title: Reduced bowel sounds in Parkinson's disease and multiple system atrophy patients.
abstract: Digital auscultation of bowel sounds was performed in newly diagnosed, drug-naïve patients with Parkinson's disease (PD) (n = 10), multiple system atrophy (MSA) (n = 12), progressive supranuclear palsy/corticobasal degeneration (PSP/CBD) (n = 7), and control subjects (n = 18). The number of bowel sounds per minute and the integrated time of bowel sounds were significantly lower in PD and MSA patients than in control subjects. Reduced bowel sounds may herald compromised gastrointestinal motility in patients with PD and MSA.
authors.affiliation: Department of Neurology, Niigata University Brain Research Institute, 1-757 Asahimachi, Chuo-ku, Niigata, 951-8585, Japan. ozawa@bri.niigata-u.ac.jp
authors.forename: Tetsutaro
authors.initials: T
authors.lastname: Ozawa
authors.forename: Etsuji
authors.initials: E
authors.lastname: Saji
authors.forename: Ryuji
authors.initials: R
authors.lastname: Yajima
authors.forename: Osamu
authors.initials: O
authors.lastname: Onodera
authors.forename: Masatoyo
authors.initials: M
authors.lastname: Nishizawa
mesh_terms: D000368:Aged; D001314:Auscultation / Q000379:methods; D016022:Case-Control Studies; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology; D041981:Gastrointestinal Tract / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology*; D013016:Sound; D013494:Supranuclear Palsy, Progressive / Q000503:physiopathology