title: Copper catalyzed C-H functionalization for direct Mannich reactions.
abstract: A protocol for a practical and direct addition of α- and γ-alkyl azaarenes to N-sulfonyl aldimines has been developed. Copper salts act as efficient Lewis acid catalysts for direct Mannich-type reactions providing a mild and fast access to various functionalized heterocycles.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Aachen, Germany. Magnus.Rueping@rwth-aachen.de
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
authors.forename: Nikita
authors.initials: N
authors.lastname: Tolstoluzhsky