title: Comparison of carotid and cerebrovascular disease between diabetic and non-diabetic patients using dual-source CT.
abstract: OBJECTIVE
  To clarify the differences of the carotid and cerebrovascular disease between patients with and without type 2 diabetes using dual-source CT angiography.
  
  
  METHODS
  Dual-source CT angiography of the carotid and cerebrovascular arteries was performed in 79 type 2 diabetic patients and 207 non-diabetic patients. The type, extent and distribution of plaques, and luminal stenosis were compared.
  
  
  RESULTS
  Compared with non-diabetic patients, diabetic patients had a higher overall incidence of plaque (p<0.05) and cerebral infarction (p<0.05). Among these plaques, no differences were observed in the subtype of plaques between these two cohorts (all p>0.05), as well as for the number of diseased segments and the distribution of plaques; both mainly involved the bilateral cavernous segment of the internal carotid artery. As for the stenosis, non-obstructive lesions were more common in diabetic patients (p<0.05). There was no difference in the segment number of stenosis (≥30% and ≥70%) between these two groups (all p>0.05).
  
  
  CONCLUSIONS
  Diabetes is associated with a higher incidence of plaque and non-obstructive stenosis. However, no significant differences were observed in the type, extent and distribution of involved plaques between diabetic and non-diabetic patients.
authors.affiliation: Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
authors.forename: Ci
authors.initials: C
authors.lastname: He
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Yang
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Chu
authors.forename: Zhi-hui
authors.initials: ZH
authors.lastname: Dong
authors.forename: Yun-ming
authors.initials: YM
authors.lastname: Li
authors.forename: Heng
authors.initials: H
authors.lastname: Shao
authors.forename: Wen
authors.initials: W
authors.lastname: Deng
mesh_terms: D000368:Aged; D002340:Carotid Artery Diseases / Q000150:complications* / Q000000981:diagnostic imaging*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000000981:diagnostic imaging*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging*; D058065:Diabetic Cardiomyopathies / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*