title: Comparison of plaque prolapse in consecutive patients treated with Xience V and Taxus Liberte stents.
abstract: The purpose of this article is to investigate the prevalence of plaque prolapse (PP) after Xience V and Taxus Liberte stent implantation. During the study period 2006-2007, 200 consecutive patients underwent coronary revascularization for de novo lesions and received an intravascular ultrasound (IVUS) post-stenting evaluation, (n = 124 patients with Taxus Liberte and n = 76 with Xience V) (227 stent segments). Cross-sectional and longitudinal 3D IVUS images were analyzed in a blind fashion, evaluating the prevalence of PP and calculating its depth and angle. The angulation degree of the coronary artery at the lesion site pre-stent implantation was also evaluated by angiography. The prevalence of PP was 23.9% in Xience V versus 38.1% in Taxus Liberte (P = 0.025). The depth and angle of PP were greater in Taxus Liberte stent than Xience V stent (0.4 ± 0.1 mm versus 0.5 ± 0.2 mm, P = 0.004; and 32.0 ± 8.9° versus 44.6 ± 27.6°, P = 0.044, respectively). The angulation degree of the coronary artery at the lesion site was higher in presence of plaque prolapse than in its absence (48.2 ± 29.3° vs. 38.2 ± 28.1°, P = 0.013). By multivariate analysis, stent type was independently associated with incidence of plaque prolapse. Xience V stent has less plaque prolapse than Taxus Liberte stent. Stent design may play a role in the prevalence of plaque prolapse.
authors.affiliation: Thoraxcenter, Erasmus Medical Center, Ba-583, 's-Gravendijkwal 230, 3015, CE, Rotterdam, The Netherlands.
authors.forename: Zhu Jun
authors.initials: ZJ
authors.lastname: Shen
authors.forename: Salvatore
authors.initials: S
authors.lastname: Brugaletta
authors.forename: Hector M
authors.initials: HM
authors.lastname: Garcia-Garcia
authors.forename: Jurgen
authors.initials: J
authors.lastname: Ligthart
authors.forename: Josep
authors.initials: J
authors.lastname: Gomez-Lara
authors.forename: Roberto
authors.initials: R
authors.lastname: Diletti
authors.forename: Giovanna
authors.initials: G
authors.lastname: Sarno
authors.forename: Karen
authors.initials: K
authors.lastname: Witberg
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D002317:Cardiovascular Agents / Q000008:administration & dosage*; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D058226:Plaque, Atherosclerotic / Q000000981:diagnostic imaging*; D015995:Prevalence; D016037:Single-Blind Method; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods
chemical_list: D002317:Cardiovascular Agents