title: Formal total synthesis of cyanolide A.
abstract: Formal total synthesis of cyanolide A, aglycosidic dimeric macrolide is accomplished. The key reactions involved are asymmetric acetate aldol reaction, CBS reduction, and Shiina's lactonization.
authors.affiliation: Organic Division-I, Indian Institute of Chemical Technology, CSIR, Hyderabad-500607, India. srihari@iict.res.in
authors.forename: Srihari
authors.initials: S
authors.lastname: Pabbaraja
authors.forename: K
authors.initials: K
authors.lastname: Satyanarayana
authors.forename: B
authors.initials: B
authors.lastname: Ganganna
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D019281:Dimerization; D006801:Humans; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D051379:Mice
chemical_list: D000970:Antineoplastic Agents; D018942:Macrolides; C548188:cyanolide A