title: [Simultaneous determination of 56 organochlorine and pyrethroid pesticides in traditional Chinese medicines by GC coupled with dual-tower and dual-column].
abstract: The paper is to report the establishment of a method for the determination of multi-residue organochlorine and pyrethroid pesticides in traditional Chinese medicines (TCMs). Fifty-six pesticides were extracted by high-speed homogenization, and then purified through gel permeation chromatography (GPC) and solid phase extraction (SPE) cartridges. The residues were simultaneously identified and quantified by GC-ECD equipped with dual tower, dual column and two micro-ECD detectors. The analytical performance was demonstrated by the analysis of 3 TCMs samples' extracts, spiked at three concentration levels for each pesticide. In general, the recoveries ranging from 70% to 110%, with relative standard deviations (RSDs) better than 15%, were obtained. The limit of detection (LOD) for most of the targeted pesticides tested was below 0.01 mg kg(-1). The method had good extraction efficiency, purification effect and good reproducibility, which could be applied to the determination of organochlorine and pyrethroid pesticide residues in the routine analysis of TCMs.
authors.affiliation: Department of Traditional Chinese Medicine, Shanghai Institute for Food and Drug Control, Shanghai 201203, China.
authors.forename: Zheng-wei
authors.initials: ZW
authors.lastname: Jia
authors.forename: Xiu-hong
authors.initials: XH
authors.lastname: Mao
authors.forename: Shui
authors.initials: S
authors.lastname: Miao
authors.forename: Ji-wei
authors.initials: JW
authors.lastname: Lu
authors.forename: Ke
authors.initials: K
authors.lastname: Chen
authors.forename: Ke
authors.initials: K
authors.lastname: Wang
authors.forename: Shen
authors.initials: S
authors.lastname: Ji
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D002850:Chromatography, Gel; D004340:Drug Contamination; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D057230:Limit of Detection; D010573:Pesticide Residues / Q000032:analysis*; D011722:Pyrethrins / Q000032:analysis*; D015203:Reproducibility of Results; D052616:Solid Phase Extraction
chemical_list: D004365:Drugs, Chinese Herbal; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D011722:Pyrethrins