Passive case-finding for Alzheimer's disease and dementia in two U.S. communities.
Passive surveillance for disease is a public health approach that relies on documentation available within existing health records for the region or community being studied. Its two primary advantages over active case-finding are the lower cost of research and the lower burden on the population under study. The effectiveness of passive case-finding depends on the comprehensiveness of the healthcare coverage in a given community and the adequacy of the available medical records. The Rochester Epidemiology Project has permitted dementia case detection for Olmsted County, Minnesota, using a medical records-linkage system. These data were compared with case ascertainment using direct assessment of individuals in an epidemiological study of the same community. At the Group Health Research Institute, investigators compared dementia and Alzheimer's disease cases detected using an electronic medical record database search with those identified by a parallel active case-finding study. In this article, the advantages and disadvantages of passive case-finding were discussed, and the following conclusion was drawn: the purpose of the study being conducted should determine the case-finding approach that is to be used.
Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN, USA. knopman@mayo.edu
David S
DS
Knopman
Ronald C
RC
Petersen
Walter A
WA
Rocca
Eric B
EB
Larson
Mary
M
Ganguli
D000367:Age Factors; D000544:Alzheimer Disease / Q000453:epidemiology*; D003704:Dementia / Q000453:epidemiology*; D006306:Health Surveys; D006801:Humans; D008498:Medical Record Linkage; D008910:Minnesota / Q000453:epidemiology; D015995:Prevalence; D015203:Reproducibility of Results; D012111:Residence Characteristics; D012737:Sex Factors; D014861:Washington / Q000453:epidemiology
Arch Neurol. 2002 Oct;59(10):1589-93
12374497
Science. 1987 Oct 23;238(4826):539-42
3659926
Neurology. 1995 Jan;45(1):75-9
7824140
J Am Geriatr Soc. 2000 Nov;48(11):1430-4
11083319
Am J Epidemiol. 1998 Jul 1;148(1):51-62
9663404
Neurology. 2010 Sep 7;75(10):889-97
20820000
Arch Neurol. 2006 Feb;63(2):218-21
16476810
JAMA. 1997 Mar 12;277(10):800-5
9052709
Arch Intern Med. 2000 Oct 23;160(19):2964-8
11041904
J Alzheimers Dis. 2006;9(3 Suppl):409-15
16914879
Neuroepidemiology. 2010;34(1):34-42
19893327
Aging (Milano). 1990 Dec;2(4):404-8
2094380
J Am Geriatr Soc. 1996 Jun;44(6):704-7
8642164
J Am Geriatr Soc. 2004 Oct;52(10):1668-75
15450043
Ann Intern Med. 1995 Mar 15;122(6):422-9
7856990
J Geriatr Psychiatry Neurol. 1995 Oct;8(4):203-8
8561832
Neurology. 1989 Jun;39(6):773-6
2725870
J Alzheimers Dis. 2009;18(3):643-4
19625745
Neuroepidemiology. 2009;32(3):229-39
19176974
Neuroepidemiology. 2008;30(1):58-69
18259084
Psychol Med. 1996 Nov;26(6):1223-30
8931168
Mayo Clin Proc. 1996 Mar;71(3):266-74
8594285
Alzheimer Dis Assoc Disord. 2005 Apr-Jun;19(2):67-73
15942323
JAMA. 2009 Apr 15;301(15):1565-72
19366776
Mayo Clin Proc. 1999 Apr;74(4):330-8
10221460
J Am Geriatr Soc. 1981 Dec;29(12):579-82
7310042
Ann Intern Med. 1984 Mar;100(3):417-23
6696360
Biol Psychiatry. 1988 Dec;24(8):925-36
3266076
J Am Geriatr Soc. 2000 Mar;48(3):300-4
10733057
Neurology. 1993 Nov;43(11):2412-4
8232972
J Gerontol A Biol Sci Med Sci. 1998 Jul;53(4):M313-9
18314572