title: Novel structural elements within the nonproteolytic clostridium botulinum type F toxin gene cluster.
abstract: We sequenced for the first time the complete neurotoxin gene cluster of a nonproteolytic Clostridium botulinum type F. The neurotoxin gene cluster contained a novel gene arrangement that, compared to other C. botulinum neurotoxin gene clusters, lacked the regulatory botR gene and contained an intergenic is element between its orfX2 and orfX3 genes.
authors.affiliation: Infant Botulism Treatment and Prevention Program, California Department of Public Health, 850 Marina Bay Parkway, Room E361, Richmond, CA 94804, USA.
authors.forename: N
authors.initials: N
authors.lastname: Dover
authors.forename: J R
authors.initials: JR
authors.lastname: Barash
authors.forename: K K
authors.initials: KK
authors.lastname: Hill
authors.forename: J C
authors.initials: JC
authors.lastname: Detter
authors.forename: S S
authors.initials: SS
authors.lastname: Arnon
mesh_terms: D003014:Clostridium botulinum / Q000235:genetics*; D047971:Clostridium botulinum type F / Q000235:genetics*; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D005810:Multigene Family; D016366:Open Reading Frames; D017422:Sequence Analysis, DNA; D014157:Transcription Factors / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D014157:Transcription Factors