title: Perinatal outcomes associated with maternal hypertensive disorders of pregnancy in a developing country.
abstract: OBJECTIVE
  To determine adverse perinatal outcomes that portend neuro-developmental problems in the offspring of mothers with hypertensive disorders of pregnancy (HDP) in a low-income country.
  
  
  METHODS
  A cross-sectional study of surviving mother-infant pairs in southwest Nigeria.
  
  
  RESULTS
  Of 3491 mothers enrolled, 216 (6.2%) were diagnosed with HDP comprising chronic hypertension (4.6%), pregnancy-induced hypertension (55.6%), pre-eclampsia (7.4%), and eclampsia (32.4%). HDP was associated with an elevated risk of preterm birth (OR: 3.30), low birth weight (OR: 4.68), fetal growth restriction (OR: 2.94), and low Apgar scores at 1 minute (OR: 2.99) and 5 minutes (OR: 2.08) but had a protective effect on fetal distress (OR: 0.25).
  
  
  CONCLUSIONS
  Adverse perinatal outcomes of HDP may place surviving newborns in poorly resourced countries at risk of neuro-developmental deficits.
authors.affiliation: Maternal and Child Health Unit, Department of Community Health and Primary Care, College of Medicine, University of Lagos, Surulere, Lagos, Nigeria. boolusanya@aol.com
authors.forename: Bolajoko O
authors.initials: BO
authors.lastname: Olusanya
authors.forename: Olumuyiwa A
authors.initials: OA
authors.lastname: Solanke
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003906:Developing Countries / Q000706:statistics & numerical data*; D002658:Developmental Disabilities / Q000453:epidemiology*; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology*; D007231:Infant, Newborn; D009549:Nigeria / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D055815:Young Adult