title: Transporting live donor kidneys for kidney paired donation: initial national results.
abstract: Optimizing the possibilities for kidney-paired donation (KPD) requires the participation of donor-recipient pairs from wide geographic regions. Initially it was envisaged that donors would travel to the recipient center; however, to minimize barriers to participation and simplify logistics, recent trends have involved transporting the kidneys rather than the donors. The goal of this study was to review outcomes of this practice. KPD programs throughout the United States were directly queried about all transplants involving live donor kidney transport. Early graft function was assessed by urine output in the first 8 h, postoperative serum creatinine trend, and incidence of delayed graft function. Between April 27, 2007 and April 29, 2010, 56 live donor kidneys were transported among 30 transplant centers. Median CIT was 7.2 h (IQR 5.5-9.7, range 2.5-14.5). Early urine output was robust (>100 cc/h) in all but four patients. Creatinine nadir was <2.0 mg/dL in all (including the four with lower urine output) but one patient, occurring at a median of 3 days (IQR 2-5, range 1-49). No patients experienced delayed graft function as defined by the need for dialysis in the first week. Current evidence suggests that live donor kidney transport is safe and feasible.
authors.affiliation: Department of Surgery Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA. dorry@jhmi.edu
authors.forename: D L
authors.initials: DL
authors.lastname: Segev
authors.forename: J L
authors.initials: JL
authors.lastname: Veale
authors.forename: J C
authors.initials: JC
authors.lastname: Berger
authors.forename: J M
authors.initials: JM
authors.lastname: Hiller
authors.forename: R L
authors.initials: RL
authors.lastname: Hanto
authors.forename: D B
authors.initials: DB
authors.lastname: Leeser
authors.forename: S R
authors.initials: SR
authors.lastname: Geffner
authors.forename: S
authors.initials: S
authors.lastname: Shenoy
authors.forename: W I
authors.initials: WI
authors.lastname: Bry
authors.forename: S
authors.initials: S
authors.lastname: Katznelson
authors.forename: M L
authors.initials: ML
authors.lastname: Melcher
authors.forename: M A
authors.initials: MA
authors.lastname: Rees
authors.forename: E N S
authors.initials: EN
authors.lastname: Samara
authors.forename: A K
authors.initials: AK
authors.lastname: Israni
authors.forename: M
authors.initials: M
authors.lastname: Cooper
authors.forename: R J
authors.initials: RJ
authors.lastname: Montgomery
authors.forename: L
authors.initials: L
authors.lastname: Malinzak
authors.forename: J
authors.initials: J
authors.lastname: Whiting
authors.forename: D
authors.initials: D
authors.lastname: Baran
authors.forename: J I
authors.initials: JI
authors.lastname: Tchervenkov
authors.forename: J P
authors.initials: JP
authors.lastname: Roberts
authors.forename: J
authors.initials: J
authors.lastname: Rogers
authors.forename: D A
authors.initials: DA
authors.lastname: Axelrod
authors.forename: C E
authors.initials: CE
authors.lastname: Simpkins
authors.forename: R A
authors.initials: RA
authors.lastname: Montgomery
mesh_terms: D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D051799:Delayed Graft Function / Q000209:etiology; D033001:Directed Tissue Donation; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods* / Q000502:physiology; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation; D013997:Time Factors; D009927:Tissue and Organ Procurement; D014186:Transportation; D014481:United States
chemical_list: D003404:Creatinine