title: Bilateral cavernous sinus thrombosis following community-acquired methicillin-resistant staphylococcus aureus infection: a case report and review of the literature.
abstract: OBJECTIVE
  We describe a case of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infection leading to bilateral cavernous sinus thrombosis (CST) and subsequent left eye blindness in a previously healthy, immunocompetent woman. A secondary objective is to document all published cases of MRSA induced CST.
  
  
  METHODS
  To identify all relevant publications on MRSA-induced CST in adults.
  
  
  RESULTS
  Seven publications were included in this review describing patients age 19 or older. Together, with the case included in this publication, a total of 8 cases of MRSA induced CST have been documented since 2003. Of interest, to our knowledge this is the first reported case of CA-MRSA CST temporally associated with nasal H1N1 vaccination.
  
  
  CONCLUSIONS
  In selecting empiric antibiotic coverage for septic CST, the practitioner should use antibiotics that are active against CA-MRSA to help prevent morbidity and mortality.
authors.affiliation: School of Medicine, University of Mississippi Medical Center, Jackson 39216, USA.
authors.forename: Rebecca S
authors.initials: RS
authors.lastname: Chick
authors.forename: James K
authors.initials: JK
authors.lastname: Glisson
authors.forename: Samuel
authors.initials: S
authors.lastname: Pierce
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D001766:Blindness / Q000209:etiology; D020226:Cavernous Sinus Thrombosis / Q000188:drug therapy / Q000382:microbiology*; D017714:Community-Acquired Infections / Q000150:complications / Q000382:microbiology; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D055624:Methicillin-Resistant Staphylococcus aureus; D008922:Mississippi; D013207:Staphylococcal Skin Infections / Q000150:complications* / Q000382:microbiology
chemical_list: D007252:Influenza Vaccines