title: [NVB and DDP combination chemotherapy in the treatment of advanced non-small cell lung cancer].
abstract: BACKGROUND
  To evaluate the clinical effect and toxicity of NVB and DDP combination chemotherapy in the treatment of advanced non-small cell lung cancer.
  
  
  METHODS
  All 52 patients were treated with NP regimen: NVB 25 mg/m² iv, D1, D8; DDP 80 mg/m² iv, D1. The regimen was repeated every 3 weeks, tumor assessment was done after 2 cycles.
  
  
  RESULTS
  There were 2 complete responses (CR) and 26 partial responses (PR). The overall responses rate (CR+PR) was 53.8%, and the main toxicity was leucopenia, nause, vomiting and phlebitis.
  
  
  CONCLUSIONS
  The NP regimen is effective in the treatment of advanced non-small cell lung cancer, the toxicity is well tolerated. Hence the regimen can be regarded as first-line regimen of advanced non-small cell lung cancer.
authors.affiliation: Internal Medicine, Hubei Cancer Hospital, Wuhan, Hubei 430079, P.R.China.
authors.forename: Hui
authors.initials: H
authors.lastname: Jiang
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Fan
authors.forename: Ding
authors.initials: D
authors.lastname: Yu