title: Direct DNA Injection (p53) into HCC Tumors.
abstract: Liver tumors, specially HCC, are among the most common malignancies in the world, and their annual world incidence is about 250,000 cases, with a male to female ratio 4:1 (1). HCC is one of the most important neoplasms in tropical and subtropical regions, particularly among the sub-Saharan African black population and ethnic Chinese (2). The prognosis is very poor, and patients with advanced tumors are unlikely to survive 3 mo (3). Most HCC cases are beyond radical resection when detected. All other forms of the currently available therapies are rarely beneficial (2).
authors.affiliation: Liver Surgery Section, Imperial College School of Medicine, Hammersmith Hospital Campus, London, UK.
authors.forename: R R
authors.initials: RR
authors.lastname: Mitry
authors.forename: N A
authors.initials: NA
authors.lastname: Habib