title: Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
authors.forename: Einat
authors.initials: E
authors.lastname: Shacham-Shmueli
authors.forename: Alexander
authors.initials: A
authors.lastname: Beny
authors.forename: Ravit
authors.initials: R
authors.lastname: Geva
authors.forename: Arye
authors.initials: A
authors.lastname: Blachar
authors.forename: Arie
authors.initials: A
authors.lastname: Figer
authors.forename: Dan
authors.initials: D
authors.lastname: Aderka
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy* / Q000201:enzymology / Q000556:secondary; D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D001706:Biopsy; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D015254:DNA Modification Methylases / Q000032:analysis*; D045643:DNA Repair Enzymes / Q000032:analysis*; D003606:Dacarbazine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015536:Down-Regulation; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000201:enzymology / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D057285:Precision Medicine; D000077204:Temozolomide; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D025521:Tumor Suppressor Proteins / Q000032:analysis*
chemical_list: D018906:Antineoplastic Agents, Alkylating; D025521:Tumor Suppressor Proteins; D003606:Dacarbazine; D015254:DNA Modification Methylases; C515491:MGMT protein, human; D045643:DNA Repair Enzymes; D000077204:Temozolomide