Accurate analysis of trace pentachlorophenol in textiles by isotope dilution liquid chromatography-mass spectrometry.
A highly accurate method for measuring pentachlorophenol (PCP) concentrations in textile samples was developed. This highly accurate method for the analysis of textile samples is valuable, given the inherent challenges associated with the complexity of the sample matrix. This method can be applied to certify the concentration of pentachlorophenol in textile CRMs. A measurement procedure based on isotope dilution liquid chromatography-isotope dilution mass spectrometry (LC-IDMS) was developed. Samples were pretreated with acid and then with n-hexane. Excellent precision was obtained. The validated concentration ranges for the method were 1.0-50 ng/g, the LOD was 1.0 ng/g, and the LOQ was 5.0 ng/g. The precision of this method is in the range of 0.80-1.40%. The method can trace to mass.
Division of Chemical Metrology and Analytical Science, National Institute of Metrology of China, Beijing, PR China. sufh@nim.ac.cn
FuHai
F
Su
Pan
P
Zhang
D002247:Carbon Isotopes / Q000737:chemistry; D002853:Chromatography, Liquid / Q000379:methods* / Q000592:standards; D007201:Indicator Dilution Techniques; D013058:Mass Spectrometry / Q000379:methods* / Q000592:standards; D010416:Pentachlorophenol / Q000032:analysis*; D012015:Reference Standards; D013784:Textiles / Q000032:analysis*
D002247:Carbon Isotopes; D010416:Pentachlorophenol