title: Neuroscience of behavioral and pharmacological treatments for addictions.
abstract: Although substantial advances have been made in behavioral and pharmacological treatments for addictions, moving treatment development to the next stage may require novel ways of approaching addictions, particularly ways based on new findings regarding the neurobiological underpinnings of addictions that also assimilate and incorporate relevant information from earlier approaches. In this review, we first briefly review theoretical and biological models of addiction and then describe existing behavioral and pharmacologic therapies for the addictions within this framework. We then propose new directions for treatment development and targets that are informed by recent evidence regarding the heterogeneity of addictions and the neurobiological contributions to these disorders.
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA. marc.potenza@yale.edu
authors.forename: Marc N
authors.initials: MN
authors.lastname: Potenza
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sofuoglu
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Carroll
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Rounsaville
mesh_terms: D000818:Animals; D001521:Behavior Therapy / Q000379:methods*; D004358:Drug Therapy / Q000379:methods*; D006801:Humans; D009488:Neurosciences; D012054:Reinforcement, Psychology; D019966:Substance-Related Disorders / Q000188:drug therapy* / Q000523:psychology / Q000534:rehabilitation*