title: Duchenne muscular dystrophy models show their age.
abstract: The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the pathological progression of human DMD and shows that muscle stem cell activity is a key determinant of disease severity.
authors.affiliation: Departments of Neurology, Medicine, and Biochemistry, University of Washington, Seattle, WA 98195-7720, USA.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Chamberlain