[Healthy person's cerebral reactions to the rhythmic transcranial magnetic stimulation of different intensity].
At 8 healthy examinees-volunteers of 22-25 years the functional effects of super-threshold (above 1.2 T) and subthreshold (70-80% of a motor threshold) rTMS of premotor cortexes medial departments were compared. Functional brain activity changes were estimated (before and 1 hour after stimulation) by comparing data including neuropsychological testing, visual and spectral-coherent EEG-analysis, and also haemodynamic parameters. The number of the work's problem included selection of activating orientated stimulation's frequency, and also specification objective EEG--criteria of efficiency rTMS. It is established the effect of EEG-analysis during different frequency photostimulation for a choice of activating rTMS. The received results reveal EEG-coherence as one of the most informative characteristics of cerebral neuro-dynamics under rTMS-influence. Dependence of stimulation's functional effects (activated or brake character) from initial level of the intercentral coherent communications is noted. It is revealed that rTMS of the healthy examinees causes certain changes of functional activity of a brain, distinct from placebo-effects. rTMS-effect dependent on intensity (super--or sub-threshold), and also from features of an initial intercentral rations. More expressed functional changes are observed in the left hemisphere. It is shown big by reactance of the left hemisphere on this influence. In formation of brain responses on rTMS the active role of the vascular factor is shown.
E V
EV
Sharova
V M
VM
Gavrilov
G A
GA
Shechekut'ev
I E
IE
Sokolovskaia
V L
VL
Anzimirov
M V
MV
Korotaeva
D000328:Adult; D058256:Brain Waves / Q000502:physiology*; D054022:Cerebrum / Q000502:physiology*; D006801:Humans; D008297:Male; D050781:Transcranial Magnetic Stimulation / Q000379:methods*