title: GeneReporter--sequence-based document retrieval and annotation.
abstract: GeneReporter is a web tool that reports functional information and relevant literature on a protein-coding sequence of interest. Its purpose is to support both manual genome annotation and document retrieval. PubMed references corresponding to a sequence are detected by the extraction of query words from UniProt entries of homologous sequences. Data on protein families, domains, potential cofactors, structure, function, cellular localization, metabolic contribution and corresponding DNA binding sites complement the information on a given gene product of interest.
  
  
  METHODS
  GeneReporter is available at http://www.genereporter.tu-bs.de. The web site integrates databases and analysis tools as SOAP-based web services from the EBI (European Bioinformatics Institute) and NCBI (National Center for Biotechnology Information).
authors.affiliation: Institute for Microbiology, Technische Universität Braunschweig, Braunschweig, Germany.
authors.forename: Annekathrin
authors.initials: A
authors.lastname: Bartsch
authors.forename: Boyke
authors.initials: B
authors.lastname: Bunk
authors.forename: Isam
authors.initials: I
authors.lastname: Haddad
authors.forename: Johannes
authors.initials: J
authors.lastname: Klein
authors.forename: Richard
authors.initials: R
authors.lastname: Münch
authors.forename: Thorsten
authors.initials: T
authors.lastname: Johl
authors.forename: Uwe
authors.initials: U
authors.lastname: Kärst
authors.forename: Lothar
authors.initials: L
authors.lastname: Jänsch
authors.forename: Dieter
authors.initials: D
authors.lastname: Jahn
authors.forename: Ida
authors.initials: I
authors.lastname: Retter
mesh_terms: D019295:Computational Biology; D057225:Data Mining; D030541:Databases, Genetic; D020407:Internet; D058977:Molecular Sequence Annotation; D011506:Proteins / Q000737:chemistry / Q000235:genetics; D039781:PubMed; D020539:Sequence Analysis, Protein; D017386:Sequence Homology, Amino Acid; D012984:Software
chemical_list: D011506:Proteins