title: Pregnancy after modified natural cycle IVF: case report of a young patient with elevated FSH levels and male factor infertility.
abstract: BACKGROUND
  Although the first pregnancy obtained by IVF was in a natural cycle, this method was soon abandoned in favour of gonadotropin-stimulated protocols to improve pregnancy rates. In women who are poor responders to ovarian stimulation, the use of a natural cycle may provide a good alternative for achieving a pregnancy, although there is limited information on the success of modified natural cycle in vitro fertilization (MNC-IVF) in young patients with poor ovarian reserve.
  
  
  METHODS
  A 35-year-old woman with significantly elevated FSH levels (consistently > 30 IU/L) but regular menses, and with severe male factor infertility, conceived using MNC-IVF with intracytoplasmic sperm injection (ICSI).
  
  
  CONCLUSIONS
  This case demonstrates that younger patients (aged 35 or under) with elevated basal serum FSH levels and regular menses can be offered MNC-IVF as an option prior to considering oocyte donation when a secondary cause of infertility necessitates IVF or ICSI.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Toronto Toronto ON.
authors.forename: Claire
authors.initials: C
authors.lastname: Jones
authors.affiliation: Division of Reproductive Endocrinology and Infertility, Centre for Fertility and Reproductive Health, Mt Sinai Hospital Toronto ON.
authors.forename: Kimberly
authors.initials: K
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy*; D008297:Male; D008597:Menstrual Cycle; D009845:Oligospermia; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005640:Follicle Stimulating Hormone