title: Somatostatin reduces neuropeptide Y rise induced by physical exercise.
abstract: The effect of an i. v. infusion of somatostatin (SRIH) 4.1 μg/min×90 min on the basal secretion of NPY and on the NPY response to physical exercise was studied in normal men. Basal NPY secretion was not modified by SRIH infusion, whereas the NPY response to physical exercise was significantly lower in the presence of SRIH. These data suggest the involvement of a somatostatinergic mechanism in the regulation of NPY response to physical exercise.
authors.affiliation: Department of Internal Medicine and Biomedical Sciences, University of Parma, Italy. vittorio.coiro@unipr.it
authors.forename: V
authors.initials: V
authors.lastname: Coiro
authors.forename: R
authors.initials: R
authors.lastname: Volpi
authors.forename: S
authors.initials: S
authors.lastname: Cataldo
authors.forename: A
authors.initials: A
authors.lastname: Araldi
authors.forename: A
authors.initials: A
authors.lastname: Stella
authors.forename: G
authors.initials: G
authors.lastname: Saccani-Jotti
authors.forename: M L
authors.initials: ML
authors.lastname: Maffei
authors.forename: E
authors.initials: E
authors.lastname: Volta
authors.forename: P
authors.initials: P
authors.lastname: Chiodera
mesh_terms: D000328:Adult; D015536:Down-Regulation; D015444:Exercise; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009478:Neuropeptide Y / Q000097:blood*; D013004:Somatostatin / Q000008:administration & dosage / Q000378:metabolism*; D055815:Young Adult
chemical_list: D009478:Neuropeptide Y; D013004:Somatostatin