title: [Prognostic value of normal myocardial perfusion scintigraphy with 201Tl in post-acute myocardial infarction].
abstract: OBJECTIVE
  The purpose of this work has been to determine the prognostic value of normal thallium-201 myocardial perfusion scintigraphy (MPS) in patients who had suffered myocardial infarction in the three months prior to the examination.
  
  
  METHODS
  A stress test followed by (201)Tl Gated SPECT was performed. A follow-up was made of 63 patients with normal perfusion scintigraphy. According to the MPS results, the patients were divided into 2 groups. Group I (n=63; 57% males, age 65±12), patients with normal MPS, and group II (n=60; 81% males, age 64±10), patients with abnormal MPS. The appearance of a new infarction or cardiac death occurring during this period (63±3 months) was analyzed. The appearance of events was related with the cardiovascular risk factors, perfusion study and ventricular function.
  
  
  RESULTS
  Five events occurred in group I in 4 patients: 3 new infarctions and 2 cardiac deaths. In group II, there were 18 events in 14 patients: 8 new infarctions and 10 cardiac deaths (p<0,0001). The events were related with age, time from MPS, diabetes, size of perfusion defect and post stress ventricular ejection fraction. Mean survival en group I was 108 months (103-112) and in group II 97 (88-107) (p=0,01).
  
  
  CONCLUSIONS
  Patients with normal MPS had fewer major events than patients with abnormal MPS. The size of MPS has been related with the appearance of events. A depressed post-stress left ventricular ejection fraction has a poor prognosis.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Carlos III, Madrid, Spain. fgonzalez.hciii@salud.madrid.org
authors.forename: F G
authors.initials: FG
authors.lastname: Gallardo
authors.forename: M V
authors.initials: MV
authors.lastname: Gómez
authors.forename: I
authors.initials: I
authors.lastname: Terol
mesh_terms: D000368:Aged; D015897:Comorbidity; D048909:Diabetes Complications / Q000000981:diagnostic imaging / Q000401:mortality; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D015637:Gated Blood-Pool Imaging; D006321:Heart / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006973:Hypertension / Q000150:complications; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000000981:diagnostic imaging* / Q000401:mortality / Q000473:pathology; D055414:Myocardial Perfusion Imaging; D009765:Obesity / Q000150:complications; D011379:Prognosis; D019275:Radiopharmaceuticals; D012008:Recurrence; D012189:Retrospective Studies; D012907:Smoking; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon; D018754:Ventricular Dysfunction / Q000000981:diagnostic imaging / Q000209:etiology
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes