title: Encapsulated enhanced green fluorescence protein in silica nanoparticle for cellular imaging.
abstract: The enhanced green fluorescence protein (EGFP) is efficiently encapsulated in silica nanoparticle by multiple covalent bonds. The silica encapsulation greatly increases EGFP's fluorescence intensity and stabilities against protease, denaturant and heat, making it a potential fluorescence probe for cellular imaging.
authors.affiliation: Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai, 200444, China.
authors.forename: Zhengwei
authors.initials: Z
authors.lastname: Cai
authors.forename: Zhangmei
authors.initials: Z
authors.lastname: Ye
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Yang
authors.forename: Yanli
authors.initials: Y
authors.lastname: Chang
authors.forename: Haifang
authors.initials: H
authors.lastname: Wang
authors.forename: Yuanfang
authors.initials: Y
authors.lastname: Liu
authors.forename: Aoneng
authors.initials: A
authors.lastname: Cao
mesh_terms: D002478:Cells, Cultured / Q000166:cytology*; D004337:Drug Carriers / Q000737:chemistry*; D049452:Green Fluorescent Proteins / Q000032:analysis* / Q000737:chemistry*; D008856:Microscopy, Fluorescence / Q000379:methods*; D053769:Nanocapsules / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D053769:Nanocapsules; D049452:Green Fluorescent Proteins; D012822:Silicon Dioxide