title: Comparative growth performance of pigs immunised with a gonadotrophin releasing factor vaccine with surgically castrated pigs and entire boars raised under conventionally managed conditions.
abstract: The objective of this study was to determine the effect of using a gonadotrophin releasing factor (GnRF) vaccine on growth performance of male pigs. Vaccinated pigs were compared with surgically castrated pigs and entire males under conventionally managed farm conditions. Male pigs were randomly assigned to three treatment groups: pigs surgically castrated during the first week of life (group "C", n=274), pigs immunised twice during the fattening period with a GnRF vaccine, the first when 13-14 weeks of age and the second when 20-21 weeks of age (group "V" n=280) and entire males (group "E", n=56). Average daily weight gain (ADG) was measured during the study. Additionally, feed conversion ratio (FCR) as defined by feed intake/weight gain and feed consumption was assessed during the fattening period. No difference in the ADG during the fattening period could be determined between "C" and "V". From the start of the study until slaughter at study day 160/173 the ADG in group "E" was lower (625 g/day; P) than in group "C" (681 g/day; P < 0.001) and group "V" (675 g/day; P < 0.01). The FCR during the fattening period until study day 160, three days before the first batch of pigs were slaughtered at 24-25 weeks of age, was higher in group"C" (2.72 kg feed intake/kg weight gain) compared with group "V" (2.44 kg feed intake/kg weight gain; P < 0.001) and group "E" (2.44 kg feed intake/kg weight gain; P <0.01). Pigs in group "V" performed similarly to those in group "E" until the second vaccination (day 135) after which time they showed a substantial increase in feed intake and ADG, while retaining an FCR advantage over group C.
authors.affiliation: Field Station for Epidemiology, University of Veterinary Medicine Hannover, Bakum, Germany.
authors.forename: Thilo
authors.initials: T
authors.lastname: Fuchs
authors.forename: Heiko
authors.initials: H
authors.lastname: Nathues
authors.forename: Annika
authors.initials: A
authors.lastname: Koehrmann
authors.forename: Stuart
authors.initials: S
authors.lastname: Andrews
authors.forename: Fiona
authors.initials: F
authors.lastname: Brock
authors.forename: Günter
authors.initials: G
authors.lastname: Klein
authors.forename: Elisabeth
authors.initials: E
authors.lastname: grosse Beilage
mesh_terms: D000818:Animals; D004435:Eating; D007987:Gonadotropin-Releasing Hormone / Q000276:immunology*; D007114:Immunization / Q000662:veterinary*; D007117:Immunization, Secondary / Q000662:veterinary; D008297:Male; D008460:Meat / Q000592:standards; D009919:Orchiectomy / Q000662:veterinary*; D013552:Swine / Q000254:growth & development* / Q000276:immunology / Q000601:surgery; D014612:Vaccines; D015430:Weight Gain
chemical_list: D014612:Vaccines; D007987:Gonadotropin-Releasing Hormone