title: Successful memory response following a booster dose with a virosome-formulated hepatitis a vaccine delayed up to 11 years.
abstract: Boosting adult travelers with the virosome-formulated, aluminum-free hepatitis A vaccine Epaxal up to 128 months after a single primary dose confers full protection against hepatitis A, even in travelers aged 50 years and above. Delaying the booster dose did not influence the immune memory response to Epaxal.
authors.affiliation: Medical Department Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel, Switzerland. christoph.hatz@unibas.ch
authors.forename: Christoph
authors.initials: C
authors.lastname: Hatz
authors.forename: Robert
authors.initials: R
authors.lastname: van der Ploeg
authors.forename: Bernhard R
authors.initials: BR
authors.lastname: Beck
authors.forename: Gert
authors.initials: G
authors.lastname: Frösner
authors.forename: Marjory
authors.initials: M
authors.lastname: Hunt
authors.forename: Christian
authors.initials: C
authors.lastname: Herzog
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006506:Hepatitis A / Q000276:immunology / Q000517:prevention & control*; D022362:Hepatitis A Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D006801:Humans; D007117:Immunization, Secondary / Q000379:methods*; D007156:Immunologic Memory; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D022721:Vaccines, Virosome / Q000008:administration & dosage / Q000276:immunology
chemical_list: D022362:Hepatitis A Vaccines; D022721:Vaccines, Virosome; C530970:epaxal berna