title: [Clinical experience with cold-preservation of venous and arterial allografts. long-term outcomes].
abstract: BACKGROUND
  Venous and arterial allografts extend the possibilities of peripheral arterial disease as well as vascular prosthesis infections treatment.
  
  
  METHODS
  Between 10/1997 and 1/2009 we used 112 allogeneic vessels (30 arteries, 82 veins) in 104 patients. Venous allografts were used for 82 reconstructions in 75 patients (M/F 41/34, aged 41-85 years, median 66 years) with critical limb ischemia and no suitable autogenous venous material. Arterial allografts were used in 9 patients (M/F 8/1, aged 56-77 years, median 63 years) with aortoiliac prosthetic infections or mycotic abdominal aortic aneurysms and in 20 transplanted patients (M/F 11/9, aged 32-67 years, median 56 years) with aortoiliac atherosclerotic disease.
  
  
  RESULTS
  Patients survival rate after allovenous bypasses was 92% at 1 year and 78% at 3 years. Limb salvage rate was 67% at 1 year and 53% and 3 years. Secondary patency rate was 48% at 1 year and 27% at 3 years. Patient survival rate after alloarterial bypasses was 86% at 1 year and 69% at 3 years. No signs of arterial grafts aneurysmal formation and no need for secondary intervention of any arterial reconstruction was observed during the follow up period in any patient after alloarterial transplantation.
  
  
  CONCLUSIONS
  Cold-stored venous and arterial allografts are suitable alternative conduits for limb salvage procedures, vascular prosthesis infections as well as for arterial reconstructions in transplanted patients.
authors.affiliation: Klinika transplantacní chirurgie, Institut klinické a experimentální medicíny, Praha. ivmi@ikem.cz
authors.forename: I
authors.initials: I
authors.lastname: Matia
authors.forename: M
authors.initials: M
authors.lastname: Adamec
authors.forename: L
authors.initials: L
authors.lastname: Janousek
authors.forename: K
authors.initials: K
authors.lastname: Lipár
authors.forename: T
authors.initials: T
authors.lastname: Marada
authors.forename: D
authors.initials: D
authors.lastname: Klein
authors.forename: P
authors.initials: P
authors.lastname: Baláz
authors.forename: M
authors.initials: M
authors.lastname: Varga
authors.forename: J
authors.initials: J
authors.lastname: Chlupác
authors.forename: S
authors.initials: S
authors.lastname: Rokosný
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001014:Aortic Aneurysm / Q000601:surgery; D001158:Arteries / Q000637:transplantation*; D003080:Cold Temperature; D015925:Cryopreservation; D005260:Female; D006085:Graft Survival; D006801:Humans; D007511:Ischemia / Q000601:surgery; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000601:surgery; D014184:Transplantation, Homologous; D014654:Vascular Patency; D014680:Veins / Q000637:transplantation*