title: [Intratumoral versus subareolar injection in breast cancer sentinel lymph node biopsy. A case report].
abstract: The use of deep (intratumoral, peritumoral) and superficial (subdermal, subareolar) administration is recognized as valid in sentinel lymph node biopsy for breast cancer. Herein, we are presenting a clinical case in which a personalized methodology was a determining factor in axillary staging. Initially, the radiotracer was injected intratumorally guided by ultrasound. The ultrasound scan identified a previously unknown axillary lymphadenopathy, with focal cortical thickening, this being a non-specific ultrasound finding, but with possibility of biopsy. The lymphoscintigraphy did not show uptake in the mentioned node, hence, a second subareolar dose was administered. On this occasion, the lymphoscintigraphy detected drainage to the sentinel node, which was the only one positive for micrometastases.
authors.affiliation: Servicio de Medicina Nuclear, Complejo Asistencial de Burgos, Burgos, Spain. ilanchas@cyl.com
authors.forename: I
authors.initials: I
authors.lastname: Lanchas Alfonso
authors.forename: M B
authors.initials: MB
authors.lastname: Miguel Martínez
authors.forename: J F
authors.initials: JF
authors.lastname: CuezvaGuzmán
authors.forename: P
authors.initials: P
authors.lastname: Rupérez Arribas
authors.forename: S
authors.initials: S
authors.lastname: Martínez Blanco
authors.forename: J M
authors.initials: JM
authors.lastname: Yartu San Millán
authors.forename: J J
authors.initials: JJ
authors.lastname: Duque Gallo
mesh_terms: D001365:Axilla; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D009367:Neoplasm Staging; D009558:Nipples; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage*
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid