title: Morphologic evaluation of renal function using semi-quantitative method in primary nonproliferative glomerular diseases.
abstract: BACKGROUND
  Fibrosis is universally accepted as a poor prognostic finding in renal pathology. Semi-quantitative assessment is widely used for prognostication in pathology.
  
  
  OBJECTIVE
  We propose a semi-quantitative method to prognosticate primary nonproliferative glomerular diseases.
  
  
  METHODS
  A semi-quantitative method based on Banff schema, 97 classification has been modified to suit the requirements. Glomerular, tubulointerstitial, and vascular compartments were scored independently, and the scores were totaled to obtain total scores.
  
  
  METHODS
  Seventy-six renal biopsies were assessed by semi-quantitative scores and the individual compartmental and total scores were correlated with serum creatinine levels. Follow-up was available in 24 cases.
  
  
  METHODS
  Pearson correlation coefficient, two-tailed t test, to determine the P value.
  
  
  RESULTS
  P values were significant for the total scores as well as individual compartments. There is a linear correlation between the scores and serum creatinine levels. A total score of ≥5 was significant.
  
  
  CONCLUSIONS
  The semi-quantitative scoring system based on modified Banff schema, 1997 is useful in prognosticating renal biopsies in primary nonproliferative glomerular diseases.
authors.affiliation: Department of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad 500 082, India. arunaprayaga56@yahoo.com
authors.forename: Aruna K
authors.initials: AK
authors.lastname: Prayaga
authors.forename: S V
authors.initials: SV
authors.lastname: Anuradha
authors.forename: Y
authors.initials: Y
authors.lastname: Manjusha
authors.forename: Megha
authors.initials: M
authors.lastname: Uppin
authors.forename: Ram
authors.initials: R
authors.lastname: Rapur
authors.forename: K V
authors.initials: KV
authors.lastname: Dakshina Murthy
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology*; D007674:Kidney Diseases / Q000175:diagnosis* / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index; D055815:Young Adult