title: [The change of malondialdehyde and superoxide dismutase in apoptotic granulosa cell of rat PCO].
abstract: OBJECTIVE
  Rat PCO model was established according to the method of Bogovich. Granulosa cells were collected for apoptotic analysis by Tunel method and for measurement of MDA and SOD.
  
  
  RESULTS
  (1) The percentage of apoptotic granulosa cells of rat PCO was higher than control group (P < 0.001). (2) Higher MDA and lower SOD were detected in granulosa cells of rat PCO.
  
  
  CONCLUSIONS
  The change of MDA and SOD are associated with granulosa cell apoptosis in rat PCO.
authors.affiliation: Department of Physiology, Reproductive Endocrinology Laboratory, Harbin Medical University, Harbin 150086, China.
authors.forename: H
authors.initials: H
authors.lastname: Zhu
authors.forename: J
authors.initials: J
authors.lastname: Ni
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: Q L
authors.initials: QL
authors.lastname: Li
mesh_terms: D000818:Animals; D017209:Apoptosis; D005260:Female; D006107:Granulosa Cells / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism*; D011085:Polycystic Ovary Syndrome / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D008315:Malondialdehyde; D013482:Superoxide Dismutase