title: [Long-term neuropsychological impact of type 1 diabetes in children].
abstract: Type 1 diabetes, whose incidence is increasing in the youngest children, could have a long-term neuropsychological impact. Mood disorders are more frequent and some elements of cognitive performance, although within normal ranges, could decrease. In this review, we detail the contribution of animal models to current physiopathological knowledge. We summarize the main clinical studies regarding mood and cognitive performance in diabetic children. Finally, the advantages of imaging in this domain as related to brain development in children are discussed.
authors.affiliation: Service d'endocrinologie et diabétologie de l'enfant et de l'adolescent, hôpital des Enfants, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux, France. pascal.barat@chu-bordeaux.fr
authors.forename: P
authors.initials: P
authors.lastname: Barat
authors.forename: S
authors.initials: S
authors.lastname: Tastet
authors.forename: V
authors.initials: V
authors.lastname: Vautier
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D003072:Cognition Disorders / Q000209:etiology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D004195:Disease Models, Animal; D006801:Humans; D019964:Mood Disorders / Q000209:etiology*; D013997:Time Factors