title: Letter: Localized cutaneous reaction to intramuscular vitamin K in a patient with acute fatty liver of pregnancy.
abstract: Vitamin K1 is frequently used in the treatment and prevention of hypoprothrombinemia and hemorrhagic disease of the newborn. It also serves as an antidote to anticoagulants. Erythematous, indurated, pruritic plaques uncommonly occur in adults after intramuscular injection with vitamin K1. We present a case of a localized cutaneous reaction to intramuscular vitamin K1 in a peripartum patient with acute fatty liver of pregnancy. The history and clinical presentation of our case is presented with a discussion of the pathogenesis pathogenesis of vitamin K1 and available treatment for this condition.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Sousa
authors.forename: Lindsey
authors.initials: L
authors.lastname: Hunter
authors.forename: Matthew
authors.initials: M
authors.lastname: Petitt
authors.forename: Michael George
authors.initials: MG
authors.lastname: Wilkerson
mesh_terms: D000208:Acute Disease; D003875:Drug Eruptions / Q000209:etiology*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004485:Eczema / Q000139:chemically induced; D004890:Erythema / Q000139:chemically induced; D005234:Fatty Liver / Q000150:complications*; D005260:Female; D006801:Humans; D007020:Hypoprothrombinemias / Q000188:drug therapy / Q000209:etiology; D007273:Injections, Intramuscular; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011644:Puerperal Disorders / Q000209:etiology*; D010837:Vitamin K 1 / Q000008:administration & dosage / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D010837:Vitamin K 1