title: Oral candidiasis mimicking tongue cancer.
abstract: Candida species inhabit the mucosal surfaces of healthy individuals. Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen. We encountered a nodule caused by candidal infection on a forearm flap in the oral cavity mimicking a recurrent tongue cancer, which revealed as CHC by histopathological examination. Like other forms of oral candidiasis, the nodule well responded to the treatment of antifungal agents and eventually disappeared. When an intraoral nodule is observed, the possibility of CHC should be taken into consideration.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kobe University Hospital, Japan. tshibata-kob@umin.ac.jp
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Shibata
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yamashita
authors.forename: Shingo
authors.initials: S
authors.lastname: Hasegawa
authors.forename: Miki
authors.initials: M
authors.lastname: Saito
authors.forename: Naoki
authors.initials: N
authors.lastname: Otsuki
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Hashikawa
authors.forename: Shinya
authors.initials: S
authors.lastname: Tahara
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Nibu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D002180:Candidiasis, Oral / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D002945:Cisplatin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D005927:Glossectomy; D006801:Humans; D008297:Male; D037981:Neck Dissection; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology; D013524:Surgical Flaps; D014057:Tomography, X-Ray Computed; D014059:Tongue / Q000473:pathology; D014062:Tongue Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*
chemical_list: D002945:Cisplatin; D005472:Fluorouracil