title: Innate immunity to intracellular pathogens: macrophage receptors and responses to microbial entry.
abstract: Innate immunity to intracellular pathogens encompasses a range of interactions of cellular and humoral activities of the host with the invading microorganism, determining the outcome of infection. Here, we review the particular role of macrophage recognition receptors and effector responses in the uptake of microbes and their products. We place this in context and raise issues for discussion and further experimentation.
authors.affiliation: Department of Primary Health Care, University of Oxford, Oxford, UK.
authors.forename: Annette
authors.initials: A
authors.lastname: Plüddemann
authors.forename: Subhankar
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: Siamon
authors.initials: S
authors.lastname: Gordon
mesh_terms: D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate; D008264:Macrophages / Q000276:immunology* / Q000382:microbiology; D051192:Receptors, Pattern Recognition
chemical_list: D051192:Receptors, Pattern Recognition