title: Chemical constituents from Astilbe chinensis.
abstract: A new compound, 11-O-(3'-O-methylgalloyl)-bergenin (1), along with 11 known compounds (2-12), has been isolated from the rhizome of Astilbe chinensis. The chemical structure of compound 1 was determined by IR, MS, and NMR spectral data. All compounds were evaluated for the cytotoxic activity in vitro, and compound 4 showed a moderate cytotoxic activity against HepG2 cells.
authors.affiliation: Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Xue
authors.forename: Xue-Min
authors.initials: XM
authors.lastname: Xu
authors.forename: Ju-Fang
authors.initials: JF
authors.lastname: Yan
authors.forename: Wen-Long
authors.initials: WL
authors.lastname: Deng
authors.forename: Xun
authors.initials: X
authors.lastname: Liao
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D031995:Saxifragaceae / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: C556176:11-O-(3'-methylgalloyl)bergenin; C556177:3-hydroxyolean-12-en-27-oic acid; D000972:Antineoplastic Agents, Phytogenic; D001578:Benzopyrans; D004365:Drugs, Chinese Herbal; D005707:Gallic Acid; D009828:Oleanolic Acid