title: Eosinophilic esophagitis, celiac disease, and immunoglobulin E-mediated allergy in a 2-year-old child.
abstract: Celiac disease, eosinophilic esophagitis, and urticaria are 3 manifestations of food allergy with different pathogenic mechanisms. We report the case of a 2-year-old child with digestive symptoms, slow growth, and severe asthma. The results of skin prick tests were positive to several foods. Endoscopy revealed eosinophilic esophagitis and celiac disease. Treatment consisted of a gluten-free diet and a 1-month course of oral corticosteroids. Endoscopy and biopsy findings were normal at 5 years of age. A gluten-free diet is the basis of treatment of celiac disease, but the role of an elimination diet in eosinophilic esophagitis is not well established. Our patient also developed urticaria when exposed to milk and egg.We present, to our knowledge, the first report of a patient with celiac disease, eosinophilic esophagitis, and immediate-type immunoglobulin E-mediated food allergy.
authors.affiliation: Department of Allergology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. ssanchez@salud.madrid.org
authors.forename: S
authors.initials: S
authors.lastname: Sánchez-García
authors.forename: M D
authors.initials: MD
authors.lastname: Ibáñez
authors.forename: M J
authors.initials: MJ
authors.lastname: Martinez-Gómez
authors.forename: C
authors.initials: C
authors.lastname: Escudero
authors.forename: A
authors.initials: A
authors.lastname: Vereda
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Rodríguez
authors.forename: P
authors.initials: P
authors.lastname: Rodríguez del Río
mesh_terms: D000818:Animals; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis* / Q000178:diet therapy; D002675:Child, Preschool; D055050:Diet, Gluten-Free; D004529:Egg White / Q000009:adverse effects; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis* / Q000178:diet therapy; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis* / Q000178:diet therapy; D005983:Glutens / Q000009:adverse effects; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008892:Milk / Q000009:adverse effects; D016896:Treatment Outcome; D014581:Urticaria / Q000150:complications / Q000178:diet therapy / Q000209:etiology / Q000276:immunology
chemical_list: D007073:Immunoglobulin E; D005983:Glutens