title: Protocol: developing a conceptual framework of patient mediated knowledge translation, systematic review using a realist approach.
abstract: BACKGROUND
  Patient involvement in healthcare represents the means by which to achieve a healthcare system that is responsive to patient needs and values. Characterization and evaluation of strategies for involving patients in their healthcare may benefit from a knowledge translation (KT) approach. The purpose of this knowledge synthesis is to develop a conceptual framework for patient-mediated KT interventions.
  
  
  METHODS
  A preliminary conceptual framework for patient-mediated KT interventions was compiled to describe intended purpose, recipients, delivery context, intervention, and outcomes. A realist review will be conducted in consultation with stakeholders from the arthritis and cancer fields to explore how these interventions work, for whom, and in what contexts. To identify patient-mediated KT interventions in these fields, we will search MEDLINE, the Cochrane Library, and EMBASE from 1995 to 2010; scan references of all eligible studies; and examine five years of tables of contents for journals likely to publish quantitative or qualitative studies that focus on developing, implementing, or evaluating patient-mediated KT interventions. Screening and data collection will be performed independently by two individuals.
  
  
  CONCLUSIONS
  The conceptual framework of patient-mediated KT options and outcomes could be used by healthcare providers, managers, educationalists, patient advocates, and policy makers to guide program planning, service delivery, and quality improvement and by us and other researchers to evaluate existing interventions or develop new interventions. By raising awareness of options for involving patients in improving their own care, outcomes based on using a KT approach may lead to greater patient-centred care delivery and improved healthcare outcomes.
authors.affiliation: Departments of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada. anna.gagliardi@uhnresearch.ca
authors.forename: Anna R
authors.initials: AR
authors.lastname: Gagliardi
authors.forename: France
authors.initials: F
authors.lastname: Légaré
authors.forename: Melissa C
authors.initials: MC
authors.lastname: Brouwers
authors.forename: Fiona
authors.initials: F
authors.lastname: Webster
authors.forename: David
authors.initials: D
authors.lastname: Wiljer
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Badley
authors.forename: Sharon
authors.initials: S
authors.lastname: Straus
mesh_terms: D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008962:Models, Theoretical; D010358:Patient Participation / Q000379:methods; D018802:Patient-Centered Care; D000078202:Systematic Reviews as Topic; D057170:Translational Research, Biomedical