title: Irradiation stability of folic Acid in powder and aqueous solution.
abstract: This study attempts to examine the folic acid stability after irradiation treatment, under different physical states, pH values, and atmosphere conditions. Aqueous folic acid samples, folic acid in powder, and wheat flour fortified with folic acid were irradiated by an electron beam (E-beam) between 0 (control) and 10.0 kGy. It was realized that the physical state of folic acid plays an important role on its stability toward E-beam processing, being largely unstable in solution, no matter the pH and atmosphere conditions assayed. Otherwise, folic acid in powder showed huge irradiation stability, even when mixed in a dry food matrix, such as fortified wheat flour samples.
authors.affiliation: Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP) , Centro de Tecnologia das Radiações, Av. Prof. Lineu Prestes, 2242, 05508-910, São Paulo, Brazil.
authors.forename: Michel M
authors.initials: MM
authors.lastname: Araújo
authors.forename: Eric
authors.initials: E
authors.lastname: Marchioni
authors.forename: Martine
authors.initials: M
authors.lastname: Bergaentzle
authors.forename: Minjie
authors.initials: M
authors.lastname: Zhao
authors.forename: Florent
authors.initials: F
authors.lastname: Kuntz
authors.forename: Emeline
authors.initials: E
authors.lastname: Hahn
authors.forename: Anna Lucia C H
authors.initials: AL
authors.lastname: Villavicencio
mesh_terms: D004355:Drug Stability; D005433:Flour / Q000032:analysis; D005492:Folic Acid / Q000737:chemistry / Q000528:radiation effects*; D005514:Food Irradiation / Q000009:adverse effects*; D005527:Food, Fortified / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D012996:Solutions; D014867:Water
chemical_list: D012996:Solutions; D014867:Water; D005492:Folic Acid