title: Investigation on the aggregation behaviors of DDAB/NaDEHP catanionic vesicles in the absence and presence of a negatively charged polyelectrolyte.
abstract: The aggregation behaviors of the cationic and anionic (catanionic) surfactant vesicles formed by didodecyldimethylammonium bromide (DDAB)/sodium bis(2-ethylhexyl) phosphate (NaDEHP) in the absence and presence of a negatively charged polyelectrolyte are investigated. The amount of the charge on the vesicle can be tuned by controlling the DDAB/NaDEHP surfactant molar ratio. The charged vesicular dispersions made of DDAB/NaDEHP are mixed with a negatively charged polyelectrolyte, poly(4-styrenesulfonic acid-co-maleic acid) sodium (PSSAMA), to form complexes. Depending on the polyelectrolyte/vesicle charge ratio, complex flocculation or precipitation occurs. Characterization of the catanionic vesicles and the complexes are performed by transmission electron microscope (TEM), Cryo-TEM, dynamic light scattering (DLS), conductivity, turbidity, zeta potential, isothermal titration calorimetry (ITC) and small-angle X-ray scattering (SAXS) measurements.
authors.affiliation: School of Pharmaceutical Science, Shandong University, Jinan, Shandong Province, P R China.
authors.forename: Feifei
authors.initials: F
authors.lastname: Li
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Luan
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Liu
authors.forename: Guiying
authors.initials: G
authors.lastname: Xu
authors.forename: Xiuhong
authors.initials: X
authors.lastname: Li
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D002412:Cations; D008298:Maleates / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D008954:Models, Biological; D015394:Molecular Structure; D010316:Particle Size; D011137:Polystyrenes / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D002412:Cations; D008298:Maleates; D011137:Polystyrenes; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; C518261:poly(4-styrenesulfonic acid-co-maleic acid); C046112:didodecyldimethylammonium