title: A large palindrome with interchromosomal gene duplications in the pericentromeric region of the D. melanogaster Y chromosome.
abstract: The non-recombining Y chromosome is expected to degenerate over evolutionary time, however, gene gain is a common feature of Y chromosomes of mammals and Drosophila. Here, we report that a large palindrome containing interchromosomal segmental duplications is located in the vicinity of the first amplicon detected in the Y chromosome of D. melanogaster. The recent appearance of such amplicons suggests that duplications to the Y chromosome, followed by the amplification of the segmental duplications, are a mechanism for the continuing evolution of Drosophila Y chromosomes.
authors.affiliation: Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Méndez-Lago
authors.forename: Casey M
authors.initials: CM
authors.lastname: Bergman
authors.forename: Beatriz
authors.initials: B
authors.lastname: de Pablos
authors.forename: Alan
authors.initials: A
authors.lastname: Tracey
authors.forename: Siobhan L
authors.initials: SL
authors.lastname: Whitehead
authors.forename: Alfredo
authors.initials: A
authors.lastname: Villasante
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics*; D019143:Evolution, Molecular; D020440:Gene Duplication; D017344:Genes, Insect; D055029:Inverted Repeat Sequences; D008957:Models, Genetic; D008969:Molecular Sequence Data; D014998:Y Chromosome