title: Noninvasive assessment of burn wound severity using optical technology: a review of current and future modalities.
abstract: Clinical examination alone is not always sufficient to determine which burn wounds will heal spontaneously and which will require surgical intervention for optimal outcome. We present a review of optical modalities currently in clinical use and under development to assist burn surgeons in assessing burn wound severity, including conventional histology/light microscopy, laser Doppler imaging, indocyanine green videoangiography, near-infrared spectroscopy and spectral imaging, in vivo capillary microscopy, orthogonal polarization spectral imaging, reflectance-mode confocal microscopy, laser speckle imaging, spatial frequency domain imaging, photoacoustic microscopy, and polarization-sensitive optical coherence tomography.
authors.affiliation: Department of Surgery, Division of Trauma, Burns, Critical Care and Acute Care Surgery, University of California, Irvine, Orange, CA 92806, USA. mkaiser@uci.edu
authors.forename: Meghann
authors.initials: M
authors.lastname: Kaiser
authors.forename: Amr
authors.initials: A
authors.lastname: Yafi
authors.forename: Marianne
authors.initials: M
authors.lastname: Cinat
authors.forename: Bernard
authors.initials: B
authors.lastname: Choi
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Durkin
mesh_terms: D002056:Burns / Q000175:diagnosis* / Q000473:pathology; D002196:Capillaries; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D015601:Injury Severity Score; D008833:Microcirculation / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000473:pathology