title: Quantum dots in cell biology.
abstract: Quantum dots are semiconductor nanocrystals that have broad excitation spectra, narrow emission spectra, tunable emission peaks, long fluorescence lifetimes, negligible photobleaching, and ability to be conjugated to proteins, making them excellent probes for bioimaging applications. Here the author reviews the advantages and disadvantages of using quantum dots in bioimaging applications, such as single-particle tracking and fluorescence resonance energy transfer, to study receptor-mediated transport.
authors.affiliation: Center for Cardiovascular Sciences, Albany Medical College, 47 New Scotland Avenue, Albany, NY 12208, USA. barrosm@mail.amc.edu
authors.forename: Margarida M
authors.initials: MM
authors.lastname: Barroso
mesh_terms: D000818:Animals; D001692:Biological Transport; D015374:Biosensing Techniques / Q000379:methods; D058948:Cell Tracking / Q000379:methods; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008024:Ligands; D057054:Molecular Imaging / Q000379:methods*; D045663:Quantum Dots; D011956:Receptors, Cell Surface / Q000502:physiology
chemical_list: D008024:Ligands; D011956:Receptors, Cell Surface