title: Antiinflammatory activity of a polyherbal formulation.
abstract: The antiinflammatory activity of the polyherbal formulation Entox(®) was investigated in rats for acute and sub acute models of inflammation using carrageenan-induced rat paw edema and cotton pellet granuloma methods respectively at a dose of 300 mg/kg and 600 mg/kg administered orally. The formulation in doses of 300 mg/kg and 600 mg/kg showed 51.61% and 54.84% inhibition of paw edema, respectively at the end of 3 h. The percent inhibition of granuloma by cotton pellet method was 27.92% and 53.17%, respectively. The formulation showed a significant antiinflammatory activity in both the experimental models and the activity was comparable to that of the standard drug, indomethacin.
authors.affiliation: Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai-400 614, India.
authors.forename: S R
authors.initials: SR
authors.lastname: Deorukhakar
authors.forename: A
authors.initials: A
authors.lastname: Dethe
authors.forename: R R
authors.initials: RR
authors.lastname: Vohra
authors.forename: R
authors.initials: R
authors.lastname: Ghosh
authors.forename: J
authors.initials: J
authors.lastname: Chaudhary
authors.forename: V
authors.initials: V
authors.lastname: Kadam