title: Peritoneal surface malignancies and regional treatment: a review of the literature.
abstract: Recent studies have lead to a renewed interest in cytoreductive surgery and intraperitoneal chemotherapy as a regional treatment modality for patients with peritoneal surface malignancies. There have been multiple phase III randomized trials that have shown a survival advantage with intraperitoneal chemotherapy in certain patients. More well designed phase III studies are needed to further define which groups of patients may benefit from cytoreductive surgery and intraperitoneal chemotherapy.
authors.affiliation: Department of Surgery, Helen F. Graham Cancer Center at Christiana Care, 4745 Ogletown-Stanton Road, Newark, DE 19713, USA. mrubino@christianacare.org
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Rubino
authors.forename: Raafat Z
authors.initials: RZ
authors.lastname: Abdel-Misih
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Bennett
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Petrelli
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000601:surgery; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery; D019990:Perioperative Care / Q000379:methods; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D011553:Pseudomyxoma Peritonei / Q000188:drug therapy / Q000601:surgery; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents