title: [Determination of free fatty-acid carrier protein by enzyme immunoassay and non-instrumental method in acute coronary syndrome].
abstract: The purpose of the investigation was to study changes in and relationships with the clinical and echocardiographic parameters in the serum level of cardiac fatty-acid carrier protein (cFACP) with acute myocardial infarction (MI), as well as the efficiency of non-instrumental determination of the content of cFACP, by using the test systems "CardioFACP" in the diagnosis of acute MI. The investigation showed the high diagnostic value of cFACP as the earliest marker of acute MI during both its enzyme immunoassay and non-instrumental determination. The sensitivity of the test system "CardioFACP" was found to be greater than that of the troponin test within the first hours of acute MI. The findings support the specific features of the kinetics of cFACP and its sensitivity in detecting cardiomyocyte lesions, on the one hand, and determine perspectives for its use to diagnose MI and reocclusions of the infarction-related coronary artery after reperfusion therapy, on the other.
authors.forename: V V
authors.initials: VV
authors.lastname: Riabov
authors.forename: T E
authors.initials: TE
authors.lastname: Suslova
authors.forename: V A
authors.initials: VA
authors.lastname: Markov
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood*; D000328:Adult; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
chemical_list: D050556:Fatty Acid-Binding Proteins; D011933:Reagent Kits, Diagnostic