title: [Photodynamic therapy and prostate cancer].
abstract: OBJECTIVE
  Photodynamic therapy (PDT) is an innovative therapeutic modality in urologic oncology.
  
  
  METHODS
  We reviewed the current literature on principles and modalities of PDT in prostatic oncology.
  
  
  RESULTS
  Focal therapy of prostate cancer is an application field of PDT. Clinical phase II studies are ongoing to determine PDT efficacy and safety in this indication. PDT as salvage treatment after prostatic radiotherapy has been tested. Carcinologic results were promising but important side effects were reported. Individual dosimetric planification is necessary to avoid this toxicity.
  
  
  CONCLUSIONS
  PDT first clinical experience for prostate cancer has showed its technical feasibility. Several research ways are currently in study to improve carcinologic efficacy and to limit potential side effects.
authors.affiliation: Inserm, U703, Université Nord de France, CHRU de Lille, 152, rue du Dr-Yersin, 59120 Loos, France. pierre_colin@msn.com
authors.forename: P
authors.initials: P
authors.lastname: Colin
authors.forename: J-P
authors.initials: JP
authors.lastname: Estevez
authors.forename: N
authors.initials: N
authors.lastname: Betrouni
authors.forename: A
authors.initials: A
authors.lastname: Ouzzane
authors.forename: P
authors.initials: P
authors.lastname: Puech
authors.forename: X
authors.initials: X
authors.lastname: Leroy
authors.forename: J
authors.initials: J
authors.lastname: Biserte
authors.forename: A
authors.initials: A
authors.lastname: Villers
authors.forename: S
authors.initials: S
authors.lastname: Mordon
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D010778:Photochemotherapy; D011471:Prostatic Neoplasms / Q000188:drug therapy*