title: Chemical constituents and antioxidant activity of Ficus callosa.
abstract: One new megastigmane glycoside, ficalloside (1), and eleven known compounds, were isolated from methanol extract of Ficus callosa leaves by repeated column chromatography. Their structures were established on the basis of spectral and chemical evidence. The antioxidant activities of these compounds were measured using the oxygen radical absorbance capacity (ORAC) assay. Compound 8 exhibited potent antioxidant activity of 10.6 microM trolox equivalents at the concentration of 2 microM. At this concentration, compounds 4-7 and 9-12 showed significant antioxidant activity with ranging of 2.1-6.1 microM trolox equivalents.
authors.affiliation: Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam. phankiem@vast.ac.vn
authors.forename: Phan
authors.initials: P
authors.lastname: Van Kiem
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Cuong
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Nhiem
authors.forename: Dan Thi Thuy
authors.initials: DT
authors.lastname: Hang
authors.forename: Nguyen Hoai
authors.initials: NH
authors.lastname: Nam
authors.forename: Ninh Khac
authors.initials: NK
authors.lastname: Ban
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
authors.forename: Zhou
authors.initials: Z
authors.lastname: Bing
authors.forename: Hae Dong
authors.initials: HD
authors.lastname: Jang
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D030681:Ficus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D010936:Plant Extracts