title: [Pluripotency candidate signaling network and transcription factors in domesticated ungulates: a review].
abstract: Domesticated ungulates embryonic stem (ES) cells have great significances in biology and wide application prospects. This review compared the key signaling pathways related with pluripotency between mouse and human ES cells, and the difference of transcription factors in mouse, human and domesticated ungulates ES cells were elaborated. Finally the pluripotency candidate signaling network and transcription factors related in the derivation of domesticated ungulates ES cell were discussed combined with practical experience of ovine embryonic stem cell derivation in our laboratory.
authors.affiliation: Key Laboratory of Animal Biotechnology of Xinjiang, Urumqi 830000, China.
authors.forename: Yuncheng
authors.initials: Y
authors.lastname: Zhao
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhou
authors.forename: Xiuhua
authors.initials: X
authors.lastname: Zhang
authors.forename: Juncheng
authors.initials: J
authors.lastname: Huang
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D002454:Cell Differentiation / Q000502:physiology; D002478:Cells, Cultured; D053595:Embryonic Stem Cells / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D053605:Leukemia Inhibitory Factor / Q000378:metabolism*; D051379:Mice; D020929:Mitogen-Activated Protein Kinase Kinases / Q000378:metabolism*; D039904:Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism*; D012756:Sheep; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism; D051153:Wnt Proteins / Q000378:metabolism
chemical_list: D053605:Leukemia Inhibitory Factor; D014157:Transcription Factors; D051153:Wnt Proteins; D020929:Mitogen-Activated Protein Kinase Kinases