title: Natural product biosynthesis inspired concise and stereoselective synthesis of benzopyrones and related scaffolds.
abstract: A natural product biosynthesis-inspired strategy to explore biologically relevant chemical space is presented. A phosphine-catalyzed cascade and stereoselective annulation provides a common tricyclic benzopyrone intermediate that was efficiently transformed into diverse and related naturally occurring scaffolds.
authors.affiliation: Max-Planck-Institut für molekulare Physiologie, Otto-Hahn Strasse 11, 44227-Dortmund, Germany.
authors.forename: Baburaj
authors.initials: B
authors.lastname: Baskar
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Dakas
authors.forename: Kamal
authors.initials: K
authors.lastname: Kumar
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis* / Q000378:metabolism; D001688:Biological Products / Q000096:biosynthesis / Q000138:chemical synthesis*; D002384:Catalysis; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001578:Benzopyrans; D001688:Biological Products; D010720:Phosphines