title: Polymerase trafficking: A role for transcription factors in preventing replication fork arrest.
abstract: Replication forks and transcription complexes often collide, which can result in mutagenesis and chromosomal rearrangements. Recent studies of E. coli demonstrate a role for transcription factors in reducing conflicts between replication and transcription. These findings suggest that transcription regulators preserve genome integrity by preventing replication fork arrest.
authors.affiliation: The Rockefeller University; Howard Hughes Medical Institute; New York, NY USA.
authors.forename: Richard T
authors.initials: RT
authors.lastname: Pomerantz
authors.forename: Mike
authors.initials: M
authors.lastname: O'Donnell