title: [Lung morphological changes in premature neonates with hyaline membrane disease due to the use of exogenous surfactants during mechanical ventilation].
abstract: A complex of studies was used in 4 groups of premature babies to study lung tissue morphological changes in hyaline membrane disease, by applying exogenous surfactants during mechanical ventilation. Background diseases, pre- and intranatal risk factors, the babies' longevity, and the specific features of lung tissue and forming hyaline membranes were ascertained. Exogenous surfactants were found to have a blocking effect on the formation of hyaline membranes under mechanical ventilation.
authors.forename: A M
authors.initials: AM
authors.lastname: Golubev
authors.forename: S A
authors.initials: SA
authors.lastname: Perepelitsa
authors.forename: E F
authors.initials: EF
authors.lastname: Smerdova
authors.forename: V V
authors.initials: VV
authors.lastname: Moroz
mesh_terms: D005260:Female; D006801:Humans; D006819:Hyaline Membrane Disease / Q000473:pathology* / Q000628:therapy; D007231:Infant, Newborn; D007234:Infant, Premature; D008168:Lung / Q000378:metabolism / Q000473:pathology*; D008297:Male; D011663:Pulmonary Surfactants / Q000494:pharmacology*; D012121:Respiration, Artificial
chemical_list: D011663:Pulmonary Surfactants