title: Coronary bifurcation lesions treated with simple approach (from the Cordoba & Las Palmas [CORPAL] Kiss Trial).
abstract: The present report compared the incidence of 1-year clinical events in patients with bifurcation lesions that had been treated with a simple approach who were randomized to either a simultaneous final kissing balloon (KB) or an isolated side-branch (SB) balloon post-dilation. From February 2007 to December 2008, 293 patients with all types of Medina bifurcation lesions were enrolled in a prospective study. All patients underwent implantation of a sirolimus- or everolimus-eluting stent across the bifurcation and provisional SB stenting. Patients with no SB ostial compromise or those needing a second stent were excluded from the present study (n = 49). The eligible patients were randomly assigned to treatment with final KB inflation (n = 124, KB group) or isolated balloon after dilation (n = 120, non-KB group). No significant differences were found between the patients from the KB and non-KB groups in terms of age, risk factors, clinical status, or location of the bifurcation lesions. The angiographic data and immediate results were also similar in both groups. Four patients experienced a non-Q-wave acute myocardial infarction in the hospital: three (2%) from the KB group and one (1%) from the non-KB group. Two in-hospital deaths occurred in the non-KB group. Target lesion revascularization was required in 7 patients (3%): 5 from the KB group and 2 from the non-KB group. Late mortality occurred in 3 patients from the KB group and 2 patients from the non-KB group. The incidence of major events at 1 year (death, target lesion revascularization, or acute myocardial infarction) was similar in both groups: 11 (9%) from the KB group and 7 (6%) from the non-KB group (p = NS). In conclusion, no differences in the clinical outcome at 1 year of follow-up were observed between the patients with bifurcation lesions treated with a simple approach and either a simultaneous final KB or an isolated SB balloon post-dilation.
authors.affiliation: Department of Cardiology, Reina Sofia Hospital, University of Córdoba, Instituto Maimónides para la Investigación Biomédica de Córdoba (IMIBIC), Cordoba, Spain. manuelpan@telefonica.net
authors.forename: Manuel
authors.initials: M
authors.lastname: Pan
authors.forename: Alfonso
authors.initials: A
authors.lastname: Medina
authors.forename: José
authors.initials: J
authors.lastname: Suárez de Lezo
authors.forename: Miguel
authors.initials: M
authors.lastname: Romero
authors.forename: Jose
authors.initials: J
authors.lastname: Segura
authors.forename: Pedro
authors.initials: P
authors.lastname: Martín
authors.forename: Javier
authors.initials: J
authors.lastname: Suárez de Lezo
authors.forename: Enrique
authors.initials: E
authors.lastname: Hernández
authors.forename: Francisco
authors.initials: F
authors.lastname: Mazuelos
authors.forename: Alvaro
authors.initials: A
authors.lastname: Moreno
authors.forename: Djordje
authors.initials: D
authors.lastname: Pavlovic
authors.forename: Soledad
authors.initials: S
authors.lastname: Ojeda
authors.forename: Francisco
authors.initials: F
authors.lastname: Toledano
authors.forename: Carmen
authors.initials: C
authors.lastname: Leon
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000401:mortality / Q000628:therapy; D054855:Drug-Eluting Stents; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D011446:Prospective Studies