title: Aqueous-phase deactivation and intramolecular [2 + 2 + 2] cycloaddition of oxanorbornadiene esters.
abstract: Both inter- and intramolecular degradation pathways were identified for the aqueous phase deactivation of oxanorbornadiene (OND) electrophiles, and propargylic OND esters were found to undergo facile intramolecular [2 + 2 + 2] homo-Diels-Alder cycloaddition in polar media.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Kislukhin
authors.forename: Cody J
authors.initials: CJ
authors.lastname: Higginson
authors.forename: M G
authors.initials: MG
authors.lastname: Finn
mesh_terms: D003500:Cyclization; D004952:Esters / Q000138:chemical synthesis*; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*
chemical_list: D004952:Esters; D010087:Oxides