title: Complete genome sequence of Mycoplasma haemofelis, a hemotropic mycoplasma.
abstract: Here, we present the genome sequence of Mycoplasma haemofelis strain Langford 1, representing the first hemotropic mycoplasma (hemoplasma) species to be completely sequenced and annotated. Originally isolated from a cat with hemolytic anemia, this strain induces severe hemolytic anemia when inoculated into specific-pathogen-free-derived cats. The genome sequence has provided insights into the biology of this uncultivatable hemoplasma and has identified potential molecular mechanisms underlying its pathogenicity.
authors.affiliation: School of Veterinary Sciences, University of Bristol, Langford BS40 5DU, UK. emi.barker@bris.ac.uk
authors.forename: Emily N
authors.initials: EN
authors.lastname: Barker
authors.forename: Chris R
authors.initials: CR
authors.lastname: Helps
authors.forename: Iain R
authors.initials: IR
authors.lastname: Peters
authors.forename: Alistair C
authors.initials: AC
authors.lastname: Darby
authors.forename: Alan D
authors.initials: AD
authors.lastname: Radford
authors.forename: Séverine
authors.initials: S
authors.lastname: Tasker
mesh_terms: D000743:Anemia, Hemolytic / Q000382:microbiology / Q000662:veterinary; D000818:Animals; D002371:Cat Diseases / Q000382:microbiology; D002415:Cats; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000235:genetics* / Q000302:isolation & purification; D009175:Mycoplasma Infections / Q000382:microbiology / Q000662:veterinary; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial