title: Stem cells--prospects in dentistry.
abstract: Stem cell biology, an emerging field of research, provides promising methods in vitro as well as in vivo in animal models which make speculation about a future application in human dentistry reasonable. The objective of this study was to review the literature of stem cell research concerning fields relevant for dentistry. In dentistry, different stem cells are discussed. Adult dental ectomesenchymal stem cells seem promising for future therapy. Human stem cells have been isolated from the dental pulp, exfoliated deciduous teeth, the periodontal ligament, the dental follicle and the dental papilla. Stem cell markers such as STRO-1 were used for the characterization and isolation of stem cells. Adult dental stem cells can differentiate into many dental components, such as dentin, periodontal ligament, cement and dental pulp tissue, but not into enamel.
authors.affiliation: Clinic for Dental Prosthodontics and Biomedical Materials Science, Center for Dentistry and Oral Medicine, Medical University of Hannover, Germany. ulmer.franziska@mh-hannover.de
authors.forename: Franziska L
authors.initials: FL
authors.lastname: Ulmer
authors.forename: Andreas
authors.initials: A
authors.lastname: Winkel
authors.forename: Philipp
authors.initials: P
authors.lastname: Kohorst
authors.forename: Meike
authors.initials: M
authors.lastname: Stiesch
mesh_terms: D053687:Adult Stem Cells; D000818:Animals; D000943:Antigens, Differentiation; D015415:Biomarkers; D003771:Dental Papilla / Q000166:cytology; D003782:Dental Pulp / Q000166:cytology*; D003795:Dental Sac / Q000166:cytology; D004847:Epithelial Cells; D006801:Humans; D059630:Mesenchymal Stem Cells; D009805:Odontogenesis; D010513:Periodontal Ligament / Q000166:cytology; D012038:Regeneration; D014094:Tooth, Deciduous / Q000166:cytology*
chemical_list: D000943:Antigens, Differentiation; D015415:Biomarkers