title: Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab.
abstract: A 45-year-old woman was diagnosed with ulcerative colitis and treated with mesalazine, prednisone and, finally, azathioprine and infliximab. Colonoscopy revealed a rectal ulcer, identified by biopsy as a large cell B-lymphoma, positive for leukocyte common antigen (LCA), CD 20 and LMP-1 and negative for CD 3. Three months after withdrawal of all immunosuppressors, a proctocolectomy was performed. The resection specimen contained an area of B-cell polymorphic hyperplasia, but no residual tumour. The patient remains well after 2 years of follow-up, without any further antineoplastic therapy.
authors.affiliation: Gastroenterology, Units, Hospital "Ramón y Cajal", 28034 Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: López San Román
authors.forename: Manuel
authors.initials: M
authors.lastname: Van Domselaar
authors.forename: Miguel
authors.initials: M
authors.lastname: Rivero
authors.forename: Clara
authors.initials: C
authors.lastname: Redondo
authors.forename: Rosario
authors.initials: R
authors.lastname: Arribas
authors.forename: Antonio
authors.initials: A
authors.lastname: Rey