title: Moving closer to a prognostic DNA methylation signature in colon cancer.
abstract: Although large panels of genes undergoing aberrant CpG island methylation in colorectal cancer have been identified, reliable predictors for clinical management in this tumor type remain elusive. A new DNA methylation signature affecting the extracellular matrix (ECM) pathway has been identified with potential prognostic value in colon cancer.
authors.affiliation: Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain.
authors.forename: F Javier
authors.initials: FJ
authors.lastname: Carmona
authors.forename: Manel
authors.initials: M
authors.lastname: Esteller
mesh_terms: D015331:Cohort Studies; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D018899:CpG Islands; D019175:DNA Methylation; D005109:Extracellular Matrix / Q000378:metabolism; D020869:Gene Expression Profiling; D006801:Humans; D008495:Medical Oncology / Q000379:methods; D011379:Prognosis; D012008:Recurrence