title: Ureteral rejection in isolated allograft ureter.
abstract: Ureteral rejection has been studied in the dog utilizing the isolated transplanted ureter technique. While on adequate immunosuppressive therapy, the allograft ureter remains functionally and histologically normal. When the drugs are discontinued, progressive destructive changes occur within the ureteral wall. As the muscle wall is destroyed the rejection process becomes irreversible. This process helps explain some of the findings seen during clinical renal transplantation.
authors.affiliation: McGuire Veterans Administration Hospital, Virginia, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Texter
authors.forename: G
authors.initials: G
authors.lastname: Bokinsky
authors.forename: B
authors.initials: B
authors.lastname: Broecker
mesh_terms: D000818:Animals; D004285:Dogs; D006084:Graft Rejection / Q000517:prevention & control; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D014513:Ureter / Q000637:transplantation*
chemical_list: D007166:Immunosuppressive Agents