title: Palladium-catalyzed conjugate addition to electron-deficient alkynes with benzenesulfinic acid derived from 1,2-bis(phenylsulfonyl)ethane: selective synthesis of (E)-vinyl sulfones.
abstract: A new, selective method for the synthesis of (E)-vinyl sulfones is presence by palladium-catalyzed C-S bond cleavage/conjugate addition. In the presence of Pd(OAc)(2) and DMEDA (N(1),N(2)-dimethylethane-1,2-diamine), 1,2-bis(phenylsulfonyl)ethane underwent the C-S bond cleavage, followed by conjugate addition to numerous electron-deficient alkynes afforded the corresponding (E)-vinyl sulfones in moderate to good yields.
authors.affiliation: Hunan Normal University, Changsha, China.
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Song
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Yan-Yun
authors.initials: YY
authors.lastname: Liu
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D005030:Ethylenes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013441:Sulfinic Acids / Q000737:chemistry*; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C558059:1,2-bis(phenylsulfonyl)ethane; D000480:Alkynes; D005030:Ethylenes; D013438:Sulfhydryl Compounds; D013441:Sulfinic Acids; D013450:Sulfones; C009873:divinyl sulfone; D010165:Palladium; C425152:benzenesulfinic acid