title: The combination of body mass index and age as a new index for identifying osteoporosis in Thai postmenopausal women.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the application of the combination of bone mass index (BMI) and age as a new screening tool to identify osteoporosis in Thai postmenopausal women.
  
  
  METHODS
  Diagnostic study.
  
  
  METHODS
  Bone mineral density (BMD) data of Thai postmenopausal women, age 40-80 years old who attended the outpatient clinic, Thammasat University Hospital, Thailand, between January 2004 and December 2008 were enrolled. The participants with history of metabolic bone disease or use of drugs associated with secondary osteoporosis and/or history of treatment for osteoporosis were excluded. Each had BMD records of lumbar spine, femoral neck and intertrochanter. The data were completely collected in all 372 women. A diagnosis of osteoporosis made according to WHO criteria.
  
  
  RESULTS
  The prevalence of osteoporosis at lumbar spine, femoral neck and intertrochanter were 8.1%, 20.2% and 15.3% respectively. The combination of BMI and age as the index to detect osteoporosis had a sensitivity at 76.67%, 76% and 77.19%, respectively. The OSTA index at the standard cut-point of -1 had a sensitivity at 80%, 70.67% and 70.17%, respectively. Raising the cut-point to < or =0 would had a sensitivity at 90%, 85.33% and 78.95%, respectively.
  
  
  CONCLUSIONS
  The application of the combination of BMI and age as a screening tool is another option to identify osteoporosis in Thai postmenopausal women. Change the cut-point of < or =0, OSTA index could improve the detection of osteoporosis at a very high level of the sensitivity.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand. C.Tanprasertkul@gmail.com
authors.forename: Chamnan
authors.initials: C
authors.lastname: Tanprasertkul
authors.forename: Pisit
authors.initials: P
authors.lastname: Wattanaruangkowit
authors.forename: Krasean
authors.initials: K
authors.lastname: Panyakhamlerd
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D015992:Body Mass Index; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis* / Q000453:epidemiology / Q000208:ethnology; D011237:Predictive Value of Tests; D015995:Prevalence; D012372:ROC Curve; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology