title: Subacute sclerosing panencephalitis: a case report.
abstract: Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of childhood and early adolescence caused by persistent defective measles virus. Clinical manifestations appear many years after the acute measles infection. The incidence of SSPE has substantially declined after the introduction of an effective vaccine. We report a case of a child with SSPE that began with atonia, dysarthria, and intellectual deterioration without the presence of any particular EEG anomalies. We have reported this girl who was affected by this severe affliction in the hope that, because of the rarity of SSPE, it would not go undiagnosed.
authors.affiliation: Department of Pediatrics, University of Catania, Catania. terrenere178@tin.it
authors.forename: A D
authors.initials: AD
authors.lastname: Praticò
authors.forename: M
authors.initials: M
authors.lastname: Saporito
authors.forename: O
authors.initials: O
authors.lastname: Iacono
authors.forename: D
authors.initials: D
authors.lastname: Castellano-Chiodo
authors.forename: P
authors.initials: P
authors.lastname: Pavone
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D018450:Disease Progression; D004359:Drug Therapy, Combination; D004401:Dysarthria; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007542:Inosine Pranobex / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D008457:Measles / Q000150:complications*; D008458:Measles Vaccine / Q000009:adverse effects; D011379:Prognosis; D012720:Severity of Illness Index; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy
chemical_list: D000998:Antiviral Agents; D008458:Measles Vaccine; D016899:Interferon-beta; D007542:Inosine Pranobex