title: Removable directing groups in organic synthesis and catalysis.
abstract: Directing groups have been widely used in recent years to achieve control over all aspects of reaction selectivity in a wide range of transformations involving transition-metal catalysis and organometallic reagents. In cases when the existing functional group within a substrate is unsuited to achieve efficient intramolecular delivery of a reagent or catalyst, the specific introduction of an appropriately designed removable reagent-directing group can be a solution to this problem. In this Review we give an overview of the state of the art in this area, including the stoichiometric and catalytic use of directing groups.
authors.affiliation: Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104 Freiburg i. Brsg., Germany.
authors.forename: Géraldine
authors.initials: G
authors.lastname: Rousseau
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit