title: Selective solid-phase extraction using molecularly imprinted polymer for analysis of methamidophos in water and soil samples.
abstract: An analytical methodology for the analysis of methamidophos in water and soil samples incorporating a molecularly imprinted solid-phase extraction process using methamidophos-imprinted polymer was developed. Binding study demonstrated that the polymer exhibited excellent affinity and high selectivity to the methamidophos. Evidence was also found by FT-IR analysis that hydrogen bonding between the CO(2)H in the polymer cavities and the NH(2) and P=O of the template was the origin of methamidophos recognition. The use of molecularly imprinted solid-phase extraction improved the accuracy and precision of the GC method and lowered the limit of detection. The recovery of methamidophos extracted from a 10.0 g soil sample at the 100 ng/g spike level was 95.4%. The limit of detection was 3.8 ng/g. The recovery of methamidophos extracted from 100 mL tap and river water at 1 ng/mL spike level was 96.1% and 95.8%, and the limits of detection were 10 and 13 ng/L respectively. These molecularly imprinted solid-phase extraction procedures enabled selective extraction of polar methamidophos successfully from water and soil samples, demonstrating the potential of molecularly imprinted solid-phase extraction for rapid, selective, and cost-effective sample pretreatment.
authors.affiliation: Shandong Supervision and Inspection Institute for Product Quality, Jinan, China. zlshen88@mail.ustc.edu.cn
authors.forename: Zhong-Lan
authors.initials: ZL
authors.lastname: Shen
authors.forename: Dong
authors.initials: D
authors.lastname: Yuan
authors.forename: Qing-De
authors.initials: QD
authors.lastname: Su
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhu
authors.forename: Yan-Ming
authors.initials: YM
authors.lastname: Liu
mesh_terms: D001665:Binding Sites; D002849:Chromatography, Gas; D005583:Fourier Analysis; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D057230:Limit of Detection; D054802:Molecular Imprinting / Q000379:methods*; D009946:Organothiophosphorus Compounds / Q000032:analysis / Q000302:isolation & purification*; D011108:Polymers / Q000138:chemical synthesis; D012680:Sensitivity and Specificity; D012987:Soil / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis; D018508:Water Purification / Q000379:methods*
chemical_list: D009946:Organothiophosphorus Compounds; D011108:Polymers; D012987:Soil; D014874:Water Pollutants, Chemical; D014867:Water; C014655:methamidophos