title: Management of severe asthma in children.
abstract: BACKGROUND
  Asthma is the most common chronic disease of childhood and the leading cause of childhood morbidity from chronic disease. When uncontrolled, asthma can place significant limits on daily life, and is sometimes fatal.
  
  
  OBJECTIVE
  This article describes the initial assessment and management of status asthmaticus in children.
  
  
  CONCLUSIONS
  Status asthmaticus is a medical emergency in which asthma symptoms are refractory to initial bronchodilator therapy. Patients may report chest tightness, rapidly progressive shortness of breath, dry cough and wheezing. Typically, patients present a few days after the onset of a viral respiratory illness, following exposure to potent allergens or irritants, or after exercise in a cold environment, however, they can also present with sudden onset of symptoms with an unknown trigger. Early recognition and initiation of therapy is vital in preventing severe complications such as respiratory failure. Aggressive treatment with beta-agonists, anticholinergics and corticosteroids remains the gold standard for this condition.
authors.affiliation: Department of Emergency Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia. adriana.yockcorrales@rch.org.au
authors.forename: Adriana
authors.initials: A
authors.lastname: Yock Corrales
authors.forename: Manuel
authors.initials: M
authors.lastname: Soto-Martinez
authors.forename: Mike
authors.initials: M
authors.lastname: Starr
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D002908:Chronic Disease / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors
chemical_list: D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D001993:Bronchodilator Agents; D018680:Cholinergic Antagonists