title: Determination of the depth dose distribution of proton beam using PRESAGE™ dosimeter.
abstract: PRESAGE™ dosimeter dosimeter has been proved useful for 3D dosimetry in conventional photon therapy and IMRT [1-5]. Our objective is to examine the use of PRESAGE™ dosimeter for verification of depth dose distribution in proton beam therapy. Three PRESAGE™ samples were irradiated with a 79 MeV un-modulated proton beam. Percent depth dose profile measured from the PRESAGE™ dosimeter is compared with data obtained in a water phantom using a parallel plate Advanced Markus chamber. The Bragg-peak position determined from the PRESAGE™ is within 2 mm compared to measurements in water. PRESAGE™ shows a highly linear response to proton dose. However, PRESAGE™ also reveals an underdosage around the Bragg peak position due to LET effects. Depth scaling factor and quenching correction factor need further investigation. Our initial result shows that PRESAGE™ has promising dosimetric characteristics that could be suitable for proton beam dosimetry.
authors.affiliation: Midwest Proton Radiotherapy Institute, Bloomington, IN, USA 47404.
authors.forename: L
authors.initials: L
authors.lastname: Zhao
authors.forename: I J
authors.initials: IJ
authors.lastname: Das
authors.forename: Q
authors.initials: Q
authors.lastname: Zhao
authors.forename: A
authors.initials: A
authors.lastname: Thomas
authors.forename: J
authors.initials: J
authors.lastname: Adamovics
authors.forename: M
authors.initials: M
authors.lastname: Oldman