title: Erratum to: resveratrol and red wine, healthy heart and longevity.
abstract: Resveratrol, a polyphenol phytoalexin, present in red wine and grapes possesses diverse biochemical and physiological properties, including estrogenic, antiplatelet, and anti-inflammatory properties as well as a wide range of health benefits ranging from chemoprevention to cardioprotection. Recently, several studies described resveratrol as an anti-aging compound. This review focuses on the anti-aging aspects of resveratrol, the possible mechanisms of action, and emerging controversy on its life-prolonging ability. It appears that resveratrol can induce the expression of several longevity genes including Sirt1, Sirt3, Sirt4, FoxO1, Foxo3a and PBEF and prevent aging-related decline in cardiovascular function including cholesterol level and inflammatory response, but it is unable to affect actual survival or life span of mice.
authors.affiliation: Cardiovacular Research Center, University of Connecticut School of Medicine, Farmington, CT 06030-1110, USA. ddas@neuron.uchc.edu
authors.forename: Dipak K
authors.initials: DK
authors.lastname: Das
authors.forename: Subhendu
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Diptarka
authors.initials: D
authors.lastname: Ray
mesh_terms: D000375:Aging / Q000187:drug effects; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002316:Cardiotonic Agents / Q000737:chemistry / Q000494:pharmacology*; D006304:Health Status; D006321:Heart / Q000187:drug effects*; D006801:Humans; D008136:Longevity / Q000187:drug effects; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry / Q000494:pharmacology*; D014920:Wine
chemical_list: D000975:Antioxidants; D002316:Cardiotonic Agents; D013267:Stilbenes; D000077185:Resveratrol