title: Fast adaptation of pre-operative patient specific models to real-time intra-operative volumetric data streams.
abstract: Image-guided catheter ablation therapy is becoming an increasingly popular treatment option for atrial fibrillation. Successful treatment relies on accurate guidance of the treatment catheter. Integration of high-resolution, pre-operative data with electrophysiology data and positional data from tracked catheters improves targeting, but lacks the means to monitor changes in the atrial wall. Intra-operative ultrasound provides a method for imaging the atrial wall, but the real-time, dynamic nature of the data makes it difficult to seamlessly integrate with the static pre-operative patient-specific model. In this work, we propose a technique which uses a self-organizing map (SOM) for dynamically adapting a pre-operative model to surface patch data. The surface patch would be derived from a segmentation of the anatomy in a real-time, intra-operative ultrasound data stream. The method is demonstrated on two regular geometric shapes as well as data simulated from a real, patient computed tomography dataset.
authors.affiliation: Mayo Clinic College of Medicine, Biomedical Imaging Resource, Rochester MN, USA.
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Cameron
authors.forename: Maryam E
authors.initials: ME
authors.lastname: Rettmann
authors.forename: David R
authors.initials: DR
authors.lastname: Holmes
authors.forename: Richard A
authors.initials: RA
authors.lastname: Robb
mesh_terms: D017115:Catheter Ablation / Q000379:methods*; D003198:Computer Simulation; D003199:Computer Systems; D006329:Heart Conduction System / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D011300:Preoperative Care; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D013382:Subtraction Technique; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014584:User-Computer Interface