title: Anti-melanoma differentiation-associated gene 5 antibody is a diagnostic and predictive marker for interstitial lung diseases associated with juvenile dermatomyositis.
abstract: The presence of the anti-melanoma differentiation-associated gene 5 antibody was evaluated in 13 patients with juvenile dermatomyositis (JDM). The antibody was positive in 5 of the 6 patients with JDM-associated interstitial lung disease (ILD), but not in the 7 patients without ILD. This antibody is a useful marker for early diagnosis of JDM-associated ILD.
authors.affiliation: Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan. ichikobaya@med.hokudai.ac.jp
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kobayashi
authors.forename: Yuka
authors.initials: Y
authors.lastname: Okura
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yamada
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Kawamura
authors.forename: Masataka
authors.initials: M
authors.lastname: Kuwana
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ariga
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D053487:DEAD-box RNA Helicases / Q000276:immunology*; D003882:Dermatomyositis / Q000150:complications / Q000276:immunology; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D000072640:Interferon-Induced Helicase, IFIH1; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000209:etiology* / Q000276:immunology; D008297:Male; D012189:Retrospective Studies
chemical_list: D000888:Antibodies, Anti-Idiotypic; D001323:Autoantibodies; C452815:IFIH1 protein, human; D053487:DEAD-box RNA Helicases; D000072640:Interferon-Induced Helicase, IFIH1