title: RNA localization in bacteria.
abstract: Bacteria localize proteins and DNA regions to specific subcellular sites, and several recent publications show that RNAs are localized within the cell as well. Localization of tmRNA and some mRNAs indicates that RNAs can be sequestered at specific sites by RNA binding proteins, or can be trapped at the location where they are transcribed. Although the functions of RNA localization are not yet completely understood, it appears that one function of RNA localization is to regulate RNA abundance by controlling access to nucleases. New techniques for visualizing RNAs will likely lead to increased examination of spatial control of RNAs and the role this control plays in the regulation of gene expression and bacterial physiology.
authors.affiliation: Department of Biochemistry and Molecular Biology, Penn State University, 401 Althouse Laboratory, University Park, PA 16802, USA.kkeiler@psu.edu
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Keiler
mesh_terms: D001419:Bacteria / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D011485:Protein Binding; D020871:RNA Stability; D012329:RNA, Bacterial / Q000032:analysis / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000032:analysis / Q000378:metabolism
chemical_list: D012329:RNA, Bacterial; D016601:RNA-Binding Proteins