title: AMPK-dependent phosphorylation of ULK1 induces autophagy.
abstract: AMP-activated protein kinase (AMPK) is a highly conserved cellular energy sensor that plays a central role in metabolic homeostasis. A recent study in Science (Egan et al., 2011) identifies ULK1 as a substrate for AMPK phosphorylation, a modification required for selective autophagy of mitochondria and cell survival during starvation.
authors.affiliation: Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Mantong
authors.initials: M
authors.lastname: Zhao
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Klionsky