title: [A case of rectal carcinoid with multiple liver, lymph nodes and bone metastases that responded to an octreotide therapy].
abstract: A 45-year-old man was admitted to our hospital with a chief complaint of anal bleeding. Colonoscopy revealed a lower rectal tumor diagnosed as rectal carcinoid on biopsy. Multiple metastatic liver tumors were found on abdominal CT scan. We performed an abdomino-perineal resection, a partial hepatectomy, and TACE. There seemed to be no apparent residues of a carcinoid tumor on abdominal CT. About one year after the first therapy, CT scan had revealed multiple metastases to the liver, lymph nodes and bones. Therefore, we started an octreotide LAR, which remarkably reduced the size of metastatic tumors. The treatment of an octreotide LAR had controlled the progression of metastatic tumors for two and half years. In this case, the effect of an octreotide LAR for recurrence of rectal carcinoid after local therapies brought good controls of symptoms and an inhibition of tumor growth for long-term.
authors.affiliation: Division of Gastrointestinal Surgery, Dept. of Surgery, Kobe University, Graduate School of Medicine.
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Yamashita
authors.forename: Shiro
authors.initials: S
authors.lastname: Takase
authors.forename: Tetsu
authors.initials: T
authors.lastname: Nakamura
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Imanishi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sumi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Takashi
authors.initials: T
authors.lastname: Kamigaki
authors.forename: Yonson
authors.initials: Y
authors.lastname: Ku
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kuroda
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D002276:Carcinoid Tumor / Q000188:drug therapy* / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D015282:Octreotide / Q000627:therapeutic use*; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide