title: Hypokalaemic paralysis secondary to distal renal tubular acidosis as the presenting symptom of systemic lupus erythematosus.
abstract: We report hypokalaemic quadriparesis presenting in a 43-year-old woman. Evaluation revealed hypokalaemic quadriparesis secondary to underlying distal renal tubular acidosis, also known as type 1 RTA. Four years after the diagnosis of RTA, the patient developed joint pain, and investigation revealed systemic lupus erythematosus with lupus nephritis. RTA is one of the very rare presentations of systemic lupus erythematosus. Thus, tubular dysfunction should be carefully assessed in patients with systemic lupus erythematosus. Similarly, patients with RTA should be evaluated for underlying lupus. Our patient was successfully treated with mycophenolate mofetil and steroids.
authors.affiliation: Department of Medicine, Christian Medical College and Hospital, Ludhiana 141008, Punjab, India. cgera@rediffmail.com
authors.forename: C
authors.initials: C
authors.lastname: Gera
authors.forename: D
authors.initials: D
authors.lastname: Mohapatra
authors.forename: N
authors.initials: N
authors.lastname: Calton
mesh_terms: D000141:Acidosis, Renal Tubular / Q000150:complications* / Q000473:pathology; D000208:Acute Disease; D000328:Adult; D001799:Blood Sedimentation; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology; D009132:Muscles / Q000473:pathology; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D010243:Paralysis / Q000150:complications* / Q000473:pathology; D011507:Proteinuria / Q000150:complications; D013256:Steroids / Q000494:pharmacology; D016896:Treatment Outcome
chemical_list: D013256:Steroids; D009173:Mycophenolic Acid