title: Dapsone-associated methemoglobinemia in a patient with slow NAT2*5B haplotype and impaired cytochrome b5 reductase activity.
authors.affiliation: Department of Medical Sciences, University of Wisconsin-MadisonDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, Florida.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Abouraya
authors.forename: James C
authors.initials: JC
authors.lastname: Sacco
authors.forename: Kristie
authors.initials: K
authors.lastname: Hayes
authors.forename: Sajeve
authors.initials: S
authors.lastname: Thomas
authors.forename: Craig S
authors.initials: CS
authors.lastname: Kitchens
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Trepanier
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D001191:Arylamine N-Acetyltransferase / Q000235:genetics*; D065731:Cytochrome P-450 CYP2C19 / Q000235:genetics; D042966:Cytochrome-B(5) Reductase / Q000235:genetics*; D015786:Cytochromes b5 / Q000235:genetics; D003622:Dapsone / Q000009:adverse effects*; D006239:Haplotypes; D006801:Humans; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000235:genetics
chemical_list: D000890:Anti-Infective Agents; C000594834:CYB5A protein, human; D003622:Dapsone; D015786:Cytochromes b5; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; C583417:CYB5R3 protein, human; D042966:Cytochrome-B(5) Reductase; D001191:Arylamine N-Acetyltransferase; C478900:NAT2 protein, human