title: [Experimental rationale for approaches to the development and evaluation of new functional foodstuffs].
abstract: This comprehensive experimental study had the objective to determine the optimum ratio of calcium and vitamin D used as additives in food compositions and provide an experimentally-based rationale for the use of new functional dairy products and evaluation of their nutritional value. Experimental medico-biological assessment was conducted using growing male Wistar rats by balance and biochemical methods. It was shown that the calcium/vitamin D ratio in foodstuffs determines their functional efficiency. High nutritive and biological value was documented for some new cottage cheese products rich in calcium (240 mg%) and vitamin D (1 mg%). Results of the study were used to develop guidelines for the enrichment of various food compositions with calcium and vitamin D and substantiate methods for the assessment of their real functional effectiveness.
authors.forename: A A
authors.initials: AA
authors.lastname: Korolev
authors.forename: E I
authors.initials: EI
authors.lastname: Nikitenko
authors.forename: A V
authors.initials: AV
authors.lastname: Malakhova
authors.forename: V A
authors.initials: VA
authors.lastname: Kudasheva
authors.forename: A I
authors.initials: AI
authors.lastname: Gorshkov
mesh_terms: D000818:Animals; D015415:Biomarkers; D002113:Calcification, Physiologic / Q000187:drug effects; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000378:metabolism; D002611:Cheese / Q000032:analysis / Q000592:standards; D018795:Device Approval; D005526:Food, Formulated / Q000032:analysis / Q000592:standards; D005527:Food, Fortified / Q000032:analysis / Q000592:standards; D055951:Functional Food / Q000032:analysis / Q000592:standards; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D008991:Monitoring, Physiologic; D044623:Nutrition Therapy / Q000379:methods; D009751:Nutritional Requirements; D009753:Nutritive Value; D051381:Rats; D017208:Rats, Wistar; D014807:Vitamin D / Q000008:administration & dosage / Q000378:metabolism
chemical_list: D015415:Biomarkers; D002136:Calcium, Dietary; D014807:Vitamin D; D008315:Malondialdehyde