title: [Lymphogranuloma venereum proctocolitis in men with HIV-1 infection].
abstract: BACKGROUND
  We present a series of 15 cases with lymphogranuloma venereum (LGV) with the aim of evaluating the response to a 21-day oral course of doxycycline (100mg twice daily).
  
  
  METHODS
  It is an observational study where we describe a series of cases with LGV diagnosed in the Hospital Germans Trias i Pujol's HIV Unit between March 2008 and April 2009.
  
  
  RESULTS
  All our patients were HIV infected men who had sex with men with proctitis in 80% of the cases. In all of them Chlamydia trachomatis was determined by PCR on rectal swab specimens, with a negative result after 21 days of treatment with doxycycline. Serovar L2 was confirmed in all the specimens with the reverse hybridization technique.
  
  
  CONCLUSIONS
  A high index of clinical suspicion is the mainstay to the early diagnosis of LGV since the clinical presentation remains unspecific. The treatment with doxycycline eradicates C. trachomatis in HIV patients with LGV.
authors.affiliation: Servicio de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España. evahmu@hotmail.com
authors.forename: Eva
authors.initials: E
authors.lastname: Heras
authors.forename: Josep M
authors.initials: JM
authors.lastname: Llibre
authors.forename: Elisa
authors.initials: E
authors.lastname: Martró
authors.forename: Jordi
authors.initials: J
authors.lastname: Casabona
authors.forename: Raquel
authors.initials: R
authors.lastname: Martin-Iguacel
authors.forename: Raquel
authors.initials: R
authors.lastname: Martín
authors.forename: Guillem
authors.initials: G
authors.lastname: Sirera
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002692:Chlamydia trachomatis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D015897:Comorbidity; D003952:Diagnostic Imaging; D004318:Doxycycline / Q000627:therapeutic use; D006069:Gonorrhea / Q000453:epidemiology / Q000382:microbiology; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D011350:Proctocolitis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D012007:Rectum / Q000382:microbiology; D012725:Sexual Behavior; D013030:Spain / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline