Anaphylactic reactions to measles-mumps-rubella vaccine in three children with allergies to hen's egg and cow's milk.
OBJECTIVE
Allergies to hen's egg and cow's milk are the most frequent food allergies in infancy and childhood. Current guidelines recommend safe administration of measles-mumps-rubella (MMR) vaccine in egg allergic patients.


METHODS
We present three cases of anaphylaxis that we encountered after MMR vaccination in children sensitized to hen's egg and cow's milk.


RESULTS
Even though MMR vaccine is generally known to be safe in children with egg allergy, there may still be isolated cases of anaphylaxis.


CONCLUSIONS
Therefore, we recommend that all children not only those who were sensitized to foods should receive the MMR vaccination in a setting that is equipped to deal with anaphylactic reactions. As stated by WHO in immunization safety surveillance, 'Each vaccinator must have an emergency kit with adrenaline, and be familiar with its dosage and administration'.
Pediatric Allergy and Asthma Unit, Hacettepe University, School of Medicine, Ankara, Turkey.
Suleyman Tolga
ST
Yavuz
Umit Murat
UM
Sahiner
Bulent Enis
BE
Sekerel
Ayfer
A
Tuncer
Omer
O
Kalayci
Cansin
C
Sackesen
D000707:Anaphylaxis / Q000175:diagnosis / Q000209:etiology*; D002648:Child; D021181:Egg Hypersensitivity / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000009:adverse effects*; D016269:Milk Hypersensitivity / Q000150:complications*
D022542:Measles-Mumps-Rubella Vaccine