title: Three new fatty acids from the roots of Boehmeria nivea (L.) Gaudich and their antifungal activities.
abstract: Three new unsaturated fatty acids, (Z)-9,10,11-trihydroxy-12-octadecenoic acid (1), (Z)-7,8,9-trihydroxy-10-hexadecenoic acid (2) and (Z)-12-keto-7,8,9-trihydroxy-10-hexadecenoic acid (3) were isolated from the roots of Boehmeria nivea (L.) Gaudich, along with a known unsaturated fatty acid, (E)-8,11,12-trihydroxy-9-octadecenoic acid (4). The structures of the new compounds were established by HR ESI-MS, (1)H, (13)C, 2D ((1)H-(1)H COSY, HSQC, HMBC) NMR experiments. The known compound was identified by a comparison of its spectral data with published references. The three new compounds showed some antifungal activities by agar assay.
authors.affiliation: College of Pharmacy, Soochow University, Suzhou 215123, China.
authors.forename: Qiong-Ming
authors.initials: QM
authors.lastname: Xu
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Liu
authors.forename: Xiao-Ran
authors.initials: XR
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Shi-Lin
authors.initials: SL
authors.lastname: Yang
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification*; D032402:Boehmeria / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000935:Antifungal Agents; D005227:Fatty Acids