Prospective randomized clinical study of arterial pumps used for routine on pump coronary bypass grafting.
In a number of studies, centrifugal blood pumps--in comparison with roller pumps--have been shown to attenuate trauma to blood components. Nevertheless, the impact of these results on the postoperative course needs to be discussed controversially. In a prospective randomized study, 240 consecutive adult patients underwent elective myocardial revascularization with cardiopulmonary bypass employing five different pumps (Roller, Avecor, Sarns, Rotaflow, Bio-Medicus). We analyzed clinical course, blood loss, damage of blood components, and impairment of the hemostatic system. The study population was homogenous with respect to age, gender, myocardial function, and operative data. No differences were found with respect to time of ventilation, duration of intensive care stay, hospitalization, and laboratory data. The choice of arterial pump during standard extracorporeal bypass for elective coronary artery bypass grafting is no matter of concern.
Department of Cardiothoracic Surgery, University Hospital Regensburg, Germany. andreas.keyser@klinik.uni-regensburg.de
Andreas
A
Keyser
Michael K
MK
Hilker
Claudius
C
Diez
Alois
A
Philipp
Maik
M
Foltan
Christof
C
Schmid
D000368:Aged; D000704:Analysis of Variance; D001663:Bilirubin / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002315:Cardiopulmonary Bypass / Q000009:adverse effects / Q000295:instrumentation*; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000295:instrumentation*; D017558:Elective Surgical Procedures; D004906:Erythrocyte Count; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D005340:Fibrinogen / Q000378:metabolism; D005858:Germany; D006353:Heart-Assist Devices / Q000009:adverse effects; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011183:Postoperative Complications / Q000097:blood / Q000209:etiology; D011446:Prospective Studies; D011474:Prosthesis Design; D013917:Thrombin / Q000378:metabolism; D013997:Time Factors; D016896:Treatment Outcome
D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D006454:Hemoglobins; C036309:fibrin fragment D; D005340:Fibrinogen; D007770:L-Lactate Dehydrogenase; D013917:Thrombin; D001663:Bilirubin