title: Synthesis of CF3-substituted sulfoximines from sulfonimidoyl fluorides.
abstract: N-Protected trifluoromethyl-substituted sulfoximines have been prepared by treatment of sulfonimidoyl fluorides with a combination of the Ruppert-Prakash reagent (TMSCF(3)) and tetrabutyl ammonium fluoride (TBAF). The starting materials were accessed following two synthetic routes, and for each reaction sequence the substrate scope was evaluated. Accordingly, a wide variety of aryl-substituted products were obtained in moderate to good yield.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany.
authors.forename: Rafal
authors.initials: R
authors.lastname: Kowalczyk
authors.forename: Andrew J F
authors.initials: AJ
authors.lastname: Edmunds
authors.forename: Roger G
authors.initials: RG
authors.lastname: Hall
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm