title: Neuroimaging in psychiatric disorders.
abstract: In psychiatry, neuroimaging facilitates the diagnosis of psychiatric disorders and the development of new medications. It is used to detect structural lesions causing psychosis and to differentiate depression from neurodegenerative disorders or brain tumors. Functional neuroimaging, mostly in the form of molecular neuroimaging with positron emission tomography or single photon emission tomography, facilitates the identification of therapeutic targets, the determination of the dose of a new drug needed to occupy its target in the brain, and the selection of patients for clinical trials.
authors.affiliation: Section on Integrative Neuroimaging, Intramural Research Program, National Institutes of Health (NIH/NIMH-CBDB), Bethesda, Maryland 20892-1365, USA. masdeu@nih.gov
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Masdeu
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging / Q000379:methods* / Q000639:trends; D055808:Drug Discovery / Q000379:methods / Q000639:trends; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D049268:Positron-Emission Tomography; D015899:Tomography, Emission-Computed, Single-Photon