title: Hyperthyroidism in a case of Down syndrome.
abstract: An 18 years old mentally retarded male, with morphologic features suggestive of Down syndrome was admitted with fever since 3 weeks. Karyotyping proved trisomy 21. Prominent thyroid swelling with resting tachycardia and hyper-irritability was present. He was found to have multiple renal abscesses and was treated with antibiotics. Thyroid function tests revealed hyperthyroidism which responded to anti-thyroid drugs. So, we report this case of Down syndrome with hyperthyroidism which is a rare association.
authors.affiliation: Department of Medicine, TNMC and BYL Nair Ch Hospital, Mumbai 400008.
authors.forename: V A
authors.initials: VA
authors.lastname: Londhey
authors.forename: G C
authors.initials: GC
authors.lastname: Rajadhyaksh
authors.forename: K S
authors.initials: KS
authors.lastname: Barhate
authors.forename: A V
authors.initials: AV
authors.lastname: More
authors.forename: C R
authors.initials: CR
authors.lastname: Dedhia
mesh_terms: D000293:Adolescent; D002231:Carbimazole / Q000627:therapeutic use*; D004314:Down Syndrome / Q000150:complications*; D004452:Echocardiography; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011433:Propranolol / Q000627:therapeutic use*; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D016896:Treatment Outcome
chemical_list: D002231:Carbimazole; D011433:Propranolol