title: Combined large cell neuroendocrine carcinoma and spindle cell carcinoma of the lung.
abstract: Pleomorphic carcinomas of the lung are rare malignant biphasic tumors composed of carcinomatous and sarcomatous components. The carcinomatous component is usually an adenocarcinoma or a squamous cell carcinoma, and the sarcomatous component is usually a spindle cell carcinoma. Recently, we encountered two patients who underwent surgery for pleomorphic carcinoma whose carcinomatous component was large cell neuroendocrine carcinoma.
authors.affiliation: Department of General Thoracic Surgery, National Hospital Organization Tokyo Medical Center, Meguro-ku, Tokyo 152-8902, Japan. tgoto@ntmc.hosp.go.jp
authors.forename: Taichiro
authors.initials: T
authors.lastname: Goto
authors.forename: Arafumi
authors.initials: A
authors.lastname: Maeshima
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Kato
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D002277:Carcinoma / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D018287:Carcinoma, Large Cell / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D011013:Pneumonectomy / Q000379:methods; D011859:Radiography
chemical_list: D014408:Biomarkers, Tumor