title: [A case of Vp4 portal vein tumor thrombosis--a complete remission achieved with dual treatment of surgery plus percutaneous isolated hepatic perfusion].
abstract: We herein report a case of advanced hepatocellular carcinoma (HCC) with Vp4 portal vein thrombosis (PVTT). All of the hepatic tumors have completely disappeared for more than two years by a dual treatment with reductive surgery plus percutaneous isolated hepatic perfusion (PIHP). A 68-year-old man was referred to our institution in May 2009. The abdominal CT scan demonstrated massive HCC in the right robe of the liver with PVTT reaching the portal trunk (Vp4). We semi-electively performed a right hepatectomy together with thrombectomy of the PVTT. Subsequently, we underwent a PIHP (doxorubicin 90 mg/m2). This resulted in normalization of serum AFP and PIVKA-II levels. Dual treatment is considered to be the strongest therapeutic modality for multiple advanced HCC with severe PVTT.
authors.affiliation: Dept. of Surgery, Kobe University Hospital.
authors.forename: Masashi
authors.initials: M
authors.lastname: Chuma
authors.forename: Takumi
authors.initials: T
authors.lastname: Fukumoto
authors.forename: Nobuya
authors.initials: N
authors.lastname: Kusunoki
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tsuchida
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kido
authors.forename: Masanori
authors.initials: M
authors.lastname: Takahashi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tsugawa
authors.forename: Masahide
authors.initials: M
authors.lastname: Awazu
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kataoka
authors.forename: Ippei
authors.initials: I
authors.lastname: Matsumoto
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Hori
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kuroda
authors.forename: Yonson
authors.initials: Y
authors.lastname: Ku
mesh_terms: D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000473:pathology* / Q000628:therapy*; D010478:Chemotherapy, Cancer, Regional Perfusion; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy*; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D009360:Neoplastic Cells, Circulating; D011169:Portal Vein
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin; D004317:Doxorubicin