bla(CTX-M)-carrying Escherichia coli of the O25b ST131 clonal group have emerged in China.
Six Escherichia coli O25b ST131 isolates, which were mostly hospital-acquired but from various types of samples, were found to carry bla(CTX-M-3a,)bla(CTX-M-14), or bla(CTX-M-65) genes, demonstrating that such isolates have emerged in China. The bla(CTX-M) genes were mostly carried by IncFII-related conjugative plasmids. All isolates were also resistant to ciprofloxacin and gentamicin and had substitutions in GyrA and carried an aac(3)-II gene.
Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China. zongzhiy@scu.edu.cn
Zhiyong
Z
Zong
Rujia
R
Yu
D015373:Bacterial Typing Techniques; D002681:China; D004926:Escherichia coli / Q000235:genetics* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000235:genetics* / Q000382:microbiology*; D005798:Genes, Bacterial / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D058885:Multilocus Sequence Typing; D019081:O Antigens / Q000235:genetics*; D010957:Plasmids; D001618:beta-Lactamases / Q000235:genetics*
D019081:O Antigens; D001618:beta-Lactamases