title: Isolation and complete genomic characterization of H1N1 subtype swine influenza viruses in southern China through the 2009 pandemic.
abstract: BACKGROUND
  The swine influenza (SI) is an infectious disease of swine and human. The novel swine-origin influenza A (H1N1) that emerged from April 2009 in Mexico spread rapidly and caused a human pandemic globally. To determine whether the tremendous virus had existed in or transmitted to pigs in southern China, eight H1N1 influenza strains were identified from pigs of Guangdong province during 2008-2009.
  
  
  RESULTS
  Based on the homology and phylogenetic analyses of the nucleotide sequences of each gene segments, the isolates were confirmed to belong to the classical SI group, with HA, NP and NS most similar to 2009 human-like H1N1 influenza virus lineages. All of the eight strains were low pathogenic influenza viruses, had the same host range, and not sensitive to class of antiviral drugs.
  
  
  CONCLUSIONS
  This study provides the evidence that there is no 2009 H1N1-like virus emerged in southern China, but the importance of swine influenza virus surveillance in China should be given a high priority.
authors.affiliation: College of Animal Science, South China Agricultural University, Guangzhou 510642, PR China.
authors.forename: Yizhi
authors.initials: Y
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Ji
authors.forename: Qingmei
authors.initials: Q
authors.lastname: Xie
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Huiqin
authors.initials: H
authors.lastname: Shang
authors.forename: Cuiying
authors.initials: C
authors.lastname: Chen
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Chunyi
authors.initials: C
authors.lastname: Xue
authors.forename: Yongchang
authors.initials: Y
authors.lastname: Cao
authors.forename: Jingyun
authors.initials: J
authors.lastname: Ma
authors.forename: Yingzuo
authors.initials: Y
authors.lastname: Bi
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D023281:Genomics; D058507:Host Specificity; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification* / Q000502:physiology; D008969:Molecular Sequence Data; D009976:Orthomyxoviridae Infections / Q000662:veterinary* / Q000821:virology; D058873:Pandemics; D010802:Phylogeny; D013552:Swine; D013553:Swine Diseases / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics
chemical_list: D014764:Viral Proteins