title: Can "dor to dor+rec neurorrhaphy" by biodegradable chitin conduit be a new method for peripheral nerve injury?
abstract: This study aims to estimate the effects of using one donor nerve to repair the injured nerve and itself simultaneously by biodegradable chitin conduit. Proximal median nerve served as donor nerve to repair the distal median and whole ulnar nerve. Four months postoperation, the number of myelinated axons and nerve conduction velocities of the distal median and ulnar nerve were (2085 ± 215 and 24.4 ± 5.9 m/s), and (1193 ± 102 and 30.7 ± 11.2 m/s). Recovery of the tetanic muscle forces of the reinvervated muscles were also observed. It suggests that Dor to Dor+Rec neurorrhaphy is a practical method for severe peripheral nerve injury.
authors.affiliation: Department of Orthopedics and Trauma, Peking University People's Hospital, South Xi-Zhi-Men Street #11, Beijing, China.
authors.forename: Xiao Feng
authors.initials: XF
authors.lastname: Yin
authors.forename: Yu Hui
authors.initials: YH
authors.lastname: Kou
authors.forename: Yan Hua
authors.initials: YH
authors.lastname: Wang
authors.forename: Peixun
authors.initials: P
authors.lastname: Zhang
authors.forename: Dian Yin
authors.initials: DY
authors.lastname: Zhang
authors.forename: Zhong Guo
authors.initials: ZG
authors.lastname: Fu
authors.forename: Hong Bo
authors.initials: HB
authors.lastname: Zhang
authors.forename: Bao Guo
authors.initials: BG
authors.lastname: Jiang
mesh_terms: D020341:Absorbable Implants; D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001369:Axons / Q000502:physiology; D002686:Chitin / Q000627:therapeutic use*; D055724:Electrophysiological Phenomena; D008297:Male; D008475:Median Nerve / Q000601:surgery; D008866:Microsurgery / Q000379:methods; D009416:Nerve Regeneration / Q000502:physiology*; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000601:surgery*; D011817:Rabbits; D019651:Plastic Surgery Procedures / Q000379:methods; D014459:Ulnar Nerve / Q000601:surgery
chemical_list: D002686:Chitin