title: [Cytogenetic analysis of material from spontaneous abortion].
abstract: OBJECTIVE
  To describe chromosomal abnormalities in spontaneous abortion material.
  
  
  METHODS
  A retrospective compilation of karyotype analysis of slides stained with Band G was carried out by optical microscopy with materials of 428 abortion products referred for study.
  
  
  RESULTS
  There were 145 normal results (33.9%) and 237 abnormal results (55.4%). In 46 samples there was no cell growth (10.7%). Numerical abnormalities were the most frequent, especially trisomy 16 (41 cases), triplodia (27 cases), monosomy X (26 cases), tetraploidy (13 cases) and trisomy 15 (13 cases).
  
  
  CONCLUSIONS
  Cytogenetic alterations are an important cause of pregnancy loss and their detection helps the genetic counseling to the couple. Trisomy 16 is the most often found change.
authors.affiliation: Grupo Fleury Medicina & Saúde, São Paulo, SP.
authors.forename: Daniel Lorber
authors.initials: DL
authors.lastname: Rolnik
authors.forename: Mário Henrique Burlacchini de
authors.initials: MH
authors.lastname: Carvalho
authors.forename: Ana Lúcia Pereira Monteiro
authors.initials: AL
authors.lastname: Catelani
authors.forename: Ana Paula Almeida Rocha
authors.initials: AP
authors.lastname: Pinto
authors.forename: Juliana Branco Gonçalves
authors.initials: JB
authors.lastname: Lira
authors.forename: Neusa Kiyomi
authors.initials: NK
authors.lastname: Kusagari
authors.forename: Paula
authors.initials: P
authors.lastname: Belline
authors.forename: Maria de Lourdes
authors.initials: Mde L
authors.lastname: Chauffaille
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002869:Chromosome Aberrations / Q000706:statistics & numerical data*; D002885:Chromosomes, Human, Pair 16; D020732:Cytogenetic Analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009030:Mosaicism / Q000706:statistics & numerical data; D011247:Pregnancy; D012189:Retrospective Studies; D014314:Trisomy; D055815:Young Adult