Mild transition-metal-free amination of fluoroarenes catalyzed by fluoride ions.
Trimethylsilyl-protected heterocycles undergo N-C bond formation with a variety of electron-deficient fluoroarenes catalyzed by fluoride ions. This reaction avoids stoichiometric amounts of base and thus makes N-arylheterocycles accessible in a very mild and transition-metal-free way.
Technische Universität Kaiserslautern, Fachbereich Chemie, Erwin-Schrödinger-Strasse, Geb. 54, 67663 Kaiserslautern, Germany.
Daniel
D
Dehe
Isabel
I
Munstein
Andreas
A
Reis
Werner R
WR
Thiel
D000586:Amination; D002384:Catalysis; D005459:Fluorides / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007477:Ions / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028561:Transition Elements / Q000737:chemistry*
D006571:Heterocyclic Compounds; D006845:Hydrocarbons, Fluorinated; D007477:Ions; D028561:Transition Elements; D005459:Fluorides