title: Pulmonary hypertension confirmed histologically five months prior to scleroderma renal crisis onset.
abstract: A 69-year-old man presented shortness of breath and acute renal failure. He had undergone pulmonary partial resection for lung cancer 5 months prior. On examination, severe hypertension, skin sclerosis of his forearms, and anticentromere antibody were observed. A renal biopsy specimen showed characteristic findings for scleroderma renal crisis, and a right heart catheterization revealed severe pulmonary arterial hypertension. Re-examination of the resected lung specimen revealed sclerodermatous vascular involvement was present.
authors.affiliation: Department of Nephrology, Iwate Prefectural Central Hospital, 1-4-1 Ueda, Morioka, Iwate 020-0060, Japan.
authors.forename: Ryu
authors.initials: R
authors.lastname: Watanabe
authors.forename: Izaya
authors.initials: I
authors.lastname: Nakaya
authors.forename: Mayumi
authors.initials: M
authors.lastname: Yahata
authors.forename: Tohru
authors.initials: T
authors.lastname: Takahashi
authors.forename: Tomomi
authors.initials: T
authors.lastname: Sasajima
authors.forename: Kenichi
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Oura
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sakuma
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Tomichi
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Mori
authors.forename: Jun
authors.initials: J
authors.lastname: Soma
mesh_terms: D058186:Acute Kidney Injury / Q000473:pathology*; D000368:Aged; D001706:Biopsy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000473:pathology*; D007668:Kidney / Q000473:pathology; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000473:pathology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed