title: [Cognitive deterioration after cardiosurgery].
abstract: Over 100,000 heart surgeries are performed in Germany annually. Although severe neurological complications like ischaemic strokes have meanwhile become rare occurrences, subtle neuropsychological changes are still frequently recognized after major heart surgeries. The hitherto unsolved problem of postoperative cognitive decline (POCD) is portrayed in this article. Multifactorial aetiologies including microembolism and preoperative risk factors are supposed to play a significant role in POCD. A variety of neuroprotective strategies such as intraoperative microemboli filtration have been suggested to minimize cerebral risks. The utility of neuroprotective methods has recently been verified in randomized studies.
authors.affiliation: Abteilung für Neurologie, Justus-Liebig-Universität Giessen, Giessen, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Schwarz
authors.forename: M
authors.initials: M
authors.lastname: Schönburg
authors.forename: S
authors.initials: S
authors.lastname: Kastaun
authors.forename: T
authors.initials: T
authors.lastname: Gerriets
authors.forename: M
authors.initials: M
authors.lastname: Kaps
mesh_terms: D002545:Brain Ischemia / Q000453:epidemiology* / Q000517:prevention & control*; D013504:Cardiovascular Surgical Procedures / Q000706:statistics & numerical data*; D003072:Cognition Disorders / Q000453:epidemiology* / Q000517:prevention & control*; D015897:Comorbidity; D005858:Germany / Q000453:epidemiology; D006801:Humans; D018696:Neuroprotective Agents / Q000627:therapeutic use; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control*; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D018696:Neuroprotective Agents