title: Uterine artery occlusion for treatment of symptomatic uterine myomas.
abstract: OBJECTIVE
  To compare the effectiveness and safety of uterine artery occlusion by laparoscopy versus embolization as a treatment modality for symptomatic uterine fibroids.
  
  
  METHODS
  Ninety-six premenopausal women with symptomatic uterine leiomyomata were studied. None of them desired further pregnancy. They were randomized to treatment either by laparoscopic occlusion (group 1) or by radiologic embolization of uterine arteries (group 2). The primary outcome measure was patient satisfaction as regards menstrual blood loss compared with pretreatment loss. Secondary outcome measures included postoperative pain, complications, secondary interventions, and failures.
  
  
  RESULTS
  Ninety women were followed for 1, 3, 6, and 12 months after both procedures. The primary outcome was comparable between the 2 groups (86.7% after laparoscopic occlusion versus 88.8% after embolization, with no statistically significant difference). After 12 months of follow-up, more patients resumed heavy periods in the uterine artery occlusion group [4/45 patients, 8.8% in occlusion group compared with 3/45 (6.6%) in embolization group, P=0.044].
  
  
  CONCLUSIONS
  Both laparoscopic occlusion and superselective embolization of uterine arteries improved clinical symptoms in the majority of patients. At 12-month follow-up, embolization might be more effective.
authors.affiliation: Department of Obstetrics and Gynecology, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Egypt. adelsaadhelal@yahoo.com
authors.forename: Adel
authors.initials: A
authors.lastname: Helal
authors.forename: Abd El-Mageed
authors.initials: Ael-M
authors.lastname: Mashaly
authors.forename: Talal
authors.initials: T
authors.lastname: Amer
mesh_terms: D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007889:Leiomyoma / Q000098:blood supply / Q000628:therapy*; D008026:Ligation / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D055988:Uterine Artery / Q000601:surgery*; D014594:Uterine Neoplasms / Q000098:blood supply / Q000628:therapy*