title: [Therapeutic effect of Rabdosia rubescens aqueous extract on chronic pharyngitis and its safety].
abstract: OBJECTIVE
  To evaluate the clinical therapeutic effect of Rabdosia rubescens aqueous extract on chronic pharyngitis and its safety.
  
  
  METHODS
  One hundred and two patients suffered from chronic pharyngtis were randomly divided into an interventional group (n=51) and a placebo group (n=51). These volunteers were given 220 mL test materials once a day double-blindly for 30 days. All patients took routine physical examinations, and their throat symptom and pharynx signs were observed before and after the experiment.
  
  
  RESULTS
  After the patients had consumed Rabdosia rubescens aqueous extract and the placebo for 30 days, the improvement rates of main clinical symptom and signs in the interventional group were 67.31% and 61.54%, while those in placebo group were 19.23% and 11.54%, with significant difference (P<0.05). Before the experiment, the integral of main clinical symptom and signs between the two groups did not show significant difference (P>0.05). But after 30 days, the integral of main clinical symptom and signs in the interventional group significantly decreased (P<0.05), compared with itself before the experiment and the placebo group.
  
  
  CONCLUSIONS
  Rabdosia rubescens aqueous extract is safe and effective for patients with chronic pharyngitis.
authors.affiliation: Hunan Center for Disease Control and Prevention, Changsha 410005, China. 1846685@qq.com
authors.forename: Zheng
authors.initials: Z
authors.lastname: Ma
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Hu
authors.forename: Yingying
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D037602:Isodon / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D010612:Pharyngitis / Q000188:drug therapy*; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal