title: Xenopus embryos and ES cells as tools for studies of developmental biology.
abstract: Nearly 20 years ago Professor Katsuhiko Mikoshiba led me to an exciting world of IP(3)-Ca(2+) signaling, we embarked on the role of IP(3)-Ca(2+) signaling on fertilization, early cell cycle progression, and body axis formation. I was fully enchanted by the world of basic science, particularly developmental biology. It is a great pleasure to contribute a paper to this special issue of Neurochemical Research honoring Professor Katsuhiko Mikoshiba. Many of the former lab members are now working in a wide range of fields, both inside or outside the fields of Neurochemical research. I am one of those who are working in a different field. Therefore, it seems fitting here to first write about our former work with IP3 receptor, and then introduce our recent works.
authors.affiliation: Department of Stem Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan. skume@kumamoto-u.ac.jp
authors.forename: Shoen
authors.initials: S
authors.lastname: Kume
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage; D015509:Developmental Biology; D053595:Embryonic Stem Cells / Q000502:physiology*; D005306:Fertilization / Q000502:physiology; D018398:Homeodomain Proteins / Q000502:physiology; D053496:Inositol 1,4,5-Trisphosphate Receptors / Q000502:physiology*; D051379:Mice; D009865:Oocytes / Q000502:physiology; D010179:Pancreas / Q000196:embryology*; D013234:Stem Cells / Q000502:physiology; D015534:Trans-Activators / Q000502:physiology; D014982:Xenopus laevis
chemical_list: D018398:Homeodomain Proteins; D053496:Inositol 1,4,5-Trisphosphate Receptors; D015534:Trans-Activators; C084010:pancreatic and duodenal homeobox 1 protein; D002118:Calcium