title: Efficacy of allopurinol in single daily dose.
abstract: Allopurinol 300 mg once daily was compared with allopurinol, 100 mg tid in 17 patients with gouty arthritis and/or gouty nephrolithiasis. Weekly serum uric acid levels showed small but statistically significant differences between dosage regimens in four patients. Two acute attacks of gouty arthritis occurred in two different patients during once daily dosing of the allopurinol. There were no side effects attributable to the once daily dosage regimen.
authors.forename: D
authors.initials: D
authors.lastname: Fraser
authors.forename: A H
authors.initials: AH
authors.lastname: Little
authors.forename: W R
authors.initials: WR
authors.lastname: Bartle