title: Atrioventricular nodal reentrant tachycardia treatment using novel potential.
abstract: Radiofrequency ablation of atrioventricular nodal reentrant tachycardia is commonly guided by slow and sharp bipolar potentials of the atrioventricular slow nodal pathway. We optimized the morphology of the guiding potential by unipolar mapping of the slow nodal pathway. We identified a novel unipolar dual-component atrial electrogram at the anterior limb of the coronary sinus ostium. The first component was a positive delta-wave type that corresponded to the isoelectric phase on a bipolar electrogram. The second component had fast biphasic morphology and corresponded to the R wave on a bipolar atrial electrogram. Of 104 consecutive patients with typical atrioventricular nodal reentrant tachycardia, 51 were treated with ablation guided by the novel potential, and 53 underwent ablation using the conventional technique. There was no recurrence of tachycardia in any of these patients. In those treated by the novel potential, there was significantly less radiofrequency power applied and a shorter duration of application than in patients treated by the traditional approach. The novel approach to mapping and ablation of the slow nodal pathway in atrioventricular nodal reentrant tachycardia guided by unipolar recording was safe and effective, and comparable to the traditional technique.
authors.affiliation: Clinical Hospital of Federal Biomedical Agency of Russia, Moscow, Russia. ardashev@yahoo.com
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Ardashev
authors.forename: Alexandr S
authors.initials: AS
authors.lastname: Makarenko
authors.forename: Eugeny G
authors.initials: EG
authors.lastname: Zhelyakov
authors.forename: Andrey A
authors.initials: AA
authors.lastname: Shavarov
mesh_terms: D000200:Action Potentials; D000328:Adult; D016022:Case-Control Studies; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009031:Moscow; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome