title: Medical therapy for systemic lupus erythematosus.
abstract: The many clinical manifestations of systemic lupus erythematosus (SLE) result in the involvement of many specialties of medicine in its treatment. An understanding of the indications, potential side-effects, and toxicity monitoring required of common agents used as medical therapy in SLE disease management is important for all providers who care for lupus patients. Pharmacological therapy is based on the type and severity of clinical manifestation and involves four primary classes of drugs: non-steroidal antiinflammatory drugs, antimalarials, corticosteroids, and immunosuppressives/cytoxics.
authors.affiliation: Department of Medicine, University of Mississippi School of Medicine, Jackson 39216, USA. jktaylor@medicine.umsmed.edu
authors.forename: Jason K
authors.initials: JK
authors.lastname: Taylor
authors.forename: Robert V
authors.initials: RV
authors.lastname: McMurray
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D000962:Antimalarials / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000962:Antimalarials; D007166:Immunosuppressive Agents