title: Intracoronary thrombin injection using a microcatheter to treat guidewire-induced coronary artery perforation.
abstract: Coronary artery perforation (CAP) is an infrequent yet a very dangerous complication of percutaneous coronary intervention. We describe the successful treatment of a guidewire-induced distal coronary branch vessel perforation using localized distal injection of intracoronary thrombin with a microcatheter. This technique appears to be safe and effective for the treatment of life-threatening distal guidewire perforations, even in the smallest tertiary coronary branches.
authors.affiliation: Borgess Heart Institute, Michigan State University, Kalamazoo, MI 49048, USA. tafisc@gmail.com
authors.forename: Tim A
authors.initials: TA
authors.lastname: Fischell
authors.forename: Soundos K
authors.initials: SK
authors.lastname: Moualla
authors.forename: Santhosh R
authors.initials: SR
authors.lastname: Mannem
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D057785:Catheters; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000293:injuries; D004867:Equipment Design; D006335:Heart Injuries / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008845:Microinjections; D009203:Myocardial Infarction / Q000628:therapy; D013917:Thrombin / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D013917:Thrombin