title: Novel method of intralesional cidofovir injection into laryngotracheal papillomata.
abstract: Laryngeal papillomatosis is characterised by multiple papillomata affecting the upper respiratory tract. This condition is difficult to treat due to its recurrent nature. Treatment often involves surgical debulking. A number of non-surgical treatments have been reported. Intralesional cidofovir, a cytosine nucleoside analogue with antiviral activity, has been used in an attempt to manage the condition. We present a novel technique of administering cidofovir in a case of recurrent laryngotracheal papillomata.
authors.affiliation: Department of Otorhinolaryngology, Leicester Royal Infirmary, UK. rss8@le.ac.uk
authors.forename: R S
authors.initials: RS
authors.lastname: Sahota
authors.forename: F J
authors.initials: FJ
authors.lastname: Uddin
authors.forename: J
authors.initials: J
authors.lastname: Al-Shukri
authors.forename: A A
authors.initials: AA
authors.lastname: Moir
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001999:Bronchoscopy; D000077404:Cidofovir; D003596:Cytosine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015552:Injections, Intralesional / Q000295:instrumentation / Q000379:methods; D007822:Laryngeal Neoplasms / Q000188:drug therapy; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D063065:Organophosphonates / Q000008:administration & dosage* / Q000627:therapeutic use; D010212:Papilloma / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; D003596:Cytosine; D000077404:Cidofovir