title: An enucleated duodenal gastrinoma with multiple type 1 endocrine neoplasia located by selective arterial calcium injection.
abstract: We report a duodenal gastrinoma in a 50-year-old man who was admitted to our hospital with tarry stools. Esophagogastroduodenoscopy revealed multiple ulcers in the duodenal bulb and a submucosal tumor in the descending duodenum. His serum gastrin level was 1400pg/ml. We suspected Zollinger-Ellison syndrome and performed selective arterial calcium injection to locate the gastrinoma. Increase in the hepatic venous gastrin level was seen only in the gastroduodenal artery area. We diagnosed a gastrinoma located in the pancreaticoduodenal area. Genetic examination showed a single-base deletion in the MEN-1 gene. At operation, the tumor was found in the submucosal layer of the descending duodenum and was extirpated. He is alive without recurrence 3 years after surgery.
authors.affiliation: Department of Gastroenterology, Yamagata City Hospital Saiseikan. hshouji@ncc.go.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Shoji
authors.forename: Michio
authors.initials: M
authors.lastname: Kuroki
authors.forename: Eriko
authors.initials: E
authors.lastname: Nakano
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Hiramoto
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Matsumura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miura
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Hirakawa
authors.forename: Mikio
authors.initials: M
authors.lastname: Matsuda
mesh_terms: D002125:Calcium Gluconate / Q000008:administration & dosage; D004379:Duodenal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D015408:Gastrinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications*; D011859:Radiography
chemical_list: D002125:Calcium Gluconate