title: Novel domino oxidative coupling: C-C bond formation sequence to highly functionalized dibenzo[a,c]cycloheptenes.
abstract: A domino sequence involving various MoCl(5)-mediated oxidations followed by trapping and supposed [3,3]-sigmatropic rearrangement provides a fast access to the full carbon skeleton of metasequirin-B. A variety of different moieties R(1) and R(2) are tolerated.
authors.affiliation: Kekulé Institute for Organic Chemistry and Biochemistry, Bonn University, Bonn, Germany.
authors.forename: Kristina
authors.initials: K
authors.lastname: Hackeloer
authors.forename: Gregor
authors.initials: G
authors.lastname: Schnakenburg
authors.forename: Siegfried R
authors.initials: SR
authors.lastname: Waldvogel
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry; D003500:Cyclization; D003986:Dibenzocycloheptenes / Q000138:chemical synthesis* / Q000737:chemistry; D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry; D010084:Oxidation-Reduction; D058451:Oxidative Coupling
chemical_list: D001555:Benzene Derivatives; D002712:Chlorides; D003986:Dibenzocycloheptenes; D017705:Lignans; C557765:metasequirin B; D008982:Molybdenum; C085192:molybdenum chloride