title: Absence of quenching by [Fe(CN)6]4- is not proof of DNA intercalation.
abstract: The quenching of the (3)MLCT emission of three Ru(II) complexes of known DNA binding mode is compared. This work shows that relative binding constants dictate whether quenching is observed in the presence of DNA rather than protection of the probe by intercalation, as has been commonly stated.
authors.affiliation: Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Burya
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Lutterman
authors.forename: Claudia
authors.initials: C
authors.lastname: Turro
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry / Q000378:metabolism; D001665:Binding Sites; D002413:Cations, Divalent / Q000737:chemistry / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D005292:Ferricyanides / Q000737:chemistry* / Q000378:metabolism; D007364:Intercalating Agents / Q000737:chemistry* / Q000378:metabolism; D049449:Luminescence; D008163:Luminescent Measurements / Q000379:methods; D009942:Organometallic Compounds / Q000737:chemistry* / Q000378:metabolism; D012428:Ruthenium / Q000737:chemistry / Q000378:metabolism
chemical_list: D002413:Cations, Divalent; D005292:Ferricyanides; D007364:Intercalating Agents; D009942:Organometallic Compounds; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D004247:DNA