title: Maintenance of early pregnancy without early hormone support after frozen-thawed embryo transfer in hormone replacement treatment cycles.
abstract: OBJECTIVE
  To report two successful pregnancies after frozen-thawed ET in discontinued hormone replacement treatment cycles.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Two infertile patients.
  
  
  METHODS
  Hormone replacement treatment for endometrial preparation and frozen-thawed ET.
  
  
  METHODS
  Ovarian ultrasonography, serial hormone measurements of serum E2 and P, successful pregnancy, and follow-up visit.
  
  
  RESULTS
  One patient discontinued both E2 and P support 2 weeks after ET. The other discontinued estrogen support on the day preceding ET. No spontaneous follicle development was observed by ultrasonography, and no increase in serum P concentration was observed. Both patients became pregnant and achieved deliveries.
  
  
  CONCLUSIONS
  These two cases show that maintenance of pregnancy is possible without early hormone support in hormone replacement treatment cycles.
authors.affiliation: Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Tong
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Zhu
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.forename: Qiong-Xiao
authors.initials: QX
authors.lastname: Huang
authors.forename: Ling-Ying
authors.initials: LY
authors.lastname: Jiang
authors.forename: Chao
authors.initials: C
authors.lastname: Li
authors.forename: Xiao-Na
authors.initials: XN
authors.lastname: Lin
authors.forename: Song-Ying
authors.initials: SY
authors.lastname: Zhang
mesh_terms: D000328:Adult; D004334:Drug Administration Schedule; D004624:Embryo Transfer / Q000379:methods*; D004622:Embryo, Mammalian; D005260:Female; D005300:Fertility Agents, Female / Q000008:administration & dosage*; D005615:Freezing; D005865:Gestational Age; D020249:Hormone Replacement Therapy / Q000379:methods; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D011247:Pregnancy; D011255:Pregnancy Maintenance / Q000187:drug effects / Q000502:physiology*; D016896:Treatment Outcome; D028761:Withholding Treatment; D055815:Young Adult
chemical_list: D005300:Fertility Agents, Female