title: Pleomorphic adenoma of the infratemporal fossa: case report and literature review.
abstract: OBJECTIVE
  To describe an unusual location for a common benign salivary gland neoplasm.
  
  
  METHODS
  Case report and literature review.
  
  
  METHODS
  We describe an unusual lesion found in the infratemporal fossa on computed tomography of the facial skeleton, including the clinical presentation, workup, and surgical approach. A complete PubMed search of atypical presentations of pleomorphic adenoma was performed. The literature was also reviewed for all neoplasms involving the infratemporal fossa, pterygomaxillary fissure, and pterygopalatine fossa.
  
  
  RESULTS
  Pleomorphic adenoma has been reported to arise in such diverse locations as the nasal septum, main stem bronchus, trachea, lacrimal gland and external auditory canal. One case has been reported to occur in pterygopalatine fossa. No cases of pleomorphic adenoma involving the infratemporal fossa have been reported. There are, however, a number of other neoplasms that can arise, or more frequently, directly invade, this region. Malignancies can often have an insidious presentation that is initially referred to other disease entities.
  
  
  CONCLUSIONS
  Though rare, there are a variety of neoplasms that can involve the infratemporal fossa. Patients with malignancies of this region usually present late in their disease course with invasion into surrounding structures. Diagnosis and approach to this region is difficult considering its concealed location.
authors.affiliation: Division of Otolaryngology - Head & Neck Surgery, Department of Surgery, Albany Medical Center, Albany, NY, USA. lowell.gurey@gmail.com
authors.forename: Lowell E
authors.initials: LE
authors.lastname: Gurey
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Brook
authors.forename: Steven M
authors.initials: SM
authors.lastname: Parnes
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D000328:Adult; D001265:Athletic Injuries / Q000150:complications*; D005151:Facial Injuries / Q000150:complications*; D006801:Humans; D008297:Male; D010027:Osteotomy; D012888:Skull Neoplasms / Q000473:pathology* / Q000601:surgery; D013701:Temporal Bone / Q000473:pathology*; D014057:Tomography, X-Ray Computed