[Efficacy of prostaglandin E1 and systemic antibacterial therapy application in patients with diabetes mellitus and purulent-necrotic lesions of the foot].
The results of prostaglandin E1 et systemic antibacterial therapy use in 1836 patients, suffering purulent-necrotic affection of foot, were summarized. There was established, that cefuroxym constitutes the first line preparation for the ostheoarthropathy focus elimination, when the affection is limited and the patient state is stable, and meronem--for extended affection and unstable patient's state. In the pronounced ischemia of the foot the initial administration of cefepim is the most effective. For purulent-necrotic affection as a consequence of the foot wounding, erysipelas or operative intervention it is expedient to use carbapenem or meropenem. The systemic antibacterial therapy administration had promoted significant reduction of the treatment duration and improvement of its result.
S Ie
SIe
Podpriatov
O M
OM
Hrabovyĭ
V V
VV
Salata
S V
SV
Zaĭtsev
Z Ie
ZIe
Simonova
S M
SM
Korbut
S Ia
SIa
Shyshova
V P
VP
Rohacheva
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000527:Alprostadil / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D017719:Diabetic Foot / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009336:Necrosis; D016896:Treatment Outcome; D055815:Young Adult
D000900:Anti-Bacterial Agents; D000527:Alprostadil