title: Terahertz imaging of biological tissues.
abstract: A reflective THz imaging system sensitive to small variations in water concentrations has been developed. Biological tissues such as skin, eyes and teeth were imaged to ascertain the systems response to tissue hydration. Difference in water concentrations translated to contrast in the THz images. Contrast was also seen in THz images of skin cancer and burns suggesting the potential diagnostic capability of THz imaging system in clinical settings. All specimens analyzed were freshly excised ex-vivo tissues. These encouraging preliminary results have motivated us to explore the in vivo potential of our imaging system.
authors.affiliation: Center for Advanced Surgical and Interventional Technology (CASIT), Department of Surgery, University of California, Los Angeles, CA, USA.
authors.forename: Priyamvada
authors.initials: P
authors.lastname: Tewari
authors.forename: Zachary D
authors.initials: ZD
authors.lastname: Taylor
authors.forename: David
authors.initials: D
authors.lastname: Bennett
authors.forename: Rahul S
authors.initials: RS
authors.lastname: Singh
authors.forename: Martin O
authors.initials: MO
authors.lastname: Culjat
authors.forename: Colin P
authors.initials: CP
authors.lastname: Kealey
authors.forename: Jean Pierre
authors.initials: JP
authors.lastname: Hubschman
authors.forename: Shane
authors.initials: S
authors.lastname: White
authors.forename: Alistair
authors.initials: A
authors.lastname: Cochran
authors.forename: Elliott R
authors.initials: ER
authors.lastname: Brown
authors.forename: Warren S
authors.initials: WS
authors.lastname: Grundfest
mesh_terms: D000465:Algorithms; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055069:Terahertz Imaging / Q000379:methods*