title: Endoscopic low-coherence topography measurement for upper airways and hollow samples.
abstract: To evaluate the severity of airway pathologies, quantitative dimensioning of airways is of utmost importance. Endoscopic vision gives a projective image and thus no true scaling information can be directly deduced from it. In this article, an approach based on an interferometric setup, a low-coherence laser source and a standard rigid endoscope is presented, and applied to hollow samples measurements. More generally, the use of the low-coherence interferometric setup detailed here could be extended to any other endoscopy-related field of interest, e.g., gastroscopy, arthroscopy and other medical or industrial applications where tri-dimensional topology is required. The setup design with a multiple fibers illumination system is presented. Demonstration of the method ability to operate on biological samples is assessed through measurements on ex vivo pig bronchi.
authors.affiliation: Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. yves.delacretaz@epfl.ch
authors.forename: Yves
authors.initials: Y
authors.lastname: Delacretaz
authors.forename: Etienne
authors.initials: E
authors.lastname: Shaffer
authors.forename: Nicolas
authors.initials: N
authors.lastname: Pavillon
authors.forename: Jonas
authors.initials: J
authors.lastname: Kuhn
authors.forename: Florian
authors.initials: F
authors.lastname: Lang
authors.forename: Christian
authors.initials: C
authors.lastname: Depeursinge
mesh_terms: D000818:Animals; D019723:Endoscopes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000295:instrumentation*; D007368:Interferometry / Q000295:instrumentation*; D008168:Lung / Q000033:anatomy & histology*; D019047:Phantoms, Imaging; D013552:Swine; D041623:Tomography, Optical Coherence / Q000295:instrumentation*