title: ESIPT-mediated photocycloadditions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for reaction screening.
abstract: Irradiation of 1,2-dimethyl-3-hydroxyquinolinone (DMQ) leads to excited state intramolecular proton transfer (ESIPT) generating a 3-oxidoquinolinium species which undergoes [3 + 2] photocycloaddition with dipolarophiles. A parallel, fluorescence quenching assay using a microplate format has been developed to evaluate fluorescence quenching of this species with a range of dipolarophiles.
authors.affiliation: Department of Chemistry, Photonics Center, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
authors.forename: Bing
authors.initials: B
authors.lastname: Xia
authors.forename: Baudouin
authors.initials: B
authors.lastname: Gerard
authors.forename: Danielle M
authors.initials: DM
authors.lastname: Solano
authors.forename: Jiandi
authors.initials: J
authors.lastname: Wan
authors.forename: Guilford
authors.initials: G
authors.lastname: Jones
authors.forename: John A
authors.initials: JA
authors.lastname: Porco
mesh_terms: D005419:Flavonoids / Q000737:chemistry*; D005453:Fluorescence; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D055668:Photochemical Processes; D011522:Protons; D015363:Quinolones / Q000737:chemistry* / Q000528:radiation effects
chemical_list: D005419:Flavonoids; D011522:Protons; D015363:Quinolones