title: Retinocytoma shows lack of response to chemoreduction.
abstract: The authors report a case of retinocytoma showing no response to chemoreduction. A 30-month-old girl presented with Group B multifocal retinoblastoma in the right eye and Group E retinoblastoma in the left eye. After the first cycle of chemotherapy (vincristine [0.9 mg/m(2)], carboplatin [336 mg/m(2)], and etoposide [90 mg/m(2)]), there was remarkable reduction in the tumor size in the left eye, whereas the right eye tumors did not regress and were diagnosed as retinocytomas/retinomas. Retinocytoma/retinoma shows little to no response to chemoreduction.
authors.affiliation: Ocular Oncology Service, Wills Eye Institute, Philadelphia, Pennsylvania, USA.
authors.forename: Jaeyoon
authors.initials: J
authors.lastname: Chung
authors.forename: Kiran
authors.initials: K
authors.lastname: Turaka
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D017679:Cryotherapy; D004948:Esotropia / Q000175:diagnosis; D005047:Etoposide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009366:Neoplasm Seeding; D019572:Retinal Neoplasms / Q000145:classification / Q000188:drug therapy* / Q000473:pathology; D012175:Retinoblastoma / Q000145:classification / Q000188:drug therapy* / Q000556:secondary; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000473:pathology
chemical_list: D014750:Vincristine; D005047:Etoposide; D016190:Carboplatin