title: Simultaneous excision of ipsilateral nonpalpable multiple breast lesions using radioguided occult lesion localization.
abstract: The purpose of this study was to determine the feasibility and effectiveness of ROLL technique for the identification and excision of ipsilateral nonpalpable multiple breast lesions. Between August 2005 and August 2010, eight women, aged 40-61 years, with a radiographic evidence of two separate nonpalpable lesions within the same breast underwent ROLL, as we termed it, double-ROLL. Each lesion was localized with Tc-99m-labeled human serum albumin macroaggregate under ultrasonography or mamography control. A gamma probe was used to guide surgical excisions. There was no radiotracer overlapping or extravasation in any case. Out of the 16 resected specimens, histopathologic examination revealed benign findings in 13 lesions and malignancy in 3. There was no lesion involvement at the surgical margins, and no residuals were detected in any of the benign cases during follow-up. Double-ROLL technique is feasible and safe for the identification and excision of such multiple ipsilateral breast lesions.
authors.affiliation: Department of General Surgery, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey. memetoplantisi@yahoo.com
authors.forename: Fatih
authors.initials: F
authors.lastname: Aydogan
authors.forename: Volkan
authors.initials: V
authors.lastname: Ozben
authors.forename: Mehmet Halit
authors.initials: MH
authors.lastname: Yilmaz
authors.forename: Varol
authors.initials: V
authors.lastname: Celik
authors.forename: Cihan
authors.initials: C
authors.lastname: Uras
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ferahman
authors.forename: Anar
authors.initials: A
authors.lastname: Aliyev
authors.forename: Hilal
authors.initials: H
authors.lastname: Unal
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin