title: Characteristics of post donation information donors and comparison with appropriately deferred donors.
abstract: BACKGROUND
  Post donation information (PDI) is the most frequently reported biological product deviation (BPD) related to donor suitability and the health history screening process. PDI occurs when a deferrable health history known by the donor is not disclosed, but is subsequently disclosed at a future donation.
  
  
  METHODS
  PDI and appropriately deferred (AD) donors were identified at six US blood centers from July 1, 2006, to June 30, 2007. PDI and AD donors were categorized according to travel, medical, blood disease or exposure, and high-risk-sexual and high-risk-nonsexual deferrals. Information was obtained from BPD reports and blood center records. Predictors of PDI were identified using an adjusted logistic regression model controlling for select characteristics.
  
  
  RESULTS
  There were 2059 PDI and 36,512 AD donors. PDI donors were significantly more likely to be male, older, and more educated than AD donors. Medical and high-risk-sexual PDI donors were more likely to have more than six intervening donations before disclosure of deferrable history. PDI donors with a deferral reason due to high-risk behaviors (both sexual and nonsexual) were 2.3 and 2.6 times more likely to be PDI than the reference group (travel PDI donors).
  
  
  CONCLUSIONS
  No previous studies have described the characteristics of PDI donors or examined how PDI donors are different from AD donors for the same deferral reasons. We found that PDIs are more likely in older, male donors with higher levels of education when compared to AD donors.
authors.affiliation: Hoxworth Blood Center, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267-0055, USA. susan.wilkinson@uc.edu
authors.forename: Susan L
authors.initials: SL
authors.lastname: Wilkinson
authors.forename: Whitney R
authors.initials: WR
authors.lastname: Steele
authors.forename: Patrick M
authors.initials: PM
authors.lastname: High
authors.forename: David J
authors.initials: DJ
authors.lastname: Wright
mesh_terms: D000367:Age Factors; D001771:Blood Banks; D001782:Blood Donors / Q000193:education / Q000523:psychology*; D030881:Disclosure / Q000706:statistics & numerical data*; D004522:Educational Status; D005260:Female; D006402:Hematologic Diseases; D006801:Humans; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D014195:Travel; D014481:United States; D047568:Unsafe Sex