title: Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.
authors.affiliation: Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke Québec, J1H5N4, Canada. eric.marsault@usherbrooke.ca
authors.forename: Eric
authors.initials: E
authors.lastname: Marsault
authors.forename: Mark L
authors.initials: ML
authors.lastname: Peterson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003500:Cyclization; D055808:Drug Discovery / Q000379:methods*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011485:Protein Binding / Q000187:drug effects; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D047028:Macrocyclic Compounds; D043562:Receptors, G-Protein-Coupled