title: Schinarisanlactone A, a new bisnortriterpenoid from Schisandra arisanensis.
abstract: A novel triterpenoid, schinarisanlactone A (1), was isolated from the fruits of Schisandra arisanensis. Compound 1 possesses an unprecedented skeleton having a 5/7/7/5/7/5/6/5-fused octacyclic ring system. The structure of 1 was determined by 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. Schinarisanlactone A (1) exhibited significant anti-HIV activity.
authors.affiliation: School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Yu-Chi
authors.initials: YC
authors.lastname: Lin
authors.forename: I-Wen
authors.initials: IW
authors.lastname: Lo
authors.forename: Shun-Ying
authors.initials: SY
authors.lastname: Chen
authors.forename: Pi-Han
authors.initials: PH
authors.lastname: Lin
authors.forename: Ching-Te
authors.initials: CT
authors.lastname: Chien
authors.forename: Sui-yuan
authors.initials: SY
authors.lastname: Chang
authors.forename: Ya-Ching
authors.initials: YC
authors.lastname: Shen
mesh_terms: D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D005638:Fruit / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D032141:Schisandra / Q000737:chemistry*; D013624:Taiwan; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D019380:Anti-HIV Agents; D014315:Triterpenes; C556384:schinarisanlactone A