title: Effectiveness of narrow band imaging in patients with oral squamous cell carcinoma after treatment.
abstract: BACKGROUND
  We evaluated the effectiveness of narrow band imaging (NBI) in patients with oral squamous cell carcinoma (OSCC) after treatment.
  
  
  METHODS
  In all, 101 consecutive OSCC patients underwent NBI examination for posttreatment follow-up. Four patients had local recurrence. Twenty-six second primary malignancies were found in 18 patients; 6 patients (33%) had more than 1 lesion. Seventeen lesions (65%) were carcinoma in situ or severe dysplasia. Most of them occurred in the oral cavity (77%).
  
  
  RESULTS
  A higher incidence (18% vs 9%, p = .037) and less-advanced stage (4% vs 37%, p = .0005) of second primary malignancies were found among the NBI group compared with a previous cohort without NBI examination, and fewer patients needed postoperative adjuvant therapy (12% vs 50%, p = .0005).
  
  
  CONCLUSIONS
  NBI is an effective method to identify early lesions in the head and neck area, especially the oral cavity, among patients with OSCC after treatment.
authors.affiliation: Department of Otolaryngology, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan. pychu@vghtpe.gov.tw
authors.forename: Pen-Yuan
authors.initials: PY
authors.lastname: Chu
authors.forename: Tung-Lung
authors.initials: TL
authors.lastname: Tsai
authors.forename: Shyh-Kuan
authors.initials: SK
authors.lastname: Tai
authors.forename: Shyue-Yih
authors.initials: SY
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery*; D002610:Cheek; D055088:Early Detection of Cancer / Q000379:methods*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery*; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000175:diagnosis / Q000517:prevention & control; D007089:Image Enhancement / Q000379:methods; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000601:surgery*; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D009959:Oropharyngeal Neoplasms / Q000175:diagnosis / Q000517:prevention & control; D011230:Precancerous Conditions / Q000175:diagnosis*; D000077195:Squamous Cell Carcinoma of Head and Neck; D014062:Tongue Neoplasms / Q000601:surgery*