Synthesis of egonol derivatives and their antimicrobial activities.
Eighteen derivatives of egonol (A-R) were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus ATCC 29213, Bacillus subtilis ATCC 6633, Candida albicans ATCC 10231 and Escherichia coli ATCC 8739 microorganisms comparing with egonol. The obtained data reported that compound B exhibited improved activities against all tested bacteria than egonol, others have shown different range of activities.
Chemistry Department, Faculty of Science, Ege University, Bornova, İzmir 35100, Turkey. safiye.emirdag@ege.edu.tr
Safiye
S
Emirdağ-Öztürk
Tamer
T
Karayildirim
Hüseyin
H
Anil
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D052117:Benzodioxoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001572:Benzofurans / Q000032:analysis / Q000138:chemical synthesis*; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012639:Seeds; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship; D032362:Styrax; D013463:Sulfuric Acid Esters / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
C560451:3-(2-(1,3-benzodioxol-5-yl)-7-methoxy-1-benzofuran-5-yl)propyl hydrogen sulfate; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D052117:Benzodioxoles; D001572:Benzofurans; D013463:Sulfuric Acid Esters