title: Changes in the prevalence of childhood asthma in seoul from 1995 to 2008 and its risk factors.
abstract: OBJECTIVE
  To investigate the prevalence of asthma and determine its risk factors in elementary school students in Seoul.
  
  
  METHODS
  A modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire was used to survey 4,731 elementary school students from five areas in Seoul between April and October, 2008.
  
  
  RESULTS
  In elementary school children, the lifetime and recent 12-month prevalence of wheezing were 11.7% and 5.6%, respectively. The lifetime prevalence of asthma diagnosis was 7.9%, and the recent 12-month prevalence of asthma treatment was 2.7%. Male sex (adjusted odds ratio [aOR], 1.90; 95% confidence interval [CI], 1.36-2.66), history of atopic dermatitis (AD) (aOR, 2.76; 95% CI, 1.98-3.84), history of allergic rhinitis (AR) (aOR, 3.71; 95% CI, 2.61-5.26), history of bronchiolitis before 2 years of age (aOR, 2.06; 95% CI, 1.39-3.07), use of antibiotics during infancy for >3 days (aOR, 1.88; 95% CI, 1.35-2.62), parental history of asthma (aOR, 2.83; 95% CI, 1.52-5.27), exposure to household molds during infancy (aOR, 1.84; 95% CI, 1.18-2.89), and the development or aggravation of asthma symptoms within 6 months after moving to a new house (aOR, 11.76; 95% CI, 5.35-25.86) were the independent risk factors for wheezing within 12 months.
  
  
  CONCLUSIONS
  The prevalence of wheezing and asthma in elementary school students in 2008 was similar to that in the past decade. Male sex, history of AD, history of AR, history of bronchiolitis before 2 years of age, parental asthma, use of antibiotics during infancy, exposure to molds in the house during infancy, and development or aggravation of asthma symptoms within 6 months after moving to a new house, could be risk factors for wheezing within 12 months.
authors.affiliation: Department of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Kwon
authors.forename: Byoung-Ju
authors.initials: BJ
authors.lastname: Kim
authors.forename: Younghwa
authors.initials: Y
authors.lastname: Song
authors.forename: Ju-Hee
authors.initials: JH
authors.lastname: Seo
authors.forename: Tae-Hee
authors.initials: TH
authors.lastname: Kim
authors.forename: Jinho
authors.initials: J
authors.lastname: Yu
authors.forename: Hyo Bin
authors.initials: HB
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authors.forename: So Yeon
authors.initials: SY
authors.lastname: Lee
authors.forename: Woo-Kyung
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authors.forename: Kyoung-Won
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authors.forename: Hye-Mi
authors.initials: HM
authors.lastname: Ji
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authors.initials: KE
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authors.forename: Ho
authors.initials: H
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authors.forename: Soo-Jong
authors.initials: SJ
authors.lastname: Hong