title: Effect of Lactobacillus pentosus S-PT84 ingestion on IFN-α production from plasmacytoid dendritic cells by virus stimulation.
abstract: We investigated the effect of ingesting Lactobacillus pentosus S-PT84 on the interferon-α (IFN-α) production from splenocytes and plasmacytoid dendritic cells by virus stimulation. IFN-α production by the Lactobacillus pentosus S-PT84 ingestion group was significantly greater under the virus-infected condition than that by the control group. Lactobacillus pentosus S-PT84 could enhance the production of IFN-α which is known as an important cytokine for preventing virus infection. It may therefore become a prophylactic tool against such virus infection.
authors.affiliation: Institute for Health Care Science, Suntory Wellness Limited, Osaka, Japan. Takayuki_Izumo@suntory.co.jp
authors.forename: Takayuki
authors.initials: T
authors.lastname: Izumo
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Maekawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ida
authors.forename: Atsuko
authors.initials: A
authors.lastname: Kishi
authors.forename: Kaoru
authors.initials: K
authors.lastname: Akatani
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Kiso
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000378:metabolism* / Q000821:virology*; D004435:Eating; D016898:Interferon-alpha / Q000096:biosynthesis* / Q000494:pharmacology; D007778:Lactobacillus / Q000502:physiology*; D008297:Male; D051379:Mice; D010253:Respirovirus Infections / Q000517:prevention & control; D029082:Sendai virus / Q000502:physiology*
chemical_list: D016898:Interferon-alpha