title: [Effects of several different irritation factors on leukocytes adhesion in microvessels].
abstract: OBJECTIVE
  The interrelation of adhesion between leukocyte and endothelium was studied by several irritation factors.
  
  
  METHODS
  Leukocyte adhesion was observed by impulse electricity irritation, ischemia/reperfusion, endotoxin and IL-8 in venular of rat mesentery.
  
  
  RESULTS
  The results showed these irritation factors resulted in a significant increase in the number of leukocytes adhesion along the venular endothelium of rat mesentery. IL-8 leaded to the most increase of leukocytes adhesion. Especially treated by IL-8 for 30 minutes. The number of leukocytes adhesion of the others was approximately identical.
  
  
  CONCLUSIONS
  The study suggests that impulse electricity irritation, ischemia/reperfusion, endotoxin and IL-8 are able to induce leukocytes and endothelium adhesion, and IL-8 of them has the most effect.
authors.affiliation: Laboratory of Microcirculation, PLA General Hospital, Beijing 100853, China.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Liu
authors.forename: X M
authors.initials: XM
authors.lastname: Zhao
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D004558:Electric Stimulation / Q000009:adverse effects*; D004731:Endotoxins / Q000633:toxicity*; D016209:Interleukin-8 / Q000009:adverse effects*; D007511:Ischemia / Q000378:metabolism; D007962:Leukocytes / Q000166:cytology*; D055806:Microvessels / Q000166:cytology*; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000378:metabolism
chemical_list: D004731:Endotoxins; D016209:Interleukin-8