title: Infliximab for idiopathic deep cutaneous vasculitis refractory to cyclophosphamide.
abstract: Cutaneous vasculitis can be classified as primary or idiopathic; or secondary, when it presents as a manifestation of connective tissue diseases, infections, drug reactions or malignancies. Although most of the idiopathic cases are self-limited and responsive to supportive measures and nonsteroidal anti-inflammatory drugs, potent immunosuppressants are sometimes required for the management of the refractory situations. Here we describe a case of a 32-year-old Caucasian female patient with history of idiopathic cutaneous deep vasculitis unresponsive to methotrexate, dapsone, and cyclophosphamide who was effectively treated with infliximab.
authors.affiliation: Universidade Estadual de Ponta Grossa (UEPG), Rua Carlos Osternack, 111, 84040120, Ponta Grossa, Paraná, Brazil.
authors.forename: Marcelo Derbli
authors.initials: MD
authors.lastname: Schafranski
authors.forename: Giuliano Doretto
authors.initials: GD
authors.lastname: Campanari