title: Utility values in Japanese patients with exudative age-related macular degeneration.
abstract: OBJECTIVE
  To investigate the utility values associated with visual loss due to age-related macular degeneration (AMD) in Japanese patients.
  
  
  METHODS
  Utility values in 48 Japanese patients with bilateral exudative AMD were measured using the time trade-off and standard gamble methods.
  
  
  RESULTS
  The time trade-off method utility values correlated with the best-corrected visual acuity (BCVA) in the better-seeing eye. The estimated utility values according to the BCVA in the better-seeing eye were 0.534 (BCVA, 0.01-0.15), 0.574 (0.2-0.3), 0.613 (0.4-0.6), and 0.653 (0.7-1.0). The utility values obtained by the standard gamble method were not significantly correlated with BCVA in the better-seeing eye.
  
  
  CONCLUSIONS
  The present results concur with those of previous studies showing that AMD causes a substantial decrease in patient utility values. The utility values obtained in the current study provide important information for use in cost-utility analysis of interventions for Japanese AMD patients.
authors.affiliation: Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan. yanagi-tky@umin.ac.jp
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yanagi
authors.forename: Takashi
authors.initials: T
authors.lastname: Ueta
authors.forename: Ryo
authors.initials: R
authors.lastname: Obata
authors.forename: Aya
authors.initials: A
authors.lastname: Iriyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukuda
authors.forename: Hideki
authors.initials: H
authors.lastname: Hashimoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000208:ethnology; D003362:Cost-Benefit Analysis; D005122:Exudates and Transudates; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008268:Macular Degeneration / Q000208:ethnology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D019057:Quality-Adjusted Life Years; D018434:Sickness Impact Profile; D014786:Vision Disorders / Q000208:ethnology / Q000523:psychology*; D014792:Visual Acuity / Q000502:physiology