Label-free DNAzyme-based fluorescing molecular switch for sensitive and selective detection of lead ions.
We developed a label-free fluorescent Pb(2+) sensor utilizing a DNAzyme-based fluorescing molecular switch, which enables fluorescence detection of Pb(2+) in aqueous solution with high sensitivity and selectivity.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, P. R. China.
Libing
L
Zhang
Bingyan
B
Han
Tao
T
Li
Erkang
E
Wang
D002942:Circular Dichroism; D021881:DNA, Catalytic / Q000737:chemistry* / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D007854:Lead / Q000032:analysis*; D009930:Organic Chemicals / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods*
D021881:DNA, Catalytic; D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; D007477:Ions; D009930:Organic Chemicals; C099476:PicoGreen; D007854:Lead