title: Arthropod venoms and cancer.
abstract: Many active principles produced by animals, plants and microorganisms have been employed in the development of new drugs to treat diseases such as cancer. Among the animals that produce pharmacologically active molecules capable of interfering in human cellular physiology, the highlights are venomous arthropods, such as scorpions, bees, wasps, spiders, ants and caterpillars. The substances found in the venom of these animals present great potential as anti-tumor agents. In this review, we present the main results of years of research involving the active compounds of arthropods venoms that have anti-cancer activity.
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Sarmento Leite, 245, CEP 90050-170 Porto Alegre/RS, Brazil.
authors.forename: Tiago Elias
authors.initials: TE
authors.lastname: Heinen
authors.forename: Ana Beatriz Gorini
authors.initials: AB
authors.lastname: da Veiga
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D001180:Arthropod Venoms / Q000737:chemistry / Q000494:pharmacology*; D001181:Arthropods / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000188:drug therapy*; D010449:Peptide Mapping
chemical_list: D000970:Antineoplastic Agents; D001180:Arthropod Venoms