title: Correlational analysis and predictive validity of psychological constructs related with pain in fibromyalgia.
abstract: BACKGROUND
  Fibromyalgia (FM) is a prevalent and disabling disorder characterized by a history of widespread pain for at least three months. Pain is considered a complex experience in which affective and cognitive aspects are crucial for prognosis. The aim of this study is to assess the importance of pain-related psychological constructs on function and pain in patients with FM.
  
  
  METHODS
  
  
  
  METHODS
  Multicentric, naturalistic, one-year follow-up study. SETTING AND STUDY SAMPLE: Patients will be recruited from primary care health centres in the region of Aragon, Spain. Patients considered for inclusion are those aged 18-65 years, able to understand Spanish, who fulfil criteria for primary FM according to the American College of Rheumatology, with no previous psychological treatment.
  
  
  METHODS
  The variables measured will be the following: main variables (pain assessed with a visual analogue scale and with sphygmomanometer and general function assessed with Fibromyalgia Impact Questionnaire, and), psychological constructs (pain catastrophizing, pain acceptance, mental defeat, psychological inflexibility, perceived injustice, mindfulness, and positive and negative affect), and secondary variables (sociodemographic variables, anxiety and depression assessed with Hospital Anxiety and Depression Scale, and psychiatric interview assessed with MINI). Assessments will be carried at baseline and at one-year follow-up.
  
  
  RESULTS
  Pain Visual Analogue Scale.
  
  
  METHODS
  The existence of differences in socio-demographic, main outcome and other variables regarding pain-related psychological constructs will be analysed using Chi Square test for qualitative variables, or Student t test or variance analysis, respectively, for variables fulfilling the normality hypothesis. To assess the predictive value of pain-related psychological construct on main outcome variables at one-year follow-up, use will be made of a logistic regression analysis adjusted for socio-demographic and clinical variables. A Spearman Rho non-parametric correlation matrix will be developed to determine possible overlapping between pain-related psychological constructs.
  
  
  CONCLUSIONS
  In recent years, the relevance of cognitive and affective aspects for the treatment of chronic pain, not only in FM but also in other chronic pain diseases, has been widely acknowledged. However, the relative importance of these psychological constructs, the relationship and possible overlapping between them, or the exact meaning of them in pain are not enough known.
authors.affiliation: Servicio de Psiquiatría, Hospital Miguel Servet y Universidad de Zaragoza, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Maurel
authors.forename: Baltasar
authors.initials: B
authors.lastname: Rodero
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Lopez-del-Hoyo
authors.forename: Juan V
authors.initials: JV
authors.lastname: Luciano
authors.forename: Eva
authors.initials: E
authors.lastname: Andrés
authors.forename: Miquel
authors.initials: M
authors.lastname: Roca
authors.forename: Raquel del Moral
authors.initials: Rdel M
authors.lastname: Bergos
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Ruiz-Lancina
authors.forename: Javier
authors.initials: J
authors.lastname: García-Campayo
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005356:Fibromyalgia / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000175:diagnosis / Q000209:etiology / Q000523:psychology*; D009483:Neuropsychological Tests; D010146:Pain / Q000150:complications / Q000175:diagnosis / Q000523:psychology*; D010147:Pain Measurement / Q000379:methods; D011237:Predictive Value of Tests; D011788:Quality of Life / Q000523:psychology; D015203:Reproducibility of Results; D055815:Young Adult