title: [Respiratory system at high altitude: pathophysiology and novel therapy options].
abstract: This mini-review conveys information on lung function in hypoxia. Included are presentations of shape and layering of the atmosphere, physiologic basics of lung function at high altitude, pathophysiology of high altitude pulmonary edema (HAPE) and of current and potential therapy approaches for HAPE.
authors.affiliation: Section of Respiratory and Altitude Medicine, Medizinische Universität Innsbruck, Innsbruck, Austria.
authors.forename: Suzan S
authors.initials: SS
authors.lastname: Trübsbach
authors.forename: Iris
authors.initials: I
authors.lastname: Pircher
authors.forename: Benedict
authors.initials: B
authors.lastname: Treml
authors.forename: Alex
authors.initials: A
authors.lastname: Löckinger
authors.forename: Axel T
authors.initials: AT
authors.lastname: Kleinsasser
mesh_terms: D000532:Altitude Sickness / Q000150:complications / Q000503:physiopathology; D000818:Animals; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000503:physiopathology; D000860:Hypoxia / Q000150:complications* / Q000503:physiopathology*; D008168:Lung / Q000503:physiopathology*; D008954:Models, Biological; D012119:Respiration