title: [Two cases of gastric endocrine cell carcinoma].
abstract: Gastric endocrine cell carcinoma is rare and associated with a poor prognosis. The first case was a man in his sixties with gastric endocrine cell carcinoma, of which a clinical finding was T2N1M0H1 (Stage IV). S-1 + CDDP therapy was selected and failed. CDDP+CPT-11 therapy was started and CT showed a partial response in ten months. But the tumor was re-grown and the patient died twenty months after diagnosis. The second case was a man in his seventies with gastric endocrine cell carcinoma, of which a clinical finding was T3N1M0H0P0, Stage IIIa, underwent total gastrectomy. Abdominal contrast-enhanced CT scan performed a month after the operation disclosed hepatic metastasis. After two months of S-1 regimen, CDDP + CPT-11 therapy was started.
authors.affiliation: Dept. of Surgery, Hokkaido P.W.F.A.C. Asahikawa-Kosei General Hospital.
authors.forename: Shiro
authors.initials: S
authors.lastname: Nakano
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shomura
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Akabane
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Inagaki
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Yanagida
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D004701:Endocrine Gland Neoplasms / Q000473:pathology* / Q000628:therapy; D006801:Humans; D000077146:Irinotecan; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000473:pathology* / Q000628:therapy; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin