title: Rapid one-pot, four-step synthesis of highly fluorescent 1,3,4,5-tetrasubstituted pyrazoles.
abstract: 1,3,4,5-Tetrasubstituted pyrazoles can be rapidly and efficiently synthesized in a one-pot, four-step sequence consisting of Sonogashira coupling, addition-cyclocondensation, bromination, and Suzuki coupling. The second and the last step are microwave-assisted, and according to sequential catalysis, no addition of further Pd catalyst is needed for the terminal step. The title compounds show intense blue fluorescence and high quantum yields.
authors.affiliation: Institut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf , Universitätsstrasse 1, D-40225 Düsseldorf, Germany.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Willy
authors.forename: Thomas J J
authors.initials: TJ
authors.lastname: Müller