title: Successful pregnancy with preimplantation genetic diagnosis in a woman with mosaic Turner syndrome.
abstract: OBJECTIVE
  To determine the efficacy of the preimplantation cytogenetic analysis of the embryos obtained from patient with mosaic Turner syndrome before an IVF program.
  
  
  METHODS
  Prospective cytogenetic analysis.
  
  
  METHODS
  University-based tertiary medical center.
  
  
  METHODS
  A 29 year-old female, a partner in a couple with male factor infertility, was diagnosed with mosaic Turner syndrome with a 45,X [17]/46,XX [13] karyotype.
  
  
  METHODS
  Preimplantation genetic diagnosis was performed on four blastomeres obtained from four different embryos by fluorescence in situ hybridization probes specific to chromosomes X, Y, 13, 18, 21 in an intracytoplasmic sperm injection cycle.
  
  
  METHODS
  Blastomeres with normal signals.
  
  
  RESULTS
  Two blastomeres detected as normal were transferred and pregnancy was achieved.
  
  
  CONCLUSIONS
  Preimplantation Genetic Diagnose should be considered in the infertility treatment of the patient with mosaic Turner Syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Assisted Reproduction Unit, Ankara, Turkey. gogsenonalan@yahoo.com
authors.forename: Gogsen
authors.initials: G
authors.lastname: Onalan
authors.forename: Zerrin
authors.initials: Z
authors.lastname: Yilmaz
authors.forename: Tulay
authors.initials: T
authors.lastname: Durak
authors.forename: Feride Iffet
authors.initials: FI
authors.lastname: Sahin
authors.forename: Hulusi Bulent
authors.initials: HB
authors.lastname: Zeyneloglu
mesh_terms: D000328:Adult; D020732:Cytogenetic Analysis; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000150:complications / Q000628:therapy*; D008297:Male; D009030:Mosaicism; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000379:methods; D016896:Treatment Outcome; D014424:Turner Syndrome / Q000150:complications / Q000235:genetics / Q000517:prevention & control / Q000628:therapy*