title: Pharmacology of sleep disorders in children and adolescents.
abstract: There is a high prevalence of sleep disorders in children and an apparent increasing need for pharmacologic management. However, because of the paucity of data available with regards to dosing, efficacy, tolerability, and safety profiles of medications as well as a lack of adequate well-designed clinical trials, medications are currently not approved for the pediatric population by the US Food and Drug Administration. There are no pharmacologic guidelines for the specific sleep disorders or the different pediatric age ranges. Additional research is needed for evidence-based pediatric sleep pharmacotherapy. This article reviews pediatric sleep disorders and the pharmacologic therapeutic options.
authors.affiliation: Sleep Medicine, Saint Mary's Neuroscience Program, Saint Mary's Neuroscience Institute, Kalamazoo, MI 49503, USA. bantuchhangani@yahoo.com
authors.forename: Bantu
authors.initials: B
authors.lastname: Chhangani
authors.forename: Donald E
authors.initials: DE
authors.lastname: Greydanus
authors.forename: Dilip R
authors.initials: DR
authors.lastname: Patel
authors.forename: Cynthia
authors.initials: C
authors.lastname: Feucht
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D015995:Prevalence; D012893:Sleep Wake Disorders / Q000188:drug therapy* / Q000453:epidemiology