title: [Lung transplantation for secondary interstitial pneumonitis caused by treatment for primary mediastinal diffuse large B-cell lymphoma].
abstract: A 34-year-old woman was diagnosed as primary mediastinal diffuse large B-cell lymphoma, treated by cyclophosphamide, doxorubicin, vincrisitne, prednisolone (CHOP) chemotherapy and radiation therapy, and received high-dose ranimustine, cytarabine, etoposide, cyclophosphamide (MCVAC) chemotherapy with autologous peripheral blood stem cell transplantation. Seven years after complete remission was achieved, she recognized dyspnea and was diagnosed secondary interstitial pneumonitis caused by chemotherapy and/or radiotherapy. Because her symptoms and pulmonary function got worsen gradually, she underwent lung transplantation from a brain death donor when she was 47-year-old. She has successfully rehabilitated and returned to her life without oxygen inhalation therapy.
authors.affiliation: Department of General Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Mitsutomo
authors.initials: M
authors.lastname: Kohno
authors.forename: Naoki
authors.initials: N
authors.lastname: Hasegawa
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Okamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Kondo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nomori
mesh_terms: D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000209:etiology* / Q000601:surgery*; D016040:Lung Transplantation; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000628:therapy*; D008875:Middle Aged