title: Beliefs about cancer and diet among those considering genetic testing for colon cancer.
abstract: OBJECTIVE
  To assess beliefs about the role of diet in cancer prevention among individuals considering genetic testing for Lynch Syndrome.
  
  
  METHODS
  Family-centered, cascade recruitment; baseline assessment of a longitudinal study.
  
  
  METHODS
  Clinical research setting.
  
  
  METHODS
  Participants were 390 persons, ages 18 and older, including persons with a Lynch Syndrome-associated cancer and suspected of carrying a disease causing mutation, and relatives at risk for inheriting a previously identified mutation.
  
  
  METHODS
  Assess clustering of beliefs about the role of diet in cancer prevention and predictors of class membership.
  
  
  METHODS
  Confirmatory factor analysis; 2-class factor mixture model with binary indicators; multilevel regression analyses, individuals nested within families.
  
  
  RESULTS
  Women endorsed a relationship between diet and cancer prevention more often than men (P < .01). A 2-class model was used where Class 1 indicated less likely to link cancer to diet, and Class 2 indicated more likely. Factors associated with increased odds of membership in Class 1 expressed belief that nothing can prevent cancer (P < .01) and fate attribution (P < .01); Class 2 mentioned personal cancer history (P < .05) and genetic knowledge (P < .01).
  
  
  CONCLUSIONS
  Identifying factors associated with a belief in cancer prevention through dietary behaviors can inform targeted interventions.
authors.affiliation: MacMillan Center, Yale University, New Haven, CT 06520, USA. aunchalee.palmquist@yale.edu
authors.forename: Aunchalee E L
authors.initials: AE
authors.lastname: Palmquist
authors.forename: Rachel
authors.initials: R
authors.lastname: Upton
authors.forename: Seungjin
authors.initials: S
authors.lastname: Lee
authors.forename: Abby T
authors.initials: AT
authors.lastname: Panter
authors.forename: Don W
authors.initials: DW
authors.lastname: Hadley
authors.forename: Laura M
authors.initials: LM
authors.lastname: Koehly
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000517:prevention & control; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000517:prevention & control* / Q000523:psychology*; D004032:Diet; D005163:Factor Analysis, Statistical; D005260:Female; D005638:Fruit; D005820:Genetic Testing; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012737:Sex Factors; D011795:Surveys and Questionnaires; D014675:Vegetables; D055815:Young Adult