title: Increased arginine-vasopressin response to hypertonic stimulation and upright posture in idiopathic hyperprolactinemia.
abstract: To evaluate the possible influence of idiopathic hyperprolactinemia on the arginine-vasopressin (AVP) response to osmotic and pressure-volumetric stimuli, 14 idiopathic hyperprolactinemic women and 13 normoprolactinemic women were studied during a hypertonic saline infusion test (0.51M NaCl infusion for 2h) and an orthostatic test (standing upright and maintaining an orthostatic position for 20min). In both experimental conditions, the AVP response was significantly higher in women with idiopathic hyperprolactinemia than in normal normoprolactinemic women. These results indicate that in women hyperprolactinemia influences the AVP response to hyperosmotic and hypovolemic stimuli.
authors.affiliation: Department of Internal Medicine and Biomedical Sciences, University of Parma, Italy. vittorio.coiro@unipr.it
authors.forename: Vittorio
authors.initials: V
authors.lastname: Coiro
authors.forename: Riccardo
authors.initials: R
authors.lastname: Volpi
authors.forename: Simona
authors.initials: S
authors.lastname: Cataldo
authors.forename: Gloria
authors.initials: G
authors.lastname: Saccani-Jotti
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Magotti
authors.forename: Francesca
authors.initials: F
authors.lastname: Russo
authors.forename: Adriano
authors.initials: A
authors.lastname: Stella
authors.forename: Alessandro
authors.initials: A
authors.lastname: Vignali
authors.forename: Paolo
authors.initials: P
authors.lastname: Chiodera
mesh_terms: D000328:Adult; D001127:Arginine Vasopressin / Q000502:physiology*; D005260:Female; D006339:Heart Rate; D006801:Humans; D006966:Hyperprolactinemia / Q000378:metabolism*; D009994:Osmolar Concentration; D011187:Posture / Q000502:physiology*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage*
chemical_list: D012462:Saline Solution, Hypertonic; D001127:Arginine Vasopressin