title: F-18 FDG PET/CT provides the earliest findings of enthesitis in reactive arthritis.
abstract: A 31-year-old woman developed polyarthralgia and extension disorder of the right elbow of 2 months' duration without abdominal symptom. Laboratory findings revealed C-reactive protein 2.7 mg/dL. Anti-nuclear antibody (ANA), rheumatoid factor (RF), and anti-cyclic citrullinated peptide (CCP) antibody were negative. F-18 FDG PET/CT showed elevated pinpoint uptakes of FDG in the entheses. In contrast, MRI revealed no specific findings. Four months after PET/CT, she developed right lower abdominal pain. Colonoscopy showed abscess in ascending colon, which the initial PET/CT finding might mean early image of infective colitis. A diagnosis of early reactive arthritis was made. Treatment with antibiotics improved colitis, colonic abscess, and enthesitis after 2 months. Moreover, F-18 FDG PET/CT showed no accumulation in colon and entheses. These findings suggest that F-18 FDG PET/CT scanning allows enthesitis in the early stage of reactive arthritis, before the possible detection by the other procedures.
authors.affiliation: Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan. taniguchiy@kochi-u.ac.jp
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Taniguchi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Kumon
authors.forename: Syuichi
authors.initials: S
authors.lastname: Nakayama
authors.forename: Kaoru
authors.initials: K
authors.lastname: Arii
authors.forename: Takenao
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Shigeto
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Terada
mesh_terms: D000328:Adult; D016918:Arthritis, Reactive / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D042241:Early Diagnosis; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18