title: Associations between alcohol consumption and sleep-disordered breathing among Japanese women.
abstract: BACKGROUND
  The associations between alcohol consumption and sleep-disordered breathing in women are uncertain.
  
  
  METHODS
  We conducted a cross-sectional study of 3113 women aged 30-69 years. The 3% oxygen desaturation index (3% ODI), based on overnight pulse oximetry findings, was selected as an indicator of sleep-disordered breathing.
  
  
  RESULTS
  3% ODI frequencies of ≥5 were higher for drinking women with ethanol intakes of ≥23.0 g/d than for never drinkers: the respective multivariable odds ratios and 95% confidence intervals was 1.8(1.0-3.4). The corresponding odds ratio was 3.0(1.6-5.8) for habitual snoring. The associations of ethanol intakes of ≥23.0 g/d with 3% ODI ≥ 5 was more evident among women with BMI <23.0 kg/m(2) (median) than those with higher BMI but did not vary by habitual snoring. The multivariable odds ratios of 3%ODI ≥ 5 for women with ethanol intakes of ≥23.0 g/d versus never drinkers were 2.7(1.0-6.7) for lower BMI and 1.5(0.6-3.3) for higher BMI and the corresponding odds ratio were 2.8(1.6-7.2) and 3.2(1.3-7.9) for habitual snoring, respectively.
  
  
  CONCLUSIONS
  Alcohol consumption was associated with higher prevalence of sleep-disordered breathing among Japanese women.
authors.affiliation: Public Health, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka Suita-City, Osaka 565-0871, Japan. cui@pbhel.med.osaka-u.ac.jp
authors.forename: Renzhe
authors.initials: R
authors.lastname: Cui
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tanigawa
authors.forename: Susumu
authors.initials: S
authors.lastname: Sakurai
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Yamagishi
authors.forename: Isao
authors.initials: I
authors.lastname: Muraki
authors.forename: Hironori
authors.initials: H
authors.lastname: Imano
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ohira
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kiyama
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kitamura
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iso
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology / Q000503:physiopathology; D044466:Asian People; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D010092:Oximetry; D012891:Sleep Apnea Syndromes / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology