title: Mid-ventricular obstructive hypertrophic cardiomyopathy during pregnancy complicated by preeclampsia and acute myocardial infarction: a case report.
abstract: Hypertrophic cardiomyopathy (HCM) with mid-ventricular obstruction (MVO) is a rare condition occurring in 1% of HCM patients. It is characterized by asymmetric left ventricular hypertrophy with MVO and elevated intraventricular pressure gradients. Myocardial infarction has been associated with mid-ventricular obstructive HCM. Briefly, this case presents an unusual clinical scenario where a young pregnant woman complicated by preeclampsia presents with myocardial injury and hemodynamic compromise related to undiagnosed HCM with MVO illustrating hemodynamic challenges created by pregnancy and surgery.
authors.affiliation: Heart Failure and Cardiac Transplant Fellow Texas Heart Institute, Baylor College of Medicine Houston, TX, USA.
authors.forename: Anand
authors.initials: A
authors.lastname: Singla
authors.forename: Steven E
authors.initials: SE
authors.lastname: Lipshultz
authors.forename: Stacy
authors.initials: S
authors.lastname: Fisher
mesh_terms: D000328:Adult; D024722:Cardiac Myosins / Q000235:genetics; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D002317:Cardiovascular Agents / Q000627:therapeutic use; D017023:Coronary Angiography; D004359:Drug Therapy, Combination; D015150:Echocardiography, Doppler; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008279:Magnetic Resonance Imaging; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D018995:Myosin Heavy Chains / Q000235:genetics; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D015635:Radionuclide Ventriculography; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; C501641:MYH7 protein, human; D024722:Cardiac Myosins; D018995:Myosin Heavy Chains