title: Pressure effects on lipid membrane structure and dynamics.
abstract: The effect of hydrostatic pressure on lipid structure and dynamics is highly important as a tool in biophysics and bio-technology, and in the biology of deep sea organisms. Despite its importance, high hydrostatic pressure remains significantly less utilised than other thermodynamic variables such as temperature and chemical composition. Here, we give an overview of some of the theoretical aspects which determine lipid behaviour under pressure and the techniques and technology available to study these effects. We also summarise several recent experiments which highlight the information available from these approaches.
authors.affiliation: Membrane Biophysics Platform and Institute of Chemical Biology, Department of Chemistry, Imperial College London, South Kensington Campus, UK.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Brooks
authors.forename: Oscar
authors.initials: O
authors.lastname: Ces
authors.forename: Richard H
authors.initials: RH
authors.lastname: Templer
authors.forename: John M
authors.initials: JM
authors.lastname: Seddon
mesh_terms: D002462:Cell Membrane / Q000737:chemistry* / Q000378:metabolism*; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry*; D011312:Pressure
chemical_list: D008055:Lipids