A case of sepsis and meningitis caused by probable travel-related Neisseria meningitidis serogroup B infection: the first report of N. meningitidis ST-4893 in Japan.
Herein we present a case of Neisseria meningitidis-related sepsis and meningitis in a 60-year-old woman. The N. meningitidis strain was identified as serogroup B and sequence type (ST)-4893 by multilocus sequence typing (MLST). The patient in this case had visited France prior to development of symptoms. No meningococcal isolate belonging to ST-4893 has been identified in Japan previously, whereas an ST-4893 strain from France has been reported in the MLST database. These results strongly suggest that this case is likely to have been imported from France.
Department of Clinical Laboratory, Fujita Health University Hospital, Aichi 470-1192, Japan. a-naka@fujita-hu.ac.jp
Asami
A
Nakayama
Hideyuki
H
Takahashi
Kiyofumi
K
Ohkusa
Katsuo
K
Yamanaka
Chiyo
C
Shintani
Satoshi
S
Hayakawa
Junichi
J
Ishii
Haruo
H
Watanabe
D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D005602:France; D006801:Humans; D007564:Japan; D008585:Meningitis, Meningococcal / Q000382:microbiology*; D008589:Meningococcal Infections / Q000382:microbiology; D008875:Middle Aged; D038541:Neisseria meningitidis, Serogroup B / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D018805:Sepsis / Q000382:microbiology*; D017422:Sequence Analysis, DNA / Q000379:methods; D014195:Travel
D001426:Bacterial Proteins; D004269:DNA, Bacterial