title: [Two elderly case reports of renal excretion type drug poisoning caused by dehydration that was due to poor eating in home care].
abstract: The elderly patients are susceptible to acute renal failure due to dehydration or infection. Therefore, the drug should be administered with caution. We report two cases of acute renal failure from dehydration that led to a subsequent drug poisoning. Case 1: An 85-year-old woman with a history of colorectal cancer surgery was admitted to our emergency department for appetite loss and weakness. Because she was given a normal amount of drugs under the condition of poor oral intake, she was hospitalized by digitalism. Case 2: A 72-year-old woman was admitted to our emergency department for disturbance of consciousness and appetite loss. The medication given by a staff in geriatric health services facility appeared to have caused a pilsicainide poisoning. As the elderly patients were given a normal amount of drugs under the poor oral intake condition, blood levels of renal excretion type drug had increased in both cases. Medication management for the elderly should be comprehensively considered the background of the individual.
authors.affiliation: Nutrition Support Team(NST), Minoh City Hospital.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ibata
authors.forename: Hiromi
authors.initials: H
authors.lastname: Hinokiyama
authors.forename: Chisako
authors.initials: C
authors.lastname: Nakashita
authors.forename: Saori
authors.initials: S
authors.lastname: Mito
authors.forename: Seiko
authors.initials: S
authors.lastname: Doi
authors.forename: Satomi
authors.initials: S
authors.lastname: Shiki
authors.forename: Akiko
authors.initials: A
authors.lastname: Hata
authors.forename: Miyuki
authors.initials: M
authors.lastname: Sato
authors.forename: Ryutaro
authors.initials: R
authors.lastname: Komuro
authors.forename: Hohei
authors.initials: H
authors.lastname: Iijima
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000209:etiology; D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000506:poisoning* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D003681:Dehydration / Q000150:complications*; D001068:Feeding and Eating Disorders / Q000150:complications*; D005260:Female; D006699:Home Care Services; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives* / Q000506:poisoning / Q000627:therapeutic use; D010166:Palliative Care; D012004:Rectal Neoplasms / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; C042288:pilsicainide