A Critical Look at HIV-Antibody Tests: 1. How Accurate Are They?
As the AIDS epidemic spreads, many patients are asking their primary-care physicians to perform AIDS (HIV-antibody) testing, and in some settings, clinical circumstances prompt physicians to consider ordering the test. As a result, thousands of HIV-antibody tests are being requested each month by Canadian family doctors, where none were available only two years ago. Yet particular characteristics of HIV infection make these tests very unlike most blood tests, since their use carries clear risks as well as benefits. The authors review these risks and benefits in two sequential articles. In this first paper, they review the quantitative aspects of test accuracy (validity). In a sequential paper, to be published in next month's issue, they will discuss the risks and benefits of performing the test in various clinical circumstances.
J W
JW
Frank
V
V
Goel
B J
BJ
Harvey
R A
RA
Coates
V
V
Schiralli
JAMA. 1986 May 2;255(17):2299-305
3007791
Lancet. 1986 Oct 18;2(8512):921-2
2876354
Can Fam Physician. 1987 May;33:1209-13
21263930
J Chronic Dis. 1986;39(12):1125-44
3539971
Transfusion. 1986 Nov-Dec;26(6):539-41
3535180
N Engl J Med. 1986 Mar 6;314(10):647-8
3511375
Can Fam Physician. 1987 May;33:1223-7
21263932
JAMA. 1987 Feb 27;257(8):1047
3027425
N Engl J Med. 1987 Jul 23;317(4):238-41
3474520
JAMA. 1986 Jul 18;256(3):357-61
3014173
Ann Intern Med. 1985 Nov;103(5):700-3
2996402
Science. 1986 May 9;232(4751):697
3008335
MMWR Morb Mortal Wkly Rep. 1985 Sep 6;34(35):547-8
3927147
JAMA. 1986 Jul 18;256(3):347
3459899
Blood. 1985 Sep;66(3):742-4
2992644
JAMA. 1985 Jun 21;253(23):3405-8
2987558
Ann Intern Med. 1985 Nov;103(5):726-9
2996408
Lancet. 1987 May 23;1(8543):1164-8
2883489
Ann Intern Med. 1986 Oct;105(4):609-10
3019204
Lancet. 1986 Nov 29;2(8518):1233-6
2878129
Am J Clin Pathol. 1986 Aug;86(2):180-5
3017089
J Infect Dis. 1987 Mar;155(3):558-60
3468176
J Infect Dis. 1986 Apr;153(4):736-42
3005434
JAMA. 1985 Jan 11;253(2):221-5
2981369
N Engl J Med. 1986 Dec 11;315(24):1549
3466032
N Engl J Med. 1986 Jan 2;314(1):1-6
3484393
Isr J Med Sci. 1986 Jul-Aug;22(7-8):524-8
3640749