Dexmedetomidine as an adjuvant analgesic for intractable cancer pain.
Abstract Dexmedetomidine (Precedex®) is an alpha-2 adrenergic agonist that can produce sedation and analgesia without causing respiratory depression. Its use has been described in patients undergoing mechanical ventilation, sedation for surgical and nonsurgical procedures, and prevention of withdrawal. We describe its use as an adjuvant analgesic in a patient with cancer pain refractory to multiple treatment modalities.
Massey Cancer Center, Virginia Commonwealth University , Richmond, VA 23298-0230, USA.
Seth B
SB
Roberts
Colin P
CP
Wozencraft
Patrick J
PJ
Coyne
Thomas J
TJ
Smith
D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology*; D010148:Intractable Pain / Q000188:drug therapy*
D018712:Analgesics, Non-Narcotic; D020927:Dexmedetomidine