title: Aggressive management of tibial osteomyelitis shows good functional outcomes.
abstract: BACKGROUND
  Severe open tibial fractures can be successfully treated acutely with a combined orthopedic and plastic surgery approach, but a proportion will go on to develop chronic osteomyelitis. For the past 6 years, an aggressive approach of bone and soft tissue debridement followed by skeletal reconstruction and vascularized tissue transfer has been pursued by the orthopedic and plastic surgery teams at Liverpool Hospital. We present the results of our patient series.
  
  
  METHODS
  All patients treated for chronic osteomyelitis by combined skeletal stabilization, debridement, and flap coverage between January 2000 and July 2006 were included. Clinical record review was combined with patient interviews and questionnaires. Outcome measures included fracture union, stable soft tissue coverage, freedom from infection, mobility, return to work/sport, and pain.
  
  
  RESULTS
  Twelve patients were followed up after a mean of 4.2 years. Patients had undergone a mean of 8.4 procedures prior to treatment, and a mean of 2.5 procedures as part of their treatment. We achieved fracture union, stable soft tissue coverage, and eradicated infection in all patients. All patients were walking, 10 unaided, and 80% had returned to work. All but one patient involved in sport at the time of injury had returned to sport. Two patients had mild pain when walking long distances only.
  
  
  CONCLUSIONS
  Skeletal stabilization, debridement, and flap coverage is costly and complex surgery. However, in our series, these interventions resulted in eradication of infection and good clinical outcomes in most cases, providing an alternative to both amputation and long-term antibiotic therapy.
authors.affiliation: Departments of Plastic and Reconstructive Surgery and Orthopaedic Surgery, Liverpool Hospital and the South Western Clinical School, University of New South Wales, Sydney Australia.
authors.forename: Raewyn
authors.initials: R
authors.lastname: Campbell
authors.forename: M G
authors.initials: MG
authors.lastname: Berry
authors.forename: Anand
authors.initials: A
authors.lastname: Deva
authors.forename: Ian A
authors.initials: IA
authors.lastname: Harris