title: Torsade de pointes induced by citalopram and amiodarone.
abstract: Long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by a prolonged QT interval on the electrocardiogram (ECG). This disorder is associated with an increased risk of torsade de pointes (TdP). We report a case of TdP induced by citalopram, a selective serotonin reuptake inhibitor (SSRI), taken in conjunction with amiodarone.
authors.affiliation: Cardiology, Manchester hospital, Charleville-Mezieres, France. fayssoil2000@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Fayssoil
authors.forename: J
authors.initials: J
authors.lastname: Issi
authors.forename: M
authors.initials: M
authors.lastname: Guerbaa
authors.forename: J-C
authors.initials: JC
authors.lastname: Raynaud
authors.forename: V
authors.initials: V
authors.lastname: Heroguelle
mesh_terms: D000369:Aged, 80 and over; D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy*; D015283:Citalopram / Q000009:adverse effects* / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy*; D003937:Diagnosis, Differential; D004347:Drug Interactions; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008133:Long QT Syndrome / Q000139:chemically induced / Q000175:diagnosis; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000638:Amiodarone; D000889:Anti-Arrhythmia Agents; D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors