title: Recapture of GFP chromophore fluorescence in a protein host.
abstract: When encapsulated by human serum albumin (HSA), certain derivatives of the green fluorescent protein (GFP) chromophore recover their fluorescence due to inhibition of torsional motion. These derivatives show remarkable sensitivity and selectivity as well as favorable spectroscopic properties toward HSA, thus providing selective probes for this and similar proteins and demonstrating the use of GFP chromophores as topological fluorophores.
authors.forename: Anthony
authors.initials: A
authors.lastname: Baldridge
authors.forename: Suihan
authors.initials: S
authors.lastname: Feng
authors.forename: Young-Tae
authors.initials: YT
authors.lastname: Chang
authors.forename: Laren M
authors.initials: LM
authors.lastname: Tolbert
mesh_terms: D049452:Green Fluorescent Proteins / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D011487:Protein Conformation; D012709:Serum Albumin / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D012709:Serum Albumin; D049452:Green Fluorescent Proteins