title: [Effect of suprarenal fixation on renal function in endovascular abdominal aneurysm repair patients].
abstract: OBJECTIVE
  to assess the the mid-term renal function of abdominal aortic aneurysm (AAA) patients following supra-renal endovascular repair.
  
  
  METHODS
  from March 2005 to December 2009, 290 AAA patients were included and grouped depending upon whether they had received infra-renal (IR) or supra-renal (SR) EVAR. SR was performed in 173 patients, with a mean age of (72 ± 8) years and 85.0% for male. IR was performed in 117 patients, with a mean age of (71 ± 9) years and 90.6% for male. Preoperative and 1 week, 1-, 3-, 6-, 12-month postoperative serum creatinine (Cr) and cystatin C (Cys-C) were detected. Estimated glomerular filtration rate (eGFR) were calculated by Cystatin-based formula and Cr-based Cockcroft formula. T test were used to determine statistical difference between or within groups.
  
  
  RESULTS
  all Patients received Talent or Zenith endograft. The ratio of device-used were 67/106 in SR group and 25/92 in IR group (P < 0.05). The other characteristics and operative files in two groups were well matched. Preoperative Cr and Cys-C were (82 ± 8) µmol/L and (0.89 ± 0.11) mg/L for SR group, (81 ± 11) µmol/L and (0.87 ± 0.15) mg/L for IR group, no difference between groups. Compared to preoperative renal markers within each group, Cr, Cys-C and eGFR worsening were found at 1 week and 12 months postoperative (P < 0.05). At 1 week postoperative, Cr in SR group and IR group were (98 ± 11) µmol/L and (95 ± 13) µmol/L, Cys-C were (1.01 ± 0.10) mg/L or (0.99 ± 0.10) mg/L. At 12 months postoperative, Cr in SR group and IR group were (91 ± 15) µmol/L or (90 ± 12) µmol/L, Cys-C were (1.03 ± 0.20) or (1.02 ± 0.21) mg/L. Also, Cys-C [SR: (0.93 ± 0.17) mg/L, IR: (0.92 ± 0.31) mg/L] and eGFR by Cys-C worsening were found at 6 months postoperative. There was no difference between groups in patients Cr, Cys-C and eGFR at each follow-up time interval.
  
  
  CONCLUSIONS
  the use of SR fixation was not significantly associated with mid-term postoperative renal injury.
authors.affiliation: Department of General Surgery, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China. cineplasticj@yahoo.com.cn
authors.forename: Ying-Bin
authors.initials: YB
authors.lastname: Jia
authors.forename: Yun
authors.initials: Y
authors.lastname: Shi
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Guan
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Bai-Meng
authors.initials: BM
authors.lastname: Zhang
authors.forename: Wei-Guo
authors.initials: WG
authors.lastname: Fu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D012189:Retrospective Studies; D015607:Stents