title: Congenital monoblastic leukemia presenting as jaundice, pleural effusion, and ascites: case report and literature review.
abstract: Congenital leukemias are a rare group of hematologic neoplasms with a wide range of clinical signs and symptoms. Here we reported a neonate presenting with jaundice, pleural effusion and ascites. The total protein and serum albumin were markedly low at 48 and 12 g/L. Computerized tomography showed the density of liver was asymmetry with several hypoechoic regions. Initial blood routine examination revealed only thrombocytopenia while blood white cells increased to 30.0×10(9)/L with 17% blast cells several days later. Bone marrow biopsy showed the proportion of blasts and promonocytes increased and she was diagnosed as acute monoblastic leukemia.
authors.affiliation: The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
authors.forename: Xiling
authors.initials: X
authors.lastname: Wu
authors.forename: Lizhong
authors.initials: L
authors.lastname: Du
authors.forename: Xiumin
authors.initials: X
authors.lastname: Wang
mesh_terms: D001201:Ascites / Q000151:congenital / Q000175:diagnosis*; D001854:Bone Marrow Cells / Q000473:pathology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007565:Jaundice / Q000151:congenital / Q000175:diagnosis*; D007948:Leukemia, Monocytic, Acute / Q000151:congenital / Q000175:diagnosis*; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D010996:Pleural Effusion / Q000151:congenital / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed