title: [The dissemination of CMV in urine of different group from Guangxi and the relationship between CMV infection and renal disease].
abstract: OBJECTIVE
  To detect Human Cytomegalovirus (HCMV) DNA in urine samples from the following groups: pregnant women, sick newborns, hospitalized nephropathy patients, renal transplant recipients and normal population. Preliminarily study the relationship of HCMV infection and renal disease.
  
  
  METHODS
  To detect HCMV DNA in morning urine samples by Real-time fluorescence quantitative PCR (FQ-PCR).
  
  
  RESULTS
  The positive rates of HCMV DNA in the urine of pregnant women,sick newborns, hospitalized nephropathy patients, renal transplant recipients and normal population are 8.18%, 3.45%, 18.54%, 25.42%, 0.56%.
  
  
  CONCLUSIONS
  The infection rates of HCMV in the urine of pregnant women and sick newborns are very high in Guangxi, it should take serious measures to prevent and control the situation. HCMV probably participate in the injury of kidney, and worsen the disease. It should be one of the causes of renal disease.
authors.affiliation: School of Pubic Health, Guangxi Medical University, Nanning 530021 ,China.
authors.forename: Zhi-ping
authors.initials: ZP
authors.lastname: Chen
authors.forename: Hao-bin
authors.initials: HB
authors.lastname: Cai
authors.forename: Yu
authors.initials: Y
authors.lastname: He
authors.forename: Shan
authors.initials: S
authors.lastname: Li
authors.forename: Li-lan
authors.initials: LL
authors.lastname: Wang
authors.forename: Xiao-xia
authors.initials: XX
authors.lastname: Lao
authors.forename: Tai-jie
authors.initials: TJ
authors.lastname: Li
authors.forename: Chun-hui
authors.initials: CH
authors.lastname: Hu
authors.forename: Yan
authors.initials: Y
authors.lastname: Deng
authors.forename: Jin-yao
authors.initials: JY
authors.lastname: Qin
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Yan-hua
authors.initials: YH
authors.lastname: Yang
mesh_terms: D002681:China; D003587:Cytomegalovirus / Q000472:pathogenicity* / Q000502:physiology; D003586:Cytomegalovirus Infections / Q000150:complications / Q000453:epidemiology* / Q000635:transmission*; D004279:DNA, Viral / Q000032:analysis; D005006:Ethnicity; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000150:complications / Q000453:epidemiology*; D016030:Kidney Transplantation; D008727:Methotrexate / Q000494:pharmacology; D016133:Polymerase Chain Reaction; D011247:Pregnancy
chemical_list: D004279:DNA, Viral; D008727:Methotrexate