title: Combined technique for the correction of lower-limb deformities resulting from metabolic bone disease.
abstract: We present the results of the surgical correction of lower-limb deformities caused by metabolic bone disease. Our series consisted of 17 patients with a diagnosis of hypophosphataemic rickets and two with renal osteodystrophy; their mean age was 25.6 years (14 to 57). In all, 43 lower-limb segments (27 femora and 16 tibiae) were osteotomised and the deformity corrected using a monolateral external fixator. The segment was then stabilised with locked intramedullary nailing. In addition, six femora in three patients were subsequently lengthened by distraction osteogenesis. The mean follow-up was 60 months (18 to 120). The frontal alignment parameters (the mechanical axis deviation, the lateral distal femoral angle and the medial proximal tibial angle) and the sagittal alignment parameters (the posterior distal femoral angle and the posterior proximal tibial angle) improved post-operatively. The external fixator was removed either at the end of surgery or at the end of the lengthening period, allowing for early mobilisation and weight-bearing. We encountered five problems and four obstacles in the programme of treatment. The use of intramedullary nails prevented recurrence of deformity and refracture.
authors.affiliation: Istanbul University, Istanbul Medical School, Capa, Istanbul, 34390, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Kocaoglu
authors.forename: F E
authors.initials: FE
authors.lastname: Bilen
authors.forename: C
authors.initials: C
authors.lastname: Sen
authors.forename: L
authors.initials: L
authors.lastname: Eralp
authors.forename: H I
authors.initials: HI
authors.lastname: Balci
mesh_terms: D000293:Adolescent; D000328:Adult; D001858:Bone Nails; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000000981:diagnostic imaging / Q000601:surgery*; D016267:External Fixators; D053098:Familial Hypophosphatemic Rickets / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D035002:Lower Extremity / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019857:Osteogenesis, Distraction / Q000379:methods; D010027:Osteotomy / Q000379:methods; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery; D055815:Young Adult