title: Personality traits and the amplitude of spontaneous low-frequency oscillations during resting state.
abstract: Recently, neural substrates of the Big Five personality model were investigated using neuroimaging. We examined the relationships between the amplitude of spontaneous low-frequency oscillations (LFO) and the Big Five traits using resting-state functional magnetic resonance imaging (R-fMRI). Twenty-four healthy right-handed undergraduates (23.13±1.87 years, 9 males and 15 females) participated in 5-min R-fMRI and completed the NEO Five-Factor Inventory. We observed that Neuroticism correlated negatively with regional activity of the middle frontal gyrus and precuneus; Extraversion correlated positively with regional activity of the striatum, precuneus, and superior frontal gyrus; Openness correlated positively with the thalamus and amygdala, and negatively with the superior frontal gyrus; Conscientiousness correlated positively with regional activity of the middle frontal gyrus and correlated negatively with the cerebellum. Our results revealed the neural substrates of Extraversion, Neuroticism, Openness, and Conscientiousness in the amplitude of spontaneous LFO.
authors.affiliation: Department of Psychiatry and Neurosciences, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kunisato
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Go
authors.initials: G
authors.lastname: Okada
authors.forename: Shiori
authors.initials: S
authors.lastname: Aoyama
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Nishiyama
authors.forename: Keiichi
authors.initials: K
authors.lastname: Onoda
authors.forename: Shigeto
authors.initials: S
authors.lastname: Yamawaki
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D005120:Extraversion, Psychological; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010100:Oxygen / Q000097:blood; D010551:Personality / Q000502:physiology*; D010555:Personality Inventory; D012146:Rest / Q000502:physiology*; D013223:Statistics as Topic; D055815:Young Adult
chemical_list: D010100:Oxygen