Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease.
Edwardsiella tarda, a catalase-positive bacillus widely distributed throughout nature, is generally susceptible to trimethoprim/sulfamethoxazole. We describe osteomyelitis due to trimethoprim/sulfamethoxazole-resistant E. tarda in a patient with chronic granulomatous disease (CGD). Once E. tarda acquires antibiotic resistance, infected CGD patients may develop severe infections with unforeseeable consequences.
Department of Human Genetics, National Center for Child Health and Development, Tokyo, Japan. kawai-t@ncchd.go.jp
T
T
Kawai
H
H
Kusakabe
A
A
Seki
S
S
Kobayashi
M
M
Onodera
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D020609:Edwardsiella tarda / Q000187:drug effects / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007866:Leg / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010019:Osteomyelitis / Q000382:microbiology* / Q000473:pathology; D011859:Radiography; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
Eur J Pediatr. 2008 Dec;167(12):1389-94
18335239
Clin Infect Dis. 1993 Oct;17(4):742-8
8268359
Clin Immunol. 2008 Feb;126(2):155-64
18037347
Clin Rev Allergy Immunol. 2010 Feb;38(1):3-10
19504359
Infection. 2010 Dec;38(6):487-9
20931258
J Antimicrob Chemother. 2006 Feb;57(2):204-11
16390858
BMC Microbiol. 2006 Jul 20;6:66
16857052
Am J Clin Pathol. 1968 Jan;49(1):92-5
5635280
Clin Infect Dis. 2009 Aug 15;49(4):606-11
19591599
Infection. 2009 Oct;37(5):469-73
19669090
Ann Intern Med. 1969 Feb;70(2):283-8
5764505
Clin Infect Dis. 2001 Jun 1;32(11):1608-14
11340533