title: Erdheim-Chester disease: a histiocytic disorder more than skin deep.
abstract: Erdheim-Chester disease is a rare potentially malignant systemic non-Langerhans cell histiocytosis. Although classically described in the pulmonary system and long bones, cutaneous involvement has been chronicled in 2 previous case reports. Herein, we describe a single systemic case afflicting an elderly man with synchronous multifocal cutaneous disease. The previous literature and pertinent differential diagnosis will be discussed.
authors.affiliation: Department of Pathology, University of South Florida, Tampa, FL, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Skinner
authors.forename: Michale
authors.initials: M
authors.lastname: Briant
authors.forename: M B
authors.initials: MB
authors.lastname: Morgan
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000008:administration & dosage; D031249:Erdheim-Chester Disease / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016898:Interferon-alpha / Q000008:administration & dosage; D008297:Male; D011878:Radiotherapy; D012871:Skin Diseases / Q000473:pathology* / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D016898:Interferon-alpha; D016572:Cyclosporine