title: A patient with foot ulcer and severe metabolic alkalosis.
abstract: We report a case of triple acid-base disorder with metabolic alkalosis as the primary disorder in a 65-year-old man due to ingestion and application to leg ulcers of baking soda (calcium bicarbonate). The blood pH was 7.65 with hypochloremia, hypokalemia, and prerenal azotemia. He was treated with isotonic saline with K replacement, and the patient improved without any adverse clinical consequences. We discuss the causes, mechanisms, and management of Cl-responsive (depletion) metabolic alkalosis.
authors.affiliation: Department of Medicine, Division of Nephrology & Hypertension, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA.
authors.forename: Ruby Samuel
authors.initials: RS
authors.lastname: John
authors.forename: Sonia
authors.initials: S
authors.lastname: Simoes
authors.forename: Alluru S
authors.initials: AS
authors.lastname: Reddi
mesh_terms: D000368:Aged; D000471:Alkalosis / Q000139:chemically induced* / Q000150:complications; D001639:Bicarbonates / Q000009:adverse effects / Q000627:therapeutic use; D004636:Emergency Service, Hospital; D016523:Foot Ulcer / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male
chemical_list: D001639:Bicarbonates; C031556:calcium bicarbonate