title: Pigmented villonodular synovitis of the temporomandibular joint: case report and review of the literature.
abstract: Pigmented villonodular synovitis (PVNS) is an aggressive proliferative lesion that usually involves the synovial tissues of big joints. To date, there are ∼52 cases of PVNS affecting the temporomandibular joint reported in the English-language literature, about one-third of them exhibiting intracranial involvement. We herein describe an additional case of PVNS of the temporomandibular joint with skull base invasion affecting a 26-year-old male patient and discuss its clinicopathologic features considering previously published cases. Histopathology and imaging evaluation are important for the diagnosis of PVNS, which should be included in the differential diagnosis of preauricular aggressive swellings.
authors.affiliation: Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil. marioromanach@yahoo.com.br
authors.forename: Mário José
authors.initials: MJ
authors.lastname: Romañach
authors.forename: Bernardo Ferreira
authors.initials: BF
authors.lastname: Brasileiro
authors.forename: Jorge Esquiche
authors.initials: JE
authors.lastname: León
authors.forename: Daniel Berreta
authors.initials: DB
authors.lastname: Alves
authors.forename: Oslei Paes
authors.initials: OP
authors.lastname: de Almeida
authors.forename: Pablo Agustin
authors.initials: PA
authors.lastname: Vargas
mesh_terms: D000328:Adult; D001847:Bone Diseases / Q000175:diagnosis; D002813:Chondrosarcoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006485:Hemosiderin / Q000032:analysis; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis; D016059:Range of Motion, Articular / Q000502:physiology; D019291:Skull Base / Q000473:pathology; D013586:Synovitis, Pigmented Villonodular / Q000175:diagnosis*; D013705:Temporomandibular Joint Disorders / Q000175:diagnosis*; D014746:Vimentin / Q000032:analysis
chemical_list: D014746:Vimentin; D006485:Hemosiderin