title: Biocompatibility of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses in eyes with uveitis having cataract surgery: Long-term follow-up.
abstract: OBJECTIVE
  To evaluate the long-term uveal and capsular biocompatibility of 5 intraocular lenses (IOLs) in eyes with uveitic cataract.
  
  
  METHODS
  Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
  
  
  METHODS
  Comparative case series.
  
  
  METHODS
  Patients with uveitis of various origin were consecutively recruited for cataract surgery (1998-2006) and received 1 of 3 hydrophilic acrylic IOLs (Hydroview, AcrySof MA60BM, or Injectacryl F3000), a silicone IOL (CeeOn 911), or a hydrophilic acrylic IOL with heparin surface modification (BioVue(3)). A 7-year follow-up was performed in the Hydroview, AcrySof, and CeeOn groups. Visual acuity, anterior chamber flare measurements, specular microscopy, biomicroscopy, and fundoscopy were performed postoperatively at 6 months and 1, 2, and 3 years.
  
  
  RESULTS
  The study enrolled 136 eyes of 115 patients. There were no significant differences in anterior chamber flare results between the 5 groups. The Hydroview group had the highest grade and the CeeOn IOL and AcrySof groups had the lowest grade of posterior capsule opacification. The BioVue(3) and Injectacryl IOLs had good uveal biocompatibility. Patients in all groups had better visual acuity postoperatively.
  
  
  CONCLUSIONS
  Overall, patients with uveitis benefited from cataract surgery. The long-term results indicate that all sharp-edged hydrophilic and hydrophobic IOLs performed well in eyes with uveitis. Higher uveal biocompatibility was achieved with the modern hydrophilic acrylic IOLs than with the hydrophobic acrylic IOL. Modern hydrophilic acrylic IOLs seem to be a good option in these cases.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. claudette.abela-formanek@meduniwien.ac.at
authors.forename: Claudette
authors.initials: C
authors.lastname: Abela-Formanek
authors.forename: Michael
authors.initials: M
authors.lastname: Amon
authors.forename: Guenal
authors.initials: G
authors.lastname: Kahraman
authors.forename: Joerg
authors.initials: J
authors.lastname: Schauersberger
authors.forename: Roman
authors.initials: R
authors.lastname: Dunavoelgyi
mesh_terms: D000180:Acrylic Resins; D001672:Biocompatible Materials; D002386:Cataract / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009887:Ophthalmoscopy; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D012826:Silicone Elastomers; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications* / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials; D012826:Silicone Elastomers