title: Generalized acanthosis nigricans related to type B insulin resistance syndrome: a case report.
abstract: Acanthosis nigricans (AN) is a cutaneous marker for many underlying states such as endocrine abnormality, obesity, certain drugs, and malignancy. Generalized AN is a rare condition and is commonly seen in adults with an underlying malignancy. The type B insulin resistance syndrome, a rare autoimmune disorder, is caused by the autoantibodies to the insulin receptor. Patients typically present with hyperglycemia but also may present with hypoglycemia. We report a rare case of a 36-year-old man with generalized AN and type B insulin resistance syndrome with hypoglycemia.
authors.affiliation: Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.
authors.forename: Ki-Heon
authors.initials: KH
authors.lastname: Jeong
authors.forename: Seung-Joon
authors.initials: SJ
authors.lastname: Oh
authors.forename: Suk
authors.initials: S
authors.lastname: Chon
authors.forename: Mu-Hyoung
authors.initials: MH
authors.lastname: Lee
mesh_terms: D000052:Acanthosis Nigricans / Q000209:etiology* / Q000276:immunology; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007333:Insulin Resistance / Q000276:immunology*; D008297:Male; D013577:Syndrome