title: Antimicrobial effect of Korean propolis against the mutans streptococci isolated from Korean.
abstract: The aim of this study was to determine the optimal concentration of Korean propolis against clinical isolates of mutans streptococci (MS) from Koreans. The antimicrobial activity was evaluated using the minimum inhibitory concentration (MIC) and time-kill curves against mutans streptococci. The MIC(90) values of propolis for MS were 35 μg/ml. Propolis had a bacteriostatic effect on Streptococcus mutans ATCC 25175(T) and bactericidal effects on Streptococcus sobrinus ATCC 33478(T) at > 2 × MIC (70 μg/ml). These results suggest that the propolis can be used in the development of oral hygiene products for the prevention of dental caries.
authors.affiliation: Department of Oral Biochemistry, Chosun University, Gwangju, 501-759, Republic of Korea.
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Kim
authors.forename: Chun Sung
authors.initials: CS
authors.lastname: Kim
authors.forename: Byung-Hoon
authors.initials: BH
authors.lastname: Kim
authors.forename: Sang-Bok
authors.initials: SB
authors.lastname: Ro
authors.forename: Yun Kyong
authors.initials: YK
authors.lastname: Lim
authors.forename: Soon-Nang
authors.initials: SN
authors.lastname: Park
authors.forename: Eugene
authors.initials: E
authors.lastname: Cho
authors.forename: Engene
authors.initials: E
authors.lastname: Cho
authors.forename: Jang-Hyuk
authors.initials: JH
authors.lastname: Ko
authors.forename: Soon-Sung
authors.initials: SS
authors.lastname: Kwon
authors.forename: Yeong-Mu
authors.initials: YM
authors.lastname: Ko
authors.forename: Joong-Ki
authors.initials: JK
authors.lastname: Kook
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D044466:Asian People; D006801:Humans; D008826:Microbial Sensitivity Tests; D050296:Microbial Viability / Q000187:drug effects; D011429:Propolis / Q000494:pharmacology*; D013290:Streptococcal Infections / Q000382:microbiology*; D013295:Streptococcus mutans / Q000187:drug effects* / Q000302:isolation & purification; D016986:Streptococcus sobrinus / Q000187:drug effects* / Q000302:isolation & purification; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D011429:Propolis