title: Experimental and numerical study on the hemodynamics of stenosed carotid bifurcation.
abstract: Numerical simulation is performed to demonstrate that hemodynamic factors are significant determinants for the development of a vascular pathology. Experimental measurements by particle image velocimetry are carried out to validate the credibility of the computational approach. We present a study for determining complex flow structures using the case of an anatomically realistic carotid bifurcation model that is reconstructed from medical imaging. A transparent silicone replica of the artery is developed for in-vitro flow measurement. The dynamic behaviours of blood through the vascular structure based on the numerical and experimental approaches show good agreement.
authors.affiliation: School of Aerospace, Mechanical & Manufacturing Engineering, RMIT University, Bundoora, Australia.
authors.forename: Sherman C P
authors.initials: SC
authors.lastname: Cheung
authors.forename: Kelvin K L
authors.initials: KK
authors.lastname: Wong
authors.forename: Guan Heng
authors.initials: GH
authors.lastname: Yeoh
authors.forename: William
authors.initials: W
authors.lastname: Yang
authors.forename: Jiyuan
authors.initials: J
authors.lastname: Tu
authors.forename: Richard
authors.initials: R
authors.lastname: Beare
authors.forename: Thanh
authors.initials: T
authors.lastname: Phan
mesh_terms: D000328:Adult; D016893:Carotid Stenosis / Q000473:pathology / Q000503:physiopathology*; D003198:Computer Simulation; D018056:Hemorheology / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography; D008297:Male; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D015203:Reproducibility of Results