title: Efficient synthesis of 5H-cyclopenta[c]quinoline derivatives via palladium-catalyzed domino reactions of o-alkynylhalobenzene with amine.
abstract: A novel and efficient route for the synthesis of 5H-cyclopenta[c]quinoline derivatives via a palladium-catalyzed domino reaction of o-alkynylhalobenzene with amine is described. The starting materials are easily available, and the reaction proceeds smoothly with high efficiency, which shows broad scope with good functional group tolerance.
authors.affiliation: Department of Chemistry, Fudan University, Shanghai, People's Republic of China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Luo
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Pan
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D000588:Amines; D001555:Benzene Derivatives; D006846:Hydrocarbons, Halogenated; D011804:Quinolines; D010165:Palladium