Pregnancy and commonly used drugs in hematology practice.
When a woman suffering from a hematological condition is contemplating pregnancy, she may need to continue the use of medications that do not have sufficient evidence of fetal safety. We discuss the evidence existing for some therapies of major hematological conditions in the context of major principles in clinical teratology. It is critical to always balance the potential fetal risks of the drug in question against the maternal and fetal risks of the untreated hematological condition.
Motherisk Program, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada. gkoren@sickkids.ca
Gideon
G
Koren
Michael
M
Lishner
D005260:Female; D005333:Fetus; D006401:Hematologic Agents / Q000009:adverse effects / Q000145:classification / Q000627:therapeutic use*; D019337:Hematologic Neoplasms / Q000150:complications / Q000188:drug therapy; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011364:Professional Practice
D006401:Hematologic Agents