title: Prognostic value of lymph node involvement in ovarian serous borderline tumors.
abstract: OBJECTIVE
  This study was conducted to evaluate the prognosis value of lymph node involvement (LN positive) lymph node involvement for borderline ovarian tumor (BOT).
  
  
  METHODS
  This was a retrospective study on 49 patients treated at our institution for advanced-stage serous BOT (International Federation of Gynecology and Obstetrics [FIGO] III or IV). Pathological characteristics and survival were compared according to the lymph node status. The same analysis was performed on 1503 patients of the Surveillance, Epidemiology, and End Results (SEER) database.
  
  
  RESULTS
  In our institution, 14 patients were LN positive. Eight patients have been upstaged after lymph node dissection. No patient has died during follow-up (median 53 months). LN positivity was not associated with recurrence. In the SEER registry, 93 patients (6.2%) had LN positivity. These patients were younger and with more advanced local extension. Survival curves were similar after adjustment for FIGO stage.
  
  
  CONCLUSIONS
  Lymph node involvement does not appear as a prognosis factor for advanced-stage BOT.
authors.affiliation: Department of Gynecologic Surgery, Institut Gustave Roussy, Villejuif, France.
authors.forename: Benedicte
authors.initials: B
authors.lastname: Lesieur
authors.forename: Aminata
authors.initials: A
authors.lastname: Kane
authors.forename: Pierre
authors.initials: P
authors.lastname: Duvillard
authors.forename: Sebastien
authors.initials: S
authors.lastname: Gouy
authors.forename: Patricia
authors.initials: P
authors.lastname: Pautier
authors.forename: Catherine
authors.initials: C
authors.lastname: Lhommé
authors.forename: Philippe
authors.initials: P
authors.lastname: Morice
authors.forename: Catherine
authors.initials: C
authors.lastname: Uzan
mesh_terms: D000328:Adult; D018284:Cystadenocarcinoma, Serous / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies