title: Lymphoepithelioma-like carcinoma of the vulva, an underrecognized entity? Case report with a single inguinal micrometastasis detected by sentinel node technique.
abstract: This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy. Follow-up nine months later showed only slight vulvar atrophy, without signs of local recurrence or distant metastases.Although lymphoepithelioma-like carcinomas of the skin and the female genital tract are presumed to have a better prognosis than their counterparts in the upper aerodigestive tract, possibly due to earlier detection and therapy, this case documents their potential for early metastasis.
authors.affiliation: Department of Pathology, Krankenhaus Barmherzige Schwestern, Linz, Austria. hans-christian.boesmueller@bhs.at
authors.forename: Hans
authors.initials: H
authors.lastname: Bösmüller
authors.forename: Sophie
authors.initials: S
authors.lastname: Haitchi-Petnehazy
authors.forename: Christine
authors.initials: C
authors.lastname: Gruber
authors.forename: Franz
authors.initials: F
authors.lastname: Roithmeier
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Stummvoll
authors.forename: Gerald
authors.initials: G
authors.lastname: Webersinke
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000532:radiotherapy; D011878:Radiotherapy; D021701:Sentinel Lymph Node Biopsy; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000175:diagnosis* / Q000601:surgery