title: In vivo assays of langerhans cell migration.
abstract: The skin is an immunologically active tissue; the integrated skin immune system comprises epidermal Langerhans cells (LC), dermal dendritic cells (DC), tissue macrophages, mast cells, and T lymphocytes in transit. Cutaneous immune function is orchestrated through the action of cytokines produced locally in the skin by LC, keratinocytes, and other cell types (1-3).
authors.affiliation: Syngenta Central Toxicology Laboratory, Macclesfield, UK.
authors.forename: M
authors.initials: M
authors.lastname: Cumberbatch
authors.forename: R J
authors.initials: RJ
authors.lastname: Dearman
authors.forename: I
authors.initials: I
authors.lastname: Kimber