Comparison of anterior segment measurements with rotating Scheimpflug photography and partial coherence reflectometry.
OBJECTIVE
To compare central corneal thickness (CCT), anterior chamber depth (ACD), and keratometry (K) readings measured using optical low-coherence reflectometry (OLCR) biometry and high-resolution rotating Scheimpflug photography.


METHODS
Eye Hospital of Wenzhou Medical College, Wenzhou, China.


METHODS
Comparative case series.


METHODS
The CCT, ACD endothelium to lens, ACD epithelium to lens, and K (mean; in flattest meridian; in steepest meridian) were measured 5 times using the LenStar/Biograph OLCR biometer and 3 times with the Pentacam Scheimpflug system in eyes of healthy volunteers. Concordance was evaluated using paired t tests, the Pearson correlation, and Bland-Altman analyses.


RESULTS
The CCT, ACD endothelium to lens, and ACD epithelium to lens measured with the Scheimpflug system were slightly, albeit significantly, higher than with the OLCR biometer (P<.05); the respective 95% limits of agreement (LoA) were -8.2 μm to 15.7 μm, -0.11 to 0.15 mm, and -0.13 to 0.17 mm. However, the Scheimpflug system gave significantly flatter readings for K in the flattest meridian (95% LoA, -0.54 to 0.32 diopters [D]), K in the steepest meridian (95% LoA, -0.63 to 0.45 D), and mean K (95% LoA, -0.53 to 0.33 D) (P<.001). The CCT, ACD, and K readings were all highly correlated between the 2 devices (r >0.95, P<.001).


CONCLUSIONS
The CCT and ACD measurements with the OLCR biometer and Scheimpflug system can be used interchangeably in healthy young subjects. However, for K measurements, these devices have wide LoA so may not be interchangeable under certain clinical circumstances.
Key Laboratory of Vision Science, School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical College, Ministry of Health PR China.
Jinhai
J
Huang
Konrad
K
Pesudovs
Daizong
D
Wen
Shihao
S
Chen
Thomas
T
Wright
Xiaoyu
X
Wang
Yini
Y
Li
Qinmei
Q
Wang
D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000033:anatomy & histology*; D001699:Biometry; D003315:Cornea / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology*; D008297:Male; D010781:Photography / Q000379:methods*; D012399:Rotation; D055815:Young Adult