title: Naturally occurring biodegradable polymers as the basis of chiral gels for the distinction of enantiomers by partially oriented NMR spectroscopy.
abstract: BACKGROUND
  In modern, high resolution NMR spectroscopy, anisotropic parameters play an important role. They can be measured with the help of liquid crystalline mesophases or stretched polymer gels as so-called alignment media. Biologically occurring chiral polymers are of special interest as alignment media for this technique because they allow enantiomers to be distinguished.
  
  
  METHODS
  Biopolymers have been studied by deuterium 1D and J-BIRDd,X-HSQC NMR experiments with respect to their ability to distinguish enantiomers and a summary of existing biopolymers for the task is given.
  
  
  RESULTS
  Gelatin is shown to distinguish D-proline from L-proline and next to already known biopolymers, gellan gum is introduced as a novel biologically derived polymer that is able to partially align solute molecules.
  
  
  CONCLUSIONS
  Biologically occurring and biodegradable polymers are well suited as alignment media and in many cases are able to distinguish enantiomers. As the orienting properties are different for different media and solute molecules, the bandwidth of corresponding polymers will be further increased in the future.
authors.affiliation: Institute of Organic Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany.
authors.forename: Silke S D
authors.initials: SS
authors.lastname: Büchler
authors.forename: Grit
authors.initials: G
authors.lastname: Kummerlöwe
authors.forename: Burkhard
authors.initials: B
authors.lastname: Luy
mesh_terms: D020341:Absorbable Implants; D016880:Anisotropy; D005780:Gelatin / Q000737:chemistry*; D005782:Gels; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D011392:Proline / Q000737:chemistry*
chemical_list: D005782:Gels; D011135:Polysaccharides, Bacterial; C048288:gellan gum; D005780:Gelatin; D011392:Proline