title: [Neuroimaging technique: a diagnostic tool to detect altered states of consciousness].
abstract: Vegetative and minimally conscious states diagnosis remained a major clinical challenge. New paradigms such as measurement of the global cerebral metabolism, the structural and functional integrity of fronto-parietal network, or the spontaneous activity in resting state have been shown to be helpful to disentangle vegetative from minimally conscious patients. Active neuroimagery paradigms also allow detecting voluntary and conscious activity in non-communicative patients. The implementation of these methods in clinical routine could permit to reduce the current high rate of misdiagnosis (40%).
authors.affiliation: Coma Science group, Centre de Recherches du Cyclotron, Université et Centre Hospitalier Universitaire de Liège, Sart-Tilman, B30, 4000 Liège, Belgique.
authors.forename: Marie
authors.initials: M
authors.lastname: Thonnard
authors.forename: Mélanie
authors.initials: M
authors.lastname: Boly
authors.forename: Marie-Aurélie
authors.initials: MA
authors.lastname: Bruno
authors.forename: Camille
authors.initials: C
authors.lastname: Chatelle
authors.forename: Olivia
authors.initials: O
authors.lastname: Gosseries
authors.forename: Steven
authors.initials: S
authors.lastname: Laureys
authors.forename: Audrey
authors.initials: A
authors.lastname: Vanhaudenhuyse
mesh_terms: D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D001926:Brain Death / Q000175:diagnosis; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D003143:Communication Devices for People with Disabilities; D003244:Consciousness Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003951:Diagnostic Errors; D003943:Diagnostic Techniques, Neurological; D006801:Humans; D007092:Imagination; D008279:Magnetic Resonance Imaging; D010812:Physical Stimulation; D049268:Positron-Emission Tomography; D014474:Unconsciousness / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D014836:Volition