title: Differences in patient outcomes and chronic care management of oral anticoagulant therapy: an explorative study.
abstract: BACKGROUND
  The oral anticoagulant therapy - provided to prevent thrombosis - is known to be associated with substantial avoidable hospitalization. Improving the quality of the oral anticoagulant therapy could avoid drug related hospitalizations. Therefore, this study compared the patient outcomes between Dutch anticoagulant clinic (AC) regions taking the variation in chronic care management into account in order to explore whether chronic care management elements could improve the quality of oral anticoagulant therapy.
  
  
  METHODS
  Two data sources were combined. The first source was a questionnaire that was send to all ACs in the Netherlands in 2008 (response = 100%) to identify the application of chronic care management elements in the AC regions. The Chronic Care Model of Wagner was used to make the concept of chronic care management operational. The second source was the report of the Dutch National Network of ACs which contains patient outcomes of the ACs.
  
  
  RESULTS
  Patient outcomes achieved by the ACs were good, yet differences existed; for instance the percentage of patients in the appropriate therapeutic ranges varied from 67 to 87% between AC regions. Moreover, differences existed in the use of chronic care management elements of the chronic care model, for example 12% of the ACs had multidisciplinary meetings and 58% of the ACs had formal agreements with at least one hospital within their region. Patient outcomes were significantly associated with patient orientation and the number of specialized nurses versus doctors (p-values < 0.05). Furthermore, the overall extent to which chronic care management elements were applied was positively associated with patient outcomes (p-values < 0.05).
  
  
  CONCLUSIONS
  Substantial differences in the patient outcomes as well as chronic care management of oral anticoagulant therapy existed. Since our results showed a positive association between overall application of chronic care management and patient outcomes, additional research is needed to fully understand the working mechanism of chronic care management.
authors.affiliation: TRANZO, Tilburg University, Tilburg, The Netherlands. hanneke.drewes@rivm.nl
authors.forename: Hanneke W
authors.initials: HW
authors.lastname: Drewes
authors.forename: Mattijs S
authors.initials: MS
authors.lastname: Lambooij
authors.forename: Caroline A
authors.initials: CA
authors.lastname: Baan
authors.forename: Bert R
authors.initials: BR
authors.lastname: Meijboom
authors.forename: Wilco C
authors.initials: WC
authors.lastname: Graafmans
authors.forename: Gert P
authors.initials: GP
authors.lastname: Westert
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage*; D002908:Chronic Disease / Q000188:drug therapy; D003430:Cross-Sectional Studies; D006801:Humans; D009426:Netherlands; D017063:Outcome Assessment, Health Care / Q000379:methods; D010346:Patient Care Management / Q000592:standards; D011785:Quality Assurance, Health Care; D011787:Quality of Health Care / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D013927:Thrombosis / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants