title: Scandium(III) zeolites as new heterogeneous catalysts: [4+2]cyclocondensation of in situ generated aryl imines with alkenes.
abstract: Scandium(III)-exchanged zeolite was used as heterogeneous ligand-free catalysts for the [4+2]cyclocondensation of amines and aldehydes with alkenes through the in situ formation of imines. Such catalysts offered a versatile, efficient, and highly regio- and stereoselective synthesis of tetrahydroquinoline derivatives. These catalysts exhibited a wide scope and compatibility with functional groups. They are very simple to use, easy to remove (by simple filtration), and they are recyclable (up to three times without loss of activity).
authors.affiliation: Laboratoire de Synthèse et Réactivité Organiques, Institut de Chimie de Strasbourg, associé au CNRS, 4 rue Blaise Pascal, 67000 Strasbourg, France.
authors.forename: Andrea
authors.initials: A
authors.lastname: Olmos
authors.forename: Jean
authors.initials: J
authors.lastname: Sommer
authors.forename: Patrick
authors.initials: P
authors.lastname: Pale
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D012538:Scandium / Q000737:chemistry*; D013237:Stereoisomerism; D017641:Zeolites / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000475:Alkenes; D000588:Amines; D007097:Imines; D011804:Quinolines; D017641:Zeolites; D012538:Scandium