title: Solar urticaria unresponsive to intravenous immunoglobulins.
abstract: The treatment of solar urticaria (SU) can be difficult. Only a few cases of SU have been treated with intravenous immunoglobulins (IVIg) (as monotherapy or combined with phototherapy), with reported fast and durable increase of solar exposure tolerance. A 61-year-old female with severe UVB- and UVA-induced SU and a 62-year-old female with severe UVA and visible light-induced SU were both treated with a single course of IVIg (total dose of 2 g/kg), infused over 3 days. Phototest, performed 3 months after the treatment, showed only a slight minimal urticating dose improvement, and both patients reported just a moderate and 'transient' subjective improvement. Our patient's poorer response, compared with previous reports, may be due to differences in IVIg's treatment schedules, which are reviewed.
authors.affiliation: Department of Dermatology, Hospital Universitario de La Princesa, Fundación de Investigación Biomédica, Madrid, Spain. mar.llamasvelasco@gmail.com
authors.forename: Mar
authors.initials: M
authors.lastname: Llamas-Velasco
authors.forename: Diego De
authors.initials: DD
authors.lastname: Argila
authors.forename: Cristina
authors.initials: C
authors.lastname: Eguren
authors.forename: Patricia
authors.initials: P
authors.lastname: García-Martin
authors.forename: Sara
authors.initials: S
authors.lastname: Ibañes
authors.forename: Amaro
authors.initials: A
authors.lastname: García-Diez
mesh_terms: D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D007167:Immunotherapy; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000188:drug therapy*; D016896:Treatment Outcome; D014581:Urticaria / Q000188:drug therapy*
chemical_list: D016756:Immunoglobulins, Intravenous