title: Outer membrane protein purification.
abstract: The major outer membrane proteins (OMPs) from Neisseria meningitidis, which are expressed at high levels, are subdivided in five classes based on molecular weight (1,2) (see Table 1). Table 1 Major Meningococcal Outer-Membrane Proteins Outer-membrane proteins Name Molecular maass Function/characteristics Class 1 PorA 44-47 kDa Porin Class 2/3 PorB 37-42 kDa Porin Class 4 Rmp Reductionmodifiableprotein, unknown Class 5 Opa 26-30 kDa Adhesion,opacity protein Opc 25 kDa Invasion, opacity protein Iron-regulated proteins Mirp 37 kDa Iron acquisition (?);majoriron-regulatedprotein FrpB 70 kDa Ferric enterobactin receptor (also FetA) Adapted from ref. (1).
authors.affiliation: Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht, The Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: Arigita
authors.forename: W
authors.initials: W
authors.lastname: Jiskoot
authors.forename: M R
authors.initials: MR
authors.lastname: Graaf
authors.forename: G F
authors.initials: GF
authors.lastname: Kersten