title: [The therapeutic contribution of proteomic approaches in cancers].
abstract: Up to now, there are no protein tumor markers with a specificity and sensitivity sufficient to have a utility in prognosis and early diagnosis of cancer. Recent advances in proteomics approaches have led to the identification of novel tumor markers of cancer that may have a utility in screening strategies and treatment. The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins.
authors.affiliation: Laboratoire d'immuno-oncologie moléculaire, faculté de médecine de Monastir, 5019 Monastir, Tunisie. bechrhamrita@yahoo.fr
authors.forename: B
authors.initials: B
authors.lastname: Hamrita
authors.forename: H B
authors.initials: HB
authors.lastname: Nasr
authors.forename: M
authors.initials: M
authors.lastname: Kabbage
authors.forename: P
authors.initials: P
authors.lastname: Hamann
authors.forename: L
authors.initials: L
authors.lastname: Kuhn
authors.forename: C
authors.initials: C
authors.lastname: Guillier
authors.forename: S
authors.initials: S
authors.lastname: Remadi
authors.forename: A
authors.initials: A
authors.lastname: Chaieb
authors.forename: H
authors.initials: H
authors.lastname: Khairi
authors.forename: L
authors.initials: L
authors.lastname: Chouchane
authors.forename: K
authors.initials: K
authors.lastname: Chahed
mesh_terms: D001323:Autoantibodies; D014408:Biomarkers, Tumor / Q000032:analysis / Q000097:blood; D006801:Humans; D009363:Neoplasm Proteins / Q000032:analysis; D009369:Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis; D040901:Proteomics; D012680:Sensitivity and Specificity
chemical_list: D001323:Autoantibodies; D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins