title: Effects of I-131 therapy on gonads and pregnancy outcome in patients with thyroid cancer.
abstract: We examined the effects of I-131 therapy for thyroid cancer on female and male gonads and pregnancy outcome. After an extensive review of the published literature we concluded that ablative administration of I-131 therapy may result in transient abnormalities of ovarian and testicular function, but subsequent pregnancies are safe without any significant consequences to offspring outcome.
authors.affiliation: Department of Nuclear Medicine, University Hospital of Ioannina, Ioannina, Greece. csioka@yahoo.com
authors.forename: Chrissa
authors.initials: C
authors.lastname: Sioka
authors.forename: Andreas
authors.initials: A
authors.lastname: Fotopoulos
mesh_terms: D018265:Carcinoma, Papillary, Follicular / Q000532:radiotherapy*; D005260:Female; D006066:Gonads / Q000502:physiology / Q000528:radiation effects*; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D007774:Lactation / Q000502:physiology / Q000528:radiation effects; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000532:radiotherapy*; D011256:Pregnancy Outcome; D013964:Thyroid Neoplasms / Q000532:radiotherapy*
chemical_list: D007457:Iodine Radioisotopes