title: MicroRNAs in inflammation and response to injuries induced by environmental pollution.
abstract: MicroRNAs (miRNAs) are small noncoding RNAs that regulate basic biological processes by posttranscriptional suppression of their target genes. Altered miRNA expression may lead to widespread gene expression changes and has been implicated in pathophysiological processes such as cancer and inflammation. In this review, we summarize the present knowledge about the role of miRNAs in inflammation and in the response to environmental agents and pollutants, such as cigarette smoke, ethanol, carcinogenic chemicals such as benzo(a)pyrene (BaP) and dioxin, and UV radiation.
authors.affiliation: Department of Medicine, Karolinska Institute, Stockholm, Sweden.
authors.forename: Enikö
authors.initials: E
authors.lastname: Sonkoly
authors.forename: Andor
authors.initials: A
authors.lastname: Pivarcsi
mesh_terms: D004785:Environmental Pollutants / Q000633:toxicity*; D004787:Environmental Pollution / Q000009:adverse effects*; D005786:Gene Expression Regulation / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D007249:Inflammation / Q000139:chemically induced* / Q000378:metabolism*; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D004785:Environmental Pollutants; D035683:MicroRNAs; D014028:Tobacco Smoke Pollution