title: Essential ingredients for HIV-1 budding.
abstract: HIV-1 engages the cellular ESCRT-III/VPS4 membrane scission machinery for its escape from host cells. Three papers now begin to demystify its mode of action by showing that HIV-1 requires only the transient recruitment of a surprisingly small subset of ESCRT-III components, whose membrane abscission function depends on VPS4 activity.
authors.affiliation: UVHCI UMI 3265 University Joseph Fourier-EMBL-CNRS, 6 rue Jules Horowitz, 38042 Grenoble, France. Electronic address: weissenhorn@embl.fr.
authors.forename: Winfried
authors.initials: W
authors.lastname: Weissenhorn
authors.affiliation: Program in Gene Function and Expression, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: heinrich.gottlinger@umassmed.edu.
authors.forename: Heinrich
authors.initials: H
authors.lastname: Göttlinger