title: [Chemical constituents of Swertia macrosperma].
abstract: OBJECTIVE
  To study the chemical constituents of Swertia macrosperma.
  
  
  METHODS
  The air-dried whole plants of Swertia macrosperma were extracted with boiling water. The extract was concentrated to a small amount of volume and extracted with petroleum ether, EtOAc and n-BuOH, successively. The compounds were isolated and purified by column chromatography from the EtOAc fraction, and identified based on spectral analyses (MS, 1H-NMR, 13C-NMR).
  
  
  RESULTS
  Thirteen compounds were isolated from S. macrosperma, and were characterized as norbellidifolin (1), 1-hydroxy-3,7, 8-trimethoxy-xanthone (2), norswertianolin (3), swertianolin (4), 1,3,7,8-tetrahydroxyxanthone-8-O-beta-D-glucopyranoside (5), swertiamatin (6), decentapicrin (7), coniferl aldehyde (8), sinapaldehyde (9), balanophonin (10), together with beta-sitosterol, daucosterol, and oleanolic acid .
  
  
  CONCLUSIONS
  Compounds 2, 4-10 were obtained from Swertia macrosperma for the first time.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
authors.forename: Hongling
authors.initials: H
authors.lastname: Wang
authors.forename: Changan
authors.initials: C
authors.lastname: Geng
authors.forename: Xuemei
authors.initials: X
authors.lastname: Zhang
authors.forename: Yunbao
authors.initials: Y
authors.lastname: Ma
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Jiang
authors.forename: Jijun
authors.initials: J
authors.lastname: Chen
mesh_terms: D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification; D029967:Swertia / Q000737:chemistry*
chemical_list: D010936:Plant Extracts