title: Electrophysiological characteristics of idiopathic ventricular tachycardia in children.
abstract: BACKGROUND
  Idiopathic ventricular tachycardia (VT) has been reported to have a good prognosis, but there still might be the potential risk of sudden death.
  
  
  RESULTS
  The 46 consecutive children (mean age 11.7 ± 3.4 years) with idiopathic VT were enrolled in this study. Monomorphic VT was detected in 39 patients and polymorphic VT in 7 patients. The VT originated from the right ventricle (RV) in 22 patients, and left ventricle (LV) in 17 patients. The VT was induced by exercise in 68% of the RVVT, 41% of the LVVT, and 100% of the polymorphic VT. The VT was induced by programmed ventricular stimulation in 41% of the RVVT, 35% of the LVVT, and none of the polymorphic VT. Adenosine tri-phosphate terminated the VT in 9 of 15 patients (60%). The mechanism of the VT was suspected to be triggered by activity in 36.4%, automaticity in 40.9%, and re-entry in 22.7% of the RVVT, whereas it was 52.9%, 5.9%, and 41.2% of the LVVT, respectively.
  
  
  CONCLUSIONS
  The exercise inducibility was higher in polymorphic VT than the RVVT and LVVT, but no difference in the programmed stimulation. The sensitivity to adenosine tri-phosphate was not different between the RVVT and LVVT. In some patients with idiopathic VT, a non-verapamil sensitive re-entry was documented, which was more common in patients with ischemic heart disease or cardiomyopathy.
authors.affiliation: Department of Pediatrics and Child Health, Nihon University, School of Medicine, Tokyo, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Fukuhara
authors.forename: Naokata
authors.initials: N
authors.lastname: Sumitomo
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakamura
authors.forename: Rie
authors.initials: R
authors.lastname: Ichikawa
authors.forename: Masaharu
authors.initials: M
authors.lastname: Matsumura
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.forename: Michio
authors.initials: M
authors.lastname: Miyashita
authors.forename: Kazuo
authors.initials: K
authors.lastname: Taniguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kanamaru
authors.forename: Mamoru
authors.initials: M
authors.lastname: Ayusawa
authors.forename: Kensuke
authors.initials: K
authors.lastname: Karasawa
authors.forename: Hideo
authors.initials: H
authors.lastname: Mugishima
mesh_terms: D000293:Adolescent; D017115:Catheter Ablation; D002648:Child; D002675:Child, Preschool; D022062:Electrophysiologic Techniques, Cardiac; D055724:Electrophysiological Phenomena / Q000502:physiology*; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D017180:Tachycardia, Ventricular / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*; D018497:Ventricular Dysfunction, Right / Q000503:physiopathology*; D055815:Young Adult