title: Gingival and dermal fibroblasts: their similarities and differences revealed from gene expression.
abstract: Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost identical, but 5% of their genes were uniquely expressed. These results help us to choose an optimal cell source for effective fibroblast-based cell therapy that is dependent on differential gene expression profiles.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.
authors.forename: Katsumi
authors.initials: K
authors.lastname: Ebisawa
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kato
authors.forename: Mai
authors.initials: M
authors.lastname: Okada
authors.forename: Tomotaka
authors.initials: T
authors.lastname: Sugimura
authors.forename: Mazlyzam Abdul
authors.initials: MA
authors.lastname: Latif
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hori
authors.forename: Yuji
authors.initials: Y
authors.lastname: Narita
authors.forename: Minoru
authors.initials: M
authors.lastname: Ueda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Honda
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kagami
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D005260:Female; D005347:Fibroblasts / Q000378:metabolism*; D020869:Gene Expression Profiling; D005881:Gingiva / Q000166:cytology*; D006801:Humans; D007335:Insulin-Like Growth Factor II / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D020411:Oligonucleotide Array Sequence Analysis; D012867:Skin / Q000166:cytology*
chemical_list: C035170:IGF2 protein, human; D007335:Insulin-Like Growth Factor II