title: Diagnostic dilemma of JMML coexisting with CMV infection.
abstract: Juvenile myelomonocytic leukemia (JMML) is a rare mixed myeloproliferative and myelodysplastic disorder of early childhood, characterized by excessive proliferation of monocytic and granulocytic cells, along with myelodysplastic features. There are reports of viral infections mimicking JMML, with all clinical and hematological parameters normalizing on resolution of infection. The authors describe a 1- year- old boy with concomitant JMML and CMV infection. The diagnostic dilemma, the significance of distinguishing it from a mimicking viral infection, as well as potential synergistic effect of concomitant infections on the presentation or actual disease severity of underlying JMML will be discussed.
authors.affiliation: Department of Pediatrics, AIIMS, New Delhi, India.
authors.forename: Kriti
authors.initials: K
authors.lastname: Puri
authors.forename: Prashant
authors.initials: P
authors.lastname: Singh
authors.forename: Rashmi Ranjan
authors.initials: RR
authors.lastname: Das
authors.forename: Rachna
authors.initials: R
authors.lastname: Seth
authors.forename: Ritu
authors.initials: R
authors.lastname: Gupta
mesh_terms: D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D054429:Leukemia, Myelomonocytic, Juvenile / Q000150:complications*; D008297:Male; D019562:Viral Load
chemical_list: D007075:Immunoglobulin M