title: [Insipid diabetes as initial presentation of Wegener's granulomatosis].
abstract: Wegener's granulomatosis is a granulomatous necrotizing vasculitis which predominantly affects the respiratory tract, kidney, and less frequently other organs such as the nervous system. The latter may occur in up to 54% of cases and when it does it is more frequently of the peripheral nerves. We present a 19 year old woman who commenced her disease with involvement of respiratory sinuses, lungs and kidney and who developed central insipid diabetes (CID) at onset. The CID persisted in spite of adequate response of the other organs and systems with immunosuppresor treatment. The development of CID in the context of vasculitis should suggest this as a possible mechanism.
authors.affiliation: Servicio de Clínica Médica, Hospital Italiano de Buenos Aires.
authors.forename: Lorena
authors.initials: L
authors.lastname: Narvaez Ponce
authors.forename: Judith
authors.initials: J
authors.lastname: Carrio
authors.forename: Enrique R
authors.initials: ER
authors.lastname: Soriano
authors.forename: Carlos D
authors.initials: CD
authors.lastname: Santos
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Imamura
authors.forename: Luis J
authors.initials: LJ
authors.lastname: Catoggio
mesh_terms: D020790:Diabetes Insipidus, Neurogenic / Q000209:etiology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D055815:Young Adult