title: Comprehensive chemical characterization of complexes involving lead-amino acid interactions.
abstract: Complexes of lead with L-phenylalanine, L-isoleucine, L-valine, or L-arginine have been isolated from reaction mixtures containing lead nitrate and the respective amino acid in acidic aqueous solution. The compounds have been comprehensively characterized using X-ray crystallography, solid state NMR spectroscopy and solution state NMR spectroscopy, IR and Raman spectroscopies, and electrospray ionization mass-spectrometry. The solid state structures of lead-phenylalanine, lead-valine, and lead-valine-isoleucine complexes show a lead center coordinated by two amino acid ligands, while the lead-arginine complex is a cluster involving two lead centers and three arginine molecules. The structural, spectroscopic, and spectrometric characterization of the complexes provides a basis to establish a fundamental understanding of heavy metal-amino acid interactions.
authors.affiliation: Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada.
authors.forename: Cheryl D L
authors.initials: CD
authors.lastname: Saunders
authors.forename: Lauren E
authors.initials: LE
authors.lastname: Longobardi
authors.forename: Neil
authors.initials: N
authors.lastname: Burford
authors.forename: Michael D
authors.initials: MD
authors.lastname: Lumsden
authors.forename: Ulrike
authors.initials: U
authors.lastname: Werner-Zwanziger
authors.forename: Banghao
authors.initials: B
authors.lastname: Chen
authors.forename: Robert
authors.initials: R
authors.lastname: McDonald
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007854:Lead / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D009942:Organometallic Compounds; D007854:Lead