title: Bladder tumor associated with phenacetin abuse: a case report and a review of the literature.
abstract: We herein report the case of a bladder tumor in an 85-year-old man who had been engaged in phenacetin abuse. He had been taking phenacetin owing to migraine headaches since he was 45 year of age. His total intake of phenacetin was approximately 7.3 to 11.5 kg over a period of years. He visited the Department of Urology in our hospital due to gross hematuria and pain on urination. IVP and a pelvic CT scan revealed a tumor mass on the right lateral wall of the urinary bladder. TUR-BT was performed. A histopathological examination of the resected specimen was diagnosed as urotherial carcinoma, grade 2∼3, pT2N0M0. To our acknowledge, only 24 cases of urotherial tumors owing to phenacetin abuse have been previously reported in the Japanese literature, making this the 25 th such case to be reported in Japan.
authors.affiliation: Department of Urology, Nerima General Hospital. hiro@jcom.home.ne.jp
authors.forename: Yosihiro
authors.initials: Y
authors.lastname: Nagata
authors.forename: Aiichiro
authors.initials: A
authors.lastname: Masuda
mesh_terms: D000369:Aged, 80 and over; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D005467:Floxuridine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010615:Phenacetin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D011859:Radiography; D019966:Substance-Related Disorders / Q000150:complications*; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology
chemical_list: D018712:Analgesics, Non-Narcotic; D005467:Floxuridine; D004317:Doxorubicin; C027260:pirarubicin; D010615:Phenacetin; C025034:doxifluridine