title: Management of acute ischemic stroke: time is brain.
abstract: Treatment of acute ischemic stroke is time dependent and technically challenging. Sixty-four percent of hospitals in the U.S. have never given intravenous (IV) tissue plasminogen activator (tPA) for stroke and 40% of the U.S. population lives in a county without a hospital that routinely treats eligible stroke victims with IV tPA. This, the second in a Missouri Medicine series on stroke, summarizes the available acute treatment options and the evolving role of neuro-imaging in directing therapeutic decisions.
authors.affiliation: University of Missouri-Kansas City School of Medicine, USA. mrymer@saint-lukes.org
authors.forename: Marilyn M
authors.initials: MM
authors.lastname: Rymner
authors.forename: Naveed
authors.initials: N
authors.lastname: Akhtar
authors.forename: Coleman
authors.initials: C
authors.lastname: Martin
authors.forename: Debbie
authors.initials: D
authors.lastname: Summers
mesh_terms: D000208:Acute Disease; D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy; D004333:Drug Administration Routes; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D015427:Reperfusion Injury / Q000517:prevention & control*; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator