title: Total synthesis of (±)-sacidumlignan D.
abstract: The first total synthesis of (±)-sacidumlignan D featuring a Zn-mediated Barbier reaction and reverse Wacker oxidation to form the key γ-lactone, its diastereoselective α-methylation followed by reduction cyclization, was documented.
authors.affiliation: National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India.
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Pandey
authors.forename: C V
authors.initials: CV
authors.lastname: Ramana
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007783:Lactones / Q000737:chemistry*; D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D007783:Lactones; D017705:Lignans; C561165:sacidumlignan D