title: [Two cases of Werdnig-Hofmann disease].
abstract: Spinal muscular atrophy (SMA) is an autonomic recessive disorder that affects the anterior horn cells of the spinal cord, degeneration of which results in proximal muscle weakness. It is classified into three types: I and II (Werdnig-Hoffmann disease) and III (Kugelberg-Welander disease). With an incidence of 1/10,000. We report two cases of infants with hypotonic syndrome, that were diagnose with SMA, in the first case by muscular biopsy, and in the second by electromyography and chromosomes study. It is import that the physicians know about this disease, and its complications.
authors.affiliation: Instituto Mexicano del Seguro Social, Mexicali, Baja California, Mexico. yusvip@yahoo.com
authors.forename: Yusvisaret
authors.initials: Y
authors.lastname: Palmer-Morales
authors.forename: Gabriela
authors.initials: G
authors.lastname: Pacheco-Flores
authors.forename: Yasmyn
authors.initials: Y
authors.lastname: Ames-Guevara
authors.forename: Martín
authors.initials: M
authors.lastname: Gaxiola-Apodaca
authors.forename: Daniela
authors.initials: D
authors.lastname: Gaspar-Franco
authors.forename: Guillermo
authors.initials: G
authors.lastname: Landavazo-Acuña
authors.forename: Federico
authors.initials: F
authors.lastname: Hernández-Rocha
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014897:Spinal Muscular Atrophies of Childhood / Q000175:diagnosis