title: The influence of autonomic interventions on the sleep-wake-related changes in gastric myoelectrical activity in rats.
abstract: BACKGROUND
  Significant changes in autonomic activity occur at sleep-wake transitions and constitute an ideal setting for investigating the modulatory role of the autonomic nervous system on gastric myoelectrical activity (GMA).
  
  
  METHODS
  Using continuous power spectral analysis of electroencephalogram, electromyogram, and electrogastromyogram (EGMG) data from freely moving rats that had undergone chemical sympathetomy and/or truncal vagotomy, sleep-wake-related fluctuations in GMA were compared among the intervention groups.
  
  
  RESULTS
  The pattern and extent of fluctuations in EGMG power across the sleep-wake states was blunted most significantly in rats undergoing both chemical sympathectomy and truncal vagotomy. The effect of these interventions also varied with respect to the transition between different sleep-wake states. The most prominent influences were observed between active waking and quiet sleep and between paradoxical sleep and quiet sleep.
  
  
  CONCLUSIONS
  The sleep-wake-related fluctuations in EGMG power are a result of joint contributions from both sympathetic and vagal innervation. Vagotomy mainly resulted in a reduction in EGMG power, while the role of sympathetic innervation was unveiled by vagotomy and this was reflected most obviously in the extent of the fluctuations in EGMG power.
authors.affiliation: Department of Surgery, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
authors.forename: Y M
authors.initials: YM
authors.lastname: Huang
authors.forename: C C H
authors.initials: CC
authors.lastname: Yang
authors.forename: C J
authors.initials: CJ
authors.lastname: Lai
authors.forename: T B J
authors.initials: TB
authors.lastname: Kuo
mesh_terms: D018663:Adrenergic Agents / Q000378:metabolism; D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D004576:Electromyography / Q000379:methods; D008297:Male; D009130:Muscle, Smooth / Q000502:physiology*; D016627:Oxidopamine / Q000378:metabolism; D051381:Rats; D011921:Rats, Inbred WKY; D012890:Sleep / Q000502:physiology*; D013270:Stomach / Q000294:innervation* / Q000502:physiology*; D014630:Vagus Nerve / Q000502:physiology / Q000601:surgery; D014851:Wakefulness / Q000502:physiology*
chemical_list: D018663:Adrenergic Agents; D016627:Oxidopamine