title: Sclerosing mucoepidermoid carcinoma of the salivary gland: Case report and literature review.
abstract: Sclerosing mucoepidermoid carcinoma (SMEC) is an extremely rare variant of mucoepidermoid carcinoma with unique histologic features. To the best of our knowledge, only 14 cases of salivary gland SMEC have been previously reported in the English-language literature since it was discovered in 1987. We report a new case of salivary gland SMEC, and we review the literature. Because of SMEC's distinctive histologic features and rarity, its diagnosis can be difficult. Moreover, no clear treatment strategy has emerged with regard to adjuvant postoperative radiotherapy. We attempt to elucidate a natural course of this disease, and we propose a conservative approach to postoperative management.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Montreal General Hospital, McGill University, 1650 Cedar Ave., Suite A2-141, Montreal, QC H3G 1A4, Canada.
authors.forename: Asher A
authors.initials: AA
authors.lastname: Mendelson
authors.forename: Khalil
authors.initials: K
authors.lastname: al-Macki
authors.forename: Peter
authors.initials: P
authors.lastname: Chauvin
authors.forename: Karen M
authors.initials: KM
authors.lastname: Kost
mesh_terms: D044963:Biopsy, Fine-Needle; D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005629:Frozen Sections / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry; D037981:Neck Dissection / Q000379:methods; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D035583:Rare Diseases; D012086:Reoperation / Q000379:methods; D018570:Risk Assessment; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D012598:Sclerosis / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult