Differential expression of uncoupling mitochondrial protein and alternative oxidase in the plant response to stress.
Different cell types, organs and tissues shape their mitochondrial proteome according to the cellular environment that is dictated by differentiation, development and metabolic status. Under each circumstance, members of multigenic families that encode mitochondrial proteins are differentially expressed to meet the mitochondrial metabolic demand. However, the mitochondrial proteome may drastically change in response to stress conditions. Examples of the changes in mitochondrial protein expression caused by stress are represented by the energy-dissipating mitochondrial uncoupling protein (UCP) and alternative oxidase (AOx). UCP and AOx belong to multigenic families in plants, and their members, which are expressed in a time/tissue specific manner, respond differentially to stress conditions. In general, UCP and AOx are not expressed at the same levels concurrently in the same tissue, and the level of each protein varies in each stress condition. In addition, under non-stress conditions, UCP is expressed at much higher levels compared with AOx. The role of their differential expression in plant growth, development and response to stress is discussed.
Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
Thais Resende Silva
TR
Figueira
Paulo
P
Arruda
D004734:Energy Metabolism / Q000235:genetics*; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology*; D007473:Ion Channels / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D010940:Plant Proteins; D010944:Plants / Q000378:metabolism*; D013045:Species Specificity; D013312:Stress, Physiological / Q000502:physiology*; D000071256:Uncoupling Protein 1; D000099188:Alternative Oxidase
D007473:Ion Channels; D024101:Mitochondrial Proteins; D010088:Oxidoreductases; D010940:Plant Proteins; D000071256:Uncoupling Protein 1; D000099188:Alternative Oxidase
J Biol Chem. 2003 Jun 20;278(25):22298-302
12672801
Cell Metab. 2009 Oct;10(4):324-35
19808025
Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19587-92
17148605
Biosci Rep. 2001 Apr;21(2):213-22
11725870
J Exp Bot. 2009;60(13):3909-22
19640927
Braz J Med Biol Res. 2000 Mar;33(3):259-68
10719376
J Bioenerg Biomembr. 1999 Oct;31(5):399-406
10653469
J Exp Bot. 2006;57(4):849-64
16473895
Plant Physiol Biochem. 2004 Apr;42(4):283-90
15120112
Nature. 2003 Nov 20;426(6964):243-4
14628037
J Bioenerg Biomembr. 2003 Jun;35(3):203-9
13678271
Biochim Biophys Acta. 2006 May-Jun;1757(5-6):480-5
16597432
Plant Cell Environ. 2008 Aug;31(8):1190-202
18507803
Plant Physiol. 2008 Feb;146(2):636-45
18162588
Plant Mol Biol. 2003 Mar;51(5):745-55
12678560
J Biol Chem. 2004 Dec 10;279(50):51944-52
15456782
Biosci Rep. 2005 Jun-Aug;25(3-4):209-26
16283554