title: Is EQ-5D a valid quality of life instrument in patients with acute coronary syndrome?
abstract: OBJECTIVE
  To evaluate the construct validity of the Turkish version of the EQ-5D in patients with acute coronary syndrome.
  
  
  METHODS
  The study was conducted as a cross-sectional study at the Trakya University Hospital between February and May 2008. All patients completed the Turkish version of the EQ-5D and MacNew heart-related quality of life scale. Construct validity of the EQ-5D was assessed according to relationships with MacNew subscales by using Spearman rank correlation and multiple linear regression analyses.
  
  
  RESULTS
  One hundred and twenty-two patients responded to the instruments. Mean age was 62.9±9.3 years and male gender (88 or 72.1%) was dominant. Mean score of the EQ-5D index was 0.79±0.32, while the global score of MacNew was 5.01±1.16. The correlation coefficients of the EQ-5D index score with the MacNew subscales ranged from 0.557 to 0.721, with EQ-5D VAS score ranging from 0.297 to 0.484 (p<0.001 for all of them). According to the stepwise regression model MacNew global score was found to be significantly effective factor on EQ-5D index score (β =0.188; 95% CI: 0.152-0.224; p<0.001).
  
  
  CONCLUSIONS
  The Turkish version of the EQ-5D-based utility score seems to be a valid instrument in the assessment of quality of life studies in patients with acute coronary syndrome.
authors.affiliation: Department of Nursing, Health Sciences Institute, Faculty of Health Sciences, Trakya University, Edirne, Turkey. haticesut@yahoo.com
authors.forename: Hatice
authors.initials: H
authors.lastname: Kahyaoğlu Süt
authors.forename: Serap
authors.initials: S
authors.lastname: Unsar
mesh_terms: D054058:Acute Coronary Syndrome / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires / Q000592:standards*; D014421:Turkey