title: CNV-WebStore: online CNV analysis, storage and interpretation.
abstract: BACKGROUND
  Microarray technology allows the analysis of genomic aberrations at an ever increasing resolution, making functional interpretation of these vast amounts of data the main bottleneck in routine implementation of high resolution array platforms, and emphasising the need for a centralised and easy to use CNV data management and interpretation system.
  
  
  RESULTS
  We present CNV-WebStore, an online platform to streamline the processing and downstream interpretation of microarray data in a clinical context, tailored towards but not limited to the Illumina BeadArray platform. Provided analysis tools include CNV analsyis, parent of origin and uniparental disomy detection. Interpretation tools include data visualisation, gene prioritisation, automated PubMed searching, linking data to several genome browsers and annotation of CNVs based on several public databases. Finally a module is provided for uniform reporting of results.
  
  
  CONCLUSIONS
  CNV-WebStore is able to present copy number data in an intuitive way to both lab technicians and clinicians, making it a useful tool in daily clinical practice.
authors.affiliation: Department of Medical Genetics, University Hospital Antwerp, Antwerp, Belgium.
authors.forename: Geert
authors.initials: G
authors.lastname: Vandeweyer
authors.forename: Edwin
authors.initials: E
authors.lastname: Reyniers
authors.forename: Wim
authors.initials: W
authors.lastname: Wuyts
authors.forename: Liesbeth
authors.initials: L
authors.lastname: Rooms
authors.forename: R Frank
authors.initials: RF
authors.lastname: Kooy
mesh_terms: D003628:Database Management Systems; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D020411:Oligonucleotide Array Sequence Analysis