title: A systematic review of randomised controlled trials of the effects of warmed irrigation fluid on core body temperature during endoscopic surgeries.
abstract: OBJECTIVE
  The purpose of this systematic review was to establish whether warmed irrigation fluid temperature could decrease the drop of body temperature and incidence of shivering and hypothermia.
  
  
  BACKGROUND
  Irrigation fluid, which is used in large quantities during endoscopic surgeries at room temperature, is considered to be associated with hypothermia and shivering. It remains controversial whether using warmed irrigation fluid to replace room-temperature irrigation fluid will decrease the drop of core body temperature and the occurrence of hypothermia.
  
  
  METHODS
  A comprehensive search (computerised database searches, footnote chasing, citation chasing) was undertaken to identify all the randomised controlled trials that explored temperature of irrigation fluid in endoscopic surgery. An approach involving meta-analysis was used.
  
  
  METHODS
  We searched PubMed, EMBASE, Cochrane Library, SCI, China academic journals full-text databases, Chinese Biomedical Literature Database, Chinese scientific journals databases and Chinese Medical Association Journals for trials that meet the inclusion criteria. Study quality was assessed using standards recommended by Cochrane Library Handbook 5.0.1. Disagreement was resolved by consensus.
  
  
  RESULTS
  Thirteen randomised controlled trials including 686 patients were identified. The results showed that room-temperature irrigation fluid caused a greater drop of core body temperature in patients, compared to warmed irrigation fluid (p < 0.00001; I(2) = 85%). The occurrence of shivering [odds ratio (OR) 5.13, 95% CI: 2.95-10.19, p < 0.00001; I(2) = 0%] and hypothermia (OR 22.01, 95% CI: 2.03-197.08, p = 0.01; I(2) = 64%) in the groups having warmed irrigation fluid were lower than the group of studies having room-temperature fluid.
  
  
  CONCLUSIONS
  In endoscopic surgeries, irrigation fluid is recommended to be warmed to decrease the drop of core body temperature and the risk of perioperative shivering and hypothermia.
  
  
  CONCLUSIONS
  Warming irrigating fluid should be considered standard practice in all endoscopic surgeries.
authors.affiliation: Lanzhou and Nursing Department, The Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University,Tianjin Medical University, Tianjin, China.
authors.forename: Yinghui
authors.initials: Y
authors.lastname: Jin
authors.forename: Jinhui
authors.initials: J
authors.lastname: Tian
authors.forename: Mei
authors.initials: M
authors.lastname: Sun
authors.forename: Kehu
authors.initials: K
authors.lastname: Yang
mesh_terms: D001831:Body Temperature; D004724:Endoscopy; D006801:Humans; D007035:Hypothermia / Q000209:etiology* / Q000517:prevention & control*; D016032:Randomized Controlled Trials as Topic; D012768:Shivering; D013696:Temperature; D007507:Therapeutic Irrigation / Q000379:methods*