title: Experiences in central pancreatectomy.
abstract: BACKGROUND
  Non-cancerous pancreatic lesions have been increasing, and function-preserving pancreatectomy may be an adequate approach to them. Recent advanced experience of major pancreatectomy has stimulated interest in central pancreatectomy (CP).
  
  
  METHODS
  Nineteen patients who underwent CP for benign and borderline malignant lesions of the pancreas from January 1990 to December 2007 were retrospectively reviewed. We also summarized recent literature reporting more than 10 cases of CP.
  
  
  RESULTS
  Nine patients (47.4%) experienced postoperative complications. Pancreatic leak was noted in 7 patients (36.8%). Two patients (10.5%) required reoperation due to intractable pancreatic leak and postoperative bleeding. No mortality was noted. During the follow-up period (median 35 months, range 3-182 months), only 1 patient (5.3%) developed new-onset diabetes after successful CP. In a comparative study, similar perioperative morbidity was noted between CP and extended distal pancreatectomy with splenectomy (extended DP-S); however, the operation time and postoperative hospital stay were significantly longer in the CP group and the incidence of new-onset diabetes was much lower in the CP group as compared with the DP-S group (p < 0.05).
  
  
  CONCLUSIONS
  CP can be carefully selected as an appropriate surgical option for benign and borderline malignant lesions limited to the pancreatic neck area.
authors.affiliation: Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Chang Moo
authors.initials: CM
authors.lastname: Kang
authors.forename: Jae-Myeong
authors.initials: JM
authors.lastname: Lee
authors.forename: Myung Wook
authors.initials: MW
authors.lastname: Kim
authors.forename: Dong Sub
authors.initials: DS
authors.lastname: Yoon
authors.forename: Joon Seong
authors.initials: JS
authors.lastname: Park
authors.forename: Woo Jung
authors.initials: WJ
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000713:Anastomosis, Roux-en-Y; D002648:Child; D002675:Child, Preschool; D003920:Diabetes Mellitus / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000601:surgery; D010180:Pancreatectomy / Q000009:adverse effects* / Q000379:methods*; D010185:Pancreatic Fistula / Q000209:etiology; D010193:Pancreaticojejunostomy; D019106:Postoperative Hemorrhage / Q000209:etiology; D012086:Reoperation; D012189:Retrospective Studies; D013156:Splenectomy / Q000009:adverse effects; D055815:Young Adult