title: Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk 'Golden Years' type 1 diabetes cohort.
abstract: The C-allele of rs266729 is associated with CHD, while the G-allele of rs17300539 is associated with metabolic traits. We examined these in type 1 diabetes. For rs266729, the C-allele was associated with 8-fold increase in CHD. For rs17300539, the G-allele was associated with increases in triglycerides and waist circumference.
authors.affiliation: Diabetes Research Group, Institute of Life Science, Swansea University, Swansea SA2 8PP, UK. s.l.prior@swansea.ac.uk
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Prior
authors.forename: Danielle A
authors.initials: DA
authors.lastname: Jones
authors.forename: Geoffrey V
authors.initials: GV
authors.lastname: Gill
authors.forename: Steve C
authors.initials: SC
authors.lastname: Bain
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Stephens
mesh_terms: D052242:Adiponectin / Q000235:genetics; D000368:Aged; D003327:Coronary Disease / Q000150:complications / Q000235:genetics*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D017354:Point Mutation; D020641:Polymorphism, Single Nucleotide; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference / Q000235:genetics
chemical_list: C499918:ADIPOQ protein, human; D052242:Adiponectin; D014280:Triglycerides