title: [A case of advanced gastric cancer successfully treated with chemoradiotherapy targeting for recurrent lymph node metastasis].
abstract: The patient was a 75-year-old male, who was diagnosed with type 3 advanced gastric cancer and bulky lymph node metastasis. Two courses of neoadjuvant chemotherapy (S-1, CDDP) which showed a partial remission and distal gastrectomy were performed. Although he received S-1 medication as adjuvant chemotherapy, lymph node recurrence appeared 6 months after the operation. Radiation therapy at a total dose of 65 Gy (10MV X ray, 2.5 Gy/day × 26 Fr) selectively targeting for recurrent lymph node metastasis with S-1 medication were applied. There were no adverse effects during chemoradiation therapy and the metastatic node showed regression (30 mm to 15 mm). Sixteen months passed from chemoradiation, and the patient remains alive with no signs of relapse without any treatment after the chemoradiation. Therefore, our case suggests that chemoradiation therapy could be an effective treatment for recurrent lymph nodes metastasis in gastric cancer.
authors.affiliation: Dept. of Surgery, NTT West Osaka Hospital.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kimura
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyazaki
authors.forename: Chiwan
authors.initials: C
authors.lastname: Kim
authors.forename: Katsuki
authors.initials: K
authors.lastname: Danno
authors.forename: Naofumi
authors.initials: N
authors.lastname: Kagara
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kanoh
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tohno
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakano
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Kagawa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Takushi
authors.initials: T
authors.lastname: Monden
authors.forename: Shingi
authors.initials: S
authors.lastname: Imaoka
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009364:Neoplasm Recurrence, Local; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin