title: N-acylsulfonamide assisted tandem C-H olefination/annulation: synthesis of isoindolinones.
abstract: A tandem C-H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.
authors.affiliation: Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. chen.zhu@utsouthwestern.edu
authors.forename: Chen
authors.initials: C
authors.lastname: Zhu
authors.forename: J R
authors.initials: JR
authors.lastname: Falck
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D013449:Sulfonamides / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007211:Indoles; D007659:Ketones; D013449:Sulfonamides