title: [Study on the relationship of high hematocrit with changes of the blood viscosity during in the environment of altitude hypoxia].
abstract: OBJECTIVE
  To investigate the relationship of high hematocrit with changes of the blood viscosity during in the environment of altitude hypoxia.
  
  
  METHODS
  Index of hemorheology was determined from populations with different time of inhabit highland and normal controls.
  
  
  RESULTS
  (1) Hematocrit and RBC deformability were higher in all highland populations than that in normal controls, these increase were time-dependent. (2) The blood viscosity was increased significantly during the early stage of inhabit highland, and restored normal in late stage. (3) RBC aggregability was reduced significantly with time-dependent in highland populations. (4) The oxygen content of tissue was reduced significantly during the early stage of inhabit highland, and restored normal in late stage.
  
  
  CONCLUSIONS
  In the environment of altitude hypoxia, RBC deformability increase and RBC aggregability decrease can suppress blood viscosity increase induced by erythrocytosis, these compensatory regulation is help to maintain the normal oxygen content of tissue.
authors.affiliation: Shanghai Provincial Corps Hospital, Chinese People's Armed Police Forces, Shanghai 201103, China.
authors.forename: S K
authors.initials: SK
authors.lastname: Cheng
authors.forename: J Y
authors.initials: JY
authors.lastname: Yu
authors.forename: B H
authors.initials: BH
authors.lastname: Si
authors.forename: Q L
authors.initials: QL
authors.lastname: Xiao
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000531:Altitude; D001809:Blood Viscosity; D006400:Hematocrit; D006801:Humans; D000860:Hypoxia; D008297:Male; D008875:Middle Aged; D011086:Polycythemia; D055815:Young Adult