title: New pregnane glycosides from Brucea javanica and their antifeedant activity.
abstract: Three new pregnane glycosides, 3-O-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol (1), 3-O-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol-20-O-β-D-glucopyranoside (2), 3-O-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol-20-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (3) were isolated along with four known compounds, 4-7, from the leaves and stems of Brucea javanica. Their structures were determined by detailed analyses of 1D- and 2D-NMR spectroscopic data. All of the compounds isolated from Brucea javanica were tested for the antifeedant activities against the larva of Pieris rapae. Compounds 1, 3, and 5 showed significant antifeedant activities after 72 h incubation.
authors.affiliation: Department of Phytochemistry, Guangxi Institute of Botany, Guangxi Zhuangzu Autonomous Region and Chinese Academy of Sciences, Guilin 541006, P R China.
authors.forename: Yue-Yuan
authors.initials: YY
authors.lastname: Chen
authors.forename: Qiao-Dan
authors.initials: QD
authors.lastname: Pan
authors.forename: Dian-Peng
authors.initials: DP
authors.lastname: Li
authors.forename: Jin-Lei
authors.initials: JL
authors.lastname: Liu
authors.forename: Yong-Xin
authors.initials: YX
authors.lastname: Wen
authors.forename: Yong-Lin
authors.initials: YL
authors.lastname: Huang
authors.forename: Feng-Lai
authors.initials: FL
authors.lastname: Lu
mesh_terms: D000818:Animals; D001067:Appetite Depressants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D032269:Brucea / Q000737:chemistry*; D002080:Butterflies / Q000187:drug effects*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects*; D015394:Molecular Structure; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013237:Stereoisomerism
chemical_list: D001067:Appetite Depressants; D006027:Glycosides; D011278:Pregnanes