title: [Research progress about Wapl gene].
abstract: In Drosophila melanogasler,the wings apart-like (wapl) gene encodes a protein that regulates heterochromatin structure. Human wapl gene is human homolognue of wapl,they have same function. HWAPL is a cohesion-binding protein that affect chromosomal segregation. It has a character of oncoproteins and linked to cervical carcinogenesis and tumor progression.
authors.affiliation: Jiaxing University Collieg of Medical, Zhejiang Jiaxing 314001, China.
authors.forename: Li-Xian
authors.initials: LX
authors.lastname: Cao
authors.forename: Zhong-Fei
authors.initials: ZF
authors.lastname: Shen
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Pan
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000235:genetics* / Q000502:physiology*; D018797:Cell Cycle Proteins / Q000378:metabolism*; D002842:Chromatids / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics / Q000502:physiology; D005260:Female; D006801:Humans; D009687:Nuclear Proteins / Q000235:genetics* / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000235:genetics* / Q000502:physiology*; D002583:Uterine Cervical Neoplasms / Q000235:genetics; D000097722:Cohesins
chemical_list: D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D002868:Chromosomal Proteins, Non-Histone; D029721:Drosophila Proteins; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D000097722:Cohesins; C488092:WAPL protein, human; C554564:Wapl protein, Drosophila