title: [Epidemiological and clinical significance of hepatitis B and C marker detection in blood of patients and donors].
abstract: During the assessment of 118 299 patients from hospital n. a. A.A.Vishnevskiy (2001-2005) anti-HCV was found out in 3.6%, HbsAg in 1.94%. By comparison with data of 1992-1994 (hospital n. a. N.N.Burdenko) the indices of disclosure of anti-HCV in in-patients fell 2 times, HbsAg 6.4 times. During this period, diverse changes of frequency of detection of markers in blood-donors took place: HbsAg--reduction, anti-HCV-elevation. During 2001-2005 reduction of frequency of detection of anti-HCV was noted in in-patients and blood donors, but reduction of frequency of detection of HbsAg only in blood donors. The frequency of detection of hepatitis C, B markers in blood donors during the last 10-15 years is correlated with the incidence of virus cirrhosis. Dynamic changes or stability of frequency of detection of hepatitis C, B markers in blood donors and in-patients during current period is correlated with the score of virus cirrhosis mortality.
authors.forename: A I
authors.initials: AI
authors.lastname: Pavlov
authors.forename: A I
authors.initials: AI
authors.lastname: Khazanov
authors.forename: S A
authors.initials: SA
authors.lastname: Beliakin
authors.forename: S V
authors.initials: SV
authors.lastname: Pliusnin
mesh_terms: D015415:Biomarkers / Q000097:blood; D001782:Blood Donors; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology* / Q000401:mortality; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology* / Q000401:mortality; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood / Q000453:epidemiology* / Q000401:mortality / Q000821:virology
chemical_list: D015415:Biomarkers; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies