title: [The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
abstract: OBJECTIVE
  In this study, the efficacy of preemptive dexketoprofen usage on postoperative pain relief and tramadol consumption was evaluated.
  
  
  METHODS
  Fifty American Society of Anesthesiologists (ASA)-I or ASA-II patients undergoing plastic surgery were randomized into two groups. Group 1 received dexketoprofen 25 mg and Group 2 received placebo tablets 1 hour (h) before surgery. All patients received a standard anesthetic protocol. At the end of the surgery, all patients received intravenous tramadol with Patient Controlled Analgesia (PCA) device. Pain scores was evaluated with visual analog scale during the postoperative 1st, 8th and 24th h. Tramadol consumption, adverse effects and patient satisfaction were recorded.
  
  
  RESULTS
  The pain scores and tramadol consumption were significantly lower in Group 1 (p<0.05). Nausea and vomiting were observed more in Group 2 than Group 1, and patient satisfaction was better in Group 1 (p<0.05).
  
  
  CONCLUSIONS
  Preemptive use of dexketoprofen reduced postoperative tramadol consumption and incidence of adverse events.
authors.affiliation: Konya Training and Research Hospital, Konya, Turkey. drincikara@yahoo.com
authors.forename: Inci
authors.initials: I
authors.lastname: Kara
authors.forename: Sema
authors.initials: S
authors.lastname: Tuncer
authors.forename: Atilla
authors.initials: A
authors.lastname: Erol
authors.forename: Ruhiye
authors.initials: R
authors.lastname: Reisli
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007660:Ketoprofen / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control*; D011229:Preanesthetic Medication; D019651:Plastic Surgery Procedures; D014147:Tramadol / Q000008:administration & dosage*; D014325:Tromethamine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D014147:Tramadol; D007660:Ketoprofen; C118296:dexketoprofen trometamol