title: Prospective randomized controlled trial of traditional laparoscopic cholecystectomy versus single-incision laparoscopic cholecystectomy: report of preliminary data.
abstract: BACKGROUND
  This study presents preliminary data from a prospective randomized multicenter, single-blinded trial of single-incision laparoscopic cholecystectomy (SILC) versus standard laparoscopic cholecystectomy (4PLC).
  
  
  METHODS
  Patients with symptomatic gallstones, polyps, or biliary dyskinesia (ejection fraction <30%) were randomized to SILC or 4PLC. Data included operative time, estimated blood loss, length of skin and fascial incisions, complications, pain, satisfaction and cosmetic scoring, and conversion.
  
  
  RESULTS
  Operating room time was longer with SILC (n = 50) versus 4PLC (n = 33). No differences were seen in blood loss, complications, or pain scores. Body image scores and cosmetic scores at 1, 2, 4, and 12 weeks were significantly higher for SILC. Satisfaction scores, however, were similar.
  
  
  CONCLUSIONS
  Preliminary results from this prospective trial showed SILC to be safe compared with 4PLC although operative times were longer. Cosmetic scores were higher for SILS compared with 4PLC. Satisfaction scores were similar although both groups reported a significantly higher preference towards SILC.
authors.affiliation: University Hospitals of Cleveland, Case Medical Center, Cleveland, OH 44106, USA. Jeffrey.marks@uhhospitals.org
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Marks
authors.forename: Roberto
authors.initials: R
authors.lastname: Tacchino
authors.forename: Kurt
authors.initials: K
authors.lastname: Roberts
authors.forename: Raymond
authors.initials: R
authors.lastname: Onders
authors.forename: George
authors.initials: G
authors.lastname: Denoto
authors.forename: Paraskevas
authors.initials: P
authors.lastname: Paraskeva
authors.forename: Homero
authors.initials: H
authors.lastname: Rivas
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Soper
authors.forename: Alexander
authors.initials: A
authors.lastname: Rosemurgy
authors.forename: Sajani
authors.initials: S
authors.lastname: Shah
mesh_terms: D000328:Adult; D000368:Aged; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects* / Q000379:methods*; D002769:Cholelithiasis / Q000601:surgery; D004954:Esthetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016037:Single-Blind Method; D016896:Treatment Outcome