title: Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases in Spain: microbiological and clinical features.
abstract: Extended-spectrum β-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 (5%) isolates, respectively, among 162 ESBL-producing Klebsiella pneumoniae (ESBL-Kp) strains obtained in a multicenter study in Spain. Predisposing factors for ESBL-Kp acquisition included invasive procedures, mechanical ventilation, and previous antimicrobial use.
authors.affiliation: Service of Microbiology, University Hospital Marqués de Valdecilla, Avda. Valdecilla s/n, 39008 Santander, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Ruiz de Alegría
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez-Baño
authors.forename: M E
authors.initials: ME
authors.lastname: Cano
authors.forename: J R
authors.initials: JR
authors.lastname: Hernández-Bello
authors.forename: J
authors.initials: J
authors.lastname: Calvo
authors.forename: E
authors.initials: E
authors.lastname: Román
authors.forename: M A
authors.initials: MA
authors.lastname: Díaz
authors.forename: A
authors.initials: A
authors.lastname: Pascual
authors.forename: L
authors.initials: L
authors.lastname: Martínez-Martínez
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006801:Humans; D007231:Infant, Newborn; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000473:pathology; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D013030:Spain / Q000453:epidemiology; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases