title: Two new lavandulyl flavonoids from Sophora flavescens.
abstract: Two novel lavandulyl flavonoids, (2S)-7-methoxyl-4",5"-dihydroxynorkurarinone (1) and (2S)-6"-hydroxynorkurarinone-7-O-beta-D-galactoside (2), were isolated from the rhizome of Sophora flavescens. Their structures were elucidated by spectral methods, including 2D NMR spectroscopy. Both compounds showed cytotoxic activity against Hela cells, with 2 being more active than 1.
authors.affiliation: School of Science, Dalian Nationalities University, Dalian 116600, China. liudan@dlnu.edu.cn
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.forename: Xiulan
authors.initials: X
authors.lastname: Xin
authors.forename: Dong-Hai
authors.initials: DH
authors.lastname: Su
authors.forename: Junying
authors.initials: J
authors.lastname: Liu
authors.forename: Qing
authors.initials: Q
authors.lastname: Wei
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Cui
mesh_terms: D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D029909:Sophora / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: C556321:(2S)-6''-hydroxynorkurarinone-7-O-beta-D-galactoside; C556320:(2S)-7-methoxyl-4'',5''-dihydroxynorkurarinone; D005419:Flavonoids