title: Cell cycle: who turns the crank?
abstract: The oscillating activity of a single CDK-cyclin fusion protein can drive the orderly progression of yeast cells through DNA replication, mitosis and cell division.
authors.affiliation: Department of Biological Sciences, Virginia Polytechnic Institute & State University, Blacksburg, VA 24060, USA. tyson@vt.edu
authors.forename: John J
authors.initials: JJ
authors.lastname: Tyson
authors.forename: Bela
authors.initials: B
authors.lastname: Novak
mesh_terms: D016203:CDC2 Protein Kinase / Q000378:metabolism*; D002453:Cell Cycle / Q000502:physiology*; D019926:Cyclin B / Q000378:metabolism*; D016213:Cyclins / Q000378:metabolism*; D008954:Models, Biological; D010766:Phosphorylation; D011993:Recombinant Fusion Proteins / Q000378:metabolism*; D012568:Schizosaccharomyces; D029702:Schizosaccharomyces pombe Proteins / Q000378:metabolism*
chemical_list: C498823:Cdc13 protein, S pombe; D019926:Cyclin B; D016213:Cyclins; D011993:Recombinant Fusion Proteins; D029702:Schizosaccharomyces pombe Proteins; D016203:CDC2 Protein Kinase; C469447:cdc2 protein, S pombe