title: Carbamate prodrug concept for hydroxamate HDAC inhibitors.
authors.affiliation: Department of Pharmaceutical Chemistry, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle/Saale, Germany.
authors.forename: Sonja
authors.initials: S
authors.lastname: Schlimme
authors.forename: Alexander-Thomas
authors.initials: AT
authors.lastname: Hauser
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Carafa
authors.forename: Ralf
authors.initials: R
authors.lastname: Heinke
authors.forename: Srinivasaraghavan
authors.initials: S
authors.lastname: Kannan
authors.forename: Diana A
authors.initials: DA
authors.lastname: Stolfa
authors.forename: Saverio
authors.initials: S
authors.lastname: Cellamare
authors.forename: Angelo
authors.initials: A
authors.lastname: Carotti
authors.forename: Lucia
authors.initials: L
authors.lastname: Altucci
authors.forename: Manfred
authors.initials: M
authors.lastname: Jung
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Sippl
mesh_terms: D002219:Carbamates / Q000737:chemistry*; D003198:Computer Simulation; D056572:Histone Deacetylase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006655:Histone Deacetylases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D006877:Hydroxamic Acids / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011355:Prodrugs / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D002219:Carbamates; D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D011355:Prodrugs; D011994:Recombinant Proteins; D006655:Histone Deacetylases