title: Synthesis of graphene oxide-based biocomposites through diimide-activated amidation.
abstract: In this work, a novel and facile method for covalent attachment of biomaterials to graphene oxide sheets (GOS) was developed. Four conjugates were obtained via the diimide-activated amidation reaction under ambient conditions. Final products were characterized by FT-IR spectroscopy, atomic force microscopy and transmission electron microscopy. Electrochemical characterization of the composite showed that the covalently bonded biomaterial retained its bioactivity. This method may provide a way for further preparation of graphene-based biodevices.
authors.affiliation: Center of Special Materials and Technology, Fudan University, Shanghai, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Shen
authors.forename: Bo
authors.initials: B
authors.lastname: Yan
authors.forename: Min
authors.initials: M
authors.lastname: Shi
authors.forename: Hongwei
authors.initials: H
authors.lastname: Ma
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Mingxin
authors.initials: M
authors.lastname: Ye
mesh_terms: D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D055664:Electrochemical Techniques; D006108:Graphite / Q000138:chemical synthesis* / Q000737:chemistry; D018625:Microscopy, Atomic Force; D010087:Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000577:Amides; D001672:Biocompatible Materials; D010087:Oxides; D006108:Graphite