title: Delayed cervicobulbar neuronopathy and myokymia after head and neck radiotherapy for nasopharyngeal carcinoma: a case report.
abstract: BACKGROUND
  Delayed progressive cervicobulbar palsy with secondary lingual, facial, and neck myokymia after radiation therapy to the head and neck is a known but rare event with few reported case descriptions.
  
  
  METHODS
  We report a case with a video description of a young Asian woman who developed progressive dysarthria and dysphagia after approximately 1 year after radiation treatment for nasopharyngeal carcinoma. Her symptoms, clinical, and electromyographic findings are discussed and were felt to be secondary to a cervicobulbar neuronopathy secondary to the previous radiation she received. A brief literature review was performed and pathophysiological mechanisms and treatment options are discussed.
  
  
  CONCLUSIONS
  Delayed progressive cervicobulbar neuronopathy with myokymia is an uncommon complication of radiotherapy for nasopharyngeal carcinoma. Clinicians should be aware of this entity to prevent misdiagnosis with other neuromuscular and nonneuromuscular diseases.
authors.affiliation: Department of Neurology, University of Southern California, Keck School of Medicine, and Presbyterian Intercommunity Hospital Stroke Center, Whittier, CA 90602, USA. rison@usc.edu
authors.forename: Richard A
authors.initials: RA
authors.lastname: Rison
authors.forename: Said R
authors.initials: SR
authors.lastname: Beydoun
mesh_terms: D000328:Adult; D002277:Carcinoma; D003389:Cranial Nerve Diseases / Q000209:etiology*; D003680:Deglutition Disorders / Q000209:etiology; D004401:Dysarthria / Q000209:etiology; D005260:Female; D006801:Humans; D020385:Myokymia / Q000209:etiology* / Q000503:physiopathology; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries / Q000150:complications* / Q000503:physiopathology; D011878:Radiotherapy / Q000009:adverse effects*