title: Human growth hormone and the development of osteochondritis dissecans lesions.
abstract: No single etiology regarding the cause of osteochondritis dissecans (OCD) lesions is unanimously accepted. This report documents a novel case of multiple OCD lesions affecting the left knee and a solitary defect of the right elbow in a patient with acquired human growth hormone (hGH) deficiency and supplementation. hGH deficiency and hormone replacement may be related to the development of OCD lesions.
authors.affiliation: Department of Surgery, Section of Orthopaedic Surgery & Rehabilitation Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, MC-3079, Chicago, IL 60637, USA. waqas.hussain@uchospitals.edu
authors.forename: Waqas M
authors.initials: WM
authors.lastname: Hussain
authors.forename: Haroon M
authors.initials: HM
authors.lastname: Hussain
authors.forename: Mohammed S
authors.initials: MS
authors.lastname: Hussain
authors.forename: Sherwin S W
authors.initials: SS
authors.lastname: Ho
mesh_terms: D000058:Accidental Falls; D000293:Adolescent; D001484:Baseball / Q000293:injuries; D004551:Elbow Joint / Q000601:surgery; D019382:Human Growth Hormone / Q000009:adverse effects* / Q000172:deficiency; D006801:Humans; D007718:Knee Injuries / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D007719:Knee Joint / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D010008:Osteochondritis Dissecans / Q000139:chemically induced* / Q000601:surgery
chemical_list: D019382:Human Growth Hormone