title: Parents' perspectives on the unforeseen finding of a fetal sex chromosomal aneuploidy.
abstract: OBJECTIVE
  To investigate the parental perspectives of being confronted with an unforeseen fetal sex chromosomal aneuploidy (SCA), in light of the fact that this accidental finding is avoidable by rapid aneuploidy detection (RAD).
  
  
  METHODS
  Exploratory qualitative interview study. We conducted 16 semi-structured interviews with parents who decided to continue pregnancy after the unforeseen finding of a fetal SCA.
  
  
  RESULTS
  The communication of the unforeseen finding of SCA; the informed decision-making process concerning the pregnancy follow-up and the child and its future were the extracted themes. Parents were not prepared to accidental findings in routine prenatal diagnostics. All started an unguided search on the Internet. It is not at all clear whether parents have preference for an RAD test with X and Y probes Parents were satisfied with the post-test professional information they received to make an informed decision, whereas after birth questions still remained to be answered.
  
  
  CONCLUSIONS
  Parents' perspectives may serve as major contributors to research on the question whether or not the X and Y probes should be standard included for purposes of RAD. The fact that RAD has the possibility to avoid accidental findings of SCAs, brings up the question whether any benefits outweigh the potential harms.
authors.affiliation: Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. j.pieters@obgyn.umcn.nl
authors.forename: J J P M
authors.initials: JJ
authors.lastname: Pieters
authors.forename: A J A
authors.initials: AJ
authors.lastname: Kooper
authors.forename: A J
authors.initials: AJ
authors.lastname: Eggink
authors.forename: C M
authors.initials: CM
authors.lastname: Verhaak
authors.forename: B J
authors.initials: BJ
authors.lastname: Otten
authors.forename: D D M
authors.initials: DD
authors.lastname: Braat
authors.forename: A P T
authors.initials: AP
authors.lastname: Smits
authors.forename: E
authors.initials: E
authors.lastname: van Leeuwen
mesh_terms: D000328:Adult; D000782:Aneuploidy; D001290:Attitude; D003657:Decision Making / Q000502:physiology; D030881:Disclosure; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010290:Parents / Q000523:psychology; D010465:Perception / Q000502:physiology; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods / Q000523:psychology*; D012729:Sex Chromosome Aberrations; D025064:Sex Chromosome Disorders / Q000175:diagnosis / Q000523:psychology; D011795:Surveys and Questionnaires