title: Rocuronium antagonized by sugammadex for series of electroconvulsive therapy (ECT) in a patient with pseudocholinesterase deficiency.
abstract: We report the anesthetic management of a patient with catatonic schizophrenia and pseudocholinesterase deficiency, using the nondepolarizing neuromuscular blocking drug, rocuronium, reversed by its specific reversal agent, sugammadex, for a series of electroconvulsive therapy sessions. Rocuronium and sugammadex were used every 48 hours for 8 consecutive times and proved to be an effective and safe combination in a situation where succinylcholine was contraindicated.
authors.affiliation: Second Department of Anaesthesiology, School of Medicine, University of Athens, Attikon Hospital, Athens, Greece. chrysabatistaki@yahoo.gr
authors.forename: Chrysanthi
authors.initials: C
authors.lastname: Batistaki
authors.forename: Kyriakos
authors.initials: K
authors.lastname: Kesidis
authors.forename: Stylliani
authors.initials: S
authors.lastname: Apostolaki
authors.forename: Georgia
authors.initials: G
authors.lastname: Kostopanagiotou
mesh_terms: D000328:Adult; D000732:Androstanols / Q000037:antagonists & inhibitors*; D001049:Apnea; D002091:Butyrylcholinesterase / Q000172:deficiency; D002802:Cholinesterases / Q000172:deficiency; D004342:Drug Hypersensitivity / Q000150:complications; D004347:Drug Interactions; D004565:Electroconvulsive Therapy; D006801:Humans; D008297:Male; D008661:Metabolism, Inborn Errors; D003473:Neuromuscular Nondepolarizing Agents / Q000037:antagonists & inhibitors; D000077123:Rocuronium; D012560:Schizophrenia, Catatonic / Q000150:complications* / Q000628:therapy*; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000627:therapeutic use
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D002091:Butyrylcholinesterase; D002802:Cholinesterases; D000077123:Rocuronium