title: Tetraalkylphosphonium-based ionic liquids for a single-step dye extraction/MALDI MS analysis platform.
abstract: Room temperature ionic liquids, or RTILs, based on tetraalkylphosphonium (PR(4)(+)) cations were used as the basis of a platform that enables separation of dyes from textiles, extraction of dyes from aqueous solution, and identification of the dyes by MALDI-MS in a single experimental step for forensic purposes. Ionic liquids were formed with PR(4)(+) cations and ferulate (FA), α-cyano-4-hydroxycinnamate (CHCA), and 2,5-dihydroxybenzoate (DHB) anions. The use of tetraalkylphosphonium-based ionic liquids in MALDI-MS allowed detection of small molecule dyes without addition of a traditional solid MALDI matrix.
authors.affiliation: Materials Physics and Applications-Material Chemistry Division (MPA-MC), Los Alamos National Laboratory, Mail Stop J514, Los Alamos, New Mexico 87545, USA.
authors.forename: Katherine S
authors.initials: KS
authors.lastname: Lovejoy
authors.forename: Geraldine M
authors.initials: GM
authors.lastname: Purdy
authors.forename: Srinivas
authors.initials: S
authors.lastname: Iyer
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Sanchez
authors.forename: Al
authors.initials: A
authors.lastname: Robertson
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Koppisch
authors.forename: Rico E
authors.initials: RE
authors.lastname: Del Sesto
mesh_terms: D004396:Coloring Agents / Q000032:analysis*; D052578:Ionic Liquids / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013237:Stereoisomerism
chemical_list: D004396:Coloring Agents; D052578:Ionic Liquids; D009943:Organophosphorus Compounds; C559940:trihexyltetradecylphosphonium chloride