title: Lewis acid-mediated Michaelis-Arbuzov reaction at room temperature: a facile preparation of arylmethyl/heteroarylmethyl phosphonates.
abstract: A facile preparation of arylmethyl and heteroarylmethyl phosphonate esters was achieved involving a Lewis acid mediated Michaelis-Arbuzov reaction at room temperature. Interaction of arylmethyl halides/alcohols with triethyl phosphite in the presence of Lewis acid at room temperature afforded phosphonate esters in good yields.
authors.affiliation: Department of Organic Chemistry, School of Chemistry, University of Madras, Guindy Campus Chennai 600 025, Tamil Nadu, India.
authors.forename: Ganesan Gobi
authors.initials: GG
authors.lastname: Rajeshwaran
authors.forename: Meganathan
authors.initials: M
authors.lastname: Nandakumar
authors.forename: Radhakrishnan
authors.initials: R
authors.lastname: Sureshbabu
authors.forename: Arasambattu K
authors.initials: AK
authors.lastname: Mohanakrishnan
mesh_terms: D004952:Esters; D058116:Lewis Acids / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
chemical_list: D004952:Esters; D058116:Lewis Acids; D063065:Organophosphonates