title: Hepatocellular carcinoma, with portal thrombus after viral eradication, disappeared by 5-fluorouracil and interferon.
abstract: Hepatocarcinogenesis after a sustained virological response (SVR) in type C chronic hepatitis and cirrhosis is an important issue in endemic areas; hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) therapy is especially very hard. We herein report a first case in which combination therapy with interferon-α and continuous intra-arterial infusion of 5-fluorouracil (designated as FAIT) provided a complete response in HCC with PVTT after SVR. Therefore, we think that FAIT is a good option to treat HCC with or without PVTT, even after SVR.
authors.affiliation: Tomofumi Miura, Nobuaki Suzuki, Junichiro Nakamura, Satoshi Yamada, Tsutomu Miura, Masahiko Yanagi, Toru Takahashi, Division of Gastroenterology and Hepatology, Nagaoka Red Cross Hospital, 2-297-1, Senshu, Nagaoka, Niigata 940-2085, Japan.
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Miura
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Suzuki
authors.forename: Junichiro
authors.initials: J
authors.lastname: Nakamura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamada
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Miura
authors.forename: Masahiko
authors.initials: M
authors.lastname: Yanagi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Usuda
authors.forename: Iwao
authors.initials: I
authors.lastname: Emura
authors.forename: Toru
authors.initials: T
authors.lastname: Takahashi