title: Comparison of radiation dose and image quality of triple-rule-out computed tomography angiography between conventional helical scanning and a strategy incorporating sequential scanning.
abstract: Triple-rule-out computed tomographic angiography (TRO CTA), performed to evaluate the coronary arteries, pulmonary arteries, and thoracic aorta, has been associated with high radiation exposure. The use of sequential scanning for coronary computed tomographic angiography reduces the radiation dose. The application of sequential scanning to TRO CTA is much less well defined. We analyzed the radiation dose and image quality from TRO CTA performed at a single outpatient center, comparing the scans from a period during which helical scanning with electrocardiographically controlled tube current modulation was used for all patients (n = 35) and after adoption of a strategy incorporating sequential scanning whenever appropriate (n = 35). Sequential scanning was able to be used for 86% of the cases. The sequential-if-appropriate strategy, compared to the helical-only strategy, was associated with a 61.6% dose decrease (mean dose-length product of 439 mGy × cm vs 1,144 mGy × cm and mean effective dose of 7.5 mSv vs 19.4 mSv, respectively, p <0.0001). Similarly, a 71.5% dose reduction occurred among the 30 patients scanned with the sequential protocol compared to the 40 patients scanned with the helical protocol using either strategy (326 mGy × cm vs 1,141 mGy × cm and 5.5 mSv vs 19.4 mSv, respectively, p <0.0001). Although the image quality did not differ between the strategies, a nonstatistically significant trend was seen toward better quality in the sequential protocol than in the helical protocol. In conclusion, approaching TRO CTA with a diagnostic strategy of sequential scanning, as appropriate, can offer a marked reduction in the radiation dose while maintaining the image quality.
authors.affiliation: Department of Medicine, Cardiology Division, Columbia University Medical Center, New York, New York, USA.
authors.forename: Eric D
authors.initials: ED
authors.lastname: Manheimer
authors.forename: M Robert
authors.initials: MR
authors.lastname: Peters
authors.forename: Steven D
authors.initials: SD
authors.lastname: Wolff
authors.forename: Mehreen A
authors.initials: MA
authors.lastname: Qureshi
authors.forename: Prashanth
authors.initials: P
authors.lastname: Atluri
authors.forename: Gregory D N
authors.initials: GD
authors.lastname: Pearson
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Einstein
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000792:Angiography / Q000379:methods*; D001027:Aortography / Q000379:methods; D016477:Artifacts; D001822:Body Burden; D055424:Cardiac-Gated Imaging Techniques; D017023:Coronary Angiography / Q000379:methods; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods*; D036542:Tomography, Spiral Computed / Q000379:methods*
chemical_list: D000319:Adrenergic beta-Antagonists