title: Embryonal rhabdomyosarcoma of the adult soft palate.
abstract: Embryonal rhabdomyosarcoma is the most common soft tissue sarcoma in children. We report a rare case of embryonal rhabdomyosarcoma of the soft palate in a 32-year-old Caucasian female. Detailed histology of the tumor is described. Positive staining with desmin, myogenin and myoD1 confirmed the tumor to be embryonal rhabdomyosarcoma. A genetic association between rhabdomyosarcoma, polycystic ovary syndrome and the FEM1A gene on the human chromosome is speculated upon.
authors.affiliation: Department of ENT, Altnagelvin Area Hospital, Londonderry, BT47 6SB, United Kingdom. drsamarbhutoria@yahoo.co.uk
authors.forename: Samar
authors.initials: S
authors.lastname: Bhutoria
authors.forename: Ciaran
authors.initials: C
authors.lastname: Oneil
mesh_terms: D000328:Adult; D003893:Desmin / Q000032:analysis; D005260:Female; D006257:Head / Q000000981:diagnostic imaging; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008853:Microscopy; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D017570:MyoD Protein / Q000032:analysis; D018008:Myogenin / Q000032:analysis; D010160:Palate, Soft / Q000473:pathology*; D011859:Radiography; D018233:Rhabdomyosarcoma, Embryonal / Q000175:diagnosis* / Q000473:pathology*; D044465:White People
chemical_list: D003893:Desmin; D017570:MyoD Protein; C057363:MyoD1 myogenic differentiation protein; D018008:Myogenin