title: [Clinical and instrumental characteristics of the gastroesophageal reflux in children with bronchial asthma, possibilities of therapy].
abstract: The group of 141 school-year children with bronchial asthma was examined. The condition of upper gastrointestinal tract was assessed. Gastroesophageal reflux disease was revealed in 94 children (66.7%). Dyspepsia, mucosal damage and changes of 24-hour pH monitoring data were more intensive in acute period of asthma and in children with severe asthma. Acid supression in the complex therapy of gastroesophageal reflux disease permited to minimise symptoms of dyspepsia and improve the pH monitoring data.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Apenchenko
authors.forename: S F
authors.initials: SF
authors.lastname: Gnusaev
authors.forename: D N
authors.initials: DN
authors.lastname: Rozov
authors.forename: I I
authors.initials: II
authors.lastname: Ivanova
mesh_terms: D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications* / Q000188:drug therapy; D002648:Child; D004359:Drug Therapy, Combination; D004947:Esophagus / Q000187:drug effects / Q000473:pathology / Q000502:physiology; D005260:Female; D005744:Gastric Acid / Q000737:chemistry / Q000378:metabolism; D005745:Gastric Acidity Determination / Q000295:instrumentation; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D018670:Monitoring, Ambulatory; D054328:Proton Pump Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D018927:Anti-Asthmatic Agents; D054328:Proton Pump Inhibitors