title: Effect of preparative conditions on crystallinity of apatite particles obtained from simulated body fluids.
abstract: Preparation of colloidal hydroxyapatite (HAp) particles under body fluid conditions was investigated with focusing on the effect of preparative conditions on crystallinity of the resulting particles. Tris(hydroxymethyl)aminomethane was added to 1.5SBF (a solution having 1.5 times higher ion concentrations than those of a simulated body fluid, SBF) to increase the solution pH, which resulted in induction of homogeneous nucleation of HAp in the solution. Colloidal HAp particles having diameters about 300 nm were obtained. When the reaction was proceeded at 70°C and the sample was dried by heating, it was effective to obtain HAp particles having high crystallinity. Experimental results support that remaining water in the sample contributed to increase HAp crystallinity.
authors.affiliation: Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, 12-1 Ichigayafunagawara-machi, Shinjuku-ku, Tokyo 162-0826, Japan. mhashizu@ci.kagu.tus.ac.jp
authors.forename: Mineo
authors.initials: M
authors.lastname: Hashizume
authors.forename: Yuka
authors.initials: Y
authors.lastname: Nagasawa
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Suzuki
authors.forename: Shin
authors.initials: S
authors.lastname: Kawashima
authors.forename: Masanobu
authors.initials: M
authors.lastname: Kamitakahara
mesh_terms: D001826:Body Fluids / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000379:methods; D003102:Colloids / Q000737:chemistry*; D003460:Crystallization; D006882:Hydroxyapatites / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties
chemical_list: D003102:Colloids; D006882:Hydroxyapatites