title: Diagnostic accuracy of 1.5-T unenhanced whole-heart coronary MR angiography performed with 32-channel cardiac coils: initial single-center experience.
abstract: OBJECTIVE
  To compare the imaging time and image quality obtained with whole-heart coronary magnetic resonance (MR) angiography performed with five- and 32-channel coils in healthy subjects and determine the accuracy of MR angiography performed with 32-channel coils in the detection of obstructive coronary artery disease (CAD).
  
  
  METHODS
  The institutional review board approved the study protocol, and all participants provided written informed consent. The authors studied 10 healthy subjects and 67 patients suspected of having CAD who were scheduled for coronary angiography. Unenhanced 1.5-T coronary MR angiography was performed with five- and 32-channel coils in healthy subjects and with 32-channel coils in patients. Clinically significant CAD was defined as a diameter reduction of at least 50% at coronary angiography. The sensitivity and specificity of coronary MR angiography were calculated.
  
  
  RESULTS
  The mean imaging time was substantially reduced from 12.3 minutes ± 4.2 (standard deviation) with five-channel coils to 6.3 minutes ± 2.2 with 32-channel coils, with equivalent image quality scores. Acquisition of MR angiograms was completed in all 67 patients, with a mean imaging time of 6.2 minutes ± 2.8. The prevalence of CAD in the study population was 58% (39 of the 67 patients). The areas under the receiver operating characteristic curves as determined at vessel- and patient-based analyses were 0.91 and 0.90, respectively; the sensitivity and specificity at vessel-based analysis were 86% and 93%, respectively.
  
  
  CONCLUSIONS
  Whole-heart coronary MR angiography performed at 1.5 T with 32-channel coils permits noninvasive detection of CAD with substantially reduced imaging time. This noninvasive approach can be an alternative to multidetector computed tomographic coronary angiography for ruling out obstructive CAD in patients who have a contraindication to contrast material and in young subjects who are at higher risk from ionizing radiation.
  
  
  BACKGROUND
  http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11101323/-/DC1.
authors.affiliation: Department of Radiology and Cardiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
authors.forename: Motonori
authors.initials: M
authors.lastname: Nagata
authors.forename: Shingo
authors.initials: S
authors.lastname: Kato
authors.forename: Kakuya
authors.initials: K
authors.lastname: Kitagawa
authors.forename: Nanaka
authors.initials: N
authors.lastname: Ishida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakajima
authors.forename: Shiro
authors.initials: S
authors.lastname: Nakamori
authors.forename: Masaki
authors.initials: M
authors.lastname: Ishida
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Miyahara
authors.forename: Masaaki
authors.initials: M
authors.lastname: Ito
authors.forename: Hajime
authors.initials: H
authors.lastname: Sakuma
mesh_terms: D000328:Adult; D019540:Area Under Curve; D016009:Chi-Square Distribution; D000075202:Contraindications; D003287:Contrast Media; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D018810:Magnetic Resonance Angiography / Q000295:instrumentation* / Q000379:methods*; D008297:Male; D012372:ROC Curve; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D003287:Contrast Media