title: Microbiological profile of haematogenous osteoarticular infections in children.
abstract: BACKGROUND
  Staphylococcus aureus, Kingella kingae and β-hemolytic streptococcus are presently the most frequently identified bacteria in child haematogenous osteoarticular infection.
  
  
  OBJECTIVE
  To determine the microbiological profile (bacteria and antibiotic susceptibility) of osteoarticular infections in a paediatric hospital, so as to adapt treatment protocols to the ecology of the bacteria isolated.
  
  
  METHODS
  Prospective descriptive study, including children admitted for acute osteomyelitis or septic arthritis. A series of blood cultures was performed systematically on admission. In case of surgery, local samples were taken for bacteriology. Antibiotherapy was initiated and subsequently adapted to the bacteriological findings.
  
  
  RESULTS
  One hundred and six children were included. Thirty-five were under (Group 1) and 71 over 3 years of age (Group 2). Ninety-five underwent surgery. Peroperative samples were positive in 61 cases and blood culture in 23. Bacteria were isolated in 22 patients in G1. Extended-spectrum β-lactamase-producing Klebsiella pneumoniae was isolated in five neonates who had passed through intensive care. Staphylococcus aureus was the most frequently isolated bacterium in G2 (n=40), and was methicillin-resistant (MRSA) in six children.
  
  
  CONCLUSIONS
  Methicillin-susceptible Staphylococcus aureus was the most frequently isolated microorganism. Other than neonates who had passed through intensive care and the six patients with community-acquired MRSA infection, all isolated bacteria were susceptible to second-generation cephalosporins.
  
  
  METHODS
  II, prospective descriptive prognostic study.
authors.affiliation: Department of anaesthesia and intensive care, Children's Hospital, Bab Saadoun, 1006 Tunis, Tunisia. mehditrifa@yahoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Trifa
authors.forename: S
authors.initials: S
authors.lastname: Bouchoucha
authors.forename: H
authors.initials: H
authors.lastname: Smaoui
authors.forename: M
authors.initials: M
authors.lastname: Frikha
authors.forename: S
authors.initials: S
authors.lastname: Ben Marzouk
authors.forename: M
authors.initials: M
authors.lastname: Ben Ghachem
authors.forename: A
authors.initials: A
authors.lastname: Kechrid
authors.forename: A
authors.initials: A
authors.lastname: Fekih Hassen
authors.forename: S
authors.initials: S
authors.lastname: Ben Khalifa
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007710:Klebsiella Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents