Persistent abnormal value of late potential in Brugada syndrome associated with hypokalemia.
Hypokalemia accentuates the electrocardiographic (ECG) pattern of Brugada syndrome. We report two patients with Brugada syndrome and hypokalemia-induced lethal events. Despite concealing the typical ECG pattern with normalization of serum potassium levels, late potentials were persistently detected by signal-averaged ECG, even at the 18-month follow-up. An implantable cardioverter defibrillator was inserted to prevent sudden cardiac death.
Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-nishi, Yamagata, Japan.
Daisuke
D
Kutsuzawa
Takanori
T
Arimoto
Tetsu
T
Watanabe
Joji
J
Nitobe
Takuya
T
Miyamoto
Takehiko
T
Miyashita
Tetsuro
T
Shishido
Hiroki
H
Takahashi
Satoshi
S
Nishiyama
Isao
I
Kubota
D000200:Action Potentials; D053840:Brugada Syndrome / Q000150:complications* / Q000503:physiopathology; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D006801:Humans; D007008:Hypokalemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011188:Potassium / Q000097:blood
D011188:Potassium
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15655131
Ann Noninvasive Electrocardiol. 2005 Oct;10(4):396-403
16255748
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11345376
J Am Coll Cardiol. 2002 Jun 5;39(11):1799-805
12039494
Pacing Clin Electrophysiol. 2007 Jan;30(1):135-6
17241329
Circ J. 2003 Jan;67(1):93-5
12520160
Pacing Clin Electrophysiol. 2005 Dec;28(12):1350-3
16403168