title: Emerging role of sildenafil in neonatology.
abstract: Over the last few years, sildenafil is increasingly being used in the neonatal ICU for a variety of indications. The use is even more so in the developing world due to the limited availability of nitric oxide and extracorporeal membrane oxygenation (ECMO). There are still no clear cut guidelines for its use. At present the drug appears relatively safe and effective when other treatment options have been optimized. However, the use of sildenafil must be monitored and reported. Due to its easy availability and ease of administration we must guard against its inappropriate use.
authors.affiliation: Department of Pediatrics, Division of Neonatology, Max Super Speciality Hospital, Saket, New Delhi, India. m.malik@maxhealthcare.com
authors.forename: Manish
authors.initials: M
authors.lastname: Malik
authors.forename: Rahul
authors.initials: R
authors.lastname: Nagpal
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D010547:Persistent Fetal Circulation Syndrome / Q000188:drug therapy*; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate