title: Application of Mitsunobu reagents to redox isomerization of CF3-containing propargylic alcohols to (E)-α,β-enones.
abstract: Isomerization of CF(3)-containing secondary propargylic alcohols proceeds with excellent E selectivity by treatment with Mitsunobu reagents, tris(p-methoxyphenyl)phosphine (TMPP), and 1,1'-(azodicarbonyl)dipiperidine (ADDP) in the presence of phenol.
authors.affiliation: Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakacho, Koganei 184-8588, Japan.
authors.forename: Yohsuke
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamazaki
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D007536:Isomerism; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D020005:Propanols / Q000737:chemistry*; D028561:Transition Elements / Q000737:chemistry
chemical_list: D000475:Alkenes; D000480:Alkynes; D007202:Indicators and Reagents; D007659:Ketones; D020005:Propanols; D028561:Transition Elements; D005461:Fluorine; C028255:propargyl alcohol