title: Localisation of Mediterranean Kaposi's sarcoma in Morgagni's ventricle.
abstract: OBJECTIVE
  Head and neck involvement in Kaposi's Sarcoma (KS) is not unusual. However, laryngeal involvement is a relatively infrequent manifestation and ENT specialists should consider it in differential diagnosis in laryngeal lesions of AIDS patients and/or subjects from the Mediterranean area.
  
  
  METHODS
  Case report and review of the literature in English.
  
  
  METHODS
  Male patient presenting with a three-month history of cough and acute dyspnoea. Laryngoscopy identified a laryngeal mass occluding the glottic plane. Tracheotomy was then performed and the laryngeal lesion was removed. Histopathology showed neoplastic spindle cells that were positive to immunostain with CD-31 and CD-34, and immunoreactivity for HHV-8 was present. A diagnosis of KS was then suspected and confirmed after dermatological inspection.
  
  
  CONCLUSIONS
  Purple vascular mass lesions should lead in ENT to a high index of suspicion to exclude systemic diseases. Laryngeal KS must be included in the differential diagnosis of pigmented laryngeal lesions to plan correct management.
authors.affiliation: Dipartimento Discipline Chirurgiche e Oncologiche, U.O. Otorinolaringoiatria, Università degli Studi di Palermo, Italia. francesco.dispenza@gmail.com
authors.forename: F
authors.initials: F
authors.lastname: Dispenza
authors.forename: A
authors.initials: A
authors.lastname: Ballacchino
authors.forename: A
authors.initials: A
authors.lastname: Di Bernardo
authors.forename: N
authors.initials: N
authors.lastname: Mathur
authors.forename: S
authors.initials: S
authors.lastname: Gallina
mesh_terms: D000368:Aged; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D012514:Sarcoma, Kaposi / Q000378:metabolism / Q000473:pathology*