The influence of training status on oxidative stress in young male handball players.
Although exercise-induced oxidative stress receives considerable scientific attention, there is still little information available regarding exercise-induced adaptations of the antioxidant defence system in adolescent and child athletes. The aim of our study was to establish the effects of long-term exercise training on the redox state of adolescents, and to find correlations between elements of redox homeostasis and aerobic power. Thirty-three handball players and 14 non-athletes, 16-19-years old, were subjected to blood sampling to measure levels of nitric oxide (NO; estimated through nitrites (NO₂⁻), superoxide anion radical (O₂⁻), hydrogen peroxide (H₂O₂), lipid peroxidation (estimated through TBARS), superoxide dismutase (SOD) and catalase (CAT). Subjects were also subjected to maximal progressive exercise test to estimate their maximal oxygen consumption (VO₂max). Athletes had significantly (P < 0.05) higher SOD activity and lower CAT activity compared with non-athletes (SOD: 2175.52 ± 362.07 compared with 1172.16 ± 747.40 U/g of hemoglobin x 10³, and CAT: 2.19 ± 0.31 compared with 3.08 ± 0.47 U/g of hemoglobin x 10³). These differences were the most obvious when comparing non-athletes and athletes with poor/average aerobic power. H₂O₂ and TBARS levels differed among subjects with poor, average or good aerobic power (P < 0.01, and P < 0.05, respectively). Sports engagement and aerobic capacity are important factors in inducing changes in redox status.
Department of Physiology, Faculty of Medicine, University of Kragujevac, Svetozara Markovica 69, P.P. 124, 34000 Kragujevac, Republic of Serbia.
Dusica
D
Djordjevic
Dejan
D
Cubrilo
Marija
M
Macura
Nevena
N
Barudzic
Dragan
D
Djuric
Vladimir
V
Jakovljevic
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002374:Catalase / Q000097:blood; D015444:Exercise; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood; D008297:Male; D009569:Nitric Oxide / Q000097:blood; D018384:Oxidative Stress; D013177:Sports; D013482:Superoxide Dismutase / Q000097:blood; D013481:Superoxides / Q000097:blood; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D017392:Thiobarbituric Acid Reactive Substances; D013481:Superoxides; D009569:Nitric Oxide; D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase
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