title: High-fidelity determination of security threats via a Boolean biocatalytic cascade.
abstract: The ability to assess diverse security threats using a biochemical logic network system is demonstrated. The new biocatalytic cascade, emulating a NOR logic gate, is able to identify the presence of explosive compounds and nerve agents by providing a simple and rapid 'YES'/'NO' alert.
authors.affiliation: Department of Nanoengineering, University of California San Diego, La Jolla, California 92093, USA.
authors.forename: Min-Chieh
authors.initials: MC
authors.lastname: Chuang
authors.forename: Joshua Ray
authors.initials: JR
authors.lastname: Windmiller
authors.forename: Padmanabhan
authors.initials: P
authors.lastname: Santhosh
authors.forename: Gabriela
authors.initials: G
authors.lastname: Valdés Ramírez
authors.forename: Evgeny
authors.initials: E
authors.lastname: Katz
authors.forename: Joseph
authors.initials: J
authors.lastname: Wang
mesh_terms: D055162:Biocatalysis; D004136:Dinitrobenzenes / Q000032:analysis / Q000737:chemistry; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D053834:Explosive Agents / Q000032:analysis* / Q000737:chemistry; D008128:Logic; D008743:Methyl Parathion / Q000032:analysis / Q000737:chemistry; D010261:Paraoxon / Q000737:chemistry; D014303:Trinitrotoluene / Q000737:chemistry
chemical_list: D004136:Dinitrobenzenes; D004798:Enzymes; D053834:Explosive Agents; D014303:Trinitrotoluene; D008743:Methyl Parathion; C016403:2,4-dinitrotoluene; D010261:Paraoxon