title: [Aggregation, deformation and morphology of erythrocytes in patients with ischemic heart disease after injection of ioversol, iodixanol and gadobutrol].
abstract: In patients with ischemic heart disease, the administration of contrast agents iodixanol, ioversol and gadobutrol improves (due to the effect of dilution) the aggregation of erythrocytes in vivo, but does not change their deformation ability and the percentage of different morphological forms of erythrocytes (discocytes and ehinocytes) in the blood. The effect of gadobutrol on the aggregation of erythrocytes is characterized by more expressed antiaggregant effect due special molecular properties of this drug.
authors.forename: O A
authors.initials: OA
authors.lastname: Kiseleva
authors.forename: A N
authors.initials: AN
authors.lastname: Usenko
authors.forename: N L
authors.initials: NL
authors.lastname: Shimanovskiĭ
authors.forename: N N
authors.initials: NN
authors.lastname: Firsov
mesh_terms: D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage*; D004903:Erythrocyte Aggregation / Q000187:drug effects*; D004907:Erythrocyte Deformability / Q000187:drug effects*; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000000981:diagnostic imaging; D009942:Organometallic Compounds / Q000008:administration & dosage*; D011859:Radiography; D014283:Triiodobenzoic Acids / Q000008:administration & dosage*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D014283:Triiodobenzoic Acids; C090600:gadobutrol; C044834:iodixanol; C054871:ioversol