title: [Morphological and immunohistochemical studies of palatine tonsillar hypertrophy in children].
abstract: The paper presents the results of immunohistochemical and morphometric studies conducted to examine an association of the site, the expression of virus antigens, and the nature of morphological changes in the hypertrophic palatine tonsils in children. The distribution of CD3+ and CD20+ cells was explored in tonsillar tissue. The greatest changes were shown in the epithelium, the antigens of herpex simplex virus being more frequently detected than those of human papillomavirus. The presented data may be suggestive of the important role of viruses in the development of palatine tonsillar pathology, different protective reactions of various palatine tonsillar structures, which should be borne in mind during etiopathogenetic therapy.
authors.forename: T A
authors.initials: TA
authors.lastname: Iudina
authors.forename: R A
authors.initials: RA
authors.lastname: Nasyrova
mesh_terms: D052685:Alphapapillomavirus / Q000276:immunology / Q000378:metabolism; D018951:Antigens, CD20 / Q000276:immunology / Q000378:metabolism; D000956:Antigens, Viral / Q000096:biosynthesis / Q000276:immunology; D017252:CD3 Complex / Q000276:immunology / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D005260:Female; D006561:Herpes Simplex / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D014066:Palatine Tonsil / Q000276:immunology / Q000378:metabolism / Q000473:pathology / Q000821:virology; D030361:Papillomavirus Infections / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D010608:Pharyngeal Diseases / Q000276:immunology / Q000378:metabolism / Q000473:pathology / Q000821:virology; D018139:Simplexvirus / Q000276:immunology / Q000378:metabolism
chemical_list: D018951:Antigens, CD20; D000956:Antigens, Viral; D017252:CD3 Complex