title: The Guy's stone score--grading the complexity of percutaneous nephrolithotomy procedures.
abstract: OBJECTIVE
  To report the development and validation of a scoring system, the Guy's stone score, to grade the complexity of percutaneous nephrolithotomy (PCNL). Currently, no standardized method is available to predict the stone-free rate after PCNL.
  
  
  METHODS
  The Guy's stone score was developed through a combination of expert opinion, published data review, and iterative testing. It comprises 4 grades: grade I, solitary stone in mid/lower pole or solitary stone in the pelvis with simple anatomy; grade II, solitary stone in upper pole or multiple stones in a patient with simple anatomy or a solitary stone in a patient with abnormal anatomy; grade III, multiple stones in a patient with abnormal anatomy or stones in a caliceal diverticulum or partial staghorn calculus; grade IV, staghorn calculus or any stone in a patient with spina bifida or spinal injury. It was assessed for reproducibility using the kappa coefficient and validated on a prospective database of 100 PCNL procedures performed in a tertiary stone center. The complications were graded using the modified Clavien score. The clinical outcomes were recorded prospectively and assessed with multivariate analysis.
  
  
  RESULTS
  The Guy's stone score was the only factor that significantly and independently predicted the stone-free rate (P = .01). It was found to be reproducible, with good inter-rater agreement (P = .81). None of the other factors tested, including stone burden, operating surgeon, patient weight, age, and comorbidity, correlated with the stone-free rate.
  
  
  CONCLUSIONS
  The Guy's stone score accurately predicted the stone-free rate after PCNL. It was easy to use and reproducible.
authors.affiliation: Stone Unit, Guy's and St. Thomas' National Health Services Foundation Hospital, London, United Kingdom. kay.thomas@gstt.nhs.uk
authors.forename: Kay
authors.initials: K
authors.lastname: Thomas
authors.forename: Naomi C
authors.initials: NC
authors.lastname: Smith
authors.forename: Nicholas
authors.initials: N
authors.lastname: Hegarty
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Glass
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000145:classification* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009403:Nephrostomy, Percutaneous / Q000379:methods*; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D055815:Young Adult