title: The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction.
abstract: The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.
authors.affiliation: Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30302-4098, USA.
authors.forename: Chaofeng
authors.initials: C
authors.lastname: Dai
authors.forename: Lifang
authors.initials: L
authors.lastname: Wang
authors.forename: Jia
authors.initials: J
authors.lastname: Sheng
authors.forename: Hanjing
authors.initials: H
authors.lastname: Peng
authors.forename: Alexander Boryanov
authors.initials: AB
authors.lastname: Draganov
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huang
authors.forename: Binghe
authors.initials: B
authors.lastname: Wang
mesh_terms: D001483:Base Sequence; D001897:Boronic Acids / Q000737:chemistry*; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry / Q000235:genetics
chemical_list: D001897:Boronic Acids; D009838:Oligodeoxyribonucleotides; D003300:Copper; D004247:DNA