title: Tandem catalysis: from alkynoic acids and aryl iodides to 1,2,3-triazoles in one pot.
abstract: A tandem catalysis protocol based on decarboxylative coupling of alkynoic acids and 1,3-dipolar cycloaddition of azides enables a highly efficient synthesis of a variety of functionalized 1,2,3-triazoles. The three-step, one-pot method avoids usage of gaseous or highly volatile terminal alkynes, reduces handling of potentially unstable and explosive azides to a minimum, and furnishes target structures in excellent yields and a very good purity without the need for additional purification.
authors.affiliation: Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology, Radlinského 9, 81237 Bratislava, Slovak Republic. andrej.kolarovic@stuba.sk
authors.forename: Andrej
authors.initials: A
authors.lastname: Kolarovič
authors.forename: Michael
authors.initials: M
authors.lastname: Schnürch
authors.forename: Marko D
authors.initials: MD
authors.lastname: Mihovilovic