title: The left ventricle as the first site of uveal melanoma metastasis 13 years after treatment of the primary tumor.
abstract: Treatment of patients with metastatic uveal melanoma is very challenging because the tumor commonly spreads to the liver, surgical resection of metastases is rarely possible, and there is no standard effective systemic therapy. We report the case of a 38-year-old man, who presented with metastatic involvement of the left ventricle as the first site of uveal melanoma recurrence 13 years after treatment of his primary tumor. The metastatic tumor was considered unresectable. We describe the patient's medical management over the next 3 years, the course of his disease, and the results of our review of the literature.
authors.affiliation: Department of Melanoma/Medical Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
authors.forename: Nathalie A
authors.initials: NA
authors.lastname: Kolandjian
authors.forename: Sapna P
authors.initials: SP
authors.lastname: Patel
authors.forename: Nicholas E
authors.initials: NE
authors.lastname: Papadopoulos
authors.forename: Agop Y
authors.initials: AY
authors.lastname: Bedikian
mesh_terms: D000328:Adult; D006338:Heart Neoplasms / Q000473:pathology / Q000556:secondary*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology / Q000556:secondary; D011379:Prognosis; D014604:Uveal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary; D000098943:Uveal Melanoma