Entropy-driven molecular switch and signal amplification for homogeneous SNPs detection.
An approach was developed to rapidly and sensitively detect SNP in homogeneous solution based on an entropy-driven molecular switch and isothermal polymerase amplification reaction without addition of exogenous primers.
State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
Chao
C
Shi
Chunhui
C
Zhao
Qingjie
Q
Guo
Cuiping
C
Ma
D004247:DNA / Q000235:genetics; D019277:Entropy; D006801:Humans; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000379:methods*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012996:Solutions; D013050:Spectrometry, Fluorescence
D012996:Solutions; D004247:DNA