title: Efficient monophosphorus ligands for palladium-catalyzed Miyaura borylation.
abstract: In combination with the Bedford Pd precursor, the new biaryl monophosphorus ligand 5 was efficient for palladium-catalyzed Miyaura borylation of sterically hindered aryl bromides at low catalyst loadings.
authors.affiliation: Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut 06877, United States. wenjun.tang@boehringer-ingelheim.com
authors.forename: Wenjun
authors.initials: W
authors.lastname: Tang
authors.forename: Santosh
authors.initials: S
authors.lastname: Keshipeddy
authors.forename: Yongda
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xudong
authors.initials: X
authors.lastname: Wei
authors.forename: Jolaine
authors.initials: J
authors.lastname: Savoie
authors.forename: Nitinchandra D
authors.initials: ND
authors.lastname: Patel
authors.forename: Nathan K
authors.initials: NK
authors.lastname: Yee
authors.forename: Chris H
authors.initials: CH
authors.lastname: Senanayake
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D006842:Hydrocarbons, Brominated; D008024:Ligands; D009943:Organophosphorus Compounds; D010165:Palladium