title: [Acquired ichthyosis and livedoid palmoplantar keratoderma: two unusual skin manifestations of systemic lupus erythematosus].
abstract: Acquired ichthyosis and livedoid palmoplantar keratoderma have rarely been described in systemic lupus erythematosus (SLE). In the first case, a 51-year-old man presented with generalized acquired ichthyosis associated with renal glomurelosclerosis and neurolupus. rituximab allowed total resolution of the acquired ichthyosis. A livedoid palmoplantar keratoderma was observed in a 45-year-old woman as the initial clinical manifestation of a systemic lupus erythematosus associated with Raynaud's phenomenon, photosensitivity and inflammatory polyarthralgia. Although the pathophysiology is not well-defined, these unusual cutaneous manifestations should be considered by physicians when diagnosis of SLE is suspected.
authors.affiliation: Service de dermatologie, hôpital Saint-Jacques, 2 place Saint-Jacques, Besançon cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Biver-Dalle
authors.forename: H
authors.initials: H
authors.lastname: Gil
authors.forename: N
authors.initials: N
authors.lastname: Méaux-Ruault
authors.forename: I
authors.initials: I
authors.lastname: Mermet-Ginet
authors.forename: F
authors.initials: F
authors.lastname: Aubin
authors.forename: P
authors.initials: P
authors.lastname: Humbert
authors.forename: N
authors.initials: N
authors.lastname: Magy-Bertrand
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis* / Q000209:etiology; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis* / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000175:diagnosis