Flavonoids from the aerial parts of Macrothelypteris torresiana.
Two new flavone derivatives (1 and 2) were isolated from the aerial parts of Macrothelypteris torresiana, along with four known flavonoids: protoapigenin, apigenin, kaempferol and quercetin. The structures were determined on the basis of spectroscopic data. Compound 1 showed weak cytotoxic activity against human tumour cell lines HepG₂ , MCF₇ and K562.
College of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.
Wei
W
Fang
Jinlan
J
Ruan
Yaling
Y
Cai
Anhua
A
Wei
Daonian
D
Zhou
Wenting
W
Zhang
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D003512:Cyclohexanones / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology*; D047309:Flavones / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D035261:Plant Components, Aerial / Q000737:chemistry*; D029621:Polypodiaceae / Q000737:chemistry*
C558426:2-(cis-1,2-dihydroxy 4-oxo-cyclohex-5-enyl)-5,7-dihydroxychromone; C560352:2-(trans-1,4-dihydroxy-cyclohexyl)-5,7-dihydroxychromone; D000972:Antineoplastic Agents, Phytogenic; D003512:Cyclohexanones; D047309:Flavones