title: Impact of submucous myoma on the severity of anemia.
abstract: OBJECTIVE
  To analyze the impact of the diameter (myoma-φ) and the uterine cavity protruding proportion (protruding %) of the submucous myoma on serum hemoglobin (Hb) level.
  
  
  METHODS
  Retrospective descriptive study.
  
  
  METHODS
  Tertiary university hospital.
  
  
  METHODS
  Two hundred fifty-nine women with a single submucous myoma.
  
  
  METHODS
  Transvaginal ultrasound examination and office hysteroscopy.
  
  
  METHODS
  Myoma-φ and protruding % were determined with transvaginal ultrasound scan and office hysteroscopy. Menorrhagic period (months) and serum Hb were recorded within 2 weeks of these examinations.
  
  
  RESULTS
  Serum Hb negatively correlated with myoma-φ, protruding %, and menorrhagic period. The negative association between serum Hb and protruding % was even more prominent after adjusting for myoma-φ. Multivariate regression analysis revealed that myoma-φ and protruding %, after adjusting for the confounding effect of menorrhagic period, maintained a strongly negative correlation with serum Hb level. When myoma-φ was <2 cm, however, the serum Hb levels were similar regardless of the protruding %.
  
  
  CONCLUSIONS
  For women with a single submucous myoma, myoma-φ and protruding % can determine the serum Hb level significantly . As myoma-φ and protruding % increased, the serum Hb level decreased accordingly.
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Jehn-Hsiahn
authors.initials: JH
authors.lastname: Yang
authors.forename: Mei-Jou
authors.initials: MJ
authors.lastname: Chen
authors.forename: Chin-Der
authors.initials: CD
authors.lastname: Chen
authors.forename: Chi-Ling
authors.initials: CL
authors.lastname: Chen
authors.forename: Hong-Nerng
authors.initials: HN
authors.lastname: Ho
authors.forename: Yu-Shih
authors.initials: YS
authors.lastname: Yang
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures / Q000009:adverse effects; D000740:Anemia / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015907:Hysteroscopy / Q000009:adverse effects / Q000534:rehabilitation; D007889:Leiomyoma / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery*; D008595:Menorrhagia / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000209:etiology; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology; D019106:Postoperative Hemorrhage / Q000453:epidemiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D006454:Hemoglobins