title: Lymphoblastic lymphoma and leukemic blood profile in a red-tail boa (Boa constrictor constrictor) with concurrent inclusion body disease.
abstract: An adult male wild-caught true red-tail boa (Boa constrictor constrictor), imported from Surinam, was presented for anorexia, extreme lethargy, and coelomic swelling in the cranial third of the body, in the anatomic location of the thymus. The snake died a few minutes after blood sampling via cardiocentesis. Hematology revealed anemia and extreme leukocytosis (820 × 10(3)/ml) characterized by a predominance (95%) of lymphocytes. Necropsy revealed enlargement of most of the visceral organs. Histology confirmed lymphoblastic lymphoma with a leukemic blood profile and diffuse infiltration of some of the heart, thymus, bone marrow, kidney, spleen, lung, and liver. Several large intracytoplasmic eosinophilic inclusion bodies surrounded by narrow clear "halos" were identified within gastric mucosal cells, proximal and distal convoluted tubule epithelial cells, and splenic cells. The final diagnosis was lymphoblast lymphoma with a leukemic blood profile and concurrent inclusion body disease.
authors.affiliation: Clinique Vétérinaire du Village d'Auteuil, 35 rue Leconte de Lisle, 75016 Paris, France. Dr.L.Schilliger@clinvet-auteuil.com
authors.forename: Lionel
authors.initials: L
authors.lastname: Schilliger
authors.forename: Paolo
authors.initials: P
authors.lastname: Selleri
authors.forename: Fredric L
authors.initials: FL
authors.lastname: Frye
mesh_terms: D000818:Animals; D017821:Boidae / Q000097:blood*; D017809:Fatal Outcome; D002479:Inclusion Bodies / Q000473:pathology*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000473:pathology / Q000662:veterinary*