title: Mitotic phosphorylation of nucleoporins: dismantling NPCs and beyond.
abstract: Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
authors.affiliation: Institut Jacques Monod, UMR 7592 CNRS, Université Paris Diderot, 15 rue Hélène Brion, 75205 Paris CEDEX 13, France. doye.valerie@ijm.univ-paris-diderot.fr
authors.forename: Valérie
authors.initials: V
authors.lastname: Doye