title: Enantioselective synthesis of tertiary thiols by intramolecular arylation of lithiated thiocarbamates.
abstract: Lithiation of N-aryl S-α-alkylbenzyl thiocarbamates leads to rearrangement with migration of the N-aryl ring to the anionic centre α to S, a process which generally proceeds with ca. 98% retention of stereochemistry and returns chiral benzylic tertiary thiols in high enantiomeric ratios.
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: MacLellan
authors.forename: Jonathan
authors.initials: J
authors.lastname: Clayden