title: Asymmetric segregation: the shape of things to come?
abstract: Yeast mother cells pay a sacrifice during budding: they keep the extrachromosomal rDNA circles (ERCs) so that their buds have a full lifespan ahead. Two new studies indicate that retention of ERCs in mother cells occurs not by tethering to the nuclear periphery but rather by the simple rules of diffusion in a time-limited and complex landscape.
authors.affiliation: Buck Institute for Research on Aging, Novato, CA 94945, USA. bkennedy@buckinstitute.org
authors.forename: Brian K
authors.initials: BK
authors.lastname: Kennedy
authors.forename: Mark A
authors.initials: MA
authors.lastname: McCormick
mesh_terms: D002455:Cell Division; D004058:Diffusion; D015966:Gene Expression Regulation, Fungal / Q000502:physiology*; D012331:RNA, Fungal / Q000502:physiology; D012335:RNA, Ribosomal / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics* / Q000378:metabolism; D013997:Time Factors
chemical_list: D012331:RNA, Fungal; D012335:RNA, Ribosomal