title: Adherence and biofilm formation of non-Candida albicans Candida species.
abstract: Most cases of candidosis have been attributed to Candida albicans, but recently non-C. albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases and haemolysins). Although 'new'Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of Candida glabrata, Candida parapsilosis and Candida tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.
authors.affiliation: Institute for Biotechnology and Bioengineering, Universidade do Minho, Campus de Gualtar 4710-057, Braga, Portugal.
authors.forename: Sónia
authors.initials: S
authors.lastname: Silva
authors.forename: Melyssa
authors.initials: M
authors.lastname: Negri
authors.forename: Mariana
authors.initials: M
authors.lastname: Henriques
authors.forename: Rosário
authors.initials: R
authors.lastname: Oliveira
authors.forename: David W
authors.initials: DW
authors.lastname: Williams
authors.forename: Joana
authors.initials: J
authors.lastname: Azeredo
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D002175:Candida / Q000254:growth & development / Q000472:pathogenicity / Q000502:physiology*; D002177:Candidiasis / Q000382:microbiology; D002448:Cell Adhesion; D006801:Humans