title: Repair of radiographic joint damage following treatment with etanercept in psoriatic arthritis is demonstrable by 3 radiographic methods.
abstract: OBJECTIVE
  Psoriatic arthritis (PsA) is characterized by varied radiographic features. We describe a patient with PsA with severe radiographic damage that improved significantly following treatment with etanercept. The improvement was documented by several methods of radiographic assessment.
  
  
  METHODS
  Etanercept was introduced in September 2005. Radiographs of the hands and feet were read using 3 methods: the modified Steinbrocker method, the van der Heijde (vdH) modification of the Sharp method, and the Ratingen scoring system.
  
  
  RESULTS
  In July 2009, radiographs of the hands and feet showed improvement in erosion score and joint space narrowing, while bony proliferation remained the same [43 by modified Steinbrocker, 26 by the vdH Sharp score (12 for erosions and 14 for joint space narrowing), and 56 by the Ratingen (18 for erosion and 38 for proliferation].
  
  
  CONCLUSIONS
  The 3 radiographic methods were useful in demonstrating improvement in joint scores. The modified Steinbrocker method, which is the simplest, was able to reveal improvement in our patient.
authors.affiliation: Centre for Prognosis Studies in the Rheumatic Diseases, 1E-410B, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario M5T 2S8.
authors.forename: Lihi
authors.initials: L
authors.lastname: Eder
authors.forename: Vinod
authors.initials: V
authors.lastname: Chandran
authors.forename: Dafna D
authors.initials: DD
authors.lastname: Gladman
mesh_terms: D015535:Arthritis, Psoriatic / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000503:physiopathology; D000068800:Etanercept; D005260:Female; D005500:Follow-Up Studies; D033023:Foot Joints / Q000000981:diagnostic imaging* / Q000502:physiology; D050823:Hand Joints / Q000000981:diagnostic imaging* / Q000502:physiology; D006801:Humans; D007074:Immunoglobulin G / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D011859:Radiography / Q000379:methods*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology
chemical_list: D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept