The influence of emotion regulation on decision-making under risk.
Cognitive strategies typically involved in regulating negative emotions have recently been shown to also be effective with positive emotions associated with monetary rewards. However, it is less clear how these strategies influence behavior, such as preferences expressed during decision-making under risk, and the underlying neural circuitry. That is, can the effective use of emotion regulation strategies during presentation of a reward-conditioned stimulus influence decision-making under risk and neural structures involved in reward processing such as the striatum? To investigate this question, we asked participants to engage in imagery-focused regulation strategies during the presentation of a cue that preceded a financial decision-making phase. During the decision phase, participants then made a choice between a risky and a safe monetary lottery. Participants who successfully used cognitive regulation, as assessed by subjective ratings about perceived success and facility in implementation of strategies, made fewer risky choices in comparison with trials where decisions were made in the absence of cognitive regulation. Additionally, BOLD responses in the striatum were attenuated during decision-making as a function of successful emotion regulation. These findings suggest that exerting cognitive control over emotional responses can modulate neural responses associated with reward processing (e.g., striatum) and promote more goal-directed decision-making (e.g., less risky choices), illustrating the potential importance of cognitive strategies in curbing risk-seeking behaviors before they become maladaptive (e.g., substance abuse).
Department of Psychology, RutgersUniversity, 101Warren Street, Newark, NJ 07102, USA. delgado@psychology.rutgers.edu
Laura N
LN
Martin
Mauricio R
MR
Delgado
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D003657:Decision Making / Q000502:physiology*; D004644:Emotions; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007206:Individuality; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D011930:Reaction Time / Q000502:physiology; D012309:Risk-Taking; D055815:Young Adult
D010100:Oxygen
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1249-54
19164587
J Cogn Neurosci. 2002 Nov 15;14(8):1215-29
12495527
Neuroimage. 2002 Apr;15(4):870-8
11906227
Biol Psychiatry. 2005 Feb 1;57(3):210-9
15691521
Neuron. 2005 Sep 1;47(5):763-70
16129404
J Cogn Neurosci. 2006 Aug;18(8):1266-76
16859413
Science. 2007 Jan 26;315(5811):515-8
17255512
Curr Opin Pharmacol. 2005 Feb;5(1):9-19
15661620
Acad Manage J. 2007 Aug;50(4):923-940
18449361
Nat Neurosci. 2008 Aug;11(8):880-1
18587392
Trends Cogn Sci. 2006 Apr;10(4):182-91
16530463
J Neurosci. 2007 Nov 21;27(47):12860-7
18032658
Neuroimage. 2009 Aug 15;47(2):713-21
19442745
J Cogn Neurosci. 2010 Feb;22(2):248-62
19400679
J Neurosci. 2006 Sep 13;26(37):9530-7
16971537
J Neurosci. 2006 Apr 5;26(14):3805-12
16597734
J Neurosci. 2007 Aug 1;27(31):8161-5
17670959
Psychopharmacology (Berl). 2005 Dec;183(2):171-80
16163517
Cereb Cortex. 2002 Sep;12(9):926-35
12183392
Neuropsychopharmacology. 2010 Jan;35(1):4-26
19812543
Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3125-35
18640910
Neuroimage. 2006 Nov 1;33(2):725-31
16959497
J Cogn Neurosci. 2007 May;19(5):776-98
17488204
Curr Opin Neurobiol. 2004 Dec;14(6):769-76
15582382
Neuroreport. 2004 Sep 15;15(13):2123-7
15486494
Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5035-40
19289824
Brain Res. 2009 Sep 22;1290:28-51
19576868
J Gambl Stud. 2007 Jun;23(2):121-32
17245663
Drug Alcohol Depend. 2010 Jan 1;106(1):52-5
19748191
Trends Cogn Sci. 2005 May;9(5):242-9
15866151
Neuroscience. 2009 Nov 24;164(1):43-54
19559759
Cogn Affect Behav Neurosci. 2005 Jun;5(2):156-68
16180622
Curr Dir Psychol Sci. 2008 Apr;17(2):153-158
25425765
J Neurosci. 2009 Oct 7;29(40):12574-83
19812332
Hum Brain Mapp. 2007 May;28(5):409-23
17133391
Neuroimage. 2006 Jun;31(2):790-5
16487726
Brain. 2008 May;131(Pt 5):1311-22
18390562
Soc Cogn Affect Neurosci. 2010 Dec;5(4):369-77
20147457
Science. 2009 May 1;324(5927):646-8
19407204
J Neurosci. 2008 Mar 12;28(11):2745-52
18337404
Biol Psychiatry. 2009 Mar 1;65(5):367-73
18930182
Trends Neurosci. 1990 Jul;13(7):266-71
1695401
Nat Rev Neurosci. 2008 Jul;9(7):545-56
18545266
Neuropsychopharmacology. 2010 Jan;35(1):48-69
19776734
Neuroimage. 2004 Oct;23(2):483-99
15488398
J Neurosci. 2009 Feb 18;29(7):2231-7
19228976
Ann N Y Acad Sci. 2007 May;1104:70-88
17344522
Acta Neuropsychiatr. 2006 Jun;18(3-4):144-53
26989966
Neuroimage. 2010 Feb 1;49(3):2536-43
19913102
J Pers Soc Psychol. 2003 Aug;85(2):348-62
12916575
Neuron. 2008 Sep 11;59(5):829-38
18786365
J Pers. 2004 Dec;72(6):1301-33
15509284
Neuroimage. 2007 Nov 15;38(3):557-63
17889562
Curr Opin Neurol. 2005 Aug;18(4):411-7
16003117