title: Accuracy of thoracic aortic measurements assessed by contrast enhanced and unenhanced magnetic resonance imaging.
abstract: OBJECTIVE
  To assess, whether unenhanced balanced steady-state-free precession sequences provide axial thoracic aortic measurements comparable to contrast enhanced magnetic resonance angiography with good intra- and interobserver agreement.
  
  
  METHODS
  Enhanced and unenhanced sequences of the thoracic aorta in 23 consecutive patients were evaluated. Axial thoracic aortic diameters were measured at predefined levels by two independent readers. Pearson's correlation coefficient and Bland-Altman analysis were used to compare enhanced and unenhanced sequences. t-Test was used to determine possible significant differences between the measurements obtained by enhanced and unenhanced sequences. A p-value of less than .05 indicated statistical significance. Intraclass correlation coefficient and Bland-Altman were used for inter- and intraobserver correlation and agreement.
  
  
  RESULTS
  There was no significant difference in diameter measurements between enhanced and unenhanced sequences (ascending aorta, p=0.98; descending aorta, p=0.52). Bland-Altman revealed good agreement between enhanced and unenhanced sequences for ascending (mean bias, -0.01cm; with 95% limits of agreement, ±0.30cm) and descending aortic diameters (mean bias, 0.05cm; with 95% limits of agreement, ±0.30cm). Inter- and intraobserver agreement (mean bias, less than ±0.15; with 95% limits of agreement, less than ±0.42cm for all measurements) as well as correlation (r>0.8 for all measurements) were excellent.
  
  
  CONCLUSIONS
  Unenhanced balanced steady-state-free precession sequences enable rapid and accurate determination of axial thoracic aortic diameters with excellent inter- and intraobserver agreement, but without the risk of contrast media associated side-effects.
authors.affiliation: Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. groth.michael@googlemail.com
authors.forename: M
authors.initials: M
authors.lastname: Groth
authors.forename: F O
authors.initials: FO
authors.lastname: Henes
authors.forename: K
authors.initials: K
authors.lastname: Müllerleile
authors.forename: P
authors.initials: P
authors.lastname: Bannas
authors.forename: G
authors.initials: G
authors.lastname: Adam
authors.forename: M
authors.initials: M
authors.lastname: Regier
mesh_terms: D001013:Aorta, Thoracic / Q000473:pathology*; D001018:Aortic Diseases / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA