title: A new era for cancer treatment: gold-nanoparticle-mediated thermal therapies.
abstract: Nanotechnology-based cancer treatment approaches potentially provide localized, targeted therapies that aim to enhance efficacy, reduce side effects, and improve patient quality of life. Gold-nanoparticle-mediated hyperthermia shows particular promise in animal studies, and early clinical testing is currently underway. In this article, the rapidly evolving field of gold nanoparticle thermal therapy is reviewed, highlighting recent literature and describing current challenges to clinical translation of the technology.
authors.affiliation: William Marsh Rice University, Dept. of Bioengineering MS-142, 6100 Main St., Houston, TX 77005-1892, USA.
authors.forename: Laura C
authors.initials: LC
authors.lastname: Kennedy
authors.forename: Lissett R
authors.initials: LR
authors.lastname: Bickford
authors.forename: Nastassja A
authors.initials: NA
authors.lastname: Lewinski
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Coughlin
authors.forename: Ying
authors.initials: Y
authors.lastname: Hu
authors.forename: Emily S
authors.initials: ES
authors.lastname: Day
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: West
authors.forename: Rebekah A
authors.initials: RA
authors.lastname: Drezek
mesh_terms: D006046:Gold / Q000737:chemistry*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009369:Neoplasms / Q000628:therapy*
chemical_list: D006046:Gold