title: Comparison of posterolateral thoracotomy and video-assisted thoracoscopic clipping for the treatment of patent ductus arteriosus in neonates and infants.
abstract: This study was designed to compare the long-term clinical outcomes and costs between video-assisted thoracic surgery (VATS) and posterolateral thoracotomy (PT) in neonates and infants. This study enrolled 302 patients with isolated patent ductus arteriosus (PDA) from January 2002 to 2007 and followed them up until April 2010. A total of 134 patients underwent total VATS (VATS group), and 168 underwent PDA closure through PT (PT group). The two groups were compared according to clinical outcomes and costs. The demographics and preoperative clinical characteristics of the patients were similar in the two groups. No cardiac deaths occurred, and the closure rate was 100% successful in both groups. The operating, recovery, and pleural fluid drainage times were significantly shorter in the VATS group than in the PT group. Statistically significant differences in length of incision, postoperative temperature, and acute procedure-related complications were observed between the two groups. The cost was $1,150.3 ± $221.2 for the VATS group and $2415.8 ± $345.2 for the PT group (P < 0.05). No cardiac deaths or newly occurring arrhythmias were detected in either group during the follow-up period. Statistically significant differences in the rate of residual shunt and scoliosis were observed between the two groups. The left ventricular end-diastolic diameter and the pulmonary artery diameter could be restored to normal in the VATS group but not in the PT group. The study confirmed that VATS offers a minimally traumatic, safe, and effective technique for PDA interruption in neonates and infants.
authors.affiliation: Department of Cardiovascular Surgery, Fujian Provincial Hospital, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, People's Republic of China.
authors.forename: Haiyu
authors.initials: H
authors.lastname: Chen
authors.forename: Guoxing
authors.initials: G
authors.lastname: Weng
authors.forename: Zhiqun
authors.initials: Z
authors.lastname: Chen
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Qi
authors.initials: Q
authors.lastname: Xie
authors.forename: Jiayin
authors.initials: J
authors.lastname: Bao
authors.forename: Rongdong
authors.initials: R
authors.lastname: Xiao
mesh_terms: D006348:Cardiac Surgical Procedures / Q000191:economics / Q000379:methods*; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D004374:Ductus Arteriosus, Patent / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D013536:Suture Techniques / Q000295:instrumentation*; D020775:Thoracic Surgery, Video-Assisted / Q000191:economics / Q000379:methods*; D013908:Thoracotomy / Q000191:economics / Q000379:methods*; D016896:Treatment Outcome