title: Complete remission of renal cell carcinoma with lung metastases in two hemodialysis patients after low-dose interferon therapy.
abstract: A standard immunotherapy strategy for metastatic renal cell carcinoma (RCC) in dialysis patients has yet to be established. In this study, we report complete remission of RCC with lung metastases in 2 hemodialysis patients after low-dose interferon therapy (Sumiferon® 3 × 10⁶ international unit 3 times a week). These results suggest that interferon therapy is important for clear cell RCC with lung metastases in dialysis patients, even in the era of molecular-targeted therapies.
authors.affiliation: Department of Urology, Nippon Medical School, Chiba Hokusoh Hospital, Chiba, Japan. k-n@nms.ac.jp
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nemoto
authors.forename: Takafumi
authors.initials: T
authors.lastname: Miura
authors.forename: Go
authors.initials: G
authors.lastname: Shioji
authors.forename: Narumi
authors.initials: N
authors.lastname: Tsuboi
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D016898:Interferon-alpha / Q000008:administration & dosage*; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012074:Remission Induction; D006435:Renal Dialysis
chemical_list: D016898:Interferon-alpha