title: FDG PET/CT imaging suggests lymphoma involving prostate may be more resistant to treatment.
abstract: FDG PET imaging is generally not useful for prostate cancer. Nevertheless, incidental intense FDG uptake in the prostate warrants further evaluation to assess for prostatic malignancy. We report a case where intense FDG uptake was incidentally noted in an enlarged prostate on FDG PET/CT scan performed for a large left hilar/mediastinal mass (that was also intensely FDG avid along with several additional FDG-avid lesions elsewhere). Biopsy of the prostate and mediastinal lesions revealed large B-cell non-Hodgkin lymphoma at both sites. Serial FDG PET/CT imaging in this patient revealed that the prostatic lymphomatous lesions showed a slower and incomplete response to chemotherapy compared with other sites of lymphomatous involvement (that showed a rapid and complete response to chemotherapy) in the same patient.
authors.affiliation: PET Imaging Center, Biomedical Research Foundation of Northwest Louisiana, Shreveport, LA 71105, USA.
authors.forename: Geming
authors.initials: G
authors.lastname: Li
authors.forename: Manish
authors.initials: M
authors.lastname: Dhawan
authors.forename: Amol M
authors.initials: AM
authors.lastname: Takalkar
authors.forename: David L
authors.initials: DL
authors.lastname: Lilien
mesh_terms: D019008:Drug Resistance, Neoplasm; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18