title: [Prophylactic treatment with antiepileptic drugs in neurological conditions].
abstract: Prophylactic use of antiepileptic drugs in neurological conditions such as ischemic and hemorrhagic stroke, subarachnoid hemorrhage, head injury, and brain tumors has been matter of debate for many years. These drugs are used for reducing secondary neurological damage caused by epileptic seizures. However, the evidence supporting this indication is scarce. Potential drug interactions, side effects, and even neurotoxicity related to these drugs have raised concern about this therapeutic approach. In this review, we examine the evidence on the prophylactic use of antiepileptic drugs in the neurological disorders above mentioned.
authors.affiliation: Centro de Stroke, Instituto de Neurociencias de la Fundación Favaloro, Buenos Aires, Argentina. lucianosposato@gmail.com
authors.forename: Luciano A
authors.initials: LA
authors.lastname: Sposato
authors.forename: Alfredo
authors.initials: A
authors.lastname: Thomson
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Riccio
authors.forename: Analia
authors.initials: A
authors.lastname: Calle
authors.forename: Francisco R
authors.initials: FR
authors.lastname: Klein
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D001927:Brain Diseases / Q000188:drug therapy*; D001930:Brain Injuries / Q000188:drug therapy; D001932:Brain Neoplasms / Q000188:drug therapy; D006801:Humans; D020521:Stroke / Q000188:drug therapy; D013345:Subarachnoid Hemorrhage / Q000188:drug therapy
chemical_list: D000927:Anticonvulsants