title: Cementless total hip arthroplasty for the treatment of advanced tuberculosis of the hip.
abstract: The question of whether a total hip arthroplasty (THA) should be attempted in a patient with a current or previous tuberculosis infection continues to cause controversy. The goal of this study was to evaluate the clinical result of cementless THA for the treatment of advanced tuberculosis of the hip. Eight patients with advanced tuberculosis of the hip treated by cementless THA were retrospectively analyzed. None of the patients had draining sinus preoperatively. For patients with a confirmed preoperative diagnosis of tuberculosis and elevated C-reactive protein and erythrocyte sedimentation rate, antituberculous medication was prescribed for at least 2 weeks preoperatively. Inflamed soft tissues and destroyed bones were completely curetted out intraoperatively. All 8 patients received 1-stage cementless THA after thorough debridement. Antituberculous medications were prescribed for all patients for the first 6 months postoperatively. No patient experienced wound-healing complications. Mean Harris Hip Score was 35 (range, 30-43) preoperatively and 91 (range, 87-95) at last follow-up. At an average 46-month follow-up (range, 34-59 months), no reactivation of tuberculosis was detected. All 8 patients revealed stability by bone ingrowth on both the socket and femoral stem. Cementless THA is a safe and effective procedure for advanced tuberculosis of the hip. With thorough debridement followed by a complete course of antituberculous chemotherapy, active tuberculous infection should not be considered a contraindication for THA.
authors.affiliation: Department of Orthopedic Surgery, Shanghai No. 6th People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of China.
authors.forename: Qiaojie
authors.initials: Q
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Shen
authors.forename: Yao
authors.initials: Y
authors.lastname: Jiang
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.forename: Yunsu
authors.initials: Y
authors.lastname: Chen
authors.forename: Junjie
authors.initials: J
authors.lastname: Shao
authors.forename: Xianlong
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D006621:Hip Joint / Q000601:surgery*; D006801:Humans; D007593:Joint Instability / Q000209:etiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014394:Tuberculosis, Osteoarticular / Q000150:complications* / Q000601:surgery*