title: Nutritional status of iodine in pregnant women in Catalonia (Spain): study on hygiene-dietetic habits and iodine in urine.
abstract: BACKGROUND
  It is a priority to achieve an adequate nutritional status of iodine during pregnancy since iodine deficiency in this population may have repercussions on the mother during both gestation and post partum as well as on the foetus, the neonate and the child at different ages. According to the WHO, iodine deficiency is the most frequent cause of mental retardation and irrreversible cerebral lesions around the world. However, few studies have been published on the nutritional status of iodine in the pregnant population within the Primary Care setting, a health care level which plays an essential role in the education and control of pregnant women. Therefore, the aim of the present study is: 1.- To know the hygiene-dietetic habits related to the intake of foods rich in iodine and smoking during pregnancy. 2.- To determine the prevalence of iodine deficiency and the factors associated with its appearance during pregnancy.
  
  
  METHODS
  We will perform a cluster randomised, controlled, multicentre trial. Randomisation unit: Primary Care Team.
  
  
  METHODS
  898 pregnant women over the age of 17 years attending consultation to a midwife during the first trimester of pregnancy in the participating primary care centres.
  
  
  METHODS
  consumption of iodine-rich foods and iodine deficiency. Points of assessment: each trimester of the gestation.
  
  
  METHODS
  group education during the first trimester of gestation on healthy hygiene-dietetic habits and the importance of an adequate iodine nutritional status.
  
  
  METHODS
  descriptive analysis of all variables will be performed as well as multilevel logistic regression. All analyses will be done carried out on an intention to treat basis and will be fitted for potential confounding factors and variables of clinical importance.
  
  
  CONCLUSIONS
  Evidence of generalised iodine deficiency during pregnancy could lead to the promotion of interventions of prevention such as how to improve and intensify health care educational programmes for pregnant women.
  
  
  BACKGROUND
  ClinicalTrials.gov: NCT01301768.
authors.affiliation: Gerencia de Atención Primaria, Avenida Portugal 47, 05004 Ávila, Spain.
authors.forename: Gemma
authors.initials: G
authors.lastname: Prieto
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Torres
authors.forename: Lidia
authors.initials: L
authors.lastname: Francés
authors.forename: Gemma
authors.initials: G
authors.lastname: Falguera
authors.forename: Lluis
authors.initials: L
authors.lastname: Vila
authors.forename: Josep María
authors.initials: JM
authors.lastname: Manresa
authors.forename: Roser
authors.initials: R
authors.lastname: Casamitjana
authors.forename: Juan Ramón
authors.initials: JR
authors.lastname: Barrada
authors.forename: Amèlia
authors.initials: A
authors.lastname: Acera
authors.forename: Dolors
authors.initials: D
authors.lastname: Guix
authors.forename: Anna
authors.initials: A
authors.lastname: Torrent
authors.forename: Josep
authors.initials: J
authors.lastname: Grau
authors.forename: Pere
authors.initials: P
authors.lastname: Torán
mesh_terms: D000293:Adolescent; D000328:Adult; D004032:Diet; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D007455:Iodine / Q000172:deficiency*; D016015:Logistic Models; D018977:Micronutrients / Q000172:deficiency*; D009752:Nutritional Status; D011247:Pregnancy; D015995:Prevalence; D011320:Primary Health Care / Q000706:statistics & numerical data*; D012107:Research Design; D012907:Smoking; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
chemical_list: D018977:Micronutrients; D007455:Iodine