title: Seeking resolution: budding yeast enzymes finally make the cut.
abstract: Genetic studies reported in Molecular Cell (Ho et al., 2010) identify Mus81-Mms4 and Yen1 as the structure-specific endonucleases that cleave most Holliday junctions. A failure in this key step has profound effects on mitotic genome stability.
authors.affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. sue.robertson@duke.edu
authors.forename: Sue
authors.initials: S
authors.lastname: Jinks-Robertson