title: Glucose-lowering activity of novel tetrasaccharide glyceroglycolipids from the fruits of Cucurbita moschata.
abstract: Two new tetrasaccharide glyceroglycolipids were obtained from pumpkin. The structures of the two compounds were determined using chemical methods and spectroscopic analysis. Both compounds demonstrated significant glucose-lowering effects in streptozotocin- and high-fat-diet-induced diabetic mice.
authors.affiliation: Institute of Food and Biological Engineering, Zhejiang Gongshang University, Hangzhou, China.
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Jiang
authors.forename: Qizhen
authors.initials: Q
authors.lastname: Du
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D028464:Cucurbita / Q000737:chemistry*; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy; D005638:Fruit / Q000737:chemistry; D006017:Glycolipids / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation
chemical_list: D001786:Blood Glucose; D006017:Glycolipids; D007004:Hypoglycemic Agents; C557880:QGMG-2 compound; C557879:QGMG-3 compound