title: Genetic risk profiling for prediction of type 2 diabetes.
abstract: Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions.
authors.affiliation: Erasmus University Medical Center Rotterdam; Massachusetts General Hospital and Dept. of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
authors.forename: Raluca
authors.initials: R
authors.lastname: Mihaescu
authors.forename: James
authors.initials: J
authors.lastname: Meigs
authors.forename: Eric
authors.initials: E
authors.lastname: Sijbrands
authors.forename: A Cecile
authors.initials: AC
authors.lastname: Janssens