title: Immortalization of human B-lymphocytes by epstein-barr virus.
abstract: Epstein-Barr virus (EBV) is able to immortalize human B-lymphocytes with high efficiency. This property underlies the role of EBV in a number of human diseases. First, EBV is the causative agent of infectious mononucleosis, which is a benign proliferation of B-lymphocytes (1). Second, EBV is involved in the etiology of Burkitt's lymphoma (2) and of invasive B-lymphocyte proliferations found in immunosuppressed individuals (3).
authors.affiliation: Medical Molecular Biology Unit, University College and Middlesex School of Medicine, London, UK.
authors.forename: P M
authors.initials: PM
authors.lastname: Brickell