title: Cancer of prostate: relief of bone pain with levodopa.
abstract: Six patients with metastatic carcinoma of the prostate were given 250 to 500 mg. of levodopa at four-hour intervals for bone pain. Four patients showed definite improvement. Based on our observation, further trial of levodopa is recommended for relief of bone pain in patients with metastatic carcinoma of the prostate.
authors.affiliation: Division of Urology, University of Health Sciences, The Chicago Medical School, Illinois, USA.
authors.forename: N
authors.initials: N
authors.lastname: Sadoughi
authors.forename: M
authors.initials: M
authors.lastname: Razvi
authors.forename: I
authors.initials: I
authors.lastname: Bush
authors.forename: R
authors.initials: R
authors.lastname: Ablin
authors.forename: P
authors.initials: P
authors.lastname: Guinan
mesh_terms: D001859:Bone Neoplasms / Q000150:complications* / Q000556:secondary*; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D010146:Pain / Q000188:drug therapy* / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000473:pathology*
chemical_list: D007980:Levodopa