title: Influenza C virus surveillance during the first influenza A (H1N1) 2009 pandemic wave in Catalonia, Spain.
abstract: Although particular attention is paid to influenza A and B virus isolates during influenza surveillance, influenza C virus (FLUCV) coexisted during the first influenza A (H1N1) 2009 pandemic wave during the 2009-2010 season. From 27 April 2009 to 9 May 2010, 12 strains of FLUCV were detected in specimens collected from 1713 nonhospitalized patients with upper respiratory tract illness using a molecular method. Half of the patients with FLUCV infection were older than 14 years. The most frequent symptoms were cough and fever, similar to other viral respiratory infections. Phylogenetic analysis of the hemagglutinin-esterase gene revealed that the strains belonged to the C/Kanagawa/1/76-related and C/Sao Paulo/378/82-related lineages, demonstrating their co-circulation in Catalonia. In addition to regular virological surveillance that provides information about the incidence and the exact role of FLUCV in acute viral respiratory infections in the general population, the genetic lineage identification offers additional data for epidemiological purposes.
authors.affiliation: Virology Section, Microbiology Department, Barcelona Centre for International Health Research (CRESIB, Hospital Clínic - Universitat de Barcelona), 08036 Barcelona, Spain. ananton@clinic.ub.es
authors.forename: Andrés
authors.initials: A
authors.lastname: Antón
authors.forename: María A
authors.initials: MA
authors.lastname: Marcos
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Codoñer
authors.forename: Patricia
authors.initials: P
authors.lastname: de Molina
authors.forename: Anna
authors.initials: A
authors.lastname: Martínez
authors.forename: Neus
authors.initials: N
authors.lastname: Cardeñosa
authors.forename: Pere
authors.initials: P
authors.lastname: Godoy
authors.forename: Nuria
authors.initials: N
authors.lastname: Torner
authors.forename: Miguel J
authors.initials: MJ
authors.lastname: Martínez
authors.forename: Susana
authors.initials: S
authors.lastname: Ramón
authors.forename: Griselda
authors.initials: G
authors.lastname: Tudó
authors.forename: Ricard
authors.initials: R
authors.lastname: Isanta
authors.forename: Verónica
authors.initials: V
authors.lastname: Gonzalo
authors.forename: María T Jiménez
authors.initials: MT
authors.lastname: de Anta
authors.forename: Tomàs
authors.initials: T
authors.lastname: Pumarola
mesh_terms: D000293:Adolescent; D000328:Adult; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000235:genetics; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D009982:Gammainfluenzavirus / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D058873:Pandemics; D010802:Phylogeny; D011159:Population Surveillance; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000821:virology*; D013030:Spain / Q000453:epidemiology; D014760:Viral Fusion Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D006389:Hemagglutinins, Viral; D014760:Viral Fusion Proteins; C060814:hemagglutinin esterase