title: [Genetic modification systems for Clostridium acetobutylicum].
abstract: Clostridium acetobutylicum, a biofuel-butanol producer, has attracted worldwide interests. Strain improvement is important for the process of biobutanol industrialization where efficient genetic modification systems are essential. In this review, the history of genetic modification systems of C. acetobutylicum was introduced, and the types and principles of these systems and their disadvantages are summarized and analysed. The development of updated genetic modification systems for C. acetobutylicum is also proposed.
authors.affiliation: Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
authors.forename: Hongjun
authors.initials: H
authors.lastname: Dong
authors.forename: Yanping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yin
authors.initials: Y
authors.lastname: Li
mesh_terms: D056804:Biofuels; D000440:Butanols / Q000032:analysis / Q000378:metabolism*; D046969:Clostridium acetobutylicum / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D005818:Genetic Engineering; D005821:Genetic Techniques
chemical_list: D056804:Biofuels; D000440:Butanols