title: [Clinical observation on treating diabetic macular edema with intravitreal triamcinolone acetonide and laser].
abstract: OBJECTIVE
  To evaluate the effect of intravitreal injection of triamcinolone acetonide(IVTA) combining with retinal laser treating for diabetic macular edema(DME).
  
  
  METHODS
  Twenty five patients(32 eyes) with DME who has microangioma in macula lutea were randomly divided into group A, B,C and D(8 eyes each group). Eyes in group A were treated with laser photocoagulation. Eyes in group B were treated with multiplier-532 laser photocoagulation and transpupillary thermotherapy. Eyes in group C were treated with multiplier-532 laser photocoagulation and intravitreal triamcinolone acetonide. Eyes in group D were treated with multiplier-532 laser, transpupillary thermotherapy plus triamcinolone acetonide injection. Intravitreal injection of 4 mg triamcinolone acetonide was done 1 week after laser photocoagulation in group C and D. The visual acuity, intraocular pressure, macular thickness (foveal thickness) of the eyes in 4 groups were observed before and 1, 3 and 6 months after treatment.
  
  
  RESULTS
  The visual acuity, intraocular pressure and foveal thickness of the 4 groups before treatment showed no significant difference(p> ). The visual acuity, intraocular pressure, macular thickness of eyes in group A, B were better than those of group C, D at 1, 3 and 6 months after treatment, and they had significant difference(p<0.05), while they didn't show significant difference between group A and B, group C and D(p>0.05).
  
  
  CONCLUSIONS
  The effect of laser photocoagulation and intravitreal triamcinolone acetonide, laser photocoagulation combining with transpupillary thermotherapy plus triamcinolone acetonide injectionvisual treating for DME was better than laser photocoagulation alone, laser photocoagulation combining with transpupillary thermotherapy.
authors.affiliation: Department of Ophthalmology, The Third Affiliated Hospital of Nanchang University, Nanchang.
authors.forename: Yongbo
authors.initials: Y
authors.lastname: Wang
authors.forename: Anna
authors.initials: A
authors.lastname: Shi
authors.forename: Xun
authors.initials: X
authors.lastname: Shi
authors.forename: Weifeng
authors.initials: W
authors.lastname: Liu
mesh_terms: D003930:Diabetic Retinopathy / Q000188:drug therapy; D005938:Glucocorticoids; D006801:Humans; D007267:Injections; D017075:Laser Coagulation; D008269:Macular Edema; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide; D014792:Visual Acuity; D014822:Vitreous Body
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide