title: Ankylosing spondylitis presented as unilateral optic neuritis in a young woman.
abstract: OBJECTIVE
  To report a case of ankylosing spondylitis that initially presented as unilateral optic neuritis.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Clinical findings and treatment are presented. A 31-year-old woman presented with unilateral optic neuritis in her right eye. Her symptom improved following pulse steroid therapy. Unfortunately, she developed severe pain and weakness in her bilateral knee and ankle joints during follow-up. Further investigation revealed a positive finding of HLA-B27 and bilateral sacroiliitis. Ankylosing spondylitis was confirmed and was treated with Salazine and Mobic.
  
  
  CONCLUSIONS
  Optic neuritis is rarely the first symptom of AS. Careful surveying and prompt treatment is necessary.
authors.affiliation: Department of Ophthalmology, Tri-Service General Hospital, Taipei, Taiwan.
authors.forename: Yen-Shou
authors.initials: YS
authors.lastname: Chou
authors.forename: Da-Wen
authors.initials: DW
authors.lastname: Lu
authors.forename: Jian-Tong
authors.initials: JT
authors.lastname: Chen
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018771:Arthralgia / Q000139:chemically induced; D055253:Color Vision; D004359:Drug Therapy, Combination; D005260:Female; D005654:Fundus Oculi; D015796:HLA-B27 Antigen / Q000097:blood; D006801:Humans; D000077239:Meloxicam; D009902:Optic Neuritis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D020551:Pulse Therapy, Drug; D011877:Radionuclide Imaging; D058566:Sacroiliitis / Q000000981:diagnostic imaging / Q000235:genetics; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D013256:Steroids / Q000008:administration & dosage / Q000009:adverse effects; D012460:Sulfasalazine / Q000627:therapeutic use; D013843:Thiazines / Q000627:therapeutic use; D013844:Thiazoles / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D015796:HLA-B27 Antigen; D013256:Steroids; D013843:Thiazines; D013844:Thiazoles; D012460:Sulfasalazine; D000077239:Meloxicam