title: Residential proximity to heavy traffic and birth weight in Shizuoka, Japan.
abstract: An association between exposure to traffic-related air pollution and reduced birth weight has been suggested. However, previous studies have failed to adjust for maternal size, which is an indicator of individual genetic growth potential. Therefore, we evaluated the association of air pollution with birth weight, term low birth weight (term-LBW), and small for gestational age (SGA), with adjustment for maternal size. Individual data were extracted from a database that is maintained by a maternal and perinatal care center in Shizuoka, Japan. We identified liveborn singleton births (n=14,204). Using geocoded residential information, each birth was assigned a number of traffic-based exposure indicators: distance to a major road; distance-weighted traffic density; and estimated concentration of nitrogen dioxide by land use regression. The multivariate adjusted odds ratios and their 95% confidence intervals (CIs) for the associations between exposure indicators and outcomes were then estimated using logistic regression models. Overall, exposure indicators of air pollution showed no clear pattern of association. Although there are many limitations, we did not find clear associations between birth-weight-related outcomes and the three markers of traffic-related air pollution.
authors.affiliation: Department of Public Health and Health Policy, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. saori_ksm@ybb.ne.jp
authors.forename: Saori
authors.initials: S
authors.lastname: Kashima
authors.forename: Hiroo
authors.initials: H
authors.lastname: Naruse
authors.forename: Takashi
authors.initials: T
authors.lastname: Yorifuji
authors.forename: Shigeru
authors.initials: S
authors.lastname: Ohki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Murakoshi
authors.forename: Soshi
authors.initials: S
authors.lastname: Takao
authors.forename: Toshihide
authors.initials: T
authors.lastname: Tsuda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Doi
mesh_terms: D000393:Air Pollutants / Q000378:metabolism / Q000506:poisoning*; D001724:Birth Weight / Q000187:drug effects* / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D004781:Environmental Exposure / Q000032:analysis*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D009585:Nitrogen Dioxide / Q000378:metabolism / Q000506:poisoning*; D011247:Pregnancy; D012189:Retrospective Studies; D012621:Seasons; D012959:Socioeconomic Factors; D001335:Vehicle Emissions / Q000506:poisoning*
chemical_list: D000393:Air Pollutants; D001335:Vehicle Emissions; D009585:Nitrogen Dioxide