title: The pathophysiology of septic shock.
abstract: Septic shock remains a significant challenge for clinicians. Recent advances in cellular and molecular biology have significantly improved our understanding of its pathogenetic mechanisms. These improvements in understanding should translate to better care and improved outcomes for these patients.
authors.affiliation: Division of Critical Care Medicine, Department of Internal Medicine, Cooper University Hospital, Camden, NJ, USA. Okorie-Okorie@CooperHealth.edu
authors.forename: O Okorie
authors.initials: OO
authors.lastname: Nduka
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Parrillo
mesh_terms: D002477:Cells / Q000473:pathology; D006801:Humans; D018805:Sepsis / Q000503:physiopathology; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000503:physiopathology*