title: [Follow-up of two patients with mesangial IgA glomerulonephritis exposed to cadmium and organic solvents].
abstract: For several years we carried out a follow-up of two patients with IgA mesangial glomerulonephritis with antecedents of exposure to toxic substances (cadmium and organic solvents). The first case involved a 47 year old male who was diagnosed with mesangial IgA glomerulonephritis eight years ago; he had been working for twelve years as a solderer. He had used metal bars containing 25% cadmium as part of the soldering material. Very high levels of cadmium were detected in his blood and urine. The second case involved a 50 year male who was exposed to a wide number of organic dissolvents for 23 years. Three years ago he was diagnosed with a proliferative diffuse mesangial glomerulonephritis with IgA deposits; in spite of that, the patient continued working until one year ago, when was found to have a chronic stage 3 renal disease secondary to IgA nephropathy. Patients diagnosed with mesangial IgA glomerulonephritis should be kept apart from exposure to nephrotoxic substances.
authors.forename: J
authors.initials: J
authors.lastname: Fernández
authors.forename: Jaime Fernández
authors.initials: JF
authors.lastname: Colomé
authors.forename: P
authors.initials: P
authors.lastname: Sanz-Gallén
authors.forename: Pere
authors.initials: P
authors.lastname: Sanz-Gallén
authors.forename: S
authors.initials: S
authors.lastname: Nogué
authors.forename: Santiago Nogué
authors.initials: SN
authors.lastname: Xarau
mesh_terms: D002104:Cadmium / Q000633:toxicity*; D005500:Follow-Up Studies; D005920:Glomerular Mesangium; D005922:Glomerulonephritis, IGA / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D012997:Solvents / Q000633:toxicity*
chemical_list: D012997:Solvents; D002104:Cadmium