title: Intralesional mitomycin-C for the treatment of conjunctival Kaposi sarcoma.
abstract: A 38-year-old human immunodeficiency virus-positive man presented with a progressively enlarging pigmented lesion in the right inferior fornix of the eye. A biopsy was performed of this lesion, which revealed Kaposi sarcoma. Intralesional mitomycin-C was delivered to the lesion, resulting in complete resolution of the sarcoma. At 36 months of follow-up, there is no evidence of recurrence. To the best of our knowledge, this is the first report of successful treatment of conjunctival Kaposi sarcoma with intralesional mitomycin-C.
authors.affiliation: Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093-0946, USA. bkorn@ucsd.edu
authors.forename: Bobby S
authors.initials: BS
authors.lastname: Korn
authors.forename: D J John
authors.initials: DJ
authors.lastname: Park
authors.forename: Don O
authors.initials: DO
authors.lastname: Kikkawa
mesh_terms: D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D003230:Conjunctival Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005500:Follow-Up Studies; D006679:HIV Seropositivity / Q000473:pathology*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage*; D012514:Sarcoma, Kaposi / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin