title: Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks.
abstract: An exploration of imidazolylpropargyl amides as linchpin synthons for the construction of a diverse array of heterocyclic frameworks, many of which are related to those found in the oroidin derived alkaloids, is described. One such intermediate has been used in a formal total synthesis of cyclooroidin.
authors.affiliation: Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas 76019, United States.
authors.forename: Manojkumar R
authors.initials: MR
authors.lastname: Bhandari
authors.forename: Muhammed
authors.initials: M
authors.lastname: Yousufuddin
authors.forename: Carl J
authors.initials: CJ
authors.lastname: Lovely
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000577:Amides; D000818:Animals; D003500:Cyclization; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000470:Alkaloids; D000577:Amides; D011758:Pyrroles; C558414:cyclooroidin; C077209:oroidin