Cytotoxicity micropollutant removal in a crossflow membrane bioreactor.
The application of membrane bioreactor (MBR) technology was investigated with the aim of evaluating its potential for cytostatic drug and cytotoxicity bioremoval. The toxicity removal was assessed from biomarker test. CP removal of up to 80% was achieved under the operating conditions studied (HRT of 48 h and a SRT of 50 days). The increase of TMP was associated with an increase of supernatant toxicity as if fouling led to retention of the toxicity. Peaks of supernatant cytotoxicity were correlated with peaks in supernatant humic acid contents. It may suggest that molecules with a toxic effect may be adsorbed or entrapped in humic acids substances. Our study then points out that advances in wastewater treatment using an MBR can provide a suitable process for lowering CP concentrations before discharge into the aqueous environment. However, a tertiary treatment is necessary if complete elimination of toxicity is targeted.
Université de Toulouse, Laboratoire de Génie Chimique, UMR 5503, Site de Labège, BP 84234, Campus INP-ENSIACET, 4 allée Emile Monso, 31432 Toulouse cedex 4, France.
Luis F
LF
Delgado
Virginie
V
Faucet-Marquis
Annie
A
Pfohl-Leszkowicz
Christophe
C
Dorandeu
Benedicte
B
Marion
Sylvie
S
Schetrite
Claire
C
Albasi
D019149:Bioreactors; D016923:Cell Death / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D003520:Cyclophosphamide / Q000302:isolation & purification* / Q000633:toxicity*; D056945:Hep G2 Cells; D006801:Humans; D008567:Membranes, Artificial; D010539:Permeability / Q000187:drug effects; D010865:Pilot Projects; D011312:Pressure; D012212:Rheology / Q000295:instrumentation*; D014874:Water Pollutants, Chemical / Q000302:isolation & purification* / Q000633:toxicity*
D008567:Membranes, Artificial; D014874:Water Pollutants, Chemical; D003520:Cyclophosphamide