title: [Management of a retroperitoneal paraganglioma].
abstract: Paragangliomas are rare tumors arising from extraadrenal chromaffin cells. We report a 43-year-old man who presented with abdominal pain. An abdominal computed tomography scan revealed a large retroperitoneal mass. During an endoscopic biopsy of this tumor, the patient experienced marked hemodynamic fluctuations with tachycardia and high blood pressure, and an extraadrenal pheochromocytoma was suspected. Measurements of plasma and urinary catecholamines and urinary total metanephrines ruled in the diagnosis. Echocardiography disclosed acute myocardial dysfunction that returned to normal after surgical resection of the paraganglioma. This report also underlines the importance of the anesthetic preparation and monitoring around the surgical procedure and the need of a long-term follow-up to detect malignant paraganglioma in the absence of histological criteria of benign tumor.
authors.affiliation: Pôle d'anesthésie réanimation, CHU, place Victor-Pauchet, 80054 Amiens, France. badaoui.rachid@chu-amiens.fr
authors.forename: R
authors.initials: R
authors.lastname: Badaoui
authors.forename: J
authors.initials: J
authors.lastname: Delmas
authors.forename: A
authors.initials: A
authors.lastname: Dhahri
authors.forename: Y
authors.initials: Y
authors.lastname: Mahjoub
authors.forename: M
authors.initials: M
authors.lastname: Fumery
authors.forename: M
authors.initials: M
authors.lastname: Riboulot
authors.forename: J-M
authors.initials: JM
authors.lastname: Regimbeau
authors.forename: H
authors.initials: H
authors.lastname: Dupont
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D015415:Biomarkers / Q000097:blood / Q000652:urine; D001706:Biopsy; D002395:Catecholamines / Q000097:blood / Q000652:urine; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008676:Metanephrine / Q000652:urine; D010235:Paraganglioma / Q000175:diagnosis / Q000601:surgery; D010673:Pheochromocytoma / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000601:surgery* / Q000652:urine; D012186:Retroperitoneal Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000601:surgery* / Q000652:urine; D012187:Retroperitoneal Space / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D002395:Catecholamines; D008676:Metanephrine