title: Deeper rectal biopsies and better yield of neuronal structures with Scheye vs Noblett forceps--preliminary results.
abstract: OBJECTIVE
  The aim of the study was to compare 2 different forceps designed to perform biopsies of the rectal mucosa, those of Noblett and Scheye, the latter having a similar design and differing by the disposable cutting system.
  
  
  METHODS
  This historical study compares biopsies obtained with the Noblett forceps in 13 girls and 20 boys (mean ± SD age, 13 ± 30 months) and biopsies obtained with the Scheye forceps in 19 girls and 21 boys (mean ± SD age, 8.5 ± 19 months).
  
  
  RESULTS
  The thickness of the material obtained with the Scheye forceps was significantly greater for the specimens obtained with the Scheye forceps (total biopsy: 1.74 ± 0.46 mm vs 0.67 ± 0.2 mm, P < .0001; submucosa: 1.12 ± 0.4 mm vs 0.14 ± 0.17 mm, P < .001). The Scheye forceps considerably increased the yield of neuronal structures, both for submucosal plexus (P < .003) and ganglia (P < .0001). No complication occurred in either group.
  
  
  CONCLUSIONS
  The Scheye disposable rectal biopsy system provides larger mucosal biopsy samples than the Noblett with increased recovery of neuronal structures.
authors.affiliation: Service de Gastroentérologie pédiatrique, Hôpital St Vincent de Paul, APHP, Université Paris-Descartes, Paris, France. florence.campeotto@svp.aphp.fr
authors.forename: Florence
authors.initials: F
authors.lastname: Campeotto
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Barbet
authors.forename: Nicolas
authors.initials: N
authors.lastname: Kalach
authors.forename: Pierre
authors.initials: P
authors.lastname: Arhan
authors.forename: Ghislain
authors.initials: G
authors.lastname: Devroede
authors.forename: Sylvie
authors.initials: S
authors.lastname: Beaudoin
authors.forename: Christophe
authors.initials: C
authors.lastname: Dupont
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods; D002675:Child, Preschool; D003248:Constipation / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D004867:Equipment Design; D005260:Female; D005725:Ganglia, Autonomic / Q000473:pathology*; D006627:Hirschsprung Disease / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000294:innervation / Q000473:pathology; D008297:Male; D012007:Rectum / Q000294:innervation / Q000473:pathology*; D012189:Retrospective Studies; D016037:Single-Blind Method; D013368:Submucous Plexus / Q000473:pathology*; D013525:Surgical Instruments