title: Laparoscopic sleeve gastrectomy with duodenojejunal bypass for the treatment of type 2 diabetes in non-obese patients: technique and preliminary results.
abstract: BACKGROUND
  Medical treatment of type 2 diabetes has often insufficient clinical results at long term. Although the surgical option is a well-established alternative for obese patients, the procedures in non-obese are currently being developed.
  
  
  METHODS
  A 12-month prospective trial with ten diabetic non-obese patients who underwent laparoscopic sleeve gastrectomy with duodenojejunal bypass is presented. Changes in fasting blood glucose, HbA1c, weight, and BMI were determined.
  
  
  RESULTS
  There was a significant reduction in fasting glycemia and HbA1c at 1 year postoperative (p < 0.004). One patient had an intra-abdominal bleeding and a wound infection treated with blood transfusion and antibiotic therapy, respectively. The BMI decreased 12.1% and in any case it was reduced to less than 20 kg/m².
  
  
  CONCLUSIONS
  Laparoscopic sleeve gastrectomy with duodenojejunal bypass is a promising procedure for the treatment of non-obese patients with type 2 diabetes. Studies with large number of patients and longer follow-up are necessary to make definitive conclusions.
authors.affiliation: Department of Surgery, Faculty of Medicine, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela, navarretesalvador@yahoo.com.
authors.forename: Salvador Antonio
authors.initials: SA
authors.lastname: Navarrete
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Leyba
authors.forename: Salvador Navarrete
authors.initials: SN
authors.lastname: Llopis
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin