title: Marked improvement of heart failure upon adequate titration of continuous positive airway pressure in a patient with obstructive sleep apnea.
abstract: Sleep disordered breathing (SDB) is frequently present in heart failure (HF), and it may take the form of obstructive (OSA) and central (CSA) sleep apnea. The use of continuous positive airway pressure (CPAP) in patients with OSA and HF is associated with an improved neuroendocrine profile and cardiac function. The degree of upper airway obstruction and the airway closing pressure (and the PAP pressure used to relieve it) may all be highly variable in a setting of uncontrolled HF, mostly due to variable airway oedema. We present a case of a man with HF whose cardiac symptoms radically improved after adequate treatment of his OSA with an auto-adjusting PAP device.
authors.affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USA.
authors.forename: Deena
authors.initials: D
authors.lastname: Raval
authors.forename: Lawrence P
authors.initials: LP
authors.lastname: Bernstein
authors.forename: Randall E
authors.initials: RE
authors.lastname: Williams
authors.forename: Tomasz J
authors.initials: TJ
authors.lastname: Kuzniar
mesh_terms: D000368:Aged; D045422:Continuous Positive Airway Pressure; D006333:Heart Failure / Q000150:complications* / Q000517:prevention & control*; D006801:Humans; D008297:Male; D011175:Positive-Pressure Respiration; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000628:therapy*