title: [Coccidioidomycosis in Argentina, 1892-2009].
abstract: Clinical cases of coccidioidomycosis are rare in Argentina and are generally found in the large arid precordilleran area of the country. This study aims to perform a retrospective review of all coccidioidomycosis cases documented in the country from 1892 to 2009, and to describe those occurring in the last 4 years. One hundred and twenty eight cases were documented in the 117 year-period. Since the original description of the disease in 1892 until 1939, only 6 cases were registered; between 1940 and 1999, 59 (6-14/10 yrs) and the remaining 63 (49% of total cases) occurred in the last decade. The median age of 34 patients registered in 2006-2009 was 31 years (range: 7-89), male/female ratio was 1.3:1 and 12 patients were immunocompromised. Twenty-six cases were confirmed by direct microscopy and/or culture whereas the remaining ones by serology. All isolates were identified as Coccidioides posadasii. Thirty patients lived in a vast geographic region with epicenter in Catamarca Valley. Between 2006 and 2009, annual disease incidence rates in Catamarca Province increased from historical values below 0.5/100,000 to 2/100,000 inhabitants. Such increase suggests an emergency of coccidioidomycosis in that region.
authors.affiliation: Departamento Micología, INEI, ANLIS Dr. Carlos G. Malbrán, Ciudad Autónoma de Buenos Aires. ccanteros@anlis.gov.ar
authors.forename: C E
authors.initials: CE
authors.lastname: Canteros
authors.forename: A
authors.initials: A
authors.lastname: Toranzo
authors.forename: B
authors.initials: B
authors.lastname: Ibarra-Camou
authors.forename: V
authors.initials: V
authors.lastname: David
authors.forename: S G
authors.initials: SG
authors.lastname: Carrizo
authors.forename: A
authors.initials: A
authors.lastname: Santillán-Iturres
authors.forename: J
authors.initials: J
authors.lastname: Serrano
authors.forename: N
authors.initials: N
authors.lastname: Fernández
authors.forename: P
authors.initials: P
authors.lastname: Capece
authors.forename: J
authors.initials: J
authors.lastname: Gorostiaga
authors.forename: Y A
authors.initials: YA
authors.lastname: Chacón
authors.forename: R
authors.initials: R
authors.lastname: Tonelli
authors.forename: G
authors.initials: G
authors.lastname: Boscaro
authors.forename: C
authors.initials: C
authors.lastname: Abiega
authors.forename: S
authors.initials: S
authors.lastname: Mendieta
authors.forename: C
authors.initials: C
authors.lastname: Fernández
authors.forename: A
authors.initials: A
authors.lastname: Fernández
authors.forename: R
authors.initials: R
authors.lastname: Vitale
authors.forename: P
authors.initials: P
authors.lastname: Santos
authors.forename: M R
authors.initials: MR
authors.lastname: Pizarro
authors.forename: M C
authors.initials: MC
authors.lastname: López-Joffre
authors.forename: W
authors.initials: W
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Mazza
authors.forename: G
authors.initials: G
authors.lastname: Posse
authors.forename: I N
authors.initials: IN
authors.lastname: Tiraboschi
authors.forename: R
authors.initials: R
authors.lastname: Negroni
authors.forename: G
authors.initials: G
authors.lastname: Davel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D012189:Retrospective Studies; D016036:Seroepidemiologic Studies; D014376:Tuberculosis / Q000175:diagnosis; D055815:Young Adult