title: Rapid murine mixed lymphocyte cultures assessed by emergence of T-cell insulin receptors.
abstract: Murine T lymphocytes incubated in a mixed lymphocyte culture with allogeneic lymphocytes incompatible for theH-2 region or subregions thereof rapidly develop insulin receptors. In contrast, T cells cultured with syngeneic orH-2- andMlslocus compatible cells do not develop insulin-binding sites. The emergence of insulin receptors is probably an early premitotic event.
authors.affiliation: Department of Medicine, Harvard Medical School, Peter Bent Brigham Hospital, USA.
authors.forename: T B
authors.initials: TB
authors.lastname: Strom
authors.forename: J H
authors.initials: JH
authors.lastname: Helderman
authors.forename: R M
authors.initials: RM
authors.lastname: Williams