title: Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis.
abstract: Presentation of cystic fibrosis (CF) with an acrodermatitis enteropathica-like skin rash, anemia, and hypoproteinemia without pulmonary disease is rarely reported before. We describe an 11-month-old boy with rash and edema as the presenting signs of cystic fibrosis. The interesting additional finding in our patient was the graying hair after 3 months of age. A reversal of the gray hair was observed by pancreatic enzyme replacement therapy. In conclusion, acrodermatitis-like eruption and hypoproteinemia can be a presenting sign of CF. Graying hair has not been noticed so far as a sign of CF in these patients.
authors.affiliation: Department of Pediatric Gastroenterology, Gazi University School of Medicine, Ankara, Turkey.
authors.forename: Buket
authors.initials: B
authors.lastname: Dalgic
authors.forename: Odul
authors.initials: O
authors.lastname: Egritas
mesh_terms: D000169:Acrodermatitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D018798:Anemia, Iron-Deficiency / Q000209:etiology; D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D003872:Dermatitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D056947:Enzyme Replacement Therapy; D005076:Exanthema / Q000209:etiology; D006200:Hair Color / Q000187:drug effects; D006801:Humans; D007019:Hypoproteinemia / Q000209:etiology; D007223:Infant; D008297:Male; D016896:Treatment Outcome; D015032:Zinc / Q000172:deficiency
chemical_list: D015032:Zinc