[Pharmacological treatment of nystagmus].
Nystagmus can be associated with strong discomfort due to oscillopsia, blurry vision and dizziness. Since generally no curative treatment methods exist, studies focus on potential pharmaceuticals to dampen the nystagmus. An overview is given on which forms of nystagmus can be treated with what kind of pharmacological substances and their possible mechanism of nystagmus dampening. Controlled studies found gabapentin and memantine to be effective in acquired pendular nystagmus and early-onset idiopathic nystagmus, and an efficacy of 4-aminopyridine in downbeat nystagmus.
Universitäts-Augenklinik Freiburg, Killianstr. 5, 79106 Freiburg, Deutschland. christina.beisse@uniklinik-freiburg.de
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Pieh-Beisse
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Lagrèze
D015761:4-Aminopyridine / Q000627:therapeutic use*; D000588:Amines / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use; D001418:Baclofen / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D015259:Dopamine Agents / Q000627:therapeutic use; D000077206:Gabapentin; D006801:Humans; D008559:Memantine / Q000627:therapeutic use*; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D009759:Nystagmus, Pathologic / Q000188:drug therapy* / Q000517:prevention & control*; D026902:Potassium Channel Blockers / Q000627:therapeutic use; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D015259:Dopamine Agents; D009125:Muscle Relaxants, Central; D026902:Potassium Channel Blockers; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin; D015761:4-Aminopyridine; D001418:Baclofen; D008559:Memantine
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