title: ["Low infusion resuscitation" in the treatment of wounded and injured with acute massive blood loss].
abstract: Acute massive blood loss (AMBL) of severe and extremely severe degree is still one of the leading causes of unfavourable traumatic disease. 95% of potentially preventable lethal outcomes in severe gunshot trauma is reported to depend largely on the adequacy of AMBL correction (Howard P., 2003). An alternate approach to the issue studied was the development of preparations of hyperosmotic saline solutions (7.5% sodium chloride) combined with hyperoncotic colloid solutions (dextrans, hetastarch). As a result, solutions were developed (so-called, hyperosmotic hyperoncotic volume expanders) allowing to achieve rapid and stable volemic and hemodynamic effect in case of low volume infusion (usually, 4 ml/kg of body weight). The present study allowed to conclude that "low infusion resuscitation" technique in patients with multiple trauma accompanied by acute massive blood loss of extremely severe degree enables to reduce lethality, to achieve early subcompesatory hemodynamic state in acute traumatic disease.
authors.forename: I M
authors.initials: IM
authors.lastname: Samokhvalov
authors.forename: S V
authors.initials: SV
authors.lastname: Gavrilin
authors.forename: K P
authors.initials: KP
authors.lastname: Golovko
authors.forename: D P
authors.initials: DP
authors.lastname: Meshakov
authors.forename: S V
authors.initials: SV
authors.lastname: Nedomolkin
authors.forename: V V
authors.initials: VV
authors.lastname: Denisenko
authors.forename: A A
authors.initials: AA
authors.lastname: Pichugin
authors.forename: K P
authors.initials: KP
authors.lastname: Kuneev
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D006438:Hemodilution / Q000379:methods*; D006439:Hemodynamics; D006470:Hemorrhage / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008889:Military Personnel; D009104:Multiple Trauma / Q000150:complications / Q000401:mortality / Q000628:therapy*; D010952:Plasma Substitutes / Q000008:administration & dosage*; D012151:Resuscitation / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D010952:Plasma Substitutes