title: Thermodynamic stability of Hoogsteen and Watson-Crick base pairs in the presence of histone H3-mimicking peptide.
abstract: We found that Hoogsteen base pairs were stabilized by molecular crowding and a histone H3-mimicking peptide, which was not observed for Watson-Crick base pairs. Our findings demonstrate that the type of DNA base pair is critical for the interaction between DNA and histones.
authors.affiliation: Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan.
authors.forename: Smritimoy
authors.initials: S
authors.lastname: Pramanik
authors.forename: Kaori
authors.initials: K
authors.lastname: Nakamura
authors.forename: Kenji
authors.initials: K
authors.lastname: Usui
authors.forename: Shu-ichi
authors.initials: S
authors.lastname: Nakano
authors.forename: Sarika
authors.initials: S
authors.lastname: Saxena
authors.forename: Jun
authors.initials: J
authors.lastname: Matsui
authors.forename: Daisuke
authors.initials: D
authors.lastname: Miyoshi
authors.forename: Naoki
authors.initials: N
authors.lastname: Sugimoto
mesh_terms: D000595:Amino Acid Sequence; D020029:Base Pairing; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D006657:Histones / Q000737:chemistry* / Q000378:metabolism; D008969:Molecular Sequence Data; D009691:Nucleic Acid Denaturation; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism*; D011485:Protein Binding; D013816:Thermodynamics; D044366:Transition Temperature
chemical_list: D006657:Histones; D010455:Peptides; D004247:DNA