title: [Fingerprints of Tongmai Keli by HPLC-DAD-MS].
abstract: In order to clarify the chemical composition of Tongmai Keli, a HPLC fingerprint was established, and the 22 peaks were characterized by LC-DAD-MS. The herbal sources of these peaks were assigned. The results implied that genistin 8-C-glucoside, puerarin, daidzein 8-C-apiosyl (1, 6)-O-glucoside, daidzin, and salvianolic acid B were the main constituents of in Tongmai Keli. Ten batches of Tongmai Keli produced by different pharmaceutical companies were analyzed. Although different batches contained similar compounds, the contents of major compounds were significantly different. The method established in this study could be used for the quality control of Tongmai Keli.
authors.affiliation: The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
authors.forename: Bei-Jia
authors.initials: BJ
authors.lastname: Li
authors.forename: Cheng
authors.initials: C
authors.lastname: Xiang
authors.forename: Xiu-Wei
authors.initials: XW
authors.lastname: Yang
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Wu
authors.forename: De-An
authors.initials: DA
authors.lastname: Guo
authors.forename: Min
authors.initials: M
authors.lastname: Ye
mesh_terms: D001572:Benzofurans / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D007529:Isoflavones / Q000032:analysis*; D030004:Ligusticum / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D029908:Pueraria / Q000737:chemistry; D011786:Quality Control; D027561:Salvia miltiorrhiza / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000379:methods; D053630:Depsides
chemical_list: D001572:Benzofurans; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D007529:Isoflavones; C013908:daidzin; C076944:salvianolic acid B; D053630:Depsides; C033607:puerarin