title: [Photo-onycholysis observed in connection with doxycycline for malaria prophylaxis].
abstract: We present two cases of phototoxic onycholysis secondary to doxycycline treatment as malaria prophylaxis. Onycholysis is a rare side-effect to treatment with doxycycline and other tetracyclines. Some physicians are unaware of this risk. Due to the increasing travel activity to malaria endemic regions, it is important to be aware of the side effects - including onycholysis - following the use of tetracyclines and it is essential to inform the patients of such effects. Spontaneous recovery follows within a few months after discontinuing the drug and there is no need for further treatment.
authors.affiliation: Dermato-venerologisk Afdeling, Bispebjerg Hospital, Denmark. trapwolf@hotmail.com
authors.forename: Hanne Trap
authors.initials: HT
authors.lastname: Wolf
authors.forename: Cristel Maria
authors.initials: CM
authors.lastname: Sørensen
authors.forename: Helle Kielberg
authors.initials: HK
authors.lastname: Larsen
mesh_terms: D000962:Antimalarials / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000009:adverse effects*; D005260:Female; D006801:Humans; D054039:Onycholysis / Q000139:chemically induced* / Q000175:diagnosis; D012552:Schistosomiasis / Q000175:diagnosis; D013472:Sunlight; D014195:Travel
chemical_list: D000962:Antimalarials; D004318:Doxycycline