Supporting adaptive clinical treatment processes through recommendations.
OBJECTIVE
Efficient clinical treatment processes is considered a key factor of medical quality control. Current IT solutions are far away from this perspective since they typically have difficulty supporting the variances occurring in clinical practices, and providing adequate flexible support of clinical processes.


METHODS
This paper proposes a hybrid approach based on rough set theory and case-based reasoning to allow physicians to rapidly adjust patients' treatment processes to changes of patients' clinical states. In detail, the proposed approach recommends appropriate treatment plans in clinical process execution by adopting a similarity measure to select appropriate clinical treatment plans executed on patients who presented similar features to the current one. Such clinical treatment plans are then applied to suggest which actions to perform next in clinical treatment process execution.


RESULTS
As a motivating scenario, this study performs the experiments of type 2 diabetes patient's treatment process. The results show that the proposed approach is feasible to recommend suitable clinical treatment plans in clinical process execution, which makes adaptive clinical treatment processes possible.
College of Biomedical Engineering and Instrument Science of Zhejiang University, The Key Laboratory of Biomedical Engineering, Ministry of Education, China
Xudong
X
Lu
Zhengxing
Z
Huang
Huilong
H
Duan
D000328:Adult; D000368:Aged; D000465:Algorithms; D001786:Blood Glucose / Q000378:metabolism; D003198:Computer Simulation; D020000:Decision Support Systems, Clinical; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008490:Medical Informatics / Q000379:methods*; D008875:Middle Aged; D016730:Program Development; D011786:Quality Control; D012984:Software
D001786:Blood Glucose