title: [Management of mesh-related infections].
abstract: Infections of an implanted hernia mesh are a major challenge. The incidence of mesh infections after incisional hernia repair is about 1% for endoscopic techniques and can be more than 15% in open techniques. Intraoperative mesh contamination is considered to be the primary cause. All woven or knitted hernia meshes have recesses where bacteria may adhere and establish colonies. The bacterial spectrum for mesh infection includes skin pathogens, such as Staphylococcus aureus (including MRSA), Streptococcus spp., as well as E. coli, Enterococcus and Mycobacteria. The therapy approach needs to be tailored to the morphological findings and the treatment for uncomplicated phlegmon is broad spectrum antibiotic therapy. If there is encapsulated fluid accumulation, CT-controlled drainage and daily infusion of antiseptics via the drain is a good option. For dermal necrosis, mesh fistula, exposed mesh or enterocutaneous fistula, a precise CT evaluation is necessary to tailor the operation. Vacuum systems are gaining increased acceptance in conditioning the local findings. For most patients the therapeutic concept will be based on individual decisions. If parts of a formerly infected mesh remain in the patient, a lifelong follow-up is necessary.
authors.affiliation: Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie, Universitätsklinikum Würzburg, Oberdürrbacher Strasse 6, Würzburg, Germany. dietz_u@chirurgie.uni-wuerzburg.de
authors.forename: U A
authors.initials: UA
authors.lastname: Dietz
authors.forename: L
authors.initials: L
authors.lastname: Spor
authors.forename: C-T
authors.initials: CT
authors.lastname: Germer
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D001424:Bacterial Infections / Q000473:pathology / Q000628:therapy*; D018441:Biofilms / Q000254:growth & development; D002481:Cellulitis / Q000473:pathology / Q000628:therapy; D004322:Drainage; D006547:Hernia / Q000473:pathology; D059685:Herniorrhaphy; D006801:Humans; D007412:Intestinal Fistula / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008855:Microscopy, Electron, Scanning; D054843:Negative-Pressure Wound Therapy; D012086:Reoperation; D013526:Surgical Mesh / Q000382:microbiology; D013530:Surgical Wound Infection / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local