title: Mitomycin C therapy for corneal intraepithelial neoplasia masquerading as limbal stem cell deficiency with recurrent epithelial defect.
abstract: Diagnosis of corneal intraepithelial neoplasia was missed in a patient who presented with recurrent large epithelial defects with pannus. The patient was eventually diagnosed and successfully treated with topical mitomycin C. Mitomycin C may be preferable to surgery in lesions with extensive corneal involvement. Impression cytology should be used for early diagnosis in suspicious lesions.
authors.affiliation: Gokhale Eye Hospital and Eyebank, India. nikgokhale@yahoo.com
authors.forename: Nikhil S
authors.initials: NS
authors.lastname: Gokhale
mesh_terms: D000287:Administration, Topical; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D002278:Carcinoma in Situ / Q000188:drug therapy* / Q000473:pathology; D003316:Corneal Diseases / Q000188:drug therapy* / Q000473:pathology; D003937:Diagnosis, Differential; D004334:Drug Administration Schedule; D005134:Eye Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D013234:Stem Cells / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin