title: Size dependent macrophage responses and toxicological effects of Ag nanoparticles.
abstract: The immune-response of macrophages is an important area of investigation since it represents the major pathway by which early-stage defense barriers are established in skin, lungs, and mucosal systems to counteract foreign objects. In this study, we have examined the size-dependent inflammatory and toxicological effects of nanostructured silver particles (nano-Ag) on macrophage immune cells.
authors.affiliation: Department of Microbiology, College of Medicine, Yonsei University, Seongsanno 250, Seodaemun-gu, Seoul, 120-752, Korea.
authors.forename: Jeongsin
authors.initials: J
authors.lastname: Park
authors.forename: Dae-Hyoun
authors.initials: DH
authors.lastname: Lim
authors.forename: Hyun-Jeong
authors.initials: HJ
authors.lastname: Lim
authors.forename: Taejung
authors.initials: T
authors.lastname: Kwon
authors.forename: Jin-sil
authors.initials: JS
authors.lastname: Choi
authors.forename: Sohee
authors.initials: S
authors.lastname: Jeong
authors.forename: In-Hong
authors.initials: IH
authors.lastname: Choi
authors.forename: Jinwoo
authors.initials: J
authors.lastname: Cheon
mesh_terms: D002460:Cell Line; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism; D016209:Interleukin-8 / Q000096:biosynthesis; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity*; D010316:Particle Size; D010587:Phagocytosis / Q000187:drug effects / Q000276:immunology; D017382:Reactive Oxygen Species / Q000378:metabolism; D012834:Silver / Q000737:chemistry* / Q000633:toxicity*
chemical_list: D016209:Interleukin-8; D017382:Reactive Oxygen Species; D012834:Silver