Usage of 64-detector-row spiral computed tomography volumetry in preoperative volume prediction in living donor liver transplantation in children.
OBJECTIVE
To investigate the correlation between the graft volume calculated by 64-detector-row spiral computed tomography (CT) and the graft weight measured during the living donor liver transplantation (LDLT) operation, and try to get an equation to help determine the possible weight of graft before operation.


METHODS
23 donors with left lateral lobe LDLT were enrolled to undergo 64-detector-row spiral CT and the imaging data at the hepatic venous phase was used for whole and partial liver volumetric measurement on a dedicated image postprocessing workstation. The resected part of donor liver was weighed during the operation. Statistical analysis with SPSS15.0 was used to analyze the correlation between the estimated liver volume by CT and the actual graft weight.


RESULTS
The graft volume calculated preoperatively by CT (293.35 ± 53.43 ml) was significantly larger than measured graft weight during the operation (252.82 ± 50.96 g) (P < 0.05). All corresponding pre- and intraoperative data correlated significantly (R = 0.885) (P < 0.001). Intraoperatively expected weight (W (intraop)) in grams and volume calculated preoperatively by CT (V (preop)) in milliliters can be calculated with the equation W (intraop) (g) = 0.844 × V (preop) (ml) + 5.271.


CONCLUSIONS
Liver volume calculated by 64-detector-row spiral CT preoperatively can predict the actual graft weight, which is very useful in donor selection in LDLT.
Department of Hepato-biliary Surgery, Children's Hospital, Chongqing Medical University, Chongqing, 400014, China.
Ying-Cun
YC
Li
Yan
Y
Hu
Ming-Man
MM
Zhang
Xian-Qing
XQ
Jin
Xiao
X
Fan
Cong-Lun
CL
Pu
Chun-Bao
CB
Guo
Quan
Q
Kang
Xiao-Ke
XK
Dai
Yu-Hua
YH
Deng
D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D057234:Preoperative Period; D012189:Retrospective Studies; D036542:Tomography, Spiral Computed; D055815:Young Adult
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