title: Acute levetiracetam overdose presented with mild adverse events.
abstract: OBJECTIVE
  Overdose of levetiracetam may produce neurotoxicity.
  
  
  METHODS
  We reported a patient with epilepsy who took an overdose of 63 grams of levetiracetam with mild adverse events. The patient presented mild blurred vision and mild ataxia that rapidly subsided within one day with supportive care. The laboratory tests showed mild leucopenia and mild thrombocytopenia that gradually returned to normal within 2 months.
  
  
  CONCLUSIONS
  The pharmacokinetics, tolerability and adaptation of levetiracetam might play a role in the mild adverse events of levetiracetam overdose in our patient.
authors.affiliation: Department of Neurology, Kaiser Permanente Medical Center, Anaheim, California 92806, USA. siri.chayasirisobhon@kp.org
authors.forename: Sirichai
authors.initials: S
authors.lastname: Chayasirisobhon
authors.forename: Wuttichai V
authors.initials: WV
authors.lastname: Chayasirisobhon
authors.forename: Cassidy C
authors.initials: CC
authors.lastname: Tsay
mesh_terms: D000328:Adult; D006801:Humans; D000077287:Levetiracetam; D008297:Male; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D010889:Piracetam / Q000031:analogs & derivatives* / Q000506:poisoning; D012640:Seizures / Q000188:drug therapy
chemical_list: D000077287:Levetiracetam; D010889:Piracetam