[Biologics. Magic bullets - magic effects - magic costs? New therapeutics and their effects].
Biologics and especially therapeutic monoclonal antibodies have an ever increasing impact in the therapy of inflammatory and malignant diseases. They allow a selective blockade of cytokines, receptors and other molecules. This review summarizes the immunological background, the current state and future trends in the development of these therapeutic agents.
Institut für Immunologie, Universitätsklinikum Jena, Leutragraben 3, 07743 Jena. oliver.frey@mti.uni-jena.de
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D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000627:therapeutic use*; D001688:Biological Products / Q000009:adverse effects* / Q000627:therapeutic use*; D005128:Eye Diseases / Q000188:drug therapy*; D006801:Humans; D009885:Ophthalmology / Q000639:trends*
D000911:Antibodies, Monoclonal; D001688:Biological Products
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