title: Neonatal sludge: a finding of congenital hypothyroidism.
abstract: Congenital hypothyroidism is one of the most urgent diseases of the neonate. When diagnosed and treated at an early stage, its most important complication, mental retardation, is preventable. The signs of congenital hypothyroidism are nonspecific in neonates. Only 5% of the cases have characteristic clinical findings. One of the most important and earliest signs is prolonged jaundice during the neonatal period. We report herein a case of congenital hypothyroidism, who presented with icterus accompanied with sludge formation into the gallbladder, which disappeared after treatment with L-thyroxine.
authors.affiliation: Erciyes University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, 38039 Kayseri, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Kurtoğlu
authors.forename: Dilek
authors.initials: D
authors.lastname: Coban
authors.forename: Mustafa Ali
authors.initials: MA
authors.lastname: Akın
authors.forename: Leyla
authors.initials: L
authors.lastname: Akın
authors.forename: Ali
authors.initials: A
authors.lastname: Yıkılmaz
mesh_terms: D003409:Congenital Hypothyroidism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D008297:Male; D013974:Thyroxine / Q000627:therapeutic use; D014463:Ultrasonography
chemical_list: D013974:Thyroxine