Uvacalols I, J and K: new polyoxygenated cyclohexenes with all trans relative configurations from the roots of Uvaria calamistrata Hance.
Three new polyoxygenated cyclohexene derivatives with all trans relative configurations, named uvacalols I, J and K (1-3), were isolated from the roots of Uvaria calamistrata Hance. Their structures were determined to be (1R, 2S, 3S, 4R)-1-ethoxyl-5-benzoyloxymethylcyclohex-5-en-2,4-diol-3-benzoate (1), 1-ethoxyl-5-benzoyloxymethylcyclohex-5-en-3,4-diol-2-benzoate (2), and 5-benzoyloxymethylcyclohex-5-en-1,2,4-triol-3-benzoate (3), respectively, by extensive NMR experiments and chemical derivatisation.
Guangdong Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Institute of TCM and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. guangxzh@sina.com
Guang-xiong
GX
Zhou
Ruo-yun
RY
Chen
De-quan
DQ
Yu
D029061:Annonaceae / Q000737:chemistry*; D001565:Benzoates / Q000302:isolation & purification*; D003510:Cyclohexanes / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
D001565:Benzoates; D003510:Cyclohexanes