title: Are meaningful predictions of toxicological outcomes in clinical trials based on in vitro diagnostics of preclinical drug candidates possible?
authors.forename: Friedrich
authors.initials: F
authors.lastname: Kroll
authors.forename: Mathias
authors.initials: M
authors.lastname: Dreger
mesh_terms: D002986:Clinical Trials as Topic; D055808:Drug Discovery; D004353:Drug Evaluation, Preclinical; D064420:Drug-Related Side Effects and Adverse Reactions; D023281:Genomics; D006801:Humans; D055432:Metabolomics; D008958:Models, Molecular; D004364:Pharmaceutical Preparations / Q000378:metabolism; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D040901:Proteomics; D014116:Toxicology; D016896:Treatment Outcome
chemical_list: D004364:Pharmaceutical Preparations; D011506:Proteins