title: Methods for Chemoprotection and Chemosensitization : MDR-1 For Chemoprotection Using Retroviruses to Modify Hematopoietic Cells and Cytosine Deaminase for Chemosensitization Using Adenoviral Vectors to Modify Epithelian Neoplastic Cells.
abstract: Surgery, radiation therapy, and chemotherapy have been applied to the curative therapy of 50% of cancer patients in the United States during the past 100 years. It is clear that the chemotherapeutic agents used to develop curative therapy for leukemias, lymphomas, gestational malignancy, and testicular cancer are not as active in the more numerous epithelial neoplasms, perhaps because of the complexity of genetic change in these latter neoplasms.
authors.affiliation: Genetic Therapy Program of the Yale Cancer Center and the Medical Oncology Section, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
authors.forename: S
authors.initials: S
authors.lastname: Shrimdkandada
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authors.initials: SQ
authors.lastname: Fu
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authors.initials: LH
authors.lastname: Yin
authors.forename: X Y
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authors.lastname: Guo
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authors.lastname: Nanakorn
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authors.lastname: Peng
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authors.lastname: Dizon
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authors.lastname: Lin
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authors.lastname: Cooperberg
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authors.initials: JH
authors.lastname: Won
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authors.initials: A
authors.lastname: Deisseroth