title: Jaw-opening dystonia: Quality of life after botulinum toxin injections.
abstract: The objective of this study was to investigate quality-of-life outcomes in patients with jaw-opening oromandibular dystonia who had received treatment with botulinum neurotoxin injections. The Glasgow Benefit Inventory (GBI) was used as a post-intervention questionnaire to measure patient benefit. Twenty-five questionnaires were sent to patients. Of the 12 patients who returned the form (48% response rate), the mean scores for the general GBI subscore (p = 0.001), the social support GBI subscore (p = 0.031), and the physical health GBI subscore (p = 0.002) demonstrated statistically significant benefit from the injections. No scores demonstrated a negative impact. Botulinum neurotoxin injections were demonstrated to benefit the quality of life in patients suffering from jaw-opening oromandibular dystonia.
authors.affiliation: Department of Otolaryngology, Loyola University Medical Center, 3633 West Lake Ave., Suite 300, Glenview, IL 60026, USA. scharous@comcast.net
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Charous
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Comella
authors.forename: Wenqing
authors.initials: W
authors.lastname: Fan
mesh_terms: D000328:Adult; D000368:Aged; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use*; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004421:Dystonia / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000188:drug therapy* / Q000523:psychology; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins