title: Ablative therapies for Barrett's esophagus.
abstract: Barrett's esophagus has gained increased clinical attention because of its association with esophageal adenocarcinoma, a cancer with increasing incidence and poor survival rates. The goals of ablating Barrett's esophagus are to decrease esophageal cancer rates and to improve overall survival and quality of life. Different techniques have been developed and tested for their effectiveness eradicating Barrett's epithelium. This review assesses the literature associated with different ablative techniques. The safety and efficacy of different techniques are discussed. This review concludes with recommendations for the clinician, including specific strategies for patient care decisions for patients with Barrett's esophagus with varying degrees of dysplasia.
authors.affiliation: Division of Gastroenterology, Institute for Genome Science and Policy, Duke University, Box 3913 DUMC, Durham, NC 27710, USA. katherine.garman@duke.edu
authors.forename: Katherine S
authors.initials: KS
authors.lastname: Garman
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Shaheen
mesh_terms: D000230:Adenocarcinoma / Q000517:prevention & control*; D057908:Argon Plasma Coagulation / Q000009:adverse effects; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology / Q000628:therapy*; D017115:Catheter Ablation / Q000009:adverse effects; D017679:Cryotherapy / Q000009:adverse effects; D004938:Esophageal Neoplasms / Q000517:prevention & control*; D004947:Esophagus / Q000601:surgery; D006801:Humans; D009092:Mucous Membrane / Q000601:surgery; D010778:Photochemotherapy / Q000009:adverse effects