title: Multicomponent synthesis of chiral sulfinimines.
abstract: Two oxathiozolidine-S-oxide templates have been developed and used in a four-component coupling protocol for the synthesis of a wide range of chiral sulfinimines in high enantiomeric excesses. The templates can be synthesized from cheap commodity chemicals in three steps in high yields. Furthermore the template is easily recovered in high yields for recycling.
authors.affiliation: School of Chemistry, University of Nottingham, Nottingham, UK.
authors.forename: Caroline
authors.initials: C
authors.lastname: Roe
authors.forename: Heather
authors.initials: H
authors.lastname: Hobbs
authors.forename: Robert A
authors.initials: RA
authors.lastname: Stockman
mesh_terms: D020650:Combinatorial Chemistry Techniques; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010087:Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D053778:Thiazolidines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007097:Imines; D010087:Oxides; D013452:Sulfonium Compounds; D053778:Thiazolidines; C522016:sulfinimine