title: Multidisciplinary treatment with chemotherapy, targeted drug, and high-intensity focused ultrasound in advanced pancreatic carcinoma.
abstract: This study reports a case of an advanced pancreatic cancer patient with liver metastasis who was treated with a combination of chemotherapy, targeted drugs, and high-intensity focused ultrasound (HIFU). The abdominal pain was successfully relieved after the HIFU therapy. The patient had an 18-month survival with satisfactory quality of life. Large-scale randomized clinical trials are necessary to evaluate the long-term efficacy of HIFU treatment with or without chemotherapy and/or targeted drug therapy for pancreatic carcinoma.
authors.affiliation: Department of Medical Oncology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, 2nd Hospital of Zhejiang University College of Medicine, Hangzhou, Zhejiang 310009, People's Republic of China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Yuan
authors.forename: Hong
authors.initials: H
authors.lastname: Shen
authors.forename: Xiao-Ye
authors.initials: XY
authors.lastname: Hu
authors.forename: Fei-Ying
authors.initials: FY
authors.lastname: Gu
authors.forename: Mo-Dan
authors.initials: MD
authors.lastname: Li
authors.forename: Xian
authors.initials: X
authors.lastname: Zhong
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D000069347:Erlotinib Hydrochloride; D005260:Female; D057086:High-Intensity Focused Ultrasound Ablation; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy*; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*; D011799:Quinazolines / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D011799:Quinazolines; D003841:Deoxycytidine; D000069347:Erlotinib Hydrochloride; D000093542:Gemcitabine