title: Detection of Penicillin Resistance in Streptococcus pneumoniae by a Seminested PCR Strategy.
abstract: The first appearance of clinically significant penicillin-resistant Streptococcus pneumoniae (pneumococcus) occurred in 1967 in Australia (1) and penicillin resistant and multiresistant pneumococci have subsequently spread globally and reached high prevalence in many countries (2).
authors.affiliation: South African Institute of Medical Research, Johannesburg, South Africa.
authors.forename: M
authors.initials: M
authors.lastname: Plessis
authors.forename: A M
authors.initials: AM
authors.lastname: Smith
authors.forename: K P
authors.initials: KP
authors.lastname: Klugman