title: Effects of endoscopic sinus surgery on pulmonary artery pressure in patients with extensive nasal polyposis.
abstract: OBJECTIVE
  Extensive nasal polyposis (ENP) increases upper airway obstruction. This study aimed to measure the mean pulmonary arterial pressure (mPAP) of the patients with ENP and to determine the effect of endoscopic sinus surgery on the pulmonary arterial pressure.
  
  
  METHODS
  Forty-seven patients with ENP (mean age, 37.3 [SD, 8.7] years; 29 male patients and 18 female patients) were included in the study. Thirty-two of the patients (19 male patients, 13 female patients) aged between 21 and 55 years (mean, 36.1 [SD, 8.5] years) comprised the control group. Mean pulmonary arterial pressure was measured in the preoperative period and postoperative third month.
  
  
  RESULTS
  The mean preoperative mPAP value (26.1 [SD, 5.2]) of the study group was statistically significantly higher than that of the control group (20.6 [SD, 2.8]) (P=0.000). There was a significant decrease in the mPAP after the operation (20.9 [SD, 3.8]) (P=0.000). Twenty-six of 47 patients had pulmonary arterial hypertension.
  
  
  CONCLUSIONS
  Extensive nasal polyposis significantly affected mPAP. Endoscopic surgery was efficient in the treatment of the patients with ENP.
authors.affiliation: District Education and Research Hospital, Ear Nose and Throat Department, and Cardiology Department, Ataturk University, Erzurum, Turkey. vuralf@mynet.com
authors.forename: Vural
authors.initials: V
authors.lastname: Fidan
authors.forename: Enbiya
authors.initials: E
authors.lastname: Aksakal
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004724:Endoscopy; D065627:Familial Primary Pulmonary Hypertension; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000503:physiopathology* / Q000601:surgery*; D010256:Paranasal Sinuses / Q000601:surgery*; D011651:Pulmonary Artery / Q000503:physiopathology*; D018709:Statistics, Nonparametric; D016896:Treatment Outcome