title: [Acute dyspnea in malignant melanoma].
abstract: Metastases to the larynx are rare. The current article presents the case of a 75-year-old patient with a history of shortness of breath due to a supraglottic exophytic lesion that was identified as a metastasis of a cutaneous melanoma treated 2.5 years previously. As a result of our medline analysis we found approximately 30 cases of metastatic melanoma to the larynx published to date. Primary tumors are always cutaneous in origin and spread over the whole integument of trunk and extremities. The time interval between diagnosis of the primary and the laryngeal metastasis is often several years. In most reports a supraglottic exophytic, red coloured lesion is described. Diagnosis can only be proven by histological examination. Laryngeal metastasis is usually an indication of tumor dissemination and always has a fatal prognosis.
authors.affiliation: Klinik für HNO-Krankheiten und plastische Operationen, Ruppiner Kliniken GmbH, Fehrbelliner Straße 38, 16816, Neuruppin, Deutschland. a.franzen@ruppiner-kliniken.de
authors.forename: A M
authors.initials: AM
authors.lastname: Franzen
authors.forename: T
authors.initials: T
authors.lastname: Günzel
mesh_terms: D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology*; D005931:Glottis / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D007828:Laryngoscopy; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D009361:Neoplasm Invasiveness; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed