title: Is tumor growth faster with obstructive colonic cancer?
abstract: BACKGROUND
  It is generally known that long duration of untreated colonic cancer can lead to obstruction. Another contributing factor might be tumor growth rate. The present study was conducted to compare tumor growth rates related to lymph node metastasis of the obstructive and non-obstructive colonic cancers.
  
  
  METHODS
  169 patients who underwent operations for colonic cancer were studied retrospectively. Patient and tumor characteristics as well as clinical outcomes were analyzed.
  
  
  RESULTS
  94 patients (55.6%) presented with obstructed colonic cancers, and 75 (44.4%) with non-obstructed, 78.7% and 57.3%, respectively having a tumor size greater than 5 cm. On logistic regression analysis, both groups had similar lymph node metastasis rates (OR=1.6; 95% CI=0.8-3.2).
  
  
  CONCLUSIONS
  No relations between obstruction and tumour size or lymph node metastasis were found. Thus, obstructions only occur because of other factors and do not contribute to tumor growth. Utilizing effective screening programs to determine obstructions is recommended.
authors.affiliation: General Surgical Unit, Department of Surgery, Chonburi Hospital, Chonburi, Thailand. surawutch@gmail.com
authors.forename: Surawut
authors.initials: S
authors.lastname: Charoenkajonchai
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000473:pathology*; D007902:Length of Stay; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult