Acellular dermal matrix in the treatment and prevention of exposed vertical expandable prosthetic titanium ribs.
METHODS
Case series.


OBJECTIVE
To illustrate the use of acellular dermal matrix (ADM) in treatment and prevention of exposed vertical expandable prosthetic titanium rib (VEPTR) implants.


BACKGROUND
In the pediatric population with severe kyphoscoliosis, VEPTR is an effective tool during growth for the correction of ribcage deformity. Prolonged VEPTR therapy can result in wound breakdown, implant exposure, and infection. Treatment includes the use of prolonged antibiotics, muscle flaps, and, when salvage fails, removal of the VEPTR. The use of ADM in the treatment and prevention of VEPTR exposure has not been previously described.


METHODS
Between January 2002 and January 2010, eight patients who underwent placement of ADM for the treatment and prevention of exposed VEPTR devices were identified. Their records were reviewed for diagnosis, sex, age of patient at initial VEPTR placement, position of VEPTR placement, number of VEPTR expansions, wound complications, ADM use, adjunct procedures, and length of wound follow-up.


RESULTS
ADM was used in eight patients. In five patients ADM was used for compromised soft tissue overlying the VEPTR and threatened exposure of the hardware. In these cases, subsequent expansions occurred without incident and the wound remained stable with an average follow-up of 7.6 months. In three patients, ADM was used for exposed VEPTR hardware secondary to wound breakdown. Average follow-up was 3.3 months. In two of the three cases of exposed and contaminated hardware, stable soft tissue coverage was achieved and continued VEPTR therapy was achieved. One of the three cases of exposure involved infected and prominent hardware with purulence. This patient failed to clear the infection and required complete device removal.


CONCLUSIONS
ADM can treat and prevent exposed VEPTR, allowing subsequent VEPTR expansions and minimizing the need for muscle flap coverage and/or implant removal and replacement.
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA.
Roop
R
Gill
Christopher R
CR
Kinsella
Alexander Y
AY
Lin
Lorelei J
LJ
Grunwaldt
Shao
S
Jiang
Vincent F
VF
Deeney
Joseph
J
Losee
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000601:surgery; D008297:Male; D019736:Prostheses and Implants; D012272:Ribs / Q000601:surgery; D012600:Scoliosis / Q000601:surgery; D016038:Skin Transplantation / Q000379:methods; D017768:Skin, Artificial; D014025:Titanium; D016896:Treatment Outcome; D014945:Wound Healing
D014025:Titanium