title: Fabrication of glucose fiber sensor based on immobilized GOD technique for rapid measurement.
abstract: The concentration and pH value of the immobilized glucose oxidase (GOD) are critical parameters in a glucose sensor. In this study, we develop a glucose fiber sensor integrated with heterodyne interferometry to measure the phase difference arising from the chemical reaction between glucose and GOD. Our studies show that the response time and resolution of this sensor will be strongly affected by the pH and concentration properties of GOD. In addition, the results show good linearity between the calibration curve for the glucose solution and serum based sample. The response time of this sensor can be shorter than 3 seconds and best resolutions are 0.1 and 0.136 mg/dl for glucose solution and serum based sample, respectively.
authors.affiliation: Department of Photonics Engineering, Yuan Ze University, Chung-Li, Taiwan.
authors.forename: Ting-Qian
authors.initials: TQ
authors.lastname: Lin
authors.forename: Yin-Lin
authors.initials: YL
authors.lastname: Lu
authors.forename: Cheng-Chih
authors.initials: CC
authors.lastname: Hsu
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D005949:Glucose Oxidase / Q000737:chemistry*; D007368:Interferometry / Q000295:instrumentation*; D018511:Systems Integration
chemical_list: D005949:Glucose Oxidase; D005947:Glucose