title: Subcutaneous fasciotomy and eradication of superficial venous reflux for chronic and recurrent venous ulcers: mid-term results.
abstract: OBJECTIVE
  Increased intramuscular and subcutaneous tissue pressures are often found in patients with severe chronic venous insufficiency venous ulcer disease. Additional subcutaneous para-tibial fasciotomy promotes early ulcer healing. This study evaluates the mid-term effect of eradication of superficial reflux with additional fasciotomy in patients with increased tissue pressures.
  
  
  METHODS
  Between January 2006 and June 2009, 58 patients underwent fasciotomy. Tissue pressures (intramuscular and subcutaneous) were measured. Sixty-nine limbs with 91 venous ulcers were treated. Mean duration of the venous ulcer was 3.4 years. Underlying disease was post-thrombotic syndrome (PT) in 19 patients (33%, 24 limbs, 27 ulcers) and non-post-thrombotic (non-PT) severe chronic venous insufficiency in 39 (67%, 45 limbs, 64 ulcers). All patients were C6 at the time of surgery. Preoperative tissue pressures were 23.5 ± 6.1 mmHg (intramuscularly) and 9.8 ± 3.2 mmHg (subcutaneously).
  
  
  RESULTS
  Ninety ulcers (99%) healed postoperatively (42 with and 48 without skin grafting). Tissue pressures significantly decreased following surgery and remained low at three months postoperatively. Ten ulcers in six patients recurred six to 20 months postoperatively (11%), resulting in 86.4 actuarial freedom from venous ulcer recurrence at three years following surgery. Four patients (1 non-PT and 3 PT) had re-fasciotomy; all healed initially but two ulcers (2 patients, PT) recurred at 11 and 12 months. Those patients underwent re-fasciotomy, one healed and one recurred six months later.
  
  
  CONCLUSIONS
  Eradication of superficial reflux with additional subcutaneous fasciotomy for chronic and recurrent venous ulcer improves ulcer healing or success of skin grafting. Mid-term results are excellent particularly in patients with non-PT disease. Recurrence is more frequently seen in patients with PT syndrome. In patients with ulcer recurrence and high tissue pressures, re-fasciotomy can be helpful to promote healing, particularly in patients with primary venous disease.
authors.affiliation: Division of Cardiovascular Surgery, Venous Centre, University Hospital of Geneva, 4 rue Gabrielle-Perret-Gentil, CH-1211 Geneva, Switzerland. jan.christenson@hcuge.ch
authors.forename: J T
authors.initials: JT
authors.lastname: Christenson
authors.forename: C
authors.initials: C
authors.lastname: Prins
authors.forename: G
authors.initials: G
authors.lastname: Gemayel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D015995:Prevalence; D040521:Subcutaneous Tissue / Q000473:pathology*; D013577:Syndrome; D013927:Thrombosis / Q000150:complications; D013997:Time Factors; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000628:therapy*; D014648:Varicose Veins / Q000473:pathology; D014656:Vascular Surgical Procedures / Q000379:methods*; D014689:Venous Insufficiency / Q000628:therapy