title: [Effect of integrative medical therapy on the prognosis of patients suffering from yin syndrome type acute ischemic stroke].
abstract: OBJECTIVE
  To observe the effect of integrative medical therapy on the prognosis of patients suffering from yin syndrome type acute ischemic stroke (YS-AIS).
  
  
  METHODS
  A multi-center, prospective, random and parallel controlled clinical trial was carried on 606 patients of YS-AIS. Excepting the 15 patients being excluded and dropped out in the trial period, all patients were assigned to the treatment group (274 patients) treated with integrated medical protocol (i. e. Chinese medical therapy plus conventional Western medical treatment), and the control group (263 patients) treated with conventional Western medical treatment plus placebo. Patients' quality of life (QOL) and their disability level were assessed by scoring based on SS-QOL and modified Rankin scale (mRS) respectively at the terminal of the 21-day treatment (T1) and at the ends of 60-day (T2) and 90-day (T3) following-ups.
  
  
  RESULTS
  Patients' disability level, showed by mRS scores, was not significantly different between the two groups at T1 and T2 (P > 0.05), but with significant difference at T3 (P < 0.05). The recovery in the treatment group were more significant. Although the SS-QOL scores showed no statistical significant difference between groups (P > 0.05), improvement of QOL could be seen in the treatment group and the difference between groups was more significant as the time went by.
  
  
  CONCLUSIONS
  Integrative medical therapy could reduce the severe disability rate in patients after YS-AIS, and showed an improving trend on patients' QOL at T3.
authors.affiliation: Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Wang
authors.forename: Ye-Feng
authors.initials: YF
authors.lastname: Cai
authors.forename: Jian-Wen
authors.initials: JW
authors.lastname: Guo
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D055048:Integrative Medicine; D007511:Ischemia / Q000628:therapy*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D020521:Stroke / Q000175:diagnosis / Q000628:therapy*