title: [Features of microflora of nasal mucosa in patients with acute and chronic inflammatory processes of upper respiratory tract during diagnosed Chlamydia infection].
abstract: OBJECTIVE
  Comparative study of microflora of nasal passages during acute and chronic inflammatory nasal diseases with and without Chlamydia infection.
  
  
  METHODS
  Microflora of nasal mucosa obtained from 104 patients with acute maxillary sinusitis and chronic nasal diseases (sinusitis and rhinitis) with and without detected Chlamydia infection. Verification of the latter was performed by PCR and direct immunofluorescent method. Microbiological isolation was performed on blood agar using method of sectors. Identification of streptococci, bacteria from Enterobacteriaceae family, staphylococci, and bacteria from Neisseria genus was performed by conventional methods.
  
  
  RESULTS
  During acute maxillary sinusitis associated with Chlamydia infection, depletion of bacterial species diversity was observed with increase of quantity of staphylococci. Also, increase of number of staphylococcal strains with pathogenic properties in patients with Chlamydia carriage was observed.
  
  
  CONCLUSIONS
  It could be suggested that Chlamydia, pathogenic, and opportunistic bacteria are antagonists, which compete for ecologic niche and substrate in host organism. Decrease of number of staphylococci is a response on invasion and multiplication of Chlamydia on mucosa of nasal passages.
authors.forename: O A
authors.initials: OA
authors.lastname: Kolenchukova
authors.forename: T A
authors.initials: TA
authors.lastname: Kapustina
mesh_terms: D001419:Bacteria / Q000302:isolation & purification* / Q000472:pathogenicity; D058491:Bacterial Load; D002690:Chlamydia Infections / Q000150:complications* / Q000175:diagnosis; D002692:Chlamydia trachomatis; D002908:Chronic Disease; D006801:Humans; D009297:Nasal Mucosa / Q000382:microbiology*; D012220:Rhinitis / Q000150:complications / Q000382:microbiology*; D012852:Sinusitis / Q000150:complications / Q000382:microbiology*; D014774:Virulence