[The role of seasonal circadian rhythms in hemodynamic regulation].
The review analyzes the possible role of multioscillatory circadian system in the seasonal circadian variability of basic indices of cardiovascular system and probable mechanisms of development of changes in diurnal rhythms of the organism. It was postulated the close relationship between hemodynamic parameters and homeostatic mechanisms of circulation. The destruction of relationship may initiate the development of pathologic condition - desynchronizes. Studies suggest a potential role of relationship between circadian rhythms and secretion of vasoactive peptides, such as angiotensine, endothelins, sodium uretic peptide, endothelial relaxing factor and enkephalins, the circadian rhythmicity of receptor. It is suggested the necessity of investigation of circadian hemodynamic rhythms during desinchronoses formation in purpose of rational pharmacotherapy of different cardiovascular diseases.
N
N
Gongadze
L
L
Gabunia
K
K
Bakuridze
D
D
Abulashvili
T
T
Makharadze
D000818:Animals; D021081:Chronobiology Disorders / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D020098:Natriuretic Peptide, C-Type / Q000378:metabolism; D018847:Opioid Peptides / Q000378:metabolism; D051381:Rats; D012621:Seasons
D018847:Opioid Peptides; D020098:Natriuretic Peptide, C-Type