title: High-relaxivity MRI contrast agents prepared from miniemulsion polymerization using gadolinium(III)-based metallosurfactants.
abstract: Miniemulsion polymerization with amphiphilic gadolinium(III) complexes as metallosurfactants was explored as a new technique for the synthesis of high relaxivity MRI contrast agents. Well-defined metallo-colloids with up to 240% enhancement in relaxivity over their small molecular counterparts were obtained.
authors.affiliation: Key Lab for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Rd, Shanghai, 200237, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Gong
authors.forename: Zhengyan
authors.initials: Z
authors.lastname: Chen
authors.forename: Yingying
authors.initials: Y
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Wang
authors.forename: Aiguo
authors.initials: A
authors.lastname: Hu
mesh_terms: D003287:Contrast Media / Q000737:chemistry*; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry; D004655:Emulsions / Q000737:chemistry; D005682:Gadolinium / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D049329:Nanostructures / Q000737:chemistry; D058105:Polymerization; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D056831:Coordination Complexes; D004655:Emulsions; D013501:Surface-Active Agents; D005682:Gadolinium