title: [Teratozoospermia, myth or reality? A 10-years retrospective study on 101404 consecutive sperm samples].
abstract: OBJECTIVE
  Several studies have reported a time-related decline in semen quality. In this context, 101,404 spermograms-spermocytograms performed in a single andrology laboratory from January 2000 to December 2009 were investigated retrospectively. Variations of sperm parameters were analyzed over the years.
  
  
  METHODS
  For each semen sample, age at semen collection, duration of sexual abstinence, volume of seminal fluid, pH, concentration of spermatozoa, percentages of overall motile and progressive motile sperm, percentage of morphologically abnormal spermatozoa (according to David's classification) and amplitude of lateral head displacement (ALH) were analyzed. For each parameter, the mean value per year was determined. To examine trends over time the statistical tests used were analyses of variance and correlation studies.
  
  
  RESULTS
  Data showed an increasing age of patients from 36.5 years in 2000 to 37.2 years in 2009. The semen concentration was 63.5 millions/mL in 2000 and 63.6 millions/mL in 2009 with a slight fall from 2001 to 2008. The vitality continuously increased from 67.8% in 2000 to 73.5% in 2009 as well as the overall motility (from 37.7% to 39.2%) and the progressive motility (from 34.6% to 36.2%). The percentage of morphologically abnormal spermatozoa continuously increased from 64.5% to 84.2% (r=0.43, P<0.001).
  
  
  CONCLUSIONS
  Contrary to a variety of works, our very large study of semen analysis did not show a real decline in semen WHO parameters during a 10-year period, except for the percentage of morphologically abnormal spermatozoa, which dramatically increased over the years.
authors.affiliation: Laboratoire d'Eylau-Unilabs, 55-57 rue Saint-Didier, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Prisant
authors.forename: P
authors.initials: P
authors.lastname: Cohen-Bacrie
authors.forename: E
authors.initials: E
authors.lastname: Amar
authors.forename: J
authors.initials: J
authors.lastname: Belaisch-Allart
authors.forename: M
authors.initials: M
authors.lastname: Cohen-Bacrie
authors.forename: F
authors.initials: F
authors.lastname: Olivennes
authors.forename: F-X
authors.initials: FX
authors.lastname: Aubriot
authors.forename: S
authors.initials: S
authors.lastname: Belloc
mesh_terms: D000328:Adult; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D012189:Retrospective Studies; D055101:Semen Analysis; D013076:Sperm Count; D013077:Sperm Head / Q000648:ultrastructure; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities* / Q000502:physiology