title: A nanoscale DNA-Au dendrimer as a signal amplifier for the universal design of functional DNA-based SERS biosensors.
abstract: The use of a nanoscale DNA-Au dendrimer as a signal amplifier was proposed for the universal design of functional DNA-based ultra-sensitive SERS biosensors. This novel design combines the high specificity of functional DNA with the high sensitivity of surface-enhanced Raman scattering (SERS) spectroscopy, resulting in sensitivity superior to that of previously reported sensors.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Yun-Hong
authors.initials: YH
authors.lastname: Sun
authors.forename: Rong-Mei
authors.initials: RM
authors.lastname: Kong
authors.forename: Dan-Qing
authors.initials: DQ
authors.lastname: Lu
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Zhang
authors.forename: Hong-Min
authors.initials: HM
authors.lastname: Meng
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
authors.forename: Guo-Li
authors.initials: GL
authors.lastname: Shen
authors.forename: Ru-Qin
authors.initials: RQ
authors.lastname: Yu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007854:Lead / Q000032:analysis*; D012680:Sensitivity and Specificity; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D050091:Dendrimers; D007854:Lead; D006046:Gold; D004247:DNA