title: [The basis of rehabilitation and treatment in acute period of perinatal cerebral pathology].
abstract: We have examined 89 newborns with perinatal CNS lesions due to critical states at birth. Disturbances of vital functions of the organism developed as a result of severe posthypoxia states at birth that exert a significant effect on patient's quality of life in the following age periods, including the formation of "rough" polyorganic injuries, have been studied. Therefore, the adequate treatment of post-critical states in the neonatal period demands understanding of pathogenetic mechanisms of their development that has formed the basis for using peptide drugs with neuroprotective effect, in particular, cortexin.
authors.forename: T V
authors.initials: TV
authors.lastname: Belousova
authors.forename: L A
authors.initials: LA
authors.lastname: Riazhina
mesh_terms: D001930:Brain Injuries / Q000188:drug therapy* / Q000503:physiopathology* / Q000534:rehabilitation; D002545:Brain Ischemia / Q000188:drug therapy* / Q000503:physiopathology* / Q000534:rehabilitation; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000188:drug therapy* / Q000503:physiopathology* / Q000534:rehabilitation; D007231:Infant, Newborn; D036341:Intercellular Signaling Peptides and Proteins; D008297:Male; D007744:Obstetric Labor Complications / Q000188:drug therapy* / Q000503:physiopathology* / Q000534:rehabilitation; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; C056590:cortexin