title: Cutaneous myxosarcoma with pulmonary metastases in a dog.
abstract: The pathological findings in a 13-year-old dog with cutaneous myxosarcoma with pulmonary metastases are described. Grossly, there was a large subcutaneous mass in the right scapular region, a smaller nodule in the caudal abdominal region and a fibrotic mass at a fracture site in the right hindlimb. Radiographic examination revealed several pulmonary nodules. Microscopical evaluation revealed a myxosarcoma characterized by the proliferation of spindle to stellate cells with multiple prominent nucleoli and vascular invasion. The neoplastic cells were haphazardly arranged in a mucopolysaccharide matrix. Immunohistochemically, the neoplastic cells expressed vimentin, but not cytokeratin or glial fibrillary acidic protein. There was restricted expression of desmin, smooth muscle actin and S-100 protein.
authors.affiliation: Section of Veterinary Pathology, Department of Basic Veterinary Sciences University of Helsinki, Finland. sheadley@smu.ky
authors.forename: S A
authors.initials: SA
authors.lastname: Headley
authors.forename: A C
authors.initials: AC
authors.lastname: Faria Dos Reis
authors.forename: A P Frederico R L
authors.initials: AP
authors.lastname: Bracarense
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary*; D009236:Myxosarcoma / Q000473:pathology / Q000662:veterinary*; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*