title: Suitability and calibration of a rebound tonometer to measure IOP in rabbit and pig eyes.
abstract: OBJECTIVE
  To utilize the Icare tonometer TAO1 for intraocular pressure (IOP) determination in experimental animals. To calculate true IOP calibration functions for rabbit and porcine eyes.
  
  
  METHODS
  Enucleated eyes of 3-year-old healthy experimental rabbits (New Zealand white), and healthy 1 year old experimental pigs (Deutsche Landrasse) were used for the determination of IOP.
  
  
  METHODS
  Manometric (Geuder GmbH, Heidelberg/Germany) and rebound tonometry (Icare tonometer TAO1, Icare, Helsinki/Finland) were used to record IOP in enucleated animal eyes (rabbit n=2, pig n=3).
  
  
  RESULTS
  The Icare tonometer TAO1 measurements underestimated true IOP by 37-60% in rabbit eyes and 17-63% in porcine eyes. IOP values obtained by both rebound and manometric tonometry for rabbit and porcine eyes followed a linear regression curve. Linear functions were calculated to correct the Icare tonometer TAO1 measurements to true IOP for both rabbit (p=1.4244p(ic) + 4.2421) and porcine eyes (p=1.0799p(ic) + 5.8557).
  
  
  CONCLUSIONS
  The Icare tonometer TAO1 can be utilized for IOP determination in rabbit and porcine eyes when measured values are corrected with the appropriate linear function.
authors.affiliation: Universität Rostock, Institut für Biomedizinische Technik, Friedrich-Barnwitz Str. 4, Rostock. marian.loebler@unirostock.de
authors.forename: Marian
authors.initials: M
authors.lastname: Löbler
authors.forename: Annelie
authors.initials: A
authors.lastname: Rehmer
authors.forename: Rudolf
authors.initials: R
authors.lastname: Guthoff
authors.forename: Heiner
authors.initials: H
authors.lastname: Martin
authors.forename: Katrin
authors.initials: K
authors.lastname: Sternberg
authors.forename: Oliver
authors.initials: O
authors.lastname: Stachs
mesh_terms: D000818:Animals; D002138:Calibration; D007429:Intraocular Pressure / Q000502:physiology*; D011817:Rabbits; D013552:Swine / Q000502:physiology*; D014065:Tonometry, Ocular / Q000295:instrumentation / Q000592:standards