title: Catecholaminergic polymorphic ventricular tachycardia with associated sinus node dysfunction.
abstract: An 11-year-old Nepalese male child presented with history of recurrent abrupt episodes of syncope for the last one year. There was no family history of sudden death at a young age in his family. ECG at base-line revealed an isorhythmic AV dissociation with a heart rate of 50 bpm and a normal QTc. Echocardiography of the heart was normal. His 24 hour holter study revealed frequent VPC's and episodes of polymorphic ventricular tachycardia. Exercise stress test provoked a polymorphic VT. On EP study, sinus node recovery time (SNRT) was prolonged and ventricular tachycardia (VT) was induced on Isoproterenol infusion. He was treated with a permanent pacemaker and beta-blocker.
authors.affiliation: Department of Cardiology, Escort Heart Institute, New Delhi, India.
authors.forename: Pramod
authors.initials: P
authors.lastname: Joshi
authors.forename: Anil
authors.initials: A
authors.lastname: Saxena
authors.forename: Upendra
authors.initials: U
authors.lastname: Kaul
authors.forename: Aijaz H
authors.initials: AH
authors.lastname: Mansoor
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D002648:Child; D004562:Electrocardiography; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D012804:Sick Sinus Syndrome / Q000150:complications* / Q000175:diagnosis; D013575:Syncope / Q000209:etiology; D017180:Tachycardia, Ventricular / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy
chemical_list: D000319:Adrenergic beta-Antagonists