title: Preparation of "RNase-Free" DNase by Alkylation.
abstract: Characterization of RNA molecules by electrophoresis or hybridization frequently requires nucleic acid concentrations over 1 mg/mL. High molecular weight DNA in a mixture of nucleic acids limits the solubility and interferes with electrophoresis. DNase treatment makes the mixture more soluble, even if DNA degradation is only partial.
authors.affiliation: Department of Biology, University of Utah, Salt Lake City, Utah.
authors.forename: T
authors.initials: T
authors.lastname: Gurney
authors.forename: E G
authors.initials: EG
authors.lastname: Gurney