title: Accidental and iatrogenic causes of acute kidney injury.
abstract: OBJECTIVE
  Ingestions and iatrogenic administration of drugs are all too common causes of acute kidney injury. This review will discuss these preventable causes of acute kidney injury.
  
  
  RESULTS
  Recent studies have examined the pathophysiology of acute kidney injury by several commonly used drugs. These studies have shown that drugs and toxins can cause acute kidney injury by altering renal hemodynamics, direct tubular injury or causing renal tubular obstruction.
  
  
  CONCLUSIONS
  Knowledge of the drugs that cause acute kidney injury and how this injury is manifested can lead to improved diagnosis and treatment with the ultimate goal of prevention.
authors.affiliation: Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9063, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Twombley
authors.forename: Michel
authors.initials: M
authors.lastname: Baum
authors.forename: Jyothsna
authors.initials: J
authors.lastname: Gattineni
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000617:Aminoglycosides / Q000009:adverse effects; D057911:Angiotensin Receptor Antagonists / Q000009:adverse effects; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D002648:Child; D003287:Contrast Media / Q000009:adverse effects; D006801:Humans; D007049:Iatrogenic Disease; D014640:Vancomycin / Q000009:adverse effects
chemical_list: D000617:Aminoglycosides; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003287:Contrast Media; D014640:Vancomycin