title: The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.
authors.forename: C
authors.initials: C
authors.lastname: Haferlach
authors.forename: U
authors.initials: U
authors.lastname: Bacher
authors.forename: T
authors.initials: T
authors.lastname: Haferlach
authors.forename: F
authors.initials: F
authors.lastname: Dicker
authors.forename: T
authors.initials: T
authors.lastname: Alpermann
authors.forename: W
authors.initials: W
authors.lastname: Kern
authors.forename: S
authors.initials: S
authors.lastname: Schnittger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D007446:Chromosome Inversion; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D005260:Female; D011905:Genes, ras / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D025542:Neurofibromin 1 / Q000235:genetics*; D011379:Prognosis; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D015996:Survival Rate; D014178:Translocation, Genetic / Q000235:genetics*; D055815:Young Adult; D018631:ras Proteins / Q000235:genetics*
chemical_list: D050676:Core Binding Factor Alpha 2 Subunit; C117307:KRAS protein, human; D025542:Neurofibromin 1; D011518:Proto-Oncogene Proteins; C493728:RUNX1 protein, human; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins