title: Mathematical descriptions of biochemical networks: stability, stochasticity, evolution.
abstract: In this paper, we review some fundamental aspects, as well as some new developments, in the emerging field of network biology. The focus of attention is placed on mathematical approaches to conceptual modeling of biomolecular networks with special emphasis on dynamic stability, stochasticity and evolution.
authors.affiliation: National Cancer Institute, 6130 Executive Blvd., EPN, Rm 3108, Rockville, MD 20852, USA. sr212a@nih.gov
authors.forename: Simon
authors.initials: S
authors.lastname: Rosenfeld
mesh_terms: D001669:Biochemical Phenomena; D005075:Biological Evolution; D060833:Cellular Microenvironment; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D017711:Nonlinear Dynamics; D013269:Stochastic Processes; D049490:Systems Biology / Q000379:methods*