title: [Echocardiographic tissue Doppler imaging analysis of the systolic and early diastolic velocities of the mitral annulus motion in hypertrophic cardiomyopathy and in top-level athletes].
abstract: OBJECTIVE
  Echocardiographic Tissue Doppler Imaging (TDI) has been proposed for the differentiation of pathological left ventricular hypertrophy (e. g. hypertrophic cardiomyopathy, HCM) and physiologic left ventricular hypertrophy (athlete's heart). The aim of this study was the TDI analysis of the systolic (S') and early diastolic (E') velocities in patients (pts.) with non-obstructive hypertrophic cardiomyopathy (HCM) and in top-level athletes in consideration of the previously published cut-off values (S' < 9 cm/s, E' < 9 cm/s).
  
  
  METHODS
  Pulsed-wave TDI of the systolic and early-diastolic velocities was performed at the lateral and septal mitral annulus in the four-chamber view in 17 HCM pts (12 men; mean age 44 ± 16 years) and 80 consecutive athletes (80 men; mean age 26 ± 5 years).
  
  
  RESULTS
  Pts with HCM showed significantly decreased systolic velocities of the septal (S' septal: 5.1 ± 1.2 cm/s versus 9.5 ± 1.5 cm/s, p < 0.001) and lateral mitral annulus (S' lateral: 6.4 ± 2.0 cm/s vs. 10.5 ± 2.1 cm/s, p < 0.001). The early diastolic velocity of the mitral annulus E' was significantly decreased in HCM, too (E' septal: 5.9 ± 2.2 cm/s vs. 13.1 ± 2.9 cm/s, p < 0.001; E' lateral: 8.2 ± 3.0 cm/s vs. 16.5 ± 3.4 cm/s, p < 0.001).
  
  
  CONCLUSIONS
  Tissue Doppler Imaging of the systolic and early diastolic velocity of the mitral annulus might be helpful as a promising additional method for the echocardiographic differentiation between pathological and physiologic left ventricular hypertrophy.
authors.affiliation: Medizinische Klinik II (Kardiologie und Angiologie), Marienhospital Herne, Klinikum der Ruhr-Universität Bochum, Herne. Thomas.Butz@Marienhospital-Herne.de
authors.forename: T
authors.initials: T
authors.lastname: Butz
authors.forename: F
authors.initials: F
authors.lastname: van Buuren
authors.forename: K-P
authors.initials: KP
authors.lastname: Mellwig
authors.forename: C
authors.initials: C
authors.lastname: Langer
authors.forename: O
authors.initials: O
authors.lastname: Oldenburg
authors.forename: K A
authors.initials: KA
authors.lastname: Treusch
authors.forename: A
authors.initials: A
authors.lastname: Meissner
authors.forename: G
authors.initials: G
authors.lastname: Plehn
authors.forename: H-J
authors.initials: HJ
authors.lastname: Trappe
authors.forename: D
authors.initials: D
authors.lastname: Horstkotte
authors.forename: L
authors.initials: L
authors.lastname: Faber
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D059267:Cardiomegaly, Exercise-Induced / Q000502:physiology*; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D013177:Sports / Q000502:physiology*; D013599:Systole / Q000502:physiology; D055815:Young Adult