title: Intracerebral hemorrhage despite prophylactic administration of vitamin K in infants--two case reports.
abstract: The incidence of vitamin K deficiency in infancy has decreased markedly, due to prophylactic administration of vitamin K during the neonatal period. However, vitamin K deficiency bleeding may occur during or after the neonatal period despite prophylactic administration in Japan. Two cases are reported of intracranial hemorrhage associated with coagulopathy in full-term infants who had received prophylactic administration of vitamin K. More reliable methods for prophylactic administration should be established.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Fukuoka University, Jhonan-ku, Fukuoka, Japan. approachgogo@yahoo.co.jp
authors.forename: Mika
authors.initials: M
authors.lastname: Komatsu
authors.forename: Fuminari
authors.initials: F
authors.lastname: Komatsu
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tsugu
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Yahiro
authors.forename: Shinya
authors.initials: S
authors.lastname: Oshiro
authors.forename: Tomoko
authors.initials: T
authors.lastname: Fujita
authors.forename: Kazuko
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Tooru
authors.initials: T
authors.lastname: Inoue
mesh_terms: D001778:Blood Coagulation Disorders / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D002543:Cerebral Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017211:Treatment Failure; D014812:Vitamin K / Q000494:pharmacology* / Q000502:physiology / Q000627:therapeutic use; D006475:Vitamin K Deficiency Bleeding / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control*
chemical_list: D014812:Vitamin K