title: [Ocular syphilis: ten new cases and review of the literature].
abstract: BACKGROUND
  Ocular manifestations in patients with syphilis may involve almost any of the structures of the eye.
  
  
  OBJECTIVE
  To describe ten new cases of syphilis with eye involvement and to briefly discuss the management and therapy of such condition.
  
  
  METHODS
  Ten cases were retrospectively studied over 13 years. Demographic factors, ophthalmologic examination, and laboratory tests were assessed.
  
  
  RESULTS
  Seven of the 10 cases were male and 3 were female. The mean age of patients was 39,7 years. Disease presentation included: panuveitis (6 patients), optic neuritis (3), retinal vasculitis (1) and Argyll-Robertson pupil (1). Cerebrospinal fluid VDRL test was positive in 6 patients and 3 patients were HIV (+).
  
  
  CONCLUSIONS
  Syphilis is able to display diverse ophthalmologic manifestations. Not in all the cases the CSF-VDRL test was positive. Antitreponemal therapy generates a fast and effective response in the affected patients.
authors.affiliation: Servicio de Oftalmología, Hospital Clínico, Universidad de Chile, Santiago, Chile. pablotromero@med.uchile.cl
authors.forename: Pablo
authors.initials: P
authors.lastname: Romero C
authors.forename: Cristhían
authors.initials: C
authors.lastname: Urzúa S
authors.forename: Patricia
authors.initials: P
authors.lastname: Gallardo V
authors.forename: Juan
authors.initials: J
authors.lastname: Verdaguer T
authors.forename: Marta
authors.initials: M
authors.lastname: Lechuga C
authors.forename: Helio
authors.initials: H
authors.lastname: Hernández N
authors.forename: Felipe
authors.initials: F
authors.lastname: Sanhueza Z
authors.forename: Matías
authors.initials: M
authors.lastname: Andaur L
authors.forename: Eugenio
authors.initials: E
authors.lastname: Donaire V
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010400:Penicillin G / Q000627:therapeutic use; D012189:Retrospective Studies; D013587:Syphilis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G