title: Expression of utrophin at dystrophin-deficient neuromuscular synapses of mdx mice: a study of protected and affected muscles.
abstract: In mdx mice, intrinsic laryngeal muscles are spared and sternomastoid muscles are affected, showing cycles of muscle regeneration. We observed that utrophin and acetylcholine receptors are fragmented only in affected muscles, providing further evidence that changes in the overall distribution of molecules at dystrophic neuromuscular junctions may be correlated with muscle regeneration.
authors.affiliation: Department of Anatomy, Cell Biology, Physiology and Biophysics, Institute of Biology, State University of Campinas (UNICAMP), Campinas, São Paulo 13083-970, Brazil.
authors.forename: Renato
authors.initials: R
authors.lastname: Ferretti
authors.forename: Humberto Santo
authors.initials: HS
authors.lastname: Neto
authors.forename: Maria Julia
authors.initials: MJ
authors.lastname: Marques
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D016189:Dystrophin / Q000172:deficiency*; D007821:Laryngeal Muscles / Q000294:innervation / Q000378:metabolism / Q000473:pathology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018101:Mice, Inbred mdx / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000294:innervation / Q000378:metabolism* / Q000473:pathology; D020388:Muscular Dystrophy, Duchenne / Q000378:metabolism* / Q000473:pathology; D009334:Neck Muscles / Q000294:innervation / Q000378:metabolism / Q000473:pathology; D009469:Neuromuscular Junction / Q000378:metabolism*; D011950:Receptors, Cholinergic / Q000378:metabolism; D012038:Regeneration / Q000502:physiology; D013569:Synapses / Q000378:metabolism*; D049411:Utrophin / Q000378:metabolism*
chemical_list: D016189:Dystrophin; D011950:Receptors, Cholinergic; D049411:Utrophin