title: Staphylococcal scalded skin syndrome after intra-articular injection of hyaluronic acid.
abstract: One of the severe adverse effects of intra-articular injection in the knee is septic arthritis of the knee joint. Staphylococcus aureus is the most frequent pathogen of septic arthritis. Staphylococcal scalded skin syndrome (SSSS) refers to a spectrum of blistering skin diseases caused by S. aureus exfoliative toxins. Although SSSS is rarely observed in adults, the mortality rate is high in adult cases. We report a case of SSSS due to septic knee arthritis after intra-articular hyaluronic acid injections.
authors.affiliation: Department of Orthopaedic Surgery, Osaka University, Graduate School of Medicine, Yamadaoka 2-2, Suita, Osaka, Japan. kunugiza@ort.med.osaka-u.ac.jp
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kunugiza
authors.forename: Mamori
authors.initials: M
authors.lastname: Tani
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tomita
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D001706:Biopsy; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D007270:Injections, Intra-Articular / Q000009:adverse effects; D008279:Magnetic Resonance Imaging; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D011859:Radiography; D013206:Staphylococcal Scalded Skin Syndrome / Q000209:etiology* / Q000473:pathology / Q000635:transmission*; D055675:Viscosupplements / Q000008:administration & dosage*
chemical_list: D055675:Viscosupplements; D006820:Hyaluronic Acid