title: [Impact of splenectomy on the hepatic hemodynamics in patients received liver transplantation].
abstract: OBJECTIVE
  To investigate the changes of hepatic hemodynamics in patients with splenectomy plus living donor liver transplantation (LDLT).
  
  
  METHODS
  The data of 66 patients received LDLT from August 2006 to March 2009 were analyzed retrospectively:22 cases received splenectomy with LDLT (splenectomy group) and aged (45 ± 11) years. Forty-four comparable cases received LDLT only in the mean time were selected as control group and aged (44 ± 10) years. Comparative analysis was performed between the two groups with respect to the changes of hepatic hemodynamics after transplantation.
  
  
  RESULTS
  Blood velocity in portal vein in control group and splenectomy group at 1 day before and after the transplantation were (12 ± 2) cm/s vs. (11 ± 3) cm/s, (35 ± 18) cm/s vs. (32 ± 17) cm/s, respectively. Postoperative blood velocity in portal vein in both groups increased significantly than the preoperative level (P < 0.05). Blood flow velocity in right hepatic vein in both groups at 1 week after the treatment were (44 ± 18) cm/s and (31 ± 15) cm/s (P < 0.05), respectively. Blood flow velocity in hepatic artery in both groups 2 weeks after the operation were (18 ± 8) cm/s vs. (26 ± 7) cm/s (P < 0.05) and resistance coefficient of hepatic artery were 0.66 ± 0.13 vs. 0.57 ± 0.12 (P < 0.05), respectively.
  
  
  CONCLUSIONS
  Hepatic hemodynamics in patients received LDLT plus splenectomy is superior to that in patients received LDLT only.
authors.affiliation: Department of Organ Transplantation, the First Central Clinic College, Tianjin Medical University, China.
authors.forename: Ke-Feng
authors.initials: KF
authors.lastname: Liu
authors.forename: Hong
authors.initials: H
authors.lastname: Zheng
authors.forename: Zhong-Yang
authors.initials: ZY
authors.lastname: Shen
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008099:Liver / Q000098:blood supply*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D013156:Splenectomy