title: Impact of measuring multiple or single occlusal lesions on estimates of diagnostic accuracy using fluorescence methods.
abstract: Carious lesions can occur at different sites on the occlusal surfaces of teeth and may differ in appearance and severity. This study aimed to evaluate how scoring several lesions on occlusal surfaces, as opposed to only one representative lesion, affects estimates of reproducibility and accuracy of fluorescence-based devices. Thirty-six permanent teeth with 2-3 investigation sites (n = 82) were examined by two examiners using the laser fluorescence device DIAGNOdent pen (LF) and the fluorescence camera VistaProof (FC). Lesion depth was then assessed histologically in serial sections of the teeth. Intra-class-correlation coefficients (ICC) and areas under the ROC-curves were calculated for all investigation sites and for one randomly selected site per tooth. Comparing the reproducibility and the performance for the whole sample and the independent sites showed only a small effect or no effect. Measuring multiple sites on teeth with fluorescence devices only moderately influences performance compared to one site being investigated.
authors.affiliation: Department of Paediatric and Community Dentistry, Dental School, Philipps-University of Marburg, Georg-Voigt-Str. 3, 35033, Marburg, Germany. momeni@staff.uni-marburg.de
authors.forename: Anahita
authors.initials: A
authors.lastname: Jablonski-Momeni
authors.forename: Simon M
authors.initials: SM
authors.lastname: Rosen
authors.forename: Helge M
authors.initials: HM
authors.lastname: Schipper
authors.forename: Richard
authors.initials: R
authors.lastname: Stoll
authors.forename: Matthias J
authors.initials: MJ
authors.lastname: Roggendorf
authors.forename: Monika
authors.initials: M
authors.lastname: Heinzel-Gutenbrunner
authors.forename: Vitus
authors.initials: V
authors.lastname: Stachniss
authors.forename: Klaus
authors.initials: K
authors.lastname: Pieper
mesh_terms: D019540:Area Under Curve; D003731:Dental Caries / Q000473:pathology*; D005453:Fluorescence; D006801:Humans; D008963:Molar / Q000473:pathology*; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019217:Tooth Attrition / Q000473:pathology*