title: [A comprehensive prevention programs on AIDS, HBV and syphilis among pregnant women and couples experienced premarital medical examination].
abstract: OBJECTIVE
  To evaluate the effect of comprehensive prevention programs on HIV, HBV and syphilis transmission from mother to child and between premarital couples.
  
  
  METHODS
  HIV, HBV and syphilis were screened among pregnant women with interventional measure for infected women; HIV, HBV and syphilis (TP) were screened among premarital couples with medical advice.
  
  
  RESULTS
  The HIV, HBsAg and TP positive rates were 8.4‰ (111/13 280), 54‰ (711/13 186) and 12.8‰ (159/12 401) respectively among pregnant women and the total positive rate of the three diseases was 73.8‰ which was significantly higher than HIV positive rate (P < 0.001). The positive rates of HIV, HBsAg and TP were 17.6‰ (464/26 324), 95.3‰ (1826/19 152) and 18.6‰ (355/19 099) respectively among premarital couples and the total positive rate of the three diseases was 131.5‰ which was significantly higher than HIV positive rate alone (P < 0.001). Comprehensive prevention was more economical than prevention for HIV alone.
  
  
  CONCLUSIONS
  The comprehensive strategies for prevention of HIV, HBV and syphilis was feasible, effective and economical that could help to actively conduct the preventive measures.
authors.affiliation: Zhongnan Hospital of Wuhan University, Wuhan 430071, China. Email: ZNACT@126.com.
authors.forename: Xi-En
authors.initials: XE
authors.lastname: Gui
authors.forename: Yuan-Zhen
authors.initials: YZ
authors.lastname: Zhang
authors.forename: Rong-Rong
authors.initials: RR
authors.lastname: Yang
authors.forename: Silafu
authors.initials: S
authors.lastname: Rezivan
authors.forename: Feng-Liang
authors.initials: FL
authors.lastname: Li
authors.forename: Ai-Hua
authors.initials: AH
authors.lastname: Qin
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Li-Zhen
authors.initials: LZ
authors.lastname: Wu
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Zong
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D003376:Counseling; D005260:Female; D015658:HIV Infections / Q000175:diagnosis; D006514:Hepatitis B Surface Antigens; D006801:Humans; D011247:Pregnancy; D013587:Syphilis
chemical_list: D006514:Hepatitis B Surface Antigens