title: Extending limits of resection for metastatic colorectal cancer: risk benefit ratio.
abstract: Improvements in treatment strategies and a better knowledge of tumor biology have contributed to an increase in the number of patients with colorectal liver metastases (CLM) who are candidate for surgery. These progresses are on going and the introduction of effective systemic therapy agents contributes further to the increase in the resectability of patients with advanced CLM.
authors.affiliation: Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Yang
authors.forename: Antoine
authors.initials: A
authors.lastname: Brouquet
authors.forename: Jean Nicolas
authors.initials: JN
authors.lastname: Vauthey
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000503:physiopathology / Q000556:secondary / Q000601:surgery* / Q000628:therapy; D018570:Risk Assessment
chemical_list: D000970:Antineoplastic Agents