title: KPC-2 carbapenemase-producing Klebsiella pneumoniae isolates from patients with Cystic Fibrosis.
abstract: Bacteria producing Klebsiella pneumoniae carbapenemases (KPCs) are rapidly emerging as a cause of multidrug-resistant infections worldwide. KPCs enzyme are plasmid-borne and can accumulate and transfer resistance determinants to other classes of antibiotics.We report two cases of KPC-2 carbapenemase-producing Klebsiella pneumoniae isolates from Cystic Fibrosis patients.
authors.affiliation: Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Brazil.
authors.forename: Robson S
authors.initials: RS
authors.lastname: Leão
authors.forename: Rosana H V
authors.initials: RH
authors.lastname: Pereira
authors.forename: Tânia W
authors.initials: TW
authors.lastname: Folescu
authors.forename: Rodolpho M
authors.initials: RM
authors.lastname: Albano
authors.forename: Erica A
authors.initials: EA
authors.lastname: Santos
authors.forename: Luiz G C
authors.initials: LG
authors.lastname: Junior
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Marques
mesh_terms: D000293:Adolescent; D001426:Bacterial Proteins / Q000378:metabolism*; D003550:Cystic Fibrosis / Q000382:microbiology*; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000302:isolation & purification; D055815:Young Adult; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C547585:beta-lactamase KPC-2, Klebsiella pneumoniae; C531581:carbapenemase-2, Klebsiella pneumoniae