title: [Diagnostics of inflammation activity in infectious endocarditis].
abstract: This work was designed to analyse dynamics of inflammation markers (C-reactive protein, TNF-alpha) and procalcitonin in 66 patients with infectious endocarditis (IE) followed up during 6 months. Comparison of clinical observations and laboratory data revealed specific trends in these parameters in patients with different clinical course of IE and at its different stages. Some of the changes are shown to be responsible for the unfavourable prognosis of IE. TNF-alpha levels are considered to be a sensitive and informative index of the patients" clinical conditions throughout the entire period of IE evolvement.
authors.forename: T A
authors.initials: TA
authors.lastname: Fedorova
authors.forename: V N
authors.initials: VN
authors.lastname: Iakovlev
authors.forename: N A
authors.initials: NA
authors.lastname: Semenenko
authors.forename: S Ia
authors.initials: SIa
authors.lastname: Tazina
authors.forename: A P
authors.initials: AP
authors.lastname: Roĭtman
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Shutov
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism*; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D018450:Disease Progression; D004697:Endocarditis, Bacterial / Q000097:blood / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006023:Glycoproteins; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011498:Protein Precursors / Q000097:blood*; D012189:Retrospective Studies; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*; D055815:Young Adult
chemical_list: C000606589:CALCA protein, human; D006023:Glycoproteins; D011498:Protein Precursors; D014409:Tumor Necrosis Factor-alpha; D002116:Calcitonin; D002097:C-Reactive Protein; D015740:Calcitonin Gene-Related Peptide