title: [Fibroblasts--known or unknown cells].
abstract: Fibroblasts form the main component of the cell tissue microenvironment, and their basic function is to maintain cell integrity and tissue homeostasis. Fibroblasts essentially participate in wound repair. Recently, increased interest has been focused on the role of fibroblasts in cancers, where they are involved in the ransformation of a tumour stroma, and via production of numbers of cytokines and growth factors participate in tumour progression. With regard to their impact in cancerogenesis, fibroblasts become a new target of cancer therapy.
authors.affiliation: Laborator molekulárni patologie a Ustav patologie LF UP, Olomouc. Svetlana.Brychtova@seznam.cz
authors.forename: S
authors.initials: S
authors.lastname: Brychtová
authors.forename: M
authors.initials: M
authors.lastname: Bezdeková
authors.forename: T
authors.initials: T
authors.lastname: Brychta
mesh_terms: D005347:Fibroblasts / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology*; D014945:Wound Healing / Q000502:physiology