title: Signet cell adenocarcinoma of the rectum metastatic to the orbit.
abstract: A 24-year-old man developed abdominal carcinomatosis from signet cell carcinoma of the rectum. His only distal metastasis involved the superior orbit. Orbital pathology showed signet cells with a characteristic immunopathologic pattern. No hereditary syndrome was found. The authors identified only 5 cases in the literature describing colorectal adenocarcinoma metastatic to the orbit, with 2 showing histopathology. The authors believe that this rare case represents the first illustrating bona fide signet cell colorectal cancer involving the orbit.
authors.affiliation: Department of Ophthalmology and Pathology, New York University Medical Center, New York, NY 10016, USA. norman.charles@nyumc.org
authors.forename: Norman C
authors.initials: NC
authors.lastname: Charles
authors.forename: Diana D
authors.initials: DD
authors.lastname: Ng
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Zoumalan
mesh_terms: D001763:Blepharoptosis / Q000209:etiology; D018279:Carcinoma, Signet Ring Cell / Q000556:secondary*; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000556:secondary*; D012004:Rectal Neoplasms / Q000473:pathology*; D055815:Young Adult