title: Insulin resistance and the metabolic syndrome in obese children referred to an obesity center.
abstract: OBJECTIVE
  The aim of this study was to describe insulin resistance and the metabolic syndrome in obese children and adolescents.
  
  
  METHODS
  The cohort consisted of 518 patients, 250 boys, 268 girls, age +/- sd: 11.8 +/- 3.2 years, BMIsds +/- sd: 2.94 +/- 0.5. A standard OGTT was performed.
  
  
  RESULTS
  Impaired glucose tolerance was found in 9.4% of the boys and 5.5% of the girls. Impaired fasting glucose was found in 12.4% of the boys and 11.6% of the girls. The metabolic syndrome was present in 13.9% of children of 10 years or older. The proportion in which the metabolic syndrome was diagnosed was essentially not altered when pubertal groups were used instead of age groups.
  
  
  CONCLUSIONS
  Both impaired fasting glucose and impaired glucose tolerance as well as the metabolic syndrome are highly prevalent among obese children and adolescents.
authors.affiliation: Department of Pediatrics, VU University Medical Center, Amsterdam, Netherlands. J.Rotteveel@Vumc.nl
authors.forename: J
authors.initials: J
authors.lastname: Rotteveel
authors.forename: A
authors.initials: A
authors.lastname: Felius
authors.forename: M M
authors.initials: MM
authors.lastname: van Weissenbruch
authors.forename: H A
authors.initials: HA
authors.lastname: Delemarre-Van de Waal
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D005215:Fasting / Q000378:metabolism; D005260:Female; D018149:Glucose Intolerance; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology*; D009765:Obesity / Q000150:complications*; D012017:Referral and Consultation