title: Sexual transmission of the hepatitis B virus among blood donors in a tertiary hospital in Nigeria.
abstract: BACKGROUND
  Hepatitis B can be spread by several routes, including sexually. This study aimed to determine the prevalence of sexual transmission of the virus among the Nigerian population.
  
  
  METHODS
  This was a prospective cross-sectional study involving 234 blood donors in a Nigerian tertiary hospital. Each prospective donor was screened for hepatitis B surface antigen using an enzyme-linked immunosorbent assay test. A structured questionnaire was used to obtain information regarding the possible routes of hepatitis B acquisition and the number of lifetime heterosexual partners. Respondents were divided into three risk groups. The data obtained was analysed, and the frequencies, percentages, means and standard deviations were obtained. The chi-square test was used to compare categorical variables, and a p-value equal or less than 0.05 was considered statistically significant.
  
  
  RESULTS
  A total of 234 respondents aged 18 to 56 years (mean 27.3 years) participated in the study. 223 were male and 11 were female. The overall seroprevalence of hepatitis B was 17.1 percent. The seroprevalence was higher among participants without sexual partners (20.6 percent) and those with multiple sexual partners (20.0 percent), but lower among those with single sexual partners (15.0 percent). A history of needle injuries, jaundice and injections from quacks were statistically significant when these risks were combined with a sexual risk for hepatitis B virus infection (p-value is less than 0.05).
  
  
  CONCLUSIONS
  Sexual transmission of hepatitis B was not found to be an important factor. Preventive strategies should include universal hepatitis B vaccination and discouraging the indiscriminate use of sharp objects and unauthorised medical practices.
authors.affiliation: Department of Medicine, Obafemi Awolowo University Teaching Hospital, PMB 5538 Ile-Ife, Osun State, Nigeria. olusegunadekanle@yahoo.co.uk
authors.forename: O
authors.initials: O
authors.lastname: Adekanle
authors.forename: D A
authors.initials: DA
authors.lastname: Ndububa
authors.forename: O O
authors.initials: OO
authors.lastname: Ayodeji
authors.forename: B
authors.initials: B
authors.lastname: Paul-Odo
authors.forename: T A
authors.initials: TA
authors.lastname: Folorunso
mesh_terms: D000293:Adolescent; D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D015229:Sexually Transmitted Diseases, Viral / Q000453:epidemiology / Q000635:transmission*; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens