title: Recalcitrant palmoplantar pustular psoriasis treated with etanercept.
abstract: We report a 10-year-old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children.
authors.affiliation: Department of Dermatology, La Paz University Hospital, Madrid, Spain. uxuafloristan@hotmail.com
authors.forename: Uxua
authors.initials: U
authors.lastname: Floristan
authors.forename: Rosa
authors.initials: R
authors.lastname: Feltes
authors.forename: Paloma
authors.initials: P
authors.lastname: Ramírez
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Alonso
authors.forename: Raul
authors.initials: R
authors.lastname: De Lucas
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D011565:Psoriasis / Q000188:drug therapy* / Q000532:radiotherapy*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000379:methods*
chemical_list: D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept