Motor cortex electric stimulation for the treatment of neuropathic pain.
OBJECTIVE
Motor cortex stimulation (MCS) is considered to be an effective treatment for chronic neuropathic pain. The aim of the present study was to assess the efficacy of MCS for treating neuropathic pain.


METHODS
27 patients with chronic neuropathic pain were operated. Electrodes were implanted with the use of an stereotactic frame. Electrophysiological evaluations (motor stimulation and somatosensory evoked potentials) were performed, with guidance by means of three-dimensional reconstruction of magnetic resonance images of the brain. 10 patients (37%) presented central neuropathic pain (post-stroke pain) and 17 others (63%) presented peripheral neuropathic pain (brachial plexus avulsion, phantom limb pain or trigeminal pain).


RESULTS
In 15 patients (57.7%) the pain relief was 50% or more; while in ten patients (38.5%), more than 60% of the original pain was relieved. No differences were found in relation to central and peripheral neuropathic pain (p=0.90), pain location (p=0.81), presence of motor deficit (p=0.28) and pain duration (p=0.72). No major complications were observed.


CONCLUSIONS
MCS was efficient for treating patients presenting chronic central or peripheral neuropathic pain.
Department of Neurosurgery, Roger Salengro Hospital, University of Lille, France. neurowalter@hotmail.com
Walter J
WJ
Fagundes-Pereyra
Manoel Jacobsen
MJ
Teixeira
Nicolas
N
Reyns
Gustavo
G
Touzet
Sérgio
S
Dantas
Emmanuelle
E
Laureau
Serge
S
Blond
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004599:Electric Stimulation Therapy / Q000379:methods*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex; D009437:Neuralgia / Q000503:physiopathology / Q000628:therapy*; D010147:Pain Measurement; D016896:Treatment Outcome