title: [Dynamic extraction process of salvianolic acids].
abstract: OBJECTIVE
  To optimize the dynamic extraction process of salvianolic acids.
  
  
  METHODS
  Salvianolic acids was selected as index. The effects of extraction temperature, granularity, solvent multiple, circle value and extraction time were studied on the process of dynamical extraction. The orthogonal experiment was employed to investigate the influence of different parameters.
  
  
  RESULTS
  The optimal extracting method of salvianolic acids was as follows: temperature was 80 degrees C, granularity was 4 mm, circle value was 30 L x h(-1), solvent multiple was 10 times and extraction time was 150 min.
  
  
  CONCLUSIONS
  By comparison to static extraction, dynamic extraction can improve the extraction efficiency, reduce the solvent and energy consumption, as well as lower the burden of post-processing.
authors.affiliation: Engineering Center for Traditional Chinese Medicine Modernization, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
authors.forename: Lingqiao
authors.initials: L
authors.lastname: Lu
authors.forename: Yongchuan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Xian
authors.initials: X
authors.lastname: Chen
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Jieting
authors.initials: J
authors.lastname: Dai
mesh_terms: D001572:Benzofurans / Q000032:analysis / Q000302:isolation & purification*; D005591:Chemical Fractionation / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000302:isolation & purification*; D013696:Temperature; D053630:Depsides
chemical_list: D001572:Benzofurans; D004365:Drugs, Chinese Herbal; C076944:salvianolic acid B; D053630:Depsides