[Physiology in XXI century: natural science and medicine].
Progress of physiology is closely connected with achievements of the adjacent sciences that developed particularly intensively at the end of the XX century. The key role in strategy of physiological investigations is played by study of the nature of regulation of individual processes providing activity of the organism as a whole. By the example of study of renal function there are discussed the issue of integration of its incretory and secretory functions, elucidation of the mechanism of activity of regulatory systems with taking into account the wide diversity of types and subtypes of receptors, interaction of numerous variants of cotransporters, pumps, water and ion channels, which eventually provides the amazing efficiency of the coordinated work of several organs and systems for stabilization of physical-chemical parameters of the internal environment. Development of physiology is of importance for progress of natural science and clinical medicine, as its achievements facilitate discovery of mechanisms of physiological functions, elucidation of defect of the locus underlying dysfunction.
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D000818:Animals; D035843:Biomedical Research / Q000266:history / Q000379:methods* / Q000639:trends; D049674:History, 21st Century; D006801:Humans; D008511:Medicine / Q000379:methods* / Q000639:trends; D010827:Physiology / Q000266:history / Q000379:methods* / Q000639:trends