title: Screening for antimicrobial resistance genes and virulence factors via genome sequencing.
abstract: Second-generation genome sequencing and alignment of the resulting reads to in silico genomes containing antimicrobial resistance and virulence factor genes were used to screen for undesirable genes in 28 strains which could be used in human nutrition. No virulence factor genes were detected, while several isolates contained antimicrobial resistance genes.
authors.affiliation: Innovation, Chr. Hansen A/S, 10-12 Bøge Allé, DK-2970 Hørsholm, Denmark.
authors.forename: Mads
authors.initials: M
authors.lastname: Bennedsen
authors.forename: Birgitte
authors.initials: B
authors.lastname: Stuer-Lauridsen
authors.forename: Morten
authors.initials: M
authors.lastname: Danielsen
authors.forename: Eric
authors.initials: E
authors.lastname: Johansen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D001644:Bifidobacterium / Q000187:drug effects / Q000235:genetics; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D016680:Genome, Bacterial; D007778:Lactobacillus / Q000187:drug effects / Q000235:genetics; D013294:Lactococcus lactis / Q000187:drug effects / Q000235:genetics; D008826:Microbial Sensitivity Tests / Q000379:methods*; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA / Q000379:methods*; D013291:Streptococcus / Q000187:drug effects / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D037521:Virulence Factors