title: [Progress in studies on HCV receptor of Tupaia as a potential hepatitis C animal model].
abstract: Hepatitis C virus is a prevalent and globally distributed human pathogen that seriously harmful to public health. However, the development of therapy and vaccine was impeded by the lack of suit small animal models. Herein, we introduce the characters of HCV replication. Taken the HCV cellular receptors as the viewpoint, the potentiality of tupaia as hepatitis C animal model is discussed at the molecular level by comparing of present animal model.
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming Yunnan 650224, China. liyao420420@163.com
authors.forename: Yao
authors.initials: Y
authors.lastname: Li
authors.forename: Jie-Jie
authors.initials: JJ
authors.lastname: Dai
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Sun
authors.forename: Xue-Shan
authors.initials: XS
authors.lastname: Xia
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D016174:Hepacivirus / Q000235:genetics / Q000502:physiology; D006526:Hepatitis C / Q000235:genetics / Q000378:metabolism* / Q000821:virology; D006801:Humans; D011991:Receptors, Virus / Q000235:genetics / Q000378:metabolism*; D014417:Tupaia / Q000235:genetics / Q000378:metabolism / Q000821:virology
chemical_list: D011991:Receptors, Virus