title: Mild encephalitis/encephalopathy with a reversible splenial lesion: evaluation by diffusion tensor imaging. Two case reports.
abstract: Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinico-radiological syndrome with a very particular clinical course. Three patients with MERS were evaluated by various sequences of magnetic resonance imaging with diffusion tensor imaging. Initial diffusion-weighted imaging showed reduction in the apparent diffusion coefficient values in the lesions, which completely resolved with the elimination of symptoms. However, diffusion anisotropy of the lesions showed no remarkable abnormalities in the early or delayed phases. These results may indicate that white matter architecture is preserved in both early and delayed phases in MERS.
authors.affiliation: Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki.
authors.forename: Satoru
authors.initials: S
authors.lastname: Osuka
authors.forename: Hironori
authors.initials: H
authors.lastname: Imai
authors.forename: Eiichi
authors.initials: E
authors.lastname: Ishikawa
authors.forename: Akira
authors.initials: A
authors.lastname: Matsushita
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Hiroki
authors.initials: H
authors.lastname: Nozue
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Ohto
authors.forename: Kousaku
authors.initials: K
authors.lastname: Saotome
authors.forename: Yoji
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Akira
authors.initials: A
authors.lastname: Matsumura
mesh_terms: D016880:Anisotropy; D001927:Brain Diseases / Q000209:etiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003337:Corpus Callosum / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004660:Encephalitis / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male