title: [Pandemic influenza surveillance in the valencian community and seasonal influenza vaccines].
abstract: BACKGROUND
  Surveillance of Pandemic influenza was carried out in the Valencian Community. Some effectiveness studies of the seasonal vaccine for AnH1N1 virus have presented no consistent results. The objective of the work consists on describing the results of the epidemic surveillance and effectiveness of the seasonal vaccine for pandemic influenza in the weeks 28 to 51, 2009.
  
  
  METHODS
  We studied the cases in primary care, hospitalized confirmed, Polimerase Chain Reaction (PCR) and viral isolates and vaccine coverage. Vaccine effectiveness was calculated by the Farrington method of screening method, in three age groups, and two periods: vaccinated 2008-9 and 2009-10 seasons.
  
  
  RESULTS
  In the first period (weeks 28-40) the incidence rates were highest in the group of 15-64 years (7207 cases), followed by those under 15 years (1596 cases). In the second period (weeks 45-47) children under 15 years (28218 cases) were the most affected. In both periods incidence in patients older than 65 years was low (rates of 56,3 and 125,1 respectively). In the studied period (weeks 28 at 51) 5481 cases were confirmed, of those that 1746 (31,8%) were hospitalized. The curve of hospitalization rate showed a profile similar to those in primary care and also in microbiological surveillance of the virus. The vaccine effectiveness in the second period was 25% in adults between 15 and 64 years and 51% in those older than 64 years.
  
  
  CONCLUSIONS
  There is an age-dependent protection with positive vaccine efficacy in the elderly, although it may be confounded by natural exposure to the virus, previous immunizations or immune response.
authors.affiliation: Área de Epidemiología, Dirección General de Salud Pública, Consellería de Sanitat de la Comunitat Valenciana, Valencia, Spain. silvia.fermamdez@salud.madrid.org
authors.forename: Rosa María
authors.initials: RM
authors.lastname: Carbó Malonda
authors.forename: Francisco
authors.initials: F
authors.lastname: González Morán
authors.forename: Hermelinda
authors.initials: H
authors.lastname: Vanaclocha Luna
authors.forename: Miguel
authors.initials: M
authors.lastname: Martín-Sierra Balibrea
authors.forename: Silvia
authors.initials: S
authors.lastname: Guiral Rodrigo
authors.forename: Elvira
authors.initials: E
authors.lastname: Pérez Pérez
authors.forename: Teresa
authors.initials: T
authors.lastname: Castellanos Martínez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control*; D008875:Middle Aged; D058873:Pandemics; D011159:Population Surveillance; D012621:Seasons; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines