title: Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report.
abstract: In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
authors.affiliation: Department of Otorhinolaryngology, Catholic University of Sacred Heart, Rome, Italy.
authors.forename: Walter
authors.initials: W
authors.lastname: Di Nardo
authors.forename: Paola
authors.initials: P
authors.lastname: Cattani
authors.forename: Alessandro
authors.initials: A
authors.lastname: Scorpecci
authors.forename: Sara
authors.initials: S
authors.lastname: Giannantonio
authors.forename: Sara
authors.initials: S
authors.lastname: D'Onghia
authors.forename: Giovanni
authors.initials: G
authors.lastname: Fadda
authors.forename: Gaetano
authors.initials: G
authors.lastname: Paludetti
mesh_terms: D002872:Chromosome Deletion; D019929:Cochlear Implantation; D000072259:Connexin 26; D017630:Connexins / Q000235:genetics; D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000235:genetics* / Q000821:virology; D004279:DNA, Viral / Q000302:isolation & purification*; D003638:Deafness / Q000235:genetics* / Q000534:rehabilitation* / Q000821:virology; D004710:Endolymph / Q000821:virology*; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D017630:Connexins; D004279:DNA, Viral; D000072259:Connexin 26