title: Recurrent bilateral dermatofibrosarcoma protuberans of eyelids.
abstract: A 26-year-old man had a history of multiple nodules involving the upper and lower eyelids bilaterally, for which he had undergone wide local excision along with eyelid reconstruction. Three years later, he presented to the authors with recurrence of the tumor masses. Tumor debulking surgery was performed bilaterally, with eyelid reconstructive surgery. Histopathology of the excised mass showed spindle-shaped cells in the dermis, which were arranged in a storiform pattern. Immunohistochemically, the tumor expressed vimentin diffusely and CD-34 focally. Histopathologic findings of storiform pattern of tumor cells and positive immunohistochemical stains for CD-34 led to the diagnosis of dermatofibrosarcoma protuberans. The clinical course was marked by repeated local recurrences following multiple debulking procedures. Local control could not be achieved in this case and at last follow up, the tumor was surgically unresectable.
authors.affiliation: Oculoplastic and Paediatric Ophthalmology Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. bhavna2424@hotmail.com
authors.forename: Bhavna
authors.initials: B
authors.lastname: Chawla
authors.forename: Neelam
authors.initials: N
authors.lastname: Pushker
authors.forename: Seema
authors.initials: S
authors.lastname: Sen
authors.forename: Mandeep S
authors.initials: MS
authors.lastname: Bajaj
authors.forename: Noornika
authors.initials: N
authors.lastname: Khuraijam
authors.forename: Supriyo
authors.initials: S
authors.lastname: Ghose
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D018223:Dermatofibrosarcoma / Q000737:chemistry / Q000473:pathology / Q000601:surgery*; D005142:Eyelid Neoplasms / Q000737:chemistry / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor