title: Robotic prostatectomy in a patient with hemophilia.
abstract: Given the rich blood supply to the prostate and the adjacent Santorini's plexus, radical prostatectomy is associated with significant blood loss even in patients with normal coagulation profiles. In patients with hemophilia, any surgical procedure carries a risk of significant hemorrhage due to a deficiency of factors in the coagulation cascade. For these reasons, hemophiliac patients have often been encouraged to undergo radiation or other forms of nonsurgical treatment for clinically localized prostate cancer. However, the decreased blood loss associated with a laparoscopic/robotic approach and appropriate perioperative factor transfusions can minimize the risk of hemorrhage during robotic-assisted radical prostatectomy. We present the case report of a successful robotic-assisted laparoscopic prostatectomy in a patient with mild hemophilia A, with an estimated blood loss for the procedure of 20 mL. We will focus on the perioperative management of the patient's factor replacement.
authors.affiliation: Department of Urology, The Mount Sinai Medical Center, New York, New York, USA.
authors.forename: Hugh J
authors.initials: HJ
authors.lastname: Lavery
authors.forename: Prathibha
authors.initials: P
authors.lastname: Senaratne
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Gainsburg
authors.forename: David B
authors.initials: DB
authors.lastname: Samadi
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D012371:Robotics