title: PAIRing for distal Igh locus V(D)J recombination.
abstract: In this issue of Immunity Ebert et al. (2011) defined the lineage- and stage-specific Pax5-dependent cis-sequences termed PAIR elements in the distal region of the mouse heavy chain immunoglobulin locus (Igh). These sequences may have a role in long-range IgH V(D)J recombination.
authors.affiliation: Howard Hughes Medical Institute, The Children's Hospital, The Immune Disease Institute, Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
authors.forename: Chunguang
authors.initials: C
authors.lastname: Guo
authors.forename: Frederick W
authors.initials: FW
authors.lastname: Alt
authors.forename: Cosmas
authors.initials: C
authors.lastname: Giallourakis