title: Myocbacterium-avium intracellulare associated inflammatory pseudotumor of the anterior nasal cavity.
abstract: In this case report, we describe an unusual case of mycobacterial associated inflammatory pseudotumor that occurred in a patient with a previous history of cocaine abuse. We discuss inflammatory pseudotumor (IPT) in general and emphasize the rare entity where an associated mycobacterial infection is seen. The histogenesis is not yet completely understood. The lesion can pose challenges for practicing pathologists and a misdiagnosis of malignancy can occur at multiple facets. A discussion about the differential diagnosis and clues to make the distinction is presented. In addition to spindle cell proliferation, the presence of a background of mixed inflammatory cell infiltrate and foamy macrophages are clues to make the diagnosis. In the case of mycobacteria associated IPT, Acid Fast Bacilli (AFB) stains will easily highlight the organisms confirming the diagnosis.
authors.affiliation: Department of Pathology and Laboratory Medicine, James H Quillen VA Medical Center, Lamont and Veterans Way, PO Box 4000, Mountain Home, TN 37684, USA.
authors.forename: Sadaf
authors.initials: S
authors.lastname: Ilyas
authors.forename: Dima
authors.initials: D
authors.lastname: Youssef
authors.forename: Humera
authors.initials: H
authors.lastname: Chaudhary
authors.forename: Mousa A
authors.initials: MA
authors.lastname: Al-Abbadi
mesh_terms: D019970:Cocaine-Related Disorders / Q000150:complications; D006104:Granuloma, Plasma Cell / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications; D008297:Male; D008875:Middle Aged; D015270:Mycobacterium avium-intracellulare Infection / Q000150:complications / Q000473:pathology*; D009296:Nasal Cavity / Q000382:microbiology / Q000473:pathology*; D009668:Nose Diseases / Q000150:complications / Q000382:microbiology / Q000473:pathology*