title: Cortical modulation of the transient visual response at thalamic level: a TMS study.
abstract: The transient visual response of feline dorsal lateral geniculate nucleus (dLGN) cells was studied under control conditions and during the application of repetitive transcranial magnetic stimulation at 1 Hz (rTMS@1Hz) on the primary visual cortex (V1). The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing. On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles. These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.
authors.affiliation: Neuroscience and Motor Control Group (NEUROcom) and Biomedical Institute of A Coruña (INIBIC), University of A Coruña, A Coruña, Spain.
authors.forename: Nelson
authors.initials: N
authors.lastname: Espinosa
authors.forename: Jorge
authors.initials: J
authors.lastname: Mariño
authors.forename: Carmen
authors.initials: C
authors.lastname: de Labra
authors.forename: Javier
authors.initials: J
authors.lastname: Cudeiro
mesh_terms: D000818:Animals; D002415:Cats; D025461:Feedback, Physiological / Q000502:physiology; D005260:Female; D020647:Lateral Thalamic Nuclei / Q000166:cytology / Q000502:physiology*; D008297:Male; D010775:Photic Stimulation; D013997:Time Factors; D050781:Transcranial Magnetic Stimulation; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*