title: Prostate size is not associated with recovery of sexual function after minimally invasive radical prostatectomy.
abstract: OBJECTIVE
  To investigate the association of prostate weight with recovery of sexual function after minimally invasive radical prostatectomy.
  
  
  METHODS
  Between April 2001 and September 2007, two surgeons performed 856 consecutive laparoscopic radical prostatectomies for clinically localized prostate cancer. Patients were stratified into three groups by prostate weight: <35 g, 35-70 g, and >70 g. Sexual and urinary outcomes were assessed prospectively using the Expanded Prostate Cancer Index Composite (EPIC) questionnaire. Patients who underwent nerve sparing (unilateral or bilateral) with complete preoperative EPIC data, a minimum preoperative Sexual Health Inventory for Men score ≥21, and a minimum of 3 months of complete postoperative EPIC data were included in the analysis.
  
  
  RESULTS
  Of the cohort of 856 men, 324 (38%) had complete, evaluable data and met the inclusion criteria for this study. Preoperatively, there were no significant differences by prostate weight in the EPIC sexual function or bother subscale scores or the proportion of patients participating in sexual intercourse. Postoperatively, we observed statistically similar returns to baseline EPIC sexual function and bother subscale scores and participation in sexual intercourse across all gland weight groups at all time points. EPIC sexual domain scores and the proportions of patients participating in sexual intercourse continued to increase up to 24 months postoperatively, but no group returned to preoperative function at any sampling point.
  
  
  CONCLUSIONS
  Prostate size is not associated with postoperative recovery of sexual function in men undergoing minimally invasive radical prostatectomy.
authors.affiliation: Division of Urologic Oncology, Moores Comprehensive Cancer Center, University of California, San Diego, La Jolla, CA 92103-8897, USA.
authors.forename: Nicholas T
authors.initials: NT
authors.lastname: Ward
authors.forename: J Kellogg
authors.initials: JK
authors.lastname: Parsons
authors.forename: Adam W
authors.initials: AW
authors.lastname: Levinson
authors.forename: Herman S
authors.initials: HS
authors.lastname: Bagga
authors.forename: Lynda Z
authors.initials: LZ
authors.lastname: Mettee
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Su
authors.forename: Christian P
authors.initials: CP
authors.lastname: Pavlovich
mesh_terms: D003075:Coitus / Q000502:physiology; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D010410:Penile Erection; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy / Q000379:methods*; D011788:Quality of Life; D020127:Recovery of Function / Q000502:physiology; D011795:Surveys and Questionnaires