title: Preparation, spectroscopy, EXAFS, electrochemistry and pharmacology of new ruthenium(II) carbonyl complexes containing ferrocenylthiosemicarbazone and triphenylphosphine/arsine.
abstract: A new series of new hetero-bimetallic complexes containing iron and ruthenium of the general formula [RuCl(CO)(B)(EPh3)(L)] (where E=P or As; B=PPh3, AsPh3, py or pip; L=ferrocene derived monobasic bidentate thiosemicarbazone ligand) have been synthesized by the reaction between ferrocene-derived thiosemicarbazones and ruthenium(II) complexes of the type [RuHCl(CO)(B)(EPh3)2] (where E=P or As; B=PPh3, AsPh3, py or pip). The new complexes have been characterized by elemental analyses, IR, electronic, NMR (1H, 13C and 31P), EXAFS (extended X-ray absorption fine structure spectroscopy) and cyclic voltammetric techniques. Antibacterial activity of the new complexes has been screened against Escherichia coli, Vibrio cholerae, and Pseudomonas aeruginosa species.
authors.affiliation: Department of Chemistry, Bharathiar University, Coimbatore 641 046, India.
authors.forename: R
authors.initials: R
authors.lastname: Prabhakaran
authors.forename: S
authors.initials: S
authors.lastname: Anantharaman
authors.forename: M
authors.initials: M
authors.lastname: Thilagavathi
authors.forename: M V
authors.initials: MV
authors.lastname: Kaveri
authors.forename: P
authors.initials: P
authors.lastname: Kalaivani
authors.forename: R
authors.initials: R
authors.lastname: Karvembu
authors.forename: N
authors.initials: N
authors.lastname: Dharmaraj
authors.forename: H
authors.initials: H
authors.lastname: Bertagnolli
authors.forename: F
authors.initials: F
authors.lastname: Dallemer
authors.forename: K
authors.initials: K
authors.lastname: Natarajan
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001152:Arsenicals / Q000737:chemistry / Q000494:pharmacology*; D055664:Electrochemical Techniques / Q000379:methods*; D004926:Escherichia coli / Q000187:drug effects; D005296:Ferrous Compounds / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009943:Organophosphorus Compounds / Q000737:chemistry / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012428:Ruthenium / Q000494:pharmacology*; D012545:Schiff Bases; D017550:Spectroscopy, Fourier Transform Infrared; D013882:Thiosemicarbazones / Q000737:chemistry / Q000494:pharmacology*; D014734:Vibrio cholerae / Q000187:drug effects; D056928:X-Ray Absorption Spectroscopy
chemical_list: D000900:Anti-Bacterial Agents; D001152:Arsenicals; D005296:Ferrous Compounds; D008024:Ligands; D009943:Organophosphorus Compounds; D012545:Schiff Bases; D013882:Thiosemicarbazones; C061896:triphenylphosphine; D012428:Ruthenium; C006633:arsine