title: Temperature-triggered fusion of vesicles composed of right-handed and left-handed amphiphilic helical peptides.
abstract: Vesicles prepared from a mixture of (Sar)(25)-b-(L-Leu-Aib)(6) (SLL) and (Sar)(25)-b-(D-Leu-Aib)(6) (SDL) fused with themselves upon heating to 90 °C. The vesicles also fused with (Sar)(28)-b-(L-Leu-Aib)(8) vesicles upon heating to 90 °C. The temperature-triggered fusion was due to the phase transition of the mixed membrane of SLL and SDL at 90 °C and should be driven by the bending energy stored in the stereocomplex membrane upon taking a vesicular structure.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-Daigaku-Katsura, Kyoto 615-8510, Japan.
authors.forename: Motoki
authors.initials: M
authors.lastname: Ueda
authors.forename: Akira
authors.initials: A
authors.lastname: Makino
authors.forename: Tomoya
authors.initials: T
authors.lastname: Imai
authors.forename: Junji
authors.initials: J
authors.lastname: Sugiyama
authors.forename: Shunsaku
authors.initials: S
authors.lastname: Kimura
mesh_terms: D008561:Membrane Fusion; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D013501:Surface-Active Agents; D013696:Temperature; D044366:Transition Temperature
chemical_list: D010455:Peptides; D013501:Surface-Active Agents