title: Preparation of chitin butyrate by using phosphoryl mixed anhydride system.
abstract: Acylation of chitin with butyric acid was performed in the presence of trifluoroacetic anhydride/phosphoric acid mediated system. The products were characterized by (1)H NMR and FT-IR spectroscopy and their solubility was tested in different organic solvents. Inclusion of butyric acid moieties into the parent molecule was confirmed from the (1)H NMR and FT-IR spectra. FT-IR analysis revealed that the degree of acid substitution (DS) of the products was in a range of 1.9-2.38, which increased with increasing the amounts of butyric acid added to the reaction system. Degree of N-deacetylation (DD) of the products, as determined by (1)H NMR was between 54.2% and 65.6%. The products with DS >2.0 were soluble in dimethyl sulfoxide, N,N-dimethylformamide, tetrahydrofuran, methanol, acetone, chloroform, and acetic acid.
authors.affiliation: Department of Bionanochemistry, School of Natural Sciences, Wonkwang University, Iksan, Chonbuk 570-749, Republic of Korea.
authors.forename: Lok Ranjan
authors.initials: LR
authors.lastname: Bhatt
authors.forename: Bo Mi
authors.initials: BM
authors.lastname: Kim
authors.forename: Kim
authors.initials: K
authors.lastname: Hyun
authors.forename: Kyung Hee
authors.initials: KH
authors.lastname: Kang
authors.forename: Chichong
authors.initials: C
authors.lastname: Lu
authors.forename: Kyu Yun
authors.initials: KY
authors.lastname: Chai
mesh_terms: D000089:Acetic Anhydrides; D000215:Acylation; D000812:Anhydrides / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry*; D002686:Chitin / Q000737:chemistry*; D005463:Fluoroacetates; D009682:Magnetic Resonance Spectroscopy; D010756:Phosphoric Acids / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014269:Trifluoroacetic Acid / Q000737:chemistry
chemical_list: D000089:Acetic Anhydrides; D000812:Anhydrides; D002087:Butyrates; D005463:Fluoroacetates; D010756:Phosphoric Acids; D002686:Chitin; C017958:trifluoroacetic anhydride; C030242:phosphoric acid; D014269:Trifluoroacetic Acid