title: IgA antibodies to Chlamydia trachomatis and metabolic syndrome.
abstract: Chlamydia pneumoniae may trigger atherogenesis. Chlamydia trachomatis (CT) can also induce endothelial activation. However, its role in metabolic syndrome (METS), a proatherogenic entity, has remained unexplored. In this study the frequencies of IgA and IgG anti-CT antibodies were evaluated by immunoenzymatic assay in METS patients and healthy controls. The survey included 238 individuals (148 with METS). The mean age was 59.7 years. IgA anti-CT antibodies were found significantly more frequently in METS patients (16.9%) than in controls (5.6%) (P= 0.015). The role of such IgA response in METS should be further investigated.
authors.affiliation: Department of Nursing and Dentistry, University of Santa Cruz do Sul, Brazil. lucielesehnem@unisc.br
authors.forename: Luciele
authors.initials: L
authors.lastname: Sehnem
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Bodanese
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Repetto
authors.forename: Henrique L
authors.initials: HL
authors.lastname: Staub
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D002692:Chlamydia trachomatis / Q000276:immunology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology / Q000382:microbiology*; D008875:Middle Aged
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A