title: The measurement of cysteinyl leukotrienes in urine.
abstract: The cysteinyl leukotrienes, comprising leukotriene (LT) C4 and its major metabolites LTD4 and LTE4, are inflammatory lipid mediators derived from metabolism of arachidonic acid by 5-lipoxygenase. These leukotrienes have received considerable attention for their potential role in asthma and other inflammatory diseases. Since there is a potential role for these lipid mediators in both health and disease, the analysis of leukotrienes in biological fluids, especially urine, has generated significant interest.
authors.affiliation: National Jewish Medical and Research Center, Denver, CO.
authors.forename: J Y
authors.initials: JY
authors.lastname: Westcott
authors.forename: S E
authors.initials: SE
authors.lastname: Wenzel