title: [Immune status of patients with exacerbation of chronic suppurative otitis media and its correction].
abstract: The authors report results of a clinical and immunological study involving 38 patients with exacerbation of chronic suppurative otitis media. It has demonstrated high immunological and clinical efficiency of combined treatment with derinate (an agent stimulating local immunity) and high molecular-weight polypeptide polyoxidonium. It is concluded that inclusion of these drugs in combined therapy of chronic suppurative otitis media increases its immunological and clinical effectiveness and allows duration of patients' hospitalization to be reduced.
authors.forename: A M
authors.initials: AM
authors.lastname: Zemskov
authors.forename: A V
authors.initials: AV
authors.lastname: Kiselev
authors.forename: V V
authors.initials: VV
authors.lastname: Koveshnikov
mesh_terms: D002908:Chronic Disease; D004247:DNA / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007109:Immunity / Q000187:drug effects; D007155:Immunologic Factors / Q000627:therapeutic use*; D010035:Otitis Media, Suppurative / Q000188:drug therapy* / Q000276:immunology*; D010879:Piperazines / Q000627:therapeutic use*; D011108:Polymers / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: C541364:Derinat; D007155:Immunologic Factors; D010879:Piperazines; D011108:Polymers; D004247:DNA; C540909:azoximer bromide