Morphometric comparison of the lumbar cancellous bone of sheep, deer, and humans.
To investigate the feasibility of using deer and sheep as animal models for the human spine, we compared the microarchitectural dimensions of the deer and sheep spines and with human data. To this end, we adopted the traditional bone tissue morphometric method, using figure analysis software for quantitative analysis of 2D images of bone tissue. Compared with those of humans, the lumbar cancellous bone of deer and sheep has higher microarchitectural indices, more densely packed bone trabeculae, lower porosity, and higher bone mass. Despite specific differences in various morphologic indices, the anisotropy of lumbar cancellous bone in deer and sheep shows the same trend as that in humans.
Department of Anatomy, Norman Bethune Medical School, Jilin University, Department of Hand Surgery, First Affiliated Hospital of Jilin University, Changchun, Jilin Province, China.
Yang
Y
Wang
Guomin
G
Liu
Ting
T
Li
Yanlong
Y
Xiao
Qing
Q
Han
Randong
R
Xu
Youqiong
Y
Li
D000818:Animals; D003670:Deer / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000648:ultrastructure*; D008297:Male; D012756:Sheep / Q000033:anatomy & histology*; D012984:Software; D013045:Species Specificity
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