title: There's plenty of time for evolution.
abstract: Objections to Darwinian evolution are often based on the time required to carry out the necessary mutations. Seemingly, exponential numbers of mutations are needed. We show that such estimates ignore the effects of natural selection, and that the numbers of necessary mutations are thereby reduced to about K log L, rather than K(L), where L is the length of the genomic "word," and K is the number of possible "letters" that can occupy any position in the word. The required theory makes contact with the theory of radix-exchange sorting in theoretical computer science, and the asymptotic analysis of certain sums that occur there.
authors.affiliation: Department of Mathematics, University of Pennsylvania, Philadelphia, PA 19104-6395, USA. wilf@math.upenn.edu
authors.forename: Herbert S
authors.initials: HS
authors.lastname: Wilf
authors.forename: Warren J
authors.initials: WJ
authors.lastname: Ewens
mesh_terms: D000465:Algorithms; D000818:Animals; D019143:Evolution, Molecular; D006801:Humans; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics*; D012641:Selection, Genetic; D013997:Time Factors