title: [Dietary therapy for prevention and treatment of atherosclerosis from the perspective of anti-inflammation].
abstract: Recently, many data link inflammation and atherosclerotic events and systemic inflammation are increasingly recognized as an important mediator of coronary artery disease (CAD). Indeed, experimental and epidemiological studies indicate that eating patterns, such as the traditional Mediterranean diets reduce inflammation and cardiovascular risk. These anti-inflammatory diets should be considered for the primary and secondary prevention of CAD. We must also recognize that even a transient increase in free radicals derived from inadequate food intake acutely triggers atherogenic changes including inflammation, endothelial dysfunction, hypercoagulability. Here in this review, the evidence supporting a causal link between dietary factors related to inflammatory modulators and CAD are summarized and dietary strategies for improving obesity, dyslipidemia, insulin resistance, and cardiovascular health are discussed.
authors.affiliation: Division of Metabolism and Nutrition, Department of Internal Medicine, The Jikei University Graduate School of Medicine.
authors.forename: Norio
authors.initials: N
authors.lastname: Tada
mesh_terms: D050197:Atherosclerosis / Q000178:diet therapy* / Q000209:etiology / Q000517:prevention & control*; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein; D003324:Coronary Artery Disease / Q000209:etiology / Q000517:prevention & control; D050171:Dyslipidemias; D005609:Free Radicals; D006801:Humans; D007249:Inflammation / Q000178:diet therapy* / Q000209:etiology / Q000517:prevention & control*; D007333:Insulin Resistance; D009765:Obesity; D011322:Primary Prevention; D012306:Risk; D055502:Secondary Prevention; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D015415:Biomarkers; D005609:Free Radicals; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein