title: Pure apocrine nevus: immunohistochemical study of a new case and literature review.
abstract: Apocrine nevi are benign adnexal cutaneous hamartomas characterized by localized hyperplasia of mature apocrine sweat glands (ASG). Although ASG proliferation can be found in a number of acquired or congenital adnexal skin tumors, pure apocrine nevi are exceedingly rare. We present herein a new typical case of this tumor that was studied immunohistochemically, and review the relevant literature in order to delineate its clinicopathological features.
authors.affiliation: Department of Dermatology and Laboratory of Dermatopathology, Edouard Herriot Hospital, Lyon, France. jean.kanitakis@univ-lyon1.fr
authors.forename: J
authors.initials: J
authors.lastname: Kanitakis
authors.forename: K
authors.initials: K
authors.lastname: Kyamidis
authors.forename: A
authors.initials: A
authors.lastname: Toussinas
authors.forename: G
authors.initials: G
authors.lastname: Tsoïtis
mesh_terms: D000328:Adult; D001050:Apocrine Glands / Q000473:pathology* / Q000601:surgery; D002352:Carrier Proteins / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006222:Hamartoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D053552:Keratin-7 / Q000378:metabolism; D019394:Ki-67 Antigen / Q000378:metabolism; D008297:Male; D008565:Membrane Proteins / Q000378:metabolism; D026901:Membrane Transport Proteins; D009506:Nevus / Q000473:pathology* / Q000601:surgery; D013544:Sweat Gland Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: C081876:CKAP4 protein, human; D002352:Carrier Proteins; D006023:Glycoproteins; C507497:KRT7 protein, human; D053552:Keratin-7; D019394:Ki-67 Antigen; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; C488892:PIP protein, human