title: [Clinical observation of holmium laser enucleation of the prostate in the treatment of benign prostatic hyperplasia and overactive bladder].
abstract: OBJECTIVE
  To evaluate clinical efficacy of holmium laser enucleation of the prostate in the treatment of benign prostatic hyperplasia (BPH) and overactive bladder (OAB).
  
  
  METHODS
  From May 2007 to May 2010, a total of 37 patients diagnosed BPH and OAB were treated by holmium laser enucleation of the prostate. After a mean follow-up of 4.9 months postoperatively, indices such as International Prostate Symptom Score (IPSS), quality of life (QOL) score, maximum flow rate (Qmax), residual urine volume and video urodynamics were monitored and statistically analyzed.
  
  
  RESULTS
  The mean preoperative IPSS and QOL score were 29.6 ± 5.2 and 4.3 ± 0.9, and decreased to 4.6 ± 1.2 and 1.2 ± 1.0 postoperative. The mean Qmax was (6 ± 3) ml/s preoperative and increased to (21 ± 5) ml/s postoperative. Preoperative average residual urine volume was (167 ± 11) ml, decreased to (41 ± 18) ml after operation. During follow-up, 86.5% patients' symptoms and quality of life improved continuously, however 13.5% patients existed residual postoperative OAB symptoms.
  
  
  CONCLUSIONS
  When BPH with OAB patients exist bladder outlet obstruction, bladder outlet obstruction should be relieved first then OAB symptoms can be relieved in majority of patients, but some patients have residual symptoms.
authors.affiliation: Department of Urology, China Rehabilitation Research Center, Rehabilitation School of Capital Medical University, Beijing 100068, China.
authors.forename: Guang
authors.initials: G
authors.lastname: Fu
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Liao
authors.forename: Yang
authors.initials: Y
authors.lastname: Hu
authors.forename: Dong
authors.initials: D
authors.lastname: Li
authors.forename: Yan-He
authors.initials: YH
authors.lastname: Ju
authors.forename: Juan
authors.initials: J
authors.lastname: Wu
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Liang
authors.forename: Zong-Sheng
authors.initials: ZS
authors.lastname: Xiong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications / Q000601:surgery*; D020728:Transurethral Resection of Prostate / Q000379:methods*; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000150:complications* / Q000601:surgery