title: Selective responses in right inferior frontal and supramarginal gyri differentiate between observed movements of oneself vs. another.
abstract: The fact that inferior frontal (IFg) and supramarginal (SMg) gyri respond to both self-generated and observed actions has been interpreted as evidence for a perception-action linking mechanism (mirroring). Yet, the brain readily distinguishes between percepts generated by one's own movements vs. those of another. Do IFg and/or SMg respond differentially to these visual stimuli even when carefully matched? We used BOLD fMRI to address this question as participants made repetitive bimanual hand movements while viewing either live visual feedback or perceptually similar, pre-recorded video of an actor. As expected, bilateral IFg and SMg increased activity during both conditions. However, right SMg and IFg responded differentially during live visual feedback vs. matched recordings. These mirror system areas may distinguish self-generated percepts by detecting subtle spatio-temporal differences between predicted and actual sensory feedback and/or visual and somatosensory signals.
authors.affiliation: 1227 Department of Psychology, University of Oregon, Eugene, OR 97403-5288, USA. Electronic address: macuga@uoregon.edu.
authors.forename: Kristen L
authors.initials: KL
authors.lastname: Macuga
authors.affiliation: 1227 Department of Psychology, University of Oregon, Eugene, OR 97403-5288, USA; Lewis Center for Neuroimaging, University of Oregon, Eugene, OR 97403, USA. Electronic address: shfrey@uoregon.edu.
authors.forename: Scott H
authors.initials: SH
authors.lastname: Frey
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D056228:Feedback, Sensory / Q000502:physiology*; D005260:Female; D006225:Hand; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009068:Movement / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation / Q000379:methods; D011597:Psychomotor Performance; D012649:Self Concept; D014796:Visual Perception; D055815:Young Adult
chemical_list: D010100:Oxygen