title: [Determination of trace BrO3- and Br- in Chinese patent drugs, waters and beverages by ion chromatography coupled with inductively coupled plasma mass spectrometry].
abstract: In the present study, a method for determination of BrO3- and Br- using ion chromatograghy coupling with inductively coupled plasma mass spectrometry (IC-ICP-MS) was developed. BrO3- and Br- were separated on a Hamilton PRP X-100 (150 x 4.1 mm, 10 microm) column guarding with a On-guard II RP (4 x 50 mm) column with 10 mmol x L(-1) NH4NO3 eluent solution at 2 mL x min(-1). By using 200 microL sample loop, the detection limits for BrO3- and Br were 0.35 and 0.36 microg x L(-1), respectively. BrO3- had good linearity in the range 4.8-160.0 ng x L(-1). The standard solution linear equation was y = 250.31x-45.43, and R2 = 0.9999. Br had good linearity in the range 4.2-140.0 ng x L(-1). The standard solution linear equation was y = 186.84x-127.10, and R2 = 0.9994. Recoveries of spiked samples were 98.9%-109.5% and 97.4%-106.1%, respectively. The samples included various kinds of Chinese patent drugs, waters, and beverages. Among them, 14 bottled drinking waters and 2 kinds of tap waters were found containing BrO-, while other samples were under BrO3- detection limit. Br- was detected in all samples.
authors.affiliation: School of Public Health, Peking University, Beijing 100191, China. lijichao728@163.com
authors.forename: Ji-chao
authors.initials: JC
authors.lastname: Li
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Ouyang
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Lai-lai
authors.initials: LL
authors.lastname: Yan
authors.forename: Shun-zong
authors.initials: SZ
authors.lastname: Chen
authors.forename: Yan-wen
authors.initials: YW
authors.lastname: Wu
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Wang
mesh_terms: D001628:Beverages / Q000032:analysis*; D017605:Bromine Compounds / Q000032:analysis*; D002845:Chromatography; D060766:Drinking Water / Q000032:analysis*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D057230:Limit of Detection; D013058:Mass Spectrometry
chemical_list: D017605:Bromine Compounds; D060766:Drinking Water; D004365:Drugs, Chinese Herbal