title: Postprandial lipemia in children and adolescents.
abstract: Atherosclerosis is a result of a lifelong process that has its origins in childhood. Data in adults suggest that impaired postprandial lipoprotein metabolism may contribute to, or be a marker of, the development and progression of atherosclerosis. After an 8-year follow up period, the Bogalusa Heart Study showed that children with low high density lipoprotein cholesterol, high triglyceride levels and high body mass index had a notably increased occurrence of dyslipidemia as adults. A significantly greater postprandial response of triglycerides in children with elevated fasting triglyceride levels was reported. It is well known that dietary fat is associated with higher plasma triglyceride levels. It is not clear if postprandial lipemia should be evaluated in children and adolescents. However, in special situations this may help determine the underlying lipid disorder. This review discusses the current status in this field.
authors.affiliation: Cardiology Department, Onassis Cardiac Surgery Center, 356 Sygrou Avenue, 17674 Athens, Greece. genovefa@kolovou.com
authors.forename: Genovefa D
authors.initials: GD
authors.lastname: Kolovou
authors.forename: Helen
authors.initials: H
authors.lastname: Bilianou
authors.forename: Dimitri P
authors.initials: DP
authors.lastname: Mikhailidis
mesh_terms: D000293:Adolescent; D000367:Age Factors; D050197:Atherosclerosis / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D008076:Cholesterol, HDL / Q000097:blood; D004041:Dietary Fats / Q000009:adverse effects; D018450:Disease Progression; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications* / Q000175:diagnosis; D015228:Hypertriglyceridemia / Q000150:complications; D008074:Lipoproteins / Q000097:blood; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D004041:Dietary Fats; D008074:Lipoproteins; D014280:Triglycerides