title: [Response and remission in schizophrenic subjects].
abstract: BACKGROUND
  This naturalistic study investigates in detail symptom reduction during acute inpatient treatment (response), long-term symptom improvement in the post-acute phase (remission) and the rate of re-hospitalisations.
  
  
  METHODS
  A total of 183 patients were enrolled. Criteria for response were PANSS total score and syndrome reductions of 20, 30, 40 and 50%. Remission criteria employed were based on recommendations from Andreasen et al.
  
  
  RESULTS
  The average length of stay was 45.6 days (SD 42.7). PANSS total score response rates were found to be 63.9% for the 20% level and were reduced in the following consecutive levels by approximately 15%. Only 10.3% of the patients remitted during a 1-year follow-up period. At least one re-hospitalisation was reported for 43.9% of the subjects.
  
  
  CONCLUSIONS
  Compared to previous randomised and controlled trials, the rates of response and remission are significantly lower. In daily inpatient care, the chronic course of schizophrenia is far commoner than expected from previous reports.
authors.affiliation: Karl-Jaspers-Klinik, Psychiatrieverbund Oldenburger Land gGmbH, Bad Zwischenahn, Deutschland. joerg.zimmermann@karl-jaspers-klinik.de
authors.forename: J
authors.initials: J
authors.lastname: Zimmermann
authors.forename: A
authors.initials: A
authors.lastname: Wolter
authors.forename: N R
authors.initials: NR
authors.lastname: Krischke
authors.forename: U W
authors.initials: UW
authors.lastname: Preuss
authors.forename: T
authors.initials: T
authors.lastname: Wobrock
authors.forename: P
authors.initials: P
authors.lastname: Falkai
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005858:Germany / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012074:Remission Induction; D018570:Risk Assessment; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult