title: Habitual intake of guaraná and metabolic morbidities: an epidemiological study of an elderly Amazonian population.
abstract: The aim of the present study was to evaluate the associations of metabolic disorders and anthropometric and biochemical biomarkers of lipid, glucose and oxidative metabolism and the habitual ingestion of guaraná (Paullinia cupana, Mart. Var. sorbilis) by an elderly population residing in the Amazon Riverine region of the Maués municipality (Brazil). A case-controlled study was performed that included 637 elderly (≥60 years of age) patients classified as either those who habitually drank guaraná (GI, n = 421) or those who never drank guaraná (NG, n = 239) based upon their self-reported intake of guaraná. Indeed, the prevalence of various metabolic disorders was associated with guaraná ingestion. The prevalence of hypertension, obesity and metabolic syndrome in the GI group was lower than the prevalence found in the NG group. The NG group exhibited lower systolic and diastolic blood pressure values. The males in the GI group exhibited a lower waist circumference, on average, than the circumference found in the NG group, whereas the females in the GI group had lower cholesterol (total and LDL-c) levels than the control cohort. Additionally, a significant association was found between lower levels of advanced oxidative protein product (AOPP) and habitual guaraná consumption. The results constitute the first epidemiological study to suggest a potentially protective effect of habitual guaraná ingestion against metabolic disorders in elderly subjects.
authors.affiliation: Departamento de Morfologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Brazil; Programa de Pós-Graduação em Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil.
authors.forename: Cristina da Costa
authors.initials: Cda C
authors.lastname: Krewer
authors.forename: Euler Esteves
authors.initials: EE
authors.lastname: Ribeiro
authors.forename: Ednéa Aguiar Maia
authors.initials: EA
authors.lastname: Ribeiro
authors.forename: Rafael Noal
authors.initials: RN
authors.lastname: Moresco
authors.forename: Maria Izabel de Ugalde Marques
authors.initials: MI
authors.lastname: da Rocha
authors.forename: Greice Franciele Feyl dos Santos
authors.initials: GF
authors.lastname: Montagner
authors.forename: Michel Mansur
authors.initials: MM
authors.lastname: Machado
authors.forename: Karin
authors.initials: K
authors.lastname: Viegas
authors.forename: Elorídes
authors.initials: E
authors.lastname: Brito
authors.forename: Ivana Beatrice Mânica
authors.initials: IB
authors.lastname: da Cruz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001628:Beverages; D001794:Blood Pressure; D001938:Brazil / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D008659:Metabolic Diseases / Q000453:epidemiology*; D024821:Metabolic Syndrome / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D010084:Oxidation-Reduction; D032126:Paullinia; D055105:Waist Circumference
chemical_list: D002784:Cholesterol