[Single nucleotide polymorphism of +276 g > t adiponectin (APM1) gene in donors of Kharkiv population].
Polymorphism of adiponectine (APM1) gene in +276G > T position was studied. For this research we used blood samples of 103 donors (men/women: 65/38; 70 Ukrainian, 33 Russian) - habitants of Kharkiv. Frequencies of T and G alleles were pT = 0.55 and pG = 0.45 in a general group. They did not meaningfully differentiate either for men and women or for Russians and Ukrainians. Distribution of genotypes did not correspond to Hardy-Weinberg equilibrium: share of heterozygotes was 1.55 times higher than selectively-neutral value, share of TT homozygote is 0.55, and GG homozygote is 0.33 of equilibrium value.
L A
LA
Atramentova
V V
VV
Poltorak
T V
TV
Tyzhnenko
M Iu
MIu
Gorshunskaia
A K
AK
Pocherniaev
D052242:Adiponectin / Q000235:genetics; D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data; D002947:Cities; D004247:DNA / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D005820:Genetic Testing; D006579:Heterozygote; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D012426:Russia / Q000208:ethnology; D014455:Ukraine / Q000453:epidemiology; D055815:Young Adult
C499918:ADIPOQ protein, human; D052242:Adiponectin; D004247:DNA