title: Synthesis of biaryl compounds using tandem ruthenium-catalyzed ring-closing metathesis.
abstract: Tandem ring-closing enyne metathesis (RCEM)/ring-closing olefin metathesis (RCM) of tetraenynes with Grubbs second-generation catalyst, followed by elimination, was found to be a new and efficient synthetic approach to biaryl compounds. A preliminary asymmetric version of this approach, which used homochiral Ru-alkylidene catalysts, is also presented.
authors.affiliation: Department of Chemistry, Graduate School of Science, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. kyoshida@faculty.chiba-u.jp
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shida
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Takahashi
authors.forename: Akira
authors.initials: A
authors.lastname: Yanagisawa