Successful therapeutic hypothermia in patients with congenital long QT syndrome.
Therapeutic hypothermia has been shown to improve neurological outcomes in patients who remain comatose following resuscitation from cardiac arrest. While there are numerous reports of patients who have had a successful course after induction of therapeutic hypothermia, such therapeutic intervention has not been described in patients with congenital long QT syndrome (LQTS). We report outcomes in two patients with LQTS who had therapeutic hypothermia following a ventricular fibrillation arrest. Careful and routine monitoring of the QT interval in this patient population is necessary due to the potential for worsening electrical instability during induced hypothermia.
Department of Cardiovascular Diseases, University of Rochester Medical Center, Strong Memorial Hospital, 601 Elmwood Avenue, Rochester, NY 14642, USA. Mehmet_Aktas@urmc.rochester.edu
Mehmet K
MK
Aktas
Alian
A
Aguila
D000328:Adult; D002648:Child; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008133:Long QT Syndrome / Q000151:congenital / Q000628:therapy*; D008297:Male; D058687:Out-of-Hospital Cardiac Arrest / Q000209:etiology / Q000628:therapy; D011644:Puerperal Disorders / Q000628:therapy; D014693:Ventricular Fibrillation / Q000150:complications
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