Development of an optical imaging platform for functional imaging of small animals using wide-field excitation.
The design and characterization of a time-resolved functional imager using a wide-field excitation scheme for small animal imaging is described. The optimal operation parameters are established based on phantom studies. The performance of the platform for functional imaging and the simultaneous 3D reconstruction of absorption and scattering coefficients is investigated in vitro.
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th Street Troy NY 12180, United States.
Vivek
V
Venugopal
Jin
J
Chen
Xavier
X
Intes
Opt Lett. 2009 Jul 15;34(14):2156-8
19823533
Opt Express. 2009 Aug 17;17(17):14780-90
19687956
Appl Opt. 1999 May 1;38(13):2950-61
18319877
Phys Med Biol. 2010 May 21;55(10):2961-82
20436232
Appl Opt. 2009 Mar 1;48(7):1328-36
19252634
Phys Med Biol. 2006 Apr 21;51(8):2045-53
16585844
Radiol Clin North Am. 2005 Jan;43(1):221-34, xii
15693658
IEEE Trans Med Imaging. 2008 Aug;27(8):1152-63
18672432
Curr Opin Biotechnol. 2005 Feb;16(1):79-88
15722019
Invest Radiol. 2000 Aug;35(8):479-85
10946975
Annu Rev Biomed Eng. 2002;4:235-60
12117758
Opt Express. 2008 Mar 31;16(7):5048-60
18542605
Appl Opt. 2005 Apr 1;44(10):1858-69
15813523
Nat Med. 2003 Jan;9(1):123-8
12514725
J Biomed Opt. 2009 Mar-Apr;14(2):024012
19405742
J Biomed Opt. 2010 Jan-Feb;15(1):016006
20210452
Opt Express. 1999 Apr 12;4(8):299-307
19396286
J Biomed Opt. 2010 Jan-Feb;15(1):017012
20210486
Appl Opt. 1989 Jun 15;28(12):2331-6
20555520
J Biomed Opt. 2005 Jan-Feb;10(1):11013
15847579
Opt Lett. 1998 Jun 1;23(11):882-4
18087373
Med Phys. 2001 Jun;28(6):1115-24
11439481
J Biomed Opt. 2008 Jan-Feb;13(1):011009
18315358
Appl Opt. 2003 Jul 1;42(19):4125-36
12868856
J Biomed Opt. 2009 Nov-Dec;14(6):064010
20059248
J Opt Soc Am A Opt Image Sci Vis. 1994 Oct;11(10):2727-41
7931757
Rev Sci Instrum. 2008 Mar;79(3):034301
18377031
Opt Lett. 2010 Feb 1;35(3):369-71
20125724
Phys Med Biol. 2004 Jun 21;49(12):N155-63
15272687
Appl Opt. 2005 Apr 10;44(11):2082-93
15835357
J Biomed Opt. 2009 May-Jun;14(3):034045
19566337
Opt Lett. 2010 Jul 1;35(13):2121-3
20596166
Opt Lett. 2009 Apr 1;34(7):983-5
19340192
J Biomed Opt. 2003 Jul;8(3):512-6
12880358
J Biomed Opt. 2006 Jan-Feb;11(1):014020
16526897
Opt Express. 2009 Oct 26;17(22):19566-79
19997176