title: Usefulness of combined PET/CT for patient with epithelial ovarian cancer showing recurrence based on tumor marker CA125.
abstract: We report the case of a 41-year-old patient with epithelial ovarian cancer of stage IIIc. One year and nine months after completion of chemotherapy performed after surgery, the level of the tumor marker CA125 began to increase gradually. Conventional computed tomography (CT) and magnetic resonance imaging (MRI) were performed, but the recurrence site could not be determined clearly. However, combined positron emission tomography/computed tomography (PET/CT) revealed a metastasis in the right external iliac lymph node. This allowed commencement of chemotherapy at an early recurrent stage and subsequently the level of CA125 showed a significant decrease.
authors.affiliation: Department of Obstetrics and Gynecology, Tokai University School of Medicine, Isehara, Kanagawa, Japan. mura-to@is.icc.u-tokai.ac.jp
authors.forename: Toshinari
authors.initials: T
authors.lastname: Muramatsu
authors.forename: Eiko
authors.initials: E
authors.lastname: Yamashita
authors.forename: Kazumi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Taro
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Hitomi
authors.initials: H
authors.lastname: Tsukada
authors.forename: Akane
authors.initials: A
authors.lastname: Kondo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hirasawa
authors.forename: Masaru
authors.initials: M
authors.lastname: Murakami
authors.forename: Seiei
authors.initials: S
authors.lastname: Yasuda
authors.forename: Mikio
authors.initials: M
authors.lastname: Mikami
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism*; D018394:CA-125 Antigen / Q000378:metabolism*; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis; D009375:Neoplasms, Glandular and Epithelial / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D049268:Positron-Emission Tomography / Q000379:methods*; D012008:Recurrence; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen