title: Is the weighted z-test the best method for combining probabilities from independent tests?
abstract: Through simulation, Whitlock showed that when all the alternatives have the same effect size, the weighted z-test is superior to both unweighted z-test and Fisher's method when combining P-values from independent studies. In this paper, we show that under the same situation, the generalized Fisher method due to Lancaster outperforms the weighted z-test.
authors.affiliation: Biostatistics/Epidemiology/Research Design (BERD) Core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Zhongxue.Chen@uth.tmc.edu
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
mesh_terms: D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D015201:Meta-Analysis as Topic