title: [Phloroglucinol: safe and effective for the prevention of bladder spasm after TURP].
abstract: OBJECTIVE
  To evaluate the efficacy of phloroglucinol in preventing bladder spasm after transurethral resection of the prostate (TURP).
  
  
  METHODS
  Using the random sampling method, we assigned 74 cases of TURP into a treatment group (n = 39), given 80 mg phloroglucinol every day for 3 days, and a control group (n = 35), left untreated. Then we observed the frequency, duration and pain of bladder spasm within the 3 days and compared them between the two groups.
  
  
  RESULTS
  The mean frequency, duration and pain visual analogue score of bladder spasm were (4.3 +/- 1.2) times, (7.2 +/- 2.1) min and 3.2 +/- 1.6 respectively in the treatment group, as compared with (7.5 +/- 2.4) times, (15.6 +/- 6.8) min and 4.7 +/- 2.3 in the control, with statistically significant differences between the two groups (P < 0.05). And no obvious adverse reactions were found in the treatment group.
  
  
  CONCLUSIONS
  Phloroglucinol is safe and effective for the prevention and treatment of bladder spasm following TURP.
authors.affiliation: Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. chentd1983@163.com
authors.forename: Tie-Ding
authors.initials: TD
authors.lastname: Chen
authors.forename: Yin-Huai
authors.initials: YH
authors.lastname: Wang
authors.forename: Luo-Yan
authors.initials: LY
authors.lastname: Yang
authors.forename: Peng
authors.initials: P
authors.lastname: Jin
authors.forename: Jun-Bin
authors.initials: JB
authors.lastname: Yuan
authors.forename: Sheng-Peng
authors.initials: SP
authors.lastname: Wu
authors.forename: Song-Chao
authors.initials: SC
authors.lastname: Li
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D010696:Phloroglucinol / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D020728:Transurethral Resection of Prostate / Q000009:adverse effects; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000517:prevention & control*
chemical_list: D010696:Phloroglucinol