title: Short report: Human Trichostrongylus colubriformis infection in a rural village in Laos.
abstract: In Lahanam Village, Savannakhet Province, Laos, 125 of 253 villagers (49.4%) were found by fecal examination to harbor hookworm eggs. The eggs were heterogeneous in morphology and size, suggesting infections of mixed nematode species. To confirm the hookworm egg species, on a voluntary basis, 46 hookworm egg-positive participants were treated with albendazole, and post-treatment adult worms were collected from purged fecal samples. The common human hookworm was found in only 3 participants; 1 case of Necator americanus, and 2 cases of Ancylostoma duodenale. In contrast, adult Trichostrongylus worms were expelled from most participants (43 of 46, 93.5%). The Trichostrongylus species were confirmed by morphology and internal transcribed spacer 2 sequences; all worms were of the same species (T. colubriformis). In addition, some Trichostrongylus worms were obtained from a goat in the same village and identified as T. colubriformis. The results suggested that T. colubriformis was the main zoonotic species causing hookworm infections in the village.
authors.affiliation: Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. mi_197439@hotmail.com
authors.forename: Megumi
authors.initials: M
authors.lastname: Sato
authors.forename: Tippayarat
authors.initials: T
authors.lastname: Yoonuan
authors.forename: Surapol
authors.initials: S
authors.lastname: Sanguankiat
authors.forename: Supaporn
authors.initials: S
authors.lastname: Nuamtanong
authors.forename: Tiengkham
authors.initials: T
authors.lastname: Pongvongsa
authors.forename: Inthava
authors.initials: I
authors.lastname: Phimmayoi
authors.forename: Vilayphone
authors.initials: V
authors.lastname: Phanhanan
authors.forename: Boungnong
authors.initials: B
authors.lastname: Boupha
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Moji
authors.forename: Jitra
authors.initials: J
authors.lastname: Waikagul
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D005260:Female; D015511:Goat Diseases / Q000469:parasitology; D006041:Goats; D006801:Humans; D007812:Laos / Q000453:epidemiology; D008297:Male; D010802:Phylogeny; D012424:Rural Population; D014253:Trichostrongylosis / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology; D014254:Trichostrongylus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D000871:Anthelmintics; D015766:Albendazole