title: Cytokine signaling exposed.
abstract: In this issue, Lupardus et al. (2011) provide images, obtained by electron microscopy, of a complete cytokine signaling complex, offering clues into the mechanism by which binding of cytokines to their cognate receptors triggers trans-phosphorylation and activation of Janus kinases.
authors.affiliation: Structural Biology Program, Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA. stevan.hubbard@med.nyu.edu
authors.forename: Stevan R
authors.initials: SR
authors.lastname: Hubbard