title: [Three-dimensional finite element model of thoracolumbar spine with osteoporotic vertebral compression fracture].
abstract: OBJECTIVE
  To build a three-dimensional finite element model of thoracolumbar spine with osteoporotic vertebral compression fracture (OVCF) and analyze its biomechanical change.
  
  
  METHODS
  The T10-L2 segment data were obtained from computed tomography (CT) scans of an elderly female with a single T12 OVCF. A three-dimensional finite element model of thoracolumbar spine was constructed with the MIMICS and ABAQUS software. The model was composed of bony vertebrae, articulating facets, intervertebral disc and associated ligaments. The basic stress analysis of T10-L2 motion segment was made for different material properties of bone, ligaments and facet joints contacting frictional property. The stress on the annulus fiber, nucleus pulposus, endplate and facet joints under axial pressure (0.3 MPa, 1.0 MPa, 4.0 MPa) were analyzed.
  
  
  RESULTS
  A three-dimensional finite element model of human T12-L2 motion segment had 617468 elements. And the stress was higher in vertebral body than posterior structure. The distribution of pressure stresses in intervertebral disc was asymmetrical. The stress increased with a rising axial pressure.
  
  
  CONCLUSIONS
  3D finite element model of thoracolumbar OVCF and adjacent segments are successfully established. The results of stress analysis are both feasible and reliable.
authors.affiliation: Department of Orthopedics, Beijing Friendship hospital, Capital Medical University, Beijing 100050, China. feiqi@medmail.com.cn
authors.forename: Qi
authors.initials: Q
authors.lastname: Fei
authors.forename: Qiu-jun
authors.initials: QJ
authors.lastname: Li
authors.forename: Yong
authors.initials: Y
authors.lastname: Yang
authors.forename: Dong
authors.initials: D
authors.lastname: Li
authors.forename: Hai
authors.initials: H
authors.lastname: Tang
authors.forename: Jin-jun
authors.initials: JJ
authors.lastname: Li
authors.forename: Bing-qiang
authors.initials: BQ
authors.lastname: Wang
authors.forename: Yi-peng
authors.initials: YP
authors.lastname: Wang
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D005260:Female; D020342:Finite Element Analysis; D050815:Fractures, Compression / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000293:injuries; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000293:injuries