title: Koebner's phenomenon in vitiligo: European position paper.
abstract: Koebner's phenomenon (KP) has been observed in a number of skin diseases, including vitiligo. Its clinical significance in vitiligo with respect to disease activity and course is still debatable, while its relevance for surgical techniques has been demonstrated in some reports. We present a literature review on the currently known facts about KP in vitiligo, including details of clinical, experimental, and histopathological changes. The consensus view is that there are still no methods to define and assess KP in vitiligo. A new classification is proposed to allow an evaluation of KP in daily practice or in experimental studies. However, many unanswered questions still remain after redefining KP in patients with vitiligo. Active research focusing on KP in vitiligo may not only provide unexpected clues in the pathogenesis of vitiligo but also help to tailor novel therapies against this chronic and often psychologically devastating skin disease.
authors.affiliation: Department of Dermatology, Ghent University Hospital, Ghent, Belgium. Nanja.vangeel@UGent.be
authors.forename: Nanja
authors.initials: N
authors.lastname: van Geel
authors.forename: Reinhart
authors.initials: R
authors.lastname: Speeckaert
authors.forename: Alain
authors.initials: A
authors.lastname: Taieb
authors.forename: Mauro
authors.initials: M
authors.lastname: Picardo
authors.forename: Markus
authors.initials: M
authors.lastname: Böhm
authors.forename: David J
authors.initials: DJ
authors.lastname: Gawkrodger
authors.forename: Karin
authors.initials: K
authors.lastname: Schallreuter
authors.forename: Dorothy C
authors.initials: DC
authors.lastname: Bennett
authors.forename: Wietze
authors.initials: W
authors.lastname: van der Veen
authors.forename: Maxine
authors.initials: M
authors.lastname: Whitton
authors.forename: Silvia
authors.initials: S
authors.lastname: Moretti
authors.forename: Wiete
authors.initials: W
authors.lastname: Westerhof
authors.forename: Khaled
authors.initials: K
authors.lastname: Ezzedine
authors.forename: Yvon
authors.initials: Y
authors.lastname: Gauthier
mesh_terms: D000818:Animals; D002908:Chronic Disease; D006801:Humans; D014820:Vitiligo / Q000378:metabolism* / Q000473:pathology* / Q000503:physiopathology* / Q000628:therapy