title: Pd-catalyzed α-arylation of nitriles and esters and γ-arylation of unsaturated nitriles with TMPZnCl·LiCl.
abstract: Using TMPZnCl·LiCl as a kinetically highly active base, nitriles and esters undergo a Pd-catalyzed α-arylation under mild conditions. Remarkably, in the case of α,β- or β,γ-unsaturated nitriles, a regioselective γ-arylation or a γ-alkenylation is observed.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377, München, Germany.
authors.forename: Stphanie
authors.initials: S
authors.lastname: Duez
authors.forename: Sebastian
authors.initials: S
authors.lastname: Bernhardt
authors.forename: Johannes
authors.initials: J
authors.lastname: Heppekausen
authors.forename: Fraser F
authors.initials: FF
authors.lastname: Fleming
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel