title: 2-(4-Methyl-2-phenyl-piperazin-4-ium-1-yl)pyridine-3-carboxyl-ate dihydrate.
abstract: The title compound, C(17)H(19)N(3)O(2)·2H(2)O, is particularly useful in the preparation of mirtaza-pine, which is the active agent in a new class of anti-depressants. It crystallized as a zwitterion with two mol-ecules of water in the asymmetric unit. The crystal structure is dominated by a system of hydrogen bonds involving the positively charged N atom and both water mol-ecules.
authors.forename: Ai-Jun
authors.initials: AJ
authors.lastname: Li
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Zhang
authors.forename: Wen-Qian
authors.initials: WQ
authors.lastname: Sun
authors.forename: Xue-Qin
authors.initials: XQ
authors.lastname: Zhou
authors.forename: Dong-Zhi
authors.initials: DZ
authors.lastname: Liu