title: Skew deviation after intratympanic gentamicin therapy.
abstract: Intratympanic gentamicin therapy for the treatment of episodic vertigo associated with Ménière's disease is generally well tolerated. Although auditory and vestibular symptoms following intratympanic gentamicin are well known, visual disturbance has not been previously described. In this report, we describe two patients with Ménière's disease who developed sudden onset of binocular vertical diplopia due to skew deviation after intratympanic gentamicin therapy. The skew deviation and diplopia resolved spontaneously and completely within 6 to 8 weeks without therapy. Development of diplopia due to skew deviation should be discussed as a potential complication in patients undergoing intratympanic gentamicin therapy.
authors.affiliation: Department of Ophthalmology, New York University School of Medicine, New York, New York, USA.
authors.forename: Diana
authors.initials: D
authors.lastname: Ng
authors.forename: Mohammad
authors.initials: M
authors.lastname: Fouladvand
authors.forename: Anil K
authors.initials: AK
authors.lastname: Lalwani
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004172:Diplopia / Q000139:chemically induced*; D004432:Ear, Middle / Q000187:drug effects; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007267:Injections; D008297:Male; D008575:Meniere Disease / Q000188:drug therapy*; D008875:Middle Aged; D012075:Remission, Spontaneous; D019233:Retreatment; D013285:Strabismus / Q000139:chemically induced*
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins