title: [Effect of taurine on thyroid hormone and second messenger in myocardium of rats after exhaustive exercise].
abstract: OBJECTIVE
  Probe into protective action of taurine against exercise-induced myocardial damage in rats after exhaustive exercise.
  
  
  METHODS
  Using the model of exhaustive exercise, the present study researches into effects of taurine on the content of triiodothyronine (T3) and tetraiodothyronine (T4) in serum and myocardium as well as the activity of T(4) 5' deiodinase (T(4)5'-DI) and second messenger cAMP in myocardium of rats.
  
  
  RESULTS
  The content of T3 in serum and myocardium, T(4)5'-DI activity, second messenger cAMP in myocardium increased significantly (P < 0.01) while that of T4 in serum and myocardium did not change significantly after exhaustive swimming. The supplement of taurine might significantly inhibit above changes caused by exhaustive exercise.
  
  
  CONCLUSIONS
  Taurine could protect myocardium from exhaustive exercise induced damage by inhibiting hypermetabolism of thyroid hormone and change of second messenger.
authors.affiliation: College of Physical Education, Yangzhou University, Yangzhou 225002, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Shu-Huai
authors.initials: SH
authors.lastname: Huang
authors.forename: Bing-Meng
authors.initials: BM
authors.lastname: Chen
mesh_terms: D000818:Animals; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D051381:Rats; D017207:Rats, Sprague-Dawley; D015290:Second Messenger Systems / Q000187:drug effects*; D013654:Taurine / Q000494:pharmacology*; D013963:Thyroid Hormones / Q000097:blood*
chemical_list: D013963:Thyroid Hormones; D013654:Taurine