title: Use it and lose it: lipofuscin accumulation in the midbrain of a coral reef fish.
abstract: Lipofuscin, an autofluorescent biomarker of physiological wear-and-tear, was concentrated in those areas of a fish's midbrain responsible for visual performance, suggesting a potentially strong link between physiological specialization, ecological adaptation and senescence.
authors.affiliation: Centre for Evolutionary Biology, School of Animal Biology & Centre for Microscopy, Characterisation and Analysis, University of Western Australia, Crawley, WA 6009, Australia. monica.gagliano@uwa.edu.au
authors.forename: M
authors.initials: M
authors.lastname: Gagliano
authors.forename: A K
authors.initials: AK
authors.lastname: Lema
authors.forename: M
authors.initials: M
authors.lastname: Depczynski
authors.forename: S
authors.initials: S
authors.lastname: Whalan
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D057894:Coral Reefs; D005399:Fishes / Q000502:physiology*; D008062:Lipofuscin / Q000032:analysis* / Q000502:physiology; D008636:Mesencephalon / Q000502:physiology*
chemical_list: D008062:Lipofuscin