title: A comparison of the effectiveness between amniotic membrane homogenate and transplanted amniotic membrane in healing corneal damage in a rabbit model.
abstract: OBJECTIVE
  To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model.
  
  
  METHODS
  The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group.
  
  
  RESULTS
  There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group.
  
  
  CONCLUSIONS
  Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.
authors.affiliation: Department of Life Science and Engineering, Harbin Institute of Technology, Harbin, China. guoqing-925@163.com
authors.forename: Qing
authors.initials: Q
authors.lastname: Guo
authors.forename: Jie
authors.initials: J
authors.lastname: Hao
authors.forename: Qian
authors.initials: Q
authors.lastname: Yang
authors.forename: Linan
authors.initials: L
authors.lastname: Guan
authors.forename: Shan
authors.initials: S
authors.lastname: Ouyang
authors.forename: Jianwen
authors.initials: J
authors.lastname: Wang
mesh_terms: D000650:Amnion; D000818:Animals; D001684:Biological Dressings; D003315:Cornea / Q000503:physiopathology; D065306:Corneal Injuries; D004195:Disease Models, Animal; D015807:Eye Injuries, Penetrating / Q000503:physiopathology / Q000601:surgery*; D011817:Rabbits; D014020:Tissue Extracts / Q000008:administration & dosage*; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*
chemical_list: D014020:Tissue Extracts