title: Nonlinear effects of noradrenergic modulation of olfactory bulb function in adult rodents.
abstract: The mammalian main olfactory bulb receives a significant noradrenergic input from the locus coeruleus. Norepinephrine (NE) is involved in acquisition of conditioned odor preferences in neonatal animals, in some species-specific odor-dependent behaviors, and in adult odor perception. We provide a detailed review of the functional role of NE in adult rodent main olfactory bulb function. We include cellular, synaptic, network, and behavioral data and use computational simulations to tie these different types of data together.
authors.affiliation: Department of Neurobiology and Behavior, W245 Mudd Hall, Cornell University, Ithaca, NY 14853, USA. cl243@cornell.edu
authors.forename: Christiane
authors.initials: C
authors.lastname: Linster
authors.forename: Qiang
authors.initials: Q
authors.lastname: Nai
authors.forename: Matthew
authors.initials: M
authors.lastname: Ennis
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D008125:Locus Coeruleus / Q000502:physiology*; D023421:Models, Animal; D009638:Norepinephrine / Q000502:physiology*; D009812:Odorants; D009830:Olfactory Bulb / Q000502:physiology*; D051381:Rats; D013045:Species Specificity
chemical_list: D009638:Norepinephrine