title: In vitro comparison of mechanical and degradation properties of equivalent absorbable suture materials from two different manufacturers.
abstract: OBJECTIVE
  To compare the mechanical, knotting, and absorption properties of 3 synthetic absorbable suture materials (polyglactin 910, polydioxanone, poliglecaprone 25) from 2 different manufacturers (Huaiyin Medical Instruments Co. Ltd. and Ethicon Inc.).
  
  
  METHODS
  Suture material samples from the same manufacturing lot for each suture type and manufacturer.
  
  
  METHODS
  Part 1: 10 samples of each suture were incubated in bovine serum and tested for ultimate load and stiffness at days 0, 1, 7, 14, 21, and 28. Part 2: 10 knotted samples were similarly evaluated, without incubation.
  
  
  RESULTS
  Huaiyin polydioxanone had a greater (P<.001) ultimate load on days 0, 1, and 7; and a consistently greater stiffness for the duration of the study, compared with the Ethicon polydioxanone. Ethicon poliglecaprone 25 had a greater ultimate load on days 0, 1, 7 (P<.001); on day 21 Huaiyin had a greater ultimate load. Ethicon poliglecaprone had greater stiffness on days 0, 1, 7 (P<.001). Ethicon polyglactin 910 had a greater (P<.001) ultimate load at all times and a greater stiffness (P<.001) at days 0, 1, 7, and 14 compared with Huaiyin polyglactin 910. Huaiyin polydioxanone and polyglactin 910 had greater knot breaking strengths than Ethicon equivalents (P<.001).
  
  
  CONCLUSIONS
  Differences in mechanical properties exist between nominally identical suture materials from different manufacturers.
authors.affiliation: North Downs Specialist Referrals, Bletchingley, UK. bpuerta@ndsr.co.uk
authors.forename: Benito
authors.initials: B
authors.lastname: de la Puerta
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Parsons
authors.forename: Edward R C
authors.initials: ER
authors.lastname: Draper
authors.forename: Alison L
authors.initials: AL
authors.lastname: Moores
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Moores
mesh_terms: D004146:Dioxanes / Q000737:chemistry; D008422:Materials Testing; D016687:Polydioxanone / Q000737:chemistry; D011091:Polyesters / Q000737:chemistry; D011098:Polyglactin 910 / Q000737:chemistry; D013537:Sutures; D013718:Tensile Strength; D013997:Time Factors
chemical_list: D004146:Dioxanes; D011091:Polyesters; D016687:Polydioxanone; D011098:Polyglactin 910; C095495:glycolide E-caprolactone copolymer