title: An analysis of the magnetic resonance imaging and pathology of intracal lymphoplasmacyte-rich meningioma.
abstract: OBJECTIVE
  To discuss the MRI features of the intracranial lymphoplasmacyte-rich meningioma and the correlation between the MRI features and pathology.
  
  
  METHODS
  Review retrospectively the MRI and pathologic data of seven patients with lymphoplasmacyte-rich meningioma which were confirmed by surgery and pathology.
  
  
  RESULTS
  The seven cases of lymphoplasmacyte-rich meningioma were solitary, six cases demonstrated flat growth along the meninges, five cases had not yet formed specific nodules, and two cases exhibited irregular lobulation. Seven cases had no clear boundary, peritumoral brain edema was obvious and adjacent brain tissues were invaded to varying degrees. After plain MRI scans, the focuses of seven cases exhibited lower-isointense signal in T1WI, five cases revealed higher-isointense signal and two cases showed lower-isointense signal in T2WI. Enhancement scans demonstrated marked enhancement in seven cases, and the meninges in six cases thicken irregularly and extensively. Pathology showed the richness and diversity of cells, an infiltration containing plasma cells and lymphocytes, as well as the unequal areas of neoplastic spindle cells and meninge epithelial cells.
  
  
  CONCLUSIONS
  Lymphoplasmacyte-rich meningioma is a subtype meningioma of WHO I-grade, which is seldom seen and whose imaging appearances are varied from ordinary meningioma. Its features include growing flat along the meninges, irregular forms, unclear boundary, obvious edema, notable strengthening effect, usual invasion of adjacent brain tissues, and similar inflammation.
authors.affiliation: Department of Radiology, The Second Hospital of Lanzhou University, Lanzhou, China.
authors.forename: Jian-Li
authors.initials: JL
authors.lastname: Liu
authors.forename: Jun-Lin
authors.initials: JL
authors.lastname: Zhou
authors.forename: Yong-Heng
authors.initials: YH
authors.lastname: Ma
authors.forename: Chi
authors.initials: C
authors.lastname: Dong
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult