title: [Subarachnoid hemorrhages form ruptured aneurysms as the presenting feature of lupus cerebral vasculitis].
abstract: Cerebral aneurysms secondary to cerebral vasculitis related to systemic lupus erythematosus are rare. We report a 31-year-old woman who presented with a lupus flare associated with inaugural generalized seizures. Computed tomography angiography showed subarachnoid hemorrhage by rupture of a cerebellar artery fusiform aneurysm. Later, despite the initiation of corticosteroids and cyclophosphamide, she presented a second cerebral hemorrhage due to the rupture of a new aneurysm in lenticulostriates arteries. The outcome was fatal. We discuss the frequency and management of this severe complication of systemic lupus erythematosus.
authors.affiliation: Service de médecine interne, hôpital universitaire de la Conception, 147, boulevard Baille, 13005 Marseille, France.
authors.forename: S
authors.initials: S
authors.lastname: Brah
authors.forename: G
authors.initials: G
authors.lastname: Thomas
authors.forename: F
authors.initials: F
authors.lastname: Chapon
authors.forename: J
authors.initials: J
authors.lastname: Franques
authors.forename: N
authors.initials: N
authors.lastname: Jourde
authors.forename: J-R
authors.initials: JR
authors.lastname: Harlé
authors.forename: J-M
authors.initials: JM
authors.lastname: Durand
authors.forename: R
authors.initials: R
authors.lastname: Jean
authors.forename: L
authors.initials: L
authors.lastname: Chiche
mesh_terms: D000328:Adult; D017542:Aneurysm, Ruptured / Q000175:diagnosis / Q000209:etiology*; D002533:Cerebral Angiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D020945:Lupus Vasculitis, Central Nervous System / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D012422:Rupture, Spontaneous; D012640:Seizures / Q000209:etiology; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000209:etiology*