title: [Outcome after treatment of myopia with implantable Collamer lens].
abstract: OBJECTIVE
  To evaluate the efficacy, predictability, stability, and safety of the surgical correction myopia using implantable Collamer lenses (ICL) in phakic eyes.
  
  
  METHODS
  A prospective study was performed to analyze 91 eyes of 48 patients who had the implantation of ICL for the treatment of myopia from July 2008 to February 2010. Patients were examined preoperatively and followed at 1 week, 1, 3, 6, and 12 months postoperatively. The examinations included the uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refraction, contrast sensitivity, wavefront aberration, intraocular pressure, space between crystal lens and intraocular lens (vault), endothelial cell density (ECD), anterior chamber depth (ACD), surgical complication, etc.
  
  
  RESULTS
  Successful implantation was achieved in all patients. The mean follow-up time was (9.54 ± 4.12) months (SD)(range 1 to 12 months). The mean preoperative SE was -12.38 diopters (D) (range -5.0D to -23.0D). Postoperatively, UCVA was maintained or improved in all eyes. UCVA achieved 1.0 in 58 eyes (64%) and BCVA gained more than 1 line in 69 eyes (75.9%). The glare and no glare contrast sensitivity were improved at 3cd, 12cd and 18cd, with the exception of 6cd. The aberration decreased in RMS, spherical and coma. Post operative ACD (1 week after operation) diminished 8.92% as compared with the preoperative ACD. The mean vaulting was (452 ± 216.38) µm (6 months) and ranged 130 - 1080 µm at different follow-up periods. There was no statistically significant difference in vaulting between postoperative data at different periods (t = 0.200, P > 0.05). The mean postoperative ECD decreased but had no statistically difference compared with the preoperative ECD. ACD decreased 31% after surgery in 2 eyes (2.1%). Transient high IOP was observed in 13 eyes (2.1%) one week after the operation.
  
  
  CONCLUSIONS
  These results indicate that ICL implantation in the treatment of myopia is efficient, predictable, safe, and reliable.
authors.affiliation: The Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Gai-Ping
authors.initials: GP
authors.lastname: DU
authors.forename: Yi-Fei
authors.initials: YF
authors.lastname: Huang
authors.forename: Li-Qiang
authors.initials: LQ
authors.lastname: Wang
authors.forename: Da-Jiang
authors.initials: DJ
authors.lastname: Wang
authors.forename: Yu-Bo
authors.initials: YB
authors.lastname: Gong
authors.forename: Hai-Peng
authors.initials: HP
authors.lastname: Zhao
authors.forename: Mei
authors.initials: M
authors.lastname: Ge
authors.forename: Hou-Bin
authors.initials: HB
authors.lastname: Huang
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D009216:Myopia / Q000601:surgery*; D011446:Prospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult