title: Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib.
authors.forename: Wendy
authors.initials: W
authors.lastname: Deenik
authors.forename: Bronno
authors.initials: B
authors.lastname: van der Holt
authors.forename: Jeroen J W M
authors.initials: JJ
authors.lastname: Janssen
authors.forename: Isabel W T
authors.initials: IW
authors.lastname: Chu
authors.forename: Peter J M
authors.initials: PJ
authors.lastname: Valk
authors.forename: Gert J
authors.initials: GJ
authors.lastname: Ossenkoppele
authors.forename: Ilse P
authors.initials: IP
authors.lastname: van der Heiden
authors.forename: Pieter
authors.initials: P
authors.lastname: Sonneveld
authors.forename: Ron H N
authors.initials: RH
authors.lastname: van Schaik
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Cornelissen
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001549:Benzamides; D004305:Dose-Response Relationship, Drug; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics*; D010879:Piperazines / Q000008:administration & dosage*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011379:Prognosis; D011743:Pyrimidines / Q000008:administration & dosage*
chemical_list: C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate