title: Effect of zinc in tablet and suspension formulations in the treatment of acute diarrhoea among young children in an emergency setting of earthquake affected region of Pakistan.
abstract: A longitudinal cohort study was conducted at Camp Hospital Batagram in August 2006 to ascertain the effect of Zinc utilization in tablet and suspension formulations on the frequency and recovery rates of diarrhoea among young children in the emergency settings of earthquake affected region of Pakistan. Two hundred patients were recruited and followed up, the patients were allocated either of the 2 groups i.e. A (zinc in tablets form) and B (zinc in suspension form). Both groups also received WHO recommended treatment for diarrhoea. Most of the cases recovered from the illness within 3 days after presentation. Significant p-values were established among Zinc use and reduction in frequency of stools on Day 2 and 3, with better outcome in group B. The study supports the notion that zinc reduces the frequency and improves recovery rates of diarrhoea in any form and has better compliance and outcomes with the use in suspension form.
authors.affiliation: Department of Paediatrics, The Aga Khan University Hosptial, Karachi.
authors.forename: Muhammad Atif
authors.initials: MA
authors.lastname: Habib
authors.forename: Sajid Bashir
authors.initials: SB
authors.lastname: Soofi
authors.forename: Zulfiqar A
authors.initials: ZA
authors.lastname: Bhutta
mesh_terms: D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000188:drug therapy*; D004190:Disasters; D055866:Earthquakes; D006801:Humans; D007223:Infant; D010154:Pakistan; D013535:Suspensions; D013607:Tablets; D015032:Zinc / Q000008:administration & dosage*
chemical_list: D013535:Suspensions; D013607:Tablets; D015032:Zinc