title: [Role of Helicobacter pylori infection in iron deficiency anemia].
abstract: Anemia induced by digestive diseases refers to anemia due to iron deficiency. Conventional gastrointestinal diagnostic workup fails to establish the cause of iron deficiency in about one third of patients. Abnormal iron absorption is increasingly recognized as an important cause of unexplained iron deficiency. The importance of coeliac disease as a possible cause of iron deficiency anemia refractory to oral iron treatment, without other manifestations of malabsorption syndrome, is increasingly being recognized. In addition, Helicobacter pylori (HP) has been implicated in several recent studies as a cause of iron deficiency anemia (IDA) refractory to oral iron treatment. Cure of previously refractory IDA by HP eradication provides strong evidence supporting a cause-and-effect relationship. In order to establish a cause-and-effect relationship between HP gastritis and IDA, prospective randomized studies comparing the effects of iron administration with or without H. pylorieradication are highly recommended.
authors.affiliation: Centre hospitalo-universitaire (CHU) de Monastir, Monastir 5000, Tunisie. nabilca@yahoo.fr
authors.forename: Nabil Ben
authors.initials: NB
authors.lastname: Chaabane
authors.forename: Imed Ben
authors.initials: IB
authors.lastname: Mansour
authors.forename: Olfa
authors.initials: O
authors.lastname: Hellara
authors.forename: Hichem
authors.initials: H
authors.lastname: Loghmeri
authors.forename: Fethia
authors.initials: F
authors.lastname: Bdioui
authors.forename: Leila
authors.initials: L
authors.lastname: Safer
authors.forename: Hamouda
authors.initials: H
authors.lastname: Saffar
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005756:Gastritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016481:Helicobacter Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D007223:Infant; D007501:Iron / Q000008:administration & dosage / Q000097:blood; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors; D007501:Iron