title: More on: endoplasmic reticulum loop VKORC1 substitutions cause warfarin resistance but do not diminish gamma-carboxylation of the vitamin K-dependent coagulation factors.
authors.forename: D J
authors.initials: DJ
authors.lastname: Harrington
authors.forename: S
authors.initials: S
authors.lastname: Siddiq
authors.forename: S L
authors.initials: SL
authors.lastname: Allford
authors.forename: M J
authors.initials: MJ
authors.lastname: Shearer
authors.forename: A D
authors.initials: AD
authors.lastname: Mumford
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000494:pharmacology; D001281:Atrial Fibrillation / Q000097:blood / Q000628:therapy; D019735:Carbon-Carbon Ligases / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D006899:Mixed Function Oxygenases / Q000235:genetics*; D010641:Phenotype; D014807:Vitamin D / Q000378:metabolism; D064417:Vitamin K Epoxide Reductases; D014859:Warfarin / Q000494:pharmacology*
chemical_list: D000925:Anticoagulants; D014807:Vitamin D; D014859:Warfarin; D006899:Mixed Function Oxygenases; C578523:VKORC1 protein, human; D064417:Vitamin K Epoxide Reductases; D019735:Carbon-Carbon Ligases; C020660:glutamyl carboxylase