title: Phenazinolins A-E: novel diphenazines from a tin mine tailings-derived Streptomyces species.
abstract: Phenazinolins A-E (1-5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1-3 and the oxabicyclo[3.3.1]nonadienol moiety in 4 and 5), were isolated from tin mine tailings-derived Streptomyces diastaticus YIM DT26, with 1-3 exhibited appreciable cytotoxicity and antibiotic effects.
authors.affiliation: Key Laboratory for Microbial Resources, Ministry of Education, Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, PR China.
authors.forename: Zhang-Gui
authors.initials: ZG
authors.lastname: Ding
authors.forename: Ming-Gang
authors.initials: MG
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Ren
authors.forename: Jiang-Yuan
authors.initials: JY
authors.lastname: Zhao
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.forename: Qing-Zhong
authors.initials: QZ
authors.lastname: Wang
authors.forename: Xiao-Long
authors.initials: XL
authors.lastname: Cui
authors.forename: Hua-Jie
authors.initials: HJ
authors.lastname: Zhu
authors.forename: Meng-Liang
authors.initials: ML
authors.lastname: Wen
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D050296:Microbial Viability / Q000187:drug effects; D008906:Mining; D015394:Molecular Structure; D010879:Piperazines / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013302:Streptomyces / Q000737:chemistry* / Q000187:drug effects / Q000302:isolation & purification; D013329:Structure-Activity Relationship; D014001:Tin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010879:Piperazines; D014001:Tin; C012527:diphenazine