title: [Leiomyosarcoma of the submandibular gland].
abstract: BACKGROUND
  A leiomyosarcoma is a malignant tumor of the smooth muscle. Its malignancy is difficult to assess. Submandibular gland involvement is extremely rare.
  
  
  METHODS
  A 62-year-old patient was admitted with a primary leiomyosarcoma of the submandibular gland. He was treated by surgery and radiotherapy. The patient died 11 months later from pulmonary metastases.
  
  
  CONCLUSIONS
  LMS of the submandibular gland is extremely rare. Its diagnosis is very difficult because of the non-specific clinical and radiological signs. The histological diagnosis often relies on immunohistochemistry. Treatment is based on surgery associated to radiotherapy. The prognosis remains poor because of frequent recurrence and metastases.
authors.affiliation: Service d'oto-rhino-laryngologie et chirurgie cervicofaciale, hôpital militaire d'instruction Mohammed V, Hay Riyad, Rabat, Morocco. drnadourorl@hotmail.fr
authors.forename: K
authors.initials: K
authors.lastname: Nadour
authors.forename: B
authors.initials: B
authors.lastname: Bouaity
authors.forename: N
authors.initials: N
authors.lastname: Touihem
authors.forename: N
authors.initials: N
authors.lastname: Errami
authors.forename: B
authors.initials: B
authors.lastname: Hemmaoui
authors.forename: F
authors.initials: F
authors.lastname: Benariba
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D018714:Radiotherapy, Adjuvant; D013365:Submandibular Gland Neoplasms / Q000175:diagnosis* / Q000601:surgery