title: [Treatment of behavioral disorders by risperidone in children with autism].
abstract: OBJECTIVE
  To study the effect of risperidone treatment on behavioral disorders in children with autism.
  
  
  METHODS
  Forty children with behavioral disorders (aged from 5 to 12 years) were treated with risperidone for 8 weeks. The behavioral symptoms were evaluated by the Clinical Global Impression (CGI) and the Autism Treatment Evaluation Checklist (ATEC) before and after the treatment. The adverse events related to risperidone treatment were observed.
  
  
  RESULTS
  The score of severity of illness and the ATEC total scores were significantly reduced 8 weeks after risperidone treatment. Besides the social intercourse ability, great improvements have been shown on the verbal communication, apperception and behavioural symptoms by the ATEC. No severe adverse events related to risperidone treatment were observed.
  
  
  CONCLUSIONS
  Risperidone can significantly improve the behavioral disorders in children with autism and is well-tolerated.
authors.affiliation: Nanning Rehabiliation Center for Disabled Children, Nanning 530003, China. wbinyuan17@163.com
authors.forename: Bin-Yuan
authors.initials: BY
authors.lastname: Wei
authors.forename: Fei
authors.initials: F
authors.lastname: Huang
authors.forename: Xiao-Tian
authors.initials: XT
authors.lastname: Qin
authors.forename: Qiao-Qi
authors.initials: QQ
authors.lastname: Liang
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001321:Autistic Disorder / Q000188:drug therapy* / Q000523:psychology; D002648:Child; D002653:Child Behavior Disorders / Q000188:drug therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone