title: Compilation of secondary metabolites from Bidens pilosa L.
abstract: Bidens pilosa L. is a cosmopolitan annual herb, known for its traditional use in treating various diseases and thus much studied for the biological activity of its extracts, fractions and isolated compounds. Polyacetylenes and flavonoids, typical metabolite classes in the Bidens genus, predominate in the phytochemistry of B. pilosa. These classes of compounds have great taxonomic significance. In the Asteraceae family, the acetylene moiety is widely distributed in the Heliantheae tribe and some representatives, such as 1-phenylhepta-1,3,5-triyne, are noted for their biological activity and strong long-wave UV radiation absorbance. The flavonoids, specifically aurones and chalcones, have been reported as good sub-tribal level markers. Natural products from several other classes have also been isolated from different parts of B. pilosa. This review summarizes the available information on the 198 natural products isolated to date from B. pilosa.
authors.affiliation: Laboratório de Tecnologia Farmacêutica, Universidade Federal da Paraíba, Cx. Postal 5009, 58051-970 João Pessoa, PB, Brazil. falimasilva@hotmail.com
authors.forename: Fabiana Lima
authors.initials: FL
authors.lastname: Silva
authors.forename: Dominique Corinne Hermine
authors.initials: DC
authors.lastname: Fischer
authors.forename: Josean Fechine
authors.initials: JF
authors.lastname: Tavares
authors.forename: Marcelo Sobral
authors.initials: MS
authors.lastname: Silva
authors.forename: Petronio Filgueiras
authors.initials: PF
authors.lastname: de Athayde-Filho
authors.forename: Jose Maria
authors.initials: JM
authors.lastname: Barbosa-Filho
mesh_terms: D031176:Bidens / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry / Q000378:metabolism; D005419:Flavonoids / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008519:Medicine, Traditional; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000378:metabolism* / Q000627:therapeutic use; D053279:Polyynes / Q000737:chemistry / Q000378:metabolism*
chemical_list: D001688:Biological Products; D005419:Flavonoids; D010936:Plant Extracts; D053279:Polyynes