title: Split of HLA-DRw2 into subtypic specificities closely correlated to two HLA-D products.
abstract: Two B-lymphocyte-specific human alloantisera were studied, PA59 and 51.23. They identify two new HLA-DR alleles, which are both subtypic to HLA-DRw2. Moreover, they are closely correlated with two HLA-D products, Dw2 and tb24 (tb24 is a new specificity described by our group). Thus, DRw2 can be "split" into two subtypic specificities that have been named TO60 and TO61, which appear more strongly correlated with HLA-D antigens. Absorption studies demonstrated cytotoxicity-negative, absorption-positive (CYNAP) reactions, and cross-reactive groups of antibodies.
authors.affiliation: Centro CNR Immunogenetica ed Istocompatibilità, Institute of Medical Genetics, University of Turin, Via Santena 19, 10126, Turin, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Richiardi
authors.forename: M
authors.initials: M
authors.lastname: Belvedere
authors.forename: I
authors.initials: I
authors.lastname: Borelli
authors.forename: M
authors.initials: M
authors.lastname: De Marchi
authors.forename: E S
authors.initials: ES
authors.lastname: Curtoni