title: Five carboxin-resistant mutants exhibited various responses to carboxin and related fungicides.
abstract: Five carboxin-resistant mutants from Aspergillus oryzae were characterized by the sensitivities of their mycelial growth and succinate dehydrogenase (SDH) activity to carboxin and three related fungicides. Despite a significant resistance to carboxin, exhibited by all the mutants, their patterns of sensitivity to the other fungicides was distinct. This provides clues to the molecular interaction between SDH and these fungicides.
authors.affiliation: Food Biotechnology Division, National Food Research Institute, National Agriculture and Food Research Organization, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Shima
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ito
authors.forename: Hidemi
authors.initials: H
authors.lastname: Hatabayashi
authors.forename: Akemi
authors.initials: A
authors.lastname: Koma
authors.forename: Kimiko
authors.initials: K
authors.lastname: Yabe
mesh_terms: D001236:Aspergillus oryzae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics*; D002261:Carboxin / Q000633:toxicity*; D025141:Drug Resistance, Fungal / Q000235:genetics*; D005659:Fungicides, Industrial / Q000633:toxicity*; D009154:Mutation; D025282:Mycelium / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D005659:Fungicides, Industrial; D002261:Carboxin; D013385:Succinate Dehydrogenase