[Progress of osteosarcoma therapy].
OBJECTIVE
To review the research progress of the treatment of osteosarcoma, and to thoroughly understand its current state of research and prospect so as to lay a solid foundation for the clinical treatment.


METHODS
The clinical and experimental research literatures about treatment of osteosarcoma were extensively reviewed and analyzed.


RESULTS
The present treatment of osteosarcoma is still need to comprehensive therapy which combine chemotherapy and surgical treatment. There are some progresses in gene therapy and molecular targeting therapy which can improve survival rate. Furthermore, well-designed studies and clinical trials are needed to evaluate the potential therapeutic impact before they are used in clinical.


CONCLUSIONS
Advancement in chemotherapeutic regimens has improved survival and limb-sparing surgery in the treatment of osteosarcoma, but the progress of gene therapy and molecular targeting therapy gives new hope for osteosarcoma patients.
No.2 Department of Orthopedics, Second Affiliated Hospital of Nanchang University, Nanchang Jiangxi 330006, PR China.
Zhiqiang
Z
Qiu
Qi
Q
Liao
D006801:Humans; D058990:Molecular Targeted Therapy; D012516:Osteosarcoma / Q000188:drug therapy / Q000628:therapy*