title: Complete nucleotide sequence of plasmid pTN48, encoding the CTX-M-14 extended-spectrum β-lactamase from an Escherichia coli O102-ST405 strain.
abstract: The sequence of pTN48, a plasmid of the FII-FIB replicon type that encodes a CTX-M-14 enzyme in an Escherichia coli strain of the phylogenetic group D₂ O102-ST405 clone, was determined. pTN48 is, for the most part, a mosaic of virulence, antibiotic resistance, and addiction system modules found in various other plasmids. The presence of multiple addiction systems indicates that the plasmid should be stably maintained in the E. coli clone, favoring dissemination of the CTX-M-14 enzyme.
authors.affiliation: Service de Microbiologie et Hygiene, Hôpital Louis Mourier, Colombes, France.
authors.forename: Typhaine
authors.initials: T
authors.lastname: Billard-Pomares
authors.forename: Olivier
authors.initials: O
authors.lastname: Tenaillon
authors.forename: Hervé
authors.initials: H
authors.lastname: Le Nagard
authors.forename: Zoé
authors.initials: Z
authors.lastname: Rouy
authors.forename: Stéphane
authors.initials: S
authors.lastname: Cruveiller
authors.forename: Claudine
authors.initials: C
authors.lastname: Médigue
authors.forename: Guillaume
authors.initials: G
authors.lastname: Arlet
authors.forename: Erick
authors.initials: E
authors.lastname: Denamur
authors.forename: Catherine
authors.initials: C
authors.lastname: Branger
mesh_terms: D001483:Base Sequence; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases