title: Oxyresveratrol protects against DNA damage induced by photosensitized riboflavin.
abstract: Riboflavin can be photosensitized to produce reactive oxygen species. In the present study, a DNA damage assay was developed based on the photo reaction of riboflavin. In this test system, oxyresveratrol showed higher DNA protective effect than the well-known antioxidants Trolox and ascorbic acid. The results suggest potential applications for oxyresveratrol as an anti-aging agent and a riboflavin stabilizer.
authors.affiliation: Department of Phamacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Manussanunt
authors.initials: M
authors.lastname: Chatsumpun
authors.forename: Taksina
authors.initials: T
authors.lastname: Chuanasa
authors.forename: Boonchoo
authors.initials: B
authors.lastname: Sritularak
authors.forename: Kittisak
authors.initials: K
authors.lastname: Likhitwitayawuid
mesh_terms: D004249:DNA Damage; D016166:Free Radical Scavengers / Q000494:pharmacology; D010777:Photochemistry; D010936:Plant Extracts / Q000494:pharmacology*; D017382:Reactive Oxygen Species; D012256:Riboflavin / Q000737:chemistry*; D013267:Stilbenes / Q000494:pharmacology*
chemical_list: D016166:Free Radical Scavengers; D010936:Plant Extracts; D017382:Reactive Oxygen Species; D013267:Stilbenes; C034912:puag-haad; D012256:Riboflavin