title: Laryngeal Kaposi sarcoma: case report and literature review.
abstract: OBJECTIVE
  Kaposi sarcoma is the most frequently-occurring neoplasm in AIDS patients. Laryngeal localization is infrequent. We discuss the management options for laryngeal Kaposi sarcoma based on a literature review.
  
  
  METHODS
  A 42 year old, HIV-positive male receiving HAART therapy presented with mild hoarseness and sore throat. Fiberoptic laryngeal examination identified a small purple lesion in the right ventricular fold. He underwent biopsy under general anaesthesia. The lesion was histologically diagnosed as a Kaposi sarcoma. Systemic treatment was pursued, but 6 weeks later the patient developed severe dysphagia and acute airway obstruction when the lesion became glotto-supraglottic and obstruced the airway. Transoral tumour vaporization with a CO2 laser was performed in the emergency department. Post-operative chemotherapy was administered. Three months later, the patient was completely asymptomatic and the laryngeal examination was normal.
  
  
  CONCLUSIONS
  Transoral CO2 laser vaporization combined with chemotherapy is a valid option for managing obstructive laryngeal Kaposi sarcoma.
authors.affiliation: ENT&Head Neck, Université Catholique de Louvain, Cliniques Universitaires de Mont-Godinne, Yvoir, Belgium. george.lawson@uclouvain.be
authors.forename: G
authors.initials: G
authors.lastname: Lawson
authors.forename: N
authors.initials: N
authors.lastname: Matar
authors.forename: S
authors.initials: S
authors.lastname: Kesch
authors.forename: N
authors.initials: N
authors.lastname: Levêque
authors.forename: M
authors.initials: M
authors.lastname: Remacle
authors.forename: M C
authors.initials: MC
authors.lastname: Nollevaux
authors.forename: Ch
authors.initials: Ch
authors.lastname: Doyen
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology / Q000601:surgery; D015658:HIV Infections / Q000150:complications; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D054020:Lasers, Gas; D008297:Male; D012514:Sarcoma, Kaposi / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery