title: [Performances of the Amplified Mycobacterium Tuberculosis Direct Test in non respiratory specimens (study about 1538 samples)].
abstract: From March 1998 to August 2009, 1538 non-respiratory samples collected from 1182 patients, were tested using the Gen-Probe Amplified Mycobacterium Direct Test™ (AMTD). After decontamination procedure, every sample was tested by AMTD and by culture on solid and liquid media. The "Gold-standard" was considered by the combination of culture results and clinical diagnosis. Tuberculosis was present in 17,59 % (208 patients). For theses 1538 non-respiratory samples (225 culture positive samples, 248 AMTD positive), 279 corresponded to tuberculosis. After resolving the discordant results, the sensitivity, specificity, positive and negative values were 89, 99, 99,6 and 97,3 %.
authors.affiliation: Service de biologie médicale, HIA Percy, 101, avenue H.-Barbusse, 92141 Clamart, France. biologie.percy@orange-business.fr
authors.forename: M
authors.initials: M
authors.lastname: Fabre
authors.forename: R
authors.initials: R
authors.lastname: Vong
authors.forename: A
authors.initials: A
authors.lastname: Zrara
authors.forename: P
authors.initials: P
authors.lastname: Saint-Blancard
authors.forename: F
authors.initials: F
authors.lastname: Mechaï
authors.forename: P
authors.initials: P
authors.lastname: Gérome
authors.forename: F
authors.initials: F
authors.lastname: Janvier
authors.forename: A
authors.initials: A
authors.lastname: Boudhas
authors.forename: C
authors.initials: C
authors.lastname: Soler
mesh_terms: D006801:Humans; D066298:In Vitro Techniques; D008853:Microscopy; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques; D009928:Organ Specificity; D011237:Predictive Value of Tests; D012329:RNA, Bacterial / Q000032:analysis*; D012680:Sensitivity and Specificity; D013048:Specimen Handling; D013194:Staining and Labeling; D014376:Tuberculosis / Q000175:diagnosis*
chemical_list: D012329:RNA, Bacterial