title: Sleep hypoventilation syndrome and respiratory failure due to multifocal motor neuropathy with conduction block.
abstract: Sleep hypoventilation syndrome and respiratory failure have been reported in association with a diverse spectrum of neuromuscular disorders. We report a patient with multifocal motor neuropathy with conduction block who presented with sleep hypoventilation, presumably due to bilateral phrenic neuropathy and was initially diagnosed to have obstructive sleep apnea syndrome. Once the correct diagnosis was made the patient was treated successfully with a combination of regular immunoglobulin and bilevel nocturnal ventilation. Delay in the administration of intravenous immunoglobulin resulted in respiratory failure.
authors.affiliation: Cyprus Institute of Neurology and Genetics, 6 International Airport Avenue, P.O. Box 23462, Nicosia 1683, Cyprus. theodore@cing.ac.cy
authors.forename: Theodoros
authors.initials: T
authors.lastname: Kyriakides
authors.forename: Savvas
authors.initials: S
authors.lastname: Papacostas
authors.forename: Eleni
authors.initials: E
authors.lastname: Papanicolaou
authors.forename: Evis
authors.initials: E
authors.lastname: Bagdades
authors.forename: Eleftherios S
authors.initials: ES
authors.lastname: Papathanasiou
mesh_terms: D006801:Humans; D007040:Hypoventilation / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D011115:Polyneuropathies / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D017286:Polysomnography / Q000379:methods; D012131:Respiratory Insufficiency / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D013577:Syndrome