title: [Outcome post orthotopic heart transplantation for patients with end-stage hypertrophic cardiomyopathy].
abstract: OBJECTIVE
  To investigate the outcome of orthotopic heart transplantation for patient with end-stage hypertrophic cardiomyopathy.
  
  
  METHODS
  This retrospective review analyzed the clinical data of nine patients (7 males) undergoing orthotopic heart transplantation for end-stage hypertrophic cardiomyopathy in our center. All patients received induced therapy protocols peri-operative and standard triple maintenance immunosuppressive therapy postoperative.
  
  
  RESULTS
  One recipients developed acute renal failure due to renal artery embolism and allograft rejection in the early posttransplantive course, symptoms and signs were improved under continuous renal replacement therapy and steroid-pulse therapy, this patient died of sudden cardiac arrest at 32 months post transplantation. Another recipient developed demyelinating disease in frontal and parietal lobe and finally recovered with medical therapy. Eight patients survived the operation with good quality of life and there was no episode of rejection or infection or chronic graft arteriosclerosis during follow-up time. Three recipients developed left ventricular hypertrophy and there were no signs of grapg-vessel diseases in the survivals.
  
  
  CONCLUSIONS
  Heart transplantation is the best therapeutic option for selected patients with end-stage hypertrophic cardiomyopathy.
authors.affiliation: Department of Cardiac Surgery, Fujian Medical University, Fuzhou 350001, China. drhxs@163.com
authors.forename: Xue-shan
authors.initials: XS
authors.lastname: Huang
authors.forename: Liang-wan
authors.initials: LW
authors.lastname: Chen
authors.forename: Yu-chen
authors.initials: YC
authors.lastname: Pan
authors.forename: Feng
authors.initials: F
authors.lastname: Lin
authors.forename: Qi-min
authors.initials: QM
authors.lastname: Wang
authors.forename: Zhong-yao
authors.initials: ZY
authors.lastname: Huang
authors.forename: Han-fan
authors.initials: HF
authors.lastname: Qiu
authors.forename: Hua
authors.initials: H
authors.lastname: Cao
authors.forename: Gui-can
authors.initials: GC
authors.lastname: Zhang
authors.forename: Dao-zhong
authors.initials: DZ
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000601:surgery*; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult