title: [Empirical antibiotic therapy of complicated skin and soft tissue infections in dermatological practice].
abstract: Erysipelas is an acute bacterial infection of the skin predominantly caused by Streptococcus pyogenes. According to the international classification complicated erysipelas belongs to the complicated skin and soft tissue infections. Complicated infections are defined as severe skin involvement or when the infection occurs in compromised hosts. These infections frequently involve Gram-negative bacilli and anaerobic bacteria.
  
  
  OBJECTIVE
  The aim of this study was to compare the efficacy of the empirical antibiotic therapy for the patients who were admitted to the Department of Dermatology and Allergology, University of Szeged.
  
  
  METHODS
  The empirical therapy was started according to a previously determined protocol. The data of 158 patients with complicated skin and soft tissue infections were analyzed and the microbiology culture specimens and the isolates were also examined.
  
  
  CONCLUSIONS
  The results show that penicillin is the first choice for the treatment of erysipelas. However, the complicated skin and soft tissue infections require broad-spectrum antibiotics.
authors.affiliation: Szegedi Tudományegyetem, Általános Orvostudományi Kar, Bőrgyógyászati és Allergológiai Klinika, Szeged.
authors.forename: Andrea
authors.initials: A
authors.lastname: Magyar
authors.forename: Edina
authors.initials: E
authors.lastname: Garaczi
authors.forename: Edit
authors.initials: E
authors.lastname: Hajdú
authors.forename: Lajos
authors.initials: L
authors.lastname: Kemény
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D048909:Diabetes Complications / Q000188:drug therapy / Q000382:microbiology; D004886:Erysipelas / Q000188:drug therapy / Q000382:microbiology; D005145:Face / Q000382:microbiology; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006760:Hospitalization; D006801:Humans; D006814:Hungary; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis / Q000382:microbiology; D010406:Penicillins / Q000627:therapeutic use*; D017192:Skin Diseases, Bacterial / Q000188:drug therapy* / Q000382:microbiology*; D018461:Soft Tissue Infections / Q000188:drug therapy* / Q000382:microbiology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins