title: A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery.
abstract: Metastasis to the abdominal wall including port sites after laparoscopic surgery for colorectal cancer is rare. Resection of metastatic lesions may lead to greater survival benefit if the abdominal wall metastasis is the only manifestation of recurrent disease. A 57-year-old man, who underwent laparoscopic surgery for advanced mucinous adenocarcinoma of the cecum 6 years prior, developed a nodule in the surgical wound at the lower right abdomen. Although tumor markers were within normal limits, the metastasis to the abdominal wall and abdominal cavity from the previous cecal cancer was suspected. An abdominal computed tomography scan did not provide detective evidence of metastasis. (18)F-fluorodeoxyglucose positron emission/computed tomography ((18)F-FDG PET/CT) was therefore performed, which demonstrated increased (18)F-fluorodeoxyglucose uptake (maximum standardized uptake value: 3.1) in the small abdominal wall nodule alone. Histopathological examination of the resected nodule confirmed the diagnosis of metastatic mucinous adenocarcinoma. Prognosis of intestinal mucinous adenocarcinoma is reported to be poorer than that of non-mucinous adenocarcinoma. In conclusion, this case suggests an important role of (18)F-FDG PET/CT in early diagnosis and decision-making regarding therapy for recurrent disease in cases where a firm diagnosis of recurrent colorectal cancer is difficult to make.
authors.affiliation: Department of Gastroenterological Surgery, Toho University Medical Center, Omori Hospital, 6-11-1 Omori nishi, Tokyo, 143-8541, Japan. kingkong@med.toho-u.ac.jp
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Funahashi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Ushigome
authors.forename: Hironori
authors.initials: H
authors.lastname: Kaneko
mesh_terms: D034861:Abdominal Wall / Q000473:pathology* / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000556:secondary* / Q000601:surgery; D002430:Cecal Neoplasms / Q000556:secondary* / Q000601:surgery; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18