[Isolated oligodontia: a case presentation and review of the literature].
Tooth agenesis is a common developmental anomaly that appears in 2.2-10% of the general population (excluding agenesis of third molars). Congenital tooth agenesis can be either Hypodontia (agenesis of fewer than six teeth excluding third molars) or Oligodontia (agenesis of more than six teeth excluding third molars). Oligodontia can occur either as an isolated condition (non-syndromic oligodontia) or be associated with cleft lip\palate and other genetic syndromes (syndromatic oligodontia). The purpose of this article is to present an unusual case of non-syndromic oligodontia and describe the dental treatment for this condition. The patient was a 25 years old healthy male with a chief complaint of multiple teeth agenesis and TMJ dysfunction. The family history revealed that the mother, grandmother and siblings have also multiple teeth agenesis. Clinical examination revealed missing of nine teeth in the maxilla (12,13, 15,15, 17, 23, 24, 25, 27) and 10 teeth in the mandible (32, 33, 34, 35, 37, 42, 43, 44, 45, 47). The patient's dental treatment plan included preparing provisional over-dentures, orthodontic treatment and dental implants (after extractions of the deciduous teeth). In the discussion of the article the pathology and the genetics of oligodontia are reviewed.
Dept. of Oral and Maxillofacial Surgery, Sheba Medical Center, Israel.
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Frenkel
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Blinder
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Penn
D000328:Adult; D000848:Anodontia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D003744:Dental Enamel Hypoplasia / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D004476:Ectodermal Dysplasia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D006801:Humans; D015994:Incidence; D053779:Latent TGF-beta Binding Proteins / Q000235:genetics; D051957:MSX1 Transcription Factor / Q000235:genetics; D008297:Male; D011859:Radiography
D053779:Latent TGF-beta Binding Proteins; D051957:MSX1 Transcription Factor; C484083:MSX1 protein, human