title: Complete genome sequence of the metabolically versatile plant growth-promoting endophyte Variovorax paradoxus S110.
abstract: Variovorax paradoxus is a microorganism of special interest due to its diverse metabolic capabilities, including the biodegradation of both biogenic compounds and anthropogenic contaminants. V. paradoxus also engages in mutually beneficial interactions with both bacteria and plants. The complete genome sequence of V. paradoxus S110 is composed of 6,754,997 bp with 6,279 predicted protein-coding sequences within two circular chromosomes. Genomic analysis has revealed multiple metabolic features for autotrophic and heterotrophic lifestyles. These metabolic diversities enable independent survival, as well as a symbiotic lifestyle. Consequently, S110 appears to have evolved into a superbly adaptable microorganism that is able to survive in ever-changing environmental conditions. Based on our findings, we suggest V. paradoxus S110 as a potential candidate for agrobiotechnological applications, such as biofertilizer and biopesticide. Because it has many associations with other biota, it is also suited to serve as an additional model system for studies of microbe-plant and microbe-microbe interactions.
authors.affiliation: Department of Civil and Environmental Engineering, KAIST, Republic of Korea. jihan@kaist.ac.kr
authors.forename: Jong-In
authors.initials: JI
authors.lastname: Han
authors.forename: Hong-Kyu
authors.initials: HK
authors.lastname: Choi
authors.forename: Seung-Won
authors.initials: SW
authors.lastname: Lee
authors.forename: Paul M
authors.initials: PM
authors.lastname: Orwin
authors.forename: Jina
authors.initials: J
authors.lastname: Kim
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Laroe
authors.forename: Tae-Gyu
authors.initials: TG
authors.lastname: Kim
authors.forename: Jennifer
authors.initials: J
authors.lastname: O'Neil
authors.forename: Jared R
authors.initials: JR
authors.lastname: Leadbetter
authors.forename: Sang Yup
authors.initials: SY
authors.lastname: Lee
authors.forename: Cheol-Goo
authors.initials: CG
authors.lastname: Hur
authors.forename: Jim C
authors.initials: JC
authors.lastname: Spain
authors.forename: Galina
authors.initials: G
authors.lastname: Ovchinnikova
authors.forename: Lynne
authors.initials: L
authors.lastname: Goodwin
authors.forename: Cliff
authors.initials: C
authors.lastname: Han
mesh_terms: D002876:Chromosomes, Bacterial; D016680:Genome, Bacterial; D008670:Metals / Q000633:toxicity; D008969:Molecular Sequence Data; D010944:Plants / Q000382:microbiology; D020560:Proteobacteria / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D013559:Symbiosis / Q000235:genetics
chemical_list: D008670:Metals