title: Fetomaternal transfusion after amniocentesis and cordocentesis.
abstract: OBJECTIVE
  To compare the extent of fetomaternal transfusion after amniocentesis and cordocentesis.
  
  
  METHODS
  Three-hundred and forty-five amniocentesis and 268 cordocentesis were performed for genetic indications. The extent of fetomaternal transfusion was calculated on the basis of the maternal serum alpha-fetoprotein level changes.
  
  
  RESULTS
  The mean fetomaternal transfusion was 6.3 and 62 μL in the amniocentesis and cordocentesis groups, respectively. Transplacental needle passage and longer procedural time were risk factors for fetomaternal transfusion. The frequency of transplacental passage was higher and the procedural time was longer in the cordocentesis group. The fetal loss rate was 1.17% after amniocentesis and 1.2% after cordocentesis, respectively.
  
  
  CONCLUSIONS
  Cordocentesis causes more injury to the extrafetal compartment, which results in a higher level of fetomaternal transfusion. However, though a nearly ten times higher fetomaternal transfusion was observed after cordocentesis, there was no essential difference in pregnancy outcome between the two groups.
authors.affiliation: Departments of Obstetrics and Gynecology, Faculty of Medicine, Albert Szent-Györgyi Medical and Pharmaceutical Center, University of Szeged, Semmelweis u. 1., Szeged 6725, Hungary. Sikovanyecz@freemail.hu
authors.forename: J
authors.initials: J
authors.lastname: Sikovanyecz
authors.forename: E
authors.initials: E
authors.lastname: Horváth
authors.forename: N
authors.initials: N
authors.lastname: Pásztor
authors.forename: A
authors.initials: A
authors.lastname: Keresztúri
authors.forename: J
authors.initials: J
authors.lastname: Szabó
authors.forename: A
authors.initials: A
authors.lastname: Pál
mesh_terms: D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D017218:Cordocentesis / Q000009:adverse effects*; D005260:Female; D005331:Fetomaternal Transfusion / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D055815:Young Adult; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins