title: The use of hypnosedative drugs in a university hospital: has anything changed in 10 years?
abstract: OBJECTIVE
  Our goal was to investigate the use of hypnosedatives (HSs) before and during hospitalization, explore the relationship between their use and various demographic and clinical variables, and compare the results with data from a similar 2000 study with particular interest in adherence to hospital formulary guidelines.
  
  
  METHODS
  A cross-sectional observational survey of 326 hospitalized patients recruited from ten wards of the Ghent University Hospital, Gent, Belgium, with a patient interview and by evaluating medical and nursing files.
  
  
  RESULTS
  In 30.7% of patients, the use of a HS before admission was reported. According to the patient interview, 33.1% used a HS during hospitalization. However, according to medical and nursing files, use of HSs in the hospital was 10% higher (43.3%). In 19.4% of patients who took HSs before admission, their use was discontinued in the hospital. In 15.6% of patients who took no HS before admission, a HS was started in the hospital, according to the formulary guidelines (data from files). There was a positive correlation between HS use in the hospital and older age, longer hospitalization, not coming from home, higher number of HSs taken before hospitalization, sleeping problems emerging during hospitalization, and central nervous system (CNS) disorders. In comparison with 2000, we registered a slight decrease in HS use during hospitalization and a decrease in the number of newly started patients.
  
  
  CONCLUSIONS
  The prevalence of HS use in our university hospital is high, mostly as a result of continuation of HSs started before admission, as there seems to be no general policy of active cessation. Compared with the survey performed 10 years ago, fewer hospitalized patients are newly started on HSs, and when this is the case, the formulary guidelines are followed.
authors.affiliation: Department of Pharmacy, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium. annemie.somers@uzgent.be
authors.forename: Annemie
authors.initials: A
authors.lastname: Somers
authors.forename: Hugo
authors.initials: H
authors.lastname: Robays
authors.forename: Kurt
authors.initials: K
authors.lastname: Audenaert
authors.forename: Georges
authors.initials: G
authors.lastname: Van Maele
authors.forename: Marc
authors.initials: M
authors.lastname: Bogaert
authors.forename: Mirko
authors.initials: M
authors.lastname: Petrovic
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001007:Anxiety / Q000188:drug therapy*; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011446:Prospective Studies; D018570:Risk Assessment; D012893:Sleep Wake Disorders / Q000188:drug therapy*; D019966:Substance-Related Disorders / Q000517:prevention & control; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D006993:Hypnotics and Sedatives