title: Stilbenes and flavonoids from Artocarpus nitidus subsp. lingnanensis.
abstract: The first stilbene possessing a γ-aminobutyric acid lactam function, artocarpene (1), and a new flavanone, 2-hydroxynaringenin 4'-O-β-d-glucopyranoside (2), were isolated from the stems of Artocarpus nitidus subsp. lingnanensis along with four known compounds, 2-hydroxynaringenin (3), oxyresveratrol (4), 3,4',5-trihydroxy-3'-prenylstilbene (5) and norartocarpetin (6). Their structures were elucidated on the basis of spectroscopic data. Compounds 1 exhibited weak antioxidant activity and 2 displayed weak cytotoxicity against human lung cancer A549 cell line.
authors.affiliation: Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Xingke Road 723, Tianhe District, Guangzhou 510650, PR China.
authors.forename: Huihui
authors.initials: H
authors.lastname: Ti
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.forename: Lidong
authors.initials: L
authors.lastname: Lin
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Wei
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D031622:Artocarpus / Q000737:chemistry*; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D013267:Stilbenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C560480:2-hydroxynaringenin 4'-O-beta-D-glucopyranoside; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D044950:Flavanones; D005419:Flavonoids; D013267:Stilbenes; C560481:artocarpene