title: [Clinical and morphological parallels of various degrees of chronic arterial insufficiency of lower limbs (review of the literature)].
abstract: The article deals with the main clinical and instrumental methods of determining severity of chronic arterial insufficiency of the lower extremities, showing possibilities of morphological studies for an accurate diagnosis of the ischaemia degree. Also determined are promising trends of studying the hypoxia-inducible factor (HIF) and vascular endothelial growth factor (VEGF) in assessment of ischaemic impairments of lower-extremities tissue.
authors.forename: M R
authors.initials: MR
authors.lastname: Kuznetsov
authors.forename: V P
authors.initials: VP
authors.lastname: Chernikov
authors.forename: S A
authors.initials: SA
authors.lastname: Tepliakov
authors.forename: A V
authors.initials: AV
authors.lastname: Sizarev
authors.forename: B V
authors.initials: BV
authors.lastname: Tugdumov
authors.forename: M G
authors.initials: MG
authors.lastname: Gabieva
authors.forename: N S
authors.initials: NS
authors.lastname: Dzhalilova
mesh_terms: D001157:Arterial Occlusive Diseases / Q000097:blood / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood*; D002908:Chronic Disease; D018450:Disease Progression; D005080:Exercise Test; D006801:Humans; D051793:Hypoxia-Inducible Factor 1 / Q000097:blood; D007866:Leg / Q000098:blood supply*; D011379:Prognosis; D012720:Severity of Illness Index; D042461:Vascular Endothelial Growth Factor A / Q000097:blood
chemical_list: D015415:Biomarkers; D051793:Hypoxia-Inducible Factor 1; D042461:Vascular Endothelial Growth Factor A