title: Single-balloon versus double-balloon endoscopy for achieving total enteroscopy: a randomized, controlled trial.
abstract: BACKGROUND
  Balloon endoscopy has been accepted as an effective tool for examining the small intestine. Two types of balloon endoscopy, single and double, are commercially available. The difference in performance between these 2 types of balloon endoscopy has not yet been elucidated.
  
  
  OBJECTIVE
  To compare the yield of single-balloon endoscopy (SBE) and double-balloon endoscopy (DBE).
  
  
  METHODS
  Single-center, randomized, controlled trial.
  
  
  METHODS
  University hospital in Tokyo, Japan.
  
  
  METHODS
  Patients with suspected small-bowel disease.
  
  
  METHODS
  SBE and DBE.
  
  
  METHODS
  Outcomes were the total enteroscopy rate, diagnostic yield, complication rate, and clinical outcomes. Analysis was done by intent to treat.
  
  
  RESULTS
  The study started in April 2008 and was terminated in April 2010 because of an obvious disadvantage for the SBE group. Thirty-eight patients were enrolled in the study; 18 patients were assigned to the SBE group and 20 to the DBE group. The total enteroscopy rate was 0% in the SBE group and 57.1% in the DBE group (P = .002). In terms of complications, the DBE group had 1 patient with Mallory-Weiss syndrome, and the SBE group had 1 patient with hyperamylasemia. There was no difference in the overall diagnosis rate between the SBE and DBE groups (61.1% vs 50.0%, P = .49). There was no difference in therapeutic outcome between the SBE and DBE groups (27.8% vs 35.0%, P = .63).
  
  
  CONCLUSIONS
  Relatively small number of study patients.
  
  
  CONCLUSIONS
  Total enteroscopy is more easily performed with DBE than with SBE.
authors.affiliation: Department of Gastroenterology and Endoscopy and Endoscopic Surgery, University of Tokyo, Tokyo, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Takano
authors.forename: Atsuo
authors.initials: A
authors.lastname: Yamada
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Watabe
authors.forename: Goichi
authors.initials: G
authors.lastname: Togo
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yamaji
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Yoshida
authors.forename: Takao
authors.initials: T
authors.lastname: Kawabe
authors.forename: Masao
authors.initials: M
authors.lastname: Omata
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Koike
mesh_terms: D002404:Catheterization / Q000379:methods*; D003937:Diagnosis, Differential; D058582:Double-Balloon Enteroscopy / Q000379:methods*; D020776:Endoscopes, Gastrointestinal; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis*; D007421:Intestine, Small; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies