title: Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians.
abstract: This cross-sectional study aimed to estimate the prevalence of hyperuricemia and associated risk factors among Japanese-Brazilians. We obtained data on demographic, health history, food intake, and laboratory variables. Chi-square and prevalence ratios were used as measures of association. 35.3% of the subjects presented hyperuricemia, which was more frequent in smokers, males, age > 55 years, with co-morbidities, individuals on uric acid-increasing medication, serum creatinine > 1.4 mg/dL, high alcohol consumption, and low consumption of milk and dairy products. In the multivariate analysis, the associations remained significant with gender, overweight, central obesity, hypertriglyceridemia, and use of specific drugs. Among males, low intake of saturated fat was associated with hyperuricemia. Individuals with hypertension showed a negative association with dairy product consumption. The high hyperuricemia prevalence suggests that changes in nutritional profile and control of associated co-morbidities could help minimize occurrence of this condition.
authors.affiliation: Universidade Federal de São Paulo, Rua Osiris de Camargo 100, São Paulo, SP, Brazil. jupoletto@gmail.com
authors.forename: Juliana
authors.initials: J
authors.lastname: Poletto
authors.forename: Helena Aiko
authors.initials: HA
authors.lastname: Harima
authors.forename: Sandra Roberta Gouvea
authors.initials: SR
authors.lastname: Ferreira
authors.forename: Suely Godoy Agostinho
authors.initials: SG
authors.lastname: Gimeno
mesh_terms: D000328:Adult; D044466:Asian People / Q000706:statistics & numerical data*; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004032:Diet / Q000208:ethnology*; D004034:Diet Surveys; D005247:Feeding Behavior / Q000208:ethnology*; D005260:Female; D006801:Humans; D033461:Hyperuricemia / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology; D007564:Japan / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012959:Socioeconomic Factors