title: Autogenous transcriptional regulation of the regA gene, encoding an AraC-Like, essential virulence regulator in Citrobacter rodentium.
abstract: We identified several promoters responsible for the expression of regA, which encodes a global virulence regulator in Citrobacter rodentium. Expression of some of the promoters was strongly autoactivated by RegA in conjunction with bicarbonate. Biochemical and mutational analyses were used to determine the consensus sequence of the RegA-binding sites.
authors.affiliation: Department of Microbiology and Immunology, the University of Melbourne, Victoria 3010, Australia.
authors.forename: Aimee
authors.initials: A
authors.lastname: Tan
authors.forename: Ji
authors.initials: J
authors.lastname: Yang
authors.forename: Marija
authors.initials: M
authors.lastname: Tauschek
authors.forename: Judyta
authors.initials: J
authors.lastname: Praszkier
authors.forename: Roy M
authors.initials: RM
authors.lastname: Robins-Browne
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D044082:Citrobacter rodentium / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity*; D004269:DNA, Bacterial / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; C072722:RegA protein, Bacteria