title: Efficacy of a pit and fissure sealant in arresting dentin non-cavitated caries: a 1-year follow-up, randomized, single-blind, controlled clinical trial.
abstract: OBJECTIVE
  To evaluate the efficacy of conservative treatment of dentin non-cavitated caries using a resin-based fluoride-containing pit and fissure sealant.
  
  
  METHODS
  In this controlled clinical trial, 60 teeth with clinically non-cavitated occlusal caries radiographically located beneath the enamel-dentin junction (radiolucent area) were selected among patients presenting a moderate to high caries risk. The teeth were randomly divided into two groups of 30 teeth each: an experimental group receiving an application of Fluorshield (Dentsply) sealant and a control group not submitted to any clinical intervention. Caries progression was monitored by clinical and radiographic examination at 4-month intervals over a period of 1 year. In addition, marginal integrity of the sealant was evaluated in the experimental group.
  
  
  RESULTS
  Clinical and radiographic caries progression was significantly more frequent in control teeth when compared to the experimental group (P < 0.05).
authors.affiliation: Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Natal/RN, Brazil. boniek.castillo@gmail.com
authors.forename: Boniek Castillo Dutra
authors.initials: BC
authors.lastname: Borges
authors.forename: Giordano Bruno Paiva
authors.initials: GB
authors.lastname: Campos
authors.forename: Ana Daniela Silva
authors.initials: AD
authors.lastname: da Silveira
authors.forename: Kenio Costa
authors.initials: KC
authors.lastname: de Lima
authors.forename: Isauremi Vieira de Assunção
authors.initials: IV
authors.lastname: Pinheiro
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D003731:Dental Caries / Q000000981:diagnostic imaging / Q000517:prevention & control*; D003804:Dentin / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008963:Molar; D010895:Pit and Fissure Sealants / Q000627:therapeutic use*; D011859:Radiography; D016037:Single-Blind Method; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D010895:Pit and Fissure Sealants