title: Lung sequestration: a rare cause for pulmonary symptoms in adulthood.
abstract: BACKGROUND
  Lung sequestration is a rare congenital pulmonary disorder and is usually diagnosed in children with recurrent pulmonary infections. Lung sequestrations are not commonly found to be a cause of respiratory symptoms in adults.
  
  
  OBJECTIVE
  It was the aim of this study to show that pulmonary sequestration is rare in advanced age and can be accompanied by severe pulmonary symptoms.
  
  
  METHODS
  We conducted a case series analysis of patient characteristics, symptoms, diagnosis and treatment of 11 adults with a lung sequestration at the Thoraxklinik Heidelberg between 2001 and 2009.
  
  
  RESULTS
  From 2001 to 2009, intralobar lung sequestration was diagnosed and treated in 11 adults aged 19 to 58 years with an average age of 39.9 ± 11.3 years and a male:female distribution of 5:6. In 3 patients (27.3%), the predominant symptom was hemoptysis. Recurrent pulmonary infections occurred in 1 patient (9.1%); pneumonia and lung abscess were detected in 2 patients (18.2%). In 3 cases (27.3%), dry cough was the predominant symptom, and in only 2 cases (18.2%), lung sequestration was asymptomatic. Eight patients (72.7%) were diagnosed by imaging techniques prior to surgery. In 3 cases (27.3%), diagnosis was made intraoperatively and by pathological examination. Surgical intervention included 7 lobectomies (63.6%), 3 wedge resections (27.3%) and 1 (9.1%) segmentectomy.
  
  
  CONCLUSIONS
  Lung sequestration in adults is rare, but it can cause severe pulmonary symptoms. In cases of recurrent pulmonary infections of identical localization or recurrent hemoptysis, lung sequestration should be considered in order for the diagnosis to be made rapidly. Surgical resection is the treatment of choice.
authors.affiliation: Department of Pneumology and Respiratory Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany. Daniela.Gompelmann@thoraxklinik-heidelberg.de
authors.forename: Daniela
authors.initials: D
authors.lastname: Gompelmann
authors.forename: Ralf
authors.initials: R
authors.lastname: Eberhardt
authors.forename: Claus-Peter
authors.initials: CP
authors.lastname: Heussel
authors.forename: Hans
authors.initials: H
authors.lastname: Hoffmann
authors.forename: Hendrik
authors.initials: H
authors.lastname: Dienemann
authors.forename: Maren
authors.initials: M
authors.lastname: Schuhmann
authors.forename: Dittmar
authors.initials: D
authors.lastname: Böckler
authors.forename: Philipp A
authors.initials: PA
authors.lastname: Schnabel
authors.forename: Arne
authors.initials: A
authors.lastname: Warth
authors.forename: Ruben
authors.initials: R
authors.lastname: Lopez-Benitez
authors.forename: Felix J F
authors.initials: FJ
authors.lastname: Herth
mesh_terms: D000328:Adult; D000367:Age Factors; D001998:Bronchopulmonary Sequestration / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006469:Hemoptysis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011014:Pneumonia / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D016896:Treatment Outcome