title: Photopatterning of cell-adhesive-modified poly(ethyleneimine) for guided neuronal growth.
abstract: We describe photopatterning technique that employs the photodegradation of cell-adhesive-modified poly(ethyleneimine) (m-PEI) to fabricate precise micropatterns on the indium tin oxide (ITO) substrate for guided neuronal growth. The photodegradation of m-PEI coated on hydroxyl group-terminated ITO substrate created micropatterns over a large area through deep UV irradiation. The photopatterned m-PEI layer can effectively guide neurite outgrowth and control neurite extensions from individual neurons.
authors.affiliation: IT Convergence Technology Research Laboratory, Electronics and Telecommunications Research Institute , 138 Gajeongno, Yuseong-gu, Daejeon 305-700, Republic of Korea.
authors.forename: Nam Seob
authors.initials: NS
authors.lastname: Baek
authors.forename: Ji-Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Yong Hee
authors.initials: YH
authors.lastname: Kim
authors.forename: Bong Joon
authors.initials: BJ
authors.lastname: Lee
authors.forename: Gook Hwa
authors.initials: GH
authors.lastname: Kim
authors.forename: Ik-Hyun
authors.initials: IH
authors.lastname: Kim
authors.forename: Myung-Ae
authors.initials: MA
authors.lastname: Chung
authors.forename: Sang-Don
authors.initials: SD
authors.lastname: Jung
mesh_terms: D002448:Cell Adhesion; D009474:Neurons / Q000166:cytology*; D055668:Photochemical Processes; D011094:Polyethyleneimine / Q000737:chemistry*; D017971:Tin Compounds / Q000737:chemistry; D014466:Ultraviolet Rays
chemical_list: D017971:Tin Compounds; C109984:indium tin oxide; D011094:Polyethyleneimine