title: Iron(II)-catalyzed oxidation of sp3 C-H bonds adjacent to a nitrogen atom of unprotected arylureas with tert-butyl hydroperoxide in water.
abstract: With a FeSO(4)/TBHP system in water, direct oxidation of sp(3) C-H bonds adjacent to nitrogen of arylureas to give both unprecedented tert-butoxylated and hydroxylated products 2 was revealed. Under elevated temperatures, either 2-oxo-N-arylpyrrolidine-1-carboxamides 3 or 1,3-diarylureas 4 were attained, depending on the aliphatic ring size of the arylurea substrates.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wei
authors.forename: Hongqian
authors.initials: H
authors.lastname: Ding
authors.forename: Shaoxia
authors.initials: S
authors.lastname: Lin
authors.forename: Fushun
authors.initials: F
authors.lastname: Liang