title: Hereditary spherocytosis with leg ulcers healing after splenectomy.
abstract: Hereditary spherocytosis (HS) is a familial hemolytic disorder with marked heterogeneity. A refractory chronic leg ulcer is an uncommon complication of HS, reported in fewer than two percent of patients. We present the case of a 28-year-old man who was suffering from a leg ulcer and was unresponsive to treatment of two years' duration with various conservative modalities. He had been suffering from repeated attacks of jaundice, pallor, and splenomegaly since he was 10 years old. Upon admission, physical and laboratory findings revealed moderate HS. However, complete clearance of the leg ulcer was not achieved until two months after a splenectomy.
authors.affiliation: Department of Internal Medicine, Hassan II Hospital, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, Fes, Morocco. rabhisamira@gmail.com
authors.forename: Samira
authors.initials: S
authors.lastname: Rabhi
authors.forename: Hind
authors.initials: H
authors.lastname: Benjelloune
authors.forename: Mariam
authors.initials: M
authors.lastname: Meziane
authors.forename: Moncef
authors.initials: M
authors.lastname: Amrani
authors.forename: Rhizlane
authors.initials: R
authors.lastname: Berrady
authors.forename: Ouafae
authors.initials: O
authors.lastname: Mikou
authors.forename: Fatima Zohra
authors.initials: FZ
authors.lastname: Mernissi
authors.forename: Wafaa
authors.initials: W
authors.lastname: Bono
mesh_terms: D000328:Adult; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D013103:Spherocytosis, Hereditary / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013156:Splenectomy