Odontogenic tumors: a 5-year retrospective study in a Brazilian population and analysis of 3406 cases reported in the literature.
OBJECTIVE
The objective of this study was to analyze the frequency and distribution of odontogenic tumors in Fortaleza, Brazil, and compare the findings with those reported in the literature.


METHODS
A total of 6231 oral lesions retrieved from 5 anatomic pathology services in Fortaleza, Brazil, over a 5-year period, were reviewed. In addition, the literature was searched for studies on odontogenic tumors (OTs) according to the 2005 WHO classification.


RESULTS
Within the total 6231 oral lesions, 185 (2.97%) were OTs, all benign. OTs presented a female predilection, with a male:female ratio of 0.62:1.00. These neoplasms occurred over a wide range of ages (1 to 78 years), with a mean of 30.5 years. Ameloblastomas, keratocystic odontogenic tumors, and odontomas were the most frequent OT types.


CONCLUSIONS
OTs are rare neoplasms and appear to show geographic variations. In Fortaleza, Brazil, they are more common in female patients, with ameloblastoma followed by keratocystic odontogenic tumors as the most frequent OTs.
Department of Pathology, Fortaleza University School of Medicine, Fortaleza, Ceara, Brazil. rlimaverde@unifor.br
Rafael Lima Verde
RL
Osterne
Renata Galvão de Matos
RG
Brito
Ana Paula Negreiros Nunes
AP
Alves
Roberta Barroso
RB
Cavalcante
Fabrico Bitu
FB
Sousa
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D009808:Odontogenic Tumors / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D017678:Sex Distribution; D012744:Sex Ratio; D055815:Young Adult