiding factors, and neurite outgrowth inhibitors in the physiology and development of the nervous system as well as the pathophysiology of the spinal cord. We also detail their therapeutic role as well as those of other chemical substances that have recently been found to modify regrowth following cord injury.
  
  
  CONCLUSIONS
  Multiple factors appear to have promising futures for the possibility of improving spinal cord injury following injury.
authors.affiliation: Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AR, USA.
authors.forename: Martin M
authors.initials: MM
authors.lastname: Mortazavi
authors.forename: Ketan
authors.initials: K
authors.lastname: Verma
authors.forename: Aman
authors.initials: A
authors.lastname: Deep
authors.forename: Fatemeh B
authors.initials: FB
authors.lastname: Esfahani
authors.forename: Patrick R
authors.initials: PR
authors.lastname: Pritchard
authors.forename: R Shane
authors.initials: RS
authors.lastname: Tubbs
authors.forename: Nicholas
authors.initials: N
authors.lastname: Theodore
mesh_terms: D000818:Animals; D006801:Humans; D009414:Nerve Growth Factors / Q000378:metabolism / Q000494:pharmacology; D009416:Nerve Regeneration / Q000187:drug effects / Q000502:physiology*; D013119:Spinal Cord Injuries
chemical_list: D009414:Nerve Growth Factors