title: A new way to reduce flow disturbance in endovascular stents: a numerical study.
abstract: Traditional commercial stents are made of wires with square or semi-circular cross-sections that lead to flow disturbance, which plays an important role in the initiation and progression of restenosis. A new stent with streamlined cross-sectional wires was proposed and researched numerically for its hemodynamic performance. Simplified models of stents with square, semi-circular, or streamlined cross-sectional wires were constructed numerically. Blood flows in the three models were simulated using computational fluid dynamics methods, and compared in terms of flow pattern, wall shear stress (WSS), and oscillating shear index (OSI). The results showed that when compared with the two traditional stents, the new stent with streamlined cross-sectional wires induced almost no flow disturbance, significantly enhanced WSS, and reduced the value of OSI within the stent. The present preliminary study indicates that the optimization of the cross-sectional shape of stent wires ought to be considered in the structural design for endovascular stents.
authors.affiliation: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
authors.forename: Zengsheng
authors.initials: Z
authors.lastname: Chen
authors.forename: Yubo
authors.initials: Y
authors.lastname: Fan
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Deng
authors.forename: Zaipin
authors.initials: Z
authors.lastname: Xu
mesh_terms: D003198:Computer Simulation; D006439:Hemodynamics; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D015607:Stents; D013314:Stress, Mechanical