title: Different spontaneous pulmonary metastasis inhibitions against lewis lung carcinoma in mice by bisdioxopiperazine compounds of different treatment schedules.
abstract: Spontaneous neoplasm metastasis, a fatalist pathological feature of cancer, is a long-evolving, multi-steps process that can now only be treated or controlled by drugs or immuno-modulators. As we have previously hypothesized, each drug or immuno-modulator might act differently within various stages of a metastasis. Therefore any researches helping to determine these differences will be beneficial for updating therapeutics for metastasis. In this work, we have testified this hypothesis by using a series of well-known anti-metastatic agents â Bisdioxopiperazine compounds.
authors.affiliation: Shanghai University, Shanghai 200444, PR China. ludayong@sh163.net
authors.forename: Da-Yong
authors.initials: DY
authors.lastname: Lu
authors.forename: Fu-Geng
authors.initials: FG
authors.lastname: Wu
authors.forename: Zu-Ming
authors.initials: ZM
authors.lastname: Zhen
authors.forename: Ting-Ren
authors.initials: TR
authors.lastname: Lu
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Wu
authors.forename: Jin-Yu
authors.initials: JY
authors.lastname: Che
authors.forename: Bin
authors.initials: B
authors.lastname: Xu