title: A preliminary report of a Phase II study of folinic acid, 5-fluorouracil, irinotecan (FOLFIRI) plus sunitinib with toxicity, efficacy, pharmacokinetics, biomarker, imaging data in patients with colorectal cancer with liver metastases as 1st line treatment.
authors.affiliation: Tumor Biology Center at the Albert-Ludwigs-University Freiburg,Germany. mross@tumorbio.uni-freiburg.de
authors.forename: K
authors.initials: K
authors.lastname: Mross
authors.forename: M
authors.initials: M
authors.lastname: Büchert
authors.forename: U
authors.initials: U
authors.lastname: Fasol
authors.forename: U
authors.initials: U
authors.lastname: Jaehde
authors.forename: F
authors.initials: F
authors.lastname: Kanefendt
authors.forename: D
authors.initials: D
authors.lastname: Strumberg
authors.forename: J
authors.initials: J
authors.lastname: Arends
authors.forename: J
authors.initials: J
authors.lastname: Hense
authors.forename: B
authors.initials: B
authors.lastname: Moritz
authors.forename: R
authors.initials: R
authors.lastname: Fischer
authors.forename: M E
authors.initials: ME
authors.lastname: Scheulen
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis; D002166:Camptothecin / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005472:Fluorouracil / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002955:Leucovorin / Q000009:adverse effects / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D011758:Pyrroles / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000077210:Sunitinib
chemical_list: D014408:Biomarkers, Tumor; D007211:Indoles; D011758:Pyrroles; D002955:Leucovorin; D005472:Fluorouracil; D000077210:Sunitinib; D002166:Camptothecin