title: Computed tomography in children: multicenter cohort study design for the evaluation of cancer risk.
abstract: Exposure to ionizing radiation is a known risk factor for cancer. Cancer risk is highest after exposure in childhood. The computed tomography is the major contributor to the average, individual radiation exposure. Until now the association has been addressed only in statistical modeling. We present the first feasible study design on childhood cancer risk after exposure to computed tomography.
authors.affiliation: Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre Mainz, Obere Zahlbacher Street 69, 55131, Mainz, Germany. krille@imbei.uni-mainz.de
authors.forename: L
authors.initials: L
authors.lastname: Krille
authors.forename: A
authors.initials: A
authors.lastname: Jahnen
authors.forename: P
authors.initials: P
authors.lastname: Mildenberger
authors.forename: K
authors.initials: K
authors.lastname: Schneider
authors.forename: G
authors.initials: G
authors.lastname: Weisser
authors.forename: H
authors.initials: H
authors.lastname: Zeeb
authors.forename: M
authors.initials: M
authors.lastname: Blettner
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005240:Feasibility Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D010865:Pilot Projects; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed / Q000009:adverse effects*