title: Database resources for proteomics-based analysis of cancer.
abstract: Biological/bioinformatics databases are essential for medical and biological studies. They integrate and organize biologically related information in a structured format and provide researchers with easy access to a variety of relevant data. This review presents an overview of publicly available databases relevant to proteomics studies in cancer research. They include gene/protein expression databases, gene mutation and single nucleotide polymorphisms databases, tumor antigen databases, protein-protein interaction, and biological pathway databases. Automated information retrieval from these databases enables efficient large-scale proteomics data analysis.
authors.affiliation: Cancer Vaccine Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
authors.forename: Guang Lan
authors.initials: GL
authors.lastname: Zhang
authors.forename: David S
authors.initials: DS
authors.lastname: DeLuca
authors.forename: Vladimir
authors.initials: V
authors.lastname: Brusic
mesh_terms: D000951:Antigens, Neoplasm / Q000378:metabolism; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D052138:Genes, Neoplasm / Q000235:genetics; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000276:immunology / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide; D040901:Proteomics / Q000379:methods*; D017422:Sequence Analysis, DNA; D013601:T-Lymphocytes / Q000378:metabolism
chemical_list: D000951:Antigens, Neoplasm