title: Complete genome sequences for the anaerobic, extremely thermophilic plant biomass-degrading bacteria Caldicellulosiruptor hydrothermalis, Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis, Caldicellulosiruptor owensensis, and Caldicellulosiruptor lactoaceticus.
abstract: The genus Caldicellulosiruptor contains the most thermophilic, plant biomass-degrading bacteria isolated to date. Previously, genome sequences from three cellulolytic members of this genus were reported (C. saccharolyticus, C. bescii, and C. obsidiansis). To further explore the physiological and biochemical basis for polysaccharide degradation within this genus, five additional genomes were sequenced: C. hydrothermalis, C. kristjanssonii, C. kronotskyensis, C. lactoaceticus, and C. owensensis. Taken together, the seven completed and one draft-phase Caldicellulosiruptor genomes suggest that, while central metabolism is highly conserved, significant differences in glycoside hydrolase inventories and numbers of carbohydrate transporters exist, a finding which likely relates to variability observed in plant biomass degradation capacity.
authors.affiliation: Department of Chemical and Biomolecular Engineering, North Carolina State University, EB-1, 911 Partners Way, Raleigh, NC 27695-7905, USA.
authors.forename: Sara E
authors.initials: SE
authors.lastname: Blumer-Schuette
authors.forename: Inci
authors.initials: I
authors.lastname: Ozdemir
authors.forename: Dhaval
authors.initials: D
authors.lastname: Mistry
authors.forename: Susan
authors.initials: S
authors.lastname: Lucas
authors.forename: Alla
authors.initials: A
authors.lastname: Lapidus
authors.forename: Jan-Fang
authors.initials: JF
authors.lastname: Cheng
authors.forename: Lynne A
authors.initials: LA
authors.lastname: Goodwin
authors.forename: Samuel
authors.initials: S
authors.lastname: Pitluck
authors.forename: Miriam L
authors.initials: ML
authors.lastname: Land
authors.forename: Loren J
authors.initials: LJ
authors.lastname: Hauser
authors.forename: Tanja
authors.initials: T
authors.lastname: Woyke
authors.forename: Natalia
authors.initials: N
authors.lastname: Mikhailova
authors.forename: Amrita
authors.initials: A
authors.lastname: Pati
authors.forename: Nikos C
authors.initials: NC
authors.lastname: Kyrpides
authors.forename: Natalia
authors.initials: N
authors.lastname: Ivanova
authors.forename: John C
authors.initials: JC
authors.lastname: Detter
authors.forename: Karen
authors.initials: K
authors.lastname: Walston-Davenport
authors.forename: Shunsheng
authors.initials: S
authors.lastname: Han
authors.forename: Michael W W
authors.initials: MW
authors.lastname: Adams
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kelly
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D014644:Genetic Variation; D016680:Genome, Bacterial; D006026:Glycoside Hydrolases / Q000235:genetics; D006094:Gram-Positive Bacteria / Q000235:genetics*; D026901:Membrane Transport Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D026901:Membrane Transport Proteins; D006026:Glycoside Hydrolases