title: Shockwave lithotripsy: arterial aneurysms and vascular complications.
abstract: OBJECTIVE
  The application of shockwave lithotripsy (SWL) in patients with arterial aneurysm remains controversial, and several case reports exist in the world literature that describe both safe use and rupture. In addition, other vascular complications have been reported. The potential for hemorrhage is affected by coagulation status and antiplatelet therapy, yet little evidence exists on their interaction with SWL. We aim to review the vascular complications after SWL.
  
  
  METHODS
  A review of the world literature was performed in accordance with methodology that is defined by the Cochrane Collaboration. An Internet bibliographic search on MEDLINE was performed during May and June 2010, with additional hand-searching of references. The search terms lithotripsy, aneurysm, abdominal aortic aneurysm, pseudoaneurysm, hemorrhage, hematoma, coagulation, aspirin, clopidogrel, and warfarin were used.
  
  
  RESULTS
  In reported cases, there have been 18 patients with abdominal aortic aneurysm (AAA) who have undergone SWL. Both safe and uncomplicated treatment have been reported as well as rupture of AAA. Other vascular complications after SWL have included pseudoaneurysm, venous thrombosis, arterial stenosis, and arteriovenous fistulation. Patients with hemorrhagic risk factors can undergo SWL after correction of coagulopathy. Experimental work on animal models and human tissue has evaluated the effects of SWL on the vasculature.
  
  
  CONCLUSIONS
  There is currently no high-level evidence to suggest that SWL in the presence of arterial aneurysm is unsafe. Experimental work on ex vivo human tissue does not suggest that SWL is causative to aneurysm rupture. With the availability of CT imaging in modern clinical practice, aneurysms of the arterial tree should be identified as part of the investigation of urinary tract calculi. SWL can be safely performed in patients with AAA, but monitoring postprocedure is mandatory, along with access to emergency vascular surgery support; importantly, any onset of new pain or symptoms should be aggressively investigated by radiologic imaging in the first instance.
authors.affiliation: Department of Urology, Monklands Hospital, Airdrie, United Kingdom. georgetse@doctors.org.uk
authors.forename: George H
authors.initials: GH
authors.lastname: Tse
authors.forename: Hasan A
authors.initials: HA
authors.lastname: Qazi
authors.forename: Andrew K
authors.initials: AK
authors.lastname: Halsall
authors.forename: Sarath R K
authors.initials: SR
authors.lastname: Nalagatla
mesh_terms: D000783:Aneurysm / Q000209:etiology* / Q000503:physiopathology; D017542:Aneurysm, Ruptured / Q000209:etiology / Q000503:physiopathology; D001158:Arteries / Q000473:pathology* / Q000503:physiopathology; D001777:Blood Coagulation / Q000502:physiology; D001792:Blood Platelets / Q000502:physiology; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects*