title: Analgesic-like activity of essential oils constituents.
abstract: Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.
authors.affiliation: Department of Physiology, Federal University of Sergipe, CEP 49100-000, São Cristóvão, SE, Brazil. damiao_desousa@yahoo.com.br
authors.forename: Damião Pergentino
authors.initials: DP
authors.lastname: de Sousa
mesh_terms: D000700:Analgesics / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000700:Analgesics; D009822:Oils, Volatile