title: Synthesis of Polyampholyte Comb-Type Copolymers Consisting of a Poly(L-lysine) Backbone and Hyaluronic Acid Side Chains for DNA Carrier.
abstract: Polycations have been used as nonviral gene carriers because the polycations and DNAs form stable complexes in a noncovalent manner (1-3). The polycations, e.g., poly(L-lysine) (PLL), are reported to be conjugated with several ligands for targeted gene delivery (4-8). The physicochemical properties of the DNA complexes have been described as factors that influence transfection activity (9-11).
authors.affiliation: Department of Biomolecular Engineering, Institute of Technology, Tokyo, Yokohama, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Maruyama
authors.forename: Y
authors.initials: Y
authors.lastname: Takei