title: Liquid chromatography coupled with tandem mass spectrometry method for thirty-three pesticides in natural water and comparison of performance between classical solid phase extraction and passive sampling approaches.
abstract: The aim of this study is to propose an analytical method for determining different classes of pesticides in water using LC-ESI-MS/MS. Two techniques of field-sampling and analyte extraction were used: solid phase extraction (SPE) of water samples from active sampling and field exposure of Polar Organic Chemical Integrative Samplers (POCIS). We have worked with thirty-three molecules representing eight pesticide classes: carbamates, chloroacetanilides, dicarboximides, morpholines, organophosphorous, phenylureas, strobilurines and triazines. First, liquid chromatography separation protocols and the optimization of the ESI-MS/MS parameters were developed. Then, the SPE step was optimized to obtain acceptable levels of recovery for the various classes of molecules. The matrix effect that may significantly lower the ionization efficiency with ESI interfaces was evaluated and minimized. The performances (limits of quantification, accuracy and precision) of the SPE and POCIS techniques were evaluated, and a comparison between the active and passive sampling techniques was carried out with a field application.
authors.affiliation: CEMAGREF, REBX Unit, 50 Avenue de Verdun, 33612 Cestas, France. sophie.lissalde@cemagref.fr
authors.forename: Sophie
authors.initials: S
authors.lastname: Lissalde
authors.forename: Nicolas
authors.initials: N
authors.lastname: Mazzella
authors.forename: Vincent
authors.initials: V
authors.lastname: Fauvelle
authors.forename: François
authors.initials: F
authors.lastname: Delmas
authors.forename: Patrick
authors.initials: P
authors.lastname: Mazellier
authors.forename: Bernard
authors.initials: B
authors.lastname: Legube
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D010575:Pesticides / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D010575:Pesticides; D014874:Water Pollutants, Chemical