title: Control of viral replication after cessation of HAART.
abstract: We describe two patients who did not experience a viral rebound after cessation of HAART which was initiated for progressive disease. CD4 T-cell count remained stable in one patient and progressively declined in the other, despite apparent viral control. We failed to identify any immune activation or genetic markers that could offer an explanation for this unusual "secondary controller" status. But their viruses are clearly less fit compared to viruses from rebounders.
authors.affiliation: Virology unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp (ITMA), Antwerp, Belgium. evangulck@itg.be.
authors.forename: Ellen
authors.initials: E
authors.lastname: Van Gulck
authors.forename: Leo
authors.initials: L
authors.lastname: Heyndrickx
authors.forename: Lotte
authors.initials: L
authors.lastname: Bracke
authors.forename: Sandra
authors.initials: S
authors.lastname: Coppens
authors.forename: Eric
authors.initials: E
authors.lastname: Florence
authors.forename: Anne
authors.initials: A
authors.lastname: Buvé
authors.forename: Paul
authors.initials: P
authors.lastname: Lewi
authors.forename: Guido
authors.initials: G
authors.lastname: Vanham