title: [A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma].
abstract: We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective. The patient was a 28-year-old female who developed abdominal pain caused by peritoneal dissemination on postoperative day 60 after radical hysterectomy and colostomy. For pain relief, administration of 10-mg slow-release oxycodone and 180-mg loxoprofen sodium was begun. When the dose was increased to 25 mg on postoperative day 240, the slow-release oxycodone in its original form was confirmed in feces from the artificial anus.When the same drug was changed to a fentanyl patch(12. 5 mg/hr), the pain was relieved. A palliative care doctor needs much knowledge regarding the changes in the patient's body with the progress and treatment of cancer, in addition to the drug mechanism.
authors.affiliation: Dept. of Thoracic Surgery, Tokai University School of Medicine.
authors.forename: Kazuho
authors.initials: K
authors.lastname: Yoshino
authors.forename: Noboru
authors.initials: N
authors.lastname: Nishiumi
authors.forename: Ryota
authors.initials: R
authors.lastname: Masuda
authors.forename: Yuki
authors.initials: Y
authors.lastname: Saito
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iwazaki
authors.forename: Mikio
authors.initials: M
authors.lastname: Mikami
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tokuda
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D002277:Carcinoma / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007078:Ileal Neoplasms / Q000556:secondary*; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010166:Palliative Care; D010534:Peritoneal Neoplasms / Q000556:secondary
chemical_list: D005283:Fentanyl