title: Naturally occurring anti M complicating ABO grouping.
abstract: Anti M is considered a naturally occurring antibody that is usually active at temperatures below 37°C and is thus of no clinical significance. This antibody, if present in an individual, can lead to a discrepancy between forward and reverse ABO grouping and thus creates diagnostic difficulties for blood bank staff. We report a case of a 58-year-old lady who had an unexpected reaction in reverse grouping due to anti M that posed a problem for us in the interpretation of results of her blood group. We also reviewed the literature to find out the significance of such discrepancy in blood grouping.
authors.affiliation: Royal Darwin Hospital, NT, Australia.
authors.forename: Safoorah
authors.initials: S
authors.lastname: Khalid
authors.forename: Roelyn
authors.initials: R
authors.lastname: Dantes
authors.forename: Sunu
authors.initials: S
authors.lastname: Varghese
authors.forename: Imadeddin
authors.initials: I
authors.lastname: Al Hakawati
mesh_terms: D000017:ABO Blood-Group System / Q000032:analysis*; D000906:Antibodies / Q000097:blood*; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008875:Middle Aged; D014481:United States
chemical_list: D000017:ABO Blood-Group System; D000906:Antibodies