Copper-free Sonogashira coupling of cyclopropyl iodides with terminal alkynes.
The substrate scope of the copper-free Sonogashira coupling has been successfully extended to cyclopropyl iodides, allowing an efficient access to a wide variety of functionalized alkynyl cyclopropanes.
Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, Paris, France.
Benoît
B
de Carné-Carnavalet
Alexis
A
Archambeau
Christophe
C
Meyer
Janine
J
Cossy
Benoît
B
Folléas
Jean-Louis
JL
Brayer
Jean-Pierre
JP
Demoute
D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry
D000480:Alkynes; D003521:Cyclopropanes; D006847:Hydrocarbons, Iodinated; D010165:Palladium; D003300:Copper