title: Stereoselective synthesis of oxazino[4,3-a]indoles employing the oxa-Pictet-Spengler reaction of indoles bearing N-tethered vinylogous carbonate.
abstract: A one-pot, sequential 2,3-bis-functionalization of indoles bearing N-tethered vinylogous carbonates employing an intramolecular oxa-Pictet-Spengler reaction followed by electrophilic substitution is developed for the stereoselective synthesis of oxazino[4,3-a]indoles.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, Tamil Nadu, India. sjgharpure@iitm.ac.in
authors.forename: Santosh J
authors.initials: SJ
authors.lastname: Gharpure
authors.forename: A M
authors.initials: AM
authors.lastname: Sathiyanarayanan
mesh_terms: D002254:Carbonates / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D002254:Carbonates; D007211:Indoles; D009584:Nitrogen