title: Side effects assessment in glicolyc acid peelings in patients with acne type I.
abstract: Chemical peeling implies the application of a chemical agent to the skin, which causes controlled destruction of a part or the entire epidermis, with or without the dermis, leading to exfoliation and removal of superficial lesions, followed by regeneration of new epidermal and dermal tissues. The present study was directed toward safety concerns associated with superficial chemical peeling with glycolic acid (GA) in different concentrations at patients with acne tip I. A sample of 90 patients of either sex, aged between 17 to 21 years, were included in the study and submitted to superficial chemical peeling for acne vulgaris. The study lasted eight weeks and peeling sessions were carried out in each patient. Tolerance to the procedure and any undesirable effects noted during these sessions were recorded. For data statistical analysis and interpretation of results, software program "SPSS version 13" was used. Results were expressed through the descriptive statistics, as simple frequencies and percentages, while for establishing of statistically significant differences, in use was Friedman's test of significance. Almost all the patients tolerated the procedure well. Of totally 90 patients, only six, at the end of therapy experienced hard erythema, only ten, at the end of therapy experienced hard desquamation and only eleven, at the end of therapy experienced hard sensation of pulling of facial skin. Chemical peeling with glycolic acid is a well tolerated and safe treatment modality in acne type I.
authors.affiliation: Health Centre in Niš, St. Vojvode Tankosića, Niš, Serbia. sanjaperic67@gmail.com
authors.forename: Sanja
authors.initials: S
authors.lastname: Perić
authors.forename: Maja
authors.initials: M
authors.lastname: Bubanj
authors.forename: Saša
authors.initials: S
authors.lastname: Bubanj
authors.forename: Snežana
authors.initials: S
authors.lastname: Jančić
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D002615:Chemexfoliation / Q000009:adverse effects / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006016:Glycolates / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007641:Keratolytic Agents / Q000009:adverse effects / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006016:Glycolates; D007641:Keratolytic Agents; C031149:glycolic acid