title: Control of dynamics and molecular distribution in a self-spreading lipid bilayer using surface-modified metal nanoarchitectures.
abstract: The molecular distribution and spreading dynamics of self-spreading lipid bilayers can be tuned by surface-modified metallic nanoarchitectures. Interactions between lipids and molecules in the surface modification alter the self-spreading behavior at the gate regions between adjacent nanoarchitectures, leading to molecular filtering/concentrating effects and modification of the dynamics. The hydrophilic surface can tune the spreading velocity without changing the molecular distribution in the spreading bilayer, whereas the hydrophobic surface provides a molecular concentrating function to the nanogates. This indicates that a combination of unmodified/hydrophobic/hydrophilic nanoarchitectures has a wide range of potential applications since it can be used to independently control the self-spreading dynamics and the molecular distribution.
authors.affiliation: Department of Chemistry, Graduate School of Science, Hokkaido University, Kita, Sapporo, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Nabika
authors.forename: Masahiro
authors.initials: M
authors.lastname: Oowada
authors.forename: Kei
authors.initials: K
authors.lastname: Murakoshi
mesh_terms: D057927:Hydrophobic and Hydrophilic Interactions; D008051:Lipid Bilayers / Q000737:chemistry*; D053768:Metal Nanoparticles; D018625:Microscopy, Atomic Force; D008954:Models, Biological; D015394:Molecular Structure; D013499:Surface Properties
chemical_list: D008051:Lipid Bilayers