title: In vitro activity of telavancin and comparator antimicrobial agents against a panel of genetically defined staphylococci.
abstract: The in vitro activity of telavancin was determined for 94 diverse Staphylococcus spp. Telavancin had MIC(90) values of 0.5 μg/mL for methicillin-susceptible, methicillin-resistant, and vancomycin-susceptible Staphylococcus aureus, and coagulase-negative staphylococci isolates. Telavancin MICs were 0.5-1 μg/mL for vancomycin-intermediate S. aureus isolates and 2-4 μg/mL for vancomycin-resistant S. aureus strains.
authors.affiliation: Quotient BioResearch, UK. david-farrell@jmilabs.com
authors.forename: David J
authors.initials: DJ
authors.lastname: Farrell
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Krause
authors.forename: Bret M
authors.initials: BM
authors.lastname: Benton
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003030:Coagulase; D018432:Drug Resistance, Multiple; D000077427:Lipoglycopeptides; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics; D020713:Vancomycin Resistance
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D003030:Coagulase; D000077427:Lipoglycopeptides; C487637:telavancin