Glycemic index and pregnancy: a systematic literature review.
Background/Aim. Dietary glycemic index (GI) has received considerable research interest over the past 25 years although its application to pregnancy outcomes is more recent. This paper critically evaluates the current evidence regarding the effect of dietary GI on maternal and fetal nutrition. Methods. A systematic literature search using MEDLINE, EMBASE, CINAHL, Cochrane Library, SCOPUS, and ISI Web of Science, from 1980 through September 2010, was conducted. Results. Eight studies were included in the systematic review. Two interventional studies suggest that a low-GI diet can reduce the risk of large-for-gestational-age (LGA) infants in healthy pregnancies, but one epidemiological study reported an increase in small-for-gestational-age (SGA) infants. Evidence in pregnancies complicated by gestational diabetes mellitus (GDM), though limited (n = 3), consistently supports the advantages of a low-GI diet. Conclusion. There is insufficient evidence to recommend a low-GI diet during normal pregnancy. In pregnancy complicated by GDM, a low-GI diet may reduce the need for insulin without adverse effects on pregnancy outcomes. Until larger-scale intervention trials are completed, a low-GI diet should not replace the current recommended pregnancy diets from government and health agencies. Further research regarding the optimal time to start a low-GI diet for maximum protection against adverse pregnancy outcomes is warranted.
Discipline of Nutrition and Metabolism, School of Molecular Bioscience, The University of Sydney, Sydney, NSW 2006, Australia.
Jimmy Chun Yu
JC
Louie
Jennie C
JC
Brand-Miller
Tania P
TP
Markovic
Glynis P
GP
Ross
Robert G
RG
Moses
N Engl J Med. 2005 Jun 16;352(24):2477-86
15951574
Eur J Clin Nutr. 2009 Jul;63(7):872-8
18957972
Arch Intern Med. 2010 Apr 12;170(7):640-7
20386010
Diabetes Care. 2010 Mar;33(3):676-82
20190296
Diabetes. 1991 Dec;40 Suppl 2:126-30
1748241
Am J Clin Nutr. 2008 Sep;88(3):693-9
18779285
Obstet Gynecol Surv. 2007 Feb;62(2):125-36
17229329
BMJ. 2002 Aug 17;325(7360):359
12183306
Am J Epidemiol. 1996 Sep 15;144(6):563-9
8797516
Diabetes Care. 2008 Jan;31 Suppl 1:S61-78
18165339
Semin Fetal Neonatal Med. 2010 Apr;15(2):113-8
19853544
Am J Epidemiol. 2004 Mar 1;159(5):467-74
14977642
N Engl J Med. 2009 Oct 1;361(14):1339-48
19797280
N Engl J Med. 2008 May 8;358(19):1991-2002
18463375
Proc Nutr Soc. 2002 Feb;61(1):45-50
12008645
Diabetes Care. 2006 Oct;29(10):2223-30
17003297
Cochrane Database Syst Rev. 2003;(4):CD000032
14583907
Am J Clin Nutr. 2010 Jun;91(6):1764-8
20375186
Obstet Gynecol. 1998 Apr;91(4):600-4
9540949
Am J Obstet Gynecol. 1998 Jun;178(6):1321-32
9662318
Int J Obes Relat Metab Disord. 2001 May;25(5):735-40
11360158
Am J Obstet Gynecol. 2010 Jun;202(6):574.e1-8
20132923
J Am Diet Assoc. 2001 Aug;101(8):897-902
11501863
Arch Pediatr Adolesc Med. 1998 Dec;152(12):1225-31
9856434
J Am Diet Assoc. 2008 Mar;108(3):553-61
18401922
Paediatr Perinat Epidemiol. 2008 Jan;22(1):47-59
18173784
Diabetes Care. 2007 Sep;30(9):2287-92
17519427
Obstet Gynecol. 2008 Nov;112(5):1007-14
18978099
J Pediatr. 2002 Oct;141(4):538-42
12378194
Am J Clin Nutr. 2007 Dec;86(6):1806
18065603
N Engl J Med. 1995 Nov 9;333(19):1237-41
7565999
J Am Coll Nutr. 2008 Jun;27(3):387-93
18838526
Womens Health (Lond). 2008 Nov;4(6):639-56
19072465
Am J Clin Nutr. 2006 Oct;84(4):807-12
17023707
Am J Obstet Gynecol. 2009 Jul;201(1):51.e1-6
19576373
Diabetes Care. 2008 Jan;31(1):e1
18165345
Am J Clin Nutr. 2006 Jul;84(1):70-6; quiz 266-7
16825683
Nutr J. 2006 Sep 05;5:22
16953881
Am J Clin Nutr. 2009 Jan;89(1):97-105
19056599
JAMA. 2004 Aug 18;292(7):789-90
15315980
Diabetes Care. 2009 Jun;32(6):996-1000
19279301
Int J Obes Relat Metab Disord. 2003 Jul;27(7):755-77
12821960
Cochrane Database Syst Rev. 2008 Apr 16;(2):CD006674
18425961
Obstet Gynecol. 2006 Sep;108(3 Pt 1):635-43
16946225
Am J Epidemiol. 2001 Sep 15;154(6):514-20
11549556
BMJ. 2005 Jun 11;330(7504):1357
15908441