title: A new technique for management of intercavernous sinus bleeding with titanium clips in transsphenoidal surgery.
abstract: BACKGROUND
  Venous bleeding induced by intercavernous sinus injury during sellar dural opening is a challenging intraoperative complication and is difficult to treat in transsphenoidal surgery. To date, few studies concerning the management of intercavernous sinus bleeding have been reported.
  
  
  OBJECTIVE
  Our aim was to assess the clinical outcomes of a new hemostasis technique utilizing nonpenetrating titanium clips for management of intercavernous sinus bleeding.
  
  
  METHODS
  From January 2007 to July 2008, 242 pituitary tumors were operated using a transnasal transsphenoidal approach. A new technique involving a specially devised clip applier and titanium clips was used to control venous bleeding in 13 (5.4%) patients who exhibited a prominent intercavernous sinus. All patients were evaluated clinically and radiologically at 9 to 24 months, and postoperative magnetic resonance imaging (MRI) was performed at 3 to 18 months.
  
  
  RESULTS
  No operation was interrupted or aborted due to ineffective bleeding control, and there was no delayed bleeding noted as a complication. No complications related to the use of the device occurred. Imaging studies revealed no evidence of significant clip artifact.
  
  
  CONCLUSIONS
  Our surgical experience has revealed that this new hemostasis technique can be a safe, rapid and effective method for control of intercavernous sinus bleeding during sellar dural opening in transsphenoidal surgery. However, a further prospective study to evaluate this method more fully is planned.
authors.affiliation: Department of Neurosurgery, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Hong
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
authors.forename: Songxue
authors.initials: S
authors.lastname: Guo
authors.forename: Jun
authors.initials: J
authors.lastname: Yu
authors.forename: Qun
authors.initials: Q
authors.lastname: Wu
authors.forename: Jianmin
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002426:Cavernous Sinus / Q000601:surgery; D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000601:surgery*; D006488:Hemostasis, Surgical / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D010254:Paranasal Sinus Diseases / Q000209:etiology* / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery; D013100:Sphenoid Bone / Q000601:surgery