title: Atypical subtrochanteric fractures after long-term bisphosphonate therapy.
abstract: There have been many reports published in recent years on atypical subtrochanteric fractures after long-term bisphosphonates therapy. In a description of a few series of cases, fractures of typical clinical course and radiological image have been documented. These fractures are estimated as very rare (2.3 per 10,000 patient-years). It is suggested that a subsequent use of steroids or proton pump inhibitors with bisphosphonates may increase the risk of fracture occurrence.
authors.affiliation: Department of Bone and Joint Disease, WNZ, Collegium Medicum of the jagiellonian University, Kraków, Poland. czerwinski@kcm.pl
authors.forename: Edward
authors.initials: E
authors.lastname: Czerwiński
mesh_terms: D019386:Alendronate / Q000009:adverse effects*; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D004347:Drug Interactions; D004359:Drug Therapy, Combination / Q000009:adverse effects; D006620:Hip Fractures / Q000139:chemically induced*; D006801:Humans; D054328:Proton Pump Inhibitors / Q000008:administration & dosage; D013256:Steroids / Q000008:administration & dosage
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D054328:Proton Pump Inhibitors; D013256:Steroids; D019386:Alendronate