title: Combination of photodynamic therapy and immunomodulation for skin diseases--update of clinical aspects.
abstract: In dermatology, photodynamic therapy (PDT) has become a well established treatment modality which has been shown to be effective and safe for many skin and mucosal disorders. Pre-clinical and clinical studies demonstrate that, in addition to the direct local cytotoxicity and vascular effects, PDT can induce various host immune responses. Recent clinical data also show that improved clinical outcomes can be obtained through the sequential use of PDT and immunomodulation. This article will provide an update on the current status of such a combination in dermatological applications.
authors.affiliation: PDT Center, Shanghai Skin Diseases and STD Hospital, Shanghai, P R China.
authors.forename: Xiu-Li
authors.initials: XL
authors.lastname: Wang
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Wang
authors.forename: Kai-Hua
authors.initials: KH
authors.lastname: Yuan
authors.forename: Fu-Lun
authors.initials: FL
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D010778:Photochemotherapy; D012871:Skin Diseases / Q000188:drug therapy* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism
chemical_list: D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents