title: Dehydrogenative [4 + 2] cycloaddition of formamides with alkynes through double C-H activation.
abstract: Formamides having 1-arylalkyl groups on nitrogen undergo an unprecedented dehydrogenative [4 + 2] cycloaddition reaction with alkynes via nickel/AlMe(3) cooperative catalysis to give highly substituted dihydropyridone derivatives in good yields. Notably, the transformation proceeds through double functionalization of C(sp(2))-H and C(sp(3))-H bonds in the formamides.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. yoshiakinakao@npc05.mbox.media.kyoto-u.ac.jp
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao
authors.forename: Eiji
authors.initials: E
authors.lastname: Morita
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Idei
authors.forename: Tamejiro
authors.initials: T
authors.lastname: Hiyama