title: Barr body in fine needle aspiration cytology of ovarian malignancies.
abstract: The Barr body is the inactive X chromosome in a female somatic cell. It is readily identified as plano-convex structure of 2-3 micron in diameter on the periphery of the nuclear membrane. The aim of this study is to evaluate the significance of Barr body count in malignant ovarian tumors on fine needle aspiration cytology (FNAC) smears. In this retrospective study, Barr body was counted in FNAC smears of 20 successive malignant ovarian lesions and expressed as percentage. Mean (±SD) Barr body score was 2.4 ± 2.58. Minimum Barr body count was 1 and maximum was 9. The gross reduction of Barr body in ovarian neoplasms is an interesting cytomorphologic finding.
authors.affiliation: Department of Cytology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Pallavi
authors.initials: P
authors.lastname: Agrawal
authors.forename: Pranab
authors.initials: P
authors.lastname: Dey
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002675:Child, Preschool; D041321:Chromosomes, Human, X; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009685:Nuclear Envelope / Q000473:pathology; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D010053:Ovary / Q000473:pathology*; D012189:Retrospective Studies; D012728:Sex Chromatin / Q000473:pathology*; D014626:Vaginal Smears / Q000379:methods; D055815:Young Adult