title: [Factors influencing leukemic dendritic cell cultivation in vitro-- review].
abstract: Leukemic dendritic cells, compared to normal dendritic cells, have the similar surface molecules, but have poor antigen-presenting function. When inoculated in the human body, the dendritic cells can not produce enough immune response. Therefore, how to make dendritic cells mature and have its own function to play a better anti-leukemia immune response is the key problem in clinical treatment. And it is one of the hottest studies in the immunotherapy field. This review focuses the recent progress of research on the culture of dendritic cells in vitro, its influence factors and so on.
authors.affiliation: Department of Hematology, Southeast University Medical Cellege, Bengbu 233000, Anhui Province, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Gui
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Bao-An
authors.initials: BA
authors.lastname: Chen
mesh_terms: D018929:Cell Culture Techniques; D002454:Cell Differentiation; D003713:Dendritic Cells / Q000166:cytology*; D006801:Humans; D007167:Immunotherapy; D007938:Leukemia / Q000276:immunology / Q000628:therapy