Disruption of reverse micelles and release of trapped ribonuclease A photochemically induced by Malachite Green leuconitrile derivative.
Photoinduced disruption of a sodium bis(2-ethylhexyl) sulfosuccinate (AOT) reverse micelle is triggered by a Malachite Green leuconitrile derivative (MGL). UV irradiation of MGL solubilized in an AOT-water-chloroform mixture creates a cationic surfactant that interacts electrostatically with the anionic AOT. We investigated the disruption of the reverse micelle by using proton nuclear magnetic resonance spectroscopy and found that UV irradiation of MGL decreases the number of water molecules solubilized in the interior of the AOT reverse micelles. Furthermore, the photoinduced disruption of the reverse micelle is shown to release ribonuclease A, which is trapped in the water in the interior of the AOT reverse micelle. This photoinduced release may offer a desirable transport system of biopolymers.
Department of Chemical Engineering, Nara National College of Technology, Yata 22, Yamato-koriyama, Nara 639-1080, Japan. ryoko@chem.nara.-k.ac.jp
Ryoko M
RM
Uda
Tsuyoshi
T
Nishikawa
Yoshitsugu
Y
Morita
D004143:Dioctyl Sulfosuccinic Acid / Q000737:chemistry* / Q000378:metabolism; D004337:Drug Carriers / Q000737:chemistry; D007477:Ions; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D009570:Nitriles / Q000737:chemistry; D012260:Ribonucleases / Q000737:chemistry / Q000378:metabolism; D012394:Rosaniline Dyes / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism; D014466:Ultraviolet Rays; D014867:Water / Q000737:chemistry
D004337:Drug Carriers; D007477:Ions; D008823:Micelles; D009570:Nitriles; D012394:Rosaniline Dyes; D014867:Water; D004143:Dioctyl Sulfosuccinic Acid; C005095:malachite green; D012260:Ribonucleases