title: [Risk factors of severe peripheral corneal ulcers].
abstract: OBJECTIVE
  To evaluate the risk factors of severe peripheral corneal ulcers.
  
  
  METHODS
  Twenty three eyes of 15 patients (9 eyes of 7 men and 14 eyes of 8 women) with severe peripheral corneal ulcers, who were treated during the past 10 years at Keio University Hospital, were reviewed about the original disease, status of ulcer, treatment, and visual prognosis.
  
  
  RESULTS
  Fifteen eyes of 10 patients with Mooren's ulcer, 4 eyes of 3 patients with rheumatoid arthritis, and 4 eyes of 2 patients with Terrien corneal degeneration were included. Mooren's ulcer tends to advance widely. Systemic administration of immunosuppressive and corticosteroidal agents was required in addition to surgical treatment. Visual prognosis was poor in the Mooren's ulcer and perforated cases.
  
  
  CONCLUSIONS
  Mooren's ulcer and perforated cases are risk factors in peripheral corneal ulcer.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. asiancrane0702@yahoo.co.jp
authors.forename: Azu
authors.initials: A
authors.lastname: Suzuki
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Uchino
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kawakita
authors.forename: Shigeto
authors.initials: S
authors.lastname: Shimmura
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D000368:Aged; D003320:Corneal Ulcer / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012307:Risk Factors