title: Standing guard at the mucosa.
abstract: Most successful vaccines elicit antibodies that protect against infection. In this issue of Immunity, Bomsel et al. (2011) show in the rhesus macaque model that vaccine-induced mucosal antibodies, rather than circulating neutralizing antibodies, may be critical components for protective immunity against HIV-1.
authors.affiliation: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle, WA 98109, USA.
authors.forename: M Juliana
authors.initials: MJ
authors.lastname: McElrath