title: Gastrointestinal relapse of multiple myeloma and sustained response to lenalidomide: a case report.
abstract: BACKGROUND
  Gastrointestinal relapse in patients with multiple myeloma is very rare and, when reported, always associated with a poor prognosis.
  
  
  METHODS
  We describe the case of a 71-year-old Caucasian man who presented with life-threatening hematemesis and melena due to a digestive relapse of his multiple myeloma. Despite the active hemorrhage, we initiated a third-line treatment with lenalidomide. The response was spectacular and long-lasting.
  
  
  CONCLUSIONS
  Clinicians must consider digestive tract involvement in myeloma patients presenting with a gastrointestinal hemorrhage. Furthermore, myeloma patients do benefit from novel oral drugs, even when they are critically ill.
authors.affiliation: Centre for Oncology, Geneva University Hospital, 4 rue Gabrielle Perret-Gentil, 1211 Geneva 14, Switzerland. Patrick.Benusiglio@hcuge.ch.
authors.forename: Patrick R
authors.initials: PR
authors.lastname: Benusiglio
authors.forename: Thomas A
authors.initials: TA
authors.lastname: McKee
authors.forename: Xavier
authors.initials: X
authors.lastname: Montet
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Dumonceau
authors.forename: Laurence
authors.initials: L
authors.lastname: Favet
authors.forename: Anne-Claude
authors.initials: AC
authors.lastname: George
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Dietrich