[Progress of relationship between biofilm and prosthetic joint infection].
OBJECTIVE
To summarize the effect of biofilm (BF) on the occurrence of prosthetic joint infection (PJI).


METHODS
The domestic and abroad original literature in recent years about the relationship between BF and PJI was reviewed.


RESULTS
Infection is a critical complication for prosthetic joint replacement. Basic research shows one of the reasons for PJI is BF. After adherence of the bacteria to the surface of prosthetic joint, BF forms through a series of regulation and control system. And it lead to the occurrence of PJI. Recently a lot of progress have been made in the research fields of BF related PJI, which have covered aetiology, diagnosis, treatment, and prevention. Different studies show that BF has close relationship with PJI.


CONCLUSIONS
BF is proved to have close relationship with PJI. It is important on clinical significances to diagnose, treat, and prevent PJI.
Department of Orthopaedics, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, PR China.
Yanjie
Y
Mao
Hao
H
Shen
Yao
Y
Jiang
D018441:Biofilms; D006801:Humans; D007595:Joint Prosthesis / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000382:microbiology*