title: The association of gastroschisis with other congenital anomalies: how important is it?
abstract: OBJECTIVE
  To report the prevalence of the association between gastroschisis and other anomalies, their prenatal characteristics and the postnatal follow-up.
  
  
  METHODS
  Prenatal and postnatal data from all patients with gastroschis prenatally diagnosed between January 1998 and December 2006 were reviewed concerning the presence of associated anomalies.
  
  
  RESULTS
  Gastroschisis was prenatally diagnosed in 108 fetuses. Associated anomalies were identified in 14 cases (prevalence of 13.0%), with prenatal diagnosis being made in 5 (35.7%) patients. Postnatal examination revealed the association of other anomalies in nine other newborns not observed during prenatal examinations. Maternal age, parity, gestational age at diagnosis and birth, delivery mode and birth weight were similar in cases with 'isolated gastroschisis' and associated anomalies (p > 0.05). Survival rates in the 'isolated gastroschisis group' and 'associated anomaly group' were 91.5 and 78.6% (p > 0.05), respectively. The median time before oral feeding tended to be longer (but not statistical significantly) in the 'associated anomaly group' (32, range: 5-720 days) compared to the 'isolated gastroschisis group' (22, range: 5-180 days; p = 0.06), but with a significantly longer permanence in neonatal intensive care unit (p = 0.04).
  
  
  CONCLUSIONS
  This study highlights the importance of identifying other anomalies when evaluating fetuses with gastroschisis to permit counselling concerning the postnatal outcomes.
authors.affiliation: Maternité, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Ruano
authors.forename: Olivier
authors.initials: O
authors.lastname: Picone
authors.forename: Lisandra
authors.initials: L
authors.lastname: Bernardes
authors.forename: Jelena
authors.initials: J
authors.lastname: Martinovic
authors.forename: Yves
authors.initials: Y
authors.lastname: Dumez
authors.forename: Alexandra
authors.initials: A
authors.lastname: Benachi
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D020139:Gastroschisis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007902:Length of Stay; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies; D055815:Young Adult