title: Actuality of juvenile dermatomyositis.
abstract: Juvenile dermatomyositis is a rare disorder, but remains the most commonly occurring chronic inflammatory myopathy among children. Other than the proximal muscles and skin, which are routinely affected, vasculopathy may affect other viscera and can be multisystemic. A redefinition of the diagnostic criteria is currently underway and is likely to lead to other clinical signs and to sensitive and non-invasive examinations such as MRI. The impact of juvenile dermatomyositis on health and quality of life remains significant despite systemic corticosteroid therapy and immunosuppressor treatment, which have considerably improved the prognosis. Numerous predictors for favourable and pejorative evolution have been identified. The standardisation and the generalisation of clinical assessment tools will make it possible to carry out the clinical trials required to determine the relevance of the new therapeutic options available for children.
authors.affiliation: Service de Pédiatrie, Hôpital Mère-Enfant, CHU Hassan II, route de Sidi Hrazem, 30000 Fez, Morocco. amine.zouagui@gmail.com
authors.forename: Amine
authors.initials: A
authors.lastname: Zouagui
authors.forename: Sana
authors.initials: S
authors.lastname: Abourazzak
authors.forename: Mounia Lakhdar
authors.initials: ML
authors.lastname: Idrissi
authors.forename: Fatima Zohra
authors.initials: FZ
authors.lastname: Souilmi
authors.forename: Sana
authors.initials: S
authors.lastname: Chaouki
authors.forename: Samir
authors.initials: S
authors.lastname: Atmani
authors.forename: Abdelhak
authors.initials: A
authors.lastname: Bouharrou
authors.forename: Moustapha
authors.initials: M
authors.lastname: Hida
mesh_terms: D001175:Arthrography; D002648:Child; D003882:Dermatomyositis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006304:Health Status; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D011379:Prognosis; D011788:Quality of Life; D012737:Sex Factors; D012867:Skin / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents