title: [Lung transplantation using donors 55 years and older].
abstract: OBJECTIVE
  We analyzed short, medium and long-term mortality in transplant recipients who received lungs from donors aged 55 years or more.
  
  
  METHODS
  All patients who underwent lung transplantation from donors aged 55 years or more were included. The association between the different study variables and early death and death at 1 year and 5 years was studied. A logistic regression model was used to study the association between early death and variables with a trend towards significance (P<.2) in the bivariate analysis. The risk factors for mortality at 1 year and 5 years were analyzed with a Cox regression model. The Kaplan-Meier method was used to analyze survival.
  
  
  RESULTS
  A total of 33 patients were included. The probability of survival was 90.9%, 78.5% and 44.8% at 1 month, 1 year, and 5 years after lung transplantation, respectively. The elevated age of the recipient (P=.16) and single-lung transplantation (P=.09) were the variables associated to or with a trend towards significant associations with mortality.
  
  
  CONCLUSIONS
  The final decision to accept a lung graft should be based on individual evaluation of each donor and recipient. However, given the lack of lung donors, donors aged 55 years or more should be considered for lung transplantation.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, España. eminambres@yahoo.es
authors.forename: E
authors.initials: E
authors.lastname: Miñambres
authors.forename: F
authors.initials: F
authors.lastname: Zurbano
authors.forename: S
authors.initials: S
authors.lastname: Naranjo
authors.forename: A
authors.initials: A
authors.lastname: González-Castro
authors.forename: R
authors.initials: R
authors.lastname: Mons
authors.forename: C
authors.initials: C
authors.lastname: González-Fernández
authors.forename: S
authors.initials: S
authors.lastname: Fernández-Rozas
authors.forename: M A
authors.initials: MA
authors.lastname: Ballesteros
mesh_terms: D000367:Age Factors; D001989:Bronchiolitis Obliterans / Q000401:mortality; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008168:Lung / Q000254:growth & development; D016040:Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000401:mortality; D009369:Neoplasms / Q000401:mortality; D055031:Primary Graft Dysfunction / Q000401:mortality; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D014019:Tissue Donors / Q000706:statistics & numerical data*; D009927:Tissue and Organ Procurement / Q000592:standards*