title: Chemical composition and antibacterial activity of Origanum saccatum P.H. Davis essential oil obtained by solvent-free microwave extraction: comparison with hydrodistillation.
abstract: The components of the essential oils (EOs) obtained by solvent-free microwave extraction (SFME) and hydrodistillation (HD) from endemic Origanum saccatum P.H. Davis were identified by using GC/MS. The main constituents of both EOs obtained by SFME and HD, respectively, from O. saccatum were p-cymene (72.5 and 70.6%), thymol (9.32 and 8.11%), and carvacrol (7.18 and 6.36%). The EO obtained by SFME contained substantially higher amounts of oxygenated compounds and lower amounts of monoterpenes than did the EO obtained by HD. The antibacterial activities of the EOs obtained by SFME and HD were evaluated with the disc diffusion method by comparison with 10 different bacterial strains. The antibacterial activity of the EO extracted by SFME was found to be more effective than that of the EO extracted by HD against seven of the tested bacteria.
authors.affiliation: Akdeniz University, Department of Chemistry, 07058 Antalya, Turkey.
authors.forename: Fazli
authors.initials: F
authors.lastname: Sozmen
authors.forename: Burcu
authors.initials: B
authors.lastname: Uysal
authors.forename: Birsen S
authors.initials: BS
authors.lastname: Oksal
authors.forename: Elif Odabas
authors.initials: EO
authors.lastname: Kose
authors.forename: I Gokhan
authors.initials: IG
authors.lastname: Deniz
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000081007:Cymenes; D057168:Distillation; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D039821:Monoterpenes / Q000302:isolation & purification; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D031341:Origanum / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D012997:Solvents; D013297:Streptococcus pyogenes / Q000187:drug effects; D013943:Thymol / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils; D012997:Solvents; C007210:4-cymene; D013943:Thymol; C073316:carvacrol