title: Sequential two-step multienzyme synthesis of tumor-associated sialyl T-antigens and derivatives.
abstract: A series of α2-3-sialylated β1-3-linked galactosides, including sialyl T-antigens, 3'-sialyl galacto-N-biose, 3'-sialyl lacto-N-biose, and their derivatives containing natural and non-natural sialic acid forms have been synthesized from simple monosaccharides using an efficient sequential two-step multienzyme approach.
authors.affiliation: Department of Chemistry, University of California, One Shields Avenue, Davis, California, USA.
authors.forename: Kam
authors.initials: K
authors.lastname: Lau
authors.forename: Hai
authors.initials: H
authors.lastname: Yu
authors.forename: Vireak
authors.initials: V
authors.lastname: Thon
authors.forename: Zahra
authors.initials: Z
authors.lastname: Khedri
authors.forename: Meghan E
authors.initials: ME
authors.lastname: Leon
authors.forename: Bao K
authors.initials: BK
authors.lastname: Tran
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
mesh_terms: D000951:Antigens, Neoplasm / Q000737:chemistry* / Q000378:metabolism; D001644:Bifidobacterium / Q000201:enzymology*; D005697:Galactosides / Q000737:chemistry; D005700:Galactosyltransferases / Q000378:metabolism*; D015394:Molecular Structure; D019158:N-Acetylneuraminic Acid / Q000737:chemistry*; D010325:Pasteurella / Q000201:enzymology*; D012799:Sialyltransferases / Q000378:metabolism*
chemical_list: D000951:Antigens, Neoplasm; D005697:Galactosides; D005700:Galactosyltransferases; C118176:beta-1,3-galactosyl-N-acetylhexosamine phosphorylase; D012799:Sialyltransferases; D019158:N-Acetylneuraminic Acid