title: Proposed pathobiologic mechanisms of hypoxia-ischemia-reperfusion in corticosteroid-resistant neutrophilic asthma and consideration of interleukin 1 targeted therapy.
authors.affiliation: Allergy & Asthma Counsultants PLLC, Bozeman, MT 59718, USA. aw@aacmt.com
authors.forename: Alan A
authors.initials: AA
authors.lastname: Wanderer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000818:Animals; D001249:Asthma / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D002352:Carrier Proteins / Q000502:physiology; D004351:Drug Resistance; D006801:Humans; D000860:Hypoxia / Q000150:complications; D007249:Inflammation / Q000209:etiology; D053583:Interleukin-1beta / Q000037:antagonists & inhibitors / Q000502:physiology*; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D009504:Neutrophils / Q000276:immunology*; D015427:Reperfusion Injury / Q000150:complications* / Q000276:immunology
chemical_list: D000305:Adrenal Cortex Hormones; D002352:Carrier Proteins; D053583:Interleukin-1beta; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human