title: Perioperative risk factors for pulmonary complications after liver transplantation.
abstract: Using monofactorial and multivariate logistic regression analyses, the correlation of perioperative risk factors with postoperative pulmonary complications (PPCs) within 1 month after orthotopic liver transplantation (OLT) was investigated. Data on 107 patients (median age 46.8 years, 72% male) with end-stage liver disease who received OLT were retrospectively analysed. The incidence of PPCs was 60.7%. Overall mortality was 13.1% and pulmonary causes accounted for 85.7% of deaths. Mortality was 18.5% and 4.8% for patients with and without pulmonary complications, respectively. Independent risk factors for PPCs were a preoperative model for end-stage liver disease (MELD) score > or =25, intraoperative fluid transfusion volume > 10 1 and intraoperative blood transfusion volume > 4 l. A fluid balance of < or = -300 ml for > or =2 days of the first 3 days after surgery was protective. Other variables studied did not predict PPCs. It was concluded that improving the patient's preoperative medical condition, restricting intraoperative transfusion volumes and maintaining a negative fluid balance in the first 3 days after operation may decrease PPCs.
authors.affiliation: Fuzong Clinical College, Fujian Medical University, Fuzhou, Fujian Province, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Lin
authors.forename: Z S
authors.initials: ZS
authors.lastname: Cai
authors.forename: Y
authors.initials: Y
authors.lastname: Jiang
authors.forename: L Z
authors.initials: LZ
authors.lastname: Lü
authors.forename: X J
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Q C
authors.initials: QC
authors.lastname: Cai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001803:Blood Transfusion; D005260:Female; D006801:Humans; D015994:Incidence; D008107:Liver Diseases / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects*; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D059035:Perioperative Period; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult