title: Homocysteine, fibrinogen and lipid profile in children of young adults with coronary artery disease.
abstract: Plasma homocysteine (9.05 ± 4.78 vs 5.93 ± 1.46 umol/L, P<0.01), plasma fibrinogen (313.76 ± 80.02 vs 275.47 ± 53.77 mg/dL, P<0.01), serum total cholesterol (171.64 ± 35.48 vs 152.62 ± 25.40 mg/dL, P<0.01), serum LDL cholesterol (109.51 ± 36.93 vs 87.6 ± 21.6 mg/dL, P<0.01) and fasting blood sugar (99.89 ± 7.46 vs 90.29 ± 9.85 mg/dL, ;were significantly higher in children (n=45) of young adults (<45 y) with coronary artery disease as compared to control group (n=45). No significant correlation was found for plasma homocysteine level of children with that of their parents in either group, whereas significant correlation was found for plasma fibrinogen of children with their parents in both the groups.
authors.affiliation: Department of Pediatrics and Biochemistry, Maulana Azad Medical College and GB Pant Hospital, New Delhi, India. anitakhalil@yahoo.com
authors.forename: Anita
authors.initials: A
authors.lastname: Khalil
authors.forename: Kausik
authors.initials: K
authors.lastname: Mandal
authors.forename: Sumaira
authors.initials: S
authors.lastname: Khalil
authors.forename: V
authors.initials: V
authors.lastname: Mallika
mesh_terms: D000293:Adolescent; D000328:Adult; D001774:Blood Chemical Analysis; D002648:Child; D002675:Child, Preschool; D003324:Coronary Artery Disease / Q000097:blood* / Q000453:epidemiology; D005340:Fibrinogen / Q000378:metabolism*; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D007194:India / Q000453:epidemiology; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D010290:Parents; D012307:Risk Factors
chemical_list: D008055:Lipids; D006710:Homocysteine; D005340:Fibrinogen