Effect of Aike Mixture on the inflammatory infiltration in patients with chronic prostatitis type III A.
OBJECTIVE
To observe the effect of Aike Mixture (AKM) on prostatic inflammatory infiltration in patients with chronic prostatitis type III A (III A-CP/CPPS) and evaluate its anti-inflammatory action. METHODS METHODS: A total of 60 patients with III A-CP/CPPS suitable to operation and differentiated as Chinese medicine: Gan qi stagnancy syndrome type were selected. They were assigned with the random number table to two groups equally. Before operation, the patients in the treated group were administered with Proscar combined with AKM, but those in the control group treated with Proscar only. Suprapubic transvesical prostatectomy was performed two weeks later, and prostatic pathological examination was conducted.


RESULTS
Grading of: inflammatory cell infiltration showed that the mean grade in the treated group was 0.78 ± 0.90 grades, which was significantly lower than that in the control group 1.68 ± 0.87 grades (P<0.05). However, the two groups were not different in the grades of fibroblast proliferation (1.50 ± 0.70 grades vs 1.62 ± 0.87 grades, P>0.05).


CONCLUSIONS
AKM could suppress the inflammatory cell infiltration, be an effective and safe remedy for the treatment of IIIA-CP/CPPS of Gan-qi stagnancy syndrome type, and worthy for spreading in clinical use.
People's Hospital Affiliated to Fujian College of Traditional Chinese Medicine, Fuzhou 350004, China. zmj83@tom.com
Min-Jian
MJ
Zhang
Jian-Fei
JF
Weng
Ya-Lei
YL
Shi
Wan-Jun
WJ
Cheng
Xiao-Jun
XJ
Ruan
Qiu-Yong
QY
Zhang
D000368:Aged; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007249:Inflammation / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011472:Prostatitis / Q000145:classification / Q000188:drug therapy* / Q000473:pathology*
D004365:Drugs, Chinese Herbal; C557891:aike
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