title: Transdermal buprenorphine for central neuropathic pain: clinical reports.
abstract: Transdermal buprenorphine is an effective analgesic for a variety of pain conditions. Traditionally, neuropathic pain is treated with medications such as tricyclic antidepressants or anticonvulsants, with opioid medications as second or third-line agents. We present two different painful conditions of presumed neuropathic origin, with complex etiopathogenesis, which were successfully treated with buprenorphine. The results of treatment of these neuropathic pain syndromes with buprenorphine are encouraging, suggesting that it might represent a valid alternative to standard approaches for central neuropathic pain.
authors.affiliation: Department of Anesthesiology and Pain Medicine, University of L'Aquila, L'Aquila, Italy.
authors.forename: Cristiana
authors.initials: C
authors.lastname: Guetti
authors.forename: Chiara
authors.initials: C
authors.lastname: Angeletti
authors.forename: Franco
authors.initials: F
authors.lastname: Marinangeli
authors.forename: Alessandra
authors.initials: A
authors.lastname: Ciccozzi
authors.forename: Giada
authors.initials: G
authors.lastname: Baldascino
authors.forename: Antonella
authors.initials: A
authors.lastname: Paladini
authors.forename: Giustino
authors.initials: G
authors.lastname: Varrassi
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002047:Buprenorphine / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008336:Mandibular Diseases / Q000150:complications / Q000473:pathology; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology; D009460:Neurologic Examination; D010147:Pain Measurement; D011149:Pons / Q000473:pathology; D020521:Stroke / Q000150:complications; D013786:Thalamic Diseases / Q000150:complications; D014147:Tramadol / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D000929:Antidepressive Agents, Tricyclic; D014147:Tramadol; D002047:Buprenorphine