title: Noninvasive detection of coronary artery stenoses with contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0 T.
abstract: OBJECTIVE
  To prospectively evaluate the accuracy of contrast-enhanced whole-heart coronary magnetic resonance angiography (CMRA) at 3.0 T, with the use of sublingual nitroglycerin and abdominal banding, for assessing significant stenosis (≥50% lumen diameter reduction) in patients with suspected coronary disease, using conventional coronary artery angiography as the reference standard.
  
  
  METHODS
  We prospectively studied 71 consecutive patients with suspected coronary artery disease scheduled for conventional coronary angiography. Contrast-enhanced whole-heart CMRA was performed after sublingual nitroglycerin with an abdominal banding rolled tightly along the side of the ribs. The diagnostic performance of CMRA for the detection of significant lesions was compared with that of quantitative coronary angiography.
  
  
  RESULTS
  The acquisition of CMRA was completed in 67 of 71 patients, with an average imaging time of 9.6 ± 3.2 min. The average navigator efficiency was 48%. The sensitivity, specificity as well as positive and negative predictive values of whole-heart CMRA for the detection of significant lesions on a segment-by-segment analysis were 91.4, 85.8, 48.7 and 98.5%, respectively, and in a patient-based analysis 94.6, 86.7, 89.7 and 92.9%, respectively.
  
  
  CONCLUSIONS
  Contrast-enhanced whole-heart CMRA with 3.0 T optimized by using sublingual nitroglycerin and abdominal banding methods permits reliable detection of significant obstructive coronary artery disease in patients with suspected coronary disease.
authors.affiliation: Department of Radiology, Union Hospital, Fujian Medical University, Fuzhou, PR China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Chen
authors.forename: Qing
authors.initials: Q
authors.lastname: Duan
authors.forename: Xunjing
authors.initials: X
authors.lastname: Xue
authors.forename: Lianglong
authors.initials: L
authors.lastname: Chen
authors.forename: Wenbin
authors.initials: W
authors.lastname: Ye
authors.forename: Lixin
authors.initials: L
authors.lastname: Jin
authors.forename: Bin
authors.initials: B
authors.lastname: Sun
mesh_terms: D000368:Aged; D003287:Contrast Media; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media