title: Cardiac safety of the electroconvulsive therapy-paliperidone combination: a preliminary study.
abstract: Both electroconvulsive therapy (ECT) and paliperidone (PLP) can induce, though infrequently, severe cardiac side-effects. Thus far, no studies are available on the cardiac safety of their co-administration. We report on the cardiac safety of the ECT-PLP combination in nine female inpatients who underwent this treatment modality. In a total of 83 ECT patient sessions, the ECT-PLP combination was well tolerated. No patient exhibited any noticeable prolongation of QTc interval and no adverse cardiac events, in particular arrhythmias, were noted.
authors.affiliation: 1st Department of Psychiatry, Eginition Hospital, Athens University Medical School, 11528 Athens, Greece. vmasdrakis@med.uoa.gr
authors.forename: Vasilios G
authors.initials: VG
authors.lastname: Masdrakis
authors.forename: George
authors.initials: G
authors.lastname: Tzanoulinos
authors.forename: Maria
authors.initials: M
authors.lastname: Markatou
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Oulis
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control*; D003131:Combined Modality Therapy; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000627:therapeutic use*; D000068882:Paliperidone Palmitate; D011743:Pyrimidines / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D007555:Isoxazoles; D011743:Pyrimidines; D000068882:Paliperidone Palmitate