title: Impact of endoscopic ultrasonography on the management of a prospective cohort of 700 consecutive patients referred for diagnostic endoscopic ultrasonography.
abstract: BACKGROUND
  endoscopic ultrasonography (EUS) is a high accuracy technique for the study of many digestive diseases. The degree of knowledge about the impact of EUS on the management of these patients is inadequate.
  
  
  OBJECTIVE
  to determine the therapeutic impact of endoscopic ultrasonography (EUS) on a prospective cohort of patients.
  
  
  METHODS
  all patients referred for EUS over a period of 2 years were prospectively evaluated in order to asses: 1. EUS provides new information not previously known; 2. theoretic impact of EUS on patient management; 3. real impact of EUS on final therapy; 4. changes in the aggressiveness of the therapeutic decision after EUS.
  
  
  RESULTS
  700 patients were included. Preoperative assessment of digestive tumors was the commonest indication. EUS provided "new information" in the 89% of the patients. With regard to endoscopist opinion, these findings should alter the management in 79% of patients ("theoretic impact"). However, EUS prompted a change in the management in 67% of patients ("real impact"). Final therapy post-EUS was less aggressive in 34% of patients. Changes in therapeutic decision were associated with EUS findings, alcohol intake and age ≥ 57 years old.
  
  
  CONCLUSIONS
  1) EUS findings, advanced age, and alcohol intake are associated with a change in the management in 2 out of every 3 patients referred for EUS. 2) Therapeutic decision (post-EUS) is less aggressive in a third of these patients, what should represent a significant economic saving.
authors.affiliation: Endoscopy Unit, Digestive Diseases Department, Quirón University Hospital, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: González-Panizo
authors.forename: E
authors.initials: E
authors.lastname: Vázquez-Sequeiros
authors.forename: J R
authors.initials: JR
authors.lastname: Foruny Olcina
authors.forename: V
authors.initials: V
authors.lastname: Defarges Pons
authors.forename: M
authors.initials: M
authors.lastname: García
authors.forename: D
authors.initials: D
authors.lastname: Boixeda de Miquel
authors.forename: V
authors.initials: V
authors.lastname: Moreira Vicente
authors.forename: D
authors.initials: D
authors.lastname: Juzgado Lucas
authors.forename: J M
authors.initials: JM
authors.lastname: Milicua Salamero
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015331:Cohort Studies; D004066:Digestive System Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000628:therapy; D004067:Digestive System Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D019160:Endosonography; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging; D041981:Gastrointestinal Tract / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012959:Socioeconomic Factors; D016896:Treatment Outcome; D055815:Young Adult