title: Dynamic kinetic resolution in the stereoselective synthesis of 4,5-diaryl cyclic sulfamidates by using chiral rhodium-catalyzed asymmetric transfer hydrogenation.
abstract: The dynamic kinetic resolution of 4,5-diaryl cyclic sulfamidate imines was achieved via asymmetric transfer hydrogenation using a HCO(2)H/Et(3)N mixture as the hydrogen source and chiral Rh catalysts (R,R)- or (S,S)-RhCl(TsDPEN)Cp* affording the corresponding cyclic sulfamidates in good yields with up to >20 : 1 dr and up to >99% ee.
authors.affiliation: Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong, Daejeon 305-600, Korea.
authors.forename: Juae
authors.initials: J
authors.lastname: Han
authors.forename: Soyeong
authors.initials: S
authors.lastname: Kang
authors.forename: Hyeon-Kyu
authors.initials: HK
authors.lastname: Lee
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013451:Sulfonic Acids / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007097:Imines; D013451:Sulfonic Acids; C005741:sulfamic acid; D012238:Rhodium