title: Dynamics of water in concentrated solutions of amphiphiles: key roles of local structure and aggregation.
abstract: Water translational and reorientational dynamics in concentrated solutions of amphiphiles are investigated through molecular dynamics simulations and analytic modeling. We evidence the critical importance of the solute concentration in determining the magnitude of the slowdown in water dynamics compared to the bulk situation. The comparison of concentrated aqueous solutions of tetramethylurea, which tends to aggregate, and of trimethylamine N-oxide, which does not, shows the dramatic impact of solute clustering on the water dynamics. No significant decoupling of the reorientation and translation dynamics of water is observed, even at very high solute concentrations. The respective roles of energetic and topological disorders in determining the translational subdiffusive water dynamics in these confining environments are discussed. The water reorientational dynamics is shown to be quantitatively described by an extended jump model which combines two factors determined by the local structure: the transition-state excluded volume and the transition-state hydrogen-bond strength.
authors.affiliation: Ecole Normale Supérieure, Chemistry Department, UMR CNRS-ENS-UPMC 8640, Paris, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Stirnemann
authors.forename: Fabio
authors.initials: F
authors.lastname: Sterpone
authors.forename: Damien
authors.initials: D
authors.lastname: Laage