Effects of dalargin on free radical processes in the blood of rats exposed to moderate hypothermia.
Moderate hypothermia stimulates LPO processes in rat plasma and erythrocytes and simultaneously increases antioxidant activity in the plasma and SOD activity erythrocyte. Dalargin prevents stimulation of LPO in the blood in hypothermia by reducing the generation of active oxygen species and maintaining the level of low-molecular antioxidants.
Department of Biochemistry and Biophysics, Dagestan State University, Makhachkala, Russia.
L T
LT
Tadzhibova
M D
MD
Astaeva
J G
JG
Ismailova
T N
TN
Daudova
N K
NK
Klichkhanov
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001831:Body Temperature; D002374:Catalase / Q000378:metabolism; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D005609:Free Radicals / Q000097:blood*; D007035:Hypothermia / Q000097:blood*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism; D014527:Uric Acid / Q000097:blood
D000975:Antioxidants; D005609:Free Radicals; D014527:Uric Acid; D016308:Enkephalin, Leucine-2-Alanine; D002374:Catalase; D013482:Superoxide Dismutase; C040996:enkephalin-Leu, Ala(2)-Arg(6)-