title: Development of a real-time clinical decision support system upon the Web MVC-based architecture for prostate cancer treatment.
abstract: BACKGROUND
  A real-time clinical decision support system (RTCDSS) with interactive diagrams enables clinicians to instantly and efficiently track patients' clinical records (PCRs) and improve their quality of clinical care. We propose a RTCDSS to process online clinical informatics from multiple databases for clinical decision making in the treatment of prostate cancer based on Web Model-View-Controller (MVC) architecture, by which the system can easily be adapted to different diseases and applications.
  
  
  METHODS
  We designed a framework upon the Web MVC-based architecture in which the reusable and extractable models can be conveniently adapted to other hospital information systems and which allows for efficient database integration. Then, we determined the clinical variables of the prostate cancer treatment based on participating clinicians' opinions and developed a computational model to determine the pretreatment parameters. Furthermore, the components of the RTCDSS integrated PCRs and decision factors for real-time analysis to provide evidence-based diagrams upon the clinician-oriented interface for visualization of treatment guidance and health risk assessment.
  
  
  RESULTS
  The resulting system can improve quality of clinical treatment by allowing clinicians to concurrently analyze and evaluate the clinical markers of prostate cancer patients with instantaneous clinical data and evidence-based diagrams which can automatically identify pretreatment parameters. Moreover, the proposed RTCDSS can aid interactions between patients and clinicians.
  
  
  CONCLUSIONS
  Our proposed framework supports online clinical informatics, evaluates treatment risks, offers interactive guidance, and provides real-time reference for decision making in the treatment of prostate cancer. The developed clinician-oriented interface can assist clinicians in conveniently presenting evidence-based information to patients and can be readily adapted to an existing hospital information system and be easily applied in other chronic diseases.
authors.affiliation: Department of Health Risk Management, School of Public Health, China Medical University, 91 Hsueh-Shi Road, Taichung 40402, Taiwan. snowlin@mail.cmu.edu.tw
authors.forename: Hsueh-Chun
authors.initials: HC
authors.lastname: Lin
authors.forename: Hsi-Chin
authors.initials: HC
authors.lastname: Wu
authors.forename: Chih-Hung
authors.initials: CH
authors.lastname: Chang
authors.forename: Tsai-Chung
authors.initials: TC
authors.lastname: Li
authors.forename: Wen-Miin
authors.initials: WM
authors.lastname: Liang
authors.forename: Jong-Yi Wang
authors.initials: JY
authors.lastname: Wang
mesh_terms: D003199:Computer Systems; D020000:Decision Support Systems, Clinical; D006801:Humans; D020407:Internet; D008297:Male; D010353:Patient Education as Topic; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000628:therapy*; D012984:Software