title: Linezolid in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in paediatric patients: experience of a paediatric infectious diseases unit.
abstract: Linezolid has been used in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in adults with encouraging results, however experience in children is scarce. We describe our experience with the use of linezolid as part of a multidrug regimen in the treatment of 4 patients who had persistent positive cultures, despite prolonged combined therapy.
authors.affiliation: Department of Paediatrics, Infectious Diseases, Hospital Dona Estefânia, Lisbon, Portugal. kjollerstrom@sapo.pt
authors.forename: Paula
authors.initials: P
authors.lastname: Kjöllerström
authors.forename: Maria João
authors.initials: MJ
authors.lastname: Brito
authors.forename: Catarina
authors.initials: C
authors.lastname: Gouveia
authors.forename: Gonçalo
authors.initials: G
authors.lastname: Ferreira
authors.forename: Luís
authors.initials: L
authors.lastname: Varandas
mesh_terms: D000081:Acetamides / Q000008:administration & dosage*; D000293:Adolescent; D000995:Antitubercular Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000379:methods; D054908:Extensively Drug-Resistant Tuberculosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000069349:Linezolid; D008297:Male; D023303:Oxazolidinones / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000081:Acetamides; D000995:Antitubercular Agents; D023303:Oxazolidinones; D000069349:Linezolid