title: Increased liver and spleen accumulation of Tc-99m methylene diphosphonate associated with intravenous injection of MRI contrast gadolinium-diethylenetriaminepentaacetic acid.
abstract: Several conditions that can cause diffuse hepatic or splenic uptake of Tc-99m methylene diphosphonate (Tc-99m MDP) have been previously reported. Nevertheless, diffuse abnormal liver and spleen uptake of Tc-99m MDP associated with intravenous injection of magnetic resonance imaging contrast gadolinium-diethylenetriaminepentaacetic acid is not previously known. In our series, we reported diffuse increased Tc-99m MDP activity in the liver and spleen in bone scans in patients who received Tc-99m MDP injection shortly after contrast-enhanced magnetic resonance imaging.
authors.affiliation: Department of Nuclear Medicine, The Third Teaching Hospital of Peking University, Beijing, People's Republic of China.
authors.forename: Weifang
authors.initials: W
authors.lastname: Zhang
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xinxin
authors.initials: X
authors.lastname: Li
authors.forename: Zhonghui
authors.initials: Z
authors.lastname: Jin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D019786:Gadolinium DTPA / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D008099:Liver / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging*; D013669:Technetium Tc 99m Medronate; D051598:Whole Body Imaging
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA; D013669:Technetium Tc 99m Medronate