DESIGN AND PRELIMINARY VALIDATION OF A RAPID AUTOMATED BIODOSIMETRY TOOL FOR HIGH THROUGPUT RADIOLOGICAL TRIAGE.
This paper presents design, hardware, software, and parameter optimization for a novel robotic automation system. RABiT is a Rapid Automated Biodosimetry Tool for high throughput radiological triage. The design considerations guiding the hardware and software architecture are presented with focus on methods of communication, ease of implementation, and need for real-time control versus soft time control cycles. The design and parameter determination for a non-contact PVC capillary laser cutting system is presented. A novel approach for lymphocyte concentration estimation based on computer vision is reported. Experimental evaluations of the system components validate the success of our prototype system in achieving a throughput of 6,000 samples in a period of 18 hours.
Department of Mechanical Engineering Advanced Robotics and Mechanism Applications Research Laboratory, Columbia University, New York, NY 10027, U.S.A.
Youhua
Y
Chen
Jian
J
Zhang
Hongliang
H
Wang
Guy
G
Garty
Yanping
Y
Xu
Oleksandra V
OV
Lyulko
Helen C
HC
Turner
Gerhard
G
Randers-Pehrson
Nabil
N
Simaan
Y Lawrence
YL
Yao
D J
DJ
Brenner
Mutat Res. 2003 Jan 10;534(1-2):65-75
12504755
Methods Enzymol. 2006;409:236-50
16793405
BMC Biotechnol. 2006 Feb 16;6:9
16483377
Radiat Res. 2005 Jan;163(1):115-23
15606315
Bioinformatics. 2006 Jul 15;22(14):e464-71
16873508