title: [Efficient, minimally invasive periodontal therapy. An evidence based treatment concept].
abstract: A large number of reports indicate beneficial effects of systemic antibiotics for patients with periodontal diseases. Although these advantages are clear in general, the specific relationship of benefit and risk in various clinical situations remains a subject of debate. Uncertainties persist regarding the individual prescription and combination with other procedures. Since the early 1990s it has been pointed out that systemic antibiotics given in the context of non-surgical subgingival debridement may reduce the need for periodontal surgery. Recent studies confirm these findings especially with regard to the combination of amoxicillin and metronidazole. However, these antibiotics should not be viewed as a substitute for thorough debridement, or as a means to compensate for improper oral hygiene. In addition, current evidence does not provide evidence for the indiscriminate use of just any antibiotic in any periodontal patient. A treatment protocol implementing the recent evidence is shown. It is noteworthy to realize that chronic and aggressive periodontitis today can be treated successfully with simple and cost-effective means in most instances.
authors.affiliation: Division de Physiopathologie buccale et Parodontie Section de Médecine Dentaire, Université de Genève, Suisse.
authors.forename: Andrea
authors.initials: A
authors.lastname: Mombelli
authors.forename: Fabien
authors.initials: F
authors.lastname: Décaillet
authors.forename: Adnan
authors.initials: A
authors.lastname: Almaghlouth
authors.forename: Philipp
authors.initials: P
authors.lastname: Wick
authors.forename: Norbert
authors.initials: N
authors.lastname: Cionca
mesh_terms: D000284:Administration, Oral; D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000187:drug effects; D010520:Aggressive Periodontitis / Q000188:drug therapy / Q000628:therapy; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D055113:Chronic Periodontitis / Q000188:drug therapy / Q000628:therapy*; D003362:Cost-Benefit Analysis; D012534:Dental Scaling; D004311:Double-Blind Method; D055094:Evidence-Based Dentistry; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D057747:Periodontal Debridement; D016966:Porphyromonas gingivalis / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D000658:Amoxicillin