title: A case of erythema multiforme associated with primary Epstein-Barr virus infection.
abstract: We present a case of primary Epstein-Barr virus (EBV) infection with erythema multiforme. A 1-year-old Japanese boy presented with skin eruptions, including typical target lesions and a low-grade fever. Just before the skin biopsy, 95 copies/μg DNA of EBV genome was detected in peripheral blood mononuclear cells, which subsequently increased to 6,834 copies/μg DNA. Skin tissue collected from the skin lesion showed the typical pathologic findings of erythema multiforme. EBV-encoded small nuclear RNA signals were not detected in the skin tissue by in situ hybridization.
authors.affiliation: Department of Pediatrics, Fujita Health University School of Medicine, Aichi, Japan.
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Nakai
authors.forename: Ken
authors.initials: K
authors.lastname: Sugata
authors.forename: Chie
authors.initials: C
authors.lastname: Usui
authors.forename: Yoshizo
authors.initials: Y
authors.lastname: Asano
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamakita
authors.forename: Kayoko
authors.initials: K
authors.lastname: Matsunaga
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Mizokuchi
authors.forename: Harutaka
authors.initials: H
authors.lastname: Katano
authors.forename: Keiji
authors.initials: K
authors.lastname: Iwatsuki
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Yoshikawa
mesh_terms: D004279:DNA, Viral / Q000302:isolation & purification; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D004892:Erythema Multiforme / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D005334:Fever / Q000821:virology; D006801:Humans; D007223:Infant; D007963:Leukocytes, Mononuclear / Q000821:virology; D008297:Male
chemical_list: D004279:DNA, Viral