title: [Two cases of lung cancer patients with postoperative brain metastases obtaining long-term survival after gamma knife radiosurgery].
abstract: We report two cases of lung cancer patients with postoperative solitary brain metastases obtaining long-term survival after gamma knife stereotactic radiosurgery. Both were seventies men and had good performance status without active extracranial disease. In one case, an asymptomatic metastatic brain tumor 1.8 cm in maximum diameter appeared one year and two months after the operation and was irradiated with gamma knife resulting in complete local control for seven years. He is alive with solitary lung metastasis in good performance status. In the other case, gamma knife was employed for a metastatic brain tumor 2.7 cm in maximum diameter that appeared nine months after the operation accompanying incomplete left hemiplegia. Six months later, the tumor was enlarged and gamma knife was repeated, but the tumor growth could not be suppressed. Following deterioration of hemiplegia and appearance of convulsion, he died of neurological disorder three years and two months after the onset of brain metastasis. Gamma knife stereotactic radiosurgery for metastatic brain tumors is less invasive and a repeatable technique, and is expected to provide a good local control and a survival benefit for appropriately selected patients.
authors.affiliation: Dept. of Surgery, Suita Municipal Hospital.
authors.forename: Hideoki
authors.initials: H
authors.lastname: Yokouchi
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Nagase
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ide
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Ryota
authors.initials: R
authors.lastname: Mukai
authors.forename: Hideo
authors.initials: H
authors.lastname: Ota
authors.forename: Kentaro
authors.initials: K
authors.lastname: Maruyama
authors.forename: Kohei
authors.initials: K
authors.lastname: Murata
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Tamai
authors.forename: Yasuyoshi
authors.initials: Y
authors.lastname: Miyao
authors.forename: Hisae
authors.initials: H
authors.lastname: Mori
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D011183:Postoperative Complications; D016634:Radiosurgery