title: [A case of unresectable advanced gastric cancer successfully treated with chemotherapy after gastrojejunostomy].
abstract: We report a patient with unresectable advanced gastric cancer who was successfully treated with chemotherapy after gastrojejunostomy. A 64-year-old man was admitted to our hospital complaining of appetite loss and body weight loss. Abdominal enhanced CT revealed a gastric wall thickening and swelling of lymph nodes in the lesser curvature. Upper gastrointestinal endoscopy showed a gastric cancer in the antrum of the stomach. He underwent laparotomy, which revealed a T4 tumor invading the pancreas. Gastrojejunostomy was performed. After the operation, intake therapy of 80-100 mg S-1 was started for four weeks followed by two weeks rest as one course. After 2 courses of the therapy, abdominal enhanced CT showed a partial response of the lymph nodes. He is alive for 19 months after the operation. Abdominal enhanced CT showed a stable disease. This case suggested that S-1 chemotherapy after gastrojejunostomy was effective for unresectable advanced gastric cancer because of the long-term survival and an improvement of the patient's quality of life.
authors.affiliation: Dept. of Digestive Surgery and Surgical Oncology, Yamaguchi University Graduate School of Medicine.
authors.forename: Yoshitaro
authors.initials: Y
authors.lastname: Shindo
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Yoshino
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Maeda
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Suzuki
authors.forename: Masaaki
authors.initials: M
authors.lastname: Oka
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy*; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004338:Drug Combinations; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000628:therapy*; D005641:Tegafur / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid