title: [Effect of Toll-like receptors on helminth infection].
abstract: Toll-like receptors (TLRs) as a family of pattern-recognition receptors are vital for immune and inflammatory responses, and also play an important role in helminth infection. By regulating TLRs expression and function, helminth can alter host immune response, interfere with disease progression, and change the immune microenvironment of host. This review summarizes the biological characteristics of TLRs and recent advances of TLRs in immune modulation on helminth infection.
authors.affiliation: Departmnent of Medical Parasitology, School of Basic Medical Sciences, Peking University, Beljing 100191, China. yuyr@bjmu.edu.cn
authors.forename: Yan-Rong
authors.initials: YR
authors.lastname: Yu
authors.forename: Yong-Fen
authors.initials: YF
authors.lastname: Qi
mesh_terms: D000818:Animals; D006373:Helminthiasis / Q000276:immunology*; D007113:Immunity, Innate; D051193:Toll-Like Receptors / Q000276:immunology*
chemical_list: D051193:Toll-Like Receptors