title: Molecular imaging of cell-based cancer immunotherapy.
abstract: Cell-based cancer immunotherapy represents a new and powerful weapon in the arsenal of anticancer treatments. Non-invasive monitoring of the disposition, migration and destination of therapeutic cells will facilitate the development of cell based therapy. The therapeutic cells can be modified intrinsically by a reporter gene or labeled extrinsically by introducing imaging probes into the cells or on the cell surface before transplant. Various advanced non-invasive molecular imaging techniques are playing important roles in optimizing cellular therapy by tracking cells and monitoring the therapeutic effects of transplanted cells in vivo. This review will summarize the application of multiple molecular imaging modalities in cell-based cancer immunotherapy.
authors.affiliation: Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong 637007, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Magdalena
authors.initials: M
authors.lastname: Swierczewska
authors.forename: Gang
authors.initials: G
authors.lastname: Niu
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zhang
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D000818:Animals; D006801:Humans; D007167:Immunotherapy; D008279:Magnetic Resonance Imaging; D057054:Molecular Imaging; D009369:Neoplasms / Q000628:therapy*; D011877:Radionuclide Imaging