title: Dynamic combinatorial donor-acceptor catenanes in water: access to unconventional and unexpected structures.
abstract: We describe here the assembly of new types of donor-acceptor [2]catenanes from dynamic combinatorial libraries (DCL) in water. These new catenanes contain both the donor and acceptor components in at least one of the interlocked rings, thereby possessing unusual and unexpected DAAD or DADD stacking sequences of the π units in their structures. The efficiency of the catenane assembly process can be enhanced by manipulating the DCL equilibrium in a variety of ways: adding a guest, changing the building block stoichiometries, or increasing the library concentration or the ionic strength of the solvent. The formation of catenanes and their constitutions are found to be dependent on subtle differences in the geometry, dimension, and flexibility of the donor building blocks.
authors.affiliation: University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
authors.forename: Ho Yu
authors.initials: HY
authors.lastname: Au-Yeung
authors.forename: G Dan
authors.initials: GD
authors.lastname: Pantoş
authors.forename: Jeremy K M
authors.initials: JK
authors.lastname: Sanders
mesh_terms: D043863:Catenanes / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
chemical_list: D043863:Catenanes; D014867:Water