title: [Antibiotic susceptibility of Corynebacterium macginleyi strains causing conjunctivitis].
abstract: BACKGROUND
  Lipophilic corynebacteria are part of the saprophytic skin flora and they rarely cause infection. C. macginleyi is an exception since it has been involved in conjunctivitis and other ocular surface affections.
  
  
  METHODS
  Thirty three C. macginleyi strains were obtained from conjunctival swabs from patients with conjunctivitis symptoms. The minimum inhibitory concentration (MIC) for 7 antibiotics (penicillin, gentamycin, ciprofloxacin, tetracycline, vancomycin, rifampicin and linezolid) was tested by broth microdilution method.
  
  
  RESULTS
  One strain was resistant to ciprofloxacin (MIC=16 mg/L) and two were resistant to tetracycline (MIC= 64 y 16 mg/L). The rest of the strains were susceptible to all the antibiotics tested.
  
  
  CONCLUSIONS
  At the moment, C. macginleyi does not present a major problem due to the low resistance rates shown in the present and other studies. However, epidemiological surveillance of its susceptibility pattern is needed as well as an appropriate use of topical antibiotics in order to achieve a good infection control.
authors.affiliation: Servicio de Microbiología, Hospital Universitario de la Princesa, C/ Diego de León 62, 28006, Madrid, Spain. marina_ed@hotmail.com
authors.forename: Marina
authors.initials: M
authors.lastname: Espínola
authors.forename: Angela
authors.initials: A
authors.lastname: Somodevilla
authors.forename: Diego
authors.initials: D
authors.lastname: Domingo
authors.forename: Teresa
authors.initials: T
authors.lastname: Alarcón
authors.forename: Manuel
authors.initials: M
authors.lastname: López-Brea
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D003228:Conjunctiva / Q000382:microbiology; D003231:Conjunctivitis / Q000188:drug therapy / Q000382:microbiology*; D003352:Corynebacterium / Q000187:drug effects*; D003354:Corynebacterium Infections / Q000188:drug therapy / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D005128:Eye Diseases / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013753:Tetracycline Resistance
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin