title: Primary diffuse large B-cell lymphoma of the skull mimicking osteomyelitis.
abstract: Primary lymphomas of the skull are extremely rare, as fewer than 20 cases have been reported in the literature. We describe the case of a 51-year-old woman with Huntington chorea who presented with forehead swelling. Imaging studies detected an enhancing mass in the skull with some destruction of the underlying bone. These features were suggestive of osteomyelitis. Surgical excision was performed, and the mass was found to be a primary diffuse large B-cell lymphoma. The patient was administered postoperative chemotherapy, and she was in complete remission at the 1-year follow-up.
authors.affiliation: Department of Family Medicine, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA. senthilvelegambaram@yahoo.com
authors.forename: Egambaram
authors.initials: E
authors.lastname: Senthilvel
authors.forename: Shanmugam
authors.initials: S
authors.lastname: Subbiah
authors.forename: Vikas
authors.initials: V
authors.lastname: Jain
authors.forename: Michael
authors.initials: M
authors.lastname: Seidman
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis*; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery