title: [Intracranial hypertension in acute liver failure and microdialysis].
abstract: Acute liver failure is a severe condition with a very unfavourable prognosis. One of the common complications and limiting factors for the outcome is the development of the intracranial hypertension. The etiology and the pathogenetic pathways leading to the development of this fatal complication of acute liver failure is still not completely understood. The aim of this review is to inform about the actual knowledge of pathogenesis of the intracranial hypertension in acute liver failure. Finally, a new method of tissue metabolism monitoring--microdialysis--is shortly discussed as a perspective method in monitoring and research on acute liver failure.
authors.affiliation: Klinika Anesteziologie, Resuscitace a Intenzivni péce 2. LF UK. jop6@centrum.cz
authors.forename: J
authors.initials: J
authors.lastname: Prazák
authors.forename: E
authors.initials: E
authors.lastname: Lásziková
authors.forename: O
authors.initials: O
authors.lastname: Ryska
authors.forename: M
authors.initials: M
authors.lastname: Ryska
mesh_terms: D000641:Ammonia / Q000378:metabolism; D001929:Brain Edema / Q000209:etiology / Q000503:physiopathology; D005973:Glutamine / Q000378:metabolism; D006801:Humans; D019586:Intracranial Hypertension / Q000209:etiology / Q000503:physiopathology*; D017114:Liver Failure, Acute / Q000150:complications* / Q000503:physiopathology; D017551:Microdialysis
chemical_list: D005973:Glutamine; D000641:Ammonia