title: Macular thinning associated with unilateral optic nerve hypoplasia.
abstract: The authors present the case of an 8-year-old boy with a long-term diagnosis of unilateral optic nerve hypoplasia (ONH) of unknown cause in the right eye. Spectral-domain optical coherence tomography (SD-OCT) of the central macula was consistent with hypoplasia greatest in the inner retinal layers, but also involving the outer retinal layers when compared with the unaffected contralateral eye. Although ONH is commonly associated with hypoplasia of the nerve fiber and ganglion cell layers, it can also be associated with hypoplasia of other layers in the inner and outer retina, including the outer nuclear and photoreceptor inner/outer segment layers, as evidenced by SD-OCT.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
authors.forename: Quan V
authors.initials: QV
authors.lastname: Hoang
authors.forename: Felix Y
authors.initials: FY
authors.lastname: Chau
authors.forename: Mahnaz
authors.initials: M
authors.lastname: Shahidi
authors.forename: Marilyn T
authors.initials: MT
authors.lastname: Miller
authors.forename: Michael P
authors.initials: MP
authors.lastname: Blair
mesh_terms: D002648:Child; D005124:Eye Abnormalities / Q000175:diagnosis / Q000209:etiology*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D009900:Optic Nerve / Q000002:abnormalities*; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence