title: Reactive tonsillar enlargement with strong 18F-FDG uptake after chemotherapy for tonsillar diffuse large B-cell lymphoma.
abstract: We describe a 14-year-old boy who exhibited left palatine tonsillar enlargement after 6 cycles of aggressive chemotherapy for diffuse large B-cell lymphoma of the right palatine tonsil. The cervical computed tomography scan at 4 months after completion of chemotherapy revealed enlargement of the left palatine tonsil in addition to the thymus without any clinical symptoms. The F-fluorodeoxyglucose positron emission tomography indicated focal areas of strong F-fluorodeoxyglucose uptake in the left palatine tonsil. Histologic examination confirmed tonsillar hyperplasia with no evidence of recurrence. Reactive tonsillar hyperplasia after chemotherapy is rarely reported.
authors.affiliation: Department of Pediatrics, Niigata University Graduate School of Medical and Dental Science, Asahimachi-dori Chuou-ku, Niigata, Japan. hosokai@med.niigata-u.ac.jp
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Hosokai
authors.forename: Chihaya
authors.initials: C
authors.lastname: Imai
authors.forename: Takayuki
authors.initials: T
authors.lastname: Takachi
authors.forename: Sakiko
authors.initials: S
authors.lastname: Yoshida
authors.forename: Haruko
authors.initials: H
authors.lastname: Iwabuchi
authors.forename: Masaru
authors.initials: M
authors.lastname: Imamura
authors.forename: Makoto
authors.initials: M
authors.lastname: Uchiyama
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D005047:Etoposide / Q000008:administration & dosage; D019788:Fluorodeoxyglucose F18; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009367:Neoplasm Staging; D014066:Palatine Tonsil / Q000000981:diagnostic imaging* / Q000187:drug effects / Q000473:pathology*; D049268:Positron-Emission Tomography; D011239:Prednisolone / Q000008:administration & dosage; D019275:Radiopharmaceuticals; D014067:Tonsillar Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D019275:Radiopharmaceuticals; D003561:Cytarabine; D019788:Fluorodeoxyglucose F18; D014750:Vincristine; D005047:Etoposide; D003907:Dexamethasone; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; C027260:pirarubicin; D008727:Methotrexate