title: Recommendations for assessing patient-reported outcomes and health-related quality of life in patients with urticaria: a GA(2) LEN taskforce position paper.
abstract: The aim of this Global Allergy and Asthma European Network (GA(2)LEN) consensus report is to provide recommendations and suggestions for assessing patient-reported outcomes (PROs) including health-related quality of life in patients with urticaria. We recommend that PROs should be used both in clinical trials and routine practice for the evaluation of urticaria patients. We suggest that PROs should be considered as the primary outcome of future clinical trials. Two validated and disease-specific instruments for assessing PROs are available, the urticaria activity score (for symptoms) and the chronic urticaria questionnaire on quality of life CU-Q(2)oL. This latter tool, CU-Q(2)oL, is available in many languages and should be preferred, where available, over more generic instruments for assessing urticaria-specific effects on quality of life. CU-Q(2)oL is only suited for the investigation of patients with chronic spontaneous urticaria. Similar instruments for other forms of urticaria have yet to be developed and validated. Also, tools for assessing other chronic spontaneous urticaria PROs besides quality of life and symptoms are needed.
authors.affiliation: Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Baiardini
authors.forename: F
authors.initials: F
authors.lastname: Braido
authors.forename: C
authors.initials: C
authors.lastname: Bindslev-Jensen
authors.forename: P J
authors.initials: PJ
authors.lastname: Bousquet
authors.forename: Z
authors.initials: Z
authors.lastname: Brzoza
authors.forename: G W
authors.initials: GW
authors.lastname: Canonica
authors.forename: E
authors.initials: E
authors.lastname: Compalati
authors.forename: A
authors.initials: A
authors.lastname: Fiocchi
authors.forename: W
authors.initials: W
authors.lastname: Fokkens
authors.forename: R
authors.initials: R
authors.lastname: Gerth van Wijk
authors.forename: A
authors.initials: A
authors.lastname: Giménez-Arnau
authors.forename: K
authors.initials: K
authors.lastname: Godse
authors.forename: C
authors.initials: C
authors.lastname: Grattan
authors.forename: J J
authors.initials: JJ
authors.lastname: Grob
authors.forename: S
authors.initials: S
authors.lastname: La Grutta
authors.forename: D
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authors.lastname: Kalogeromitros
authors.forename: E
authors.initials: E
authors.lastname: Kocatürk
authors.forename: C
authors.initials: C
authors.lastname: Lombardi
authors.forename: A
authors.initials: A
authors.lastname: Mota-Pinto
authors.forename: E
authors.initials: E
authors.lastname: Ridolo
authors.forename: S S
authors.initials: SS
authors.lastname: Saini
authors.forename: M
authors.initials: M
authors.lastname: Sanchez-Borges
authors.forename: G E
authors.initials: GE
authors.lastname: Senna
authors.forename: I
authors.initials: I
authors.lastname: Terreehorst
authors.forename: A
authors.initials: A
authors.lastname: Todo Bom
authors.forename: E
authors.initials: E
authors.lastname: Toubi
authors.forename: J
authors.initials: J
authors.lastname: Bousquet
authors.forename: T
authors.initials: T
authors.lastname: Zuberbier
authors.forename: Marcus
authors.initials: M
authors.lastname: Maurer
mesh_terms: D002908:Chronic Disease; D002986:Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014581:Urticaria / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy*