title: [Preoperative preparation of pregnant with hypertension according to state of the autonomic nervous system and circulatory system].
abstract: Pregnancy in patients with hypertension is considered in the spotlight of creation of general adaptation syndrome. According to evidence, when a stable hypertension in pregnant patients with hyper- and eukinetic types of haemodynamics is observed, the response of circulatory system and body fluid compartments has a moderate difference with normal. In pregnant patients with hypertension and a hypokinetic type of haemodynamics and pregnant patients with gestosis developed against the background of eukinetic type of hypertension, a physiological decrease of total peripheral resistance (TPR) is absent, which contributes into interstitial hyperhydration. In pregnant patients with gestosis developed against the background of hypokinetic type of haemodynamics, a pathological rise of TPR occurs, which is followed with a more significant interstitial hyperhydration. A differentiated preoperative preparation of pregnant with hypertension with the calcium antagonists and hydroxyethyl starch solution (130/0,4) favours the conversion of hyper- and hypokinetic types of haemodynamics to eukinetic, forms a physiological type of sympathicotonia and improves the water-salt metabolism.
authors.forename: V A
authors.initials: VA
authors.lastname: Gur'ianov
authors.forename: G N
authors.initials: GN
authors.lastname: Tolmachev
authors.forename: A V
authors.initials: AV
authors.lastname: Volodin
authors.forename: N V
authors.initials: NV
authors.lastname: Marichik
authors.forename: V B
authors.initials: VB
authors.lastname: Nemirovskiĭ
authors.forename: G M
authors.initials: GM
authors.lastname: Pivovarova
authors.forename: N L
authors.initials: NL
authors.lastname: Shepetovskaia
mesh_terms: D000222:Adaptation, Physiological; D001341:Autonomic Nervous System / Q000187:drug effects / Q000502:physiology*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use; D004562:Electrocardiography; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006706:Homeostasis / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D010952:Plasma Substitutes / Q000008:administration & dosage; D011225:Pre-Eclampsia / Q000503:physiopathology / Q000517:prevention & control*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000503:physiopathology; D011300:Preoperative Care / Q000379:methods*
chemical_list: D002121:Calcium Channel Blockers; D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes