Synergistic toxic effect of nano-TiO and As(V) on Ceriodaphnia dubia.
Due to the active development and application of nanotechnology, engineered nanomaterials (ENMs) are becoming a new class of environmental pollutants that may significantly impact the environment and human health. While many toxicity investigations have been conducted, there is little information about the synergistic effect of ENMs and other toxic compounds in the environment. In order to extend this knowledge, the combined effect of TiO₂ nanoparticles (n-TiO₂) and As(V) were investigated. High concentrations of As(V) can accumulate on the n-TiO₂ surface. Cultured Ceriodaphnia dubia (C. dubia) species were used to examine the synergistic toxic effect through exposure to 1) n-TiO₂ suspensions, 2) As(V) solutions, and 3) mixtures of n-TiO₂ and As(V) suspensions. Results showed that n-TiO₂ alone was not toxic when the concentration was less than 400 mg/L and that the 24-hour median lethal concentration (LC₅₀) of As(V) alone was 3.68±0.22mg/L. However, in the presence of low concentrations of n-TiO₂, the toxicity of As(V) increased significantly. At the same initial As(V) concentration, the toxicity of n-TiO₂ first increased, reached a maximum, and then decreased with an increase in n-TiO₂ concentration. Hydrodynamic size and sorption capacity were most important parameters for toxicity.
Department of Civil, Architectural and Environmental Engineering, Missouri University of Science and Technology, Rolla, MO 65409, USA. wangjia@mst.edu
Demin
D
Wang
Ji
J
Hu
David R
DR
Irons
Jianmin
J
Wang
D000818:Animals; D001151:Arsenic / Q000737:chemistry / Q000633:toxicity*; D003621:Daphnia / Q000187:drug effects*; D004357:Drug Synergism; D053768:Metal Nanoparticles / Q000737:chemistry / Q000633:toxicity*; D014025:Titanium / Q000737:chemistry / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
D014874:Water Pollutants, Chemical; C009495:titanium dioxide; D014025:Titanium; D001151:Arsenic