title: [Cardiovascular manifestations in Chinese patients with hypereosinophilic syndrome].
abstract: OBJECTIVE
  To evaluate the cardiovascular involvements in Chinese patients with hypereosinophilic syndrome.
  
  
  METHODS
  We respectively reviewed 149 inpatients with hypereosinophilic syndrome admitted to Peking Union Medical College Hospital and analyzed the cardiovascular involvements in these patients.
  
  
  RESULTS
  Cardiac abnormalities was evidenced in 32.9% patients (49/149). The ratio of male vs female was 34:15. The average age of the patients was (41.3 ± 16.9) years and course of disease was (26.4 ± 72.3) months. Cardiovascular involvements included ST segment and/or T wave (ST-T) ischemic changes, arrhythmia, myocardial injury, cardiac thrombosis, pericardial effusion, pulmonary hypertension, valve disorder, vein or artery thrombosis. After glucocorticoid and/or chemotherapeutic agents and treatment for symptoms, 11 (22.4%) patients achieved remission but have recurrent attacks and 3 (6.1%) patients died from failure in treatment. The prognosis in patients with echocardiogram abnormalities were poorer than those only with electrocardiogram abnormalities (P < 0.05).
  
  
  CONCLUSIONS
  Cardiovascular involvements are common in patients with hypereosinophilic syndrome and the manifestation of these involvement is various. Cardiovascular complications of HES are a major source of morbidity and mortality in these disorders.
authors.affiliation: Department of Cardiology, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Rui-yi
authors.initials: RY
authors.lastname: Xu
authors.forename: Li-lin
authors.initials: LL
authors.lastname: Guo
authors.forename: Xue
authors.initials: X
authors.lastname: Lin
authors.forename: Li-gang
authors.initials: LG
authors.lastname: Fang
authors.forename: Quan
authors.initials: Q
authors.lastname: Fang
authors.forename: Xiao-wei
authors.initials: XW
authors.lastname: Yan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D007223:Infant; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D014463:Ultrasonography; D055815:Young Adult