title: Multipotent adult progenitor cells.
abstract: We here discuss the potency and characteristics of various adult derived adherent stem cells with special focus on multipotent adult progenitor cells (MAPC) isolated first in 2002 in our lab. We describe the potency of MAPC, our current understanding in relationship with novel insights gained in epigenetic modifications that increase cellular potency, and their possible clinical applications.
authors.affiliation: Interdepartementaal Stamcelinstituut, Katholieke Universiteit Leuven, O&N1, bus 804, Herestraat 49, 3000 Leuven, Belgium. Abhishek.Sohni@med.kuleuven.be
authors.forename: Abhishek
authors.initials: A
authors.lastname: Sohni
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Verfaillie
mesh_terms: D053687:Adult Stem Cells / Q000502:physiology*; D000818:Animals; D053595:Embryonic Stem Cells / Q000502:physiology; D057890:Epigenomics; D006801:Humans; D051379:Mice; D039902:Multipotent Stem Cells / Q000502:physiology*; D051381:Rats; D057905:Stem Cell Research / Q000941:ethics; D014327:Trophoblasts / Q000166:cytology