title: Persistent orofacial muscle pain.
abstract: The pathophysiology of persistent orofacial myalgia has been the centre of much controversy. In this article we suggest a novel descriptive term; 'persistent orofacial muscle pain' (POMP) and review current evidence that supports the hypothesis that the induction of POMP involves the interplay between a peripheral nociceptive source in muscle, a faulty central nervous system component and decreased coping ability. In this context it is widely accepted that a complex interaction of variable intrinsic and extrinsic factors act to induce POMP and dysfunction.
authors.affiliation: Department of Oral Medicine, The Faculty of Dentistry, Hebrew University-Hadassah, Jerusalem, Israel. benoliel@cc.huji.ac.il
authors.forename: R
authors.initials: R
authors.lastname: Benoliel
authors.forename: P
authors.initials: P
authors.lastname: Svensson
authors.forename: G M
authors.initials: GM
authors.lastname: Heir
authors.forename: D
authors.initials: D
authors.lastname: Sirois
authors.forename: J
authors.initials: J
authors.lastname: Zakrzewska
authors.forename: J
authors.initials: J
authors.lastname: Oke-Nwosu
authors.forename: S R
authors.initials: SR
authors.lastname: Torres
authors.forename: M S
authors.initials: MS
authors.lastname: Greenberg
authors.forename: G D
authors.initials: GD
authors.lastname: Klasser
authors.forename: J
authors.initials: J
authors.lastname: Katz
authors.forename: E
authors.initials: E
authors.lastname: Eliav
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000223:Adaptation, Psychological / Q000502:physiology; D002490:Central Nervous System / Q000503:physiopathology; D017271:Craniomandibular Disorders / Q000209:etiology / Q000503:physiopathology; D003766:Dental Occlusion; D005157:Facial Pain / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008410:Masticatory Muscles / Q000294:innervation / Q000503:physiopathology*; D009479:Neuropeptides / Q000502:physiology; D009619:Nociceptors / Q000502:physiology; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000209:etiology / Q000503:physiopathology
chemical_list: D009479:Neuropeptides