title: Comparison of computed tomography scout based reference point localization to conventional film and axial computed tomography.
abstract: Identification of source positions after implantation is an important step in brachytherapy planning. Reconstruction is traditionally performed from films taken by conventional simulators, but these are gradually being replaced in the clinic by computed tomography (CT) simulators. The present study explored the use of a scout image-based reconstruction algorithm that replaces the use of traditional film, while exhibiting low sensitivity to metal-induced artifacts that can appear in 3D CT methods. In addition, the accuracy of an in-house graphical software implementation of scout-based reconstruction was compared with seed location reconstructions for 2 phantoms by conventional simulator and CT measurements. One phantom was constructed using a planar fixed grid of 1.5-mm diameter ball bearings (BBs) with 40-mm spacing. The second was a Fletcher-Suit applicator embedded in Styrofoam (Dow Chemical Co., Midland, MI) with one 3.2-mm-diameter BB inserted into each of 6 surrounding holes. Conventional simulator, kilovoltage CT (kVCT), megavoltage CT, and scout-based methods were evaluated by their ability to calculate the distance between seeds (40 mm for the fixed grid, 30-120 mm in Fletcher-Suit). All methods were able to reconstruct the fixed grid distances with an average deviation of <1%. The worst single deviations (approximately 6%) were exhibited in the 2 volumetric CT methods. In the Fletcher-Suit phantom, the intermodality agreement was within approximately 3%, with the conventional sim measuring marginally larger distances, with kVCT the smallest. All of the established reconstruction methods exhibited similar abilities to detect the distances between BBs. The 3D CT-based methods, with lower axial resolution, showed more variation, particularly with the smaller BBs. With a software implementation, scout-based reconstruction is an appealing approach because it simplifies data acquisition over film-based reconstruction without requiring any specialized equipment and does not carry risk of misreads caused by artifacts.
authors.affiliation: Department of Radiation Oncology, Rush University Medical Center, Chicago, IL 60612, USA.
authors.forename: Lan
authors.initials: L
authors.lastname: Jiang
authors.forename: Alistair
authors.initials: A
authors.lastname: Templeton
authors.forename: Julius
authors.initials: J
authors.lastname: Turian
authors.forename: Michael
authors.initials: M
authors.lastname: Kirk
authors.forename: Thomas
authors.initials: T
authors.lastname: Zusag
authors.forename: James C H
authors.initials: JC
authors.lastname: Chu
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001918:Brachytherapy / Q000379:methods*; D003198:Computer Simulation; D004867:Equipment Design; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008670:Metals; D019047:Phantoms, Imaging; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D011881:Radiotherapy, Computer-Assisted / Q000379:methods*; D012984:Software; D036542:Tomography, Spiral Computed / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014962:X-Ray Film
chemical_list: D008670:Metals