title: [Endothelial dysfunction in patients with lower-limb varicose disease and possibilities of correction thereof].
abstract: Endothelium as the main structural unit of the vessel appears to exert a considerable influence on the processes of regulation of the cardiovascular system. The authors generalize herein and present the findings of the studies aimed at investigating endothelial dysfunction in varicose disease. Based on analysing the results of various methods of study they show importance of endothelial dysfunction, followed by discussing possibilities of medicamentous correction thereof, proceeding from pathogenetic mechanisms of its development.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Shevchenko
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Stoĭko
authors.forename: V G
authors.initials: VG
authors.lastname: Gudymovich
authors.forename: A M
authors.initials: AM
authors.lastname: Nikitina
authors.forename: S I
authors.initials: SI
authors.lastname: Trifonov
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D014648:Varicose Veins / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery; D014656:Vascular Surgical Procedures / Q000379:methods; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D014665:Vasodilator Agents