title: Biological functions of microRNAs.
abstract: The small regulatory non-coding RNA molecules, known as microRNAs (miRNAs), have been recognized as potential regulator of gene expression and modulate the gene function at the post-transcriptional level. It is now clear that miRNA biogenesis and function are related to the molecular mechanisms of various clinical diseases, which can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death viral infection and tumorgenesis. Here, we review recent work and provide insight into the diverse roles of miRNAs.
authors.affiliation: Jiang Su University of Science and Technology, Zhenjiang City, 212018, Jiangsu Province, PR China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Xing Jia
authors.initials: XJ
authors.lastname: Shen
authors.forename: Quan
authors.initials: Q
authors.lastname: Zou
authors.forename: Qiao Ling
authors.initials: QL
authors.lastname: Zhao
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000235:genetics; D002454:Cell Differentiation / Q000235:genetics; D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D014780:Viruses / Q000235:genetics / Q000378:metabolism
chemical_list: D035683:MicroRNAs