title: [Inhibitory effect of baicalin on germ tube formation and adhesion of Candida albicans].
abstract: OBJECTIVE
  To investigate the effects of baicalin against Candida albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells.
  
  
  METHODS
  Various concentrations of baicalin (100, 50, 10 mg x L(-1)) were incubated with C. albicans suspension, the mixed suspension of C. albicans and human buccal epitherial cells, the mixed suspension of C. albicans and vaginal epitherial cells, respectively. The effects of baicalin on C. albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells were then assessed microscopically.
  
  
  RESULTS
  All concentrations of baicalin could inhibit C. albicans germ tube formation, and adherent to buccal epitherial and vaginal epitherial cells,while there was no significant difference between standard and clinical strains.
  
  
  CONCLUSIONS
  Baicalin could inhibit C. albicans germ tube formation, and adherence to buccal epitherial and vaginal epitherial cells.
authors.affiliation: School of Integrated Taditional and Westen Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China. ahwcz63@sina.com
authors.forename: Changzhong
authors.initials: C
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Feng
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Zhang
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhu
authors.forename: Chuanqi
authors.initials: C
authors.lastname: Xie
authors.forename: Huijuan
authors.initials: H
authors.lastname: Cheng
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Yun
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development / Q000502:physiology*; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology*; D002610:Cheek / Q000382:microbiology; D004847:Epithelial Cells / Q000382:microbiology; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D006801:Humans; D009061:Mouth Mucosa / Q000382:microbiology; D014621:Vagina / Q000382:microbiology; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids; C038044:baicalin