title: Ruthenium-catalyzed regioselective [2 + 2 + 2] cyclotrimerization of trifluoromethyl group substituted internal alkynes.
abstract: It found that the Ru(3)(CO)(12) coordinated with 2-(diphenylphosphino)benzonitrile (2-DPPBN) to effectively catalyze the [2 + 2 + 2] cyclotrimerization of the trifluoromethyl group substituted internal alkynes in high yields with up to >98% regioselectivity. Isolation of a ruthenacyclopentadiene was successful and confirmed that the complex is a reaction intermediate.
authors.affiliation: Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Koyama, Tottori, Japan. kawatsur@chem.tottori-u.ac.jp
authors.forename: Motoi
authors.initials: M
authors.lastname: Kawatsura
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Junya
authors.initials: J
authors.lastname: Namioka
authors.forename: Koji
authors.initials: K
authors.lastname: Kajita
authors.forename: Takuya
authors.initials: T
authors.lastname: Hirakawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Itoh
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D005464:Fluorobenzenes / Q000138:chemical synthesis* / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C557934:2-(diphenylphosphino)benzonitrile; D000480:Alkynes; D005464:Fluorobenzenes; D006845:Hydrocarbons, Fluorinated; D009570:Nitriles; D010720:Phosphines; D012428:Ruthenium