title: Post-exposure prophylaxis for HIV.
abstract: Definite or suspected occupational exposure of healthcare workers to human immunodeficiency virus (HIV) infection is a medical emergency. Post-exposure prophylaxis (PEP) with antiretroviral drugs is widely available following such exposure, aiming to prevent HIV infection. PEP following non-occupational exposure (nPEP) is also increasingly being provided. The term PEPSE (PEP following sexual exposure) is also commonly used, recognising that most non-occupational exposure is sexual. Here we discuss the evidence supporting the use of PEP and nPEP and advice in current guidelines.
mesh_terms: D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D015438:Health Behavior; D006282:Health Personnel; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000517:prevention & control* / Q000821:virology; D016273:Occupational Exposure / Q000009:adverse effects*; D010353:Patient Education as Topic; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D047568:Unsafe Sex