title: Becker myotonia congenita associated with Wolff-Parkinson-White syndrome.
abstract: Becker's disease is a congenital myotonia with an autosomal recessive pattern of inheritance. Unlike myotonic dystrophy, it is not associated with cardiopathy. We present a 32-year-old man with Becker's disease diagnosed at age 11. He suffered episodes of loss of consciousness preceded by palpitations when he performed strenuous physical exercise. The electrocardiogram reveals a Wolff-Parkinson-White syndrome. Review of the literature in MEDLINE using the search terms of congenital myotonia or Becker's disease and arrhythmia or heart disease only found 2 articles on Thomsen disease but none on Becker's disease. Becker's myotonia congenita may exceptionally be associated with cardiopathy, thus patients with this disorder should have a cardiac evaluation.
authors.affiliation: Department of Neurology, Virgen de la Salud Hospital, Toledo, Spain.
authors.forename: Pedro Enrique Jiménez
authors.initials: PE
authors.lastname: Caballero
mesh_terms: D000328:Adult; D018118:Chloride Channels / Q000235:genetics; D004562:Electrocardiography; D006801:Humans; D008297:Male; D009224:Myotonia Congenita / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications* / Q000235:genetics / Q000503:physiopathology
chemical_list: C086321:CLC-1 channel; D018118:Chloride Channels