title: Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11.
abstract: The 2010/11 winter influenza season is underway in the United Kingdom, with co-circulation of influenza A(H1N1)2009 (antigenically similar to the current 2010/11 vaccine strain), influenza B (mainly B/Victoria/2/87 lineage, similar to the 2010/11 vaccine strain) and a few sporadic influenza A(H3N2) viruses. Clinical influenza activity has been increasing. Severe illness, resulting in hospitalisation and deaths, has occurred in children and young adults and has predominantly been associated with influenza A(H1N1)2009, but also influenza B viruses.
authors.affiliation: Health Protection Agency, Centre for Infections, London, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Ellis
authors.forename: M
authors.initials: M
authors.lastname: Galiano
authors.forename: R
authors.initials: R
authors.lastname: Pebody
authors.forename: A
authors.initials: A
authors.lastname: Lackenby
authors.forename: C
authors.initials: C
authors.lastname: Thompson
authors.forename: A
authors.initials: A
authors.lastname: Bermingham
authors.forename: E
authors.initials: E
authors.lastname: McLean
authors.forename: H
authors.initials: H
authors.lastname: Zhao
authors.forename: S
authors.initials: S
authors.lastname: Bolotin
authors.forename: O
authors.initials: O
authors.lastname: Dar
authors.forename: J M
authors.initials: JM
authors.lastname: Watson
authors.forename: M
authors.initials: M
authors.lastname: Zambon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000956:Antigens, Viral / Q000235:genetics; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D005838:Genotype; D006760:Hospitalization; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D009981:Influenza B virus / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D007252:Influenza Vaccines / Q000276:immunology; D007251:Influenza, Human / Q000175:diagnosis / Q000401:mortality* / Q000517:prevention & control / Q000821:virology*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D010802:Phylogeny; D012621:Seasons; D018571:Sentinel Surveillance; D017422:Sequence Analysis, DNA; D012720:Severity of Illness Index; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000956:Antigens, Viral; D007252:Influenza Vaccines