title: HCV Genotyping by the Line Probe Assay INNO-LiPA HCV II.
abstract: Hepatitis C viruses (HCVs) constitute a highly variable genus within the Flaviviridae, with closest homology to the hepatitis G and GB viruses, and Pestiviruses. The positive-stranded RNA genome encodes a polyprotein which is co- and posttranslationally cleaved into at least nine proteins. Core, E1, and E2 (the structural proteins) and NS2, NS3, NS4A, NS4B, NS5A, and NS5B (the nonstructural [NS] proteins). A theoretical protein of 7 kDa (tp7) may be processed from the carboxy terminal E2 region (1).
authors.affiliation: Hepatitis Program, Innogenetics, Gent, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Maertens
authors.forename: L
authors.initials: L
authors.lastname: Stuyver