title: [In vitro platelet production].
abstract: This review aims at presenting a state of the art on platelet functions, not only in well-characterized hemostasis and thrombosis, but also in various domains such as inflammation, immunity, angiogenesis, source of growth factors, metastasis and vascular remodelling. This multivalent phenotype of platelets suggests new potential applications of platelets. The second objective is to present new advances in platelet formation from megakaryocytes and direct platelet release, as initially shown by our group and more recently by others.
authors.affiliation: Unité 765, Inserm, 4, avenue de l'Observatoire, 75270 Paris cedex 06, France.
authors.forename: C
authors.initials: C
authors.lastname: Dunois-Lardé
authors.forename: D
authors.initials: D
authors.lastname: Baruch
mesh_terms: D000818:Animals; D001791:Blood Platelet Disorders / Q000097:blood / Q000235:genetics / Q000473:pathology; D001792:Blood Platelets / Q000166:cytology* / Q000276:immunology / Q000502:physiology; D018929:Cell Culture Techniques / Q000379:methods*; D055252:Cell-Derived Microparticles; D002478:Cells, Cultured / Q000166:cytology; D006801:Humans; D007157:Immunologic Surveillance; D018836:Inflammation Mediators / Q000097:blood; D008533:Megakaryocytes / Q000166:cytology; D009369:Neoplasms / Q000097:blood / Q000098:blood supply; D009389:Neovascularization, Pathologic; D015539:Platelet Activation; D017713:Platelet Transfusion; D034061:Thrombopoiesis
chemical_list: D018836:Inflammation Mediators