Lipoxins: a novel regulator in embryo implantation.
Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity, including leukemia inhibitory factor, calcitonin, and homeobox A10. There is a close relationship between implantation and inflammation. Lipoxins, important in the resolution of inflammation, may be a potential regulator in implantation. Here we discuss the hypothesis that lipoxins may work as a novel regulator in embryo implantation and the possible molecular mechanisms.
Institute of Pathology, Tongji Hospital, and Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China.
Jing
J
Xiong
Pan
P
Zeng
Duyun
D
Ye
D000818:Animals; D002116:Calcitonin / Q000378:metabolism; D010064:Embryo Implantation / Q000276:immunology*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D053605:Leukemia Inhibitory Factor / Q000378:metabolism; D044045:Lipoxins / Q000378:metabolism*; D011247:Pregnancy
D053605:Leukemia Inhibitory Factor; D044045:Lipoxins; D002116:Calcitonin