title: Hepatitis C virus treatment with pegylated interferon-alfa therapy leading to generalized interstitial granuloma annulare and review of the literature.
abstract: We discuss the diagnosis and management of a case of generalized granuloma annulare (GA) occurring in a 49-year-old man when being treated with pegylated interferon-alfa for hepatitis C infection. In our case, the GA lesions remained despite an undetectable hepatitis C viral load. The GA resolved only with treatment cessation.
authors.affiliation: Divisions of 1Gastroenterology and 2Pathology, University of Toledo Medical Center, Toledo, OH.
authors.forename: Usman
authors.initials: U
authors.lastname: Ahmad
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Thomas
authors.initials: T
authors.lastname: Sodeman
authors.forename: Isam
authors.initials: I
authors.lastname: Daboul
mesh_terms: D000998:Antiviral Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004337:Drug Carriers; D004359:Drug Therapy, Combination; D016460:Granuloma Annulare / Q000139:chemically induced*; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols; D012254:Ribavirin / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D004337:Drug Carriers; D016898:Interferon-alpha; D011092:Polyethylene Glycols; D012254:Ribavirin