title: Infection of humans and animals with Echinococcus granulosus (G1 and G3 strains) and E. ortleppi in Southern Brazil.
abstract: The Rio Grande do Sul state, in Southern Brazil, is one of the foci of human cystic echinococcosis (CE). The sheep strain (G1) of Echinococcus granulosus and Echinococcus ortleppi (also known as cattle strain G5) have been reported before to infect livestock. However, up to the present, no molecular data are available on isolates of the E. granulosus complex from humans and dogs. The present study analyzed hydatid cysts from 6 CE patients and adult worms from 12 dogs. Sequencing of the mitochondrial cox1 and 12S rRNA genes detected the E. granulosus G1 genotype from four human cases, the G3 genotype (or buffalo strain) from one human case and E. ortleppi from another human case, respectively. Ten of the twelve dogs were found infected with the G1 genotype, and one dog each harbored worms of the G3 genotype and E. ortleppi. Obvious morphological differences were recognized between the G1 and E. ortleppi adult worms from dogs in this region. The buffalo strain (G3) is for the first time reported from South America.
authors.affiliation: Microbiology and Parasitology Department, Federal University of S. Maria, Av. Roraima 1000, 97.105-900 S. Maria, RS, Brazil. mldelarue@hotmail.com
authors.forename: Mario L
authors.initials: ML
authors.lastname: de la Rue
authors.forename: Keishi
authors.initials: K
authors.lastname: Takano
authors.forename: Joaquim F
authors.initials: JF
authors.lastname: Brochado
authors.forename: Carmem V
authors.initials: CV
authors.lastname: Costa
authors.forename: Antonio G
authors.initials: AG
authors.lastname: Soares
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Yamano
authors.forename: Kinpei
authors.initials: K
authors.lastname: Yagi
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Katoh
authors.forename: Kenichi
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000818:Animals; D001483:Base Sequence; D001938:Brazil / Q000453:epidemiology; D004272:DNA, Mitochondrial / Q000235:genetics; D004443:Echinococcosis / Q000453:epidemiology / Q000469:parasitology*; D004446:Echinococcus / Q000145:classification* / Q000235:genetics; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D013045:Species Specificity
chemical_list: D004272:DNA, Mitochondrial