title: [Drug therapy options for oligoasthenoteratozoospermia syndrome].
abstract: Medical treatment of oligoasthenoteratozoospermia (OAT) syndrome includes many different treatment concepts. The targeted causes in the treatment of OAT syndrome are either hormonal, as for example hypothalamic, pituary, or, seldom, hyperprolactinemic disturbances, or acute or chronic urogenital infections, as well as ejaculatory disorders. Often no pathogenic reason for OAT syndrome can be found and targeted. Most treatment concepts in the past tried to improve sperm quality. Administration of antiestrogens, antioxidants, hormones, and micronutrients has been tried and used to improve sperm quality. The present article provides an overview of current medical treatment options for OAT syndrome, including former unsuccessful treatment concepts. The article furthermore sketches out potential treatment options, which might be available in the future.
authors.affiliation: Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Campus Großhadern, Klinikum der Universität München, Marchioninistraße 15, 81377 München, Deutschland. matthias.trottmann@uro.med.uni-muenchen.de
authors.forename: M
authors.initials: M
authors.lastname: Trottmann
authors.forename: F M
authors.initials: FM
authors.lastname: Köhn
authors.forename: M
authors.initials: M
authors.lastname: Dickmann
authors.forename: C G
authors.initials: CG
authors.lastname: Stief
authors.forename: A J
authors.initials: AJ
authors.lastname: Becker
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use*; D053627:Asthenozoospermia / Q000188:drug therapy*; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy*; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D013577:Syndrome; D013733:Testicular Diseases / Q000188:drug therapy*; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D000975:Antioxidants