title: Subcutaneous fat necrosis in newborn-an unusual case and review of literature.
abstract: Subcutaneous fat necrosis (SCFN) of the newborn is an uncommon, self-limiting panniculitis mostly occurring within the first few weeks after birth. SCFN has been described mostly in term or post-term newborn infants in literature. We report a preterm infant developing extensive subcutaneous fat necrosis within the first week of life after significant perinatal hypoxic injury. The infant was conservatively managed for subcutaneous fat necrosis but developed hypercalcaemia and required prolonged medical treatment. Hypercalcaemia is a rare but serious complication of subcutaneous fat necrosis and needs prolonged follow-up. The etiopathogenesis of both subcutaneous fat necrosis in newborn and the resultant hypercalcaemia are poorly understood.
  
  
  CONCLUSIONS
  Significant subcutaneous fat necrosis can develop in both preterm and term infants, and preterm infants also develop significant complications including hypercalcaemia.
authors.affiliation: Clinical Research Fellow in Neonatology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust, Cambridge, CB2 0QQ, UK. subhabrata.mitra@addenbrookes.nhs.uk
authors.forename: Subhabrata
authors.initials: S
authors.lastname: Mitra
authors.forename: Jennifer
authors.initials: J
authors.lastname: Dove
authors.forename: Sateesh Kumar
authors.initials: SK
authors.lastname: Somisetty
mesh_terms: D005218:Fat Necrosis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006934:Hypercalcemia / Q000150:complications; D020925:Hypoxia-Ischemia, Brain / Q000150:complications; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008297:Male; D015434:Panniculitis / Q000150:complications / Q000175:diagnosis; D050151:Subcutaneous Fat / Q000473:pathology*