title: Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine.
abstract: Bilayer lipid membranes composed of phosphatidylcholine and decanoic acid or phosphatidylcholine and decylamine were investigated using electrochemical impedance spectroscopy. Interaction between membrane components causes significant deviations from the additivity rule. Area, capacitance, and stability constant values for the complexes were calculated based on the model assuming 1:1 stoichiometry, and the model was validated by comparison of these values to experimental results. We established that phosphatidylcholine and decylamine form highly stable 1:1 complexes. In the case of decanoic acid-modified phosphatidylcholine membranes, complexes with stoichiometries other than 1:1 should be taken into consideration.
authors.affiliation: Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443 Bialystok, Poland. monikan@uwb.edu.pl
authors.forename: Monika
authors.initials: M
authors.lastname: Naumowicz
authors.forename: Aneta Dorota
authors.initials: AD
authors.lastname: Petelska
authors.forename: Zbigniew Artur
authors.initials: ZA
authors.lastname: Figaszewski
mesh_terms: D000465:Algorithms; D000588:Amines / Q000737:chemistry*; D003652:Decanoic Acids / Q000737:chemistry*; D058266:Dielectric Spectroscopy / Q000379:methods*; D008051:Lipid Bilayers / Q000737:chemistry*; D008958:Models, Molecular; D010713:Phosphatidylcholines / Q000737:chemistry*
chemical_list: D000588:Amines; D003652:Decanoic Acids; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; C031071:decanoic acid; C004744:decylamine