title: Microdosimetric comparison of scanned and conventional proton beams used in radiation therapy.
abstract: Multiple groups have hypothesised that the use of scanning beams in proton therapy will reduce the neutron component of secondary radiation in comparison with conventional methods with a corresponding reduction in risks of radiation-induced cancers. Loma Linda University Medical Center (LLUMC) has had FDA marketing clearance for scanning beams since 1988 and an experimental scanning beam has been available at the LLUMC proton facility since 2001. The facility has a dedicated research room with a scanning beam and fast switching that allows its use during patient treatments. Dosimetric measurements and microdosimetric distributions for a scanned beam are presented and compared with beams produced with the conventional methods presently used in proton therapy.
authors.affiliation: Department of Radiation Medicine, Loma Linda University Medical Center, 25 Westminster Bridge Way, Timonium, MD, USA. dicello@usna.edu
authors.forename: John F
authors.initials: JF
authors.lastname: Dicello
authors.forename: Bradford B
authors.initials: BB
authors.lastname: Gersey
authors.forename: Daila S
authors.initials: DS
authors.lastname: Gridley
authors.forename: George B
authors.initials: GB
authors.lastname: Coutrakon
authors.forename: David
authors.initials: D
authors.lastname: Lesyna
authors.forename: Vincent L
authors.initials: VL
authors.lastname: Pisacane
authors.forename: James B
authors.initials: JB
authors.lastname: Robertson
authors.forename: Reinhard W
authors.initials: RW
authors.lastname: Schulte
authors.forename: Jerry D
authors.initials: JD
authors.lastname: Slater
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Wroe
authors.forename: James M
authors.initials: JM
authors.lastname: Slater
mesh_terms: D010315:Particle Accelerators; D011522:Protons; D011874:Radiometry; D011879:Radiotherapy Dosage
chemical_list: D011522:Protons