title: Collapsing glomerulopathy in a girl with systemic lupus erythematosus.
abstract: Collapsing glomerulopathy has increasingly been recognised in patients with conditions other than HIV. The non-HIV form of collapsing glomerulopathy generally shows little response to standard therapies. We describe a 12-year-old girl with a pre-existing diagnosis of systemic lupus erythematosus presenting with renal failure. A renal biopsy gave the histological diagnosis of collapsing glomerulopathy with evidence of "full-house" immunostaining. We propose collapsing glomerulopathy in her case, as no other cause was found was secondary to systemic lupus erythematosus. The immunophenotype of her podocytes suggested a partial de-differentiation that might have been important in her partial response to immunosuppression.
authors.affiliation: Histopathology Department, St. Thomas' Hospital, Guy's and St Thomas' NHS Trust, London, UK.
authors.forename: M Fahim
authors.initials: MF
authors.lastname: Tungekar
authors.forename: Simon
authors.initials: S
authors.lastname: Waller
authors.forename: Joanna C
authors.initials: JC
authors.lastname: Clothier
mesh_terms: D002648:Child; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000503:physiopathology