title: Visualisation and quantification of lung content of radionuclides associated with nuclear and radiological emergencies.
abstract: In a situation when radionuclides accidentally or deliberately are dispersed in the environment, there is a need for rapid investigation of the internal contamination in exposed individuals. In this work, the possibilities of visualising and quantifying uptakes of different radionuclides in the lung region of an adult individual using gamma camera systems have been examined, mainly on a two-headed stationary clinical gamma camera. An anthropomorphic phantom was used to mimic acute lung uptakes in three different body sizes. The gamma camera was calibrated with the lung inserts filled with a homogeneous solution of ⁹⁹Tc(m), ⁴⁶Sc and ³²P, or with point sources of ²⁴¹Am, ⁵⁷Co, ⁸⁵Sr, ¹³⁷Cs and ⁹⁰Sr/⁹⁰Y. It was found that for the stationary gamma camera the minimum detectable activity in the lungs using a 5-min acquisition time ranged from 0.53 kBq for ⁴⁶Sc to 50 kBq for ³²P. Furthermore, the point sources of ¹³⁷Cs, ⁶⁰Co and ⁹⁰Sr/⁹⁰Y (0.16, 0.80 and 2.2 MBq, respectively) located in the lung insert of the phantom, could be clearly visualised, exhibiting distinct intensity maxima. It is thus concluded that gamma camera systems can be useful for rapid assessment of acute intakes of radionuclides associated with emergency preparedness, both in terms of localisation and quantification.
authors.affiliation: Medical Radiation Physics, Department of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, SUS Malmö, SE-20502 Malmö. mats.hansson@med.lu.se
authors.forename: Mats
authors.initials: M
authors.lastname: Hansson
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Rääf
mesh_terms: D000328:Adult; D000398:Air Pollution, Radioactive; D002138:Calibration; D004630:Emergencies; D004784:Environmental Monitoring / Q000379:methods*; D015902:Gamma Cameras; D006801:Humans; D008168:Lung / Q000737:chemistry* / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D011868:Radioisotopes / Q000009:adverse effects* / Q000032:analysis*; D011877:Radionuclide Imaging; D013997:Time Factors
chemical_list: D011868:Radioisotopes