title: Evaluation of spinal mobility measurements in predicting axial psoriatic arthritis.
abstract: Axial psoriatic arthritis (PsA) represents a more severe form of disease than peripheral PsA. We evaluate the usefulness of various spinal mobility measurements in predicting a radiographically defined axial PsA. A cross-sectional study on PsA patients with spinal mobility measurement performed. PsA were classified to axial or peripheral PsA by the presence of sacroiliitis. Three Bath Ankylosing Spondylitis Metrology Indexes (BASMIs) were calculated. The sensitivity, specificity, and area under receiver operator curves (AUC) of each spinal mobility measurement in prediction of axial PsA were analyzed. A total of 125 subjects studied (males 52%) with mean age and duration of illness of 47.5 ± 12.4 and 9.2 ± 6.7 years. Twenty-nine patients (17 males and duration of illness 12 females) had axial PsA. Axial PsA patients had longer disease duration (p = 0.05) and more limitation in spinal mobility. Axial PsA patients had higher inflammatory markers and a trend towards poorer global health, higher damaged joint count, and poorer physical function. The tragus-to-wall distance, modified schober test, and lumber side flexion had good sensitivity and specificity in predicting axial PsA. In the logistic regression model, the lumbar side flexion (OR 0.82, 95% CI 0.72-0.92) was independently associated with axial PsA. All three sets of composite scores BASMI(2), BASMI(10), and BASMI (lin) had good prediction for axial PsA (AUC 0.619, 0.626, and 0.618). Spinal mobility measurements and BASMI were useful in differentiating axial and peripheral PsA. Lumber side flexion and modified schober test best differentiate axial and peripheral PsA.
authors.affiliation: Department of Medicine & Geriatrics, Tai Po Hospital, 9 Chuen On Road, Tai Po, NT, Hong Kong SAR, China. katyccc@hotmail.com
authors.forename: Ying-ying
authors.initials: YY
authors.lastname: Leung
authors.forename: Kwok Wah
authors.initials: KW
authors.lastname: Ho
authors.forename: Lai Shan
authors.initials: LS
authors.lastname: Tam
authors.forename: Tracy Y
authors.initials: TY
authors.lastname: Zhu
authors.forename: Lai W
authors.initials: LW
authors.lastname: Kwok
authors.forename: Tena K
authors.initials: TK
authors.lastname: Li
authors.forename: Emily W
authors.initials: EW
authors.lastname: Kun
authors.forename: Edmund K
authors.initials: EK
authors.lastname: Li
mesh_terms: D015535:Arthritis, Psoriatic / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D001175:Arthrography; D005260:Female; D006801:Humans; D007596:Joints / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009068:Movement; D016059:Range of Motion, Articular; D012720:Severity of Illness Index; D013122:Spinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D013131:Spine / Q000503:physiopathology*