title: Molecular mechanism of acquisition of the cholera toxin genes.
abstract: One of the major pathogenic determinants of Vibrio cholerae, the cholera toxin, is encoded in the genome of a filamentous phage, CTXφ. CTXφ makes use of the chromosome dimer resolution system of V. cholerae to integrate its single stranded genome into one, the other, or both V. cholerae chromosomes. Here, we review current knowledge about this smart integration process.
authors.affiliation: CNRS, Centre de Génétique Moléculaire, Gif-sur-Yvette & Université Paris-Sud, Orsay, France.
authors.forename: Bhabatosh
authors.initials: B
authors.lastname: Das
authors.forename: Julien
authors.initials: J
authors.lastname: Bischerour
authors.forename: Francois-Xavier
authors.initials: FX
authors.lastname: Barre
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D001483:Base Sequence; D002771:Cholera / Q000382:microbiology*; D002772:Cholera Toxin / Q000235:genetics*; D016680:Genome, Bacterial; D016679:Genome, Viral; D014734:Vibrio cholerae / Q000737:chemistry / Q000235:genetics* / Q000472:pathogenicity*; D016662:Virus Integration
chemical_list: D002772:Cholera Toxin