title: Talin's second act-ivation: retraction.
abstract: In this issue of Blood, Haling and colleagues demonstrate that in addition to talin-dependent integrin activation, talin is required for platelet fibrin clot retraction by physically linking integrins to the actin cytoskeleton.
authors.affiliation: University of North Carolina.
authors.forename: Tina M
authors.initials: TM
authors.lastname: Leisner
authors.forename: Leslie V
authors.initials: LV
authors.lastname: Parise