title: [Thymic uptake of 18FFDG following radioiodine ablation therapy].
abstract: We report the case of a 47 year-old woman with a history of non-Hodgkin's lymphoma. During the course of her disease, we performed various (18F)FDG PET/CT that identified several significant incidental findings. First, we incidentally identified a hypermetabolic nodule in the left thyroid lobe, whose final diagnosis was differentiated thyroid carcinoma. Second, metabolic activity was visualized in the thymus secondary to ablative treatment with radioiodine. This uptake disappeared in subsequent studies. Several papers have reported thymic rebound following chemotherapy but we have found only one case report of (18F)FDG uptake after radioiodine treatment. On the other hand, this case is of interest because it supports the benefit of studying the hypermetabolic thyroid nodules incidentally detected on the PET/CT performed for other reasons.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España. m_albala@hotmail.com
authors.forename: M D
authors.initials: MD
authors.lastname: Albalá González
authors.forename: E
authors.initials: E
authors.lastname: Martínez Gimeno
authors.forename: C
authors.initials: C
authors.lastname: Cárdenas Negro
authors.forename: A
authors.initials: A
authors.lastname: Allende Riera
authors.forename: D
authors.initials: D
authors.lastname: Cabello García
authors.forename: M
authors.initials: M
authors.lastname: De Sequera Rahola
authors.forename: J A
authors.initials: JA
authors.lastname: Uña Gorospe
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D005462:Fluorine Radioisotopes / Q000493:pharmacokinetics; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D033162:Incidental Findings; D007457:Iodine Radioisotopes / Q000493:pharmacokinetics* / Q000627:therapeutic use; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D008875:Middle Aged; D064847:Multimodal Imaging; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D036102:Peripheral Blood Stem Cell Transplantation; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013950:Thymus Gland / Q000000981:diagnostic imaging*; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D016606:Thyroid Nodule / Q000000981:diagnostic imaging; D014018:Tissue Distribution; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D005462:Fluorine Radioisotopes; D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18