title: Determination of boron concentration in blood and tissue samples from patients with liver metastases of colorectal carcinoma using Prompt Gamma Ray Activation Analysis (PGAA).
abstract: As part of the studies on Boron Neutron Capture Therapy at the University of Mainz, Germany, a clinical trial has been started in which, four patients suffering from liver metastases of colorectal carcinoma have been enrolled. Specimens of blood and healthy tissue samples taken from the patients were measured at the PGAA facilities at the HFR in Petten, The Netherlands, and at the FRM II in Munich, Germany. From the measured boron concentrations, pharmacokinetic curves and blood-to-tissue concentration ratios were produced.
authors.affiliation: Institute for Nuclear Chemistry, University of Mainz, Fritz-Strassmann-Weg 2, Mainz, Germany. schmito@uni-mainz.de
authors.forename: T
authors.initials: T
authors.lastname: Schmitz
authors.forename: K
authors.initials: K
authors.lastname: Appelman
authors.forename: P
authors.initials: P
authors.lastname: Kudejova
authors.forename: C
authors.initials: C
authors.lastname: Schütz
authors.forename: J V
authors.initials: JV
authors.lastname: Kratz
authors.forename: R
authors.initials: R
authors.lastname: Moss
authors.forename: G
authors.initials: G
authors.lastname: Otto
authors.forename: G
authors.initials: G
authors.lastname: Hampel
mesh_terms: D001895:Boron / Q000097:blood / Q000378:metabolism*; D015179:Colorectal Neoplasms / Q000097:blood / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000556:secondary* / Q000601:surgery
chemical_list: D001895:Boron