Haematological side effect of Helicobacter pylori eradication.
The effect of Helicobacter pylori infection on systemic disorders is not well understood. This study was to evaluate the effect of H. pylori eradication on blood count, differential leucocytic count and RBCs indices. In this study, a total of 115 H. pylori positive patients underwent eradication triple therapy for one week, with cured 100 patients. Complete blood count, RBCs indices and differential leucocytic count were analyzed before 2 & 12 weeks after eradication for the cured patients. The results showed that two weeks after H. pylori eradication, platelets count significantly increased but total leucocytic counts and neutrophils were significantly reduced. After three months, RBCs count, Hb concentration, MCV and MCHC were significantly increased, but lymphocytic counts was significantly reduced.
Department of Tropical Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohamed A
MA
Allam
Abdou M
AM
El-Shafie
A Mohamed
AM
Elwan
Gamal M M
GM
Soliman
Atef
A
Abu-Alfotuh
Hesham
H
Al Shabrawi
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D017291:Clarithromycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology; D016480:Helicobacter pylori; D006402:Hematologic Diseases / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D009853:Omeprazole / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D008795:Metronidazole; D017291:Clarithromycin; D009853:Omeprazole