title: National and international interlaboratories comparisons: a tool for the validation of in vitro and in vivo methods.
abstract: The metrological evaluation is indispensable to objectively prove the capability of the medical laboratory to perform analysis. The comparison of analytical performances regarding the accuracy and the reproducibility of the available methods is a real interest of international comparison exercises, especially as the participation to comparison exercises is becoming a requirement for accredited laboratories. Interlaboratory tests are a means of assessing the analytical coherence of medical laboratories. In radiotoxicology, this kind of exercise makes it possible to keep up with laboratory know-how and with the evolution and relative performances of analytical techniques. The objective of this paper will be to present and discuss the main principle of proficiency testing in radiobioassay field illustrated by exercises organised in France for in vivo monitoring and for in vitro analysis.
authors.affiliation: CEA/DSV/prositon, BP6 92265 Fontenay-aux-Roses Cedex, France. philippe.berard@cea.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Bérard
authors.forename: Didier
authors.initials: D
authors.lastname: Franck
mesh_terms: D002138:Calibration; D019411:Clinical Laboratory Techniques; D005602:France; D006801:Humans; D066298:In Vitro Techniques; D007391:International Cooperation; D007753:Laboratories / Q000592:standards*; D015233:Models, Statistical; D019047:Phantoms, Imaging; D011786:Quality Control; D011834:Radiation Monitoring / Q000379:methods / Q000592:standards*; D011853:Radiobiology / Q000379:methods; D011874:Radiometry / Q000379:methods / Q000592:standards*; D015203:Reproducibility of Results