title: Repeated donor lymphocyte infusions overcome a myeloid sarcoma of the stomach resulting from a relapse of acute myeloid leukemia after allogeneic cell transplantation in long-term survival of more than 10 years.
abstract: A patient with acute myeloid leukemia had a relapse with a myeloid sarcoma of the stomach 32 months after allogeneic bone marrow transplantation. The patient was treated with the first donor lymphocyte infusion (DLI) and one course of induction chemotherapy. Due to severe infectious complication after chemotherapy, the patient could not continue chemotherapy. Subsequently, the patient was treated with a total of 13 cycles of DLI at 1-2 month intervals. Complete remission was achieved and neither relapse nor graft versus host disease has occurred during a follow-up of more than 10 years.
authors.affiliation: Department of Hematology, Sapporo Hokuyu Hospital, Hokkaido, Japan. akino@med.u-toyama.ac.jp
authors.forename: Akinori
authors.initials: A
authors.lastname: Wada
authors.forename: Naoki
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Asanuma
authors.forename: Satomi
authors.initials: S
authors.lastname: Matsuoka
authors.forename: Mizuha
authors.initials: M
authors.lastname: Kosugi
authors.forename: Shiro
authors.initials: S
authors.lastname: Fujii
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Noguchi
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Miyazono
authors.forename: Masanobu
authors.initials: M
authors.lastname: Nakata
authors.forename: Shuichi
authors.initials: S
authors.lastname: Ota
authors.forename: Kiyotoshi
authors.initials: K
authors.lastname: Imai
authors.forename: Teiichi
authors.initials: T
authors.lastname: Hirano
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ogasawara
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kiyama
authors.forename: Masaharu
authors.initials: M
authors.lastname: Kasai
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D017710:Lymphocyte Transfusion; D016609:Neoplasms, Second Primary / Q000628:therapy*; D012074:Remission Induction; D023981:Sarcoma, Myeloid / Q000628:therapy*; D013274:Stomach Neoplasms / Q000628:therapy*; D014019:Tissue Donors; D014184:Transplantation, Homologous