title: Electromagnetic therapy for treating venous leg ulcers.
abstract: BACKGROUND
  Leg ulceration is a common, chronic, recurring condition. The estimated prevalence of leg ulcers in the UK population is 1.5 to 3 per 1000. Venous ulcers (also called stasis or varicose ulcers) comprise 80% to 85% of all leg ulcers. Electromagnetic therapy (EMT) is sometimes used as a treatment to assist the healing of chronic wounds such as venous leg ulcers.
  
  
  OBJECTIVE
  To assess the effects of EMT on the healing of venous leg ulcers.
  
  
  METHODS
  For this second update, Cochrane Wounds Group Specialised Register (searched 16 February 2011); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 1); Ovid MEDLINE (1950 to February Week 1 2011); Ovid MEDLINE (In-Process & Other Non-Indexed Citations February 15, 2011); Ovid EMBASE (1980 to 2011 Week 06); and EBSCO CINAHL (1982 to 11 February 2011). We applied no date or language restrictions.
  
  
  METHODS
  Randomised controlled trials comparing EMT with sham-EMT or other treatments.
  
  
  METHODS
  At least two review authors independently scrutinised search results and obtained full reports of potentially eligible studies for further assessment. We extracted and summarised details of eligible studies using a data extraction sheet, and made attempts to obtain missing data by contacting study authors. A second review author checked data extraction, and we resolved disagreements after discussion between review authors.
  
  
  RESULTS
  Three randomised controlled trials (RCTs) of variable quality involving 94 people were included in the original review; subsequent updates have identified no new trials. All the trials compared the use of EMT with sham-EMT. In the two trials that reported healing rates; one small trial (44 participants) reported that significantly more ulcers healed in the EMT group than the sham-EMT group however this result was not robust to different assumptions about the outcomes of participants who were lost to follow up. The second trial that reported numbers of ulcers healed found no significant difference in healing. The third trial was also small (31 participants) and reported significantly greater reductions in ulcer size in the EMT group however this result may have been influenced by differences in the prognostic profiles of the treatment groups.
  
  
  CONCLUSIONS
  There is no high quality evidence that electromagnetic therapy increases the rate of healing of venous leg ulcers, and further research is needed.
authors.affiliation: Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, 50603.
authors.forename: Zoriah
authors.initials: Z
authors.lastname: Aziz
authors.forename: Nicky A
authors.initials: NA
authors.lastname: Cullum
authors.forename: Kate
authors.initials: K
authors.lastname: Flemming
mesh_terms: D006801:Humans; D055909:Magnetic Field Therapy / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D014647:Varicose Ulcer / Q000628:therapy*; D014945:Wound Healing