title: Correlation functions for Elekta aSi EPIDs used as transit dosimeter for open fields.
abstract: In-vivo dosimetry techniques are currently being applied only by a few Centers because they require time-consuming implementation measurements, and workload for detector positioning and data analysis. The transit in-vivo dosimetry performed by the electronic portal imaging device (EPID) avoids the problem of solid-state detector positioning on the patient. Moreover, the dosimetric characterization of the recent Elekta aSi EPIDs in terms of signal stability and linearity make these detectors useful for the transit in-vivo dosimetry with 6, 10 and 15 MV photon beams. However, the implementation of the EPID transit dosimetry requires several measurements. Recently, the present authors have developed an in-vivo dosimetry method for 3D CRT based on correlation functions defined by the ratios between the transit signal, st (w,L), by the EPID and the phantom midplane dose, Dm(w,L), at the source to axis distance (SAD) as a function of the phantom thickness, w, and the square field dimensions, L. When the phantom midplane was positioned at distance, d, from the SAD, the ratios st(w,L)/s't(d,w,L) were used to take into account the variation of the scattered photon contributions on the EPID as a function of d and L.The aim of this paper is the implementation of a procedure that uses generalized correlation functions obtained by nine Elekta Precise linac beams. The procedure can be used by other Elekta Precise linacs equipped with the same aSi EPIDs, assuming the stabilities of the beam output factors and the EPID signals. The procedure here reported avoids measurements in solid water equivalent phantoms needed to implement the in-vivo dosimetry method in the radiotherapy department. A tolerance level ranging between ± 5% and ± 6% (depending on the type of tumor) was estimated for the comparison between the reconstructed isocenter dose, Diso, and the computed dose, Diso,TPS, by the treatment planning system (TPS).
authors.affiliation: U.O di Fisica Sanitaria, Centro di Ricerca e Formazione ad Alta Tecnologia nelle Scienze Biomediche, Università Cattolica del Sacro Cuore, Campobasso, Italy. a.piermattei@rm.unicatt.it
authors.forename: Savino
authors.initials: S
authors.lastname: Cilla
authors.forename: Andrea
authors.initials: A
authors.lastname: Fidanzio
authors.forename: Francesca
authors.initials: F
authors.lastname: Greco
authors.forename: Domenico
authors.initials: D
authors.lastname: Sabatino
authors.forename: Aniello
authors.initials: A
authors.lastname: Russo
authors.forename: Laura
authors.initials: L
authors.lastname: Gargiulo
authors.forename: Luigi
authors.initials: L
authors.lastname: Azario
authors.forename: Angelo
authors.initials: A
authors.lastname: Piermattei
mesh_terms: D002138:Calibration; D055615:Electrical Equipment and Supplies; D006801:Humans; D021621:Imaging, Three-Dimensional; D009369:Neoplasms / Q000532:radiotherapy*; D019047:Phantoms, Imaging; D017785:Photons; D011786:Quality Control; D011836:Radiation Tolerance; D011874:Radiometry / Q000295:instrumentation / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods*