title: [Orthotopic T pouch ileal neobladder: evaluations of urodynamics and upper urinary tract functions].
abstract: OBJECTIVE
  To evaluate the urodynamics and functions of upper urinary tract in a substitute of orthotopic T pouch ileal bladder.
  
  
  METHODS
  From June 2004 through September 2009, 90 patients underwent the construction of an orthotopic T pouch ileal neobladder after radical cystectomy for muscle-invasive bladder cancer. The radiographic or ultrasound evaluation of upper urinary tract, determination of renal functions and urodynamic evaluation of T pouch ileal neobladder were performed by data analysis.
  
  
  RESULTS
  Renal function as determined by serum creatinine remained in a normal range in all patients. Temporary dilation of renal pelvic and ureter was observed in 18 patients (20.0%) at Day 45 post-operation and then disappeared spontaneously in the late follow-up. A slight dilation of collecting system was found in other 4 patients (4.4%), but there was no negative impact on renal function. Reflux into afferent limb of neobladder was observed in 4 patients (4.4%) by cystography. Excellent daytime and nighttime continence was reported in 100% and 82.2% of evaluated patients respectively. The urodynamic assessment showed a mean capacity of (316 ± 96) ml with a mean intra-bladder pressure of (16 ± 10) cm H2O. These evaluated patients voided with a mean maximum intra-bladder pressure of (87 ± 25) cm H2O, a mean maximum flow rate of (17 ± 10) ml/s and a mean residual urine of (33 ± 29) ml.
  
  
  CONCLUSIONS
  With an intermediate follow-up, the functional results of T pouch ileal neobladder are encouraging with an excellent capacity and compliance, successful daytime and nighttime continence and anti-reflux mechanism.
authors.affiliation: Department of Urology, Capital Medical University, Beijing 100020, China.
authors.forename: Yi-nong
authors.initials: YN
authors.lastname: Niu
authors.forename: Nian-zeng
authors.initials: NZ
authors.lastname: Xing
authors.forename: Zheng-dong
authors.initials: ZD
authors.lastname: Zhou
authors.forename: Yu-dong
authors.initials: YD
authors.lastname: Chen
authors.forename: He
authors.initials: H
authors.lastname: Wang
authors.forename: Tong
authors.initials: T
authors.lastname: Zang
authors.forename: Jun-hui
authors.initials: JH
authors.lastname: Zhang
authors.forename: Jian-wen
authors.initials: JW
authors.lastname: Wang
authors.forename: Xi-quan
authors.initials: XQ
authors.lastname: Tian
authors.forename: Zhi-jin
authors.initials: ZJ
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D015653:Cystectomy / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D007082:Ileum / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000534:rehabilitation* / Q000601:surgery; D016476:Urinary Reservoirs, Continent; D014563:Urodynamics