title: Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans.
abstract: An efficient palladium/copper-catalyzed approach to the synthesis of highly substituted 3-formyl furans from the reactions of readily available α-bromoenaminones with terminal alkynes has been developed. This methodology was realized by the cascade reactions of Sonogashira coupling and the subsequent intramolecular cyclization.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Institute of Medicinal Chemistry, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, People's Republic of China.
authors.forename: Jingyu
authors.initials: J
authors.lastname: Yang
authors.forename: Chengyu
authors.initials: C
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Xie
authors.forename: Hongfeng
authors.initials: H
authors.lastname: Li
authors.forename: Ende
authors.initials: E
authors.lastname: Li
authors.forename: Yanzhong
authors.initials: Y
authors.lastname: Li