title: Differential expression of microRNA-206 in skeletal muscle of female Piedmontese and Friesian cattle.
abstract: The double-muscle phenotype is an inherited condition in Piedmontese cattle traced to a point mutation in the myostatin gene. To investigate the potential role of muscle-specific miRNAs in determining muscle development in cattle, this study examined the patterns of expression of microRNAs (miRNA-1) and miRNA-206 in Piedmontese and Friesian cattle according to phenotype and sex. There were no significant differences in miRNA-1 expression between different muscle phenotypes, sexes or breeds, whereas there was significantly higher expression of miRNA-206 in female Piedmontese compared with female Friesian cattle.
authors.affiliation: Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, 10095 Torino, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Miretti
authors.forename: Eugenio
authors.initials: E
authors.lastname: Martignani
authors.forename: Riccardo
authors.initials: R
authors.lastname: Taulli
authors.forename: Francesca
authors.initials: F
authors.lastname: Bersani
authors.forename: Paolo
authors.initials: P
authors.lastname: Accornero
authors.forename: Mario
authors.initials: M
authors.lastname: Baratta
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics*; D005260:Female; D008297:Male; D035683:MicroRNAs / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism*; D010641:Phenotype; D012737:Sex Factors; D013045:Species Specificity
chemical_list: D035683:MicroRNAs