Peripheral muscle dysfunction and chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease is a systemic disease that includes significant adverse effects on muscle function, with varied changes to the structure and metabolism of the peripheral muscles. This review evaluates the evidence for the mechanisms that mediate these changes and the significance of the diminished muscle function.
Department of General Medicine, Darent Valley Hospital, Dartford.
Lea
L
Breunung
Mike
M
Roberts
D006801:Humans; D018763:Muscle Fatigue / Q000502:physiology; D018482:Muscle, Skeletal / Q000201:enzymology; D009135:Muscular Diseases / Q000201:enzymology / Q000209:etiology / Q000503:physiopathology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000503:physiopathology*