title: Analysis of testosterone in human urine using molecularly imprinted solid-phase extraction and corona discharge ion mobility spectrometry.
abstract: Analysis of testosterone was accomplished using corona discharge ion mobility spectrometry. Molecular imprinted polymer was used for the extraction and pre-concentration of testosterone. Analytical parameters including precision, dynamic range and detection limit were obtained. The linear dynamic range was from 10 to 250 ng/mL and the limit of detection was 0.9 ng/mL. The proposed method was used for analysis of testosterone in urine samples. A urine sample from a 3-year-old girl was used as the blank. The RSD was below 10%. The obtained results from the method were also compared with the standard method for analysis of testosterone using SPE-HPLC analysis. The results demonstrate the accuracy of the method.
authors.affiliation: Department of Chemistry, Isfahan University of Technology, Isfahan, Iran.
authors.forename: Shiva
authors.initials: S
authors.lastname: Mirmahdieh
authors.forename: Azam
authors.initials: A
authors.lastname: Mardihallaj
authors.forename: Zahra
authors.initials: Z
authors.lastname: Hashemian
authors.forename: Jalal
authors.initials: J
authors.lastname: Razavizadeh
authors.forename: Hassan
authors.initials: H
authors.lastname: Ghaziaskar
authors.forename: Taghi
authors.initials: T
authors.lastname: Khayamian
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D057230:Limit of Detection; D008297:Male; D054802:Molecular Imprinting; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013057:Spectrum Analysis / Q000295:instrumentation / Q000379:methods*; D013739:Testosterone / Q000652:urine*
chemical_list: D013739:Testosterone