title: Correlation between visual prognosis and fundus autofluorescence and optical coherence tomographic findings in highly myopic eyes with submacular hemorrhage and without choroidal neovascularization.
abstract: OBJECTIVE
  To determine whether a significant correlation existed between the visual prognosis and fundus autofluorescence and optical coherence tomographic images in highly myopic eyes with simple macular bleeding.
  
  
  METHODS
  We reviewed the charts of 31 eyes of 28 patients with high myopia and simple bleeding. The patients were divided into those whose best-corrected visual acuity (BCVA) was 20/32 and those with BCVA <20/32 at 6 months after absorption of the hemorrhage.
  
  
  RESULTS
  At 6 months, 19 eyes had BCVA ≥0.7 and 12 eyes had BCVA <0.7. In the former group, the inner segment/outer segment line of photoreceptors was intact in optical coherence tomographic images at the onset but was defective in 75% of the eyes in the latter group. At 6 months, the inner segment/outer segment defect was absent in all the eyes in the former group but was observed in 67% of the latter group. A hypoautofluorescence was present at the area of the bleeding more frequently in the poor BCVA groups.
  
  
  CONCLUSIONS
  An inner segment/outer segment defect at the onset of simple bleeding might be a useful sign to predict a limited visual recovery. The persistent hypofluorescence in fundus autofluorescence is probably caused by damage to the retinal pigment epithelium by the subretinal hemorrhage.
authors.affiliation: Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Muka
authors.initials: M
authors.lastname: Moriyama
authors.forename: Kyoko
authors.initials: K
authors.lastname: Ohno-Matsui
authors.forename: Noriaki
authors.initials: N
authors.lastname: Shimada
authors.forename: Kengo
authors.initials: K
authors.lastname: Hayashi
authors.forename: Ariko
authors.initials: A
authors.lastname: Kojima
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Takashi
authors.initials: T
authors.lastname: Tokoro
authors.forename: Manabu
authors.initials: M
authors.lastname: Mochizuki
mesh_terms: D000293:Adolescent; D000328:Adult; D020256:Choroidal Neovascularization / Q000209:etiology; D005139:Eyeglasses; D005260:Female; D005453:Fluorescence; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications* / Q000503:physiopathology; D020419:Photoreceptor Cells, Vertebrate / Q000473:pathology; D011379:Prognosis; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D055815:Young Adult