title: The Sino-Nasal Outcome Test 22 validated for Danish patients.
abstract: BACKGROUND
  Chronic rhinosinusitis (CRS) is a significant health problem whose incidence and prevalence is rising. It calls into attention consensus about diagnosing, assessing symptoms and treatment of patients with CRS. Therefore, a validated Danish measure of health-related quality of life in sinonasal disease is needed.
  
  
  METHODS
  The Sino-Nasal Outcome Test 22 (SNOT-22) was translated into Danish and its reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical analyses used were Pearson's correlation coefficient, Cronbach's alpha, kappa and Bland-Altman's plot. Reproducibility was also tested for SNOT-22 subscales.
  
  
  RESULTS
  The results show good internal correlation with a Cronbach's alpha of 0.83 in the initial test and one of 0.92 in the retest. Pearson's correlation coefficient was 0.70 (p < 0.001), revealing good correlation between the initial scores and the retests scores. Kappa was calculated for each item with a mean value of 0.61 showing substantial agreement. The paired t-test revealed no significant difference between the subscales.
  
  
  CONCLUSIONS
  The Danish version of SNOT-22 is recommended for Danish clinicians and researchers as a patient-reported measure of outcome in sinonasal disorders such as rhinosinusitis and nasal polyposis.
authors.affiliation: Department of Otorhinolaryngology, Odense University Hospital, Denmark. bibi.lange@ouh.regionsyddanmark.dk
authors.forename: Bibi
authors.initials: B
authors.lastname: Lange
authors.forename: Trine
authors.initials: T
authors.lastname: Thilsing
authors.forename: Abir
authors.initials: A
authors.lastname: Al-kalemji
authors.forename: Jesper
authors.initials: J
authors.lastname: Baelum
authors.forename: Torben
authors.initials: T
authors.lastname: Martinussen
authors.forename: Anette
authors.initials: A
authors.lastname: Kjeldsen
mesh_terms: D000328:Adult; D000368:Aged; D003718:Denmark; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D012220:Rhinitis / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology; D012720:Severity of Illness Index; D012852:Sinusitis / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology; D013223:Statistics as Topic; D011795:Surveys and Questionnaires / Q000592:standards*