title: Successful treatment of acute promyelocytic leukemia in a patient on hemodialysis.
abstract: Acute promyelocytic leukemia (APL) has the best prognosis among acute leukemias, but there is little data about APL in patients on hemodialysis. A 64-year-old hemodialysis patient was successfully treated for APL by induction therapy with all-trans retinoic acid (ATRA), three courses of consolidation therapy with Ara-C, mitomycin C (MIT), daunorubicin (DNR), and idarubicin (IDR), and maintenance therapy with ATRA. Complete remission has been maintained for 42 months in this patient. With dose modification, ATRA and chemotherapy may be safely given to patients on hemodialysis.
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan. yoshiki1209@gmail.com.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Tsuchiya
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Ubara
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Suwabe
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Hoshino
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Sumida
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Rikako
authors.initials: R
authors.lastname: Hiramatsu
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Eiko
authors.initials: E
authors.lastname: Hasegawa
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yamanouchi
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Hayami
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Marui
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Sawa
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Fumi
authors.initials: F
authors.lastname: Takemoto
authors.affiliation: Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa, 213-8587, Japan.
authors.forename: Kenmei
authors.initials: K
authors.lastname: Takaichi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015255:Idarubicin / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000150:complications*; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D012074:Remission Induction; D006435:Renal Dialysis; D014212:Tretinoin / Q000008:administration & dosage
chemical_list: D003561:Cytarabine; D016685:Mitomycin; D014212:Tretinoin; D015255:Idarubicin; D003630:Daunorubicin