title: A comparison of stem cells for therapeutic use.
abstract: A critical comparison of the attributes of several types of stem cells is presented, with particular emphasis on properties that are critical for the application of these cells for therapeutic purposes. The importance of an autologous source of pluripotent stem cells is stressed. It is apparent that two sources currently exist for non-embryonic pluripotent stem cells--very small embryonic-like stem cells (VSELs) and induced pluripotent stem cells (iPS). The impact of the emerging iPS research on therapy is considered.
authors.affiliation: NeoStem, Inc., 420 Lexington Avenue, Suite 450, New York, NY 10170, USA. drodgerson@neostem.com
authors.forename: Denis O
authors.initials: DO
authors.lastname: Rodgerson
authors.forename: Alan G
authors.initials: AG
authors.lastname: Harris
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D002465:Cell Movement; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000502:physiology; D044127:Epigenesis, Genetic; D005819:Genetic Markers; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000502:physiology; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000502:physiology / Q000637:transplantation; D051379:Mice; D012038:Regeneration; D057905:Stem Cell Research; D033581:Stem Cell Transplantation
chemical_list: D005819:Genetic Markers