title: Early Treatment for Women with Alcohol Addiction (EWA) reduces mortality: a randomized controlled trial with long-term register follow-up.
abstract: OBJECTIVE
  To compare the mortality of female alcoholics randomly assigned to the woman-only programme 'Early treatment for Women with Alcohol Addiction' (EWA) versus those who received mixed gender 'Treatment As Usual' (TAU).
  
  
  METHODS
  Randomized controlled trial involving 2-year follow-up by personal interview and mortality register data through 27 years of 200 women first time treated for alcohol use disorder (AUD; EWA, n = 100 and TAU, n = 100), who were consecutively recruited during 1983-1984. Data from the Causes of Death Register were used to test for mortality differences related to group interaction predictors such as age, inpatient versus outpatient status at intake and 2-year drinking outcome.
  
  
  RESULTS
  Significantly lower mortality was found among younger women who participated in EWA compared with those who received TAU. This difference lasted nearly 20 years after intake to treatment. For women who only needed outpatient treatment, reduced mortality was found in the EWA group, even for older women. Increased mortality was found for TAU women who did not attend the 2-year follow-up compared with those who attended; no such difference was found for EWA women. This indicates different attrition mechanisms in the two groups. Thus, previously reported treatment effects may have been underestimated. EWA was a more comprehensive programme than TAU while also being single gender.
  
  
  CONCLUSIONS
  EWA, specifically developed to meet a broad spectrum of problems among women with AUDs, was more effective than TAU, a mixed gender programme. It was not possible to separate whether this was in part because it was a more comprehensive programme, as well as being single gender.
authors.affiliation: Department of Clinical Medicine, Section for Psychiatry, University of Bergen, N-5020 Bergen, Norway. rolf@gjestad.biz
authors.forename: Rolf
authors.initials: R
authors.lastname: Gjestad
authors.forename: Johan
authors.initials: J
authors.lastname: Franck
authors.forename: Staffan
authors.initials: S
authors.lastname: Lindberg
authors.forename: Brit
authors.initials: B
authors.lastname: Haver
mesh_terms: D000367:Age Factors; D000437:Alcoholism / Q000401:mortality* / Q000517:prevention & control / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D055502:Secondary Prevention; D012737:Sex Factors; D059039:Standard of Care; D013695:Temperance; D013997:Time Factors