title: Shortcuts to making cardiomyocytes.
abstract: The adult human heart lacks sufficient regenerative capacity to recover after a myocardial infarction. Cell-based therapy has emerged as a potential treatment for the failing heart; however, a key issue for the success of future cell-based therapies is the ability to obtain patient-specific high-quality cardiomyocytes in a fast and efficient manner. Recent progress has been made towards this goal using reprogramming-based approaches.
authors.forename: Huansheng
authors.initials: H
authors.lastname: Xu
authors.forename: B Alexander
authors.initials: BA
authors.lastname: Yi
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Chien
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D006331:Heart Diseases / Q000473:pathology; D006801:Humans; D008954:Models, Biological; D009203:Myocardial Infarction / Q000628:therapy*; D032383:Myocytes, Cardiac / Q000166:cytology*; D010766:Phosphorylation; D044968:Regenerative Medicine; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology; D013312:Stress, Physiological