title: The design, preparation, and use of immunopurification reagents.
abstract: Immunoaffinity chromatography using immobilized monoclonal antibodies has become one of the most powerful macromolecular separation methods available. In many cases, simple one-step immunoaffinity separations will produce a several thousand-fold purification with yields of better than 80%. Monoclonal antibodies are now available with specificities for many different antigens, and the technology for producing new monoclonal antibodies has become widespread througout the world since its invention (1; see vol. 1 of this series). It has been estimated that a new monoclonal antibody is produced every 40 min worldwide.
authors.affiliation: Downstream Processing Department, Celltech Ltd., Slough, Berkshire, UK.
authors.forename: A
authors.initials: A
authors.lastname: Kenney
authors.forename: L
authors.initials: L
authors.lastname: Goulding
authors.forename: C
authors.initials: C
authors.lastname: Hill