title: Blood, bugs, and motion - what do we really know in regard to total joint arthroplasty?
abstract: In total joint arthroplasty, it is often necessary to formulate decisions that are not clearly evidence-based. This review presents some current controversial topics in total joint arthroplasty, including preoperative autologous blood donation versus erythropoietin (EPO) usage, preoperative screening and treatment for methicillin resistant Staphylococcus aureus (MRSA), and the use of continuous passive motion (CPM) following total knee arthroplasty, providing an evidence-based guide for the treating orthopaedic surgeon. Our review shows that preoperative autologous blood donation is over utilized, with EPO being under utilized. Surgeons are encouraged to develop patient-specific strategies, which have been shown to decrease transfusion rates, reduce wasted autologous blood, and increase EPO use. Definitive conclusions regarding MRSA screening for orthopaedic patients cannot be drawn; but due to the significant cost and morbidity associated with a postoperative MRSA infection, we believe a screen and treat protocol should be considered for all patients being admitted to the hospital for elective or emergent surgery. Short-term (3 to 5 days) inpatient use of CPM is recommended at this time. It is low-cost, has minimal risk, and may be a factor in decreasing the length of stay, potentially leading to significant cost savings. However, no long-term benefits of CPM use have been established.
authors.affiliation: Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY, USA.
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Glassner
authors.forename: James D
authors.initials: JD
authors.lastname: Slover
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Bosco
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Zuckerman
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D001782:Blood Donors; D004921:Erythropoietin / Q000008:administration & dosage; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D055624:Methicillin-Resistant Staphylococcus aureus; D015915:Motion Therapy, Continuous Passive; D016059:Range of Motion, Articular
chemical_list: D004921:Erythropoietin