title: A diabetic foot ulcer pilot study: does silicone gel sheeting reduce the incidence of reulceration?
abstract: BACKGROUND
  Silicone gel sheeting is an effective therapeutic intervention in the management of scar tissue. This pilot study was designed to examine the effect of silicone gel sheeting in preventing reulceration at former wound sites in diabetic patients.
  
  
  METHODS
  Thirty patients with diabetes and a healed plantar neuropathic foot ulcer were enrolled and investigated in this randomized controlled trial. Participants with a newly healed ulcer were assigned to use either silicone gel sheeting or emollient cream daily for 3 months.
  
  
  RESULTS
  Compared with emollient cream use, the use of silicone gel sheeting did not diminish and may have potentially increased the risk of reulceration.
  
  
  CONCLUSIONS
  Silicone gel sheeting does not seem to reduce the risk of reulceration in diabetic patients. The results of this trial should be viewed with caution given the small sample size.
authors.affiliation: Podiatry Department, Royal Perth Hospital, Perth, Australia. cara.westphal@health.wa.gov.au
authors.forename: Cara
authors.initials: C
authors.lastname: Westphal
authors.forename: Ingrid M
authors.initials: IM
authors.lastname: Neame
authors.forename: Jessica C
authors.initials: JC
authors.lastname: Harrison
authors.forename: Virginia M
authors.initials: VM
authors.lastname: Bower
authors.forename: Joel M
authors.initials: JM
authors.lastname: Gurr
mesh_terms: D000287:Administration, Topical; D000328:Adult; D047070:Bandages, Hydrocolloid; D017719:Diabetic Foot / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012189:Retrospective Studies; D055502:Secondary Prevention; D020034:Silicone Gels / Q000008:administration & dosage*; D016896:Treatment Outcome; D014904:Western Australia / Q000453:epidemiology; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D020034:Silicone Gels