title: Use of hypothermia for traumatic brain injury: point of view.
abstract: Traumatic brain injury (TBI) is one of the major causes of disability in modern society. The World Health Organization has predicted that, by 2020, traffic accidents will represent the greatest burden of global disease and injury. Brain injury after trauma occurs in two stages. Primary injury is directly associated with the biomechanical effects of the trauma, whereas secondary injury occurs later and can be attributed to processes that develop within the brain. Currently, there is no consensus for the use of hypothermia in the treatment of secondary injury after TBI. Until the results of ongoing studies are published, maintaining normothermia and avoiding hyperthermia should be used in managing patient with TBI.
authors.affiliation: General Anesthesia and Outcomes Research, Cleveland Clinic, Cleveland, OH 44195, USA. farage@ccf.org
authors.forename: E
authors.initials: E
authors.lastname: Farag
authors.forename: E M
authors.initials: EM
authors.lastname: Manno
authors.forename: A
authors.initials: A
authors.lastname: Kurz
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000503:physiopathology / Q000628:therapy*; D003422:Critical Care; D006801:Humans; D007036:Hypothermia, Induced; D007362:Intensive Care Units; D051381:Rats