title: Prescribing antidepressants for depression: time to be dimensional and inclusive.
abstract: The article by Middleton and Moncrieff questions the role of antidepressants in treating depression on both philosophical and practical grounds; namely that depression isn't a brain disease to be treated by a drug and that antidepressants are ineffective except as placebos. We argue that their stance is unhelpful and factually incorrect and that a more dimensional and integrative approach is needed in order to be able to best tailor treatment to individual needs. This involves a personalised assessment of the likely benefits and risks of both psychological and drug approaches when recommending treatment for someone with depression.
authors.affiliation: Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK. ian.anderson@manchester.ac.uk
authors.forename: Ian M
authors.initials: IM
authors.lastname: Anderson
authors.forename: Peter M
authors.initials: PM
authors.lastname: Haddad
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000628:therapy*; D006801:Humans; D011613:Psychotherapy / Q000379:methods* / Q000592:standards; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents