title: Compensation of missed fractions without knowledge of radiobiological parameters.
abstract: The purpose of this work was to develop simple formulas that can be used to estimate the biologic effect of missed radiotherapy fractions independently of radiobiological parameters. This is achieved by expressing the limits in biologically effective dose for very low or very high radiobiological parameter ratios. Worked examples are given.
authors.affiliation: Department of Radiation Physics, Princess Margaret Hospital, Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. marco.carlone@rmp.uhn.on.ca
authors.forename: Marco
authors.initials: M
authors.lastname: Carlone
mesh_terms: D000465:Algorithms; D001071:Appointments and Schedules; D019583:Dose Fractionation, Radiation; D019983:Guideline Adherence; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D010347:Patient Care Planning; D018787:Radiation Oncology / Q000379:methods*; D011853:Radiobiology; D012062:Relative Biological Effectiveness; D013997:Time Factors