In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels.
E
E
Belloni
D
D
Shing
C
C
Tapinassi
A
A
Viale
P
P
Mancuso
O
O
Malazzi
E
E
Gerbino
V
V
Dall'Olio
I
I
Egurbide
M D
MD
Odero
F
F
Bertolini
P G
PG
Pelicci
P
P
Giuseppe Pelicci
D000818:Animals; D002471:Cell Transformation, Neoplastic; D050982:GATA1 Transcription Factor / Q000235:genetics* / Q000378:metabolism; D015321:Gene Rearrangement; D007942:Leukemia, Experimental / Q000209:etiology* / Q000473:pathology; D008223:Lymphoma / Q000209:etiology / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D020598:Proto-Oncogene Proteins c-myb / Q000235:genetics* / Q000378:metabolism; D013953:Thymus Neoplasms / Q000209:etiology / Q000473:pathology; D016159:Tumor Suppressor Protein p53 / Q000502:physiology
D050982:GATA1 Transcription Factor; D015514:Oncogene Proteins, Fusion; D020598:Proto-Oncogene Proteins c-myb; D016159:Tumor Suppressor Protein p53