title: Two cases of drug-induced orbital inflammatory disease.
abstract: Orbital inflammatory disease (OID) includes all inflammatory processes affecting the orbit. Although several aetiologies are recognised, a cause may not be elucidated. We describe 2 cases in which drugs (hyaluronidase and zoledronic acid) were the cause of OID. In patients with a clinical picture of OID simulating an orbital cellulitis, the recent drug history should be considered as a possible aetiology, and treatment with steroids with or without a biopsy should be considered after an infection has been excluded.
authors.affiliation: Instituto Clinico de Oftalmologia, Hospital Clinic, Barcelona, Spain. san.ortiz@gmail.com
authors.forename: Santiago
authors.initials: S
authors.lastname: Ortiz-Perez
authors.forename: Estrella
authors.initials: E
authors.lastname: Fernandez
authors.forename: Juan Jose
authors.initials: JJ
authors.lastname: Molina
authors.forename: Bernardo
authors.initials: B
authors.lastname: Sanchez-Dalmau
authors.forename: Manuel
authors.initials: M
authors.lastname: Navarro
authors.forename: Xavier
authors.initials: X
authors.lastname: Corretger
authors.forename: Jane M
authors.initials: JM
authors.lastname: Olver
mesh_terms: D000368:Aged; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D002387:Cataract Extraction; D002481:Cellulitis / Q000175:diagnosis; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000009:adverse effects*; D007093:Imidazoles / Q000009:adverse effects*; D007249:Inflammation / Q000139:chemically induced / Q000175:diagnosis; D009916:Orbital Diseases / Q000139:chemically induced* / Q000175:diagnosis; D010145:Paget Disease, Extramammary / Q000188:drug therapy*; D000077211:Zoledronic Acid
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D000077211:Zoledronic Acid; D006821:Hyaluronoglucosaminidase