title: [Study on mesh-augmented vaginal reconstructive surgery in treatment of pelvic organ prolapse].
abstract: OBJECTIVE
  To evaluate clinical outcome and complications of mesh-augmented vaginal reconstructive surgery in treatment of pelvic organ prolapse.
  
  
  METHODS
  From Feb 2007 to Jan 2009, mesh-augmented vaginal reconstructive surgery were performed on 66 women with pelvic organ prolapse stage III-IV. Pre and postoperative symptoms, pelvic organ prolapse quantitation (POP-Q) stage and pelvic floor distress inventory-short form 20 (PFDI-20) measurements were studied to assess anatomic and quality-of-life outcome. Operative complications were also analyzed.
  
  
  RESULTS
  Totally 65 patients underwent successful surgeries. The rate of follow-up was 97% (63/65) with a median follow-up of 17.2 months. Subjective cure rate and objective cure rate were both 97% (61/63) at 6 and 12 months after surgeries, 51 women completed PFDI-20 measurements and scores were 102 ± 50 before surgery, 16 ± 21 at 6 months and 15 ± 20 at 12 months. It reached statistical difference when scores were compared before and after surgeries (P < 0.05). Among 66 patients, 2 patients underwent organ injuries, 2 had recurrent prolapse, 4 had mesh-related complications and 1 had severe de novo stress urinary incontinence. Six patients underwent second surgery.
  
  
  CONCLUSIONS
  Mesh-augmented vaginal reconstructive surgery in treatment of pelvic organ prolapsed brought satisfied clinical outcome. The incidence of mesh-related complications was low and secondary operative interventions were effective.
authors.affiliation: Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China. Email: hanjinsong353@sina.com.
authors.forename: Jin-song
authors.initials: JS
authors.lastname: Han
authors.forename: Kun
authors.initials: K
authors.lastname: Zhang
authors.forename: Fu-li
authors.initials: FL
authors.lastname: Zhu
authors.forename: Ying
authors.initials: Y
authors.lastname: Yao
authors.forename: Hua-mao
authors.initials: HM
authors.lastname: Liang
authors.forename: Li-fei
authors.initials: LF
authors.lastname: Zhou
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Guo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007045:Hysterectomy, Vaginal; D007431:Intraoperative Complications / Q000453:epidemiology / Q000601:surgery; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011126:Polypropylenes; D011183:Postoperative Complications / Q000453:epidemiology / Q000601:surgery; D011788:Quality of Life; D012008:Recurrence; D012720:Severity of Illness Index; D013526:Surgical Mesh / Q000009:adverse effects; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery; D014599:Uterus / Q000601:surgery; D014621:Vagina / Q000601:surgery*
chemical_list: D011126:Polypropylenes