title: Efficacy of eprinomectin pour-on against Dictyocaulus arnfieldi infection in donkeys (Equus asinus).
abstract: A trial to assess the efficacy of eprinomectin (EPM) against the lungworm Dictyocaulus arnfieldi was carried out on 15, naturally-infected donkeys. Ten animals were treated with a 'pour-on' EPM preparation (at a dose of 0.5 mg/kg bodyweight), and five animals acted as controls. Faecal larval counts were carried out two days before treatment, on day of treatment and 7, 14, 21 and 28 days post-treatment with the anthelmintic. EPM was 100% effective in eliminating faecal larvae from day 7, until the end of study at day 28. No adverse drug-reactions or side-effects were observed in any of the treated donkeys.
authors.affiliation: Department of Pathology and Animal Health, Faculty of Veterinary Medicine, University of Naples Federico II, Naples, Italy. vincenzo.veneziano@unina.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Veneziano
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Loria
authors.forename: Roberto
authors.initials: R
authors.lastname: Masucci
authors.forename: Rossella
authors.initials: R
authors.lastname: Di Palo
authors.forename: Emanuele
authors.initials: E
authors.lastname: Brianti
authors.forename: Cengiz
authors.initials: C
authors.lastname: Gokbulut
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage*; D004021:Dictyocaulus / Q000187:drug effects* / Q000302:isolation & purification; D004022:Dictyocaulus Infections / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D018397:Equidae / Q000469:parasitology*; D005243:Feces / Q000469:parasitology; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D007559:Ivermectin; C101434:eprinomectin