Towards energetically viable asymmetric deprotonations: selectivity at more elevated temperatures with C2-symmetric magnesium bisamides.
A novel chiral magnesium bisamide has enabled the development of effective asymmetric deprotonation protocols at substantially more elevated temperatures. This new, structurally simple, C(2)-symmetric magnesium complex displays excellent levels of asymmetric efficiency and energy reduction in the synthesis of enantioenriched enol silanes.
Department of Pure and Applied Chemistry, WestCHEM, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK.
Linsey S
LS
Bennie
William J
WJ
Kerr
Michael
M
Middleditch
Allan J B
AJ
Watson