title: [Hypobaric interval hypoxia as a tool for improving tolerance of harmful occupational factors].
abstract: The method of hypobaric interval hypoxia (HIH) has been developed and approved for application in aerospace, military, prophylactic and rehabilitative medicine. A course of H1H included 10 one-hour daily sessions of hypobaria and interval hypoxia simulating ascent to an altitude from 3 to 5 km a.s.l. Each session comprised a 7 minute exposure to hypoxia (breathing rarified air) alternating with a 3 minute exposure to hyperoxia (breathing oxygen) without a change of the altitude simulated in the low-pressure chamber. The first session included ascent to 3 km, in each of the following sessions (from 2nd to 4th) the altitude was successively increased by 500 m and reached 5 km in sessions 5-10. HIH was shown to be highly efficacious in improving the functional state of the organism and its resistance to unfavourable environmental conditions; also it can be used to correct changes of these parameters.
authors.forename: I B
authors.initials: IB
authors.lastname: Ushakov
authors.forename: I V
authors.initials: IV
authors.lastname: Bukhtiiarov
authors.forename: A A
authors.initials: AA
authors.lastname: Shishov
authors.forename: N I
authors.initials: NI
authors.lastname: Olenev
mesh_terms: D000222:Adaptation, Physiological; D000337:Aerospace Medicine; D058109:Airway Management / Q000379:methods*; D000531:Altitude; D001274:Atmospheric Pressure; D003664:Decompression / Q000009:adverse effects / Q000379:methods; D005118:Extraterrestrial Environment; D005790:General Adaptation Syndrome / Q000517:prevention & control / Q000534:rehabilitation / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000517:prevention & control / Q000534:rehabilitation / Q000628:therapy; D000860:Hypoxia / Q000209:etiology*; D009784:Occupational Diseases / Q000517:prevention & control / Q000534:rehabilitation / Q000628:therapy; D009787:Occupational Medicine; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D016896:Treatment Outcome