title: [Bloodstream infection in a neonatology unit of Medellín-Colombia, 2008-2009].
abstract: Bloodstream infection (BSI) is one of the main causes of sepsis and death in newborns. The relative importance of nosocomial and non-nosocomial agents in developing countries is not clear. We conducted a prospective study of newborns hospitalized with a first episode of BSI in order to classify it as early, late or nosocomial, describe the clinical and microbiological characteristics, and explore risk factors between hospital-acquired vs community-acquired BSI (HA-BSI vs CA-BSI). Twenty-seven newborns with a first episode of BSI were identified. Streptococcus agalactiae and coagulase negative Staphylococcus were the main agents in CA-BSI and HA-BSI, respectively. The only significant intrinsic risk factor between HA-BSI and CA-BSI was gestational age. The frequent finding of S. agalactiae warrants routine screening and prophylaxis in pregnant women. The risk factors for HA-BSI were mostly extrinsic, and thus, susceptible of being modified.
authors.affiliation: Clínica Universitaria Bolivariana, Medellín, Colombia. alvaromicro@hotmail.com
authors.forename: Alvaro
authors.initials: A
authors.lastname: Hoyos O
authors.forename: Margarita
authors.initials: M
authors.lastname: Suarez G
authors.forename: Mónica
authors.initials: M
authors.lastname: Massaro C
authors.forename: Gloría
authors.initials: G
authors.lastname: Ortiz M
authors.forename: José
authors.initials: J
authors.lastname: Aguirre C
authors.forename: Andrés
authors.initials: A
authors.lastname: Uribe M
mesh_terms: D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D003105:Colombia / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009359:Neonatology; D011446:Prospective Studies; D012307:Risk Factors