title: Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.
abstract: The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or pregnancy morbidity in combination with the persistent presence of circulating antiphospholipid antibodies: lupus anticoagulant, anticardiolipin antibodies and/or anti-β2-glycoprotein I antibodies in medium to high titers. The management of thrombosis in patients with APS is a subject of controversy. This set of recommendations is the result of an effort to produce guidelines for therapy within a group of specialist physicians in Cardiology, Neurology, Hematology, Rheumatology and Internal Medicine, with a clinical and research focus on APS.
authors.affiliation: Autoimmune Disease Research Unit, Department of Internal Medicine, Hospital de Cruces, University of the Basque Country, Barakaldo, Spain. r.irastorza@euskaltel.net
authors.forename: G
authors.initials: G
authors.lastname: Ruiz-Irastorza
authors.forename: M J
authors.initials: MJ
authors.lastname: Cuadrado
authors.forename: I
authors.initials: I
authors.lastname: Ruiz-Arruza
authors.forename: R
authors.initials: R
authors.lastname: Brey
authors.forename: M
authors.initials: M
authors.lastname: Crowther
authors.forename: R
authors.initials: R
authors.lastname: Derksen
authors.forename: D
authors.initials: D
authors.lastname: Erkan
authors.forename: S
authors.initials: S
authors.lastname: Krilis
authors.forename: S
authors.initials: S
authors.lastname: Machin
authors.forename: V
authors.initials: V
authors.lastname: Pengo
authors.forename: S
authors.initials: S
authors.lastname: Pierangeli
authors.forename: M
authors.initials: M
authors.lastname: Tektonidou
authors.forename: M
authors.initials: M
authors.lastname: Khamashta
mesh_terms: D026683:Advisory Committees; D017152:Antibodies, Antiphospholipid / Q000009:adverse effects / Q000097:blood*; D016736:Antiphospholipid Syndrome / Q000097:blood* / Q000150:complications / Q000276:immunology*; D002986:Clinical Trials as Topic; D003226:Congresses as Topic; D005260:Female; D006801:Humans; D011247:Pregnancy; D013781:Texas; D013927:Thrombosis / Q000097:blood / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*
chemical_list: D017152:Antibodies, Antiphospholipid