title: More, more, more: downregulation of a MK5-FoxO3a-mir34b/c pathway further increases c-Myc levels in colorectal cancer.
abstract: The c-Myc transcription factor has been shown to be central for colorectal carcinogenesis. In this issue of Molecular Cell, Kress and colleagues (Kress et al., 2011) identify an exciting new pathway that downregulates c-Myc translation which is lost in aggressive colorectal cancer.
authors.affiliation: Beatson Institute of Cancer Research, Switchback Road, Glasgow G611BD, UK.
authors.forename: Kevin
authors.initials: K
authors.lastname: Myant
authors.forename: Owen J
authors.initials: OJ
authors.lastname: Sansom