title: Human catalase: looking for complete identity.
abstract: Catalases are well studied enzymes that play critical roles in protecting cells against the toxic effects of hydrogen peroxide. The ubiquity of the enzyme and the availability of substrates made heme catalases the focus of many biochemical and molecular biology studies over 100 years. In human, this has been implicated in various physiological and pathological conditions. Advancement in proteomics revealed many of novel and previously unknown features of this mysterious enzyme, but some functional aspects are yet to be explained. Along with discussion on future research area, this mini-review compile the information available on the structure, function and mechanism of action of human catalase.
authors.affiliation: Department of Biochemistry, J. N. Medical College, Datta Meghe Insatitute of Medical Sciences (Deemed University), Wardha 442004, India. monusvm@yahoo.com
authors.forename: Madhur M
authors.initials: MM
authors.lastname: Goyal
authors.forename: Anjan
authors.initials: A
authors.lastname: Basak
mesh_terms: D002374:Catalase / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D006418:Heme / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism*
chemical_list: D006418:Heme; D006861:Hydrogen Peroxide; D002374:Catalase