title: Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey.
abstract: An ethnobotanical survey was conducted on plants used traditionally for the management of tuberculosis in five local government areas of Ogun State, Nigeria, in a bid to document herbs used in the management of tuberculosis with the aim of identifying possible drug lead from the phytomedicine of these communities. A semi-structured questionnaire was used to obtain the required information on the use of herbal remedies for the management. A total of 50 respondents made up of herbalists (40.0%), herb sellers (52.0%) and traditional medicine practitioners (8.0%) were interviewed in the study. The dominant age of respondents was in the range of 21-40 years (72.0%). Duration of treatment of tuberculosis with herbs was between 2-12 weeks. A total of 36 plants belonging to 20 families were proffered for the management of tuberculosis. Eighty four percent (42%) of the 50 respondents interviewed said that their clients observed no side effects and that the herbs were either available in the forest or purchased from the markets. Cola acumminata (fruit), Garcinia kola (leaf), Vitallaria parodoxa (oil), Costus afer (stem), Pycnanthus angolensis (stem bark) and Aframomum melegueta (fruit) were the most frequently mentioned herbs. The ethnomedicines of the studied areas of Ogun State, Nigeria seem to have a high potential as a source of drug discovery of anti-tuberculosis. This is of utmost importance because people living with human immunodeficiency virus (HIV) are susceptible to tuberculosis.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu, Nigeria.
authors.forename: Omonike O
authors.initials: OO
authors.lastname: Ogbole
authors.forename: Edith O
authors.initials: EO
authors.lastname: Ajaiyeoba
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D019448:Ethnobotany; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D016488:Medicine, African Traditional; D008875:Middle Aged; D009549:Nigeria; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011795:Surveys and Questionnaires; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D010936:Plant Extracts