title: Extraction of RNA from Intracellular Mycobacterium tuberculosis : Methods, Considerations, and Applications.
abstract: Pathogenicity in Mycobacterium tuberculosis may be thought of as a multifactorial process with both pathogen and host-response effector molecules contributing to the process of infection, leading either to immunopathology and disease or control of infection and long-term persistence. Little is known about this at a genetic level, but it is becoming recognized that bacterial virulence constitutes the correct temporal and spatial regulation of many genes that may be necessary for a particular phase in infection in response to specific environmental cues.
authors.forename: I M
authors.initials: IM
authors.lastname: Monahan
authors.forename: J A
authors.initials: JA
authors.lastname: Mangan
authors.forename: P D
authors.initials: PD
authors.lastname: Butcher