Modulation of reflex responses in activated ankle dorsiflexors differs in healthy young and elderly subjects.
During voluntary contractions, motor neurone activity is modulated by descending input and sensory feedback. Impaired excitatory afferent feedback with ageing may, therefore, alter motor control. This study investigated the age-related changes in afferent feedback through the recording of reflex responses during voluntary muscle activation. Short- and long-latency components of the stretch reflex and Hoffmann reflex (H-reflex) were recorded during voluntary contractions (10% of maximal voluntary contraction; MVC) of the ankle dorsiflexor muscles of young and elderly adults (≥70 years). Furthermore, the modulation of spinal reflex excitability was analyzed at different torque levels (10-50% MVC). The short-latency stretch reflex and the H-reflex areas were similar in the two age groups at 10% MVC whereas the area of the long-latency component of the stretch reflex augmented with ageing (P < 0.05). However, the area of the H-reflex increased linearly with the level of contraction up to 50% MVC in young adults, whereas it slightly increased to 30% MVC and plateaued thereafter in elderly adults. The absence of age-related changes in the short-latency stretch reflex and H-reflex areas suggests that the reflex circuitry and the sensitivity of the muscle spindles are not substantially affected by ageing. The modest increase in the H-reflex area with the contraction intensity in elderly adults, however, indicates that the modulation of afferent feedback is reduced with advancing age. This observation, associated with a greater long-latency stretch reflex, suggests that elderly adults rely more on central than peripheral mechanisms to regulate motor output of the dorsiflexor muscles.
Laboratory of Applied Biology, Faculté des Sciences de la Motricité, Université Libre de Bruxelles, 808 route de Lennik, CP 640, 1070, Brussels, Belgium. mklass@ulb.ac.be
Malgorzata
M
Klass
Stéphane
S
Baudry
Jacques
J
Duchateau
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000843:Ankle Joint / Q000502:physiology*; D005260:Female; D006181:H-Reflex / Q000502:physiology; D006262:Health; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D011187:Posture / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012026:Reflex, Stretch / Q000502:physiology*; D019415:Torque; D055815:Young Adult
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