title: Treatment of recurrent head and neck carcinoma involving the carotid artery: carotid reconstruction with ePTFE graft.
abstract: The aim of our study is to investigate the feasibility of reconstructing the carotid artery using expanded polytetraflouroethylene (ePTFE) in patients with recurrent head and neck carcinoma involving the carotid artery. Ten patients, who had recurrent head and neck carcinoma involving the carotid artery, received carotid artery resection and reconstruction with ePTFE, tissue defects were repaired by pectoralis major myocutaneous flap. Results show that eight patients did not present any vascular and neurologic complications. One patient presented slight hemiparesis, another patient developed wound infection and pharyngocutaneous fistula. The mean follow-up period was 33.1 ± 16.0 months. The 2-year survival rate was 50% (5/10), and there was one patient who survived for 60 months without locoreginal recurrence or distant metastasis. En bloc resection of tumor and involved carotid-associated ePTFE reconstruction provide effective improvement in the locoregional control of the recurrent head and neck carcinoma. The pedicle pectoralis major myocutaneous flap can provide not only wound bed with affluent blood supply for the vascular grafts, but also reparation of skin or the tissue defects of oropharynx and hypopharynx.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Institute of Otology, the Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China.
authors.forename: Xiang-bo
authors.initials: XB
authors.lastname: He
authors.forename: Jing-jia
authors.initials: JJ
authors.lastname: Li
authors.forename: Yue-hong
authors.initials: YH
authors.lastname: Chen
authors.forename: Chang
authors.initials: C
authors.lastname: Shu
authors.forename: Qing-lai
authors.initials: QL
authors.lastname: Tang
authors.forename: Xin-ming
authors.initials: XM
authors.lastname: Yang
mesh_terms: D000368:Aged; D001807:Blood Vessel Prosthesis; D002339:Carotid Arteries / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D011138:Polytetrafluoroethylene; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D011138:Polytetrafluoroethylene