title: Benefits of pulmonary rehabilitation in idiopathic pulmonary fibrosis.
abstract: BACKGROUND
  Information on the benefits of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF) is growing, but PR's effects on certain important outcomes is lacking.
  
  
  METHODS
  We conducted a pilot study of PR in IPF and analyzed changes in functional capacity, fatigue, anxiety, depression, sleep, and health status from baseline to after completion of a standard, 6-week PR program.
  
  
  RESULTS
  Six-min walk distance improved a mean ± standard error 202 ± 135 feet (P = .01) from baseline. Fatigue Severity Scale score also improved significantly, declining an average 1.5 ± 0.5 points from baseline. There were trends toward improvement in anxiety, depression, and health status.
  
  
  CONCLUSIONS
  PR improves functional capacity and fatigue in patients with IPF. (Clinical Trials.gov registration NCT00692796.)
authors.affiliation: Autoimmune Lung Center and Interstitial Lung Disease Program, National Jewish Health, Denver, Colorado 80206, USA. swigrisj@njc.org
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Swigris
authors.forename: Diane L
authors.initials: DL
authors.lastname: Fairclough
authors.forename: Marianne
authors.initials: M
authors.lastname: Morrison
authors.forename: Barry
authors.initials: B
authors.lastname: Make
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Kozora
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Brown
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Wamboldt
mesh_terms: D000368:Aged; D001007:Anxiety / Q000503:physiopathology / Q000517:prevention & control; D003863:Depression / Q000503:physiopathology / Q000517:prevention & control; D005221:Fatigue / Q000503:physiopathology / Q000517:prevention & control; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D015233:Models, Statistical; D010865:Pilot Projects; D011658:Pulmonary Fibrosis / Q000534:rehabilitation*; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000503:physiopathology / Q000517:prevention & control; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D016138:Walking / Q000502:physiology