title: Synthesis of biphenyl-2-carbonitrile derivatives via a palladium-catalyzed sp2 C-H bond activation using cyano as a directing group.
abstract: Pd(II)-catalyzed aromatic C-H bond activation using cyano as a directing group was carried out in TFA medium. Biphenyl-2-carbonitrile derivatives were therefore synthesized from aryl nitriles and aryl halides in moderate to good yields.
authors.affiliation: Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210097, China.
authors.forename: Wu
authors.initials: W
authors.lastname: Li
authors.forename: Zhipeng
authors.initials: Z
authors.lastname: Xu
authors.forename: Peipei
authors.initials: P
authors.lastname: Sun
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Jiang
authors.forename: Min
authors.initials: M
authors.lastname: Fang
mesh_terms: D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006847:Hydrocarbons, Iodinated / Q000737:chemistry; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001713:Biphenyl Compounds; D006847:Hydrocarbons, Iodinated; D009570:Nitriles; D010165:Palladium; C010574:biphenyl