title: A comparative pilot study of low intensity laser versus topical corticosteroids in the treatment of erosive-atrophic oral lichen planus.
abstract: OBJECTIVE
  Treatment of oral lichen planus (OLP) remains a great challenge for clinicians. The aim of our study was to compare the effect of low intensity laser therapy (LILT) with topical corticosteroids in the treatment of oral erosive and atrophic lichen planus.
  
  
  METHODS
  Thirty patients with erosive-atrophic OLP were randomly allocated into two groups. The experimental group consisted of patients treated with the 630  nm diode laser. The control group consisted of patients who used Dexamethason mouth wash. Response rate was defined based on changes in the appearance score and pain score (Visual Analogue Scale) of the lesions before and after each treatment.
  
  
  RESULTS
  Appearance score, pain score, and lesion severity was reduced in both groups. No significant differences were found between the treatment groups regarding the response rate and relapse.
  
  
  CONCLUSIONS
  Our study demonstrated that LILT was as effective as topical corticosteroid therapy without any adverse effects and it may be considered as an alternative treatment for erosive-atrophic OLP in the future.
authors.affiliation: Department of Oral Medicine and Dental Research Center, Faculty of Dentistry, Mashhad, Iran.
authors.forename: Hasan Hoseinpour
authors.initials: HH
authors.lastname: Jajarm
authors.forename: Farnaz
authors.initials: F
authors.lastname: Falaki
authors.forename: Omid
authors.initials: O
authors.lastname: Mahdavi
mesh_terms: D000328:Adult; D001284:Atrophy; D003907:Dexamethasone / Q000008:administration & dosage*; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D017676:Lichen Planus, Oral / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D028022:Low-Level Light Therapy; D009067:Mouthwashes; D010147:Pain Measurement
chemical_list: D005938:Glucocorticoids; D009067:Mouthwashes; D003907:Dexamethasone