title: Cardiac surgery in a patient with paroxysmal nocturnal hemoglobinuria.
abstract: A 44-year-old woman, who had been diagnosed with paroxysmal nocturnal hemoglobinuria, presented with chest pain. Angiography revealed critical distal left main stenosis and proximal stenoses of the left anterior descending and circumflex arteries. Prophylactic antibiotics, infusion of blood products and mannitol intraoperatively, and antithrombotic therapy postoperatively ensured a good outcome of coronary artery bypass graft surgery under cardiopulmonary bypass.
authors.affiliation: Department of Cardiothoracic Surgery, Royal Perth Hospital, Perth, Western Australia. sharonchu@gmail.com
authors.forename: Sharon H L
authors.initials: SH
authors.lastname: Chu
authors.forename: David
authors.initials: D
authors.lastname: Andrews
authors.forename: Yuki
authors.initials: Y
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D019072:Antibiotic Prophylaxis; D001803:Blood Transfusion; D002315:Cardiopulmonary Bypass; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006801:Humans; D008353:Mannitol / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D008353:Mannitol