title: Epidemiological profile of adult patients with tuberculosis and AIDS in the state of Espírito Santo, Brazil: cross-referencing tuberculosis and AIDS databases.
abstract: OBJECTIVE
  To evaluate the epidemiological profile of patients with tuberculosis (TB) only and that of patients with TB/AIDS in the state of Espírito Santo, Brazil, between 2000 and 2006.
  
  
  METHODS
  For the patients of interest, we collected demographic and clinical data from the Epidemiological Surveillance Center (TB database), Brazilian Case Registry Database, and Brazilian National Mortality Database, as well as the Brazilian National CD4+/CD8+ T Lymphocyte Count and Viral Load Network Laboratory Test Control System and the Logistic Medication Monitoring System (HIV/AIDS databases). All of the compiled data were cross-referenced.
  
  
  RESULTS
  During the study period, we identified 9,543 TB patients > 15 years of age, 437 of whom (4.6%) had AIDS. The median age did not differ between TB/AIDS and TB-only patients (35 years vs. 38 years). Of the 437 TB/AIDS patients, 298 (68.2%) were male, and 156 (35.8%) were in the 30-39 age bracket. In terms of TB treatment outcome, 79.0% were cured, 9.7% were referred to other facilities, 6.0% died, 5.2% abandoned treatment, and 0.2% developed multidrug-resistant TB. Death was 4.75 times more common in patients with TB/AIDS than in those with TB only. Pulmonary TB accounted for 82.4% of the cases. The combination of pulmonary and extrapulmonary TB was 8.2 times more common in the TB/AIDS patients than in the TB-only patients (95% CI: 6.2-10.8).
  
  
  CONCLUSIONS
  Our results emphasize the significance of AIDS among TB patients in Brazil, as well as the importance of evaluating secondary data in order to improve their quality and develop public health interventions.
authors.affiliation: Federal University of Espírito Santo, Vitória, Brazil.
authors.forename: Thiago Nascimento do
authors.initials: TN
authors.lastname: Prado
authors.forename: Antonio Luiz
authors.initials: AL
authors.lastname: Caus
authors.forename: Murilo
authors.initials: M
authors.lastname: Marques
authors.forename: Ethel Leonor
authors.initials: EL
authors.lastname: Maciel
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Golub
authors.forename: Angélica Espinosa
authors.initials: AE
authors.lastname: Miranda
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D015897:Comorbidity; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology*; D055815:Young Adult