title: Application of sonoelastography: comparison of performance between mass and non-mass lesion.
abstract: OBJECTIVE
  The purpose of this study was to determine the performance of the conventional ultrasonography (US) and sonoelastography (SE) in three conditions of all lesions, confined to mass, and confined to non-mass lesion and to compare the performance of each modality between mass and non-mass lesion.
  
  
  METHODS
  A total 364 patients with 375 lesions were evaluated with US and subsequently SE before performing US-guided biopsy. Two radiologists retrospectively analyzed conventional US and elasticity images by consensus. The US findings were classified as mass or non-mass lesion. With final pathology as reference, in each case of all lesions, masses, and non-mass lesions, areas under the ROC curves (Az) were calculated and compared for the two techniques. The comparison of Az values between the curves for US and SE, and between the curves for mass and non-mass lesion was performed.
  
  
  RESULTS
  Among 375 lesions, 104 (28%) lesions were malignant and 271 (72%) lesions were benign. 36 (9.6%) of 375 lesions were classified as non-mass lesion at US. There were statistically significant difference of performance between US and SE in cases of all lesion (p=0.003) and mass (p=0.023). However, there was no statistically significant difference of performance in case of non-mass lesion (p=0.5). Comparisons of the Az values of US and SE between mass and non-mass lesions were not statistically significant (p=0.745, p=0.415, respectively).
  
  
  CONCLUSIONS
  There was no statistically significant difference of performance of US and SE between mass and non-mass lesion.
authors.affiliation: Department of Radiology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul 135-710, Korea. mathilda0330@gmail.com
authors.forename: Eun Sook
authors.initials: ES
authors.lastname: Ko
authors.forename: Hye Young
authors.initials: HY
authors.lastname: Choi
authors.forename: Rock Bum
authors.initials: RB
authors.lastname: Kim
authors.forename: Woo-Chul
authors.initials: WC
authors.lastname: Noh
mesh_terms: D000328:Adult; D000368:Aged; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015995:Prevalence; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D012680:Sensitivity and Specificity