title: [Effect of obstructive sleep apnea hypopnea syndrome on arterial stiffness].
abstract: OBJECTIVE
  To assess the effect of obstructive sleep apnea hypopnea syndrome (OSAHS) on brachial-ankle pulse wave velocity (b-aPWV) in untreated diagnosed patients.
  
  
  METHODS
  This study involved 24 consecutive male patients with newly diagnosed untreated OSAHS (aged 39.13±8.31 years) and 22 normal male individuals (aged 39.59±10.86 years) matched for age and body mass index. Carotid and extremities ultrasound were performed in all the subjects, and none of them had atherosclerosis, arterial calcification, or aneurysm. No subject had a history of hypertension, coronary heart disease or stroke. All the subjects underwent arterial stiffness evaluation by means of b-aPWV measurements.
  
  
  RESULTS
  The b-aPWV in OSAHS patients was significantly higher than that in normal subjects (1346.86±123.48 vs 1237.91±84.46, P<0.01), and the rate of positive b-aPWV in OSAHS patients was significantly higher (13/24 vs 1/22, P<0.01).
  
  
  CONCLUSIONS
  The value and positive rate of b-aPWV in OSAHS patients are higher than those in normal people, suggesting increased arterial stiffness in OSAHS patients.
authors.affiliation: Department of Ultrasound, General Hospital of PLA, Beijing, China. wency301@vip.sina.com
authors.forename: Chao-yang
authors.initials: CY
authors.lastname: Wen
authors.forename: Yi-sha
authors.initials: YS
authors.lastname: Tong
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.forename: Yu-zhu
authors.initials: YZ
authors.lastname: Li
authors.forename: Yu-sheng
authors.initials: YS
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Han
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Li
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Xie
authors.forename: Jie
authors.initials: J
authors.lastname: Tang
mesh_terms: D000328:Adult; D055109:Ankle Brachial Index; D001158:Arteries / Q000503:physiopathology*; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology*; D059289:Vascular Stiffness; D055815:Young Adult