[Protein kinase LOSK regulates the network of microtubules and cell locomotion].
It has been found that the inhibition of the activity of protein kinase LOSK reduces the ability of cells to the directed movement over the substrate and changes the parameters of the interaction of cells with the substrate. It is suggested that the chaotization of microtubules leads to the stabilization of cell contacts with the substrate and, consequently, to a slowing down of locomotion.
A V
AV
Burakov
E S
ES
Nadezhdina
D000818:Animals; D002465:Cell Movement; D002522:Chlorocebus aethiops; D008870:Microtubules / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000502:physiology*; D014709:Vero Cells
D017346:Protein Serine-Threonine Kinases