title: One case of Candidemia developed after surgery for tongue cancer in a young adult.
abstract: Candidemia is an opportunistic infection caused primarily by Candida albicans. We experienced a case of severe Candidemia that developed after surgical treatment for tongue cancer and required considerable labor to diagnose and to treat, though no particular immunodeficiency was seen before. The case was resistant to an antifungal agent, fluconazole, but was successfully treated with amphotericin B. Positive blood cultures, local wound culture, and increased β;-D-glucan were useful to diagnose the infection. In particular, gallium-67 scintigraphy was remarkably useful for the diagnosis and the evaluation of therapeutic effects in this case. Development of Candidemia following an oral and maxillofacial surgery is extremely rare among young adults, thus this case report serves to draw attention to the risk in oral and maxillofacial surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. ootsuru@is.icc.u-tokai.ac.jp
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Otsuru
authors.forename: Takayuki
authors.initials: T
authors.lastname: Aoki
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Ota
authors.forename: Kazunari
authors.initials: K
authors.lastname: Karakida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Masashi
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000472:pathogenicity; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000627:therapeutic use; D005710:Gallium Radioisotopes / Q000378:metabolism; D006801:Humans; D011183:Postoperative Complications; D011877:Radionuclide Imaging; D014062:Tongue Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D005710:Gallium Radioisotopes; D000666:Amphotericin B; D015725:Fluconazole