title: Effect of semen characteristics on pregnancy rate following intrauterine insemination.
abstract: OBJECTIVE
  To assess the effects of semen characteristics on the success of intrauterine insemination (IUI).
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  The Department of Obstetrics and Gynecology, Tokushima University Hospital, Japan.
  
  
  METHODS
  Between 2004 and 2008, 1,177 IUI cycles in 283 couples were studied.
  
  
  METHODS
  IUI cycles were preceded with ovarian stimulation.
  
  
  METHODS
  Clinical pregnancy.
  
  
  RESULTS
  A total of 82 clinical pregnancies were obtained (7.0% pregnancy rate per cycle, 28.9% per case). Their subsequent outcomes of pregnancies were 18 miscarriages (21.9%), 2 ectopic pregnancies (2.4%) and 60 live births (73.2%). Of the 82 clinical pregnancies, 2 were twin pregnancies (2.4%). There was no triple or higher order multiple pregnancies. At the end of the sixth cycle, 73 clinical pregnancies had been achieved (89.0%). After diagnostic laparoscopy, the pregnancy rate per cycle for patients ≤ 35 years age was 18%, which is significantly higher than that of patients >35 years of age. Pregnancies occurred up to the fifth cycle after laparoscopy. The pregnancy rate (PR) per cycle was significantly higher in cases of sperm movement rates more than 30% (PR 9.3%) and total motile sperm counts more than 10 × 10(6)/ml (PR 8.2%). A study comparing the washed and unwashed cases did not reveal any differences.
  
  
  CONCLUSIONS
  In male sub-fertility cases of sperm parameters as motility rates ≥ 30% and motile sperm concentration ≥ 10 × 10(6)/ml, IUI could be a useful option for infertility treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
authors.forename: Uranchimeg
authors.initials: U
authors.lastname: Dorjpurev
authors.forename: Akira
authors.initials: A
authors.lastname: Kuwahara
authors.forename: Yuya
authors.initials: Y
authors.lastname: Yano
authors.forename: Tomoko
authors.initials: T
authors.lastname: Taniguchi
authors.forename: Yuri
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Ayako
authors.initials: A
authors.lastname: Suto
authors.forename: Yu
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Toshiya
authors.initials: T
authors.lastname: Matsuzaki
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yasui
authors.forename: Minoru
authors.initials: M
authors.lastname: Irahara
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007246:Infertility / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D008297:Male; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D055815:Young Adult