title: [The model of the two-hit of Knudson applies to the auto-immune diseases: the example of the lymphoproliferative syndrome with auto-immunity].
authors.forename: Aude
authors.initials: A
authors.lastname: Magerus-Chatinet
authors.forename: Frédéric
authors.initials: F
authors.lastname: Rieux-Laucat
mesh_terms: D017209:Apoptosis; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D056735:Autoimmune Lymphoproliferative Syndrome / Q000209:etiology / Q000235:genetics / Q000276:immunology; D002478:Cells, Cultured / Q000276:immunology / Q000473:pathology; D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics / Q000648:ultrastructure; D004843:Epistasis, Genetic; D053222:Fas Ligand Protein / Q000502:physiology; D005838:Genotype; D018095:Germ-Line Mutation; D006801:Humans; D008957:Models, Genetic; D018448:Models, Immunological; D019683:Penetrance; D016176:T-Lymphocyte Subsets / Q000276:immunology; D019014:fas Receptor / Q000172:deficiency / Q000235:genetics / Q000502:physiology
chemical_list: C505661:FASLG protein, human; D053222:Fas Ligand Protein; D019014:fas Receptor