title: Intrahepatic and adrenal hemorrhage as a rare cause of neonatal anemia.
abstract: Vaginal delivery of the macrosomic fetus may result in hemorrhage of intra-abdominal organs. Mostly affected organs are the liver and adrenal glands. Hemorrhage of liver is usually occurs as a subcapsular hemorrhage and it is clinically presented an abdominal mass without symptoms of anemia. But intraparenchymal hemorrhage of liver is very rare and there is no sign of abdominal mass. However, in contrast to subcapsular hemorrhage, symptoms of anemia are rapidly developed in newborns. A macrosomic newborn by vaginal delivery at term. Within 6 h after delivery, the patient showed pallor without tachycardia and hypotension. In laboratory studies, hemoglobin level failed from 14 g/dL to 10 g/dL within 6 h. Physical examination revealed no signs of abdominal mass. Intraparenchymal hemorrhage in the sixth segment of liver and right adrenal hemorrhage were detected on the ultrasonographic scan. Hepatic function tests were normal in the whole follow-up period, and hemorrhage resolved within two weeks. Following months after discharge, adrenal hemorrhage also resolved without any complication. Hepatic hemorrhages, causing hemorrhagic anemia in neonates, usually occur in subcapsular form. Intraparenchymal hepatic hemorrhage should especially be considered in those newborns, which are rapidly developed symptoms of anemia without any abdominal mass.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Erciyes University School of Medicine, Kayseri, Turkey. mustafaaliakin@hotmail.com
authors.forename: Mustafa Ali
authors.initials: MA
authors.lastname: Akin
authors.forename: Dilek
authors.initials: D
authors.lastname: Coban
authors.forename: Selim
authors.initials: S
authors.lastname: Doganay
authors.forename: Zehra
authors.initials: Z
authors.lastname: Durak
authors.forename: Selim
authors.initials: S
authors.lastname: Kurtoglu
mesh_terms: D000307:Adrenal Gland Diseases / Q000175:diagnosis / Q000209:etiology*; D000740:Anemia / Q000175:diagnosis / Q000209:etiology*; D001720:Birth Injuries / Q000175:diagnosis / Q000209:etiology*; D036861:Delivery, Obstetric / Q000009:adverse effects; D005320:Fetal Macrosomia / Q000150:complications*; D006454:Hemoglobins / Q000032:analysis; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007022:Hypotension; D007231:Infant, Newborn; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology*; D013610:Tachycardia; D014463:Ultrasonography
chemical_list: D006454:Hemoglobins