title: Extraventricular anaplastic ependymoma with metastasis to scalp and neck.
abstract: We report a case of anaplastic ependymoma with extracranial metastases in a 22-year-old female. The patient originally presented with headaches and dysarthria. Neuroimaging revealed a large solid and cystic right fronto-temporal lesion. It was located completely extraventricularly and a glioblastoma was suspected based on the neuroimaging findings. A gross total resection was achieved. Histopathologic examination revealed an anaplastic ependymoma. The patient was treated with radiotherapy. Approximately 1 year after the initial surgery, the patient presented with metastatic disease to the scalp. At 2 years, an intraparotid metastasis was detected. Subsequent neck dissection revealed positive lymph nodes at several levels. It was followed by radiotherapy to the neck. 5 years after the initial surgery, the patient has residual metastatic disease. The case is discussed and the literature on extraventricular ependymal neoplasms is reviewed.
authors.affiliation: The Ruth and Bruce Rappaport Faculty of Medicine Technion - Israel Institute of Technology, 12 Efron St., Haifa, 31096, Israel.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Davis
authors.forename: Fauzia
authors.initials: F
authors.lastname: Hasan
authors.forename: Ilan
authors.initials: I
authors.lastname: Weinreb
authors.forename: M Christopher
authors.initials: MC
authors.lastname: Wallace
authors.forename: Tim-Rasmus
authors.initials: TR
authors.lastname: Kiehl
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology*; D004806:Ependymoma / Q000473:pathology*; D005260:Female; D006258:Head and Neck Neoplasms / Q000556:secondary*; D006801:Humans; D012535:Scalp / Q000473:pathology*; D055815:Young Adult