title: Clinical features and outcome of children and adolescents hospitalized with influenza A (H1N1) virus infection compared with flu-like symptoms and negative rapid tests for influenza A (H1N1) admitted in the same period of time.
abstract: This report describes the clinical features and outcome of 61 pediatric hospitalized patients with influenza-like infection. Fever, cough and respiratory distress were the most common symptoms of the infection. Fifteen patients presented positive RT-PCR results for influenza A (H1N1). The group with positive results was compared with the negative one. The main significant difference was antibiotic usage and the need of mechanical ventilation in the patients with H1N1-virus infection. Among the 11 patients who required intensive care due to respiratory failure, 3 from the positive group died and none from the negative group.
authors.affiliation: Pediatric Department and State Hospital of Sumaré, Faculty of Medical Science, Clinical Hospital, State University of Campinas, São Paulo, Brazil.
authors.forename: Antoni T
authors.initials: AT
authors.lastname: Tresoldi
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Pereira
authors.forename: Andrea M A
authors.initials: AM
authors.lastname: Fraga
authors.forename: Mariana T N
authors.initials: MT
authors.lastname: Romaneli
authors.forename: Cristiane C
authors.initials: CC
authors.lastname: Omae
authors.forename: Emilio C E
authors.initials: EC
authors.lastname: Baracat
authors.forename: Marcelo C
authors.initials: MC
authors.lastname: Reis
authors.forename: Maria L F
authors.initials: ML
authors.lastname: Miranda
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003422:Critical Care; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D007902:Length of Stay; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use; D012121:Respiration, Artificial; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D053139:Oseltamivir