title: HIV-infected adolescents: relationship between atazanavir plasma levels and bilirubin concentrations.
abstract: The use of atazanavir (ATV) in adolescents infected with human immunodeficiency virus was analyzed in this study. ATV morning plasma concentrations were determined during regular visits to the outpatient department. Results showed that bilirubin levels were higher among patients with higher ATV plasma concentrations (p = .018). Monitoring plasma levels of ATV could avoid toxicity in these patients.
authors.affiliation: Servicio de Pediatría, Hospital Infantil La Paz, Madrid, Spain. ananso@yahoo.es
authors.forename: Ana P
authors.initials: AP
authors.lastname: Nso Roca
authors.forename: Ana P
authors.initials: AP
authors.lastname: Nso
authors.forename: Beatriz
authors.initials: B
authors.lastname: Larru
authors.forename: Jose M
authors.initials: JM
authors.lastname: Bellón
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Mellado
authors.forename: Jose T
authors.initials: JT
authors.lastname: Ramos
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: González
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Navarro
authors.forename: Maria Ángeles
authors.initials: MÁ
authors.lastname: Muñoz-Fernández
authors.forename: Maria Isabel de
authors.initials: MI
authors.lastname: José
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services; D019380:Anti-HIV Agents / Q000008:administration & dosage; D000069446:Atazanavir Sulfate; D001663:Bilirubin / Q000097:blood*; D002648:Child; D004334:Drug Administration Schedule; D016903:Drug Monitoring; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy*; D006801:Humans; D006932:Hyperbilirubinemia / Q000517:prevention & control; D008297:Male; D009842:Oligopeptides / Q000008:administration & dosage* / Q000097:blood*; D011725:Pyridines / Q000008:administration & dosage* / Q000097:blood*; D013030:Spain
chemical_list: D019380:Anti-HIV Agents; D009842:Oligopeptides; D011725:Pyridines; D000069446:Atazanavir Sulfate; D001663:Bilirubin