title: Complete genome sequence of the hemotrophic Mycoplasma suis strain KI3806.
abstract: Mycoplasma suis, a member of the hemotrophic mycoplasma (HM) group, parasitize erythrocytes of pigs. Increasing evidence suggests that M. suis is also a zoonotic agent. Highly pathogenic strains of M. suis (e.g., M. suis KI3806) have been demonstrated to invade erythrocytes. This complete sequenced and manually annotated genome of M. suis KI3806 is the first available from this species and from the HM group. The DNA was isolated from blood samples of experimentally infected pigs due to the lack of an in vitro cultivation system. The small circular chromosome of 709,270 bp, encoding an unexpectedly high number of hypothetical proteins and limited transport and metabolic capacities, could reflect the unique lifestyle of HM on the surface of erythrocytes.
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse Faculty, University Zurich, 8057 Zurich, Switzerland.
authors.forename: Joern
authors.initials: J
authors.lastname: Oehlerking
authors.forename: Michael
authors.initials: M
authors.lastname: Kube
authors.forename: Kathrin M
authors.initials: KM
authors.lastname: Felder
authors.forename: Denise
authors.initials: D
authors.lastname: Matter
authors.forename: Max M
authors.initials: MM
authors.lastname: Wittenbrink
authors.forename: Sarah
authors.initials: S
authors.lastname: Schwarzenbach
authors.forename: Manuela M
authors.initials: MM
authors.lastname: Kramer
authors.forename: Katharina
authors.initials: K
authors.lastname: Hoelzle
authors.forename: Ludwig E
authors.initials: LE
authors.lastname: Hoelzle
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000145:classification* / Q000235:genetics*; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology
chemical_list: D001426:Bacterial Proteins