Zn2+-triggered excited-state intramolecular proton transfer: a sensitive probe with near-infrared emission from bis(benzoxazole) derivative.
Near-infrared (NIR) emission can offer distinct advantages for biological applications. A fluorescent sensor, Zinhbo-1, based on bis(benzoxazole) ligand with 2,2'-dipicolylamine (DPA) as receptor, was synthesized. In aqueous solution, Zinhbo-1 demonstrates high sensitivity and selectivity for sensing Zn(2+) with about 10-fold enhancement and nanomolar sensitivity (K(d) = 0.29 nM). Moreover, sensor Zinhbo-1 can detect Zn(2+) in near-infrared region (over 700 nm) with large Stokes shift (ca. 230 nm) attributing to the Zn(2+)-induced excited state intramolecular proton transfer (ESIPT).
Department of Chemistry, Maurice Morton Institute of Polymer Science, The University of Akron, OH 44325, USA.
Yongqian
Y
Xu
Yi
Y
Pang
D001583:Benzoxazoles / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011522:Protons; D011789:Quantum Theory; D019265:Spectroscopy, Near-Infrared; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
D001583:Benzoxazoles; D009942:Organometallic Compounds; D011522:Protons; D015032:Zinc