title: Recent developments in drug-eluting stents.
abstract: Percutaneous coronary intervention (PCI) is an important treatment approach in the management of symptomatic coronary artery disease (CAD). A significant development in PCI in the mid 1970s was balloon angioplasty, followed by bare-metal stents a decade later, and now, the widespread use of drug-eluting stents (DES). While PCI has conferred remarkable benefit to millions of CAD patients, restenosis, and late stent thrombosis associated with DES remain problematic, and improvements are keenly sought. This article reviews recent developments in DES.
authors.affiliation: Centre for Vascular Research, University of New South Wales, Sydney, Australia.
authors.forename: Yue
authors.initials: Y
authors.lastname: Li
authors.forename: Ravinay
authors.initials: R
authors.lastname: Bhindi
authors.forename: Levon M
authors.initials: LM
authors.lastname: Khachigian
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis; D054855:Drug-Eluting Stents / Q000009:adverse effects; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage; D011108:Polymers; D020123:Sirolimus / Q000008:administration & dosage; D013927:Thrombosis; D016896:Treatment Outcome
chemical_list: D011108:Polymers; D017239:Paclitaxel; D020123:Sirolimus