title: Uterus transplantation: on the edge.
abstract: Uterus transplantation for absolute uterus factor infertility is moving closer to human trials. The indication for uterus transplantation is evident as is its potential to ameliorate the social and personal burdens of these patients. The extensive collaborative research efforts between animal works, advancements in transplantation medicine, and immune suppression have culminated in demonstrating its apparent feasibility. As for the concerns regarding its risk, in perspective it is similar to other high-risk pregnancies. Moving uterus transplantation toward clinical applications obviously will require a continued commitment of research and support.
authors.affiliation: Indiana University, Simon Cancer Center, Department of Ob-Gyn, Indianapolis, Indiana 46202, USA. gdelprio@IUPIU.edu
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Del Priore
authors.forename: Stefan
authors.initials: S
authors.lastname: Schlatt
authors.forename: Robert
authors.initials: R
authors.lastname: Wagner
authors.forename: Elena
authors.initials: E
authors.lastname: Reynoso
authors.forename: Jeanetta
authors.initials: J
authors.lastname: Malanowska-Stega
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007165:Immunosuppression Therapy; D007247:Infertility, Female / Q000601:surgery; D008875:Middle Aged; D023421:Models, Animal; D011247:Pregnancy; D009927:Tissue and Organ Procurement; D014184:Transplantation, Homologous; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging / Q000637:transplantation*