title: Cutaneous hyalohyphomycosis caused by Paecilomyces lilacinus successfully treated by oral voriconazole and nystatin packing.
abstract: Paecilomyces lilacinus causes multiple diseases in humans, especially in immunocompromised patients. Cutaneous infections are the second most commonly encountered circumstance. We describe a woman with liver cirrhosis with hemorrhagic, bullous, ulcerative leg lesions caused by Paecilomyces lilacinus. The lesions improved after treatment with oral voriconazole and topical nystatin powder. We also reviewed previously reported cases of cutaneous P. lilacinus infection that were treated by oral voriconazole.
authors.affiliation: Department of Dermatology, Mackay Memorial Hospital, Zhongshan District, Taipei, Taiwan.
authors.forename: Ching-Yu
authors.initials: CY
authors.lastname: Huang
authors.forename: Pei-Lun
authors.initials: PL
authors.lastname: Sun
authors.forename: Hsiang-Kuang
authors.initials: HK
authors.lastname: Tseng
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage; D003881:Dermatomycoses / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D009761:Nystatin / Q000008:administration & dosage*; D010143:Paecilomyces / Q000187:drug effects / Q000302:isolation & purification*; D011743:Pyrimidines / Q000008:administration & dosage*; D012883:Skin Ulcer / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D009761:Nystatin; D065819:Voriconazole