title: Predictors of anxiety and depression among people attending diabetes screening: a prospective cohort study embedded in the ADDITION (Cambridge) randomized control trial.
abstract: OBJECTIVE
  This study aimed to identify factors predicting anxiety and depression among people who attend primary care-based diabetes screening.
  
  
  METHODS
  A prospective cohort study embedded in the ADDITION (Cambridge) randomized control trial.
  
  
  METHODS
  Participants (N= 3,240) at risk of diabetes were identified from 10 primary care practices and invited to a stepwise screening programme as part of the ADDITION (Cambridge) trial. Main outcome measures were anxiety and depression at 12 months post-screening assessed using the Hospital Anxiety and Depression Scale (HADS).
  
  
  RESULTS
  Hierarchical linear regressions showed that demographic, clinical, and psychological variables collectively accounted for 52% of the variance in HADS anxiety scores and 53% of the variance in HADS depression scores 12 months after diabetes screening. Screening outcome (positive or negative for diabetes) was not related to differences in anxiety or depression at 12 months. Higher number of self-reported (diabetes) symptoms after first attendance was associated with higher anxiety and depression at 12-month follow-up, after controlling for anxiety and depression after first attendance.
  
  
  CONCLUSIONS
  Participants in a diabetes screening programme showed low scores on anxiety and depression scales after first appointment and 1 year later. Diagnosis of diabetes was shown to have a limited psychological impact and may be less important than symptom perception in determining emotional outcomes after participation in diabetes screening.
authors.affiliation: General Practice and Primary Care Research Unit, University of Cambridge, UK. camp3@medschl.cam.ac.uk
authors.forename: C A M
authors.initials: CA
authors.lastname: Paddison
authors.forename: H C
authors.initials: HC
authors.lastname: Eborall
authors.forename: D P
authors.initials: DP
authors.lastname: French
authors.forename: A L
authors.initials: AL
authors.lastname: Kinmonth
authors.forename: A T
authors.initials: AT
authors.lastname: Prevost
authors.forename: S J
authors.initials: SJ
authors.lastname: Griffin
authors.forename: S
authors.initials: S
authors.lastname: Sutton
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000523:psychology; D001294:Attitude to Health; D015331:Cohort Studies; D015897:Comorbidity; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000523:psychology* / Q000706:statistics & numerical data; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D006113:United Kingdom / Q000453:epidemiology