title: [Growth factors are markers of placental insufficiency in third-trimester miscarriage].
abstract: The paper characterizes placental growth factors in the third trimester of pregnancy. The placental expression of vascular endothelial growth factor (VEGF) and transforming growth factor-beta2 (TGFbeta2) was studied in miscarriage after 34-37 weeks pregnancy and during term labor. Chronic placental insufficiency was diagnosed in miscarriage. The expression of VEGF and TGFbeta2 with trophoblast and decidual cells was decreased in miscarriage as compared with that during uncomplicated pregnancy. The growth factors under study are markers of chronic placental insufficiency in third-trimester miscarriage.
authors.forename: R A
authors.initials: RA
authors.lastname: Kuznetsova
authors.forename: O V
authors.initials: OV
authors.lastname: Rachkova
authors.forename: L V
authors.initials: LV
authors.lastname: Kulida
authors.forename: L V
authors.initials: LV
authors.lastname: Kruglova
authors.forename: L P
authors.initials: LP
authors.lastname: Peretiatko
mesh_terms: D000022:Abortion, Spontaneous / Q000378:metabolism* / Q000473:pathology; D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D002908:Chronic Disease; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D010927:Placental Insufficiency / Q000378:metabolism* / Q000473:pathology; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000378:metabolism*; D053781:Transforming Growth Factor beta2 / Q000096:biosynthesis*; D042461:Vascular Endothelial Growth Factor A / Q000096:biosynthesis*
chemical_list: D015415:Biomarkers; D053781:Transforming Growth Factor beta2; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A