title: Imipenem disc for detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice.
abstract: The global spread of class A-carbapenemase-producing Enterobacteriaceae has made the development of a simple test a desirable goal. A disc diffusion test using imipenem was 100% sensitive and 96% specific in identifying carbapenemase-producing organisms, potentially reducing or eliminating the need for the relatively labor-intensive modified Hodge test.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, P.O. Box 12000, Jerusalem 91120, Israel. Benenson@Hadassah.org.il
authors.forename: Shmuel
authors.initials: S
authors.lastname: Benenson
authors.forename: Violeta
authors.initials: V
authors.lastname: Temper
authors.forename: Matan J
authors.initials: MJ
authors.lastname: Cohen
authors.forename: Carmela
authors.initials: C
authors.lastname: Schwartz
authors.forename: Carlos
authors.initials: C
authors.lastname: Hidalgo-Grass
authors.forename: Colin
authors.initials: C
authors.lastname: Block
mesh_terms: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins / Q000032:analysis*; D001431:Bacteriological Techniques / Q000379:methods*; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D015378:Imipenem; D012680:Sensitivity and Specificity; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015378:Imipenem; D001618:beta-Lactamases; C063912:carbapenemase