title: Rh(III)-catalyzed directed C-H olefination using an oxidizing directing group: mild, efficient, and versatile.
abstract: An efficient Rh(III)-catalyzed oxidative olefination by directed C-H bond activation of N-methoxybenzamides is reported. In this mild, practical, selective, and high-yielding process, the N-O bond acts as an internal oxidant. In addition, simply changing the substituent of the directing/oxidizing group results in the selective formation of valuable tetrahydroisoquinolinone products.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Münster, Germany.
authors.forename: Souvik
authors.initials: S
authors.lastname: Rakshit
authors.forename: Christoph
authors.initials: C
authors.lastname: Grohmann
authors.forename: Tatiana
authors.initials: T
authors.lastname: Besset
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001549:Benzamides; D012238:Rhodium