title: Highly enantioselective nitrone cycloadditions with 2-alkenoyl pyridine N-oxides catalyzed by Cu(II)-BOX complexes.
abstract: Enantioselective nitrone cycloadditions with 2-alkenoyl pyridine N-oxides as dipolarophiles have been reported. The reaction is catalyzed by Cu(II)-BOX complexes to give the expected isoxazolidine products with high diastereo- and enantioselectivity.
authors.affiliation: Departament de Química Orgànica, Facultat de Química, Universitat de València, C/Dr. Moliner, 50, E-46100 Burjassot, València, Spain.
authors.forename: Santiago
authors.initials: S
authors.lastname: Barroso
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Blay
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Muñoz
authors.forename: José R
authors.initials: JR
authors.lastname: Pedro
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009589:Nitrogen Oxides / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D007555:Isoxazoles; D009589:Nitrogen Oxides; D009942:Organometallic Compounds; D011725:Pyridines; C015388:nitrones; D003300:Copper; C013229:pyridine N-oxide