title: [A case of cholangiocellular carcinoma accompanied with peripheral blood eosinophilia which improved by removal of the hepatic tumor].
abstract: We present a case of cholangiocellular carcinoma accompanied with moderate blood eosinophilia. A 65-year-old man was admitted to our hospital because of widely spread skin eruption like urticaria with severe itching. Laboratory findings on admission showed leukocytosis (WBC 10,600/mm3) with moderate eosinophilia (eosinophils 3,678/mm3). Stool examination for ova and parasites was negative. Bone marrow aspiration revealed almost normal appearance. Chest X-ray was normal. Abdominal CT scan revealed a hepatic tumor (6.8 cm in diameter) in the left hepatic lobe. Needle biopsy of the hepatic tumor revealed an adenocarcinoma. We performed left hepatectomy with lymph node dissection without a bile duct reconstruction. The tumor was mass forming type accompanied with intra bile ductal growth in macroscopically. Pathological diagnosis was cholangiocellular carcinoma. After removal of the hepatic tumor, peripheral blood eosinophil counts fell down and cutaneous lesion disappeared immediately. Since the surgery, the patient had no sign of recurrence for 4 years.
authors.affiliation: Dept. of Surgery, Ube Industries, LTD., Central Hospital.
authors.forename: Sakurao
authors.initials: S
authors.lastname: Hiraki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Matsukuma
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nagashima
authors.forename: Toru
authors.initials: T
authors.lastname: Kawaoka
authors.forename: Shintaro
authors.initials: S
authors.lastname: Fukuda
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000150:complications* / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000601:surgery; D018281:Cholangiocarcinoma / Q000150:complications* / Q000601:surgery; D004802:Eosinophilia / Q000209:etiology*; D006498:Hepatectomy; D006801:Humans; D008297:Male; D014581:Urticaria / Q000209:etiology