title: Obesity and prostate cancer: collateral damage in the battle of the bulge.
abstract: Prostate cancer is the most common non-cutaneous malignancy diagnosed in US men. With the increasing prevalence of obesity, it is of interest how this condition impacts prostate cancer. However, only recently has the relationship between obesity and prostate cancer been earnestly studied by investigators. Indeed, the relationship between obesity and prostate cancer appears to be complex one. Therefore, we sought to review the most recent and relevant epidemiological data discussing the link between prostate cancer and obesity. In this review, we will discuss both "biological" and "non-biological" means by which obesity may potentially impact prostate cancer.
authors.affiliation: Division of Urologic Surgery, Department of Surgery and the Duke Prostate Center, Duke University School of Medicine, Durham, NC 27710, USA.
authors.forename: Jean-Alfred
authors.initials: JA
authors.lastname: Thomas
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Freedland
mesh_terms: D015897:Comorbidity; D018450:Disease Progression; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006801:Humans; D008297:Male; D009765:Obesity / Q000453:epidemiology* / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology* / Q000401:mortality; D012307:Risk Factors
chemical_list: D012739:Gonadal Steroid Hormones