title: Circadian clock gene Per3 variants influence the postpartum onset of bipolar disorder.
abstract: Postpartum depression can mark the onset of bipolar disorder. The coding region of Per3 gene contains a variable-number tandem-repeat polymorphism, which has been shown to influence bipolar disorder onset and to affect breast cancer risk. We showed a relationship between Per3 polymorphism and postpartum depressive onset in bipolar disorder.
authors.affiliation: Department of Clinical Neurosciences, Scientific Institute and University Vita-Salute San Raffaele, Via Stamira d’Ancona 20, Milan, Italy. dallaspezia.sara@hsr.it
authors.forename: S
authors.initials: S
authors.lastname: Dallaspezia
authors.forename: C
authors.initials: C
authors.lastname: Lorenzi
authors.forename: A
authors.initials: A
authors.lastname: Pirovano
authors.forename: C
authors.initials: C
authors.lastname: Colombo
authors.forename: E
authors.initials: E
authors.lastname: Smeraldi
authors.forename: F
authors.initials: F
authors.lastname: Benedetti
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000235:genetics*; D019052:Depression, Postpartum / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D056950:Period Circadian Proteins / Q000235:genetics*; D011110:Polymorphism, Genetic; D049590:Postpartum Period / Q000235:genetics*; D020080:Tandem Repeat Sequences
chemical_list: C512644:PER3 protein, human; D056950:Period Circadian Proteins