title: Intravenous thrombolytic treatment in a patient with transient ischemic attack associated with mural carotid thrombi.
abstract: A 77-year old man experiencing frequent transient ischemic attacks for five days was admitted to our hospital. Radiological examinations including brain computed tomography, supraaortic computed tomography angiography were performed. Supraaortic computed tomography angiography revealed two thrombi in common carotid artery. Thrombi were located proximally, one of which was elongated and adhared to the arterial wall and the other one was located below bifurcation of left carotid artery. Since the case has been categorized as a high risk patient for ischemic stroke despite the normal neurological status, intravenous recombinant tissue plasminogen activator was given. Ischemic attacks completely ceased soon after thrombolysis. Control computed tomography angiography revealed normal findings with patent carotid artery, without any clot. To our knowledge this is the only case of transient ischemic attack treated with intravenous recombinant tissue plasminogen activator in the literature with the score of 0 on the National Institutes of Health Stroke Scale.
authors.affiliation: Dokuz Eylül University, Faculty of Medicine, Department of Neurology, İzmir, Turkey. erdem.yaka@deu.edu.tr
authors.forename: Erdem
authors.initials: E
authors.lastname: Yaka
authors.forename: Süleyman
authors.initials: S
authors.lastname: Men
authors.forename: Vesile
authors.initials: V
authors.lastname: Öztürk
authors.forename: Kürşad
authors.initials: K
authors.lastname: Kutluk
mesh_terms: D000368:Aged; D002339:Carotid Arteries / Q000473:pathology; D002341:Carotid Artery Thrombosis / Q000150:complications* / Q000188:drug therapy*; D002533:Cerebral Angiography; D004562:Electrocardiography; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator