Fusobacterium necrophorum endocarditis Case report and review of the literature.
Fusobacterium necrophorum is a gram-negative anaerobic bacillus that can cause serious systemic infections typically in previously healthy young adults. Lemierre's syndrome, also known as post-anginal sepsis or necrobacillosis, is the infection most usually associated with F. necrophorum. However, F. necrophorum is also a very rare cause of anaerobic endocarditis. Mortality and rates of thromboembolism are high with F. necrophorum endocarditis. In this article, we describe a case of F. necrophorum native valve infective endocarditis. The patient was treated with penicillin plus clindamycin followed by penicillin alone for 6 weeks resulting in complete resolution of infection.
Section on Infectious Diseases, Department of Internal Medicine, UAB Health Center Montgomery, Montgomery, AL 36116, USA. jsamant@uabmontgomery.com
Jyoti S
JS
Samant
James E
JE
Peacock
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004696:Endocarditis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005674:Fusobacterium Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005675:Fusobacterium necrophorum / Q000502:physiology*; D006801:Humans; D007601:Jugular Veins / Q000473:pathology; D008169:Lung Abscess / Q000150:complications / Q000188:drug therapy; D008297:Male; D018805:Sepsis / Q000150:complications / Q000188:drug therapy; D013927:Thrombosis / Q000150:complications / Q000175:diagnosis; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents