title: Type of milk feeding affects hematological parameters and serum lipid profile in Japanese infants.
abstract: BACKGROUND
  Type and volume of infant feeding determines infant growth, hematological parameters, and serum lipids.
  
  
  METHODS
  Study subjects consisted of 103 infants who were born vaginally at term, with birthweight >2200 g. Milk feeding amount, type, and anthropometry were measured at 1 and 6 months. Hematological tests and serum lipid profile were assessed at 1 and 6 months. Thirty-four infants were breast-fed and 36 were formula-fed at 6 months.
  
  
  RESULTS
  Breast-fed infants demonstrated similar growth patterns compared with partially breast-fed or formula-fed infants, despite the lower milk intake. Infants with higher breast milk intake at 6 months, however, tended to have lower hemoglobin levels. In contrast, higher formula intake at 6 months was related to lower serum total cholesterol.
  
  
  CONCLUSIONS
  Japanese breast-fed infants were more likely to be anemic at 6 months, while formula-fed infants were likely to have low serum lipid levels. Iron-fortified infant foods may be useful to prevent anemia in breast-fed infants. Fat quality of infant formulas should be improved to enhance lipid status of formula-fed infants.
authors.affiliation: Department of Health Promotion, National Institute of Public Health, Wako, Japan.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Isomura
authors.forename: Hidemi
authors.initials: H
authors.lastname: Takimoto
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Miura
authors.forename: Shigetaka
authors.initials: S
authors.lastname: Kitazawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Takeuchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Itabashi
authors.forename: Noriko
authors.initials: N
authors.lastname: Kato
mesh_terms: D000740:Anemia / Q000097:blood / Q000453:epidemiology* / Q000517:prevention & control; D000818:Animals; D001835:Body Weight; D001942:Breast Feeding; D002657:Child Development / Q000502:physiology*; D002149:Energy Intake / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007225:Infant Food; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008055:Lipids / Q000097:blood*; D008297:Male; D008892:Milk; D015995:Prevalence; D012189:Retrospective Studies
chemical_list: D008055:Lipids