title: [Clinical features of acute cerebral blood circulation disorders in young patients with non-differential dysplasia of the connective tissue].
abstract: One hundred young patients (aged 17-45 years) with acute cerebral blood circulation disorders (ACBCD) have been studied. Phenotypic signs of non-differential dysplasia of the connective tissue (NDDCT) have been found in 50 patients (the main group) and other 50 patients had no clinical signs of NDDCT (the comparison group). Patients underwent a complex clinico-neurological, instrumental and laboratory study. In young patients with NDDCT, transient ischemic attacks were observed in 14%, ischemic strokes in 66%, hemorrhagic strokes in 20%. Risk factors characteristic of young patients with ACBCD have been singled out. The higher content of free oxyproline, the distinct positive dynamics (the reduction of clinical symptoms severity during the acute phase of stroke) and the significantly better restoration of lost functions were observed in patients with NDDCT compared to patients without NDDCT.
authors.forename: N V
authors.initials: NV
authors.lastname: Pizova
authors.forename: A N
authors.initials: AN
authors.lastname: Dmitriev
authors.forename: P A
authors.initials: PA
authors.lastname: Chizhov
authors.forename: V A
authors.initials: VA
authors.lastname: Tabakov
authors.forename: S D
authors.initials: SD
authors.lastname: Prozorovskaia
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002560:Cerebrovascular Circulation; D003238:Connective Tissue / Q000002:abnormalities*; D003240:Connective Tissue Diseases / Q000097:blood / Q000150:complications*; D005260:Female; D006801:Humans; D006909:Hydroxyproline / Q000097:blood; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D013577:Syndrome; D055815:Young Adult
chemical_list: D006909:Hydroxyproline