title: Stereotactic radiotherapy of primary lung cancer and other targets: results of consultant meeting of the International Atomic Energy Agency.
abstract: To evaluate the current status of stereotactic body radiotherapy (SBRT) and identify both advantages and disadvantages of its use in developing countries, a meeting composed of consultants of the International Atomic Energy Agency was held in Vienna in November 2006. Owing to continuous developments in the field, the meeting was extended by subsequent discussions and correspondence (2007-2010), which led to the summary presented here. The advantages and disadvantages of SBRT expected to be encountered in developing countries were identified. The definitions, typical treatment courses, and clinical results were presented. Thereafter, minimal methodology/technology requirements for SBRT were evaluated. Finally, characteristics of SBRT for developing countries were recommended. Patients for SBRT should be carefully selected, because single high-dose radiotherapy may cause serious complications in some serial organs at risk. Clinical experiences have been reported in some populations of lung cancer, lung oligometastases, liver cancer, pancreas cancer, and kidney cancer. Despite the disadvantages expected to be experienced in developing countries, SBRT using fewer fractions may be useful in selected patients with various extracranial cancers with favorable outcome and low toxicity.
authors.affiliation: Hiroshima University Hospital, Department of Radiation Oncology, Hiroshima, Japan. nagat@hiroshima-u.ac.jp
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nagata
authors.forename: Joern
authors.initials: J
authors.lastname: Wulf
authors.forename: Ingmar
authors.initials: I
authors.lastname: Lax
authors.forename: Robert
authors.initials: R
authors.lastname: Timmerman
authors.forename: Frank
authors.initials: F
authors.lastname: Zimmermann
authors.forename: Igor
authors.initials: I
authors.lastname: Stojkovski
authors.forename: Branislav
authors.initials: B
authors.lastname: Jeremic
mesh_terms: D001317:Austria; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000601:surgery*; D003906:Developing Countries; D006801:Humans; D007390:International Agencies; D007680:Kidney Neoplasms / Q000532:radiotherapy; D008113:Liver Neoplasms / Q000601:surgery; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D009678:Nuclear Energy; D010190:Pancreatic Neoplasms / Q000532:radiotherapy; D010315:Particle Accelerators / Q000295:instrumentation / Q000592:standards; D011785:Quality Assurance, Health Care / Q000592:standards; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects / Q000193:education / Q000295:instrumentation / Q000592:standards*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods