title: Extra-axial soft tissue chordoma of wrist.
abstract: Extra-axial soft tissue chordoma is rare. We report a case of extra-axial soft tissue chordoma of the right wrist in an 87-year-old man. The tumor was large, and the cut surface showed multinodular and myxoid appearance. Microscopically, nests of epithelioid and spindle cells were observed in the myxoid matrix. Vacuolated cells were also observed. The tumor cells were diffusely positive for brachyury and cytokeratin 19 on immunohistochemistry, suggesting that the tumor was extra-axial soft tissue chordoma. Extra-axial chordoma is the same entity as chordoma periphericum (parachordoma), as proposed by Laskowski and Dabska.
authors.affiliation: Division of Diagnostic Pathology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan. hsuzuki@sap-cc.go.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Suzuki
authors.forename: Katsushige
authors.initials: K
authors.lastname: Yamashiro
authors.forename: Hiroko
authors.initials: H
authors.lastname: Takeda
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nojima
authors.forename: Masamichi
authors.initials: M
authors.lastname: Usui
mesh_terms: D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000378:metabolism; D002817:Chordoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D018572:Disease-Free Survival; D005326:Fetal Proteins / Q000378:metabolism; D006801:Humans; D053539:Keratin-19 / Q000378:metabolism; D008297:Male; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D020825:T-Box Domain Proteins / Q000378:metabolism; D014953:Wrist; D000098908:Brachyury Protein
chemical_list: D014408:Biomarkers, Tumor; D005326:Fetal Proteins; D053539:Keratin-19; D020825:T-Box Domain Proteins; D000098908:Brachyury Protein