title: An international quality of life instrument to assess wellbeing in adults who are HIV-positive: a short form of the WHOQOL-HIV (31 items).
abstract: Few cross-cultural measures are available to assess quality of life (QoL) in HIV/AIDS. A short form of the WHOQOL-HIV-the WHOQOL-HIV BREF-was developed and tested. Survey data from 1,923 HIV-positive adults (selected for age, gender and disease stage) were collected in 8 culturally diverse centres. The 'best' HIV-specific item was extracted from five HIV facets of the WHOQOL-HIV long form using information about item correlations with QoL, health and domains, item discriminant validity and centre problems. The five identified items were then integrated with the WHOQOL-BREF to complete the 31 item WHOQOL-HIV BREF. This short form shows good internal consistency reliability and discriminant validity for 'known' disease stages. Confirmatory Factor Analysis showed an overall good fit for a six domains model (Comparative Fit Index = 0.97), supporting scoring. Quality of life in different cultures is reported. A value of the WHOQOL-HIV short form is in monitoring QoL in multi-national clinical trials, and in clinical practice.
authors.affiliation: Research & Metrics, Population Services International, Washington, DC, USA.
authors.forename: Kathryn Ann
authors.initials: KA
authors.lastname: O'Connell
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Skevington
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003431:Cross-Cultural Comparison; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014944:World Health Organization