title: [Hypothyroidism, dilated cardiomyopathy and nephrotic syndrome during pregnancy].
abstract: Hypothyroidism during pregnancy is infrequent, but its presence is associated with maternal and fetal complications. We present the case of a young pregnant woman with no previous history of cardiovascular disease, who consulted for orthopnea, chest pain and edema in both legs. Laboratory tests demonstrated a hypothyroid condition and a nephrotic syndrome with renal failure. The echo-Doppler exam showed a four chamber dilatation with systolic dysfunction. Treatment with intravenous levothyroxine improved her medical condition. We analyze the effects of thyroid hormone on the heart and vascular system and discuss the pathophysiologic mechanisms of heart failure during pregnancy.
authors.affiliation: División Cardiología, Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires. aksaad@arnet.com.ar
authors.forename: Ariel K
authors.initials: AK
authors.lastname: Saad
authors.forename: Guillermo
authors.initials: G
authors.lastname: Lopez Soutric
authors.forename: Yael
authors.initials: Y
authors.lastname: Nowicky
authors.forename: Jorge
authors.initials: J
authors.lastname: Lerman
authors.forename: Manuel
authors.initials: M
authors.lastname: Vazquez Blanco
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D009404:Nephrotic Syndrome / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D013963:Thyroid Hormones / Q000502:physiology
chemical_list: D013963:Thyroid Hormones