title: Converting poorly soluble materials into stable aqueous nanocolloids.
abstract: Aqueous nanocolloids of poorly soluble materials were produced via sonicated layer-by-layer (LbL) encapsulation with polycation / polyanion shells. Synergy of simultaneous breaking powder particles with ultrasonication and coating them with polycations allowed for the production of 150-200 nm diameter polyelectrolyte coated nanoparticles with sufficient surface electrical potential for colloidal stability. This technique increases water dispersibility of low soluble materials ranging from anticancer drugs to anticorrosion agents, dyes and inorganic salts.
authors.affiliation: Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisianna, United States.
authors.forename: Yuri M
authors.initials: YM
authors.lastname: Lvov
authors.forename: Pravin
authors.initials: P
authors.lastname: Pattekari
authors.forename: Xingcai
authors.initials: X
authors.lastname: Zhang
authors.forename: Vladimir
authors.initials: V
authors.lastname: Torchilin
mesh_terms: D003102:Colloids / Q000737:chemistry*; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry; D000071228:Polyelectrolytes; D012995:Solubility
chemical_list: D003102:Colloids; D011073:Polyamines; D000071228:Polyelectrolytes