Copper-mediated intermolecular direct biaryl coupling.
Copper-mediated intermolecular direct biaryl coupling of arylazines and azoles via dual C-H bond cleavage proceeds even without palladium catalysts. The reaction system shows the high potential of copper salts in direct C-H arylation chemistry and provides a new approach to biaryl motifs, which are ubiquitous in pharmaceuticals and functional materials.
Department of Applied Chemistry, Faculty of Engineering, Osaka University , Suita, Osaka 565-0871, Japan.
Masanori
M
Kitahara
Nobuyoshi
N
Umeda
Koji
K
Hirano
Tetsuya
T
Satoh
Masahiro
M
Miura
D001393:Azoles / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D001393:Azoles; D010165:Palladium; D003300:Copper