title: Inhibition of electrochemical fouling against biomolecules on a diamond-like carbon electrode.
abstract: An anti-fouling ability of diamond-like carbon (DLC) electrodes to biological macromolecules has been investigated from a decrease in the electrochemical redox current of Fe(CN)(6)(4-/3-), used as a redox marker. A DLC electrode and a glassy carbon (GC) electrode were immersed in a solution containing bovine serum albumin (BSA) or DNA. The GCs treated with biological macromolecules gave rise to a significant decrease in the currents, while there was no signal decreases from the treated DLCs. The signals from the DLCs remain essentially unchanged for at least 24 h at a 10 mg/mL concentration level of BSA.
authors.affiliation: Graduate School of Material Science, University of Hyogo, 3-2-1 Kouto, Kamigori, Ako-gun, Hyogo 678-1297, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Goto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yasukawa
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kanda
authors.forename: Shinji
authors.initials: S
authors.lastname: Matsui
authors.forename: Fumio
authors.initials: F
authors.lastname: Mizutani
mesh_terms: D000818:Animals; D057219:Biofouling / Q000517:prevention & control*; D002417:Cattle; D004247:DNA / Q000032:analysis / Q000737:chemistry*; D018130:Diamond / Q000737:chemistry*; D004553:Electric Conductivity; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D005292:Ferricyanides / Q000737:chemistry; D005399:Fishes; D006801:Humans; D046911:Macromolecular Substances / Q000737:chemistry; D008297:Male; D010084:Oxidation-Reduction; D012710:Serum Albumin, Bovine / Q000032:analysis / Q000737:chemistry*; D013094:Spermatozoa / Q000737:chemistry
chemical_list: D005292:Ferricyanides; D046911:Macromolecular Substances; D012710:Serum Albumin, Bovine; D018130:Diamond; D004247:DNA