title: Update on the management of acute pharyngitis in children.
abstract: Streptococcal pharyngitis is a very common pathology in paediatric age all over the world. Nevertheless there isn't a joint agreement on the management of this condition. Some authors recommend to perform a microbiological investigation in suspected bacterial cases in order to treat the confirmed cases with antibiotics so to prevent suppurative complications and acute rheumatic fever. Differently, other authors consider pharyngitis, even streptococcal one, a benign, self-limiting disease. Consequently they wouldn't routinely perform microbiological tests and, pointing to a judicious use of antibiotics, they would reserve antimicrobial treatment to well-selected cases. It has been calculated that the number of patients needed to treat to prevent one complication after upper respiratory tract infections (including sore throat), was over 4000. Even the use of the Centor score, in order to evaluate the risk of streptococcal infection, is under debate and the interpretation of the test results may vary considerably. Penicillin is considered all over the world as first line treatment, but oral amoxicillin is also accepted and, due to its better palatability, can be a suitable option. Macrolides should be reserved to the rare cases of proved allergy to β-lactams. Cephalosporins can be used in patients allergic to penicillin (with the exception of type I hypersensibility) and have been also proposed to treat the relapses.
authors.affiliation: Department of Sciences for Woman and Child's Health, University of Florence, Florence, Italy. marta.regoli@hotmail.it
authors.forename: Marta
authors.initials: M
authors.lastname: Regoli
authors.forename: Elena
authors.initials: E
authors.lastname: Chiappini
authors.forename: Francesca
authors.initials: F
authors.lastname: Bonsignori
authors.forename: Luisa
authors.initials: L
authors.lastname: Galli
authors.forename: Maurizio
authors.initials: M
authors.lastname: de Martino
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001431:Bacteriological Techniques / Q000379:methods*; D002648:Child; D014943:Global Health; D006801:Humans; D015994:Incidence; D010612:Pharyngitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D011379:Prognosis
chemical_list: D000900:Anti-Bacterial Agents