title: [Distribution of HCV genotypes in volunteer blood donors in Guangzhou].
abstract: OBJECTIVE
  To determine the distribution of HCV genotypes among volunteer blood donors in Guangzhou.
  
  
  METHODS
  Six-nine HCV RNA-positive samples were collected from volunteer blood donors in Guangzhou. NS5B fragments of HCV were amplified followed by DNA sequencing and phylogenetic analysis.
  
  
  RESULTS
  HCV genotypes were determined for 67 samples. Among them, the subtypes 1b, 2a, 3a, 3b, 6a and 6n were detected at the frequencies of 37.31%, 4.48%, 7.46%, 4.48%, 44.78% and 1.49%, respectively.
  
  
  CONCLUSIONS
  HCV 1b and 6a are the most predominant two subtypes among volunteer blood donors in Guangzhou.
authors.affiliation: Department of Blood Transfusion, People's Hospital of Guangdong Province, Guangzhou, China. yehanshen2009@126.com
authors.forename: Han-shen
authors.initials: HS
authors.lastname: Ye
authors.forename: Ru
authors.initials: R
authors.lastname: Xu
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Xia
authors.initials: X
authors.lastname: Rong
authors.forename: Wen-feng
authors.initials: WF
authors.lastname: Hua
authors.forename: Xin
authors.initials: X
authors.lastname: Ye
authors.forename: Guang-ping
authors.initials: GP
authors.lastname: Ruo
authors.forename: Yong-shui
authors.initials: YS
authors.lastname: Fu
mesh_terms: D001782:Blood Donors; D002681:China; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral