title: [Neuroimaging in brain tumors].
abstract: Advances in neuroimaging have modified diagnosis, treatment and clinical management of brain tumors. However, neuropathological study remains necessary in order to get the best clinical management. Surgery and radiotherapy planning are imaging-dependent procedures, and MRI is the standard imaging modality for determining precisely tumor location and its anatomical relationship with surrounding brain structures. In high-grade tumors it has been accepted that tumoral areas with contrast uptake in CT, or T1-weighted MRI contrast enhancement corresponds to solid tumor. However, relationship between MRI and invasive tumor areas remains less defined. Therefore, it is generally accepted that conventional MRI is not sufficient to delineate the real extension of brain tumors. In recent years, PET using 18FDG and amino acid radiotracers ((11)C-Methionine, (18)FDOPA, (18)FET) and SPECT with (201-)Thallium, as well as advanced MRI sequences (Perfusion, Diffusion-weighted, Diffusion tensor imaging and tractography), and functional MRI, have added important complementary information in the characterization, therapy planning and recurrence differential diagnosis of brain tumors. In this continuing education review of neuroimaging in brain tumors, technical aspects and clinical applications of different imaging modalities are approached in a multidisciplinary way.
authors.affiliation: Servicio de Medicina Nuclear, Clínica Universidad de Navarra, Pamplona, Navarra, España. jarbizu@unav.es
authors.forename: J
authors.initials: J
authors.lastname: Arbizu
authors.forename: P D
authors.initials: PD
authors.lastname: Domínguez
authors.forename: R
authors.initials: R
authors.lastname: Diez-Valle
authors.forename: C
authors.initials: C
authors.lastname: Vigil
authors.forename: R
authors.initials: R
authors.lastname: García-Eulate
authors.forename: J L
authors.initials: JL
authors.lastname: Zubieta
authors.forename: J A
authors.initials: JA
authors.lastname: Richter
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging / Q000379:methods*; D003943:Diagnostic Techniques, Neurological; D056324:Diffusion Tensor Imaging / Q000379:methods; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D055420:Perfusion Imaging / Q000379:methods; D049268:Positron-Emission Tomography / Q000379:methods; D015641:Radiography, Interventional / Q000379:methods; D019275:Radiopharmaceuticals; D025321:Surgery, Computer-Assisted; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals