title: Graves' disease in a Down's syndrome patient.
abstract: Thyroid dysfunction in patients with Down's syndrome is well known. Although the majority of children with Down's syndrome appear to have normal thyroid function, however, hypothyroidism is commonly seen. The presence of hyperthyroidism is rare. The etiology is believed to be autoimmune. We report a patient with Down syndrome and Graves' disease who responded well to antithyroid drugs. The rarity of this association, especially in a child younger than eight years of age, has prompted us to report this case.
authors.affiliation: Departments of Medicine and Nuclear Medicine, Govt Medical College and SK Institute of Medical Sciences, Srinagar Kashmir-190012, India. hayatmb@rediffmail.com
authors.forename: Mohammad Hayat
authors.initials: MH
authors.lastname: Bhat
authors.forename: Sameena
authors.initials: S
authors.lastname: Saba
authors.forename: Irfan
authors.initials: I
authors.lastname: Ahmed
authors.forename: M M A
authors.initials: MM
authors.lastname: Kamili
authors.forename: Shaukat A
authors.initials: SA
authors.lastname: Khan
mesh_terms: D002648:Child; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006111:Graves Disease / Q000188:drug therapy / Q000209:etiology*; D006801:Humans