title: [Giant cell granuloma outside the jaw three cases and literature review].
abstract: OBJECTIVE
  To investigate the clinicopathological features, diagnosis and treatment of giant cell granuloma outside the jaw.
  
  
  METHODS
  The clinical and pathological datas of 3 cases in nasopharynx, temporal bone and maxillary sinus were analyzed retrospectively. The relevant literatures were also reviewed.
  
  
  RESULTS
  The patients presented with local painless mass, part of which were aggressive. Histopathological feature was, replacement of the normal bone structure with proliferating fibrous tissue containing numerous giant cells was shown.
  
  
  CONCLUSIONS
  Giant cell granuloma outside the jaw was a non-neoplastic lesion, and extremely rare. It was somewhat difficult to make a correct diagnosis. Combining the clinical data and pathological feature were more helpful to the diagnosis. Total surgical resection was an effective therapeutic method.
authors.affiliation: Department of Pathology, EENT Hospital of Fudan University, Shanghai, 200031, China. lishimin@163.com
authors.forename: Shimin
authors.initials: S
authors.lastname: Li
authors.forename: Shuyi
authors.initials: S
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006801:Humans; D007568:Jaw; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology*; D009305:Nasopharynx / Q000473:pathology*; D013701:Temporal Bone / Q000473:pathology*; D055815:Young Adult