title: Risk factors of dengue shock syndrome in children.
abstract: This retrospective hospital-based study was conducted to evaluate the various risk factors associated with dengue shock syndrome (DSS) in patients (≤18 years of age) of dengue hemorrhagic fever (DHF). Medical records of these 483 patients with DHF (IgM serology positive) were analyzed with reference to shock for various clinical and biochemical parameters. Of the 483 children, 405 were categorized in DHF group (grade I, 282 children; grade II, 123 children) and 78 in DSS group (grade III, 59 children; grade IV, 19 children). Using univariate and multivariate logistic regression and p-value of <0.05 as significant, the presence of spontaneous bleeding, hepatomegaly, signs of capillary leakage like ascitis and pleural effusion, leucopenia <4000 mm(3) and age >5 years were found out to be significant risk factors of shock in pediatrics patients of DHF.
authors.affiliation: Department of Pediatrics, PGIMER and associated Dr Ram Manohar Lohia Hospital, New Delhi, India. yzaygupta@gmail.com
authors.forename: Vijay
authors.initials: V
authors.lastname: Gupta
authors.forename: Tribhuvan Pal
authors.initials: TP
authors.lastname: Yadav
authors.forename: Ravindra Mohan
authors.initials: RM
authors.lastname: Pandey
authors.forename: Aaradhna
authors.initials: A
authors.lastname: Singh
authors.forename: Meetu
authors.initials: M
authors.lastname: Gupta
authors.forename: Pradeep
authors.initials: P
authors.lastname: Kanaujiya
authors.forename: Arti
authors.initials: A
authors.lastname: Sharma
authors.forename: Vivek
authors.initials: V
authors.lastname: Dewan
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D019595:Severe Dengue / Q000209:etiology* / Q000503:physiopathology