Nonmetal catalyzed insertion reactions of diazocarbonyls to acid derivatives in fluorinated alcohols.
The insertion reaction of diazocarbonyls to acids could be performed smoothly in fluorinated alcohols in the absence of metal catalyst. This new procedure allowed the chemoselective preparation of various functionalized compounds such as acyloxyesters, depsipeptides, and sulfonate, phosphonate, or boronate derivatives.
Laboratoire BioCIS-CNRS, Faculté de Pharmacie, Univ. Paris-Sud, rue J. B. Clément, F-92296 Châtenay-Malabry, France.
Lidia
L
Dumitrescu
Kaouther
K
Azzouzi-Zriba
Danièle
D
Bonnet-Delpon
Benoit
B
Crousse
D000438:Alcohols / Q000737:chemistry*; D000476:Alkanesulfonates / Q000138:chemical synthesis / Q000737:chemistry; D001897:Boronic Acids / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003979:Diazonium Compounds / Q000737:chemistry*; D054879:Halogenation; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010755:Organophosphates / Q000138:chemical synthesis / Q000737:chemistry
D000438:Alcohols; D000476:Alkanesulfonates; D001897:Boronic Acids; D003979:Diazonium Compounds; D007659:Ketones; D010755:Organophosphates; C032111:diazoacetic ester