title: Treatment strategies in metastatic renal cell carcinoma : cytokines, vaccines, and gene therapy.
abstract: In recent years, the incidence of renal cell carcinoma (RCC) has increased dramatically (54% from 1975 to 1990), and in 1996, approx 30,000 new cases were diagnosed in the United States (1). In the same year, an estimated 12,000 RCC-related deaths occurred in the United States. The increased incidence of RCC in recent years may be linked to certain risk factors such as smoking, obesity, high-protein diets, and hypertension (2).
authors.affiliation: Department of Urology, University Hospital St. Radboud, Nijmegen, The Netherlands.
authors.forename: P F
authors.initials: PF
authors.lastname: Mulders