Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures.
Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy. marcella.bellani@univr.it
Marcella
M
Bellani
Nicola
N
Dusi
Paolo
P
Brambilla
D001921:Brain / Q000473:pathology*; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D017063:Outcome Assessment, Health Care; D012559:Schizophrenia / Q000473:pathology*