title: Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy.
abstract: OBJECTIVE
  To report a rare case of choroidal metastasis from hepatocellular carcinoma.
  
  
  METHODS
  A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 × 14 × 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC.
  
  
  RESULTS
  The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented.
  
  
  CONCLUSIONS
  HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.
authors.affiliation: Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Suite 1440, 840 Walnut Street, Philadelphia, PA 19107, USA.
authors.forename: Lalkrushna
authors.initials: L
authors.lastname: Malaviya
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Kiran
authors.initials: K
authors.lastname: Turaka
authors.forename: Hormoz
authors.initials: H
authors.lastname: Ehya
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D044963:Biopsy, Fine-Needle; D001918:Brachytherapy; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary*; D002830:Choroid Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D014463:Ultrasonography; D014792:Visual Acuity
chemical_list: D007457:Iodine Radioisotopes