title: Evaluating the association between insulin-like growth factor-1 values and short-term survival rates following acute myocardial infarction.
abstract: BACKGROUND
  In recent years, low levels of Insulin-like Growth Factor-1 (IGF-1) have been suggested to be associated with higher risks of developing heart failure and higher long-term mortality rates following Acute Myocardial Infarction (AMI). However, the effect of IGF-1 levels on short-term survival has been rarely studied. In this study we aimed to assess any possible association between serum IGF-1 concentration following AMI and short-term survival rates.
  
  
  METHODS
  In this study, serum total IGF-1 levels were measured in 56 patients within 24 hours following AMI and were compared to 56 individuals with no cardiovascular disease. Patients were followed up to death or discharge from hospital (median = 6 days) and survival curves were compared based on median IGF-1 value.
  
  
  RESULTS
  Mean (±SD) of serum IGF-1 levels were 232.73 ng/ml (±81.74) and 211.00 ng/ml (±58.22) in survived and expired patients respectively and the difference was not statistically significant (P value = 0.501). The difference between survival curves was also not statistically significant (P value = 0.246).
  
  
  CONCLUSIONS
  According to findings of this study, serum total IGF-1 concentration does not seem to be associated with short-term survival rates.
authors.affiliation: Assistant Cardiology Professor, Rasoul Akram Medical Centre, Tehran, Iran.
authors.forename: Shokoufeh
authors.initials: S
authors.lastname: Hajsadeghi
authors.forename: Hamed
authors.initials: H
authors.lastname: Mohseni
authors.forename: Masoud
authors.initials: M
authors.lastname: Moradi
authors.forename: Elham
authors.initials: E
authors.lastname: Rahmani
authors.forename: Kiarash
authors.initials: K
authors.lastname: Kordshakeri
authors.forename: Mohammad Javad
authors.initials: MJ
authors.lastname: Manteghi
authors.forename: Masoud
authors.initials: M
authors.lastname: Tokazebani
authors.forename: Reza
authors.initials: R
authors.lastname: Mollahoseini