title: Sleep dysfunctions influence decision making in undemented Parkinson's disease patients: a study in a virtual supermarket.
abstract: In the early-middle stages of Parkinson's disease (PD), polysomnographic studies show early alterations of the structure of the sleep, which may explain frequent symptoms reported by patients, such as daytime drowsiness, loss of attention and concentration, feeling of tiredness. The aim of this study was to verify if there is a correlation between the sleep dysfunction and decision making ability. We used a Virtual Reality version of the Multiple Errand Test (VMET), developed using the NeuroVR free software (http://www.neurovr2.org), to evaluate decision-making ability in 12 PD not-demented patients and 14 controls. Five of our not-demented 12 PD patients showed abnormalities in the polysomnographic recordings associated to significant differences in the VMET performance.
authors.affiliation: Department of Neurosciences and Neurorehabilitation, Istituto Auxologico Italiano, IRCCS, Piancavallo-Verbania, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Albani
authors.forename: Simona
authors.initials: S
authors.lastname: Raspelli
authors.forename: Laura
authors.initials: L
authors.lastname: Carelli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Priano
authors.forename: Riccardo
authors.initials: R
authors.lastname: Pignatti
authors.forename: Francesca
authors.initials: F
authors.lastname: Morganti
authors.forename: Andrea
authors.initials: A
authors.lastname: Gaggioli
authors.forename: Patrice L
authors.initials: PL
authors.lastname: Weiss
authors.forename: Rachel
authors.initials: R
authors.lastname: Kizony
authors.forename: Noomi
authors.initials: N
authors.lastname: Katz
authors.forename: Alessandro
authors.initials: A
authors.lastname: Mauro
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Riva
mesh_terms: D003657:Decision Making; D003704:Dementia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D017286:Polysomnography / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012893:Sleep Wake Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D014584:User-Computer Interface