title: [Lacosamide: a new generation in the treatment of epilepsy].
abstract: Despite the large number of antiepileptic drugs (AED) available today, more than 30% of patients with epilepsy do not manage to achieve adequate control over their seizures. For patients, the administration of the latest AED can be a good alternative, prior to surgery or when there are contraindications against it. Third generation AED offer different mechanisms of action and tolerability profiles that are more favourable than those of the first and second generations. Lacosamide has recently been approved by the European Medicines Agency (EMEA) and its United States counterpart (FDA) as an adjuctive AED in partial onset seizures in adults over the age of 16, thus making it a novel option in the treatment of epilepsy.
authors.affiliation: Hospital Ruber Internacional, 28034 Madrid, Espana. agnagel@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Gil-Nagel
authors.forename: H
authors.initials: H
authors.lastname: Marin
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D000078334:Lacosamide; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D000081:Acetamides; D000927:Anticonvulsants; D000078334:Lacosamide