title: Phylogeography of Francisella tularensis ssp. holarctica in France.
abstract: OBJECTIVE
  To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.
  
  
  RESULTS
  Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.
  
  
  CONCLUSIONS
  The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.
  
  
  CONCLUSIONS
  This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.
authors.affiliation: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Vogler
authors.forename: D N
authors.initials: DN
authors.lastname: Birdsell
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: J
authors.initials: J
authors.lastname: Vaissaire
authors.forename: C L
authors.initials: CL
authors.lastname: Doujet
authors.forename: M
authors.initials: M
authors.lastname: Lapalus
authors.forename: D M
authors.initials: DM
authors.lastname: Wagner
authors.forename: P
authors.initials: P
authors.lastname: Keim
mesh_terms: D005602:France; D005604:Francisella tularensis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D005838:Genotype; D018598:Minisatellite Repeats; D010802:Phylogeny; D058974:Phylogeography; D020641:Polymorphism, Single Nucleotide