title: Gastrointestinal carcinoid tumors: diagnosis and treatment.
abstract: Carcinoid tumors are malignancies originating from neuroendocrine cells, most commonly encountered in the gastrointestinal tract, in a rate of 64%, with the majority affecting the ileum. Certain genetic syndromes sometimes include carcinoid tumors in their phenotype. These malignancies may be rather asymptomatic, although occasionally they behave aggressively. They are typically diagnosed due to the effects of a locally advanced disease, or when producing symptoms because of hormone secretion (carcinoid syndrome). A better understanding of their molecular biology and behavior is demanded so that these tumors to be diagnosed precociously and managed effectively.
authors.affiliation: 4th Department of Surgery, University of Athens, School of Medicine, Attikon General Hospital, Athens, Greece. mixalislak@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Stamatakos
authors.forename: K
authors.initials: K
authors.lastname: Kontzoglou
authors.forename: C
authors.initials: C
authors.lastname: Sargedi
authors.forename: S
authors.initials: S
authors.lastname: Tsaknaki
authors.forename: R
authors.initials: R
authors.lastname: Iannescu
authors.forename: C
authors.initials: C
authors.lastname: Safioleas
authors.forename: V
authors.initials: V
authors.lastname: Kaitanidi
authors.forename: M
authors.initials: M
authors.lastname: Safioleas
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism / Q000652:urine; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D003937:Diagnosis, Differential; D013505:Digestive System Surgical Procedures; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D014943:Global Health; D006801:Humans; D015994:Incidence; D007421:Intestine, Small / Q000473:pathology*; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis / Q000628:therapy; D015282:Octreotide / Q000627:therapeutic use; D012383:Romania / Q000453:epidemiology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D014408:Biomarkers, Tumor; D015282:Octreotide