title: [Post-radiation mucocele in two patients treated for nasopharyngeal cancer].
abstract: A 30-year-old woman, with a history of nasopharyngeal carcinoma, which was treated by radiotherapy nine years previously, presented with occasional diplopia and recent headaches. A nasopharyngeal biopsy showed no recurrence. The imaging revealed a sphenoidal sinus mucocele. Endoscopic marsupialization of the mucocele allowed clinical improvement. A 56-year-old woman presented, five years after radiotherapy for nasopharyngeal carcinoma, with a fronto-orbital mass. CT-scan revealed a fronto-ethmoidal mucocele. Nasopharyngeal biopsy showed tumour recurrence. Marsupialization of mucocele was performed. Recurrence of the carcinoma was treated by radiotherapy and chemotherapy. Sphenoidal sinus mucocele developing after radiotherapy for nasopharyngeal carcinoma has rarely been reported. CT scan and MRI are useful tools in making the diagnosis. Biopsy is required to diagnose recurrence or associated radio-induced tumor. Endoscopic approach gives good results.
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU Habib-Bourguiba, Sfax, Tunisie. mnejjamalek@gmail.com
authors.forename: M
authors.initials: M
authors.lastname: Mnejja
authors.forename: B
authors.initials: B
authors.lastname: Hammami
authors.forename: I
authors.initials: I
authors.lastname: Achour
authors.forename: A
authors.initials: A
authors.lastname: Chakroun
authors.forename: I
authors.initials: I
authors.lastname: Charfeddine
authors.forename: M
authors.initials: M
authors.lastname: Frikha
authors.forename: J
authors.initials: J
authors.lastname: Daoud
authors.forename: A
authors.initials: A
authors.lastname: Ghorbel
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D004172:Diplopia / Q000209:etiology; D004724:Endoscopy; D005005:Ethmoid Sinus / Q000528:radiation effects*; D005260:Female; D005626:Frontal Sinus / Q000528:radiation effects*; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009078:Mucocele / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D015508:Nasal Obstruction / Q000209:etiology; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013101:Sphenoid Sinus / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed