title: Veterinary DNA vaccines.
abstract: Vaccination has relied, in general, on two technologies for the production of antigenic material suitable for the generation of a protective immune response; live infectious agents and inactivated or subunit vaccine preparations. Live infectious agents generally are most efficacious, but there is always a risk factor when using this type of vaccine. The major advantage of inactivated and subunit preparations is their safety; however, limited efficacy and duration of immunity and/or high cost may limit the usefulness of these types of vaccines. DNA vaccines represent a new and potentially powerful approach to the development of subunit vaccines.
authors.affiliation: Veterinary Infectious Disease Organization, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
authors.forename: S
authors.initials: S
authors.lastname: van Drunen Littel-van den Hurk
authors.forename: R P
authors.initials: RP
authors.lastname: Braun
authors.forename: L A
authors.initials: LA
authors.lastname: Babiuk