title: Pd-NHC catalyzed conjugate addition versus the Mizoroki-Heck reaction.
abstract: Ace of base: A catalytic system is presented that, solely by choice of the base, selectively switches between conjugate addition and the Mizoroki-Heck reaction of aryl halides with Michael acceptors (see scheme; R, R' = alkyl, aryl). For conjugate addition reactions, this avoids the preparation and use of organometallics.
authors.affiliation: Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
authors.forename: Aditya L
authors.initials: AL
authors.lastname: Gottumukkala
authors.forename: Johannes G
authors.initials: JG
authors.lastname: de Vries
authors.forename: Adriaan J
authors.initials: AJ
authors.lastname: Minnaard
mesh_terms: D002074:Butanones / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D020058:Styrene / Q000737:chemistry
chemical_list: D002074:Butanones; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C030011:carbene; D020058:Styrene; D010165:Palladium; C025383:benzylideneacetone; D008697:Methane