title: Merkel cell carcinoma. Pathological and molecular aspects of diagnosis and clinical features.
abstract: Merkel cell carcinoma (MCC) is an aggressive neoplasm of the skin usually developing in the elderly. The morphological and phenotypical characteristics of Merkel cell carcinoma was recently expanded by the molecular profile. The current review is a compilation of these data, which may enable better understanding of the histogenesis and potential target therapy in this rare tumour of the skin.
authors.affiliation: Department of Neuropathology and Molecular Pathology, Medical University of Gdańsk, ul. Dębinki 7, 80-210 Gdańsk. hania.majewska@amg.gda.pl
authors.forename: Hanna
authors.initials: H
authors.lastname: Majewska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Biernat
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D015266:Carcinoma, Merkel Cell / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D002869:Chromosome Aberrations; D002878:Chromosomes, Human, Pair 1; D002896:Chromosomes, Human, Pair 6; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D011379:Prognosis; D035583:Rare Diseases; D012878:Skin Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor