title: 6-Cyclo-hexyl-methyl-2-cyclo-hexyl-sul-fanyl-5-isopropyl-pyrimidin-4(3H)-one.
abstract: The title compound, C(20)H(32)N(2)OS, was obtained during the course of our investigation on 2-alkylsulfanyl-6-benzyl-3,4-dihydropyrimidin-4(3H)-ones (S-DABOs) showing favourable anti-HIV-1 activity. Both cyclo-hexane rings adopt chair conformations. The angle at the methyl-ene C atom linking the pyrimidine and cyclo-hexane ring is 113.7 (3)°, which is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibitors. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into dimers and stabilize the crystal structure of the compound. In addition, an intra-molecular C-H⋯O hydrogen bond is observed.
authors.forename: Chun-Sheng
authors.initials: CS
authors.lastname: Zhang
authors.forename: Da-Xiong
authors.initials: DX
authors.lastname: Li
authors.forename: De-Hua
authors.initials: DH
authors.lastname: Zhang
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: He
authors.forename: Cong
authors.initials: C
authors.lastname: Li