title: Uncovering the global host cell requirements for influenza virus replication via RNAi screening.
abstract: Influenza virus is reliant on numerous host cell functions during its replication cycle. RNA interference technology, applied on a genome-wide level, has identified human host factors that are necessary for efficient virus replication and provides new insight into how influenza virus interacts with its host at the molecular level.
authors.affiliation: Department of Microbiology, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.
authors.forename: Silke
authors.initials: S
authors.lastname: Stertz
authors.forename: Megan L
authors.initials: ML
authors.lastname: Shaw
mesh_terms: D000818:Animals; D002460:Cell Line; D054884:Host-Pathogen Interactions; D006801:Humans; D051379:Mice; D009975:Orthomyxoviridae / Q000235:genetics / Q000502:physiology*; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D034622:RNA Interference; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D014779:Virus Replication
chemical_list: D011506:Proteins; D014764:Viral Proteins