title: Cerebral oximetry for pediatric anesthesia: why do intelligent clinicians disagree?
abstract: Reflectance near-infrared spectroscopy has been used to measure cortical tissue oximetry for more than 30 years. In that time, many centers have adopted the routine use of the cerebral oximeter for children having repair of congenital heart lesions, while some prominent academic centers have resisted routine use of these monitors citing lack of definitive evidence for outcome benefit. In this review, we provide an overview of the method used to measure cerebral oximetry, as well as validation and clinical outcome data that have accrued from the use of cerebral oximeters. We discuss the peculiarities of evidentiary review for monitoring devices, and the confounding errors that occur when a monitor is evaluated as a therapeutic intervention. We outline the physiologic basis of cerebral desaturation and the shifts in practice that have occurred with implementation of NIRS monitoring.
authors.affiliation: Department of Pediatric Anesthesia, Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: Nicholette
authors.initials: N
authors.lastname: Kasman
authors.forename: Ken
authors.initials: K
authors.lastname: Brady
mesh_terms: D000758:Anesthesia; D001923:Brain Chemistry / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010092:Oximetry / Q000379:methods*; D015203:Reproducibility of Results; D019265:Spectroscopy, Near-Infrared; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins