title: [Correlation between quantitative nerve fiber layer thickness and mean defect of visual field in primary open angle glaucoma].
abstract: OBJECTIVE
  To establish whether the structural parameters provided by GDx can be used to reflect functional damage in the mean defect of visual field.
  
  
  METHODS
  97 (191 eyes) patients with primary open angle glaucoma underwent examination with GDx and Octopus 1-2-3 automatic perimeter. The relationship between the retinal nerve fiber layer parameters and mean defect of visual field was analysed by ANOVA, Pearson's correlation(r), scatter plot and linear regression.
  
  
  RESULTS
  The parameters of GDx decreased with increasing mean defect of visual field, measured both globally and regionally; r: SA = -0.58, TSNIT = -0.52, IA = -0.52, NFI = -0.48 and IES = -0.33. All parameters were negative correlation with mean defect of visual field and there was significant correlation among these parameters, except IES (P < 0.05). The superior mean defect of visual field increased with decreasing inferior RNFL (r = -0.61), inferior visual field mean defect increased with decreasing superior RNFL (r = -0.59). There were significant correlation among these parameters.
  
  
  CONCLUSIONS
  Quantitative measures of the retinal nerve fiber layer using GDx were correlated with mean defect of visual field in patients with glaucoma. GDx can be used for follow up.
authors.affiliation: Beijing Geriatric Hospital, Beijing 100095, China.
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Chen
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Rong-xiu
authors.initials: RX
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009898:Optic Disk / Q000473:pathology; D058609:Visual Field Tests; D014794:Visual Fields; D055815:Young Adult