title: Analysis of UV ink photoinitiators in packaged food by fast liquid chromatography at sub-ambient temperature coupled to tandem mass spectrometry.
abstract: A fast method of liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) was developed for the analysis of eleven UV ink photoinitiators in packaged food. Chromatographic separation was achieved in a pentafluorophenylpropyl (PFPP) column at 5°C and acetonitrile:25 mM formic acid-ammonium formate (pH 2.7) in gradient elution. To reduce sample treatment, a QuEChERS (quick, easy, cheap, effective, rugged and safe) method for the extraction and clean-up of UV photoinitiators in packaged foods was evaluated. Triple quadrupole working in H-SRM on Q1 mode was used for both quantitation and confirmation purposes and the most intense and selective transitions were chosen. Quality parameters of the developed QuEChERS LC-MS/MS method were established and applied for the analysis of photoinitiators in food packaged at ng kg(-1) levels.
authors.affiliation: Department of Analytical Chemistry, University of Barcelona, Diagonal 647, 08028 Barcelona, Spain.
authors.forename: Héctor
authors.initials: H
authors.lastname: Gallart-Ayala
authors.forename: Oscar
authors.initials: O
authors.lastname: Núñez
authors.forename: Encarnación
authors.initials: E
authors.lastname: Moyano
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Galceran
mesh_terms: D001555:Benzene Derivatives / Q000032:analysis* / Q000737:chemistry; D001565:Benzoates / Q000032:analysis* / Q000737:chemistry; D002853:Chromatography, Liquid / Q000379:methods*; D003080:Cold Temperature; D018857:Food Packaging; D006863:Hydrogen-Ion Concentration; D017319:Photosensitizing Agents / Q000032:analysis* / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014466:Ultraviolet Rays
chemical_list: D001555:Benzene Derivatives; D001565:Benzoates; D017319:Photosensitizing Agents