title: [Detoxicating properties of remaxol with respect to multiple organ failure during severe ethanol poisoning].
abstract: Experiments on male rats showed that severe alcohol poisoning results in a multiple organ failure followed by functional impairment of heart, liver and kidney. Intensive infusion therapy with remaxol was found to significantly restore the functional activity and morphological structure of the target organs of ethanol intoxication. The results suggest that remaxol possesses antihypoxic, detoxicating, and hepatic and renal protective properties with respect to severe ethanol intoxication.
authors.forename: K V
authors.initials: KV
authors.lastname: Sivak
authors.forename: T N
authors.initials: TN
authors.lastname: Savateeva-Liubimova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Petrov
authors.forename: A L
authors.initials: AL
authors.lastname: Kovalenko
mesh_terms: D000818:Animals; D002492:Central Nervous System Depressants / Q000506:poisoning*; D000431:Ethanol / Q000506:poisoning*; D008297:Male; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000188:drug therapy*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013386:Succinates / Q000494:pharmacology*
chemical_list: D002492:Central Nervous System Depressants; C555877:Remaxol; D013386:Succinates; D000431:Ethanol