title: [Case management and diagnosis of severe malaria in adults and the application of national guidelines in Burkina Faso].
abstract: The purpose of this study was to assess the application of national guidelines on the diagnosis and treatment of severe malaria in adults in Burkina Faso. We conducted a retrospective study of medical records of the patients admitted for severe malaria in the emergency service of the regional hospital of Fada N'Gourma in the east of Burkina Faso in the year 2008; 165 records were chosen by simple random sampling. We reported all the severe clinical and biological signs of malaria and its treatment. We compared them with the criteria of severe malaria diagnosis and its treatment according to the national guidelines. The mean age of patients was 38 ± 16.2 and male to female ratio was 0.96. The most frequent period of admissions was between July and October. Fever or recent past of fever was reported in 142 cases (86.1%). According to the two criteria for severe malaria (means existing of at least one of the severe signs associated and positive parasitemia with Falciparum plasmodium), we noted that only 74 cases had at least one of the severe signs (44.8%) which were: anemia (51.3%), cardiovascular collapse (7.9%), jaundice (7.3%), dyspnea (6.7%), impairment of consciousness (5.5%), prostration (5.5%), renal failure (4.8%), hypoglycemia (2.4%), hemorrhage (1.8%) and seizures (1.2%). The biological signs were not systematically searched. Parasitological exam was conducted in 91 cases (55.1%). Only 18 were positive (19.8%). In total, only 18 cases (10.9%) met the guidelines' criteria of severe malaria. The other cases were over-diagnosed; note that the investigation was not complete for 74 of these cases (50.3%). Among the 165 cases, the treatment was appropriate in 146 (88.5%) and 19 cases (11.5%) didn't receive treatment for malaria.
  
  
  CONCLUSIONS
  So much we observed an over diagnosis of severe malaria in adults that we can suggest an under diagnosis of the disease due to the lack of biological investigations.
authors.affiliation: Institut des sciences de la santé, Bobo Dioulasso, Burkina Faso. tene_yam@yahoo.fr
authors.forename: T M
authors.initials: TM
authors.lastname: Yaméogo
authors.forename: C G
authors.initials: CG
authors.lastname: Kyelem
authors.forename: S M
authors.initials: SM
authors.lastname: Ouédraogo
authors.forename: O J
authors.initials: OJ
authors.lastname: Diallo
authors.forename: L
authors.initials: L
authors.lastname: Moyenga
authors.forename: G E A
authors.initials: GE
authors.lastname: Poda
authors.forename: T R
authors.initials: TR
authors.lastname: Guiguemdé
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D002050:Burkina Faso; D005260:Female; D005334:Fever; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis* / Q000188:drug therapy* / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D018512:Parasitemia; D010963:Plasmodium falciparum; D011803:Quinine / Q000627:therapeutic use
chemical_list: D000962:Antimalarials; D011803:Quinine