title: Unexpected severe hepatotoxicity of ciprofloxacine: two case reports.
abstract: Ciprofloxacin is a fluoroquinolone antibiotic that has a relatively low rate of occurence of adverse side effects. However, increasing evidences suggest that ciprofloxacin may cause unexpected severe liver damage. Especially, the risk of hepatotoxicity is significantly higher in elderly men receiving drug for a long time. In this article, 2 cases of unexpected severe hepatoxicity of ciprofloxacin are presented.
authors.affiliation: Çanakkale Onsekiz Mart University, Medical Faculty, Departmant of Urology, Turkey. cabir1@yahoo.com
authors.forename: Cabir
authors.initials: C
authors.lastname: Alan
authors.forename: Hasan
authors.initials: H
authors.lastname: Koçoğlu
authors.forename: Ahmet Reşit
authors.initials: AR
authors.lastname: Ersay
authors.forename: Yunus
authors.initials: Y
authors.lastname: Ertung
authors.forename: Hasan Anıl
authors.initials: HA
authors.lastname: Kurt
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000890:Anti-Infective Agents / Q000009:adverse effects*; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood / Q000209:etiology* / Q000473:pathology; D002939:Ciprofloxacin / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase