title: Purification and identification of carvacrol from the root of Stellera chamaejasme and research on its insecticidal activity.
abstract: The root powder of Stellera chamaejasme was extracted with petroleum ether. The crude extract obtained was chromatographed repeatedly with silica gel columns. One pure natural product was obtained, which was identified as 5-isopropyl-2-methylphenol (carvacrol), separated for the first time from the root of S. chamaejasme. The results of a laboratory bioassay showed that it had good insecticidal activity against Aphis craccivora and Leucania separata. Its median lethal concentrations (LC(50)) (24 h after treatment) were 16.8 and 12.7 mg L(-1), respectively. This is the first report of the insecticidal activity of carvacrol against A. craccivora and L. separata.
authors.affiliation: College of Physics and Chemistry, Xihua University, Chengdu 610039, PR China. tangxiaorong0901@163.com
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Tang
authors.forename: Shaoling
authors.initials: S
authors.lastname: Chen
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
mesh_terms: D000818:Animals; D001042:Aphids / Q000187:drug effects; D000081007:Cymenes; D007313:Insecta / Q000187:drug effects; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D029645:Thymelaeaceae / Q000737:chemistry*
chemical_list: D000081007:Cymenes; D007306:Insecticides; D039821:Monoterpenes; C073316:carvacrol