title: The role of antithrombotics in secondary stroke prevention.
abstract: Antithrombotic therapy plays a key role in secondary ischemic stroke prevention. A multitude of antithrombotic agents exist with varying pharmacologic, efficacy, and safety profiles. In this review, the authors discuss the mechanisms of antithrombotic therapy, summarize the data on commonly used agents, and introduce emerging antithrombotic medications.
authors.affiliation: Section of Cerebrovascular Disease and Neurocritical Care, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA. mlazzaro2@gmail.com
authors.forename: Marc A
authors.initials: MA
authors.lastname: Lazzaro
authors.forename: Konark
authors.initials: K
authors.lastname: Malhotra
authors.forename: Yousef M
authors.initials: YM
authors.lastname: Mohammad
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D000077144:Clopidogrel; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D055502:Secondary Prevention; D020521:Stroke / Q000517:prevention & control*; D013927:Thrombosis / Q000517:prevention & control; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D016861:Cyclooxygenase Inhibitors; D005343:Fibrinolytic Agents; D010726:Phosphodiesterase Inhibitors; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine