title: [Macrostructure of sleep in patients with vascular cognitive impairment-no dementia].
abstract: OBJECTIVE
  To investigate the sleep structure in patients with vascular cognitive impairment-no dementia (VCI-ND) and its differences from that of normal individuals.
  
  
  METHODS
  The whole night sleep record of 20 patients with VCI-ND were monitored by 32-head video-taped polysomnographic system, and the results were compared with the data of 20 normal subjects.
  
  
  RESULTS
  Compared with normal subjects, patients with VCI-ND showed significantly reduced total sleep duration, increased waking times, increased stage 1 sleep, decreased stage 2 sleep, decreased stage 3 sleep, decreased rapid eye movement stage (REM) and reduced sleep efficiency.
  
  
  CONCLUSIONS
  Increased light sleep as well as decreased slow-wave stage 3-4 sleep and decreased REM stage may be a specific electroneurophysiologic marker for VCI-ND, but large-sampled multi-centered randomized controlled trial is necessary to test the validity of these features as specific markers for screening and early diagnostic purposes.
authors.affiliation: Department of Neurology, Second Affiliated Hospital of Nanchang University, Nanchang 330006, China. helenju@163.com
authors.forename: Mu-feng
authors.initials: MF
authors.lastname: Zhu
authors.forename: Li-ying
authors.initials: LY
authors.lastname: Deng
authors.forename: Li-min
authors.initials: LM
authors.lastname: Gong
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.forename: Yong-min
authors.initials: YM
authors.lastname: Ding
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D015140:Dementia, Vascular / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages; D012893:Sleep Wake Disorders / Q000209:etiology*; D020521:Stroke / Q000150:complications*