title: [Ibuprofen release preferences of medicinal products, the market share of excipients vement of a polymer].
abstract: On pharmaceutical market, beside technological variability of the forms of a drug with ibuprofen, there also occurs variability of chemical and crystallographic forms of ibuprofen itself. The above allows to use ibuprofen not only in the form of pure acid, but also forms of ibuprofen sodium salts or hydrophilic solubilized complexes of very good solubility in water. The above influences changeability of technological parameters measured with the use of methods of quality control being the pharmacopeal standard. On the basis of information collected in pharmacies, it can be also considered that pharmacological effect of identical forms of drugs with ibuprofen in the same dose is differently perceived by patients expecting comfort of the process of treatment, the result of which is to be effective. The above arguments induce undertaking studies on the estimation of differences occurring between particular market versions of the forms of a drug with ibuprofen.
authors.affiliation: Zakład Technologii Postaci Leku, Katedra Farmacji Stosowanej, Uniwersytet Medyczny w Łodzi. michal.kolodziejczyk@umed.lodz.pl
authors.forename: Michał Krzysztof
authors.initials: MK
authors.lastname: Kołodziejczyk
authors.forename: Justyna
authors.initials: J
authors.lastname: Kołodziejska
authors.forename: Marian Mikołaj
authors.initials: MM
authors.lastname: Zgoda
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D005079:Excipients / Q000737:chemistry*; D007052:Ibuprofen / Q000737:chemistry*; D012995:Solubility; D012996:Solutions / Q000737:chemistry
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005079:Excipients; D012996:Solutions; D007052:Ibuprofen