title: [What's new in the treatment of seminomas?].
abstract: Pure testicular seminoma is a rare disease with an excellent prognosis. Its management is controversial. In stage I disease, several treatment options are considered. Those are radiation therapy alone, chemotherapy alone or active surveillance, which is becoming increasingly popular. For more advanced stages, treatment is based on chemotherapy with or without radiation therapy. In this article, we review thoroughly the existing literature and recent recommendations the various treatment options, their advantages and disadvantages in different stages of the disease.
authors.affiliation: Service de radio-oncologie, CHU vaudois, Lausanne, Suisse.
authors.forename: N
authors.initials: N
authors.lastname: Boujelbene
authors.forename: M
authors.initials: M
authors.lastname: Ozsahin
authors.forename: K
authors.initials: K
authors.lastname: Khanfir
authors.forename: D
authors.initials: D
authors.lastname: Azria
authors.forename: R O
authors.initials: RO
authors.lastname: Mirimanoff
authors.forename: A
authors.initials: A
authors.lastname: Zouhair
mesh_terms: D000328:Adult; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000627:therapeutic use; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000378:metabolism; D003131:Combined Modality Therapy; D019468:Disease Management; D006801:Humans; D015182:Lymphatic Irradiation; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D016609:Neoplasms, Second Primary / Q000209:etiology; D009919:Orchiectomy; D009944:Organoplatinum Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods; D012189:Retrospective Studies; D012307:Risk Factors; D018239:Seminoma / Q000453:epidemiology / Q000378:metabolism / Q000473:pathology / Q000556:secondary / Q000628:therapy*; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D035703:Therapies, Investigational; D055815:Young Adult
chemical_list: D018906:Antineoplastic Agents, Alkylating; D018997:Chorionic Gonadotropin, beta Subunit, Human; D009944:Organoplatinum Compounds