title: Distribution of HLA alleles and haplotypes in the Maldivian population.
abstract: The study of human leukocyte antigen (HLA), allele and haplotype frequencies within populations provides an important source of information for anthropological investigation, organ and hematopoietic stem-cell transplantation purposes as well as disease association studies. As of today, there are no data available in the literature on the HLA structure of the Maldivian population. Altogether 106 families were studied. We used the parents of each family (212 unrelated individuals) to analyze the frequencies of HLA class I and class II allele groups and haplotypes.
authors.affiliation: Laboratorio di Immunogenetica e Biologia dei Trapianti, Fondazione IME, Policlinico di Tor Vergata, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Testi
authors.forename: S
authors.initials: S
authors.lastname: Lai
authors.forename: S
authors.initials: S
authors.lastname: Orrù
authors.forename: F
authors.initials: F
authors.lastname: Alba
authors.forename: L
authors.initials: L
authors.lastname: Cappai
authors.forename: N
authors.initials: N
authors.lastname: Firdous
authors.forename: J
authors.initials: J
authors.lastname: Gaziev
authors.forename: M
authors.initials: M
authors.lastname: Troiano
authors.forename: M
authors.initials: M
authors.lastname: Andreani
authors.forename: C
authors.initials: C
authors.lastname: Carcassi
mesh_terms: D000483:Alleles; D004252:DNA Mutational Analysis; D005190:Family; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes; D006650:Histocompatibility Testing; D006801:Humans; D007195:Indian Ocean Islands; D015810:Linkage Disequilibrium; D017422:Sequence Analysis, DNA; D013789:Thalassemia / Q000235:genetics
chemical_list: D006680:HLA Antigens