title: Aortic valve reconstruction using self-developed aortic valve plasty system in aortic valve disease.
abstract: Aortic valve disease is usually treated by prosthetic valve replacement. We have performed aortic valve plasty (AVP) using glutaraldehyde-treated autologous pericardium. AVP was performed for 88 patients from April 2007 through August 2009. Sixty-five patients had aortic stenosis, and 23 patients had aortic regurgitation (AR). Twenty-one patients showed bicuspid aortic valves, and one patient showed quadricuspid valve. There were 43 males and 45 females. Their mean age was 70.6±10.5 years old. First, diseased leaflets excised. Then, the distance between each commissure was measured. The new leaflet were trimmed with an original template from a glutaraldehyde-treated autologous pericardium sample. Finally, the annular margin of the pericardial leaflet was running sutured to each annulus. There was no operative mortality or embolic event. Postoperative echocardiography revealed a mean peak pressure gradient (PG) of 19.0±9.1 mmHg one week after surgery. Thirty-two patients had echocardiography one year after surgery. The peak PG became 12.9±5.8 mmHg. Ten patients showed no AR, 20 patients showed trivial AR, and two patients showed mild AR. Freedom from reoperation is 100% at three years follow-up.
authors.affiliation: Department of Cardiovascular Surgery, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro, Tokyo 153-8515, Japan. ozakis@oha.toho-u.ac.jp
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Ozaki
authors.forename: Isamu
authors.initials: I
authors.lastname: Kawase
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yamashita
authors.forename: Shin
authors.initials: S
authors.lastname: Uchida
authors.forename: Yukinari
authors.initials: Y
authors.lastname: Nozawa
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Matsuyama
authors.forename: Mikio
authors.initials: M
authors.lastname: Takatoh
authors.forename: So
authors.initials: S
authors.lastname: Hagiwara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D058385:Cardiac Valve Annuloplasty / Q000009:adverse effects; D005260:Female; D005404:Fixatives; D005976:Glutaral; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D013997:Time Factors; D016707:Tissue Fixation / Q000379:methods; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D005404:Fixatives; D005976:Glutaral