title: Caesarean section for twin pregnancy in a parturient with Brugada syndrome.
abstract: Brugada syndrome is a common cause of sudden cardiac death. We report the anaesthetic management of a woman with Brugada syndrome for elective caesarean section of twins. There are few reports of this disease in pregnancy and we believe this is the first of elective caesarean section in a parturient with the syndrome. The characteristic electrocardiographic changes of the syndrome are linked to sodium channel blockers including local anaesthetics such as bupivacaine. The use of bupivacaine for intrathecal central neuraxial blockade as well as other drugs commonly used in obstetric anaesthesia is discussed.
authors.affiliation: Department of Anaesthesia, St. George's Hospital, London, UK. jbramall@doctors.org.uk
authors.forename: J
authors.initials: J
authors.lastname: Bramall
authors.forename: A
authors.initials: A
authors.lastname: Combeer
authors.forename: J
authors.initials: J
authors.lastname: Springett
authors.forename: R
authors.initials: R
authors.lastname: Wendler
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods*; D053840:Brugada Syndrome / Q000503:physiopathology*; D002045:Bupivacaine / Q000494:pharmacology; D002585:Cesarean Section; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D014427:Twins
chemical_list: D002045:Bupivacaine