title: Neoadjuvant chemotherapy plus fertility-sparing surgery in locally advanced cervical cancer: case report.
abstract: Cervical carcinoma is the second most common malignant disease worldwide, often occurring in young women who have not completed childbearing. In this era of emphasis on conservative treatments, management of cervical cancer could be influenced by patient desire to preserve fertility, maintaining the uterine corpus. Herein is reported the case of a young woman with locally advanced cervical cancer that was successfully treated using neoadjuvant chemotherapy followed by simple vaginal trachelectomy and laparoscopic lymphadenectomy. The success of such an approach, which is not the standard of care in this disease, suggests that additional studies should be performed in a selected population.
authors.affiliation: Department of Obstetrics and Gynecology, University of Rome La Sapienza, Rome, Italy. innocenza.palaia@uniroma1.it
authors.forename: Innocenza
authors.initials: I
authors.lastname: Palaia
authors.forename: Angela
authors.initials: A
authors.lastname: Musella
authors.forename: Elisa
authors.initials: E
authors.lastname: Loprete
authors.forename: Chiara
authors.initials: C
authors.lastname: Achilli
authors.forename: Giorgia
authors.initials: G
authors.lastname: Perniola
authors.forename: Pierluigi Benedetti
authors.initials: PB
authors.lastname: Panici
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*