Estimating the impact of human papillomavirus (HPV) vaccination on HPV prevalence and cervical cancer incidence in Mali.
Human papillomavirus vaccines have potential to reduce cervical cancer incidence and mortality; however, cultural and economic barriers may hinder success in developing countries. We assessed impact of a single vaccine campaign in Mali with use of mathematical modeling. Our model shows that decreases in the prevalence of Human papillomavirus infection are proportional to achieved vaccination coverage.
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA. ktracy@epi.umaryland.edu
LaRee
L
Tracy
Holly D
HD
Gaff
Colleen
C
Burgess
Samba
S
Sow
Patti E
PE
Gravitt
J Kathleen
JK
Tracy
D005260:Female; D006801:Humans; D015994:Incidence; D008302:Mali / Q000453:epidemiology; D008962:Models, Theoretical; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D015995:Prevalence; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D014611:Vaccination / Q000706:statistics & numerical data*
D053918:Papillomavirus Vaccines
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