Junín virus. A XXI century update.
Junín virus of the Arenaviridae family is the etiological agent of Argentine hemorrhagic fever, a febrile syndrome causing hematological and neurological symptoms. We review historical perspectives of current knowledge on the disease, and update information related to the virion and its potential pathogenic mechanisms.
Biotechnology and Molecular Biology Institute, CONICET-UNLP, calle 49 y 115, 1900 La Plata, Argentina. rmg@biol.unlp.edu.ar
Ricardo M
RM
Gómez
Carolina
C
Jaquenod de Giusti
Maria M
MM
Sanchez Vallduvi
Jesica
J
Frik
Maria F
MF
Ferrer
Mirta
M
Schattner
D000818:Animals; D006478:Hemorrhagic Fever, American / Q000503:physiopathology* / Q000821:virology; D006801:Humans; D018051:Junin virus / Q000145:classification / Q000472:pathogenicity* / Q000502:physiology* / Q000648:ultrastructure; D023421:Models, Animal; D014779:Virus Replication / Q000502:physiology