title: Pregnancy outcome after preimplantation genetic screening or natural conception in couples with unexplained recurrent miscarriage: a systematic review of the best available evidence.
abstract: The objective of this systematic review was to assess live birth rates and miscarriage rates after preimplantation genetic screening or natural conception for unexplained recurrent miscarriage. There were no randomized controlled trials or comparative studies found on this topic. Until data from randomized controlled trials become available, this review summarizes the best available evidence of the efficacy of preimplantation genetic screening vs. natural conception.
authors.affiliation: Center for Reproductive Medicine, Department of Obstetrics and Gynecology, University of Amsterdam, Amsterdam, the Netherlands. a.m.musters@amc.uva.nl
authors.forename: Anna M
authors.initials: AM
authors.lastname: Musters
authors.forename: Sjoerd
authors.initials: S
authors.lastname: Repping
authors.forename: Johanna C
authors.initials: JC
authors.lastname: Korevaar
authors.forename: Sebastiaan
authors.initials: S
authors.lastname: Mastenbroek
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Limpens
authors.forename: Fulco
authors.initials: F
authors.lastname: van der Veen
authors.forename: Mariëtte
authors.initials: M
authors.lastname: Goddijn
mesh_terms: D000026:Abortion, Habitual / Q000175:diagnosis / Q000235:genetics*; D019317:Evidence-Based Medicine; D005191:Family Characteristics; D005260:Female; D005306:Fertilization / Q000235:genetics / Q000502:physiology*; D005820:Genetic Testing / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D019836:Preimplantation Diagnosis / Q000379:methods / Q000706:statistics & numerical data*