title: [Effects of acupuncture combined with dietary adjustments and aerobic exercise on body weight, body mass index and serum leptin level in simple obesity patients].
abstract: OBJECTIVE
  To observe the effect of acupuncture combined with dietary adjustments and aerobic exercise on the body weight, body mass index (BMI) and serum leptin content of patients with simple obesity, so as to evaluate the efficacy of the present therapy in the treatment of simple obesity.
  
  
  METHODS
  A total of 61 cases of out-patients were randomly divided into control (n=30) and treatment (n=31) groups. Patients in the control group were treated with dietary adjustments and aerobic exercise everyday (30 min/d), continuously for 51 days, and those of the treatment group were treated with acupuncture [Zhong-wan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), etc.] plus dietary adjustment and aerobic exercise everyday, with 15 days being a course of treatment, 3 days' interval between every two courses, and 3 courses altogether. Serum leptin content was detected by using radioimmunoassay.
  
  
  RESULTS
  Compared with pre-treatment, the body weight and BMI and serum leptin levels in the control and treatment groups were all decreased significantly (P < 0.01). Comparison between the two groups showed that the body weight at the end of the 1st and 3rd course of treatment, the BMI at the end of the 1st, 2nd and 3rd course of treatment, and serum leptin level after the treatment in the treatment group were all significantly lower than those in the control group (P < 0.05, P < 0.01). The difference values of body weight and BMI between pre-treatment and post-treatment of the treatment group were obviously higher than those of the control group (P < 0.01), suggesting a better therapeutic effect of acupuncture combined with dietary adjustments and aerobic exercise in the treatment of simple obesity.
  
  
  CONCLUSIONS
  Acupuncture combined with dietary adjustments and aerobic exercise can reduce the body weight, BMI and serum leptin level, which is better than dietary adjustments plus aerobic exercise.
authors.affiliation: Department of Acu-moribustion, College of Chinese Medicine, Hebei Medical University, Shijiazhuang 050091, China. 1952yjj@163.com
authors.forename: Ji-jun
authors.initials: JJ
authors.lastname: Yang
authors.forename: Hai-jiao
authors.initials: HJ
authors.lastname: Xing
authors.forename: Shao-jin
authors.initials: SJ
authors.lastname: Wang
authors.forename: Hong-ling
authors.initials: HL
authors.lastname: Xiao
authors.forename: Mei
authors.initials: M
authors.lastname: Li
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
mesh_terms: D015670:Acupuncture Therapy; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D001835:Body Weight; D003131:Combined Modality Therapy; D015444:Exercise; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult
chemical_list: D020738:Leptin