title: Gliomatosis cerebri: a possible clinical and neuroradiologic "stroke mimic".
abstract: BACKGROUND
  Thrombolytic therapy for acute ischemic stroke is based on clinical assessment, blood tests, and computed tomography (CT) findings. The presence of early CT ischemic changes may help support therapeutic decision. Our aim is to call attention to a likely overlooked "stroke mimic," Gliomatosis Cerebri (GC).
  
  
  METHODS
  Clinical and neuroimaging analysis of 3 patients with documented GC, whose acute clinical onset and CT data (lenticular and ribbon sign and a ipsilateral dot sign) were suggestive of ischemic stroke.
  
  
  CONCLUSIONS
  Noncerebrovascular conditions may present with both acute onset and false CT signs of early ischemic stroke. Although rare, GC needs to be considered among the possible "stroke mimics" to avoid inappropriate thrombolytic therapy.
authors.affiliation: Neuroradiologic Unit, University Hospital of Padua, Padua, Italy.
authors.forename: Renzo
authors.initials: R
authors.lastname: Manara
authors.forename: Rita
authors.initials: R
authors.lastname: Marasco
authors.forename: Valentina
authors.initials: V
authors.lastname: Citton
authors.forename: Milena
authors.initials: M
authors.lastname: Calderone
authors.forename: Sandro Dal
authors.initials: SD
authors.lastname: Pos
authors.forename: Chiara
authors.initials: C
authors.lastname: Briani
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis* / Q000473:pathology; D020521:Stroke / Q000175:diagnosis* / Q000188:drug therapy; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed / Q000379:methods*