title: [Thrombolysis in massive pulmonary embolism based on the volumetric capnography].
abstract: This is the first report of a patient submitted to chemical thrombolysis due to massive pulmonary embolism (PE) during the postoperative period of neurosurgery, in whom due to the lack of adequate clinical conditions, no imaging assessment was performed. Clinical, gasometric and capnographic data allowed the decision to perform the thrombolysis with safety. The P(a-et)CO2 gradient decreased from 46.4 mmHg to 11.8 mmHg (normal < 5 mmHg) and the end-tidal alveolar dead space fraction decreased from 0.85 to 0.37 (normal < 0.15) from the pre-thrombolysis period to the 7th day post-thrombolysis. We conclude that the volumetric capnography (VC) was useful in the patient's diagnosis and clinical follow-up.
authors.affiliation: Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil. marcosmm@fcm.unicamp.br
authors.forename: Marcos Mello
authors.initials: MM
authors.lastname: Moreira
authors.forename: Renato Giuseppe Giovanni
authors.initials: RG
authors.lastname: Terzi
authors.forename: Ilma Aparecida
authors.initials: IA
authors.lastname: Paschoal
authors.forename: Luiz Cláudio
authors.initials: LC
authors.lastname: Martins
authors.forename: Evandro Pinto da Luz
authors.initials: EP
authors.lastname: Oliveira
authors.forename: Antonio Luis Eiras
authors.initials: AL
authors.lastname: Falcão
mesh_terms: D019296:Capnography / Q000379:methods*; D005260:Female; D006801:Humans; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods*; D055815:Young Adult