title: [Comparison of clinicopathological characteristics between colorectal signet-ring cell carcinoma and mucinous adenocarcinoma].
abstract: OBJECTIVE
  To compare the difference of clinicopathological characteristics between colorectal signet-ring cell carcinoma and mucinous adenocarcinoma.
  
  
  METHODS
  The clinicopathological and survival data of 65 patients with colorectal signet-ring carcinoma and 166 with mucinous adenocarcinoma were retrospectively analyzed.
  
  
  RESULTS
  Such clinical characteristics as gender, gross anatomical classification, preoperative carcinoembryonic antigen level and hepatic metastasis or not had no significant difference between two groups (P > 0.05) while the difference of such characteristics as age, location of tumor, vascular tumor embolus, N stage, T stage, AJCC stage, preoperative obstruction and the ratio of radical resection between them was significant (P < 0.05). The overall 3, 5-year survival of the whole group was 56.7% and 31.6% respectively. The 3, 5-year survival and median survival time (MST) in the signet-ring cell carcinoma and the mucinous adenocarcinoma groups were 33.1%, 14.8%, 24.0 months and 64.1%, 36.6%, 41.5 months respectively. The pathological type of signet-ring cell carcinoma was an independent risk factor of survival in the whole group.
  
  
  CONCLUSIONS
  Compared to colorectal mucinous adenocarcinoma, signet-ring cell carcinoma has a higher degree of malignancy and the patients have a worse survival.
authors.affiliation: Department of Abdominal Surgical Oncology, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.forename: Cheng-feng
authors.initials: CF
authors.lastname: Wang
authors.forename: Dong-bing
authors.initials: DB
authors.lastname: Zhao
authors.forename: Ji-dong
authors.initials: JD
authors.lastname: Gao
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Bai
authors.forename: Yi-bin
authors.initials: YB
authors.lastname: Xie
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult