title: Comparison of diagnostic accuracy of saline infusion sonohysterography, transvaginal sonography and hysteroscopy.
abstract: We aimed to compare the accuracy of transvaginal sonography (TVS), saline infusion sonohysterography (SIS) and hysteroscopy (HS) for uterine pathologies among infertile women. A total of 346 patients were selected for operative hysteroscopy, following SIS after TVS. SİS was performed with a Cook Soft 500 IVF catheter. Sensitivity, specificity, positive and negative predictive values (PPV, NPV) were calculated to compare the accuracy of TVS, SIS and hysteroscopy for uterine abnormalities. SIS showed a sensitivity of 87%, specificity of 100% and PPV of 100% for endometrial hyperplasia, and a sensitivity and NPV of 100% for polypoid lesions. For submucosal myoma SIS showed a sensitivity of 99% with PPV of 96%. Hysteroscopy had a sensitivity, specificity, PPV and NPV of 98%, 83%, 96% and 91%, respectively for overall uterine pathologies. Finally, SIS seems to be superior to TVS, for uterine pathologies, with respect to hysteroscopy as the gold standard.
authors.affiliation: Gayrettepe Florence Nightingale Hospital, Istanbul Bilim University, Istanbul, Turkey. banubingol1975@yahoo.com
authors.forename: B
authors.initials: B
authors.lastname: Bingol
authors.forename: Z
authors.initials: Z
authors.lastname: Gunenc
authors.forename: A
authors.initials: A
authors.lastname: Gedikbasi
authors.forename: H
authors.initials: H
authors.lastname: Guner
authors.forename: S
authors.initials: S
authors.lastname: Tasdemir
authors.forename: B
authors.initials: B
authors.lastname: Tiras
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods / Q000592:standards*; D007247:Infertility, Female / Q000000981:diagnostic imaging* / Q000473:pathology*; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000473:pathology; D008595:Menorrhagia / Q000000981:diagnostic imaging / Q000473:pathology; D011127:Polyps / Q000000981:diagnostic imaging / Q000473:pathology; D011237:Predictive Value of Tests; D011247:Pregnancy; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012965:Sodium Chloride; D014463:Ultrasonography / Q000379:methods / Q000592:standards*; D014591:Uterine Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014621:Vagina
chemical_list: D012965:Sodium Chloride