title: HATs on for drug resistance.
abstract: Mutations in the human cytomegalovirus UL27 gene confer resistance to an inhibitor of the viral protein kinase UL97. Reitsma and colleagues (2011) demonstrate that UL27 destabilizes the Tip60 histone acetyltransferase, setting forth intriguing new mechanisms for antiviral drug resistance and for viral regulation of the cell cycle.
authors.affiliation: Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, 71130, USA. jkamil@lsuhsc.edu
authors.forename: Jeremy P
authors.initials: JP
authors.lastname: Kamil
authors.forename: Donald M
authors.initials: DM
authors.lastname: Coen