title: Fermentative production of L: -(+)-lactic acid by an alkaliphilic marine microorganism.
abstract: Of six strains of lactic acid-producing alkaliphilic microorganisms, Halolactibacillus halophilus was most efficient. It produced the highest concentration and yield of lactic acid, with minimal amounts of acetic and formic acid when sucrose and glucose were used as substrate. Mannose and xylose were poorly utilized. In batch fermentation at 30°C, pH 9 with 4 and 8% (w/v) sucrose, lactic acid was produced at 37.7 and 65.8 g l(-1), with yields of 95 and 83%, respectively. Likewise, when 4 and 8% (w/v) glucose were used, 33.4 and 59.6 g lactic acid l(-1) were produced with 85 and 76% yields, respectively. L: -(+)-lactic acid had an optical purity of 98.8% (from sucrose) and 98.3% (from glucose).
authors.affiliation: National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1-1-1 Higashi, Ibaraki, Tsukuba, Japan.
authors.forename: Buenaventurada P
authors.initials: BP
authors.lastname: Calabia
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tokiwa
authors.forename: Seiichi
authors.initials: S
authors.lastname: Aiba
mesh_terms: D019342:Acetic Acid / Q000378:metabolism; D001406:Bacillaceae / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D005285:Fermentation; D005561:Formates / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000378:metabolism*; D012623:Seawater / Q000382:microbiology; D013696:Temperature
chemical_list: D005561:Formates; C030544:formic acid; D019344:Lactic Acid; D019342:Acetic Acid