title: Magneto-photo-acoustic imaging.
abstract: Magneto-photo-acoustic imaging, a technique based on the synergy of magneto-motive ultrasound, photoacoustic and ultrasound imaging, is introduced. Hybrid nanoconstructs, liposomes encapsulating gold nanorods and iron oxide nanoparticles, were used as a dual-contrast agent for magneto-photo-acoustic imaging. Tissue-mimicking phantom and macrophage cells embedded in ex vivo porcine tissue were used to demonstrate that magneto-photo-acoustic imaging is capable of visualizing the location of cells or tissues labeled with dual-contrast nanoparticles with sufficient contrast, excellent contrast resolution and high spatial resolution in the context of the anatomical structure of the surrounding tissues. Therefore, magneto-photo-acoustic imaging is capable of identifying the nanoparticle-labeled pathological regions from the normal tissue, providing a promising platform to noninvasively diagnose and characterize pathologies.
authors.forename: Min
authors.initials: M
authors.lastname: Qu
authors.forename: Srivalleesha
authors.initials: S
authors.lastname: Mallidi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mehrmohammadi
authors.forename: Ryan
authors.initials: R
authors.lastname: Truby
authors.forename: Kimberly
authors.initials: K
authors.lastname: Homan
authors.forename: Pratixa
authors.initials: P
authors.lastname: Joshi
authors.forename: Yun-Sheng
authors.initials: YS
authors.lastname: Chen
authors.forename: Konstantin
authors.initials: K
authors.lastname: Sokolov
authors.forename: Stanislav
authors.initials: S
authors.lastname: Emelianov