title: [Coexistence of multifocal gastric adenocarcinoma with signet-ring cell morphology and a gastrointestinal stromal tumour in a stomach with hp-associated gastritis].
abstract: A 79-year-old man was admitted because of anemia during marcumar therapy with suspected bleeding in the gastrointestinal tract. Endoscopy revealed a large mutifocal poorly differentiated gastric signet ring cell adenocarcinoma. After staging by the usual oesophagogastroduodenoscopic method, a total D 2 gastrectomy was performed. In the pathological resection specimen of the stomach, a multifocal poorly differentiated signet ring cell adenocarcinoma, infiltrating the submucosa (so called early cancer of sm-type) and an incidental gastroinstinal stromal tumour, 0.8 cm in diameter, was diagnosed. This is the first case report of the synchronous occurrence of a multifocal poorly differentiated gastric adenocarcinoma with signet-ring cell morphology (diffuse type according to the Lauren classification) and a GIST incidentally within a stomach with Hp-associated gastritis.
authors.affiliation: Innere Medizin, Klinik Blankenstein. vogels@arcormail.de
authors.forename: Y
authors.initials: Y
authors.lastname: Vogel
authors.forename: C
authors.initials: C
authors.lastname: Müller
authors.forename: W
authors.initials: W
authors.lastname: Uhl
authors.forename: A
authors.initials: A
authors.lastname: Tannapfel
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D000368:Aged; D005756:Gastritis / Q000150:complications* / Q000473:pathology; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000473:pathology*; D016481:Helicobacter Infections / Q000150:complications* / Q000473:pathology; D006801:Humans; D033162:Incidental Findings; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000473:pathology*; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*