title: Randomized controlled multicentre trial of cognitive behaviour therapy in the early initial prodromal state: effects on social adjustment post treatment.
abstract: OBJECTIVE
  Improvement of social adjustment is a major aim of indicated prevention in young people at risk of developing psychosis. The present study explores the effect of specific cognitive behaviour therapy (CBT) as compared with supportive counselling (SC) on social adjustment in people in a potential early initial prodromal state of psychosis (EIPS) primarily defined by self-experienced cognitive thought and perception deficits (basic symptoms).
  
  
  METHODS
  A total of 128 help-seeking outpatients in the EIPS were randomized to receive either specific CBT or SC for 12 months. Social adjustment was assessed with the Social Adjustment Scale II (SAS II) at baseline, time of transition or post treatment
  
  
  RESULTS
  From 113 patients, who completed the SAS II at intake, 67 (59.3%) completed the SAS assessments at time of transition or post treatment. Both specific CBT and SC resulted in improvements in scales of SAS II, with no significant between-group differences post treatment.
  
  
  CONCLUSIONS
  Although treatment in specially designed early detection and intervention centres improves functioning of people in the EIPS, specific CBT was not superior to SC. One could hypothesize that additional vocational rehabilitation, case management and involvement of multidisciplinary teams are needed to further improve short-term outcome of specific interventions on this dimension.
authors.affiliation: Department of Psychiatry and Psychotherapy, University of Cologne, Cologne,Germany. andreas.bechdolf@uk-koeln.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Bechdolf
authors.forename: Michael
authors.initials: M
authors.lastname: Wagner
authors.forename: Verena
authors.initials: V
authors.lastname: Veith
authors.forename: Stephan
authors.initials: S
authors.lastname: Ruhrmann
authors.forename: Ralf
authors.initials: R
authors.lastname: Pukrop
authors.forename: Anke
authors.initials: A
authors.lastname: Brockhaus-Dumke
authors.forename: Julia
authors.initials: J
authors.lastname: Berning
authors.forename: Elmar
authors.initials: E
authors.lastname: Stamm
authors.forename: Birgit
authors.initials: B
authors.lastname: Janssen
authors.forename: Petra
authors.initials: P
authors.lastname: Decker
authors.forename: Ronald
authors.initials: R
authors.lastname: Bottlender
authors.forename: Hans-Jurgen
authors.initials: HJ
authors.lastname: Moller
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Gaebel
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Maier
authors.forename: Joachim
authors.initials: J
authors.lastname: Klosterkotter
mesh_terms: D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003376:Counseling / Q000379:methods; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D010349:Patient Compliance; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000628:therapy*; D012917:Social Adjustment