title: Wound closure sutures and needles: a new perspective.
abstract: Ideally, the choice of the suture material should be based on the biological interaction of the materials employed, the tissue configuration, and the biomechanical properties of the wound. Measurements of the in vivo degradation of sutures separate them into two general classes: absorbable and nonabsorbable sutures. The nonabsorbable sutures and absorbable sutures are classified according to their origin. When considering an absorbable suture's tensile strength in vivo, we recommend that the manufacturer provides specific recommendations of its holding strength, rather than the percentage retained of its initial tensile strength. The newest advance in nonabsorbable sutures is polybutester suture, which is a block copolymer that contains butylene terephthalate (84%) and polytetramethylene ether glycol terephthalate (16%). The expanded polytetrafluoroethylene (ePTFE) suture has been expanded to produce a porous microstructure that is approximately 50% air by volume. The clinical performance of polybutester suture has been enhanced by coating its surface with a unique absorbable polymer. A search for a synthetic substitute for absorbable collagen sutures led to the development of the POLYSORB™ sutures that can reliably approximate tissues with a low risk for infection. The latest innovation in the development of monofilament absorbable sutures has been in the rapidly absorbing CAPROSYN™ suture. A new high-nickel stainless steel, SURGALLOY™, has been used recently to manufacture surgical needles. Biomechanical performance studies of cutting edge needles made of S45500 stainless steel alloy and SURGALLOY™ stainless steel demonstrated that needles made of SURGALLOY™ had superior performance characteristics over those made of S45500.
authors.affiliation: Biomedical Engineering and Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA. richardedlich@gmail.com
authors.forename: Richard F
authors.initials: RF
authors.lastname: Edlich
authors.forename: K
authors.initials: K
authors.lastname: Gubler
authors.forename: Anne G
authors.initials: AG
authors.lastname: Wallis
authors.forename: Jamie J
authors.initials: JJ
authors.lastname: Clark
authors.forename: Jill J
authors.initials: JJ
authors.lastname: Dahlstrom
authors.forename: William B
authors.initials: WB
authors.lastname: Long
mesh_terms: D006801:Humans; D009339:Needles; D010818:Practice Patterns, Physicians'; D013537:Sutures; D014947:Wounds and Injuries / Q000601:surgery*