The antithrombotic effects of organic nitrates.
The antianginal mechanism of organic nitrates is attributed to their vasodilatory action(s). In this article, the authors review the in vitro and in vivo data implicating an antiplatelet mechanism of action for organic nitrates that may contribute to their antiischemic properties.
Cardiovascular Divisions, Brigham and Women's Hospital, Brockton/West Roxbury Veterans Administration Medical Center, Harvard Medical School, Boston, MA 02115, USA.
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JS
Stamler
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Loscalzo