title: [Intra-operative histochemical detection of vitalized muscular tissue during lower limb amputation for chronic critical ischemia].
abstract: Direct results of 747 lower limb amputations for chronic critical lower limb ischemia were analyzed. Early postoperative complications were observed in 45,1% of cases. Among them 45,4% were caused by tissue ischemia. Basing on detection of lactate dehydrogenase activity in muscular tissue method of intra-operative evaluation of tissue ischemia at the level of amputation is proposed. Relationship between this index and frequency of early postoperative complications is proved.
authors.forename: V O
authors.initials: VO
authors.lastname: Tsvetkov
authors.forename: V V
authors.initials: VV
authors.lastname: Kochubeĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Filippov
mesh_terms: D000368:Aged; D000671:Amputation, Surgical / Q000009:adverse effects / Q000145:classification / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000150:complications* / Q000503:physiopathology; D001158:Arteries / Q000503:physiopathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D045022:Lactate Dehydrogenases / Q000378:metabolism; D035002:Lower Extremity / Q000098:blood supply / Q000601:surgery; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D018482:Muscle, Skeletal / Q000378:metabolism*; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications / Q000517:prevention & control*; D012039:Regional Blood Flow; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D045022:Lactate Dehydrogenases