title: [Hepatocellular carcinoma with multiple lung metastasis resulting in long-term disease-free survival by transcatheter arterial infusion chemotherapy of SMANCS].
abstract: The patient was a 61-year-old female with alcoholic liver cirrhosis, who was admitted to our hospital due to elevation of AFP.During the evaluation, both abdominal ultrasound and enhanced abdominal CT revealed a hepatocellular carcinoma measuring 4 cm in the S6-7 region, complicated with an arteriovenous shunt.Additionally, the lung CT examination showed 20 isolated bilateral lung tumors, all of which were less than 1.4 cm in diameter. Following the diagnosis, we performed a transcatheter arterial infusion chemotherapy of SMANCS at 3 mg through the right heptic artery. Thereafter, the AFP level returned to normal. Additionally, the tumors previously observed in both liver and lung, and exhibited by both lung CT and enhanced abdominal MRI, had disappeared.The patient has been in clinical remission more than 10 years to date.
authors.affiliation: Dept. of Internal Medicine, Kin-IKyo Chuo Hospital, Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Koyama
authors.forename: Shingo
authors.initials: S
authors.lastname: Honjo
authors.forename: Ryutaro
authors.initials: R
authors.lastname: Morizono
authors.forename: Tetsu
authors.initials: T
authors.lastname: Goto
authors.forename: Kotaro
authors.initials: K
authors.lastname: Morita
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Daita
authors.forename: Kiminori
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Masahide
authors.initials: M
authors.lastname: Uchizawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Mizuo
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008299:Maleic Anhydrides / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D011137:Polystyrenes / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D009353:Zinostatin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D008299:Maleic Anhydrides; D011137:Polystyrenes; C035755:poly(maleic acid-styrene)neocarzinostatin; D009353:Zinostatin