title: Lymph node uptake of 18F-fluorodeoxyglucose detected with positron emission tomography/computed tomography mimicking malignant lymphoma in a patient with Kikuchi disease.
abstract: [18]F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is sensitive in detecting a variety of malignancies; however, the specificity is low in differential infections or inflammatory diseases from tumors. We present the case of a female with right cervical lymphadenopathy and fever for 3 weeks who underwent an 18F-FDG PET/CT scan. The imaging showed multiple lymph node enlargement and agglomeration with increased metabolic activity even with the involvement in the abdomen, giving the impression of malignant lymphoma. However, biopsy of the affected nodes proved it to be Kikuchi-Fujimoto disease and the patient was cured after steroid therapy.
authors.affiliation: Division of PET/CT Center, Department of Nuclear Medicine, Huadong Hospital, Fudan University, No. 211 West Yan An Road, Shanghai, China.
authors.forename: Min-jia
authors.initials: MJ
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Xiao
authors.forename: Yu-hua
authors.initials: YH
authors.lastname: Zhu
authors.forename: Jian-jun
authors.initials: JJ
authors.lastname: Jiang
authors.forename: Mao-song
authors.initials: MS
authors.lastname: Jiang
authors.forename: Wei
authors.initials: W
authors.lastname: He
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000378:metabolism; D008223:Lymphoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019788:Fluorodeoxyglucose F18