title: Pneumococcal native aortic valve endocarditis with mycotic abdominal aortic aneurysm, paraspinal and iliopsoas abscesses and pneumonia revealing a multiple myeloma.
abstract: We report a rare case of multiple myeloma presenting with native aortic valve endocarditis with secondary embolic mycotic abdominal aortic aneurysm, contiguous paraspinal and iliopsoas abscesses, and pneumonia due to Streptococcus pneumoniae in a Chinese man. He was treated with aortic valve replacement, endovascular stenting of aneurysm, image-guided drainage of abscesses, and a 6-week course of endocarditic antibiotic therapy followed by chronic suppressive antibiotic therapy. Cases of multiple myeloma presenting with invasive pneumococcal infection were reviewed.
authors.affiliation: Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Jasper F W
authors.initials: JFW
authors.lastname: Chan
authors.affiliation: Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Gloria Y Y
authors.initials: GYY
authors.lastname: Hwang
authors.affiliation: Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Sophia
authors.initials: S
authors.lastname: Lamb
authors.affiliation: Department of Pathology and Clinical Biochemistry, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Gavin S W
authors.initials: GSW
authors.lastname: Chan
authors.affiliation: Department of Pathology and Clinical Biochemistry, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Jason C C
authors.initials: JCC
authors.lastname: So
authors.affiliation: Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Sally S M
authors.initials: SSM
authors.lastname: Leung
authors.affiliation: Carol Yu Centre for Infection, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.|Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Kelvin K W
authors.initials: KKW
authors.lastname: To
authors.affiliation: Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Iris W S
authors.initials: IWS
authors.lastname: Li
authors.affiliation: Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Vincent C C
authors.initials: VCC
authors.lastname: Cheng
authors.affiliation: Carol Yu Centre for Infection, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.|Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR.
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D001021:Aortic Valve / Q000473:pathology; D044466:Asian People; D004322:Drainage; D004697:Endocarditis, Bacterial / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011008:Pneumococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D016659:Psoas Abscess / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D015607:Stents; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents