title: γ knife stereotactic radiosurgery in the management of cluster headache.
abstract: Gamma knife stereotactic radiosurgery (SRS) has proven to be an effective management approach for trigeminal neuralgia and as a minimally invasive alternative management option for cluster headache (CH). In CH, patients undergo single-session focused irradiation of the trigeminal nerve root (TN), sometimes coupled with irradiation of the sphenopalatine ganglion (SPG) as well. SRS provides early pain relief in most patients, but is associated with trigeminal sensory dysfunction in some patients. In the future, a prospective trial that compares a single target of TN to dual targets of both the TN and SPG may provide further understanding of the value of SRS for CH.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh, Suite B-400, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kano
authors.forename: Douglas
authors.initials: D
authors.lastname: Kondziolka
authors.forename: Ajay
authors.initials: A
authors.lastname: Niranjan
authors.forename: John C
authors.initials: JC
authors.lastname: Flickinger
authors.forename: L Dade
authors.initials: LD
authors.lastname: Lunsford
mesh_terms: D000818:Animals; D003027:Cluster Headache / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D019468:Disease Management; D006801:Humans; D015337:Multicenter Studies as Topic / Q000379:methods; D016634:Radiosurgery / Q000379:methods* / Q000639:trends