Successful on-pump coronary artery bypass without using protamine.
A 48-year-old woman presented with a history of angina and breathlessness on exertion. She was diagnosed to have critical left main stem coronary artery disease along with a blocked right coronary artery. She was also allergic to protamine. After multidisciplinary consultation, it was decided to use heparin without protamine for reversal. She underwent successful on-pump coronary artery bypass grafting (CABG) without excessive blood loss. The disadvantages were a longer total operating time and the use of blood products to achieve normal coagulation. This case report describes the successful management of this complex problem.
Department of Cardiothoracic Surgery, Victoria Hospital, Blackpool, United Kingdom.
Vivek
V
Srivastava
Palanikumar
P
Saravanan
Jeanette
J
Abraham
John
J
Au
D000075202:Contraindications; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D011479:Protamines
D011479:Protamines; D006493:Heparin