title: Experimental comparison of cone beam CT (CBCT) reconstruction and multi-view reconstruction (MVR) for microangiography (MA) detector system.
abstract: The new Multi-View Reconstruction (MVR) method for generating 3D vascular images was evaluated experimentally. The MVR method requires only a few digital subtraction angiographic (DSA) projections to reconstruct the 3D model of the vessel object compared to 180 or more projections for standard CBCT. Full micro-CBCT datasets of a contrast filled carotid vessel phantom were obtained using a Microangiography (MA) detector. From these datasets, a few projections were selected for use in the MVR technique. Similar projection views were also obtained using a standard x-ray image intensifier (II) system. A comparison of the 2D views of the MVRs (MA and II derived) with reference micro-CBCT data, demonstrated best agreement with the MA MVRs, especially at the curved part of the phantom. Additionally, the full 3D MVRs were compared with the full micro-CBCT 3D reconstruction resulting for the phantom with the smallest diameter (0.75 mm) vessel, in a mean centerline deviation from the micro-CBCT derived reconstructions of 29 μm for the MA MVR and 48 μm for the II MVR. The comparison implies that an MVR may be substituted for a full micro-CBCT scan for evaluating vessel segments with consequent substantial savings in patient exposure and contrast media injection yet without substantial loss in 3D image content. If a high resolution system with MA detector is used, the improved resolution could be well suited for endovascular image guided interventions where visualization of only a small field of view (FOV) is required.
authors.affiliation: Toshiba Stroke Research Center, State University of New York at Buffalo, Buffalo, NY 14214.
authors.forename: Vikas
authors.initials: V
authors.lastname: Patel
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Kuhls
authors.forename: Peter B
authors.initials: PB
authors.lastname: Noël
authors.forename: Alan
authors.initials: A
authors.lastname: Walczak
authors.forename: Ciprian N
authors.initials: CN
authors.lastname: Ionita
authors.forename: Ravishankar
authors.initials: R
authors.lastname: Chityala
authors.forename: Rekha
authors.initials: R
authors.lastname: Tranquebar
authors.forename: Hussain S
authors.initials: HS
authors.lastname: Rangwala
authors.forename: Snehal S
authors.initials: SS
authors.lastname: Kasodekar
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Hoffmann
authors.forename: Daniel
authors.initials: D
authors.lastname: Bednarek
authors.forename: Stephen
authors.initials: S
authors.lastname: Rudin