Climate change, aeroallergens, and pediatric allergic disease.
The degree to which aeroallergens are contributing to the global increase in pediatric allergic disease is incompletely understood. We review the evidence that links climate change to changes in aeroallergens such as pollen and outdoor mold concentrations and, subsequently, aeroallergen association with pediatric allergic disease. We specifically explore the evidence on both the exacerbation and the development of allergic disease in children related to outdoor pollen and mold concentrations. Pediatric allergic diseases include atopic dermatitis or eczema, allergic rhinitis or hay fever, and some types of asthma in children, typically defined as < 18 years of age. We discuss how the timing of aeroallergen exposure both in utero and in childhood could be associated with allergies. We conclude that the magnitude and type of health impacts due to climate change will depend on improved understanding of the relationship between climatic variables, multiple allergen factors, and allergic disease. Improved public-health strategies such as adequate humidity control, optimum air filtration and ventilation, and improved anticipatory public-health messaging will be critical to adaptation.
Departments of Pediatrics and Preventive Medicine, Mount Sinai School of Medicine, New York, NY, USA. perry.sheffield@mssm.edu
Perry E
PE
Sheffield
Kate R
KR
Weinberger
Patrick L
PL
Kinney
D000393:Air Pollutants / Q000009:adverse effects*; D000485:Allergens / Q000009:adverse effects*; D002648:Child; D057231:Climate Change; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*
D000393:Air Pollutants; D000485:Allergens
Curr Allergy Asthma Rep. 2008 Sep;8(5):418-24
18682110
Environ Health Perspect. 2000 Jun;108 Suppl 3:475-82
10852847
J Allergy Clin Immunol. 1976 Jun;57(6):609-14
932344
Allergy Asthma Proc. 2009 May-Jun;30(3):229-37
19549423
Clin Exp Allergy. 2009 Jul;39(7):991-8
19302247
Allergy. 2003 Sep;58(9):871-7
12911415
Clin Exp Allergy. 2006 Dec;36(12):1488-93
17177671
Ann Allergy Asthma Immunol. 2002 Mar;88(3):279-82
11926621
Environ Health Perspect. 2001 May;109 Suppl 2:199-209
11359687
J Allergy Clin Immunol. 2009 May;123(5):1041-6
19361844
Environ Health Perspect. 2000 Jun;108 Suppl 3:483-90
10852848
Allergy. 1998 Mar;53(3):266-74
9542606
Environ Res. 2008 Feb;106(2):203-11
18093580
J Asthma. 2007 May;44(4):257-60
17530522
Allergy Asthma Proc. 2001 Jul-Aug;22(4):239-47
11552675
Pediatr Allergy Immunol. 2004 Jun;15 Suppl 16:4-5, 9-32
15125698
Ann Allergy Asthma Immunol. 2001 Nov;87(5):394-404
11730182
J Allergy Clin Immunol. 2002 Jul;110(1):78-84
12110825
Int J Biometeorol. 1997 Jul;41(1):17-22
9334570
Pediatr Allergy Immunol. 2009 Sep;20(6):536-44
19175891
Int J Biometeorol. 2002 Sep;46(4):159-70
12242471
Int J Biometeorol. 2001 Jul;45(2):64-74
11513049
J Allergy Clin Immunol. 2010 Mar;125(3):575-81
20226293
Annu Rev Public Health. 2010;31:165-78 1 p following 178
20070193
Funct Plant Biol. 2005 Aug;32(7):667-670
32689165
Thorax. 2009 Apr;64(4):353-8
19240083
Pediatr Allergy Immunol. 2009 Feb;20(1):12-8
18298422
Allergy. 2003 Jul;58(7):572-9
12823113
Pediatr Pulmonol. 2006 Dec;41(12):1125-8
17034060
Nature. 2003 Jan 2;421(6918):37-42
12511946
Pediatr Allergy Immunol. 2004 Dec;15(6):497-505
15610362
Int J Environ Res Public Health. 2010 Feb;7(2):675-97
20616997
Hum Exp Toxicol. 2002 Sep-Oct;21(9-10):499-505
12458907
Environ Health. 2010 Aug 02;9:46
20678227