title: Effects of omega-3 polyunsaturated fatty acids on cardiac myocyte protection.
abstract: Many epidemiologic, observational and randomized human clinical trials have demonstrated beyond doubt the protective cardiovascular effects of omega-3 polyunsaturated fatty acids (PUFAs). Cardiac myocytes protection by omega-3 PUFAs involves several mechanisms which might have a synergistic effect. This review provides a summary of the in vitro and in vivo effects of omega-3 PUFAs on cardiac myocytes health and reports the outcome of a number of clinical trials in patients consuming omega-3 PUFAs.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences, University of Rome, Tor Vergata, Rome, Italy. bei@med.uniroma2.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Bei
authors.forename: Alessandro
authors.initials: A
authors.lastname: Frigiola
authors.forename: Laura
authors.initials: L
authors.lastname: Masuelli
authors.forename: Laura
authors.initials: L
authors.lastname: Marzocchella
authors.forename: Ilaria
authors.initials: I
authors.lastname: Tresoldi
authors.forename: Andrea
authors.initials: A
authors.lastname: Modesti
authors.forename: Fabio
authors.initials: F
authors.lastname: Galvano
mesh_terms: D000818:Animals; D002316:Cardiotonic Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006801:Humans; D032383:Myocytes, Cardiac / Q000187:drug effects*; D015222:Sodium Channels / Q000187:drug effects
chemical_list: D002316:Cardiotonic Agents; D015525:Fatty Acids, Omega-3; D015222:Sodium Channels