title: The role of the nucleus accumbens in knowing when to respond.
abstract: While knowing what to expect is important, it is equally important to know when to expect it and to respond accordingly. This is apparent even in simple Pavlovian training situations in which animals learn to respond more strongly closer to reward delivery. Here we report that the nucleus accumbens core, an area well-positioned to represent information about the timing of impending rewards, plays a critical role in this timing function.
authors.affiliation: Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
authors.forename: Teghpal
authors.initials: T
authors.lastname: Singh
authors.forename: Michael A
authors.initials: MA
authors.lastname: McDannald
authors.forename: Yuji K
authors.initials: YK
authors.lastname: Takahashi
authors.forename: Richard Z
authors.initials: RZ
authors.lastname: Haney
authors.forename: Nisha K
authors.initials: NK
authors.lastname: Cooch
authors.forename: Federica
authors.initials: F
authors.lastname: Lucantonio
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Schoenbaum
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D003463:Cues; D009714:Nucleus Accumbens / Q000293:injuries / Q000502:physiology*; D051381:Rats; D011930:Reaction Time / Q000502:physiology*; D012201:Reward