title: Echographic evidence of regression of a periocular infantile capillary hemangioma treated with systemic propranolol.
abstract: This article documents quantitative changes in the size of a periocular capillary hemangioma using sequential echographic testing in a patient receiving off-label treatment with systemic propranolol therapy. The patient presented at 7 weeks old with a right periocular capillary hemangioma. Systemic propranolol therapy was elected. Diagnostic B-scan and quantitative A-scan echography documented the lesion size at presentation as 22.3 mm in greatest dimension. The tumor decreased in size to 20.0 mm after 2½ weeks of treatment and 16.0 mm after 6½ weeks of treatment. No adverse side effects have been noted. Echography is an excellent modality for documenting the regression of periocular capillary hemangiomas during treatment with systemic propranolol.
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA. Swester2@med.miami.edu
authors.forename: Sara Tullis
authors.initials: ST
authors.lastname: Wester
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Johnson
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D005260:Female; D018324:Hemangioma, Capillary / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D056687:Off-Label Use; D011433:Propranolol / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol