title: Association of physical activity and prognostic parameters in elderly patients with heart failure.
abstract: OBJECTIVE
  Assessment of habitual physical activity (PA) in patients with heart failure.
  
  
  METHODS
  This study included 50 patients with heart failure (61.9 ± 4.0 yr). Seven days of PA were assessed by questionnaire (AQ), pedometer, and accelerometer and correlated with prognostic markers including VO(2peak), percent left-ventricular ejection fraction, N-terminal pro-B-type natriuretic peptide, and New York Heart Association (NYHA) functional class.
  
  
  RESULTS
  Accelerometry showed a stronger correlation with VO(2peak) and NYHA class (R = .73 and R = -.68; p < .001) than AQ (R = .58 and R = -.65; p < .001) or pedometer (R = .52 and R = -.50; p < .001). In the multivariable regression model accelerometry was the only consistent independent predictor of VO(2peak) (p = .002). Moreover, when its accuracy of prediction was tested, 59% of NYHA I and 95% of NYHA III patients were correctly classified into their assigned NYHA classes based on their accelerometer activity.
  
  
  CONCLUSIONS
  PA assessed by accelerometer is significantly associated with exercise capacity in patients with heart failure and is predictive of disease severity. The data suggests that PA monitoring can aid in evaluating clinical status.
authors.affiliation: Institute of Exercise and Health Sciences, University of Basel, Basel, Switzerland.
authors.forename: Melissa
authors.initials: M
authors.lastname: Jehn
authors.forename: Arno
authors.initials: A
authors.lastname: Schmidt-Trucksäss
authors.forename: Henner
authors.initials: H
authors.lastname: Hanssen
authors.forename: Tibor
authors.initials: T
authors.lastname: Schuster
authors.forename: Martin
authors.initials: M
authors.lastname: Halle
authors.forename: Friedrich
authors.initials: F
authors.lastname: Koehler
mesh_terms: D000368:Aged; D015415:Biomarkers; D016002:Discriminant Analysis; D016552:Ergometry / Q000295:instrumentation*; D015444:Exercise; D017079:Exercise Tolerance; D005260:Female; D006333:Heart Failure / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D015415:Biomarkers