title: Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1.
authors.affiliation: Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, Australia.
authors.forename: Jerome
authors.initials: J
authors.lastname: Wielens
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Headey
authors.forename: John J
authors.initials: JJ
authors.lastname: Deadman
authors.forename: David I
authors.initials: DI
authors.lastname: Rhodes
authors.forename: Giang T
authors.initials: GT
authors.lastname: Le
authors.forename: Michael W
authors.initials: MW
authors.lastname: Parker
authors.forename: David K
authors.initials: DK
authors.lastname: Chalmers
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Scanlon
mesh_terms: D001665:Binding Sites; D002384:Catalysis; D019427:HIV Integrase / Q000187:drug effects* / Q000378:metabolism; D006860:Hydrogen Bonding; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular
chemical_list: D008024:Ligands; D019427:HIV Integrase; C514801:p31 integrase protein, Human immunodeficiency virus 1