title: Visualization of endolymphatic hydrops in Ménière's disease with single-dose intravenous gadolinium-based contrast media using heavily T(2)-weighted 3D-FLAIR.
abstract: Heavily T(2)-weighted 3-dimensional fluid-attenuated inversion recovery (hT(2)W-3D-FLAIR) technique has been reported to be more sensitive than conventional 3D-FLAIR in detecting low concentrations of gadolinium-based contrast media (GBCM) in fluid. We applied hT(2)W-3D-FLAIR to visualize endolymphatic hydrops of Ménière's disease in 3 patients 4 hours after single-dose intravenous injection of GBCM and successfully visualized endolymphatic hydrops in either the cochlea or vestibule in all patients. This technique can be implemented in a clinical setting.
authors.affiliation: Department of Radiology, Nagoya University Graduate School of Medicine, Shouwa, NAgoya, Japan. naganawa@med.nagoya-u.ac.jp
authors.forename: Shinji
authors.initials: S
authors.lastname: Naganawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamazaki
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kawai
authors.forename: Kiminori
authors.initials: K
authors.lastname: Bokura
authors.forename: Michihiko
authors.initials: M
authors.lastname: Sone
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakashima
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D003051:Cochlea / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D018159:Endolymphatic Hydrops / Q000150:complications / Q000473:pathology*; D005260:Female; D005682:Gadolinium; D006571:Heterocyclic Compounds / Q000008:administration & dosage; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008575:Meniere Disease / Q000150:complications*; D008875:Middle Aged; D015588:Observer Variation; D009942:Organometallic Compounds / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C062402:gadoteridol; D005682:Gadolinium