title: [Bladder necrosis after an immediate post-operative mitomycin C instillation].
abstract: Administration of intravesical chemotherapy by mitomycin C decreases the risk of recurrence in non-muscle-invasive bladder tumours. We report the case of a man, who presented a full bladder necrosis after an immediate adjuvant mitomycin C instillation. The failure of resection of the necrotic area led us to perform a total cystectomy with an intestinal reconstruction. A review of the literature showed four other cases of necrosis of the bladder or of lower urinary tract. In all cases the rules of early instillation were observed.
authors.affiliation: Service d'Urologie, CHU Hôtel-Dieu, 44000 Nantes, France.
authors.forename: J
authors.initials: J
authors.lastname: Branchereau
authors.forename: F
authors.initials: F
authors.lastname: Luyckx
authors.forename: M
authors.initials: M
authors.lastname: Hitier
authors.forename: G
authors.initials: G
authors.lastname: Karam
authors.forename: O
authors.initials: O
authors.lastname: Bouchot
authors.forename: J
authors.initials: J
authors.lastname: Rigaud
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects*; D009336:Necrosis / Q000139:chemically induced; D011183:Postoperative Complications / Q000139:chemically induced* / Q000473:pathology*; D001743:Urinary Bladder / Q000473:pathology*
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin