title: Isoflavones from the mangrove endophytic fungus Fusarium sp. (ZZF41).
abstract: A new isoflavone, 5-O-methyl-2'-methoxy-3'-methylalpinumisoflavone (1), together with four known compounds 6-methoxy-5,7,4'-trihydroxyisoflavone (2), 6-methoxy-7,4'-dihydroxyisoflavone (3), (+)-marmesin (4), and 4-methylbenzoic acid carboxymethyl ester (5), were isolated from the mangrove endophytic fungus, Fusarium sp. (ZZF41). Their structures were determined by analysis of spectroscopic data. Compound 1 inhibited HEp-2 and HepG2 cells with IC50 values of 4 and 11 micromol/mL, respectively.
authors.affiliation: College of Chemistry and Ecology Engineering, Guangxi University for Nationalities, Nanning, 530006 Guangxi Proxince, People's Republic of China. zhongjinghuang@yahoo.cn
authors.forename: Zhongjing
authors.initials: Z
authors.lastname: Huang
authors.forename: Jianxiang
authors.initials: J
authors.lastname: Yang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: She
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Lin
mesh_terms: D002460:Cell Line; D005670:Fusarium / Q000737:chemistry* / Q000145:classification*; D006801:Humans; D007529:Isoflavones / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D007529:Isoflavones