title: Double peak and prolonged absorption after large acetaminophen extended release and diphenhydramine ingestion.
abstract: Acetaminophen and acetaminophen combination products are the most frequent medications involved in intentional and unintentional poisonings. The 2008 National Poison Data System compiled by the American Association of Poison Control Centers documented 98,578 acetaminophen-related poisonings, which includes 91 fatalities. Very few case reports of ingestions of acetaminophen extended release with anticholinergics are reported in the literature.
authors.affiliation: Illinois Poison Center, Chicago, IL 60606, USA.
authors.forename: Tony
authors.initials: T
authors.lastname: Burda
authors.forename: Todd
authors.initials: T
authors.lastname: Sigg
mesh_terms: D000082:Acetaminophen / Q000493:pharmacokinetics / Q000506:poisoning*; D000328:Adult; D003692:Delayed-Action Preparations / Q000493:pharmacokinetics / Q000506:poisoning*; D004155:Diphenhydramine / Q000493:pharmacokinetics / Q000506:poisoning*; D062787:Drug Overdose / Q000453:epidemiology*; D005260:Female; D006801:Humans; D011039:Poison Control Centers / Q000706:statistics & numerical data; D013406:Suicide, Attempted; D014481:United States / Q000453:epidemiology
chemical_list: D003692:Delayed-Action Preparations; D000082:Acetaminophen; D004155:Diphenhydramine