title: Allobetulin and its derivatives: synthesis and biological activity.
abstract: This review covers the chemistry of allobetulin analogs, including their formation by rearrangement from betulin derivatives, their further derivatisation, their fusion with heterocyclic rings, and any further rearrangements of allobetulin compounds including ring opening, ring contraction and ring expansion reactions. In the last part, the most important biological activities of allobetulin derivatives are listed. One hundred and fifteen references are cited and the relevant literature is covered, starting in 1922 up to the end of 2010.
authors.affiliation: Molecular Design and Synthesis, Department of Chemistry, University of Leuven, Celestijnenlaan 200F, 3-3001 Leuven, Belgium. wim.dehaen@chem.kuleuven.be
authors.forename: Wim
authors.initials: W
authors.lastname: Dehaen
authors.forename: Anastassiya A
authors.initials: AA
authors.lastname: Mashentseva
authors.forename: Talgat S
authors.initials: TS
authors.lastname: Seitembetov
mesh_terms: D000818:Animals; D051379:Mice; D015394:Molecular Structure; D014315:Triterpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000094062:Betulinic Acid
chemical_list: D014315:Triterpenes; C002503:betulin; D000094062:Betulinic Acid