title: In vivo imaging of the human rod photoreceptor mosaic.
abstract: Although single cone receptors have been imagedin vivo, to our knowledge there has been no observation of rods in the living normal eye. Using an adaptive optics ophthalmoscope and post processing, evidence of a rod mosaic was observed at 5° and 10° eccentricities in the horizontal temporal retina. For four normal human subjects, small structures were observed between the larger cones and were observed repeatedly at the same locations on different days, and with varying wavelengths. Image analysis gave spacings that agree well with rod measurements from histological data.
authors.affiliation: Center for Visual Science, University of Rochester, Rochester, New York 14627, USA. doblen@neco.edu
authors.forename: Nathan
authors.initials: N
authors.lastname: Doble
authors.forename: Stacey S
authors.initials: SS
authors.lastname: Choi
authors.forename: Johanan L
authors.initials: JL
authors.lastname: Codona
authors.forename: Julian
authors.initials: J
authors.lastname: Christou
authors.forename: Jay M
authors.initials: JM
authors.lastname: Enoch
authors.forename: David R
authors.initials: DR
authors.lastname: Williams
mesh_terms: D000328:Adult; D006801:Humans; D007091:Image Processing, Computer-Assisted; D057054:Molecular Imaging / Q000379:methods*; D017948:Retinal Rod Photoreceptor Cells / Q000166:cytology*; D055815:Young Adult