Relationship between adolescent risk preferences on a laboratory task and behavioral measures of risk-taking.
OBJECTIVE
The goal of the study was to assess individual differences among adolescents regarding risk-taking behavior in the laboratory. The second aim was to evaluate whether the laboratory-based risk-taking behavior is associated with other behavioral and psychological measures associated with risk-taking behavior.


METHODS
A total of 82 adolescents with no personal history of psychiatric disorder completed a computerized decision-making task, the Wheel of Fortune. On the basis of the choices made between clearly defined probabilities and real monetary outcomes, this task assesses risk preferences when participants are confronted with potential rewards and losses. The participants also completed a variety of behavioral and psychological measures associated with risk-taking behavior.


RESULTS
Performance on the task varied on the basis of probability and anticipated outcomes. In the winning sub-task, participants selected low-probability-high-magnitude reward (high-risk choice) less frequently than high-probability-low-magnitude reward (low-risk choice). In the losing sub-task, participants selected low-probability-high-magnitude loss more often than high-probability-low-magnitude loss. On average, the selection of probabilistic rewards was optimal and similar to performance in adults. There were, however, individual differences in performance, and one-third of the adolescents made high-risk choice more frequently than low-risk choice while selecting a reward. After controlling for sociodemographic and psychological variables, high-risk choice on the winning task predicted "real-world" risk-taking behavior and substance-related problems.


CONCLUSIONS
These findings highlight individual differences in risk-taking behavior. Regarding validity of the Wheel of Fortune task, the preliminary data suggest that it might be a valuable laboratory tool for studying behavioral and neurobiological processes associated with risk-taking behavior in adolescents.
Department of Psychiatry, University of Texas Southwestern Medical Center, 5223 Harry Hiles Blvd., Dallas, TX 75390-9101, USA. uma.rao@utsouthwestern.edu
Uma
U
Rao
Tanuj
T
Sidhartha
Karen R
KR
Harker
Anup S
AS
Bidesi
Li-Ann
LA
Chen
Monique
M
Ernst
D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D003657:Decision Making; D005260:Female; D006801:Humans; D007206:Individuality; D008297:Male; D019964:Mood Disorders / Q000523:psychology; D011336:Probability; D012201:Reward; D012309:Risk-Taking; D012565:Schizophrenic Psychology; D019966:Substance-Related Disorders / Q000523:psychology
Neurosci Biobehav Rev. 2000 Jun;24(4):417-63
10817843
Arch Dis Child. 1969 Jun;44(235):291-303
5785179
J Pers Soc Psychol. 1988 Jun;54(6):1063-70
3397865
Neurosci Biobehav Rev. 2009 Mar;33(3):367-82
19028521
Arch Dis Child. 1970 Feb;45(239):13-23
5440182
J Abnorm Child Psychol. 2001 Dec;29(6):499-511
11761284
J Adolesc. 1993 Jun;16(2):153-68
8376640
Neuroimage. 2009 Jan 15;44(2):600-9
18804540
Neuroimage. 2005 May 1;25(4):1279-91
15850746
J Neurosci. 2006 Sep 13;26(37):9530-7
16971537
Neuropsychologia. 2004;42(13):1838-51
15351632
J Am Acad Child Adolesc Psychiatry. 1997 Jul;36(7):980-8
9204677
Neurosci Biobehav Rev. 2008 Oct;32(8):1507-18
18588911
Neurosci Biobehav Rev. 2004 May;28(3):343-51
15225976
MMWR Surveill Summ. 2008 Jun 6;57(4):1-131
18528314
Arch Gen Psychiatry. 1982 Jan;39(1):53-8
7055408
Ann N Y Acad Sci. 2004 Jun;1021:1-22
15251869
Neuropsychologia. 2001;39(4):376-89
11164876
Neuropsychologia. 2007 Mar 25;45(6):1270-9
17118409
J Affect Disord. 2004 Oct;82 Suppl 1:S89-S101
15571794
Neuropsychol Rev. 2009 Mar;19(1):102-14
19194801
J Affect Disord. 2009 Nov;118(1-3):69-78
19261334
Psychol Rep. 1978 Dec;43(3 Pt 2):1247-55
746091
Br J Addict. 1990 Nov;85(11):1501-4
2285849
Arch Gen Psychiatry. 1977 Oct;34(10):1229-35
911222
Dev Sci. 2007 Mar;10(2):F8-F14
17286837
J Exp Psychol Appl. 2002 Jun;8(2):75-84
12075692
Br Med J. 1970 May 23;1(5707):439-43
5420206
Neuroimage. 2007 Jul 15;36(4):1253-62
17521924
Dev Rev. 2008 Mar;28(1):1-11
19255598
J Am Acad Child Adolesc Psychiatry. 2006 Sep;45(9):1059-1067
16926613