title: Treatment of acute pediatric pain.
abstract: Pediatric neurologists frequently treat acute pain in children. A broad range of medication options is available including nonsteroidal anti-inflammatory drugs, opioids, and other analgesic adjuvants, such as antidepressants and antiepileptics. This article reviews the physiology underlying the experience of pain and compares the pharmacologic mechanisms and properties of these medications, providing a framework for developing effective multimodal medical treatment approaches to pain in children.
authors.affiliation: Department of Anesthesiology and Critical Care, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA. KRAEMER@email.chop.edu
authors.forename: F Wickham
authors.initials: FW
authors.lastname: Kraemer
mesh_terms: D000277:Adjuvants, Pharmaceutic / Q000627:therapeutic use; D000367:Age Factors; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods; D000529:Complementary Therapies / Q000379:methods; D006801:Humans; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy*; D059408:Pain Management; D010147:Pain Measurement / Q000379:methods; D011613:Psychotherapy / Q000379:methods
chemical_list: D000277:Adjuvants, Pharmaceutic; D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal