Sirt3 targets mPTP and prevents aging in the heart.
Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, UMDNJ, New Jersey Medical School, Newark, 07103, USA. Sadoshju@umdnj.edu
Junichi
J
Sadoshima
D000375:Aging / Q000502:physiology*; D000818:Animals; D006321:Heart / Q000502:physiology*; D006801:Humans; D008929:Mitochondria, Heart / Q000378:metabolism* / Q000648:ultrastructure; D033681:Mitochondrial Membrane Transport Proteins / Q000378:metabolism*; D056566:Sirtuin 3 / Q000378:metabolism*
D033681:Mitochondrial Membrane Transport Proteins; D056566:Sirtuin 3
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