title: Identification of noncompliant glaucoma patients using Bayesian networks and the Eye-Drop Satisfaction Questionnaire.
abstract: OBJECTIVE
  To identify poorly compliant glaucoma patients, using the Eye-Drop Satisfaction Questionnaire (EDSQ).
  
  
  METHODS
  This was an observational cross-sectional study with compliance data collected by an electronic monitoring device. Patients with primary open-angle glaucoma or ocular hypertension completed the EDSQ, a six-dimension self-reported questionnaire addressing "treatment concern", "disease concern", "patient-clinician relationship", "positive beliefs", "treatment convenience", and "self-declared compliance". A Bayesian network (BN) was applied to explore compliance associations with EDSQ.
  
  
  RESULTS
  Among 169 patients who completed the EDSQ, 113 had valid Travalert® data, of whom 25 (22.1%) demonstrated low compliance. All six EDSQ dimensions were associated directly, or indirectly, with compliance. Two profiles exhibited low compliance, ie, patients aged younger than 77.5 years with a poor patient-physician relationship and self-declared poor compliance and patients aged older than 77.5 years with a poor patient-physician relationship and self-declared good compliance. The third profile showed high compliance, ie, patients aged younger than 77.5 years with a good patient-physician relationship and self-declared good compliance.
  
  
  CONCLUSIONS
  Our results confirm a central role for the patient-physician relationship in the compliance process. Age, self-declared compliance, and patient satisfaction with the patient-physician relationship are all dimensions worth exploring before glaucoma medication is switched or proceeding to laser treatment or surgery.
authors.affiliation: Hôpital des Quinzes-Vingt, Paris, France.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Nordmann
authors.forename: Christian
authors.initials: C
authors.lastname: Baudouin
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Renard
authors.forename: Philippe
authors.initials: P
authors.lastname: Denis
authors.forename: Antoine
authors.initials: A
authors.lastname: Regnault
authors.forename: Gilles
authors.initials: G
authors.lastname: Berdeaux