title: Imipenem-resistant Nocardia cyriacigeorgica infection in a child with chronic granulomatous disease.
abstract: Nocardia spp. can lead to local or disseminated infections, especially in immunocompromised patients. Combination therapy of amikacin and imipenem is commonly used to treat severe nocardial infections. We describe a patient with imipenem-resistant Nocardia cyriacigeorgica, which, to our knowledge, has not been previously reported among isolates of this species.
authors.affiliation: Department of Pediatrics, Children's Hospital of Geneva, University Hospital of Geneva, 6 Rue Willy-Donzé, 1211 Geneva, Switzerland.
authors.forename: Andrés
authors.initials: A
authors.lastname: Hagerman
authors.forename: Verónica
authors.initials: V
authors.lastname: Rodríguez-Nava
authors.forename: Patrick
authors.initials: P
authors.lastname: Boiron
authors.forename: Pierre-Alex
authors.initials: PA
authors.lastname: Crisinel
authors.forename: Klara M
authors.initials: KM
authors.lastname: Posfay-Barbe
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D024881:Drug Resistance, Bacterial; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D015378:Imipenem / Q000494:pharmacology*; D008297:Male; D008826:Microbial Sensitivity Tests; D009615:Nocardia / Q000187:drug effects* / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem