title: Fracture risk assessed by Fracture Risk Assessment Tool (FRAX) compared with fracture risk derived from population fracture rates.
abstract: OBJECTIVE
  To evaluate the performance of the Swedish version of Fracture Risk Assessment Tool (FRAX)) without bone mass density (BMD) in a Danish population to examine the possibility of applying this version to Danish women.
  
  
  METHODS
  From the Danish National Register of social security numbers, we randomly selected 5000 women living in the region of Southern Denmark aged 40-90 years to receive a mailed questionnaire concerning risk factors for osteoporosis based on FRAX. The predicted 10-year probability of hip fractures was calculated for each woman returning a complete questionnaire using the Swedish version of FRAX. The observed 10-year hip fracture risk was also calculated for each woman using age-specific hip fracture rates from the National Hospital Discharge Register and National survival tables.
  
  
  RESULTS
  A total of 4194 (84%) women responded to the questionnaire and 3636 (73%) gave complete information and were included in the analysis. Using FRAX, the predicted 10-year fracture risk was 7.6%, ranging from 0.3 to 25.0% at the age of 41-50 and 81-90, respectively, while the corresponding observed fracture risk was 7.6%, ranging from 0.4 to 24.0%, respectively and not significantly different from the predicted risk (p = 0.92).
  
  
  CONCLUSIONS
  The Swedish version of FRAX without BMD is applicable to Danish women.
authors.affiliation: Institute of Clinical Research, University of Southern Denmark, Denmark. Krubin@health.sdu.dk
authors.forename: Katrine Hass
authors.initials: KH
authors.lastname: Rubin
authors.forename: Bo
authors.initials: B
authors.lastname: Abrahamsen
authors.forename: Anne Pernille
authors.initials: AP
authors.lastname: Hermann
authors.forename: Mickael
authors.initials: M
authors.lastname: Bech
authors.forename: Jeppe
authors.initials: J
authors.lastname: Gram
authors.forename: Kim
authors.initials: K
authors.lastname: Brixen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006620:Hip Fractures / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D058866:Osteoporotic Fractures / Q000453:epidemiology / Q000209:etiology*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D011795:Surveys and Questionnaires