title: Extensive visceral calcification demonstrated on Tc-99m MDP bone scan in patient with sphenoidal sinus carcinoma and hypercalcaemia of malignancy: a bad prognostic sign.
abstract: Sphenoidal sinus carcinoma is a rare cause of hypercalcemia of malignancy. We report on a 37-year-old male with sphenoidal sinus carcinoma with intracranial extension who developed hypercalcemia of malignancy with progressing disease and demonstrated diffuse metastatic visceral calcifications of lungs, myocardium, stomach, kidneys and thyroid on follow-up 99mTc-methylene diphosphonate bone scan. In the absence of extensive skeletal metastases, bone scan help confirm humoral nature of hypercalcaeimia.
authors.affiliation: Kuwait Department of Nuclear Medicine, Hussain Makki Al Jumma Centre for Specialized Surgery, Khaitan, Kuwait. dr_shajji@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Usmani
authors.forename: H A
authors.initials: HA
authors.lastname: Khan
authors.forename: F
authors.initials: F
authors.lastname: Abu Huda
authors.forename: N
authors.initials: N
authors.lastname: Al Nafisi
authors.forename: S
authors.initials: S
authors.lastname: Al Mohannadi
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008297:Male; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging*; D011379:Prognosis; D011877:Radionuclide Imaging; D013101:Sphenoid Sinus; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate