title: Treatment of bromhidrosis with a glycine-soja sterocomplex topical product.
abstract: OBJECTIVE
  Bromhidrosis is a common problem with a severe negative impact on the patient's social and emotional life. The objective of this open-label study was to evaluate the efficacy and safety of a local product with the main active ingredient of glycine-soja sterocomplex in the treatment of local bromhidrosis.
  
  
  METHODS
  Eighteen patients with axillary bromhidrosis and eight patients with bromhidrosis of the genital area were included. Bromhidrosis was evaluated through a sniff test of a worn garment on a four-point scale. Patients applied a glycine-soja sterocomplex topical agent twice daily on the affected areas for 15 days and bromhidrosis was evaluated again.
  
  
  RESULTS
  Subjective mean level of bromhidrosis at baseline was 3.50 ± 0.50 and after treatment 1.53 ± 0.51. Mean impact on quality of life at baseline was 3.30 ± 0.48 and after treatment 1.30 ± 0.49. Investigators objective evaluation revealed an improvement in intensity of odor from 3.23 ± 0.83 to 1.53 ± 0.53 and in acceptability of odor from 3.1 ± 1.01 to 1.65 ± 0.76.
  
  
  CONCLUSIONS
  The glycine-soja sterocomplex topical agent shows encouraging improvement on both the intensity and quality of odor in patients with bromhidrosis and has a profound improvement on the patients' quality of life without any side effects.
authors.affiliation: Hyperhidrosis clinic, Andreas Sygros Hospital, Athens, Greece. stamgreg@yahoo.gr
authors.forename: Stamatis
authors.initials: S
authors.lastname: Gregoriou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Rigopoulos
authors.forename: Zoe
authors.initials: Z
authors.lastname: Chiolou
authors.forename: Dafni
authors.initials: D
authors.lastname: Papafragkaki
authors.forename: Michalis
authors.initials: M
authors.lastname: Makris
authors.forename: George
authors.initials: G
authors.lastname: Kontochristopoulos
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001365:Axilla / Q000503:physiopathology; D005260:Female; D005835:Genitalia / Q000503:physiopathology; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009812:Odorants / Q000517:prevention & control*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D011788:Quality of Life; D013025:Glycine max; D013542:Sweat / Q000382:microbiology; D055815:Young Adult
chemical_list: D010936:Plant Extracts