title: Terminology, concepts, and models in genetic epidemiology.
abstract: Genetic epidemiology brings together approaches and techniques developed in mathematical genetics and statistics, medical genetics, quantitative genetics, and epidemiology. In the 1980s, the focus was on the mapping and identification of genes where defects had large effects at the individual level. More recently, statistical and experimental advances have made possible to identify and characterise genes associated with small effects at the individual level. In this chapter, we provide a brief outline of the models, concepts, and terminology used in genetic epidemiology.
authors.affiliation: Health Services Research, School of Health and Related Research, University of Sheffield, Sheffield, UK.
authors.forename: M Dawn
authors.initials: MD
authors.lastname: Teare
authors.forename: Mauro F Santibàñez
authors.initials: MF
authors.lastname: Koref
mesh_terms: D020090:Chromosome Segregation / Q000235:genetics; D005190:Family; D005828:Genetics, Population; D006801:Humans; D040582:Inheritance Patterns / Q000235:genetics; D008957:Models, Genetic; D017720:Molecular Epidemiology / Q000379:methods*; D010641:Phenotype; D009626:Terminology as Topic