title: Seizure and encephalopathy associated with thyroid storm in children.
abstract: Thyroid storm with seizures is very rare in children. The authors report 3 children with thyroid storm who had a seizure in the absence of a history of neurologic disease. Acute medical management with propylthiouracil, Lugol's iodine solution, hydrocortisone, and propranolol led to a complete resolution of the symptoms. Patients with thyroid storm may be predisposed to the development of neuropsychiatric change. Early recognition and treatment of thyroid storm are essential to reduce morbidity and mortality from this disorder.
authors.affiliation: Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.
authors.forename: Hae Sang
authors.initials: HS
authors.lastname: Lee
authors.forename: Jin Soon
authors.initials: JS
authors.lastname: Hwang
mesh_terms: D000293:Adolescent; D013956:Antithyroid Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000188:drug therapy; D065768:Lennox Gastaut Syndrome; D008297:Male; D012640:Seizures / Q000150:complications* / Q000188:drug therapy; D013036:Spasms, Infantile / Q000150:complications / Q000188:drug therapy; D013958:Thyroid Crisis / Q000150:complications* / Q000188:drug therapy; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013956:Antithyroid Agents; D013963:Thyroid Hormones