Leptin role in the rat prostate ventral lobe.
The involvement of leptin in prostate diseases is related to an increase in the gene expression of both a and b isoform leptin receptors, leptin itself, androgen receptor, and aromatase, as well as by a reduction in both estrogen isoform receptors.
Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, Brazil. cristiane@pesquisador.com.br
Sicilia
S
Colli
Fernanda
F
Silveira Cavalcante
Max
M
Peixoto Martins
Francisco Jose
FJ
Sampaio
Cristiane
C
da Fonte Ramos
D000818:Animals; D005786:Gene Expression Regulation / Q000502:physiology; D020738:Leptin / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D008297:Male; D009924:Organ Culture Techniques; D009929:Organ Size; D011467:Prostate / Q000473:pathology / Q000502:physiology*; D020033:Protein Isoforms / Q000096:biosynthesis / Q000502:physiology; D051381:Rats; D054411:Receptors, Leptin / Q000096:biosynthesis / Q000502:physiology*
D020738:Leptin; D020033:Protein Isoforms; D054411:Receptors, Leptin