title: Immunotoxicity activity from various organic solvents extract of Allium genus from South Korea against Aedes aegypti L.
abstract: Species of the Allium genus, used in functional foods for the treatment of improving gastritis and heart failures, were collected and petroleum ether, chloroform, and ethyl acetate extracts were obtained by sonication. The Allium thumbergii chloroform extracts have a significant toxic effect against early fourth-stage larvae of Aedes aegypti L. with an LC(50) value of 2.4 μg/mL and an LC(90) value of 6.3 μg/mL. The Allium victorialis var. platyphyllum petroleum ether extracts have a significant toxic effect against early fourth-stage larvae of A. aegypti L. with an LC(50) value of 1.2 μg/mL and an LC(90) value of 2.1 μg/mL. Also, the Allium sacculiferum chloroform extracts have a significant toxic effect against early fourth-stage larvae of A. aegypti L. with an LC(50) value of 1.8 μg/mL and an LC(90) value of 4.7 μg/mL. The above data indicate that major compounds may play a more important role in the toxicity of A. victorialis var. platyphyllum petroleum ether extracts.
authors.affiliation: Department of Herbal Medicine Resources, Kangwon National Universtiy, Samcheok, South Korea.
authors.forename: Jung-Dae
authors.initials: JD
authors.lastname: Lim
authors.forename: Ill-Min
authors.initials: IM
authors.lastname: Chung
authors.forename: Hyung-In
authors.initials: HI
authors.lastname: Moon
mesh_terms: D000330:Aedes; D000473:Alkanes / Q000737:chemistry; D000490:Allium / Q000737:chemistry* / Q000276:immunology; D000818:Animals; D005260:Female; D007306:Insecticides; D007814:Larva / Q000276:immunology / Q000469:parasitology; D007928:Lethal Dose 50; D051379:Mice; D009032:Mosquito Control / Q000379:methods; D010936:Plant Extracts / Q000737:chemistry* / Q000276:immunology / Q000494:pharmacology*; D056910:Republic of Korea
chemical_list: D000473:Alkanes; D007306:Insecticides; D010936:Plant Extracts; C004544:naphtha