title: Unusual manifestation of cutaneous toxoplasmosis in a HIV-positive patient.
abstract: We report a case of unusual cutaneous toxoplasmosis manifestation in a HIV-positive patient. He presented with hard and painful nodular lesions on the arms, hands and chest. Serology tests for anti-Toxoplasma antibody were negative. However, histopathologic examination of the lesion revealed foci of macrophages containing crescent-shaped organisms resembling the zoites of the protozoan parasite Toxoplasma gondii. Ultrastructure examination under electron microscopy and PCR confirmed the organism as T. gondii.
authors.affiliation: Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. fongmy@um.edu.my
authors.forename: M Y
authors.initials: MY
authors.lastname: Fong
authors.forename: K T
authors.initials: KT
authors.lastname: Wong
authors.forename: M
authors.initials: M
authors.lastname: Rohela
authors.forename: L H
authors.initials: LH
authors.lastname: Tan
authors.forename: K
authors.initials: K
authors.lastname: Adeeba
authors.forename: Y Y
authors.initials: YY
authors.lastname: Lee
authors.forename: Y L
authors.initials: YL
authors.lastname: Lau
mesh_terms: D000913:Antibodies, Protozoan / Q000097:blood; D001132:Arm / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006225:Hand / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012867:Skin / Q000473:pathology; D012876:Skin Diseases, Parasitic / Q000175:diagnosis* / Q000473:pathology*; D013909:Thorax / Q000473:pathology; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000473:pathology*
chemical_list: D000913:Antibodies, Protozoan