title: The evolution of transapical aortic valve implantation and new perspectives.
abstract: Transapical aortic valve implantation (TA-AVI) is a truly minimally invasive technique allowing for off-pump aortic valve implantation in selected high-risk patients. Potential advantages are the avoidance of cardiopulmonary bypass, cross-clamping and sternotomy. Compared to transfemoral aortic valve implantation the current strengths of the transapical approach are the avoidance of the femoral arteries as well as a very low stroke risk due to minimal manipulations in the aortic arch. TA-AVI has evolved to a routine procedure in selected specialized centers providing a safe and reproducible treatment option for high-risk elderly patients suffering from severe symptomatic aortic stenosis.
authors.affiliation: Department of Cardiac Surgery, Kerckhoff-Klinik Bad Nauheim, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Kempfert
authors.forename: Arnaud
authors.initials: A
authors.lastname: Van Linden
authors.forename: David
authors.initials: D
authors.lastname: Holzhey
authors.forename: Ardawan
authors.initials: A
authors.lastname: Rastan
authors.forename: Johannes
authors.initials: J
authors.lastname: Blumenstein
authors.forename: Friedrich W
authors.initials: FW
authors.lastname: Mohr
authors.forename: Thomas
authors.initials: T
authors.lastname: Walther
mesh_terms: D001021:Aortic Valve / Q000473:pathology*; D001024:Aortic Valve Stenosis / Q000628:therapy*; D002404:Catheterization / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D006801:Humans; D018570:Risk Assessment