title: Efficacy of eprinomectin pour-on treatment in sheep naturally infected with Dictyocaulus filaria and Cystocaulus ocreatus.
abstract: The efficacy of eprinomectin on Dictyocaulus filaria and Cystocaulus ocreatus in naturally infected sheep was evaluated in the present study. In total, 30 infected sheep were randomly divided into two groups: treated (n = 15) and untreated (n = 15). A single pour-on dose of eprinomectin (0.5 mg/kg) was administered to the treated group. No medication was used in the untreated group. Faecal larval counts were performed on pre-treatment (day 0) and post-treatment (days 7, 14, 21 and 42) days. Eprinomectin was found to be 100% effective against D. filaria on day 7 post-treatment when compared with the untreated group and it maintained this effect on days 14, 21 and 42. However, the decrease in faecal larval count of C. ocreatus was found to be 86, 86 and 91%, on days 14, 21 and 42, respectively.
authors.affiliation: Department of Parasitology, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey. feridekircali@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Kırcalı Sevimli
authors.forename: E
authors.initials: E
authors.lastname: Kozan
authors.forename: N
authors.initials: N
authors.lastname: Doğan
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D004021:Dictyocaulus / Q000145:classification / Q000187:drug effects*; D004022:Dictyocaulus Infections / Q000188:drug therapy* / Q000469:parasitology; D005243:Feces / Q000469:parasitology; D005260:Female; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012107:Research Design; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000469:parasitology; D017183:Strongylida / Q000145:classification / Q000187:drug effects*; D017206:Strongylida Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D007559:Ivermectin; C101434:eprinomectin