title: MicroRNA biomarkers in lung cancer: MiRacle or quagMiRe?
abstract: MicroRNAs have emerged as novel and important regulators of translation. Besides their biological significance, they are being investigated as potential biomarkers of physiological and pathological states. This review article summarizes current investigations of microRNAs as biomarkers in lung cancer. The promises and pitfalls of this exciting new investigational avenue are highlighted.
authors.affiliation: Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY 14228, USA. sai.yendamuri@roswellpark.org
authors.forename: Sai
authors.initials: S
authors.lastname: Yendamuri
authors.forename: Robert
authors.initials: R
authors.lastname: Kratzke
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D055088:Early Detection of Cancer; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000473:pathology; D035683:MicroRNAs / Q000032:analysis*; D046228:Microarray Analysis; D015596:Nutrition Assessment; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D014408:Biomarkers, Tumor; D035683:MicroRNAs