Recognition characteristics of molecularly imprinted microspheres for triazine herbicides using hydrogen-bond array strategy and their analytical applications for corn and soil samples.
The homogeneous molecularly imprinted microspheres (MIMs) based on a biologically inspired hydrogen-bond array were prepared using allobarbital as the novel functional monomer and divinylbenzene as the cross-linker. The host-guest binding characteristics were examined by molecular simulation and infrared spectroscopy. The resultant MIMs were evaluated using high performance liquid chromatography and solid-phase extraction. The results obtained demonstrate that the good imprinting effect and the excellent selectivity of MIMs are mainly due to the interaction involving the formation of three-point hydrogen bond between host and guest. The complete baseline separation was obtained for five triazine analogues and a metabolite on the MIM HPLC column. The MIMs were further successfully used as a specific sorbent for selective extraction of simetryne from corn and soil samples by molecularly imprinted solid phase extraction. Detection limits and recoveries were 5.8 μg/kg and 0.14 μg/kg and 87.4-105% and 94.6-101% for simetryne in corn and soil sample, respectively.
School of Chemistry & Environment, South China Normal University, Guangzhou 510006, China.
Suqin
S
Wu
Zhiguang
Z
Xu
Qionghui
Q
Yuan
Youwen
Y
Tang
Xiongjun
X
Zuo
Jiaping
J
Lai
D000327:Adsorption; D002851:Chromatography, High Pressure Liquid; D006540:Herbicides / Q000032:analysis* / Q000737:chemistry; D006860:Hydrogen Bonding; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D008958:Models, Molecular; D054802:Molecular Imprinting / Q000379:methods*; D009584:Nitrogen; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D012987:Soil / Q000737:chemistry*; D052616:Solid Phase Extraction; D013055:Spectrophotometry, Infrared; D014227:Triazines / Q000032:analysis* / Q000737:chemistry; D003313:Zea mays / Q000737:chemistry*
D006540:Herbicides; D012987:Soil; D014227:Triazines; C033807:simetryn; D009584:Nitrogen