title: Chaos control of cardiac arrhythmias.
abstract: Chaos theory has shown that many disordered and erratic phenomena are in fact deterministic, and can be understood causally and controlled. The prospect that cardiac arrhythmias might be instances of deterministic chaos is therefore intriguing. We used a recently developed method of chaos control to stabilize a ouabain-induced arrhythmia in rabbit ventricular tissue in vitro. Extension of these results to clinically significant arrhythmias such as fibrillation will require overcoming the additional obstacles of spatiotemporal complexity.
authors.affiliation: Alan Garfinkel is at the Department of Medicine (Cardiology), University of California-Los Angeles, Los Angeles, CA 90024-1679 USA; the Department of Physiological Science, University of California-Los Angeles, Los Angeles, CA 90024-1679 USA.
authors.forename: A
authors.initials: A
authors.lastname: Garfinkel
authors.forename: J N
authors.initials: JN
authors.lastname: Weiss
authors.forename: W L
authors.initials: WL
authors.lastname: Ditto
authors.forename: M L
authors.initials: ML
authors.lastname: Spano