title: A mild oxidative aryl radical addition into alkenes by aerobic oxidation of arylhydrazines.
abstract: A mild and practical oxyarylation of alkenes by oxidative radical addition has been developed by using aerobic oxidation of hydrazine compounds. The use of a catalytic amount of potassium ferrocyanide trihydrate (K(4)[Fe(CN)(6)]⋅3H(2)O) and water accelerated this radical reaction to give peroxides or alcohols from simple alkenes in good yields. The environmentally friendly and economical radical reactions were achieved at room temperature in the presence of iron catalyst, oxygen gas, and water. A method involving aniline as a radical precursor is also described.
authors.affiliation: School of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa 920-1192, Japan. tsuyoshi@p.kanazawa-u.ac.jp
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Taniguchi
authors.forename: Hisaaki
authors.initials: H
authors.lastname: Zaimoku
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ishibashi
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010545:Peroxides / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000475:Alkenes; D006834:Hydrazines; D010545:Peroxides; D014867:Water