title: Reflections on involuntary treatment in the prevention of fatal anorexia nervosa: a review of five cases.
abstract: OBJECTIVE
  Involuntary treatment in the prevention of fatal anorexia nervosa (AN) is still controversial.
  
  
  METHODS
  Five fatal cases of AN were identified out of 1,160 patients who attended a specialized eating disorder unit between 1994 and 2006. Information on inpatient, ambulatory, and emergency room treatment was extracted from a population-based registration system.
  
  
  RESULTS
  Personality disorders were diagnosed in all five patients and substance abuse in three patients. In all cases, illness duration was more than 10 years and late onset was seen in two cases. None of the deaths were due to suicide. Involuntary hospital admission was instituted for three patients, but only one patient was compulsory detained more than once. Four patients died after having discontinued treatment.
  
  
  CONCLUSIONS
  Compulsory treatment may be of crucial importance in the prevention of fatalities in patients with long-standing AN and psychiatric comorbidity who discontinue treatment.
authors.affiliation: Department of Endocrinology, Center for Eating Disorders, Odense University Hospital, Denmark.
authors.forename: Janni Schmidt
authors.initials: JS
authors.lastname: Holm
authors.forename: Kim
authors.initials: K
authors.lastname: Brixen
authors.forename: Alin
authors.initials: A
authors.lastname: Andries
authors.forename: Kirsten
authors.initials: K
authors.lastname: Hørder
authors.forename: Rene Klinkby
authors.initials: RK
authors.lastname: Støving
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000523:psychology* / Q000628:therapy; D017809:Fatal Outcome; D006760:Hospitalization; D006801:Humans; D007297:Inpatients; D013405:Suicide / Q000523:psychology*; D016312:Treatment Refusal