title: Glucose-6-phosphate dehydrogenase deficiency diagnosed in an adolescent with type 1 diabetes mellitus and hemoglobin A1c discordant with blood glucose measurements.
abstract: Disorders of hemolysis reduce the exposure time of hemoglobin to glucose, resulting in a falsely low hemoglobin A1c level. This case report describes the unexpected diagnosis of glucose-6-phosphate dehydrogenase deficiency made during evaluation of discordant HbA1c and blood glucose measurements.
authors.affiliation: Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. danzig@email.chop.edu
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Danzig
authors.forename: Joanne T
authors.initials: JT
authors.lastname: Moser
authors.forename: Pattianne
authors.initials: P
authors.lastname: Belfield
authors.forename: Craig A
authors.initials: CA
authors.lastname: Alter
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications*; D003937:Diagnosis, Differential; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D008297:Male
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin