title: Spectrum of orbital and ocular adnexal lesions: an analysis of 389 cases diagnosed by fine needle aspiration cytology.
abstract: The aim of the present study was to evaluate the scope and the limitations of fine needle aspiration cytology (FNAC) in orbital and ocular adnexal lesions. This study was a retrospective audit of 389 cases of orbital and ocular adnexal lesions subjected to FNAC over a period of 12 years (1998-2009). The cyto-smears were reviewed and the lesions were categorized under different diagnostic categories in adult and pediatric population. Three hundred and one adult patients (age ≥15 years) and 88 pediatric patients (age ≤14 years) constituted the study group. In the adult population, there were 23.3% cases of infectious and lymphoproliferative lesions and 12.6% of benign cysts. In the pediatric population, 18.2% cases had infectious and lymphoproliferative lesions and 8% had benign cysts. Various benign tumors (9.6% in adults) included pleomorphic adenoma, meningioma, and schwannoma. Benign vascular tumors predominated in the pediatric population. A majority of malignant tumors in adults were lymphoreticular malignancies (12.6%); non-Hodgkin's lymphoma being the most common followed by malignant epithelial tumors (10.3%). Nearly 3.6% cases of soft tissue/bone sarcomas and 6.3% of metastatic tumors were seen in adult population. However, most of the orbital tumors in the pediatric population were malignant small blue round cell tumors (33%). FNAC is a cost-effective technique with good diagnostic value in the assessment of ophthalmic lesions, especially when sampling and interpretation are performed by experienced personnel in the light of clinico-radiological information.
authors.affiliation: Department of Cytopathology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. nalini203@rediffmail.com
authors.forename: Nalini
authors.initials: N
authors.lastname: Gupta
authors.forename: Jasleen
authors.initials: J
authors.lastname: Kaur
authors.forename: Arvind
authors.initials: A
authors.lastname: Rajwanshi
authors.forename: Raje
authors.initials: R
authors.lastname: Nijhawan
authors.forename: Radhika
authors.initials: R
authors.lastname: Srinivasan
authors.forename: Pranab
authors.initials: P
authors.lastname: Dey
authors.forename: Usha
authors.initials: U
authors.lastname: Singh
authors.forename: Pankaj
authors.initials: P
authors.lastname: Gupta
mesh_terms: D000293:Adolescent; D000328:Adult; D001230:Aspergillus / Q000302:isolation & purification / Q000472:pathogenicity; D044963:Biopsy, Fine-Needle / Q000379:methods* / Q000592:standards; D002648:Child; D002675:Child, Preschool; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009362:Neoplasm Metastasis / Q000175:diagnosis / Q000473:pathology; D009369:Neoplasms / Q000175:diagnosis; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D055815:Young Adult