title: Pediatric molluscum contagiosum: reflections on the last challenging poxvirus infection, Part 2.
abstract: Molluscum contagiosum (MC) is a common dermatologic infection that usually affects school-aged children, sexually active young adults, and immunocompromised individuals. It is a benign and self-limiting disease, with most cases undergoing spontaneous resolution within 6 to 9 months. However, a more severe and prolonged course is associated with immunosuppression or atopic dermatitis. Treatment is recommended because of the high rate of associated symptoms, risk for transmissibility, and cosmetic or social concerns. Therapeutic modalities are subdivided into 3 types: destructive, immunomodulatory, and antiviral. We review the advantages and disadvantages of various agents and discuss combination therapy.
authors.affiliation: New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103-2714, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Lee
authors.forename: Robert A
authors.initials: RA
authors.lastname: Schwartz
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D016867:Immunocompromised Host; D007155:Immunologic Factors / Q000627:therapeutic use; D008976:Molluscum Contagiosum / Q000473:pathology / Q000628:therapy* / Q000821:virology; D008977:Molluscum contagiosum virus / Q000302:isolation & purification*; D012720:Severity of Illness Index; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D007155:Immunologic Factors