title: [Efficacy of neuromidin in alcoholic encephalopathy].
abstract: 40 patients with alcoholic encephalopathy, aged from 30 to 60 years, were enrolled in the study. Patients were divided into two groups: 20 patients in the treatment group received vasoactive, antioxidant treatment and neyromidin in dose 15 mg in solution during 10 days and then in tabs in dose 20 mg three times a day during 2 months. The comparison group included 20 patients receiving only vasoactive and antioxidant treatment. To the end of treatment, the positive changes in the state of patients reflected in the decrease in the number of complaints and neurological symptoms were seen in the treatment group. The significant improvement of MMSE scores, positive changes in P300 latency and amplitude, the increase in scores on physical activity scales, emotional functioning, mental health scales of SF-36 questionnaire were found as well. There were no serious treatment-emergent adverse events.
authors.forename: E R
authors.initials: ER
authors.lastname: Barantsevich
authors.forename: O V
authors.initials: OV
authors.lastname: Posokhina
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Smirnova
authors.forename: K G
authors.initials: KG
authors.lastname: Kurashevich
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications*; D000634:Aminoquinolines / Q000009:adverse effects / Q000627:therapeutic use*; D001927:Brain Diseases / Q000139:chemically induced* / Q000188:drug therapy* / Q000503:physiopathology; D002800:Cholinesterase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D002800:Cholinesterase Inhibitors; C049860:amiridine