title: Neurological soft signs in obsessive compulsive disorder with good and poor insight.
abstract: OBJECTIVE
  Obsessive compulsive disorder (OCD) is a clinically heterogeneous disorder; OCD with poor insight has been suggested to be a specific clinical subtype. Neurological soft signs (NSSs) may be helpful to identify the specific subtypes of OCD patients.
  
  
  METHODS
  In the present study, we aimed to compare OCD patients with poor insight with OCD patients having good insight, and healthy individuals. Sixty-four OCD patients (38 with good insight and 26 with poor insight), and 32 healthy subjects were enrolled in the present study. The Overvalued Ideas Scale (OVIS) was used to determine OCD patients with poor insight. NSSs were assessed by using the Neurological Evaluation Scale (NES).
  
  
  RESULTS
  Two OCD groups had significantly higher total NES scores compared to controls (p=.000). Compared to healthy controls, OCD patients with poor insight performed significantly worse on all NES subscales, and they had significantly more NSSs on motor coordination, and sensory integration subscales compared to the OCD with good insight group.
  
  
  CONCLUSIONS
  Our results suggested that OCD patients with poor insight exhibit more extensive neurodevelopmental impairments compared to OCD patients with good insight.
authors.affiliation: Pamukkale University, Medicine Faculty, Psychiatry Department, Doktorlar Cd. 20100 Denizli, Turkey. filizlal@yahoo.com
authors.forename: Filiz
authors.initials: F
authors.lastname: Karadag
authors.forename: Selim
authors.initials: S
authors.lastname: Tumkaya
authors.forename: Duygu
authors.initials: D
authors.lastname: Kırtaş
authors.forename: Muharrem
authors.initials: M
authors.lastname: Efe
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Alacam
authors.forename: Nalan K
authors.initials: NK
authors.lastname: Oguzhanoglu
mesh_terms: D000328:Adult; D003627:Data Interpretation, Statistical; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology* / Q000523:psychology; D009483:Neuropsychological Tests; D009771:Obsessive-Compulsive Disorder / Q000145:classification / Q000188:drug therapy / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology; D012649:Self Concept; D012677:Sensation / Q000502:physiology; D012959:Socioeconomic Factors