Autonomic dysfunction and risk stratification assessed from heart rate pattern.
The modulation of the autonomic nervous system (ANS) under physiological and pathophysiological conditions is in focus of recent research. Many patients with cardio- and cerebrovascular diseases display features of sympathovagal dysregulation. Measuring specific ANS parameters could improve risk stratification. Thus, the early diagnosis of ANS dysfunction in these patients poses a great challenge with high prognostic relevance.The most relevant methods and measures of Heart Rate Variability (HRV) analysis and HRV monitoring will be described in detail in this chapter. The grown importance of these easily obtainable heart rate patterns in stratifying the risk of patients with myocardial infarction and heart failure as well as ischemic stroke will be demonstrated based on recent clinical studies. In order to perspectively improve clinical management of these patients further large scale clinical investigations on the role of ANS dysfunction will be useful.
Department of Neurology, Friedrich-Schiller-University of Jena, Erlanger Allee 101, D-07747 Jena, Germany.
A
A
Günther
O W
OW
Witte
D
D
Hoyer
Neurology. 2001 Sep 11;57(5):833-8
11552013
J Crit Care. 2008 Jun;23(2):255-62
18538221
Neuropsychopharmacology. 2003 Jul;28 Suppl 1:S48-53
12827144
Am J Cardiol. 1992 Apr 1;69(9):891-8
1550018
Circulation. 2003 Sep 9;108(10):1221-6
12939209
Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2297-301
11607165
Neurology. 2004 May 25;62(10):1822-6
15159485
Am J Cardiol. 1999 Mar 15;83(6):836-9
10190395
Stroke. 2004 Sep;35(9):2094-8
15272134
Cerebrovasc Dis. 1998 Mar-Apr;8(2):118-23
9548011
Circulation. 2003 Feb 4;107(4):565-70
12566367
Ann Noninvasive Electrocardiol. 2008 Apr;13(2):191-207
18426445
Nat Rev Neurosci. 2005 Oct;6(10):775-86
16163382
Chaos. 1995 Mar;5(1):88-94
12780160
Int J Cardiol. 2006 Apr 14;108(3):359-69
15979171
Stroke. 2005 Aug;36(8):1710-5
16020766
Crit Care Med. 2005 Sep;33(9):1994-2002
16148471
Eur Heart J. 2005 Feb;26(4):357-62
15618038
Neuroreport. 2004 Feb 9;15(2):357-61
15076768
Circulation. 1998 Aug 11;98(6):547-55
9714112
Circulation. 1996 Mar 1;93(5):1043-65
8598068
Eur Heart J. 2000 Mar;21(6):475-82
10681488
Eur J Neurol. 2007 Aug;14(8):917-22
17662015
Biochem Pharmacol. 1998 Nov 1;56(9):1079-87
9802316
Physiol Meas. 2007 Sep;28(9):1067-77
17827654
Am J Physiol Heart Circ Physiol. 2000 Jun;278(6):H2039-49
10843903
Comput Methods Programs Biomed. 2006 Mar;81(3):246-55
16483685
Biol Cybern. 1998 Jan;78(1):71-8
9485587
Circulation. 1998 Oct 13;98(15):1510-6
9769304
Stroke. 2007 Feb;38(2):276-80
17218610
Sports Med. 2003;33(12):889-919
12974657
Hypertension. 1988 Aug;12(2):214-22
3410530
Stroke. 1999 Jul;30(7):1307-11
10390300
Stroke. 2005 May;36(5):1026-30
15802639
Stroke. 1998 Feb;29(2):447-53
9472888
Crit Care Med. 2008 Mar;36(3):1025-7
18431317
Hypertension. 1988 Dec;12(6):600-10
3203964
Lancet. 1999 Apr 24;353(9162):1390-6
10227219
Stroke. 1999 May;30(5):1008-13
10229736
Circulation. 1996 Jun 15;93(12):2142-51
8925583
IEEE Trans Biomed Eng. 2005 Apr;52(4):584-92
15825860
Lancet. 1998 Feb 14;351(9101):478-84
9482439
Am J Physiol Regul Integr Comp Physiol. 2002 Sep;283(3):R789-97
12185014
Neurology. 2007 Dec 11;69(24):2249-55
18071145
Cardiovasc Res. 1996 Mar;31(3):419-33
8681329
IEEE Eng Med Biol Mag. 2007 Nov-Dec;26(6):30-2
18189084
Nat Med. 1998 Jul;4(7):808-13
9662372
Heart. 2006 Aug;92(8):1055-63
16387812
Heart Rhythm. 2009 Apr;6(4):546-52
19324318
Stroke. 1997 Nov;28(11):2150-4
9368556
Sleep. 2007 Jul;30(7):913-9
17682663
Chaos. 1995;5(1):82-7
11538314
Biomed Tech (Berl). 2006 Oct;51(4):276-8
17061957
Crit Care Med. 2005 Sep;33(9):2128-30
16148497
Crit Care Clin. 2008 Jan;24(1):149-63, ix
18241783
IEEE Eng Med Biol Mag. 2007 Nov-Dec;26(6):19-24
18189082
IEEE Eng Med Biol Mag. 2007 Nov-Dec;26(6):33-7
18189085
Med Biol Eng Comput. 2006 Dec;44(12):1031-51
17111118
Pacing Clin Electrophysiol. 2008 Feb;31(2):214-20
18233975
Arch Intern Med. 2005 Jul 11;165(13):1486-91
16009863
Phys Rev Lett. 2002 Aug 5;89(6):068102
12190613
Ann Noninvasive Electrocardiol. 2005 Jan;10(1):88-101
15649244
Nature. 2000 May 25;405(6785):458-62
10839541
Stroke. 1996 Feb;27(2):247-51
8571418
Stroke. 1994 Jan;25(1):113-6
8266357
Circulation. 2008 Sep 30;118(14):1497-1518
18833586
IEEE Eng Med Biol Mag. 2007 Nov-Dec;26(6):14-8
18189081