title: [An update on systemic sclerosis].
abstract: Systemic sclerosis affects multiple internal organs and systems and is characterized by high clinical variability. Early diagnosis of the disease itself and of organ involvement plays a key role in the management of systemic sclerosis. The prognosis for each patient is equally important. In recent years there has been significant progress in our understanding of the pathogenesis and clinical course of the disease as well as in new therapeutic strategies for scleroderma-associated organ complications. The aim of this review is to present recent advances in the diagnosis, prognosis, and treatment of systemic sclerosis.
authors.affiliation: Klinika Reumatologii i Chorób Wewnetrznych Uniwersytetu Medycznego w Białymstoku ul. M. Skłodowskiej-Curie 24A, 15-276 Białystok.
authors.forename: Otylia
authors.initials: O
authors.lastname: Kowal-Bielecka
mesh_terms: D002423:Cause of Death; D018450:Disease Progression; D042241:Early Diagnosis; D006801:Humans; D017410:Practice Guidelines as Topic; D011379:Prognosis; D019984:Quality Indicators, Health Care; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000628:therapy*