title: [CT coronary angiography combined with adenosine stress myocardial perfusion scintigraphy for detecting flow-limiting coronary stenoses].
abstract: OBJECTIVE
  To assess the feasibility and accuracy of CT coronary angiography (CTCA) combined with adenosine stress myocardial perfusion scintigraphy (MPS) for diagnosis of flow-limiting coronary stenosis.
  
  
  METHODS
  A total of 105 patients with suspected or established coronary artery disease (CAD) underwent CTCA and MPS within 4 weeks before invasive coronary angiography. The accuracy of CTCA/MPS in the diagnosis of flow-limiting coronary stenosis was evaluated in comparison with the results of quantitative coronary angiography and MPS.
  
  
  RESULTS
  The sensitivity, specificity, positive predictive value and negative predictive value of CTCA/MPS as a combined approach for detection of flow-limiting coronary stenosis were all 100%. In 16% (9/55) of the patients, revascularization procedures were performed and no flow-limiting stenosis was found.
  
  
  CONCLUSIONS
  Combination of CTCA and MPS has an excellent accuracy for detecting flow-limiting coronary stenosis as compared with quantitative coronary angiography/MPI, and can be a useful gatekeeper for revascularization procedures.
authors.affiliation: Department of Cardiology, General Hospital of PLA, Beijing 100853, China. doctorwq@126.com
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Qin
authors.forename: Zhi-guo
authors.initials: ZG
authors.lastname: Wang
authors.forename: Zhi-wei
authors.initials: ZW
authors.lastname: Guan
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
authors.forename: Zhi-jun
authors.initials: ZJ
authors.lastname: Sun
authors.forename: Lu-yue
authors.initials: LY
authors.lastname: Gai
authors.forename: Yun-dai
authors.initials: YD
authors.lastname: Chen
authors.forename: Jia-He
authors.initials: JH
authors.lastname: Tian
authors.forename: Li
authors.initials: L
authors.lastname: Yang
mesh_terms: D000241:Adenosine; D000368:Aged; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed
chemical_list: D000241:Adenosine