title: Intra-aortic balloon pump use and outcomes with current therapies.
abstract: OBJECTIVE
  Our purpose was to describe the contemporary utilization, clinical outcomes and complication rates of intra-aortic balloon pump (IABP) therapy in this current age.
  
  
  BACKGROUND
  IABP use and outcomes, in the setting of modern antiplatelet therapy and primary percutaneous coronary intervention and the use of drug-eluting stents as we know them today, have not been clearly established.
  
  
  METHODS
  We performed a retrospective cohort study by collecting detailed clinical and device data from all 150 consecutive patients who received IABP therapy in our institution between 2004 and 2009.
  
  
  RESULTS
  Thrombocytopenia occurred in 50%, fever in 36%, bleeding in 27%, and vascular embolic events in 1%. Thrombocytopenia was the most common adverse event and was not significantly associated with the use of antiplatelet agents. The presence of diabetes mellitus, elevated white blood cells at presentation, and longer duration of IABP were significantly associated with the development of fever. Furthermore, those who developed fever had higher in-hospital mortality (31% versus 16%; p = 0.0487).
  
  
  CONCLUSIONS
  In this contemporary cohort of IABP patients, complication rates of thrombocytopenia, fever and bleeding were relatively high but similar to prior studies, even in this current era of revascularization and antiplatelet medications.
authors.affiliation: The Heart Institute, Beth Israel Medical Center, 1st Avenue at 16th Street, New York, NY 10003, USA. lvalesmd@gmail.com
authors.forename: Lori
authors.initials: L
authors.lastname: Vales
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Kanei
authors.forename: Georges
authors.initials: G
authors.lastname: Ephrem
authors.forename: Deepika
authors.initials: D
authors.lastname: Misra
mesh_terms: D000368:Aged; D015331:Cohort Studies; D005260:Female; D005334:Fever / Q000453:epidemiology; D006470:Hemorrhage / Q000453:epidemiology; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D007423:Intra-Aortic Balloon Pumping / Q000009:adverse effects* / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012307:Risk Factors; D012770:Shock, Cardiogenic / Q000209:etiology / Q000628:therapy*; D013921:Thrombocytopenia / Q000453:epidemiology