Persistent infection or successive reinfection of deer mice with Bartonella vinsonii subsp. arupensis.
Bartonella infections are common in rodents. From 1994 to 2006, longitudinal studies of a rodent community, consisting mainly of deer mice (Peromyscus maniculatus), were conducted in southwestern Colorado to study hantaviruses. Blood samples from deer mice captured one or more times during the period 2003 to 2006 (n = 737) were selected to study bartonellae in deer mice. Bartonellae were found to be widely distributed in that population, with an overall prevalence of 82.4% (607/737 mice). No correlation was found between bartonella prevalence and deer mouse weight or sex. Persistent or successive infections with bartonellae were observed in deer mice captured repeatedly, with a prevalence of 83.9% (297/354), and the infection appeared to last for more than 1 year in some of them. Persistent infection with bartonellae may explain the high prevalence of these bacteria in deer mice at this site and, perhaps, elsewhere. Genetic analysis demonstrated that deer mouse-borne bartonella isolates at this site belong to the same species, B. vinsonii subsp. arupensis, demonstrating a specific relationship between B. vinsonii subsp. arupensis and deer mice.
Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA. YBai1@cdc.gov
Ying
Y
Bai
Charles H
CH
Calisher
Michael Y
MY
Kosoy
J Jeffrey
JJ
Root
Jeffrey B
JB
Doty
D000818:Animals; D001473:Bartonella / Q000302:isolation & purification*; D001474:Bartonella Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D001769:Blood / Q000382:microbiology; D003120:Colorado / Q000453:epidemiology; D008137:Longitudinal Studies; D010542:Peromyscus / Q000382:microbiology*; D015995:Prevalence; D012376:Rodent Diseases / Q000453:epidemiology* / Q000382:microbiology*
J Clin Microbiol. 2005 Feb;43(2):945-7
15695714
Int J Syst Evol Microbiol. 2004 Nov;54(Pt 6):1959-1967
15545418
Ann Trop Med Parasitol. 1994 Jun;88(3):317-27
7944677
Ecology. 2007 Jul;88(7):1841-9
17645030
Emerg Infect Dis. 2004 Apr;10(4):684-7
15200860
Am J Trop Med Hyg. 2004 Apr;70(4):429-33
15100459
Clin Microbiol Infect. 2009 Dec;15 Suppl 2:102-3
19929978
Int J Syst Evol Microbiol. 2009 Dec;59(Pt 12):2956-61
19628592
J Clin Microbiol. 2003 Feb;41(2):645-50
12574261
J Clin Microbiol. 1999 Mar;37(3):596-9
9986818
Vector Borne Zoonotic Dis. 2006 Winter;6(4):395-403
17187575
J Clin Microbiol. 1999 Dec;37(12):4034-8
10565926
J Med Entomol. 1996 May;33(3):490-5
8667399
Epidemiol Infect. 2001 Apr;126(2):323-9
11349984
J Clin Microbiol. 1996 Aug;34(8):1952-6
8818889
Ann Trop Med Parasitol. 2000 Jan;94(1):55-68
10723524
Am J Trop Med Hyg. 1997 Nov;57(5):578-88
9392599
Vector Borne Zoonotic Dis. 2005 Winter;5(4):402-9
16417436
Am J Clin Pathol. 1991 Apr;95(4 Suppl 1):S58-66
2008885
J Infect Dis. 1998 Feb;177(2):409-16
9466529
Am J Vet Res. 1997 May;58(5):467-71
9140552
Trends Microbiol. 2003 Jul;11(7):318-21
12875815
J Wildl Dis. 1998 Apr;34(2):305-9
9577777
Vector Borne Zoonotic Dis. 2004 Winter;4(4):285-95
15671735
J Clin Microbiol. 1999 Aug;37(8):2598-601
10405408
J Clin Microbiol. 1993 Apr;31(4):872-81
7681847
Vet Microbiol. 2009 Nov 18;139(3-4):293-7
19595521
Parasitology. 2007 Mar;134(Pt 3):413-25
17096870
Emerg Infect Dis. 1999 Jan-Feb;5(1):126-34
10081680
Microb Ecol. 2008 Aug;56(2):373-82
18176820
Am J Trop Med Hyg. 2002 May;66(5):622-7
12201602
FEMS Microbiol Ecol. 2007 Sep;61(3):438-48
17672850