title: [Regulatory peptides influence on hypoxia induced tooth germ pathology of new born albino rats].
abstract: Intrauterine hypoxia decreased the nucleolar organizator quantity in enameloblasts of newborn albino rats tooth germ. Influence the leu-encepgalin synthetic analog dalargin and non-opiate synthetic leu-encephalin on newborn rats from 2 to 6 day abolished the intrauterine hypoxia affect. The main mechanism of peptide antioxidant effect may be NO system stimulation.
authors.forename: O I
authors.initials: OI
authors.lastname: Arsenina
authors.forename: S V
authors.initials: SV
authors.lastname: Proskokova
authors.forename: E N
authors.initials: EN
authors.lastname: Sazonova
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D003743:Dental Enamel / Q000002:abnormalities / Q000187:drug effects* / Q000378:metabolism; D016308:Enkephalin, Leucine-2-Alanine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D005311:Fetal Hypoxia / Q000150:complications* / Q000188:drug therapy*; D009569:Nitric Oxide / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014083:Tooth Germ / Q000002:abnormalities / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D009569:Nitric Oxide; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-