title: Combined penetrating keratoplasty and implantation of iris prosthesis intraocular lenses after ocular trauma.
abstract: OBJECTIVE
  To report the outcomes of implantation of intraocular lenses (IOLs) with a prosthetic iris to correct traumatic iris deficiency.
  
  
  METHODS
  Department of Ophthalmology, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
  
  
  METHODS
  Case series.
  
  
  METHODS
  The medical records of consecutive patients who had had implantation of an Ophtec or Morcher IOL combined with corneal transplantation were retrospectively reviewed. Preoperative data collected included demographics, etiology of the iris deficiency, previous surgeries, preoperative eye pathology, and visual acuity. Operative data and postoperative outcomes included visual acuity, subjective perception of glare and photophobia, and postoperative complications.
  
  
  RESULTS
  The records of 11 patients were reviewed. The corrected distance visual acuity improved from 2.39 logMAR ± 0.53 (SD) preoperatively to 1.50 ± 1.11 logMAR postoperatively (P=.0037). Four (36.4%) of 9 patients reported an improvement in glare sensation; 5 (45.5%) reported no change in glare (P=.99). Postoperative complications included 2 graft rejection episodes in 2 patients during the first year after surgery, 1 case of increased inflammation that required removal of the IOL, and 2 cases of new-onset glaucoma. At the last follow-up visit, the centration and positioning of the IOLs were excellent. There were no cases of IOL dislocation, macular edema, or retinal detachment.
  
  
  CONCLUSIONS
  Implantation IOLs with a prosthetic iris in traumatic aniridia improved visual acuity significantly in most patients and reduced photophobia and glare symptoms in many cases. Graft rejection, glaucoma, and postoperative inflammation are possible complications.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada. raneen_sh_mash@hotmail.com
authors.forename: Raneen Shehadeh
authors.initials: RS
authors.lastname: Mashor
authors.forename: Irit
authors.initials: I
authors.lastname: Bahar
authors.forename: Igor
authors.initials: I
authors.lastname: Kaiserman
authors.forename: Amy Lauren
authors.initials: AL
authors.lastname: Berg
authors.forename: Allan
authors.initials: A
authors.lastname: Slomovic
authors.forename: David S
authors.initials: DS
authors.lastname: Rootman
mesh_terms: D000328:Adult; D000368:Aged; D001187:Artificial Organs; D005131:Eye Injuries / Q000601:surgery*; D005260:Female; D019466:Glare; D006801:Humans; D007498:Iris / Q000293:injuries*; D015948:Keratoplasty, Penetrating; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D020795:Photophobia / Q000503:physiopathology; D011183:Postoperative Complications; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult