title: Factor XIII deficiency: report of two cases.
abstract: Factor XIII deficiency is one of the rare clotting factor deficiencies. Although rare, it is an important disorder because of seriousness of its bleeding manifestations, in particular the incidence of intracranial hemorrhage is higher than any other bleeding disorder Hence an early diagnosis is extremely important where bleeding manifestations can be prevented by prophylactic factor XIII replacement given at every 4-6 week interval. Case1 presents the management of a factor deficiency associated with a very rare blood group AB+ve, while the case 2 reports the successful surgical management with a replacement therapy
authors.affiliation: Department of Pedodontics and Preventive Dentistry, College of Dental Sciences, Davangere, Karnataka, India.
authors.forename: P
authors.initials: P
authors.lastname: Poornima
authors.forename: K K
authors.initials: KK
authors.lastname: Shashibhushan
authors.forename: K P
authors.initials: KP
authors.lastname: Bharath
authors.forename: V V
authors.initials: VV
authors.lastname: Subba Reddy
mesh_terms: D000293:Adolescent; D002648:Child; D003029:Coagulants / Q000627:therapeutic use; D003731:Dental Caries / Q000628:therapy; D003937:Diagnosis, Differential; D005176:Factor XIII / Q000627:therapeutic use; D005177:Factor XIII Deficiency / Q000175:diagnosis*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008297:Male; D006472:Oral Hemorrhage / Q000517:prevention & control; D010482:Periapical Abscess / Q000628:therapy; D012390:Root Canal Therapy; D014081:Tooth Extraction
chemical_list: D003029:Coagulants; D006490:Hemostatics; D005176:Factor XIII