title: [Renal and spleen infarction after massive consumption of cannabis and cocaine in a young man].
abstract: Cannabis is the most widely consumed drug in the world, particularly among young subjects. Cocaine is the third leading illicit drug. Cases of renal infarction associated with combined consumption of cannabis and cocaine have been reported in the literature. We describe the case of a 24-year-old man who presented renal and spleen infarction after massive consumption of cannabis and cocaine. Both vascular events arose on healthy arteries. Etiological tests were negative leading to the conclusion that the events resulted from a toxic cause related to cannabis and cocaine consumption. Different mechanisms, potentially including thrombosis, might explain the association of cannabis and cocaine with vascular events. We suggest that a systematic search for cannabis and cocaine consumption among young victims of vascular disease might be useful.
authors.affiliation: Unité d'écho-doppler et de médecine vasculaire, CHU La Cavale-Blanche, boulevard Tanguy-Prigent, Brest cedex, France.
authors.forename: P-Y
authors.initials: PY
authors.lastname: Le Guen
authors.forename: S
authors.initials: S
authors.lastname: Gestin
authors.forename: E
authors.initials: E
authors.lastname: Plat
authors.forename: P
authors.initials: P
authors.lastname: Quéhé
authors.forename: L
authors.initials: L
authors.lastname: Bressollette
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002188:Cannabis / Q000506:poisoning*; D003042:Cocaine / Q000506:poisoning*; D006801:Humans; D007238:Infarction / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D007668:Kidney / Q000098:blood supply*; D008297:Male; D013159:Splenic Infarction / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D000925:Anticoagulants; D003042:Cocaine