title: Reversal of hypercoagulability with hydroxyethyl starch during transplantation: a case series.
abstract: During transplant surgery, clot formation resulting in life-threatening thromboembolic phenomena or graft loss may be a consequence unless close monitoring of coagulation and anticoagulation treatment is instituted in a timely manner. Three cases with a hypercoagulable state, as determined by thrombelastography at the time of surgery, but whose hypercoagulation was gradually attenuated with hydroxyethyl starch infusion during transplantation, are presented.
authors.affiliation: Division of Solid Organ Transplantation, Department of Anesthesiology, Preoperative Medicine and Pain Management, University of Miami, Leonard Miller School of Medicine, Miami, FL 33136, USA. kfukazawa@med.miami.edu
authors.forename: Kyota
authors.initials: K
authors.lastname: Fukazawa
authors.forename: Ernesto A
authors.initials: EA
authors.lastname: Pretto
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D007422:Intestines / Q000637:transplantation; D007431:Intraoperative Complications / Q000188:drug therapy*; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D016377:Organ Transplantation / Q000009:adverse effects*; D016035:Pancreas Transplantation / Q000009:adverse effects; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000627:therapeutic use*; D013916:Thrombelastography; D019851:Thrombophilia / Q000188:drug therapy*
chemical_list: D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes