title: Uncovering a tumor suppressor for triple-negative breast cancers.
abstract: "Triple-negative" breast cancers are aggressive malignancies that respond poorly to treatments. Now Sun et al. (2011) find that the activity of the protein tyrosine phosphatase PTPN12 is lost in a large percentage of this breast cancer subtype, offering molecular drivers and possible therapeutic targets for this heterogeneous and intractable cancer.
authors.affiliation: Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: John G
authors.initials: JG
authors.lastname: Albeck
authors.forename: Joan S
authors.initials: JS
authors.lastname: Brugge