title: Can anti-erosion dentifrices also provide effective plaque control?
abstract: OBJECTIVE
  While gingivitis and caries continue to be prevalent issues, there is growing concern about dental erosion induced by dietary acids. An oral hygiene product that protects against all these conditions would be beneficial. This study investigated the potential of two anti-erosion dentifrices to inhibit plaque.
  
  
  METHODS
  This was a randomized, three-period, two-treatment, double-blind, crossover study evaluating a stannous chloride/sodium fluoride dentifrice (SnCl(2)/NaF, blend-a-med(®) Pro Expert) and a popular anti-erosion dentifrice (NaF, Sensodyne(®) ProNamel(™)). During Period 3, subjects were randomized to repeat one treatment to evaluate any product carryover effects. Each treatment period was 17 days. Test dentifrices were used with a standard manual toothbrush. Digital plaque image analysis (DPIA) was employed at the end of each period to evaluate plaque levels (i) overnight (am prebrush); (ii) post-brushing with the test product (am post-brush); and (iii) mid-afternoon (pm). Analysis was conducted via an objective computer algorithm, which calculated total area of visible plaque.
  
  
  RESULTS
  Twenty-seven subjects completed the study. At all time points, subjects had statistically significantly (P ≤ 0.0001) lower plaque levels after using the SnCl(2)/NaF dentifrice than the NaF dentifrice. The antiplaque benefit for the SnCl(2)/NaF dentifrice versus the NaF dentifrice was: am prebrush = 26.0%; am post-brushing = 27.9%; pm = 25.7%.
  
  
  CONCLUSIONS
  The SnCl(2)/NaF dentifrice provided significantly greater daytime and overnight plaque inhibition than the NaF toothpaste. When recommending dentifrice to patients susceptible to dental erosion, clinicians can consider one that also inhibits plaque.
authors.affiliation: Procter & Gamble, London Innovation Centre, Egham, Surrey, UK. bellamy.pg@pg.com
authors.forename: P G
authors.initials: PG
authors.lastname: Bellamy
authors.forename: M
authors.initials: M
authors.lastname: Prendergast
authors.forename: R
authors.initials: R
authors.lastname: Strand
authors.forename: Z
authors.initials: Z
authors.lastname: Yu
authors.forename: T N
authors.initials: TN
authors.lastname: Day
authors.forename: M L
authors.initials: ML
authors.lastname: Barker
authors.forename: A J
authors.initials: AJ
authors.lastname: Mussett
mesh_terms: D000328:Adult; D000465:Algorithms; D018592:Cross-Over Studies; D003481:Cuspid / Q000473:pathology; D003773:Dental Plaque / Q000473:pathology / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D019793:Fluorescein; D005456:Fluorescent Dyes; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007180:Incisor / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012969:Sodium Fluoride / Q000627:therapeutic use; D014002:Tin Fluorides / Q000627:therapeutic use; D014077:Tooth Erosion / Q000517:prevention & control*; D014099:Toothbrushing / Q000295:instrumentation
chemical_list: D003802:Dentifrices; D005456:Fluorescent Dyes; D014002:Tin Fluorides; D012969:Sodium Fluoride; D019793:Fluorescein