title: Beta 2 antagonism in acute respiratory failure.
abstract: Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of beta-blocker therapy in patients admitted with acute respiratory failure.
authors.affiliation: Regional Intensive Care Unit, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland.
authors.forename: Rob
authors.initials: R
authors.lastname: Mac Sweeney
authors.forename: P J
authors.initials: PJ
authors.lastname: Devereaux
authors.forename: Daniel F
authors.initials: DF
authors.lastname: McAuley
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D005260:Female; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D012131:Respiratory Insufficiency / Q000188:drug therapy* / Q000401:mortality*
chemical_list: D000319:Adrenergic beta-Antagonists