title: [Propranolol for treatment of subglottic hemangioma].
abstract: Subglottic hemangiomas are extremely dangerous due to its location and rapid growth during the proliferative phase. Many different treatments are described but these methods are still not satisfactory. Recently propranolol has been used as a new option in hemangioma therapy. We describe a case of 6-week infant with subglottic hemangioma discovered direct laryngoscopy, presented with dyspnoea and inspiratory stridor. After oral propranolol administration all baseline airway symptoms had resolved and endoscopic examination demonstrated significant regression of the hemangioma. We suggest that the propranolol should be used as a first-line treatment in subglottic hemangiomas in children.
authors.affiliation: Klinika Otolaryngologii Dzieciecej Uniwersytetu Medycznego w Białymstoku. kurzyna@tlen.pl
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kurzyna
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Hassmann-Poznańska
authors.forename: Jerzy
authors.initials: J
authors.lastname: Wójtowicz
authors.forename: Artur
authors.initials: A
authors.lastname: Bossowski
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005931:Glottis; D006391:Hemangioma / Q000151:congenital / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007822:Laryngeal Neoplasms / Q000151:congenital / Q000188:drug therapy*; D007828:Laryngoscopy / Q000379:methods; D011433:Propranolol / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol