title: Bilateral herpes simplex-2 acute retinal necrosis with encephalitis in premature twins.
abstract: Acute retinal necrosis, caused by the herpes family of viruses, is a rapidly progressing ocular inflammatory disorder commonly reported in adults but rarely in children. The accepted diagnostic criteria include presence of 1 or more foci of retinal necrosis, rapid progression, circumferential spread, occlusive vasculopathy, and inflammation in the vitreous and anterior chamber. We report bilateral acute retinal necrosis with encephalitis due to herpes simplex virus (HSV-2) in newborn twins.
authors.affiliation: Srimati Kannuri Santhamma Centre for Vitreo Retinal Diseases, Hyderabad, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Gupta
authors.forename: Padmaja Kumari
authors.initials: PK
authors.lastname: Rani
authors.forename: Bhupesh
authors.initials: B
authors.lastname: Bagga
authors.forename: Padmapriya
authors.initials: P
authors.lastname: Dore
authors.forename: Ashok
authors.initials: A
authors.lastname: Mittal
authors.forename: Subhadra
authors.initials: S
authors.lastname: Jalali
mesh_terms: D000208:Acute Disease; D000212:Acyclovir / Q000008:administration & dosage; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage; D020803:Encephalitis, Herpes Simplex / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D006558:Herpes Genitalis / Q000188:drug therapy / Q000473:pathology / Q000635:transmission*; D018258:Herpesvirus 2, Human; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009336:Necrosis; D012173:Retinitis / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D014427:Twins
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir