HIV-associated dementia in the era of highly active antiretroviral therapy (HAART).
Neurological complications associated with HIV-1 are being recognized as a common disorder in AIDS patients, especially patients with HIV-associated dementia (HAD). However, our knowledge of the complicated pathogenesis and clinical symptoms of HAD is limited by an incomplete understanding of the biology of HIV-1 in the nervous system. Therefore, this review focuses on the pathogenesis of HAD in the context of novel highly active antiretroviral therapy (HARRT) regimens.
Pharmacy Department, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Chenglai
C
Xia
Dixian
D
Luo
Xiaoling
X
Yu
Shibo
S
Jiang
Shuwen
S
Liu
D015526:AIDS Dementia Complex / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology*; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans