Immunopathogenetic and pharmacological aspects of interstitial lung diseases.
Interstitial lung diseases (ILDs) are inflammatory diseases characterized by slow and progressive destruction of alveolar-capillary functional units, often leading to respiratory failure and death. A first stage of alveolitis and a following stage of fibrosis provoke an anatomical distortion of the peripheral airways and the interstitium, and for their smoldering evolution and non-specificity of symptoms ILDs may remain undiagnosed and untreated for a long time. In this review we exploited the immunopathogenetic aspects and the therapeutical approaches to this frequently unrecognized and severe disease.
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Mazzoccoli
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De Cata
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De Pinto
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De Matthaeis
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Vendemiale
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001706:Biopsy; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D011379:Prognosis; D012129:Respiratory Function Tests
D000305:Adrenal Cortex Hormones