title: One-pot asymmetric synthesis of γ-nitroaldehydes from aldehydes and nitroalkanes through a catalytic tandem reaction using an amino acid lithium salt.
abstract: One-pot asymmetric synthesis of γ-nitroaldehydes from aldehydes and nitroalkanes was achieved by a catalytic tandem reaction using a primary amino acid lithium salt, O-tert-butyldiphenylsilyl l-tyrosine lithium salt, as a catalyst. Various aryl, alkenyl, and alkyl aldehydes were converted into γ-nitroaldehydes via in situ generation of nitroalkenes.
authors.affiliation: Division of Chemical Process Engineering, Graduate School of Engineering, Hokkaido University, Kita 13-jo Nishi 8, Kita-ku, Sapporo, Hokkaido 060-8628, Japan. myoshida@eng.hokudai.ac.jp
authors.forename: Masanori
authors.initials: M
authors.lastname: Yoshida
authors.forename: Naoki
authors.initials: N
authors.lastname: Kitamikado
authors.forename: Hiroto
authors.initials: H
authors.lastname: Ikehara
authors.forename: Shoji
authors.initials: S
authors.lastname: Hara
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000473:Alkanes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D008094:Lithium / Q000737:chemistry*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000473:Alkanes; D000475:Alkenes; D000596:Amino Acids; D009574:Nitro Compounds; D012492:Salts; D008094:Lithium