title: Biologic and clinical features of benign solid and cystic lesions of the liver.
abstract: The widespread use of imaging analyses, either routinely or to evaluate symptomatic patients, has increased the detection of liver lesions (tumors and cysts) in otherwise healthy individuals. Although some of these incidentally discovered masses are malignant, most are benign and must be included in the differential diagnosis. The management of benign hepatic tumors ranges from conservative to aggressive, depending on the nature of the lesions. New imaging modalities, increased experience of radiologists, improved definition of radiologic characteristics, and a better understanding of the clinical features of these lesions have increased the accuracy of diagnoses and reduced the need for invasive diagnostic tests. These advances have led to constant adjustments in management approaches to benign hepatic lesions. We review the biologic and clinical features of some common hepatic lesions, to guide diagnosis and management strategies.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Oren
authors.initials: O
authors.lastname: Shaked
authors.forename: Evan S
authors.initials: ES
authors.lastname: Siegelman
authors.forename: Kim
authors.initials: K
authors.lastname: Olthoff
authors.forename: K Rajender
authors.initials: KR
authors.lastname: Reddy
mesh_terms: D003560:Cysts / Q000175:diagnosis* / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology*