title: Plant bioreactors for pharmaceuticals.
abstract: Plant bioreactors are attractive expression systems for economic production of pharmaceuticals. Various plant expression systems or platforms have been tested with certain degrees of success over the past years. However, further development and improvement are needed for more effective plant bioreactors. In this review we first summarize recent progress in various plant bioreactor expression systems and then focus on discussing protein compartmentation to unique organelles and various strategies for developing better plant bioreactors.
authors.affiliation: Department of Biology and Molecular Biotechnology Program, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
authors.forename: Yansong
authors.initials: Y
authors.lastname: Miao
authors.forename: Yu
authors.initials: Y
authors.lastname: Ding
authors.forename: Qiao-Yang
authors.initials: QY
authors.lastname: Sun
authors.forename: Zeng-Fu
authors.initials: ZF
authors.lastname: Xu
authors.forename: Liwen
authors.initials: L
authors.lastname: Jiang
mesh_terms: D019149:Bioreactors; D001709:Biotechnology; D018929:Cell Culture Techniques / Q000379:methods; D002736:Chloroplasts / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000302:isolation & purification*; D010938:Plant Oils / Q000378:metabolism; D018517:Plant Roots / Q000378:metabolism; D030821:Plants, Genetically Modified / Q000166:cytology / Q000235:genetics* / Q000378:metabolism*; D011480:Protease Inhibitors / Q000378:metabolism; D015202:Protein Engineering / Q000379:methods; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000235:genetics* / Q000302:isolation & purification; D012639:Seeds / Q000235:genetics / Q000378:metabolism; D014617:Vacuoles / Q000378:metabolism
chemical_list: D004364:Pharmaceutical Preparations; D010938:Plant Oils; D011480:Protease Inhibitors; D011994:Recombinant Proteins