title: Eosinophilic pleural effusion complicating allergic bronchopulmonary aspergillosis.
abstract: Allergic bronchopulmonary aspergillosis (ABPA) is primarily a disease of patients with cystic fibrosis or asthma, who typically present with bronchial obstruction, fever, malaise, and expectoration of mucus plugs. We report a case of a young man with a history of asthma who presented with cough, left-sided pleuritic chest pain and was found to have lobar atelectasis and an eosinophilic, empyematous pleural effusion. Bronchoscopy and sputum cultures grew Aspergillus fumigatus, and testing confirmed strong allergic response to this mold, all consistent with a diagnosis of ABPA. This novel and unique presentation of ABPA expands on the differential diagnosis of eosinophilic pleural effusions.
authors.affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USA.
authors.forename: Austin N
authors.initials: AN
authors.lastname: Kirschner
authors.forename: Erica
authors.initials: E
authors.lastname: Kuhlmann
authors.forename: Tomasz J
authors.initials: TJ
authors.lastname: Kuzniar
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D001249:Asthma / Q000150:complications* / Q000382:microbiology; D004804:Eosinophils; D006801:Humans; D008297:Male; D010996:Pleural Effusion / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D013902:Radiography, Thoracic; D013183:Sputum / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone