title: Intracranial venous pressure is normal in patients with multiple sclerosis.
abstract: Chronic cerebrospinal venous insufficiency (CCSVI) has been postulated as a cause for multiple sclerosis (MS). Venous pressure assessments have not been made. Intracranial venous pressure was assessed using ophthalmodynamometry in 29 MS patients and compared with 28 healthy controls and 19 cases with elevated intracranial pressure (ICP). MS and control subjects had normal venous pressures (mean 15.5 resp. 15.1 cmHg). Only cases with intracranial pressure pathology had elevated venous pressures (mean 28.8 cmHg). There is no evidence of an increased intracranial venous pressure in MS patients.
authors.affiliation: Augustahospital Anholt, Isselburg-Anholt, Germany.
authors.forename: Rolf
authors.initials: R
authors.lastname: Meyer-Schwickerath
authors.forename: Christian
authors.initials: C
authors.lastname: Haug
authors.forename: Annette
authors.initials: A
authors.lastname: Hacker
authors.forename: Frauke
authors.initials: F
authors.lastname: Fink
authors.forename: Dietmar
authors.initials: D
authors.lastname: Seidel
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Hartung
authors.forename: Michael R
authors.initials: MR
authors.lastname: Haupts
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002496:Central Venous Pressure; D002550:Cerebral Veins / Q000503:physiopathology*; D005260:Female; D005858:Germany; D006801:Humans; D019586:Intracranial Hypertension / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009884:Ophthalmodynamometry