title: Does use of intraoperative cell-salvage delay recovery in patients undergoing elective abdominal aortic surgery?
abstract: A best evidence topic in vascular surgery was written according to a structured protocol. The question addressed was whether the use of intraoperative cell-salvage (ICS) leads to negative outcomes in patients undergoing elective abdominal aortic surgery? Altogether 305 papers were found using the reported search, of which 10 were judged to represent the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers were tabulated. None of the 10 papers included in the analysis demonstrated that ICS use led to significantly higher incidence of cardiac or septic postoperative complications. Similarly, length of intensive treatment unit (ITU) or hospital stay and mortality in elective abdominal aortic surgery were not adversely affected. Indeed two trials actually show a significantly shorter hospital stay after ICS use, one a shorter ITU stay and another suggests lower rates of chest sepsis. Based on these papers, we concluded that the use of ICS does not cause increased morbidity or mortality when compared to standard practise of transfusion of allogenic blood, and may actually improve some clinical outcomes. As abdominal aortic surgery inevitably causes significant intraoperative blood loss, in the range of 661-3755 ml as described in the papers detailed in this review, ICS is a useful and safe strategy to minimise use of allogenic blood.
authors.affiliation: Section of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK. aniket.tavare@gmail.com
authors.forename: Aniket N
authors.initials: AN
authors.lastname: Tavare
authors.forename: Nassim
authors.initials: N
authors.lastname: Parvizi
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery*; D019985:Benchmarking; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001804:Blood Transfusion, Autologous / Q000009:adverse effects; D017558:Elective Surgical Procedures; D019317:Evidence-Based Medicine; D006801:Humans; D007362:Intensive Care Units; D007902:Length of Stay; D008297:Male; D057725:Operative Blood Salvage / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects