title: Vitamin D supplementation in CKD.
abstract: Vitamin D deficiency is common in chronic kidney disease and is associated with increased morbidity and mortality. In addition, vitamin D deficiency in renal disease is associated with serious comorbidities including secondary hyperparathyroidism and cardiovascular disease. Several therapeutic options are available to correct vitamin D deficiency, including nutritional vitamin D, pro-hormones and active hormones. In this review we discuss clinical findings related to the effectiveness of these therapies in chronic kidney disease.
authors.affiliation: Division of Nephrology, Saint Louis University, St. Louis, MO 63110, USA. martinkj@slu.edu
authors.forename: K J
authors.initials: KJ
authors.lastname: Martin
authors.forename: E A
authors.initials: EA
authors.lastname: González
mesh_terms: D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D018450:Disease Progression; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism / Q000627:therapeutic use*; D014808:Vitamin D Deficiency / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism
chemical_list: D014807:Vitamin D