title: Synthesis of Novel Functionalized 4-Aza-2,3-Didehydropodophyllotoxin Derivatives with Potential Antitumor Activity.
abstract: Novel arylamino alcohols were synthesized and these alcohols were used to prepare 12 novel N-(2-hydroxy-ethyl)-2,3-didehydroazapodophyllotoxins, in one step, by simple reflux in ethanol. Isolated yields in the range of 50-70% were obtained.
authors.affiliation: Department of Chemistry, University of Puerto Rico, Humacao, Puerto Rico.
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar
authors.forename: Antonio E
authors.initials: AE
authors.lastname: Alegria