title: Continued emergence and changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus, United Kingdom, winter 2010/11.
abstract: During the winter period 2010/11 27 epidemiologically unlinked, confirmed cases of oseltamivir-resistant influenza A(H1N1)2009 virus infection have been detected in multiple, geographically dispersed settings. Three of these cases were in community settings, with no known exposure to oseltamivir. This suggests possible onward transmission of resistant strains and could be an indication of a possibility of changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus.
authors.affiliation: Health Protection Agency, Microbiology Services Colindale, London, United Kingdom. angie.lackenby@hpa.org.uk
authors.forename: A
authors.initials: A
authors.lastname: Lackenby
authors.forename: J
authors.initials: J
authors.lastname: Moran Gilad
authors.forename: R
authors.initials: R
authors.lastname: Pebody
authors.forename: S
authors.initials: S
authors.lastname: Miah
authors.forename: L
authors.initials: L
authors.lastname: Calatayud
authors.forename: S
authors.initials: S
authors.lastname: Bolotin
authors.forename: I
authors.initials: I
authors.lastname: Vipond
authors.forename: P
authors.initials: P
authors.lastname: Muir
authors.forename: M
authors.initials: M
authors.lastname: Guiver
authors.forename: J
authors.initials: J
authors.lastname: McMenamin
authors.forename: A
authors.initials: A
authors.lastname: Reynolds
authors.forename: C
authors.initials: C
authors.lastname: Moore
authors.forename: R
authors.initials: R
authors.lastname: Gunson
authors.forename: C
authors.initials: C
authors.lastname: Thompson
authors.forename: M
authors.initials: M
authors.lastname: Galiano
authors.forename: A
authors.initials: A
authors.lastname: Bermingham
authors.forename: J
authors.initials: J
authors.lastname: Ellis
authors.forename: M
authors.initials: M
authors.lastname: Zambon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D024882:Drug Resistance, Viral; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D007251:Influenza, Human / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009439:Neuraminidase / Q000235:genetics; D053139:Oseltamivir / Q000627:therapeutic use*; D058873:Pandemics; D020641:Polymorphism, Single Nucleotide; D011159:Population Surveillance; D012621:Seasons; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir; D009439:Neuraminidase