title: Salvage of an infected titanium mesh in a large incisional ventral hernia using medicinal honey and vacuum-assisted closure: a case report and literature review.
abstract: The overall reported percentage of mesh infections is 1.3%. Infections after incisional ventral hernia repair depend on many factors. Salvaging an infected mesh should be the priority, because serious complications are reported following mesh removal. In this case report, a methicillin-resistant Staphylococcus aureus (MRSA)-infected titanium mesh was salvaged by a novel technique, not requiring removal. The combination of vacuum-assisted closure (VAC™ therapy) of the wound and medical honey (L-Mesitran™) proved to be successful in leaving the mesh in situ. We report the successful management of this infected titanium mesh and review the literature regarding the possible pathogenetic mechanisms and treatment options.
authors.affiliation: First Department of Surgery, 424 General Military Hospital, Eukarpias Ave., VST 903, Thessaloniki, Greece. surgchatz@yahoo.gr
authors.forename: G
authors.initials: G
authors.lastname: Chatzoulis
authors.forename: K
authors.initials: K
authors.lastname: Chatzoulis
authors.forename: P
authors.initials: P
authors.lastname: Spyridopoulos
authors.forename: P
authors.initials: P
authors.lastname: Pappas
authors.forename: A
authors.initials: A
authors.lastname: Ploumis
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001672:Biocompatible Materials; D005260:Female; D006555:Hernia, Ventral / Q000601:surgery*; D006722:Honey; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus; D054843:Negative-Pressure Wound Therapy; D009824:Ointments / Q000627:therapeutic use; D019919:Prosthesis Implantation / Q000009:adverse effects; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000382:microbiology / Q000628:therapy*; D013203:Staphylococcal Infections / Q000209:etiology / Q000628:therapy*; D013526:Surgical Mesh / Q000009:adverse effects* / Q000382:microbiology; D014025:Titanium
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D009824:Ointments; D014025:Titanium