title: Monoterpenoid indole alkaloids from Gardneria ovata.
abstract: Eight new monoterpenoid indole alkaloids, gardfloramine-9-O-β-D-glucopyranoside (1), 19(E)-18-demethoxygardfloramine-N(4)-oxide (2), gardfloramine-N(4)-oxide (3), 18-demethylgardfloramine (4), 19(E)-9,18-didemethoxygardneramine (5), 19(E)-11-methoxy-9,18-didemethoxygardneramine (6), 9-demethoxy-18-demethylgardneramine (7), and minfiensine-N(4)-oxide (8), along with six known alkaloids, were isolated from Gardneria ovata. The structures of the new alkaloids were established by means of spectroscopic methods. None of the compounds were cytotoxic to five human cancer cell lines.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
authors.forename: Xiao-Ning
authors.initials: XN
authors.lastname: Li
authors.forename: Xiang-Hai
authors.initials: XH
authors.lastname: Cai
authors.forename: Tao
authors.initials: T
authors.lastname: Feng
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Liu
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Luo
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D029541:Loganiaceae / Q000737:chemistry*; D015394:Molecular Structure; D046948:Secologanin Tryptamine Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D046948:Secologanin Tryptamine Alkaloids