title: In vitro fertilization outcomes in patients experiencing a premature rise in luteinizing hormone during a gonadotropin-releasing hormone antagonist cycle.
abstract: Patients undergoing controlled ovarian hyperstimulation and pituitary suppression with a GnRH antagonist who experienced a transient premature rise in LH were compared with those who did not have an early surge. Those experiencing a premature LH surge had equivalent clinical and ongoing pregnancy rates per ET.
authors.affiliation: The Center for Advanced Reproductive Services, Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Farmington, Connecticut 06030-6224, USA.
authors.forename: Nicole E
authors.initials: NE
authors.lastname: Kummer
authors.forename: Vanessa N
authors.initials: VN
authors.lastname: Weitzman
authors.forename: Claudio A
authors.initials: CA
authors.lastname: Benadiva
authors.forename: David W
authors.initials: DW
authors.lastname: Schmidt
authors.forename: Lawrence L
authors.initials: LL
authors.lastname: Engmann
authors.forename: John C
authors.initials: JC
authors.lastname: Nulsen
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D004334:Drug Administration Schedule; D005260:Female; D005300:Fertility Agents, Female / Q000008:administration & dosage*; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors*; D006727:Hormone Antagonists / Q000008:administration & dosage*; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D007986:Luteinizing Hormone / Q000097:blood*; D010060:Ovulation / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D005300:Fertility Agents, Female; D006727:Hormone Antagonists; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; C061018:ganirelix