title: Highly selective insertion of arynes into a C(sp)-O(sp3) σ bond.
abstract: Arynes react with ethoxyacetylene to afford 2-ethoxyethynylaryl derivatives through a highly chemo- and regioselective formal insertion of the aryne into the C(sp)-O(sp(3)) bond of the alkyne. Computational studies suggest that the reaction does not proceed through a mechanism initiated by the nucleophilic addition of the oxygen atom to the aryne as previously proposed but by the addition of the triple bond of the alkyne to the aryne.
authors.affiliation: Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
authors.forename: Krzysztof Z
authors.initials: KZ
authors.lastname: Laczkowski
authors.forename: Diego
authors.initials: D
authors.lastname: García
authors.forename: Diego
authors.initials: D
authors.lastname: Peña
authors.forename: Agustín
authors.initials: A
authors.lastname: Cobas
authors.forename: Dolores
authors.initials: D
authors.lastname: Pérez
authors.forename: Enrique
authors.initials: E
authors.lastname: Guitián