title: Tricalysionoside A, a megastigmane gentiobioside, sulfatricalysines A-F, and tricalysiosides X-Z, ent-kaurane glucosides, from the leaves of Tricalysia dubia.
abstract: Further isolation work on the water-soluble fraction of a MeOH extract of Tricalysia dubia afforded one new megastigmane gentiobioside, named tricalysionoside A (1), and three sulfates, named sulfatricalysines A-C (2-4). Extensive isolation work on the 1-BuOH-soluble fraction of a MeOH extract of T. dubia yielded sulfatricalysines D-F (5-7) and three new ent-kaurane glucosides, named tricalysiosides X-Z (8-10). The structures of the new compounds were elucidated by analyses of one- and two-dimensional NMR spectroscopic data. The absolute stereochemistry of tricalysionoside A (1) was established by modified Mosher's method.
authors.affiliation: Graduate School of Biomedical Sciences, Hiroshima University, Minami, Hiroshima, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Shitamoto
authors.forename: Sachiko
authors.initials: S
authors.lastname: Sugimoto
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Matsunami
authors.forename: Hideaki
authors.initials: H
authors.lastname: Otsuka
authors.forename: Takakazu
authors.initials: T
authors.lastname: Shinzato
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Takeda
mesh_terms: D003512:Cyclohexanones / Q000737:chemistry*; D045786:Diterpenes, Kaurane / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D045792:Norisoprenoids / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; D045786:Diterpenes, Kaurane; D005960:Glucosides; D045792:Norisoprenoids; C413264:megastigmane