title: Renal Transplantation in HIV-Positive Recipients.
abstract: About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among HIV-infected patients. Traditionally, HIV infection has been considered an absolute contraindication to solid-organ transplantation. However, in the context of improved survival, the role for kidney transplantation among HIV-positive patients is currently being revisited. This article discusses long-term outcomes after kidney transplantation in the HAART era and management strategies for the HIV-positive kidney transplant recipient.
authors.affiliation: Division of Transplantation, Johns Hopkins Medical Institutions, 720 Rutland Avenue, Ross 765, Baltimore, MD, 21205, USA.
authors.forename: Jayme E
authors.initials: JE
authors.lastname: Locke
authors.forename: Dorry L
authors.initials: DL
authors.lastname: Segev