title: Stability, marginal bone loss and survival of standard and modified sand-blasted, acid-etched implants in bilateral edentulous spaces: a prospective 15-month evaluation.
abstract: OBJECTIVE
  Chemical modification of the already proven sand-blasted and acid-etched (SLA) implant had increased its surface wettability and consequent early-term osseointegration characteristics. The aim of this clinical trial was to compare the stability changes, success, survival, peri-implant parameters and marginal bone loss (MBL) of the early-loaded standard (SLA) and modified sand-blasted, acid-etched (modSLA) implants.
  
  
  METHODS
  A total of 96 SLA and modSLA implants were placed in a bi-lateral, cross-arch position to the jaws of 22 patients. Resonance frequency analysis (RFA) was used to measure the implant stability in the surgery and following healing after 1, 3 and 6 weeks. At the stage of loading, a panoramic X-ray was obtained and RFA measurement was repeated for all implants. Implants were restored by metal-ceramic crowns and followed for 1 year to determine the success, survival rate, peri-implant parameters and MBL. Results were compared by one- and two-way ANOVA, log-rank test and generalized linear mixed models (P < 0.05).
  
  
  RESULTS
  One modSLA implant was lost after 3 weeks following the surgery yielding to a 100 and 97.91% success rate for SLA and modSLA implants, respectively (P = 0.323). At the loading stage, modSLA implants showed significantly lower MBL (0.18 ± 0.05 mm) than SLA implants (0.22 ± 0.06 mm; P = 0.002). In the loading stage, RFA value of the modSLA implants (60.42 ± 6.82) was significantly higher than the both implant types in the surgical stage (55.46 ± 8.29 and 56.68 ± 8.19), and following 1 (56.08 ± 7.01 and 55.60 ± 9.07) and 3 weeks of healing (55.94 ± 5.95 and 55.40 ± 6.50 for SLA and modSLA implants, respectively).
  
  
  CONCLUSIONS
  modSLA implants demonstrated a better stability and a reduced MBL at the loading stage. Both SLA and modSLA implants demonstrated a favorable success and survival at the end of 15-month follow-up.
authors.affiliation: Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Çapa, Istanbul, Turkey International University for Science and Technology, Damascus, Syria. zcuneyt@hotmail.com
authors.forename: Zihni Cüneyt
authors.initials: ZC
authors.lastname: Karabuda
authors.forename: Jawad
authors.initials: J
authors.lastname: Abdel-Haq
authors.forename: Volkan
authors.initials: V
authors.lastname: Arisan
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods*; D000328:Adult; D016301:Alveolar Bone Loss / Q000209:etiology*; D002484:Cementation / Q000379:methods; D003442:Crowns; D045662:Dental Etching / Q000379:methods*; D015921:Dental Implants; D003774:Dental Plaque Index; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057893:Immediate Dental Implant Loading; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation / Q000601:surgery*; D008297:Male; D016876:Metal Ceramic Alloys / Q000737:chemistry; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000209:etiology; D011446:Prospective Studies; D011862:Radiography, Panoramic; D013499:Surface Properties; D016019:Survival Analysis; D016896:Treatment Outcome; D014732:Vibration; D055815:Young Adult
chemical_list: D015921:Dental Implants; D016876:Metal Ceramic Alloys