title: Hydroxyurea dose impacts hematologic parameters in polycythemia vera and essential thrombocythemia but does not appreciably affect JAK2-V617F allele burden.
authors.forename: Ilana Renault
authors.initials: IR
authors.lastname: Zalcberg
authors.forename: Jackline
authors.initials: J
authors.lastname: Ayres-Silva
authors.forename: Alexandre Mello
authors.initials: AM
authors.lastname: de Azevedo
authors.forename: Cristiana
authors.initials: C
authors.lastname: Solza
authors.forename: Adelmo
authors.initials: A
authors.lastname: Daumas
authors.forename: Martin
authors.initials: M
authors.lastname: Bonamino
mesh_terms: D000483:Alleles; D000970:Antineoplastic Agents / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005787:Gene Frequency; D006098:Granulocytes / Q000378:metabolism; D006403:Hematologic Tests; D006801:Humans; D006918:Hydroxyurea / Q000494:pharmacology*; D053614:Janus Kinase 2 / Q000235:genetics* / Q000378:metabolism; D017354:Point Mutation; D011087:Polycythemia Vera / Q000097:blood* / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics*; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D013920:Thrombocythemia, Essential / Q000097:blood* / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; D053614:Janus Kinase 2; D006918:Hydroxyurea