title: [In vitro anti-influenza virus activity of 10 traditional Chinese medicines].
abstract: Influenza virus is a virus causing upper respiratory tract infection disease with high morbidity and mortality. China is considered as an area with high rate of influenza morbidity. Prevention and treatment of influenza currently rely on vaccines and antiviral agents in the world. In addition, traditional Chinese medicines also have been used in clinical for influenza therapy. In vitro anti-influenza virus activities of 10 traditional Chinese medicines were studied by cytopathic effect (CPE). Qingre Jiedu oral liquid (factory H) had strong antiviral activity against influenza virus A/Guangdong Luohu/219/2006 (H1N1); Yinhuang oral liquid had strong antiviral activity against influenza virus A/Hanfang/359/95 and A/Yuefang/243/72 (H3N2). Qingkailing oral liquid (factory G) had strong antiviral activity against influenza virus A/Jifang/15/90 (H3N2). Qingre Jiedu oral liquid (factory H) had strong antiviral activity against influenza virus A/Jifang/15/90, A/Yuefang/243/72 (H3N2) and virus B.
authors.affiliation: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
authors.forename: Wei-ying
authors.initials: WY
authors.lastname: He
authors.forename: Rong-mei
authors.initials: RM
authors.lastname: Gao
authors.forename: Xing-qiong
authors.initials: XQ
authors.lastname: Li
authors.forename: Jian-dong
authors.initials: JD
authors.lastname: Jiang
authors.forename: Yu-huan
authors.initials: YH
authors.lastname: Li
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage / Q000494:pharmacology*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000008:administration & dosage / Q000494:pharmacology; D002460:Cell Line; D002726:Chlorogenic Acid / Q000008:administration & dosage / Q000494:pharmacology; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects*; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology; D007211:Indoles / Q000008:administration & dosage / Q000494:pharmacology; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects*; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects*; D009981:Influenza B virus / Q000187:drug effects; D039823:Iridoids / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D007211:Indoles; D039823:Iridoids; C504928:Qingkailing; C550187:Qingrejiedu; D002726:Chlorogenic Acid