title: First identification and characterization of an AdeABC-like efflux pump in Acinetobacter genomospecies 13TU.
abstract: Non-Acinetobacter baumannii spp. are emerging among clinical Acinetobacter isolates causing nosocomial infections, and some (such as genomospecies 13TU) appear to be multidrug resistant. The prevalence of non-Acinetobacter baumannii spp. in the hospital setting is likely understated due to poor identification techniques. We report the first identification of an AdeABC-type efflux pump in an Acinetobacter genomospecies 13TU clinical isolate, its contribution to multidrug resistance, and the coexistence of three Ade-type efflux pumps in this strain.
authors.affiliation: Department of Microbiology, Hospital Clínic, School of Medicine, University of Barcelona, CRESIB, Barcelona, Spain.
authors.forename: Ignasi
authors.initials: I
authors.lastname: Roca
authors.forename: Paula
authors.initials: P
authors.lastname: Espinal
authors.forename: Sara
authors.initials: S
authors.lastname: Martí
authors.forename: Jordi
authors.initials: J
authors.lastname: Vila
mesh_terms: D000150:Acinetobacter / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D026901:Membrane Transport Proteins