title: Helical chiral 2,2'-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane.
abstract: A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2'-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylation of N-acylhydrazones.
authors.affiliation: Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, Florida 33146-0431, United States.
authors.forename: Jinshui
authors.initials: J
authors.lastname: Chen
authors.forename: Burjor
authors.initials: B
authors.lastname: Captain
authors.forename: Norito
authors.initials: N
authors.lastname: Takenaka
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*; D010293:Pargyline / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D010087:Oxides; D012821:Silanes; D015082:2,2'-Dipyridyl; D010293:Pargyline