Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP.
In this issue of Molecular Cell, Ahearn et al. (2011) identified FKBP12 as a novel regulator of Ras signaling through its modulation of depalmitoylation of H-Ras and its recycling from plasma membrane to the Golgi.
Department of Pharmacology, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA. joliu@jhu.edu
Jun O
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Denis V
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Yongjun
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