title: Corneal Crosslinking for Keratoconus in Iranian Patients: Outcomes at 1 year following treatment.
abstract: OBJECTIVE
  A retrospective, nonrandomized, single-center clinical study was designed to evaluate the outcomes of corneal collagen crosslinking (CXL) for progressive keratoconus in Iranian patients 12 months after CXL.
  
  
  METHODS
  This study was carried out at Navid Didegan Eye Center, a private clinic, Mashhad, Iran.
  
  
  METHODS
  Ninety-two eyes of 53 subjects with progressive keratoconus were evaluated in this study. All eyes completed 1-year follow-up. The outcome measures were uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), sphere and cylinder refraction, keratometry, and corneal thickness. Comparison of baseline and 1-year postoperative data is reported in this study. The Wilcoxon signed-ranked and Student's t-tests were used for statistical analyses. P < 0.05 was statistically significant.
  
  
  RESULTS
  The mean age was 21.5 ± 3.4 years (range, 16 -30 years). Thirty-one (58.5%) of the subjects were men and 22 (41.5%) were women. Mean baseline UCVA and BSCVA were 0.61 ± 0.31 and 0.06 ± 0.12 logarithm of minimal angle of resolution (logMAR), respectively. One year postoperatively UCVA was 0.31 ± 0.25 logMAR and BSCVA was 0.0 ± 0.01 logMAR. UCVA and BSCVA were statistically higher postoperatively (P < 0.001, both parameters). The mean astigmatism decreased by 0.78 ± 1.49 diopter (D) with significant variation during the follow-up period (P < 0.001). Mean baseline simulated keratometry (SIM K) was 46.94 ± 2.37 D and decreased to 46.0 ± 2.33 D on year postoperatively (P < 0.001).
  
  
  CONCLUSIONS
  Corneal CXL seems to be efficient in stabilization of progressive keratoconus progression in Iranian patients at 1 year of followup.
authors.affiliation: Islamic Azad University of Mashhad, Mashhad, Iran.
authors.forename: Ladan
authors.initials: L
authors.lastname: Saffarian
authors.forename: Hamid
authors.initials: H
authors.lastname: Khakshoor
authors.forename: Mehran
authors.initials: M
authors.lastname: Zarei-Ghanavati
authors.forename: Habibollah
authors.initials: H
authors.lastname: Esmaily