title: Diastereoselective hydroformylation of 2,5-cyclohexadienyl-1-carbinols with catalytic amounts of a reversibly bound directing group.
abstract: A phosphinite plays a role as a reversibly bound directing group for the regio- and diastereoselective hydroformylation of 2,5-cyclohexadienyl-1-carbinols. Of the two alkene functions only one was functionalized through hydroformylation to form a synthetically attractive quaternary carbon center leaving the second alkene function for potential further functionalization.
authors.affiliation: Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104 Freiburg i. Bg., Germany.
authors.forename: Ippei
authors.initials: I
authors.lastname: Usui
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nomura
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit