title: [Clinical analysis of 12 acute leukemia patients aged over 80 years].
abstract: The objective of this study was to explore the clinical features of acute leukemia patients aged over 80 years. 12 cases of acute leukemia patients aged over 80 years who were diagnosed from 2000 to 2010 years were analyzed retrospectively. 9 cases suffered from acute myelogenous leukemia and 3 cases were with acute lymphoblastic leukemia. All patients were with several complicated diseases and the general status was poor in most patients. 10 cases received individualized treatments. The results showed that 2 patients achieved complete remission, but in other patients was not observed remission and the mean survival time was 20 ± 16 weeks. In AML patients, the mean survival time was 27 ± 14 weeks which was obviously longer than that in other reports. The survival time in 3 ALL patients was shortest. In conclusion, survival time was prolonged obviously in AML patients well advanced of age after individualized treatments, but prognosis of ALL in aged patients was very poor, for whom there is no relatively effective treatment.
authors.affiliation: Department of Geriatric Hematology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Lin
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Zhu
authors.forename: Xue-Chun
authors.initials: XC
authors.lastname: Lu
authors.forename: Hui
authors.initials: H
authors.lastname: Fan
authors.forename: Su-Xia
authors.initials: SX
authors.lastname: Li
authors.forename: Bing
authors.initials: B
authors.lastname: Zhai
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Hai-Hong
authors.initials: HH
authors.lastname: Ran
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
mesh_terms: D000208:Acute Disease; D000369:Aged, 80 and over; D006801:Humans; D007938:Leukemia / Q000401:mortality / Q000628:therapy; D015470:Leukemia, Myeloid, Acute / Q000401:mortality / Q000628:therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome