title: Cooperative catalytic reactions using organocatalysts and transition metal catalysts: enantioselective propargylic alkylation of propargylic esters with aldehydes.
abstract: The enantioselective propargylic alkylation of propargylic esters with aldehydes in the presence of a copper complex and an optically active secondary amine as cocatalysts has been found to give the corresponding propargylic alkylated products in good yields as a mixture of two diastereoisomers with a high enantioselectivity.
authors.affiliation: Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Yoshida
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ikeda
authors.forename: Gaku
authors.initials: G
authors.lastname: Hattori
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nishibayashi