title: Macrostachyols A-D, new oligostilbenoids from the roots of Gnetum macrostachyum.
abstract: Four new oligostilbenes, macrostachyols A-D (1-4) along with six known stilbenoids (5-10), were isolated from the roots of Gnetum macrostachyum. These compounds were also evaluated for their cytotoxicity towards HeLa and KB cell lines. Only compound 4 showed the significant cytotoxicity to HeLa cells with IC(50) value of 4.13 μM.
authors.affiliation: Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Piyawit
authors.initials: P
authors.lastname: Sri-in
authors.forename: Jirapast
authors.initials: J
authors.lastname: Sichaem
authors.forename: Pongpun
authors.initials: P
authors.lastname: Siripong
authors.forename: Santi
authors.initials: S
authors.lastname: Tip-pyang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D035684:Gnetum / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D018517:Plant Roots; D013267:Stilbenes / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D013267:Stilbenes