title: Screening for retinopathy of prematurity in a tertiary hospital in Istanbul: incidence and risk factors.
abstract: OBJECTIVE
  To study the incidence and risk factors of retinopathy of prematurity (ROP) in premature infants examined in a tertiary hospital in Istanbul.
  
  
  METHODS
  Data of infants screened for ROP from April 2007 to September 2009 were retrospectively reviewed. Possible risk factors and eye examinations were recorded and analyzed using the chi-square test and univariate and multivariate regressions.
  
  
  RESULTS
  ROP was detected in 177 (34.3%) of the 517 infants enrolled in the study; 64 had mild ROP (77.4%) and 38 had severe ROP (22.6%). The mean gestational age and birth weight of patients who were treated for ROP were 28.6 ± 2.3 and 1,143.5 ± 337.4, respectively. Two of these infants had a gestational age of 32 g or greater and three had a birth weight of 1,500 g or greater. The multivariate regression analyses showed gestational age, birth weight, sepsis, respiratory distress syndrome, and length of oxygen therapy as independent predictors of ROP.
  
  
  CONCLUSIONS
  The incidence of ROP observed in this study was higher than that in developed countries and relatively more mature infants were affected. Criteria including gestational age of less than 34 weeks or birth weight of less than 2,000 g would have identified all infants who were at risk.
authors.affiliation: Department of Ophthalmology, Göztepe Training and Research Hospital, Istanbul, Turkey. aardagil@gmail.com
authors.forename: Aylin Ardagil
authors.initials: AA
authors.lastname: Akçakaya
authors.forename: Sevil Ari
authors.initials: SA
authors.lastname: Yaylali
authors.forename: Hasan Hasbi
authors.initials: HH
authors.lastname: Erbil
authors.forename: Fariz
authors.initials: F
authors.lastname: Sadigov
authors.forename: Asiye
authors.initials: A
authors.lastname: Aybar
authors.forename: Nihat
authors.initials: N
authors.lastname: Aydin
authors.forename: Güzide
authors.initials: G
authors.lastname: Akçay
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Acar
authors.forename: Cem
authors.initials: C
authors.lastname: Mesçi
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Yetik
mesh_terms: D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D010102:Oxygen Inhalation Therapy; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers / Q000706:statistics & numerical data*; D014421:Turkey / Q000453:epidemiology