title: [Studies on the changes of chemical constituent in Inula nervosa during the processing].
abstract: OBJECTIVE
  To research the changes of chemical constituent in Inula nervosa during the processing.
  
  
  METHODS
  Inula nervosa processed with different conditions was determined by HPLC,with acetonitrile--water as a mobile phase using gradient elution, and the detective wavelength was 280 nm. The emerging compounds 1 was extracted by 50% ethanol, isolated and purified using chromatography, and identified according to the physicochemical properties and spectral analysis.
  
  
  RESULTS
  The HPLC chromatogram of lnula nervosa changes before and after processing. A monomer compounds was isolated from processed Inula nervosa. It was Identified as 5-hydroxymethylfurfural.
  
  
  CONCLUSIONS
  The chemical constituent of Inula nervosa changes during the processing. It is the first time that compound 1 were isolated from Inula.
authors.affiliation: Kunming Institute of Pattra Medicine, Kunming 650217, China.
authors.forename: Shu-Juan
authors.initials: SJ
authors.lastname: Yang
authors.forename: Zeng-Ming
authors.initials: ZM
authors.lastname: Yang
authors.forename: Hai-Yu
authors.initials: HY
authors.lastname: Zhou
authors.forename: Yue-Ping
authors.initials: YP
authors.lastname: Tan
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000032:analysis / Q000302:isolation & purification; D038143:Inula / Q000737:chemistry*; D009822:Oils, Volatile / Q000032:analysis / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods; D013696:Temperature; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D012997:Solvents; C008046:5-hydroxymethylfurfural; D005662:Furaldehyde