title: A novel preparation of methyl-β-cyclodextrin from dimethyl carbonate and β-cyclodextrin.
abstract: A novel green synthesis process about methyl-β-cyclodextrin has been investigated through the reaction between β-cyclodextrin and dimethyl carbonate by anhydrous potassium carbonate as catalyst in DMF. The influence of experimental factors including the molar ratio of dimethyl carbonate to β-cyclodextrin, reaction temperature, and reaction time on the average degree of substitution of methyl-β-cyclodextrin was studied. The results show that the average degree of substitution of methyl-β-cyclodextrin can be dependent on the reaction temperature and the molar ratio of raw material primarily. The structures of methyl-β-cyclodextrin were characterized by TLC, IR, MS, (1)H NMR, and (13)C NMR.
authors.affiliation: School of Chemical Engineering and Technology, Key Laboratory for Green Chemical Technology of State Education Ministry, Tianjin University, China.
authors.forename: Yongjiang
authors.initials: Y
authors.lastname: Gan
authors.forename: Yimin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Chuanhao
authors.initials: C
authors.lastname: Xiao
authors.forename: Chunyan
authors.initials: C
authors.lastname: Zhou
authors.forename: Yucang
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D002254:Carbonates; D002384:Catalysis; D005561:Formates / Q000737:chemistry*; D006358:Hot Temperature; D011188:Potassium; D012995:Solubility; D047392:beta-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002254:Carbonates; D005561:Formates; D047392:beta-Cyclodextrins; C108732:methyl-beta-cyclodextrin; C037593:potassium carbonate; C023025:methyl carbonate; D011188:Potassium