Novel procedure- and device-based strategies in the management of systemic hypertension.
Despite the considerable advances in the treatment of hypertension that have been made over the past few decades, adequate management and control of this condition remains poor, and efforts are ongoing to develop new strategies to improve related outcomes. Novel therapeutic approaches to the management of systemic hypertension fall into two major categories: (i) those that seek to improve blood pressure-lowering efficacy using new therapeutic strategies in addition to standard non-pharmacological and pharmacological approaches and (ii) novel ways to optimize and improve the efficacy and utility of existing therapies. Novel procedure- and device-based strategies to control hypertension include renal sympathetic denervation and baroreflex sensitization. These two techniques will be the focus of the present review.
Monash Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University/Alfred Hospital, Melbourne, VIC 3004, Australia. henry.krum@med.monash.edu.au
Henry
H
Krum
Markus
M
Schlaich
Paul
P
Sobotka
Ingrid
I
Scheffers
Abraham A
AA
Kroon
Peter W
PW
de Leeuw
D017704:Baroreflex; D004599:Electric Stimulation Therapy / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D013562:Sympathectomy / Q000379:methods*