title: Transition of endothelium to cartilage and bone.
abstract: Mesenchymal stromal cells (MSCs) are capable of differentiating into bone-forming osteoblasts. A recent Nature Medicine study (Medici et al., 2010) shows that the mislocalized bone in the human disease fibrodisplasia ossificans progressiva (FOP) originates from vascular endothelium that gives rise to MSCs.
authors.affiliation: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehvot 76100, Israel.
authors.forename: Ofer
authors.initials: O
authors.lastname: Shoshani
authors.forename: Dov
authors.initials: D
authors.lastname: Zipori