title: Successful, combined long-term treatment of cerebral aspergillosis in a liver transplant patient.
abstract: Invasive aspergillosis has long been recognized as one of the most significant and often fatal opportunistic fungal infections in liver transplant recipients. We report a case of a liver transplant recipient who developed an Aspergillus fumigatus brain abscess that produced significant neurologic symptoms. The patient was managed successfully with a combination of surgery and medical treatment with Voriconazole. To our knowledge, this is the second such case reported in the literature.
authors.forename: Parmenion P
authors.initials: PP
authors.lastname: Tsitsopoulos
authors.forename: Georgios
authors.initials: G
authors.lastname: Tsoulfas
authors.forename: Christos
authors.initials: C
authors.lastname: Tsonidis
authors.forename: George
authors.initials: G
authors.lastname: Imvrios
authors.forename: Vasilios
authors.initials: V
authors.lastname: Papanikolaou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Giakoustidis
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Marinopoulos
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Takoudas
authors.forename: Phillipos D
authors.initials: PD
authors.lastname: Tsitsopoulos
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D001232:Aspergillus fumigatus / Q000187:drug effects / Q000302:isolation & purification*; D001922:Brain Abscess / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D004322:Drainage; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016031:Liver Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D020953:Neuroaspergillosis / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery*; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D011743:Pyrimidines / Q000008:administration & dosage; D014180:Transplantation; D014230:Triazoles / Q000008:administration & dosage; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole