title: Unilateral proptosis in a 60-year-old man.
abstract: A 60-year-old immunocompromised patient developed rapidly progressive proptosis that was secondary to mucormycosis. This life-threatening fungal infection usually is associated with chemosis, proptosis, ophthalmoplegia, and visual loss. The fungus may invade ocular structures, sinuses, and extend into the brain. The standard of care includes correction of the underlying condition, administration of liposomal amphotericin B with posaconazole, and surgical debridement of infected and necrotic tissue. We present a case of unilateral proptosis due to mucormycosis in an immunocompromised patient. The patient was successfully managed medically without exenteration. The indications for exenteration are currently unclear, and no clinical guidelines exist.
authors.affiliation: Department of Ophthalmology, American University of Beirut-Medical Center, Lebanon.
authors.forename: Carole G
authors.initials: CG
authors.lastname: Cherfan
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Mansour
authors.forename: Muhammad H
authors.initials: MH
authors.lastname: Younis
authors.forename: Bobby S
authors.initials: BS
authors.lastname: Korn
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003646:Debridement; D015521:Ethmoid Sinusitis / Q000188:drug therapy / Q000382:microbiology*; D005094:Exophthalmos / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008232:Lymphoproliferative Disorders / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B