title: A case of juvenile idiopathic arthritis exhibiting repair of systemic bone erosion in response to continuation of MTX therapy after achievement of clinical remission.
abstract: We report a patient with rheumatoid factor-positive polyarthritis-type juvenile idiopathic arthritis (JIA) in whom clinical remission was achieved within 10 months after the start of methotrexate (MTX) therapy, and systemic repair of bone erosion was noted 8 months after clinical remission. These results indicate that even in cases of active JIA with the development of bone erosion, continuation of MTX therapy after the achievement of clinical remission can improve the prognosis, including repair of bone destruction.
authors.affiliation: Department of Orthopedic Surgery, Kishiwada City Hospital, 1001, Gakuhara-tyo, Kishiwada, Osaka, 596-8501, Japan. teru08251965@yahoo.co.jp
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Nakatani
authors.forename: Toru
authors.initials: T
authors.lastname: Maekawa
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Ishii
mesh_terms: D000293:Adolescent; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001171:Arthritis, Juvenile / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D005260:Female; D005384:Finger Joint / Q000000981:diagnostic imaging / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D010012:Osteogenesis / Q000187:drug effects*; D011859:Radiography; D012038:Regeneration / Q000187:drug effects*; D012074:Remission Induction; D014033:Toe Joint / Q000000981:diagnostic imaging / Q000187:drug effects / Q000502:physiology
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate