title: [Correlation of powder properties and formability of traditional Chinese medicine pellets].
abstract: OBJECTIVE
  To investigate the correlation of powder properties and formability of traditional Chinese medicine pellets prepared by extrusion/spheronization.
  
  
  METHODS
  The present effort was designed to evaluate the effects of the characters of powder on pellets formation by extrusion-spheronization, taking Danggui Buxue decoction extracts as a model drug and microcrystalline cellulose (MCC) as an ideal balling material for extrusion-spheronization.
  
  
  RESULTS
  The diameter of powder had correlation with the plane critical angle of pellets in a certain scope and the sticky coefficient of wet mass affected roundness of pellets.
  
  
  CONCLUSIONS
  Properties of powder have influence on formability of traditional Chinese medicine pellets.
authors.affiliation: Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. shoujiao.student@sina.com
authors.forename: Yang
authors.initials: Y
authors.lastname: Huang
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Jia
authors.forename: Jing
authors.initials: J
authors.lastname: Zhu
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Hongxia
authors.initials: H
authors.lastname: Chen
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
mesh_terms: D002626:Chemistry, Pharmaceutical; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry*; D010316:Particle Size; D011208:Powders / Q000008:administration & dosage / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D011208:Powders