title: Recurrent community-acquired methicillin-resistant Staphylococcus aureus infections in an HIV-infected person.
abstract: HIV-infected persons are at heightened risk for recurrent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections, but there are limited data regarding the molecular characterization of these events. We describe an HIV-infected patient with 24 soft tissue infections and multiple colonization events. Molecular genotyping from 33 nonduplicate isolates showed all strains were USA300, Panton-Valentine leukocidin (PVL) and arginine catabolic mobile element (ACME) positive, and genetically related.
authors.affiliation: Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
authors.forename: Kartavya
authors.initials: K
authors.lastname: Vyas
authors.forename: Duane R
authors.initials: DR
authors.lastname: Hospenthal
authors.forename: Katrin
authors.initials: K
authors.lastname: Mende
authors.forename: Nancy F
authors.initials: NF
authors.lastname: Crum-Cianflone
mesh_terms: D000328:Adult; D001427:Bacterial Toxins / Q000235:genetics; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D005098:Exotoxins / Q000235:genetics; D005838:Genotype; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D020071:Interspersed Repetitive Sequences; D007956:Leukocidins / Q000235:genetics; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D058889:Molecular Typing; D012008:Recurrence; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D037521:Virulence Factors / Q000235:genetics
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors