title: Combining bio- and chemo-catalysis: from enzymes to cells, from petroleum to biomass.
abstract: In the future, biomass will continue to emerge as a viable source of chemicals. The development of new industries that utilize bio-renewables provides opportunities for innovation. For example, bio- and chemo-catalysts can be combined in 'one pot' to prepare chemicals of commercial value. This has been demonstrated using isolated enzymes and whole cells for a variety of chemical transformations. The one-pot approach has been successfully adopted to convert chemicals derived from biomass, and, in our opinion, it has an important role to play in the design of a more sustainable chemical industry. To implement new one-pot bio- and chemo-catalytic processes, issues of incompatibility must be overcome; the strategies for which are discussed in this opinion article.
authors.affiliation: Queen's University Belfast, David Keir Building, Stranmillis Road, Belfast BT9 5AG, UK. a.marr@qub.ac.uk
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Marr
authors.forename: Shifang
authors.initials: S
authors.lastname: Liu
mesh_terms: D018533:Biomass; D001709:Biotechnology / Q000379:methods*; D001711:Biotransformation; D002384:Catalysis; D002621:Chemistry / Q000379:methods*; D004798:Enzymes / Q000378:metabolism*; D010578:Petroleum / Q000378:metabolism
chemical_list: D004798:Enzymes; D010578:Petroleum