title: Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.
abstract: The use of non covalent supramolecular ligand-ligand and ligand-substrate interactions in transition metal-catalysed transformations is a new, rapidly emerging area of research. Non-covalent interactions between monodentate ligands such as hydrogen bonding, coordinative bonding, ion pairing, π-π interactions and the formation of inclusion compounds, have been shown to impart higher activity and chemo-, regio-, and stereoselectivity to the corresponding transition metal complexes in a number of catalytic applications. Analogously, supramolecular ligand-substrate interactions, and particularly hydrogen bonding, have been used to direct the regio- and stereochemistry of several metal-catalysed reactions. The catalytic systems relying on supramolecular interactions are generally capable of self-assembling from simpler components in the environment where catalysis is to take place, and are therefore very well-suited for combinatorial catalyst discovery strategies and high-throughput screening.
authors.affiliation: Università degli Studi dell'Insubria, Dipartimento di Scienze Chimiche e Ambientali, Via Valleggio 11, I-22100, Como, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Carboni
authors.forename: Cesare
authors.initials: C
authors.lastname: Gennari
authors.forename: Luca
authors.initials: L
authors.lastname: Pignataro
authors.forename: Umberto
authors.initials: U
authors.lastname: Piarulli