title: Multiple functions of the vesicular proton pump in nerve terminals.
abstract: Synaptic vesicles are acidified by a proton pump (vATPase), which allows vesicular uptake of neurotransmitters. After vesicle exocytosis, continued operation of the vATPase would seem to serve no useful function. In this issue of Neuron, however, Zhang and colleagues show that continued pumping alkalinizes the cytoplasm, accelerating endocytosis.
authors.affiliation: Department of Medical Physiology and Biophysics, University of Seville, 41009 Seville, Spain.
authors.forename: Lucia
authors.initials: L
authors.lastname: Tabares
authors.forename: Bill
authors.initials: B
authors.lastname: Betz