Synthetic approaches to the 2009 new drugs.
New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 21 NCEs marketed in 2009.
Pfizer Inc., La Jolla, CA 92037, USA. Kevin.k.liu@pfizer.com
Kevin K-C
KK
Liu
Subas M
SM
Sakya
Christopher J
CJ
O'Donnell
Andrew C
AC
Flick
Jin
J
Li
D017277:Drug Approval; D015195:Drug Design; D006801:Humans; D058990:Molecular Targeted Therapy; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*
D004364:Pharmaceutical Preparations