title: Immunoglobulin isoantigens (allotypes) in the mouse : V. Characterization of IgM allotypes.
abstract: Murine antisera raised against allogeneic lymphoid cells often contain antibodies to IgM allotypes. Rarely, allotypic antibodies to IgM have been found after immunization withB. pertussis anti-B. pertussis conjugates. Using both types of antibodies, we have defined a new constant-region locus for both secreted and membrane-bound μ chains. This locus,Ig-6, is closely linked to the previously described H-chain constant-region loci (Ig-1 throughIg-5) and is subject to allelic exclusion. We have identified three alleles and four antigenic specificities ofIg-6.
authors.affiliation: Department of Genetics, Stanford University School of Medicine, 94305, Stanford, California.
authors.forename: S J
authors.initials: SJ
authors.lastname: Black
authors.forename: J W
authors.initials: JW
authors.lastname: Goding
authors.forename: G A
authors.initials: GA
authors.lastname: Gutman
authors.forename: L A
authors.initials: LA
authors.lastname: Herzenberg
authors.forename: M R
authors.initials: MR
authors.lastname: Loken
authors.forename: B A
authors.initials: BA
authors.lastname: Osborne
authors.forename: W
authors.initials: W
authors.lastname: van der Loo
authors.forename: N L
authors.initials: NL
authors.lastname: Warner