title: Preventive effect of fluoridated orthodontic resins subjected to high cariogenic challenges.
abstract: The aim of the present study was to evaluate the in vitro caries preventive effect of fluoridated orthodontic resins under pH cycling with two types of acid demineralizing saliva. Brackets were bonded to 60 bovine incisors, using either Transbond Plus Color Change (n=30) or Orthodontic Fill Magic (n=30) orthodontic resins. Each group of resin was divided into 3 subgroups (n=10): immersion in remineralizing artificial saliva for 14 days, pH cycling with high cariogenic challenge in acid saliva with pH 5.5, and acid saliva with pH 4.5. After 14 days of pH cycling, the caries preventive effect on the development of white spot lesion was evaluated considering the presence of inhibition zones to white spot lesions using two scores: 0= absence and 1= presence. Kruskal Wallis and Mann-Whitney tests (a=0.05) were used. Formation of white spot lesions was observed only under pH cycling using acid saliva with pH 4.5; with Transbond Plus Color Change being significantly more effective (p<0.05) in preventing the appearance of white spot lesions effect than Orthodontic Fill Magic. The acidity of the demineralizing solution influenced the formation of white spot lesions around orthodontic brackets under highly cariogenic conditions. Transbond Plus Color Change resin presented higher caries preventive effect than Orthodontic Fill Magic.
authors.affiliation: Department of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, RJ, Brazil.
authors.forename: Paula
authors.initials: P
authors.lastname: Passalini
authors.forename: Tatiana Kelly da Silva
authors.initials: TK
authors.lastname: Fidalgo
authors.forename: Erika Machado
authors.initials: EM
authors.lastname: Caldeira
authors.forename: Rogerio
authors.initials: R
authors.lastname: Gleiser
authors.forename: Matilde da Cunha Gonçalves
authors.initials: Mda C
authors.lastname: Nojima
authors.forename: Lucianne Cople
authors.initials: LC
authors.lastname: Maia
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D000818:Animals; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000737:chemistry; D002417:Cattle; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding / Q000379:methods; D003731:Dental Caries / Q000517:prevention & control*; D003738:Dental Cements / Q000737:chemistry; D003743:Dental Enamel / Q000187:drug effects*; D004037:Diet, Cariogenic; D005460:Fluorides, Topical / Q000008:administration & dosage* / Q000737:chemistry; D016910:Orthodontic Brackets; D019279:Resin Cements / Q000737:chemistry; D012464:Saliva, Artificial / Q000009:adverse effects; D018709:Statistics, Nonparametric; D017001:Tooth Demineralization / Q000517:prevention & control*
chemical_list: D000180:Acrylic Resins; D002327:Cariostatic Agents; D003188:Composite Resins; D003738:Dental Cements; C481898:Fill Magic; D005460:Fluorides, Topical; D019279:Resin Cements; D012464:Saliva, Artificial; C065742:Transbond; D017438:Bisphenol A-Glycidyl Methacrylate