title: [Prediction of adherence of patients with schizophrenia to treatment regime after a discharge from a hospital].
abstract: We studied 215 patients with schizophrenia discharged from a psychiatric hospital. Every 5th patient reported missing the treatment with psychotropic drugs for one week or longer during 3 months after the discharge. Respectively, two groups of patients were singled out: non-compliant (42 people, 19,8%) and compliant (173, 80,2%). The logistic regression analysis revealed three independent variables correlated with the non-compliancy: past abuse of psychoactive drugs, past non-adherence to treatment regime and family refusal to be involved in control of treatment, with the risk estimated for each factor as 4,6 (95% CI 1,7-12,0); 4,1 (95% CI 1,3-12,2) and 3,4 (95% CI 1,1-10,3), respectively. The low level of optimism was significantly associated with non-compliance (OR=1,5; 95% CI 1,1-2,0). These results may promote the timely identification of at-risk patients after their discharge from hospital that will allow timely correction of pharmacological and targeted psychosocial assistance to this group of patients augmenting their motivation to continue the treatment.
authors.forename: I A
authors.initials: IA
authors.lastname: Bylim
authors.forename: E B
authors.initials: EB
authors.lastname: Liubov
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D010349:Patient Compliance; D010351:Patient Discharge; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D057566:Self Report
chemical_list: D011619:Psychotropic Drugs