title: Rates of new neurological deficit associated with spine surgery based on 108,419 procedures: a report of the scoliosis research society morbidity and mortality committee.
abstract: METHODS
  Retrospective review of a prospectively collected, multicenter database.
  
  
  OBJECTIVE
  To assess rates of new neurologic deficit (NND) associated with spine surgery.
  
  
  BACKGROUND
  NND is a potential complication of spine surgery, but previously reported rates are often limited by small sample size and single-surgeon experiences.
  
  
  METHODS
  The Scoliosis Research Society morbidity and mortality database was queried for spinal surgery cases complicated by NND from 2004 to 2007, including nerve root deficit (NRD), cauda equina deficit (CED), and spinal cord deficit (SCD). Use of neuromonitoring was assessed. Recovery was stratified as complete, partial, or none. Rates of NND were stratified based on diagnosis, age (pediatric < 21; adult ≥ 21), and surgical parameters.
  
  
  RESULTS
  Of the 108,419 cases reported, NND was documented for 1064 (1.0%), including 662 NRDs, 74 CEDs, and 293 SCDs (deficit not specified for 35 cases). Rates of NND were calculated on the basis of diagnosis. Revision cases had a 41% higher rate of NND (1.25%) compared with primary cases (0.89%; P < 0.001). Pediatric cases had a 59% higher rate of NND (1.32%) compared with adult cases (0.83%; P < 0.001). The rate of NND for cases with implants was more than twice that for cases without implants (1.15% vs. 0.52%, P < 0.001). Neuromonitoring was used for 65% of cases, and for cases with new NRD, CED, and SCD, changes in neuromonitoring were reported in 11%, 8%, and 40%, respectively. The respective percentages of no recovery, partial, and complete recovery for NRD were 4.7%, 46.8%, and 47.1%, respectively; for CED were 9.6%, 45.2%, and 45.2%, respectively; and for SCD were 10.6%, 43%, and 45.7%, respectively.
  
  
  CONCLUSIONS
  Our data demonstrate that, even among skilled spinal deformity surgeons, new neurologic deficits are inherent potential complications of spine surgery. These data provide general benchmark rates for NND with spine surgery as a basis for patient counseling and for ongoing efforts to improve safety of care.
authors.affiliation: University of Maryland, School of Medicine, Department of Neurological Surgery, Baltimore, MD, USA.
authors.forename: D Kojo
authors.initials: DK
authors.lastname: Hamilton
authors.forename: Justin S
authors.initials: JS
authors.lastname: Smith
authors.forename: Charles A
authors.initials: CA
authors.lastname: Sansur
authors.forename: Steven D
authors.initials: SD
authors.lastname: Glassman
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Ames
authors.forename: Sigurd H
authors.initials: SH
authors.lastname: Berven
authors.forename: David W
authors.initials: DW
authors.lastname: Polly
authors.forename: Joseph H
authors.initials: JH
authors.lastname: Perra
authors.forename: Dennis Raymond
authors.initials: DR
authors.lastname: Knapp
authors.forename: Oheneba
authors.initials: O
authors.lastname: Boachie-Adjei
authors.forename: Richard E
authors.initials: RE
authors.lastname: McCarthy
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Shaffrey
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D035843:Biomedical Research / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology*; D019637:Orthopedic Procedures / Q000009:adverse effects* / Q000379:methods / Q000706:statistics & numerical data; D011128:Polyradiculopathy / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology*; D011843:Radiculopathy / Q000209:etiology; D012600:Scoliosis / Q000401:mortality / Q000601:surgery; D012955:Societies, Medical; D013118:Spinal Cord Diseases / Q000209:etiology; D013122:Spinal Diseases / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate; D055815:Young Adult