title: [Treatment recommendations for adrenal metastasis of non-small cell lung cancer].
abstract: To evaluate the optimum treatment strategy for metastatic adrenal tumors derived from non-small cell lung cancer (NSCLC), we retrospectively analyzed 17 consecutive cases (8 resection cases: 4 synchronous and 4 metachronous: 9 non-resection cases: 3 synchronous and 6 metachronous) who received surgical resection for NSCLC. The patients included 12 males and 5 females with a mean age of 63.9 years. Of these, 9, 3, 2, 2, and 1 patient (s) were diagnosed as having adenocarcinoma, squamous cell carcinoma, pleomorphic carcinoma, large cell carcinoma, and adenosquamous cell carcinoma, respectively. The mean interval after lung resection and treatment of metachronous adrenal metastasis was 9.9 months. The mean time to progression from treatment of metachronous adrenal metastasis to disease progression was 8.9 months. A survival analysis showed no significant prognostic difference between the patient age, gender, pathological stage, synchronous/metachronous classification, CEA, and site of metastases. However, patients who received an adrenalectomy had a more favorable prognosis. The 2-year survival of patients following resection versus those who did not undergo a resection for adrenal metastasis was 62.5 and 22.8%, respectively. These data indicate that metastatic adrenal tumors should be resected if the patient can tolerate surgery after appropriate selection.
authors.affiliation: Department of Thoracic Surgery, Niigata Rosai Hospital, Joetsu, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Iwanami
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Uramoto
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Baba
authors.forename: Masaru
authors.initials: M
authors.lastname: Takenaka
authors.forename: Erina
authors.initials: E
authors.lastname: Yokoyama
authors.forename: Soichi
authors.initials: S
authors.lastname: Oka
authors.forename: Tetsuya
authors.initials: T
authors.lastname: So
authors.forename: Kenji
authors.initials: K
authors.lastname: Ono
authors.forename: Tomoko
authors.initials: T
authors.lastname: So
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Takenoyama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hanagiri
authors.forename: Teruo
authors.initials: T
authors.lastname: Iwata
authors.forename: Masaaki
authors.initials: M
authors.lastname: Inoue
authors.forename: Kosei
authors.initials: K
authors.lastname: Yasumoto
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy*; D000315:Adrenalectomy; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D012189:Retrospective Studies