title: Regenerative medicine for skin diseases: iPS cells to the rescue.
abstract: Induced pluripotent stem (iPS) cells reprogrammed from somatic cells have the potential to differentiate, under appropriate conditions, to any cell type. Recent studies, including two papers in this issue (Bilousova et al., 2011; Tolar et al., 2011), have demonstrated that iPS cells can differentiate into keratinocytes. Thus, iPS cells may provide a novel approach to applying regenerative medicine to cutaneous diseases such as epidermolysis bullosa.
authors.affiliation: Department of Dermatology and Cutaneous Biology, Jefferson Medical College, and Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. jouni.uitto@jefferson.edu
authors.forename: Jouni
authors.initials: J
authors.lastname: Uitto
mesh_terms: D000818:Animals; D004820:Epidermolysis Bullosa / Q000235:genetics* / Q000628:therapy*; D006801:Humans; D009030:Mosaicism; D039904:Pluripotent Stem Cells / Q000637:transplantation*; D012038:Regeneration; D033581:Stem Cell Transplantation / Q000379:methods*