title: Characterization of multiblock copolymers by chromatographic techniques.
abstract: Multiblock copolymers (MBC) composed of blocks of poly(1,4-dioxanone) (PPDO) and poly(e-caprolactone) (PCL) were investigated in order to gain information on the extend of chemical heterogeneity of the samples. A gradient chromatographic method was established allowing separation of purely PPDO- from purely PCL-containing chains. Application of the gradient to MBC made of PPDO- and PCL-diols connected by trimethylhexamethylene diisocyanate (TMDI) resulted in two well separated peaks which were analyzed by means of FTIR, 1H-NMR and pyrolysis GC-MS. It was shown that the first peak was composed to a large extent of PPDO and only lower amounts of PCL were incorporated. Conversely, the second peak consisted predominantly of PCL with only a minor fraction of PPDO. Thus, the MBCs having PPDO and PCL segments show an unexpected broad chemical heterogeneity.
authors.affiliation: Deutsches Kunststoff-Institut, Darmstadt, Germany.
authors.forename: Patrick Yoba
authors.initials: PY
authors.lastname: N'Goma
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Radke
authors.forename: Frank
authors.initials: F
authors.lastname: Malz
authors.forename: Hans Jörg
authors.initials: HJ
authors.lastname: Ziegler
authors.forename: Michael
authors.initials: M
authors.lastname: Zierke
authors.forename: Marc
authors.initials: M
authors.lastname: Behl
authors.forename: Andreas
authors.initials: A
authors.lastname: Lendlein
mesh_terms: D000327:Adsorption; D002853:Chromatography, Liquid; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D016687:Polydioxanone / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry*; D011091:Polyesters / Q000138:chemical synthesis / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D011091:Polyesters; C016240:polycaprolactone; D016687:Polydioxanone