title: Chronic interstitial nephritis in an HIV type-1-infected patient receiving ritonavir-boosted atazanavir.
abstract: Here, we report a case of chronic granulomatous tubulo-interstitial nephritis related to atazanavir crystals in a HIV type-1-infected patient. Renal function in this patient was partially recovered after atazanavir withdrawal and steroid therapy. Many reports have described atazanavir-associated urolithiasis, but this is the first case that describes chronic granulomatous nephropathy.
authors.affiliation: Néphrologie-Transplantation, Hôpital Saint-Louis, Paris, France. denis.viglietti@wanadoo.fr
authors.forename: Denis
authors.initials: D
authors.lastname: Viglietti
authors.forename: Jérôme
authors.initials: J
authors.lastname: Verine
authors.forename: Nathalie
authors.initials: N
authors.lastname: De Castro
authors.forename: Anne
authors.initials: A
authors.lastname: Scemla
authors.forename: Michel
authors.initials: M
authors.lastname: Daudon
authors.forename: Denis
authors.initials: D
authors.lastname: Glotz
authors.forename: Evangeline
authors.initials: E
authors.lastname: Pillebout
mesh_terms: D000352:Africa, Northern / Q000208:ethnology; D000069446:Atazanavir Sulfate; D003460:Crystallization; D004359:Drug Therapy, Combination / Q000009:adverse effects*; D005602:France; D006105:Granulomatous Disease, Chronic / Q000139:chemically induced* / Q000503:physiopathology; D015658:HIV Infections / Q000188:drug therapy / Q000473:pathology; D017320:HIV Protease Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000503:physiopathology; D009842:Oligopeptides / Q000008:administration & dosage / Q000009:adverse effects*; D011725:Pyridines / Q000008:administration & dosage / Q000009:adverse effects*; D019438:Ritonavir / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D017320:HIV Protease Inhibitors; D009842:Oligopeptides; D011725:Pyridines; D000069446:Atazanavir Sulfate; D019438:Ritonavir