Assembly of folate-polyoxometalate hybrid spheres for colorimetric immunoassay like oxidase.
Folate-functionalized polyoxometalate nanoparticles have unique oxidase-like activity, which can facilitate the fast oxidation of organic dyes without using any oxidizing agents or peroxidases especially at neutral pH conditions. This nanoparticle could be used as an agent in colorimetric multiplexed immunoassays.
Key Laboratory of Polyoxometalates, Science of Ministry of Education, Faculty of Chemistry, Northeast Normal University, Changchun, 130024, P.R. China.
Jingjing
J
Wang
Xuguang
X
Mi
Hongyu
H
Guan
Xiaohong
X
Wang
Yin
Y
Wu
D001560:Benzidines / Q000737:chemistry; D040761:Biomimetic Materials / Q000737:chemistry*; D003124:Colorimetry / Q000379:methods*; D005492:Folic Acid / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007118:Immunoassay / Q000379:methods*; D008958:Models, Molecular; D008968:Molecular Conformation; D008982:Molybdenum / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D014639:Vanadium / Q000737:chemistry*
D001560:Benzidines; D014639:Vanadium; C021758:3,3',5,5'-tetramethylbenzidine; D008982:Molybdenum; D005492:Folic Acid; D010088:Oxidoreductases