title: Long-term follow-up of living-donor single-lobe lung transplantation for bronchiolitis obliterans in a four-year-old male: improvement of over-sized lung allograft.
abstract: We report a long-term outcome of extremely oversized lung allograft. A left lower lobe transplantation from an adult donor was performed on a four-year-old recipient after left pneumonectomy. Lobar lung allograft volume was calculated to be approximately 180% of the recipient's predicted left thoracic capacity. Accordingly, the lung allograft was compressed to 47% of its original size immediately after transplantation. Initial postoperative functional recovery of the allograft was excellent despite this severe compression. As the patient grew physically, both his forced expiratory volume in 1 s (FEV(1)) and his left lung volume increased slowly but steadily during an observation period of two years and four months after transplantation.
authors.affiliation: Department of Thoracic Surgery, Fukuoka University School of Medicine, 45-1, 7-chome, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. hiratsuk@fukuoka-u.ac.jp
authors.forename: Masafumi
authors.initials: M
authors.lastname: Hiratsuka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Takao
authors.initials: T
authors.lastname: Higuchi
authors.forename: Akinori
authors.initials: A
authors.lastname: Iwasaki
mesh_terms: D001989:Bronchiolitis Obliterans / Q000601:surgery*; D002675:Child, Preschool; D005541:Forced Expiratory Volume; D006801:Humans; D019520:Living Donors; D008168:Lung / Q000000981:diagnostic imaging / Q000601:surgery*; D016040:Lung Transplantation; D008176:Lung Volume Measurements; D008297:Male; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome