title: Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis.
abstract: The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs-Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also reported.
authors.affiliation: School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
authors.forename: Lidia A
authors.initials: LA
authors.lastname: Maslovskaya
authors.forename: Andrei I
authors.initials: AI
authors.lastname: Savchenko
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Gordon
authors.forename: Paul W
authors.initials: PW
authors.lastname: Reddell
authors.forename: Carly J
authors.initials: CJ
authors.lastname: Pierce
authors.forename: Peter G
authors.initials: PG
authors.lastname: Parsons
authors.forename: Craig M
authors.initials: CM
authors.lastname: Williams
mesh_terms: D045784:Abietanes; D002974:Clemastine; D029802:Croton / Q000737:chemistry*; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D045784:Abietanes; D004224:Diterpenes; C557936:cleistanthol; C024715:Spruceanol; D002974:Clemastine