title: Medication use in patients with migraine and medication-overuse headache: the role of problem-solving and attitudes about pain medication.
abstract: Excessive medication intake is a risk factor for the development of medication-overuse headache (MOH), a condition characterized by an increase of headache frequency to a daily or near-daily pattern. As yet, it is largely unknown why some patients overuse medication. In this study, we examined to what extent attitudes about pain medication, especially perceived need and concerns, and problem-solving are related to MOH. Patients with migraine (n=133) and MOH with a history of migraine (n=42) were recruited from a tertiary headache referral center and completed questionnaires measuring problem-solving and attitudes about pain medication. A problem-solving mode aimed at solving pain was associated with a higher need for and concerns about medication intake. Interestingly, in a model accounting for demographic factors and pain intensity, attempts to control pain, need for medication, and concerns about scrutiny by others because of medication intake all had a unique value in accounting for MOH. Results are discussed in terms of how repeated attempts to solve pain may trigger overuse of medication, even in the presence of clear negative consequences. Repeated attempts at solving pain may increase the need for analgesic medication, despite obvious costs. This mechanism might contribute to the problem of medication-overuse headache.
authors.affiliation: Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium Department of Neurology, Ghent University Hospital, Ghent, Belgium.
authors.forename: Emelien
authors.initials: E
authors.lastname: Lauwerier
authors.forename: Koen
authors.initials: K
authors.lastname: Paemeleire
authors.forename: Stefaan
authors.initials: S
authors.lastname: Van Damme
authors.forename: Liesbet
authors.initials: L
authors.lastname: Goubert
authors.forename: Geert
authors.initials: G
authors.lastname: Crombez
mesh_terms: D000700:Analgesics / Q000009:adverse effects*; D001290:Attitude; D016009:Chi-Square Distribution; D004185:Disability Evaluation; D006261:Headache / Q000139:chemically induced* / Q000523:psychology*; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000188:drug therapy*; D009483:Neuropsychological Tests; D010147:Pain Measurement; D011340:Problem Solving / Q000187:drug effects*; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires
chemical_list: D000700:Analgesics