title: Perilymphatic subcutaneous fat atrophy and cutaneous depigmentation after periocular triamcinolone acetonide injection in a child.
abstract: Periocular corticosteroid injection is a potent and versatile treatment for uveitic conditions as well as for some ocular tumors. Despite its efficacy, ophthalmologists are wary of documented side effects, some of which can be blinding. Adverse reactions are mostly dependent on route of administration, with glaucoma and cataract formation more often seen in peribulbar and intraocular injections, whereas skin depigmentation and fat atrophy are more frequently related to intradermal or intralesional routes, particularly after injection of capillary hemangioma of infancy. We present a child with perilymphatic linear subcutaneous fat atrophy and depigmentation after sub-Tenon's fascia injection of triamcinolone acetonide.
authors.affiliation: Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Emil Anthony T
authors.initials: EA
authors.lastname: Say
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Carlos
authors.initials: C
authors.lastname: Bianciotto
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D000273:Adipose Tissue / Q000473:pathology*; D001284:Atrophy / Q000139:chemically induced; D001918:Brachytherapy; D005205:Fascia; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D017496:Hypopigmentation / Q000139:chemically induced*; D007223:Infant; D058449:Intravitreal Injections; D019572:Retinal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D012175:Retinoblastoma / Q000188:drug therapy / Q000532:radiotherapy; D012880:Skin Pigmentation / Q000187:drug effects*; D014222:Triamcinolone Acetonide / Q000009:adverse effects*
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide