title: Phenomenological model of laser-tissue interaction with application to Benign Prostatic Hyperplasia (BPH) simulation.
abstract: Laser-tissue interaction is a multi-physics phenomenon not yet mathematically describable and computationally predictable. It is a challenge to model the laser-tissue interaction for real time laser Benign Prostatic Hyperplasia (BPH) simulation which requires the laser-tissue interaction model to be computationally efficient and accurate. Under the consideration and enforcement of the thermodynamic first law and treating the laser-tissue interaction as a gray-box, utilizing the sensitivity analysis of some key parameters that will affect the laser intensity on the tissue surface with respect to the tissue vaporization rate, a phenomenological model of laser-tissue interaction is developed. The developed laser-tissue interaction model has been implemented for a laser BPH simulator and achieves real time performance (more than 30 frames per second). The model agrees well with the available experimental data.
authors.affiliation: Center for Research in Education and Simulation Technologies (CREST), University of Minnesota, Minneapolis, MN, USA. xiangmin.zhou@gmail.com
authors.forename: Xiangmin
authors.initials: X
authors.lastname: Zhou
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.forename: Yunhe
authors.initials: Y
authors.lastname: Shen
authors.forename: Dan
authors.initials: D
authors.lastname: Burke
authors.forename: Vamsi
authors.initials: V
authors.lastname: Konchada
authors.forename: Robert
authors.initials: R
authors.lastname: Sweet
mesh_terms: D003198:Computer Simulation; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008954:Models, Biological; D011468:Prostatectomy / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome