title: Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1.
abstract: It is essential that there be consistency in the conduct, analysis, and reporting of clinical trial results in myeloma. The goal of the International Myeloma Workshop Consensus Panel 1 was to develop a set of guidelines for the uniform reporting of clinical trial results in myeloma. This paper provides a summary of the current response criteria in myeloma, detailed definitions for patient populations, lines of therapy, and specific endpoints. We propose that future clinical trials in myeloma follow the guidelines for reporting results proposed in this manuscript.
authors.affiliation: Mayo Clinic, Rochester, MN, USA. rajks@mayo.edu
authors.forename: S Vincent
authors.initials: SV
authors.lastname: Rajkumar
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Harousseau
authors.forename: Brian
authors.initials: B
authors.lastname: Durie
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Anderson
authors.forename: Meletios
authors.initials: M
authors.lastname: Dimopoulos
authors.forename: Robert
authors.initials: R
authors.lastname: Kyle
authors.forename: Joan
authors.initials: J
authors.lastname: Blade
authors.forename: Paul
authors.initials: P
authors.lastname: Richardson
authors.forename: Robert
authors.initials: R
authors.lastname: Orlowski
authors.forename: David
authors.initials: D
authors.lastname: Siegel
authors.forename: Sundar
authors.initials: S
authors.lastname: Jagannath
authors.forename: Thierry
authors.initials: T
authors.lastname: Facon
authors.forename: Hervé
authors.initials: H
authors.lastname: Avet-Loiseau
authors.forename: Sagar
authors.initials: S
authors.lastname: Lonial
authors.forename: Antonio
authors.initials: A
authors.lastname: Palumbo
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Zonder
authors.forename: Heinz
authors.initials: H
authors.lastname: Ludwig
authors.forename: David
authors.initials: D
authors.lastname: Vesole
authors.forename: Orhan
authors.initials: O
authors.lastname: Sezer
authors.forename: Nikhil C
authors.initials: NC
authors.lastname: Munshi
authors.forename: Jesus
authors.initials: J
authors.lastname: San Miguel
mesh_terms: D002986:Clinical Trials as Topic; D017326:Clinical Trials, Phase III as Topic; D006801:Humans; D009101:Multiple Myeloma / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome