title: Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice.
abstract: The unresponsiveness to LPS detected in C57BL/10Cr mice is inherited as a recessive trait and is determined by an autosomal gene linked to theMup-1 locus on chromosome 4. Since no complementation for LPS responsiveness was observed in F(1) hybrid mice between C3H/HeJ and C57BL/10Cr, we conclude that C57BL/10Cr mice carry a defective allele at the sameLps locus, previously identified by the mutation detected in the C3H/HeJ strain.
authors.affiliation: Basel Institute for Immunology, Grenzacherstrasse 487, Postfach, 4005, Basel 5, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Coutinho
authors.forename: T
authors.initials: T
authors.lastname: Meo