title: [Age-related changes in the level of serum bone markers in healthy children].
abstract: Age-related changes in the blood level of bone metabolic markers were compared in healthy children living in different geographical regions. The absolute value of carboxy-terminal telopeptide of type 1 collagen type 1 (beta-CrossLaps) and that of total procollagen type 1 amino-terminal propeptide (PINP) were found to depend on living conditions and the nature of changes in the serum markers of bone metabolism was related to the processes of natural growth and development in children. A child's individual growth curve can be used to identify target groups for the prevention of osteopenia.
authors.forename: T M
authors.initials: TM
authors.lastname: Ivashkina
authors.forename: T N
authors.initials: TN
authors.lastname: Kotova
authors.forename: P Sh
authors.initials: PSh
authors.lastname: Omarova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Khlekhlina
authors.forename: V S
authors.initials: VS
authors.lastname: Berestovskaia
authors.forename: T S
authors.initials: TS
authors.lastname: Ponkratova
mesh_terms: D000293:Adolescent; D000367:Age Factors; D015415:Biomarkers / Q000097:blood; D001846:Bone Development; D001842:Bone and Bones / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D003094:Collagen / Q000097:blood; D024042:Collagen Type I / Q000097:blood; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides / Q000097:blood; D011347:Procollagen / Q000097:blood; D012016:Reference Values
chemical_list: D015415:Biomarkers; D024042:Collagen Type I; D010446:Peptide Fragments; D010455:Peptides; D011347:Procollagen; C052929:collagen type I trimeric cross-linked peptide; C110762:glutamyl-lysyl-alanyl-histidyl-aspartyl-glycyl-glycyl-arginine; C047202:procollagen Type I N-terminal peptide; D003094:Collagen