title: Nasopharyngeal inflammatory pseudotumor showing abducens nerve palsy.
abstract: Inflammatory pseudotumor (IPT) originated from the nasopharynx is very rare. To the authors' best knowledge, nasopharyngeal pseudotumor accompanied by abducens nerve palsy due to cavernous sinus invasion has not been reported previously. A 28-year-old male presented with abrupt-onset diplopia and right side severe headache. Physical examination revealed a mild contour bulging mass without mucosal ulceration or necrosis in the nasopharynx. The mass was thought to be a malignant neoplasm such as a carcinoma due to ill-defined, infiltrative tumor extended to the right parapharyngeal, carotid, prevertebral spaces and cavernous sinus on MR images, and hypermetabolic lesion on PET/CT. Histopathology demonstrated inflammatory pseudotumor. The patient was treated with high-dose of oral steroid, and then headache and diplopia was dramatically improved. Although IPT of the nasopharynx is very rare, it is important for otolaryngologists to be aware of this disease process.
authors.affiliation: Department of Otorhinolaryngology and Medical Research Institute, Pusan National University School of Medicine, Busan, South Korea.
authors.forename: Kyu-Sup
authors.initials: KS
authors.lastname: Cho
authors.forename: Hak-Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Chang-Hun
authors.initials: CH
authors.lastname: Lee
authors.forename: Hwan-Jung
authors.initials: HJ
authors.lastname: Roh
mesh_terms: D020434:Abducens Nerve Diseases / Q000209:etiology*; D000284:Administration, Oral; D000328:Adult; D002426:Cavernous Sinus / Q000473:pathology*; D004305:Dose-Response Relationship, Drug; D005938:Glucocorticoids / Q000008:administration & dosage; D006104:Granuloma, Plasma Cell / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009302:Nasopharyngeal Diseases / Q000150:complications* / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D011239:Prednisolone / Q000008:administration & dosage; D035583:Rare Diseases; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone