title: Counseling and outcomes of antenatally diagnosed congenital heart anomalies in Turkey.
abstract: OBJECTIVE
  To determine the clinical outcomes and decisions of families of fetuses with prenatally-diagnosed cardiac abnormalities.
  
  
  METHODS
  Prenatally diagnosed cases (n=155) with congenital heart disease were retrospectively categorized according to the Allan-Huggon grading system: Group A (cardiac disease associated with severe / lethal extracardiac disease); Group B1 (low risk with a postnatal prognosis); Group B2 (moderate risk, amenable to surgical repair with a low mortality); and Group B3 (high risk, associated with high mortality after surgery). Neonatal outcomes, including termination of pregnancy, were recorded for 18 months of follow-up after counseling the parents. Student's t-test, Mann-Whitney U, Pearson's Chi-square test and Fischer's exact Chi-square test were used for statistical analyses.
  
  
  RESULTS
  One hundred forty-five cases completed follow up. Thirty-nine cases (Group A) were associated with extracardiac lethal defects and the pregnancies were terminated; these cases were excluded from statistical evaluation. Twenty parents in Group B3 opted also for termination. The survival rates of ongoing pregnancies after 18 months of follow-up between the three cardiac abnormality Groups (Group B1, n=37; Group B2, n=12; and Group B3, n=37) were 89.2%, 66.7%, and 13.5%, respectively. Significance was present between the survival rates of the three Groups [Group B3 vs. Group B1: p=0.0001; OR: 52.8 (12.9-214.5); Group B3 vs. Group B2: p=0.0009; OR: 12.8 (2.8-58.9); Group B2 vs. Group B1: p=0.087; OR: 4.12 (0.84-20.2)].
  
  
  CONCLUSIONS
  Our practice and the findings reported herein support the efficacy of this staging system and counseling parents of fetuses for congenital heart diseases.
authors.affiliation: Clinic of Obstetrics and Gynecology, İstanbul Bakırköy Maternity and Children Diseases Hospital, İstanbul, Turkey. alged_1971@yahoo.com
authors.forename: Ali
authors.initials: A
authors.lastname: Gedikbaşı
authors.forename: Kazım
authors.initials: K
authors.lastname: Oztarhan
authors.forename: Gökhan
authors.initials: G
authors.lastname: Yıldırım
authors.forename: Ahmet
authors.initials: A
authors.lastname: Gül
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Ceylan
mesh_terms: D000029:Abortion, Legal / Q000706:statistics & numerical data; D000293:Adolescent; D000328:Adult; D003376:Counseling; D004452:Echocardiography; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000523:psychology* / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D011379:Prognosis; D012189:Retrospective Studies; D014421:Turkey; D016216:Ultrasonography, Prenatal; D055815:Young Adult