Acute strength exercise and the involvement of small or large muscle mass on plasma brain-derived neurotrophic factor levels.
OBJECTIVE
Blood neurotrophins, such as the brain-derived neurotrophic factor, are considered to be of great importance in mediating the benefits of physical exercise. In this study, the effect of acute strength exercise and the involvement of small versus large muscle mass on the levels of plasma brain-derived neurotrophic factor were evaluated in healthy individuals.


METHODS
The concentric strengths of knee (large) and elbow (small) flexor and extensor muscles were measured on two separate days. Venous blood samples were obtained from 16 healthy subjects before and after exercise.


RESULTS
The levels of brain-derived neurotrophic factor in the plasma did not significantly increase after both arm and leg exercise. There was no significant difference in the plasma levels of the brain-derived neurotrophic factor in the arms and legs.


CONCLUSIONS
The present results demonstrate that acute strength exercise does not induce significant alterations in the levels of brain-derived neurotrophic factor plasma concentrations in healthy individuals. Considering that its levels may be affected by various factors, such as exercise, these findings suggest that the type of exercise program may be a decisive factor in altering peripheral brain-derived neurotrophic factor.
Departamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, Brazil. paulo@nutriativo.com.br
Paulo Roberto
PR
Correia
Aline
A
Pansani
Felipe
F
Machado
Marilia
M
Andrade
Antonio Carlos da
AC
Silva
Fulvio Alexandre
FA
Scorza
Esper Abrão
EA
Cavalheiro
Ricardo Mario
RM
Arida
D000328:Adult; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood*; D004551:Elbow Joint / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007719:Knee Joint / Q000502:physiology; D008297:Male; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000378:metabolism*; D055070:Resistance Training / Q000379:methods*; D013997:Time Factors; D055815:Young Adult
D019208:Brain-Derived Neurotrophic Factor
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