title: Intraoperative PaO2 is not related to the development of surgical site infections after major cardiac surgery.
abstract: BACKGROUND
  The perioperative use of high inspired oxygen fraction (FIO2) for preventing surgical site infections (SSIs) has demonstrated a reduction in their incidence in some types of surgery however there exist some discrepancies in this respect. The aim of this study was to analyze the relationship between PaO2 values and SSIs in cardiac patients.
  
  
  METHODS
  We designed a prospective study in which 1,024 patients undergoing cardiac surgery were analyzed.
  
  
  RESULTS
  SSIs were observed in 5.3% of patients. There was not significant difference in mortality at 30 days between patients with and without SSIs. In the uni and multivariate analysis no differences in function of the inspired oxygen fraction administrated were observed.
  
  
  CONCLUSIONS
  We observed that the PaO2 in adult cardiac surgery patients was not related to SSI rate.
authors.forename: Juan
authors.initials: J
authors.lastname: Bustamante
authors.forename: Eduardo
authors.initials: E
authors.lastname: Tamayo
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Alvarez
authors.forename: Israel
authors.initials: I
authors.lastname: García-Cuenca
authors.forename: Santiago
authors.initials: S
authors.lastname: Flórez
authors.forename: Inma
authors.initials: I
authors.lastname: Fierro
authors.forename: José Ignacio
authors.initials: JI
authors.lastname: Gómez-Herreras
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D011379:Prognosis; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000209:etiology* / Q000378:metabolism / Q000517:prevention & control
chemical_list: D010100:Oxygen