title: Assessment of the awareness and management of sleep apnea syndrome in acromegaly. The COM.E.TA (Comorbidities Evaluation and Treatment in Acromegaly) Italian Study Group.
abstract: In 2007 the Italian COM.E.T.A. (COMorbidities Evaluation and Treatment in Acromegaly) study group started to assess the application in a clinical setting of the Versailles criteria for management of acromegaly complications by a first questionnaire focusing on cardiovascular co-morbidities. A further questionnaire on sleep apnea syndrome (SAS) was delivered by the COM.E.T.A. study group to 107 endocrine centers in Italy. The results of our survey suggest that SAS is a well-known comorbidity even if its estimated prevalence is lower than in the literature. Polysomnography is the preferred tool for diagnosis. Control of SAS is considered relevant both for quality of life and co-morbidities. Continuous positive airway pressure is the cornerstone of therapy, but patients' acceptance may be critical. Control of GH/IGF-I secretion is important to improve SAS. Management of SAS requires cooperation between specialists.
authors.affiliation: Department of Internal Medicine, General Hospital, v. Monte Grappa 30, 31044 Montebelluna, Italy. ernesto.demenis@ulssasolo.ven.it
authors.forename: E
authors.initials: E
authors.lastname: De Menis
authors.forename: A
authors.initials: A
authors.lastname: Giustina
authors.forename: A
authors.initials: A
authors.lastname: Colao
authors.forename: E
authors.initials: E
authors.lastname: Degli Uberti
authors.forename: E
authors.initials: E
authors.lastname: Ghigo
authors.forename: F
authors.initials: F
authors.lastname: Minuto
authors.forename: F
authors.initials: F
authors.lastname: Bogazzi
authors.forename: R
authors.initials: R
authors.lastname: Drigo
authors.forename: A
authors.initials: A
authors.lastname: Cattaneo
authors.forename: G
authors.initials: G
authors.lastname: Aimaretti
mesh_terms: D000172:Acromegaly / Q000150:complications* / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D001364:Awareness / Q000502:physiology; D002983:Clinical Competence / Q000706:statistics & numerical data; D015897:Comorbidity; D005260:Female; D017144:Focus Groups; D006801:Humans; D007558:Italy; D008297:Male; D010820:Physicians / Q000523:psychology / Q000706:statistics & numerical data; D017286:Polysomnography / Q000706:statistics & numerical data; D015995:Prevalence; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D011795:Surveys and Questionnaires