title: Clinical presentation of adult coeliac disease.
abstract: The mode of presentation of coeliac disease has been changing to more atypical or silent disease. Few studies described the clinical presentation of adult coeliac disease in Ireland in recent years. We retrospectively collected the clinical data for all patients who had a diagnosis of coeliac disease made in our centre between January 07 and December 08. Forty seven adults, predominantly females (n = 30), had a confirmed diagnosis of coeliac disease made during the study period. In our patient cohort, the presenting symptom was diarrhoea in 19 (40%) patients, while 16 patients (34%) did not have any G.I. symptoms, 10 (21%) presented with anaemia. Females presented at a significantly younger age compared to males, with median ages at diagnosis of 44.5 and 57 years, respectively (p = 0.04). Females also presented more commonly with non G.I. symptoms (p = 0.07). The reasons behind this gender difference need further study.
authors.affiliation: Department of Gastroenterology, Beaumont Hospital, Beaumont, Dublin 9.
authors.forename: T
authors.initials: T
authors.lastname: Tajuddin
authors.forename: S
authors.initials: S
authors.lastname: Razif
authors.forename: R
authors.initials: R
authors.lastname: Dhar
authors.forename: J
authors.initials: J
authors.lastname: Thorne
authors.forename: F E
authors.initials: FE
authors.lastname: Murray
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002446:Celiac Disease / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D011503:Transglutaminases / Q000032:analysis; D015431:Weight Loss
chemical_list: D011503:Transglutaminases