title: The path to wearable ultrafiltration and dialysis devices.
abstract: Wearable blood processing devices offer an attractive solution to problems inherent in clinic-based, intermittent end-stage renal disease therapies. What is involved in transitioning even a part of the current clinic-based population to ambulatory therapy has not been clearly enumerated. This paper addresses what a first-generation wearable device might accomplish, how issues of safety will need to be addressed, and what will make the device attractive to, and manageable by, the patient. Medical, technological, and economic issues are identified.
authors.affiliation: Artificial Organs Research Laboratory, Department of Chemical Engineering, Columbia University, 500 West 120 Street, New York, NY 10027, USA. leonard@columbia.edu
authors.forename: Edward F
authors.initials: EF
authors.lastname: Leonard
authors.forename: Stanley
authors.initials: S
authors.lastname: Cortell
authors.forename: James
authors.initials: J
authors.lastname: Jones
mesh_terms: D004867:Equipment Design; D006801:Humans; D007676:Kidney Failure, Chronic / Q000191:economics / Q000628:therapy; D006435:Renal Dialysis / Q000191:economics / Q000295:instrumentation*; D014462:Ultrafiltration / Q000191:economics / Q000295:instrumentation*