title: Mathematical modelling and simulation of colorectal cancer.
abstract: To understand cancer pathology and develop effective treatment strategies play significant roles in improving cancer survival rates. In this paper, evaluations of mathematical modelling and simulation were studied and presented. Colorectal system was investigated from gene and cell levels. The Hardware Descriptive Language (HDL) package and codes were developed to simulate the cancer models. Representative codes and figures were illustrated. Results suggest that the HDL is an effective method to conduct the modelling and simulation of cancers. It is essential to develop advanced technology such as HDL modelling and simulation to improve our understandings to fight cancer and save lives.
authors.affiliation: Biomedical Engineering Graduate Program, Southern Illinois University, Carbondale, Illinois 62901, USA. manjeera@siu.edu
authors.forename: Manjeera
authors.initials: M
authors.lastname: Saripalli
authors.forename: Nazeih M
authors.initials: NM
authors.lastname: Botros
mesh_terms: D015179:Colorectal Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D003198:Computer Simulation; D006801:Humans; D008962:Models, Theoretical