title: [Selective hemoperfusion in gram-negative severe sepsis of patients after cardiac surgery: a prospective randomized study].
abstract: Early in the new millennium, sepsis remains one of the most urgent problems of modern reanimatology. Endotoxin, a component of the cell wall of gram-negative bacteria is of paramount importance in the pathogenesis of sepsis. Complex intensive care for severe sepsis involves selective endotoxin hemoperfusion with Polymyxin B and Alteco LPS adsorber, which has been performed in 2 patients. This study will enable specialists to formulate their opinion as to whether it is expedient to incorporate selective endotoxin hemoperfusion into complex intensive care for severe sepsis.
authors.forename: M B
authors.initials: MB
authors.lastname: Iarustovskiĭ
authors.forename: M V
authors.initials: MV
authors.lastname: Abramian
authors.forename: Z V
authors.initials: ZV
authors.lastname: Popok
authors.forename: E I
authors.initials: EI
authors.lastname: Nazarova
authors.forename: O S
authors.initials: OS
authors.lastname: Stupchenko
authors.forename: D A
authors.initials: DA
authors.lastname: Popov
authors.forename: M G
authors.initials: MG
authors.lastname: Pliushch
mesh_terms: D018806:APACHE; D006348:Cardiac Surgical Procedures; D004311:Double-Blind Method; D016905:Gram-Negative Bacterial Infections / Q000097:blood / Q000382:microbiology / Q000628:therapy*; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D008070:Lipopolysaccharides / Q000097:blood; D011112:Polymyxin B / Q000008:administration & dosage / Q000627:therapeutic use; D011183:Postoperative Complications / Q000097:blood / Q000382:microbiology / Q000628:therapy*; D011446:Prospective Studies; D018805:Sepsis / Q000097:blood / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D008070:Lipopolysaccharides; D011112:Polymyxin B