title: [Clinical and biochemical syndromes of cadmium-induced acute porphyrinopathy].
abstract: OBJECTIVE
  To study the specific features of porphyrin metabolic disturbances in cadmium poisoning.
  
  
  METHODS
  The paper describes a patient who has developed clinical and biochemical syndromes of acute porphyrinopathy after exposure to cadmium-containing paint the vapors. The levels of delta-aminolevulinic acid, porphobilinogen, coproporphyrin, and uroporphyrin in urine and those of coproporphyrin and protoporphyrin in feces were measured. The concentrations of lead, cadmium, and copper were determined in whole blood and urine; selective screening of amino acids for hereditary metabolic diseases was made.
  
  
  RESULTS
  The clinical signs of acute porphyrinopathy developed in the patient mimicked those of acute porphyries known by the current classification. The biochemical syndrome more corresponded to lead poisoning. However, the blood and urinary lead levels were not greater than the normal values, but the blood showed a 4-fold increase in cadmium, which seemed to induce porphyrin dysmetabolism.
authors.forename: A B
authors.initials: AB
authors.lastname: Krivosheev
authors.forename: B N
authors.initials: BN
authors.lastname: Krivosheev
authors.forename: E L
authors.initials: EL
authors.lastname: Poteriaeva
authors.forename: L V
authors.initials: LV
authors.lastname: Parulikova
authors.forename: O I
authors.initials: OI
authors.lastname: Mikhaĭlenko
mesh_terms: D000328:Adult; D002105:Cadmium Poisoning / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000628:therapy / Q000652:urine; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D011164:Porphyrias / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy / Q000652:urine; D011166:Porphyrins / Q000097:blood / Q000378:metabolism* / Q000652:urine; D016896:Treatment Outcome
chemical_list: D011166:Porphyrins