title: [A successful case with CPT-11 + CDDP chemotherapy for recurrent gastric cancer of the remnant stomach].
abstract: We report a successful case with irinotecan (CPT-11 60 mg/m2) + cisplatin (CDDP 30 mg/m2) chemotherapy (once in 2 weeks) for recurrent gastric cancer of the remnant stomach. A 77-year-old man was performed a distal gastrectomy for duodenal ulcer 42 years ago. He had a total gastrectomy for gastric cancer of remnant stomach when he was at 73 years old. After the surgery, we treated this patient with S-1 mono-therapy for five courses. However, we finished this treatment for lymph-node metastases. Next we treated him with CPT-11 + CDDP. An abdominal CT revealed a CR after 6 courses. We finished this treatment after 12 courses for anemia (grade 3). After the treatment, the metastatic lymph-nodes appeared in no change. So we considered that CR was continued for 3.5 years.
authors.affiliation: Dept. of Surgery, Minoh City Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Oshima
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Makari
authors.forename: Shouhei
authors.initials: S
authors.lastname: Iijima
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kato
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Minako
authors.initials: M
authors.lastname: Hoshi
authors.forename: Takashi
authors.initials: T
authors.lastname: Doi
authors.forename: Masaaki
authors.initials: M
authors.lastname: Miyo
authors.forename: Takuya
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Aya
authors.initials: A
authors.lastname: Kato
authors.forename: Eiji
authors.initials: E
authors.lastname: Kurokawa
authors.forename: Nobuteru
authors.initials: N
authors.lastname: Kikkawa
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002945:Cisplatin / Q000008:administration & dosage; D005743:Gastrectomy; D018530:Gastric Stump; D006801:Humans; D000077146:Irinotecan; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D013274:Stomach Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin