Shock: a common consequence of neonatal asphyxia.
Neonatal asphyxia is associated with multi-organ hypoxia-ischemia and subsequent dysfunction. The cardiovascular system is frequently affected, causing signs of shock and complicating the neonatal circulatory transition. Hypothermia therapy can improve outcome from neonatal asphyxia without adversely affecting cardiovascular stability. Therapy directed at the cardiovascular system can improve short-term measures of systemic blood flow, but to date has not been demonstrated to improve long-term outcome.
Department of Pediatrics, University of California, San Diego, CA 92103, USA. tleone@ucsd.edu
Tina A
TA
Leone
Neil N
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Finer
D001238:Asphyxia Neonatorum / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D001831:Body Temperature; D002319:Cardiovascular System / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods; D020925:Hypoxia-Ischemia, Brain / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D007231:Infant, Newborn; D008297:Male; D012769:Shock / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome