title: Implementation of asymmetric yielding in case-specific finite element models improves the prediction of femoral fractures.
abstract: Although asymmetric yielding in bone is widely shown in experimental studies, previous case-specific non-linear finite element (FE) studies have mainly adopted material behaviour using the Von Mises yield criterion (VMYC), assuming equal bone strength in tension and compression. In this study, it was verified that asymmetric yielding in FE models can be captured using the Drucker-Prager yield criterion (DPYC), and can provide better results than simulations using the VMYC. A sensitivity analysis on parameters defining the DPYC (i.e. the degree of yield asymmetry and the yield stress settings) was performed, focusing on the effect on bone failure. In this study, the implementation of a larger degree of yield asymmetry improved the prediction of the fracture location; variations in the yield stress mainly affected the predicted failure force. We conclude that the implementation of asymmetric yielding in case-specific FE models improves the prediction of femoral bone strength.
authors.affiliation: Orthopaedic Research Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. l.derikx@orthop.umcn.nl
authors.forename: Loes C
authors.initials: LC
authors.lastname: Derikx
authors.forename: Roeland
authors.initials: R
authors.lastname: Vis
authors.forename: Timo
authors.initials: T
authors.lastname: Meinders
authors.forename: Nico
authors.initials: N
authors.lastname: Verdonschot
authors.forename: Esther
authors.initials: E
authors.lastname: Tanck
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005264:Femoral Fractures; D020342:Finite Element Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged