title: Antigen presentation to B cells.
abstract: B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers. Here, we discuss a number of recent imaging studies that have provided new insights into the variety of mechanisms by which B-cell activation is initiated in the lymph node in vivo.
authors.affiliation: Lymphocyte Interaction Laboratory, London Research Institute, Cancer Research UK 44 Lincoln's Inn Fields, London WC2A 3LY UK.
authors.forename: Naomi E
authors.initials: NE
authors.lastname: Harwood
authors.forename: Facundo D
authors.initials: FD
authors.lastname: Batista