title: Ocular neoplastic disease.
abstract: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss and often are asymptomatic. Clinical ophthalmologic examination may demonstrate leukocoria, abnormal pupillary light reflex, or a mass lesion with or without retinal detachment or hemorrhage. Retinoblastoma in children and uveal melanoma and ocular metastases in adults are the most important ocular malignant neoplasms referred for imaging to aid with diagnosis and staging. Familiarity with their common imaging appearances, the common patterns of spread, and the diagnostic findings of greatest concern to the ocular oncologist will enhance accuracy of imaging interpretation. Clinical ophthalmologic examination and imaging using B-scan ultrasound, A-scan ultrasound, fluorescein angiography, computed tomography and magnetic resonance imaging have complementary roles in ocular tumor staging and treatment assessment.
authors.affiliation: Department of Diagnostic Radiology, Yale New Haven Hospital, New Haven, CT, USA.
authors.forename: Amit
authors.initials: A
authors.lastname: Mahajan
authors.forename: Alison
authors.initials: A
authors.lastname: Crum
authors.forename: Michele H
authors.initials: MH
authors.lastname: Johnson
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Materin
mesh_terms: D000328:Adult; D002648:Child; D003287:Contrast Media; D003937:Diagnosis, Differential; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology; D005134:Eye Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000556:secondary; D005451:Fluorescein Angiography / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008545:Melanoma / Q000000981:diagnostic imaging / Q000473:pathology; D009367:Neoplasm Staging; D011856:Radiographic Image Enhancement / Q000379:methods; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography; D014604:Uveal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D000098943:Uveal Melanoma
chemical_list: D003287:Contrast Media