title: Molecular Methods for Detecting Ulcerogenic Strains of H. pylori.
abstract: Certain nonconserved genotypic and phenotypic characteristics of H. pylori are associated with increased risk of peptic ulceration in the human host. These characteristics can be divided into two groups: first, those relating to vacuolating cytotoxin activity (1,2), and differences in the gene encoding the cytotoxin, vacA (3); second, those relating to the cytotoxin-associated gene, cagA (4,5).
authors.affiliation: Division of Gastroenterology and Institute of Infections and Immunity, University Hospital, Nottingham, UK.
authors.forename: J C
authors.initials: JC
authors.lastname: Atherton