title: The probiotic Escherichia coli Nissle 1917 reduces pathogen invasion and modulates cytokine expression in Caco-2 cells infected with Crohn's disease-associated E. coli LF82.
abstract: Increased numbers of adherent invasive Escherichia coli (AIEC) have been found in Crohn's disease (CD) patients. In this report, we investigate the potential of the probiotic Escherichia coli Nissle 1917 (EcN) to reduce features associated with AIEC pathogenicity in an already established infection with AIEC reference strain LF82.
authors.affiliation: Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand. claudiahuebner17@hotmail.com
authors.forename: Claudia
authors.initials: C
authors.lastname: Huebner
authors.forename: Yaoyao
authors.initials: Y
authors.lastname: Ding
authors.forename: Ivonne
authors.initials: I
authors.lastname: Petermann
authors.forename: Christoph
authors.initials: C
authors.lastname: Knapp
authors.forename: Lynnette R
authors.initials: LR
authors.lastname: Ferguson
mesh_terms: D000898:Antibiosis; D018938:Caco-2 Cells; D003424:Crohn Disease / Q000382:microbiology*; D016207:Cytokines / Q000378:metabolism*; D004847:Epithelial Cells / Q000276:immunology / Q000382:microbiology*; D004926:Escherichia coli / Q000254:growth & development* / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology; D006801:Humans; D019936:Probiotics
chemical_list: D016207:Cytokines