title: Atherosclerotic renal artery stenosis: an update on diagnosis and management.
abstract: Atherosclerotic renal artery stenosis (ARAS) is a progressive disease and it is usually associated with hypertension as well as with chronic kidney and cardiovascular disease. Although the anatomical lesions are relatively easy to depict, there is need to identify diagnostic methods to establish the functional significance of the stenosis and predict the response to revascularization. Over the last years, renal revascularization appears to be increasingly performed in patients with ARAS. However, controversy abounds as so far prospective, randomised trials did not document any benefit of revascularization with or without stenting plus optimal medical treatment over optimal medical treatment alone. In this review, we discuss the current data in the field of diagnosis and management of patients with ARAS.
authors.affiliation: Department of Nephrology, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Greece.
authors.forename: Eirini
authors.initials: E
authors.lastname: Stavrinou
authors.forename: Charalambos
authors.initials: C
authors.lastname: Koumaras
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Gossios
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Tziomalos
authors.forename: Vasilios G
authors.initials: VG
authors.lastname: Athyros
authors.forename: Asterios
authors.initials: A
authors.lastname: Karagiannis
mesh_terms: D050197:Atherosclerosis / Q000150:complications*; D002318:Cardiovascular Diseases / Q000209:etiology; D018450:Disease Progression; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007674:Kidney Diseases / Q000209:etiology; D016032:Randomized Controlled Trials as Topic; D012078:Renal Artery Obstruction / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome