title: Parkinsonism caused by adverse drug reactions: a case series.
abstract: BACKGROUND
  Parkinsonism puts a high direct cost burden on both patient and caregiver. Several reports of drug-induced parkinsonism have been published, but to the best of our knowledge, there has not been any report of quinine or halothane inducing parkinsonism.
  
  
  METHODS
  We describe two cases of parkinsonism possibly caused by adverse drug reaction to quinine in a 29-year-old black Nigerian woman and to halothane in a 36-year-old black Hausa (Nigerian) man who received it as general anaesthesia for appendicectomy in our teaching hospital.
  
  
  CONCLUSIONS
  These are two unusual cases of parkinsonism caused by adverse drug reactions to high-dose quinine and to halothane as general anaesthesia. We consider that these two cases are important in bringing this potential side-effect to the attention of both pharmacologists and primary care physicians as these are two of the most commonly used medications in our clinics. We conclude that parkinsonism should be included among the adverse drug reactions to high-dose quinine and halothane general anaesthetic.
authors.affiliation: Department of Medicine, Jos University Teaching Hospital, PMB 2076, Jos, Nigeria. docsouls@yahoo.com.
authors.forename: Solomon O
authors.initials: SO
authors.lastname: Ugoya
authors.forename: Emmanuel I
authors.initials: EI
authors.lastname: Agaba
authors.forename: Comfort A
authors.initials: CA
authors.lastname: Daniyam