title: Autogenous grafts/allografts/conduits for bridging peripheral trigeminal nerve gaps.
abstract: Nerve repairs and grafting techniques have been around for many years. Autogenous nerve grafts have worked reasonably well in the right circumstances but are associated with difficulties in achieving a proper donor-host match and with postsurgical sequelae at the donor site. Vein grafts seem to work almost as well as autogenous nerve grafts in digital nerve repairs that require a graft less than 3 cm in length. Currently, the most promising nerve graft materials are the polyglycolic acid tubes and processed decellularized allografts, which have shown good results without the morbidity of autogenous nerve grafts. However, more research studies using these materials for TN repairs are essential to validate the superiority of these procedures.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Texas A&M University Health Science Center, Baylor College of Dentistry, Dallas, TX, USA. lwolford@swbell.net
authors.forename: Larry M
authors.initials: LM
authors.lastname: Wolford
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Rodrigues
mesh_terms: D020341:Absorbable Implants; D000367:Age Factors; D000714:Anastomosis, Surgical / Q000295:instrumentation / Q000379:methods; D001672:Biocompatible Materials / Q000737:chemistry; D004431:Ear, External / Q000294:innervation; D006801:Humans; D007431:Intraoperative Complications; D008036:Lingual Nerve / Q000601:surgery; D061222:Lingual Nerve Injuries; D008340:Mandibular Nerve / Q000601:surgery; D008866:Microsurgery / Q000295:instrumentation / Q000379:methods; D019635:Neurosurgical Procedures / Q000295:instrumentation / Q000379:methods*; D009915:Orbit / Q000294:innervation; D010525:Peripheral Nerves / Q000637:transplantation*; D011091:Polyesters / Q000737:chemistry; D011100:Polyglycolic Acid / Q000737:chemistry; D019651:Plastic Surgery Procedures / Q000295:instrumentation; D013497:Sural Nerve / Q000033:anatomy & histology / Q000601:surgery; D013536:Suture Techniques; D013997:Time Factors; D054457:Tissue Scaffolds; D020858:Tissue and Organ Harvesting / Q000379:methods; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000601:surgery*; D061221:Trigeminal Nerve Injuries; D014680:Veins / Q000637:transplantation*
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters; D011100:Polyglycolic Acid; C062968:lactide-caprolactone copolymer