title: Mothers' knowledge about EPI and its relation with age-appropriate vaccination of infants in peri-urban Karachi.
abstract: OBJECTIVE
  To evaluate the relation between the knowledge of mothers about EPI vaccinations and their infant's coverage. Effect of other socio-demographic variables on mothers' knowledge and child's coverage was also assessed.
  
  
  METHODS
  A cross-sectional survey was conducted, utilizing World Health Organization's thirty-cluster sampling strategy. All households with at least one infant were considered eligible. After obtaining verbal consent, the mother was interviewed to assess her knowledge and attitudes towards EPI vaccination. Infant's coverage status was verified by checking EPI card or verbal inquiry. A knowledge score was developed by summing all correct answers.
  
  
  RESULTS
  A total of 210 mothers (7 per cluster) were identified and interviewed. The number and proportion of mothers correctly identifying the seven EPI diseases were as follows; Tuberculosis 57 (27.1%), Diphtheria 53 (25.2%), Pertussis 71 (33.8%), Tetanus 70 (33.3%), Measles 85 (40.5%), Polio 91 (43.3%) and Hepatitis B 65 (31.0%). Only ninety four (44.8%) children were appropriately vaccinated for their age. In the multivariate model, mothers' knowledge was not significantly associated with appropriate vaccination of their children (p = 0.22), however, mothers' education was found to be significant (p < 0.001).
  
  
  CONCLUSIONS
  Mothers' knowledge about EPI vaccination in peri-urban Karachi was quite low and not associated with their children's EPI coverage. Mothers' educational status, however, was significantly associated with Child's coverage. This finding depicts a better health seeking behaviour of a more educated mother.
authors.affiliation: Department of Epidemiology, Michigan State University, East Lansing, MI, USA.
authors.forename: Nazish
authors.initials: N
authors.lastname: Siddiqi
authors.forename: Azfar-e-alam
authors.initials: AE
authors.lastname: Siddiqi
authors.forename: Nighat
authors.initials: N
authors.lastname: Nisar
authors.forename: Altaf
authors.initials: A
authors.lastname: Khan
mesh_terms: D016000:Cluster Analysis; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data*; D017589:Immunization Programs / Q000458:organization & administration* / Q000706:statistics & numerical data; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009035:Mothers; D010154:Pakistan; D010342:Patient Acceptance of Health Care; D012959:Socioeconomic Factors; D018881:Suburban Health; D011795:Surveys and Questionnaires; D014504:Urban Health; D014944:World Health Organization