title: Intraabdominal mass as presentation of colonic mucormycosis in a child with acute lymphoblastic leukemia.
abstract: Gastrointestinal mucormycosis with clinical presentation as an abdominal mass has been rarely reported in the current literature. In this observation, We report an unusual case of a child with acute lymphoblastic leukemia and neutropenic fever. During hospitalization, increasing abdominal pain and distension occurred, and initially treatments with broad-spectrum antibiotics were administered. However, the symptoms/signs progressed with the development of peritonitis and a palpated mass over the right lower quarter of the abdomen. Imaging studies showed ascending colon perforation with abscess formation. Right hemicolectomy was performed and colonic mucormycosis was confirmed on histologic examination and ascitic fluid culture. Immediately, intravenous liposomal amphotericin B was administered but the clinical condition rapidly deteriorated and the patient expired despite treatment.
authors.affiliation: Department of Pediatrics, Taichung Veterans General Hospital, Chung Shan Medical University, Taichung, Taiwan.
authors.forename: Wen-Ya
authors.initials: WY
authors.lastname: Lin
authors.forename: Te-Kau
authors.initials: TK
authors.lastname: Chang
authors.forename: Chia-Man
authors.initials: CM
authors.lastname: Chou
authors.forename: Chian-Yin
authors.initials: CY
authors.lastname: Shen
authors.forename: Jiaan-Der
authors.initials: JD
authors.lastname: Wang
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D003106:Colon / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents