title: Synthesis, spectral characterization and biological activities of Mn(II) and Co(II) complexes with benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone.
abstract: Mn(II) and Co(II) complexes of benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone have been synthesized and characterized by the investigations of electronic and EPR spectra and X-ray diffraction. Based on the spectral studies, an octahedral geometry is assigned for the Mn(II) and Co(II) complexes. X-ray powder diffraction studies reveal that Mn(II) and Co(II) complexes have triclinic crystal lattices. The unit cell parameters of the Mn(II) complex are a=11.0469 Å, b=6.2096 Å, c=7.4145 Å, α=90.646°, β=95.127°, γ=104.776°, V=489.7 Å(3) and those of Co(II) complex are a=9.3236 Å, b=10.2410 Å, c=7.8326 Å, α=90.694°, β=99.694°, γ=100.476°, V=724.2 Å(3). When the free ligand and its metal complexes are subjected to antibacterial activity, the metal complexes are proved to be more active than the ligand. However with regard to in vitro antioxidant activity, the ligand exhibits greater antioxidant activity than its metal(II) complexes.
authors.affiliation: Analytical Division, Department of Chemistry, Srivenkateswara University, Tirupati, India.
authors.forename: B
authors.initials: B
authors.lastname: Prathima
authors.forename: Y Subba
authors.initials: YS
authors.lastname: Rao
authors.forename: G N
authors.initials: GN
authors.lastname: Ramesh
authors.forename: M
authors.initials: M
authors.lastname: Jagadeesh
authors.forename: Y P
authors.initials: YP
authors.lastname: Reddy
authors.forename: P V
authors.initials: PV
authors.lastname: Chalapathi
authors.forename: A Varada
authors.initials: AV
authors.lastname: Reddy
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001547:Benzaldehydes / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry* / Q000494:pharmacology*; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D008024:Ligands; D015227:Lipid Peroxidation / Q000187:drug effects; D008345:Manganese / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010851:Picrates / Q000737:chemistry; D013499:Surface Properties / Q000187:drug effects; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D001547:Benzaldehydes; D001713:Biphenyl Compounds; D008024:Ligands; D010851:Picrates; D013882:Thiosemicarbazones; C552647:benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone; D003035:Cobalt; D008345:Manganese; C004931:1,1-diphenyl-2-picrylhydrazyl