title: Heat profiling of three-dimensionally optically trapped gold nanoparticles using vesicle cargo release.
abstract: Irradiated metallic nanoparticles hold great promise as heat transducers in photothermal applications such as drug delivery assays or photothermal therapy. We quantify the temperature increase of individual gold nanoparticles trapped in three dimensions near lipid vesicles exhibiting temperature sensitive permeability. The surface temperature can increase by hundreds of degrees Celsius even at moderate laser powers. Also, there are significant differences of the heat profiles in two-dimensional and three-dimensional trapping assays.
authors.affiliation: Niels Bohr Institute, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Anders
authors.initials: A
authors.lastname: Kyrsting
authors.forename: Poul M
authors.initials: PM
authors.lastname: Bendix
authors.forename: Dimitrios G
authors.initials: DG
authors.lastname: Stamou
authors.forename: Lene B
authors.initials: LB
authors.lastname: Oddershede
mesh_terms: D004058:Diffusion; D006046:Gold / Q000737:chemistry*; D006358:Hot Temperature; D008081:Liposomes / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008968:Molecular Conformation; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure*; D053758:Nanoparticles / Q000737:chemistry*; D052898:Optical Tweezers; D013499:Surface Properties
chemical_list: D008081:Liposomes; D046911:Macromolecular Substances; D053769:Nanocapsules; D006046:Gold