title: Direct synthesis of ester-containing indium homoenolate and its application in palladium-catalyzed cross-coupling with aryl halide.
abstract: An efficient method for the synthesis of ester-containing indium homoenolate via a direct insertion of indium into β-halo ester in the presence of CuI/LiCl was described. The synthetic utility of the indium homoenolate was demonstrated by palladium-catalyzed cross-coupling with aryl halides in DMA with wide functional group compatibility.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.
authors.forename: Zhi-Liang
authors.initials: ZL
authors.lastname: Shen
authors.forename: Kelvin Kau Kiat
authors.initials: KK
authors.lastname: Goh
authors.forename: Colin Hong An
authors.initials: CH
authors.lastname: Wong
authors.forename: Yong-Sheng
authors.initials: YS
authors.lastname: Yang
authors.forename: Yin-Chang
authors.initials: YC
authors.lastname: Lai
authors.forename: Hao-Lun
authors.initials: HL
authors.lastname: Cheong
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D007204:Indium / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D018021:Lithium Chloride / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004952:Esters; D007454:Iodides; D009942:Organometallic Compounds; D007204:Indium; D010165:Palladium; D003300:Copper; C073870:cuprous iodide; D018021:Lithium Chloride