title: Introduction to focus issue: dynamics in systems biology.
abstract: The methods of nonlinear systems form an extensive toolbox for the study of biology, and systems biology provides a rich source of motivation for the development of new mathematical techniques and the furthering of understanding of dynamical systems. This Focus Issue collects together a large variety of work which highlights the complementary nature of these two fields, showing what each has to offer the other. While a wide range of subjects is covered, the papers often have common themes such as "rhythms and oscillations," "networks and graph theory," and "switches and decision making." There is a particular emphasis on the links between experimental data and modeling and mathematical analysis.
authors.affiliation: Institute for Complex Systems and Mathematical Biology, SUPA King's College, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom. c.a.brackley@abdn.ac.uk
authors.forename: Chris A
authors.initials: CA
authors.lastname: Brackley
authors.forename: Oliver
authors.initials: O
authors.lastname: Ebenhöh
authors.forename: Celso
authors.initials: C
authors.lastname: Grebogi
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kurths
authors.forename: Alessandro
authors.initials: A
authors.lastname: de Moura
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Romano
authors.forename: Marco
authors.initials: M
authors.lastname: Thiel
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002453:Cell Cycle; D006801:Humans; D053858:Metabolic Networks and Pathways; D008954:Models, Biological; D017711:Nonlinear Dynamics; D049490:Systems Biology