title: Management of two cases of desquamative gingivitis with clobetasol and Calendula officinalis gel.
abstract: BACKGROUND
  The purpose of this paper is to describe two cases of desquamative gingivitis (DG) that were treated with a topic gel containing clobetasol propionate and Calendula officinalis L in an acetate tray over two years.
  
  
  METHODS
  Two patients with a diagnosis of lichen planus presenting as DG who had undergone previous treatments for this condition with no significant results, were treated by a handling gel containing clobetasol, nystatin, Calendula officinalis L and pectin in custom trays.
  
  
  RESULTS
  Both patients had remission of symptoms while using the trays and after they stopped the treatment, the symptomatic outbreaks were delayed and presented as less severe symptoms in the two years follow-up. The treatment is aimed primarily at reducing the length and severity of symptomatic outbreaks desquamative gingivitis.
  
  
  CONCLUSIONS
  This handling gel using a tray may be an efficacious treatment of desquamative gingivitis.
authors.affiliation: Department of Stomatology, Faculty of Dentistry, Universidade Federal do Parana, Curitiba, Parana, Brasil. man.machado@ufpr.br
authors.forename: Maria Angela Naval
authors.initials: MA
authors.lastname: Machado
authors.forename: Cintia Mussi Milani
authors.initials: CM
authors.lastname: Contar
authors.forename: Jean Ayres
authors.initials: JA
authors.lastname: Brustolim
authors.forename: Lisiane
authors.initials: L
authors.lastname: Candido
authors.forename: Luciana Reis
authors.initials: LR
authors.lastname: Azevedo-Alanis
authors.forename: Ana Maria Trindade
authors.initials: AM
authors.lastname: Gregio
authors.forename: Paula Cristina
authors.initials: PC
authors.lastname: Trevilatto
authors.forename: Antonio Adilson
authors.initials: AA
authors.lastname: Soares de Lima
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D020838:Calendula; D002990:Clobetasol / Q000008:administration & dosage*; D016503:Drug Delivery Systems; D005260:Female; D005782:Gels; D005891:Gingivitis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D017676:Lichen Planus, Oral / Q000150:complications; D008297:Male; D008517:Phytotherapy / Q000379:methods; D012074:Remission Induction / Q000379:methods
chemical_list: D000893:Anti-Inflammatory Agents; D005782:Gels; D002990:Clobetasol