title: [Changes in visual evoked potentials in developmental age. Comparative studies of pattern reversal and two types of flash stimulation].
abstract: BACKGROUND
  Examination of visual evoked potentials (VEP) enables objective, non-invasive diagnostics of vision damage in children and adolescents. It is important to choose proper stimulus for individual patient.
  
  
  OBJECTIVE
  The aim of this research was analysis of VEP variability and disclosure of possible differences recorded in healthy children and adolescents while binocular recording, using four various types of stimulus.
  
  
  METHODS
  VEPs with pattern reversal (PR 15 and 40 min arc), flashing screen and light emitting diodes (LEDs) in goggles were measured in 100 children and adolescents 1-18 year according to International Federation of Clinical Neurophysiology recommendations. Normative data for VEP's parameters and hemispheric differences under these kinds of simulations were reported.
  
  
  RESULTS
  Influence of used stimulation on value of only VEP component latency was confirmed. Application of PR brings longer latencies than with use of flash methods. Changes of VEP parameters connected with maturation of visual pathway in children up to age of 8 were demonstrated. The constant value of responses registered from above left and right cerebral hemispheres was observed which indicates symmetry of recording obtained.
  
  
  CONCLUSIONS
  Variability of VEP recording character depends on application of various stimulus parameters and various methods of their presentations. Consequently, every laboratory performing potential examinations should establish parameter pattern of VEP with strictly defined standardized conditions of stimulation and recording.
authors.affiliation: Uniwersytet Medyczny im. K. Marcinkowskiego, Poznań. neuro@ump.edu.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Zgorzalewicz-Stachowiak
authors.forename: Zuzanna
authors.initials: Z
authors.lastname: Bartkowiak
authors.forename: Bozena
authors.initials: B
authors.lastname: Galas-Zgorzalewicz
mesh_terms: D000293:Adolescent; D041923:Adolescent Development / Q000502:physiology*; D002648:Child; D002657:Child Development / Q000502:physiology; D002675:Child, Preschool; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010775:Photic Stimulation / Q000379:methods*; D012016:Reference Values; D015203:Reproducibility of Results