title: Cerebral perfusion abnormalities in cases of Down syndrome.
abstract: A SPECT (single photon emission computed tomography using Tc-99m HMPAO) study of brain with segmental quantitative analysis was conducted to access the cerebral perfusion in cases of Downs syndrome (DS). Varying level of brain hypo-perfusion was documented, probably explaining the neurophysiologic basis of cognitive and neuropsychological deficits, which are not well understood in DS.
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Gupta
authors.forename: B Venkat
authors.initials: BV
authors.lastname: Ratnam
mesh_terms: D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D055420:Perfusion Imaging; D015899:Tomography, Emission-Computed, Single-Photon