Spatial constancy mechanisms in motor control.
The success of the human species in interacting with the environment depends on the ability to maintain spatial stability despite the continuous changes in sensory and motor inputs owing to movements of eyes, head and body. In this paper, I will review recent advances in the understanding of how the brain deals with the dynamic flow of sensory and motor information in order to maintain spatial constancy of movement goals. The first part summarizes studies in the saccadic system, showing that spatial constancy is governed by a dynamic feed-forward process, by gaze-centred remapping of target representations in anticipation of and across eye movements. The subsequent sections relate to other oculomotor behaviour, such as eye-head gaze shifts, smooth pursuit and vergence eye movements, and their implications for feed-forward mechanisms for spatial constancy. Work that studied the geometric complexities in spatial constancy and saccadic guidance across head and body movements, distinguishing between self-generated and passively induced motion, indicates that both feed-forward and sensory feedback processing play a role in spatial updating of movement goals. The paper ends with a discussion of the behavioural mechanisms of spatial constancy for arm motor control and their physiological implications for the brain. Taken together, the emerging picture is that the brain computes an evolving representation of three-dimensional action space, whose internal metric is updated in a nonlinear way, by optimally integrating noisy and ambiguous afferent and efferent signals.
Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, PO Box 9104, NL-6500 HE Nijmegen, The Netherlands. p.medendorp@donders.ru.nl
W Pieter
WP
Medendorp
D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*; D014785:Vision, Ocular / Q000502:physiology*
J Neurophysiol. 1998 Nov;80(5):2785-9
9819282
J Neurophysiol. 2007 Feb;97(2):1738-55
17093130
Curr Biol. 2005 Oct 25;15(20):R839-40
16243024
J Neurophysiol. 2008 May;99(5):2708-18
18367698
Neuropsychologia. 2006;44(13):2766-73
16321407
Neuropsychologia. 2006;44(13):2700-16
16455113
J Neurophysiol. 2010 Jan;103(1):117-39
19846615
J Neurophysiol. 1996 Dec;76(6):3617-32
8985862
J Neurosci. 2006 Apr 19;26(16):4188-97
16624939
Science. 1980 Jun 6;208(4448):1163-5
6769161
J Neurosci. 2004 Oct 20;24(42):9291-302
15496665
J Neurophysiol. 2006 May;95(5):2751-67
16291805
Exp Brain Res. 1998 Sep;122(1):93-100
9772116
Annu Rev Neurosci. 2002;25:189-220
12052908
J Neurophysiol. 2001 Oct;86(4):2112-7
11600667
Nat Rev Neurosci. 2004 Mar;5(3):218-28
14976521
Exp Brain Res. 2001 Mar;137(1):45-57
11310171
J Neurosci. 2009 Mar 11;29(10):3026-35
19279239
Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):4026-31
11904446
J Neurophysiol. 2008 Apr;99(4):1799-809
18256164
J Neurophysiol. 1995 May;73(5):1988-2003
7623096
Neuron. 2005 Oct 6;48(1):149-58
16202715
J Neurophysiol. 2004 Mar;91(3):1424-41
14523076
J Neurosci. 2003 Jul 16;23(15):6209-14
12867504
Nat Neurosci. 2008 Oct;11(10):1223-30
18776895
Science. 2008 Aug 8;321(5890):851-4
18687968
J Neurophysiol. 2009 Mar;101(3):1321-33
19118112
Behav Brain Res. 2005 Sep 8;163(2):194-203
15970337
Science. 1972 Dec 15;178(4066):1217-9
4637810
J Comp Physiol Psychol. 1950 Dec;43(6):482-9
14794830
Exp Brain Res. 2007 May;179(2):263-90
17136526
Annu Rev Neurosci. 2008;31:317-38
18558858
Cereb Cortex. 2007 Oct;17(10):2283-92
17215478
J Vis. 2009 Feb 09;9(2):9.1-15
19271919
J Neurophysiol. 2004 Oct;92(4):2380-93
15190097
Neuroreport. 2007 Aug 6;18(12):1207-13
17632269
J Neurophysiol. 2007 May;97(5):3256-68
17329621
Exp Brain Res. 2006 Oct;174(3):528-43
16832684
PLoS Comput Biol. 2008 Feb;4(2):e31
18282086
Vision Res. 1976 Jan;16(1):99-106
1258395
Neuron. 2003 Jul 17;39(2):361-73
12873391
Percept Psychophys. 2005 Apr;67(3):495-512
16119397
Exp Brain Res. 1994;102(1):95-109
7895803
Science. 2001 Nov 9;294(5545):1350-4
11701930
J Neurosci. 2007 Mar 21;27(12):3268-73
17376987
J Neurosci. 1998 Feb 15;18(4):1583-94
9454863
Behav Brain Res. 2006 Apr 25;169(1):150-61
16442641
Vision Res. 2008 Sep;48(20):2070-89
18513781
J Neurosci. 2003 Sep 3;23(22):8135-42
12954876
Nat Neurosci. 2007 May;10(5):640-6
17396123
J Comp Neurol. 1985 Nov 15;241(3):357-81
4086661
J Neurophysiol. 2005 Aug;94(2):1212-24
15857965
J Neurophysiol. 2004 Apr;91(4):1608-19
14668290
J Neurophysiol. 2007 Feb;97(2):1209-20
17135474
J Neurophysiol. 1995 Jan;73(1):280-97
7714572
J Neurophysiol. 2001 Feb;85(2):539-44
11160491
Annu Rev Neurosci. 2008;31:69-89
18284371
J Neurophysiol. 2003 May;89(5):2564-76
12740406
Exp Brain Res. 1992;89(2):425-34
1623984
Exp Brain Res. 2001 Nov;141(1):33-51
11685409
J Neurophysiol. 2008 May;99(5):2281-90
18353912
Neuroreport. 1999 Nov 26;10(17):3479-83
10619629
Nat Rev Neurosci. 2002 Sep;3(9):741-7
12209122
J Neurosci. 2000 Aug 1;20(15):5835-40
10908625
J Neurophysiol. 2009 Aug;102(2):805-16
19439678
Eur J Neurosci. 2009 Sep;30(6):1151-61
19735295
J Neurosci. 2008 Sep 3;28(36):8968-72
18768690
J Neurosci. 2002 Jan 1;22(1):RC196
11756525
J Neurophysiol. 2008 Dec;100(6):2981-96
18842952
J Neurophysiol. 2007 Jul;98(1):537-44
17442766
Cereb Cortex. 2005 Oct;15(10):1547-60
15746004
Exp Brain Res. 1988;70(1):216-20
3402565
Exp Brain Res. 2006 Sep;174(1):60-73
16565811
Nature. 2006 Nov 16;444(7117):374-7
17093408
Invest Ophthalmol. 1972 Jun;11(6):518-24
5032205
J Neurosci. 1990 Apr;10(4):1176-96
2329374
J Neurophysiol. 2006 Sep;96(3):1676-82
16760354
Annu Rev Neurosci. 1997;20:25-42
9056706
Nature. 2002 Sep 12;419(6903):157-62
12226663
Naturwissenschaften. 1983 Jun;70(6):272-81
6877388
Neural Netw. 1998 Oct;11(7-8):1229-1240
12662746
Brain. 1990 Dec;113 ( Pt 6):1857-71
2276048
J Neurophysiol. 2006 Apr;95(4):2692-7
16371458
J Exp Biol. 1989 Sep;146:195-207
2689561
J Neurophysiol. 2000 Jan;83(1):625-9
10634901
J Neurophysiol. 2005 Aug;94(2):1372-84
15817644
J Neurophysiol. 2005 Dec;94(6):4300-13
16107519
J Neurophysiol. 2004 Jul;92(1):10-9
15212434
J Neurophysiol. 2008 Nov;100(5):2507-14
18768640
J Neurophysiol. 2000 Jul;84(1):11-27
10899179
Exp Brain Res. 1995;106(1):123-34
8542968
Exp Brain Res. 1999 Mar;125(1):50-60
10100976
J Neurophysiol. 2005 Jul;94(1):734-40
15788514
J Neurophysiol. 1990 Aug;64(2):575-81
2213134
Science. 2002 May 24;296(5572):1480-2
12029137
Curr Opin Neurobiol. 2006 Apr;16(2):205-12
16563735
J Neurophysiol. 2005 Jul;94(1):722-33
15788513
Exp Brain Res. 2006 Mar;169(4):532-48
16374631
Science. 1999 Jul 9;285(5425):257-60
10398603
J Neurophysiol. 2005 Mar;93(3):1510-22
15483070
J Neurophysiol. 2005 Jul;94(1):468-78
15716372
J Neurophysiol. 2006 Mar;95(3):1645-55
16291802
Nature. 1998 Aug 27;394(6696):887-91
9732870
Neuroreport. 2002 Aug 27;13(12):1563-6
12218706
Nat Rev Neurosci. 2005 Dec;6(12):966-76
16340956
J Neurophysiol. 2005 Aug;94(2):1432-42
15857971
Annu Rev Neurosci. 2008;31:125-50
18338968
Exp Brain Res. 2005 Aug;164(4):431-41
15895218
J Comput Neurosci. 2008 Apr;24(2):157-78
17636448
J Neurophysiol. 2008 Feb;99(2):915-30
18094098
J Neurosci. 2006 Sep 13;26(37):9376-84
16971521
Science. 1984 Jul 13;225(4658):205-8
6610215
Annu Rev Neurosci. 1999;22:319-49
10202542
Trends Cogn Sci. 2008 Dec;12(12):466-73
18951831
Nat Neurosci. 2009 Aug;12(8):1056-61
19597495
Exp Brain Res. 1999 May;126(1):19-30
10333004
Science. 1992 Jan 3;255(5040):90-2
1553535
J Neurosci. 2008 Aug 20;28(34):8397-405
18716198
Neuroscience. 2008 Oct 28;156(4):801-18
18786618
J Neurophysiol. 1986 Jul;56(1):196-207
3746396
Nature. 2003 Mar 6;422(6927):76-80
12621435
Nat Neurosci. 2006 Nov;9(11):1432-8
17057707
Neuroreport. 2002 Apr 16;13(5):633-6
11973460
Prog Brain Res. 2008;171:467-73
18718342
Exp Brain Res. 2003 Aug;151(4):501-13
12830343
Curr Biol. 2009 Sep 29;19(18):1555-60
19699091
J Neurosci. 2009 Sep 16;29(37):11461-70
19759295
J Neurophysiol. 2007 Apr;97(4):2958-64
17287442
Ann N Y Acad Sci. 2009 May;1164:19-28
19645876
Biol Cybern. 2007 Apr;96(4):389-404
17146661
Cereb Cortex. 2003 Oct;13(10):1009-22
12967918
Prog Brain Res. 2001;130:175-90
11480274
J Cogn Neurosci. 2007 Feb;19(2):266-74
17280515
Trends Cogn Sci. 2006 Jul;10(7):319-26
16807063
Curr Opin Neurobiol. 2004 Dec;14(6):698-706
15582371
Nature. 1988 Feb 25;331(6158):679-84
3344044
J Neurophysiol. 2008 May;99(5):2264-80
18337369
J Neurophysiol. 2008 Jun;99(6):2968-84
18400956
J Neurosci. 2008 Oct 1;28(40):10081-9
18829966
Neuropsychologia. 2006;44(13):2589-93
16962619
J Neurophysiol. 2004 Jun;91(6):2670-84
14960558