title: Percutaneous cannulation for extracorporeal life support.
abstract: BACKGROUND
  Extracorporeal life-support systems are valuable tools to treat patients with acute cardiopulmonary failure in intensive care facilities, and are highly suitable for the interhospital transfer of critically ill patients to specialized centers. This article reviews the cannulation strategies and associated vascular complications in our institution.
  
  
  METHODS
  Between January 2004 and December 2009, 464 extracorporeal life-support systems were implanted via percutaneous cannulation at our institution. The type and incidence of adverse events related to the percutaneous access to femoral, subclavian vessels and the jugular vein were retrospectively analyzed. The primary focus was on bleeding and limb ischemia.
  
  
  RESULTS
  464 patients (340 male, 124 female) with isolated pulmonary or combined cardiopulmonary failure were connected to extracorporeal gas exchange systems. Most patients (n = 196) were connected to a PECLA system; 158 patients to a veno-arterial ECMO. Use of a veno-venous ECMO system was necessary in 110 cases. Thirty-two patients (6.9 %) suffered bleeding complications after cannula insertion, predominantly after PECLA placement (3.9 %). After implantation, limb ischemia developed in 15 cases (3.2 %), mostly in the veno-arterial ECMO group (n = 13). Demographic data and cannula size show no significant difference between patient groups with and without ischemic complications ( P = 0.57). A prophylactic fasciotomy was performed in the 15 cases with limb ischemia. Survival was independent of ischemic (leg) complications.
  
  
  CONCLUSIONS
  With proper vessel visualization, exposure and cannulation, and accurate cannula placement, optimal flows and minimal complication rates can be achieved, rendering percutaneous extracorporeal life support a safe procedure.
authors.affiliation: Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany. patrycja.ganslmeier@klinik.uni-regensburg.de
authors.forename: P
authors.initials: P
authors.lastname: Ganslmeier
authors.forename: A
authors.initials: A
authors.lastname: Philipp
authors.forename: L
authors.initials: L
authors.lastname: Rupprecht
authors.forename: C
authors.initials: C
authors.lastname: Diez
authors.forename: M
authors.initials: M
authors.lastname: Arlt
authors.forename: T
authors.initials: T
authors.lastname: Mueller
authors.forename: K
authors.initials: K
authors.lastname: Pfister
authors.forename: M
authors.initials: M
authors.lastname: Hilker
authors.forename: C
authors.initials: C
authors.lastname: Schmid
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002406:Catheterization, Peripheral / Q000009:adverse effects / Q000401:mortality; D016009:Chi-Square Distribution; D004867:Equipment Design; D005112:Extracorporeal Circulation / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D005121:Extremities / Q000098:blood supply; D005260:Female; D005858:Germany; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000601:surgery; D008020:Life Support Care / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult