title: [The efficacy and toxicity of the FUDR-based regimen in the treatment of advanced non-small cell lung cancer].
abstract: BACKGROUND
  To evaluate the efficacy and toxicity of the FUDR-based regimen in the treatment of advanced non-small cell lung cancer.
  
  
  METHODS
  Fifty patients in group A received the L/FUDR-EP regimen, while 42 patients in group B were given the L/FEP regimen. The response and toxicity were evaluated after three courses of treatment.
  
  
  RESULTS
  The therapeutic response of group A and group B were 40.0% and 38.1% respectively (P > 0.05). The toxicities such as marrow inhibition, gastrointestinal symptoms, alopecia and local phlebitis were remarkably lower in group A than those of group B (P < 0.01).
  
  
  CONCLUSIONS
  The FUDR based regimen is effective to the advanced NSCLC, and its toxicity is lower than 5-FU.
authors.affiliation: Department of Medical Oncology, The Fourth Hospital, Hebei Medical University, Shijiazhuang, Hebei 050011, P.R.China.
authors.forename: Shuqin
authors.initials: S
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Wang
authors.forename: Baoe
authors.initials: B
authors.lastname: Zhai