title: C. elegans star proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development.
abstract: A comprehensive understanding of the C. elegans STAR proteins GLD-1 and ASD-2 is emerging from a combination of studies. Those employing genetic analysis reveal in vivo function, others involving biochemical approaches pursue the identification of mRNA targets through which these proteins act. Lastly, mechanistic studies provide the molecular pathway of target mRNA regulation.
authors.affiliation: Department of Biological Sciences, University at Albany, SUNY, Albany, New York 12222, USA. mhlee@albany.edu
authors.forename: Min-Ho
authors.initials: MH
authors.lastname: Lee
authors.forename: Tim
authors.initials: T
authors.lastname: Schedl
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D018510:RNA, Helminth / Q000235:genetics / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: C551797:ASD-2 protein, C elegans; D029742:Caenorhabditis elegans Proteins; C094448:GLD-1 protein, C elegans; D018510:RNA, Helminth; D016601:RNA-Binding Proteins