title: N-[3-(tert-Butyl-dimethyl-siloxymeth-yl)-5-nitro-phen-yl]acetamide.
abstract: The title compound, C(15)H(24)N(2)O(4)Si, was prepared by the reaction of (3-acetamido-5-nitro-benz-yl)methanol with tert-butyl-dimethyl-silyl chloride and is a key inter-mediate in the synthesis of novel nonsymmetrical DNA minor groove-binding agents. There are two independent mol-ecules in the structure, which differ primarily in the rotation about the C-O bond next to the Si atom. Two strong N-H⋯O hydrogen bonds align the mol-ecules into a wide ribbon extending approximately parallel to the b axis.
authors.affiliation: Chemistry Department, University of Auckland, Private Bag 92019, Auckland, New Zealand.
authors.forename: Gul S
authors.initials: GS
authors.lastname: Khan
authors.forename: George R
authors.initials: GR
authors.lastname: Clark
authors.forename: David
authors.initials: D
authors.lastname: Barker