title: Early phase 2 inpatient rehabilitation after acute coronary syndrome treated with primary percutaneous coronary intervention: short- and long-term effects on blood pressure and metabolic parameters.
abstract: OBJECTIVE
  The aim of this study was to assess the 1-yr follow-up effects of inpatient rehabilitation and its prolongation with an ambulatory training program on blood pressure and metabolic risk factors in patients after an acute coronary syndrome.
  
  
  METHODS
  A controlled (n = 20) prospective study was undertaken. The study group consisted of 54 consecutive patients participating in a 3-wk inpatient rehabilitation. Of these, 14 chose to continue the training for 3 mos (CR_In+Amb group) and 40 declined (CR_In group).
  
  
  RESULTS
  Body mass index increased in the CR_In and control groups. The magnitude of change was greater in controls (2.2 ± 2.14 vs. 0.7 ± 1.70 kg/m; P < 0.05). Waist circumference increased only in the control group, and at 12 mos, it was higher than in the CR_In and CR_In+Amb groups (P < 0.05). Mean systolic and diastolic blood pressure increased in the CR_In (from 121/76 to 130/82 mm Hg; P < 0.01) and control (from 122/74 to 139/87 mm Hg; P < 0.01) groups. At 12 mos, blood pressure in the CR_In group was lower than in the control group but higher than in the CR_In+Amb group (119/77 mm Hg; P < 0.05). Total cholesterol, low-density lipoprotein cholesterol level, and triglyceride level at 12 mos were higher in the control group than in the CR_In and CR_In+Amb groups (P < 0.05). C-reactive protein decreased in the CR_In and CR_In+Amb groups (P < 0.01).
  
  
  CONCLUSIONS
  Inpatient rehabilitation was associated with beneficial effects on blood lipids and C-reactive protein in coronary patients and attenuated the rise in blood pressure and adiposity indices observed in nonparticipants. Prolongation of rehabilitation with an ambulatory program improved blood pressure control.
authors.affiliation: Department of Cardiac Rehabilitation, University School of Physical Education, Poznan, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Deskur-Smielecka
authors.forename: Sławomira
authors.initials: S
authors.lastname: Borowicz-Bienkowska
authors.forename: Mariola
authors.initials: M
authors.lastname: Maleszka
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Wilk
authors.forename: Alicja
authors.initials: A
authors.lastname: Nowak
authors.forename: Izabela
authors.initials: I
authors.lastname: Przywarska
authors.forename: Piotr
authors.initials: P
authors.lastname: Dylewicz
mesh_terms: D054058:Acute Coronary Syndrome / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D015906:Angioplasty, Balloon, Coronary / Q000534:rehabilitation; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D015331:Cohort Studies; D005260:Female; D006760:Hospitalization; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012047:Rehabilitation Centers; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D008055:Lipids; D002097:C-Reactive Protein