title: 3D visualisation of the stochastic patterns of the radial dose in nano-volumes by a Monte Carlo simulation of HZE ion track structure.
abstract: The description of energy deposition by high charge and energy (HZE) nuclei is of importance for space radiation risk assessment and due to their use in hadrontherapy. Such ions deposit a large fraction of their energy within the so-called core of the track and a smaller proportion in the penumbra (or track periphery). We study the stochastic patterns of the radial dependence of energy deposition using Monte Carlo track structure codes RITRACKS and RETRACKS, that were used to simulate HZE tracks and calculate energy deposition in voxels of 40 nm. The simulation of a (56)Fe(26+) ion of 1 GeV u(-1) revealed zones of high-energy deposition which maybe found as far as a few millimetres away from the track core in some simulations. The calculation also showed that ∼43 % of the energy was deposited in the penumbra. These 3D stochastic simulations combined with a visualisation interface are a powerful tool for biophysicists which may be used to study radiation-induced biological effects such as double strand breaks and oxidative damage and the subsequent cellular and tissue damage processing and signalling.
authors.affiliation: NASA Johnson Space Center, 2101 NASA Parkway, Houston, TX 77058, USA.
authors.forename: Ianik
authors.initials: I
authors.lastname: Plante
authors.forename: Artem
authors.initials: A
authors.lastname: Ponomarev
authors.forename: Francis A
authors.initials: FA
authors.lastname: Cucinotta
mesh_terms: D003196:Computer Graphics; D003198:Computer Simulation; D021621:Imaging, Three-Dimensional; D007477:Ions; D018499:Linear Energy Transfer; D008956:Models, Chemical; D015233:Models, Statistical; D009010:Monte Carlo Method; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D014584:User-Computer Interface
chemical_list: D007477:Ions