title: Genetics of depression: an overview of the current science.
abstract: Most psychiatric disorders, including major depressive disorder (MDD), are known to involve complex interactions between genetic and environmental influences that impact the development and severity of symptomatology. Health care practitioner competencies have been expanded to include application of genetic knowledge in mental health. Yet this information is difficult to decipher and apply. To assist with these challenges, this article synthesizes recent literature related to the genetics of MDD and illustrates the genetic pathways for major depression.
authors.affiliation: Wichita State University, School of Nursing, Wichita, Kansas, USA. betty.elder@wichita.edu
authors.forename: Betty L
authors.initials: BL
authors.lastname: Elder
authors.forename: Victoria
authors.initials: V
authors.lastname: Mosack
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D003865:Major Depressive Disorder / Q000188:drug therapy / Q000235:genetics* / Q000451:nursing* / Q000503:physiopathology; D004200:Diseases in Twins / Q000235:genetics / Q000451:nursing; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D009434:Neural Pathways / Q000187:drug effects / Q000503:physiopathology; D018377:Neurotransmitter Agents / Q000502:physiology
chemical_list: D000928:Antidepressive Agents; D018377:Neurotransmitter Agents