title: Psychobiology and psychosocial functioning of schizoaffective disorder.
abstract: Data from neurobiologic and psychosocial outcomes research suggest that, phenomenologically, clinically, and neurobiologically, patients with schizoaffective disorder occupy an intermediate position between more severely disturbed schizophrenia patients and similarly or less severely impaired affective disorder patients. Some biologic-genetic abnormalities are shared between these disorders, while other abnormalities are specific to particular symptoms. Premorbid functioning, especially in academic areas, is better in patients with schizoaffective disorder than in those with schizophrenia, but negative symptoms and cognitive deficits are influential and should be addressed to improve psychosocial outcomes.
authors.affiliation: Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, New York, USA.
authors.forename: Christoph U
authors.initials: CU
authors.lastname: Correll
mesh_terms: D003072:Cognition Disorders / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000523:psychology; D005838:Genotype; D006801:Humans; D019964:Mood Disorders / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000523:psychology; D011379:Prognosis; D011603:Psychophysiology; D011618:Psychotic Disorders / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology* / Q000523:psychology*; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012917:Social Adjustment