title: Heparin-induced thrombocytopenia and warfarin-induced skin necrosis: case report.
abstract: This paper describes a case of heparin-induced thrombocytopenia complicated by warfarin-induced skin necrosis in a 74-year old female patient hospitalized with diagnoses of a hip fracture, deep vein thrombosis and pulmonary thromboembolism. Warfarin-induced skin necrosis is a rare complication of anticoagulant therapy, with high morbidity and mortality that may be associated with heparin-induced thrombocytopenia.
authors.affiliation: Pontifical Catholic University of Parana, Brazil. flavia_kaiber@yahoo.com.br
authors.forename: Flávia Larissa
authors.initials: FL
authors.lastname: Kaiber
authors.forename: Tiago Osternack
authors.initials: TO
authors.lastname: Malucelli
authors.forename: Eloína do Rocio Valenga
authors.initials: Edo R
authors.lastname: Baroni
authors.forename: Marcelo Derbly
authors.initials: MD
authors.lastname: Schafranski
authors.forename: Hélcio Takeshi
authors.initials: HT
authors.lastname: Akamatsu
authors.forename: Carolina Cecília Finkler
authors.initials: CC
authors.lastname: Schmidt
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D009336:Necrosis / Q000139:chemically induced; D012867:Skin / Q000473:pathology*; D013921:Thrombocytopenia / Q000139:chemically induced*; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin