title: [Clinical evaluation of large periapical lesions following apical surgery].
abstract: OBJECTIVE
  To evaluate the therapeutic effect of teeth with large periapical lesions followed apical surgery.
  
  
  METHODS
  59 patients (59 periapical lesions, 91 teeth) with large periapical lesions ranging in size from 6 mm to 21 mm in diameter were included in this study. All teeth were treated by root canal therapy and apical surgery, and the surgical procedure was completed with microsurgical technology and ultrasonic root-end preparation. The outcomes were evaluated clinically and radiographically at 1, 3, 6, 9, 12 and 24-month intervals, and the various factors which may affect the success rate were analyzed statistically.
  
  
  RESULTS
  52 cases (88.1%) of 59 patients were considered success, 6 cases (10.2%) were considered failure, and 1 case (1.7%) was considered in progress. The success rate of elderly patients group (63.6%) was significantly lower than that of the youth group (87.5%) and middle-aged group (95.0%) (P = 0.037; P = 0.017). The success rate of molar group (75.0%) was significantly lower than that of the anterior group (92.6%) and the premolar group (90.0%) (P = 0.041, P = 0.047); however, there was no significant difference in the gender, the number of teeth invaded in lesions, the size of periapical lesion (P > 0.05).
  
  
  CONCLUSIONS
  It is an effective therapy for the teeth with large periapical lesions by apical surgery after root canal treatment.
authors.affiliation: Dept. of Stomatology, The Third Hospital of Peking University, Beijing 100191, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Wang
authors.forename: Yuan-Gao
authors.initials: YG
authors.lastname: Li
authors.forename: Xiang-Yong
authors.initials: XY
authors.lastname: Pan
mesh_terms: D000293:Adolescent; D000368:Aged; D001641:Bicuspid; D006801:Humans; D008875:Middle Aged; D008963:Molar; D012387:Root Canal Filling Materials; D012390:Root Canal Therapy; D014092:Tooth Root
chemical_list: D012387:Root Canal Filling Materials