title: Pneumonia in patients with novel influenza A (H1N1) virus in Southeastern Turkey.
abstract: The objective of this study was to describe the clinical characteristics and the radiological and laboratory findings of the hospitalised patients who had novel, laboratory-confirmed, swine-origin influenza A virus (S-OIV) infection with pneumonia. Between October and December 2009, 56 patients hospitalised for pneumonia who were tested for S-OIV infection were retrospectively evaluated. Thirty-three patients had positive S-OIV infections. In addition, 23 of the 56 patients who had negative test results for S-OIV infection were compared with the positive group. The mortality rate amongst the patients with S-OIV infection was 24.2%. Of the 33 patients, 42.4% had at least one underlying medical condition and 4 (12%) patients were pregnant or postpartum. Fourteen patients (42.4%) with S-OIV infection were followed up in an intensive care unit. The most common symptom was dyspnea. The mean peak body temperature during hospital stay (39.42 ± 0.70) was higher in this group than in the negative group (38.51 ± 1.05) (p = 0.001). Thrombocytopenia, increased creatine kinase and elevated lactate dehydrogenase levels were statistically significant. Bilateral infiltration was more common in the patients with S-OIV infection. Although some laboratory, radiological and clinical data show a significant difference between the patients with S-OIV pneumonia and the negative group, each patient presenting with signs of pneumonia during pandemia should be tested for Influenza A.
authors.affiliation: Department of Pulmonology, Zonguldak Karaelmas University Medical Faculty, Zonguldak, Turkey. tacettinornek@yahoo.com
authors.forename: Tacettin
authors.initials: T
authors.lastname: Ornek
authors.forename: Funda Demirtaş
authors.initials: FD
authors.lastname: Yalçın
authors.forename: Selami
authors.initials: S
authors.lastname: Ekin
authors.forename: Saban
authors.initials: S
authors.lastname: Yalçın
authors.forename: Mücahit
authors.initials: M
authors.lastname: Yemişen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015897:Comorbidity; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000453:epidemiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult