title: Genomics for disease treatment and prevention.
abstract: The enormous advances in genetics and genomics of the past decade have the potential to revolutionize health care, including mental health care, and bring about a system predominantly characterized by the practice of genomic and personalized medicine. This article briefly reviews the history of genetics and genomics and assesses the extent to which the results of genetic and genomic studies are currently being leveraged clinically for disease treatment and prevention. Relevant social, economic, and policy issues relevant to genomic medicine are also reviewed, and priority research areas in which further work is needed are identified.
authors.affiliation: The Scripps Translational Science Institute, 3344 North Torrey Pines Court, La Jolla, CA 92037, USA.
authors.forename: Cinnamon S
authors.initials: CS
authors.lastname: Bloss
authors.forename: Dilip V
authors.initials: DV
authors.lastname: Jeste
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Schork
mesh_terms: D055808:Drug Discovery / Q000191:economics / Q000379:methods; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000379:methods; D055106:Genome-Wide Association Study / Q000379:methods; D023281:Genomics / Q000379:methods*; D006291:Health Policy / Q000331:legislation & jurisprudence; D006801:Humans; D001523:Mental Disorders / Q000235:genetics / Q000517:prevention & control* / Q000628:therapy*; D008605:Mental Health Services; D057285:Precision Medicine / Q000191:economics / Q000379:methods*; D011322:Primary Prevention / Q000379:methods