title: Lipid patterns in the saliva of smoking young adults.
abstract: Salivary lipids are important for the maintenance of oral cavity health. Elevated salivary lipid levels are associated with an increase of caries incidence, plaque development, calculus formation and periodontal disease. However, the regulation of lipid salivary levels is scarcely known. Cigarette smoke is considered a risk factor for oral cavity diseases. We study how cigarette smoke may affect the secretion of salivary lipids. To this purpose, we determine the salivary levels of cholesterol and of glycerolipids in saliva sampled from smokers and non-smokers at various times of day. We observe an increase of glycerophospholipid and a decrease of cholesterol levels in the smokers' saliva collected at 10 p.m. On the other hand, unsaturated fatty acids in chief phospholipids of saliva are lower in smokers at 7 a.m. Therefore, for the first time, we demonstrate that cigarette smoke induces variations of saliva lipid pattern in young people even moderately smoking.
authors.affiliation: Department of Internal Medicine, Laboratory of Biochemistry, University of Perugia, Perugia, Italy. crlpal@unipg.it
authors.forename: C A
authors.initials: CA
authors.lastname: Palmerini
authors.forename: C
authors.initials: C
authors.lastname: Saccardi
authors.forename: F
authors.initials: F
authors.lastname: Ferracci
authors.forename: S
authors.initials: S
authors.lastname: Arienti
mesh_terms: D000328:Adult; D006801:Humans; D008055:Lipids / Q000032:analysis* / Q000737:chemistry; D008297:Male; D010758:Phosphorus / Q000032:analysis; D012463:Saliva / Q000737:chemistry*; D012907:Smoking / Q000378:metabolism*; D013997:Time Factors; D055815:Young Adult
chemical_list: D008055:Lipids; D010758:Phosphorus