title: An fMRI study of long-term everyday memory  using SenseCam.
abstract: We used a novel automatic camera, SenseCam, to investigate recognition memory for real-life events at a 5-month retention interval. Using fMRI we assessed recollection and familiarity memory using the remember/know procedure. Recollection evoked no medial temporal lobe (MTL) activation compared to familiarity and new responses. Instead, recollection activated diverse regions in neocortex including medial prefrontal cortex. We observed decreased activation in anterior hippocampus/ anterior parahippocampal gyrus (aPHG) at 5 months compared to a 36-hour retention interval. Familiarity was associated with greater activation in aPHG and posterior parahippocampal gyrus (pPHG) than recollection and new responses. Familiarity activation decreased over time in anterior hippocampus/aPHG and posterior hippocampus/pPHG. The engagement of neocortical regions such as medial prefrontal cortex at a 5-month delay, together with the reduced MTL activation at 5 months relative to at 36 hours is in line with the assumptions of Consolidation theory. SenseCam provides a valuable technique for assessing the processes that underlie remote everyday recognition memory.
authors.affiliation: Department of Psychology, University of Exeter, Exeter, UK. f.n.milton@exeter.ac.uk
authors.forename: F
authors.initials: F
authors.lastname: Milton
authors.forename: N
authors.initials: N
authors.lastname: Muhlert
authors.forename: C R
authors.initials: CR
authors.lastname: Butler
authors.forename: A
authors.initials: A
authors.lastname: Smith
authors.forename: A
authors.initials: A
authors.lastname: Benattayallah
authors.forename: A Z
authors.initials: AZ
authors.lastname: Zeman
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D003463:Cues; D004784:Environmental Monitoring / Q000295:instrumentation; D005260:Female; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D061212:Memory, Episodic; D057567:Memory, Long-Term / Q000502:physiology; D008570:Memory, Short-Term / Q000502:physiology; D011939:Mental Recall; D008838:Microcomputers; D020534:Parahippocampal Gyrus / Q000502:physiology*; D010781:Photography / Q000295:instrumentation*; D017397:Prefrontal Cortex / Q000502:physiology*; D021641:Recognition, Psychology / Q000502:physiology; D012656:Self-Help Devices; D013997:Time Factors; D055815:Young Adult