title: New insights into oncogenic stress.
abstract: Expression of oncogenes in otherwise normal cells often leads to the activation of anti-oncogenic pathways through a poorly understood process described as 'oncogenic stress'. A new study implicates the Jnk pathway signaling in the activation of p53 in response to both K-Ras and Neu oncogene expression.
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Haigis
authors.forename: Alejandro
authors.initials: A
authors.lastname: Sweet-Cordero
mesh_terms: D000818:Animals; D002453:Cell Cycle; D016922:Cellular Senescence; D004249:DNA Damage; D015972:Gene Expression Regulation, Neoplastic; D016147:Genes, Tumor Suppressor; D018734:Genes, erbB-2; D016158:Genes, p53; D011905:Genes, ras; D006801:Humans; D020935:MAP Kinase Signaling System; D051379:Mice; D009369:Neoplasms / Q000517:prevention & control; D009857:Oncogenes; D011230:Precancerous Conditions / Q000235:genetics*