title: Immunosuppression after kidney transplantation.
abstract: Today kidney transplantation features excellent short-term outcomes with decreasing acute rejection episodes. In contrast, improvement of long-term allograft survival is much less impressive over the last decades. Thus, the goal of current immunosuppressive therapies is keeping the balance between the reduction of acute rejection episodes and organ specific and systemic side effects. With the development of a broad armamentarium of new immunosuppressive agents with different mechanisms of action, the minimization or avoidance of corticosteroids and calcineurin inhibitors became feasible.
authors.affiliation: Department of Nephrology, University Hospital, Heidelberg, Germany. lars.kihm@med.uni-heidelberg.de
authors.forename: L P
authors.initials: LP
authors.lastname: Kihm
authors.forename: M
authors.initials: M
authors.lastname: Zeier
authors.forename: C
authors.initials: C
authors.lastname: Morath
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D065095:Calcineurin Inhibitors; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation; D011182:Postoperative Care
chemical_list: D000305:Adrenal Cortex Hormones; D065095:Calcineurin Inhibitors; D007166:Immunosuppressive Agents