title: Computed tomography and magnetic resonance imaging appearance of prolactinoma with spheroid-type amyloid deposition.
abstract: We report a rare case of prolactinoma with deposition of amyloid and calcifications. Magnetic resonance imaging and/or computed tomography findings have been described in only a few cases. Possible mechanisms of amyloid deposition and calcification were discussed, and literatures were reviewed. In pituitary adenomas, particularly in prolactinomas, amyloid deposits should be included in the differential diagnosis, when hypointense areas are noted on T2-weighted images. Stippled calcifications in the tumor seem to be another characteristic finding.
authors.affiliation: Department of Radiology, Osaka City University School of Medicine, Osaka, Japan. kaeko@med.osaka-cu.ac.jp
authors.forename: Kaeko
authors.initials: K
authors.lastname: Kitamura
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nakayama
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohata
authors.forename: Kenichi
authors.initials: K
authors.lastname: Wakasa
authors.forename: Yukio
authors.initials: Y
authors.lastname: Miki
mesh_terms: D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis*; D058225:Plaque, Amyloid / Q000175:diagnosis*; D015175:Prolactinoma / Q000175:diagnosis*; D018874:Spheroids, Cellular / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods*