Psyllium allergy in hospital personnel: a report on twelve patients.
We have followed 12 patients with acute symptoms on exposure to psyllium over a three-year period. All were hospital personnel with evidence of atopy. Exposure was by inhalation on dispensing psyllium powder. Symptoms which occurred within minutes of exposure included rhinitis (12/12), conjunctivitis (10/12), shortness of breath and wheezing (9/12). All patients had psyllium-specific IgE antibodies demonstrated by either positive prick-skin tests (1:100) or serum antibodies (rast). Controls had no reactivity to psyllium. Sensitivity persisted over the entire three-year period. We conclude that sensitivity to psyllium is an IgE-mediated occupational allergy in hospital personnel; that it produces significant symptoms and it is often unrecognized; and that persistance of sensitivity necessitates strict avoidance of psyllium by all routes of exposure.
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Jancelewicz
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Dolovich
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GL
Sussman
Allergy. 1985 Jan;40(1):73-6
3156543
Allergy. 1983 Jul;38(5):363-5
6614409
Med Ann Dist Columbia. 1970 Jun;39(6):313 passim
5270280
Ann Intern Med. 1975 Sep;83(3):361-2
1180433
Am Rev Respir Dis. 1986 Apr;133(4):686-703
3516040
Biochemistry. 1967 Jul;6(7):1992-2000
4167436
J Allergy Clin Immunol. 1971 Oct;48(4):200-11
5285772
JAMA. 1979 Apr 13;241(15):1573-4
430704
Ann Allergy. 1982 May;48(5):294-8
7081783
Ann Allergy. 1979 Mar;42(3):145-7
426323
Allergy. 1979 Feb;34(1):51-5
453486
J Allergy Clin Immunol. 1984 Jul;74(1):79-80
6736485
Allergy. 1984 Jan;39(1):65-8
6696210
Clin Allergy. 1974 Sep;4(3):273-80
4214634