title: Clinical efficacy of a new variant of a foam-based NWPT system.
abstract: OBJECTIVE
  To evaluate the clinical efficacy of a new variant of a foam-based negative wound pressure wound therapy (NPWT) system.
  
  
  METHODS
  A newly available polyurethane foam-based NPWT system (RENASYS-F, Smith & Nephew) was used to treat 18 patients in a prospective, multi-centre study. The patients had a variety of wound types including pressure ulcers, diabetic foot ulcers, traumatic and surgical wounds.
  
  
  RESULTS
  The mean patient age was 48.3 years (range 25-72). Mean treatment duration was 14.6 days (range 5-29). At the end of therapy, 83% (15) wounds had progressed sufficiently, leading to a change in treatment from NPWT. Median reductions in wound area, depth and volume of 31.3%, 45.5% and 74.2% respectively were observed over the course of therapy. This equated to a weekly reduction in area, depth and volume of 12.9%, 20.0% and 32.1% respectively. Exudate level (p = 0.013) and wound malodour (p = 0.03) were significantly reduced between the onset and the end of NPWT. The percentage cover of 'beefy' red granulation tissue in the wound bed was significantly increased (p < 0.001) and non-viable tissue significantly reduced (p = 0.008) between the onset and the end of NPWT.
  
  
  CONCLUSIONS
  These data demonstrate that an alternative foam-based NPWT system (RENASYS-F) is able to address the common treatment goals associated with application of NPWT including reduction in wound dimensions, reduction in exudate levels and an improvement in wound bed quality.
authors.affiliation: Internation Medical Centre, Jeddah, Saudi Arabia.
authors.forename: S
authors.initials: S
authors.lastname: Bondokji
authors.forename: M
authors.initials: M
authors.lastname: Rangaswamy
authors.forename: C
authors.initials: C
authors.lastname: Reuter
authors.forename: Y
authors.initials: Y
authors.lastname: Farajalla
authors.forename: T
authors.initials: T
authors.lastname: Mole
authors.forename: J
authors.initials: J
authors.lastname: Cockwill
authors.forename: J
authors.initials: J
authors.lastname: Smith
mesh_terms: D006097:Granulation Tissue; D006801:Humans; D054843:Negative-Pressure Wound Therapy; D011446:Prospective Studies; D016896:Treatment Outcome; D014945:Wound Healing; D014947:Wounds and Injuries