title: Narrow-band imaging endoscopy with and without magnification in diagnosis of colorectal neoplasia.
abstract: OBJECTIVE
  To evaluate the diagnostic efficacies of narrow-band imaging (NBI) endoscopy with and without high magnification in distinguishing neoplasia from non-neoplasia colorectal lesions.
  
  
  METHODS
  A total of 118 patients with 123 colorectal lesions examined by NBI endoscopy in the Zhejiang Provincial People's Hospital from September 2008 to April 2010 were enrolled in this study. These lesions were classified by pit pattern and capillary pattern, and then assessed by histopathology.
  
  
  RESULTS
  Ten lesions not meeting the diagnostic criteria were excluded, the overall diagnostic accuracy of NBI endoscopy in distinguishing neoplasia from non-neoplasia colorectal lesions was 91.2% (103/113), and that of NBI endoscopy with and without high magnification was 93.0% (40/43) and 90.0% (63/70), respectively. Both were significantly higher than that of conventional colonoscopy reported in the literature (P<0.05), but there was no significant difference between the two groups (P>0.05).
  
  
  CONCLUSIONS
  Besides NBI magnifying endoscopy, NBI endoscopy without magnification may also be used to distinguish neoplasia from non-neoplasia colorectal lesions.
authors.affiliation: Department of Gastroenterology, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China.
authors.forename: Qing-Jie
authors.initials: QJ
authors.lastname: Zhou
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Yang
authors.forename: Bao-Ying
authors.initials: BY
authors.lastname: Fei
authors.forename: Qi-Shun
authors.initials: QS
authors.lastname: Xu
authors.forename: Wei-Quan
authors.initials: WQ
authors.lastname: Wu
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Ruan
mesh_terms: D000328:Adult; D000368:Aged; D003111:Colonic Polyps / Q000175:diagnosis* / Q000473:pathology; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged