title: Intimal sarcoma of the superficial femoral artery with osteosarcomatous differentiation.
abstract: Sarcomas of the large vessels usually present centrally in the aorta, pulmonary artery, and inferior vena cava. Peripheral arterial sarcomas are exceptionally rare. They have been reported in the iliac and common or profunda femoral arteries, and are frequently undifferentiated. In this study, we describe a differentiated intimal sarcoma of the superficial femoral artery with abundant osteosarcoma within the specimen. Before knowing the diagnosis, treatment was for a presumed pseudoaneurysm using excision and bypass. Postoperatively, the patient received palliative radiation therapy. The tumor's location and histopathology are unique. A differentiated intimal sarcoma has never been reported in the superficial femoral artery, and it represents the second peripheral arterial intimal sarcoma reported with osteosarcomatous differentiation.
authors.affiliation: Boston VA Healthcare System, Surgical Service, West Roxbury, MA 02132, USA. james.ebaugh2@med.va.gov
authors.forename: James L
authors.initials: JL
authors.lastname: Ebaugh
authors.forename: Minsheng
authors.initials: M
authors.lastname: Yuan
authors.forename: Jeffery
authors.initials: J
authors.lastname: Hu
authors.forename: Ahchean
authors.initials: A
authors.lastname: Chen
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Raffetto
mesh_terms: D000369:Aged, 80 and over; D017541:Aneurysm, False / Q000175:diagnosis; D001706:Biopsy; D002454:Cell Differentiation; D003951:Diagnostic Errors; D017809:Fatal Outcome; D005263:Femoral Artery / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D018810:Magnetic Resonance Angiography; D012516:Osteosarcoma / Q000473:pathology* / Q000628:therapy; D010166:Palliative Care; D018714:Radiotherapy, Adjuvant; D012509:Sarcoma / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome; D017539:Tunica Intima / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D019043:Vascular Neoplasms / Q000473:pathology* / Q000628:therapy; D014656:Vascular Surgical Procedures