title: Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans.
abstract: It has been thought that phosphorus in biominerals made of amorphous calcium carbonate (ACC) might be related to ACC formation, but no such phosphorus-containing compounds have ever been identified. Crustaceans use ACC biominerals in exoskeleton and gastroliths so that they will have easy access to calcium carbonate inside the body before and after molting. We have identified phosphoenolpyruvate and 3-phosphoglycerate, intermediates of the glycolytic pathway, in exoskeleton and gastroliths and found them important for stabilizing ACC.
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
authors.forename: Ai
authors.initials: A
authors.lastname: Sato
authors.forename: Seiji
authors.initials: S
authors.lastname: Nagasaka
authors.forename: Kazuo
authors.initials: K
authors.lastname: Furihata
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagata
authors.forename: Isao
authors.initials: I
authors.lastname: Arai
authors.forename: Kazuko
authors.initials: K
authors.lastname: Saruwatari
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Kogure
authors.forename: Shohei
authors.initials: S
authors.lastname: Sakuda
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Nagasawa
mesh_terms: D000818:Animals; D002113:Calcification, Physiologic; D002119:Calcium Carbonate / Q000737:chemistry / Q000378:metabolism*; D003445:Crustacea / Q000378:metabolism*; D005988:Glyceric Acids / Q000737:chemistry / Q000378:metabolism; D006019:Glycolysis; D009682:Magnetic Resonance Spectroscopy; D008855:Microscopy, Electron, Scanning; D010728:Phosphoenolpyruvate / Q000737:chemistry / Q000378:metabolism
chemical_list: D005988:Glyceric Acids; D010728:Phosphoenolpyruvate; C005156:3-phosphoglycerate; D002119:Calcium Carbonate