title: Non-mosaic Klinefelter syndrome and successful testicular sperm extraction-intracytoplasmic sperm injection procedure: case report.
abstract: BACKGROUND
  Klinefelter syndrome is the commonest chromosomal cause of non-obstructive azoospermia. Despite reports that these men can have children using assisted reproduction techniques, it is not common practice in the Egypt to offer sperm retrieval to these men.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Private IVF center (EIFC-IVF) and a university hospital.
  
  
  METHODS
  A 24-year-old woman and a 29-year-old man with non-mosaic Klinefelter syndrome.
  
  
  METHODS
  Testicular sperm extraction followed by intracytoplasmic sperm injection and embryo transfer (TESE-ICSI).
  
  
  RESULTS
  Fifteen immotile sperms were found, five oocytes were injected, and three embryos were transferred. Now the pregnancy is progressing beyond 20 weeks.
  
  
  CONCLUSIONS
  Spermatozoa from a patient with non-mosaic Klinefelter syndrome retrieved through TESE can lead to pregnancy.
authors.affiliation: Faculty of Medicine, Department of Obstetrics and Gynecology, Cairo University, Cairo, Egypt.
authors.forename: Ismail I
authors.initials: II
authors.lastname: Aboulfotouh
authors.forename: Mohamed A F
authors.initials: MA
authors.lastname: Youssef
authors.forename: Amir F
authors.initials: AF
authors.lastname: Mady
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Abdelhak
authors.forename: Sherif M
authors.initials: SM
authors.lastname: Khattab
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007713:Klinefelter Syndrome; D008297:Male; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa; D013737:Testis / Q000166:cytology*; D055815:Young Adult