title: Angiolymphoid hyperplasia with eosinophilia treated with vascular laser.
abstract: BACKGROUND
  Angiolymphoid hyperplasia with eosinophilia is a rare, benign disorder characterized by reddish-brown nodules and plaques in the dermis and the subcutaneous tissues, typically occurring on the neck and head. Surgical excision, corticosteroids, radiotherapy, and other therapies have been used, however, recurrences are common. Treatment with vascular lasers such as pulsed dye laser (PDL) or Nd:YAG seems to be a promising therapeutic option.
  
  
  OBJECTIVE
  To assess the efficacy and safety of PDL and combined sequential PDL-Nd:YAG laser in patients with ALHE.
  
  
  METHODS
  Three patients with ALHE were treated with PDL at 595-nm wavelength or with a combined sequential application of 595-nm PDL and 1,064-nm Nd:YAG wavelengths. Topical anesthetic was applied before laser treatment.
  
  
  RESULTS
  Complete resolution of the lesions was achieved in two patients with ALHE; a partial response was seen in one patient. No significant side-effects were reported.
  
  
  CONCLUSIONS
  We consider that PDL should be a first-line therapy for AHLE. Sequential application of PDL and Nd:YAG laser seems to show promising results, so it could be an interesting new treatment option.
authors.affiliation: Dermatology Department, Ramón y Cajal Hospital, Carretera Colmenar km 9.1, 28034, Madrid, Spain. raistlin_majere_19@hotmail.com
authors.forename: Javier
authors.initials: J
authors.lastname: Alcántara González
authors.forename: Pablo
authors.initials: P
authors.lastname: Boixeda
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Truchuelo Díez
authors.forename: Bibiana
authors.initials: B
authors.lastname: Pérez García
authors.forename: Pedro
authors.initials: P
authors.lastname: Jaén Olasolo
mesh_terms: D000328:Adult; D000368:Aged; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology / Q000601:surgery*; D004423:Ear; D005260:Female; D006801:Humans; D054025:Lasers, Dye / Q000627:therapeutic use*; D012074:Remission Induction; D016896:Treatment Outcome; D055815:Young Adult