Perinatal tuberculosis: two unusual cases.
Two immunocompromised infants with perinatal tuberculosis are reported. Both presented with bilateral miliary mottling of the lungs. The first was a 4-month-old boy with a history of prolonged administration of prednisolone. He had tuberculous meningitis. Diagnosis was confirmed by PCR in serum and CSF. His mother had tuberculous endometritis. The second was a 1-month-old boy with perinatal HIV infection. Diagnosis was made by PCR in serum. Both parents were HIV-infected and had open pulmonary tuberculosis.
Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. drsriparnabasu@rediffmail.com
S
S
Basu
A
A
Kumar
B K
BK
Das
D019380:Anti-HIV Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D000962:Antimalarials / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004716:Endometritis / Q000382:microbiology; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D019829:Nevirapine / Q000627:therapeutic use; D011239:Prednisolone / Q000009:adverse effects; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D011859:Radiography; D014390:Tuberculosis, Meningeal / Q000175:diagnosis* / Q000188:drug therapy; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D015215:Zidovudine / Q000627:therapeutic use
D019380:Anti-HIV Agents; D000893:Anti-Inflammatory Agents; D000962:Antimalarials; D015215:Zidovudine; D019829:Nevirapine; D011239:Prednisolone