title: [Risk of pneumonia with inhaled corticosteroids for stable chronic obstructive pulmonary disease patients].
abstract: OBJECTIVE
  Treatment with inhaled steroids is related to pneumonia and acute respiratory infection. The aim of this review is to quantify the effect inhaled steroids in pneumonia in stable chronic obstructive pulmonary disease (COPD) patients.
  
  
  METHODS
  We performed a systematic review of the systematic reviews that have studied inhaled corticosteroids in stable COPD patients.
  
  
  RESULTS
  Inhaled steroid therapy in patients with clinically stable COPD causes an increase in the number of pneumonia. The NNTH of the analysed systematic reviews ranged from 12 subjects exposed to more than three years, to 80 subjects with one year follow up. Budesonide did not show this side effect.
  
  
  CONCLUSIONS
  It would be advisable to inform patients about the risk/benefit of these therapies.
authors.affiliation: Unidad de Hospitalización a Domicilio, CASP, Hospital Universitario La Fe, Valencia, España. vicenteruizgarcia@gmail.com
authors.forename: Vicente
authors.initials: V
authors.lastname: Ruiz García
authors.forename: Luis
authors.initials: L
authors.lastname: Compte Torrero
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000627:therapeutic use; D019819:Budesonide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D004198:Disease Susceptibility; D004338:Drug Combinations; D019317:Evidence-Based Medicine; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D015201:Meta-Analysis as Topic; D011014:Pneumonia / Q000209:etiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000188:drug therapy*; D012306:Risk
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D004338:Drug Combinations; D019819:Budesonide