title: Congener profile, occurrence and estimated dietary intake of dioxins and dioxin-like PCBs in foods marketed in the Region of Valencia (Spain).
abstract: During 2006-2008, a monitoring program was conducted on 29 target compounds, including PCDD/Fs and dl-PCBs, comprising 150 randomly collected individual food samples marketed in the Region of Valencia, Spain, grouped into 8 categories (vegetables, cereals, fats and oils, eggs, milk and dairy products, fish products, meat and meat products and fish oil). For PCDD/Fs, the highest frequency of detection corresponds to 1,2,3,4,6,7,8-HpCDD, OCDD, 2,3,4,7,8-PeCDF; and PCBs 118, 105 and 156 were the more frequent dl-PCBs. The food groups presenting higher contamination, expressed as toxic equivalents (WHO-TEQs), were fish oil (6.38 pg WHO-TEQ g(-1)fat), fish (1.21 pg WHO-TEQ g(-1)w.w.) and milk and dairy products (0.90 pg WHO-TEQ g(-1)fat). Of all analysed samples, only two fish oils presented levels higher than the EU limits for total WHO-TEQ. The average PCDD/Fs and dl-PCBs intakes were estimated as 2.86 pg WHO-TEQ kg(-1)b.w.d(-1) and 4.58 pg WHO-TEQ kg(-1)b.w.d(-1), for adults and children, respectively, using the deterministic method for chronic exposure. The main contributors to total intake for adults were fish (59%), milk and dairy products (19%), and fat and oils (9%). The average daily intake for adults (2.86 pg WHO-TEQ kg(-1)b.w.d(-1)) is within range of TDI recommended by the WHO (1-4 pg WHO-TEQ kg(-1)b.w.d(-1)), and slightly above the TWI and PTMI adopted by SCF and JECFA respectively.
authors.affiliation: Public Health Research Center (CSISP), 21 Avda Cataluña, 46020 Valencia, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Marin
authors.forename: P
authors.initials: P
authors.lastname: Villalba
authors.forename: J
authors.initials: J
authors.lastname: Diaz-Ferrero
authors.forename: G
authors.initials: G
authors.lastname: Font
authors.forename: V
authors.initials: V
authors.lastname: Yusà
mesh_terms: D000328:Adult; D003611:Dairy Products / Q000032:analysis; D004032:Diet / Q000706:statistics & numerical data; D004147:Dioxins / Q000008:administration & dosage* / Q000032:analysis / Q000737:chemistry; D004531:Eggs / Q000032:analysis; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000008:administration & dosage* / Q000032:analysis / Q000737:chemistry; D004787:Environmental Pollution / Q000706:statistics & numerical data; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis / Q000706:statistics & numerical data*; D006801:Humans; D008460:Meat / Q000032:analysis; D010945:Plants, Edible / Q000737:chemistry; D011078:Polychlorinated Biphenyls / Q000008:administration & dosage* / Q000032:analysis / Q000737:chemistry; D013030:Spain
chemical_list: D004147:Dioxins; D004785:Environmental Pollutants; D011078:Polychlorinated Biphenyls