title: Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.
abstract: Metabolomics involves the identification and quantification of metabolites present in a biological system. Three different approaches can be used: metabolomic fingerprinting, metabolic profiling, and metabolic footprinting, in order to evaluate the clinical course of a disease, patient recovery, changes in response to surgical intervention or pharmacological treatment, as well as other associated features. Characteristic patterns of metabolites can be revealed that broaden our understanding of a particular disorder. In the present paper, common strategies and analytical techniques used in metabolomic studies are reviewed, particularly with reference to the cardiovascular field.
authors.affiliation: Department of Vascular Physiopathology, Hospital Nacional de Paraplejicos, SESCAM, 45071 Toledo, Spain.
authors.forename: Maria G
authors.initials: MG
authors.lastname: Barderas
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Laborde
authors.forename: Maria
authors.initials: M
authors.lastname: Posada
authors.forename: Fernando
authors.initials: F
authors.lastname: de la Cuesta
authors.forename: Irene
authors.initials: I
authors.lastname: Zubiri
authors.forename: Fernando
authors.initials: F
authors.lastname: Vivanco
authors.forename: Gloria
authors.initials: G
authors.lastname: Alvarez-Llamas
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000378:metabolism*; D006801:Humans; D055432:Metabolomics / Q000379:methods*
chemical_list: D015415:Biomarkers