title: [Cytochemical and immunocytochemical characteristics of Meckel's diverticulum with heterotopic rests of pancreatic tissue].
abstract: BACKGROUND
  Meckel's diverticulum (MD) is a congenital anomaly of the small intestine. It results from incomplete obliteration and resorption of the proximal omphaloenteric duct connecting yolk sac with primitive gut in the fetal period.
  
  
  METHODS
  A case of 20-year old female with ectopic pancreatic rests in a MD was reported. She was hospitalized with clinical signs of acute appendicitis. During surgery an inflamated Meckel's diverticulum was found and a clinoid resection of the diverticulum was performed. Histologic examination revealed pancreatic tissue in the removed diverticulum. Endocrine cells (EC) were detected with Masson staining and aberrant pancreatic tissue with immunocytochemical LSAB2 method using pan cytokeratin as epithelial marker.
  
  
  CONCLUSIONS
  Most of MD are asymptomatic and accessory finding during laparothomias for different causes, but complications of undiagnozed MD can be serious (diverticulitis, perforation with peritonitis or intestinal obstruction caused by invagination). In unclear cases, additional cytochemical and immunocytochemical diagnostics could be done.
authors.affiliation: Medicinski fakultet, Institut za anatomiju, Nis, Srbija. sneska@medfak.ni.ac.rs
authors.forename: Snezana
authors.initials: S
authors.lastname: Pavlović
authors.forename: Dejan
authors.initials: D
authors.lastname: Janjić
authors.forename: Suncica
authors.initials: S
authors.lastname: Mihajlović
authors.forename: Natalija
authors.initials: N
authors.lastname: Stefanović
authors.forename: Miljana
authors.initials: M
authors.lastname: Pavlović
authors.forename: Goran
authors.initials: G
authors.lastname: Stanojević
authors.forename: Vesna
authors.initials: V
authors.lastname: Stojanović
mesh_terms: D002828:Choristoma / Q000473:pathology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D008467:Meckel Diverticulum / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D010179:Pancreas; D055815:Young Adult
chemical_list: D007633:Keratins