title: Comparing the effectiveness of a clinical registry and a clinical data warehouse for supporting clinical trial recruitment: a case study.
abstract: This paper reports a case study comparing the relative efficiency of using a Diabetes Registry or a Clinical Data Warehouse to recruit participants for a diabetes clinical trial, TECOS. The Clinical Data Warehouse generated higher positive predictive accuracy (31% vs. 6.6%) and higher participant recruitment than the Registry (30 vs. 14 participants) in a shorter time period (59 vs. 74 working days). We identify important factors that increase clinical trial recruitment efficiency and lower cost.
authors.affiliation: Department of Biomedical Informatics;
authors.forename: Chunhua
authors.initials: C
authors.lastname: Weng
authors.forename: J Thomas
authors.initials: JT
authors.lastname: Bigger
authors.forename: Linda
authors.initials: L
authors.lastname: Busacca
authors.forename: Adam
authors.initials: A
authors.lastname: Wilcox
authors.forename: Asqual
authors.initials: A
authors.lastname: Getaneh
mesh_terms: D003920:Diabetes Mellitus; D006801:Humans; D018579:Patient Selection; D012042:Registries