title: [Leiomyosarcoma of the kidney with tumor thrombus to the inferior vena cava].
abstract: A 76-year-old female presented with edema in the bilateral lower legs and computed tomography (CT) subsequently revealed a tumor under the right side of the kidney that extended to the inferior vena cava. Under suspicion of a right renal sarcoma or malignant teratoma, we performed a right nephrectomy and tumor thrombectomy. Histopathological features of the resected specimen were compatible with a leiomyosarcoma originating from either extrarenal blood vessels or muscle fibers of the renal pelvis. Immunohistological findings showed that the tumor cells were spindle-shaped, arranged in bundles, and stained positive for α-smooth muscle actin and desmin. The patient was free from recurrence 10 months after surgery. The prognosis of patients with a renal leiomyosarcoma with venous thrombus has been considered to be poor. Herein, we provide details of our case and conclude that radical tumor resection is necessary for a long-term cure.
authors.affiliation: The Department of Specific Organ Regulation, Osaka University Graduate School of Medicine.
authors.forename: Taigo
authors.initials: T
authors.lastname: Kato
authors.forename: Yasutomo
authors.initials: Y
authors.lastname: Nakai
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Miyagawa
authors.forename: Yuka
authors.initials: Y
authors.lastname: Uesaka
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Takao
authors.forename: Norio
authors.initials: N
authors.lastname: Nonomura
authors.forename: Akihiko
authors.initials: A
authors.lastname: Okuyama
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D014682:Vena Cava, Inferior / Q000473:pathology*; D020246:Venous Thrombosis / Q000473:pathology*