title: Structural MRI in autism spectrum disorder.
abstract: Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD). We review recent advances in the understanding of structural MR correlates of ASD. We summarize findings from studies based on voxel-based morphometry, surface-based morphometry, tensor-based morphometry, and diffusion-tensor imaging. Finally, we discuss diagnostic models of ASD based on MR-derived features.
authors.affiliation: Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. rong.chen@uphs.upenn.edu
authors.forename: Rong
authors.initials: R
authors.lastname: Chen
authors.forename: Yun
authors.initials: Y
authors.lastname: Jiao
authors.forename: Edward H
authors.initials: EH
authors.lastname: Herskovits
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male