title: SUMOylation and bacterial pathogens.
abstract: During infection, bacterial pathogens interfere with many different post-translational modifications of the host cell to promote their own survival and replication. By stimulating or counteracting host post-translational modifications, these pathogens may control locally and specifically the fate and function of host factors critical for the infection process. Besides phosphorylation or ubiquitylation, for which many examples of modulation by pathogens exist, a post-translational modification called SUMOylation was recently shown to be targeted by pathogenic bacteria.
authors.affiliation: Unité des Interactions Bactéries-Cellules, Département de Biologie Cellulaire et Infection, Institut Pasteur, Paris, France.
authors.forename: David
authors.initials: D
authors.lastname: Ribet
authors.forename: Pascale
authors.initials: P
authors.lastname: Cossart
mesh_terms: D001419:Bacteria / Q000378:metabolism* / Q000472:pathogenicity*; D001426:Bacterial Proteins / Q000378:metabolism*; D006801:Humans; D008089:Listeria monocytogenes / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D025841:Small Ubiquitin-Related Modifier Proteins / Q000378:metabolism*; D058207:Sumoylation; D044763:Ubiquitin-Conjugating Enzymes / Q000378:metabolism; D037521:Virulence Factors / Q000378:metabolism*; D016959:Xanthomonas campestris / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity
chemical_list: D001426:Bacterial Proteins; D025841:Small Ubiquitin-Related Modifier Proteins; D037521:Virulence Factors; D044763:Ubiquitin-Conjugating Enzymes