title: Late-life depression with comorbid cognitive impairment and disability: nonpharmacological interventions.
abstract: Less than half of older adults with depression achieve remission with antidepressant medications, and rates of remission are even poorer for those with comorbid conditions. Psychosocial interventions have been effective in treating geriatric depression, either alone or better yet, in combination with antidepressant medications. Traditional strategies for nonpharmacological treatment of late-life depression do not specifically address the co-occurring cognitive impairment and disability that is prevalent in this population. Newer therapies are recognizing the need to simultaneously direct treatment efforts in late-life depression towards the triad of depressive symptoms, cognitive dysfunction, and functional disability that is so often found in geriatric depression, and this comprehensive approach holds promise for improved treatment outcomes.
authors.affiliation: Department of Psychiatry, Weill Medical College of Cornell University, White Plains, NY, USA.
authors.forename: Victoria M
authors.initials: VM
authors.lastname: Wilkins
authors.forename: Dimitris
authors.initials: D
authors.lastname: Kiosses
authors.forename: Lisa D
authors.initials: LD
authors.lastname: Ravdin
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000928:Antidepressive Agents / Q000627:therapeutic use; D017028:Caregivers / Q000523:psychology; D003072:Cognition Disorders / Q000188:drug therapy / Q000453:epidemiology* / Q000628:therapy*; D015928:Cognitive Behavioral Therapy; D015897:Comorbidity; D003863:Depression / Q000188:drug therapy / Q000453:epidemiology* / Q000628:therapy*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents