title: Application of a functional mathematical index for antibacterial and anticarcinogenic effects of tea catechins.
abstract: Tea leaves produce secondary metabolites that are involved in the defense of the plants against invading pathogens. In the case of green teas, these metabolites are polyphenolic compounds called catechins. Previous studies developed a mathematical formula called functional mathematical index (FMI) that was used to describe the quality of different olive oils and potatoes in terms of compositional parameters and antioxidative properties of individual components. This study extends the development of the FMI concept to define an "optimum tea" based on reported relationships between the content of structurally different catechins of a large number of teas and their dual beneficial effects: antimicrobial activities against a foodborne pathogen and inhibition of human cancer cell lines. The described mathematical approach may be useful for predicting relative beneficial effects of new teas based on their catechin content.
authors.affiliation: Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Rome, Italy. finotti@inran.it
authors.forename: Enrico
authors.initials: E
authors.lastname: Finotti
authors.forename: Enrico
authors.initials: E
authors.lastname: Bersani
authors.forename: Mendel
authors.initials: M
authors.lastname: Friedman
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects; D002392:Catechin / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008433:Mathematics; D013662:Tea / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D016588:Anticarcinogenic Agents; D013662:Tea; D002392:Catechin