title: Disseminated paracoccidioidomycosis (simulating metastatic lung cancer) and Strongyloides stercoralis hyperinfestation in a steroid-treated patient.
abstract: We report a case of disseminated paracoccidioidomycosis, initially suggestive of metastatic lung cancer. The infection was associated with strongyloides hyperinfestation as a result of iatrogenic hypercorticoidism. Examination of a smear prepared from aspirated tracheobronchial secretion and stained by Grocott-methenamine-silver revealed structures consistent with Paracoccidioides brasiliensis and Strongyloides stercoralis. At autopsy, the central nervous system and pulmonary paracoccidioidomycosis, as well as pulmonary strongyloidiasis, were confirmed, without evidence of malignant cells.
authors.affiliation: Postgraduation Program of Pneumology Science, Universidade Federal do Rio Grande do Sul , Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Aline Gehlen
authors.initials: AG
authors.lastname: Dall Bello
authors.forename: Cecília Bittencourt
authors.initials: CB
authors.lastname: Severo
authors.forename: Flávio de Mattos
authors.initials: Fde M
authors.lastname: Oliveira
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Severo
mesh_terms: D000818:Animals; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008168:Lung / Q000382:microbiology / Q000469:parasitology / Q000473:pathology*; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D013902:Radiography, Thoracic; D013256:Steroids / Q000008:administration & dosage; D017171:Strongyloides stercoralis / Q000302:isolation & purification*; D013322:Strongyloidiasis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D007166:Immunosuppressive Agents; D013256:Steroids