title: A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates.
abstract: Reagentless, sensitive and multiplexed analysis of gyrB and K-ras gene biomarkers is achieved based on the proximity changes of two different redox-tags to the electrode surface upon DNA hybridizations, and the presence of the two gene biomarkers also acts as inputs and activates the logic gate.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yunatswu@swu.edu.cn
authors.forename: Yun
authors.initials: Y
authors.lastname: Xiang
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Qian
authors.forename: Ying
authors.initials: Y
authors.lastname: Chen
authors.forename: Yuyong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D015374:Biosensing Techniques / Q000191:economics / Q000379:methods*; D002138:Calibration; D015179:Colorectal Neoplasms / Q000235:genetics*; D027081:DNA Gyrase / Q000235:genetics*; D004566:Electrodes; D011905:Genes, ras; D005819:Genetic Markers; D006801:Humans; D009693:Nucleic Acid Hybridization; D010084:Oxidation-Reduction; D012486:Salmonella typhimurium / Q000235:genetics*; D013499:Surface Properties
chemical_list: D001426:Bacterial Proteins; D005819:Genetic Markers; D027081:DNA Gyrase