title: Adenocarcinoma of the esophagus presenting as choroidal metastasis.
abstract: Adenocarcinoma of the esophagus is an exceedingly rare cause of choroidal metastasis. We report the case of a 48-year-old Caucasian male with a 2-month history of decreased vision and dysphagia. Ophthalmologic examination revealed bilateral choroidal masses and an exudative retinal detachment in the left eye. Gastroduodenoscopy revealed a circumferential mass in the distal esophagus at 30 cm extending into and involving the gastroesophageal junction. Endoscopic biopsy disclosed an invasive, poorly differentiated adenocarcinoma. Systemic workup revealed widespread metastatic changes in the pericardium, liver, and left adrenal gland, and a right pleural effusion. The patient's condition rapidly deteriorated, and he passed away 40 days after initial presentation. To our knowledge, this represents the first case of choroidal metastasis as the initial manifestation of esophageal adenocarcinoma.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA. dean_eliott@meei.harvard.edu
authors.forename: D
authors.initials: D
authors.lastname: Eliott
authors.forename: H
authors.initials: H
authors.lastname: Salehi-Had
authors.forename: O Z
authors.initials: OZ
authors.lastname: Plous
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000556:secondary*; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged