title: New Delhi metallo-β-lactamase (NDM-1)-producing Klebsiella pneumoniae: case report and laboratory detection strategies.
abstract: The spread of antimicrobial resistance among Enterobacteriaceae is a significant clinical threat. We report the first case of an Enterobacteriaceae strain harboring the NDM-1 metallo-β-lactamase in a pediatric patient in the United States. We describe strategies for the detection of this novel resistance mechanism encountered in an isolate of Klebsiella pneumoniae.
authors.affiliation: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave., Brentwood Annex, Los Angeles, CA 90095-1732, USA.
authors.forename: A Brian
authors.initials: AB
authors.lastname: Mochon
authors.forename: Omai B
authors.initials: OB
authors.lastname: Garner
authors.forename: Janet A
authors.initials: JA
authors.lastname: Hindler
authors.forename: Paul
authors.initials: P
authors.lastname: Krogstad
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Ward
authors.forename: Michael A
authors.initials: MA
authors.lastname: Lewinski
authors.forename: James K
authors.initials: JK
authors.lastname: Rasheed
authors.forename: Karen F
authors.initials: KF
authors.lastname: Anderson
authors.forename: Brandi M
authors.initials: BM
authors.lastname: Limbago
authors.forename: Romney M
authors.initials: RM
authors.lastname: Humphries
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006801:Humans; D007223:Infant; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000302:isolation & purification*; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D014481:United States; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1