title: The application of amorphous track models to study cell survival in heavy ions beams.
abstract: In a study of amorphous track models, in the local effect model (LEM), the Kellerer algorithm was used, which folds radial dose distributions from different ion tracks. In representative set of 10 experimental cell survival curves of normal human skin fibroblast cells irradiated with carbon ions, the method that applies the Kellerer algorithm was found to be more accurate and 10(4) times faster than the usual Monte Carlo summation method based on a regular grid.
authors.affiliation: Polish Academy of Science, Institute of Nuclear Physics, ul. Radzikowskiego 152, 31-342 Krakow, Poland.
authors.forename: L
authors.initials: L
authors.lastname: Grzanka
authors.forename: S
authors.initials: S
authors.lastname: Greilich
authors.forename: M
authors.initials: M
authors.lastname: Korcyl
authors.forename: O
authors.initials: O
authors.lastname: Jäkel
authors.forename: M
authors.initials: M
authors.lastname: Waligórski
authors.forename: P
authors.initials: P
authors.lastname: Olko
mesh_terms: D000465:Algorithms; D002470:Cell Survival / Q000528:radiation effects*; D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D020450:Heavy Ions; D018499:Linear Energy Transfer / Q000502:physiology*; D008954:Models, Biological; D011829:Radiation Dosage