title: Detection of extensive melorheostosis on bone scintigram performed for suspected metastases.
abstract: Melorheostosis is a rare but benign disorder characterized by asymmetric osteosclerotic dysplasia. Radiographic appearances are characteristic and described as "melting wax flowing down a candle." This disorder may involve more than one bone contiguously across the joints following a sclerotomal distribution. It is often asymptomatic but occasionally presents with pain and contractures. The authors report accidental detection of bilateral upper and lower limb melorheostosis in an elderly woman with the history of breast cancer and recent onset of low back pain, which was referred for a bone scintigram for suspected metastases. The images showed bilateral femoral and tibial melorheostosis, which was subsequently confirmed on plain radiograph and by clinical follow-up.
authors.affiliation: Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, England, United Kingdom. luke@sonoda.co.uk
authors.forename: Luke I
authors.initials: LI
authors.lastname: Sonoda
authors.forename: Mohamed Y
authors.initials: MY
authors.lastname: Halim
authors.forename: Kottekkattu K
authors.initials: KK
authors.lastname: Balan
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008557:Melorheostosis / Q000000981:diagnostic imaging*; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging