title: [Intervention of nutritional status and hypoxia endurance by a nutritional supplement in young adults living at high altitude].
abstract: OBJECTIVE
  To investigate the effects of a nutritional supplement on nutritional status and hypoxia endurance in young adults living at high altitude.
  
  
  METHODS
  Forty healthy male young adults were recruited and randomly assigned to control and intervention groups. The nutrition survey was carried out using weighing method. The intervention group was given a nutritional supplement specifically designed for use at high altitude, while the control group was treated with a supplement made of stir-fried flour. After 20 days of supplementation, they marched from the altitude of 3700 m to 5100 m. The changes in HR, SaO2, serum concentrations of VA and VB2 and some minerals were measured.
  
  
  RESULTS
  The results of nutrition survey showed that the ratio of three macronutrients was not adequate and the intakes of calcium, VA and VB2 were below Chinese RNI. The serum concentrations of calcium, magnesium and VA were below normal references. The serum VB2 concentration was at the low level o f normal reference. The nutritional supplement could increase the serum concentrations of calcium, magnesium, VA and VB2, indicating an improved nutritional status. The changes in HR and SaO2 were diminished in intervention group compared with control group.
  
  
  CONCLUSIONS
  The nutritional supplement can improve nutritional status and increase the hypoxia endurance in young adults living at high altitude.
authors.affiliation: Institute of Health and Environmental Medicine, Tianjin 300050, China.
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Wei
authors.forename: Chang-jiang
authors.initials: CJ
authors.lastname: Guo
authors.forename: Ji-jun
authors.initials: JJ
authors.lastname: Yang
authors.forename: Yin-zhi
authors.initials: YZ
authors.lastname: Xie
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Cui
authors.forename: Xi-zhou
authors.initials: XZ
authors.lastname: Zhang
authors.forename: Bao-yu
authors.initials: BY
authors.lastname: Luo
mesh_terms: D000328:Adult; D000531:Altitude; D019587:Dietary Supplements; D006801:Humans; D000860:Hypoxia / Q000517:prevention & control*; D008297:Male; D009752:Nutritional Status; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D014815:Vitamins