title: Multidisciplinary management in rectal cancer.
abstract: The treatment of rectal cancer has evolved over the last few decades from surgery alone to treatments with trimodal therapy for high-risk patients. The involvement of a multidisciplinary team of radiologists, pathologists, surgeons, radiotherapists and medical oncologists is now fundamental for decision-making and outcomes. The evolution of different diagnostic and therapeutic techniques has optimised the therapeutic rate. Future studies will determine the optimal regimen for inducing complete responses in locally advanced disease and whether the intensification of local treatments could enable the use of more conservative treatments, as for other tumour locations. The study of biomarkers will be essential in this respect.
authors.affiliation: Oncology Radiotherapy Department, Hospital Ramón y Cajal, Madrid, Spain. ahervas.hrc@salud.madrid.org
authors.forename: Asunción
authors.initials: A
authors.lastname: Hervás Morón
authors.forename: María Luisa
authors.initials: ML
authors.lastname: García de Paredes
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lobo Martínez
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D019468:Disease Management; D006801:Humans; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012004:Rectal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic