title: Design and application of esterase-labile sulfonate protecting groups.
abstract: Three esterase-labile, but chemically-stable sulfonate protecting groups have been designed and synthesized. One of these sulfonate esters allowed the cytoplasmic delivery and unmasking of a sulfonated dye in live cells.
authors.affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation St., Worcester, MA 01605, USA.
authors.forename: Laert
authors.initials: L
authors.lastname: Rusha
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Miller
mesh_terms: D000476:Alkanesulfonates / Q000008:administration & dosage / Q000737:chemistry* / Q000378:metabolism*; D000818:Animals; D002463:Cell Membrane Permeability; D004396:Coloring Agents / Q000008:administration & dosage / Q000737:chemistry* / Q000378:metabolism*; D004950:Esterases / Q000378:metabolism*; D004952:Esters / Q000008:administration & dosage / Q000737:chemistry / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D013552:Swine
chemical_list: D000476:Alkanesulfonates; D004396:Coloring Agents; D004952:Esters; D004950:Esterases