Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.
Cupredoxins are small proteins that contain type I copper centers, which are ubiquitous in nature. They function as electron transfer shuttles between proteins. This review of the structure and properties of native cupredoxins, and those modified by site-directed mutagenesis, illustrates how these proteins may have evolved to specifically bind copper, develop recognition sites for specific redox partners, tune redox potential for a particular function, and allow for efficient electron transfer through the protein matrix. This is relevant to the general understanding of the roles of metals in energy metabolism, respiration and photosynthesis.
Department of Biochemistry, University of Mississippi Medical Center, 2500 N. State St., Jackson, MS 39216-4505, USA.
Moonsung
M
Choi
Victor L
VL
Davidson
D001400:Azurin / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D003300:Copper / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D010970:Plastocyanin / Q000737:chemistry / Q000378:metabolism
C050107:cupredoxin; D001400:Azurin; D003300:Copper; D010970:Plastocyanin
J Biol Chem. 1995 Oct 13;270(41):23941-3
7592588
J Inorg Biochem. 2008 Feb;102(2):342-6
17986390
Oncogene. 2004 Mar 25;23(13):2367-78
14981543
J Biol Chem. 1995 Mar 3;270(9):4293-8
7876189
J Mol Biol. 1991 Oct 5;221(3):765-72
1942029
Annu Rev Biophys Biomol Struct. 1992;21:349-77
1326356
J Biol Chem. 1999 Feb 12;274(7):4225-30
9933621
Nature. 1999 Nov 4;402(6757):47-52
10573417
Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11799-804
20547871
Eur J Biochem. 1995 Mar 15;228(3):653-7
7737159
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1339-41
4275396
Annu Rev Biochem. 1996;65:537-61
8811189
J Am Chem Soc. 2001 Mar 14;123(10):2405-13
11456890
Biochemistry. 1999 Sep 28;38(39):12675-80
10504237
Protein Sci. 1996 Nov;5(11):2175-83
8931136
Biochemistry. 2005 May 17;44(19):7200-6
15882058
Biochemistry. 2003 Feb 18;42(6):1772-6
12578392
Arch Biochem Biophys. 2005 Dec 1;444(1):27-33
16289023
Biochemistry. 2007 Jul 24;46(29):8561-8
17602663
J Am Chem Soc. 2002 Nov 20;124(46):13698-708
12431099
J Am Chem Soc. 2004 Jun 30;126(25):8010-9
15212551
Nucleic Acids Res. 1988 Nov 25;16(22):10717-32
3060848
Biochemistry. 2002 Mar 19;41(11):3613-9
11888277
J Biol Inorg Chem. 2004 Mar;9(2):231-7
14735334
Biochim Biophys Acta. 2000 Jan 3;1456(1):5-26
10611452
Biochemistry. 2009 Oct 6;48(39):9174-84
19715303
J Bioenerg Biomembr. 1995 Jun;27(3):295-302
8847343
Biochemistry. 2003 Sep 9;42(35):10396-405
12950166
J Am Chem Soc. 2003 Jul 23;125(29):8760-8
12862470
J Mol Biol. 1986 Nov 20;192(2):361-87
3560221
Biochemistry. 1995 Sep 26;34(38):12249-54
7547967
Biochemistry. 1996 Nov 12;35(45):14035-9
8916887
Biochemistry. 2001 Jan 23;40(3):837-46
11170402
J Biomol Struct Dyn. 2007 Oct;25(2):157-64
17718594
Biochemistry. 2007 Oct 2;46(39):11137-46
17824674
J Am Chem Soc. 2002 Apr 17;124(15):4093-6
11942848
Biochemistry. 2000 Apr 25;39(16):4924-8
10769151
Acc Chem Res. 2008 Jun;41(6):730-8
18442271
Adv Protein Chem. 2001;58:95-140
11665494
Biochemistry. 1994 May 17;33(19):5696-701
8180195
Cell Mol Life Sci. 2005 Sep;62(18):2050-66
16091847
Biochemistry. 1986 May 6;25(9):2431-6
3718960
Chem Rev. 1996 Nov 7;96(7):2563-2606
11848837
J Inorg Biochem. 2002 Feb;88(3-4):375-80
11897353
Biochemistry. 1998 Jun 30;37(26):9570-8
9649340
Eur J Biochem. 1994 Aug 1;223(3):711-8
8055947
Biochemistry. 1992 Jun 2;31(21):4959-64
1599920
Biochemistry. 2007 Feb 20;46(7):1799-810
17249693
Biochemistry. 1997 Oct 21;36(42):12733-8
9335529
J Biomol Struct Dyn. 2008 Apr;25(5):543-51
18282009
Chem Rev. 2004 Feb;104(2):419-58
14871131
Biochemistry. 1998 May 19;37(20):7371-7
9585551
Biochemistry. 2004 Jul 27;43(29):9372-80
15260480
Biochemistry. 1995 Jan 24;34(3):816-23
7827040
J Biol Chem. 1988 Oct 5;263(28):13987-90
3170535
Eur J Biochem. 1992 May 1;205(3):1123-9
1576995
Acc Chem Res. 2000 Feb;33(2):87-93
10673316
J Mol Biol. 1983 Sep 15;169(2):521-63
6620385
Science. 1991 May 10;252(5007):817-24
2028257
Protein Sci. 1993 May;2(5):739-52
8495197
Biochemistry. 1997 Oct 28;36(43):13160-79
9341204
Biochemistry. 1996 Jun 25;35(25):8120-5
8679563
J Am Chem Soc. 2006 Dec 13;128(49):15608-17
17147368
J Biol Chem. 1999 Oct 22;274(43):30365-9
10521412
Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4246-9
9113974
Acta Crystallogr D Biol Crystallogr. 1994 May 1;50(Pt 3):263-70
15299437
J Biomol NMR. 2001 Mar;19(3):199-208
11330808
Biosens Bioelectron. 2005 Jun 15;20(12):2517-54
15854824
J Biol Chem. 1987 Nov 5;262(31):14983-9
3667619
Biochemistry. 2006 Nov 14;45(45):13500-10
17087503
Biochemistry. 1998 Dec 8;37(49):17128-36
9860825
Biochemistry. 2007 Feb 20;46(7):1900-12
17295442
J Biol Chem. 1996 Apr 19;271(16):9177-80
8621571
Protein Sci. 1998 Sep;7(9):1915-29
9761472
Science. 1994 Apr 1;264(5155):86-90
8140419
Adv Protein Chem. 1991;42:145-97
1793005
FEBS Lett. 1986 Oct 27;207(2):239-42
3021532
J Bacteriol. 1994 May;176(10):2922-9
8188594
J Biol Chem. 1985 Nov 25;260(27):14626-9
2997215
Biochemistry. 2004 Jul 27;43(29):9381-9
15260481
J Biol Chem. 1986 Jul 5;261(19):8577-80
3013855
Structure. 1998 Mar 15;6(3):323-35
9551554
J Am Chem Soc. 2001 Oct 31;123(43):10444-53
11673974
Nature. 2009 Nov 5;462(7269):113-6
19890331