title: Preparation and chiral recognition in HPLC of cellulose 3,5-dichlorophenylcarbamates immobilized onto silica gel.
abstract: The 3,5-dichlorophenylcarbamates (2) of cellulose bearing a small amount of 3-(triethoxysilyl)propyl residues were synthesized by a one-pot process and immobilized onto a silica gel through intermolecular polycondensation of the triethoxysilyl groups. The obtained cellulose derivatives were characterized by (1) H NMR and elemental analysis (EA), and their recognition abilities were evaluated by high-performance liquid chromatography (HPLC). The cellulose derivatives containing about 1-5% of the 3-(triethoxysilyl)propyl residue were efficiently immobilized with a high chiral recognition ability. The immobilized chiral packing materials (CPMs) could be used with the eluents containing chloroform and tetrahydrofuran (THF), which cannot be used with the conventional coated-type chiral packing materials. By using these eluents, the chiral recognition for many racemates was improved.
authors.affiliation: Polymer Materials Research Center, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin, PR China.
authors.forename: Hai-tao
authors.initials: HT
authors.lastname: Qu
authors.forename: Jun-qing
authors.initials: JQ
authors.lastname: Li
authors.forename: Guang-shun
authors.initials: GS
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Shen
authors.forename: Xian-de
authors.initials: XD
authors.lastname: Shen
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okamoto
mesh_terms: D000327:Adsorption; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D048448:Phenylcarbamates / Q000737:chemistry*; D058428:Silica Gel / Q000737:chemistry*
chemical_list: D048448:Phenylcarbamates; C420325:cellulose tris(3,5-dichlorophenylcarbamate); D058428:Silica Gel; D002482:Cellulose