title: A new anticoagulant for a new era: review of recent data on dabigatran etexilate.
abstract: Dabigatran etexilate is an oral direct thrombin inhibitor that could be administered in fixed doses and does not require laboratory monitoring. It is currently being evaluated through the RE-VOLUTION clinical trials program, which will involve more than 38,000 patients by the time it is completed. These clinical trials will evaluate the efficacy and safety of dabigatran etexilate for several indications. This article will review the clinical development of dabigatran, the published trial data, and the potential indications for this promising oral anticoagulant.
authors.affiliation: Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA. bishoy.faltas@rochestergeneral.org
authors.forename: Bishoy
authors.initials: B
authors.lastname: Faltas
mesh_terms: D000925:Anticoagulants / Q000494:pharmacology*; D001562:Benzimidazoles / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D000069604:Dabigatran; D006801:Humans; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D000925:Anticoagulants; D001562:Benzimidazoles; D015091:beta-Alanine; D000069604:Dabigatran