title: [The changes of density of platelet glycoprotein (GP) II b/III a receptor in the perioperative period of gastrectomy in aged rats].
abstract: OBJECTIVE
  To investigate changes of density of platelet glycoprotein (GP) II b/III a receptor in the perioperative period of gastrectomy in aged rats.
  
  
  METHODS
  The subtotal gastrectomy operation was performed in 16 adult rats and 16 aged rats respectively. Platelet surface density of GP II b/III receptors were determined by flow cytometric analysis before and 6, 12, 24, 48, 72 hours after operation.
  
  
  RESULTS
  6, 12, 24, 48 and 72 hours after operation, the density of GP II b/III a in aged group increased continuously compared with preoperative period (6h, 12, 72: P < 0.05; 24, 48: P < 0.01).
  
  
  CONCLUSIONS
  Gastrectomy can lead to an increase of density of platelet GP II b/III a receptor in aged rats.
authors.affiliation: The Institute of Geriatric Cardiology, The General Hospital of PLA, Beijing 100853, China.
authors.forename: Y F
authors.initials: YF
authors.lastname: Li
authors.forename: S W
authors.initials: SW
authors.lastname: Wang
authors.forename: Y S
authors.initials: YS
authors.lastname: Zhao
authors.forename: L L
authors.initials: LL
authors.lastname: Liu
authors.forename: M Y
authors.initials: MY
authors.lastname: Chen
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: B
authors.initials: B
authors.lastname: Feng
authors.forename: S T
authors.initials: ST
authors.lastname: Yu
mesh_terms: D000375:Aging; D000818:Animals; D005743:Gastrectomy; D039661:Integrin beta3 / Q000378:metabolism*; D059035:Perioperative Period; D040201:Platelet Membrane Glycoprotein IIb / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D039661:Integrin beta3; D040201:Platelet Membrane Glycoprotein IIb