title: The pathogenesis of Duane's syndrome A nuclear dysgenesis hypothesis.
abstract: The authors propose a model that provides an explanation for the ocular motility, anatomical and electromyographic features of Duane's syndrome. It is proposed that, in the human embryo, the abducens nucleus is derived from the same stem cells as the oculomotor nucleus. Duane's syndrome represents a failure of differentiation and displacement of the abducens nucleus from the oculomotor nucleus in the 21- to 26-day-old human embryo.
authors.affiliation: Auburn District Hospital, Sydney, Australia.
authors.forename: N
authors.initials: N
authors.lastname: Saad
authors.forename: B
authors.initials: B
authors.lastname: Freeman
authors.forename: J
authors.initials: J
authors.lastname: Lee