title: Structure and spectral properties of dinuclear zinc complex containing semicarbazonate ligands.
abstract: The dinuclear Zn(2+) complex [Zn(HSSC)OAc](2)·2DMF (H(2)SSC=salicylaldehyde semicarbazone; HOAc=acetic acid; DMF=N,N-dimethylfomamide) was prepared and structurally characterized by single crystal X-ray. The basic structural unit of the complex is a dinuclear complex [Zn(HSSC)OAc](2) in which the semicarbazone ligand adopts the phenol-imine form. The deprotonated phenol group forms a one-atom bridge between the two zinc centers, and both of the zinc centers are five-coordinated. The local coordination environment of Zn(2+) can be approximately considered as square pyramidal. UV spectral studies show that the H(2)SSC provides strong binding of Zn(2+) in a 1:1 ratio in solution. The conditional binding constant of the complex is lgK(Zn-L)=12.89±0.76 in 0.05M Tris-HCl buffer at pH 7.4. The H(2)SSC exhibits an enhanced fluorescence effect by the addition of Zn(2+), and affords an excellent selectivity for Zn(2+) under physiological conditions.
authors.affiliation: Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Jing-Lin
authors.forename: Feng
authors.initials: F
authors.lastname: Jiao
authors.forename: Xu
authors.initials: X
authors.lastname: Mei-Ping
authors.forename: Yang
authors.initials: Y
authors.lastname: Bin-Sheng
mesh_terms: D018360:Crystallography, X-Ray; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D012664:Semicarbazones / Q000737:chemistry*; D013057:Spectrum Analysis / Q000295:instrumentation / Q000379:methods; D015032:Zinc / Q000737:chemistry*
chemical_list: D008024:Ligands; D012664:Semicarbazones; D015032:Zinc