title: [Advanced research in Sclera collagen cross-linking treating progressive myopia].
abstract: Collagen can link between or within collagen molecules through the covalent bond, which leads to increasing the tension and stability of collagen fiber. Collagen cross-linking had been widely used in other industries, the recent research showed that cross-linking of scleral collagen increased the scleral biomechanical rigidity efficiently, which might become a new treatment modality for strengthening scleral tissue to prevent progressive myopia. This review describes the sclera collagen characteristics of progressive myopia, traditional treatment and sclera collagen cross-linking therapy.
authors.affiliation: Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100730, China.
authors.forename: Yan-yan
authors.initials: YY
authors.lastname: Zhao
authors.forename: Hong-hong
authors.initials: HH
authors.lastname: Zhao
authors.forename: Feng-ju
authors.initials: FJ
authors.lastname: Zhang
mesh_terms: D003094:Collagen / Q000627:therapeutic use*; D003432:Cross-Linking Reagents / Q000627:therapeutic use*; D006801:Humans; D009216:Myopia / Q000188:drug therapy*; D012590:Sclera
chemical_list: D003432:Cross-Linking Reagents; D003094:Collagen