title: Protopanaxatriol-type ginsenosides from the root of Panax ginseng.
abstract: Ginseng, the root of Panax ginseng C. A. Meyer (Araliaceae), is one of the most important traditional medicines and functional foods. A detailed phytochemical investigation on the roots of P. ginseng led to the isolation of 6 new natural protopanaxatriol (PPT)-type ginsenosides, ginsenosides Re(1)-Re(6) (compounds 1-6), along with 10 known PPT-type ginsenosides. Their structures were elucidated on the basis of chemical and spectroscopic analyses, including high-resolution mass spectrometry (HRMS) and 1D and 2D nuclear magnetic resonance (NMR). The unusual α-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl sugar chain, as found in compounds 1 and 2, is reported in the genus Panax for the first time.
authors.affiliation: Center for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region (SAR), China.
authors.forename: Guo-Yuan
authors.initials: GY
authors.lastname: Zhu
authors.forename: Ying-Wei
authors.initials: YW
authors.lastname: Li
authors.forename: Desmond Kwok-Po
authors.initials: DK
authors.lastname: Hau
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Jiang
authors.forename: Zhi-Ling
authors.initials: ZL
authors.lastname: Yu
authors.forename: Wang-Fun
authors.initials: WF
authors.lastname: Fong
mesh_terms: D036145:Ginsenosides / Q000737:chemistry*; D015394:Molecular Structure; D005894:Panax / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D012502:Sapogenins / Q000737:chemistry*
chemical_list: D036145:Ginsenosides; D010936:Plant Extracts; D012502:Sapogenins; C081552:protopanaxatriol