Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update.
We update an evidence-based clinical practice guideline for the administration of the dissociative agent ketamine for emergency department procedural sedation and analgesia. Substantial new research warrants revision of the widely disseminated 2004 guideline, particularly with respect to contraindications, age recommendations, potential neurotoxicity, and the role of coadministered anticholinergics and benzodiazepines. We critically discuss indications, contraindications, personnel requirements, monitoring, dosing, coadministered medications, recovery issues, and future research questions for ketamine dissociative sedation.
Department of Emergency Medicine, Loma Linda University Medical Center and Children's Hospital, Loma Linda, CA 92354, USA.
Steven M
SM
Green
Mark G
MG
Roback
Robert M
RM
Kennedy
Baruch
B
Krauss
D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000009:adverse effects; D016292:Procedural Sedation / Q000379:methods / Q000592:standards*; D004636:Emergency Service, Hospital / Q000592:standards*; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects; D017410:Practice Guidelines as Topic
D000778:Anesthetics, Dissociative; D007649:Ketamine