title: Halogenated POPs and PAHs in blood plasma of Hong Kong residents.
abstract: The objective of this study was to quantify organic chlorinated pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and polycyclic aromatic hydrocarbons (PAHs) in blood plasma collected from 111 healthy residents in Hong Kong to assess the levels of these pollutants in the general population during the period of March to April, 2008. Concentrations of these residues in blood plasma obtained from the Hong Kong Red Cross Blood Transfusion Service were determined by gas chromatography-mass spectrometry. Naphthalene, phenanthrene, p,p'-DDE, PCB-180, and PBDE-47 were detected in 100% of the participants. Females had significantly greater concentrations of acenaphthylene (female: 93.3 ng/g lipid; male: 39.8, p < 0.05), anthracene (22.3; 15.3, p < 0.05), fluoranthene (138; 125, p < 0.05), p,p'-DDE, p,p'-DDT, PCB-183, BDE-99 than males. Blood of smokers contained significantly greater (p < 0.05) concentrations of acenaphthene, benzo(a)pyrene, p,p'-DDE, p,p'-DDT, PCB-138, BDE-47, and BDE-99 than did blood of nonsmokers. Positive correlations were found between concentrations of each class of pollutant, with respect to seafood diet habit, Body Mass Index (BMI), and age. Concentrations of HCHs and DDTs in blood plasma of healthy Hong Kong residents were greater than those of other countries, and it was found that smoking, consumption of a seafood diet, BMI, and age could influence concentrations in human blood.
authors.affiliation: Croucher Institute for Environmental Sciences, and Department of Biology, Hong Kong Baptist University, Hong Kong, PR China.
authors.forename: Yan Yan
authors.initials: YY
authors.lastname: Qin
authors.forename: Clement K M
authors.initials: CK
authors.lastname: Leung
authors.forename: C K
authors.initials: CK
authors.lastname: Lin
authors.forename: Anna O W
authors.initials: AO
authors.lastname: Leung
authors.forename: Hong Sheng
authors.initials: HS
authors.lastname: Wang
authors.forename: John P
authors.initials: JP
authors.lastname: Giesy
authors.forename: Ming H
authors.initials: MH
authors.lastname: Wong
mesh_terms: D000328:Adult; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D006723:Hong Kong; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000097:blood; D008297:Male; D008875:Middle Aged; D010575:Pesticides / Q000032:analysis / Q000097:blood*; D011078:Polychlorinated Biphenyls / Q000097:blood*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis / Q000097:blood*; D017747:Seafood; D012907:Smoking; D055815:Young Adult
chemical_list: D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D011084:Polycyclic Aromatic Hydrocarbons; D011078:Polychlorinated Biphenyls