title: Prevalence of vitreous hemorrhage following coronary revascularization in patients with diabetic retinopathy.
abstract: BACKGROUND
  In patients with diabetic retinopathy (DR), vitreous hemorrhage (VH) is a common complication that threatens visual acuity and hence, quality of life. A considerable number of DR patients at risk of VH require coronary revascularization, but little is known about the prevalence of VH after coronary revascularization.
  
  
  RESULTS
  This study investigated 151 patients with DR who were followed up by ophthalmologists between April 2004 and September 2008, and underwent coronary revascularization (coronary artery bypass surgery n=36 or drug-eluting stent implantation n=115). At the time of coronary revascularization 56 had non-proliferative DR (NPDR) and 95 had proliferative DR (PDR). During an average follow-up of 531 days after revascularization, VH occurred in 24 (15.9%) patients, 18 (11.9%) of whom experienced VH within 6 months of the procedure. In VH patients, PDR rather than NPDR predominated as the background to VH (21 vs. 3, respectively). The 1-year prevalence of VH was higher in patients with PDR than in those with NPDR (22.0% vs. 1.9%, P=0.0055).
  
  
  CONCLUSIONS
  VH is not a rare complication following coronary revascularization among patients with DR, especially in those with PDR. Thus, in terms of maintaining quality of life, VH after coronary revascularization needs further attention in these patients.
authors.affiliation: Department of Cardiothoracic Surgery, The University of Tokyo, Tokyo, Japan. ana16892@hotmail.co.jp
authors.forename: Dai
authors.initials: D
authors.lastname: Kawashima
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ohno
authors.forename: Osamu
authors.initials: O
authors.lastname: Kinoshita
authors.forename: Noboru
authors.initials: N
authors.lastname: Motomura
authors.forename: Arihiro
authors.initials: A
authors.lastname: Kiyosue
authors.forename: Hideo
authors.initials: H
authors.lastname: Fujita
authors.forename: Jiro
authors.initials: J
authors.lastname: Ando
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Ohtomo
authors.forename: Takashi
authors.initials: T
authors.lastname: Shigeeda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kato
authors.forename: Takashi
authors.initials: T
authors.lastname: Kadowaki
authors.forename: Ryozo
authors.initials: R
authors.lastname: Nagai
authors.forename: Shinichi
authors.initials: S
authors.lastname: Takamoto
authors.forename: Minoru
authors.initials: M
authors.lastname: Ono
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000601:surgery / Q000628:therapy; D003930:Diabetic Retinopathy / Q000150:complications*; D004198:Disease Susceptibility; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015995:Prevalence; D016016:Proportional Hazards Models; D011788:Quality of Life; D018630:Vitreoretinopathy, Proliferative / Q000150:complications*; D014823:Vitreous Hemorrhage / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control