title: Study on the drug selection law for treatment of chronic gastritis with spleen deficiency and stomach dryness by complex system entropy cluster.
abstract: OBJECTIVE
  To study on Prof. GAO Zhong-ying's drug selection law for treatment of chronic gastritis with data mining technique.
  
  
  METHODS
  The 407 medical records of chronic gastritis treated by Prof. GAO Zhong-ying were collected and the study on these drugs in the recipes was carried out with data mining method. Among them, the recipe composed of one drug was studied with frequency statistical method, correlativity between drug pairs with improved mutual information, correlativity among multi-drugs with complex system entropy cluster technique.
  
  
  RESULTS
  In treatment of chronic gastritis by Prof. GAO Zhong-ying there were 30 drugs with a higher use frequency of over 38 times, 94 commonly-used drug pairs with correlation coefficient of over 0.05, 11 commonly-used drug core combinations.
  
  
  CONCLUSIONS
  The results attained with data mining technique for studying experience of famous and old TCM physicians conform to the clinical practice and the method is of an important significance for summarization of famous and old TCM physicians' experiences.
authors.affiliation: Section of Traditional Chinese Medicine, Third Hospital, Peking University, Beijing 100191, China.
authors.forename: Cheng-He
authors.initials: CH
authors.lastname: Shi
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Wang
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Chen
authors.forename: Ren-Quan
authors.initials: RQ
authors.lastname: Liu
authors.forename: Yu-Hao
authors.initials: YH
authors.lastname: Zhao
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Yang
mesh_terms: D002626:Chemistry, Pharmaceutical; D002908:Chronic Disease / Q000628:therapy; D057225:Data Mining; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000627:therapeutic use; D005756:Gastritis / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D013154:Spleen / Q000503:physiopathology*; D013270:Stomach / Q000503:physiopathology*
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal