title: Prostaglandin D₂ receptor CRTH2 antagonists for the treatment of inflammatory diseases.
authors.affiliation: Chemistry Research and Discovery, Amgen Inc., One Amgen Center Dr. Thousand Oaks, CA 91320, USA.
authors.forename: Jian Jeffrey
authors.initials: JJ
authors.lastname: Chen
authors.forename: Alison L
authors.initials: AL
authors.lastname: Budelsky
mesh_terms: D000085:Acetates / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology; D002227:Carbazoles / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D007210:Indoleacetic Acids / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011971:Receptors, Immunologic / Q000037:antagonists & inhibitors* / Q000276:immunology; D011982:Receptors, Prostaglandin / Q000037:antagonists & inhibitors* / Q000276:immunology; D013449:Sulfonamides / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000085:Acetates; D002227:Carbazoles; D007210:Indoleacetic Acids; D011971:Receptors, Immunologic; D011982:Receptors, Prostaglandin; D013449:Sulfonamides; C063119:ramatroban; C036293:prostaglandin D2 receptor