title: [Effect of pharmacist involvement in adherence to medications in patients with high to moderate cardiovascular risk (Study EMDADER-CV-INCUMPLIMIENTO)].
abstract: OBJECTIVE
  To evaluate the effect of pharmacist involvement, by means of Pharmacotherapy Follow-Up (PFU) in the improvement of medication adherence and therapeutic outcomes.
  
  
  METHODS
  An experimental, controlled, and randomised clinical study comparing a PFU program with the routine process in Spanish community pharmacies improved with health education during 8 months.
  
  
  METHODS
  Nine Spanish community pharmacies.
  
  
  METHODS
  Patients between 25 and 74 years with a moderate-high cardiovascular risk (CVR), who arrived with a prescription, in their name, for drugs for at least one CVR factor.
  
  
  METHODS
  The patients were randomly assigned to the intervention group (IG), and received PFU and health education, or the control group (CG), who received health education only.
  
  
  METHODS
  Adherence to treatment, and blood pressure (BP) and total cholesterol (TC) levels at the beginning and end of the study.
  
  
  RESULTS
  Of the 87 patients enrolled, 85 finished the study: 41 from the CG and 44 from the IG. Both groups increased adherence at the end of the [CG: 26.9%; 95% CI: 12.7- 41; IG: 27.3%; 95% CI: 13.6 - 41]. Although the IG showed better results in the variation of BP and TC levels, the differences compared to the CG were not statistically significant.
  
  
  CONCLUSIONS
  PFU and health education improves adherence to treatment. To be a patient who completes the study is also associated with improvement in the blood pressure and blood pressure/total cholesterol objectives.
authors.affiliation: Doctor en Farmacia, Experto Universitario en Seguimiento Farmacoterapéutico por la Universidad de Granada, Farmacéutico Comunitario en Talavera de la Reina, Toledo, España. miguelrodriguez@redfarma.org
authors.forename: Miguel Ángel Rodríguez
authors.initials: MÁ
authors.lastname: Chamorro
authors.forename: Emilio
authors.initials: E
authors.lastname: García-Jiménez
authors.forename: Pedro
authors.initials: P
authors.lastname: Amariles
authors.forename: Alfonso Rodríguez
authors.initials: AR
authors.lastname: Chamorro
authors.forename: Eva María Pérez
authors.initials: EM
authors.lastname: Merino
authors.forename: Fernando Martínez
authors.initials: FM
authors.lastname: Martínez
authors.forename: María José Faus
authors.initials: MJ
authors.lastname: Dader
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D010595:Pharmacists; D024382:Professional Role; D012307:Risk Factors; D016903:Drug Monitoring