Outcome of urinary tract infections caused by extended spectrum β-lactamase-producing Enterobacteriaceae in children.
The outcome of patients with urinary tract infections caused by extended spectrum β-lactamases (ESBL)-producing bacteria (cases) was compared with that of matched controls with urinary tract infections caused by non-extended spectrum β-lactamases-producing isolates. Significantly, more case patients received inappropriate empiric therapy than controls. Nevertheless, clinical and microbiologic outcomes as well as formation of renal scars did not differ between the 2 groups.
3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Athanasios
A
Tratselas
Elias
E
Iosifidis
Maria
M
Ioannidou
Stamatis
S
Saoulidis
Konstantinos
K
Kollios
Charalampos
C
Antachopoulos
Danai
D
Sofianou
Emmanuel J
EJ
Roilides
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000494:pharmacology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases