title: Prospective blinded comparison of polyp size on computed tomography colonography and endoscopic colonoscopy.
abstract: OBJECTIVE
  The size of polyps found on computed tomography colonography (CTC) has been suggested as the major determinant of patient management. We compared polyp size as seen on CTC with endoscopic visualization, in vivo probe measurement, and ex vivo size before and after fixation.
  
  
  METHODS
  Polyps measured on CTC sent for endoscopic removal were evaluated for polyp size in a blinded fashion by endoscopic estimation, in vivo probe measurement, and after removal.
  
  
  RESULTS
  Fifty-six polyps were included in the study. There was no significant difference between CTC polyp size, real-time colonoscopy size estimation, or probe measurement. The size of polyp measured immediately ex vivo and after pathology fixation was significantly smaller. Management would be altered in 6 of 56 polyps (10.7%) on the basis of differences between size of the polyp on endoscopy and CTC.
  
  
  CONCLUSIONS
  (1) CTC polyp size measurement is not significantly different from colonoscopy in vivo visual estimation and linear probe measurement. (2) Differences in size of polyps as measured on CTC and endoscopy will affect patient management in 10% of cases.
authors.affiliation: Section of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin 53792, USA.
authors.forename: Courtney
authors.initials: C
authors.lastname: Barancin
authors.forename: Perry J
authors.initials: PJ
authors.lastname: Pickhardt
authors.forename: David H
authors.initials: DH
authors.lastname: Kim
authors.forename: Bret
authors.initials: B
authors.lastname: Spier
authors.forename: Mary
authors.initials: M
authors.lastname: Lindstrom
authors.forename: Mark
authors.initials: M
authors.lastname: Reichelderfer
authors.forename: Deepak
authors.initials: D
authors.lastname: Gopal
authors.forename: Patrick
authors.initials: P
authors.lastname: Pfau
mesh_terms: D003111:Colonic Polyps / Q000175:diagnosis* / Q000473:pathology*; D023881:Colonography, Computed Tomographic / Q000379:methods*; D003113:Colonoscopy / Q000379:methods*; D006801:Humans; D011446:Prospective Studies