title: Comparison of 2% chlorhexidine and 5.25% sodium hypochlorite irrigating solutions on postoperative pain: a randomized clinical trial.
abstract: OBJECTIVE
  To compare the levels of postoperative pain after cleaning and shaping of root canals using two different root canal irrigants for debridement.
  
  
  METHODS
  Forty patients with irreversible pulpitis, pulp necrosis and non-vital teeth exhibiting acute apical periodontitis requiring root canal treatment were included. At random, canals were cleaned and shaped with the following protocols. 2% chlorhexidine solution in group I and 5.25% sodium hypochlorite solution in group II were used as an irrigants. Access cavities were closed with a sterile cotton pellet and cavit. The patients recorded degree of pain at various time intervals after cleaning and shaping on a visual analogue scale for 1 week.
  
  
  RESULTS
  The mean pain score for group I was between 0.65 and 3.35 and for group II was between 0.95 and 4.50. There was significant difference in the pain level between the two groups only at 6 th hour postoperatively (P<0.05) and the pain was more in sodium hypochlorite group.
  
  
  CONCLUSIONS
  More pain was present in teeth irrigated using 5.25% sodium hypochlorite when compared to that in teeth irrigated using 2% chlorhexidine solution. Significant difference in pain level was present only at 6th hour postoperatively, and at all other periods (24 th hour, 4 th and 7 th days) there was no significant difference in pain level between the two groups.
authors.affiliation: Department of Conservative Dentistry & Endodontics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India. drbashetty@gmail.com
authors.forename: Kusum
authors.initials: K
authors.lastname: Bashetty
authors.forename: Jayshree
authors.initials: J
authors.lastname: Hegde
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002133:Calcium Sulfate / Q000627:therapeutic use; D002710:Chlorhexidine / Q000627:therapeutic use*; D003738:Dental Cements / Q000627:therapeutic use; D003790:Dental Pulp Necrosis / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010485:Periapical Periodontitis / Q000628:therapy; D011145:Polyvinyls / Q000627:therapeutic use; D011671:Pulpitis / Q000628:therapy; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D018915:Root Canal Preparation / Q000379:methods*; D012973:Sodium Hypochlorite / Q000627:therapeutic use*; D019553:Tooth, Nonvital / Q000628:therapy; D055815:Young Adult; D015034:Zinc Oxide / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D003738:Dental Cements; D011145:Polyvinyls; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; C020872:Cavit; D012973:Sodium Hypochlorite; D002710:Chlorhexidine; D015034:Zinc Oxide; D002133:Calcium Sulfate