title: Reevaluating brain networks activated during mental imagery of finger movements using probabilistic Tensorial Independent Component Analysis (TICA).
abstract: The cerebral and cerebellar networks involved in execution and mental imagery of the same sequential finger movements performed with the non-dominant hand were assessed by 3T functional magnetic resonance imaging using multivariate model-free analysis. Eight right-handed healthy volunteers successively performed execution and mental imagery tasks (sequential thumb to fingers opposition). The same data were analyzed by using (1) the linear General Model (p < 0.05 corrected), and (2) probabilistic tensorial independent component analysis (TICA). TICA confirmed that overt movement execution and motor imagery share a common network mainly including: premotor, parietal, insular, temporal, cerebellar cortices and putamen. Motor imagery specifically and bilaterally recruited frontopolar, prefrontal, cingulate, medial insula, neocerebellar cortices and precuneus. Non-dominant hand movements induced bilateral brain and cerebellar activation. In comparison with GLM, TICA identified a more widespread and bilateral network especially during motor imagery. TICA revealed that motor imagery also recruits frontopolar precuneal and occipital cortices, rostral M1/S1 corresponding to the hand somatotopic representation, thalamus and cerebellar lobule VIII. TICA also showed concomitant activation of (1) a cerebello-thalamo-cortical network during motor execution, and (2) a control executive network during imagination. TICA therefore allows precise identification of the brain networks collaborating in the same performance. TICA constitutes a valuable tool to assess and improve detection of brain networks engaged in mental imagery in comparison with GLM.
authors.affiliation: Service de Neurologie et Neurorevalidation, Hôpital Erasme, ULB, Brussels, Belgium.
authors.forename: Chloé
authors.initials: C
authors.lastname: Sauvage
authors.forename: S
authors.initials: S
authors.lastname: Poirriez
authors.forename: Mario
authors.initials: M
authors.lastname: Manto
authors.forename: Patrice
authors.initials: P
authors.lastname: Jissendi
authors.forename: Christophe
authors.initials: C
authors.lastname: Habas
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D002531:Cerebellum / Q000502:physiology; D005260:Female; D005385:Fingers / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007092:Imagination / Q000502:physiology*; D016014:Linear Models; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D015233:Models, Statistical; D009068:Movement; D015999:Multivariate Analysis; D009415:Nerve Net / Q000502:physiology*; D055815:Young Adult