title: The HLA-B*83:01 allele is generated by a gene conversion event including whole of exon 2 and partial introns 1 and 2 between B*44 and B*56 alleles.
abstract: Several studies have indicated the gene conversion as the most important mechanism about the MHC polymorphism generation when intron sequences are studied. The data obtained confirm that the B*83:01 allele is generated by gene conversion event including exon 2 and partial intron 1 and 2 between B*44 and B*56 alleles.
authors.affiliation: Inmunoterapia Celular, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Majadahonda, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Cervera
authors.forename: M A
authors.initials: MA
authors.lastname: Herraiz
authors.forename: J A
authors.initials: JA
authors.lastname: Vidart
authors.forename: J
authors.initials: J
authors.lastname: Peñaloza
authors.forename: J
authors.initials: J
authors.lastname: Martinez-Laso
mesh_terms: D001483:Base Sequence; D005091:Exons; D005785:Gene Conversion; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D016415:Sequence Alignment
chemical_list: D015235:HLA-B Antigens