title: Recent developments in the total synthesis of fungicidal natural products--a crop protection perspective.
abstract: Natural products play an important role as lead structures for the identification of novel active ingredients in crop protection. As it is the case in the pharmaceutical industry, however, many crop protection companies have substantially decreased their in-house efforts in natural product exploration. Therefore, joint projects with academic research groups become more and more important in the field. This review describes several examples for successful collaborations in the field of fungicidal natural products.
authors.affiliation: Bayer Cropscience AG, Alfred-Nobel-Strasse 50, D-40789 Monheim am Rhein, Germany. carlfriedrich.nising@bayer.com
authors.forename: Carl F
authors.initials: CF
authors.lastname: Nising
authors.forename: Stefan
authors.initials: S
authors.lastname: Hillebrand
authors.forename: Lars
authors.initials: L
authors.lastname: Rodefeld
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004345:Drug Industry; D036341:Intercellular Signaling Peptides and Proteins; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011090:Polyenes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011753:Pyrones / Q000138:chemical synthesis / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D000935:Antifungal Agents; D001688:Biological Products; D019086:Bridged Bicyclo Compounds, Heterocyclic; D036341:Intercellular Signaling Peptides and Proteins; D009705:Nucleosides; D010455:Peptides; D011090:Polyenes; D011753:Pyrones; C406052:belactosin A; C089608:crocacin; C493874:malayamycin A; C088446:pironetin