title: Enantioseparation by chromatographic and electromigration techniques using ligand-exchange as chiral separation principle.
abstract: This article gives a short overview of the application of the principle of chiral ligand-exchange in HPLC, CE, and CEC. Since its introduction by Davankov, more than thousand articles have appeared in this field. Citing all these papers would extend the scope of this review-it would fill several books. Therefore only some milestones are mentioned in this article and it will focus on our own activities in this field. Some new developments are mentioned, and selected biochemical and biomedical application are presented.
authors.affiliation: Institute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, Karl-Franzens-University, Graz, Austria. martin.schmid@uni-graz.at
authors.forename: Martin G
authors.initials: MG
authors.lastname: Schmid
authors.forename: Gerald
authors.initials: G
authors.lastname: Gübitz
mesh_terms: D053801:Capillary Electrochromatography; D002851:Chromatography, High Pressure Liquid; D019075:Electrophoresis, Capillary; D008024:Ligands; D009930:Organic Chemicals / Q000302:isolation & purification*; D009942:Organometallic Compounds / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D008024:Ligands; D009930:Organic Chemicals; D009942:Organometallic Compounds