title: The utility of omega-3 fatty acids in epilepsy: more than just a farmed tilapia!
abstract: The epilepsies are one of the most common serious brain disorders and 20 to 30% of people developing epilepsy continue to have seizures and are refractory to treatment with the currently available therapies. Approximately one in a 1000 patients with chronic epilepsy will die suddenly, unexpectedly, and without explanation, even with post-mortem examination and this phenomenon is called sudden unexplained death in epilepsy (SUDEP). Understanding the mechanisms underlying SUDEP may lead to the identification of previously unrecognized risk factors that are more amenable to correction. We discuss here the possible implications of omega-3 fatty acids consumption on SUDEP prevention.
authors.affiliation: Centro de Cirurgia de Epilepsia, Departamento de Neurociências e Ciências do Comportamento, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, SP, Brazil.
authors.forename: Vera C
authors.initials: VC
authors.lastname: Terra
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Arida
authors.forename: Guilherme M
authors.initials: GM
authors.lastname: Rabello
authors.forename: Esper A
authors.initials: EA
authors.lastname: Cavalheiro
authors.forename: Fulvio A
authors.initials: FA
authors.lastname: Scorza
mesh_terms: D000818:Animals; D003645:Death, Sudden / Q000209:etiology / Q000517:prevention & control*; D004827:Epilepsy / Q000150:complications / Q000517:prevention & control*; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D005398:Fisheries; D006801:Humans; D051379:Mice; D018696:Neuroprotective Agents / Q000008:administration & dosage; D017210:Tilapia
chemical_list: D015525:Fatty Acids, Omega-3; D018696:Neuroprotective Agents