title: High-dose methotrexate-induced renal dysfunction: is glucarpidase necessary for rescue?
authors.forename: Paul A
authors.initials: PA
authors.lastname: Meyers
authors.forename: Carlos
authors.initials: C
authors.lastname: Flombaum
mesh_terms: D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D011322:Primary Prevention / Q000379:methods; D051437:Renal Insufficiency / Q000139:chemically induced / Q000517:prevention & control*; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome; D011623:gamma-Glutamyl Hydrolase / Q000008:administration & dosage*
chemical_list: D011623:gamma-Glutamyl Hydrolase; D008727:Methotrexate