Liver cirrhosis induced by porphyria cutanea tarda: a case report and review.
Porphyria cutanea tarda (PCT) is a metabolic disorder that results in a decrease in uroporphyrinogen decarboxylase activity. It is characterized by photosensitivity, bullae formation, and skin pigmentation. There are four types of PCT: acquired, familial, toxic, and hepatoerythropoietic. Uroporphyrin levels are elevated in the urine of PCT patients. PCT can be differentiated from other porphyrias by its clinical characteristics and the porphyrin levels in the serum, erythrocytes, urine, and feces. This metabolic disorder can lead to liver dysfunction as well as histological changes such as fatty infiltration or hepatic fibrosis. PCT rarely manifests as liver cirrhosis. We report herein a case of PCT-induced liver cirrhosis that progressed to hepatic failure.
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, Korea.
Kwang Gyun
KG
Lee
Jong Jin
JJ
Hyun
Yeon Seok
YS
Seo
Bora
B
Keum
Hyung Joon
HJ
Yim
Yoon Tae
YT
Jeen
Hong Sik
HS
Lee
Hoon Jai
HJ
Chun
Chang Duck
CD
Kim
Ho Sang
HS
Ryu
Soon Ho
SH
Um
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