Palladium-catalyzed carboiodination of alkenes: carbon-carbon bond formation with retention of reactive functionality.
We report a palladium-catalyzed carbon-carbon bond-forming reaction between aryl iodides and alkenes. In contrast to traditional cross-coupling reactions, two new bonds are formed, and all of the atoms in the starting materials are incorporated into the product. The use of a palladium catalyst with bulky phosphine ligands is found to be crucial for reactivity.
Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada M5S 3H6.
Stephen G
SG
Newman
Mark
M
Lautens
D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D054879:Halogenation; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
D000475:Alkenes; D010165:Palladium; D002244:Carbon