title: [Effect of the degree of muscle relaxation on motor-evoked potential elicited by transcranial electrical stimulation in spine surgery].
abstract: OBJECTIVE
  To study the effect of the degree of muscle relaxation on motor-evoked potential elicited by transcranial electrical stimulation in patients undergoing spine surgery.
  
  
  METHODS
  Sixty ASA I or II patients undergoing spine surgery were randomly divided into 5 groups (n=12). After an initial intubation, continuous cisatracurium infusion was administered with continuous monitoring of T1. The infusion dose was adjusted according muscle relaxation monitoring, and different muscle relaxation degrees were maintained in the 5 groups. The band and latency of D1 in motor-evoked potential was observed with also subjective assessment of the muscle relaxation.
  
  
  RESULTS
  Significant differences in the band and latency were noted in groups I and II compared with the reference values, but not in groups III, IV and V. Subjective assessment revealed significant differences between groups IV and V and groups I and III in terms of the number of cases with poor muscle relaxation.
  
  
  CONCLUSIONS
  T1 value between 10% and 15% is sufficient for MEP monitoring and allows the maintenance of good muscle relaxation during spine surgery.
authors.affiliation: Department of Anesthesiology, Third Affiliated Hospital of Southern Medical University, Guangzhou, China. 247503777@qq.com
authors.forename: Chuan-xiang
authors.initials: CX
authors.lastname: Li
authors.forename: Fu-hu
authors.initials: FH
authors.lastname: Song
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.forename: Da-di
authors.initials: DD
authors.lastname: Jing
authors.forename: Dong-mei
authors.initials: DM
authors.lastname: Song
authors.forename: Li
authors.initials: L
authors.lastname: Chen
mesh_terms: D001279:Atracurium / Q000627:therapeutic use; D004558:Electric Stimulation; D019054:Evoked Potentials, Motor; D006801:Humans; D016343:Monitoring, Intraoperative; D009126:Muscle Relaxation; D003473:Neuromuscular Nondepolarizing Agents / Q000627:therapeutic use; D019637:Orthopedic Procedures / Q000379:methods*; D013131:Spine / Q000601:surgery
chemical_list: D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium