title: Dynamic kinetic resolution of azlactones catalyzed by chiral Brønsted acids.
abstract: Chiral Brønsted acids have been shown for the first time to catalyze the dynamic kinetic resolution of azlactones. 3,3'-Bis-(9-anthryl)-BINOL phosphoric acid 3c is particularly effective in the case of 4-aryl-substituted substrates, producing 85-92% ee's.
authors.affiliation: Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.
authors.forename: Guojian
authors.initials: G
authors.lastname: Lu
authors.forename: Vladimir B
authors.initials: VB
authors.lastname: Birman