title: Chemotherapy in epithelial ovarian cancer.
abstract: Epithelial ovarian cancer is the most common type of ovarian cancer; usually occurs in women older than 50years, and because 75% of cases are diagnosed at stage III or IV it is associated with a poor prognosis. Treatment of ovarian cancer is based on the integration of surgery and chemotherapy. Chemotherapy plays a major role both in the adjuvant treatment and in the care of patients with advanced disease. Several active drugs have been introduced in the treatment of ovarian cancer in the last decades and novel targets and agents are under evaluation.
authors.affiliation: Division of Medical Oncology, Department of Urology and Gynecology, National Cancer Institute of Naples, Via Mariano Semmola, 80131 Naples, Italy. sandro.pignata@gmail.com
authors.forename: Sandro
authors.initials: S
authors.lastname: Pignata
authors.forename: Lucia
authors.initials: L
authors.lastname: Cannella
authors.forename: Davide
authors.initials: D
authors.lastname: Leopardo
authors.forename: Carmela
authors.initials: C
authors.lastname: Pisano
authors.forename: Giovanni Salvatore
authors.initials: GS
authors.lastname: Bruni
authors.forename: Gaetano
authors.initials: G
authors.lastname: Facchini
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004358:Drug Therapy / Q000379:methods; D005260:Female; D006801:Humans; D008495:Medical Oncology / Q000379:methods; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D011379:Prognosis; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents