title: Synthesis of chiral N-heterocyclic carbene ligands with rigid backbones and application to the palladium-catalyzed enantioselective intramolecular α-arylation of amides.
abstract: Chiral N-heterocyclic carbene (NHC) ligands having a 2,2'-bisquinoline-based C(2) symmetric skeleton were developed. The ligands exhibited good enantioselectivity in palladium-catalyzed intramolecular α-arylation of amides to give 3,3-disubsituted oxindoles.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan.
authors.forename: Lantao
authors.initials: L
authors.lastname: Liu
authors.forename: Naoki
authors.initials: N
authors.lastname: Ishida
authors.forename: Shinji
authors.initials: S
authors.lastname: Ashida
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami