title: Individual assessment of inherent arterial stiffness using nomogram and pulse wave velocity index: the Ohasama study.
abstract: We measured the brachial-ankle pulse wave velocity (baPWV) in 491 normotensives and determined the "PWV index" (measured baPWV-theoretical baPWV) in 491 normotensives and 83 controlled hypertensives. Linear regression analysis revealed that the theoretical baPWV (cm/sec) was 0.21 × age(2) (years(2))-13.73 × age (years) + 0.05 × mean arterial pressure(2) (mmHg(2)) + 3.95 × heart rate (bpm) + 36.49 × gender (1 male; 0 female) + 733 (R(2) = 0.53). The calculated PWV index was significantly higher in 13 smokers than 70 nonsmokers among controlled hypertensives. The calculated PWV index might provide more precise information about inherent arterial stiffness.
authors.affiliation: Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, Sendai, Japan. rieko@idac.tohoku.ac.jp
authors.forename: Rieko
authors.initials: R
authors.lastname: Hatanaka
authors.forename: Taku
authors.initials: T
authors.lastname: Obara
authors.forename: Daisuke
authors.initials: D
authors.lastname: Watabe
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kimura
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Hanazawa
authors.forename: Hiromi
authors.initials: H
authors.lastname: Ohba
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Aikawa
authors.forename: Azusa
authors.initials: A
authors.lastname: Hara
authors.forename: Hirohito
authors.initials: H
authors.lastname: Metoki
authors.forename: Kei
authors.initials: K
authors.lastname: Asayama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuya
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Ohkubo
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Totsune
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imai
mesh_terms: D000328:Adult; D000368:Aged; D055109:Ankle Brachial Index / Q000379:methods*; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001916:Brachial Artery / Q000503:physiopathology*; D016022:Case-Control Studies; D004548:Elasticity / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007564:Japan; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D049451:Nomograms; D011673:Pulsatile Flow / Q000502:physiology*; D012907:Smoking / Q000503:physiopathology