title: [Study on in vitro release and transdermal behaviors of mumps cataplasm of complex prescription].
abstract: OBJECTIVE
  To investigate the in vitro release and transdermal behaviors of mumps cataplasm of complex prescription.
  
  
  METHODS
  The improved Franz difficusion was used and the concentration of drugs was detected. DCS was determined by HPLC and flavanoid contents were determined by UV.
  
  
  RESULTS
  The accumulation skin permeation percentage of DCS and flavanoid was 32% and 21%, respectively, the in vitro release percentage of DCS and flavanoid was 47% and 42%, respectively.
  
  
  CONCLUSIONS
  The transdermal behavior of mumps cataplasm of complex prescription is an zero-order kinetics progress. The in vitro release behavior is in accordance with the Higuchi equation.
authors.affiliation: Department of pharmacology, Xi'an Jiaotong University, Xi'an 710061, China. songjinyan.524@stu.xjtu.edu.cn
authors.forename: Jin-yan
authors.initials: JY
authors.lastname: Song
authors.forename: Zeng-jun
authors.initials: ZJ
authors.lastname: Guo
authors.forename: Na
authors.initials: N
authors.lastname: Zheng
authors.forename: Nan
authors.initials: N
authors.lastname: Wu
authors.forename: Jun-jun
authors.initials: JJ
authors.lastname: Mao
authors.forename: Xiao-ming
authors.initials: XM
authors.lastname: Pang
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid; D004008:Diclofenac / Q000008:administration & dosage* / Q000032:analysis / Q000493:pharmacokinetics; D004338:Drug Combinations; D005419:Flavonoids / Q000032:analysis / Q000493:pharmacokinetics; D051379:Mice; D009107:Mumps / Q000188:drug therapy; D029747:Opuntia / Q000737:chemistry*; D010936:Plant Extracts / Q000008:administration & dosage* / Q000493:pharmacokinetics; D012867:Skin / Q000378:metabolism*; D012869:Skin Absorption; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D000998:Antiviral Agents; D004338:Drug Combinations; D005419:Flavonoids; D010936:Plant Extracts; D004008:Diclofenac