title: 68Ga-DOTA-NOC PET/CT detects somatostatin receptors expression in von hippel-lindau cerebellar disease.
abstract: A case of Von-Hippel Lindau (VHL) disease has been studied using 68Ga-DOTA-NOC PET/CT. PET/CT demonstrated the presence of somatostatin receptors within 2 focal areas in the cerebellum corresponding to the lesions detected by MRI. Considering the heterogeneous lesions localizations in VHL disease, PET/CT may be a useful imaging modality for diagnosing lesions of central nervous system and neuroendocrine lesions and for direct demonstration of somatostatin receptors for targeted treatment.
authors.affiliation: Departments of Nuclear Medicine, Azienda Ospedaliero-Universitaria di Bologna, S. Orsola-Malpighi University Hospital, Bologna, Italy. valentina.ambrosini@aosp.bo.it
authors.forename: Valentina
authors.initials: V
authors.lastname: Ambrosini
authors.forename: Davide
authors.initials: D
authors.lastname: Campana
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Allegri
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Opocher
authors.forename: Stefano
authors.initials: S
authors.lastname: Fanti
mesh_terms: D002531:Cerebellum / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D017481:Receptors, Somatostatin / Q000378:metabolism*; D014057:Tomography, X-Ray Computed; D006623:von Hippel-Lindau Disease / Q000000981:diagnostic imaging*
chemical_list: C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D017481:Receptors, Somatostatin