title: Renaissance of brown adipose tissue.
abstract: The recent discovery of functional brown adipose tissue in human adults raised this tissue again into the focus of current investigations concerning human energy homeostasis. Brown fat is a key thermogenic tissue and is essential for non-shivering thermogenesis in the human newborn and hibernating mammals. This review highlights the biological and molecular aspects of brown adipose tissue development and function from the embryonic state to childhood and adolescence.
authors.affiliation: Division of Pediatric Endocrinology and Diabetes, Endocrine Research Laboratory, Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Tews
authors.forename: M
authors.initials: M
authors.lastname: Wabitsch
mesh_terms: D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000196:embryology / Q000254:growth & development / Q000502:physiology*; D000328:Adult; D000818:Animals; D001833:Body Temperature Regulation; D002648:Child; D004734:Energy Metabolism; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D058990:Molecular Targeted Therapy; D009765:Obesity / Q000188:drug therapy / Q000378:metabolism