High-speed spectral domain optical coherence tomography using non-uniform fast Fourier transform.
The useful imaging range in spectral domain optical coherence tomography (SD-OCT) is often limited by the depth dependent sensitivity fall-off. Processing SD-OCT data with the non-uniform fast Fourier transform (NFFT) can improve the sensitivity fall-off at maximum depth by greater than 5dB concurrently with a 30 fold decrease in processing time compared to the fast Fourier transform with cubic spline interpolation method. NFFT can also improve local signal to noise ratio (SNR) and reduce image artifacts introduced in post-processing. Combined with parallel processing, NFFT is shown to have the ability to process up to 90k A-lines per second. High-speed SD-OCT imaging is demonstrated at camera-limited 100 frames per second on an ex-vivo squid eye.
Department of Electrical and Computer Engineering, University of British Columbia,  2332 Main Mall, Vancouver, BC V6T 1Z4, Canada.
Kenny K H
KK
Chan
Shuo
S
Tang
Magn Reson Med. 2001 May;45(5):908-15
11323818
Opt Express. 2004 Feb 9;12(3):367-76
19474832
IEEE Trans Biomed Eng. 2004 Jan;51(1):186-90
14723509
Opt Express. 2003 Sep 8;11(18):2183-9
19466106
Opt Express. 2009 Jul 6;17(14):12121-31
19582127
IEEE Trans Med Imaging. 1988;7(3):213-7
18230471
Opt Lett. 2009 Jun 15;34(12):1849-51
19529724
IEEE Trans Med Imaging. 2002 Nov;21(11):1395-401
12575876
J Biomed Opt. 1998 Jan;3(1):21-31
23015002
Appl Opt. 2009 Nov 10;48(32):6365-70
19904337
Rev Sci Instrum. 2008 Nov;79(11):114301
19045902
Opt Express. 2004 May 31;12(11):2435-47
19475080
Opt Lett. 2007 Dec 15;32(24):3525-7
18087530