title: Hematopoietic SCT for adult T-cell leukemia/lymphoma: a review.
abstract: Adult T-cell leukemia/lymphoma is a T-cell malignancy caused by the human T-cell lymphotropic virus type 1. The aggressive forms of the disease carry a poor prognosis with standard therapies. The role of high-dose treatment with blood and marrow transplantation has, therefore, been examined mainly by Japanese groups in the form of retrospective studies. In this study, we review the literature, discuss some of the challenges facing successful transplantation approaches and stress the need for more innovative studies including in the Western hemisphere.
authors.affiliation: Division of Hematological Malignancies and Blood and Marrow Transplantation, Roger Williams Medical Center, Providence, RI, USA.
authors.forename: M
authors.initials: M
authors.lastname: Jabbour
authors.forename: H
authors.initials: H
authors.lastname: Tuncer
authors.forename: J
authors.initials: J
authors.lastname: Castillo
authors.forename: J
authors.initials: J
authors.lastname: Butera
authors.forename: T
authors.initials: T
authors.lastname: Roy
authors.forename: J
authors.initials: J
authors.lastname: Pojani
authors.forename: M
authors.initials: M
authors.lastname: Al-Malki
authors.forename: A S
authors.initials: AS
authors.lastname: Al-Homsi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000601:surgery*; D008297:Male; D008875:Middle Aged