title: [A case of liver metastasis from gastric cancer treated with stereotactic radiation therapy].
abstract: We report a case of liver metastasis from gastric cancer that was effectively controlled with stereotactic radiation therapy (SRT). A 77-year-old man underwent total gastrectomy, splenectomy, cholecystectomy and D2 dissection in February 2007 for type 3 gastric cancer in the upper third area that was diagnosed well to moderately differentiated adenocarcinoma and Stage II (T3 (SE) N0 H0 P0 CY0 M0). He suffered from the liver and peritoneal metastases with ascites in December 2007, so S-1 was administered. Ascites was disappeared, but liver metastasis was enlarged. Therefore, SRT (total of 52.8 Gy per 4 fractions) was performed for the liver metastasis. A clear reduction in tumor size was noted and he was presently alive with no sign of recurrence after 2 years. Immediately after SRT, grade 3 neutropenia and grade 2 AST/ALT elevation were occurred. Grade 2 pneumothorax and pleural effusion were recognized in August 2009 as tardive adverse event. It is thought that SRT is one of effective treatments for liver metastasis from gastric cancer.
authors.affiliation: Dept. of Surgery, NTT West Osaka Hospital.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kimura
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yano
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyazaki
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Nakamura
authors.forename: Katsuki
authors.initials: K
authors.lastname: Danno
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kanoh
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tono
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakano
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Kagawa
authors.forename: Takushi
authors.initials: T
authors.lastname: Monden
authors.forename: Shingi
authors.initials: S
authors.lastname: Imaoka
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy*; D000368:Aged; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D008297:Male; D010534:Peritoneal Neoplasms / Q000556:secondary; D016634:Radiosurgery; D013274:Stomach Neoplasms / Q000473:pathology*