title: [Quantitative evaluation on the effectiveness of prevention and control measures against pandemic influenza A (H1N1) in Beijing, 2009].
abstract: OBJECTIVE
  To quantitatively evaluate the effectiveness of prevention and control measures against pandemic influenza A (H1N1) in Beijing, 2009 and to provide evidence for developing and adjusting strategies for prevention and control of the disease.
  
  
  METHODS
  Considering the seasonality and the number of vaccination on pandemic influenza A (H1N1), data regarding pandemic influenza A (H1N1) in Beijing were collected and analyzed. Based on the dynamics of infectious disease transmission, a quantitative model for evaluation of prevention and control measures was developed.
  
  
  RESULTS
  Both latency and infectious periods of pandemic influenza A (H1N1) were estimated to be 1.82 days and 2.08 days, respectively. The effective reproduction numbers of the three periods were 1.13, 1.65 and 0.96, respectively. Thanks to the implementation of a series of measures to prevent and control pandemic influenza A (H1N1), the cumulative number of laboratory-confirmed cases of pandemic influenza A (H1N1) was reduced, making it much smaller than what would have been under the natural situation. Specifically, the program on pandemic (H1N1) 2009 vaccination reduced the cumulative number of laboratory-confirmed cases by 24.08% and postponed the peak time.
  
  
  CONCLUSIONS
  Measures that had been taken during this period, had greatly contributed to the successful prevention and control of pandemic influenza A (H1N1). The 2009 Pandemic (H1N1) vaccination was confirmed to have contributed to the decrease of cumulative number of laboratory-confirmed cases and postponed the peak arrival time.
authors.affiliation: Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Wang
authors.forename: Peng
authors.initials: P
authors.lastname: Yang
authors.forename: Zhi-dong
authors.initials: ZD
authors.lastname: Cao
authors.forename: Da-jun
authors.initials: DJ
authors.lastname: Zeng
authors.forename: Jiang
authors.initials: J
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Zahng
authors.forename: Hai-kun
authors.initials: HK
authors.lastname: Qian
authors.forename: Xiao-min
authors.initials: XM
authors.lastname: Peng
authors.forename: Hui-jie
authors.initials: HJ
authors.lastname: Liang
authors.forename: Xing-huo
authors.initials: XH
authors.lastname: Pang
authors.forename: Ying
authors.initials: Y
authors.lastname: Deng
authors.forename: Xiong
authors.initials: X
authors.lastname: He
authors.forename: Quan-yi
authors.initials: QY
authors.lastname: Wang
mesh_terms: D002681:China / Q000453:epidemiology; D005069:Evaluation Studies as Topic; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D008962:Models, Theoretical; D058873:Pandemics