title: Collagenofibrotic glomerulopathy in association with Hodgkin's lymphoma.
abstract: Deposit glomerulopathies are characterized by fibrillary deposits of various sizes, mainly in the mesangial area. Collagenofibrotic glomerulopathy is a rare type of such fibrillary glomerulopathies characterized by deposits of 60-80 nm fibrils in the sub-endothelial and mesangial areas. It is also associated with increased levels of serum pro-collagen type III peptide (PIIINP). Although most of the initial reports have emanated from Japan, many other scientists around the globe have later reported this disease. Possibility of systemic disease affecting metabolism of type III collagen is postulated but so far no such association has been identified. We report a 26-year-old male patient who presented with insidious onset of febrile illness associated with lymphadenopathy and proteinuria. Lymph node biopsy revealed features of Hodgkin's lymphoma while percutaneous renal biopsy showed features of collagenofibrotic glomerulopathy.
authors.affiliation: Department of Nephrology, Mediciti Hospitals, Aurangabad, Maharashtra, India.
authors.forename: Sachin S
authors.initials: SS
authors.lastname: Soni
authors.forename: Swarnalata
authors.initials: S
authors.lastname: Gowrishankar
authors.forename: Amit P
authors.initials: AP
authors.lastname: Nagarik
authors.forename: Sriganesh R
authors.initials: SR
authors.lastname: Barnela
authors.forename: Michelle
authors.initials: M
authors.lastname: De Padua
authors.forename: Gopal Kishan
authors.initials: GK
authors.lastname: Adikey
authors.forename: Anuradha
authors.initials: A
authors.lastname: Raman
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D003094:Collagen / Q000032:analysis*; D005334:Fever / Q000209:etiology; D005355:Fibrosis; D005921:Glomerulonephritis / Q000097:blood / Q000150:complications / Q000473:pathology*; D006689:Hodgkin Disease / Q000097:blood / Q000150:complications / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000737:chemistry / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D010446:Peptide Fragments / Q000097:blood; D011347:Procollagen / Q000097:blood; D011507:Proteinuria / Q000209:etiology
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; D011347:Procollagen; C041876:procollagen Type III-N-terminal peptide; D003094:Collagen