title: Trace elements in the hair of hemodialysis patients.
abstract: Trace element disturbance is often observed in hemodialysis patients. While trace element concentrations have been reported in blood samples from hemodialysis patients, they have not been well investigated in scalp hair. In the present study, 22 trace elemental concentrations were measured by inductively coupled plasma-atomic emission spectrometry in the scalp hair of 80 male hemodialysis patients and compared with those of 100 healthy male subjects. In hemodialysis patients, the concentrations of beryllium, arsenic, magnesium, chromium, manganese, iron, selenium, molybdenum, iodine, vanadium, and cobalt were significantly higher than those in healthy subjects, while lead, mercury, copper, germanium, and bromine were significantly lower than those in the former group. No significant differences were observed for lithium, aluminum, cadmium, zinc, boron, or nickel. There were significant positive correlations between the duration of hemodialysis and the magnesium and manganese concentrations. There was a significant negative correlation between cadmium concentration and the duration of hemodialysis. There were significant positive correlations between dialysis efficacy (Kt/V) and magnesium, manganese, zinc, and selenium concentrations. In conclusion, trace element concentrations of the scalp hair are different between hemodialysis patients and healthy subjects. Essential trace elements, such as magnesium, manganese, zinc, and selenium, may be affected by the duration of hemodialysis and Kt/V.
authors.affiliation: Department of Nephrology, Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, and Inoue Hospital, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
authors.forename: Akinobu
authors.initials: A
authors.lastname: Ochi
authors.forename: Eiji
authors.initials: E
authors.lastname: Ishimura
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Tsujimoto
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Kakiya
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Tabata
authors.forename: Katsuhito
authors.initials: K
authors.lastname: Mori
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shoji
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yasuda
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Nishizawa
authors.forename: Masaaki
authors.initials: M
authors.lastname: Inaba
mesh_terms: D000368:Aged; D000535:Aluminum / Q000032:analysis; D001151:Arsenic / Q000032:analysis; D002104:Cadmium / Q000032:analysis; D002857:Chromium / Q000032:analysis; D003035:Cobalt / Q000032:analysis; D003300:Copper / Q000032:analysis; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007501:Iron / Q000032:analysis; D008274:Magnesium / Q000032:analysis; D008297:Male; D008345:Manganese / Q000032:analysis; D008628:Mercury / Q000032:analysis; D008875:Middle Aged; D009532:Nickel / Q000032:analysis; D006435:Renal Dialysis; D012643:Selenium / Q000032:analysis; D013054:Spectrophotometry, Atomic; D014131:Trace Elements / Q000032:analysis*; D015032:Zinc / Q000032:analysis
chemical_list: D014131:Trace Elements; D002104:Cadmium; D002857:Chromium; D003035:Cobalt; D008345:Manganese; D003300:Copper; D009532:Nickel; D000535:Aluminum; D007501:Iron; D008628:Mercury; D012643:Selenium; D008274:Magnesium; D015032:Zinc; D001151:Arsenic