title: CarD: a new RNA polymerase modulator in mycobacteria.
abstract: Mycobacteria CarD is an essential RNAP binding protein that regulates many transcripts including rRNA. This article will review our present state of knowledge regarding CarD and compare the known functions of CarD with other RNAP binding proteins in E. coli, emphasizing how this information can guide future investigations.
authors.affiliation: Department of Molecular Microbiology, Washington University, St. Louis, MO, USA. stallings@borcim.wustl.edu
authors.forename: Christina L
authors.initials: CL
authors.lastname: Stallings
authors.forename: Michael S
authors.initials: MS
authors.lastname: Glickman
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D004261:DNA Replication; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D005816:Genetic Complementation Test; D008957:Models, Genetic; D009154:Mutation; D011485:Protein Binding; D012335:RNA, Ribosomal / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D029968:Escherichia coli Proteins; D012335:RNA, Ribosomal; D014157:Transcription Factors; C090751:dksA protein, E coli; C072103:transcription repair coupling factor protein, Bacteria; D012321:DNA-Directed RNA Polymerases