title: A prospective study of parainfluenza virus type 4 infections in children attending daycare.
abstract: Studies of parainfluenza virus type 4 (PIV-4) have been limited by difficulty in culturing. We prospectively studied a cohort of 225 young children attending daycare followed for 165 child-years, using polymerase chain reaction to detect 12 viruses, including PIV-4. PIV-4 was second only to PIV-3, occurring in 9 of 87 (10%) PIV+ illnesses. PIV-4 illnesses were not more severe and not associated with a specific clinical syndrome.
authors.affiliation: Department of Pediatrics, Madigan Army Medical Center, Tacoma, WA 98431, USA. mary.fairchok@us.army.mil
authors.forename: Mary P
authors.initials: MP
authors.lastname: Fairchok
authors.forename: Emily T
authors.initials: ET
authors.lastname: Martin
authors.forename: Jane
authors.initials: J
authors.lastname: Kuypers
authors.forename: Janet A
authors.initials: JA
authors.lastname: Englund
mesh_terms: D002656:Child Day Care Centers; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D029482:Parainfluenza Virus 4, Human / Q000302:isolation & purification*; D011446:Prospective Studies; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D012137:Respiratory System / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D019351:Rubulavirus Infections / Q000453:epidemiology* / Q000473:pathology / Q000821:virology
chemical_list: D012367:RNA, Viral