title: In vitro corrosion study of different TiO2 nanotube layers on titanium in solution with serum proteins.
abstract: Titanium oxide nanotubes prepared by anodization have received considerable attention in the biomaterials domain. The objective of this study was to demonstrate the electrochemical behavior of different diameter TiO(2) nanotube layers on titanium in phosphate buffered saline (PBS) and Dulbecco's minimum essential medium+10% fetal calf serum (D-FCS) using open circuit potentials (OCP), electrical impedance spectroscopy (EIS), and a potentiodynamic polarization test. The results showed that the nanotubes had higher OCP, higher resistance of the inter barrier layer (R(b)), and lower I(pass) in the two test solutions compared to the smooth Ti, especially the 30 nm diameter nanotubes. The corrosion resistance of the nanotubes in D-FCS was higher than in PBS because of protein adsorption from the D-FCS solution as suggested by scanning electron microscope (SEM) images. In addition, protein aggregates of 30 nm diameter nanotubes caused the model of EIS spectra to transform from two-layer to three-layer. The corrosion behavior of the nanotubes for use as a dental implant material is discussed.
authors.affiliation: Department of Prosthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Research Institute of Stomatology, 639 Zhizaoju Road, Huangpu District, Shanghai 200011, China.
authors.forename: Wei-qiang
authors.initials: WQ
authors.lastname: Yu
authors.forename: Jing
authors.initials: J
authors.lastname: Qiu
authors.forename: Fu-qiang
authors.initials: FQ
authors.lastname: Zhang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001798:Blood Proteins / Q000737:chemistry*; D003343:Corrosion; D008855:Microscopy, Electron, Scanning; D043942:Nanotubes / Q000737:chemistry*; D010316:Particle Size; D012996:Solutions / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D001798:Blood Proteins; D012996:Solutions; C009495:titanium dioxide; D014025:Titanium