[The pathogenesis of primary immune thrombocytopenia].
Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune-mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathogenesis of ITP.This article aims to provide an overview of our knowledge of the pathogenesis of ITP.
Afsnit 7521, Institut for Inflammationsforskning, Finsenscenter, Rigshospitalet, 2200 København N, Denmark. sif.gudbrandsdottir@gmail.com
Sif
S
Gudbrandsdottir
Henrik
H
Frederiksen
Henrik Sverre
HS
Birgens
Claus Henrik
CH
Nielsen
Ove Juul
OJ
Nielsen
Jesper
J
Stentoft
Hans Carl
HC
Hasselbalch
D001323:Autoantibodies / Q000096:biosynthesis; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D013601:T-Lymphocytes / Q000276:immunology; D034061:Thrombopoiesis / Q000502:physiology
D001323:Autoantibodies