The role of Th17 lymphocytes in the autoimmune and chronic inflammatory diseases.
The emerging role of interleukin-17 as a hallmark proinflammatory cytokine of the adaptive immune system produced by a new T helper cell subset termed "Th17" has received considerable attention. In this review we will focus on recent information regarding IL-17 and its relevance in autoimmune and chronic inflammatory diseases.
Department of Internal Medicine, DIMI, University of Genoa, Viale Benedetto XV, n. 6, 16132 Genoa, Italy. Giuseppe.Murdaca@unige.it
Giuseppe
G
Murdaca
Barbara Maria
BM
Colombo
Francesco
F
Puppo
D001172:Arthritis, Rheumatoid / Q000378:metabolism; D001249:Asthma / Q000378:metabolism; D015551:Autoimmunity; D002908:Chronic Disease; D003424:Crohn Disease / Q000378:metabolism; D006801:Humans; D020381:Interleukin-17 / Q000276:immunology*; D008180:Lupus Erythematosus, Systemic / Q000378:metabolism; D009103:Multiple Sclerosis / Q000378:metabolism; D011565:Psoriasis / Q000378:metabolism; D006255:Rhinitis, Allergic, Seasonal / Q000378:metabolism; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
D020381:Interleukin-17
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