Tn2008 is a major vehicle carrying bla(OXA-23) in Acinetobacter baumannii from China.
bla(OXA-23) and bla(OXA-66) were detected in 49 Acinetobacter baumannii isolates. These isolates were assigned to 7 subtypes by enterobacterial repetitive intergenic consensus polymerase chain reaction and 7 representative isolates were of ST92 or ST75. In most cases, the ISAba1-bla(OXA-23)-ATPaseΔ structure was identical to Tn2008. The 16-bp sequence at the left end of Tn2008 resembled the inverted repeat of ISAba1, suggesting that ISAba1 might have utilized an alternative boundary to mobilize bla(OXA-23).
Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiaohui
X
Wang
Zhiyong
Z
Zong
Xiaoju
X
Lü
D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D015373:Bacterial Typing Techniques; D001483:Base Sequence; D002681:China; D005798:Genes, Bacterial; D006801:Humans; D054643:INDEL Mutation; D058885:Multilocus Sequence Typing; D010802:Phylogeny; D001618:beta-Lactamases / Q000235:genetics*
D001618:beta-Lactamases