title: [Diabetic amyotrophy: favorable outcome following corticosteroid therapy?].
abstract: Diabetic amyotrophy or lombosacral radiculoplexus neuropathy is a rare complication associated with early-stage diabetes. Thigh pain, quadricipital amyotrophy, proximal weakness of lower limbs and weight loss are the main symptoms of the disease. As neurological damage is related to inflammatory microvasculitis, corticosteroid therapy may be considered as the first line therapy. We report a 54-year-old patient with type 2 diabetes affected with severe diabetic amyotrophy. Following intravenous corticosteroid therapy, the patient reported a rapid pain relief and gained muscle strength.
authors.affiliation: Service de médecine interne et nutrition, hôpital Bretonneau, CHRU de Tours, France.
authors.forename: M
authors.initials: M
authors.lastname: Jaspard
authors.forename: D
authors.initials: D
authors.lastname: Jacobi
authors.forename: J
authors.initials: J
authors.lastname: Praline
authors.forename: J
authors.initials: J
authors.lastname: Magnant
authors.forename: R
authors.initials: R
authors.lastname: Buzelé
authors.forename: C
authors.initials: C
authors.lastname: Couet
authors.forename: F
authors.initials: F
authors.lastname: Maillot
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy; D003929:Diabetic Neuropathies / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008160:Lumbosacral Plexus / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011128:Polyradiculopathy / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D008775:Methylprednisolone