title: Synthesis of functionalized arylpyridines and -pyrimidines by domino [4+2]/retro [4+2] cycloadditions of electron-rich dienes with alkynylpyridines and -pyrimidines.
abstract: Aryl-substituted pyridines and pyrimidines were prepared by [4+2] cycloadditions of alkynyl-substituted pyridines and -pyrimidines with electron-rich dienes. The reactions proceed by formation of a bridged cycloadduct and subsequent thermal extrusion of ethylene. The pyridine moiety plays a crucial role for the success of the reaction.
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059, Rostock, Germany.
authors.forename: Obaid-ur-Rahman
authors.initials: OU
authors.lastname: Abid
authors.forename: Muhammad
authors.initials: M
authors.lastname: Nawaz
authors.forename: Muhammad Farooq
authors.initials: MF
authors.lastname: Ibad
authors.forename: Rasheed Ahmad
authors.initials: RA
authors.lastname: Khera
authors.forename: Viktor
authors.initials: V
authors.lastname: Iaroshenko
authors.forename: Peter
authors.initials: P
authors.lastname: Langer
mesh_terms: D003500:Cyclization; D004583:Electrons; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*
chemical_list: D011725:Pyridines; D011743:Pyrimidines