title: [Colonic malacoplakia treated with sulfamethizole and trimethoprim].
abstract: We report a case of colonic malacoplakia in a 78-year-old woman, developed following short-term treatment with prednisolone. Clinically, the patient presented with diarrhoea (up to ten times a day) and malaise. Laboratory tests revealed severe anaemia and elevated inflammatory parameters. Colonoscopy showed macroscopic yellowish nodular changes throughout the colon. Biopsies were diagnostic for malacoplakia and exhibited moderate growth of Escherichia faecium and ciprofloxacin-resistant Escherichia coli. The condition resolved during three months of antibiotic treatment with sulfamethizole and trimethoprim.
authors.affiliation: Medicinsk Afdeling, Amager Hospital, Denmark. mch@dadlnet.dk
authors.forename: Mikkel
authors.initials: M
authors.lastname: Christensen
authors.forename: Svend
authors.initials: S
authors.lastname: Knuhtsen
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Knudsen
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D044684:Colon, Transverse / Q000382:microbiology / Q000473:pathology; D003108:Colonic Diseases / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D003113:Colonoscopy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008287:Malacoplakia / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D013419:Sulfamethizole / Q000627:therapeutic use*; D016896:Treatment Outcome; D014295:Trimethoprim / Q000627:therapeutic use*
chemical_list: D000890:Anti-Infective Agents; D013419:Sulfamethizole; D014295:Trimethoprim