[Comparative analysis of the DXPas34 regulatory region in rodents].
Mouse X chromosome inactivation center contains the DXPas34 minisatellite locus which plays an important role in expression regulation of the Tsix and Xist genes, involved into female dosage compensation. Comparative analysis of the DXPas34 locus from mouse, rat, and four common vole species revealed similar organization of this region in the form of tandem repeat blocks. A search for functionally important elements in this locus showed that all the species examined carried the conservative motif monomers, which could be involved in regulation of X inactivation.
A A
AA
Malakhova
M S
MS
Piatkova
E A
EA
Elisafenko
A I
AI
Shevchenko
A É
AÉ
Kel'
S M
SM
Zakiian
D000818:Animals; D003411:Arvicolinae; D033481:Chromosomes, Mammalian / Q000235:genetics*; D005260:Female; D051379:Mice; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated / Q000235:genetics*; D051381:Rats; D050436:Regulatory Elements, Transcriptional / Q000235:genetics*; D020080:Tandem Repeat Sequences / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics*; D049951:X Chromosome Inactivation / Q000235:genetics*
D062085:RNA, Long Noncoding; D022661:RNA, Untranslated; C465658:Tsix transcript, mouse; C077885:XIST non-coding RNA