title: Vasectomizing a mouse.
abstract: Vasectomized males are needed to engender pseudopregnancy in mature female mice. Such pseudopregnant females act as hormonally and physiologically competent recipients for microinjected fertilized one-cell eggs (see Chapter 20). Vasectomized males retain their sexual potency and leave a copulatory plug after mating, but, of course, fail to transmit any sperm. Some laboratories use genetically sterile males for this purpose rather than mice rendered sterile by surgery.
authors.affiliation: Neuropeptide Laboratory, Institute of Molecular and Cell Biology, National University of Singapore, Republic of Singapore.
authors.forename: D
authors.initials: D
authors.lastname: Murphy
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D051379:Mice; D014659:Vasectomy / Q000379:methods*