title: Recombinant-adeno-associated viral vector-mediated gene therapy for cardiovascular diseases.
abstract: Adeno-associated virus is a kind of DNA defective parvovirus which is non-pathogenic. Recombinant-adeno-associated virus vector comes from wild-type non-pathogenic adeno-associated virus and is highly secure, and it also has the advantages of broad host range. Recombinant-adeno-associated virus vector has become a hot spot for gene therapy and is widely used in gene therapy for cardiovascular diseases, especially for hypertension, heart failure, arteriosclerosis, and myocardial infarction.
authors.affiliation: Center of Clinical Pharmacology, Third Xiangya Hospital, School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
authors.forename: Meizhen
authors.initials: M
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Yuan
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Huang
authors.forename: Fang
authors.initials: F
authors.lastname: Hu
mesh_terms: D001161:Arteriosclerosis / Q000628:therapy; D002318:Cardiovascular Diseases / Q000628:therapy*; D000229:Dependovirus / Q000235:genetics* / Q000378:metabolism; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors; D006333:Heart Failure / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000628:therapy; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000235:genetics
chemical_list: D011994:Recombinant Proteins