Diverse strategies toward indenol and fulvene derivatives: Rh-catalyzed C-H activation of aryl ketones followed by coupling with internal alkynes.
The synthesis of indenols and fulvenes was achieved through Rh-catalyzed C-H bond activation of simple and diverse aryl ketone derivatives and subsequent coupling with internal alkynes. The process was found to involve either an α or γ dehydration step, depending on the substrate disposition and representing diverse pathways toward functionalized fulvenes.
Organisch-Chemisches Institut der Westfälischen Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany.
Frederic W
FW
Patureau
Tatiana
T
Besset
Nadine
N
Kuhl
Frank
F
Glorius
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003517:Cyclopentanes / Q000737:chemistry*; D007192:Indenes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
D000480:Alkynes; D003517:Cyclopentanes; D007192:Indenes; D007659:Ketones; C017332:fulvene; C093580:1-indenol; D012238:Rhodium