title: Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?
abstract: Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.
authors.affiliation: Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA.
authors.forename: James
authors.initials: J
authors.lastname: Maylie
authors.forename: John P
authors.initials: JP
authors.lastname: Adelman