title: Molecular characteristics and antitumor capacity of Glycan extracted from Cynomorium songaricum.
abstract: Glycan were isolated from Cynomorium songaricum and flavone was extracted from Ginkgo leaf. This glycan was well fractionated into three fractions (CSG-F1, CSG-F1, and CSG-F3). The spectra were recorded at the absorbance mode from 4000 to 400 cm(-1) (mid infrared region) at the resolution of 8 cm(-1). The fourier transform infrared (IR) spectrum displayed a broad peak at 3438 cm(-1) and 2928 cm(-1) that corresponded to the stretching vibration of -OH group. The Ginkgo leaf flavone markedly inhibited the growth of human liver carcinoma cell line HepG2. However, C. songaricum glycan did not displayed strong antitumor activity.
authors.affiliation: Department of Medicine & Oncology, the Third Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: Guangyue
authors.initials: G
authors.lastname: Shi
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Cai
authors.forename: Guangjie
authors.initials: G
authors.lastname: Sui
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D005591:Chemical Fractionation; D031482:Cynomorium / Q000737:chemistry*; D047309:Flavones / Q000494:pharmacology; D020441:Ginkgo biloba / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D009369:Neoplasms / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013481:Superoxides / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D047309:Flavones; D010936:Plant Extracts; D011134:Polysaccharides; D013481:Superoxides; C043562:flavone