Compression of DNA sequence reads in FASTQ format.
BACKGROUND
Modern sequencing instruments are able to generate at least hundreds of millions short reads of genomic data. Those huge volumes of data require effective means to store them, provide quick access to any record and enable fast decompression.


RESULTS
We present a specialized compression algorithm for genomic data in FASTQ format which dominates its competitor, G-SQZ, as is shown on a number of datasets from the 1000 Genomes Project (www.1000genomes.org).


BACKGROUND
DSRC is freely available at http:/sun.aei.polsl.pl/dsrc.
Institute of Informatics, Silesian University of Technology, Akademicka 16, 44-100 Gliwice, Poland. sebastian.deorowicz@polsl.pl
Sebastian
S
Deorowicz
Szymon
S
Grabowski
D000465:Algorithms; D001483:Base Sequence; D019295:Computational Biology / Q000379:methods; D044962:Data Compression / Q000379:methods*; D023281:Genomics; D020407:Internet; D017422:Sequence Analysis, DNA