title: Comparison of different surgical approaches in T2 glottic cancer.
abstract: BACKGROUND
  The purpose of this study was to evaluate retrospectively the oncologic results of endoscopic and open surgical techniques in treating T2 glottic carcinomas.
  
  
  METHODS
  The medical chart of 354 patients with T2 glottic cancer managed with primary surgery were reviewed. Laser microsurgery and frontolateral partial laryngectomy were compared for disease-specific survival and local control rates, incidence of major complications, and related tracheostomies. Additionally, the influence of the anterior commissure invasion on these oncologic parameters was evaluated.
  
  
  RESULTS
  No statistically significant differences were found between the surgical procedures regarding our oncologic parameters. A lower incidence of tracheotomies and complications were comparatively found for laser surgery. Tumor invasion of the anterior commissure did not seem to influence the oncologic results.
  
  
  CONCLUSIONS
  Transoral surgery seems to be the treatment of choice for T2 glottic cancer. In our view, open partial laryngectomy should be reserved for those cases in which the lesion cannot be adequately exposed by direct microlaryngoscopy.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen - Nuremberg Medical School, Germany.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Mantsopoulos
authors.forename: Georgios
authors.initials: G
authors.lastname: Psychogios
authors.forename: Michael
authors.initials: M
authors.lastname: Koch
authors.forename: Johannes
authors.initials: J
authors.lastname: Zenk
authors.forename: Frank
authors.initials: F
authors.lastname: Waldfahrer
authors.forename: Heinrich
authors.initials: H
authors.lastname: Iro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005931:Glottis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D053208:Kaplan-Meier Estimate; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects / Q000379:methods*; D007828:Laryngoscopy / Q000009:adverse effects / Q000379:methods*; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications; D012189:Retrospective Studies; D016019:Survival Analysis