Fast and flexible synthesis of pantothenic acid and CJ-15,801.
The fast and efficient syntheses of pantothenic acid and the antiparasitic agent CJ-15,801 have been achieved starting from a common imide unit through the selective manipulation of enamide intermediates.
WestCHEM, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, United Kingdom.
Alan L
AL
Sewell
Mathew V J
MV
Villa
Mhairi
M
Matheson
William G
WG
Whittingham
Rodolfo
R
Marquez
D007094:Imides / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D010205:Pantothenic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D010963:Plasmodium falciparum / Q000187:drug effects; D013237:Stereoisomerism
C449028:CJ-15,801; D007094:Imides; D010205:Pantothenic Acid