title: N-aminoazetidinecarboxylic acid: direct access to a small-ring hydrazino acid.
abstract: A short and efficient synthesis of the previously unknown N-aminoazetidinecarboxylic acid has been established using a photochemical [2 + 2] cycloaddition strategy starting from 6-azauracil. Chiral derivatization with a nonracemic oxazolidinone provided access to both enantiomers of the title product.
authors.affiliation: Laboratoire de Synthèse Organique et Méthodologie, ICMMO (UMR 8182-CNRS), Université Paris-Sud 11, 15 rue Georges Clemenceau, 91405 Orsay cedex, France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Declerck
authors.forename: David J
authors.initials: DJ
authors.lastname: Aitken
mesh_terms: D001383:Azetidinecarboxylic Acid / Q000138:chemical synthesis* / Q000737:chemistry*; D006834:Hydrazines / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D023303:Oxazolidinones / Q000737:chemistry; D013237:Stereoisomerism; D014498:Uracil / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D006834:Hydrazines; D023303:Oxazolidinones; D014498:Uracil; D001383:Azetidinecarboxylic Acid; C100248:azauracil