title: Effects of high dietary levels of Se-enriched yeast on tissues selenium content and meat quality traits - a model study in rats.
abstract: OBJECTIVE
  The aim of the trial was to evaluate effects of high dietary levels of Se-enriched yeast on selenium concentrations in muscle and liver tissue and on the meat quality traits in rats.
  
  
  METHODS
  The experimental feed mixtures were fed to Wistar Albino rats for a period of 10 weeks. They differed in the dose and in the form of Se supplement. Supplemental dose of 0.3 mg.kg-1 of Se per one kilogram of feed was used in group I (n = 10, sodium selenite) and in group II (n = 10, Se-enriched yeast). Elevated dose 2 mg.kg-1 Se per one kilogram of feed was used in group III (n = 10, sodium selenite) and in group IV (n = 10, Se-enriched yeast).
  
  
  RESULTS
  The use of elevated dietary Se level (2 mg.kg-1) in the form of sodium selenite did not increase lipid oxidation (malondialdehyde content) in muscles nor influenced meat quality traits. The use of elevated dietary Se level in the form of Se-enriched yeast resulted in higher Se muscle concentrations accompanied by increased of malondialdehyde content. The meat quality traits remained unaffected.
  
  
  CONCLUSIONS
  High selenium concentrations in muscle produced by Se-enriched yeast were accompanied by elevated MDA levels, but it did not negatively influence meat quality traits.
authors.affiliation: Swine Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic. fajtz@vfu.cz
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Fajt
authors.forename: Helena
authors.initials: H
authors.lastname: Modra
authors.forename: Tomas
authors.initials: T
authors.lastname: Banoch
authors.forename: Jana
authors.initials: J
authors.lastname: Blahova
authors.forename: Alena
authors.initials: A
authors.lastname: Salakova
authors.forename: Iva
authors.initials: I
authors.lastname: Steinhauserova
authors.forename: Martin
authors.initials: M
authors.lastname: Svoboda
mesh_terms: D000821:Animal Feed; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008315:Malondialdehyde / Q000378:metabolism; D008460:Meat; D023421:Models, Animal; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012643:Selenium / Q000378:metabolism* / Q000494:pharmacology*; D015003:Yeasts
chemical_list: D008315:Malondialdehyde; D012643:Selenium