title: Amphiphilic amylose-g-poly(meth)acrylate copolymers through "click" onto grafting method.
abstract: Periodate oxidation and subsequent reductive amination with propargylamine was adopted for the controlled functionalization of amylose with alkyne groups, whereas ATRP polymerization was exploited to obtain end-(α)- or end-(ω)-azide functionalized poly(meth)acrylates to be used as "click" reagents in Cu(I) catalyzed azide-alkyne [3 + 2] dipolar cycloaddition. Amylose was effectively grafted with poly(n-butyl acrylate), poly(n-butyl methacrylate), poly(n-hexyl methacrylate), and poly(dimethylaminoethyl methacrylate) with this strategy. Their structure and composition were confirmed by FT-IR, NMR spectroscopies, and thermogravimetric analysis (TGA). Dynamic and static light scattering analyses, as well as TEM microscopy showed that the most amphiphilic among these hybrid graft copolymers self-assembled in water, yielding nanoparticles with ca. 30 nm diameter.
authors.affiliation: Istituto per i Processi Chimico-Fisici, Consiglio Nazionale delle Ricerche (IPCF-CNR), Area della Ricerca, Pisa, Italy. monica.bertoldo@ipcf.cnr.it
authors.forename: Monica
authors.initials: M
authors.lastname: Bertoldo
authors.forename: Giovanni
authors.initials: G
authors.lastname: Zampano
authors.forename: Federico
authors.initials: F
authors.lastname: La Terra
authors.forename: Valentina
authors.initials: V
authors.lastname: Villari
authors.forename: Valter
authors.initials: V
authors.lastname: Castelvetro
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D000688:Amylose / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry*; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry; D009757:Nylons; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D011109:Polymethacrylic Acids / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000179:Acrylates; D008689:Methacrylates; D009757:Nylons; D011108:Polymers; D011109:Polymethacrylic Acids; C407037:poly(2-(dimethylamino)ethyl methacrylate); C498324:poly(n-butyl acrylate); C068872:polybutyl methacrylate; D000688:Amylose