title: Endoscopic diagnosis and treatment of gastric glomus tumors.
abstract: BACKGROUND
  Although gastric glomus tumors are usually benign lesions, occasional malignant transformation has been reported. Thus, complete resection of the gastric glomus tumor is necessary.
  
  
  OBJECTIVE
  To provide a better understanding of the endoscopic features of this rare entity with an emphasis on its diagnosis and treatment.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Academic medical center.
  
  
  METHODS
  Six patients (2 men, 4 women; median age 48 years) received a diagnosis of gastric glomus tumor and were treated.
  
  
  METHODS
  Endoscopic diagnosis and resection.
  
  
  METHODS
  Endoscopic features, resection success, adverse events, and follow-up endoscopy.
  
  
  RESULTS
  Gastric glomus tumors do not exhibit specific features on gastroscopy and EUS that distinguish them from other gastric submucosal tumors. Endoscopic submucosal enucleation was successful in 5 patients. In one patient, the operation had to be discontinued because of significant bleeding during the procedure. The mean tumor size was 19.8±6.2 mm (range 12-30 mm). Perforation occurred in 1 patient and was successfully managed with hemoclips. No local recurrence was observed during follow-up (mean duration 9±5.1 months, range 3-17 months).
  
  
  CONCLUSIONS
  Small number of patients (N=6), limited follow-up, retrospective study.
  
  
  CONCLUSIONS
  Diagnosis of gastric glomus tumors is difficult when based only on features derived from gastroscopy and EUS. Endoscopic submucosal enucleation is a feasible and safe procedure with which to diagnose and treat this lesion. However, further investigation and comparative studies are required to confirm the safety and efficacy of this method.
authors.affiliation: Institute of Endoscopy, Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Pinghong
authors.initials: P
authors.lastname: Zhou
authors.forename: Meidong
authors.initials: M
authors.lastname: Xu
authors.forename: Weifeng
authors.initials: W
authors.lastname: Chen
authors.forename: Quanlin
authors.initials: Q
authors.lastname: Li
authors.forename: Yuan
authors.initials: Y
authors.lastname: Ji
authors.forename: Liqing
authors.initials: L
authors.lastname: Yao
mesh_terms: D003937:Diagnosis, Differential; D004210:Dissection / Q000379:methods*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology / Q000601:surgery*; D005918:Glomus Tumor / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000601:surgery