Early management of severe acute pancreatitis.
Significant literature on the management of acute severe acute pancreatitis has emerged in recent years. The new information ranges from data on newer single or multiparameter severity assessment tools and classification systems to therapeutic modalities. However, a few basic issues-the ideal severity assessment modality, volume of intravenous fluids required in the first 48 to 72 h, and the role of prophylactic antibiotics-are still not clear and are subject to controversy. The International Working Group has devised the Revised Atlanta Classification, which will be published soon. This new classification is eagerly awaited worldwide, and hopefully clarifies many of the problems of the original Atlanta Classification. In this article, we discuss the developments that have arisen in the past 2 to 3 years concerning the classification, prognostication, and early management of severe acute pancreatitis.
Miles and Shirley Fiterman Center for Digestive Diseases, 200 First Street SW, Mayo Clinic, Rochester, MN 55905, USA. rup_talukdar@yahoo.com
Rupjyoti
R
Talukdar
Santhi
S
Swaroop Vege
D000208:Acute Disease; D019072:Antibiotic Prophylaxis; D002760:Cholangiopancreatography, Endoscopic Retrograde; D004750:Enteral Nutrition; D005440:Fluid Therapy; D006801:Humans; D010195:Pancreatitis / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D019283:Pancreatitis, Acute Necrotizing / Q000517:prevention & control / Q000628:therapy; D010288:Parenteral Nutrition; D011379:Prognosis; D012720:Severity of Illness Index; D016717:Sphincterotomy, Endoscopic
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