title: [Pulmonary valve replacement due to ectopic ossification on expanded polytetrafluoroethylene cusp after tetralogy of Fallot repair; report of a case].
abstract: Operative correction of tetralogy of Fallot has been performed for more than 50 years and well established. To date, the literature on reoperation has focused and indications and the long-term outcome have not been well defined. We herein report a case of pulmonary valve replacement due to ectopic ossification on expanded polytetrafluoroethylene (ePTFE) cusp in a female child who had undergone right ventricular outflow tract reconstruction for tetralogy of Fallot with pulmonary atresia. Because of severe right ventricular dilatation with end diastolic volume of 186 ml/m2 on cardiac catheterization, redo operation was planned for functional recovery of the right ventricle. Previous transannlar patch was removed and pulmonary valve replacement was performed using CEP 23 mm. A hard calcification was observed around the cusp of transannular patch. Pathological findings revealed ectopic ossification with osteoblast colonization around the ePTFE cusp. This is the 1st report of ectopic ossification on ePTFE.
authors.affiliation: Division of Cardiovascular Surgery, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Maekawa
authors.forename: Takahiko
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Kentaro
authors.initials: K
authors.lastname: Umezu
authors.forename: Nobuo
authors.initials: N
authors.lastname: Ohashi
authors.forename: Yorikazu
authors.initials: Y
authors.lastname: Harada
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yasukochi
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Takigiku
authors.forename: Kota
authors.initials: K
authors.lastname: Takei
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakano
authors.forename: Nao
authors.initials: N
authors.lastname: Inoue
authors.forename: Tesshu
authors.initials: T
authors.lastname: Otagiri
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Hashida
mesh_terms: D002648:Child; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D009999:Ossification, Heterotopic / Q000473:pathology*; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D011664:Pulmonary Valve / Q000601:surgery*; D011665:Pulmonary Valve Insufficiency / Q000209:etiology*; D012086:Reoperation; D013771:Tetralogy of Fallot / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene