title: Potent anti-platelet constituents from Centaurea iberica.
abstract: New naturally occurring nitrogenous compounds 1 and 2, along with a new dimeric lignan glucoside 3, have been isolated from the ethyl acetate soluble fraction of Centaurea iberica. Their structures have been elucidated through spectroscopic techniques. All the isolated compounds showed significant platelet aggregation inhibition.
authors.affiliation: International Centre for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan. abdul.malik@iccs.edu.
authors.forename: Amna Nisar
authors.initials: AN
authors.lastname: Khan
authors.forename: Itrat
authors.initials: I
authors.lastname: Fatima
authors.forename: Urooj Abdul
authors.initials: UA
authors.lastname: Khaliq
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Ghulam Abbas
authors.initials: GA
authors.lastname: Miana
authors.forename: Zia-Ur-Rehman
authors.initials: ZU
authors.lastname: Qureshi
authors.forename: Huma
authors.initials: H
authors.lastname: Rasheed
mesh_terms: D031179:Centaurea / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010975:Platelet Aggregation Inhibitors