title: An algorithm based on OmniView technology to reconstruct sagittal and coronal planes of the fetal brain from volume datasets acquired by three-dimensional ultrasound.
abstract: OBJECTIVE
  To describe a novel algorithm, based on the new display technology 'OmniView', developed to visualize diagnostic sagittal and coronal planes of the fetal brain from volumes obtained by three-dimensional (3D) ultrasonography.
  
  
  METHODS
  We developed an algorithm to image standard neurosonographic planes by drawing dissecting lines through the axial transventricular view of 3D volume datasets acquired transabdominally. The algorithm was tested on 106 normal fetuses at 18-24 weeks of gestation and the visualization rates of brain diagnostic planes were evaluated by two independent reviewers. The algorithm was also applied to nine cases with proven brain defects.
  
  
  RESULTS
  The two reviewers, using the algorithm on normal fetuses, found satisfactory images with visualization rates ranging between 71.7% and 96.2% for sagittal planes and between 76.4% and 90.6% for coronal planes. The agreement rate between the two reviewers, as expressed by Cohen's kappa coefficient, was > 0.93 for sagittal planes and > 0.89 for coronal planes. All nine abnormal volumes were identified by a single observer from among a series including normal brains, and eight of these nine cases were diagnosed correctly.
  
  
  CONCLUSIONS
  This novel algorithm can be used to visualize standard sagittal and coronal planes in the fetal brain. This approach may simplify the examination of the fetal brain and reduce dependency of success on operator skill.
authors.affiliation: Fetal Medicine Center Genoma, Rome, Italy. giuseppe.rizzo@uniroma2.it
authors.forename: G
authors.initials: G
authors.lastname: Rizzo
authors.forename: A
authors.initials: A
authors.lastname: Capponi
authors.forename: M E
authors.initials: ME
authors.lastname: Pietrolucci
authors.forename: A
authors.initials: A
authors.lastname: Capece
authors.forename: E
authors.initials: E
authors.lastname: Aiello
authors.forename: S
authors.initials: S
authors.lastname: Mammarella
authors.forename: D
authors.initials: D
authors.lastname: Arduini
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology / Q000196:embryology / Q000473:pathology*; D002493:Central Nervous System Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008875:Middle Aged; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal / Q000379:methods*; D055815:Young Adult