title: [The characteristics of various forms of complicated surgery infections of the diabetic foot syndrome and their antibacterial treatment].
abstract: In case of neuropathic forms, infection is the cause of tissue nekros, while - in case of neuroischemic forms, it's critical ischemia. Antibacterial therapy is present in all cases of neuroischemic form, not dependent on the signs of infection, Though, in case of neuropathic forms, a course of antibiotics is prescribed only in case of the attachment of infection. Infected neuroischemic ulcer is characterized of acube development (infection+ischemia), unlike infections neuropathic, ulces. The researches showed that 42 patients (40%) suffered from neuropathic form and 63(60%) - from neuroischemic form. In purulent zones anaerobic flora was revealed in 77.3%, aerobic flora - 17.7%, the rise of microflora was not indicated in 5% of cases. Most often, with 43.6% St. aureus was found out, and from the association of microbes - st. aureus + Str. pyogenes - 8.7%. Was the level of bacterial pollution and varied from 105 to 10(12). The highest sensibility was shown towards Tienam (98.9%). The most acceptable and productive form of treatment turned our to be the following combination phtorchinolyns+aminoglycosides. Out of 105 patients 34 amputations were done + 6 tall, 10 large (more than a half) and 18 small (up to the middle of the foot). In 71 cases we successfully managed to stop infections processes and get rid of amputations.
authors.affiliation: Tbilisi State Medical University, Institute of Critical Medicine, Georgia.
authors.forename: A
authors.initials: A
authors.lastname: Kistauri
authors.forename: G
authors.initials: G
authors.lastname: Devidze
authors.forename: M
authors.initials: M
authors.lastname: Jibladze
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D015377:Cilastatin / Q000494:pharmacology*; D000077728:Cilastatin, Imipenem Drug Combination; D017719:Diabetic Foot / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology / Q000601:surgery*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D015378:Imipenem / Q000494:pharmacology*; D007511:Ischemia / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D014946:Wound Infection / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D015377:Cilastatin; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination