title: Titanocene(III)-promoted Barbier-type crotylation of carbonyl compounds.
abstract: A mild, highly regio- and stereoselective method for the crotylation of aldehydes and ketones mediated/catalyzed by titanocene(III) is described. Optimized conditions permit the selective generation of γ-adducts in high yields together with high stereoselectivity, with a predominance of anti stereoisomers.
authors.affiliation: Department of Organic Chemistry, Faculty of Sciences, University of Granada, C. U. Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: Iris
authors.initials: I
authors.lastname: Sancho-Sanz
authors.forename: Delia
authors.initials: D
authors.lastname: Miguel
authors.forename: Alba
authors.initials: A
authors.lastname: Millán
authors.forename: Rosa E
authors.initials: RE
authors.lastname: Estévez
authors.forename: Juan L
authors.initials: JL
authors.lastname: Oller-López
authors.forename: Enrique
authors.initials: E
authors.lastname: Álvarez-Manzaneda
authors.forename: Rafael
authors.initials: R
authors.lastname: Robles
authors.forename: Juan M
authors.initials: JM
authors.lastname: Cuerva
authors.forename: José
authors.initials: J
authors.lastname: Justicia