title: Combined carcinoid tumor and squamous cell carcinoma of lung: expanding the spectrum of combined tumors of lung.
abstract: Combined lung cancers containing both small cell and non-small cell carcinoma elements are uncommon but well recognized. Lung tumors with neuroendocrine differentiation form a group of histologically distinct tumors with differing clinical behavior ranging from low-grade tumors with good prognosis (typical carcinoid) to intermediate-grade tumors (atypical carcinoid) to high-grade tumors with poor prognosis (small cell carcinoma and large cell neuroendocrine tumors). The authors report clinical findings and pathologic findings in a case of combined carcinoid tumor and squamous cell carcinoma of lung. To the best of the authors' knowledge, this is the first report of such a case in the peer reviewed literature, thus broadening the spectrum of combined lung tumors.
authors.affiliation: UMASS Memorial Medical Center, University of Massachusetts, Worcester, MA 01605, USA. christopher.owens@umassmemorial.org
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Owens
authors.forename: Armando E
authors.initials: AE
authors.lastname: Fraire
mesh_terms: D002276:Carcinoid Tumor; D018278:Carcinoma, Neuroendocrine; D018288:Carcinoma, Small Cell; D002294:Carcinoma, Squamous Cell; D006801:Humans; D008175:Lung Neoplasms; D018358:Neuroendocrine Tumors