title: 3-D FDTD simulation of shear waves for evaluation of complex modulus imaging.
abstract: The Navier equation describing shear wave propagation in 3-D viscoelastic media is solved numerically with a finite differences time domain (FDTD) method. Solutions are formed in terms of transverse scatterer velocity waves and then verified via comparison to measured wave fields in heterogeneous hydrogel phantoms. The numerical algorithm is used as a tool to study the effects on complex shear modulus estimation from wave propagation in heterogeneous viscoelastic media. We used an algebraic Helmholtz inversion (AHI) technique to solve for the complex shear modulus from simulated and experimental velocity data acquired in 2-D and 3-D. Although 3-D velocity estimates are required in general, there are object geometries for which 2-D inversions provide accurate estimations of the material properties. Through simulations and experiments, we explored artifacts generated in elastic and dynamic-viscous shear modulus images related to the shear wavelength and average viscosity.
authors.affiliation: Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, Urbana, IL, USA. moresca2@illinois.edu
authors.forename: Marko
authors.initials: M
authors.lastname: Orescanin
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Michael
authors.initials: M
authors.lastname: Insana
mesh_terms: D000465:Algorithms; D016477:Artifacts; D003198:Computer Simulation; D055119:Elastic Modulus; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D019047:Phantoms, Imaging; D014463:Ultrasonography / Q000379:methods*; D014783:Viscosity
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate