title: Quantitative modeling of limitations caused by diffusion.
abstract: Transport of nutrients and metabolites in many bioartificial tissue constructs relies exclusively on diffusion, i.e., on the presence of a concentration gradient between the inside of the construct and the surrounding milieu. A quantitative evaluation of the rate of diffusional processes is thus essential for properly designing three-dimensional cell-polymer systems, and for assessing the chemical environment at various locales within the construct.
authors.affiliation: School of Chemical Engineering and Parker H.Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA.
authors.forename: A
authors.initials: A
authors.lastname: Sambanis
authors.forename: S A
authors.initials: SA
authors.lastname: Tan