title: Efficacy of liquid spray decontaminants for inactivation of Bacillus anthracis spores on building and outdoor materials.
abstract: OBJECTIVE
  To obtain data on the efficacy of various liquid and foam decontamination technologies to inactivate Bacillus anthracis Ames and Bacillus subtilis spores on building and outdoor materials.
  
  
  RESULTS
  Spores were inoculated onto test coupons and positive control coupons of nine different materials. Six different sporicidal liquids were spray-applied to the test coupons and remained in contact for exposure times ranging from 10 to 70 min. Following decontamination, spores were recovered from the coupons and efficacy was quantified in terms of log reduction.
  
  
  CONCLUSIONS
  The hydrogen peroxide/peracetic acid products were the most effective, followed by decontaminants utilizing hypochlorous acid chemistry. Decontamination efficacy varied by material type.
  
  
  CONCLUSIONS
  The study results may be useful in the selection of technologies to decontaminate buildings and outdoor areas in the event of contamination with B. anthracis spores. These results may also facilitate selection of decontaminant liquids for the inactivation of other spore-forming infectious disease agents.
authors.affiliation: United States Environmental Protection Agency, National Homeland Security Research Center, Research Triangle Park, NC, USA. wood.joe@epa.gov
authors.forename: J P
authors.initials: JP
authors.lastname: Wood
authors.forename: Y W
authors.initials: YW
authors.lastname: Choi
authors.forename: J V
authors.initials: JV
authors.lastname: Rogers
authors.forename: T J
authors.initials: TJ
authors.lastname: Kelly
authors.forename: K B
authors.initials: KB
authors.lastname: Riggs
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Willenberg
mesh_terms: D001408:Bacillus anthracis / Q000187:drug effects*; D001412:Bacillus subtilis / Q000187:drug effects; D003252:Construction Materials / Q000382:microbiology*; D003666:Decontamination / Q000379:methods*; D004203:Disinfection / Q000379:methods; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D006997:Hypochlorous Acid / Q000494:pharmacology; D010463:Peracetic Acid / Q000494:pharmacology*; D013171:Spores, Bacterial / Q000187:drug effects
chemical_list: D006997:Hypochlorous Acid; D006861:Hydrogen Peroxide; D010463:Peracetic Acid