title: [Microbiological profile of infections in the Intensive Care Units of Colombia (EPISEPSIS Colombia].
abstract: OBJECTIVE
  Valid and reliable data regarding sepsis is lacking in Colombia. Our aim was to determine the prevalence of the microorganisms in the main infections treated in Intensive Care Units (ICUs) in our country.
  
  
  METHODS
  This is a sub-study of a prospective cohort with 10 general hospitals in Colombia during a 6-month period. The inclusion criteria were hospitalization in ICU and confirmation of infection according to the CDC definitions. Patients were classified into three groups, that is, community, hospital and intensive care, according to the site where the infection was acquired.
  
  
  RESULTS
  A total of 826 patients were included in this analysis. Of these, 51% developed infections in the community, 5.33% in the hospital and 43.7% in intensive care unit. Overall, the most common diagnoses were pneumonia (29.54%), intra-abdominal infection (18.16%) and urinary tract infection (11.62%). The most frequent germ in community-acquired infections was E. coli -lung (16. 4%), peritoneum (57.7%), urine (55.5%), blood (22.4%)-. E. coli -peritoneum (29.3%), urine (52.9%)- also predominated in the ICU-acquired infections, except for lung and blood in which Staphylococcus aureus (32.4%) and Klebsiella pneumoniae (15.7%) were the most prevalent. Cultures were requested from 655 patients, 40% of them having received antibiotics before cultures were taken, although this did not affected the percentages of positive cultures (P=0.583).
  
  
  CONCLUSIONS
  Pneumonia was the main cause of infection regardless of the site of acquisition. E. coli was the most prevalent germ, except in the pulmonary infections acquired in UCI in which S. aureus was the most prevalent.
authors.affiliation: Unidad de Terapia Intensiva, Clínica Universitaria Bolivariana, Medellín, Departamento de Antioquia, Colombia. sofipacho@hotmail.com
authors.forename: F J
authors.initials: FJ
authors.lastname: Molina
authors.forename: C A
authors.initials: CA
authors.lastname: Díaz
authors.forename: L
authors.initials: L
authors.lastname: Barrera
authors.forename: G
authors.initials: G
authors.lastname: De La Rosa
authors.forename: R
authors.initials: R
authors.lastname: Dennis
authors.forename: C
authors.initials: C
authors.lastname: Dueñas
authors.forename: M
authors.initials: M
authors.lastname: Granados
authors.forename: D
authors.initials: D
authors.lastname: Londoño
authors.forename: G
authors.initials: G
authors.lastname: Ortiz
authors.forename: F
authors.initials: F
authors.lastname: Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Jaimes
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D001431:Bacteriological Techniques; D003105:Colombia / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D004927:Escherichia coli Infections / Q000453:epidemiology; D006769:Hospitals, General / Q000706:statistics & numerical data; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007710:Klebsiella Infections / Q000453:epidemiology; D010538:Peritonitis / Q000453:epidemiology / Q000382:microbiology; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000382:microbiology; D011446:Prospective Studies; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents