Glucural (amigluracyl) improves survival of isolated rat hepatocytes in suspension.
Nonsteroid anti-inflammatory drug glucural (water-soluble N-methyl-D-glucosamine complex with 6-methyluracyl) improves survival of isolated rat hepatocytes stored in suspension. This effect of glucural is presumably explained by its membranotropism.
Institute of Cytology, the Russian Academy of Sciences, St. Petersburg, Russia. sakuta@yandex.ru
G A
GA
Sakuta
E V
EV
Baidyuk
M V
MV
Dobrogorskaya
A P
AP
Shiryaeva
A Ya
AY
Oksman
V I
VI
Morozov
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D019610:Cytoprotection / Q000187:drug effects* / Q000502:physiology; D022781:Hepatocytes / Q000187:drug effects* / Q000502:physiology*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D014498:Uracil / Q000031:analogs & derivatives* / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; C014314:amigluracil; D014498:Uracil