title: Treatment of severe chromoblastomycosis with itraconazole and 5-flucytosine association.
abstract: Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of a male patient presenting a slow-growing pruriginous lesion on the limbs for 20 years, mistreated over that time, which was diagnosed and successfully treated as chromoblastomycosis. Besides the prevalence of this disease, treatment is still a clinical challenge.
authors.affiliation: Department of Infectious Diseases, Hospital Nossa Senhora da Conceição, Porto Alegre, RS, Brazil. vicente_antonello@hotmail.com
authors.forename: Vicente Sperb
authors.initials: VS
authors.lastname: Antonello
authors.forename: Marcelo Campos
authors.initials: MC
authors.lastname: Appel da Silva
authors.forename: Eduardo
authors.initials: E
authors.lastname: Cambruzzi
authors.forename: Dimas Alexandre
authors.initials: DA
authors.lastname: Kliemann
authors.forename: Breno Riegel
authors.initials: BR
authors.lastname: Santos
authors.forename: Flávio
authors.initials: F
authors.lastname: Queiroz-Telles
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002862:Chromoblastomycosis / Q000188:drug therapy* / Q000473:pathology; D004359:Drug Therapy, Combination; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D005437:Flucytosine