title: Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity.
abstract: UV-visible titrations, (1)H NMRD experiments and molecular docking studies show that emissive anthraquinone appended dimetallic lanthanide complexes bind to DNA. The strength of binding and the observed relaxivity behaviour depend on the nature of the substituted anthraquinone core.
authors.affiliation: School of Chemistry, Main Building, Cardiff University, Cardiff CF10 3AT, Cymru/Wales.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Jones
authors.forename: Angelo J
authors.initials: AJ
authors.lastname: Amoroso
authors.forename: I Mihaela
authors.initials: IM
authors.lastname: Dorin
authors.forename: Giacomo
authors.initials: G
authors.lastname: Parigi
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Ward
authors.forename: Niklaas J
authors.initials: NJ
authors.lastname: Buurma
authors.forename: Simon J A
authors.initials: SJ
authors.lastname: Pope
mesh_terms: D000880:Anthraquinones / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D005682:Gadolinium / Q000737:chemistry*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009942:Organometallic Compounds / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D000880:Anthraquinones; D009942:Organometallic Compounds; D014867:Water; D004247:DNA; D005682:Gadolinium