title: Multidrug-resistant genotypes of Plasmodium falciparum, Myanmar.
abstract: We performed a molecular epidemiologic survey of mutations associated with drug-resistance genes in Plasmodium falciparum in northeastern Myanmar. In this region, 3 highly mutated drug-resistance haplotypes and 1 associated with decreased quinine susceptibility were prevalent, which suggests that parasites may be resistant to multiple commonly used antimalarial drugs.
authors.affiliation: Kunming Medical University, Yunnan, People's Republic of China.
authors.forename: Zhaoqing
authors.initials: Z
authors.lastname: Yang
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Li
authors.forename: Miao
authors.initials: M
authors.lastname: Miao
authors.forename: Zaixing
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Sun
authors.forename: Hao
authors.initials: H
authors.lastname: Meng
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Qi
authors.initials: Q
authors.lastname: Fan
authors.forename: Liwang
authors.initials: L
authors.lastname: Cui
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D018432:Drug Resistance, Multiple / Q000235:genetics*; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology; D017720:Molecular Epidemiology; D009154:Mutation; D002052:Myanmar / Q000453:epidemiology; D021261:Parasitic Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects / Q000235:genetics*; D015995:Prevalence; D015800:Protozoan Proteins / Q000737:chemistry / Q000235:genetics; D011803:Quinine / Q000494:pharmacology
chemical_list: D000962:Antimalarials; D015800:Protozoan Proteins; D011803:Quinine