title: [Plant-specific type III polyketide synthase superfamily: gene structure, function and metabolites].
abstract: Plant-specific type III polyketide synthase (PKS) produces a variety of plant secondary metabolites with notable structural diversity and biological activity. So far 14 plant-specific type III PKS have been identified according to their enzymatic products, and the corresponding genes have been cloned and characterized. The differences among the various PKS are mainly in their substrate specificities, the number of their condensation reactions, and the type of ring closure of their products. However, numerous studies have revealed the common features among the plant-specific type III PKS, which include sequence homology, similar gene structure, conserved amino acid residues in the reaction center, enzymatic characteristics and reaction mechanism. We briefly reviewed 14 plant-specific type III PKS to better understand genetic and metabolic engineering of plant-specific type III PKS.
authors.affiliation: Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture China, Beijing University of Agriculture, Beijing 102206, China. lqma@bac.edu.cn
authors.forename: Lanqing
authors.initials: L
authors.lastname: Ma
authors.forename: Guanglu
authors.initials: G
authors.lastname: Shi
authors.forename: Hechun
authors.initials: H
authors.lastname: Ye
authors.forename: Benye
authors.initials: B
authors.lastname: Liu
authors.forename: Younian
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000217:Acyltransferases / Q000235:genetics* / Q000378:metabolism* / Q000502:physiology; D017343:Genes, Plant; D005818:Genetic Engineering; D060847:Metabolic Engineering; D010944:Plants / Q000201:enzymology* / Q000235:genetics; D013379:Substrate Specificity
chemical_list: D000217:Acyltransferases; C020141:flavanone synthetase