title: Vertebroplasty for symptomatic monostotic Paget disease.
abstract: Paget disease (PD) is a chronic metabolically active bone disorder. The spine is the second most commonly involved site; the pathologic changes can cause back pain, myeloradiculopathy, and vertebral fracture. Symptomatic patients are treated medically, and surgery is required when certain complications occur. A case is presented of monostotic vertebral PD treated by percutaneous vertebroplasty (PV) with successful outcome characterized by pain relief and improved disability at 6-month follow-up. PV is proposed as a primary treatment for back pain secondary to PD when unresponsive to conservative therapy and when not associated with other complications.
authors.affiliation: Department of Bioimaging and Radiological Sciences, Catholic University of Rome, A.Gemelli Hospital-L go Vito 1, 00168 Rome, Italy. apedicelli@rm.unicatt.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pedicelli
authors.forename: Fabio
authors.initials: F
authors.lastname: Papacci
authors.forename: Antonio
authors.initials: A
authors.lastname: Leone
authors.forename: Celestino
authors.initials: C
authors.lastname: De Simone
authors.forename: Costantino
authors.initials: C
authors.lastname: De Simone
authors.forename: Mario
authors.initials: M
authors.lastname: Meglio
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Bonomo
authors.forename: Cesare
authors.initials: C
authors.lastname: Colosimo
mesh_terms: D001416:Back Pain / Q000209:etiology / Q000601:surgery; D001706:Biopsy; D001843:Bone Cements / Q000627:therapeutic use; D004185:Disability Evaluation; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D010147:Pain Measurement; D019904:Polymethyl Methacrylate / Q000627:therapeutic use; D049268:Positron-Emission Tomography; D015641:Radiography, Interventional; D013131:Spine / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D054854:Vertebroplasty
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate