Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women.
OBJECTIVE
To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women.


METHODS
Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 12-16 weeks postpartum.


RESULTS
There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 12-14 weeks postpartum.
2nd Department of Obstetrics and Gynecology, School of Medicine, University of Athens, Aretaieion Hospital, Athens, Greece.
Nicolaos
N
Vitoratos
Nikos F
NF
Vlahos
Emanuel
E
Economou
Konstatninos
K
Panoulis
George
G
Creatsas
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D049590:Postpartum Period / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D013879:Thioredoxins / Q000097:blood*
D013879:Thioredoxins