title: Role of ezetimibe in the prevention of cardiovascular disease: absence of evidence.
abstract: Ezetimibe is a lipid-lowering agent that inhibits intestinal absorption of dietary cholesterol. It substantially lowers low-density lipoprotein cholesterol levels when used alone or in combination with statins. Although there is a growing push for the continued use of ezetimibe for the prevention of cardiovascular disease, ezetimibe studies available so far are inconsistent, without allowing use of the drug with confidence.
authors.affiliation: Comando Brigata Alpina "Julia", Udine, Italy. lumasci@libero.it
authors.forename: Luca
authors.initials: L
authors.lastname: Mascitelli
authors.forename: Francesca
authors.initials: F
authors.lastname: Pezzetta
authors.forename: Mark R
authors.initials: MR
authors.lastname: Goldstein
mesh_terms: D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D001384:Azetidines / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D008078:Cholesterol, LDL / Q000097:blood; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D000069438:Ezetimibe; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use
chemical_list: D000924:Anticholesteremic Agents; D001384:Azetidines; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000069438:Ezetimibe