title: Field efficacy of new larvicide products for control of multi-resistant Aedes aegypti populations in Martinique (French West Indies).
abstract: World-wide dengue vector control is hampered by the spread of insecticide resistance in Aedes aegypti. We report the resistance status of a wild Ae. aegypti population from Martinique (Vauclin) to conventional larvicides (Bacillus thuringiensis var israeliensis [Bti] and temephos) and potential alternatives (spinosad, diflubenzuron, and pyriproxyfen). The efficacy and residual activity of these insecticides were evaluated under simulated and field conditions. The Vauclin strain exhibited a high level of resistance to temephos, a tolerance to insect growth regulators, and full susceptibility to spinosad and Bti. In simulated trials, pyriproxyfen and Bti showed long residual activities in permanent breeding containers (28 and 37 weeks), whereas under field conditions they failed to curtail Ae. aegypti populations after four weeks. Conversely, diflubenzuron and spinosad showed a residual efficacy of 16 weeks, suggesting that these chemicals may be promising alternatives to Bti and temephos for controlling insecticide-resistant Ae. aegypti populations.
authors.affiliation: Laboratoire de Lutte Contre les Insectes Nuisibles, Institut de Recherche pour le Développement, Montpellier, France. sebastien.marcombe@ird.fr
authors.forename: Sébastien
authors.initials: S
authors.lastname: Marcombe
authors.forename: Frédéric
authors.initials: F
authors.lastname: Darriet
authors.forename: Philip
authors.initials: P
authors.lastname: Agnew
authors.forename: Manuel
authors.initials: M
authors.lastname: Etienne
authors.forename: Marie-Michelle
authors.initials: MM
authors.lastname: Yp-Tcha
authors.forename: André
authors.initials: A
authors.lastname: Yébakima
authors.forename: Vincent
authors.initials: V
authors.lastname: Corbel
mesh_terms: D000330:Aedes; D000818:Animals; D001681:Biological Assay; D003715:Dengue / Q000517:prevention & control / Q000635:transmission; D004305:Dose-Response Relationship, Drug; D007303:Insect Vectors; D007305:Insecticide Resistance; D007306:Insecticides / Q000592:standards*; D007814:Larva; D008395:Martinique; D009032:Mosquito Control / Q000379:methods*
chemical_list: D007306:Insecticides