title: [Regulatory network of hippocampal-systemic arterial blood pressure during epileptic network reestablishment].
abstract: OBJECTIVE
  To investigate the regulatory network of hippocampal-systemic arterial blood pressure during epileptic network reestablishment.
  
  
  METHODS
  7.2 microg picrotoxin (PTX) was microinjected into the right HPC (RHPC) to induce rat epilepsy. Contralateral hippocampal EEG, single unit discharges, femoral artery blood pressure and ECG were recorded simultaneously.
  
  
  RESULTS
  PTX might induce: (1) A resemblance interspike intervals (ISI) spot distribution of long duration neuronal burst and unit after discharges in contralateral HPC. (2) Delayed the initiation time of hippocampal neuronal bursts coupled with arterial blood pressure depression. (3) Hippocampal neuronal burst or unit after discharges coupled complexly with arterial blood pressure depression. (4) Resemblance hippocampal EEG interpeak intervals (IPI) and neuronal firing ISI spot distribution coupled with arterial blood pressure depression.
  
  
  CONCLUSIONS
  During contralateral hippocampal epileptic network reestablishment after microinjection of PTX to the RHPC, the function of the hippocampal-arterial blood pressure regulatory network could be modulated by characteristic network and neuronal temporal code patterning.
authors.affiliation: Department of Physiology, School of Medicine, Wuhan University, Wuhan 430071, China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Zhou
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.forename: Xiao-Fei
authors.initials: XF
authors.lastname: Wei
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.forename: Jun-Fang
authors.initials: JF
authors.lastname: Wu
authors.forename: Zu-Yu
authors.initials: ZY
authors.lastname: Zou
authors.forename: Yong-Jian
authors.initials: YJ
authors.lastname: Qi
authors.forename: Dan
authors.initials: D
authors.lastname: Han
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D004562:Electrocardiography; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D006624:Hippocampus / Q000502:physiology* / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley