Detection of hepatitis C virus and antibodies in postmortem blood and bloodstains.
To evaluate the risk of accidental hepatitis C virus (HCV) infection, we examined whether anti-HCV antibodies and HCV RNA were detectable in HCV-infected blood samples from living donors, cadavers, and bloodstains. We showed that even after blood has left the body for several days, anti-HCV antibodies and HCV RNA may persist in it.
Department of Forensic Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo, Kyoto 602-8566, Japan.
Tomokazu
T
Takasaka
Yoshito
Y
Itoh
Hiroto
H
Kaneko
Hiroshi
H
Ikegaya
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001769:Blood / Q000276:immunology* / Q000821:virology*; D001801:Blood Stains; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D018570:Risk Assessment; D013997:Time Factors
D018937:Hepatitis C Antibodies
J Gen Virol. 1994 Sep;75 ( Pt 9):2393-8
8077938
Virol J. 2010 Aug 26;7:203
20796270
J Med Virol. 2010 Feb;82(2):257-62
20029811
Science. 1999 Jul 2;285(5424):110-3
10390360
Indian J Med Microbiol. 2010 Jan-Mar;28(1):54-6
20061766
Forensic Sci Int. 2010 Feb 25;195(1-3):167.e1-6
20005650
Science. 1997 Jul 25;277(5325):570-4
9228008
Nat Med. 2001 Aug;7(8):927-33
11479625
Nat Med. 2005 Jul;11(7):791-6
15951748
J Clin Microbiol. 1994 Apr;32(4):884-92
7913097
Hepatology. 1994 Dec;20(6):1405-11
7982639
J Virol Methods. 2008 Jan;147(1):78-85
17868913
Forensic Sci Int. 2007 Nov 15;173(1):41-6
17324543
Forensic Sci Int. 2004 Jan 28;139(2-3):169-72
15040911
Transfusion. 1993 Jan;33(1):7-13
7678709
Int J Legal Med. 2002 Aug;116(4):242-5
12420704
Int J Infect Dis. 2006 Jul;10(4):272-7
16564719
J Gen Virol. 1992 Mar;73 ( Pt 3):673-9
1312125
J Med Virol. 2010 May;82(5):903-8
20336724