title: Prohibitin(g) cancer: aurilide and killing by Opa1-dependent cristae remodeling.
abstract: Proapoptotic drugs targeting the mitochondrial Bcl-2 rheostat of apoptosis are tools to selectively kill cancer cells. Sato et al. (2011) expand the available toolkit by identifying the target of the cytotoxic natural product aurilide in the prohibitin Opa1-dependent apoptotic cristae remodeling.
authors.affiliation: Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Via Orus 2, 35129 Padova, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Semenzato
authors.forename: Sara
authors.initials: S
authors.lastname: Cogliati
authors.forename: Luca
authors.initials: L
authors.lastname: Scorrano