title: Neurological outcome in patients with traumatic brain injury and its relationship with computed tomography patterns of traumatic subarachnoid hemorrhage.
abstract: OBJECTIVE
  Traumatic subarachnoid hemorrhage (SAH) is a poor prognostic factor for traumatic brain injury. The authors aimed to further investigate neurological outcome among head injury patients by examining the prognostic values of CT patterns of traumatic SAH, in particular, the thickness and distribution.
  
  
  METHODS
  The study was conducted using a database in a regional trauma center in Hong Kong. Data had been prospectively collected in consecutive trauma patients between January 2006 and December 2008. Patients included in the study had significant head injury (as defined by a head Abbreviated Injury Scale [AIS] score of 2 or more) with traumatic SAH according to admission CT.
  
  
  RESULTS
  Over the 36-month period, 661 patients with significant head injury were admitted to the Prince of Wales Hospital in Hong Kong. Two hundred fourteen patients (32%) had traumatic SAH on admission CT. The mortality rate was significantly greater and a 6-month unfavorable outcome was significantly more frequent in patients with traumatic SAH. Multivariate analysis showed that the maximum thickness (mm) of traumatic SAH was independently associated with neurological outcome (OR 0.8, 95% CI 0.7-0.9) and death (OR 1.3, 95% CI 1.2-1.5) but not with the extent or location of hemorrhage.
  
  
  CONCLUSIONS
  Maximum thickness of traumatic SAH was a strong independent prognostic factor for death and clinical outcome. Anatomical distribution per se did not affect clinical outcome.
authors.affiliation: Division of Neurosurgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. georgewong@surgery.cuhk.edu.hk
authors.forename: George K C
authors.initials: GK
authors.lastname: Wong
authors.forename: Janice H H
authors.initials: JH
authors.lastname: Yeung
authors.forename: Colin A
authors.initials: CA
authors.lastname: Graham
authors.forename: Xian-lun
authors.initials: XL
authors.lastname: Zhu
authors.forename: Timothy H
authors.initials: TH
authors.lastname: Rainer
authors.forename: Wai S
authors.initials: WS
authors.lastname: Poon
mesh_terms: D015998:Abbreviated Injury Scale; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000150:complications / Q000000981:diagnostic imaging* / Q000401:mortality*; D016208:Databases, Factual; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D011859:Radiography; D020206:Subarachnoid Hemorrhage, Traumatic / Q000150:complications / Q000000981:diagnostic imaging* / Q000401:mortality*; D014193:Trauma Centers; D016896:Treatment Outcome