title: Dynamic contrast-enhanced MRI of primary rectal cancer: quantitative correlation with positron emission tomography/computed tomography.
abstract: OBJECTIVE
  To assess the correlations between parameters measured on dynamic contrast-enhanced magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in rectal cancer.
  
  
  METHODS
  To assess the correlations between parameters measured on dynamic contrast-enhanced MRI and FDG-PET in rectal cancer.
  
  
  RESULTS
  Significant correlations were only demonstrated between k(ep) and SUVmax (r = 0.587, P = 0.001), and k(ep) and SUVmean (r = 0.562, P = 0.002). No significant differences were found in imaging parameters between well, moderately and poorly differentiated adenocarcinoma groups. However, there was a trend that higher imaging values were found in poorly differentiated adenocarcinomas.
  
  
  CONCLUSIONS
  Positive correlations were found between k(ep) and SUV values in primary rectal adenocarcinomas suggesting an association between angiogenesis and metabolic activity and further reflecting that angiogenic activity in washout phase is better associated with tumor metabolism than the uptake phase.
authors.affiliation: Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
authors.forename: Jing
authors.initials: J
authors.lastname: Gu
authors.forename: Pek-Lan
authors.initials: PL
authors.lastname: Khong
authors.forename: Silun
authors.initials: S
authors.lastname: Wang
authors.forename: Queenie
authors.initials: Q
authors.lastname: Chan
authors.forename: Ed X
authors.initials: EX
authors.lastname: Wu
authors.forename: Wailun
authors.initials: W
authors.lastname: Law
authors.forename: Rico Kingyin
authors.initials: RK
authors.lastname: Liu
authors.forename: Jingbo
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D019788:Fluorodeoxyglucose F18; D006571:Heterocyclic Compounds; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012004:Rectal Neoplasms / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate