title: A comparison of predictability of cardiovascular events between each metabolic component in patients with metabolic syndrome based on the revised National Cholesterol Education Program criteria.
abstract: OBJECTIVE
  The prevalence of metabolic syndrome (MetS) generally varies depending on its diagnostic definition, and many different definitions inevitably lead to substantial confusion and lack of comparability between studies. Despite extensive research, there is still no gold standard for the definition of MetS, which continues to be a matter of debate. In this study, we investigate whether and to what extent its individual components are related to the risk of cardiovascular disease (CVD) in Korean population.
  
  
  METHODS
  We used data from the 2005 Korea National Health and Nutrition Examination Survey, which is a nationally representative survey of the noninstitutionalized civilian population. The study sample consisted of 1,406 Korean adults (587 men, 819 women) who were diagnosed with MetS based on the revised National Cholesterol Education Program (NCEP) criteria. Central obesity is defined as a waist circumference cutoff point reported in Asia-Pacific criteria for obesity based on waist circumference by the World Health Organization. CVD was defined as presence of stroke, myocardial infarction, or angina pectoris on a medical history questionnaire.
  
  
  RESULTS
  The CVD prevalence among the subjects was 6.8% for men and 8.6% for women. Besides age, the components of MetS showing a significant difference in the number of CVD events were high fasting glucose (FG) in men and high blood pressure (BP) and high FG in women. After adjusting for gender and age, high FG was shown to yield a significant difference (odds ratio: unadjusted 2.08, adjusted 1.81), alone among all MetS components. However, after adjusting for only age, no significant difference was found.
  
  
  CONCLUSIONS
  Fasting glucose level is the highest predicting factor for CVD in Korean patients with MetS based on the revised NECP definition.
authors.affiliation: Department of Family Medicine, Gachon University of Medicine and Science, Incheon, Korea.
authors.forename: In-Cheol
authors.initials: IC
authors.lastname: Hwang
authors.forename: Kyoung-Kon
authors.initials: KK
authors.lastname: Kim
authors.forename: Sun-Ha
authors.initials: SH
authors.lastname: Jee
authors.forename: Hee-Cheol
authors.initials: HC
authors.lastname: Kang
mesh_terms: D000367:Age Factors; D001786:Blood Glucose / Q000032:analysis; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology*; D016009:Chi-Square Distribution; D005260:Female; D006293:Health Promotion; D006306:Health Surveys; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D001786:Blood Glucose