title: Discussion: 'Testing for biomarkers after ASC-US Pap smears' by Lin et al.
abstract: In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed: Lin CJ, Lai H-C, Wang KH, et al. Testing for methylated PCDH10 or WT1 is superior to the HPV test in detecting severe neoplasms (CIN3 or greater) in the triage of ASC-US smear results. Am J Obstet Gynecol 2011;204:21.e1-7.
authors.affiliation: Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
authors.forename: George A
authors.initials: GA
authors.lastname: Macones
authors.forename: Anthony
authors.initials: A
authors.lastname: Odibo
authors.forename: Alison
authors.initials: A
authors.lastname: Cahill
authors.forename: David
authors.initials: D
authors.lastname: Stamilio
mesh_terms: D015820:Cadherins / Q000235:genetics; D019175:DNA Methylation; D057890:Epigenomics / Q000379:methods*; D005260:Female; D016162:Genes, Wilms Tumor; D005819:Genetic Markers; D006801:Humans; D051761:Paired Box Transcription Factors / Q000235:genetics; D011230:Precancerous Conditions / Q000175:diagnosis / Q000235:genetics* / Q000821:virology; D000091363:Protocadherins; D018401:Sample Size; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000821:virology; D014626:Vaginal Smears
chemical_list: D015820:Cadherins; D005819:Genetic Markers; C438603:PCDH10 protein, human; D051761:Paired Box Transcription Factors; D000091363:Protocadherins; C070835:PAX1 transcription factor