[Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy].
Experimental data on the influence of omnipak-350 introduction in a dose of 20 g/kg on the glutathione exchange processes and lipide peroxidation in kidneys, liver and erythrocytes of white outbred rats are presented. The possibility of using cytoflavin for correcting x-ray contrast agent-induced disorders in the natural cytoprotective system is shown. Probable mechanisms of the cytoprotective effect of the proposed pharmacological treatment are discussed.
S N
SN
Karpishchenko
S N
SN
Zheregelia
S I
SI
Glushkov
D000818:Animals; D003287:Contrast Media / Q000009:adverse effects* / Q000494:pharmacology; D019610:Cytoprotection / Q000187:drug effects*; D004338:Drug Combinations; D005486:Flavin Mononucleotide / Q000494:pharmacology*; D007290:Inosine Diphosphate / Q000494:pharmacology*; D007472:Iohexol / Q000009:adverse effects* / Q000494:pharmacology; D007674:Kidney Diseases / Q000139:chemically induced* / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D008297:Male; D009536:Niacinamide / Q000494:pharmacology*; D051381:Rats; D013386:Succinates / Q000494:pharmacology*
D003287:Contrast Media; D004338:Drug Combinations; D013386:Succinates; C507879:cytoflavin; D009536:Niacinamide; D007472:Iohexol; D005486:Flavin Mononucleotide; D007290:Inosine Diphosphate