title: N-{3-[Bis(2-hydroxy-ethyl)amino-meth-yl]-5-nitro-phen-yl}benzamide.
abstract: The title compound, C(18)H(21)N(3)O(5), was prepared by the reaction of 3-benzamido-5-nitro-benzyl methane-sulfonate with diethano-lamine and is an inter-mediate in the synthesis of DNA minor-groove-binding polybenzamide agents capable of being conjugated to additional biologically active species. The asymmetric unit contains two independent mol-ecules, which differ only in the orientations of the hydroxy-ethyl groups. In the crystal structure, inter-molecular N-H⋯O and O-H⋯O hydrogen bonds link mol-ecules into one-dimensional chains.
authors.affiliation: Department of Chemistry, The University of Auckland, Private Bag 92019, Auckland, New Zealand.
authors.forename: Anna
authors.initials: A
authors.lastname: Mai
authors.forename: Gul S
authors.initials: GS
authors.lastname: Khan
authors.forename: George R
authors.initials: GR
authors.lastname: Clark
authors.forename: David
authors.initials: D
authors.lastname: Barker