title: "Proof-of-principle" concept for label-free detection of glucose and α-glucosidase activity through the electrostatic assembly of alkynylplatinum(II) terpyridyl complexes.
abstract: A two-component platinum(II) complex-polymer ensemble has been demonstrated for label-free spectroscopic detection of glucose and α-glucosidase activity, based on the electrostatic assembly of cationic platinum(II) complex molecules onto a glucose-bound anionic polymer.
authors.affiliation: Institute of Molecular Functional Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.
authors.forename: Clive Yik-Sham
authors.initials: CY
authors.lastname: Chung
authors.forename: Kenneth Hoi-Yiu
authors.initials: KH
authors.lastname: Chan
authors.forename: Vivian Wing-Wah
authors.initials: VW
authors.lastname: Yam
mesh_terms: D001897:Boronic Acids / Q000737:chemistry; D005947:Glucose / Q000032:analysis*; D006009:Glycogen Storage Disease Type II / Q000175:diagnosis; D006801:Humans; D009944:Organoplatinum Compounds / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D012680:Sensitivity and Specificity; D013053:Spectrophotometry / Q000379:methods*; D055672:Static Electricity; D000520:alpha-Glucosidases / Q000378:metabolism*
chemical_list: D001897:Boronic Acids; D009944:Organoplatinum Compounds; D011725:Pyridines; D000520:alpha-Glucosidases; D005947:Glucose