title: Spin-spin coupling edition in chiral liquid crystal NMR solvent.
abstract: The application of the G-SERFph pulse sequence is presented on enantiomeric mixtures dissolved in a chiral liquid crystal. It aims at editing, within one single 2D spectrum, every proton coupling which is experienced by a given proton site in the molecule, and leads to real phased T-edited spectroscopy (T=J+2D). This NMR experiment is based on the combination of homonuclear semi-selective refocusing techniques with a spatial frequency encoding of the sample. This approach, which consists in handling selectively each coupling in separate cross sections of the sample, is applied to the visualization of enantiomers dissolved in a chiral liquid crystalline phase. Advantages and limits of this methodology are widely discussed.
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 CNRS Univ Paris-Sud 11, bât 410, 91405 Orsay cedex, France.
authors.forename: Denis
authors.initials: D
authors.lastname: Merlet
authors.forename: Laetitia
authors.initials: L
authors.lastname: Béguin
authors.forename: Jacques
authors.initials: J
authors.lastname: Courtieu
authors.forename: Nicolas
authors.initials: N
authors.lastname: Giraud
mesh_terms: D016477:Artifacts; D002138:Calibration; D003080:Cold Temperature; D004852:Epoxy Compounds / Q000737:chemistry; D050866:Liquid Crystals / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D011522:Protons; D012997:Solvents; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D011522:Protons; D012997:Solvents; C009068:propylene oxide