title: [Epidemiological investigation on major depressive disorder in the most heavily damaged areas from Wenchuan earthquake in 2008].
abstract: OBJECTIVE
  To assess the prevalence, demographic characteristics, risk factors and protective factors on major depression disorder (MDD) among the affected people in the epicenter, 7 months after the 2008-earthquake in Wenchuan, China.
  
  
  METHODS
  Stratified multistage cluster randomization was conducted to choose 14 503 subjects aged 15 years or over in the city of Dujiangyan, Beichuan county and Qingchuan county, Sichuan province. We used the general health questionnaire (GHQ-12) as the screening instrument, and the structured clinical interview for DSM-IV-TR axis I disorder-patient edition (SCID-I/P) as the tool for diagnosis.
  
  
  RESULTS
  There were 180 persons diagnosed as MDD with other 13 asymptomatic ones. The point prevalence of MDD was 1.27% and the lifetime prevalence was 1.36%. Risk factors were including:being female (OR = 1.56, 95%CI: 1.136 ∼ 2.143, P < 0.05), co-morbidity with somatic diseases (OR = 4.02, 95%CI: 2.75 - 5.90, P < 0.05), wounded in the earthquake (OR = 3.29, 95%CI: 1.92 - 5.65, P < 0.05), property loss up to 10 000 - 20 000 Yuan (OR = 2.09, 95%CI: 1.18 - 3.69, P < 0.05), property loss up to > 20 000 Yuan (OR = 2.54, 95% CI: 1.38 - 4.68, P < 0.05), death or missing of family members (OR = 3.79, 95%CI: 2.08 - 6.89, P < 0.05) and in middle-age (OR = 2.31, 95%CI: 1.38 - 3.86, P < 0.05) etc. Having had a job seemed to be a protective factor (OR = 0.60, 95%CI: 0.43 - 0.83, P < 0.05).
  
  
  CONCLUSIONS
  Major depressive disorder appeared to be a common psychiatric disease in these quake-stricken areas, that causing serious problems. Sustained follow-up and care provided to the affected people in these areas were of extreme importance.
authors.affiliation: Department of Psychiatry, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Ming-jin
authors.initials: MJ
authors.lastname: Huang
authors.forename: Lan-ting
authors.initials: LT
authors.lastname: Guo
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Xue-li
authors.initials: XL
authors.lastname: Sun
authors.forename: Bing-zhi
authors.initials: BZ
authors.lastname: Zhang
authors.forename: Quan-min
authors.initials: QM
authors.lastname: Yi
authors.forename: Ya-ming
authors.initials: YM
authors.lastname: Chen
authors.forename: Qiang
authors.initials: Q
authors.lastname: Cao
authors.forename: Jin
authors.initials: J
authors.lastname: Peng
authors.forename: Ling
authors.initials: L
authors.lastname: Wei
authors.forename: Xia-fei
authors.initials: XF
authors.lastname: Huang
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Yin
authors.forename: Gui-fen
authors.initials: GF
authors.lastname: Xiong
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.forename: Yu-lian
authors.initials: YL
authors.lastname: Liao
authors.forename: Xiao-ling
authors.initials: XL
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Yuan-qi
authors.initials: YQ
authors.lastname: Xiao
authors.forename: Shan
authors.initials: S
authors.lastname: Jiang
authors.forename: Jing
authors.initials: J
authors.lastname: Ye
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D003865:Major Depressive Disorder / Q000453:epidemiology*; D004190:Disasters; D055866:Earthquakes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013313:Stress Disorders, Post-Traumatic / Q000453:epidemiology*; D055815:Young Adult