title: Group A streptococcal infections during the seasonal influenza outbreak 2010/11 in South East England.
abstract: We present a series of 19 cases of invasive Group A streptococcal (iGAS) infection reported to the Thames Valley Health Protection Unit from 1 December 2010 to 15 January 2011. Ten patients died and a prodrome of influenza-like illness was reported in 14 cases.Influenza B co-infection was confirmed in four cases,three of which were fatal. Our report provides further evidence that influenza B co-infection with iGAS has the potential to cause significant morbidity and mortality.
authors.affiliation: Thames Valley Health Protection Unit, Health Protection Agency, Chilton, Didcot, Oxfordshire, United Kingdom. jakub.scaber@hpa.org.uk
authors.forename: J
authors.initials: J
authors.lastname: Scaber
authors.forename: S
authors.initials: S
authors.lastname: Saeed
authors.forename: C
authors.initials: C
authors.lastname: Ihekweazu
authors.forename: A
authors.initials: A
authors.lastname: Efstratiou
authors.forename: N
authors.initials: N
authors.lastname: McCarthy
authors.forename: E
authors.initials: E
authors.lastname: O'Moore
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D004196:Disease Outbreaks; D004739:England / Q000453:epidemiology; D005260:Female; D006760:Hospitalization; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D009981:Influenza B virus / Q000302:isolation & purification*; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000150:complications* / Q000401:mortality / Q000628:therapy / Q000821:virology*; D008297:Male; D008875:Middle Aged; D012621:Seasons; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology* / Q000401:mortality / Q000628:therapy; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines