title: Current effective topical therapies in the management of psoriasis.
abstract: Topical therapy forms the cornerstone of treatment in the management of psoriasis. It plays a significant role as monotherapy in mild to moderate psoriasis, and it is used predominantly as adjunctive therapy in moderate to severe forms of the disease. Over the past decade, the topical treatment of psoriasis has evolved from the age-old applications, such as coal tar, to the more cosmetically acceptable and efficacious options containing topical corticosteroids, vitamin D analogues, and combined agents. With the advent of topical therapies in tailored vehicles and sophisticated delivery modes, the outlook for effectively managing psoriasis with topical approaches appears promising. To ensure therapeutic success, patient education about the disease, treatment options, proper administration, and adverse effects is essential, which will alleviate the common problem of poor patient adherence and promote more optimal clinical outcomes.
authors.affiliation: Department of Medicine, McMaster University, Hamilton, ON, Canada 2.
authors.forename: A
authors.initials: A
authors.lastname: Kurian
authors.forename: B
authors.initials: B
authors.lastname: Barankin
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology; D012176:Retinoids / Q000008:administration & dosage*
chemical_list: D000305:Adrenal Cortex Hormones; D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; D012176:Retinoids