title: Feasibility of extended-coverage perfusion and dynamic computer tomography (CT) angiography using toggling-table technique on 64-slice CT.
abstract: OBJECTIVE
  The major drawbacks of brain computed tomography (CT) perfusion are limited coverage in the z-axis, radiation exposure and the use of contrast medium, all of which increase when CT angiography (CTA) is performed with double acquisitions. The purpose of this study was to investigate the feasibility of the 'toggling-table' technique using a 40-mm detector.
  
  
  METHODS
  The clinical usefulness of CT perfusion and 4D-CTA (time-resolved 3D-CTA), as well as the time taken and radiation exposure, were assessed in 14 non-ischemic patients clinically indicated for CT perfusion and CTA.
  
  
  RESULTS
  A perfusion map and 4D-CTA was successfully achieved in all patients. The total time needed for scanning and processing was approximately 30 min per examination. The 80-mm CT perfusion coverage and 4D-CTA images were advantageous for analyses of the anatomy and widely distributed lesions. The estimated effective radiation dose was 2.22 mSv, and the amount of contrast media was 40 mL.
  
  
  CONCLUSIONS
  The 'toggling-table' technique acts as a 'one-stop-shop' protocol for perfusion mapping and 4D-CTA over a wide area, following a single contrast injection and scan.
authors.affiliation: Department of Radiology, Hiroshima Kyoritsu Hospital, 2-19-6, Nakasu, Asaminami-ku, Hiroshima, 731-0121, Japan. horiguchi@hiroshimairyo.or.jp
authors.forename: Jun
authors.initials: J
authors.lastname: Horiguchi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kiura
authors.forename: Junpei
authors.initials: J
authors.lastname: Tanaka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukuda
authors.forename: Masao
authors.initials: M
authors.lastname: Kiguchi
authors.forename: Chikako
authors.initials: C
authors.lastname: Fujioka
authors.forename: Kaoru
authors.initials: K
authors.lastname: Kurisu
authors.forename: Kazuo
authors.initials: K
authors.lastname: Awai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography / Q000379:methods*; D002560:Cerebrovascular Circulation; D002648:Child; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007479:Iopamidol; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007479:Iopamidol