title: Determination of glyphosate in foodstuff by one novel chemiluminescence-molecular imprinting sensor.
abstract: A novel chemiluminescence (CL) sensor for the determination of glyphosate (GLY) was made up based on molecularly imprinted polymer (MIP). The molecularly imprinted microspheres (MIMs) with a small dimension which possess extremely high surface-to-volume ratio were synthesized using precipitation polymerization with GLY as template. And then the MIMs were modified on glass sheets, which were placed at the bottom of wells of microplate as the recognizer. Subsequently, a highly selective and high throughput chemiluminescence (CL)-molecular imprinting (MI) sensor for detection of GLY was achieved. Influencing factors were investigated and optimized in detail. The method can perform 96 independent measurements sequentially in 10 min and the limit of detection (LOD) for GLY was 0.046 μg mL(-1). The relative standard deviation (RSD) for 11 parallel measurements of GLY was 4.68%. The results show that CL-MI sensor can become a useful analytical technology for quick molecular recognition.
authors.affiliation: School of Chemistry and Chemical Engineering, University of Jinan, Jinan, China.
authors.forename: Peini
authors.initials: P
authors.lastname: Zhao
authors.forename: Mei
authors.initials: M
authors.lastname: Yan
authors.forename: Congcong
authors.initials: C
authors.lastname: Zhang
authors.forename: Ruixue
authors.initials: R
authors.lastname: Peng
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Ma
authors.forename: Jinghua
authors.initials: J
authors.lastname: Yu
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000295:instrumentation*; D005504:Food Analysis / Q000295:instrumentation*; D005998:Glycine / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D008163:Luminescent Measurements / Q000295:instrumentation* / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D054802:Molecular Imprinting / Q000295:instrumentation*; D012015:Reference Standards; D012044:Regression Analysis; D015203:Reproducibility of Results; D013237:Stereoisomerism; D013696:Temperature; D000097797:Glyphosate
chemical_list: D005998:Glycine; D000097797:Glyphosate