title: Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.
abstract: The pleckstrin homology domain of the FAPP1 protein (FAPP1-PH) recognizes phosphatidylinositol 4-phosphate [PtdIns(4)P] and is recruited to the Golgi apparatus in order to mediate trafficking to the cell surface. We report the complete (1)H, (13)C and (15)N resonance assignments of the FAPP1-PH in its free state and those induced by PtdIns(4)P or detergent micelles.
authors.affiliation: Henry Wellcome Building for Biomolecular NMR Spectroscopy, School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
authors.forename: Marc
authors.initials: M
authors.lastname: Lenoir
authors.forename: Sara B-M
authors.initials: SB
authors.lastname: Whittaker
authors.forename: Michael
authors.initials: M
authors.lastname: Overduin
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry* / Q000378:metabolism; D002793:Cholic Acids / Q000737:chemistry; D006056:Golgi Apparatus / Q000737:chemistry; D006801:Humans; D007554:Isotopes / Q000737:chemistry; D008823:Micelles; D019906:Nuclear Magnetic Resonance, Biomolecular; D018129:Phosphatidylinositol Phosphates / Q000737:chemistry / Q000378:metabolism; D010767:Phosphorylcholine / Q000031:analogs & derivatives / Q000737:chemistry; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D002793:Cholic Acids; D007554:Isotopes; D008823:Micelles; C487037:PLEKHA3 protein, human; D018129:Phosphatidylinositol Phosphates; D011994:Recombinant Proteins; C037178:phosphatidylinositol 4-phosphate; D010767:Phosphorylcholine; C028810:dodecylphosphocholine; C028213:3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate