title: Imaginary magnetic tweezers for massively parallel surface adhesion spectroscopy.
abstract: A massively parallel magnetic tweezer system has been constructed that utilizes the self-repulsion of colloidal beads from a planar interface via a magnetic dipole image force. Self-repulsion enables the application of a uniform magnetic force to thousands of beads simultaneously, which permits the measurement of unbinding histograms at the lowest loading rates ever tested. The adhesion of 9.8 μm polystyrene beads to a fluorocarbon, PEG, and UV-irradiated PEG surfaces were measured between 10(-3)-10(0) pN/s force loading rates, revealing the presence of both kinetic and quasi-equilibrium unbinding regimes.
authors.affiliation: Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, United States.
authors.forename: Ye
authors.initials: Y
authors.lastname: Yang
authors.forename: Randall M
authors.initials: RM
authors.lastname: Erb
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Wiley
authors.forename: Stefan
authors.initials: S
authors.lastname: Zauscher
authors.forename: Benjamin B
authors.initials: BB
authors.lastname: Yellen
mesh_terms: D000268:Adhesiveness; D003102:Colloids / Q000737:chemistry* / Q000528:radiation effects*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008280:Magnetics / Q000295:instrumentation*; D008846:Micromanipulation / Q000295:instrumentation*; D049329:Nanostructures / Q000737:chemistry* / Q000528:radiation effects*; D052898:Optical Tweezers; D013057:Spectrum Analysis / Q000379:methods*
chemical_list: D003102:Colloids