title: Activation of caspase protease during apoptosis in ovarian cancer cells.
abstract: As a genetically controlled program, apoptosis has important roles in a variety of biological processes. The realization that chemotherapy can also induce apoptosis in some cancer cells both in vitro and in vivo indicates apoptosis may play a very important role in cancer and cancer therapy (1,2). Many of the molecules that participate in the apoptotic cell suicide have been identified. At the heart of this pathway are a family of cysteine proteases, the "caspases" (3).
authors.affiliation: Laboratory of Biomedical Research, Institute of Molecular and Cellular Bioscience, University of Tokyo, Tokyo, Japan.
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: M
authors.initials: M
authors.lastname: Naito
authors.forename: T
authors.initials: T
authors.lastname: Mashima
authors.forename: S
authors.initials: S
authors.lastname: Hiroyuki
authors.forename: T
authors.initials: T
authors.lastname: Tsuruo