title: Two-year natural course of anterior disc displacement with reduction.
abstract: OBJECTIVE
  To test if the disappearance of clicking associated with anterior disc displacement with reduction (ADDR) is related to a gradual loss of reducing capacity of the disc in the temporomandibular joint.
  
  
  METHODS
  Twenty-five ADDR subjects without and 30 ADDR subjects with intermittent locking participated in this 2-year follow-up study. Clinical examinations and mandibular movement recordings were performed at baseline and after 1 and 2 years. If mandibular movement recordings no longer showed signs of an ADDR, magnetic resonance imaging (MRI) of the disc was carried out.
  
  
  RESULTS
  Mandibular movement recordings showed the moment of disc reduction (MDR) to be stable over the observation period in the subjects without intermittent locking (P = .95). In the subjects with intermittent locking, MDR had shifted to a later mouth opening (P = .000). In seven of these subjects, clicking had totally disappeared, usually without symptoms of permanent locking. On the MRI scans of these subjects, the disc displacement was still present, but with no, or only a partial, reduction.
  
  
  CONCLUSIONS
  Intermittent locking may be indicative of the development of a disc displacement without reduction. This loss is only rarely accompanied by symptoms of permanent locking.
authors.affiliation: Department of Oral Kinesiology, Academic Centre for Dentistry, Amsterdam (ACTA), Amsterdam, The Netherlands.
authors.forename: Stanimira
authors.initials: S
authors.lastname: Kalaykova
authors.forename: Frank
authors.initials: F
authors.lastname: Lobbezoo
authors.forename: Machiel
authors.initials: M
authors.lastname: Naeije
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001314:Auscultation / Q000379:methods; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D004204:Joint Dislocations / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008334:Mandible / Q000503:physiopathology; D008875:Middle Aged; D009068:Movement; D013016:Sound; D019224:Temporomandibular Joint Disc / Q000473:pathology* / Q000503:physiopathology; D013705:Temporomandibular Joint Disorders / Q000503:physiopathology*; D055815:Young Adult