title: A multiscale theoretical investigation of electric measurements in living bone : piezoelectricity and electrokinetics.
abstract: This paper presents a theoretical investigation of the multiphysical phenomena that govern cortical bone behaviour. Taking into account the piezoelectricity of the collagen-apatite matrix and the electrokinetics governing the interstitial fluid movement, we adopt a multiscale approach to derive a coupled poroelastic model of cortical tissue. Following how the phenomena propagate from the microscale to the tissue scale, we are able to determine the nature of macroscopically observed electric phenomena in bone.
authors.affiliation: Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS (Biomeca), Créteil, France. thibault.lemaire@univ-paris-est.fr
authors.forename: T
authors.initials: T
authors.lastname: Lemaire
authors.forename: E
authors.initials: E
authors.lastname: Capiez-Lernout
authors.forename: J
authors.initials: J
authors.lastname: Kaiser
authors.forename: S
authors.initials: S
authors.lastname: Naili
authors.forename: E
authors.initials: E
authors.lastname: Rohan
authors.forename: V
authors.initials: V
authors.lastname: Sansalone
mesh_terms: D000818:Animals; D001031:Apatites / Q000378:metabolism; D001696:Biomechanical Phenomena; D001857:Bone Matrix / Q000502:physiology; D001842:Bone and Bones / Q000502:physiology*; D003094:Collagen / Q000378:metabolism; D004548:Elasticity; D055724:Electrophysiological Phenomena; D017136:Ion Transport; D055641:Mathematical Concepts; D008954:Models, Biological; D016062:Porosity
chemical_list: D001031:Apatites; D003094:Collagen