title: [Analysis of risk factors of fatal outcome in pregnant and puerperant patients with severe H1N1 influenza].
abstract: As well as previous epidemics and pandemias of influenza, the 2009 H1N1 influenza pandemia increases the risk of severe illness in pregnant. Data were reported for 28 pregnant and 2 postpartum women who have been hospitalized in ICUs of Krasnodar Region with H1N1 influenza diagnosis. The laboratory tests for H1N1 were negative in 53.3% of suspected cases of H1N1 influenza (16 of 30). The major lethal risk factor in pregnant with H1N1 influenza is a development of septic shock with low PaO2\FiO2 ratio (less than 140) and high Murray's Acute Lung Injury Score (higher than 2.5). High Apache II, Apache III, SAPS 2, SAPS 3 and SOFA scores are the additional lethal risk factors. Lethal outcomes were more frequent in the end of the second trimester of pregnancy.
authors.forename: I B
authors.initials: IB
authors.lastname: Zabolotskikh
authors.forename: G A
authors.initials: GA
authors.lastname: Penzhoian
authors.forename: T S
authors.initials: TS
authors.lastname: Musaeva
authors.forename: S I
authors.initials: SI
authors.lastname: Goncharenko
mesh_terms: D000328:Adult; D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000401:mortality / Q000628:therapy / Q000821:virology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000401:mortality / Q000628:therapy / Q000821:virology; D011264:Pregnancy Trimesters; D012131:Respiratory Insufficiency / Q000401:mortality / Q000628:therapy / Q000821:virology; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult