title: Supramaximal verification of peak oxygen uptake in adolescents with cystic fibrosis.
abstract: OBJECTIVE
  To study whether peak oxygen uptake ((Equation is included in full-text article VO₂ peak), attained in traditional cardiopulmonary exercise testing (CPET) in adolescents with cystic fibrosis (CF), could be verified by a supramaximal exercise test.
  
  
  METHODS
  Sixteen adolescents with CF (forced expiratory volume in 1 second as % of predicted [range, 45%-117%]) volunteered and successively performed CPET and a supramaximal test (Steep Ramp Test [SRT] protocol).
  
  
  RESULTS
  Cardiopulmonary exercise testing and the SRT resulted in comparable cardiorespiratory peak values. We found no significant difference in oxygen uptake ((Equation is included in full-text article VO₂ peak/kg) between CPET and the SRT (38.9 ± 7.4 and 38.8 ± 8.5 mL min kg, respectively; P = .81). We found no systemic bias for CPET and SRT measurements of (Equation is included in full-text article VO₂  peak/kg and no differences between CPET and SRT (Equation is included in full-text article VO₂  peak values within and between the maximal and non-maximal effort groups (P > .4).
  
  
  CONCLUSIONS
  The (Equation is included in full-text article VO₂  peak measured in CPET seems to reflect the true (Equation is included in full-text article.)O2 peak in adolescents with CF.
authors.affiliation: Child Development & Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Maarten S
authors.initials: MS
authors.lastname: Werkman
authors.forename: Hendrik J
authors.initials: HJ
authors.lastname: Hulzebos
authors.forename: Pauline B
authors.initials: PB
authors.lastname: van de Weert-van Leeuwen
authors.forename: Hubertus G M
authors.initials: HG
authors.lastname: Arets
authors.forename: Paul J M
authors.initials: PJ
authors.lastname: Helders
authors.forename: Tim
authors.initials: T
authors.lastname: Takken
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000704:Analysis of Variance; D003550:Cystic Fibrosis / Q000534:rehabilitation*; D016552:Ergometry; D005080:Exercise Test; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D010101:Oxygen Consumption; D011446:Prospective Studies; D012720:Severity of Illness Index; D014797:Vital Capacity