title: Synthesis and characterization of 5-hydroxymethyl-5-methyl-pyrroline N-oxide and its derivatives.
abstract: Synthesis and spin trapping behavior of three novel DMPO derivatives, namely 5-hydroxymethyl-5-methyl-pyrroline N-oxide (HMMPO), 5-(2-furanyl)-oxymethyl-5-methyl-pyrroline N-oxide (FMMPO), and 5-(2-pyranyl)-oxymethyl-5-methyl-pyrroline N-oxide (PMMPO) towards different oxygen- and carbon-centered radicals are described. The stabilizing effect of a series of cyclodextrins on the superoxide adducts was tested.
authors.affiliation: Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Austria. klaus.stolze@vetmeduni.ac.at
authors.forename: Klaus
authors.initials: K
authors.lastname: Stolze
authors.forename: Natascha
authors.initials: N
authors.lastname: Rohr-Udilova
authors.forename: Anjan
authors.initials: A
authors.lastname: Patel
authors.forename: Thomas
authors.initials: T
authors.lastname: Rosenau
mesh_terms: D003497:Cyclic N-Oxides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D017665:Hydroxyl Radical / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C557926:5-(2-furanyl)oxymethyl-5-methyl-pyrroline N-oxide; C557925:5-(2-pyranyl)oxymethyl-5-methylpyrroline N-oxide; C557927:5-hydroxymethyl-5-methyl-pyrroline N-oxide; D003497:Cyclic N-Oxides; D011758:Pyrroles; C051224:methyl radical; C013231:pyrroline; D017665:Hydroxyl Radical; D008697:Methane