title: Correction of left ventricular wall thickening from short-axis cine MRI for basal-descent through-plane motion.
abstract: OBJECTIVE
  To solve the problem of the basal descent movement in quantification of the regional left ventricular (LV) myocardial wall thickness (WTh) and wall thickening (%WT) in short-axis (SA) cine MRI for effectively assessing the regional wall motion of LV myocardium.
  
  
  METHODS
  LV long-axis tagged MRI and SA cine MRI were performed to calculate the longitudinal translation and circumferential WTh of LV myocardium in eight normal volunteers. The new SA end-systolic thickness (EST) data were reconstructed from the original EST data, based on the quantified longitudinal translation of LV myocardium.
  
  
  RESULTS
  The mean %WT of six segments in the basal section after correction was significantly different from that before correction in both intra- and inter-operator experiments. The polar map also showed the significant improvement of the variability of regional %WT and lack of quantification of %WT in the most basal SA slices after correction.
  
  
  CONCLUSIONS
  The proposed technique demonstrated an important advantage to calculate the %WT in the most basal SA myocardial tissue, which was considered difficult to be achieved using cine MRI.
authors.affiliation: Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan. hubt@vghtc.gov.tw
authors.forename: Jyh-Wen
authors.initials: JW
authors.lastname: Chai
authors.forename: Wei-Hsun
authors.initials: WH
authors.lastname: Chen
authors.forename: Hsian-Min
authors.initials: HM
authors.lastname: Chen
authors.forename: Chih-Ming
authors.initials: CM
authors.lastname: Chiang
authors.forename: Jin-Long
authors.initials: JL
authors.lastname: Huang
authors.forename: Jachih
authors.initials: J
authors.lastname: Fu
authors.forename: Clayton
authors.initials: C
authors.lastname: Chi-Chang Chen
authors.forename: San-Kan
authors.initials: SK
authors.lastname: Lee
mesh_terms: D000328:Adult; D000465:Algorithms; D016477:Artifacts; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity