title: [Effect of acute exhaustive exercise on gastrointestinal transit rate and nitrergic nerves in myenteric plexus in rats ileum].
abstract: OBJECTIVE
  To investigate the effect of acute exhaustive exercise on gastrointestinal motility and its enteric nervous mechanisms.
  
  
  METHODS
  24 rats were randomly divided into control group (C) and acute exhaustive exercise group (AEE). The rate of gastrointestinal transit was measured and histologic changes of nitriergic nerves in ileum myenteric plexus were observed with enzymatic histochemical and image analytic technique.
  
  
  RESULTS
  In the rats of AEE group, the rate of gastrointestinal transit was delayed comparing with C group (P < 0.05), the numbers of nitrergic neurons and expression levels of nitric oxide synthase (NOS) in the ileum myenteric plexus significantly increased comparing with C group (P < 0.01).
  
  
  CONCLUSIONS
  It is possible that increase of nitrergic neurons and expression levels of NOS in the myenteric plexus of small intestine are one of the mechanisms of delay of gastrointestinal transit rate in acute exhaustive exercise rats.
authors.affiliation: Department of Histology and Embryology, Wenzhou Medical College, Wenzhou 325035, China.
authors.forename: Ya-ning
authors.initials: YN
authors.lastname: Lei
authors.forename: You-mei
authors.initials: YM
authors.lastname: Ding
mesh_terms: D000818:Animals; D005769:Gastrointestinal Motility / Q000502:physiology*; D005772:Gastrointestinal Transit / Q000502:physiology*; D007082:Ileum / Q000294:innervation*; D008297:Male; D009043:Motor Activity; D009197:Myenteric Plexus / Q000378:metabolism; D026602:Nitrergic Neurons / Q000166:cytology*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D019001:Nitric Oxide Synthase