title: [MicroRNAs and prostate cancer].
abstract: MicroRNAs (miRNAs), with the length of about 22 nucleotides, are a growing family of small non-protein-coding RNAs that function as post-transcriptional regulators of target genes, involved in multiple processes of life and closely related with tumorigenesis. Recently, some aberrantly expressed miRNAs have been discovered in the prostate, indicating that miRNA may play a critical role in the molecular mechanism of the pathogenesis of prostate cancer. With deeper studies on human serum and plasma miRNAs, serum miRNA is promising to be a potential diagnostic biomarker for prostate cancer.
authors.affiliation: PLA Research Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China. yanghua_207@163.com
authors.forename: Cui-hua
authors.initials: CH
authors.lastname: Yang
authors.forename: Chun-ni
authors.initials: CN
authors.lastname: Zhang
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D035683:MicroRNAs / Q000235:genetics*; D011471:Prostatic Neoplasms / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; D035683:MicroRNAs