title: Benefits from treatment and control of patients with resistant hypertension.
abstract: Resistant hypertension is commonly found in everyday clinical practice. However, the risks of resistant hypertension, as well as the benefits of treatment and control of blood pressure in patients with resistant hypertension remain vaguely clarified. Data from small clinical studies and observational cohorts suggest that patients with resistant hypertension are at increased cardiovascular risk, while control of blood pressure offers substantial benefits. It has to be noted however that data from appropriate large randomized studies are missing, and resistant hypertension remains remarkably understudied. Resistant hypertension has attracted significant scientific interest lately, as new therapeutic modalities become available. The interventional management of resistant hypertension either by carotid baroreceptor stimulation or renal sympathetic denervation is currently under investigation with promising preliminary results. This review presents available evidence regarding the benefits of treatment and control of blood pressure in patients with resistant hypertension and offers a critical evaluation of existing data in this field.
authors.affiliation: Veterans Affairs Medical Center, George Washington University, Washington, DC 20422, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Doumas
authors.forename: Vasilios
authors.initials: V
authors.lastname: Papademetriou
authors.forename: Stella
authors.initials: S
authors.lastname: Douma
authors.forename: Charles
authors.initials: C
authors.lastname: Faselis
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Tsioufis
authors.forename: Eugene
authors.initials: E
authors.lastname: Gkaliagkousi
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Petidis
authors.forename: Chrysanthos
authors.initials: C
authors.lastname: Zamboulis