title: Laser engineered multilayer coating of biphasic calcium phosphate/titanium nanocomposite on metal substrates.
abstract: In this work, laser coating of biphasic calcium phosphate/titanium (BCP/Ti) nanocomposite on Ti-6Al-4 V substrates was developed. A continuous wave neodymium-doped yttrium aluminium garnet (Nd:YAG) laser was used to form a robust multilayer of BCP/Ti nanocomposite starting from hydroxyapatite and titanium nanoparticles. In this process, low power coating is realized because of the strong laser-nanoparticle interaction and good sinterability of nanosized titanium. To guide the optimization of laser processing conditions for the coating process, a multiphysics model coupling electromagnetic module with heat transfer module was developed. This model was validated by laser coating experiments. Important features of the coated samples, including microstructures, chemical compositions, and interfacial bonding strength, were characterized. We found that a multilayer of BCP, consisting of 72% hydroxyapatite (HA) and 28% beta-tricalcium phosphate (β-TCP), and titanium nanocomposite was formed on Ti-6Al-4 V substrates. Significantly, the coating/substrate interfacial bonding strength was found to be two times higher than that of the commercial plasma sprayed coatings. Preliminary cell culture studies showed that the resultant BCP/Ti nanocomposite coating supported the adhesion and proliferation of osteoblast-like UMR-106 cells.
authors.affiliation: School of Industrial Engineering, Purdue University , West Lafayette, Indiana 47906, USA.
authors.forename: Martin Yi
authors.initials: MY
authors.lastname: Zhang
authors.forename: Chang
authors.initials: C
authors.lastname: Ye
authors.forename: Uriel Joseph
authors.initials: UJ
authors.lastname: Erasquin
authors.forename: Toan
authors.initials: T
authors.lastname: Huynh
authors.forename: Chengzhi
authors.initials: C
authors.lastname: Cai
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Cheng
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002130:Calcium Phosphates / Q000737:chemistry* / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects; D018929:Cell Culture Techniques; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D017886:Durapatite / Q000737:chemistry; D007834:Lasers; D008422:Materials Testing; D053761:Nanocomposites / Q000737:chemistry*; D051381:Rats; D015203:Reproducibility of Results; D013499:Surface Properties; D013696:Temperature; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D017886:Durapatite; C020243:calcium phosphate; D014025:Titanium