The preparation of glutathione-capped CdTe quantum dots and their use in imaging of cells.
In this paper, different sizes of glutathione-capped CdTe (GSH/CdTe) quantum dots (QDs) have been prepared directly in aqueous solution. The QDs have tunable fluorescence in the range of 510-670 nm, and they also have high photoluminescence quantum yield (PLQY) without any postpreparative treatment. Furthermore, the QDs have strong resistance to photobleaching, and they also have to be considered as cytocompatible. In addition, for the first time, folic acid was covalently conjugated to the GSH/CdTe QDs for imaging of cancer cells, demonstrating their potentially broad application as biolabels.
College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Shandong Normal University, Jinan, People's Republic of China.
Mei
M
Xue
Xu
X
Wang
Hui
H
Wang
Bo
B
Tang
D019187:Cadmium Compounds / Q000737:chemistry / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D003952:Diagnostic Imaging; D005453:Fluorescence; D005978:Glutathione / Q000737:chemistry / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D045663:Quantum Dots; D013691:Tellurium / Q000737:chemistry / Q000494:pharmacology; D014867:Water / Q000737:chemistry*
D019187:Cadmium Compounds; D014867:Water; D005978:Glutathione; D013691:Tellurium; C028337:cadmium telluride