title: Silica coating improves the efficacy of Pd nanosheets for photothermal therapy of cancer cells using near infrared laser.
abstract: Thickness does matter! The ultrathin nature of 1.8 nm-thick Pd nanosheets prevents them entering cells effectively. A 13-times enhancement in the cells' uptake of the Pd nanosheets has now been achieved by silica coating together with surface functionalization, therefore significantly improving their NIR photothermal cell-killing efficacy.
authors.affiliation: State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Shaoheng
authors.initials: S
authors.lastname: Tang
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Huang
authors.forename: Nanfeng
authors.initials: N
authors.lastname: Zheng
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry / Q000627:therapeutic use*; D009369:Neoplasms / Q000532:radiotherapy*; D010165:Palladium / Q000737:chemistry / Q000627:therapeutic use*; D012822:Silicon Dioxide / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D010165:Palladium; D012822:Silicon Dioxide