title: Copper-catalyzed trifluoromethylation of aryl iodides with potassium (trifluoromethyl)trimethoxyborate.
abstract: Potassium (trifluoromethyl)trimethoxyborate is introduced as a new source of CF(3) nucleophiles in copper-catalyzed trifluoromethylation reactions. The crystalline salt is stable on storage, easy to handle, and can be obtained in near-quantitative yields simply by mixing B(OMe)(3), CF(3)SiMe(3), and KF. The trifluoromethylation reagent allows the conversion of various aryl iodides into the corresponding benzotrifluorides in high yields under mild, base-free conditions in the presence of catalytic quantities of a Cu(I)/1,10-phenanthroline complex.
authors.affiliation: Fachbereich Organische Chemie, TU-Kaiserslautern, Kaiserslautern, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Knauber
authors.forename: Fatih
authors.initials: F
authors.lastname: Arikan
authors.forename: Gerd-Volker
authors.initials: GV
authors.lastname: Röschenthaler
authors.forename: Lukas J
authors.initials: LJ
authors.lastname: Goossen