title: Stereo- and regioselective glycosylation of 4-deoxy-ε-rhodomycinone.
abstract: A method for the glycosylation of anthracyclines featuring benzoylated imidate donors has been developed and utilized in the synthesis of glycosylated 4-deoxy-ε-rhodomycinone derivatives. Due to its high efficiency, regioselectivity, stereoselectivity, and operational simplicity, the method should prove valuable to researchers working with glycosylation of tetracyclic compounds.
authors.affiliation: Laboratory of Organic Chemistry, Åbo Akademi University, FI-20500 Åbo, Finland.
authors.forename: Filip S
authors.initials: FS
authors.lastname: Ekholm
authors.forename: Lucas
authors.initials: L
authors.lastname: Lagerquist
authors.forename: Reko
authors.initials: R
authors.lastname: Leino
mesh_terms: D018943:Anthracyclines / Q000737:chemistry; D006027:Glycosides / Q000138:chemical synthesis / Q000737:chemistry; D006031:Glycosylation; D015394:Molecular Structure
chemical_list: D018943:Anthracyclines; D006027:Glycosides; C015490:rhodomycinone