title: [Two cases of lymph node recurrence after endoscopic mucosal resection of esophageal cancer].
abstract: Here, we reported two cases of lymph node recurrence after endoscopic mucosal resection of esophageal cancer. Case 1: A patient was a 49-year-old man. Endoscopic mucosal resection (EMR) was performed to the 0-IIc type esophageal cancer in October 2005. The pathological findings were moderately differentiated squamous cell carcinoma, pT1b-SM3, ly0, and v0. Therefore, additional therapy of definitive chemoradiation was conducted. However, he complained a difficulty in swallowing in June 2007 and computed tomography (CT) revealed a lymph node measuring 4 cm in diameter at the right side of cardia ( #1). Therefore, a radical operation to the lymph node recurrence was performed in August 2007. Pathological findings revealed metastases of cancer were not only in #1 LN but also in #8a. Unfortunately, the patient died on the 37th day after the operation due to a respiratory failure and anastomotic leakage. Case 2: A patient was a 68-year-old man. EMR was performed to the 0-IIa type esophageal cancer in August 2006. The pathological findings were poorly differentiated squamous cell carcinoma, pT1a-MM, ly0, v0. Therefore, adjuvant chemotherapy was added. However, in February 2009, a follow-up CT showed a metastatic lymph node measuring 2 cm in diameter at the right side of cardia (#1) and a radical operation was performed in June 2009. Pathological findings revealed the metastatic lymph nodes were at the right side of cardia (#1) and middle thoracic paraesophagus (#108).
authors.affiliation: Dept. of Surgical Oncology, Osaka City University Graduate School of Medicine.
authors.forename: Junya
authors.initials: J
authors.lastname: Morimoto
authors.forename: Naoshi
authors.initials: N
authors.lastname: Kubo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Masaichi
authors.initials: M
authors.lastname: Ohira
authors.forename: Kazuya
authors.initials: K
authors.lastname: Muguruma
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Sawada
authors.forename: Nobuya
authors.initials: N
authors.lastname: Yamada
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yashiro
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Yukio
authors.initials: Y
authors.lastname: Nishiguchi
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D004945:Esophagoscopy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000601:surgery; D009364:Neoplasm Recurrence, Local