title: Sensitivity analysis of an energetic muscle model applied at whole body level in recumbent pedalling.
abstract: Musculoskeletal models are used in order to describe and analyse the mechanics of human movement. In order to get a complete evaluation of the human movement, energetic muscle models were developed and were shown to be promising.   The aim of this work is to determine the sensitivity of muscle mechanical and energetic model estimates to changes in parameters during recumbent pedalling.   Inputs of the model were electromyography and joint angles, collected experimentally on one participant. The sensitivity analysis was performed on muscle-specific tension, physiological cross-sectional area, muscle maximal force, tendon rest length and percentage of fast-twitch fibres using an integrated sensitivity ratio. Soleus, gastrocnemius, vasti, gluteus and medial hamstrings were selected for the analyses.   The energetic model was found to be always less sensitive to parameter changes than the mechanical model. Tendon slack length was found to be the most critical parameter for both energetic and mechanical models even if the effect on the energetic output was smaller than on muscle force and joint moments.
authors.affiliation: Department of Electronics, Computer Science and Systems, University of Bologna, Italy. mariacristina.bisi@unibo.it
authors.forename: M C
authors.initials: MC
authors.lastname: Bisi
authors.forename: R
authors.initials: R
authors.lastname: Stagni
authors.forename: G
authors.initials: G
authors.lastname: Gnudi
mesh_terms: D000328:Adult; D001642:Bicycling / Q000502:physiology*; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D004576:Electromyography / Q000706:statistics & numerical data; D006801:Humans; D007596:Joints / Q000502:physiology; D008297:Male; D008954:Models, Biological; D009068:Movement / Q000502:physiology; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000502:physiology*