[Functional magnetic resonance imaging of cortical changes in a low-grade glioma patient].
BACKGROUND
New methods for studying brain functions have provided the new insights into human brain. It is really possible to study a cortical adaptation in adults who have sustained injury. We reported cortical changes in a left frontal low-grade glioma patient during disease progression and after reoperation by functional magnetic resonance imaging (fMRI).


METHODS
The use of fMRI exams for localisation of eloquent motor and language areas were performed three times in a period of 15 months: seven years after initial tumor resection, eleven months later and three months after the reoperation. The first fMRI demonstrated cortical activation for motor tasks in the expected location of primary motor area while later examinations showed activations of both primary motor areas for right hand movement. The first exam language evaluation showed the left hemisphere dominance for both language tasks, while the second fMRI demonstrated the right hemisphere dominance for complex word generation task, but the left hemisphere remained dominant in simple language task. After the reoperation, language mapping revealed the left hemisphere dominance for both language tasks.


CONCLUSIONS
fMRI evaluation of cortical changes in low-grade glioma patients may additionally optimize and individualize neurosurgical treatment.
Institut za onkologiju Vojvodine, Centar za imidzing dijagnostiku, Sremska Kamenica, Srbija. sveljo.olivera@onk.ns.ac.rs
Olivera
O
Sveljo
Katarina
K
Koprivsek
Milos A
MA
Lucić
Ljubodrag
L
Minić
D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000503:physiopathology* / Q000601:surgery; D002540:Cerebral Cortex / Q000503:physiopathology*; D005910:Glioma / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male