title: Bacterial resistance and mortality in an intensive care unit.
abstract: The goal was to identify risk factors for healthcare-associated infections by resistant microorganisms and patient mortality in an Intensive Care Unit. A prospective and descriptive epidemiological research was conducted from 2005 till 2008, involving 2300 patients. Descriptive statistics, bivariate and multivariate logistic regression analysis were used. In bivariate analysis, infection caused by resistant microorganism was significantly associated to patients with community-acquired infection (p=0.03; OR=1.79) and colonization by resistant microorganism (p<0.01; OR=14.22). In multivariate analysis, clinical severity (p=0.03; OR=0.25) and colonization by resistant microorganism (p<0.01; OR=21.73) were significant. Mortality was associated to the following risk factors: type of patient, average severity index, besides mechanical ventilation. The relation between resistant microorganisms and death shows the need to monitor adherence to infection control measures so as to improve care quality and mainly survival of critical patients.
authors.affiliation: Escola de Enfermagem, Universidade Federal de Minas Gerais, MG, Brazil. adrianacoliveira@gmail.com
authors.forename: Adriana Cristina
authors.initials: AC
authors.lastname: de Oliveira
authors.forename: Rafael Souza
authors.initials: RS
authors.lastname: Silva
authors.forename: Mario E Piscoya
authors.initials: ME
authors.lastname: Díaz
authors.forename: Robert Aldo
authors.initials: RA
authors.lastname: Iquiapaza
mesh_terms: D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000453:epidemiology / Q000401:mortality*; D002648:Child; D003428:Cross Infection / Q000453:epidemiology / Q000401:mortality*; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D055815:Young Adult