title: An achiral manganese salen catalyst encapsulated in a peptidic phosphonate homochiral solid for the enantioselective formation of diols by consecutive epoxidation and hydration reactions.
abstract: An insoluble, porous, amorphous, homochiral material based on a polypeptide titanium-phosphonate scaffold with an encapsulated achiral Mn(III)-salen was prepared and characterized. Consecutive epoxidation and hydration of styrene and its derivatives by aqueous hypochlorite in THF showed the highly enantioselective (>99%) formation of styrene diol derivatives.
authors.affiliation: Department of Organic Chemistry, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Anat
authors.initials: A
authors.lastname: Milo
authors.forename: Ronny
authors.initials: R
authors.lastname: Neumann
mesh_terms: D000327:Adsorption; D002214:Capsules / Q000737:chemistry; D002384:Catalysis; D005029:Ethylenediamines / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry; D013237:Stereoisomerism; D020058:Styrene / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry; D014025:Titanium / Q000737:chemistry
chemical_list: D002214:Capsules; D005029:Ethylenediamines; D063065:Organophosphonates; D010455:Peptides; D013438:Sulfhydryl Compounds; D008345:Manganese; D020058:Styrene; C011452:disalicylaldehyde ethylenediamine; D014025:Titanium