title: Bronchoalveolar lavage fluid of lung cancer patients: mapping the uncharted waters using proteomics technology.
abstract: The search for proteome-level markers of non-small cell lung cancer (NSCLC) has been mainly limited to serum or cell line screening approaches up to this point. We would like to demonstrate by this proof-of-principle study investigating bronchoalveolar lavage fluid samples from a cohort of NSCLC and control patients, that this readily available biofluid might be a more suitable source for discovering clinically usable NSCLC biomarkers.
authors.forename: Tonio
authors.initials: T
authors.lastname: Oumeraci
authors.forename: Bernd
authors.initials: B
authors.lastname: Schmidt
authors.forename: Thomas
authors.initials: T
authors.lastname: Wolf
authors.forename: Marc
authors.initials: M
authors.lastname: Zapatka
authors.forename: Andreas
authors.initials: A
authors.lastname: Pich
authors.forename: Benedikt
authors.initials: B
authors.lastname: Brors
authors.forename: Roland
authors.initials: R
authors.lastname: Eils
authors.forename: Michael
authors.initials: M
authors.lastname: Fleischhacker
authors.forename: Brigitte
authors.initials: B
authors.lastname: Schlegelberger
authors.forename: Nils
authors.initials: N
authors.lastname: von Neuhoff
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001992:Bronchoalveolar Lavage Fluid; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D013058:Mass Spectrometry; D040901:Proteomics
chemical_list: D014408:Biomarkers, Tumor