title: Recurrent laryngeal papillomatosis: successful treatment with human papillomavirus vaccination.
abstract: The authors describe the case of a 5-year-old girl with recurrent laryngeal papillomatosis (RLP) due to human papillomavirus (HPV) type 11, who required frequent surgical treatment. Complete recovery occurred after HPV vaccination (Gardasil). Confirmed remission of RLP has continued during the 17 months of follow-up since vaccination. The authors conclude that HPV vaccination may represent a new therapeutic option in this situation.
authors.affiliation: Department of Paediatric Oncology, University Children's Hospital Brno, Cernopolni 9, Brno, Czech Republic. pmudry@seznam.cz
authors.forename: Peter
authors.initials: P
authors.lastname: Mudry
authors.forename: Martin
authors.initials: M
authors.lastname: Vavrina
authors.forename: Pavel
authors.initials: P
authors.lastname: Mazanek
authors.forename: Michaela
authors.initials: M
authors.lastname: Machalova
authors.forename: Jiri
authors.initials: J
authors.lastname: Litzman
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Sterba
mesh_terms: D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D006801:Humans; D007822:Laryngeal Neoplasms / Q000517:prevention & control / Q000601:surgery / Q000821:virology; D010212:Papilloma / Q000517:prevention & control / Q000601:surgery / Q000821:virology; D053918:Papillomavirus Vaccines; D055502:Secondary Prevention
chemical_list: D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D053918:Papillomavirus Vaccines