title: A novel Zn-catalyzed hydroamination of propargylamides: a general synthesis of di- and tri-substituted imidazoles.
abstract: Starting from commercially available amines and propargylamides a variety of substituted imidazoles were synthesized via a novel hydroamination-cyclization sequence. The target compounds are obtained in good to excellent yields in the presence of catalytic amounts of zinc triflate.
authors.affiliation: Leibniz-Institut für Katalyse an der Universität Rostock e.V., Albert-Einstein-Str. 29a, D-18059 Rostock, Germany.
authors.forename: Anahit
authors.initials: A
authors.lastname: Pews-Davtyan
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
mesh_terms: D000577:Amides / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D007093:Imidazoles; D008698:Mesylates; C012077:trifluoromethanesulfonic acid