title: Modulation of afterhyperpolarization evoked by doublets and increasing number of stimuli in rat motoneurons.
abstract: The authors studied the influence of variable stimulation patterns on parameters of afterhyperpolarization (AHP) in rat spinal motoneurons using intracellular recording of antidromic action potentials. The action potentials analyzed were evoked by either (a) a single stimulus or pair of stimuli with gradually increasing interpulse intervals (IPI) of 5-20 ms or (b) an increasing number of stimulus pulses, from 1 to 4, at a constant IPI. It was demonstrated that modulations of AHP parameters after 2 pulses depended on the IPI, whereas the most significant changes in these parameters were found after the application of 2 or 3 stimuli in a series. The authors propose that changes in the AHP parameters have functional significance for motoneuronal firing pattern and therefore for motor unit force development during tetanic contractions.
authors.affiliation: Department of Neurobiology, University School of Physical Education, Poznań, Poland. mrowczynski@awf.poznan.pl
authors.forename: Włodzimierz
authors.initials: W
authors.lastname: Mrowczynski
authors.forename: Piotr
authors.initials: P
authors.lastname: Krutki
authors.forename: Vihren
authors.initials: V
authors.lastname: Chakarov
authors.forename: Jan
authors.initials: J
authors.lastname: Celichowski
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D004558:Electric Stimulation / Q000379:methods*; D008297:Male; D009046:Motor Neurons / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000502:physiology; D013997:Time Factors