title: A new fluorescent chemosensor for fluoride anion based on a pyrrole-isoxazole derivative.
abstract: Molecules containing polarized NH fragments that behave as anion-binding motifs are widely used as receptors for recognition and sensing purposes in aprotic solvents. We present here a new example of a receptor, 3-amino-5-(4,5,6,7-tetrahydro-1H-indol-2-yl)isoxazole-4-carboxamide (receptor 1), which contains pyrrole, amide and amino subunits. This receptor shows both changes in its UV-vis absorption and fluorescence emission spectra upon the addition of F(-), resulting in highly selectivity for fluoride detection over other anions, such as Cl(-), Br(-), I(-), HSO(4) (-), H(2)PO(4) (-) and AcO(-) in CH(3)CN. (1)H NMR titration, time-dependent density functional theory (TDDFT) calculations and other experiments confirm that the sensing process is brought about by deprotonation of the pyrrole-NH in receptor 1.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
authors.forename: Zhipei
authors.initials: Z
authors.lastname: Yang
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.forename: Fangbin
authors.initials: F
authors.lastname: Gong
authors.forename: Shayu
authors.initials: S
authors.lastname: Li
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Jin Shi
authors.initials: JS
authors.lastname: Ma
authors.forename: Lyubov N
authors.initials: LN
authors.lastname: Sobenina
authors.forename: Albina I
authors.initials: AI
authors.lastname: Mikhaleva
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Yang
authors.forename: Boris A
authors.initials: BA
authors.lastname: Trofimov