title: Myopathy presenting as a sole manifestation of hypothyroidism.
abstract: Myopathy as the sole manifestation of hypothyroidism is rare although muscle weakness, aches and cramps, stiffness and delayed tendon jerk relaxation are the usual features of hypothyroid associated myopathy. We describe a patient with primary hypothyroidism, presenting solely with a clinical picture of myositis with very high levels of creatine phosphokinase (CPK), which normalised after 12 weeks of treatment with levothyroxine.
authors.affiliation: Department of Medicine, Division of Endocrinology, University College of Medical Sciences , Delhi-95.
authors.forename: S V
authors.initials: SV
authors.lastname: Madhu
authors.forename: Rajesh
authors.initials: R
authors.lastname: Jain
authors.forename: Saket
authors.initials: S
authors.lastname: Kant
authors.forename: Ved
authors.initials: V
authors.lastname: Prakash
authors.forename: Vinod
authors.initials: V
authors.lastname: Kumar
mesh_terms: D000328:Adult; D003402:Creatine Kinase / Q000097:blood*; D020249:Hormone Replacement Therapy; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis*; D008297:Male; D018908:Muscle Weakness / Q000188:drug therapy / Q000209:etiology*; D009135:Muscular Diseases / Q000188:drug therapy / Q000209:etiology*; D013974:Thyroxine / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D003402:Creatine Kinase; D013974:Thyroxine