title: Present-day treatment of tuberculosis and latent tuberculosis infection.
abstract: The major objectives of tuberculosis (TB) control are to reduce morbidity and mortality via an early and appropriate treatment of the disease, to prevent carriers of the Mycobacterium tuberculosis bacillus from transmitting it to others, and to prevent latent tuberculosis infection (LTB) sufferers from progressing to the disease. To achieve these objectives, it is imperative to start an appropriate, effective antituberculosis treatment as early as possible, as well as identify contacts of the infected TB patient and others at risk of LTB progressing to TB, in order to establish an appropriate treatment for them. Here we review the bases for treating TB and LTB infections, including those produced by strains resistant to anti-TB drugs.
authors.affiliation: Hospital de Poniente, El Ejido, Almería, Spain.
authors.forename: Inés
authors.initials: I
authors.lastname: Pérez-Camacho
authors.forename: Antonio
authors.initials: A
authors.lastname: Rivero-Juárez
authors.forename: José María
authors.initials: JM
authors.lastname: Kindelán
authors.forename: Antonio
authors.initials: A
authors.lastname: Rivero
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use*; D002353:Carrier State / Q000188:drug therapy; D016358:Contact Tracing; D018450:Disease Progression; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D042241:Early Diagnosis; D006801:Humans; D055985:Latent Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D017410:Practice Guidelines as Topic; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents