title: [Comparative analysis of abnormal Pap smear and the results of histopathological examination of specimens from the cervix of the programme in-depth diagnosis cervical cancer conducted at the of Operational Gynecology Department ICZMP in Lodz].
abstract: BACKGROUND
  Cervical Cancer Screening Program has been operational in Poland for over four years. Colposcopy and guided biopsy methods constitute an essential part of population-based screening, enable stating right diagnosis and planning treatment procedures.
  
  
  OBJECTIVE
  The aim of the following study was to analyse the diagnostic acuity of cyto- and histopathological examination.
  
  
  RESULTS
  We examined 510 patients with the following result of cytological smear: ASCUS--265 women (51.96%), LSIL--167 cases (35.75%), HSIL--78 women (15.29%). Complete agreement between cytological smear and guided biopsy histopathology was observed among 81.13% cases of ASCUS, in 88.02% of women with LSIL and in 76.92% cases with the diagnosis of HSIL. As with cytology-biopsy comparisons, discordant cases were significantly more frequent in the group with stated HSIL than among patients with the diagnosis of ASCUS or LSIL (p<0.001).
  
  
  CONCLUSIONS
  1. High cyto-histopathological accordance (82%) has been obtained, what is comparable with the data in literature. 2. The highest cyto- histopathological compatibility was obtained in the group of patients with LSIL--over 88%, and the lowest in the group of patients with HSIL--less than 77%. 3. Failure to confirm the histopathological diagnosis of cytological HSIL requires further molecular and morphological evaluation.
authors.affiliation: Klinika Ginekologii Operacyjnej Instytut Centrum Zdrowia Matki Polki w Łodzi. kbkulig@wp.pl
authors.forename: Bartosz
authors.initials: B
authors.lastname: Kulig
authors.forename: Stanisław
authors.initials: S
authors.lastname: Łukaszek
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Brucka
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kałuzyński
authors.forename: Anna
authors.initials: A
authors.lastname: Kamer-Bartosińska
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Szyłło
mesh_terms: D000328:Adult; D003127:Colposcopy / Q000706:statistics & numerical data; D055088:Early Detection of Cancer / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000458:organization & administration / Q000706:statistics & numerical data*; D008875:Middle Aged; D010044:Outpatient Clinics, Hospital / Q000458:organization & administration; D065006:Papanicolaou Test; D011044:Poland / Q000453:epidemiology; D002578:Uterine Cervical Dysplasia / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D014626:Vaginal Smears / Q000379:methods / Q000706:statistics & numerical data*; D016387:Women's Health