title: Phosphine-catalyzed [4 + 1] annulation between α,β-unsaturated imines and allylic carbonates: synthesis of 2-pyrrolines.
abstract: In this report, a phosphine-catalyzed [4 + 1] annulation between α,β-unsaturated imines and allylic carbonates is described. This reaction represents the first realization of catalytic [4 + 1] cyclization of 1,3-azadienes with in situ formed phosphorus ylides, which provides highly efficient and diastereoselective synthesis of 2-pyrrolines.
authors.affiliation: The State Key Laboratory of Elemento-Organic Chemistry and Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
authors.forename: Junjun
authors.initials: J
authors.lastname: Tian
authors.forename: Rong
authors.initials: R
authors.lastname: Zhou
authors.forename: Haiyun
authors.initials: H
authors.lastname: Sun
authors.forename: Haibin
authors.initials: H
authors.lastname: Song
authors.forename: Zhengjie
authors.initials: Z
authors.lastname: He
mesh_terms: D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D002254:Carbonates; D007097:Imines; D010720:Phosphines; D011758:Pyrroles; C013231:pyrroline; C044646:phosphine