title: Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex.
abstract: The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon the addition of Angeli's salt (Na(2)N(2)O(3)) was also applied to bioimaging in A375 cells.
authors.affiliation: State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, Nanjing 210009, People's Republic of China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Ke
authors.initials: K
authors.lastname: Liu
authors.forename: Ju-Ying
authors.initials: JY
authors.lastname: Li
authors.forename: Yuan
authors.initials: Y
authors.lastname: Fang
authors.forename: Tian-Chu
authors.initials: TC
authors.lastname: Zhao
authors.forename: Cheng
authors.initials: C
authors.lastname: Yao
mesh_terms: D045744:Cell Line, Tumor; D003300:Copper / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D009573:Nitrites / Q000737:chemistry; D009589:Nitrogen Oxides / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D009573:Nitrites; D009589:Nitrogen Oxides; D009942:Organometallic Compounds; C021229:oxyhyponitrite; D003300:Copper; C030123:coumarin; C039900:nitroxyl