title: Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11.
abstract: This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34% (95% CI: -10 - 60%) if vaccinated only with monovalent vaccine in the 2009/10 season; 46% (95% CI: 7 - 69%) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63% (95% CI: 37 - 78%) if vaccinated in both seasons.
authors.affiliation: Health Protection Agency Health Protection Services - Colindale, London, UK. richard.pebody@HPA.org.uk
authors.forename: R
authors.initials: R
authors.lastname: Pebody
authors.forename: P
authors.initials: P
authors.lastname: Hardelid
authors.forename: Dm
authors.initials: D
authors.lastname: Fleming
authors.forename: J
authors.initials: J
authors.lastname: McMenamin
authors.forename: N
authors.initials: N
authors.lastname: Andrews
authors.forename: C
authors.initials: C
authors.lastname: Robertson
authors.forename: Dr
authors.initials: D
authors.lastname: Thomas
authors.forename: P
authors.initials: P
authors.lastname: Sebastianpillai
authors.forename: J
authors.initials: J
authors.lastname: Ellis
authors.forename: W
authors.initials: W
authors.lastname: Carman
authors.forename: T
authors.initials: T
authors.lastname: Wreghitt
authors.forename: M
authors.initials: M
authors.lastname: Zambon
authors.forename: Jm
authors.initials: J
authors.lastname: Watson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D058873:Pandemics; D012621:Seasons; D018571:Sentinel Surveillance; D016896:Treatment Outcome; D006113:United Kingdom / Q000453:epidemiology; D014611:Vaccination / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines