title: Characterization of Candida species from different populations in Taiwan.
abstract: The opportunistic Candida species existing as part of commensal microbiota in humans are usually the etiological agents causing infections. We investigated whether isolates collected from different age groups, hospital units, and sources have distinct characteristics. A total of 913 isolates comprising 395 Candida albicans, 230 Candida tropicalis, 202 Candida glabrata, 62 Candida parapsilosis, 13 Candida krusei, and 11 of other six species were analyzed. Urine was the most common source (41.2%), followed by sputum (16.3%), blood (15.2%), and others (27.3%). Candida albicans and C. parapsilosis were more prevalent in the working group [from 19 to 65 years], whereas C. tropicalis and C. glabrata were more prevalent in the elder one (≥ 66 years). We found that the age of patients and the source of isolates affect the distribution of species. On the other hand, the drug susceptibility of isolates was associated with fungal species and whether patients were hospitalized.
authors.affiliation: Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
authors.forename: Yun-Liang
authors.initials: YL
authors.lastname: Yang
authors.forename: Li-Yun
authors.initials: LY
authors.lastname: Hsieh
authors.forename: An-Huei
authors.initials: AH
authors.lastname: Wang
authors.forename: Hsiu-Jung
authors.initials: HJ
authors.lastname: Lo
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000494:pharmacology; D012634:Bodily Secretions / Q000382:microbiology; D002175:Candida / Q000145:classification* / Q000302:isolation & purification*; D002353:Carrier State / Q000382:microbiology*; D018594:Human Body; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013624:Taiwan; D055815:Young Adult
chemical_list: D000935:Antifungal Agents