title: Epigenetic inheritance: uncontested?
abstract: "Epigenetics" is currently defined as "the inheritance of variation (-genetics) above and beyond (epi-) changes in the DNA sequence". Despite the fact that histones are believed to carry important epigenetic information, little is known about the molecular mechanisms of the inheritance of histone-based epigenetic information, including histone modifications and histone variants. Here we review recent progress and discuss potential models for the mitotic inheritance of histone modifications-based epigenetic information.
authors.affiliation: National Institute of Biological Sciences, Beijing 102206, China. zhubing@nibs.ac.cn
authors.forename: Bing
authors.initials: B
authors.lastname: Zhu
authors.forename: Danny
authors.initials: D
authors.lastname: Reinberg
mesh_terms: D044127:Epigenesis, Genetic; D006657:Histones / Q000235:genetics / Q000378:metabolism; D008745:Methylation; D008938:Mitosis; D008957:Models, Genetic
chemical_list: D006657:Histones