title: Febrile ulceronecrotic Mucha-Habermann disease in adult patient successfully treated with systemic corticosteroid.
abstract: The Febrile Ulceronecrotic Mucha-Habermann (FUMHD) disease is a rare variant of pityriasis lichenoides et varioliformis acuta (PLEVA). Its etiology still remains unknown and it is characterized by a sudden onset of ulceronecrotic skin lesions associated with systemic symptoms. It is reported here the case of a male patient with a sudden and acute evolution of macules and papules, ulceronecrotic and vesicle-bullous lesions associated with systemic symptoms. The patient was treated with prednisone 0.5 mg/kg/day with a dramatic response. The FUMHD is a severe variant of PLEVA and its diagnosis is clinical and histopathological. Many treatments such as methotrexate, corticosteroids and PUVA have been described. However, none of them has been settled.
authors.affiliation: Lauro de Souza Lima Institute , Bauru, SP, Brasil. priwolf@gmail.com
authors.forename: Priscila Wolf
authors.initials: PW
authors.lastname: Nassif
authors.forename: Deise Aparecida Santos
authors.initials: DA
authors.lastname: Godoy
authors.forename: Sadamitsu
authors.initials: S
authors.lastname: Nakandakari
authors.forename: Cinthia Janine Meira
authors.initials: CJ
authors.lastname: Alves
authors.forename: Cleverson Teixeira
authors.initials: CT
authors.lastname: Soares
mesh_terms: D005938:Glucocorticoids / Q000627:therapeutic use*; D006561:Herpes Simplex / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017514:Pityriasis Lichenoides / Q000188:drug therapy* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011241:Prednisone