title: CSA-enabled spin diffusion leads to MAS rate-dependent T1's at high field.
abstract: A surprisingly strong spin rate dependence of (15)N and (13)C NMR T(1) times in magic angle spinning experiments on solid peptides is demonstrated. Using a variety of isotopomers, the phenomenon is shown to be the result of chemical shift anisotropy-mediated spin diffusion. This effect has the potential to be used to detect long-range distance constraints in macromolecular systems.
authors.affiliation: Department of Chemistry, Yale University.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Fry
authors.forename: Suvrajit
authors.initials: S
authors.lastname: Sengupta
authors.forename: Van C
authors.initials: VC
authors.lastname: Phan
authors.forename: Shan
authors.initials: S
authors.lastname: Kuang
authors.forename: Kurt W
authors.initials: KW
authors.lastname: Zilm
mesh_terms: D016880:Anisotropy; D004058:Diffusion; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*