title: [Cardiovascular manifestations of seronegative inflammatory spondyloarthropathies].
abstract: Cardiovascular manifestations of seronegative spondyloarthropathies represent an important clinical problem which has not been fully elucidated. Clinically significant cardiovascular symptoms are present in 10% of patients with ankylosing spondylitis (AS), usually in the case of long-standing disease. The following echocardiographic abnormalities have been reported in AS: ascending aortitis, aortic insufficiency (1-34%), mitral insufficiency (1-76%), mitral valve prolapse (5.7-10%), and diastolic dysfunction (20-50%). Abnormalities of the cardiac conduction system may develop in 1% to 33% of AS patients as a consequence of postinflammatory scarring of the myocardium. Cardiovascular diseases are the leading cause of death (36.2%) of patients with psoriatic arthritis (PsA). The risk of death in PsA is 1.3 times greater than in the general population. The following echocardiographic abnormalities can be seen in PsA: fibrinous pericarditis (18.2%), myocarditis (15.9%), and valvular disease (5.7%). Diastolic dysfunction in PsA correlates with the presence of articular lesions and duration of psoriasis. The importance of a thorough investigation of the cardiovascular system in patients with seronegative spondyloarthropathies is emphasized.
authors.affiliation: Klinika Reumatologii i Chorób Wewnetrznych Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1, 71-252 Szczecin.
authors.forename: Hanna
authors.initials: H
authors.lastname: Przepiera-Bedzak
authors.forename: Iwona
authors.initials: I
authors.lastname: Brzosko
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Peregud-Pogorzelska
authors.forename: Marek
authors.initials: M
authors.lastname: Wódecki
authors.forename: Marek
authors.initials: M
authors.lastname: Brzosko
mesh_terms: D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012698:Serologic Tests; D025242:Spondylarthropathies / Q000150:complications*