title: Psychometric properties of the Children's Depression Rating Scale-Revised in adolescents.
abstract: OBJECTIVE
  The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group.
  
  
  METHODS
  Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after 12 weeks of fluoxetine treatment. Global improvement was also assessed at week 12 (or exit). Reliability and validity were analyzed using Classical Test Theory (item-total correlations and internal consistency) and correlations between the CDRS-R and other outcomes.
  
  
  RESULTS
  Adolescents (n = 145) were evaluated at screening; 113 (77.9%) met criteria for major depressive disorder, 8 (5.5%) had subthreshold depressive symptoms, and 24 (16.6%) had minimal depressive symptoms. Ninety-four adolescents had a baseline visit after 1 week, and 88 were treated with fluoxetine. Internal consistency for the CDRS-R was good at all three visits (screening: 0.79; baseline: 0.74; exit: 0.92), and total score was highly correlated with global severity (r = 0.87, 0.80, and 0.93; p < 0.01). Only exit CDRS-R score was significantly correlated with global functioning (Children's Global Assessment Scale; r = -0.77; p < 0.01). Reductions on the CDRS-R total score were highly correlated with improvement scores at exit (Clinical Global Impressions-Improvement; r = -0.83; p < 0.01).
  
  
  CONCLUSIONS
  The results demonstrate good reliability and validity in adolescents with depression.
authors.affiliation: Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8589, USA. taryn.mayes@utsouthwestern.edu
authors.forename: Taryn L
authors.initials: TL
authors.lastname: Mayes
authors.forename: Ira H
authors.initials: IH
authors.lastname: Bernstein
authors.forename: Charlotte L
authors.initials: CL
authors.lastname: Haley
authors.forename: Betsy D
authors.initials: BD
authors.lastname: Kennard
authors.forename: Graham J
authors.initials: GJ
authors.lastname: Emslie
mesh_terms: D000293:Adolescent; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D015203:Reproducibility of Results; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012720:Severity of Illness Index
chemical_list: D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors