title: From symmetric glycerol derivatives to dissymmetric chlorohydrins.
abstract: The anticipated worldwide increase in biodiesel production will result in an accumulation of glycerol for which there are insufficient conventional uses. The surplus of this by-product has increased rapidly during the last decade, prompting a search for new glycerol applications. We describe here the synthesis of dissymmetric chlorohydrin esters from symmetric 1,3-dichloro-2-propyl esters obtained from glycerol. We studied the influence of two solvents: 1,4-dioxane and 1-butanol and two bases: sodium carbonate and 1-butylimidazole, on the synthesis of dissymmetric chlorohydrin esters. In addition, we studied the influence of other bases (potassium and lithium carbonates) in the reaction using 1,4-dioxane as the solvent. The highest yield was obtained using 1,4-dioxane and sodium carbonate.
authors.affiliation: Department of Chemistry, Lleida University, Alcalde Rovira Roure 191, 25198 Lleida, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Solarte
authors.forename: Marc
authors.initials: M
authors.lastname: Escribà
authors.forename: Jordi
authors.initials: J
authors.lastname: Eras
authors.forename: Gemma
authors.initials: G
authors.lastname: Villorbina
authors.forename: Ramon
authors.initials: R
authors.lastname: Canela
authors.forename: Mercè
authors.initials: M
authors.lastname: Balcells
mesh_terms: D002728:Chlorohydrins / Q000737:chemistry*; D005990:Glycerol / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D002728:Chlorohydrins; D005990:Glycerol