[Location of genes in chromosomes: random or not?].
The possibility is discussed that the order of genes in chromosomes is not random but determined by natural selection, i.e., is a selectively valuable character. Cases of long-term conservation of gene linkage or synteny in evolution are presented. Examples and possible mechanisms of nonrandom gene localization in prokaryotic and eukaryotic chromosomes are considered.
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Zakharov
D000818:Animals; D019143:Evolution, Molecular; D005796:Genes / Q000502:physiology*; D015894:Genome, Human / Q000502:physiology*; D006801:Humans; D011387:Prokaryotic Cells