title: Synthesis and catalytic activity of histidine-based NHC ruthenium complexes.
abstract: Main-chain C,N-protected histidine has been successfully alkylated at both side-chain nitrogens. The corresponding histidinium salt was metallated with ruthenium(II) by a transmetalation procedure, thus providing histidine-derived NHC ruthenium complexes. These bio-inspired complexes show appreciable activity in the catalytic transfer hydrogenation of ketones.
authors.affiliation: School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Angèle
authors.initials: A
authors.lastname: Monney
authors.forename: Galmari
authors.initials: G
authors.lastname: Venkatachalam
authors.forename: Martin
authors.initials: M
authors.lastname: Albrecht
mesh_terms: D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006639:Histidine / Q000737:chemistry*; D006865:Hydrogenation; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008968:Molecular Conformation; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D006571:Heterocyclic Compounds; C030011:carbene; D006639:Histidine; D012428:Ruthenium; D008697:Methane