title: Surgical outcome of hepatocellular carcinoma patients with biliary tumor thrombi.
abstract: BACKGROUND
  To investigate the surgical outcome of hepatocellular carcinoma (HCC) patients with biliary tumor thrombi (BTT).
  
  
  METHODS
  Surgical outcome of 27 HCC patients with BTT (group I) were compared with randomly selected HCC patients without BTT (group II; n = 270).
  
  
  RESULTS
  One patient in group I died of hepatic failure within 30 days after resection. The 1-, 3- and 5-year cumulative survival rates of group I were 70.3%, 25.9%, and 7.4%, respectively; these were significantly lower than those of group II (90.6%, 54.0%, and 37.7%) (P <0.001). The rates of early recurrence (≤ 1 year) after resection were significantly higher in group I than group II (70.3% vs. 34.8%) (P < 0.001).
  
  
  CONCLUSIONS
  HCC patients with BTT had a worse prognosis after resection than those without BTT. Resection should be considered for these tumors given the lack of effective alternative therapies.
authors.affiliation: Department of Hepato-Biliary-Pancreato-Vascular Surgery, First Affiliated Hospital of Xiamen University, Xiamen, PR China.
authors.forename: Wenyu
authors.initials: W
authors.lastname: Shao
authors.forename: Chengjun
authors.initials: C
authors.lastname: Sui
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Liu
authors.forename: Jiamei
authors.initials: J
authors.lastname: Yang
authors.forename: Yanming
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D002779:Cholestasis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D013927:Thrombosis / Q000209:etiology*; D016896:Treatment Outcome; D047368:Tumor Burden