title: Prevalence of the metabolic syndrome in a psychiatric hospital in Mexico.
abstract: BACKGROUND
  The metabolic syndrome (MS) is formed by elevated blood pressure, hypercholesterolemia, hypertriglyceridemía, hyperglycemia and abdominal obesity. Mexico occupies the second place worldwide in prevalence of obesity. It has been reported that the use of psychopharmaceuticals increase the risk of MS.
  
  
  OBJECTIVE
  To detect prevalence of MS in patients with a psychiatric diagnosis with or without psychopharmaceutical treatment.
  
  
  METHODS
  An observational, descriptive study was designed. Informed consent was obtained, enrolling a sample of 216 patients in the six-month period, all of them over 18 years of age. The following variables were measured: blood pressure, weight, height, waist circumference, triglyceride, glucose and high-density lipoprotein serum levels, by colorimetric enzyme assay in Roche analyzer.
  
  
  METHODS
  Student's t-test, and Cochran-Mantel- Haenszel and Fisher's exact test.
  
  
  RESULTS
  A total of 50% of the sample had a waist circumference >88 cm; 10% glycemia superior to 110 mg/dl, 30% triglycerides >150 mg/dl; 14% met the MS criteria. When patients with and without MS were grouped, and glucose and triglycerides were compared, a p 0.0001 was obtained. With a 93.4% confidence interval, the relationship between sedentary life and MS was accepted. Women, aged 40-59 years tended to have MS, with 98.4% CI. The only family background associated to MS was obesity (97.7% CI). There is a positive relationship between MS and the use of typical or atypical antipsychotics. SSRIs are significantly related with MS: p 0.072 and 91.5% confidence interval, benzodiazepines with p 0.073 and 92.7% confidence interval.
  
  
  CONCLUSIONS
  Only 14% of the sample had MS. Psychopharmaceuticals were associated to MS, women between 40 to 59 years having a greater risk.
authors.affiliation: Médico Psiquiatra Secretaría de Salud Hospital Psiquiátrico Fray Bernardino Alvarez Maestria en Salud Pública, Instituto Nacional de Salud Pública. lina.diaz@espm.insp.mx
authors.forename: Lina
authors.initials: L
authors.lastname: Díaz-Castro
authors.forename: Héctor
authors.initials: H
authors.lastname: Cabello-Rangel
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Cuevas-Pineda
authors.forename: Horacio
authors.initials: H
authors.lastname: Reza-Garduño
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Castañeda-González
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006778:Hospitals, Psychiatric; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008800:Mexico; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult