title: A case of recurrence of congenital ocular toxoplasmosis with frosted branch angiitis (ocular toxoplasmosis with frosted branch angiitis).
abstract: OBJECTIVE
  To describe a case of recurrence of congenital ocular toxoplasmosis with frosted branch angiitis.
  
  
  METHODS
  A 24-year-old woman presented with hyperemia in her right eye. Medical history included epilepsy at age 14 and mild mental retardation. Iridocyclitis and vitreous opacity were observed in the right eye, and furthermore widespread retinal vessel sheathing due to frosted branch angiitis was seen. Acyclovir was initiated for acute retinal necrosis with frosted branch angiitis. One week later, serologic tests showed elevated toxoplasma antibody level and toxoplasma antibody IgG level, and a white retinal exudative lesion with unclear margins was noted. Therefore, acetylspiramycin and prednisolone were initiated for a recurrence of congenital ocular toxoplasmosis. After treatment, inflammation subsided, the exudative lesion shrank, and the frosted branch angiitis improved.
  
  
  CONCLUSIONS
  We encountered a case of ocular toxoplasmosis due to recurrence of congenital toxoplasmosis with frosted branch angiitis. The clinical symptoms of ocular toxoplasmosis can be varied and the diagnosis should be kept in mind.
authors.affiliation: Department of Ophthalmology, Tokai University School of Medicine, Isehara, Kanagawa, Japan. youta@is.icc.u-tokai.ac.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Suzuki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Onouchi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nakagawa
authors.forename: Hideki
authors.initials: H
authors.lastname: Oohashi
authors.forename: Han
authors.initials: H
authors.lastname: Kaiken
authors.forename: Kenji
authors.initials: K
authors.lastname: Kawai
mesh_terms: D000906:Antibodies / Q000097:blood; D005260:Female; D006801:Humans; D012008:Recurrence; D014122:Toxoplasma / Q000276:immunology; D014125:Toxoplasmosis, Congenital / Q000150:complications* / Q000473:pathology* / Q000517:prevention & control*; D014126:Toxoplasmosis, Ocular / Q000209:etiology* / Q000473:pathology*; D014657:Vasculitis / Q000151:congenital* / Q000473:pathology*; D055815:Young Adult
chemical_list: D000906:Antibodies