title: Hypothalamic-pituitary gland axis function and dysfunction in horses.
abstract: Hypothalamic-pituitary (HP) dysfunction has been documented in a limited capacity in horses and foals associated with critical illness, stress, and pain. This article reviews species-specific details of anatomy, function, hormones, receptors, and testing of the HP axis in the horse. A discussion of critical care medicine relevant to HP dysfunction in the horse with some reference to current understanding in human medicine is made, focusing primarily on current and relevant literature. A brief mention of other conditions described in human and veterinary medicine is also provided for reference only, such as syndrome of inappropriate antidiuretic hormone secretion and other conditions.
authors.affiliation: Department of Veterinary Clinical Sciences, Galbreath Equine Center, The Ohio State University, 601 Vernon L Tharp Street, Columbus, OH 43210, USA. Samuel.Hurcombe@cvm.osu.edu
authors.forename: Samuel D A
authors.initials: SD
authors.lastname: Hurcombe
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006734:Horse Diseases / Q000503:physiopathology*; D006736:Horses; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology* / Q000503:physiopathology*; D008297:Male; D010913:Pituitary-Adrenal System / Q000502:physiology* / Q000503:physiopathology*