title: Selective oxidation of steroidal allylic alcohols using pyrazole and pyridinium chlorochoromate.
abstract: ABASTRACT: This paper presents a modified method for the selective oxidation of allylic alchols. Pyrazole, when used with pyridinium chlorochromate, is a mild and useful reagent system for the rapid and selective oxidation of steroidal allylic alcohols to the corresponding α, β-unsaturated ketones. The reaction of each substrate was carried out by adding the oxidant to a dry methylene chloride solution containing pyrazole and an allylic alchol. This report is the first on the use of pyrazole to augment selective oxidation by a chronium (VI) reagent.
authors.affiliation: Department of Chemistry, Auburn University, 36849, Auburn, AL.
authors.forename: E J
authors.initials: EJ
authors.lastname: Parish
authors.forename: S
authors.initials: S
authors.lastname: Chitrakorn
authors.forename: S
authors.initials: S
authors.lastname: Lowery