title: Hearing loss disorders associated with renal disease.
abstract: There are several syndromes in which both hearing and renal function are impaired. The two best known are branchio-oto-renal (BOR) syndrome and Alport syndrome. These are reviewed along with several other rarer syndromes. BOR is especially important since it is likely to be first recognized by the otolaryngologist because of the hearing and branchial anomalies. It is important for the practicing otolaryngologist to recognize these disorders and to ensure that renal problems are being treated. In addition, the syndromes discussed here are all hereditary and referral to a clinical geneticist may be helpful to the individual and family.
authors.forename: William J
authors.initials: WJ
authors.lastname: Kimberling
authors.forename: Nicolo
authors.initials: N
authors.lastname: Borsa
authors.forename: Richard J H
authors.initials: RJH
authors.lastname: Smith
mesh_terms: D019280:Branchio-Oto-Renal Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D024141:Collagen Type IV / Q000235:genetics; D003937:Diagnosis, Differential; D005817:Genetic Counseling; D040941:Heredity; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics; D009154:Mutation; D009394:Nephritis, Hereditary / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D009687:Nuclear Proteins / Q000235:genetics; D017027:Protein Tyrosine Phosphatases / Q000235:genetics; D012017:Referral and Consultation
chemical_list: D024141:Collagen Type IV; D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; C104381:EYA1 protein, human; D017027:Protein Tyrosine Phosphatases