title: Environmentally responsive threading, dethreading, and fixation of anion-induced pseudorotaxanes.
abstract: The tetracationic macrocycle cyclo[2](2,6-di(1H-imidazol-1-yl)pyridine)[2](1,4-dimethylenebenzene) hexafluorophosphate (1(4+)·4PF(6)(-)) acts as a large, flexible "molecular box" that supports the formation of environmentally responsive anion-induced pseudorotaxanes, as well as other extended structures, including metal-linked supramolecular polyrotaxanes. Specifically, the combination of the tetracation 1(4+) and bis-carboxylate guests derived from 4,4'-biphenyldicarboxylic acid and 2,6-naphthalenedicarboxylic acid results in the formation of pseudorotaxanes that respond to changes in environmental stimuli, including pH and temperature. The resulting structures can be "locked into place" via the addition of a metal-linker in the form of Ag(I); this gives rise to an ordered metal-linked polyrotaxane. The interpenetrated constructs described in this article were characterized in solution and in the solid state by one- and two-dimensional ((1)H and NOESY) NMR spectroscopy, as well as by mass spectrometry (ESI-MS) and single-crystal X-ray diffraction methods.
authors.affiliation: Department of Chemistry & Biochemistry, The University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-0165, United States.
authors.forename: Han-Yuan
authors.initials: HY
authors.lastname: Gong
authors.forename: Brett M
authors.initials: BM
authors.lastname: Rambo
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Karnas
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Lynch
authors.forename: Karin M
authors.initials: KM
authors.lastname: Keller
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Sessler