title: Surgical treatment of intracardiac leiomyomatosis.
abstract: OBJECTIVE
  Confusion exists regarding surgical algorithms for treating intracardiac leiomyomatosis. This report outlines the surgical management and outcomes of patients with intracardiac leiomyomatosis.
  
  
  METHODS
  Sixteen cases of intracardiac leiomyomatosis surgically treated in Anzhen Hospital from February 1995 to July 2010 were reviewed retrospectively. According to relative size and location of intracardiac leiomyoma maximum diameter relative to diameter of inferior vena cava, the 16 cases were classified as type A, B, C, or D.
  
  
  RESULTS
  Of the 16 cases in this series, there were 7 type A, 2 type B, 3 type C, and 4 type D. No patients died during surgery. Mean follow-up was 90 ± 57.1 months (cumulative, 120.2 patient-years; range, 2-190 months). One patient died of recurrence 5 months after the surgery because of incomplete resection. Another patient with type D also died of recurrence 2 years after the primary procedure. A patient with type D died suddenly 10 years after the primary procedure. The 5-year and 10-year survivals calculated by the Kaplan-Meier method were 87.1% ± 8.6% and 72.5% ± 15%. Of the 13 surviving patients, 11 were in New York Heart Association functional class I and 2 were in functional class II.
  
  
  CONCLUSIONS
  Surgical treatment of intracardiac leiomyomatosis can result in satisfactory midterm to long-term survival and satisfactory heart function. Multiple surgical strategies should be tailored to the anatomic characteristics of the intracardiac leiomyoma. Recurrence of intracardiac leiomyomatosis after the resection procedure may result in unfavorable late result.
authors.affiliation: Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China. ganhuili@hotmail.com
authors.forename: Hui-Li
authors.initials: HL
authors.lastname: Gan
authors.forename: Jian-Qun
authors.initials: JQ
authors.lastname: Zhang
authors.forename: Qi-Wen
authors.initials: QW
authors.lastname: Zhou
authors.forename: Qing-Yu
authors.initials: QY
authors.lastname: Kong
authors.forename: Shuang
authors.initials: S
authors.lastname: Zhao
authors.forename: Ping
authors.initials: P
authors.lastname: Bo
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000401:mortality; D002681:China; D005260:Female; D006338:Heart Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007044:Hysterectomy; D053208:Kaplan-Meier Estimate; D018231:Leiomyomatosis / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010052:Ovariectomy; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D058994:Salpingectomy; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D055815:Young Adult