Stabilization of vesicular and supported membranes by glycolipid oxime polymers.
We report herein new synthetic glycolipid dimers and polymers that provide unprecedented stability to both supported (SLBs) and vesicular lipid bilayers against dehydration and serum exposure. These novel physical properties will enable pharmaceutical delivery and development of SLB bioanalytical devices.
Department of Chemistry, The Ohio State University, 100 W. 18th Avenue, Columbus, OH 43210, USA.
Mingming
M
Ma
Soumitra
S
Chatterjee
Meng
M
Zhang
Dennis
D
Bong
D000388:Air; D000818:Animals; D002417:Cattle; D019281:Dimerization; D005612:Freeze Drying; D006017:Glycolipids / Q000737:chemistry* / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D010091:Oximes / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D053835:Unilamellar Liposomes / Q000097:blood / Q000737:chemistry*
D006017:Glycolipids; D008051:Lipid Bilayers; D010091:Oximes; D011108:Polymers; D053835:Unilamellar Liposomes