title: [Successfully resected an isolated extraperitoneal metastasis of sigmoid colon cancer--a case report].
abstract: We herein report an extremely rare operative case of an isolated extraperitoneal metastasis of colon cancer. A female patient had undergone a sigmoidectomy for ileus due to sigmoid colon cancer when she was 40 years old. Peritoneal metastasis, 5 mm in diameter, was on the sigmoid colon mesentery and she was histologically diagnosed as Stage IV. She received fluorouracil-based adjuvant chemotherapy for 24 months. Serum CEA increased gradually from 36 months after the operation, and CT scan demonstrated bilateral ovarium tumors. Bilateral oophorectomy was performed at 44 months after the operation. Serum CEA decreased temporarily, but increased again. Serum CEA increased in spite of giving UFT/LV, so we changed to mFOLFOX6 therapy. Serum CEA decreased until it reached to a normal range after 9 courses, and stopped mFOLFOX6 therapy. Four months later, serum CEA increased again and PET-CT demonstrated a 3 cm mass with calcification in pelvic, and accumulation of FDP. Serum CEA decreased until it reached to a normal range after a resection of extraperitoneal mass. A histological examination of the tumor revealed a moderately differentiated adenocarcinoma similar to colon cancer. She has been well without recurrence 77 months after the first operation.
authors.affiliation: Dept. of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University.
authors.forename: Azusa
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Tajima
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hatano
authors.forename: Toru
authors.initials: T
authors.lastname: Ishiguro
authors.forename: Tomonori
authors.initials: T
authors.lastname: Osawa
authors.forename: Norimichi
authors.initials: N
authors.lastname: Okada
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kumamoto
authors.forename: Masaru
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Norihiro
authors.initials: N
authors.lastname: Haga
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery*; D002272:Carcinoembryonic Antigen / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D010052:Ovariectomy; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000556:secondary*; D012811:Sigmoid Neoplasms / Q000473:pathology* / Q000601:surgery*
chemical_list: D002272:Carcinoembryonic Antigen