title: BioGrid Australia facilitates collaborative medical and bioinformatics research across hospitals and medical research institutes by linking data from diverse disease and data types.
abstract: BioGrid Australia is a federated data linkage and integration infrastructure that uses the Internet to enable patient specific information to be utilized for research in a privacy protected manner, from multiple databases of various data types (e.g. clinical, treatment, genomic, image, histopathology and outcome), from a range of diseases (oncological, neurological, endocrine and respiratory) and across more than 20 health services, universities and medical research institutes. BioGrid has demonstrated an ability to facilitate powerful research into the causation of human disease and the prediction of disease and treatment outcomes. BioGrid has successfully implemented technology and processes that allow researchers to efficiently extract data from multiple sources, without compromising data security and privacy. This article reviews BioGrid's first seven years and how it has overcome 9 of its top 10 challenges.
authors.affiliation: Melbourne Health, BioGrid, Royal Melb Hospital, 300 Grattan St, Parkville, Victoria, 3050, Australia. robert.merriel@mh.org.au
authors.forename: Robert B
authors.initials: RB
authors.lastname: Merriel
authors.forename: Peter
authors.initials: P
authors.lastname: Gibbs
authors.forename: Terence J
authors.initials: TJ
authors.lastname: O'Brien
authors.forename: Marienne
authors.initials: M
authors.lastname: Hibbert
mesh_terms: D000047:Academies and Institutes; D001315:Australia; D035843:Biomedical Research / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D016494:Computer Security; D003299:Cooperative Behavior; D003625:Data Collection / Q000379:methods / Q000592:standards* / Q000639:trends; D016208:Databases, Factual / Q000592:standards*; D006801:Humans; D018907:Privacy