title: Smiles cascades toward heterocyclic scaffolds.
abstract: Two different Smiles rearrangements can be combined to afford a multicomponent formation of isoquinolinones and isoindolinones from nitro methyl salicylate. After a Ugi-Smiles four-component coupling, the base-triggered cyclization of the resulting adduct is followed by a ring contraction via a Truce-Smiles rearrangement.
authors.affiliation: Laboratoire Chimie et Procédés, Ecole Nationale Supérieure de Techniques Avancées, 32 Bd Victor, 75739 Paris Cedex 15, France. laurent.elkaim@ensta-paristech.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: El Kaim
authors.forename: Laurence
authors.initials: L
authors.lastname: Grimaud
authors.forename: Xavier F
authors.initials: XF
authors.lastname: Le Goff
authors.forename: Aurélie
authors.initials: A
authors.lastname: Schiltz