title: RNA seeds nuclear bodies.
abstract: The interior of the eukaryotic cell nucleus is populated by a multitude of microscopic domains termed nuclear bodies. Despite having attracted much attention, how these compartments form and are maintained remained elusive. Now, two live-cell imaging studies provide compelling evidence that nascent RNAs can act as transiently immobilized scaffolds that recruit specific nuclear body proteins.
authors.affiliation: Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. carmo.fonseca@fm.ul.pt
authors.forename: Maria
authors.initials: M
authors.lastname: Carmo-Fonseca
authors.forename: José
authors.initials: J
authors.lastname: Rino
mesh_terms: D001681:Biological Assay / Q000379:methods; D002467:Cell Nucleus / Q000648:ultrastructure*; D045586:Intranuclear Inclusion Bodies / Q000235:genetics* / Q000378:metabolism*; D008954:Models, Biological; D015138:RNA, Nuclear / Q000378:metabolism*
chemical_list: D015138:RNA, Nuclear