title: End-stapled homo and hetero collagen triple helices: a click chemistry approach.
abstract: A CuAAC reaction was established for modular synthesis of end-stapled homo- and hetero-triple helical peptides, generating "clicked" macro-assemblies with enhanced thermal stability.
authors.affiliation: School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK.
authors.forename: Cillian
authors.initials: C
authors.lastname: Byrne
authors.forename: Paul A
authors.initials: PA
authors.lastname: McEwan
authors.forename: Jonas
authors.initials: J
authors.lastname: Emsley
authors.forename: Peter M
authors.initials: PM
authors.lastname: Fischer
authors.forename: Weng C
authors.initials: WC
authors.lastname: Chan
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000595:Amino Acid Sequence; D001386:Azides / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D002384:Catalysis; D002942:Circular Dichroism; D057930:Click Chemistry; D003094:Collagen / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D003300:Copper; D003094:Collagen