title: A novel fluorescent aptasensor for thrombin detection: using poly(m-phenylenediamine) rods as an effective sensing platform.
abstract: In this communication, we develop a novel fluorescent aptasensor for thrombin detection with the use of poly(m-phenylenediamine) (PMPD) rods as an effective sensing platform. This aptasensor exhibits extraordinarily high sensitivity with a detection limit as low as 100 pM and excellent selectivity.
authors.affiliation: State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022 Jilin, China.
authors.forename: Yingwei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xuping
authors.initials: X
authors.lastname: Sun
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D010655:Phenylenediamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013917:Thrombin / Q000032:analysis*
chemical_list: D052157:Aptamers, Nucleotide; D005456:Fluorescent Dyes; D010655:Phenylenediamines; C435915:poly(1,3-phenylenediamine); C081676:thrombin aptamer; D013917:Thrombin