title: Odor discrimination using neural decoding of the main olfactory bulb in rats.
abstract: This paper presents a novel method for inferring the odor based on neural activities observed from rats' main olfactory bulbs. Multichannel extracellular single unit recordings were done by microwire electrodes (tungsten, 50 μm, 32 channels) implanted in the mitral/tufted cell layers of the main olfactory bulb of anesthetized rats to obtain neural responses to various odors. Neural response as a key feature was measured by subtraction of neural firing rate before stimulus from after. For odor inference, we have developed a decoding method based on the maximum likelihood estimation. The results have shown that the average decoding accuracy is about 100.0%, 96.0%, 84.0%, and 100.0% with four rats, respectively.
authors.affiliation: Department of Electronic Engineering, College of IT, Soongsil University, Seoul 156-743, Korea. fabricc@gmail.com
authors.forename: Kyung-Jin
authors.initials: KJ
authors.lastname: You
authors.forename: Hyoung Geol
authors.initials: HG
authors.lastname: Ham
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Lee
authors.forename: Yiran
authors.initials: Y
authors.lastname: Lang
authors.forename: Changkyun
authors.initials: C
authors.lastname: Im
authors.forename: Chin Su
authors.initials: CS
authors.lastname: Koh
authors.forename: Mi-Yeon
authors.initials: MY
authors.lastname: Kim
authors.forename: Hyung-Cheul
authors.initials: HC
authors.lastname: Shin
authors.forename: Hyun-Chool
authors.initials: HC
authors.lastname: Shin
mesh_terms: D000465:Algorithms; D000818:Animals; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods*; D005071:Evoked Potentials / Q000502:physiology; D008297:Male; D015233:Models, Statistical; D009812:Odorants; D009830:Olfactory Bulb / Q000502:physiology*; D009930:Organic Chemicals; D051381:Rats; D017207:Rats, Sprague-Dawley; D012815:Signal Processing, Computer-Assisted; D012903:Smell / Q000502:physiology
chemical_list: D009930:Organic Chemicals