title: [Memory disorders in multiple sclerosis].
abstract: Disturbances of short-term memory are the most early and frequent alterations of cognitive functions in multiple sclerosis (MS). We have conducted a complex neuropsychological and brain MRI study in patients with MS. The disturbances of memory were found in MS patients regardless of disease type and duration. The central pathophysiological process of the development of cognitive disturbances in MS is the lesion of projection, commissural and long association fibers that results in the disturbances of integrative brain activity and activation of the cortex in deep structures, first of all, in the thalamus.
authors.forename: K S
authors.initials: KS
authors.lastname: Meshkova
authors.forename: I V
authors.initials: IV
authors.lastname: Damulin
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology*; D008570:Memory, Short-Term; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology*; D009483:Neuropsychological Tests; D055815:Young Adult