title: Self-reported symptoms of psychological well-being in young adults who underwent resective epilepsy surgery in childhood.
abstract: OBJECTIVE
  This study investigated the relationship of childhood resective surgery for lesional epilepsy and recent seizure history on self-reported symptoms of mood and psychological distress in young adults (aged 18-30).
  
  
  METHODS
  Ninety-eight individuals with epilepsy of childhood onset were divided into three groups: a seizure-free surgical group (n = 39), a surgical group still experiencing seizures (n = 31), and a nonsurgical epilepsy comparison group (n = 28). Participants completed two standardized questionnaires about current mood state and psychological and psychiatric symptoms: the Profile of Mood States (POMS) and the Symptom Checklist-90 Revised (SCL-90R).
  
  
  RESULTS
  Forty-eight percent of all participants reported a history of psychological problems. The percentage of the seizure-free surgical group who met the SCL-90R criteria for current clinically significant distress was statistically less than in the other groups. Those who were seizure free also reported significantly fewer total symptoms on the SCL-90R. The current number of antiepileptic medications was related to scores on a number of the scales.
  
  
  CONCLUSIONS
  These results provide modest support for the contention that seizure freedom after pediatric epilepsy surgery is associated with reduced risk for psychological distress during early adulthood.
authors.affiliation: University of Toronto Mississauga, Mississauga, Ontario, Canada. marylou.smith@utoronto.ca
authors.forename: Mary Lou
authors.initials: ML
authors.lastname: Smith
authors.forename: Kristin
authors.initials: K
authors.lastname: Kelly
authors.forename: Darren S
authors.initials: DS
authors.lastname: Kadis
authors.forename: Irene M
authors.initials: IM
authors.lastname: Elliott
authors.forename: Janet
authors.initials: J
authors.lastname: Olds
authors.forename: Sharon
authors.initials: S
authors.lastname: Whiting
authors.forename: Thomas
authors.initials: T
authors.lastname: Snyder
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000927:Anticonvulsants / Q000627:therapeutic use; D001294:Attitude to Health; D002648:Child; D018572:Disease-Free Survival; D004827:Epilepsy / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000453:epidemiology*; D019964:Mood Disorders / Q000175:diagnosis / Q000453:epidemiology; D019635:Neurosurgical Procedures / Q000379:methods / Q000706:statistics & numerical data; D010555:Personality Inventory; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology; D057566:Self Report; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000927:Anticonvulsants