title: [Evaluation of cerebrovascular reserve by xenon computed tomography in patients with ischemic stroke].
abstract: OBJECTIVE
  To evaluate the cerebrovascular reserve (CVR) in patients of ischemic stroke with cerebrovascular stenosis by Xenon-enhanced CT.
  
  
  METHODS
  Twenty subjects of ischemic stroke with cerebrovascular stenosis were recruited. All subjects were examined by Xenon-enhanced CT before and after acetazolamide (ACZ) challenge test to quantitatively measure the regional cerebral blood flow (rCBF) and CVR.
  
  
  RESULTS
  We compared the rCBF in the corresponding region supplied with stenosed artery (divided manually) with that in the region of normal side. There was no significant difference in resting rCBF but in CVR [ipsilateral side vs. normal side (5.9 ± 24.3)% vs (25.9 ± 32.6)%, P < 0.05].
  
  
  CONCLUSIONS
  Impaired CVR is an important character of the patients with cerebrovascular stenosis suffered from ischemic stroke.
authors.affiliation: Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Wen-jie
authors.initials: WJ
authors.lastname: Cao
authors.forename: Qiang
authors.initials: Q
authors.lastname: Dong
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014978:Xenon
chemical_list: D014978:Xenon