title: Butyrylcholinesterase activity in young men and women: association with cardiovascular risk factors.
abstract: OBJECTIVE
  We investigated the relationship between butyrylcholinesterase (BuChE) and cardiovascular risk factors in young male and female.
  
  
  METHODS
  The study comprised 1512 healthy subjects, 18-25 years of age. In fasting sera the concentrations of BuChE and cardiovascular risk factors were estimated.
  
  
  RESULTS
  Analysis of variance indicated significant increase in body mass index (BMI), total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL) (p<0.05) and albumin (p<0.001) with BuChE activity increment in males. In females glucose and albumin (p<0.05) increased with BuChE activity. Negative but not significant correlation between BuChE and high-density lipoprotein cholesterol (HDL-C) was detected for both genders.
  
  
  CONCLUSIONS
  The tendency towards overweight in young male could explain our results on BMI as an independent risk factor for higher BuChE in young male. Glucose as an independent risk factor for higher BuChE activity in females indicates that BuChE may be a predictor of diabetes.
authors.affiliation: Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia. stmarina@eunet.rs
authors.forename: Marina
authors.initials: M
authors.lastname: Stojanov
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Stefanović
authors.forename: Gordana
authors.initials: G
authors.lastname: Džingalašević
authors.forename: Slavka
authors.initials: S
authors.lastname: Mandić-Radić
authors.forename: Milica
authors.initials: M
authors.lastname: Prostran
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002091:Butyrylcholinesterase / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000201:enzymology*; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D012044:Regression Analysis; D012307:Risk Factors; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D002091:Butyrylcholinesterase