title: Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009).
abstract: Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report.
authors.affiliation: The Tisch Cancer Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. paolo.boffetta@i-pri.org
authors.forename: Paolo
authors.initials: P
authors.lastname: Boffetta
authors.forename: Graham A
authors.initials: GA
authors.lastname: Colditz
authors.forename: John D
authors.initials: JD
authors.lastname: Potter
authors.forename: Laurence
authors.initials: L
authors.lastname: Kolonel
authors.forename: Paula J
authors.initials: PJ
authors.lastname: Robson
authors.forename: Reza
authors.initials: R
authors.lastname: Malekzadeh
authors.forename: Daniela
authors.initials: D
authors.lastname: Seminara
authors.forename: Ellen L
authors.initials: EL
authors.lastname: Goode
authors.forename: Keun-Young
authors.initials: KY
authors.lastname: Yoo
authors.forename: Paul
authors.initials: P
authors.lastname: Demers
authors.forename: Richard
authors.initials: R
authors.lastname: Gallagher
authors.forename: Ross
authors.initials: R
authors.lastname: Prentice
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yasui
authors.forename: Kieran
authors.initials: K
authors.lastname: O'Doherty
authors.forename: Gloria M
authors.initials: GM
authors.lastname: Petersen
authors.forename: Cornelia M
authors.initials: CM
authors.lastname: Ulrich
authors.forename: Ilona
authors.initials: I
authors.lastname: Csizmadi
authors.forename: Ernest K
authors.initials: EK
authors.lastname: Amankwah
authors.forename: Nigel T
authors.initials: NT
authors.lastname: Brockton
authors.forename: Karen
authors.initials: K
authors.lastname: Kopciuk
authors.forename: S Elizabeth
authors.initials: SE
authors.lastname: McGregor
authors.forename: Linda E
authors.initials: LE
authors.lastname: Kelemen
mesh_terms: D002170:Canada; D016022:Case-Control Studies; D002986:Clinical Trials as Topic / Q000379:methods; D015331:Cohort Studies; D004781:Environmental Exposure / Q000032:analysis; D006801:Humans; D058028:Research Report; D018570:Risk Assessment / Q000379:methods; D018401:Sample Size