title: Angioplasmocellular hyperplasia: a clinicopathologic study of 10 patients.
abstract: BACKGROUND
  Angioplasmocellular hyperplasia is rarely reported.
  
  
  OBJECTIVE
  The purpose of this study is to describe and analyze the clinicopathologic features of angioplasmocellular hyperplasia.
  
  
  METHODS
  The records of 10 patients (mean age, 45 years; range, 17 to 71 years) with characteristic histologic features of angioplasmocellular hyperplasia were reviewed and the histopathologic findings, clinical features, and medical histories analyzed. Formalin-fixed, paraffin-embedded specimens were examined by immunohistochemical staining.
  
  
  RESULTS
  The most common clinical appearance was a single nodule with an erythematous rim. Histologically, the inflammatory infiltrate comprised mainly polyclonal plasma cells. There was vascular proliferation of capillaries and venules with varying numbers of plump endothelial cells. There were no definite predisposing factors.
  
  
  CONCLUSIONS
  The number of cases was limited and all patients were Asian.
  
  
  CONCLUSIONS
  Angioplasmocellular hyperplasia had a distinct clinical appearance characterized by its inflammatory rim. The nature of the infiltrating cells and distribution of blood vessels indicates that it is a form of reactive plasmocytic inflammatory vascular hyperplasia.
authors.affiliation: Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Pa-Fan
authors.initials: PF
authors.lastname: Hsiao
authors.forename: Yu-Hung
authors.initials: YH
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003872:Dermatitis / Q000473:pathology*; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000473:pathology*