title: DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker.
abstract: Nucleic acid templated reactions have attracted significant attention for nucleic acid sensing. Herein we report a general design which extends the potential of nucleic acid templated reactions to unleash the function of a broad diversity of small molecules such as a transcription factor agonist, a cytotoxic or a fluorophore.
authors.affiliation: Institut de Science et Ingenierie Supramoleculaires (ISIS), Université de Strasbourg-CNRS (UMR 7006), 8 allee Gaspard Monge, 67000 Strasbourg, France.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Gorska
authors.forename: Alex
authors.initials: A
authors.lastname: Manicardi
authors.forename: Sofia
authors.initials: S
authors.lastname: Barluenga
authors.forename: Nicolas
authors.initials: N
authors.lastname: Winssinger
mesh_terms: D001386:Azides / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D015195:Drug Design; D007700:Kinetics; D010084:Oxidation-Reduction
chemical_list: D001386:Azides; D004247:DNA