title: Prevalence of peripheral neuropathy and painful peripheral neuropathy in Turkish diabetic patients.
abstract: The aim of this study was to determine the prevalence of diabetic peripheral neuropathy (DPN) and neuropathic pain in diabetic patients attending university outpatient clinics in Turkey. In this multicenter cross-sectional study, neurologic examinations and nerve conduction studies along with clinical diabetic neuropathy score, and Leeds Assessment of Neuropathic Symptoms and Signs pain scale were performed on 1,113 patients (46.2% male) from 14 centers. Prevalence of DPN determined only by clinical examination was 40.4% and increased to 62.2%, by combining nerve conduction studies with clinical examination. According to Leeds Assessment of Neuropathic Symptoms and Signs scores, neuropathic pain prevalence was 16.0% in those who reported pain. Poor glycemic control, retinopathy, microalbuminuria, hyperlipidemia, diabetic foot, and foot amputation were more commonly observed in patients with DPN. Clinical DPN affected 40.4% of diabetic patients, and neuropathic pain prevalence in diabetic patient population was 14.0%. Clinical examinations and nerve conduction studies are important components for early detection and accurate diagnosis of DPN and painful DPN.
authors.affiliation: Department of Endocrinology and Metabolism, Medical School, Hacettepe University, Ankara, Turkey.
authors.forename: Tomris
authors.initials: T
authors.lastname: Erbas
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ertas
authors.forename: Aysen
authors.initials: A
authors.lastname: Yucel
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Keskinaslan
authors.forename: Mustafa
authors.initials: M
authors.lastname: Senocak
mesh_terms: D003430:Cross-Sectional Studies; D003929:Diabetic Neuropathies / Q000175:diagnosis* / Q000453:epidemiology*; D004576:Electromyography; D006801:Humans; D009431:Neural Conduction / Q000502:physiology; D010147:Pain Measurement; D010525:Peripheral Nerves / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000453:epidemiology*; D015995:Prevalence; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D014421:Turkey / Q000453:epidemiology