title: HIV-1 incidence estimates among young Thai men using IgG-capture BED-enzyme immunoassay (BED-CEIA) during 2005-2006.
abstract: BACKGROUND
  Knowledge about the most recent HIV epidemic among young generation in Thailand is crucial for improving the prevention programs. It is important to distinguish between recent and long-term HIV-1 infections among the sero-surveillance populations to estimate the HIV-1 incidence.
  
  
  OBJECTIVE
  To obtain the HIV-1 incidence estimates in young Thai men from the HIV-1 sero-surveillance among the Royal Thai Army (RTA) conscripts inducted between November 2005 and November 2006.
  
  
  METHODS
  The confirmed HIV-1 positive serum samples obtained from the November 2005, May 2006, and November 2006 rounds of RTA conscripts induction were selected to be included in the study. The recent HIV-1 infections were detected among the confirmed HIV-1 positive serum samples using an HIV-1 BED incidence EIA Kit (Calypte HIV-1 BED Incidence EIA, Calypte Biomedical Corporation, Maryland, USA. The incidence estimates were obtained in each round of the induction using a consensus formula was agreed upon at the US Centers for Disease Controls and Preventions (CDC).
  
  
  RESULTS
  Eighty seven thousand one hundred seventy eight RTA conscripts were tested for HIV-1 infection between November 2005 and November 2006. The prevalence of HIV-1 infection was 0.51%, 0.60%, and 0.50% for the period of November 2005, May 2006, and November 2006, respectively. The HIV-1 incidence estimates were 0.14%/year (95% CI, 0.09-0.20), 0.20% year (95% CI, 0.13-0.28), and 0.17%/year (95% CI, 0.10-0.29) in November 2005, May 2006, and November 2006, respectively.
  
  
  CONCLUSIONS
  We reported the HIV-1 incidence estimates obtained from the IgG-capture BED-enzyme immunoassay (BED-CEIA) method in the RTA conscripts sero-surveillance population. The incidence estimates were ranging from 0.14% - 0.20%/year between November 2005 and November 2006. The estimates could serve as the recent baseline information for future HIV prevention interventions in Thailand.
authors.affiliation: Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand. k_khunakorn@hotmail.com
authors.forename: Khunakorn
authors.initials: K
authors.lastname: Kana
authors.forename: Sutchana
authors.initials: S
authors.lastname: Tabprasit
authors.forename: Thippawan
authors.initials: T
authors.lastname: Chuenchitra
authors.forename: Narongrid
authors.initials: N
authors.lastname: Sirisopana
authors.forename: Ram
authors.initials: R
authors.lastname: Rangsin
mesh_terms: D044466:Asian People; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology*; D006679:HIV Seropositivity / Q000453:epidemiology*; D015528:HIV Seroprevalence; D015497:HIV-1 / Q000145:classification / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007074:Immunoglobulin G / Q000276:immunology; D015994:Incidence; D008297:Male; D008889:Military Personnel; D011159:Population Surveillance; D013785:Thailand / Q000453:epidemiology; D055815:Young Adult
chemical_list: D015483:HIV Antibodies; D007074:Immunoglobulin G