title: Calcifying odontogenic cysts associated with odontomas: confocal laser scanning microscopy analysis of 13 cases.
abstract: The so-called calcifying odontogenic cyst (COC) represents a heterogeneous group of lesions that exhibit a variety of clinico-pathologic features. It is an uncommon lesion and represents less than 2% of all odontogenic cysts and tumors. Recently, these lesions have been reclassified as calcifying cystic odontogenic tumors (CCOT), according to the new World Health Organization (WHO) classification. CCOT are frequently found in association with, or containing areas histologically identical to, various types of odontogenic tumors, such as complex/compound odontomas. This work analyzed clinical and histological data deriving from 13 patients affected by CCOT associated with odontomas. Moreover, a confocal laser scanning microscope (CLSM) analysis was undertaken to further a better understanding of the nature of this peculiar lesion.
authors.affiliation: Department of Odontostomatology, Orthodontics and Surgical Disciplines, University of Naples (SUN), Naples, Italy. alucchese@hotmail.com
authors.forename: Alberta
authors.initials: A
authors.lastname: Lucchese
authors.forename: Massimo
authors.initials: M
authors.lastname: Petruzzi
authors.forename: Michele
authors.initials: M
authors.lastname: Scivetti
authors.forename: Giovanni Pietro
authors.initials: GP
authors.lastname: Pilolli
authors.forename: Maria Beatrice
authors.initials: MB
authors.lastname: Di Bisceglie
authors.forename: Vito
authors.initials: V
authors.lastname: Crincoli
authors.forename: Carlo
authors.initials: C
authors.lastname: Lajolo
authors.forename: Michele
authors.initials: M
authors.lastname: Giuliani
authors.forename: Michele
authors.initials: M
authors.lastname: Calabro
authors.forename: Agostino
authors.initials: A
authors.lastname: Guida
authors.forename: Luigi
authors.initials: L
authors.lastname: Laino
authors.forename: Rosario
authors.initials: R
authors.lastname: Serpico
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Favia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D018333:Odontogenic Cyst, Calcifying / Q000150:complications / Q000473:pathology*; D009810:Odontoma / Q000150:complications / Q000473:pathology*; D014071:Tooth Abnormalities / Q000150:complications / Q000473:pathology*; D055815:Young Adult