title: Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea.
abstract: Two unusual human rotavirus G12 strains, CAU195 and CAU214, were isolated from female pediatric diarrhea patients under 12 months of age in 2006 using a cell culture system and their full genome sequences were analyzed. The 11 gene segments of both Korean G12 strains were classified as G12-P[6]-R1-C1-M1-I1-A1-N1-T1-E1-H1 genotypes. Notably, the Korean strains were of the same genotypes as previously reported strains isolated from Bangladesh in 2003 (Dhaka12-03), from the United States in 2005-2006 (US6597), and from Germany in 2008 (GER126-08 and GER172-08), suggesting that closely related G12P[6] strains are persistent and widespread.
authors.affiliation: Department of Microbiology and Research Institute for Translational System Biomics, Chung-Ang University College of Medicine, Seoul, South Korea.
authors.forename: Van Thai
authors.initials: VT
authors.lastname: Than
authors.forename: Van Phan
authors.initials: VP
authors.lastname: Le
authors.forename: Inseok
authors.initials: I
authors.lastname: Lim
authors.forename: Wonyong
authors.initials: W
authors.lastname: Kim
mesh_terms: D001483:Base Sequence; D018929:Cell Culture Techniques; D002460:Cell Line; D005260:Female; D016679:Genome, Viral; D006801:Humans; D007223:Infant; D008969:Molecular Sequence Data; D010802:Phylogeny; D056910:Republic of Korea; D012401:Rotavirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification / Q000502:physiology; D012400:Rotavirus Infections / Q000821:virology*