title: Coping strategies in patients after treatment for functioning or nonfunctioning pituitary adenomas.
abstract: OBJECTIVE
  Coping strategies may affect quality of life, which is decreased in patients after treatment for Cushing's disease, acromegaly, or nonfunctioning pituitary macroadenomas (NFMA). We aimed to explore coping strategies in these patients because this has never been done before.
  
  
  METHODS
  We conducted a cross-sectional study.
  
  
  METHODS
  We included patients treated for Cushing's disease (n = 42), for acromegaly (n = 80), and for NFMA (n = 61). These patients were compared with three reference populations: an a-select sample from the Dutch population (n = 712), patients with chronic pain (n = 59), and patients receiving primary care psychology services (n = 525). Furthermore, the three patient groups were compared with each other. Coping strategies were assessed by the Utrecht Coping List.
  
  
  RESULTS
  Compared with the a-select sample, patients with pituitary adenomas reported less active coping (P < 0.0001), sought less social support (P < 0.0001), and reported more avoidant coping (P = 0.008). In contrast, patients treated for pituitary adenomas reported somewhat better coping strategies than patients with chronic pain and those with psychological disease. When patients with different pituitary adenomas were compared, patients treated for Cushing's disease sought more social support than patients treated for NFMA (P = 0.035).
  
  
  CONCLUSIONS
  Patients treated for pituitary adenomas display different and less effective coping strategies compared with healthy controls. A targeted intervention might help to stimulate patients to use a more active coping strategy and to seek social support instead of an avoiding coping strategy. This might, in turn, improve their quality of life.
authors.affiliation: Department of Endocrinology and Metabolic Diseases C4-R, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands. J.Tiemensma@lumc.nl
authors.forename: Jitske
authors.initials: J
authors.lastname: Tiemensma
authors.forename: Adrian A
authors.initials: AA
authors.lastname: Kaptein
authors.forename: Alberto M
authors.initials: AM
authors.lastname: Pereira
authors.forename: Johannes W A
authors.initials: JW
authors.lastname: Smit
authors.forename: Johannes A
authors.initials: JA
authors.lastname: Romijn
authors.forename: Nienke R
authors.initials: NR
authors.lastname: Biermasz
mesh_terms: D000172:Acromegaly / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation; D000223:Adaptation, Psychological / Q000502:physiology*; D000236:Adenoma / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation* / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D047748:Pituitary ACTH Hypersecretion / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation / Q000628:therapy; D010911:Pituitary Neoplasms / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation* / Q000628:therapy*; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D055815:Young Adult