title: Antidepressant drug therapy does not affect weight loss one year after gastric bypass surgery.
abstract: BACKGROUND
  Preliminary data suggest that patients with actively treated depression should expect the same outcomes after surgery. The objective of this study was to compare weight loss 12 months after gastric bypass surgery in patients taking antidepressants before surgery (AD) versus those who were not (non-AD).
  
  
  METHODS
  IRB approval was obtained. All patients gave informed consent prior to participating in the study. Medication and weight loss histories were retrospectively reviewed in adult patients who were followed at 12 months post-surgery.
  
  
  RESULTS
  145 of 364 patients were taking antidepressants at baseline. There was no significant difference in weight loss between the AD and non-AD groups at 12 months (p > 0.05).
  
  
  CONCLUSIONS
  Taking antidepressant medication prior to gastric bypass surgery did not affect weight loss outcomes at 12 months.
authors.affiliation: Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY 12208-3492, USA. margaret.malone@acphs.edu
authors.forename: Margaret
authors.initials: M
authors.lastname: Malone
authors.forename: Sharon A
authors.initials: SA
authors.lastname: Alger-Mayer
authors.forename: John M
authors.initials: JM
authors.lastname: Polimeni
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000494:pharmacology*; D003863:Depression / Q000150:complications / Q000188:drug therapy; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors; D015431:Weight Loss / Q000187:drug effects*
chemical_list: D000928:Antidepressive Agents