title: Adenocarcinoma of the upper esophagus.
abstract: Glandular heterotopia of the upper esophagus is a congenital abnormality that is frequently discovered during upper digestive tract endoscopy (in 0.26-4.9% of cases), but usually with no malignant potential. Indeed, adenocarcinoma of the upper esophagus related to such lesions is a rare entity. We report here the 27th observation of this rare type of tumor in an 87-year-old man complaining of cervical dysphagia. This adenocarcinoma had developed from an area of gastric heterotopia 3 cm below the upper sphincter of the esophagus. The treatment regimen was based on exclusive radiochemotherapy, which led to a complete endoscopic response at the end of treatment. The patient's symptom-free survival was six months and overall survival was 17 months from diagnosis. This case of a rare tumor of the upper esophagus raises the question of whether the detection and surveillance of this type of heterotopia would be useful and, thus, to be recommended.
authors.affiliation: Service de pathologie digestive, HIA Laveran, BP 60149, 13384 Marseille cedex 13, France.
authors.forename: A
authors.initials: A
authors.lastname: Bard
authors.forename: T
authors.initials: T
authors.lastname: Coton
authors.forename: C
authors.initials: C
authors.lastname: De Biasi
authors.forename: M
authors.initials: M
authors.lastname: Guisset
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000628:therapy; D000369:Aged, 80 and over; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male