title: N-(3-Oxo-1-thia-4-aza-spiro-[4.5]dec-4-yl)-6-phenyl-imidazo[2,1-b][1,3]thia-zole-3-acetamide hemihydrate.
abstract: The title compound, C(21)H(22)N(4)O(2)S(2)·0.5H(2)O, crystallizes with two mol-ecules in the asymmetric unit. The dihedral angles between the phenyl and imidazothiazole ring systems are 19.16 (9) and 21.37 (9)°. In the imidazothiazole ring systems, the cyclohexane rings adopt chair conformations, while the thiazole rings have distorted envelope conformations. The two mol-ecules are stabilized by intra-molecular N-H⋯O, O-H⋯O and C-H⋯S inter-actions and the crystal structure is stabilized by inter-molecular N-H⋯O, O-H⋯O, C-H⋯O and C-H⋯N inter-actions.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Akkurt
authors.forename: Serife Pınar
authors.initials: SP
authors.lastname: Yalçın
authors.forename: Nuray Ulusoy
authors.initials: NU
authors.lastname: Güzeldemirci
authors.forename: Orhan
authors.initials: O
authors.lastname: Büyükgüngör