[EEG, ERP in selective attention paradigm and the level of some metabolites in brain prefrontal cortex].
The preliminary analysis at the first stage of the research has revealed the statistically significant correlations between electrophysiological parameters and the level of several metabolites (determined by magnetic-resonance spectroscopy) in the left dorsolateral prefrontal cortex. The findings are assumed to be due to the individually specific peculiarities of activation of this brain region and its impact on the information processing. The neurophysiological markers of decreased brain functional state are associated with the lower N-acetyl aspartate and choline and higher level of creatin/phosphocreatin in the tested region of prefrontal cortex.
I S
IS
Lebedeva
N A
NA
Semenova
A V
AV
Petriaĭkin
A Iu
AIu
Agafonov
A A
AA
Mitrofanov
T A
TA
Akhadov
D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D001288:Attention / Q000502:physiology*; D015415:Biomarkers / Q000378:metabolism; D001923:Brain Chemistry / Q000502:physiology; D058256:Brain Waves / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D002794:Choline / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010725:Phosphocreatine / Q000378:metabolism*
D015415:Biomarkers; D010725:Phosphocreatine; D001224:Aspartic Acid; C000179:N-acetylaspartate; D002794:Choline