title: [Development of gene therapy in major brain diseases].
abstract: In recent years, the development of molecular biology and medicine has prompted the research of gene therapy for brain diseases. In this review, we summarized the current gene therapy approaches of major brain diseases. Against the pathogenesis of major brain diseases, including brain tumors, Parkinson's disease, Alzheimer's disease and cerebrovascular disorders, there are several effective gene therapy strategies. It is no doubt that, gene therapy, as a novel treatment, is of great significance for understanding the causes, as well as comprehensive treatment for brain diseases.
authors.affiliation: School of Pharmacy, Fudan University, Shanghai 200032, China.
authors.forename: Li
authors.initials: L
authors.lastname: Fan
authors.forename: Xin-guo
authors.initials: XG
authors.lastname: Jiang
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics / Q000628:therapy*; D001932:Brain Neoplasms / Q000235:genetics / Q000628:therapy*; D002561:Cerebrovascular Disorders / Q000235:genetics / Q000628:therapy*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D010300:Parkinson Disease / Q000235:genetics / Q000628:therapy*