title: Production of haloduracin by Bacillus halodurans using solid-state fermentation.
abstract: Bacillus halodurans was cultivated on wheat bran as a solid-state substrate and produced haloduracin, a bacteriocin, at about 245 AU per wheat bran. Supplementation of the bran with Lauria-Bertani broth decreased haloduracin production. However, production was stimulated by addition of Mg(2)SO(4) and K(2)HPO(4). The highest production was achieved at a wheat bran/moisture ratio of 1:1.8 and in the presence of 10% (w/w) Na(2)CO(3). Under optimum conditions, the organism produced about 3,000 AU per gram dry bran.
authors.affiliation: Department of Biotechnology, Lund University, Lund, Sweden.
authors.forename: Abolghasem
authors.initials: A
authors.lastname: Danesh
authors.forename: Gashaw
authors.initials: G
authors.lastname: Mamo
authors.forename: Bo
authors.initials: B
authors.lastname: Mattiasson
mesh_terms: D001407:Bacillus / Q000378:metabolism*; D001430:Bacteriocins / Q000378:metabolism*; D003470:Culture Media / Q000737:chemistry*; D004043:Dietary Fiber / Q000378:metabolism; D005285:Fermentation; D008278:Magnesium Sulfate / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D017680:Potassium Compounds / Q000378:metabolism
chemical_list: D001430:Bacteriocins; D003470:Culture Media; D004043:Dietary Fiber; D010710:Phosphates; D017680:Potassium Compounds; C515824:haloduracin, Bacillus halodurans; D008278:Magnesium Sulfate; C013216:potassium phosphate