title: Study on ionic liquid-based ultrasonic-assisted extraction of biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill.
abstract: The ionic liquid-based ultrasonic-assisted extraction (ILUAE) has been successfully applied in extracting four biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill. Seventeen different types of ionic liquids with different cations and anions have been investigated. 0.8 M 1-lauryl-3-methylimidazolium bromide ([C12mim]Br) solution was selected as solvent. In addition, the ultrasonic parameters including ultrasonic power, time for ultrasonic treatment and solid-liquid ratio have been optimized by Response Surface Method (RSM). Compared with the conventional solvent extraction, the efficiency of the approach proposed in this work is about 3.5 times as much as that of the conventional solvent extraction method. With the proposed extraction method, the extraction time has been reduced to 30 min, whereas the conventional extraction method requires about 6.0 h. The experimental results presented in this work indicate that the ILUAE is a simple and efficient technique for sample preparation. The proposed method is reproducible.
authors.affiliation: Key Laboratory of Forest Plant Ecology, Northeast Forestry University, 150040 Harbin, PR China.
authors.forename: Chun-hui
authors.initials: CH
authors.lastname: Ma
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Liu
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Yuan-gang
authors.initials: YG
authors.lastname: Zu
authors.forename: Shu-ya
authors.initials: SY
authors.lastname: Wang
authors.forename: Rong-rui
authors.initials: RR
authors.lastname: Zhang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D034242:Cyclooctanes / Q000302:isolation & purification*; D005638:Fruit / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D017705:Lignans / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry; D011083:Polycyclic Compounds / Q000302:isolation & purification*; D032141:Schisandra / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*; D013997:Time Factors; D014465:Ultrasonics
chemical_list: D034242:Cyclooctanes; D052578:Ionic Liquids; D017705:Lignans; D010936:Plant Extracts; D011083:Polycyclic Compounds; C034734:schizandrin A; C011105:schizandrin