title: [Fatty liver and its clinical management in obese adolescents].
abstract: Liver steatosis, also called non-alcoholic fatty liver, is characterized by a pathological fat accumulation in the liver, leading to liver damage in the form of inflammation and fibrosis. These histological features are similar to those in alcoholic hepatitis. Obesity is known to be the most common cause of simple steatosis in the preadolescent and adolescent population with a consequent serious health risk. The aim of this study was to provide an update on the concepts, pathophysiology and clinical management of hepatic steatosis secondary to obesity at an early age.
authors.affiliation: Departamento de Enfermería, Facultad de Ciencias de la Salud, Universidad de Granada, Granada, España. emigoji@ugr.es
authors.forename: Emilio
authors.initials: E
authors.lastname: González Jiménez
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Schmidt Río-Valle
authors.forename: Judit
authors.initials: J
authors.lastname: Álvarez Ferre
mesh_terms: D052242:Adiponectin / Q000172:deficiency; D000293:Adolescent; D017209:Apoptosis; D015415:Biomarkers; D018925:Chemokines / Q000378:metabolism; D018450:Disease Progression; D005234:Fatty Liver / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005355:Fibrosis; D022781:Hepatocytes / Q000378:metabolism; D006801:Humans; D015228:Hypertriglyceridemia / Q000150:complications; D007333:Insulin Resistance; D007728:Kupffer Cells / Q000378:metabolism; D008103:Liver Cirrhosis / Q000209:etiology; D016031:Liver Transplantation; D008687:Metformin / Q000627:therapeutic use; D008954:Models, Biological; D065626:Non-alcoholic Fatty Liver Disease; D009765:Obesity / Q000150:complications*; D018384:Oxidative Stress; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D018925:Chemokines; D014810:Vitamin E; D014580:Ursodeoxycholic Acid; D008687:Metformin