title: [Modern ideas about the role of polyunsaturated fatty acids in the diet of women and children: new aspects].
abstract: Literature data on biochemical functions and physiological significance of omega-3 polyunsaturated fatty acids (PUFA) nutrition of children and pregnant women have been analyzed. New own data about main metabolic functions of PUFA regulation of lipid peroxidation and forming of antioxidant system--in healthy term and preterm babies and pregnant women with preeclampsia are given. At the same time the data on the synthesis of 4th and 5th series leukotrienes in healthy and sick children and cell membrane fatty acids composition changes at different types of inflammation are shown. The hypothesis had been formulated about omega-3 PUFA possible participation in cell proliferation and programming role of their adequate intake at early age for providing health in older age periods. It was pointed also on the importance of correct relation of omega-6/omega-3 PUFA in the diet as the precursors of 4th and 5th series leukotrienes in the organism for prevention of hard and long lasting course of some invaliding diseases in children and successful course and pregnancy termination in women.
authors.forename: N M
authors.initials: NM
authors.lastname: Shilina
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D049109:Cell Proliferation; D002648:Child; D002675:Child, Preschool; D004032:Diet; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage* / Q000378:metabolism; D005260:Female; D006801:Humans; D015289:Leukotrienes / Q000096:biosynthesis; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005231:Fatty Acids, Unsaturated; D015289:Leukotrienes