title: [Study of incidence and correlation factors of depression, anxiety and insomnia in patients with myasthenia gravis].
abstract: OBJECTIVE
  To investigate the incidence rate and correlation factors of depression, anxiety and insomnia in patients with myasthenia gravis (MG).
  
  
  METHODS
  A total of 161 MG patients were assessed and graded with HAMD, HAMA, PSQI, QMG, ADL and a self-made scale chart. And the correlation factors were analyzed by Logistic stepwise regression.
  
  
  RESULTS
  The prevalence of depression, anxiety and insomnia was 58.3%, 45.3% and 39.1% respectively. The correlation factors with significant influences on MG were as follows: depression with age, physical weakness, score of QMG, life scale grading; anxiety with experience-sharing; insomnia age, dyspnea, thymoma, physical status at 1 month post-operation, prednisone dose and score of QMG.
  
  
  CONCLUSIONS
  Nearly one half of the MG patients suffer from affective disorders to different degrees. And an analysis of its correlation factors provides references to prevent and treat the affective disorders concurrently with MG.
authors.affiliation: Department of Neurology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Li
authors.initials: L
authors.lastname: Qiu
authors.forename: Hui-yu
authors.initials: HY
authors.lastname: Feng
authors.forename: Xin
authors.initials: X
authors.lastname: Huang
authors.forename: Rong
authors.initials: R
authors.lastname: Mo
authors.forename: Chang-yi
authors.initials: CY
authors.lastname: Ou
authors.forename: Chuan-ming
authors.initials: CM
authors.lastname: Luo
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Wei-bin
authors.initials: WB
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology*; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000453:epidemiology* / Q000523:psychology; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology*; D055815:Young Adult