title: Membranoproliferative glomerulonephritis in a postpartum woman with sickle cell disease.
abstract: Renal insufficiency occurs in a considerable proportion of patients with sickle cell disease. Common advanced glomerular lesions include focal segmental glomerulosclerosis and nonimmune membranoproliferative glomerulonephritis. Due to the paucity of data supporting an immune-mediated pathophysiology, anti-inflammatory and immunosuppressive therapies have not been successfully evaluated in such patients. We present a case of membranoproliferative glomerulonephritis in a postpartum patient with sickle cell disease, where treatment with steroids was helpful.
authors.affiliation: Division of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, USA. zarjr73@yahoo.com
authors.forename: Tausif
authors.initials: T
authors.lastname: Zar
authors.forename: Jayapriya
authors.initials: J
authors.lastname: Krishnaswamy
authors.forename: Harold T
authors.initials: HT
authors.lastname: Yamase
authors.forename: Wilner
authors.initials: W
authors.lastname: Samson
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D049590:Postpartum Period