title: [Evaluation on clinical value of serum CA-125 level in hepatitis cirrhosis].
abstract: OBJECTIVE
  To determine the association between elevated levels of serum cancer antigen (CA) 125 and hepatitis cirrhosis in different stage, and also to explore the clinical application value of serum CA-125.
  
  
  METHODS
  During June to December in 2008, 200 cases with hepatitis cirrhosis were random selected in our hospital. CA-125 levels were measured by electrochemiluminescence immunization assay in sera collected from these cases which were termed with Child-Paugh classification and analyzed by SAS.
  
  
  RESULTS
  Serum CA-125 levels were correlated closely with ascites, primary peritonitis and liver function Child-Paugh classification, but no associated with primary carcinoma of liver and other liver function index,such as ALT, AST, ALB, TBIL and PT.
  
  
  CONCLUSIONS
  The levels of serum CA-125 in hepatitis cirrhosis patients were osculating correlating with lesion of liver and ascite degree, could serve as a sensitive and conventional laboratory index for liver lesion degree and monitoring ascite generation. It was necessary to further study on the association with serum CA-125 level with primary hepatic carcinoma.
authors.affiliation: Clinical Diagnosis Center, 302 Hospital of the PLA, Beijing 100039, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Jia
authors.initials: J
authors.lastname: Liu
authors.forename: Jing-xia
authors.initials: JX
authors.lastname: Guo
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Ma
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.forename: Ai-xia
authors.initials: AX
authors.lastname: Liu
authors.forename: Wei-ning
authors.initials: WN
authors.lastname: Xu
authors.forename: Bo-an
authors.initials: BA
authors.lastname: Li
authors.forename: Yuan-li
authors.initials: YL
authors.lastname: Mao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001201:Ascites / Q000473:pathology; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000097:blood* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D018394:CA-125 Antigen