title: Influence of donor cytomegalovirus (CMV) status on severity of viral reactivation after allogeneic stem cell transplantation in CMV-seropositive recipients.
abstract: We investigated the role of donor cytomegalovirus (CMV) serostatus on reactivation of CMV infection in CMV-infected transplant recipients. Reactivation of CMV infection occurred more frequently in patients receiving a CMV-positive graft but was less severe than in patients receiving a CMV-negative graft. These data suggest roles for both virus as well as CMV-specific immunity present in the graft.
authors.affiliation: Deparment of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Floor L
authors.initials: FL
authors.lastname: Pietersma
authors.forename: Suzanne
authors.initials: S
authors.lastname: van Dorp
authors.forename: Monique C
authors.initials: MC
authors.lastname: Minnema
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kuball
authors.forename: Ellen
authors.initials: E
authors.lastname: Meijer
authors.forename: Rob
authors.initials: R
authors.lastname: Schuurman
authors.forename: Debbie
authors.initials: D
authors.lastname: van Baarle
mesh_terms: D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D033581:Stem Cell Transplantation; D014019:Tissue Donors; D014775:Virus Activation