title: Histo- and cytoarchitectonics of the hippocampus in young rats injected with propofol and mexidol.
abstract: Light microscopic examination of the hippocampus was carried out in young rats (intact and injected with propofol and mexidol according to different protocols). Propofol had a negative effect on hippocampal neurons causing an almost 2-fold increase in the count of modified cells in comparison with the normal level. Mexidol effectively corrected these shifts.
authors.affiliation: N I Pirogov Russian State Medical University, Moscow, Russia. v@gusev.msk.su
authors.forename: T K
authors.initials: TK
authors.lastname: Dubovay
authors.forename: M A
authors.initials: MA
authors.lastname: Lobov
authors.forename: A A
authors.initials: AA
authors.lastname: Dreval
authors.forename: N R
authors.initials: NR
authors.lastname: Pashina
authors.forename: S S
authors.initials: SS
authors.lastname: Pashin
authors.forename: A V
authors.initials: AV
authors.lastname: Kuprin
authors.forename: S B
authors.initials: SB
authors.lastname: Bolevich
authors.forename: A V
authors.initials: AV
authors.lastname: Knazev
authors.forename: M V
authors.initials: MV
authors.lastname: Panteleeva
mesh_terms: D000777:Anesthetics / Q000009:adverse effects*; D000818:Animals; D006624:Hippocampus / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D009474:Neurons / Q000187:drug effects*; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010847:Picolines / Q000008:administration & dosage / Q000627:therapeutic use*; D015742:Propofol / Q000009:adverse effects*; D051381:Rats
chemical_list: D000777:Anesthetics; D018696:Neuroprotective Agents; D010847:Picolines; C070020:emoxypine succinate; D015742:Propofol