A proposed nomenclature for cell wall proteins of Clostridium difficile.
Strains of Clostridium difficile produce a number of surface-localized proteins, including the S-layer proteins (SLPs) and other proteins that have suspected roles in pathogenesis. During the Third International C. difficile Symposium (Bled, Slovenia, September 2010) discussions were held on standardization of nomenclature. Gene designations were proposed for the large family of cell wall proteins that are paralogues of the SLP and contain putative cell wall binding motifs. This paper summarizes the agreed nomenclature, which we hope will be used by research groups currently active in the field.
Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London SW7 2AZ, UK.
Robert P
RP
Fagan
Université de Paris-Sud XI, USC INRA EA 4043, Faculté de Pharmacie, Châtenay-Malabry Cedex, France.
Claire
C
Janoir
Université de Paris-Sud XI, USC INRA EA 4043, Faculté de Pharmacie, Châtenay-Malabry Cedex, France.
Anne
A
Collignon
Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Paola
P
Mastrantonio
Medical Microbiology, Centre for Infectious Diseases, University of Edinburgh College of Medicine and Veterinary Medicine, Edinburgh EH16 4SB, UK.
Ian R
IR
Poxton
Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London SW7 2AZ, UK.
Neil F
NF
Fairweather
D001426:Bacterial Proteins / Q000145:classification* / Q000378:metabolism; D002473:Cell Wall / Q000378:metabolism*; D016360:Clostridioides difficile / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology; D016680:Genome, Bacterial; D005810:Multigene Family; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D009626:Terminology as Topic
D001426:Bacterial Proteins