title: Dysfunctions of the Iga system: a common link between intestinal and renal diseases.
abstract: Immunoglobulin A (Iga)-isotype antibodies play an important role in immunity owing to their structure, glycosylation, localization and receptor interactions. Dysfunctions in this system can lead to multiple types of pathology. This review describes the characteristics of Iga and discusses the involvement of abnormalities in the Iga system on the development of celiac disease and Iga nephropathy.
authors.affiliation: INSERM U699, Paris 75018, France.
authors.forename: Christina
authors.initials: C
authors.lastname: Papista
authors.forename: Laureline
authors.initials: L
authors.lastname: Berthelot
authors.forename: Renato C
authors.initials: RC
authors.lastname: Monteiro
mesh_terms: D002446:Celiac Disease / Q000276:immunology* / Q000503:physiopathology*; D005922:Glomerulonephritis, IGA / Q000276:immunology* / Q000503:physiopathology*; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis / Q000737:chemistry / Q000276:immunology*; D011971:Receptors, Immunologic / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D011971:Receptors, Immunologic