title: Relationship between energy expenditure, nutritional status and clinical severity before starting enteral nutrition in critically ill children.
abstract: The objective of the present study was to investigate the relationship between energy expenditure (EE), biochemical and anthropometric nutritional status and severity scales in critically ill children. We performed a prospective observational study in forty-six critically ill children. The following variables were recorded before starting nutrition: age, sex, diagnosis, weight, height, risk of mortality according to the Paediatric Risk Score of Mortality (PRISM), the Revised Paediatric Index of Mortality (PIM2) and the Paediatric Logistic Organ Dysfunction (PELOD) scales, laboratory parameters (albumin, total proteins, prealbumin, transferrin, retinol-binding protein, cholesterol and TAG, and nitrogen balance) and EE measured by indirect calorimetry. The results showed that there was no relationship between EE and clinical severity evaluated using the PRISM, PIM2 and PELOD scales or with the anthropometric nutritional status or biochemical alterations. Finally, it was concluded that neither nutritional status nor clinical severity is related to EE. Therefore, EE must be measured individually in each critically ill child using indirect calorimetry.
authors.affiliation: Paediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Dr Castelo 47, Madrid, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Botrán
authors.forename: Jesús
authors.initials: J
authors.lastname: López-Herce
authors.forename: Santiago
authors.initials: S
authors.lastname: Mencía
authors.forename: Javier
authors.initials: J
authors.lastname: Urbano
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Solana
authors.forename: Ana
authors.initials: A
authors.lastname: García
authors.forename: Angel
authors.initials: A
authors.lastname: Carrillo
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D002153:Calorimetry, Indirect; D002648:Child; D002675:Child, Preschool; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness / Q000401:mortality / Q000628:therapy*; D004734:Energy Metabolism; D004750:Enteral Nutrition; D006801:Humans; D007223:Infant; D009752:Nutritional Status; D011446:Prospective Studies; D012306:Risk; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers