title: [Heat injury induced apoptosis in rat striatum neurons].
abstract: OBJECTIVE
  To investigate the effect of hyperthermia on apoptosis of cultivated striatum neurons in the rat.
  
  
  METHODS
  After 30 min hyperthermia in 43 degrees, the Ca2+ concentration, the mitochondria membrane potential of the neuron were detected by Laser Scanning Confocal Microscopy (LSCM). The apoptosis of striatum neurons was detected by TUNEL staining.
  
  
  RESULTS
  Heat stress at 43 degrees C for 40 min caused an increase in the Ca2+ concentration of striatum neurons and a decrease in the mitochondria membrane potential of the striatum neurons.
  
  
  CONCLUSIONS
  The striatum shows more apoptosis neurons after heat stress.
authors.affiliation: Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China.
authors.forename: Wen-Hong
authors.initials: WH
authors.lastname: Fan
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.forename: Lu-Ming
authors.initials: LM
authors.lastname: Wang
authors.forename: Ming
authors.initials: M
authors.lastname: Fan
authors.forename: Cheng
authors.initials: C
authors.lastname: Xing
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D017209:Apoptosis; D002478:Cells, Cultured; D003342:Corpus Striatum / Q000166:cytology*; D018869:Heat-Shock Response; D006358:Hot Temperature / Q000009:adverse effects; D053078:Membrane Potential, Mitochondrial; D009474:Neurons / Q000166:cytology* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar