title: In situ hybridization.
abstract: In situhybridization permits specific identification of genes and gene expression without removing the target sequence from its topographical surroundings. The technique was described simultaneously in 1960 by two groups (1,2). It depends on the hybridization of a labeled nucleic acid probe to a complementary sequence of tissue mRNA or DNA.
authors.affiliation: Department of Gastroenterology, Bradford Royal Informary, Bradford, West Yorkshire, UK.
authors.forename: C G
authors.initials: CG
authors.lastname: Beckett
authors.forename: P J
authors.initials: PJ
authors.lastname: Ciclitira