title: A facile process for the asymmetric synthesis of β-trifluoromethylated β-amino ketones via addition of ketone enolates to sulfinylimine.
abstract: An efficient method for the asymmetric synthesis of β-trifluoromethylated β-amino ketones via addition of ketone-derivative enolates to trifluoromethylated sulfinylimine has been developed, with good chemical yields and excellent diastereoselectivities. This practical method was also proved to be suitable for large-scale preparation.
authors.affiliation: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
authors.forename: Haibo
authors.initials: H
authors.lastname: Mei
authors.forename: Yiwen
authors.initials: Y
authors.lastname: Xiong
authors.forename: Jianlin
authors.initials: J
authors.lastname: Han
authors.forename: Yi
authors.initials: Y
authors.lastname: Pan