title: Infliximab aids recovery of anal continence in a patient with perianal Crohn's disease.
abstract: Perianal complications occur in approximately 33% of patients with Crohn's disease, and may be the most prominent or even the presenting complaint suggestive of a diagnosis of Crohn's disease. A case is reported of severe perianal Crohn's disease with anal destruction and incontinence that developed after perianal surgery. Healing of perianal lesions and recovery of anal function was achieved with infliximab therapy.
authors.affiliation: Gastroenterology Service, Centro Hospitalar do Porto-Hospital Geral de Santo António, Porto, Portugal. cidalinacaetano@gmail.com
authors.forename: Cidalina
authors.initials: C
authors.lastname: Caetano
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000503:physiopathology*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003424:Crohn Disease / Q000150:complications* / Q000601:surgery / Q000628:therapy*; D005242:Fecal Incontinence / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D000069285:Infliximab; D008297:Male
chemical_list: D000911:Antibodies, Monoclonal; D000069285:Infliximab