[Gender differences in action Fenotropil and its structural analog--compound RGPU-95 on anxiety-depressive behavior animals].
Fenotropil and its structural analog--compound RGPU-95 to a greater extent reduce the severity of anxious and depressive behavior in male rats than in females. On expression of the anxiolytic compound RGPU-95 significantly exceeds Fenotropil, but inferior to Diazepam; of antidepressant activity--comparable to Melipramin and exceeds Fenotropil.
I N
IN
Tiurenkov
V V
VV
Bagmetova
A V
AV
Shishkina
V M
VM
Berestovitskaia
O S
OS
Vasil'eva
E S
ES
Ostrogliadov
D000818:Animals; D001007:Anxiety / Q000188:drug therapy / Q000503:physiopathology*; D001522:Behavior, Animal / Q000187:drug effects*; D003863:Depression / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D018757:GABA Modulators / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012727:Sex Characteristics
D018757:GABA Modulators