title: Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction.
abstract: OBJECTIVE
  Strain rate imaging techniques have been proposed for the detection of ischemic or viable myocardium in coronary artery disease, which is still a challenge in clinical cardiology. This retrospective comparative study analyzed regional left ventricular function and scaring with two-dimensional strain (2DS) in the first 4 to 10 days after acute anterior myocardial infarction (AMI).
  
  
  RESULTS
  The study population consisted of 32 AMI patients with an LAD occlusion and successful reperfusion. The assessment of peak systolic 2DS and peak systolic strain rate (SR) was performed segment-oriented with the angle-independent speckle tracking algorithm Velocity Vector Imaging (VVI). The infarcted, adjacent and non-infarcted segments were revealed by late enhancement MRI (LE-MRI), which was used as reference for the comparison with 2DS. The infarcted segments showed a significant decrease of tissue velocities, 2DS and SR in comparison to the non-affected segments.
  
  
  CONCLUSIONS
  2DS and SR as assessed by VVI seem to be a suitable approach for echocardiographic quantification of global and regional myocardial function as well as a promising tool for multimodal risk stratification after anterior AMI.
authors.affiliation: Department of Cardiology and Angiology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany. Thomas.Butz@Marienhospital-Herne.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Butz
authors.forename: Corinna N
authors.initials: CN
authors.lastname: Lang
authors.forename: Marc
authors.initials: M
authors.lastname: van Bracht
authors.forename: Magnus W
authors.initials: MW
authors.lastname: Prull
authors.forename: Hakan
authors.initials: H
authors.lastname: Yeni
authors.forename: Petra
authors.initials: P
authors.lastname: Maagh
authors.forename: Gunnar
authors.initials: G
authors.lastname: Plehn
authors.forename: Axel
authors.initials: A
authors.lastname: Meissner
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Trappe
mesh_terms: D000328:Adult; D000368:Aged; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012189:Retrospective Studies