Artificial neural network for normal, hypertensive, and preeclamptic pregnancy classification using maternal heart rate variability indexes.
OBJECTIVE
A model construction for classification of women with normal, hypertensive and preeclamptic pregnancy in different gestational ages using maternal heart rate variability (HRV) indexes.


METHODS
In the present work, we applied the artificial neural network for the classification problem, using the signal composed by the time intervals between consecutive RR peaks (RR) (n = 568) obtained from ECG records. Beside the HRV indexes, we also considered other factors like maternal history and blood pressure measurements.


CONCLUSIONS
The obtained result reveals sensitivity for preeclampsia around 80% that increases for hypertensive and normal pregnancy groups. On the other hand, specificity is around 85-90%. These results indicate that the combination of HRV indexes with artificial neural networks (ANN) could be helpful for pregnancy study and characterization.
Biochemistry Department, Pharmacy Faculty Porto University, Portugal.
Eduardo
E
Tejera
Maria
M
Jose Areias
Ana
A
Rodrigues
Ana
A
Ramõa
Jose
J
Manuel Nieto-Villar
Irene
I
Rebelo
D000293:Adolescent; D000328:Adult; D001185:Artificial Intelligence; D002965:Classification / Q000379:methods; D003198:Computer Simulation; D004562:Electrocardiography; D005260:Female; D006305:Health Status Indicators; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D007206:Individuality; D016571:Neural Networks, Computer; D015588:Observer Variation; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy / Q000502:physiology*; D011249:Pregnancy Complications, Cardiovascular / Q000145:classification / Q000175:diagnosis; D055815:Young Adult