title: GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns.
abstract: GO-Module is a web-accessible synthesis and visualization tool developed for end-user biologists to greatly simplify the interpretation of prioritized Gene Ontology (GO) terms. GO-Module radically reduces the complexity of raw GO results into compact biomodules in two distinct ways, by (i) constructing biomodules from significant GO terms based on hierarchical knowledge, and (ii) refining the GO terms in each biomodule to contain only true positive results. Altogether, the features (biomodules) of GO-Module outputs are better organized and on average four times smaller than the input GO terms list (P = 0.0005, n = 16).
  
  
  BACKGROUND
  http://lussierlab.org/GO-Module.
authors.affiliation: Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, the University of Chicago, Chicago, IL, USA.
authors.forename: Xinan
authors.initials: X
authors.lastname: Yang
authors.forename: Jianrong
authors.initials: J
authors.lastname: Li
authors.forename: Younghee
authors.initials: Y
authors.lastname: Lee
authors.forename: Yves A
authors.initials: YA
authors.lastname: Lussier
mesh_terms: D005796:Genes; D020407:Internet; D012984:Software; D009626:Terminology as Topic; D014584:User-Computer Interface; D018875:Vocabulary, Controlled