Epidemiology of lung cancer in women: risk factors, survival, and screening.
OBJECTIVE
Lung cancer remains the leading cause of cancer mortality in both men and women. Tobacco use causes the vast majority of lung cancer in women but does not explain all cases, because about one in five women who develop lung cancer have never smoked.


CONCLUSIONS
Environmental exposures, genetic predisposition, hormonal factors, and viral infection may all play a role in lung cancer in women. A better understanding may provide an avenue to more effective screening, diagnosis, and therapy.
Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, 22 S. Greene St., Baltimore, MD 21201, USA. skligerman@umm.edu
Seth
S
Kligerman
Charles
C
White
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000556:secondary; D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000000981:diagnostic imaging / Q000453:epidemiology; D000328:Adult; D015984:Causality; D015897:Comorbidity; D055088:Early Detection of Cancer / Q000706:statistics & numerical data*; D004781:Environmental Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000009:adverse effects; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D007239:Infections / Q000453:epidemiology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data; D008875:Middle Aged; D011859:Radiography; D011886:Radon / Q000009:adverse effects; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000453:epidemiology; D015996:Survival Rate; D014028:Tobacco Smoke Pollution / Q000009:adverse effects / Q000706:statistics & numerical data; D014481:United States / Q000453:epidemiology
D004785:Environmental Pollutants; D014028:Tobacco Smoke Pollution; D011886:Radon