title: Post-traumatic stress disorders, mood disorders, and quality of life in transplant recipients with acute liver failure.
abstract: OBJECTIVE
  The objective of this study was to assess post-traumatic stress disorder (PTSD), depression, anxiety, and quality of life among acute hepatitis patients undergoing liver transplantation.
  
  
  METHODS
  Twenty-four patients underwent transplantation due to acute liver failure. After a brief anamnestic interview to gather demographic and clinical information, each participant underwent a psychological assessment using the SF-36 Health Survey (SF-36), Impact of Events Scale-Revised (IES-R), Hospital Anxiety and Depression (HAD) Scale, as well as Beck Depression Inventory (BDI).
  
  
  RESULTS
  The average age of the patients was 41.17 years (±17.03); the mean time after transplantation was 13.50 ± 13.80 months; 83% of the subjects were women. Anxiety symptoms were observed in 33.2% of the participants and depression in 16.7% by HAD and 45.8% by BDI. By IES-R 46.2% of patients presented high to severe levels of stress. The majority of participants (54.2%) showed good quality of life scores. A correlation analysis indicated a significant negative association between SF-36 score and other scales (from -0.514 to -0.681). Upon a comparative analysis, a significant difference between groups was only noted in SF-36 score (P = .032).
  
  
  CONCLUSIONS
  The results led us to conclude that anxiety, depression, and PTSD were negatively associated with quality of life in this population. These symptoms also contributed directly to determine well-being among these patients.
authors.affiliation: Psychology Service and the Transplantation Unit of the Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil. melissasg@einstein.br
authors.forename: M S
authors.initials: MS
authors.lastname: Guimaro
authors.forename: S S
authors.initials: SS
authors.lastname: Lacerda
authors.forename: M R
authors.initials: MR
authors.lastname: Aguilar
authors.forename: C H
authors.initials: CH
authors.lastname: Karam
authors.forename: A M
authors.initials: AM
authors.lastname: Kernkraut
authors.forename: B H
authors.initials: BH
authors.lastname: Ferraz-Neto
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017114:Liver Failure, Acute / Q000150:complications / Q000523:psychology* / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications*; D011788:Quality of Life; D013313:Stress Disorders, Post-Traumatic / Q000150:complications*