title: Recording force events of single quantum-dot endocytosis.
abstract: We applied force spectroscopy based on atomic force microscope (AFM) to demonstrate the possibility of measuring the interaction force between single quantum-dots (QDs) and living cells at single particle level under native conditions. In the force-distance cycle, we recorded the events of cellular uptake of single QDs and single QD detachment from the cell.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Shan
authors.forename: Xian
authors.initials: X
authors.lastname: Hao
authors.forename: Xin
authors.initials: X
authors.lastname: Shang
authors.forename: Mingjun
authors.initials: M
authors.lastname: Cai
authors.forename: Junguang
authors.initials: J
authors.lastname: Jiang
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Tang
authors.forename: Hongda
authors.initials: H
authors.lastname: Wang
mesh_terms: D002470:Cell Survival; D004705:Endocytosis; D006367:HeLa Cells; D006801:Humans; D018625:Microscopy, Atomic Force; D045663:Quantum Dots