title: "Sarcoid like" granulomatous pulmonary disease in World Trade Center disaster responders.
abstract: BACKGROUND
  More than 20,000 responders have been examined through the World Trade Center (WTC) Medical Monitoring and Treatment Program since September 11, 2001. Studies on WTC firefighters have shown elevated rates of sarcoidosis. The main objective of this study was to report the incidence of "sarcoid like" granulomatous pulmonary disease in other WTC responders.
  
  
  METHODS
  Cases of sarcoid like granulomatous pulmonary disease were identified by: patient self-report, physician report and ICD-9 codes. Each case was evaluated by three pulmonologists using the ACCESS criteria and only "definite" cases are reported.
  
  
  RESULTS
  Thirty-eight patients were classified as "definite" cases. Six-year incidence was 192/100,000. The peak annual incidence of 54 per 100,000 person-years occurred between 9/11/2003 and 9/11/2004. Incidence in black responders was nearly double that of white responders. Low FVC was the most common spirometric abnormality.
  
  
  CONCLUSIONS
  Sarcoid like granulomatous pulmonary disease is present among the WTC responders. While the incidence is lower than that reported among firefighters, it is higher than expected.
authors.affiliation: Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. laura.crowley@mssm.edu
authors.forename: Laura E
authors.initials: LE
authors.lastname: Crowley
authors.forename: Robin
authors.initials: R
authors.lastname: Herbert
authors.forename: Jacqueline M
authors.initials: JM
authors.lastname: Moline
authors.forename: Sylvan
authors.initials: S
authors.lastname: Wallenstein
authors.forename: Gauri
authors.initials: G
authors.lastname: Shukla
authors.forename: Clyde
authors.initials: C
authors.lastname: Schechter
authors.forename: Gwen S
authors.initials: GS
authors.lastname: Skloot
authors.forename: Iris
authors.initials: I
authors.lastname: Udasin
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Luft
authors.forename: Denise
authors.initials: D
authors.lastname: Harrison
authors.forename: Moshe
authors.initials: M
authors.lastname: Shapiro
authors.forename: Karen
authors.initials: K
authors.lastname: Wong
authors.forename: Henry S
authors.initials: HS
authors.lastname: Sacks
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Landrigan
authors.forename: Alvin S
authors.initials: AS
authors.lastname: Teirstein
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008168:Lung / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D016273:Occupational Exposure / Q000009:adverse effects*; D018635:Rescue Work; D012129:Respiratory Function Tests; D012307:Risk Factors; D017565:Sarcoidosis, Pulmonary / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D047851:September 11 Terrorist Attacks / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D055815:Young Adult