title: Development of silica-based stationary phases for high-performance liquid chromatography.
abstract: Stationary phases are the basis of the development and application of high-performance liquid chromatography (HPLC). In this review we focused on the development of silica-based stationary phases, including the synthesis of silica gel and the application of silica in hydrophilic interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), chiral separation chromatography, and ion chromatography. New stationary phases, advances in ionic liquid-modified silica, silica-based core-shell materials, and silica-based monolithic columns for HPLC are introduced separately.
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
authors.forename: Hongdeng
authors.initials: H
authors.lastname: Qiu
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Liang
authors.forename: Min
authors.initials: M
authors.lastname: Sun
authors.forename: Shengxiang
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D012822:Silicon Dioxide / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D012822:Silicon Dioxide