title: Evaluation of one-sample testing of self-obtained vaginal swabs and first catch urine samples separately and in combination for the detection of Chlamydia trachomatis by two amplified DNA assays in women visiting a sexually transmitted disease clinic.
abstract: This study evaluates the performance of self-obtained vaginal swabs (SVS)/first-catch urine (FCU) combination samples in comparison to testing FCU or SVS alone. The Chlamydia trachomatis detection rate for the SVS, FCU, and SVS/FCU combination were 94%, 90%, and 94%, respectively. Self-obtained vaginal swabs are therefore the specimen of choice for Chlamydia trachomatis Nucleic Acid Amplification Tests in females.
authors.affiliation: Department of Medical Microbiology, Maastricht University Medical Centre, Maastricht, The Netherlands. Lauravandommelen@yahoo.com
authors.forename: Laura
authors.initials: L
authors.lastname: van Dommelen
authors.forename: Nicole
authors.initials: N
authors.lastname: Dukers-Muijrers
authors.forename: Frank H
authors.initials: FH
authors.lastname: van Tiel
authors.forename: Elfi E H G
authors.initials: EE
authors.lastname: Brouwers
authors.forename: Christian J P A
authors.initials: CJ
authors.lastname: Hoebe
mesh_terms: D000554:Ambulatory Care Facilities; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control / Q000652:urine; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D016133:Polymerase Chain Reaction; D012648:Self Care; D012680:Sensitivity and Specificity; D012749:Sexually Transmitted Diseases / Q000517:prevention & control; D013048:Specimen Handling / Q000379:methods*; D014556:Urine / Q000382:microbiology*; D014621:Vagina / Q000382:microbiology*