Medical management of Trichophyton dermatophytosis using a novel treatment regimen in L'Hoest's monkeys (Cercopithecus lhoesti).
An outbreak of Trichophyton dermatophytosis was diagnosed in a group of four L'Hoest's monkeys (Cercopithecus lhoesti) housed in the primate section at a zoological collection. The affected animals presented with areas of non-pruritic alopecia, scaling and crusting. The diagnosis was based on culture and direct microscopy of hair plucks. Treatment was commenced with oral terbinafine at a dose of 8.25 mg/kg bodyweight, topical enilconazole washes and disinfectant fogging of the enclosure. Control measures were designed to limit the spread of infection and reduce the zoonotic risk. Treatment was successful, with no further clinical cases being diagnosed and with resolution of the clinical signs after four weeks and mycological cure after eight weeks.
Exotic Animal and Wildlife Service, Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian. ekeeble@vet.ed.ac.uk
E J
EJ
Keeble
A
A
Neuber
L
L
Hume
G
G
Goodman
D000284:Administration, Oral; D000287:Administration, Topical; D000818:Animals; D000836:Animals, Zoo; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002521:Cercopithecus; D004196:Disease Outbreaks / Q000662:veterinary; D004359:Drug Therapy, Combination / Q000662:veterinary; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008992:Monkey Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000635:transmission; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use*; D000077291:Terbinafine; D014005:Tinea / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission / Q000662:veterinary*; D016896:Treatment Outcome; D015047:Zoonoses
D000935:Antifungal Agents; D007093:Imidazoles; D009281:Naphthalenes; C017435:enilconazole; D000077291:Terbinafine