title: Determination of nitroanilines in hair dye using polymer monolith microextraction coupled with HPLC.
abstract: In this study, a novel method for the determination of nitroanilines in hair dye samples has been developed based on poly(methacrylic acid-co-ethylene glycol dimethacrylate) monolith microextraction (PMME) and high-performance liquid chromatography (HPLC) analysis. Four nitroanilines, p-nitroaniline (PNAL), m-nitroaniline (MNAL), o-nitroaniline (ONAL), and 2,4-dinitroaniline (DNAL), are studied as representatives. To obtain optimum extraction efficiency, several experimental parameters including sample flow rate, sample volume, sample pH, and eluent flow rate have been investigated. Under the optimal experimental conditions, the linear regression coefficients of the standard curves are greater than 0.9990. The limits of detection for p-nitroaniline, m-nitroaniline, o-nitroaniline, and 2,4-dinitroaniline are 0.012, 0.008, 0.018, and 0.005 μg/mL, respectively. The intraday and interday relative standard deviations are less than 3.1 and 5.4%, respectively. The proposed method is simple, rapid, sensitive, and competent when used for the determination of nitroanilines in hair dye samples and the accuracy is assessed through recovery experiments.
authors.affiliation: College of Chemistry, Jilin University, Changchun, P. R. China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Xiao
authors.forename: Changli
authors.initials: C
authors.lastname: Bao
authors.forename: Qiong
authors.initials: Q
authors.lastname: Jia
authors.forename: Riyan
authors.initials: R
authors.lastname: Su
authors.forename: Weihong
authors.initials: W
authors.lastname: Zhou
authors.forename: Jianbo
authors.initials: J
authors.lastname: Jia
mesh_terms: D000327:Adsorption; D000814:Aniline Compounds / Q000032:analysis* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006202:Hair Dyes / Q000032:analysis*; D011108:Polymers / Q000737:chemistry; D052617:Solid Phase Microextraction / Q000295:instrumentation / Q000379:methods*
chemical_list: D000814:Aniline Compounds; D006202:Hair Dyes; D011108:Polymers; C008625:nitroaniline