title: Risk factors for suicide attempt in an Arab kindred.
abstract: OBJECTIVE
  This explorative study examines correlates of suicidal behavior in an extended Arab kindred selected because of a high rate of suicidal behavior.
  
  
  METHODS
  Family members (n=468) aged 15 through 55 were assessed using a comprehensive structured psychiatric interview, the Composite International Diagnostic Interview (CIDI), which covers a wide range of psychopathology, including a spectrum of suicidal thoughts and behaviors. In addition, self-reported depression, anxiety, hopelessness, impulsivity and hostility, early childhood adversity, and suicidal behavior in first- and second-degree relatives were assessed.
  
  
  RESULTS
  Significant associations were found between suicidal thoughts and behavior, and the presence of family history of suicide, all forms of psychopathology and suicidal behaviors. In addition, impulsivity and hostility were also significantly associated with suicidality.
  
  
  CONCLUSIONS
  The absence of similar assessments in comparison families, makes it difficult to assess why this family appears to be at higher risk for suicidal behavior.
  
  
  CONCLUSIONS
  Risk correlates of suicidal behavior in the Arab kindred are similar to those reported from other parts of the world. These findings suggest that effective means of suicide prevention used in European populations may be successfully adapted to prevent suicide in this ethnic group as well. Since all forms of suicidal behavior in this population as well as in other Arab populations are increasing rapidly (Karam et al., 2008), these results have important implications for suicide prevention as well as for the understanding of the genetics of suicide.
authors.affiliation: Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, United States. hamdans@upmc.edu
authors.forename: Sami
authors.initials: S
authors.lastname: Hamdan
authors.forename: Nadine
authors.initials: N
authors.lastname: Melhem
authors.forename: Israel
authors.initials: I
authors.lastname: Orbach
authors.forename: Ilana
authors.initials: I
authors.lastname: Farbstein
authors.forename: Mohammad
authors.initials: M
authors.lastname: El-Haib
authors.forename: Alan
authors.initials: A
authors.lastname: Apter
authors.forename: David
authors.initials: D
authors.lastname: Brent
mesh_terms: D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D001008:Anxiety Disorders / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D018912:Arabs / Q000235:genetics*; D001714:Bipolar Disorder / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D015897:Comorbidity; D003241:Consanguinity; D003430:Cross-Sectional Studies; D003865:Major Depressive Disorder / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000208:ethnology* / Q000235:genetics*; D006801:Humans; D007557:Israel; D008297:Male; D001523:Mental Disorders / Q000208:ethnology* / Q000235:genetics*; D008875:Middle Aged; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D019966:Substance-Related Disorders / Q000208:ethnology / Q000235:genetics / Q000523:psychology; D013406:Suicide, Attempted / Q000208:ethnology* / Q000523:psychology; D014481:United States; D055815:Young Adult