title: Dermatophytosis caused by Tricophyton rubrum as an opportunistic infection in patients with Cushing disease.
abstract: Trichophyton rubrum is a common agent found in superficial mycoses, which present ample non-inflammatory lesions, with chronic evolution, especially in immunocompromised patients. The hypercortisolism in Cushing's syndrome increases the risk of infections as a result of the immunosuppressive effect of glucocorticoids. The reported cases here refer to two different types of dermatophytosis caused by Trichophyton rubrum in patients with Cushing's disease, resistant to antifungal treatment. The disease remitted after the levels of cortisol went back to normal.
authors.affiliation: Adriano Jorge General Hospital Foundation, Manaus, AM, Brazil.
authors.forename: Isy
authors.initials: I
authors.lastname: Peixoto
authors.forename: Gustavo
authors.initials: G
authors.lastname: Maquine
authors.forename: Valeska Albuquerque
authors.initials: VA
authors.lastname: Francesconi
authors.forename: Fabio
authors.initials: F
authors.lastname: Francesconi
mesh_terms: D000328:Adult; D003480:Cushing Syndrome / Q000097:blood / Q000382:microbiology*; D003881:Dermatomycoses / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D014249:Trichophyton / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D006854:Hydrocortisone