title: [Herpes zoster: clinical manifestation, diagnosis and treatment].
abstract: Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show that early recognition and treatment can reduce acute symptoms, that antiviral therapy and corticosteroids shorten the acute illness period, that opioids and anticonvulsants have effect on acute HZ pain and, finally, that tricyclic antidepressants, opioids and anticonvulsants all have proven efficiency in PHN therapy.
authors.affiliation: Dermato-venerologisk Afdeling D41, Bispebjerg Hospital, 2400 København NV, Denmark. kkof0013@bbh.regionh.dk
authors.forename: Kristian
authors.initials: K
authors.lastname: Kofoed
authors.forename: Finn
authors.initials: F
authors.lastname: Rønholt
authors.forename: Jan
authors.initials: J
authors.lastname: Gerstoft
authors.forename: Carsten
authors.initials: C
authors.lastname: Sand
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage / Q000009:adverse effects; D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects; D002648:Child; D004359:Drug Therapy, Combination; D006562:Herpes Zoster / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D051474:Neuralgia, Postherpetic / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000700:Analgesics; D000701:Analgesics, Opioid; D000927:Anticonvulsants; D000929:Antidepressive Agents, Tricyclic; D000998:Antiviral Agents