title: Preterm infants fed nutrient-enriched formula until 6 months show improved growth and development.
abstract: BACKGROUND
  The purpose of the present study was to determine the effect of feeding nutrient-enriched preterm formula to preterm infants until 6 months' corrected age (CA) on growth and development in the first 18 months of life.
  
  
  METHODS
  Very low-birthweight preterm infants were fed preterm formula until term (40 weeks CA). Infants were then assigned to one of three groups and were fed term formula until 6 months' CA (group 1, n= 29); preterm formula to 3 months' CA and then term formula to 6 months' CA (group 2, n= 30); or preterm formula until 6 months' CA (group 3, n= 31). Anthropometry was performed at term, 3, 6, 9, 12, 15, and at s18 months' CA. Mental and psychomotor development were assessed using the Bayley Scales of Infant Development II at 18 months' CA.
  
  
  RESULTS
  Although body weight, length, head circumference and z score for CA at term in group 3 were significantly lower than those of groups 1 and 2, growth rates of these parameters were significantly higher in group 3 up to 18 months CA', as compared to groups 1 and 2. The mental developmental index and psychomotor developmental index of the Bayley test were not significantly different between the three groups.
  
  
  CONCLUSIONS
  Very low-birthweight preterm infants fed nutrient-enriched preterm formula until 6 months' CA demonstrated significantly improved growth rates for bodyweight, length and head circumference, and comparable mental and psychomotor development throughout the first 18 months of life.
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Ga Won
authors.initials: GW
authors.lastname: Jeon
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Yu Jin
authors.initials: YJ
authors.lastname: Jung
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Koh
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Yeon Kyung
authors.initials: YK
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Kyung Ah
authors.initials: KA
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Son Moon
authors.initials: SM
authors.lastname: Shin
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Sung Shin
authors.initials: SS
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Jae Won
authors.initials: JW
authors.lastname: Shim
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Yun Sil
authors.initials: YS
authors.lastname: Chang
authors.affiliation: Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, BusanDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Pediatrics, Cheil General Hospital, Kwandong University College of MedicineDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, SeoulDepartment of Pediatrics, Bucheon Hospital, Soonchunhyang University, College of Medicine, Bucheon, Korea.
authors.forename: Won Soon
authors.initials: WS
authors.lastname: Park
mesh_terms: D002657:Child Development; D019587:Dietary Supplements; D006128:Growth; D006801:Humans; D041943:Infant Formula / Q000737:chemistry*; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight