title: EROS: Better than SAXS!
abstract: Revealing the three-dimensional organization of large dynamic protein complexes in solution is challenging. To tackle this problem, Różycki and colleagues (2011) design a method combining small angle X-ray scattering (SAXS) data with the results of computer simulations. Their study offers new insights into the conformational transition induced by salt that occurs in an endosome-associated ESCRT-III CHMP3 domain.
authors.affiliation: Center for Proteomics and Department of Pharmacology, Case Western Reserve University, Biomedical Research Building, 10900 Euclid Avenue, Cleveland, OH 44106, USA. sichun.yang@case.edu
authors.forename: Sichun
authors.initials: S
authors.lastname: Yang
authors.forename: Benoît
authors.initials: B
authors.lastname: Roux