title: Pulmonary thromboembolism as the initial manifestation in a child with antiphospholipid syndrome in the emergency department.
abstract: Antiphospholipid syndrome is characterized by recurrent arterial or venous thrombosis at any level of the vascular tree and the presence of circulating antiphospholipid antibodies. The syndrome may be idiopathic or secondary to an underlying autoimmune disorder. The disease is uncommon in children, and manifestations are diverse and underreported. We report the case of a 10-year-old boy who presented with features of pulmonary thromboembolism in the emergency department. Subsequently, he proved to have systemic lupus erythematosus with circulating antiphospholipid antibodies. He had no signs of systemic lupus erythematosus at presentation. In conclusion, antiphospholipid syndrome should also be kept as a possibility in children presenting for the first time with pulmonary thromboembolism in the emergency department.
authors.affiliation: Department of Pediatrics, Sheri-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India. mbhat47@rediffmail.com
authors.forename: Mushtaq Ahmad
authors.initials: MA
authors.lastname: Bhat
authors.forename: Umer Amin
authors.initials: UA
authors.lastname: Qureshi
authors.forename: Syed Wajid
authors.initials: SW
authors.lastname: Ali
authors.forename: Javeed Iqbal
authors.initials: JI
authors.lastname: Bhat
authors.forename: Natasha
authors.initials: N
authors.lastname: Din
authors.forename: Irfan
authors.initials: I
authors.lastname: Robbani
mesh_terms: D000792:Angiography / Q000379:methods; D017152:Antibodies, Antiphospholipid / Q000097:blood; D000925:Anticoagulants / Q000008:administration & dosage; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D002648:Child; D005500:Follow-Up Studies; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D015278:Intensive Care Units, Pediatric; D008297:Male; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D017152:Antibodies, Antiphospholipid; D000925:Anticoagulants; D006493:Heparin