title: The domestic dog: man's best friend in the genomic era.
abstract: The domestic dog genome--shaped by domestication, adaptation to human-dominated environments and artificial selection--encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.
authors.affiliation: Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305-5120, USA. aboyko@stanford.edu
authors.forename: Adam R
authors.initials: AR
authors.lastname: Boyko
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000235:genetics*; D001947:Breeding; D002874:Chromosome Mapping; D004285:Dogs / Q000235:genetics*; D014644:Genetic Variation; D016678:Genome; D055106:Genome-Wide Association Study; D023281:Genomics / Q000379:methods*; D005838:Genotype; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D010641:Phenotype; D010802:Phylogeny; D058974:Phylogeography; D020641:Polymorphism, Single Nucleotide; D019655:Quantitative Trait, Heritable; D012641:Selection, Genetic