title: Clear-cell renal carcinoma metastasis to the base of the tongue and sphenoid sinus: Two very rare atypical ENT locations.
abstract: BACKGROUND
  Kidney cancer, and especially clear cell carcinoma, has an unpredictable clinical course, with metastatic potential that is variable over time and in location. Six percent of atypical locations are ENT. The three most frequent sites are the thyroid, sinus and parotid gland.
  
  
  METHODS
  We report two rare locations: the base of the tongue, and the sphenoid sinus.
  
  
  CONCLUSIONS
  First-line treatment is surgical, due to low radiosensitivity, with radiation therapy as a possible second line. Functional impact is a prime issue, to avoid functional mutilation.
  
  
  CONCLUSIONS
  Such metastases may sometimes occur years after the discovery of the primitive renal tumor; any history of kidney cancer should, therefore, be noted in patients with suspect ENT lesions.
authors.affiliation: Service d'oto-rhino-laryngologie et chirurgie cervicofaciale, hôpital d'instruction des armées Sainte-Anne de Toulon, BP 600, 83800 Toulon-Naval, France. jbmorvan@hotmail.com
authors.forename: J-B
authors.initials: JB
authors.lastname: Morvan
authors.forename: J-B
authors.initials: JB
authors.lastname: Veyrières
authors.forename: O
authors.initials: O
authors.lastname: Mimouni
authors.forename: O
authors.initials: O
authors.lastname: Cathelinaud
authors.forename: L
authors.initials: L
authors.lastname: Allali
authors.forename: P
authors.initials: P
authors.lastname: Verdalle
mesh_terms: D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D007828:Laryngoscopy; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D049268:Positron-Emission Tomography; D018714:Radiotherapy, Adjuvant; D013101:Sphenoid Sinus / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014062:Tongue Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery