title: Possible genetic sign of heat stress adaptation in Hungarian Grey Bos taurus breed.
abstract: The synthesis of Heat Shock Protein 70.2 mRNA is also regulated by the Upper Promoter elements of the gene. This promoter region is polymorphic in cattle. These polymorphisms have a major effect on the activity of the mRNA transcription. In a comparison of quantity of transcribed mRNA from the wild type and AP2 mutant allele the wild type can produce 2-3-fold more transcripts.The Hungarian Grey Cattle (HG) and Norwegian Red (NFR) as control breed were genotyped with PCR-RFLP method. Our results showed that the frequencies of alleles in breeds (p(wt)HG = 0.859419, p(wt)NFR = 0.5) are different. The effective response to heat stress in the Norwegian Red seems to be less important than in the Hungarian Grey breed. The extensive keeping in hot and arid region during centuries could have been proved as selection pressure for the heat tolerance.Our results combined with the global climate forecasts emphasize the role of autochthonous, well adopted, heat tolerant breeds in the near future.
authors.affiliation: Department of Animal Breeding, Nutrition and Laboratory Animal Science, Faculty of Veterinary Science, Szent István University, István u. 2 H-1078, Budapest, Hungary. marotiagots.akos@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Maróti-Agóts
authors.forename: I
authors.initials: I
authors.lastname: Bodó
authors.forename: L
authors.initials: L
authors.lastname: Jávorka
authors.forename: Alice
authors.initials: A
authors.lastname: Gyurmán
authors.forename: N
authors.initials: N
authors.lastname: Solymosi
authors.forename: Petra
authors.initials: P
authors.lastname: Zenke
authors.forename: Marita
authors.initials: M
authors.lastname: Skogseth
authors.forename: L
authors.initials: L
authors.lastname: Zöldág
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics* / Q000502:physiology*; D000818:Animals; D001947:Breeding; D002417:Cattle / Q000235:genetics* / Q000502:physiology*; D005787:Gene Frequency / Q000235:genetics / Q000502:physiology; D005838:Genotype; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics / Q000502:physiology; D018882:Heat Stress Disorders / Q000209:etiology / Q000235:genetics / Q000517:prevention & control*; D006358:Hot Temperature / Q000009:adverse effects; D006814:Hungary; D011110:Polymorphism, Genetic / Q000235:genetics / Q000502:physiology; D011401:Promoter Regions, Genetic / Q000235:genetics / Q000502:physiology
chemical_list: D018840:HSP70 Heat-Shock Proteins