title: Correlation Between Hump Dimensions and Curve Severity in Idiopathic Scoliosis Before and After Conservative Treatment.
abstract: METHODS
  Prospective study in 150 consecutive outpatients affected by adolescent idiopathic scoliosis (AIS).
  
  
  OBJECTIVE
  The purposes were to (1) identify a correlation between hump dimensions and the severity of scoliotic curve, and (2) evaluate how the treatment influenced the main parameters of scoliosis.
  
  
  BACKGROUND
  The existence of a relationship between clinical deformities and curve severity in AIS is still debated. Furthemore, only a few studies have investigated the effectiveness of conservative treatment for idiopathic scoliosis taking into account both clinical and radiologic factors.
  
  
  METHODS
  150 consecutive outpatients (mean age 12.8 ± 1.9 years) affected by AIS were subjected to conservative brace-based treatment. 134 participants completed the treatment protocol. Two parameters were considered to evaluate the treatment progress: the hump and the Cobb angle. Measurements were determined at the beginning and the end of treatment. Statistical analyses were performed in the whole sample and after dividing the study participants into 4 subgroups: patients with lumbar (n = 66) or thoracic curves (n = 68), patients ranging in age between 6 and 13 years (n = 89) and patients ≥ 14 years of age (n = 45).
  
  
  RESULTS
  A positive correlation was detected between the hump dimension and curve severity at the beginning and the end of treatment, except for lumbar curves at baseline. The deformity was effectively corrected by the orthotic treatment (Cobb angle: 29.4 ± 8.5° at baseline and 19.3 ± 9.8° at the end of treatment; hump severity: 11.6 ± 5.6 mm at baseline and 6.2 ± 4.6 mm at the end). In addition, our data indicate that the hump correction is more evident than that of the curve registered in Cobb degrees.
  
  
  CONCLUSIONS
  A significant correlation exists between the hump dimension and curve severity both at the beginning and the end of treatment, except for lumbar curves at baseline. The brace treatment confirmed its effectiveness in arresting the deformity progression and inducing a remodeling both of the scoliotic curve and the hump.
authors.affiliation: Department of Orthopaedics and Traumatology, Children's Hospital Bambino Gesù, Institute of Scientific Research, P.zza S. Onofrio 4 -00165 Rome, Italy.
authors.forename: Angelo Gabriele
authors.initials: AG
authors.lastname: Aulisa
authors.affiliation: Department of Orthopaedics and Traumatology, Children's Hospital Bambino Gesù, Institute of Scientific Research, P.zza S. Onofrio 4 -00165 Rome, Italy.|University of Cassino, Strada Folcare, 4 - 03043 Cassino (FR), Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Guzzanti
authors.affiliation: Department of Orthopaedics, Catholic University of the Sacred Heart, University Hospital "Agostino Gemelli", L.go F. Vito, 1 - 00168 Rome, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Perisano
authors.affiliation: Department of Orthopaedics, Catholic University of the Sacred Heart, University Hospital "Agostino Gemelli", L.go F. Vito, 1 - 00168 Rome, Italy.|Department of Aging and Geriatric Research, Institute on Aging, Division of Biology of Aging, University of Florida, Gainesville, FL 32610-0143, USA.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Marzetti
authors.affiliation: Department of Orthopaedics, Catholic University of the Sacred Heart, University Hospital "Agostino Gemelli", L.go F. Vito, 1 - 00168 Rome, Italy.
authors.forename: Amerigo
authors.initials: A
authors.lastname: Menghi
authors.affiliation: Department of Orthopaedics and Traumatology, Children's Hospital Bambino Gesù, Institute of Scientific Research, P.zza S. Onofrio 4 -00165 Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Giordano
authors.affiliation: Department of Orthopaedics, Catholic University of the Sacred Heart, University Hospital "Agostino Gemelli", L.go F. Vito, 1 - 00168 Rome, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Aulisa
mesh_terms: D000293:Adolescent; D001915:Braces; D002648:Child; D000072700:Conservative Treatment; D018450:Disease Progression; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D011446:Prospective Studies; D012600:Scoliosis / Q000175:diagnosis / Q000628:therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome