title: Noxa: a sweet twist to survival and more.
abstract: The BCL-2 family member Noxa induces apoptosis by antagonizing the prosurvival protein MCL-1. In this issue of Molecular Cell, Lowman et al. (2010) uncover a glucose-dependent phosphoregulatory mechanism that inactivates Noxa's apoptotic function and triggers its capacity to modulate glucose metabolism.
authors.affiliation: Department of Cancer Biology and Division of Metabolism and Chronic Disease, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Gimenez-Cassina
authors.forename: Nika N
authors.initials: NN
authors.lastname: Danial