title: Statin-induced focal myositis of the upper extremity. A report of two cases.
abstract: Statins are widely used to lower increased cholesterol levels with the aim to prevent major cardiovascular events. However, they bare the risk of myotoxic side effects. We report on two patients with focal weakness and pain in the upper extremities. In both patients, abnormal MRI signal heights in the muscle groups involved were indicative of the final diagnosis of focal myositis during statin therapy.
authors.affiliation: Department of Radiology, Herz- und Gefäßklinik GmbH, Salzburger Leite 1, D-97616 Bad Neustadt an der Saale, Germany. wagner.radiologie@herzchirurgie.de
authors.forename: M
authors.initials: M
authors.lastname: Wagner
authors.forename: M
authors.initials: M
authors.lastname: Mühldorfer-Fodor
authors.forename: K J
authors.initials: KJ
authors.lastname: Prommersberger
authors.forename: R
authors.initials: R
authors.lastname: Schmitt
mesh_terms: D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D000960:Hypolipidemic Agents / Q000009:adverse effects; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000187:drug effects / Q000473:pathology*; D009220:Myositis / Q000139:chemically induced* / Q000473:pathology*; D034941:Upper Extremity / Q000473:pathology*
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents