title: Cardiac mechanosensitivity and stretch-activated ion channels.
abstract: Mechanosensitivity is a ubiquitous property of cells, and mechanosensitive ion channels (MSCs) are hypothesized to be the transducers. In the heart, MSCs are likely to account for changes in beating rate as a function of filling and for initiating stretch-induced arrhythmias (for example, following a myocardial infarction). Pharmacological agents that affect MSCs may provide a new class of antiarrhythmic drugs. © 1997, Elsevier Science Inc. (Trends Cardiovasc Med 1997;7:4-8).
authors.affiliation: Department of Biophysical Sciences at State University of New York, Buffalo,NY 14214-3005,USA.
authors.forename: G C
authors.initials: GC
authors.lastname: Bett
authors.forename: F
authors.initials: F
authors.lastname: Sachs