title: Lifestyle challenges in endometrial cancer survivorship.
abstract: OBJECTIVE
  To examine lifestyle behaviors that may contribute to endometrial cancer survivor morbidity and to identify associations with quality of life.
  
  
  METHODS
  Patients with early-stage (I or II) endometrial cancer with a body mass index of at least 25 kg/m2 completed questionnaires on smoking, physical activity, fruit and vegetable intake, and the Functional Assessment of Cancer Therapy (FACT) and Short-Form medical outcomes (SF-36) quality-of-life surveys. Behaviors were compared with American Cancer Society 2006 guidelines for cancer survivors (150 min/wk of moderate-to-vigorous physical activity; five servings fruit and vegetables per day; no smoking). Effect size (d) was calculated for the difference in means between meeting and not meeting guidelines (d=0.5 moderate effect).
  
  
  RESULTS
  A total of 120 participants were enrolled. Of those, 43% had hypertension, 35% osteoarthritis, 33% metabolic syndrome, 21% type 2 diabetes mellitus, and 93% abdominal obesity. Only 12% of participants were meeting physical activity guidelines. Fifteen percent reported five or more servings of fruit and vegetables per day; mean intake was 2.6 servings per day. Seventy-four percent of participants were nonsmokers. Only 1% of participants met all three American Cancer Society guidelines; 22% met none of the recommendations. The emotional well-being (mean 17.4 [±4.1] compared with 20.1 [±4.1]; d=0.66) and fatigue scores (mean 34.6 [±9.5] compared with 40.5 [±9.6]; d=0.62) indicate that those who do not meet the guidelines had lower emotional well-being and increased fatigue.
  
  
  CONCLUSIONS
  Endometrial cancer survivors have unhealthy lifestyles that put them at risk for morbidity. This survivor group should be offered multi-behavioral lifestyle interventions after diagnosis.
  
  
  BACKGROUND
  ClinicalTrials.gov, www.clinicaltrials.gov, NCT 00420979 and NCT00732173.
  
  
  METHODS
  II.
authors.affiliation: From Summa Health System/Akron City Hospital, Akron, Ohio; University Hospitals Case Medical Center, Cleveland, Ohio; Case Western Reserve University, Cleveland, Ohio; Cleveland Clinic, Cleveland, Ohio; and the University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Vivian E
authors.initials: VE
authors.lastname: von Gruenigen
authors.forename: Steven E
authors.initials: SE
authors.lastname: Waggoner
authors.forename: Heidi E
authors.initials: HE
authors.lastname: Frasure
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Kavanagh
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Janata
authors.forename: Peter G
authors.initials: PG
authors.lastname: Rose
authors.forename: Kerry S
authors.initials: KS
authors.lastname: Courneya
authors.forename: Edith
authors.initials: E
authors.lastname: Lerner
mesh_terms: D000368:Aged; D016889:Endometrial Neoplasms / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D011446:Prospective Studies