title: Eremophilane-type sesquiterpene lactones from Ligularia hodgsonii Hook.
abstract: A dimeric eremophilane sesquiterpene lactone with a cyclobutane ring, biliguhodgsonolide (1) and an uncommon seco-sesquiterpene derivative, (4S,5S,6R,10R)-8,9-seco-12-hydroxyeremophil-7(11)-en-14,6;12,8-diolid-9-al (2), were isolated from the roots and rhizomes of Ligularia hodgsonii Hook. Their structures, including the absolute stereochemistry, were elucidated by spectroscopic data and CD analysis. The cyclobutane ring was confirmed by single-crystal X-ray diffraction.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Huang
authors.forename: Yang-Jun
authors.initials: YJ
authors.lastname: Xu
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Liu
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Liu
authors.forename: Ji-Ning
authors.initials: JN
authors.lastname: Shang
authors.forename: Guang-Tian
authors.initials: GT
authors.lastname: Han
authors.forename: Ming-Jun
authors.initials: MJ
authors.lastname: Yao
authors.forename: Cheng-Shan
authors.initials: CS
authors.lastname: Yuan
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D008958:Models, Molecular; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D000081223:Polycyclic Sesquiterpenes; D027343:Rhizome / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D013237:Stereoisomerism
chemical_list: D007783:Lactones; D009281:Naphthalenes; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds