title: Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography.
abstract: To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson's correlation coefficient (r) and Bland-Altman analysis. LV volumes (EDV(-5%) 87.5 ± 17.1 ml, EDV(-10%) 87.7 ± 16.3 ml; ESV(-5%) 32.4 ± 10.6 ml, ESV(-10%) 31.9 ± 9.9 ml; SV(-5%) 55.1 ± 10.5 ml, SV(-10%) 55.8 ± 9.9 ml; mean ± SD) and EF (EF(-5%) 63.4 ± 6.2%, EF(-10%) 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation (r = 0.786-0.896, all P < 0.001) with the 2D-TTE results. The mean required time for CT data analysis in the 20- and 10 phase reconstructions were 15.5 ± 4.0 and 7.3 ± 2.5 min. Within MDCT, using 10-phase image reconstruction is sufficient to evaluate LV volumes and EF, and is also more time-effective than 20-phase reconstruction.
authors.affiliation: Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, 33 Munhwa-ro, Jung-gu, Daejeon 301-721, Korea.
authors.forename: Yeon-jee
authors.initials: YJ
authors.lastname: Ko
authors.forename: Song Soo
authors.initials: SS
authors.lastname: Kim
authors.forename: Woon-Ju
authors.initials: WJ
authors.lastname: Park
authors.forename: Jin-Ok
authors.initials: JO
authors.lastname: Jeong
authors.forename: Sung Min
authors.initials: SM
authors.lastname: Ko
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000592:standards; D011237:Predictive Value of Tests; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000592:standards; D012015:Reference Standards; D056910:Republic of Korea; D012189:Retrospective Studies; D013318:Stroke Volume; D013997:Time Factors; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D016277:Ventricular Function, Left