title: Green and economical production of propionic acid by Propionibacterium freudenreichii CCTCC M207015 in plant fibrous-bed bioreactor.
abstract: Propionic acid production by Propionibacterium freudenreichii from molasses and waste propionibacterium cells was studied in plant fibrous-bed bioreactor (PFB). With non-treated molasses as carbon source, 12.69 ± 0.40 g l(-1) of propionic acid was attained at 120 h in free-cell fermentation, whereas the PFB fermentation yielded 41.22 ± 2.06 g l(-1) at 120 h and faster cells growth was observed. In order to optimize the fermentation outcomes, fed-batch fermentation was performed with hydrolyzed molasses in PFB, giving 91.89 ± 4.59 g l(-1) of propionic acid at 254 h. Further studies were carried out using hydrolyzed waste propionibacterium cells as substitute nitrogen source, resulting in a propionic acid concentration of 79.81 ± 3.99 g l(-1) at 302 h. The present study suggests that the low-cost molasses and waste propionibacterium cells can be utilized for the green and economical production of propionic acid by P. freudenreichii.
authors.affiliation: State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing 210009, PR China.
authors.forename: Xiaohai
authors.initials: X
authors.lastname: Feng
authors.forename: Fei
authors.initials: F
authors.lastname: Chen
authors.forename: Hong
authors.initials: H
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Wu
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Sha
authors.initials: S
authors.lastname: Li
authors.forename: Pingkai
authors.initials: P
authors.lastname: Ouyang
mesh_terms: D019149:Bioreactors; D005285:Fermentation; D010944:Plants / Q000378:metabolism*; D011422:Propionates / Q000378:metabolism*; D011424:Propionibacterium / Q000378:metabolism*
chemical_list: D011422:Propionates; C029658:propionic acid