title: Complications after aortic arch hybrid repair.
abstract: OBJECTIVE
  To analyze early and midterm complications after hybrid aortic arch repair (HAR).
  
  
  METHODS
  Between January 1997 and November 2009 among 259 patients receiving thoracic endovascular aortic repair, HAR has been performed in 47 patients (median age, 64.5 years; range, 41-84). A retrospective analysis was performed. Complete supra-aortic debranching was performed in 15 patients (32%) and partial debranching in 23 patients (49%). Isolated left subclavian artery revascularization prior to thoracic endovascular aortic repair has been used in nine patients (19%). Emergency procedures were performed in 34% of all patients.
  
  
  RESULTS
  The overall in-hospital mortality was 19% (9/47 patients), 27% after complete and 15.6% after partial debranching. Postoperative complications occurred in 32 patients (68%). Cardiocirculatory complications were observed in seven patients (15%). Pulmonary complications occurred in 12 patients (26%). A total of five patients (11%) experienced renal complications requiring hemodialysis. The stroke rate was 6.3%. Paraplegia was seen in three patients (6%). Proximal type I endoleaks were observed in seven patients. Retrograde aortic arch dissection was seen in three patients (6.3%). Cox proportional hazard regression showed the necessity for an emergency procedure as an independent predictor of death (hazard ratio, 2.9; 95% confidence interval, 1.1-7.5; P = .023). The reintervention rate was 27.6% with three patients requiring open conversion.
  
  
  CONCLUSIONS
  Hybrid aortic arch repair in high-risk patients is associated with a relevant morbidity, mortality, and reintervention rate. Patient selection is crucial and indication should be limited to patients not suitable for conventional aortic arch repair or emergency cases at present. Therefore, we recommend performing HAR only in high-volume centers with cardiovascular surgical cooperation.
authors.affiliation: Department of Vascular and Endovascular Surgery, Ruprecht-Karls University Heidelberg, Heidelberg, Germany. Philipp.Geisbuesch@med.uni-heidelberg.de
authors.forename: Philipp
authors.initials: P
authors.lastname: Geisbüsch
authors.forename: Drosos
authors.initials: D
authors.lastname: Kotelis
authors.forename: Matthias
authors.initials: M
authors.lastname: Müller-Eschner
authors.forename: Alexander
authors.initials: A
authors.lastname: Hyhlik-Dürr
authors.forename: Dittmar
authors.initials: D
authors.lastname: Böckler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D001018:Aortic Diseases / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation / Q000401:mortality; D017558:Elective Surgical Procedures; D057867:Endoleak / Q000209:etiology; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000295:instrumentation / Q000401:mortality; D005260:Female; D005858:Germany; D006083:Graft Occlusion, Vascular / Q000209:etiology; D017052:Hospital Mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D007674:Kidney Diseases / Q000209:etiology / Q000628:therapy; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology; D018579:Patient Selection; D016016:Proportional Hazards Models; D006435:Renal Dialysis; D012086:Reoperation; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D020521:Stroke / Q000209:etiology; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex