title: Acute poison exposure in the emergency department: a 2-year study in a university hospital.
abstract: BACKGROUND
  Pattern of acute poison exposure varies in the different areas. The information will be useful for prevention.
  
  
  OBJECTIVE
  To evaluate pattern, severity and clinical outcome of acute poison exposure in the Emergency Department of a University Hospital in Thailand.
  
  
  METHODS
  Medical records of all acute poison exposure cases, presented the Emergency Department of Thammasat University Hospital between October 1, 2006 and September 30, 2008 were reviewed retrospectively. Demographic characteristics, exposure time, agents, route and cause of exposure, clinical course and outcome were analyzed.
  
  
  RESULTS
  Of the total 76,805 Emergency Department visits, 1112 cases were related to acute poison exposures, which were accounted for 1.4%. Sixty-five percents were female. Patients whom their ages ranging from 21 to 40 years old showed the highest rate of acute poison exposures. Intentional and unintentional exposures accounted for 52.7% and 44.9%, respectively. Intentional exposure was the major cause of exposure in the age group of 11-40 years, while unintentional exposure was the major cause of exposure in children. Pharmaceutical products (38.1%) were the most common category of substances involved in acute poison exposure followed by bites and stings (31.7%) and household products (17.6%). The substances most frequently involved were acetaminophen (17.7%) and toilet cleaning agents (12.3%). Fifty-six (5%) cases developed severe clinical course and three (0.27%) patients died. Pesticide and toilet cleaning agents were responsible for all these fatalities.
  
  
  CONCLUSIONS
  Acetaminophen and toilet cleaning agents were commonly involved in acute poison exposure. Pesticide and toilet cleaning agents caused severe morbidity and mortality. Unintentional exposure was the major cause of exposure in children. Public education regarding the danger of these agents and prevention of the poison exposure in children should be emphasized.
authors.affiliation: Department of Emergency Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand. chitladal1@gmail.com
authors.forename: Chitlada
authors.initials: C
authors.lastname: Limjindaporn
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data; D006795:Household Products / Q000506:poisoning*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010575:Pesticides / Q000506:poisoning; D011041:Poisoning / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D013785:Thailand / Q000453:epidemiology
chemical_list: D010575:Pesticides; D000082:Acetaminophen