title: Mouse models for cancer research.
abstract: Mouse models of cancer enable researchers to learn about tumor biology in complicated and dynamic physiological systems. Since the development of gene targeting in mice, cancer biologists have been among the most frequent users of transgenic mouse models, which have dramatically increased knowledge about how cancers form and grow. The Chinese Journal of Cancer will publish a series of papers reporting the use of mouse models in studying genetic events in cancer cases. This editorial is an overview of the development and applications of mouse models of cancer and directs the reader to upcoming papers describing the use of these models to be published in coming issues, beginning with three articles in the current issue.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Lynette
authors.initials: L
authors.lastname: Moore
authors.forename: Ping
authors.initials: P
authors.lastname: Ji
mesh_terms: D000818:Animals; D001354:Avian Leukosis Virus / Q000235:genetics; D030161:Avian Proteins / Q000235:genetics* / Q000378:metabolism; D004195:Disease Models, Animal; D018390:Gene Targeting; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009362:Neoplasm Metastasis; D009374:Neoplasms, Experimental / Q000235:genetics* / Q000378:metabolism; D034622:RNA Interference; D011991:Receptors, Virus / Q000235:genetics* / Q000378:metabolism
chemical_list: D030161:Avian Proteins; D011991:Receptors, Virus; C088745:Tva receptor