Embryonal rhabdomyosarcoma of the cervix and appendiceal carcinoid tumor.
BACKGROUND
Rhabdomyosarcomas, particularly those of gynecologic origin, are very rare in adults. As a result, there is little literature on the optimal staging procedure and treatment modalities for this population.


METHODS
A 43-year-old woman presented with a long-standing history of menorrhagia and was subsequently diagnosed with embryonal rhabdomyosarcoma of the cervix. She underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy, lymph node dissection, omentectomy, and appendectomy, which also revealed a synchronous tubular carcinoid tumor of appendiceal origin. Plans for treatment involve adjuvant chemotherapy with vincristine, dactinomycin, and cyclophosphamide.


CONCLUSIONS
This case adds to the small body of literature surrounding cervical embryonal rhabdomyosarcoma in women over the age of 40 years and proposes that appendectomy be considered during surgical management.
From Weill Cornell Medical College; New York Presbyterian Hospital-Weill Cornell Medical Center; the Department of Pathology, New York Presbyterian Hospital-Weill Cornell Medical Center; and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.
Brandi N
BN
Adams
Justin S
JS
Brandt
Kristina
K
Loukeris
Kevin
K
Holcomb
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D001062:Appendectomy; D001063:Appendiceal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D001065:Appendix / Q000473:pathology / Q000601:surgery; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018233:Rhabdomyosarcoma, Embryonal / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D014750:Vincristine / Q000627:therapeutic use
D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide
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