title: Designing drugs to avoid toxicity.
authors.affiliation: Central Chemistry Team Lead, Merck Research Laboratories, Boston, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
authors.forename: Graham F
authors.initials: GF
authors.lastname: Smith
mesh_terms: D000818:Animals; D054715:Cardiotoxins / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D002319:Cardiovascular System / Q000187:drug effects; D015195:Drug Design; D064420:Drug-Related Side Effects and Adverse Reactions / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000187:drug effects; D008659:Metabolic Diseases / Q000139:chemically induced; D009153:Mutagens / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D055668:Photochemical Processes; D014466:Ultraviolet Rays
chemical_list: D054715:Cardiotoxins; D009153:Mutagens; D004364:Pharmaceutical Preparations; D010743:Phospholipids