title: [Properties of single L-type Ca2+ channels in hypothalamic neurons of newborn rats].
abstract: OBJECTIVE
  To investigate the characteristics of single L-type Ca2+ channels in hypothalamic neurons.
  
  
  METHODS
  The cell-attached patch-clamp technique and acute cell isolation technique were used.
  
  
  RESULTS
  (1) L-type Ca2+ channels opened throughout an 768 ms long voltage pulse. (2) The averaged open-time constant was 0.28 ms(tau0), two closed-time constants were 2.91 (tau(c1)) and 53.22 ms(tau(c2)). (3) The conductance was (29.5 +/- 3.1) pS and (4) Bay K 8644 increased the open probability by prolonging the mean open time to 1.61 ms.
  
  
  CONCLUSIONS
  L-type Ca2+ channel existed in hypothalamic neurons, with the similar properties to Ca2+ currents as previously reported, but showed its own peculiarity.
authors.affiliation: Department of High Temperature, First Military Medical University, Guangzhou 510515, China.
authors.forename: Q J
authors.initials: QJ
authors.lastname: Fu
authors.forename: F
authors.initials: F
authors.lastname: Zou
authors.forename: C Q
authors.initials: CQ
authors.lastname: Cai
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D020746:Calcium Channels, L-Type / Q000502:physiology*; D007031:Hypothalamus / Q000166:cytology* / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D018408:Patch-Clamp Techniques; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D020746:Calcium Channels, L-Type