title: Collapsing glomerulopathy in an HIV-positive patient in a low-incidence belt.
abstract: Human immunodeficiency virus (HIV) involves glomerular, tubulointerstitial, and vascular compartments of the kidney. The most common glomerular lesion is HIV-associated focal segmental glomerulosclerosis (FSGS) and related mesangiopathies collectively termed HIV-associated nephropathy (HIVAN). A variety of immune-complex mediated glomerular diseases such as membranoproliferative glomerulonephritis (MPGN), IgA nephropathy, and lupus-like glomerulonephritis also occur. HIVAN is restricted to patients presenting with proteinuria and progressive reduction of renal function and with distinctive but not pathognomonic pathology (FSGS often coexisting with glomerular collapse and tubular microcystic dilatations). The worldwide incidence of collapsing glomerulopathy (CG) in HIV-positive patients is high in Americans. But in India and other Asian countries, other forms of kidney diseases are more commonly seen. We report the first case of CG in the state of Jammu and Kashmir which also happens to be a very low incidence belt for HIV.
authors.affiliation: Department of Pathology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.
authors.forename: I
authors.initials: I
authors.lastname: Naaz
authors.forename: R
authors.initials: R
authors.lastname: Wani
authors.forename: M S
authors.initials: MS
authors.lastname: Najar
authors.forename: K
authors.initials: K
authors.lastname: Banday
authors.forename: K M
authors.initials: KM
authors.lastname: Baba
authors.forename: H
authors.initials: H
authors.lastname: Jeelani