title: Severe thrombocytopenia in aged rhesus macaques (Macaca mulatta) infected with simian varicella virus.
abstract: Simian varicella virus was diagnosed in 2 geriatric rhesus macaques (Macaca mulatta). The macaques presented with typical skin lesions as well as severe thrombocytopenia as a result of infection. Idiopathic thrombocytopenic purpura is a known complication of varicella zoster virus infection in humans; however, this condition has not been reported previously as a complication of SVV infection. This case report discusses the clinical presentation, pathology, and thrombocytopenia of the affected macaques.
authors.affiliation: Biologic Resources Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA. lhall@uic.edu
authors.forename: Lisa C
authors.initials: LC
authors.lastname: Halliday
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Fortman
mesh_terms: D000367:Age Factors; D018138:Alphaherpesvirinae; D000818:Animals; D005260:Female; D006566:Herpesviridae Infections / Q000097:blood / Q000150:complications / Q000662:veterinary*; D008253:Macaca mulatta / Q000097:blood / Q000821:virology*; D008297:Male; D008992:Monkey Diseases / Q000097:blood / Q000175:diagnosis / Q000821:virology*; D013921:Thrombocytopenia / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology