title: Dating the age of admixture via wavelet transform analysis of genome-wide data.
abstract: We describe a PCA-based genome scan approach to analyze genome-wide admixture structure, and introduce wavelet transform analysis as a method for estimating the time of admixture. We test the wavelet transform method with simulations and apply it to genome-wide SNP data from eight admixed human populations. The wavelet transform method offers better resolution than existing methods for dating admixture, and can be applied to either SNP or sequence data from humans or other species.
authors.affiliation: Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, D-04103, Germany. irina_pugach@eva.mpg.de.
authors.forename: Irina
authors.initials: I
authors.lastname: Pugach
authors.forename: Rostislav
authors.initials: R
authors.lastname: Matveyev
authors.forename: Andreas
authors.initials: A
authors.lastname: Wollstein
authors.forename: Manfred
authors.initials: M
authors.lastname: Kayser
authors.forename: Mark
authors.initials: M
authors.lastname: Stoneking
mesh_terms: D000465:Algorithms; D044383:Black People / Q000235:genetics; D005260:Female; D005367:Fiji; D005828:Genetics, Population / Q000379:methods* / Q000706:statistics & numerical data; D015894:Genome, Human; D055106:Genome-Wide Association Study; D023281:Genomics / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D058974:Phylogeography; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011114:Polynesia; D011157:Population Dynamics; D058067:Wavelet Analysis; D044465:White People / Q000235:genetics