title: [Microbial biofilm in rhinosinusitis and cystic fibrosis].
abstract: Microbial biofilms are known to cause persistent foreign-body infections and have recently been acknowledged as involved in more than 65% of all human infections. Microbial biofilms have been detected in chronic rhinosinusitis, and chronic rhinosinusitis is mandatory in patients with cystic fibrosis. We believe that a reservoir for a sustained lung infection in these patients might be found in the nasal sinuses, and that the sinuses may act as a reservoir for reinfection after CF-patient lung transplants. Further studies are necessary.
authors.affiliation: Øre-næse-halskirurgisk Klinik og Klinisk Mikrobiologisk Afdeling, Rigshospitalet, Denmark. J-fisker@dadlnet.dk
authors.forename: Jacob
authors.initials: J
authors.lastname: Fisker
authors.forename: Christian
authors.initials: C
authors.lastname: von Buchwald
authors.forename: Helle Krogh
authors.initials: HK
authors.lastname: Johansen
mesh_terms: D018441:Biofilms / Q000254:growth & development; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications / Q000382:microbiology*; D006801:Humans; D008168:Lung / Q000382:microbiology; D010256:Paranasal Sinuses / Q000382:microbiology; D018410:Pneumonia, Bacterial / Q000209:etiology / Q000382:microbiology; D012220:Rhinitis / Q000150:complications / Q000382:microbiology*; D012852:Sinusitis / Q000150:complications / Q000382:microbiology*