title: Nonbreast-fed HIV-1-exposed Burkinabe infants have low energy intake between 6 and 11 months of age despite free access to infant food aid.
abstract: In a WHO-coordinated, mother-to-child HIV transmission (MTCT) prevention trial in Burkina Faso, HIV-1-infected mothers were advised to either stop breast-feeding by 6 mo or totally avoid it. Participants were provided with cereal-based, infant fortified mix (IFM) from 6 to 12 mo postpartum along with infant feeding counseling. Our objective was to describe nonbreast-fed infants' food consumption and adequacy of nutrient intake. A 1-d weighed food record and one 24-h dietary recall were performed in 68 nonbreast-fed, non-HIV-infected 6- to 11-mo-old infants. Mean food energy density and feeding frequency were satisfactory in 6-8 mo olds [0.8 ± 0.2 kcal/g (3.3 ± 0.9 kJ/g) and 7.2 ± 1.6 times/d] and in 9-11 mo olds [0.9 ± 0.2 kcal/g (3.6 ± 0.8 kJ/g) and 7.7 ± 2.1 times/d]. Median energy intake was 523 kcal [range: 82-1053 (2187 kJ, range: 345-4401)] in 6-8- and 811 kcal [range: 34-1543 (3392 kJ, range: 144-6452)] in 9-11-mo-old infants, respectively. Approximately 75% of their energy intake was provided by subsidized foods (milk that mothers obtained from support networks and IFM). One-half of the infants had intakes < 80 kcal/kg (<334 kJ/kg) on the day of the survey, mainly because IFM and milk were consumed in amounts that were too low. Thus, coverage of energy needs required a diet with sufficient amounts of both IFM and milk in these vulnerable infants. These findings argue for the development of adequate, sustainable infant fortified foods and their rapid integration into MTCT prevention services. They also lend support to the recent revision of WHO infant feeding guidance for future MTCT prevention programming that recommends breast-feeding up to 12 mo postpartum (under cover of antiretroviral prophylaxis) as the safest feeding option for infants of HIV-infected mothers.
authors.affiliation: UMI233, IRD/UM1, Montpellier 34394, France. cecile.cames@ird.fr
authors.forename: Cécile
authors.initials: C
authors.lastname: Cames
authors.forename: Fanny
authors.initials: F
authors.lastname: Cassard
authors.forename: Amandine
authors.initials: A
authors.lastname: Cournil
authors.forename: Claire
authors.initials: C
authors.lastname: Mouquet-Rivier
authors.forename: Kossiwavi
authors.initials: K
authors.lastname: Ayassou
authors.forename: Nicolas
authors.initials: N
authors.lastname: Meda
authors.forename: Kirsten
authors.initials: K
authors.lastname: Bork
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology / Q000517:prevention & control*; D002657:Child Development; D002149:Energy Intake; D015497:HIV-1; D006801:Humans; D007223:Infant; D041943:Infant Formula; D007227:Infant Nutritional Physiological Phenomena; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*