title: Invasive fungal rhinitis caused by Paecilomyces lilacinus infection: Report of a case and a novel treatment.
abstract: Invasive fungal infections of the sinonasal tract are a rare but known entity in immunocompromised patients. Paecilomyces lilacinus is a nematophagous fungi with septate hyphae that has afflicted humans in multiple forms, causing cutaneous, ocular, and sinonasal infections. Only 4 cases of P lilacinus and 2 cases of Paecilomyces variotii in the sinonasal tract have been reported in the literature. We present a case of invasive fungal rhinitis secondary to P lilacinus infection in an immunocompromised patient. She was managed successfully with a novel treatment: voriconazole and endonasal microdebridement.
authors.affiliation: ENT and Allergy Associates, 1887 Richmond Ave., Suite 5, Staten Island, NY 10314, USA. shawnciecko@gmail.com
authors.forename: Shawn C
authors.initials: SC
authors.lastname: Ciecko
authors.forename: Richard
authors.initials: R
authors.lastname: Scher
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D016469:Fungemia / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D016040:Lung Transplantation / Q000276:immunology / Q000379:methods; D009181:Mycoses / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D010143:Paecilomyces / Q000302:isolation & purification*; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000601:surgery; D011743:Pyrimidines / Q000627:therapeutic use; D012220:Rhinitis / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole