title: [Characterization of hyper-responder patients to cardiac resynchronization therapy].
abstract: OBJECTIVE
  To compare clinical and echocardiographic characteristics of the hyper-responders to cardiac resynchronization therapy (CRT) with the rest of patients.
  
  
  METHODS
  We included 80 consecutive patients treated with CRT. The follow up was 19 (14) months. Patients were considered hyper-responder if they had an ejection fraction of left ventricle (LVEF) ≥ 50% after follow up.
  
  
  RESULTS
  Twelve (15%) patients were considered hyper-responders. Their baseline clinical characteristics were similar to the rest except that there were fewer males in the group of hyper-responders. In these patients, basal left ventricle diastolic diameter was 64 (7) mm and the systolic was 55 (6) mm versus 75 (8) mm and 66 (9) mm respectively, p < 0.05. The basal area of mitral regurgitation in the hyper-responders was 3.1 (1.8) cm(2) versus 6.4 (5.5) cm(2), p < 0.05.
  
  
  CONCLUSIONS
  Hyper-responder patients are often women with less dilated left ventricle and reduced severity of mitral regurgitation assessed by echocardiography.
authors.affiliation: Unidad de Cardiología, Hospital Infanta Cristina, Parla, Madrid, España. anarodriguezal@yahoo.es
authors.forename: Ana
authors.initials: A
authors.lastname: Rodríguez-Almodóvar
authors.forename: Dolores
authors.initials: D
authors.lastname: Mesa Rubio
authors.forename: Carmen
authors.initials: C
authors.lastname: Durán Torralba
authors.forename: Martin
authors.initials: M
authors.lastname: Ruiz Ortiz
authors.forename: Mónica
authors.initials: M
authors.lastname: Delgado Ortega
authors.forename: Amador
authors.initials: A
authors.lastname: López Granados
mesh_terms: D000368:Aged; D058406:Cardiac Resynchronization Therapy; D015897:Comorbidity; D017147:Defibrillators, Implantable; D003971:Diastole; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000628:therapy; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging; D009929:Organ Size; D011446:Prospective Studies; D012737:Sex Factors; D013318:Stroke Volume; D016896:Treatment Outcome; D014463:Ultrasonography; D020257:Ventricular Remodeling