title: Non-contrast computed tomography is comparable to contrast-enhanced computed tomography for aortic volume analysis after endovascular abdominal aortic aneurysm repair.
abstract: OBJECTIVE
  To evaluate whether non-contrast computed tomography (NCCT) images are as reliable as contrast-enhanced computed tomography (CECT) images for the measurement of aortic volume (AV).
  
  
  METHODS
  A total of 316 pairs of AVs were retrospectively measured from 316 consecutive patients, who underwent endovascular aneurysm repair (EVAR). A standardised multidetector computed tomography protocol was used to obtain precontrast, arterial and delay-phase images. A single blinded, experienced observer measured the AV from the lowest renal artery to the aortic bifurcation by means of the disc-summation method, using the precontrast and arterial-phase images. A second blinded observer measured the AV again in 16 randomly chosen cases.
  
  
  RESULTS
  Both NCCT and CECT yielded similar AVs that were highly correlated (r(2) = 0.99; P < 0.0001). Bland and Altman analysis revealed a small bias (mean ± 2 standard deviations: -0.9 ± 8 ml). The intraclass correlation coefficients (all >0.99; P < 0.0001) and low repeatability coefficients indicated that the AVs were reproducible with both methods.
  
  
  CONCLUSIONS
  The AVs measured from NCCT images were accurate and highly reproducible compared with those from CECT images. Therefore, NCCT can be a reasonable alternative to CECT for AV assessment after EVAR. This is particularly important for patients with renal insufficiency (potentially sparing them from nephrotoxic contrast agents and unnecessary radiation) or allergy to contrast agents.
authors.affiliation: Department of Radiology, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, TX 77030, USA.
authors.forename: P
authors.initials: P
authors.lastname: Nambi
authors.forename: R
authors.initials: R
authors.lastname: Sengupta
authors.forename: Z
authors.initials: Z
authors.lastname: Krajcer
authors.forename: R
authors.initials: R
authors.lastname: Muthupillai
authors.forename: N
authors.initials: N
authors.lastname: Strickman
authors.forename: B Y C
authors.initials: BY
authors.lastname: Cheong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D001027:Aortography / Q000379:methods*; D019917:Blood Vessel Prosthesis Implantation; D003287:Contrast Media / Q000009:adverse effects; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D008297:Male; D015588:Observer Variation; D011237:Predictive Value of Tests; D012042:Registries; D051437:Renal Insufficiency / Q000150:complications; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013781:Texas; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media