title: Effects of transcutaneous electrical stimulation (1 pulse/sec) through custom-made disposable surface electrodes covering Omura's ST36 area of both legs on normal cell telomeres, oncogen C-fosAb2, integrin alpha5beta1, chlamydia trachomatis, etc. in breast cancer & alzheimer patients.
abstract: Our previous study indicated that when extremely reduced normal cell (NC) telomeres in various cancer patients are increased over 500 ng BDORT units, abnormally high cancer cell telomeres and cancer-related markers such as Oncogen C-fosAb2 (Onco.)& Integrin alpha5beta1 (Integ.), & 8-OH-dG as well as bacterial & viral infections, mercury, asbestos, chromium, & beta-amyloid (1-42) markedly reduced due to improved circulation & excretion of these substances in urine. Since 1995, we have been using press-needle stimulation of Omura's ST36 with 200x press-release procedure 4x a day, with significant improvements in various cancer patients. In this study, Transcutaneous Electrical Stimulation (TES) at 60 pulses/min, which is close to patient's heart rate, was given between Omura's ST36 of both legs of the breast cancer & Alzheimer's patients. After about 10 minutes of TES, NC telomeres increased from 1 yg (= 10-24 g) to 500-525 ng; Integ. reduced from 85-75 ng to 0.5 ng & Chlamydia trachomatis (CT) reduced from 4500-3500 ng to 0.5 ng. An additional 10 minutes TES increased NC telomeres to 800-875 ng, while Integ. reduced to 0.5 yg & CT became less than 0.1 yg. After a total 30 minutes of TES, NC telomeres increased to 1000-1200ng BDORT units, with decreases in Integ. and Onco. to less than 0.1 yg. CT reduced to << 0.1 yg. About 24 hours later, NC telomeres were still 300 ng & both Integ. and Onco. were 2.5 ng. CT was approximately 20 ng. In Alzheimer patient, abnormally high beta-Amyloid (1-42) of 7-12 ng markedly reduced to within normal value of less than 1.5 ng by 20-30 min TES. Stimulation beyond 30 minutes gradually reduced NC telomeres. TES pulse rate of 4 pulses/sec for the same patient initially increased NC telomere up to 750-950 ng BDORT units within 20 minutes, but when stimulation continued more than 20 min, NC telomeres rapidly reduced to -150 ng in less than 10 min of TES with reduced beneficial effects.
authors.affiliation: Heart Disease Research Foundation, Dept. of Family & Community Medicine, New York Medical College, USA. icaet@yahoo.com
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Omura
authors.forename: Yemeng
authors.initials: Y
authors.lastname: Chen
authors.forename: Olivia
authors.initials: O
authors.lastname: Lermand
authors.forename: Marilyn
authors.initials: M
authors.lastname: Jones
authors.forename: Harsha
authors.initials: H
authors.lastname: Duvvi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shimotsuura
mesh_terms: D015669:Acupuncture Points; D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism / Q000628:therapy*; D001943:Breast Neoplasms / Q000235:genetics / Q000378:metabolism / Q000628:therapy*; D002690:Chlamydia Infections / Q000235:genetics / Q000378:metabolism / Q000382:microbiology / Q000628:therapy*; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification; D004566:Electrodes; D005260:Female; D006801:Humans; D039081:Integrin alpha5beta1 / Q000235:genetics / Q000378:metabolism*; D007866:Leg; D008297:Male; D016760:Proto-Oncogene Proteins c-fos / Q000235:genetics / Q000378:metabolism*; D016615:Telomere / Q000235:genetics / Q000378:metabolism*; D004561:Transcutaneous Electric Nerve Stimulation / Q000295:instrumentation
chemical_list: D039081:Integrin alpha5beta1; D016760:Proto-Oncogene Proteins c-fos