title: Cutaneous adenolipoma: extending the spectrum of changes in the lipomatous and epithelial components.
abstract: Adenolipoma refers to a variant of a lipoma with entrapped eccrine or, rarely, apocrine units. We present 5 cases of cutaneous adenolipoma to demonstrate the spectrum of changes in the lipomatous and epithelial components. The cases include 3 lesions having a conventional lipomatous element and 1 with a spindle cell lipomatous component, each additionally featuring entrapped minimally altered eccrine units. In the remaining case, the epithelial component manifested a combination of hyperplastic and metaplastic changes (clear cell and squamous metaplasia) and unusually altered polarity of luminal cells with expression of myoepithelial cell markers on the luminal cells while focal absence of basal/myoepithelial cell in the corresponding area as evident microscopically and immunohistochemically.
authors.affiliation: Sikl's Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic. kazakov@medima.cz
authors.forename: Dmitry V
authors.initials: DV
authors.lastname: Kazakov
authors.forename: Dominic V
authors.initials: DV
authors.lastname: Spagnolo
authors.forename: Denisa
authors.initials: D
authors.lastname: Kacerovska
authors.forename: Werner
authors.initials: W
authors.lastname: Kempf
authors.forename: Michal
authors.initials: M
authors.lastname: Michal
mesh_terms: D000328:Adult; D004439:Eccrine Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D008067:Lipoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*