title: New Delhi metallo-β-lactamase in Klebsiella pneumoniae and Escherichia coli, Canada.
abstract: Multidrug-resistant Klebsiella pneumoniae and Escherichia coli isolates harboring New Delhi metallo-β-lactamase (NDM-1) were isolated from a patient who had returned to Canada from India. The NDM-1 gene was found on closely related incompatibility group A/C type plasmids. The occurrence of NDM-1 in North America is a major public health concern.
authors.affiliation: Antimicrobial Resistance and Nosocomial Infections section, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. michael.mulvey@phac-aspc.gc.ca
authors.forename: Michael R
authors.initials: MR
authors.lastname: Mulvey
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Grant
authors.forename: Katherine
authors.initials: K
authors.lastname: Plewes
authors.forename: Diane
authors.initials: D
authors.lastname: Roscoe
authors.forename: David A
authors.initials: DA
authors.lastname: Boyd
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002170:Canada / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007194:India; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D014195:Travel; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1