title: The importance of taking a history of over-the-counter medication use: a brief review and case illustration of "PRN" antihistamine dependence in a hospitalized adolescent.
abstract: Over-the-counter (OTC) and prescription medication abuse has been rapidly increasing, yet publications on OTC abuse in adolescents are limited. We present a brief literature review and a novel report of antihistamine dependence emerging after admission in an adolescent, subsequently treated with naltrexone. This case highlights the need to take a thorough history of OTC, herbal, and prescription drug use from parents and patients separately and repeatedly, at initial presentation, and again if withdrawal symptoms emerge. General strategies for combating OTC and prescription abuse are given.
authors.affiliation: Department of Psychiatry, Nationwide Children's Hospital/The Ohio State University, Columbus, Ohio 43205, USA. Barbara.gracious@nationwidechildrens.org
authors.forename: Barbara
authors.initials: B
authors.lastname: Gracious
authors.forename: Naomi
authors.initials: N
authors.lastname: Abe
authors.forename: Jane
authors.initials: J
authors.lastname: Sundberg
mesh_terms: D000293:Adolescent; D005260:Female; D006634:Histamine H1 Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006919:Hydroxyzine / Q000008:administration & dosage / Q000009:adverse effects*; D008487:Medical History Taking / Q000379:methods*; D009271:Naltrexone / Q000627:therapeutic use; D009292:Narcotic Antagonists / Q000627:therapeutic use; D004366:Nonprescription Drugs / Q000008:administration & dosage / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000534:rehabilitation
chemical_list: D006634:Histamine H1 Antagonists; D009292:Narcotic Antagonists; D004366:Nonprescription Drugs; D006919:Hydroxyzine; D009271:Naltrexone