Relationship between myogenic reaction and autoregulation of cerebral circulation.
Dilatation of rat pial arterioles at constant arteriolar wall strain during autoregulation of cerebral circulation was shown by the method of biomicroscopy. Wavelet-analysis of cerebral blood flow oscillations during this period revealed increased oscillation amplitude in the endothelial and neurogenic frequency ranges and unchanged amplitude at myogenic frequency range. These findings probably attest to the leading role of myogenic reaction in the autoregulation.
Laboratory of Molecular Mechanisms of Thrombogenesis and Thrombolysis, Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia. aleksandrina81@mail.ru
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Alexandrin
D000818:Animals; D001160:Arterioles / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure; D001921:Brain / Q000098:blood supply*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D017078:Laser-Doppler Flowmetry; D008297:Male; D008853:Microscopy; D009129:Muscle Tonus / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology*; D051381:Rats