title: Autoxidative annulation cascade of the α-cyano β-TMS-capped alkynyl cycloalkanone system.
abstract: The autoxidative annulation cascade promoted by an α-cyano β-TMS-capped alkynyl cycloalkanone system under catalysis with pyridine in one oxygen atmosphere has proven to be highly viable. On the basis of this newly developed protocol, a variety of highly functionalized bicyclic frameworks can be effectively constructed.
authors.affiliation: Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, Taiwan, R O C.
authors.forename: Ying-Chieh
authors.initials: YC
authors.lastname: Wong
authors.forename: Min-Tsang
authors.initials: MT
authors.lastname: Hsieh
authors.forename: Prashanth K
authors.initials: PK
authors.lastname: Amancha
authors.forename: Chih-Lung
authors.initials: CL
authors.lastname: Chin
authors.forename: Cheng-Feng
authors.initials: CF
authors.lastname: Liao
authors.forename: Chun-Wei
authors.initials: CW
authors.lastname: Kuo
authors.forename: Kak-Shan
authors.initials: KS
authors.lastname: Shia
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D013237:Stereoisomerism; D014297:Trimethylsilyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007659:Ketones; D009570:Nitriles; D011725:Pyridines; D014297:Trimethylsilyl Compounds; C023666:pyridine