title: Concordance between clinical and histopathologic diagnosis in recipient corneas.
abstract: OBJECTIVE
  To specify a concordance rate between the preoperative clinical and the postoperative histopathologic diagnosis in recipient corneas referred to the pathology department of Central Eye Bank of Iran.
  
  
  METHODS
  Concordance and discrepancy between the preoperative clinical and postoperative histopathologic diagnosis of recipient corneal buttons were evaluated.
  
  
  RESULTS
  Overall, 340 corneal specimens were evaluated. The total concordance rate between the clinical and histopathologic diagnoses was 97.5%. The concordance rate in keratoconus, nonspecific scar and opacity, mustard gas keratopathy, combined keratoconus and dystrophy, postkeratorefractive keratectasia, and chemical burns was 100%. Discordant cases were observed in acquired corneal endothelial decompensation, corneal dystrophies, infectious keratitis, and miscellaneous causes, with the rate of 6.0%, 4.1%, 2.8%, and 16.6%, respectively.
  
  
  CONCLUSIONS
  Our series demonstrated a significantly high concordance between the preoperative clinical and the postoperative histopathologic diagnosis in recipient corneas with different types of corneal disorders.
authors.affiliation: Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mrezaie47@yahoo.com
authors.forename: Mozhgan
authors.initials: M
authors.lastname: Rezaei Kanavi
authors.forename: Atefeh
authors.initials: A
authors.lastname: Javadi
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Javadi
authors.forename: Mehdi
authors.initials: M
authors.lastname: Yaseri
authors.forename: Sepehr
authors.initials: S
authors.lastname: Feizi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000175:diagnosis* / Q000601:surgery; D003941:Diagnostic Techniques, Ophthalmological / Q000592:standards*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011237:Predictive Value of Tests; D057234:Preoperative Period; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity