title: Digital magnification mammography with matched incident exposure: physical imaging properties and detectability of simulated microcalcifications.
abstract: Our purpose was to evaluate the usefulness of digital magnification mammography with matched incident exposure by investigating the physical imaging properties and doing an observer performance test. A computed radiography system and a mammographic unit were used in this study. Contact and magnification radiographies of 1.2-1.8 in combination with focal spot sizes of 0.1 mm without grid and 0.3 mm with grid were performed. Physical imaging properties, namely, scatter fraction, total modulation transfer function (MTF) including the presampled MTF and the MTF of focal spot size, and Wiener spectrum (WS), were measured. Detail visibility was evaluated by use of free-response receiver operating characteristic analysis of the detectability of simulated microcalcifications. Scatter fractions decreased considerably as the magnification factor increased without grid technique. In the grid technique, scatter fractions for all magnification techniques were comparable. The total MTFs of magnification techniques with a focal spot size of 0.1 mm improved significantly compared with the conventional contact technique. However, the improvement of the total MTFs of magnification techniques with the combination of 0.3 mm focal spot size was small. The WSs degraded with an increase of the magnification factor compared with the contact technique due to the maintained exposure incident on the object. The observer performance test indicated that the 1.8 magnification technique with the 0.1 mm focal spot size provided higher detectability than did the contact technique. Digital magnification mammography under the same incident exposure conditions improved the detectability of microcalcifications.
authors.affiliation: Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi-ku, Fukuoka, Japan. nobukazu.tanaka@gmail.com
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kentaro
authors.initials: K
authors.lastname: Naka
authors.forename: Hiroko
authors.initials: H
authors.lastname: Fukushima
authors.forename: Junji
authors.initials: J
authors.lastname: Morishita
authors.forename: Fukai
authors.initials: F
authors.lastname: Toyofuku
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ohki
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Higashida
mesh_terms: D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008327:Mammography / Q000295:instrumentation / Q000379:methods*; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000379:methods*; D011858:Radiographic Magnification / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity