title: ACE inhibitor-induced angioedema: a case report and review of current management.
abstract: Angiotensin-converting enzyme inhibitors (ACEIs) have replaced diuretics and Β-blockers as first-line agents for treating hypertension. Cough is a recognised side effect of ACEI treatment, and because of this, patients often have their medication changed to an angiotensin II receptor blocker (AIIRB). Both ACEIs and AIIRBs are associated with angioedema. We present a case of a late-onset angioedema associated with pyrexia and raised levels of inflammatory markers. We also discuss the causes and treatments of angioedema, and current controversies surrounding ACEIs and AIIRBs and their relation to anaphylaxis and angioedema.
authors.affiliation: Nepean Hospital, Sydney, NSW, Australia.
authors.forename: Nina
authors.initials: N
authors.lastname: Kloth
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Lane
mesh_terms: D000368:Aged; D000799:Angioedema / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D015994:Incidence; D015201:Meta-Analysis as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors