title: [Preterm labour after adenosine treatment for paroxysmal supraventricular tachycardia during pregnancy, a case report].
abstract: Paroxysmal supraventricular tachycardia is the most frequent arrhythmia among young pregnant women. In case of failure of vagal manoeuvres, their management is preferentially intravenous infusion of adenosine. The in vitro contracturant effect of adenosine on myometrial fibres is known, but very few data are available about the in vivo effect during pregnancy. We report here the case of a 30-week gestational age pregnant woman treated successfully by adenosine for a junctional tachycardia. Adenosine administration was immediately followed by a preterm labour managed by calcium channels blockers tocolysis. Even if causal relationship remains uncertain, this observation is consistent with physiopathological data and should catch physician's attention when initiating this treatment.
authors.affiliation: Service de gynécologie obstétrique, hôpital Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75877 Paris cedex 18, France.
authors.forename: G
authors.initials: G
authors.lastname: Canlorbe
authors.forename: E
authors.initials: E
authors.lastname: Azria
authors.forename: D
authors.initials: D
authors.lastname: Michel
authors.forename: B
authors.initials: B
authors.lastname: Iung
authors.forename: D
authors.initials: D
authors.lastname: Mahieu-Caputo
mesh_terms: D000241:Adenosine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D001034:Apgar Score; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D007752:Obstetric Labor, Premature / Q000139:chemically induced*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000503:physiopathology; D011256:Pregnancy Outcome; D013614:Tachycardia, Paroxysmal / Q000150:complications* / Q000188:drug therapy*; D013617:Tachycardia, Supraventricular / Q000150:complications* / Q000188:drug therapy*; D015149:Tocolytic Agents / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D002121:Calcium Channel Blockers; D015149:Tocolytic Agents; D000241:Adenosine