title: Successful double lung transplantation in a patient with bilateral pulmonary and sinus aspergillomas.
abstract: The outcome of patients with aspergilloma undergoing lung transplantation is not completely known, but anecdotal reports of poor outcome after transplant have discouraged this practice. We present a 45-year-old female with pulmonary sarcoidosis complicated by bilateral pulmonary and sinus aspergillomas who underwent successful double lung transplantation. Patients with aspergillomas can receive lung transplantation, provided that there is sufficient technical expertise to explant the infected lungs with minimal chance of chest wall contamination, and aggressive antifungal therapy is used post transplantation.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: L R
authors.initials: LR
authors.lastname: Minces
authors.forename: J K
authors.initials: JK
authors.lastname: Bhama
authors.forename: R
authors.initials: R
authors.lastname: Abdel-Massih
authors.forename: E J
authors.initials: EJ
authors.lastname: Kwak
authors.forename: S S
authors.initials: SS
authors.lastname: Haider
authors.forename: M H
authors.initials: MH
authors.lastname: Nguyen
authors.forename: Y
authors.initials: Y
authors.lastname: Toyoda
authors.forename: F P
authors.initials: FP
authors.lastname: Silveira
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D025141:Drug Resistance, Fungal; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008875:Middle Aged; D010254:Paranasal Sinus Diseases / Q000382:microbiology*; D055732:Pulmonary Aspergillosis / Q000188:drug therapy / Q000628:therapy*; D017565:Sarcoidosis, Pulmonary / Q000150:complications
chemical_list: D000935:Antifungal Agents