title: Failure to validate toxicity and outcome biomarkers from the FFCD 2000-05 trial in the MRC CR08 FOCUS trial.
authors.forename: Susan D
authors.initials: SD
authors.lastname: Richman
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Barrett
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Seymour
mesh_terms: D020121:5' Untranslated Regions; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D014408:Biomarkers, Tumor / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics / Q000401:mortality / Q000556:secondary; D018572:Disease-Free Survival; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D010597:Pharmacogenetics; D010641:Phenotype; D011110:Polymorphism, Genetic; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D016019:Survival Analysis; D013940:Thymidylate Synthase / Q000235:genetics*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D020121:5' Untranslated Regions; D014408:Biomarkers, Tumor; D013940:Thymidylate Synthase