title: A case of cervical cancer-related membranous nephropathy treated with radiation therapy.
abstract: Paraneoplastic nephropathy is a rare complication of malignant disease. We present a case of cervical cancer with biopsy-proven membranous nephropathy and associated nephrotic syndrome. Irradiation to the specific neoplasm site and to the metastatic paraaortic lymph node tissues lead to regression of the nephrotic syndrome without causing severe adverse events. Radiation therapy can be the first choice in the treatment of paraneoplastic nephrotic syndrome if the primary neoplasm is unresectable. Invasiveness of intervention and patient prognosis should be carefully deliberated in the management of the two diseases.
authors.affiliation: Division of Nephrology, Department of Medicine, Jichi Medical School, Japan. ichiharu@jichi.ac.jp
authors.forename: Chiharu
authors.initials: C
authors.lastname: Ito
authors.forename: Tetsu
authors.initials: T
authors.lastname: Akimoto
authors.forename: Eiko
authors.initials: E
authors.lastname: Nakazawa
authors.forename: Satoko
authors.initials: S
authors.lastname: Komori
authors.forename: Taro
authors.initials: T
authors.lastname: Sugase
authors.forename: Junko
authors.initials: J
authors.lastname: Chinda
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Ioka
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Muto
authors.forename: Eiji
authors.initials: E
authors.lastname: Kusano
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000532:radiotherapy; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D009404:Nephrotic Syndrome / Q000209:etiology / Q000532:radiotherapy; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000532:radiotherapy*; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000532:radiotherapy