title: [Pediatrics. Fecal calprotectin in children: use and interpretation].
abstract: Fecal calprotectin is a small protein released mainly by neutrophils. It is recognized as a reliable, easy and non-invasive biomarker of gastro-intestinal inflammation. Normal values vary with age, with higher cut-off values during the first year of life (<350 microg/g) than in children (<275 microg/g) or adults (<50 microg/g). Fecal calprotectin can be a useful tool in initial evaluation of recurrent abdominal pain, helping to distinguish between functional gastro-intestinal disorders, where it is normal, and inflammatory bowel disease (IBD). It is not a specific marker of IBD but is increased in other situations of gastro-intestinal inflammation. In patients with IBD, fecal calprotectin is used to monitor treatment response.
authors.affiliation: Unité de gastroentérologie et nutrition pédiatriques, Département médico-chirurgical de pédiatrie, CHUV, 1011 Lausanne.
authors.forename: J
authors.initials: J
authors.lastname: Ezri
authors.forename: A
authors.initials: A
authors.lastname: Nydegger
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002648:Child; D005243:Feces / Q000737:chemistry*; D005767:Gastrointestinal Diseases / Q000175:diagnosis; D006801:Humans; D039841:Leukocyte L1 Antigen Complex / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D039841:Leukocyte L1 Antigen Complex