title: Effective treatment with hydroxychloroquine in a case of annular elastolytic giant cell granuloma.
abstract: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous and elastolytic skin disease of unknown pathogenesis. Therapy for AEGCG is controversial. The data about the effectiveness of chloroquine in the treatment of AEGCG are also variable. Here, we report a case of AEGCG with significant improvement after a total treatment period of 22 weeks with hydroxychloroquine. Although a possibility of spontaneous remission cannot be ruled out, we think that chloroquine can be considered as an effective treatment of this chronic disorder.
authors.affiliation: Department of Dermatology and Venereology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey. goncagulbabuna@yahoo.com
authors.forename: Goncagul
authors.initials: G
authors.lastname: Babuna
authors.forename: Nesimi
authors.initials: N
authors.lastname: Buyukbabani
authors.forename: K Didem
authors.initials: KD
authors.lastname: Yazganoglu
authors.forename: Can
authors.initials: C
authors.lastname: Baykal
mesh_terms: D000284:Administration, Oral; D001707:Biopsy, Needle; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D006886:Hydroxychloroquine / Q000008:administration & dosage*; D007150:Immunohistochemistry; D008875:Middle Aged; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D006886:Hydroxychloroquine