title: Facile total synthesis of xanthorrhizol.
abstract: A facile total synthesis of the bisabolane sesquiterpene, xanthorrhizol (1), has been achieved in 6 steps, in 48% overall yield. The starting material was 3-methoxy-4-methyl-phenoacetone (7), and a Claisen-Johnson rearrangement was used as the key step to construct the skeleton of the target molecule.
authors.affiliation: College of Science, Northwest A&F University, Yangling, Shaanxi, 712100, China. duzt@nwsuafedu.cn
authors.forename: Zhenting
authors.initials: Z
authors.lastname: Du
authors.forename: Yin
authors.initials: Y
authors.lastname: Wang
authors.forename: Weili
authors.initials: W
authors.lastname: Ma
authors.forename: Dong
authors.initials: D
authors.lastname: Lv
authors.forename: Hongrui
authors.initials: H
authors.lastname: Yu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis*; D010636:Phenols / Q000138:chemical synthesis*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010636:Phenols; C120248:xanthorrhizol