title: [The change of cholesterol level and Na+ -K+ -ATPase activity of erythrocyte membrane in early stage of severe burn patients].
abstract: OBJECTIVE
  To study the relationship between erythrocyte filtration index (EFI) and cholesterol and Na+ -K+ -ATPase activity of erythrocyte membrane in early stage of severe burns.
  
  
  METHODS
  The EFI was measured by means of percolation, the erythrocyte membrane cholesterol level was measured by means of chemically modified electrode, and the membrane Na+ -K+ -ATPase activity by means of detection of Pi.
  
  
  RESULTS
  In early stage of severe burns, the cholesterol level and Na+ -K -ATPase activity of erythrocyte membrane were always higher than those of control group (P < 0.01), but the EFI was lower than that of control group (P < 0.01). The cholesterol level and Na+ -K+ -ATPase activity of the erythrocyte membrane were negative correlation with EFI (r cho= -0.871, r ATPase = -0.801, P < 0.01) nospectively.
  
  
  CONCLUSIONS
  The cholesterol level and Na+ -K+ -ATPase activity of erythrocyte membrane play a key role in the change of EFI.
authors.affiliation: Department of Burns, 2.Laboratoy, Affiliated Hospital of Wannan Medical College, Wuhu 241001, China.
authors.forename: Da-lun
authors.initials: DL
authors.lastname: Lv
authors.forename: Fan
authors.initials: F
authors.lastname: Cui
authors.forename: Xiao-ning
authors.initials: XN
authors.lastname: Li
mesh_terms: D000328:Adult; D002056:Burns / Q000378:metabolism*; D016022:Case-Control Studies; D002784:Cholesterol / Q000737:chemistry*; D004910:Erythrocyte Membrane / Q000737:chemistry*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
chemical_list: D002784:Cholesterol; D000254:Sodium-Potassium-Exchanging ATPase