title: c-Myb in Smooth Muscle Cells.
abstract: The proto-oncogene c-myb is a cellular homolog of a viral oncogene v-myb found in two independently derived avian acute leukemia viruses: avian myeloblastosis vn-us (AMV) and E26 leukemia virus (1). The myb gene is highly conserved in eukaryotes, and it usually consists of 15 exons spanning over 35 kb of genomic DNA (1).In humans, c-myb gene locus has been mapped to chromosome 6 (6q22-23) However, myb mRNA expressed in thymus contains transcripts originating from chromosome 17 (17q25), suggesting that an mtermolecular recombinant event may be involved in the formation of the mature protein (2).
authors.affiliation: Department of Biology, Massachusetis Institute of Technology, Cambridge, MA.
authors.forename: M
authors.initials: M
authors.lastname: Simons
authors.forename: R D
authors.initials: RD
authors.lastname: Rosenberg