title: [Functional Assessment of Cancer Therapy Questionnaire for Breast Cancer (FACT-B+4). Spanish version validation].
abstract: OBJECTIVE
  To evaluate the acceptability, reliability, validity, and sensitivity to change of the Spanish version of the FACT-B+4 questionnaire, designed to assess the health related quality of life (HRQL) in breast cancer.
  
  
  METHODS
  Prospective study with 2 samples: patients with incident breast cancer (n=104) evaluated before and after surgery; and patients with chronic lymphedema of the upper extremity (n=30), evaluated twice in 7days. HRQL was assessed using the generic instrument SF-36 and the specific one FACT-B+4.
  
  
  RESULTS
  Reliability coefficients were ≥ 0.7 for most scores. The Physical wellbeing, Breast Cancer, Arm and TOI scores discriminated between patients with and without chemotherapy (p<0.05), while the Arm scale discriminated between patients with and without axillary surgery (p<0.001). In the worsening sub-sample, the FACT-B+4 detected changes in Physical, Emotional and Functional Wellbeing, and TOI scores.
  
  
  CONCLUSIONS
  The metric characteristics of the Spanish version of the FACT-B+4 are similar to the original questionnaire and support its equivalence, documenting its suitability for use in our country or in international studies.
authors.affiliation: Servei de Medicina Física i Rehabilitació, Hospital Mar-Esperança, Parc de Salut Mar, Barcelona, Spain. rbelmonte@parcdesalutmar.cat
authors.forename: Roser
authors.initials: R
authors.lastname: Belmonte Martínez
authors.forename: Olatz
authors.initials: O
authors.lastname: Garin Boronat
authors.forename: Marcel
authors.initials: M
authors.lastname: Segura Badía
authors.forename: Javier
authors.initials: J
authors.lastname: Sanz Latiesas
authors.forename: Ester
authors.initials: E
authors.lastname: Marco Navarro
authors.forename: Montserrat
authors.initials: M
authors.lastname: Ferrer Fores
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000523:psychology* / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects; D008209:Lymphedema / Q000209:etiology / Q000523:psychology; D008408:Mastectomy; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013030:Spain; D011795:Surveys and Questionnaires