title: Molecular epidemiology of Mycobacterium tuberculosis, Buenos Aires, Argentina.
abstract: To analyze the molecular epidemiology of Mycobacterium tuberculosis strains at a hospital in Buenos Aires, Argentina, and mutations related to multidrug-resistant and extensively drug-resistant tuberculosis, we conducted a prospective case-control study. Our findings reinforce the value of incorporating already standardized molecular methods for rapidly detecting resistance.
authors.affiliation: Hospital de Infecciosas Francisco Javier Muniz, Buenos Aires, Argentina. gonzaloximena@hotmail.com
authors.forename: Ximena
authors.initials: X
authors.lastname: Gonzalo
authors.forename: Marta
authors.initials: M
authors.lastname: Ambroggi
authors.forename: Ezequiel
authors.initials: E
authors.lastname: Cordova
authors.forename: Tim
authors.initials: T
authors.lastname: Brown
authors.forename: Susana
authors.initials: S
authors.lastname: Poggi
authors.forename: Francis
authors.initials: F
authors.lastname: Drobniewski
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D001118:Argentina / Q000453:epidemiology; D001426:Bacterial Proteins / Q000235:genetics; D016022:Case-Control Studies; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D054908:Extensively Drug-Resistant Tuberculosis / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D009154:Mutation; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D011446:Prospective Studies; D014376:Tuberculosis / Q000453:epidemiology* / Q000382:microbiology; D018088:Tuberculosis, Multidrug-Resistant / Q000453:epidemiology* / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents; D001426:Bacterial Proteins