title: [Recent progress in the study of cyclodextrin-based environment sensitive hydrogel].
abstract: This is a review of recent progress in the study on environment sensitive hydrogel based on cyclodextrin and their most recent and relevant applications in the intelligent drug delivery systems. Based on relevant literatures, the development of environment sensitive hydrogel responsive to physical, chemical and biochemical stimuli was introduced, involving their categorization, design principles, mechanism of action and potential application. Various new types of intelligent drug delivery system, which responds to various triggers, could be constructed by using the cyclodextrin-based environment sensitive hydrogel. They made it possible to control the drug release freely. Although these hydrogels are still at their research stage, they have attracted considerable interest in the intelligent drug delivery system.
authors.affiliation: Department of Pharmacy, Medical College of Chinese People's Armed Police Forces, Tianjin 300162, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yuan
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000180:Acrylic Resins; D003505:Cyclodextrins / Q000008:administration & dosage* / Q000737:chemistry; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D004339:Drug Compounding; D016503:Drug Delivery Systems; D004777:Environment; D020100:Hydrogels; D006863:Hydrogen-Ion Concentration; D008027:Light; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000737:chemistry; D011145:Polyvinyls / Q000008:administration & dosage / Q000737:chemistry; D011409:Propylene Glycols / Q000008:administration & dosage / Q000737:chemistry; D013696:Temperature
chemical_list: D000180:Acrylic Resins; D003505:Cyclodextrins; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D020100:Hydrogels; C116176:PEO-PPO-PEO; D011145:Polyvinyls; D011409:Propylene Glycols; C006912:carboxypolymethylene; D011092:Polyethylene Glycols