title: Solitary necrotic nodule of the liver: MR findings in 33 pathologically proved lesions.
abstract: OBJECTIVE
  To determine characteristic magnetic resonance (MR) imaging features of solitary necrotic nodule of the liver.
  
  
  METHODS
  MR images features of thirty-two patients (17 men, 15 women; mean age, 43 years; range, 24-76 years) with pathologically proved solitary necrotic nodule of the liver were retrospectively analyzed for number, size, signal intensity features and enhancement patterns.
  
  
  RESULTS
  A total of 33 lesions were identified. The mean diameter was 2.3cm (range 1.0-4.5cm). Thirty lesions (90.9%) were 1.0-3.0cm in diameter and only 3 lesions (9.1%) were larger than 3.0cm. On T1-weighted images, solitary necrotic nodule of the liver appeared hypointense in 31 lesions (93.9%) and isointense in 2 lesions (6.1%). On T2-weighted images, 12 (36.4%) lesions were hyperintense, 15 (45.4%) were isointense or invisible and 6 (18.2%) were hypointense. After injection of gadopentetate dimeglumine, all lesions were hypointense and none of them showed enhancement.
  
  
  CONCLUSIONS
  Solitary necrotic nodule of the liver is usually small with the size not exceed 3.0cm in diameter. Absence of enhancement on all dynamic phase after gadopentetate dimeglumine administration may be most characteristic feature of solitary necrotic nodule of the liver on MR images, which may help discriminate this entity from metastatic liver tumors and intrahepatic cholangiocarcinoma.
authors.affiliation: The Department of Special Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, No. 225, Changhai Road, Shanghai 200438, China. gengliehbh@sina.com
authors.forename: Li
authors.initials: L
authors.lastname: Geng
authors.forename: Chuan
authors.initials: C
authors.lastname: Lin
authors.forename: Bin
authors.initials: B
authors.lastname: Huang
authors.forename: Xing-An
authors.initials: XA
authors.lastname: Long
authors.forename: Bing-Hua
authors.initials: BH
authors.lastname: Dai
authors.forename: Wen-Ming
authors.initials: WM
authors.lastname: Cong
authors.forename: Jia-Mei
authors.initials: JM
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult