title: Combined exogenous and endogenous catecholamine release associated with Tako-Tsubo like syndrome in a patient with atrio-ventricular block undergoing pace-maker implantation.
abstract: We report the case of a 65-year-old woman with complete atrio-ventricular block who underwent orciprenaline administration and pacemaker implantation. The intervention was complicated by pneumothorax and acute left ventricular systolic dysfunction with typical apical ballooning (Tako-Tsubo like syndrome). The patient was treated with diuretics and calcium-sensitizers and completely recovered. We speculate that both external and internal catecholamine triggered an acute left ventricular impairment with typical Tako-Tsubo features.
authors.forename: Natale Daniele
authors.initials: ND
authors.lastname: Brunetti
authors.forename: Riccardo
authors.initials: R
authors.lastname: Ieva
authors.forename: Michele
authors.initials: M
authors.lastname: Correale
authors.forename: Luisa
authors.initials: L
authors.lastname: De Gennaro
authors.forename: Pier Luigi
authors.initials: PL
authors.lastname: Pellegrino
authors.forename: Ezio
authors.initials: E
authors.lastname: Dioguardi
authors.forename: Girolamo
authors.initials: G
authors.lastname: D'Arienzo
authors.forename: Luigi
authors.initials: L
authors.lastname: Ziccardi
authors.forename: Matteo
authors.initials: M
authors.lastname: Di Biase
mesh_terms: D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage; D000368:Aged; D054537:Atrioventricular Block / Q000628:therapy*; D002395:Catecholamines / Q000378:metabolism*; D004232:Diuretics / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D006801:Humans; D006835:Hydrazones / Q000627:therapeutic use; D009921:Metaproterenol / Q000008:administration & dosage; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D011724:Pyridazines / Q000627:therapeutic use; D000077464:Simendan; D013599:Systole; D054549:Takotsubo Cardiomyopathy / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism
chemical_list: D058666:Adrenergic beta-2 Receptor Agonists; D002395:Catecholamines; D004232:Diuretics; D006835:Hydrazones; D011724:Pyridazines; D000077464:Simendan; D009921:Metaproterenol