Reaction screening using a microreactor.
This article discusses the screening of chemical reactions using a microreactor equipped with infrared spectroscopy as online analytics. An esterification reaction has been optimized in continuous mode with the proposed setup. The esterification did not work well due to the material of the microreactor (stainless-steel 316Ti) that catalyzed the decomposition of formic acid. However, despite the occurrence of decomposition, an optimization could be achieved with this system.
Ecole d'ingénieurs et d'architectes de Fribourg, Boulevard de Pérolles 80, CP 32, CH-1705 Fribourg. olivier.naef@hefr.ch
Olivier
O
Naef
Mathieu
M
Roch
Thierry
T
Chappuis
D002384:Catalysis; D002621:Chemistry / Q000379:methods*; D004952:Esters / Q000737:chemistry; D005561:Formates; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D012044:Regression Analysis; D013055:Spectrophotometry, Infrared / Q000379:methods; D013193:Stainless Steel; D013997:Time Factors
D004952:Esters; D005561:Formates; C030544:formic acid; D013193:Stainless Steel