title: Silyl-substituted 1,3-butadienes for Diels-Alder reaction, ene reaction and allylation reaction.
abstract: Silyl-substituted 1,3-butadienes are useful building blocks and are readily applied in several types of reactions such as Diels-Alder reaction, ene reaction and allylation. They can also participate in different tandem reactions such as Diels-Alder/allylation, ene/allylation, ene/allylation/Diels-Alder reaction, ene/allylation/ene reaction and ene/allylation/Diels-Alder/allylation reaction. This feature article reviews the synthesis of silyl-substituted 1,3-butadienes, and their applications in the reaction types mentioned above, involving a tandem Diels-Alder/ene/allylation process. This article also introduces some reactions of alkenylsilanes and allylsilanes for comparison and discussion about the tandem reaction. The tandem reactions described in this article are a powerful tool to construct complicated multicyclic compounds with high selectivity and high efficiency.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing, China 100871.
authors.forename: Fei
authors.initials: F
authors.lastname: Zhao
authors.forename: Shaoguang
authors.initials: S
authors.lastname: Zhang
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Xi
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
chemical_list: D000475:Alkenes; D002070:Butadienes; D012821:Silanes; C031763:1,3-butadiene