title: Weight changes in Parkinson's disease patients after subthalamic nucleus deep brain stimulation surgery.
abstract: BACKGROUND
  After Sub-Thalamic Nucleus Deep Brain Stimulation (STN-DBS), an effective treatment for Parkinson disease patients, weight gain has been observed. As this method of treatment is only in use since two years in Iran, no information regarding its side effects (including weight gain) existed thus far.
  
  
  OBJECTIVE
  We conducted this study to evaluate the weight gain 1 and 3 months after the DBS surgery.
  
  
  METHODS
  We enrolled all patients who underwent bilateral STN-DBS in Rasool Akram Hospital affiliated to Iran University of Medical Sciences in 2008- 2009. Unified Parkinson Disease Rating Scale (UPDRS), neuropsychological assessment, pulmonary and cardiac evaluation before the surgery were carried out for all patients. They were weighted before, 1 and 3 months after the STN-DBS.
  
  
  RESULTS
  The average weight of patients was 70.7 +/- 14.4, 74.1 +/- 16.2 and 76.6 +/- 14.4 Kg before, 1 and 3 months after the STN-DBS, respectively (P < 0.037).
  
  
  CONCLUSIONS
  Our results confirm that rapid weight gain (as soon as 1 month after surgery) occurred in STN-DBS treated parkinsonian patients.
authors.affiliation: Iran University of Medical Sciences, Neurology, Rasool Akram Hospital, Tehran, Iran. moghaddasim@hotmail.com
authors.forename: Mehdi
authors.initials: M
authors.lastname: Moghaddasi
authors.forename: Mohsen
authors.initials: M
authors.lastname: Boshtam
mesh_terms: D000328:Adult; D000368:Aged; D001835:Body Weight / Q000502:physiology*; D046690:Deep Brain Stimulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000628:therapy*; D010808:Physical Examination; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020531:Subthalamic Nucleus / Q000502:physiology*; D013997:Time Factors; D015430:Weight Gain / Q000502:physiology