Validity of the Berlin Questionnaire in identifying obstructive sleep apnea syndrome when administered to the informants of stroke patients.
Given the high prevalence of sleep-disordered breathing (SDB) in stroke and its importance as a vascular risk factor, a clinical instrument to assess its incidence would be useful. Acute stroke patients (n=121) were stratified into high- and low-risk groups for SDB using a modified Berlin Questionnaire (BQ) administered to the informants who were living with the patient. After a minimum of 4 weeks from stroke onset, patients who were fit underwent overnight polysomnography (PSG). On stratifying risk of obstructive sleep apnea (OSA) in these patients based on the BQ, 53% belonged to the high-risk group and 47% belonged to the low-risk group. There was poor correlation between the clinical questionnaire results and PSG findings, with sensitivity of 66.7%, specificity of 55.6%, a positive predictive value of 63.4%, and a negative predictive value of 58.8%.
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India. srijitheshpr@rediffmail.com
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Srijithesh
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Shukla
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Srivastav
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Goyal
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Singh
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Behari
D017028:Caregivers; D006801:Humans; D007194:India / Q000453:epidemiology; D008875:Middle Aged; D017286:Polysomnography; D015995:Prevalence; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000453:epidemiology*; D020521:Stroke / Q000150:complications*; D011795:Surveys and Questionnaires