title: Paediatric HIV and elimination of mother-to-child transmission of HIV in the ASEAN region: a call to action.
abstract: Recent achievements in scaling up paediatric antiretroviral therapy (ART) have changed the life of children living with HIV, who now stay healthy and live longer lives. However, as it becomes more of a chronic infection, a range of new problems have begun to arise. These include the disclosure of HIV serostatus to children, adherence to ART, long-term toxicities of antiretroviral drugs and their sexual and reproductive health, which are posing significant challenges to the existing health systems caring for children with HIV with limited resources, experiences and capacities. While intensified efforts and actions to improve care and treatment for these children are needed, it is crucial to accelerate the prevention of mother-to-child transmission (PMTCT) of HIV, which is the main cause of paediatric HIV in the ASEAN region so as to eliminate the fundamental cause of the problem. This report argues that given over 70% of women have access to at least one antenatal care visit in the region and acceptance of HIV testing after receiving counselling on PMTCT could be as high as 90%, there is an opportunity to strengthen PMTCT services and eventually eliminate new paediatric HIV infections in the ASEAN countries.
authors.affiliation: The Bureau of International Medical Cooperation, National Center for Global Health and Medicine, Tokyo, Japan. n-ishikawa@it.ncgm.go.jp
authors.forename: Naoko
authors.initials: N
authors.lastname: Ishikawa
authors.forename: Kyoko
authors.initials: K
authors.lastname: Ishigaki
authors.forename: Massimo N
authors.initials: MN
authors.lastname: Ghidinelli
authors.forename: Kazuko
authors.initials: K
authors.lastname: Ikeda
authors.forename: Miwako
authors.initials: M
authors.lastname: Honda
authors.forename: Hideki
authors.initials: H
authors.lastname: Miyamoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kakimoto
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oka
mesh_terms: D000293:Adolescent; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001210:Asia, Southeastern; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000517:prevention & control / Q000635:transmission*; D006679:HIV Seropositivity; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D009035:Mothers; D012307:Risk Factors; D013240:Stereotyping; D014342:Truth Disclosure
chemical_list: D019380:Anti-HIV Agents