title: Structural characterization and mechanical performance of calcium phosphate scaffolds and natural bones: a comparative study.
abstract: OBJECTIVE
  The knowledge of the mechanical response of bones and their substitutes is pertinent to numerous medical problems. Understanding the effects of mechanical influence on the body is the first step toward developing innovative treatment and rehabilitation concepts for orthopedic disorders.
  
  
  METHODS
  This was a comparative study of 5 synthetic scaffolds based on porous calcium phosphates and natural bones, with regard to their microstructural, chemical, and mechanical characterizations. The structural and chemical characterizations of the scaffolds were examined by means of X-ray diffraction, scanning electron microscopy, and X-ray spectroscopy analysis. The mechanical characterization of bones and bone graft biomaterials was carried out through compression tests using samples with noncomplex geometry.
  
  
  RESULTS
  Analysis of the chemical composition, surface features, porosity, and compressive strength indicates that hydroxyapatite-based materials and trabecular bone have similar properties.
authors.affiliation: Foundation Tekniker - IK4, Gipuzkoa, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Fuentes
authors.forename: Virginia
authors.initials: V
authors.lastname: Sáenz de Viteri
authors.forename: Amaya
authors.initials: A
authors.lastname: Igartua
authors.forename: Roberta
authors.initials: R
authors.lastname: Martinetti
authors.forename: Laura
authors.initials: L
authors.lastname: Dolcini
authors.forename: Gotzone
authors.initials: G
authors.lastname: Barandika
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength; D008855:Microscopy, Electron, Scanning; D016062:Porosity; D013499:Surface Properties; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates