title: [Antimicrobial consumption reported through standardized reports on infection control activities, relationship with the ICATB public reporting indicator].
abstract: OBJECTIVE
  The study's objective was to describe the evolution of antibiotic consumption between 2006 and 2008 in French health care facilities (HCF) its relations with the national policy of good antibiotics use using the ICATB score.
  
  
  METHODS
  Data from standardized reports on infection control activities collected from 2006 to 2008 by the Ministry of Health (antibiotic consumptions and elements of antibiotic stewardship of every HCF) were analyzed with linear regression models to multilevel random intercept adjusted on HCF characteristics (public or private) and activity.
  
  
  RESULTS
  The analysis was performed on 4062 (48,2%) observations after exclusion of HCF not concerned by the ICATB public reporting indicator (7.2% of observations), invalid or missing data (21,2% of observations) and irrelevant values (23.4%). The global antibiotic consumption was 343 defined daily doses (DDD) per 1000 patient-days (PD) and varied little between 2006 and 2008. However, the linear regression model showed an increase of 5.7 DDD per 1000 PDs per year (P<0.001). There was a positive association between antibiotic consumption and ICATB score, mainly concerning sub-scores ICATB-action and ICATB-organization.
  
  
  CONCLUSIONS
  The recent lack of decrease in antibiotic consumption in French HCF between 2006 and 2008 is coherent with other available national data, but exclusion of more than 50% of observations limits the impact of this analysis. The relationship between policy of good use and consumption of antibiotics remain difficult to specify, because of the short (three years) study length and because of the nature of ICATB, a composite indicator assessing only partly antibiotic policies.
authors.affiliation: Institut de veille sanitaire, Saint-Maurice, France. s.henard@chu-nancy.fr
authors.forename: S
authors.initials: S
authors.lastname: Henard
authors.forename: D
authors.initials: D
authors.lastname: Rahib
authors.forename: L
authors.initials: L
authors.lastname: Léon
authors.forename: B
authors.initials: B
authors.lastname: Amadéo
authors.forename: C
authors.initials: C
authors.lastname: Dumartin
authors.forename: P
authors.initials: P
authors.lastname: Cavalié
authors.forename: B
authors.initials: B
authors.lastname: Coignard
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019985:Benchmarking; D003428:Cross Infection / Q000517:prevention & control; D004282:Documentation / Q000592:standards*; D004363:Drug Utilization / Q000592:standards / Q000706:statistics & numerical data; D005568:Forms and Records Control; D005602:France; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006268:Health Facilities / Q000706:statistics & numerical data*; D006291:Health Policy; D057970:Inappropriate Prescribing / Q000706:statistics & numerical data*; D017053:Infection Control / Q000458:organization & administration*; D008485:Medical Audit; D017410:Practice Guidelines as Topic; D012494:Sampling Studies
chemical_list: D000890:Anti-Infective Agents