title: [Effects of coenzyme Q10 supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes].
abstract: OBJECTIVE
  To investigate the effects of CoQlo supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes.
  
  
  METHODS
  Based on a single blinded study design, 18 male adolescent swimming athletes were randomized into two groups, supplement CoQ10 100 mg/d (Q group), or placebo (P group) for 28 days respectively.
  
  
  RESULTS
  (1) After supplementation, the plasma CoQ10 concentration in Q group was significantly elevated and significantly higher compared to P group. (2) After supplementation, the rest plasma MDA level in Q group remained unchanged and was significantly lower compared to P group. (3) The plasma CoQ10 concentration of the 18 athletes was significantly decreased during the first constant endurance exercise. (4) The baseline plasma CoQ10 of the 18 subjects showed significantly positive correlation with VO2max measured in the first incremental exercise. (5) No significant difference of increased level of AKBR between Q group and P group. (6) No significant difference of increase level of VO2max, individual lactate threshold and exercise economy between Q and P group.
  
  
  CONCLUSIONS
  Although there is an increased demand for plasma CoQ10 during endurance exercise and CoQ10 supplement can depress lipid peroxidation, there is no effect of CoQ10 supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes.
authors.affiliation: Shan Dong Institute of Physical Education and Sports, Jinan 250063, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liao
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yue
authors.initials: Y
authors.lastname: Liao
authors.forename: Nian-jun
authors.initials: NJ
authors.lastname: Zheng
authors.forename: Xu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D015444:Exercise; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism / Q000502:physiology*; D010807:Physical Endurance; D013550:Swimming; D014451:Ubiquinone / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D014451:Ubiquinone; C024989:coenzyme Q10