title: Metabolic syndrome features presenting in early childhood in Alström syndrome: a case report.
abstract: Alström syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, early-onset obesity, and non-insulin-dependent diabetes mellitus. Affected individuals have normal birth weight, but growth deceleration starts at about 8-10 years of age. In patients with the disorder linked to chromosome 2, the increase in body mass index is very high in childhood and continues high thereafter. In this paper, we report a patient who had the proposed diagnostic criteria for Alström syndrome associated with metabolic syndrome starting at age 7, a relatively early age.
authors.affiliation: Department of Pediatric Endocrinology, GATA Medical Faculty, İstanbul, Turkey. ozpirgon@hotmail.com
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Pirgon
authors.forename: Mehmet Emre
authors.initials: ME
authors.lastname: Atabek
authors.forename: Ilhan Asya
authors.initials: IA
authors.lastname: Tanju
mesh_terms: D056769:Alstrom Syndrome / Q000150:complications* / Q000235:genetics; D002648:Child; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology