title: Impact of endosulfan on certain hematological and biochemical parameters of catfish Labeo fimbriatus: sublethal study.
abstract: Hematological and biochemical parameters are routinely used as indicators of the physiological or sublethal stress response to endogenous or exogenous changes in fish. In this work, the sublethal toxic effects of endosulfan (0.002 mg l⁻¹) on certain hematological and biochemical parameters of Labeo fimbriatus were examined for 28 days and the analyses were made on 7, 14, 21, and 28 days. Endosulfan caused significant lower value of red blood corpuscles (RBC), hemoglobin, plasma glucose, and protein levels when compared to the control groups (p < 0.05). However, white blood corpuscles (WBC) increased throughout the study period. The results indicate that a low amount of endosulfan alters the hematological and biochemical parameters of fish, which can be useful in diagnosing the structural and functional status of fish exposed to toxicants.
authors.affiliation: Unit of Toxicology, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, Tamil Nadu, India.
authors.forename: Manoharan
authors.initials: M
authors.lastname: Saravanan
authors.lastname: Alora Echuliath Vidhya
authors.forename: Mathan
authors.initials: M
authors.lastname: Ramesh
authors.forename: Annamalai
authors.initials: A
authors.lastname: Malarvizhi
authors.forename: Chokkalingam
authors.initials: C
authors.lastname: Kavitha
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis; D002397:Catfishes / Q000502:physiology*; D004726:Endosulfan / Q000633:toxicity*; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000187:drug effects*; D006454:Hemoglobins / Q000032:analysis / Q000187:drug effects*; D007962:Leukocytes / Q000187:drug effects*; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D006454:Hemoglobins; D014874:Water Pollutants, Chemical; D004726:Endosulfan