title: Anaesthetic management of a patient with Liddle's syndrome for emergency caesarean hysterectomy.
abstract: We describe the anaesthetic management of a patient with Liddle's syndrome during caesarean section and emergency hysterectomy for placenta accreta associated with significant intrapartum haemorrhage. Liddle's syndrome is a rare autosomal dominant disorder characterised by early onset arterial hypertension and hypokalaemic metabolic alkalosis. Additional issues were the presence of short stature, limb hypertonicity and preeclampsia. Initial management with a low-dose combined spinal-epidural technique was subsequently converted to general anaesthesia due to patient discomfort. The management of Liddle's syndrome in the setting of neuraxial and general anaesthesia in a patient undergoing caesarean section is discussed.
authors.affiliation: Department of Anaesthesia, Rotunda Hospital, Dublin, Ireland. nihayes@rotunda.ie
authors.forename: N E
authors.initials: NE
authors.lastname: Hayes
authors.forename: A
authors.initials: A
authors.lastname: Aslani
authors.forename: C L
authors.initials: CL
authors.lastname: McCaul
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000775:Anesthesia, Spinal; D002245:Carbon Dioxide / Q000097:blood; D002585:Cesarean Section; D004630:Emergencies; D005260:Female; D006801:Humans; D007044:Hysterectomy; D056929:Liddle Syndrome / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*
chemical_list: D002245:Carbon Dioxide