title: Nano-encapsulation as high pressure devices for folding-unfolding proteins.
abstract: This communication focuses on the capillary pressure effect in nano-objects. Indeed the change in pressure inside encapsulated biomaterials due to capillary effects can drastically alter the chemical equilibrium and the kinetics of biological reactions. This can potentially be exploited to design specific encapsulations in hollow solid nano-spheres or nano-tubes as carriers to optimise biochemical processes.
authors.affiliation: ISM2-AD2M, UMR 6263, Université Paul Cezanne, Bd Escadrille Normandie Niemen, 13397 Marseille Cedex 20, France. annie.sanfeld@univ-cezanne.fr
authors.forename: A
authors.initials: A
authors.lastname: Steinchen
authors.forename: K
authors.initials: K
authors.lastname: Sefiane
authors.forename: A
authors.initials: A
authors.lastname: Sanfeld
mesh_terms: D004337:Drug Carriers / Q000737:chemistry / Q000378:metabolism; D004339:Drug Compounding / Q000379:methods*; D007700:Kinetics; D054118:Nanospheres / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods; D043942:Nanotubes / Q000737:chemistry; D011312:Pressure; D017510:Protein Folding; D058767:Protein Unfolding; D011506:Proteins / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D004337:Drug Carriers; D011506:Proteins