title: Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization.
abstract: A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8548, Japan.
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Tienan
authors.initials: T
authors.lastname: Jin
authors.forename: Ming
authors.initials: M
authors.lastname: Bao
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D002074:Butanones / Q000737:chemistry; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*
chemical_list: D002074:Butanones; D005663:Furans; D007455:Iodine