title: [Thymoma which is detected with a cough derived from pulmonary invasion; report of a case].
abstract: A 83-year-old female was referred to our hospital for investigation of a persistent cough. A chest X-ray showed enlargement of the mediastinum. Computed tomography of the chest showed an anterior mediastinal mass with a maximal diameter of 6.5 cm, which had invasion to the lung. The patient underwent thymothymectomy combined resections of the lung, pericardium, and left innominate vein through a median sternotomy. Histological examination of the resected tumor revealed a World Health Organization (WHO) classification type B3 thymoma with infiltration into the lung. There were no infiltrations of the tumor into the pericardium and the innominate vein. A persistent cough disappeared after surgery. No adjuvant chemotherapy was performed. She is still free from disease with a follow-up period of 4 months. We report a rare case of thymoma detected with a persistent cough derived from pulmonary invasion.
authors.affiliation: Department of Surgery, Hakodate Medical Hospital, Hakodate, Japan.
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Okubo
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takahashi
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Takanori
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Motoshi
authors.initials: M
authors.lastname: Kanai
mesh_terms: D000369:Aged, 80 and over; D003371:Cough / Q000209:etiology*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology; D009361:Neoplasm Invasiveness; D013945:Thymoma / Q000175:diagnosis* / Q000473:pathology; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000473:pathology