title: Molecular imaging of hypoxia.
abstract: A wide variety of imaging approaches have been developed in the past few decades for monitoring tumor oxygenation and hypoxia in vivo. In particular, nuclear medicine has seen the development of several radiolabeled hypoxia markers and is the preferred method for imaging of tumor hypoxia. Hypoxia imaging is increasingly being used in the clinical setting and is progressing from a mere detection method to application in individualization of chemoradiotherapy.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: Satish K
authors.initials: SK
authors.lastname: Chitneni
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Palmer
authors.forename: Michael R
authors.initials: MR
authors.lastname: Zalutsky
authors.forename: Mark W
authors.initials: MW
authors.lastname: Dewhirst
mesh_terms: D006801:Humans; D000860:Hypoxia / Q000000981:diagnostic imaging* / Q000378:metabolism; D008920:Misonidazole; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D009389:Neovascularization, Pathologic; D009593:Nitroimidazoles; D049268:Positron-Emission Tomography; D011859:Radiography; D019275:Radiopharmaceuticals
chemical_list: D009593:Nitroimidazoles; D019275:Radiopharmaceuticals; C498052:fluoroazomycin arabinoside; D008920:Misonidazole