title: Pseudoepitheliomatous hyperplasia: a review.
abstract: Pseudoepitheliomatous hyperplasia (PEH) is a benign condition, characterized by hyperplasia of the epidermis and adnexal epithelium, closely simulating squamous cell carcinoma. PEH may be present in a number of conditions characterized by prolonged inflammation and/or chronic infection, as well as in association with many cutaneous neoplasms. Herein, we review different inflammatory, infectious, and neoplastic skin diseases, in which florid epidermal hyperplasia is a prominent histopathologic feature, and introduce a systematic approach in the interpretation of PEH.
authors.affiliation: Dermatology and Pathology, Yale Dermatopathology Laboratory, Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: Maya
authors.initials: M
authors.lastname: Zayour
authors.forename: Rossitza
authors.initials: R
authors.lastname: Lazova
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003937:Diagnosis, Differential; D004848:Epithelium / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D012878:Skin Neoplasms / Q000473:pathology