title: [Progress of the study of mechanism on drug induced kidney injury].
abstract: Drug-induced nephrotoxicity is very common in both new drug development and clinic practice. Various drugs can induce kidney injuries, including tubulointerstitial, glomerular and renal vascular disease. To investigate the mechanism of drug induced nephrotoxicity is important for risk reduction of new drug development, reasonable drug usage, early discovery and effective prevention/treatment of adverse effects in clinics.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Xue
authors.forename: Li-kun
authors.initials: LK
authors.lastname: Gong
authors.forename: Jin
authors.initials: J
authors.lastname: Ren
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000818:Animals; D000890:Anti-Infective Agents / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced*; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced; D009395:Nephritis, Interstitial / Q000139:chemically induced; D051437:Renal Insufficiency / Q000139:chemically induced
chemical_list: D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents