title: Pathologic characteristics of hysterectomy specimens in women undergoing hysterectomy after global endometrial ablation.
abstract: OBJECTIVE
  To describe uterine pathologic features in women who underwent hysterectomy because of failed global endometrial ablation (GEA).
  
  
  METHODS
  Retrospective cohort study from 1998 through 2005 (Canadian Task Force classification III).
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  Sixty-nine women who underwent hysterectomy because of GEA failure.
  
  
  METHODS
  Pathology reports were available for 67 patients. Descriptions of hysterectomy specimens after GEA were reviewed.
  
  
  RESULTS
  Rates of pathologic findings in hysterectomy specimens after failed GEA were determined. Reasons for hysterectomy in the 67 patients with available pathology reports were bleeding in 34 (51%), pain in 19 (28%), and bleeding and pain in 14 (21%). The pathology reports of these specimens showed leiomyomas in 33 specimens (49%); intramural myomas were present in 15 women (44%) who underwent hysterectomy because of bleeding and 8 women (42%) who underwent hysterectomy because of pain. Hematometra was identified in 7 pathologic specimens (10%). Specifically, hematometra was identified in specimens from 5 of 19 women who underwent hysterectomy because of pain (26%).
  
  
  CONCLUSIONS
  Hematometra was a significant finding in women who underwent hysterectomy because of persistent pain after GEA. A possible pathologic predictor of GEA failure may be intramural leiomyomas.
authors.affiliation: Department of Obstetrics and Gynecology, University of North Carolina, NC, USA.
authors.forename: Erin T
authors.initials: ET
authors.lastname: Carey
authors.forename: Sherif A
authors.initials: SA
authors.lastname: El-Nashar
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Hopkins
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Creedon
authors.forename: William A
authors.initials: WA
authors.lastname: Cliby
authors.forename: Abimbola O
authors.initials: AO
authors.lastname: Famuyide
mesh_terms: D000328:Adult; D055356:Endometrial Ablation Techniques / Q000009:adverse effects*; D005260:Female; D006409:Hematometra / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D007044:Hysterectomy; D008595:Menorrhagia / Q000601:surgery; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome