title: An effective DNA-based electrochemical switch for reagentless detection of living cells.
abstract: A novel switch-cytosensing strategy has been designed, which is based on the changes of electron transfer efficiency between ferrocene at the end of DNA and the electrode surface before and after cell transfection. This strategy provided a general and convenient method to fabricate efficient electrochemical cell sensors.
authors.affiliation: Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Zhou
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Chen
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002460:Cell Line; D002470:Cell Survival; D018914:Cells, Immobilized / Q000166:cytology / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D015342:DNA Probes / Q000737:chemistry / Q000378:metabolism; D004563:Electrochemistry; D004566:Electrodes; D005296:Ferrous Compounds / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D000075163:Metallocenes; D014162:Transfection
chemical_list: D015342:DNA Probes; D005296:Ferrous Compounds; D000075163:Metallocenes; D006046:Gold; D004247:DNA; C004998:ferrocene