title: Seborrhoeic dermatitis.
abstract: BACKGROUND
  Seborrhoeic dermatitis affects at least 10% of the population. Malassezia (Pityrosporum) ovale is thought to be the causative organism, and causes inflammation by still poorly defined mechanisms. Seborrhoeic dermatitis tends to relapse after treatment.
  
  
  METHODS
  We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of topical treatments for seborrhoeic dermatitis of the scalp in adults? What are the effects of topical treatments for seborrhoeic dermatitis of the face and body in adults? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
  
  
  RESULTS
  We found 12 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
  
  
  CONCLUSIONS
  In this systematic review we present information relating to the effectiveness and safety of the following interventions: bifonazole, emollients, ketoconazole, lithium succinate, selenium sulphide, tar shampoo, terbinafine, and topical corticosteroids (betamethasone valerate, clobetasol propionate, clobetasone butyrate, hydrocortisone, mometasone furoate).
authors.affiliation: Centro Studi GISED, Bergamo, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Naldi
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D001624:Betamethasone Valerate / Q000627:therapeutic use; D012628:Dermatitis, Seborrheic / Q000188:drug therapy; D004643:Emollients / Q000627:therapeutic use; D006203:Hair Preparations / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D012720:Severity of Illness Index; D014486:United States Food and Drug Administration
chemical_list: D000935:Antifungal Agents; D004643:Emollients; D006203:Hair Preparations; D001624:Betamethasone Valerate; D006854:Hydrocortisone