title: [Proteomic analysis of myocardial hypertrophy induced by left kidney artery coarctation in rats].
abstract: OBJECTIVE
  To identify the expression of proteins in cardiomyocytes in rats with left kidney artery coarctation.
  
  
  METHODS
  16 male SD rats were separated into 2 groups (n=8): 2 kidney 1 Clip group (2K1C) and sham operation group (SO). The postoperational 8th week, after examination by normal doppler and tissue doppler echocardiography, the extracted proteins from cardiomyocytes were isolated by two-dimensional gel electrophoresis with staining. The gel images were acquired by scanner and 2-DE analysis software. Different spots observed on two 2D gels were selected and identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS).
  
  
  RESULTS
  Overall, 21 protein spots showed significant difference, and 14 out of which were identified.
  
  
  CONCLUSIONS
  Kidney artery coactation-induced cardiac hypertrophy displays different expression of proteins in cardiomyocytes.
authors.affiliation: Department of Kinesiology, Nanjing Sport Institute, Nanjing 210014, China. qi-huang006@foxmail.com
authors.forename: Yuan-yuan
authors.initials: YY
authors.lastname: Lv
authors.forename: Biao
authors.initials: B
authors.lastname: Sun
authors.forename: Ji-zheng
authors.initials: JZ
authors.lastname: Ma
mesh_terms: D000818:Animals; D006332:Cardiomegaly / Q000209:etiology / Q000378:metabolism*; D003250:Constriction; D008297:Male; D020543:Proteome / Q000032:analysis* / Q000378:metabolism; D040901:Proteomics / Q000379:methods; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012077:Renal Artery / Q000503:physiopathology*
chemical_list: D020543:Proteome