title: Predictors of surgical and hearing long-term results for inlay cartilage tympanoplasty.
abstract: OBJECTIVE
  To determine the prognostic factors that affect surgical and audiologic outcomes in inlay tympanoplasty after long-term follow-up.
  
  
  METHODS
  Case series study.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  Sixty-two patients who underwent 71 procedures were enrolled in the study. Patient ages ranged from 31 to 87 years (mean [SD] age, 61.2 [12.9] years). Mean (SD) follow-up was 635.7 (284.7) days. The inclusion criteria were (1) inlay cartilage tympanoplasty performed using local anesthesia via a transcanal route, (2) chronic otitis media with stable perforation, and (3) dry ear without middle ear disease.
  
  
  METHODS
  The success rate and hearing change at the last follow-up visit.
  
  
  RESULTS
  The overall success rate was 87.3% at the last visit. Using multivariate analysis, sex, age, size of perforation, side of perforation, and the presence of diabetes mellitus and external auditory canal otomycosis did not affect the success. Smoking was the only independent factor for the prognosis of surgical outcome (odds ratio [OR], 8.16; 95% confidence interval [CI], 1.74-36.89; P < .006). On the other hand, age (OR, 6.62; 95% CI, 1.13-38.47; P = .03) and perforation size (OR, 0.11; 95% CI, 0.10-0.79; P = .03) were independent factors for the prognosis of audiologic outcomes.
  
  
  CONCLUSIONS
  The frequency of failure was significantly higher for smokers than for nonsmokers. To quit smoking is highly recommended preoperatively for individuals scheduled for chronic otitis media inlay tympanoplasty intervention. Younger patients and those with larger perforations (>50%) were more likely to benefit from this operation.
authors.affiliation: Department of Otolaryngology, Chang Gung Memorial Hospital at Chiayi, Taiwan.
authors.forename: Yi-Chiao
authors.initials: YC
authors.lastname: Lin
authors.forename: Wen-Hung
authors.initials: WH
authors.lastname: Wang
authors.forename: Hsu-Huei
authors.initials: HH
authors.lastname: Weng
authors.forename: Yen-Chun
authors.initials: YC
authors.lastname: Lin
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D002356:Cartilage / Q000637:transplantation*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000150:complications; D038781:Otoscopy; D011379:Prognosis; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D017211:Treatment Failure; D016896:Treatment Outcome; D018058:Tympanic Membrane Perforation / Q000601:surgery*; D014433:Tympanoplasty / Q000379:methods*