title: Novelties in treatment approach of poly-neoplasias developed during thyroid pathologies.
abstract: In publication were discussed pathogenic mechanisms which are developed during concordance of malignant tumors of thyroid gland and reproductive systems and dishormonal hyperplasias, also functional disturbances which accompany thyroid gland diseases and principles of treatment during synchronic and metachronic manifestations. The treatment of polyneoplasias by "neurotransmitive control" is proposed. Importance of thyroid suppressive therapy was assessed. The efficacy of thyrotrophic hormone suppression by neurotransmitters in prevention of malignant tumors of reproductive system was reported.
authors.affiliation: Georgian-German Specialized Oncological Clinic, Tbilisi, Georgia.
authors.forename: T
authors.initials: T
authors.lastname: Makaridze
authors.forename: K
authors.initials: K
authors.lastname: Mardaleishvili
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000601:surgery; D004298:Dopamine / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008408:Mastectomy; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy* / Q000378:metabolism; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy* / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D013963:Thyroid Hormones / Q000378:metabolism / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D013965:Thyroidectomy; D013972:Thyrotropin / Q000037:antagonists & inhibitors; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D018687:Antidepressive Agents, Second-Generation; D004298:Dopamine; D009638:Norepinephrine; D012701:Serotonin; D017367:Selective Serotonin Reuptake Inhibitors; D013963:Thyroid Hormones; D013972:Thyrotropin; D013974:Thyroxine