title: [Report of two cases successfully treated by chemo-radiation against lymph node metastasis after gastric cancer surgery].
abstract: A 68-year-old male patient with mediastinal node metastasis 40 months after total gastrectomy for advanced gastric cancer, and a 72-year-old male patient with para aortic node metastasis were treated with concurrent chemo-radiotherapy of 1.8 Gy × 5 × 6 week with S-1 (100 mg/body, days 1-14 and 22-35) + docetaxel (30 mg/body, days 1, 8, 22, 29). Although two patients developed a lymph node recurrence during multiple chemotherapies including S-1, they have responded well and demonstrated complete response after chemo-radio therapy. Grade 3 esophagitis was sole adverse side effect. In contrast to the western countries, chemo-radio therapy was not recognized as a standard treatment for gastric cancer in Japan. However, our report suggested that chemo-radio therapy can be an option for the treatment of advanced gastric cancer.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Toshima Hospital.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Watayo
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Amagasa
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hataji
authors.forename: Norihito
authors.initials: N
authors.lastname: Kawasaki
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000628:therapy*; D043823:Taxoids; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid