title: Aspergillus lung disease in patients with sarcoidosis: a case series and review of the literature.
abstract: Chronic cavitary pulmonary aspergillosis (CCPA) has been associated with advanced lung diseases. Pulmonary sarcoidosis, a granulomatous inflammatory disorder, is associated with CCPA. We identified CCPA in 2% of cases in a large cohort of sarcoidosis patients. We found a lack of response to medical treatment and poor outcome in this subgroup.
authors.affiliation: Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Wayne State University School of Medicine, 3990 John R, 3 Hudson, Detroit, MI 48201, USA.
authors.forename: Tahuanty A
authors.initials: TA
authors.lastname: Pena
authors.forename: Ayman O
authors.initials: AO
authors.lastname: Soubani
authors.forename: Lobelia
authors.initials: L
authors.lastname: Samavati
mesh_terms: D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D055732:Pulmonary Aspergillosis / Q000188:drug therapy / Q000453:epidemiology*; D011743:Pyrimidines / Q000627:therapeutic use; D012307:Risk Factors; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; D065819:Voriconazole