title: A rare case of peripartum endogenous bacterial endophthalmitis.
abstract: We describe the case of a healthy, pregnant female who developed endogenous endophthalmitis at the time of delivery, and discuss the possible mechanism of infection and the management of this case. A 26-year-old Asian woman presented with a 3-week history of visual deterioration and pain in the right eye. There was no history of ocular trauma or surgery. The ocular symptoms developed one day after vaginal delivery of a healthy baby. The pregnancy had been uncomplicated until premature rupture of membranes one week prior to delivery. Right visual acuity was light perception. There was marked right anterior chamber activity with a hypopyon and fibrin. A B-scan ultrasound showed dense vitritis. Examination of the left eye was normal. Blood tests and a chest X-ray were normal. A vitreous tap was performed and bacterial culture grew Sphingomonas paucimobilis. Intravitreal antibiotics were injected (amikacin 0.4 mg/0.1 ml and vancomycin 2.0 mg/0.1 ml) and the patient was treated with oral moxifloxacin and corticosteroids. Right visual acuity improved to 6/9. This case highlights the need for clinicians to have a high level of awareness of endogenous bacterial endophthalmitis (a rare, potentially sight-threatening condition) in any patient with a painful eye or visual deterioration in the peripartum period, particularly if associated with complications such as premature rupture of membranes or perineal laceration.
authors.affiliation: Moorfields Eye Hospital, London, UK.
authors.forename: Waheeda
authors.initials: W
authors.lastname: Rahman
authors.forename: Richard
authors.initials: R
authors.lastname: Hanson
authors.forename: Mark
authors.initials: M
authors.lastname: Westcott
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D036861:Delivery, Obstetric; D009877:Endophthalmitis / Q000150:complications / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy; D006801:Humans; D058449:Intravitreal Injections; D058725:Peripartum Period; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D020578:Sphingomonas; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology; D014792:Visual Acuity
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents