title: Meningitis and septicemia caused by nontypeable Haemophilus influenzae in a previously healthy 2-year-old girl.
abstract: Nontypeable Haemophilus influenzae (NTHi) commonly colonizes the upper respiratory tract of children and causes otitis media, sinusitis, and bronchitis. Invasive NTHi diseases such as meningitis and septicemia have rarely been reported, especially in children with underlying predisposing conditions such as head trauma and immune compromise. However, we report a previously healthy 2-year-old girl who developed meningitis and septicemia caused by NTHi biotype ΙΙΙ. She was treated with dexamethasone, meropenem, and ceftriaxone, and recovered uneventfully. We wish to emphasize that NTHi should be borne in mind as a potential pathogen that can cause meningitis and septicemia, even in previously healthy children.
authors.affiliation: Department of Pediatrics, Shizuoka City Shimizu Hospital, Shizuoka, Japan. takaosurf@hotmail.com
authors.forename: Takao
authors.initials: T
authors.lastname: Ito
authors.forename: Hironori
authors.initials: H
authors.lastname: Shibata
authors.forename: Mie
authors.initials: M
authors.lastname: Nakazawa
authors.forename: Michiko
authors.initials: M
authors.lastname: Myokai
authors.forename: Kazuko
authors.initials: K
authors.lastname: Ikegaya
authors.forename: Ken
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Kamimaki
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000382:microbiology*; D002443:Ceftriaxone / Q000627:therapeutic use; D002675:Child, Preschool; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D007564:Japan; D008583:Meningitis, Haemophilus / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000382:microbiology*; D000077731:Meropenem; D013845:Thienamycins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D013845:Thienamycins; D002443:Ceftriaxone; D003907:Dexamethasone; D000077731:Meropenem