title: Evaluation of anthelmintic activity of liquid waste of Agave sisalana (sisal) in goats.
abstract: It was evaluated the anthelmintic activity of Agave sisalana (sisal) juice against gastrointestinal nematodes and its potential toxic effects in goats. In vitro tests showed more than 95% reduction in larval counts of the genus Haemonchus spp. at concentrations between 86.5 and 146.3 mg.mL(-1). In vivo the percent reduction of larvae of the fourth (L4) and fifth (L5) stages of Haemonchus, Oesophagostomum and Trichostrongylus was less than 95% in groups GI and GII, and between 80 and 90% in group GIII. A. sisalana juice at the concentrations tested in vitro was effective against gastrointestinal nematodes in goats; however, its anthelmintic efficacy was reduced when administered to animals.
authors.affiliation: Escola de Medicina Veterinária, Universidade Federal da Bahia, Rua Luiz Gama no. 7-07, Independência, Bauru-SP, Brazil. lucianafd@hotmail.com
authors.forename: Luciana Ferreira
authors.initials: LF
authors.lastname: Domingues
authors.forename: Mariana Borges
authors.initials: MB
authors.lastname: Botura
authors.forename: Ana Carla Ferreira Guedes da
authors.initials: AC
authors.lastname: Cruz
authors.forename: Cristiane Carina
authors.initials: CC
authors.lastname: Yuki
authors.forename: Gisele Dias da
authors.initials: GD
authors.lastname: Silva
authors.forename: Márcia Silva
authors.initials: MS
authors.lastname: Costa
authors.forename: Gleeson
authors.initials: G
authors.lastname: Murphy
authors.forename: Eduardo Luiz Trindade
authors.initials: EL
authors.lastname: Moreira
authors.forename: Iris Daniela Santos de
authors.initials: ID
authors.lastname: Meneses
authors.forename: Maria das Graças Ávila Ribeiro de
authors.initials: Md
authors.lastname: Almeida
authors.forename: Alexsandro
authors.initials: A
authors.lastname: Branco
authors.forename: Maria Angela Ornelas de
authors.initials: MA
authors.lastname: Almeida
authors.forename: Maria José Moreira
authors.initials: MJ
authors.lastname: Batatinha
mesh_terms: D027882:Agave; D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D015511:Goat Diseases / Q000188:drug therapy; D006041:Goats / Q000469:parasitology*; D009348:Nematoda / Q000187:drug effects* / Q000302:isolation & purification; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D008517:Phytotherapy; D028321:Plant Preparations / Q000494:pharmacology*
chemical_list: D000871:Anthelmintics; D028321:Plant Preparations