title: Stem cell infusion into the vein of Marshall.
abstract: The vein of Marshall (VOM) and related cardiac ganglia have been clearly implicated in atrial fibrillation. Electrophysiological procedures have targeted these sites of autonomic innervation. However, targeting the exact sites has proven technically challenging. Identifying the VOM and infusing stem cells may ablate related ganglia autonomic function and offer an innovative treatment for atrial fibrillation.
authors.affiliation: Department of Cardiology, Royal Brompton Hospital, Sydney Street, Chelsea, London SW3 6NP, UK. j.lyne@rbht.nhs.uk
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Lyne
authors.forename: Amanda C
authors.initials: AC
authors.lastname: Green
authors.forename: Eric W
authors.initials: EW
authors.lastname: Alton
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Clague
mesh_terms: D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D017023:Coronary Angiography; D003331:Coronary Vessels; D005724:Ganglia / Q000502:physiology; D006321:Heart / Q000294:innervation; D006329:Heart Conduction System / Q000503:physiopathology; D006333:Heart Failure / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D016896:Treatment Outcome