title: [Relationship between the expression of E-cadherin and MVD and its significance in lung cancer].
abstract: BACKGROUND
  To study the relationship between the expression of E-cadherin and MVD in lung cancer and its significance.
  
  
  METHODS
  The expressions of E-cadherin and factor VIII were detected in 104 lung cancer tissues by immunohistochemical method, and MVD was calculated by image analysis system.
  
  
  RESULTS
  The expression of E-cadherin was significantly related to the differentiation of lung cancer (P < 0.05). A negative correlation was observed between E-cadherin expression and MVD in lung cancer tissues (P= 0.047).
  
  
  CONCLUSIONS
  Downexpression of E-cadherin and increase of MVD may play an important role in the invasion and metastasis of lung cancer, and may also be used as a useful marker for tumor prognosis.
authors.affiliation: Department of Pathology, Tianjin Medical University, Tianjin 300070, P.R.China.
authors.forename: Xinyun
authors.initials: X
authors.lastname: Wang
authors.forename: Juhong
authors.initials: J
authors.lastname: Yang
authors.forename: Ying
authors.initials: Y
authors.lastname: Ma
authors.forename: Bo
authors.initials: B
authors.lastname: Cheng
authors.forename: Hongwei
authors.initials: H
authors.lastname: Zheng
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zheng
authors.forename: Congzhong
authors.initials: C
authors.lastname: Zhu
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Li