Go6976 abrogates GPVI-mediated platelet functional responses in human platelets through inhibition of Syk.
T M
TM
Getz
A
A
Mayanglambam
J L
JL
Daniel
S P
SP
Kunapuli
D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology*; D020013:Calcium Signaling / Q000187:drug effects; D002227:Carbazoles / Q000494:pharmacology*; D002352:Carrier Proteins / Q000494:pharmacology; D003435:Crotalid Venoms / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D047908:Intracellular Signaling Peptides and Proteins / Q000037:antagonists & inhibitors* / Q000097:blood; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000097:blood; D037181:Lectins, C-Type; D010455:Peptides / Q000494:pharmacology; D010980:Platelet Membrane Glycoproteins / Q000502:physiology*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors / Q000097:blood; D047428:Protein Kinase Inhibitors / Q000494:pharmacology; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000097:blood; D000072377:Syk Kinase
D002227:Carbazoles; D002352:Carrier Proteins; D003435:Crotalid Venoms; D047908:Intracellular Signaling Peptides and Proteins; D007527:Isoenzymes; D037181:Lectins, C-Type; D010455:Peptides; D010980:Platelet Membrane Glycoproteins; D047428:Protein Kinase Inhibitors; C435908:collagen-related peptide; C098341:platelet membrane glycoprotein VI; C081021:Go 6976; C028890:convulxin; D011505:Protein-Tyrosine Kinases; C000606896:SYK protein, human; D000072377:Syk Kinase; D011493:Protein Kinase C
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