Sentinel lymph node detection by an optical method using scattered photons.
We present a new near infrared optical probe for the sentinel lymph node detection, based on the recording of scattered photons. A two wavelengths setup was developed to improve the detection threshold of an injected dye: the Patent Blue V dye. The method used consists in modulating each laser diode at a given frequency. A Fast Fourier Transform of the recorded signal separates both components. The signal amplitudes are used to compute relative Patent Blue V concentration. Results on the probe using phantoms model and small animal experimentation exhibit a sensitivity threshold of 3.2 µmol/L, which is thirty fold better than the eye visible threshold.
Franklin
F
Tellier
Rasata
R
Ravelo
Hervé
H
Simon
Renée
R
Chabrier
Jérôme
J
Steibel
Patrick
P
Poulet
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