title: Choroidal neovascularization associated with coloboma of the choroid: a series of three cases.
abstract: Choroidal neovascularization (CNV) is a rare complication associated with coloboma of the choroid. We describe three cases of coloboma choroid where there was loss of vision due to CNV development at the edge of the coloboma. One was managed by photodynamic therapy alone and two were managed by a combination of reduced fluence PDT and intravitreal bevacizumab. Significantly we noted that one treatment session was sufficient to achieve regression of the CNV and improvement in visual acuity.
authors.affiliation: Shri Bhagawan Mahavir Vitreoretinal Service, Sankara Nethralaya, 18 College Road, Chennai - 600 006, India. drmuna@snmail.org
authors.forename: Muna
authors.initials: M
authors.lastname: Bhende
authors.forename: G
authors.initials: G
authors.lastname: Suganeswari
authors.forename: Lingam
authors.initials: L
authors.lastname: Gopal
authors.forename: Pramod S
authors.initials: PS
authors.lastname: Bhende
authors.forename: Lekha
authors.initials: L
authors.lastname: Gopal
authors.forename: Chetan
authors.initials: C
authors.lastname: Rao
mesh_terms: D000328:Adult; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage*; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D002829:Choroid / Q000002:abnormalities*; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D003103:Coloboma / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D055815:Young Adult
chemical_list: D020533:Angiogenesis Inhibitors; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab