title: Actin motility: formin a SCAry tail.
abstract: A new biochemical analysis has revealed that the Rickettsia bacterial protein Sca2--recently shown to be essential for virulence and actin-dependent motility--assembles actin filaments using a mechanism that functionally resembles the processive elongation tactics used by formins.
authors.affiliation: Laboratory of Cell Structure & Signal Integration, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Art.Alberts@vai.org
authors.forename: Art
authors.initials: A
authors.lastname: Alberts
authors.forename: Michael
authors.initials: M
authors.lastname: Way
mesh_terms: D000199:Actins / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D003599:Cytoskeleton; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology; D012281:Rickettsia / Q000378:metabolism* / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D000199:Actins; D001426:Bacterial Proteins