title: Facial palsy and idiopathic intracranial hypertension in twins with cystic fibrosis and hypovitaminosis A.
abstract: Facial nerve palsies are uncommon in infants. We report on 10-week-old monozygotic twins, diagnosed with cystic fibrosis by newborn screening, who developed facial palsy and increased intracranial pressure. Cranial imaging and cerebrospinal fluid analysis produced normal results. Levels of serum vitamin A were below normal range. Low levels of vitamin A are associated with facial nerve paralysis, and are at least partly implicated in the development of increased intracranial pressure in infants with cystic fibrosis.
authors.affiliation: Division of Pediatric Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. mo2378@mail.cumc.columbia.edu
authors.forename: Makram
authors.initials: M
authors.lastname: Obeid
authors.forename: Jason
authors.initials: J
authors.lastname: Price
authors.forename: Linus
authors.initials: L
authors.lastname: Sun
authors.forename: Morris H
authors.initials: MH
authors.lastname: Scantlebury
authors.forename: Philip
authors.initials: P
authors.lastname: Overby
authors.forename: Reet
authors.initials: R
authors.lastname: Sidhu
authors.forename: Claudia A
authors.initials: CA
authors.lastname: Chiriboga
authors.forename: Lynne M
authors.initials: LM
authors.lastname: Quittell
mesh_terms: D003550:Cystic Fibrosis / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D004200:Diseases in Twins / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D005158:Facial Paralysis / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D011559:Pseudotumor Cerebri / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D014802:Vitamin A Deficiency / Q000150:complications / Q000175:diagnosis* / Q000235:genetics