title: Gold-catalyzed direct amination of arenes with azodicarboxylates.
abstract: Gold(III) chloride catalyzed direct amination of arenes with azodicarboxylates was developed. The new catalytic system was active to a broad range of substrates, and the reaction was carried out under mild conditions. It represents the first catalytic system for the direct amination of electron-deficient arenes with azodicarboxylates to the best of our knowledge. This reaction provides an important approach for the synthesis of heterocyclic compounds in pharmaceutical and chemical industries.
authors.affiliation: Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, the Nanos, Singapore 138669.
authors.forename: Liuqun
authors.initials: L
authors.lastname: Gu
authors.forename: Boon Siong
authors.initials: BS
authors.lastname: Neo
authors.forename: Yugen
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000586:Amination; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003998:Dicarboxylic Acids / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D001391:Azo Compounds; D003998:Dicarboxylic Acids; D006046:Gold