title: Pain in malignant hematology.
abstract: Pain is frequently experienced by patients with hematological malignancies, although it often receives little attention. Different underlying causes and mechanisms may sustain several pain syndromes in hematological malignant patients. Pain may be due to disease itself, to disease-related complications, to iatrogenic causes or may be associated with unrelated medical conditions. The management of pain in this setting requires a multidisciplinary approach, integrating analgesics and causal interventions. An accurate diagnostic assessment and the identification of the underlying causes and pathogenetic mechanisms may dictate the treatment approach. For most pain patients, the WHO's three-step analgesic scale for cancer pain relief can provide adequate relief with oral options, although difficult-to-treat pain syndromes, requiring a more complex treatment approach, may also be observed.
authors.affiliation: Hematology Unit, S. Eugenio Hospital, Rome, Italy. pniscola@gmail.com
authors.forename: Pasquale
authors.initials: P
authors.lastname: Niscola
authors.forename: Andrea
authors.initials: A
authors.lastname: Tendas
authors.forename: Laura
authors.initials: L
authors.lastname: Scaramucci
authors.forename: Marco
authors.initials: M
authors.lastname: Giovaninni
authors.forename: Luca
authors.initials: L
authors.lastname: Cupelli
authors.forename: Vitaliana
authors.initials: V
authors.lastname: De Sanctis
authors.forename: Gregorio Antonio
authors.initials: GA
authors.lastname: Brunetti
authors.forename: Francesco
authors.initials: F
authors.lastname: Bondanini
authors.forename: Roberto
authors.initials: R
authors.lastname: Palumbo
authors.forename: Michela
authors.initials: M
authors.lastname: Lamanda
authors.forename: Roberta
authors.initials: R
authors.lastname: Battistini
authors.forename: Claudio
authors.initials: C
authors.lastname: Cartoni
authors.forename: Claudio
authors.initials: C
authors.lastname: Romani
authors.forename: Edoardo
authors.initials: E
authors.lastname: Arcuri
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D019337:Hematologic Neoplasms / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D010146:Pain / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D010147:Pain Measurement
chemical_list: D000700:Analgesics