title: In situ synthesis of thulium(III) hexacyanoferrate(II) nanoparticles and its application for glucose detection.
abstract: Thulium hexacyanoferrate (TmHCF) nanoparticles (NPs) were in situ synthesized within the chitosan film on the electrode surface by a biocatalyzed reaction. The properties of the obtained nanoparticles are characterized with scanning electron microscope (SEM) and energy-dispersive X-ray (EDX). The optimized conditions for the formation of TmHCF NPs were 16 mM Fe(CN)(6)(3-) and 1.5 mM Tm(3+) with an accumulation time of 20 min. Based on process of in situ synthesis of TmHCF NPs, a novel biosensor for glucose was designed, and there is a linear relationship between the current response of TmHCF NPs and glucose concentration. The linear range for glucose detection was 0.02-0.4 mM (r=0.9975, n=5) and 0.4-13.6 mM (r=0.9935, n=10) and the detection limit was 6 μM at a signal-to-noise ratio of 3.
authors.affiliation: Institute of Analytical Science, Shaanxi Provincial Key Labortary of Electroanalytical Chemistry, Northwest University, Taibai Road, Xi'an, Shaanxi 710069, China.
authors.forename: Zuchao
authors.initials: Z
authors.lastname: Meng
authors.forename: Jianbin
authors.initials: J
authors.lastname: Zheng
authors.forename: Qinglin
authors.initials: Q
authors.lastname: Sheng
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zheng
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D048271:Chitosan / Q000737:chemistry*; D004566:Electrodes; D005295:Ferrocyanides / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D013052:Spectrometry, X-Ray Emission; D013932:Thulium / Q000737:chemistry*
chemical_list: D005295:Ferrocyanides; C116383:ferrocyn; D013932:Thulium; D048271:Chitosan; D005947:Glucose