title: [The efficacy and safety of stereotactic radiotherapy for non-resectable non-small cell lung cancer].
abstract: Stereotactic radiotherapy (SRT) has recently been used for the treatment of small lung tumors. We retrospectively evaluated the efficacy and safety of SRT for non-small cell lung cancer (NSCLC) treated in our hospital. Between October 2007 and December 2009, 31 tumors of 29 patients were treated by SRT (mean age, 75 years: stage IA, n=13; stage IB, n=5; stage IIIA, n=1; stage IIIB, n=1; recurrence, n=11). All of the patients completed the treatment. In one patient who had radiation pneumonitis before SRT, a progression of pulmonary fibrosis was observed, and treated with steroid therapy. In evaluable 29 tumors of 27 patients, the recurrence rates are 11/29 (37.9%). Median progression free survival time was 8 months. The recurrence rate and median progression free survival time of stage IA and IB subgroups were 4/17 (23.5%) and 12 months, respectively. SRT is thought to be a safe and effective treatment for stage I NSCLC. For patients with stage I NSCLC, SRT can be a complemental therapy for surgical resection.
authors.affiliation: Dept. of Respiratory and Medical Oncology, Gifu Municipal Hospital.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Futamura
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Sawa
authors.forename: Akane
authors.initials: A
authors.lastname: Horiba
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishiguro
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Yoshida
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Iida
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Marui
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016634:Radiosurgery; D012189:Retrospective Studies