title: Vitamin D, immunoregulation, and rheumatoid arthritis.
abstract: In addition to being important in calcium and phosphorus metabolism, bone formation, and mineralization, vitamin D also plays a part in the maintenance of immune homeostasis. Vitamin D receptors are expressed in a number of different tissues, including, and perhaps most notably, on immune cells. The presence or absence of activated vitamin D has a number of effects on in vitro immune cell function. This review describes the possible immunoregulatory role of vitamin D in rheumatoid arthritis with clinical and animal studies.
authors.affiliation: Shanxi Medical University, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China. wenhongyan0509@yahoo.cn
authors.forename: Hongyan
authors.initials: H
authors.lastname: Wen
authors.forename: Joshua F
authors.initials: JF
authors.lastname: Baker
mesh_terms: D000818:Animals; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000503:physiopathology*; D019587:Dietary Supplements; D004195:Disease Models, Animal; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D007107:Immune System / Q000502:physiology*; D016896:Treatment Outcome; D014807:Vitamin D / Q000008:administration & dosage / Q000502:physiology* / Q000627:therapeutic use
chemical_list: D018501:Antirheumatic Agents; D014807:Vitamin D