title: Clinical and pathologic eyelid alterations in a patient with Darier disease.
abstract: Darier disease (DD) is a rare autosomal dominant dermatosis that has infrequent ocular manifestations, especially those involving the eyelids. The authors describe a patient with long-standing DD who presented with both classic and unique clinical findings. Eyelid biopsy samples studied with electron microscopy demonstrated histopathological changes consistent with DD. The authors postulate how clinical findings not previously reported as "classic" to DD may be associated. To the authors' knowledge, electron micrographs detailing changes associated with DD have not been published for eyelid tissue.
authors.affiliation: Division of Ophthalmology, Section Oculofacial Plastic and Reconstructive Surgery, OhioHealth/Doctor's Hospital, Columbus, Ohio, USA. dsp4000@aol.com
authors.forename: Craig
authors.initials: C
authors.lastname: Czyz
authors.forename: Pooja
authors.initials: P
authors.lastname: Sharma
authors.forename: Hans E
authors.initials: HE
authors.lastname: Grossniklaus
authors.forename: Jill A
authors.initials: JA
authors.lastname: Foster
authors.forename: Kenneth V
authors.initials: KV
authors.lastname: Cahill
mesh_terms: D007644:Darier Disease / Q000473:pathology* / Q000601:surgery; D005141:Eyelid Diseases / Q000473:pathology* / Q000601:surgery; D005143:Eyelids / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008875:Middle Aged