Synthesis of highly selective indole-based sensors for mercuric ion.
Two indole-based fluorescent chemosensors 1 and 2 were prepared and investigated characteristic features with transition metal ions. Sensors 1 and 2 were selective for Hg(2+) ion, among a series of metal ions, in aqueous ethanol (H(2)O-EtOH, 1:2, v/v) with association constants of 5.74 × 10(3) and 4.46 × 10(3) M(-1) and detection limits of 7.4 and 6.8 μM, respectively. Computational results revealed that sensor 1 or 2 with Hg(2+) ion formed 1:1 complex with a central, sandwich-coordinated Hg(2+) ion. Computational calculations provided evidence that a sandwich-coordinated Hg(2+) ion center was formed and the polyoxyethylene spacer acted as a scaffold for bringing functional ligands into a suitable geometry.
Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan.
Huei-Jyun
HJ
Huang
Jiun-Ly
JL
Chir
Hsiu-Jung
HJ
Cheng
Shau-Jiun
SJ
Chen
Ching-Han
CH
Hu
An-Tai
AT
Wu
D005453:Fluorescence; D007211:Indoles / Q000138:chemical synthesis*; D007477:Ions; D008024:Ligands; D057230:Limit of Detection; D008628:Mercury / Q000032:analysis*; D008968:Molecular Conformation
D007211:Indoles; D007477:Ions; D008024:Ligands; D008628:Mercury
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