title: Human growth hormone treatment: synthesis of literature on product delivery systems and administration practices.
abstract: OBJECTIVE
  To synthesize current literature on recombinant human growth hormone (rhGH) use and to identify areas of research that have received little to no attention in light of administration practice and patient perception/behavior.
  
  
  METHODS
  Relevant articles for a systematic review were identified through PubMed.
  
  
  RESULTS
  A total of 43 articles were identified: 9 (15.9%) studies on product administration practices and 34 (84.1%) on patient behavior patterns. Patients primarily preferred simple, convenient, and easy-to-use delivery devices. However, literature addressing the effect of convenient product administration practices on treatment outcomes using real-world patient/caregiver data is lacking.
  
  
  CONCLUSIONS
  Better understanding of real-world product administration practices will help nurses identify areas of improvement in patient education and training.
authors.affiliation: I.M.S. Health, Health Economics and Outcomes Research, Falls Church, Virginia, USA.
authors.forename: Monali
authors.initials: M
authors.lastname: Bhosle
authors.forename: David
authors.initials: D
authors.lastname: Klingman
authors.forename: Mark
authors.initials: M
authors.lastname: Aagren
authors.forename: Tami
authors.initials: T
authors.lastname: Wisniewski
authors.forename: Won Chan
authors.initials: WC
authors.lastname: Lee
mesh_terms: D001823:Body Composition / Q000187:drug effects; D001827:Body Height / Q000187:drug effects; D002648:Child; D004334:Drug Administration Schedule; D019317:Evidence-Based Medicine; D006128:Growth / Q000187:drug effects*; D019382:Human Growth Hormone / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D011994:Recombinant Proteins / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D011994:Recombinant Proteins; D019382:Human Growth Hormone