title: New model for surgical and nonsurgical therapy in adults with Class III malocclusion.
abstract: BACKGROUND
  Not all adult Class III malocclusion patients are candidates for surgical correction. In patient assessment and selection, major issues remain regarding diagnosis and treatment planning. The purpose of this investigation was to ascertain whether adding a transverse parameter to a discriminant analysis could improve the classification of adults with Class III malocclusion into 2 groups of patients: those who can effectively be treated by orthodontic therapy and those who require orthognathic surgery.
  
  
  METHODS
  Cephalograms, plaster casts, and extraoral photos of 69 adults with Class III malocclusion were analyzed. A discriminant analysis was performed to identify the variables that best separate the 2 groups.
  
  
  RESULTS
  Stepwise variable selection resulted in a new, highly significant (P <0.0001) model of 4 variables that provided the best discriminant function to distinguish between patients with and without indications for surgical correction. The resulting equation was the following: score = -10.988 + 0.243 * Wits + 0.055 * M/M ratio + 0.068 * NSAr - 0.589 * mand MLD. The percentage of patients correctly classified by this equation was 91.3%. The sensitivity was 0.92, and the specificity was 0.89.
  
  
  CONCLUSIONS
  In the discriminant analysis, the mandibular midline deviation as a transverse component was included. The addition of the transverse variable led to an improved model concerning the predictive value in Class III malocclusion patients with surgical requirements.
authors.affiliation: Department of Orthodontics, Dental Clinic, Medical Faculty of the University of Wuerzburg, Wuerzburg, Germany. kochel_j@klinik.uni-wuerzburg.de
authors.forename: Janka
authors.initials: J
authors.lastname: Kochel
authors.forename: Stefanie
authors.initials: S
authors.lastname: Emmerich
authors.forename: Philipp
authors.initials: P
authors.lastname: Meyer-Marcotty
authors.forename: Angelika
authors.initials: A
authors.lastname: Stellzig-Eisenhauer
mesh_terms: D000293:Adolescent; D000328:Adult; D002508:Cephalometry / Q000145:classification*; D016002:Discriminant Analysis; D005146:Facial Asymmetry / Q000473:pathology; D006801:Humans; D008313:Malocclusion, Angle Class III / Q000145:classification* / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008334:Mandible; D008875:Middle Aged; D015233:Models, Statistical; D009971:Orthodontics, Corrective; D056948:Orthognathic Surgical Procedures; D010347:Patient Care Planning; D018579:Patient Selection; D011237:Predictive Value of Tests; D011859:Radiography; D019291:Skull Base / Q000033:anatomy & histology; D018709:Statistics, Nonparametric; D055815:Young Adult