[Research progress of biomarker COMP in osteoarthritis].
Cartilage oligomeric matrix protein (COMP) is a potential biomarker for joint destruction associated with osteoarthritis, which is first and best investigated biomarkers to reflect osteoarthritis occurs, progress and the prognosis. In this article, multiple uses and related reports of COMP are summarized briefly to promote further investigation of COMP.
Department of Orthopaedics and Trauma Surgery, the Third Affiliated Hospital of Wenzhou Medical College, Zhejiang, China.
Tai-Hang
TH
Zhu
Chun-Yuan
CY
Cai
Lei
L
Zhang
D015415:Biomarkers / Q000097:blood*; D064236:Cartilage Oligomeric Matrix Protein; D016326:Extracellular Matrix Proteins / Q000097:blood* / Q000737:chemistry / Q000378:metabolism; D006023:Glycoproteins / Q000097:blood* / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D064235:Matrilin Proteins; D010003:Osteoarthritis / Q000097:blood / Q000175:diagnosis*; D011379:Prognosis
D015415:Biomarkers; D064236:Cartilage Oligomeric Matrix Protein; D016326:Extracellular Matrix Proteins; D006023:Glycoproteins; D064235:Matrilin Proteins; C577553:TSP5 protein, human