title: Presumed cytomegalovirus retinitis in human immunodeficiency virus type I-infected South African children.
abstract: In human immunodeficiency virus-infected children, cytomegalovirus causes retinitis alone, with dissemination, or with immune reconstitution inflammatory syndrome. We describe 6 severely immunosuppressed African children (median age, 6.7 months) with cytomegalovirus disease. Of the 6 children, 5 had clinical features suggesting ocular disease at presentation. The child in whom retinitis was detected through preemptive screening due to systemic disease achieved normal visual outcome.
authors.affiliation: Department of Paediatrics and Child Health, Tygerberg Children's Hospital, Stellenbosch University, Cape Town, South Africa. tashoconnell@gmail.com
authors.forename: Natasha
authors.initials: N
authors.lastname: O'connell
authors.forename: Nicola
authors.initials: N
authors.lastname: Freeman
authors.forename: Helena
authors.initials: H
authors.lastname: Rabie
authors.forename: Mark F
authors.initials: MF
authors.lastname: Cotton
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000821:virology; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000302:isolation & purification; D017726:Cytomegalovirus Retinitis / Q000175:diagnosis* / Q000821:virology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008297:Male; D013019:South Africa