title: [Transient splenial lesion in influenza A H1N1 2009 infection].
abstract: Severe neurologic complications have been rarely reported during novel pandemic influenza A(H1N1) virus infections. We describe the case of an 10-year-old boy with new onset seizures and proven influenza A(H1N1) 2009 infection showing a reversible hyperintense lesion in the splenium of the corpus callosum on T2-weighted and FLAIR magnetic resonance images without contrast enhancement. Transient splenial lesions have been described in the context of virus encephalopathy and do not require specific treatment.
authors.affiliation: Zentrum für Kinderheilkunde, Universitätsklinikum Bonn, Adenauerallee 119, Bonn, Germany. katharina.linden@ukb.uni-bonn.de
authors.forename: K
authors.initials: K
authors.lastname: Linden
authors.forename: O
authors.initials: O
authors.lastname: Moser
authors.forename: A
authors.initials: A
authors.lastname: Simon
authors.forename: A-M
authors.initials: AM
authors.lastname: Eis-Hübinger
authors.forename: G
authors.initials: G
authors.lastname: Fleischhack
authors.forename: M
authors.initials: M
authors.lastname: Born
authors.forename: H
authors.initials: H
authors.lastname: Tschampa
authors.forename: T
authors.initials: T
authors.lastname: Rosenbaum
authors.forename: B
authors.initials: B
authors.lastname: Köster
authors.forename: M
authors.initials: M
authors.lastname: Lentze
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D003337:Corpus Callosum / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D004359:Drug Therapy, Combination; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000188:drug therapy; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy; D000077287:Levetiracetam; D008279:Magnetic Resonance Imaging; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use; D058873:Pandemics; D010889:Piracetam / Q000031:analogs & derivatives / Q000627:therapeutic use; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D000927:Anticonvulsants; D000998:Antiviral Agents; D053139:Oseltamivir; D000077287:Levetiracetam; D000212:Acyclovir; D010889:Piracetam