title: The way of the germline, its developmental cycle and epigenetic network.
abstract: The long-awaited second edition of the International Symposium on "Epigenome Network, Development and Reprogramming of Germ Cells" hosted by Hiroyuki Sasaki took place at the Kyushu University School of Medicine, in Fukuoka, Japan from 22 to 24 November 2010. This meeting brought together again the crème de la crème of the Japanese research community investigating germline development, reprogramming and genetic networks as well as eminent international scientists. Novel trend concepts including the "reprogramming expressway", "canalization", "licensing", "epigenetic barrier", "flex points" and "hydroxymethylation" were introduced and discussed in the context of development, reprogramming and pluripotency.
authors.affiliation: Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2300 ZC Leiden, The Netherlands. lopes@lumc.nl
authors.forename: Susana M
authors.initials: SM
authors.lastname: Chuva de Sousa Lopes
authors.forename: Bernard A J
authors.initials: BA
authors.lastname: Roelen
mesh_terms: D000818:Animals; D065150:Cellular Reprogramming; D042002:Chromatin Assembly and Disassembly / Q000235:genetics; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D005718:Gametogenesis / Q000235:genetics; D005854:Germ Cells / Q000254:growth & development*; D006801:Humans; D051379:Mice; D039904:Pluripotent Stem Cells / Q000502:physiology; D034622:RNA Interference; D051381:Rats; D012733:Sex Differentiation / Q000235:genetics