title: Cut-off value of 1-h, 50-g glucose challenge test for screening of gestational diabetes mellitus in an Iranian population.
abstract: OBJECTIVE
  This study aimed to investigate the cut-off value of the glucose challenge test in an Iranian population.
  
  
  METHODS
  A total of 1804 consecutive native Iranian women who underwent a glucose challenge test were prospectively investigated. The test was performed between 24 and 28 weeks of gestation; each subject received a 50-g oral glucose load regardless of her fasting or fed state; the 1-h venous plasma glucose level was then determined. Women exceeding 130 mg/dl received the diagnostic 100-g, 3-h oral glucose tolerance test to determine whether or not they had gestational diabetes mellitus.
  
  
  RESULTS
  The prevalence of the glucose challenge test for the whole cohort was 7.2%. The receiver-operator characteristic curve identified a glucose challenge test finding above 135 mg/dl as the cut-off value for detecting gestational diabetes mellitus, which showed a sensitivity and specificity of 95% and 80%, respectively.
  
  
  CONCLUSIONS
  Our results suggest that the cut-off value of a 50-g glucose challenge test is 135 mg/dl to identify pregnancies with gestational diabetes mellitus in an Iranian population.
authors.affiliation: Department of Reproductive Health, Tarbiat Modares University, Tehran, Islamic Republic of Iran. s.behboudi@modares.ac.ir
authors.forename: Samira Behboudi
authors.initials: SB
authors.lastname: Gandevani
authors.forename: Ahia
authors.initials: A
authors.lastname: Garshasbi
authors.forename: Shiva
authors.initials: S
authors.lastname: Dibaj
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008403:Mass Screening / Q000379:methods*; D011247:Pregnancy; D015995:Prevalence; D011446:Prospective Studies; D012016:Reference Values; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose; D005947:Glucose