title: [The new biomarkers of prostate cancer].
abstract: Biomarkers of prostate cancer can assess a presence risk or an evolution risk of the disease. The integration of temporal and clinical data during the interpretation of a PSA dosage improves its performance. Trough a performing algorithm, the Phi index (Prostate Health Index) combines the results of total PSA, free PSA, and pro-PSA. The ration of urinary PCA3 and urinary PSA determines a powerful marker to be used in difficult diagnostic situations. Gene fusions in prostate cancer are promising biomarkers and eventual therapeutic targets. The cost of these new biomarkers is limiting their current use to individual situations.
authors.affiliation: Service d'Urologie, Hôpital Bicêtre, 78, rue du Général Leclerc, 94275 Le Kremlin-Bicêtre Cedex, France. thomas.bessede@gmail.com
authors.forename: T
authors.initials: T
authors.lastname: Bessede
authors.forename: B
authors.initials: B
authors.lastname: Malavaud
mesh_terms: D000951:Antigens, Neoplasm / Q000652:urine; D015415:Biomarkers / Q000097:blood / Q000652:urine; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood* / Q000652:urine*
chemical_list: D000951:Antigens, Neoplasm; D015415:Biomarkers; C479341:prostate cancer antigen 3, human; D017430:Prostate-Specific Antigen