title: Enantioselective haloetherification by asymmetric opening of meso-halonium ions.
abstract: A new approach to enantioselective haloetherification reactions via desymmetrization of in situ-generated meso-halonium ions is described. The combination of N-haloamides as a halogen source and sodium salts of chiral phosphoric acids as catalysts can be used for the cyclization of symmetrical ene-diol substrates, yielding the haloetherification products under practical conditions in enantioenriched form.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Münster, Germany. ulrich.hennecke@uni-muenster.de
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hennecke
authors.forename: Christian H
authors.initials: CH
authors.lastname: Müller
authors.forename: Roland
authors.initials: R
authors.lastname: Fröhlich