title: Does a supplementary preoperative breast MRI in patients with invasive lobular breast cancer change primary and secondary surgical interventions?
abstract: BACKGROUND
  We evaluated whether a supplementary preoperative breast MRI in patients with invasive lobular breast cancer (ILC) has changed number and methods of primary and number of secondary surgical interventions.
  
  
  METHODS
  This was a retrospective controlled single-center analysis of 178 ILC patients. The 2 study groups consisted of 92 patients with breast MRI (MRI group) and of 86 patients without breast MRI (non-MRI group). We investigated the primary and final surgical procedures and factors that influenced the number of secondary surgical interventions.
  
  
  RESULTS
  A total of 40 primary mastectomies (38%) have been performed in the MRI group, compared with 27 (30%) in the non-MRI group (P = .119).There have been more bilateral surgical interventions in the MRI group (14 vs 3 patients; P = .002). The 2 groups did not differ with respect to secondary surgery rates (P = .429). The MRI and non-MRI group were significantly different with respect to age and breast density (P = .003 and P = .002). Yet, both variables seemed not to influence secondary surgery rates (P = .516 and P = .788, respectively).
  
  
  CONCLUSIONS
  The implementation of preoperative breast MRI tended to result in more primary mastectomies and bilateral surgeries and did not seem to decrease the secondary surgery rate.
authors.affiliation: University Breast Center Heidelberg, Heidelberg, Germany. joerg.heil@med.uni-heidelberg.de
authors.forename: Joerg
authors.initials: J
authors.lastname: Heil
authors.forename: Anne
authors.initials: A
authors.lastname: Bühler
authors.forename: Michael
authors.initials: M
authors.lastname: Golatta
authors.forename: Joachim
authors.initials: J
authors.lastname: Rom
authors.forename: Aba
authors.initials: A
authors.lastname: Harcos
authors.forename: Anne
authors.initials: A
authors.lastname: Schipp
authors.forename: Geraldine
authors.initials: G
authors.lastname: Rauch
authors.forename: Hans
authors.initials: H
authors.lastname: Junkermann
authors.forename: Christof
authors.initials: C
authors.lastname: Sohn
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000175:diagnosis / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011300:Preoperative Care; D012086:Reoperation; D015996:Survival Rate; D016896:Treatment Outcome