title: Effects of combined aerobic and resistance exercise training in adults with and without Down syndrome.
abstract: OBJECTIVE
  To determine whether adults with Down syndrome (DS) could improve their submaximal and peak exercise capacity, as for adults without disabilities, after 12 weeks of combined (aerobic and resistance) exercise training.
  
  
  METHODS
  Prospective study comparing the effects of a 12-week combined exercise program on submaximal and peak exercise capacity of adults with and without DS.
  
  
  METHODS
  University facilities.
  
  
  METHODS
  Participants with DS (n=13; mean ± SD age, 36.5±5.5y) and participants without disabilities (n=12; mean age, 38.7±8.3y).
  
  
  METHODS
  Combined exercise training for 12 weeks. Endurance training was performed 3 days a week for 30 minutes at 65% to 85% of peak oxygen consumption (Vo₂peak). Resistance training was prescribed for 2 days a week and consisted of 2 rotations in a circuit of 9 exercises at 12-repetition maximum.
  
  
  METHODS
  Submaximal and maximal graded exercise tests with metabolic and heart rate measurements. Walking economy and Vo₂peak were considered the main outcomes.
  
  
  RESULTS
  Participants with DS and those without disabilities showed similar values for body mass index and relative fat mass at pre- and posttraining periods. Walking economy and Vo₂peak overall were lower in participants with DS than participants without disabilities (P<.05). Training improved walking economy and Vo₂peak in participants with DS and those without disabilities (P<.05); additionally, the magnitude of changes induced by training was similar between groups.
  
  
  CONCLUSIONS
  Overall, a 12-week combined exercise regimen induced gains of similar magnitude between adults with and without DS for submaximal and peak exercise capacity.
authors.affiliation: Center of Human Performance, Technical University of Lisbon, Portugal. gvmendonca@gmail.com
authors.forename: Goncalo V
authors.initials: GV
authors.lastname: Mendonca
authors.forename: Fernando D
authors.initials: FD
authors.lastname: Pereira
authors.forename: Bo
authors.initials: B
authors.lastname: Fernhall
mesh_terms: D000328:Adult; D015992:Body Mass Index; D004314:Down Syndrome / Q000534:rehabilitation*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D011446:Prospective Studies; D055070:Resistance Training / Q000379:methods; D013997:Time Factors