New strategy to construct fused/bridged/spiro carbocyclic scaffolds based on the design of novel 6-C synthon precursor.
In this article we report a new strategy to build fused/spiro/bridged carbocyclic systems with a novel 6-C synthon from readily available diallyl diacetates through the sequential Pd-catalyzed double allyl alkylation and Diels-Alder annulation. Further exploration on the application of this strategy can construct useful complex scaffolds.
Department of Applied Chemistry, China Agricultural University, Beijing 100193, PR China.
Jia
J
Liu
Xi
X
Wang
Chang-Liang
CL
Sun
Bi-Jie
BJ
Li
Zhang-Jie
ZJ
Shi
Min
M
Wang