title: Identification of novel nuclear protein interactions with the N-terminal part of filamin A.
abstract: Since certain missense mutations in the N-terminal part of filamin A (FLNA) cause inherited skeletal malformation, we screened for proteins that bind to this part of FLNA. We identified two nuclear proteins that are specifically associated with the N-terminal region of FLNA. This suggests more extensive nuclear function of filamin than expected.
authors.affiliation: Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka 599-8531, Japan.
authors.forename: Hao
authors.initials: H
authors.lastname: Qiu
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Nomiyama
authors.forename: Keisuke
authors.initials: K
authors.lastname: Moriguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukada
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugimoto
mesh_terms: D000818:Animals; D003285:Contractile Proteins / Q000378:metabolism*; D064448:Filamins; D015723:Gene Library; D006801:Humans; D051379:Mice; D008840:Microfilament Proteins / Q000378:metabolism*; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D011485:Protein Binding
chemical_list: D003285:Contractile Proteins; D064448:Filamins; D008840:Microfilament Proteins; D009687:Nuclear Proteins