title: High Na+ and K+ -induced fluorescence enhancement of a π-conjugated phenylaza-18-crown-6-triazol-substituted coumarin fluoroionophore.
abstract: The new π-conjugated 1,2,3-triazol-1,4-diyl fluoroionophore 1 generated via Cu(I) catalyzed [3 + 2] cycloaddition shows high fluorescence enhancement factors (FEF) in the presence of Na(+) (FEF=58) and K(+) (FEF=27) in MeCN and high selectivity towards K(+) under simulated physiological conditions (160 mM K(+) or Na(+), respectively) with a FEF of 2.5 for K(+).
authors.affiliation: Universität Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, 14467 Potsdam, Germany.
authors.forename: Sandra
authors.initials: S
authors.lastname: Ast
authors.forename: Holger
authors.initials: H
authors.lastname: Müller
authors.forename: Roman
authors.initials: R
authors.lastname: Flehr
authors.forename: Tillmann
authors.initials: T
authors.lastname: Klamroth
authors.forename: Bernd
authors.initials: B
authors.lastname: Walz
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Holdt
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D005453:Fluorescence; D015394:Molecular Structure; D011188:Potassium / Q000737:chemistry*; D012964:Sodium / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry*
chemical_list: D001372:Aza Compounds; D003374:Coumarins; D014230:Triazoles; C559586:phenylaza-18-crown-6-triazol; D003300:Copper; D012964:Sodium; C030123:coumarin; D011188:Potassium