title: Lipase-catalyzed synthesis of fattythioic acids from palm oil.
abstract: The present work focuses on the synthesis of fattythioic acids (FTAs) by a one-step lipase catalyzed reaction of palm oil with carbonothioic S,S-acid using Lipozyme. The product was characterized using Fourier transform infrared (FTIR) spectroscopy, proton nuclear magnetic resonance ((1)H NMR) technique and elemental analysis. The effects of various reaction parameters such as reaction time, temperature, amount of enzyme, molar ratio of substrates, and various organic solvents of the reaction system were investigated. The optimum conditions to produce FTAs were respectively, incubation time, 20 h, temperature, 40°C, amount of enzyme, 0.05 g and molar ratio of carbonothioic S,S-acid to palm oil, 5.0:1.0. Hexane was the best solvent for this reaction. The conversion of the products at optimum conditions was around 91%.
authors.affiliation: Department of Chemistry, College of Science, University of Kufa, AnNajaf, Iraq. emadaalmulla@yahoo.com
authors.forename: Emad A Jaffar
authors.initials: EA
authors.lastname: Al-Mulla
mesh_terms: D002384:Catalysis / Q000187:drug effects; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism*; D008049:Lipase / Q000378:metabolism* / Q000502:physiology; D008954:Models, Biological; D019906:Nuclear Magnetic Resonance, Biomolecular; D009930:Organic Chemicals / Q000737:chemistry / Q000494:pharmacology; D000073878:Palm Oil; D010938:Plant Oils / Q000378:metabolism*; D012997:Solvents / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared; D013438:Sulfhydryl Compounds / Q000737:chemistry / Q000378:metabolism*
chemical_list: D005227:Fatty Acids; D009930:Organic Chemicals; D010938:Plant Oils; D012997:Solvents; D013438:Sulfhydryl Compounds; D000073878:Palm Oil; D008049:Lipase