title: Miscarriage karyotype and its relationship with maternal body mass index, age, and mode of conception.
abstract: This study investigated the association between miscarriage karyotype and body mass index, maternal age, and mode of conception. Miscarriages after IVF and/or intracytoplasmic sperm injection were less frequently aneuploid; advanced maternal age was associated with an increase in aneuploid products of conception; overweight and obese women aged <35 years were less likely to have aneuploid miscarriages than women in a healthy weight range, suggesting alternate mechanisms for miscarriage in this population.
authors.affiliation: Queensland Fertility Group Research Fondation, Brisbane, Queensland, Australia. rkippen@unimelb.edu.au
authors.forename: Ben
authors.initials: B
authors.lastname: Kroon
authors.forename: Keith
authors.initials: K
authors.lastname: Harrison
authors.forename: Nicole
authors.initials: N
authors.lastname: Martin
authors.forename: Brittany
authors.initials: B
authors.lastname: Wong
authors.forename: Anusch
authors.initials: A
authors.lastname: Yazdani
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D000328:Adult; D000782:Aneuploidy; D015992:Body Mass Index; D002869:Chromosome Aberrations / Q000706:statistics & numerical data; D005260:Female; D005306:Fertilization / Q000502:physiology*; D005307:Fertilization in Vitro / Q000009:adverse effects / Q000706:statistics & numerical data; D006801:Humans; D007621:Karyotyping; D008423:Maternal Age; D009035:Mothers; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000235:genetics / Q000473:pathology; D050177:Overweight / Q000150:complications / Q000235:genetics / Q000473:pathology; D011247:Pregnancy; D055815:Young Adult