[The role of hyperbaric oxygenation in combined treatment of acute pyelonephritis].
Hyperbaric oxygenation (HBO) was used in combined treatment of 66 patients with acute pyelonephritis. In 29 of them with primary pyelonephritis it was a part of conservative treatment. In 37 patients with secondary pyelonephritis HBO was applied postoperatively. A HBO course comprised 8-10 sessions under pressure 2.0-2.4 atm for 60 min. It was found that frequency of surgical interventions in HBO administration reduced by 36.2%. Postoperative HBO administration decreased hospital stay by 16.9%. Mechanisms of HBO positive action operate through attenuation of systemic inflammatory reaction and polyorganic insufficiency 1.62 and 2.9-fold, respectively, decline of intoxication in growing glomerular filtration rate and improvement of renal hemodynamics. Moreover, HBO promotes recovery of the immune status. In experiment on 40 white rats with acute pyelonephritis HBO decreased inflammation in renal tissue.
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D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D007249:Inflammation / Q000503:physiopathology / Q000628:therapy; D007668:Kidney / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000503:physiopathology / Q000628:therapy*; D051381:Rats