title: Fulminant hepatitis and glomerulonephritis--a rare presentation of hepatitis A virus infection.
abstract: OBJECTIVE
  We report a case of fulminant hepatitis and glomerulonephritis by Hepatitis A virus infection.
  
  
  METHODS
  We observed the patient's clinical course and analyzed his data retrospectively.
  
  
  RESULTS
  The three-year-old boy presented with features of acute renal failure and stage 2 hepatic encephalopathy. Renal biopsy showed diffuse mesangioproliferative glomerulonephritis with immunoglobulin M and complement 3 deposition. After receiving supportive treatment for over 6 weeks, the hepatic and renal function became normal. Renal biopsy after 3 months was normal.
  
  
  CONCLUSIONS
  Acute renal failure is a rare complication of Hepatitis A virus infection. Physicians should be aware of the potential renal involvement of Hepatitis A virus infection as the prognosis is not always favourable.
authors.affiliation: Department of Pediatrics, Medical College and Hospital, Kolkata, India. rbinod100@gmail.com
authors.forename: Radha B
authors.initials: RB
authors.lastname: Pal
authors.forename: Pritam
authors.initials: P
authors.lastname: Saha
authors.forename: Ira
authors.initials: I
authors.lastname: Das
authors.forename: Malay K
authors.initials: MK
authors.lastname: Sinha
mesh_terms: D002675:Child, Preschool; D003176:Complement C3 / Q000378:metabolism; D015432:Glomerulonephritis, Membranoproliferative / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006501:Hepatic Encephalopathy / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006506:Hepatitis A / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D017957:Hepatitis A Virus, Human / Q000302:isolation & purification; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D008099:Liver / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies
chemical_list: D003176:Complement C3; D007075:Immunoglobulin M