title: The globe: infection, inflammation, and systemic disease.
abstract: Infection, inflammation, and systemic diseases affecting the globe encompass a broad range of pathologies which may ultimately lead to progressive vision loss. Clinical symptomatology varies from the inexorably silent progressive visual loss to an acute presentation of ocular pain and/or red eye. Most are diagnosed by clinical ophthalmologic examination with selective use of ultrasound, computed tomography, and magnetic resonance imaging for confirmation of the diagnosis, assessment of disease extent, and signs of associated systemic disease. Knowledge of the differential diagnoses of vision loss, ocular pain, and redness makes imaging analysis of this diverse group of processes more precise.
authors.affiliation: Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Platnick
authors.forename: Alison V
authors.initials: AV
authors.lastname: Crum
authors.forename: Stephanie
authors.initials: S
authors.lastname: Soohoo
authors.forename: Paul Anthony
authors.initials: PA
authors.lastname: Cedeño
authors.forename: Michele H
authors.initials: MH
authors.lastname: Johnson
mesh_terms: D003287:Contrast Media; D003937:Diagnosis, Differential; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology; D005128:Eye Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D015817:Eye Infections / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007239:Infections / Q000150:complications / Q000175:diagnosis; D007249:Inflammation / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media