title: The obesity epidemic and disordered sleep during childhood and adolescence.
abstract: The obesity pandemic is claiming its presence even among youngest of children and is clearly on the rise. Although the extent and implications of this massive increase in the prevalence of overweight and obese children are unclear, they are anticipated to be deleterious to global health outcomes and life expectancy. The potential interrelationships between sleep and obesity have gained recent attention. In this chapter, we initially examine the critical evidence supporting or refuting such proposed associations. In addition, the potential reciprocal roles of obesity and obstructive sleep apnea in the facilitation of their pathophysiology are also reviewed, along with their amplificatory effects on their respective morbidities.
authors.affiliation: Section of Pediatric Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, University of Chicago, 5721 S. Maryland Avenue, MC 8000, Suite K-160, Chicago, IL 60637, USA. dgozal@uchicago.edu
authors.forename: David
authors.initials: D
authors.lastname: Gozal
authors.forename: Leila
authors.initials: L
authors.lastname: Kheirandish-Gozal
mesh_terms: D000293:Adolescent; D000403:Airway Resistance / Q000502:physiology; D002648:Child; D015897:Comorbidity; D006801:Humans; D020738:Leptin / Q000502:physiology; D009765:Obesity / Q000453:epidemiology* / Q000503:physiopathology; D015995:Prevalence; D020181:Sleep Apnea, Obstructive / Q000453:epidemiology; D012893:Sleep Wake Disorders / Q000453:epidemiology* / Q000503:physiopathology
chemical_list: D020738:Leptin