title: Low temperature capture of pseudorotaxanes.
abstract: Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh(3). The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.
authors.affiliation: EaStCHEM and Centre for Biomolecular Sciences, School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, Fife KY16 9ST, United Kingdom.
authors.forename: Nurul Izzaty
authors.initials: NI
authors.lastname: Hassan
authors.forename: Vicente
authors.initials: V
authors.lastname: del Amo
authors.forename: Ewen
authors.initials: E
authors.lastname: Calder
authors.forename: Douglas
authors.initials: D
authors.lastname: Philp
mesh_terms: D003080:Cold Temperature; D008958:Models, Molecular; D043862:Rotaxanes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D043862:Rotaxanes