title: A novel aporphine alkaloid from Magnolia officinalis.
abstract: A novel aporphine alkaloid, magnofficine (1), has been isolated from the root barks of the Chinese medicinal plant Magnolia officinalis, along with seven known compounds. Elucidations of their structures were achieved by spectroscopic methods. Magnofficine is the first example of an adduct of aporphine alkaloid and 4-hydroxyphenethylamino bridged by a methylene.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China.
authors.forename: Zuo-Fu
authors.initials: ZF
authors.lastname: Guo
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Wang
authors.forename: Jian-Guang
authors.initials: JG
authors.lastname: Luo
authors.forename: Jun
authors.initials: J
authors.lastname: Luo
authors.forename: Jun-Song
authors.initials: JS
authors.lastname: Wang
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
mesh_terms: D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification*; D031566:Magnolia / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry
chemical_list: D001060:Aporphines; C560477:magnofficine