title: Kikuchi-Fujimoto disease: an unusual association with acute renal failure.
abstract: Kikuchi-Fujimoto disease, also known as histiocytic necrotizing lymphadenitis of unknown etiopathogenesis, is a self-limited disease which frequently appears as feverish lymphadenomegaly, thus creating the need for differential diagnosis with lymphoma, systemic lupus erythematosus (SLE), infectious mononucleosis, cat-scratch disease, and toxoplasmosis with lymphonodal impairment. However, there are cases in which it may evolve with complications such as aseptic meningitis, cerebellar ataxia, and aseptic myocarditis. We are presenting a case of a 24-year-old man who had an initial picture of arthralgia, evening fever and adenomegaly. Kikuchi disease was diagnosed through lymph node biopsy with immunohistochemistry and evolves with severe systemic manifestations, such as pericarditis with cardiac tamponade, pneumonitis, hepatitis, and acute kidney failure - the latter has not been reported in literature yet. There was significant improvement of the clinical picture with prednisone.
authors.affiliation: Universidade Metropolitana de Santos, Brazil.
authors.forename: Amanda Feliciano da
authors.initials: AF
authors.lastname: Silva
authors.forename: Roberto
authors.initials: R
authors.lastname: Focaccia
authors.forename: Allan Constantino de
authors.initials: AC
authors.lastname: Oliveira
authors.forename: Angelo
authors.initials: A
authors.lastname: Sementilli
authors.forename: Gelvana Flávio Barreto
authors.initials: GF
authors.lastname: Reis
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D001706:Biopsy; D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D012720:Severity of Illness Index