title: Toward the total synthesis of elisapterosin B: A Hg(OTf)(2)-promoted diastereoselective intramolecular Friedel-Crafts alkylation reaction.
abstract: As part of an approach to the synthesis of the antitubercular agent elisapterosin B, we prepared two different chiral, non-racemic olefinic substrates and examined their diastereoselective ring closure using mercury salts. The effort yielded potential precurors to elisapterosin B in good yield with good to excellent diastereocontrol.
authors.affiliation: Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211.
authors.forename: Weijiang
authors.initials: W
authors.lastname: Ying
authors.forename: Charles L
authors.initials: CL
authors.lastname: Barnes
authors.forename: Michael
authors.initials: M
authors.lastname: Harmata