title: Disparate antiviral responses in Molluscum contagiosum virus-induced skin lesions.
abstract: Molluscum contagiosum virus (MCV) is a poxvirus that causes tumor-like skin lesions. New evidence indicates that plasmacytoid dendritic cells, type I interferon production, and interferon-induced dendritic cells have prominent roles in anti-MCV responses, and these features characterize the inflammatory response in lesions that will likely undergo spontaneous regression.
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Swiecki
authors.forename: Marco
authors.initials: M
authors.lastname: Colonna
mesh_terms: D000818:Animals; D001706:Biopsy; D003713:Dendritic Cells / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000378:metabolism / Q000473:pathology; D007370:Interferon Type I / Q000378:metabolism; D008976:Molluscum Contagiosum / Q000473:pathology* / Q000821:virology*; D008977:Molluscum contagiosum virus / Q000302:isolation & purification*; D012867:Skin / Q000378:metabolism / Q000473:pathology* / Q000821:virology*
chemical_list: D007370:Interferon Type I