title: [Acute kidney injury].
abstract: New guidelines of the "Kidney Disease: Improving Global Outcome" (KDIGO) working group standardize the definition of acute kidney injury (AKI) and acute kidney disease (AKD) allowing the assessment of prognosis and efficacy of prophylactic and therapeutic measures in different patient cohorts. The degree of severity and the duration of acute kidney injury are critical factors for the development of chronic kidney disease and mortality. The achievement of optimal fluid volumes is a cornerstone in the treatment during the early phase of AKI, while volume overload should be avoided in the late phase of established AKI. Recently employed biomarkers are promising for the early detection and prognosis of AKI, but cannot yet be used as routine tests. Microscopic urinalysis, a very old and cost-effective diagnostic measure, provides valuable informations about the severity and the course of AKI.
authors.affiliation: Klinik für Nephrologie, Universitätsklinikum Essen, Universität Duisburg-Essen, 45122 Essen. thorsten.feldkamp@uk-essen.de
authors.forename: T
authors.initials: T
authors.lastname: Feldkamp
authors.forename: A
authors.initials: A
authors.lastname: Bienholz
authors.forename: A
authors.initials: A
authors.lastname: Kribben
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D003404:Creatinine / Q000097:blood; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control; D007677:Kidney Function Tests / Q000379:methods; D017410:Practice Guidelines as Topic; D011379:Prognosis; D015996:Survival Rate; D016896:Treatment Outcome; D016482:Urinalysis / Q000379:methods
chemical_list: D003404:Creatinine