title: Traumatic dissection of a coronary artery: detection by multislice computed tomography and use of tirofiban as a reversible platelet inhibitor.
abstract: We report on a trauma victim without history of or risk factors for cardiac disease, who suffered coronary artery dissection caused by blunt chest injury (BCI). Myocardial ischaemia was detected by multislice computed tomography (MSCT) promptly after trauma centre admission and managed by immediate revascularisation. Thoracic trauma may cause myocardial ischaemia in the absence of a specific risk profile. MSCT, as part of initial work-up in severely injured patients, may support differential diagnosis after BCI. Tirofiban and unfractionated heparin as short-acting anticoagulants warrant stent patency and concurrently offer the possibility of quick recovery of haemostasis in case of haemorrhage.
authors.affiliation: Department of Surgery, University Hospital of Ludwig-Maximilians-University, Downtown Campus, Munich, Germany. lney@med.lmu.de
authors.forename: Ludwig
authors.initials: L
authors.lastname: Ney
authors.forename: Markus
authors.initials: M
authors.lastname: Körner
authors.forename: Marcus
authors.initials: M
authors.lastname: Leibig
authors.forename: Bernhard
authors.initials: B
authors.lastname: Heindl
mesh_terms: D000063:Accidents, Traffic; D000784:Aortic Dissection / Q000000981:diagnostic imaging* / Q000209:etiology; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging* / Q000209:etiology; D017023:Coronary Angiography / Q000379:methods*; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000188:drug therapy / Q000209:etiology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013898:Thoracic Injuries / Q000150:complications; D000077466:Tirofiban; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D010975:Platelet Aggregation Inhibitors; D014443:Tyrosine; D000077466:Tirofiban