title: Probability of survival based on etiology of cardiopulmonary arrest in pediatric patients.
abstract: OBJECTIVE
  To aggregate data across institutions to identify, characterize, and differentiate potential survivors from nonsurvivors based on etiology of event.
  
  
  OBJECTIVE
  To evaluate the association of the cardiopulmonary resuscitation (CPR) duration and probability of survival (Ps), stratified by etiology of arrest.
  
  
  BACKGROUND
  In-hospital cardiac arrests occur in 2-6% of pediatric patients with poor survival rates resulting in significant expenditures of time and resources.
  
  
  METHODS
  Retrospective data from six pediatric hospitals on patients suffering from pulseless cardiac arrests receiving CPR for over one minute were analyzed. Data included demographics, reason for code, precardiac arrest diagnosis, devices and treatment, management strategies during cardiac arrest, compression duration, outcome at hospital discharge, and neurologic outcome of survivors at hospital discharge. Results of logistic regression analysis generated predicated probabilities of survival for duration of compression. Patients were stratified by cardiac-induced cardiac arrests (CICA) and respiratory-induced cardiac arrest (RICA).
  
  
  RESULTS
  A total of 257 patients were included, and 27% of CICA and 35% of RICA patients survived to hospital discharge. Ps was initially lower for the CICA patients (Ps at 1 min = 29%) and remained constant (Ps at 60 min = 25%). RICA patients'Ps was higher initially (Ps at 1 min = 62%) but demonstrated a dramatic drop within the first 60 min of CPR (Ps at 60 min = 0.2%).
  
  
  CONCLUSIONS
  Probability of survival curves based on duration of CPR was statistically significantly different for CICA patients compared to RICA patients.
authors.affiliation: Medical College of Wisconsin, Milwaukee WI, USA. RBerens@chw.org
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Berens
authors.forename: Laura D
authors.initials: LD
authors.lastname: Cassidy
authors.forename: Jennifer
authors.initials: J
authors.lastname: Matchey
authors.forename: Deborah
authors.initials: D
authors.lastname: Campbell
authors.forename: Krista D
authors.initials: KD
authors.lastname: Colpaert
authors.forename: Tangela
authors.initials: T
authors.lastname: Welch
authors.forename: Michelle
authors.initials: M
authors.lastname: Lawson
authors.forename: Cheryl
authors.initials: C
authors.lastname: Peterson
authors.forename: Justine
authors.initials: J
authors.lastname: O'Flynn
authors.forename: Mary
authors.initials: M
authors.lastname: Dearth
authors.forename: Kelly S
authors.initials: KS
authors.lastname: Tieves
mesh_terms: D000293:Adolescent; D016887:Cardiopulmonary Resuscitation; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology; D003422:Critical Care / Q000706:statistics & numerical data; D005260:Female; D006323:Heart Arrest / Q000150:complications / Q000209:etiology* / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007431:Intraoperative Complications / Q000209:etiology / Q000401:mortality; D016015:Logistic Models; D008297:Male; D009422:Nervous System Diseases / Q000453:epidemiology / Q000209:etiology; D011336:Probability; D012143:Respiratory Physiological Phenomena; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D055815:Young Adult