title: Molecular characterization of rotavirus diarrhea among children in South Korea: detection of an unusual G11 strain.
abstract: Among 312 rotavirus-positive samples collected from eight hospitals across South Korea during 2008 and 2009, the most prevalent circulating G genotype was G1 (35.9%), followed by G3 (24.7%), G2 (17.0%), G4 (7.7%), and G9 (2.6%). Notably, one unusual G11 lineage III strain-the first hypoendemic infection case in the world-was found. Of the P genotypes, P[8] (43.9%) was the most common, followed by P[6] (29.5%), P[4] (9.3%) and P[9] (0.6%). Determining G- and P-type combinations showed that G1P[8] was the most prevalent (20.5%), followed by G2P[6] (12.8%) and G3P[8] (12.8%). These findings provide new information concerning the current prevalence and spread of the rare G11 rotavirus.
authors.affiliation: Department of Pediatrics, Kangwon National University School of Medicine, Chuncheon, Korea.
authors.forename: Jung Ok
authors.initials: JO
authors.lastname: Shim
authors.forename: In Hyuk
authors.initials: IH
authors.lastname: Baek
authors.forename: Van Phan
authors.initials: VP
authors.lastname: Le
authors.forename: Eun-Mi
authors.initials: EM
authors.lastname: Ko
authors.forename: Won-Seok
authors.initials: WS
authors.lastname: Seok
authors.forename: Young
authors.initials: Y
authors.lastname: Uh
authors.forename: Ja Kyoung
authors.initials: JK
authors.lastname: Kim
authors.forename: Sung Yeon
authors.initials: SY
authors.lastname: Ahn
authors.forename: Hyeon Soo
authors.initials: HS
authors.lastname: Lee
authors.forename: Eell
authors.initials: E
authors.lastname: Ryoo
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Shim
authors.forename: Wonkeun
authors.initials: W
authors.lastname: Song
authors.forename: Inseok
authors.initials: I
authors.lastname: Lim
authors.forename: Wonyong
authors.initials: W
authors.lastname: Kim
mesh_terms: D002675:Child, Preschool; D016000:Cluster Analysis; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D056910:Republic of Korea / Q000453:epidemiology; D012401:Rotavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology*; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral