title: Colonic dysmotility in constipation.
abstract: Constipation is a common and distressing condition with major morbidity, health care burden, and impact on quality of life. Colonic motor dysfunction remains the leading hypothesis to explain symptom generation in the most severe cases of chronic constipation and physiological testing plays a role in identifying the colonic dysmotility and the subsequent patient management. Measurement of colonic motor patterns and transit has enhanced our knowledge of normal and abnormal colonic motor physiology. The scope of this review encompasses the latest findings that improve our understanding of the motility disorders associated with colonic dysfunction in both the paediatric and adult population suffering from constipation.
authors.affiliation: Department of Gastroenterology, University of New South Wales, St George Hospital, Gray St, Kogarah, NSW 2217, Sydney, Australia. P.Dinning@unsw.edu.au
authors.forename: Philip G
authors.initials: PG
authors.lastname: Dinning
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Lorenzo
mesh_terms: D000328:Adult; D002648:Child; D003106:Colon / Q000503:physiopathology*; D003248:Constipation / Q000175:diagnosis / Q000503:physiopathology*; D003672:Defecation; D003938:Diagnostic Techniques, Digestive System; D005769:Gastrointestinal Motility; D006801:Humans; D008365:Manometry; D011237:Predictive Value of Tests