title: Nucleus lentiformis--a new model for psychiatry?
abstract: In a regions of interest analysis (ROI) of the most frequent psychiatric disorders (schizophrenia, depression, anxiety, addiction), we found the nucleus lentiformis to be the topographical brain region most frequently cited in connection with these disorders in a regions of interest survey of publications between 1990-2010. This structure, which controls particularly motorics, appears to have a much greater importance than has thus far been assumed in the control and modulation of psychiatric disorders. The question of the extent to which this region has its own control function with respect to the disorders should be addressed in further studies along with clarification of possible influence factors on the activity.
authors.affiliation: Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany. helge.mueller@uk-erlangen.de
authors.forename: W
authors.initials: W
authors.lastname: Sperling
authors.forename: H
authors.initials: H
authors.lastname: Müller
mesh_terms: D000342:Affective Symptoms / Q000378:metabolism; D001712:Biperiden / Q000494:pharmacology; D001921:Brain / Q000473:pathology*; D003342:Corpus Striatum / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation; D001523:Mental Disorders / Q000175:diagnosis*; D008954:Models, Biological; D008962:Models, Theoretical; D009422:Nervous System Diseases / Q000175:diagnosis; D011570:Psychiatry / Q000379:methods
chemical_list: D001712:Biperiden