title: [PCR-SSCP analysis of nm23 gene mutation in non-small cell lung cancer].
abstract: BACKGROUND
  To investigate the role of nm23 gene mutation in human non small cell lung cancer (NSCLC).
  
  
  METHODS
  The mutation of nm23 gene was detected in 53 primary NSCLC tissues and 5 cases of other pulmonary benign or malignant disease tissues by PCR SSCP.
  
  
  RESULTS
  No mutation of nm23 gene was found in all 58 specimens.
  
  
  CONCLUSIONS
  The mutation of the nm23 gene may not effectively forebode the aggressiveness and metastatic potential of NSCLC.
authors.affiliation: Department of Thoracic Surgery, Shanghai Pneumology Hospital, Shanghai 200433, P.R.China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Wang
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Chen
authors.forename: Wen
authors.initials: W
authors.lastname: Gao
authors.forename: Jiaan
authors.initials: J
authors.lastname: Ding
authors.forename: Xianghua
authors.initials: X
authors.lastname: Yi