title: Protein tyrosine phosphatase interacting protein 51--a jack-of-all-trades protein.
abstract: Protein tyrosine phosphatase interacting protein 51 (PTPIP51) interacts both in vitro and in vivo with PTP1B, a protein tyrosine phosphatase involved in cellular regulation. PTPIP51 is known to be expressed in many different types of tissues. It is involved in cellular processes such as proliferation, differentiation and apoptosis. Nevertheless, the exact cellular function of PTPIP51 is still unknown. The present review summarizes our current knowledge of the PTPIP51 gene and its mRNA and protein structure.
authors.affiliation: Institute of Anatomy and Cell Biology, Justus-Liebig-University, Giessen, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Brobeil
authors.forename: Manuel
authors.initials: M
authors.lastname: Bobrich
authors.forename: Monika
authors.initials: M
authors.lastname: Wimmer
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D015151:Immunoblotting; D051379:Mice; D024101:Mitochondrial Proteins / Q000096:biosynthesis* / Q000235:genetics* / Q000378:metabolism; D017027:Protein Tyrosine Phosphatases / Q000096:biosynthesis* / Q000235:genetics* / Q000378:metabolism; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D051381:Rats
chemical_list: D024101:Mitochondrial Proteins; D012333:RNA, Messenger; C534801:PTPIP51 protein, mouse; D017027:Protein Tyrosine Phosphatases; C515449:RMDN3 protein, human; C524645:Rmdn3 protein, rat