title: Intracarotid amobarbital procedure for epilepsy surgery.
abstract: The intracarotid amobarbital procedure (IAP) has been used for more than half a century to determine language dominance and to assess risk for amnesia after anterior temporal lobectomy. However, because of the risk associated with angiography and the development of noninvasive techniques, the need for the IAP when evaluating patients for epilepsy surgery can now be questioned. The purpose of this review is to examine the clinical indications and efficacy of the Wada test in the preoperative evaluation of epilepsy surgery candidates. This article summarizes a debate that took place during the 2009 American Epilepsy Society (AES) annual course.
authors.affiliation: Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: Ashwini
authors.initials: A
authors.lastname: Sharan
authors.forename: Yinn Cher
authors.initials: YC
authors.lastname: Ooi
authors.forename: John
authors.initials: J
authors.lastname: Langfitt
authors.forename: Michael R
authors.initials: MR
authors.lastname: Sperling
mesh_terms: D000647:Amnesia / Q000175:diagnosis; D000654:Amobarbital; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology* / Q000601:surgery*; D007839:Functional Laterality / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives; D007802:Language; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications / Q000175:diagnosis*; D011237:Predictive Value of Tests
chemical_list: D006993:Hypnotics and Sedatives; D000654:Amobarbital