title: [Non-alcoholic fatty liver disease. How and who to screen].
abstract: Non-alcoholic fatty acid disease (NAFLD) can develop in the context of multiple processes but the main etiologic association is undoubtedly with insulin resistance syndrome. The present review aims to provide a systematic diagnostic approach that should include the following basic elements: a) a suspected diagnosis of NAFLD, including confirmation of abstinence from alcohol, exclusion of other potential causes of liver steatosis and diagnosis of potential associated diseases; b) diagnosis of insulin resistance; c) diagnosis of potential associated diseases; d) adequate evaluation of vascular risk; e) diagnosis of the type and localization of fat, and finally, f) evaluation of the severity of NAFLD, which can be performed through invasive and non-invasive techniques.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, España.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Terán Lantarón
authors.forename: Javier
authors.initials: J
authors.lastname: Crespo García
mesh_terms: D000465:Algorithms; D050197:Atherosclerosis / Q000453:epidemiology; D015415:Biomarkers; D050218:Body Fat Distribution; D015897:Comorbidity; D054459:Elasticity Imaging Techniques; D005234:Fatty Liver / Q000139:chemically induced / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D008103:Liver Cirrhosis / Q000209:etiology / Q000473:pathology; D008111:Liver Function Tests; D008403:Mass Screening / Q000379:methods; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D065626:Non-alcoholic Fatty Liver Disease; D018579:Patient Selection; D011237:Predictive Value of Tests; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D008055:Lipids