title: Bupivacaine injection during midurethral sling and postoperative pain: a randomized controlled trial.
abstract: OBJECTIVE
  The aim of this study was to investigate the impact of retropubic injection of 0.125% bupivacaine during midurethral sling placement on postoperative pain.
  
  
  METHODS
  A randomized, double-blind trial of 42 women undergoing midurethral sling for stress incontinence was conducted. The intervention group received an injection of 0.125% bupivacaine in the retropubic space prior to midurethral sling placement, while the control group received no injection. Pain scores were recorded via a 10-cm visual analog scale at 2, 6, and 24 h postoperatively.
  
  
  RESULTS
  Pain scores were lower in the bupivacaine group compared to the control group at 2 h (1.9 versus 2.6, p = 0.05). Mean pain scores were similar at all other time points (all p > 0.45). Participants in both groups used similar amounts of pain medication in the hospital, except that patients in the bupivacaine group used more PO non-steroidal anti-inflammatory drugs (p = 0.047).
  
  
  CONCLUSIONS
  Retropubic injection of 0.125% bupivacaine at the time of midurethral sling placement decreases short-term postoperative pain.
authors.affiliation: Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, 3032 Old Clinic Building, Campus Box 7570, Chapel Hill, NC 27599-7570, USA.
authors.forename: Gena C
authors.initials: GC
authors.lastname: Dunivan
authors.forename: Brent A
authors.initials: BA
authors.lastname: Parnell
authors.forename: AnnaMarie
authors.initials: A
authors.lastname: Connolly
authors.forename: Mary L
authors.initials: ML
authors.lastname: Jannelli
authors.forename: Bethany Jablonski
authors.initials: BJ
authors.lastname: Horton
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Geller
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control*; D053825:Suburethral Slings; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D013520:Urologic Surgical Procedures
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine