title: Orbital metastases as the first manifestation of lung adenocarcinoma.
abstract: Reduction in visual acuity due to orbital metastasis is rarely the first sign of lung cancer and very few cases have been published in the literature. Here we report a rare case of lung adenocarcinoma with orbital metastasis as the first presenting sign. The incidence of primary tumors that metastasize to the orbit is approximately 7%. In 19% of the cases, there is no history of cancer when the patient presents with ophthalmic symptoms, and in 10%, the primary site remains obscure despite intensive systemic evaluation. Our patient showed a partial improvement in vision after successful combination of chemotherapy and radiotherapy. Blurred vision due to orbital metastasis as the primary symptom of lung cancer is very uncommon. A great index of suspicion is essential when an orbital lesion appears.
authors.affiliation: Pulmonary Clinic of Aristotle University of Thessaloniki, Greece.
authors.forename: Paul
authors.initials: P
authors.lastname: Zarogoulidis
authors.forename: Eirini
authors.initials: E
authors.lastname: Terzi
authors.forename: Georgios
authors.initials: G
authors.lastname: Kouliatsis
authors.forename: Sofia
authors.initials: S
authors.lastname: Androuli
authors.forename: Theodoros
authors.initials: T
authors.lastname: Kontakiotis
authors.forename: Thomas
authors.initials: T
authors.lastname: Zaramboucas
authors.forename: Kostas
authors.initials: K
authors.lastname: Zarogoulidis