title: Sensitivity to secondhand smoke exposure predicts smoking susceptibility in 8-13-year-old never smokers.
abstract: OBJECTIVE
  To investigate the sensitivity to secondhand smoke exposure (SHSe) in preteens aged 8-13 years who have never smoked, and to determine whether it predicts smoking susceptibility.
  
  
  METHODS
  We assessed the sensitivity to SHSe using reactions commonly used for the assessment of sensitivity to the first-smoked cigarette (e.g., feeling dizzy), and investigated the factor structure of these reactions for the purpose of data reduction. We examined the association of each reaction measure and summary score with demographic characteristics and smoking susceptibility, using logistic regression and ordinal logistic regression.
  
  
  RESULTS
  One factor was identified that captured the physical and/or unpleasant reactions. Older preteens and preteens with more highly educated parents reported fewer reactions to SHSe. More African American preteens reported feeling relaxed or calm compared with all other racial/ethnic groups. Experiencing physical and/or unpleasant reactions to SHSe predicted lower risk for smoking susceptibility.
  
  
  CONCLUSIONS
  This was the first study to extend analytical methodology for sensitivity to active smoking to sensitivity to SHSe in youth who had never smoked. Results suggest a desensitization process with age and lower sensitivity to some reactions in preteens from more highly educated households. Preteens who have more aversive experiences with SHSe tend to be less susceptible to smoking than those who experience fewer aversive reactions. Assessment of sensitivity to SHSe is a novel approach to the study of cigarette use etiology and may contribute to better prediction of smoking initiation.
authors.affiliation: Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. schlaggc@psychiatry.wustl.edu
authors.forename: Christina N
authors.initials: CN
authors.lastname: Lessov-Schlaggar
authors.forename: Dennis R
authors.initials: DR
authors.lastname: Wahlgren
authors.forename: Sandy
authors.initials: S
authors.lastname: Liles
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Jones
authors.forename: Ming
authors.initials: M
authors.lastname: Ji
authors.forename: Suzanne C
authors.initials: SC
authors.lastname: Hughes
authors.forename: Gary E
authors.initials: GE
authors.lastname: Swan
authors.forename: Melbourne F
authors.initials: MF
authors.lastname: Hovell
mesh_terms: D000293:Adolescent; D002140:California / Q000453:epidemiology; D016009:Chi-Square Distribution; D002648:Child; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D016015:Logistic Models; D008297:Male; D011237:Predictive Value of Tests; D012306:Risk; D012907:Smoking / Q000453:epidemiology*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution