title: Adiponectin receptor signaling: a new layer to the current model.
abstract: Adiponectin and its receptors, AdipoR1 and AdipoR2, regulate glucose and fatty acid metabolism partly via activation of AMP-activated protein kinase (AMPK). Recent work in Nature Medicine (Holland et al., 2011) suggests that adiponectin stimulates ceramidase activity through AdipoR1 and AdipoR2, an activity potentially involved in promoting cell survival.
authors.affiliation: Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. kadowaki-3im@h.u-tokyo.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Kadowaki
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Yamauchi