[Renal failure in Tunisian patients with type 2 diabetes: frequency and related factors].
BACKGROUND
Frequent screening of renal failure and good glycaemic control in diabetic patients can avoid this severe complication.


OBJECTIVE
To evaluate the frequency of renal failure and the associated risk factors among type 2 diabetic Tunisian in-patients. Glomerular filtration rate was estimated using the Cockcroft-Gault formula. Renal failure was diagnosed on figure of glomerular filtration rate inferior than 60 ml/min.


RESULTS
Six hundred eighty-nine patients were included. The sex ratio was 0.65. The mean age was 60 ± 11 years. The frequency of renal failure was 19.8% (137 patients) with dominance of a moderate form defined by a glomerular filtration rate between 30 and 59 ml/min (82.5% of patients). Patients with renal failure were older and less obese than diabetic patients without this complication (p<0.00001 and 0.02 respectively). The duration of both diabetes and hypertension was higher in presence of renal failure (p=0.0001 and p<0.001 respectively). Patients with renal failure had more often hypertension and dyslipidemia than patients with normal renal function (p<0.001 and p=0.01 respectively). A personal history of severe retinopathy treated by laser, of coronary disease or of stroke was significantly associated to renal failure (p=0.002, p<0.0001 and p=0.001 respectively).


CONCLUSIONS
The frequency of renal failure observed in Tunisian patients diagnosed with type 2 diabetes is high. Hypertension and dyslipidemia should be carefully treated to prevent or delay the evolution to the renal failure.
Service d'endocrinologie, Institut national de nutrition et de technologies alimentaires, Tunis, Tunisie.
Chiraz
C
Bouzid
Hajer
H
Smida
Anissa
A
Kacem
Zinet
Z
Turki
Leila
L
Ben Salem
Chiheb
C
Ben Rayana
Ben Claude
BC
Slama
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000453:epidemiology*; D012189:Retrospective Studies; D014416:Tunisia / Q000453:epidemiology; D055815:Young Adult