title: "Turn-on" FRET-based luminescent iridium(III) probes for the detection of cysteine and homocysteine.
abstract: "Turn-on" FRET-based luminescent probes containing iridium(III) complexes for the detection of Cys and Hcy have been designed and synthesized. The relationship between the steric bulk of the probe and the corresponding emission intensity enhancement towards detection of Cys and Hcy has been studied.
authors.affiliation: Department of Chemistry, State Key Laboratory on Synthetic Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
authors.forename: Hoi-Yan
authors.initials: HY
authors.lastname: Shiu
authors.forename: Man-Kin
authors.initials: MK
authors.lastname: Wong
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003545:Cysteine / Q000032:analysis* / Q000737:chemistry; D015195:Drug Design; D031541:Fluorescence Resonance Energy Transfer; D006710:Homocysteine / Q000032:analysis* / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*; D049408:Luminescent Agents / Q000737:chemistry*
chemical_list: D049408:Luminescent Agents; D006710:Homocysteine; D007495:Iridium; D003545:Cysteine