title: Pan-resistant Acinetobacter baumannii mediastinitis treated successfully with tigecycline: a case report.
abstract: BACKGROUND
  Mediastinitis due to Acinetobacter baumannii is rare.
  
  
  METHODS
  We report a case of mediastinitis caused by pan-resistant A. baumannii in a patient with multiple comorbidities who underwent cardiopulmonary bypass and we also present a literature review.
  
  
  RESULTS
  Successful treatment consisted of surgical debridement plus drainage, and tigecycline administration for three weeks.
  
  
  CONCLUSIONS
  Surgical source control along with effective antibiotics is essential in the treatment of mediastinitis. Tigecycline has the potential to be an option for pan-resistant A. baumannii mediastinitis.
authors.affiliation: Division of Infectious Diseases and Clinical Microbiology, Türkiye Yüksek Ihtisas Education and Research Hospital, Ankara, Turkey.
authors.forename: Ayşe Yasemin Tezer
authors.initials: AY
authors.lastname: Tekçe
authors.forename: Ayşe
authors.initials: A
authors.lastname: Erbay
authors.forename: Hatice
authors.initials: H
authors.lastname: Çabadak
authors.forename: Serap
authors.initials: S
authors.lastname: Yağcı
authors.forename: Nihal
authors.initials: N
authors.lastname: Karabiber
authors.forename: Süha
authors.initials: S
authors.lastname: Şen
mesh_terms: D000151:Acinetobacter Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D003646:Debridement; D004322:Drainage; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D008480:Mediastinitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage / Q000031:analogs & derivatives*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D000078304:Tigecycline; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline