title: Towards treatment planning for the embolization of arteriovenous malformations of the brain: intranidal hemodynamics modeling.
abstract: This paper presents a patient-derived model for the simulation of the hemodynamics of arteriovenous malformations of the brain (BAVM). This new approach is a step toward the simulation of the outcome of the embolization of the BAVM during treatment planning. More specifically, two aspects of the planning are pursued: simulation of the change of blood flow in the brain vasculature after the blocking of the malformation and simulation of the transport of the embolic liquid. The method we propose is tested on 3 BAVM cases of varying complexity. Twenty two out of 24 main BAVM flow paths have been identified well by simulation.
authors.affiliation: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, OX3 7DQ, UK.
authors.forename: Piotr
authors.initials: P
authors.lastname: Orlowski
authors.forename: Fahmi
authors.initials: F
authors.lastname: Al-Senani
authors.forename: Paul
authors.initials: P
authors.lastname: Summers
authors.forename: James
authors.initials: J
authors.lastname: Byrne
authors.forename: J Alison
authors.initials: JA
authors.lastname: Noble
authors.forename: Yiannis
authors.initials: Y
authors.lastname: Ventikos
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004621:Embolization, Therapeutic / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy*; D008955:Models, Cardiovascular; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014783:Viscosity