[Evidence-based antibiotic prophylaxis in general and visceral surgery].
The use of prophylactic perioperative antibiotic therapy if indicated could successfully and safely prevent surgical wound infections. The current guidelines (S1) for prophylactic perioperative antibiotic therapy of the Study Group of the Scientific Medical Associations (AWMF) of 2004 was replaced by a recommendation of the study group of the Paul-Ehrlich-Gesellschaft for Chemotherapy (PEG) in 2010. This recommendation includes recent research data from 2000 to 2008. Indications and choice of antibiotic agent depend on specific risk factors of the patient and the operation performed. The aim of this article is to describe the current recommendations of the PEG for general and visceral surgery.
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany. Phillip.Knebel@med.uni-heidelberg.de
P
P
Knebel
M A
MA
Weigand
M W
MW
Büchler
C M
CM
Seiler
D019072:Antibiotic Prophylaxis; D001062:Appendectomy; D015897:Comorbidity; D003428:Cross Infection / Q000209:etiology / Q000517:prevention & control*; D004066:Digestive System Diseases / Q000601:surgery; D019317:Evidence-Based Medicine; D005858:Germany; D006552:Hernia, Inguinal / Q000601:surgery; D006555:Hernia, Ventral / Q000601:surgery; D006801:Humans; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D012955:Societies, Medical; D013526:Surgical Mesh; D013514:Surgical Procedures, Operative; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control*
Br J Surg. 1989 Jan;76(1):52-6
2645013
Clin Infect Dis. 2004 Jun 15;38(12):1706-15
15227616
J Chemother. 1995 Jul;7 Suppl 3:29-35
8609536
Ann Surg. 2007 Mar;245(3):392-6
17435546
Dtsch Arztebl Int. 2010 Sep;107(37):631-7
20959890
Surg Endosc. 2004 Apr;18(4):638-41
14752639
N Engl J Med. 2006 Dec 21;355(25):2640-51
17182989
J Thorac Cardiovasc Surg. 2008 Dec;136(6):1522-7
19114201
Ann Surg. 2008 Jun;247(6):918-26
18520217
Langenbecks Arch Surg. 2009 Jan;394(1):65-70
18607625
Cochrane Database Syst Rev. 2009 Jan 21;(1):CD001181
19160191
Langenbecks Arch Surg. 2009 Nov;394(6):1011-1017
19730881
Surg Infect (Larchmt). 2002;3 Suppl 1:S9-21
12573036
Eur J Surg. 1997 Mar;163(3):191-8
9085061
J Am Coll Surg. 1997 Apr;184(4):353-6
9100679
Cochrane Database Syst Rev. 2005 Jul 20;(3):CD001439
16034862
Dig Surg. 1999;16(6):512-4
10805552
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2004 Apr;47(4):339-44
15205776
Expert Rev Anti Infect Ther. 2005 Oct;3(5):787-95
16207170
BMC Infect Dis. 2007 Sep 23;7:112
17888179
Surg Clin North Am. 1980 Feb;60(1):27-40
7361226
Int J Colorectal Dis. 2005 Nov;20(6):542-6
15843938
J Thorac Cardiovasc Surg. 2002 Feb;123(2):326-32
11828293
J Hosp Infect. 2000 Oct;46(2):135-40
11049707
Surg Infect (Larchmt). 2008 Dec;9(6):579-84
19216670
Infect Control Hosp Epidemiol. 2008 Jan;29(1):92-4; author reply 94-5
18171198
Br J Surg. 1998 Sep;85(9):1232-41
9752867
Am J Infect Control. 2005 Jun;33(5):292-8
15947746
Cochrane Database Syst Rev. 2009 Jan 21;(1):CD001544
19160198
Ann Thorac Surg. 2007 Nov;84(5):1605-10
17954069
N Engl J Med. 1992 Jan 30;326(5):281-6
1728731
J Formos Med Assoc. 2004 Aug;103(8):607-12
15340659
Lancet. 2008 Mar 8;371(9615):791-3
18328911
Arch Surg. 1999 Jun;134(6):611-3; discussion 614
10367869
Ann Surg. 2009 Apr;249(4):576-82
19300233
Antimicrob Agents Chemother. 2002 Sep;46(9):3026-30
12183263
J Burn Care Res. 2008 Nov-Dec;29(6):917-23
18849849