A case of Behçet's disease complicated by bilateral posterior ischemic optic neuropathy.
We report a case involving bilateral posterior ischemic optic neuropathy with Behçet's disease in a 49-year-old woman. The patient presented because of abrupt visual disturbances. An ophthalmic examination, including fluorescein angiography, visual field testing, and visual-evoked potentials, was performed. Her visual acuity was 20/100 bilaterally and posterior ischemic optic neuropathy was suspected. She was treated with systemic methylprednisolone; however, disc pallor developed and the visual acuity remained 20/200 bilaterally. Optic neuropathy can be bilateral, affect both eyes simultaneously, and lead to severe visual loss despite high doses of systemic steroid treatment. Optic neuropathy in Behçet's disease is very rare. This case provides clinical insight into the neuro-ophthalmologic manifestations of Behçet's disease.
Department of Ophthalmology, Hallym University Sacred Heart Hospital, Chuncheon-si, Republic of Korea. jiwoneye@hallym.or.kr
Ji Won
JW
Lim
Shin Hee
SH
Kang
D000284:Administration, Oral; D001528:Behcet Syndrome / Q000150:complications*; D005074:Evoked Potentials, Visual; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000008:administration & dosage; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology; D014792:Visual Acuity; D058609:Visual Field Tests
D005938:Glucocorticoids; D011239:Prednisolone; D008775:Methylprednisolone
Eur J Ophthalmol. 2002 Sep-Oct;12(5):424-31
12474927
Mod Rheumatol. 2009;19(3):334-7
19319466
Ophthalmologica. 2006;220(6):400-5
17095888
Prog Retin Eye Res. 2009 Jan;28(1):34-62
19063989
J Dtsch Dermatol Ges. 2007 Nov;5(11):1010-4
17976143
J Clin Neuroophthalmol. 1989 Dec;9(4):277-80
2531168