title: [In silico pharmacology of Chinese herbs for chronic kidney diseases].
abstract: Tonifying herbs and evil expelling herbs of traditional Chinese medicine (TCM) for chronic kidney diseases in molecular level were studied by computer aided drug design, including analysis of molecular similarity, predictive ADME simulation and predictive toxic simulation. It was found that this technology could distinguish the structure diversity of compounds from TCM, and screen the lead compounds rapidly.
authors.affiliation: Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510106, China. zhuwei9201@163.com
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.forename: Dinghong
authors.initials: D
authors.lastname: Wu
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Qiu
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
mesh_terms: D002908:Chronic Disease / Q000628:therapy; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal