title: [Lynch syndrome: genetics and surgery].
abstract: Hereditary nonpolyposis colorectal cancer or Lynch Syndrome, caused by germinal mutations in mismatch deoxyribonucleic acid (DNA) repair genes, is the most common form of hereditary colorectal cancer. The identification of these individuals is not easy and is based on clinical and molecular criteria. A review is presented on the genetics and diagnosis in Lynch Syndrome, as well as on its surgical management and prevention.
authors.affiliation: Hospital Torrecárdenas, Almería, España. manuferrer78@hotmail.com
authors.forename: Manuel Ferrer
authors.initials: MF
authors.lastname: Márquez
authors.forename: Angel Reina
authors.initials: AR
authors.lastname: Duarte
authors.forename: Vanesa Maturana
authors.initials: VM
authors.lastname: Ibáñez
authors.forename: Ricardo Belda
authors.initials: RB
authors.lastname: Lozano
authors.forename: Francisco Rubio
authors.initials: FR
authors.lastname: Gil
authors.forename: Isabel Blesa
authors.initials: IB
authors.lastname: Sierra
authors.forename: María del Mar Rico
authors.initials: Mdel M
authors.lastname: Morales
mesh_terms: D000465:Algorithms; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery*; D006801:Humans