[Toxic hepatitis triggered by green tea].
Green tea is associated with various beneficial health effects, but several cases of hepatotoxic side effects have been reported. We present the first Danish case of toxic hepatitis following the consumption of 4-6 cups of green tea per day for six months. Green tea's main chemical component is epigallocatechin gallate (EGCG). Animal studies have shown that EGCG accumulated in the liver is most toxic when consumed fasting and that it causes greater hepatotoxicity upon repeated administration. Green tea hepatotoxicity should be kept in mind and cases are notifiable to the food authorities.
Medicinsk Afdeling, Glostrup Hospital, Denmark. johan.rohde@gmail.com
Johan
J
Rohde
Claire
C
Jacobsen
Hans
H
Kromann-Andersen
D000818:Animals; D000975:Antioxidants / Q000009:adverse effects / Q000633:toxicity; D028241:Camellia sinensis / Q000009:adverse effects*; D002392:Catechin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000633:toxicity; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000187:drug effects; D013662:Tea / Q000009:adverse effects*
D000975:Antioxidants; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate