Childhood acute generalized exanthematous pustulosis induced by oral ketoconazole.
Acute generalized exanthematous pustulosis is a rare disorder characterized by an acute onset of generalized, nonfollicular, pustular eruption associated with fever. It is usually drug-induced and is uncommon in children. We report a 12-year-old girl with acute generalized exanthematous pustulosis induced by oral ketoconazole. To our knowledge, in spite of its relatively frequent use, acute generalized exanthematous pustulosis due to ketoconazole has not been previously reported.
Department of Dermatology and Venereology, Medical University, Sofia, Bulgaria. mitev@medfac.acad.bg
Ljubka
L
Miteva
Miroslava
M
Kadurina
Robert A
RA
Schwartz
D000208:Acute Disease; D000935:Antifungal Agents / Q000009:adverse effects*; D002180:Candidiasis, Oral / Q000517:prevention & control; D002648:Child; D003875:Drug Eruptions / Q000209:etiology*; D005076:Exanthema / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000008:administration & dosage / Q000009:adverse effects*
D000935:Antifungal Agents; D007654:Ketoconazole