title: Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995-2005).
abstract: OBJECTIVE
  To characterize clinicopathologic features of the most common odontogenic tumors and focal fibrous hyperplasia (FFH) in dogs.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  152 dogs evaluated for oral tumors of possible odontogenic origin at the William R. Pritchard Veterinary Medical Teaching Hospital of the University of California-Davis between 1995 and 2005.
  
  
  METHODS
  Information was collected from records, including dog breed, age, reproductive status, and location of lesion in the oral cavity. Histologic slides pertaining to each dog were reviewed by 3 investigators. Data regarding clinicopathologic features of the 3 most common lesions (canine acanthomatous ameloblastoma [CAA], peripheral odontogenic fibroma [POF], and FFH) were summarized.
  
  
  RESULTS
  152 dogs with odontogenic tumors or FFH were identified. Sixty-eight (45%) dogs had CAA, 47 (31 %) had POF, 24 (16%) had FFH, and 13 (9%) had other odontogenic tumors. Canine acanthomatous ameloblastoma was present most commonly in the rostral aspect of the mandible, with POF and FFH more common in the rostral aspect of the maxilla. Males and females were equally represented among dogs with CAA and FFH. Castrated males were overrepresented among dogs with POF. Golden Retrievers, Akitas, Cocker Spaniels, and Shetland Sheepdogs were overrepresented among dogs with CAA. No breed predisposition was detected for FFH or POF. Dogs with FFH had a greater mean age at initial evaluation than did dogs with CAA or POF.
  
  
  CONCLUSIONS
  CAA, POF, and FFH have distinct clinical patterns that may help clinicians and pathologists identify such lesions more readily.
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616, USA.
authors.forename: Nadine
authors.initials: N
authors.lastname: Fiani
authors.forename: Frank J M
authors.initials: FJ
authors.lastname: Verstraete
authors.forename: Philip H
authors.initials: PH
authors.lastname: Kass
authors.forename: Darren P
authors.initials: DP
authors.lastname: Cox
mesh_terms: D000564:Ameloblastoma / Q000473:pathology / Q000662:veterinary; D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D005350:Fibroma / Q000473:pathology / Q000662:veterinary; D005885:Gingival Hyperplasia / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009808:Odontogenic Tumors / Q000473:pathology / Q000662:veterinary*; D012727:Sex Characteristics