title: [Survival analysis on advanced non-small cell lung cancer with a Buckley-James model].
abstract: OBJECTIVE
  To analyze the risk factors related to survival time of advanced non-small cell lung cancer (NSCLC) and to establish a prediction model on survival time.
  
  
  METHODS
  From 2004 - 2006, 184 patients with advanced NSCLC were enrolled in the Affiliated Hospital to the Nantong Medical College. Related risk factors were analyzed, using the Buckley-James model. Both actual and predicted survival time were compared by log-rank test.
  
  
  RESULTS
  Through Buckley-James model analysis, data showed that KPS, clinical stage, treatment and pre-treatment hemoglobin were main influencing factors on survival time. Regression equation appeared to be lnMONTH=0.0108 KPS+0.0238 HB+0.4614 IIIb+0.8027 IIIa+0.3869 (radiotherapy+chemotherapy)+0.507 (radiotherapy + operation) + 0.6082 (chemotherapy + operation) - 2.098. There was no statistical difference between the prediction and the actual models of survival time by log-rank test (P=0.575>0.05).
  
  
  CONCLUSIONS
  KPS, clinical stage, treatment and pre-treatment hemoglobin might be associated. Both the prognosis of patients with advanced NSCLC and the prediction model seemed to have practical significances.
authors.affiliation: Epidemiology and Health Statistics Department of Public Health College of Nantong University, Nantong 226001, China.
authors.forename: Tian
authors.initials: T
authors.lastname: Xu
authors.forename: Hong-yu
authors.initials: HY
authors.lastname: Zhao
authors.forename: Yu
authors.initials: Y
authors.lastname: Yan
authors.forename: Su-rong
authors.initials: SR
authors.lastname: Wang
authors.forename: Xiang-zhu
authors.initials: XZ
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000401:mortality*; D005260:Female; D006801:Humans; D017567:Karnofsky Performance Status; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D016019:Survival Analysis