title: Synthetic approaches to monofluoroalkenes.
abstract: Monofluoroalkenes are an important fluorinated class of compounds with applications in medicinal chemistry, material sciences and organic chemistry. An overview of methods allowing synthetic access to these fluorinated building blocks is provided. In particular, this critical review, which covers publications up to October 2010, will be divided according to the substitution pattern of the monofluoroalkenes, i.e. di-, tri- or tetra-substituted. Within each group, the various synthetic approaches will be divided according to the reaction type (282 references).
authors.affiliation: Canada Research Chair in Organic and Medicinal Chemistry, Département de chimie, 1045 avenue de la Médecine, Université Laval, Québec (QC), Canada G1V 0A6.
authors.forename: Grégory
authors.initials: G
authors.lastname: Landelle
authors.forename: Maxime
authors.initials: M
authors.lastname: Bergeron
authors.forename: Marc-Olivier
authors.initials: MO
authors.lastname: Turcotte-Savard
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Paquin
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry; D005461:Fluorine / Q000737:chemistry*; D054879:Halogenation; D012451:Safrole / Q000031:analogs & derivatives / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry
chemical_list: D000475:Alkenes; D000480:Alkynes; D013450:Sulfones; D005461:Fluorine; D012451:Safrole; C005746:sulfoxide