title: Feasibility of using cone-beam CT to verify and reposition the optically guided target localization of linear accelerator based stereotactic radiosurgery.
abstract: OBJECTIVE
  The optically guided target localization had been developed for linear accelerator based stereotactic radiosurgery (SRS). Unlike the traditional laser localization, the optical guided target localization utilizes a digital system to position patient. Although the system has been proven accurate and robust, it takes away the capability of physicist to directly double check the target position prior to irradiation. Any error from system calibration, data transformation, or head ring position maintenance will not be caught. The purpose of this work is to investigate the possibility of using cone-beam CT (CBCT) to double check the optically guided SRS target localization and reposition the patient.
  
  
  METHODS
  A SRS quality assurance (QA) phantom was used in the study. The phantom mounted with SRS head frame was scanned by computer tomography (CT) and planned according to the SRS radiation treatment planning process. A target isocenter is defined and transferred to the optically guided target localization system. The phantom was then transported to the linear accelerator room and localized at the initial position agreed by the optically guided target localization system and the CBCT system. Tests were conducted by moving/rotating the phantom to a set of preset offsets and taking CBCT images. Shifts detected by CBCT were compared with the preset offsets. Agreements between them were studied to see how well the CBCT was in discovering the optically guided target localization error.
  
  
  RESULTS
  Experiment results demonstrated good agreement between the CBCT detected phantom shift and the preset offset, when the offset is above 1 mm shift or 0.2 degree rotation. Offset less than 1 mm shift or 0.2 degree rotation was not detectable by CBCT.
  
  
  CONCLUSIONS
  The study concludes that the CBCT is able to discover the optically guided target localization error due to the system calibration or had ring migration. It is a valuable second check tool for SRS target localization quality assurance. The accuracy of CBCT in estimating patient positioning deviation satisfies the SRS procedures with generous tumor size and margin that can tolerate 1 mm or 0.2 degree accuracy. This avoids sending patient home without treatment. CBCT can be neither used as a primary SRS target localization nor can it be used to reposition the patient that cannot tolerate 1 mm shift or 0.2 degree rotation.
authors.affiliation: Cancer Care Department, Provena Saint Joseph Medical Center, Joliet, Illinois 60435, USA. jingeng.zhu@provena.org
authors.forename: Jingeng
authors.initials: J
authors.lastname: Zhu
mesh_terms: D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005240:Feasibility Studies; D007091:Image Processing, Computer-Assisted; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D016634:Radiosurgery / Q000295:instrumentation*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*