title: [Diagnosis and treatment of morbus Osler].
abstract: Morbus Osler or hereditary haemorrhagic telangiectasia (HHT) is a genetic disorder resulting in development of arteriovenous malformations in the mucosa and in visceral organs. The most common symptom is epistaxis. The disease may, however, cause a variety of other serious manifestations such as pulmonary arteriovenous malformations (PAVM), cerebral arteriovenous malformations (CAVM) and gastrointestinal bleeding. Collaboration between various medical specialties is essential in order to provide an up-to-date treatment and thorough work-up in the individual patient. Disregard of symptoms may result in substantial morbidity and may have serious consequences. This overview presents our current understanding of HHT.
authors.affiliation: Øre-næse-hals-kirurgisk Afdeling F, Odense Universitetshospital, 5000 Odense C, Denmark. anette.kjeldsen@ouh.regionsyddanmark.dk
authors.forename: Anette Drøhse
authors.initials: AD
authors.lastname: Kjeldsen
authors.forename: Poul Erik
authors.initials: PE
authors.lastname: Andersen
authors.forename: Pernille Mathiesen
authors.initials: PM
authors.lastname: Tørring
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001165:Arteriovenous Malformations / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D004844:Epistaxis / Q000175:diagnosis; D005260:Female; D006801:Humans; D033183:Interdisciplinary Communication; D009092:Mucous Membrane / Q000473:pathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis; D011788:Quality of Life; D011859:Radiography; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D000925:Anticoagulants