title: Torque teno virus viremia load size in patients with selected congenital defects of innate immunity.
abstract: Plasma loads of torque teno virus (TTV) among individuals differ extensively beginning early in life, suggesting a role for innate immunity. Here, congenital mannose-binding lectin deficiencies, but not deficiencies in respiratory ciliary function, correlated with increased TTV loads. Notably, however, the presence of either disorder was associated with particularly high TTV loads.
authors.affiliation: Virology Unit, Pisa University Hospital and Virology Section and Retrovirus Centre, Department of Experimental Pathology, University of Pisa, Via San Zeno 35-37, 56127 Pisa, Italy. fabrizio.maggi63@gmail.com
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Maggi
authors.forename: Massimo
authors.initials: M
authors.lastname: Pifferi
authors.forename: Angela
authors.initials: A
authors.lastname: Michelucci
authors.forename: Melania
authors.initials: M
authors.lastname: Albani
authors.forename: Selenia
authors.initials: S
authors.lastname: Sbranti
authors.forename: Letizia
authors.initials: L
authors.lastname: Lanini
authors.forename: Paolo
authors.initials: P
authors.lastname: Simi
authors.forename: Pierantonio
authors.initials: P
authors.lastname: Macchia
authors.forename: Mauro
authors.initials: M
authors.lastname: Pistello
authors.forename: Mauro
authors.initials: M
authors.lastname: Bendinelli
mesh_terms: D000293:Adolescent; D002648:Child; D002925:Ciliary Motility Disorders / Q000151:congenital; D004266:DNA Virus Infections / Q000821:virology*; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007153:Immunologic Deficiency Syndromes / Q000151:congenital*; D008297:Male; D037601:Mannose-Binding Lectin / Q000172:deficiency; D022783:Torque teno virus / Q000302:isolation & purification*; D019562:Viral Load; D014766:Viremia; D055815:Young Adult
chemical_list: D037601:Mannose-Binding Lectin