title: Cognitive deterioration and duration of untreated psychosis.
abstract: OBJECTIVE
  To examine the relationship between cognitive deterioration and the duration of untreated psychosis (DUP) in a first-episode psychosis sample.
  
  
  METHODS
  We assessed a consecutive sample of first-episode psychosis participants (N = 50) with measures of cognitive deterioration and DUP.
  
  
  RESULTS
  Using correlations and stepwise linear regressions, we found strong relationships between DUP and measures of cognitive deterioration.
  
  
  CONCLUSIONS
  The length of DUP predicted cognitive deterioration. These results highlight a potential DUP grace period (>6 months) in which significant cognitive deterioration may be averted.
authors.affiliation: School of Psychology, University College Dublin, Dublin, Ireland. keith.gaynor@gmail.com
authors.forename: Keith
authors.initials: K
authors.lastname: Gaynor
authors.forename: Barbara
authors.initials: B
authors.lastname: Dooley
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Lawlor
authors.forename: L Richard
authors.initials: LR
authors.lastname: Lawoyin
authors.forename: Eadbhard
authors.initials: E
authors.lastname: O'Callaghan
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D057210:Delayed Diagnosis; D018450:Disease Progression; D005260:Female; D006801:Humans; D007494:Ireland; D008297:Male; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000523:psychology*; D013997:Time Factors; D014888:Wechsler Scales