title: Nickel-catalyzed cycloaddition of anthranilic acid derivatives to alkynes.
abstract: A nickel-catalyzed cycloaddition has been developed where readily available anthranilic acid derivatives react with alkynes to afford substituted indoles. The reaction involves oxidative addition of Ni(0) to an ester moiety, which allows intermolecular addition to alkynes via decarbonylation and 1,3-acyl migration.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan.
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Maizuru
authors.forename: Tasuku
authors.initials: T
authors.lastname: Inami
authors.forename: Takuya
authors.initials: T
authors.lastname: Kurahashi
authors.forename: Seijiro
authors.initials: S
authors.lastname: Matsubara
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D062367:ortho-Aminobenzoates / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007211:Indoles; D062367:ortho-Aminobenzoates; C031385:anthranilic acid; D009532:Nickel