title: Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations.
abstract: OBJECTIVE
  The aim of the present study is to assess the implant osteointegration, as well as the course of bone regeneration and healing processes, thanks to the sinus lift procedure and by using PRF as a filling material, in association with the Bio-Oss.
  
  
  METHODS
  23 patients, requiring maxillary sinus lift in order to place implants into posterior maxillary region, were involved in this study. Selected cases, in which the height of the residual bone was superior to 5 mm, were adopted for surgical procedure of "one-stage sinus lift" (implant insertion concurrently occured with sinus lift resulting 6-9 months the healing and integration time). Before inserting the implant, a small quantity of filling material was placed in the cavity. For this purpose the bone fragment, stored in saline solution, was employed mixed with Bio-Oss and PRF, after being ground.
  
  
  RESULTS
  All patients reported no pain to percussion, no sign of tissue suffering in the soft peri-implant tissues, the presence of an optimal primary stability of the inserted implants and a significant increase in the peri-implant bone density.
  
  
  CONCLUSIONS
  In all cases included in this protocol, the Authors observed a successful implant-prosthetic rehabilitation, according with Albrektsson criteria.
authors.affiliation: School in "Dental Hygiene", Faculty of Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Inchingolo
authors.forename: M
authors.initials: M
authors.lastname: Tatullo
authors.forename: M
authors.initials: M
authors.lastname: Marrelli
authors.forename: A M
authors.initials: AM
authors.lastname: Inchingolo
authors.forename: S
authors.initials: S
authors.lastname: Scacco
authors.forename: A D
authors.initials: AD
authors.lastname: Inchingolo
authors.forename: G
authors.initials: G
authors.lastname: Dipalma
authors.forename: D
authors.initials: D
authors.lastname: Vermesan
authors.forename: A
authors.initials: A
authors.lastname: Abbinante
authors.forename: R
authors.initials: R
authors.lastname: Cagiano
mesh_terms: D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000601:surgery*; D001804:Blood Transfusion, Autologous; D001861:Bone Regeneration; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation; D003757:Dental Implantation; D005337:Fibrin / Q000627:therapeutic use*; D006801:Humans; D007558:Italy; D008437:Maxilla / Q000000981:diagnostic imaging / Q000601:surgery*; D008439:Maxillary Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D008903:Minerals / Q000627:therapeutic use*; D016348:Osseointegration; D017713:Platelet Transfusion; D012720:Severity of Illness Index; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D008903:Minerals; D005337:Fibrin