title: [Detection of BK virus infection in renal transplant recipients and clinical application].
abstract: OBJECTIVE
  To study the detection methods of BK virus infection in kidney transplant recipients, and to explore the clinical application.
  
  
  METHODS
  132 cases of renal transplant recipients were undertaken BK virus detection including presence of decoy cells in urinary sediment, urine and serum BKV-DNA to demonstrate the BK virus replication.
  
  
  RESULTS
  Among 132 cases of renal transplant recipients, urinary decoy cell was found in 37 (28.0%) patients and the median time was 12 months after surgery. 32 (24.2%) patients were diagnosed as BK viruria at a median of 11 months after surgery, and 16 (12.1%) recipients were diagnosed as BK viremia at a median of 15 months after surgery, 5 patients with BK viruria were diagnosed as BK virus associated nephropathy according to allograft biopsy.
  
  
  CONCLUSIONS
  To make early diagnosis of BK virus infection, detection of urine decoy cells and BKV-DNA in urine and plasma sample is important,which provides an important basis for the prevention of BK virus associated nephropathy.
authors.affiliation: The First People's Hospital of Wenling, Zhejiang 317500, China.
authors.forename: Zhong-biao
authors.initials: ZB
authors.lastname: Wu
authors.forename: Guo-bing
authors.initials: GB
authors.lastname: Lin
authors.forename: Ai-ping
authors.initials: AP
authors.lastname: Zeng
authors.forename: Zhen-qian
authors.initials: ZQ
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Min-qiao
authors.initials: MQ
authors.lastname: Zheng
authors.forename: Guo-wei
authors.initials: GW
authors.lastname: Tu
authors.forename: Rui-ming
authors.initials: RM
authors.lastname: Rong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001739:BK Virus / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D005260:Female; D006801:Humans; D007668:Kidney / Q000821:virology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D027601:Polyomavirus Infections / Q000175:diagnosis / Q000821:virology*; D011183:Postoperative Complications / Q000175:diagnosis / Q000821:virology*; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000821:virology*; D014779:Virus Replication; D055815:Young Adult