title: Histological analysis of low-intensity laser therapy effects in peripheral nerve regeneration in Wistar rats.
abstract: OBJECTIVE
  Analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration of rats submitted to controlled crush through histological analysis.
  
  
  METHODS
  Were used 20 Wistar rats, to analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration, where the injury of the type axonotmesis was induced by a haemostatic clamp Crile (2nd level of the rack). The animals were randomly distributed in 2 groups. Control group (CG n = 10) and Laser group (LG n = 10). These were subdivided in 2 subgroups each, according to the euthanasia period: (CG14 - n = 5 and CG21 - n = 5) and (LG14 - n = 5 and LG21 - n = 5). At the end of treatment, the samples were removed and prepared for histological analysis, where were analyzed and quantified the following findings: Schwann cells, myelinic axons with large diameter and neurons.
  
  
  RESULTS
  In the groups submitted to low-intensity laser therapy, were observed an increase in the number of all analyzed aspects with significance level.
  
  
  CONCLUSIONS
  The irradiation with low intensity laser (904nm) influenced positively the regeneration of the sciatic nerve in Wistar rats after being injured by crush (axonotmesis), becoming the nerve recovery more rapid and efficient.
authors.affiliation: Department of Physiotherapy, UNAMA, Belem, PA, Brazil. camaracibele@yahoo.com.br
authors.forename: Cibele Nazaré da Silva
authors.initials: CN
authors.lastname: Câmara
authors.forename: Marcus Vinicius Henriques
authors.initials: MV
authors.lastname: Brito
authors.forename: Edvaldo Lima
authors.initials: EL
authors.lastname: Silveira
authors.forename: Diego Sá Guimarães da
authors.initials: DS
authors.lastname: Silva
authors.forename: Vivian Roberta Ferreira
authors.initials: VR
authors.lastname: Simões
authors.forename: Roberto Waldesmand Farias
authors.initials: RW
authors.lastname: Pontes
mesh_terms: D000818:Animals; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D009409:Nerve Crush; D009416:Nerve Regeneration / Q000502:physiology / Q000528:radiation effects*; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000502:physiology / Q000528:radiation effects; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000166:cytology / Q000293:injuries / Q000502:physiology*