title: Steroidal alkaloid saponins and steroidal saponins from Solanum surattense.
abstract: A rare 16β-H steroidal alkaloid saponin (1), an avenacoside-type saponin (2), two steroidal saponins (4, 5), one revised-structure steroidal saponin (3) and six known compounds (6-11) were isolated from aerial parts of Solanum surattense Burm. f. Their structures were established on the basis of physical data, as well as by using spectroscopic (HRESIMS, 1D and 2D NMR), and chemical analysis methods. Compounds 1 and 11 showed cytotoxicity against A549 cell line with IC(50) values of 20.3 and 15.7μM, respectively.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Lu
authors.forename: Jianguang
authors.initials: J
authors.lastname: Luo
authors.forename: Lingyi
authors.initials: L
authors.lastname: Kong
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D006801:Humans; D020128:Inhibitory Concentration 50; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D032322:Solanum / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D012503:Saponins