[Immune thrombocytopenic purpura associated to hepatitis C virus infection: report of one case].
Hepatitis C Virus (HCV) is a cause of secondary chronic immune thrombocytopenic purpura (ITP). We report a 43 year old man with mild Hemophilia A, who received blood transfusions during childhood, that consulted for epistaxis and ecchymoses. The laboratory showed a platelet count of 23.000/mm³, positive HCV serology and elevated transaminases. Steroids administered in pulses followed by oral doses resulted in a partial response requiring a second pulse and association of azathioprine. A steroidal diabetes appeared. Given his refractoriness, splenectomy and liver biopsy were performed. He continued on azathioprine maintaining a platelet count near 50.000/mm³ but continued with bleeding episodes. Liver biopsy showed a chronic active hepatitis.
Unidad de Hematología, Instituto de Medicina, Universidad Austral de Chile, Chile. lpilleux@surnet.cl
Lilian
L
Pilleux C
Alejandra
A
Martínez G
Mario
M
Donoso S
Cristian
C
Carrasco L
D000328:Adult; D006467:Hemophilia A / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008297:Male; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000821:virology*; D019562:Viral Load