title: Constitutional growth delay pattern of growth in velo-cardio-facial syndrome: longitudinal follow up and final height of two cases.
abstract: We report two patients with velo-cardio-facial syndrome (VCFS) who were admitted to our pediatric endocrinology clinic because of short stature and followed longitudinally until attainment of final height. Both patients followed a growth pattern consistent with constitutional delay of puberty with normal and near normal final height. Case 2 also had partial growth hormone (GH) deficiency and severe short stature (height SDS -3.4 SDS), but showed spontaneous catch-up and ended up with a final height of -2 SDS. These cases suggest that short stature in children with VCFS is due to a pattern of growth similar to that observed in constitutional delay of growth and puberty.
authors.affiliation: Marmara University, Department of Pediatric Endocrinology, Istanbul, Turkey. serapdemircioglu@yahoo.com
authors.forename: Serap
authors.initials: S
authors.lastname: Turan
authors.forename: Nihal
authors.initials: N
authors.lastname: Ozdemir
authors.forename: Tülay
authors.initials: T
authors.lastname: Güran
authors.forename: Figen
authors.initials: F
authors.lastname: Akalın
authors.forename: Teoman
authors.initials: T
authors.lastname: Akçay
authors.forename: Canan
authors.initials: C
authors.lastname: Ayabakan
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Yılmaz
authors.forename: Abdullah
authors.initials: A
authors.lastname: Bereket
mesh_terms: D000293:Adolescent; D001827:Body Height; D002648:Child; D004062:DiGeorge Syndrome / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000209:etiology* / Q000503:physiopathology; D006801:Humans