title: Using click chemistry to access mono- and ditopic β-cyclodextrin hosts substituted by chiral amino acids.
abstract: A wide range of chiral mono- and ditopic cyclodextrin-based receptors have been synthesized by CuI-catalyzed azide-alkyne cycloaddition starting from mono-6-azido-β-cyclodextrin and chiral amino acids. Of interest, microwaves proved very efficient to access a wide range of ditopic β-cyclodextrin receptors with quantitative yields.
authors.affiliation: Univ Lille Nord de France, F-59000 Lille, France.
authors.forename: Diem Ngan
authors.initials: DN
authors.lastname: Tran
authors.forename: Claire
authors.initials: C
authors.lastname: Blaszkiewicz
authors.forename: Stéphane
authors.initials: S
authors.lastname: Menuel
authors.forename: Alain
authors.initials: A
authors.lastname: Roucoux
authors.forename: Karine
authors.initials: K
authors.lastname: Philippot
authors.forename: Frédéric
authors.initials: F
authors.lastname: Hapiot
authors.forename: Eric
authors.initials: E
authors.lastname: Monflier
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D057930:Click Chemistry / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D047392:beta-Cyclodextrins; D003300:Copper