title: Protection from avian influenza H5N1 virus infection with antibody-impregnated filters.
abstract: There is worldwide concern over the possibility of a new influenza pandemic originating from the highly pathogenic avian H5N1 influenza viruses. We herein demonstrate that functional air filters impregnated with ostrich antibodies against the hemagglutinin of the H5N1 virus protect chickens from death by H5N1 transmission. These results suggest that the use of ostrich antibody-impregnated filters might be a powerful way to prevent the transmission of H5N1.
authors.affiliation: Life Science Research Laboratories, Research & Development Management Headquarters, Fujifilm Corporation, 577 Ushijima, Kaisei-machi, Ashigarakamigun, Kanagawa 258-8577, Japan.
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Kamiyama
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Adachi
authors.forename: Ekowati
authors.initials: E
authors.lastname: Handharyani
authors.forename: Retno Damajanti
authors.initials: RD
authors.lastname: Soejoedono
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kusano
authors.forename: Marie
authors.initials: M
authors.lastname: Inai
authors.forename: Masaya
authors.initials: M
authors.lastname: Tsukamoto
authors.forename: Seizaburo
authors.initials: S
authors.lastname: Kashiwagi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tsukamoto
mesh_terms: D000391:Air Microbiology; D000818:Animals; D000914:Antibodies, Viral / Q000378:metabolism*; D002645:Chickens; D004203:Disinfection / Q000379:methods*; D005374:Filtration / Q000379:methods*; D053124:Influenza A Virus, H5N1 Subtype / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000517:prevention & control*; D008851:Micropore Filters / Q000821:virology*; D020310:Struthioniformes
chemical_list: D000914:Antibodies, Viral