title: Ventricular tachycardia due to flumazenil administration.
abstract: Flumazenil is one of imidazo-benzodiazepine (Anexate) which has been generally used as benzodiazepine competitive antagonist for the treatment of benzodiazepine intoxication during recent decades. Some has recommended diagnostic usage in ICU as well, for suspected benzodiazepine intoxicated cases. In this study we present a patient intoxicated with lorazepam who developed a ventricular tachycardia after receiving flumazenil as therapeutic mean, though the attack was appropriately terminated by administration of a bolus dose of Amiodarone. We believe that the ventricular tachycardia onset in above mentioned case is secondary to Flumazenil administration in susceptible patient with previous history of ischemic heart disease. Ventricular tachycardia has rarely reported as flumazenil side effects.
authors.affiliation: Department of Emergency Medicine, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz-51664, IR Iran.
authors.forename: Hassan
authors.initials: H
authors.lastname: Soleimanpour
authors.forename: Behrad
authors.initials: B
authors.lastname: Ziapour
authors.forename: Sohrab
authors.initials: S
authors.lastname: Negargar
authors.forename: Ali
authors.initials: A
authors.lastname: Taghizadieh
authors.forename: Kamran
authors.initials: K
authors.lastname: Shadvar
mesh_terms: D005442:Flumazenil / Q000008:administration & dosage / Q000009:adverse effects*; D018757:GABA Modulators / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017180:Tachycardia, Ventricular / Q000139:chemically induced*
chemical_list: D018757:GABA Modulators; D005442:Flumazenil