title: Clinical outcome of open and laparoscopic surgery in Dukes' B and C rectal cancer: experience from a regional hospital in Hong Kong.
abstract: OBJECTIVE
  To compare the long-term outcome of open and laparoscopic surgery for Dukes' B and C rectal cancer in a regional hospital in Hong Kong.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  A regional hospital in Hong Kong.
  
  
  METHODS
  Survival and local recurrence rates.
  
  
  METHODS
  Patients with Dukes' B and C rectal cancers underwent elective curative open or laparoscopic surgery during the period December 2000 to December 2006.
  
  
  RESULTS
  A total of 222 patients (open surgery, n=133; laparoscopic surgery, n=89) were assessed. The overall 3- and 5-year survival rates for all patients were 72% and 58%, respectively. Local recurrence rates were similar in both groups. Laparoscopic group had better overall survival (P=0.014), however. The overall 3-year survival rates were 79% and 68% in the laparoscopic and open groups, respectively. The corresponding 5-year rates were 75% and 52%. Multivariate analysis also demonstrated that laparoscopic surgery was a significant independent factor for better survival. Chemotherapy, local recurrence, lymph node metastasis, and poorly differentiated tumour were significantly associated with survival.
  
  
  CONCLUSIONS
  Laparoscopic surgery for Dukes' B and C rectal cancer was associated with more favourable survival than with open surgery.
authors.affiliation: Department of Surgery, Kwong Wah Hospital, 25 Waterloo Road, Hong Kong. weidaday@gmail.com
authors.forename: W
authors.initials: W
authors.lastname: Day
authors.forename: P Y Y
authors.initials: PY
authors.lastname: Lau
authors.forename: K M
authors.initials: KM
authors.lastname: Li
authors.forename: S Y
authors.initials: SY
authors.lastname: Kwok
authors.forename: A W C
authors.initials: AW
authors.lastname: Yip
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D012004:Rectal Neoplasms / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome