title: Extremely high serum ferritin levels as a main diagnostic tool of adult-onset Still's disease.
abstract: Adult-onset Still's disease is a rare systemic inflammatory disease of unknown aetiology characterised by typical symptoms including daily high spiking fever, evanescent salmon-pink rash, sore throat, arthritis/arthralgias and polyserositis. The laboratory findings usually show neutrophilic leucocytosis, seronegativity and raised serum transaminases. We describe six typical cases. All of them had serum ferritin above 5,000 µg/L. Although there are few theories about the origin of the high ferritin level, an extremely high serum ferritin above 5,000 µg/L should be the main diagnostic tool of adult-onset Still's disease.
authors.affiliation: Rheumatology and Clinical Immunology Department, Internal Medicine, University Hospital (CHC) Rijeka, Rijeka, Croatia. srdan.novak@ri.htnet.hr
authors.forename: Srdan
authors.initials: S
authors.lastname: Novak
authors.forename: Felina
authors.initials: F
authors.lastname: Anic
authors.forename: Tea Schnurrerer
authors.initials: TS
authors.lastname: Luke-Vrbanić
mesh_terms: D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000097:blood / Q000175:diagnosis; D003937:Diagnosis, Differential; D005076:Exanthema / Q000097:blood / Q000175:diagnosis; D005260:Female; D005293:Ferritins / Q000097:blood*; D005334:Fever / Q000097:blood / Q000175:diagnosis; D006801:Humans; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000097:blood / Q000175:diagnosis*
chemical_list: D005293:Ferritins