Postoperative complications and survival rates for pancreatic cancer patients.
OBJECTIVE
Surgical resection offers the only potential cure for pancreatic tumor. The goal of the present study is to determine complications associated with pancreatic resection and to describe their influence on the survival rate for pancreatic cancer patients.


METHODS
Between 1996 and 2009, the findings of 125 pancreatic cancer patients were analyzed in a prospective trial at the First Department of Surgery, University Hospital in Košice, Slovakia.


RESULTS
The overall mortality rate and morbidity rate were 3.2% (4 patients) and 27% (34 patients), respectively. In patients with postoperative complications, the median survival time was 12 months (range, 8-14 months), in patients without complications - 18 months (range, 15-20 months).


CONCLUSIONS
The presence of postoperative complications after pancreatic resections has negative influence on the survival rate for pancreatic cancer patients. Patients with a small pancreatic duct size (<3 mm) or a soft pancreatic remnant were at high risk of pancreatic leakage and postoperative complications.
First Department of Surgery, University Hospital Košice, Košice, Slovakia. jana.katuchova@upjs.sk
Jana
J
Kaťuchová
Juray
J
Bober
Jozef
J
Radoňak
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000401:mortality*; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality*; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D018154:Slovakia / Q000453:epidemiology; D016019:Survival Analysis; D015996:Survival Rate
Surgery. 2007 Nov;142(5):761-8
17981197
Arch Surg. 2003 Dec;138(12):1310-4; discussion 1315
14662530
Am J Surg. 1992 Jan;163(1):125-30; discussion 130-1
1733360
J Hepatobiliary Pancreat Surg. 2008;15(3):247-51
18535760
Br J Surg. 1994 Feb;81(2):265-9
8156354
Br J Surg. 2004 Nov;91(11):1410-27
15499648
Surgery. 2005 Jul;138(1):8-13
16003309
Ann Surg. 2004 Dec;240(6):993-1000; discussion 1000-1
15570205
Ann Surg. 2002 Sep;236(3):355-66; discussion 366-8
12192322
World J Gastroenterol. 2006 Jul 28;12(28):4466-72
16874856
Ann Surg. 2005 Dec;242(6):767-71, discussion 771-3
16327486
Clin Gastroenterol Hepatol. 2004 Jun;2(6):510-7
15181621
Ann Surg. 2000 Sep;232(3):419-29
10973392
J Hepatobiliary Pancreat Surg. 2008;15(3):262-9
18535763
Ann Surg. 1995 Oct;222(4):580-8; discussion 588-92
7574936