[Study on the content of curcumin by HPLC and the anti-tumor effect in vivo from different processed products of Curuma kwangsiensis].
OBJECTIVE
To determine curcumin content by HPLC and observe the antitumor effects in vivo from different processed products of Curuma kwangsiensis.


METHODS
We determined the content of curcumin by HPLC from different processed products of Curuma kwangsiensis and studied the anti-tumor effects in vivo by establishing S180 transplanted tumors model in mice.


RESULTS
The content of curcumin in different processed products of Curuma kwangsiensis as follows: primitive > vinegar-fried > vinegar-cooked. Different processed products had anti-tumor effects in the tumor-bearing mice. The vinegar-fried group and vinegar-cooked group showed obvious effect of inhibiting tumor growth than the primitive group.


CONCLUSIONS
Different processed methods may have some affection to the quality of Curuma kwangsiensis.
Faculty of Pharmacy, GuangXi Traditional Chinese Medical Univercity, Nanning 530001, China. bbythemoon@yahoo.com.cn
Bao
B
Qin
Jin-Xian
JX
Xie
Hai-Ling
HL
Yang
Ping
P
Xiong
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002851:Chromatography, High Pressure Liquid; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology*; D005260:Female; D006358:Hot Temperature; D008099:Liver / Q000187:drug effects; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D027343:Rhizome / Q000737:chemistry; D012510:Sarcoma 180 / Q000473:pathology*; D013154:Spleen / Q000187:drug effects; D013678:Technology, Pharmaceutical / Q000379:methods
D000970:Antineoplastic Agents; D003474:Curcumin