title: Validity of the Chinese version Mood Disorder Questionnaire (MDQ) and the optimal cutoff screening bipolar disorders.
abstract: To investigate the validity of the Chinese version of Mood Disorder Questionnaire (C-MDQ) in China. Patients with bipolar disorders (BP, N=284) and patients with unipolar depressive disorder (UP, N=134) were assessed with the C-MDQ. The Eigenvalues of the first two factors were 3.15 and 2.09, respectively. The Cronbach's alpha of the C-MDQ was 0.79. The frequency of positive responses of UP patients was significantly lower than those of BP patients for 12 items except the seventh item. A C-MDQ screening score of seven or more was the best cutoff between BP and UP. The C-MDQ could distinguish between bipolar II disorder (BP-II) and UP, and the best cutoff was five. A cutoff of five had a sensitivity of 0.80 and a specificity of 0.54 between BP and UP. This study demonstrated the good validity of C-MDQ in China. The best cutoff between BP-II and UP can be regarded as the optimal cutoff between BP and UP to improve the sensitivity of screening for BP-II. Five should be the optimal cutoff between the BP and UP when only the 13 items of the questionnaire are used in China.
authors.affiliation: Mental Health Institute, the 2nd Xiangya Hospital, Central South University, Changsha, PR China. llj2920@163.com
authors.forename: Hai-Chen
authors.initials: HC
authors.lastname: Yang
authors.forename: Cheng-Mei
authors.initials: CM
authors.lastname: Yuan
authors.forename: Tie-Bang
authors.initials: TB
authors.lastname: Liu
authors.forename: Ling-Jiang
authors.initials: LJ
authors.lastname: Li
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Peng
authors.forename: Han
authors.initials: H
authors.lastname: Rong
authors.forename: Chun-Ping
authors.initials: CP
authors.lastname: Liao
authors.forename: Qi-Jie
authors.initials: QJ
authors.lastname: Shen
authors.forename: Yi-Ru
authors.initials: YR
authors.lastname: Fang
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis*; D002681:China; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012372:ROC Curve; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D011795:Surveys and Questionnaires