title: Familial Miller Fisher syndrome.
abstract: Miller Fisher syndrome is an acute inflammatory polyradiculoneuropathy that is generally considered a variant of Guillain-Barré syndrome and is characterized by the clinical triad of ataxia, areflexia, and ophthalmoplegia. Several reports of familial Guillain-Barré syndrome have been reported, indicating a possible underlying genetic and/or environmental predisposition to the development of Guillain-Barré syndrome. A familial association in Miller Fisher syndrome has not previously been described in the literature. We report 2 cases of Miller Fisher syndrome presenting simultaneously in siblings, with a review of recent relevant literature.
authors.affiliation: Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ, USA. epeeples@phoenixchildrens.com
authors.forename: Eric
authors.initials: E
authors.lastname: Peeples
mesh_terms: D002675:Child, Preschool; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D019846:Miller Fisher Syndrome / Q000175:diagnosis* / Q000235:genetics* / Q000503:physiopathology