title: Synthetic studies towards marmycins A and B: development of the vinylogous aldol-aza-Michael domino reaction.
abstract: The vinylogous aldol-aza-Michael domino reaction between 2-aminobenzaldehydes and prenal was developed to build up the core of natural products marmycin A and B without the need of protective groups.
authors.affiliation: Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bourcet
authors.forename: Manuel C
authors.initials: MC
authors.lastname: Bröhmer
authors.forename: Martin
authors.initials: M
authors.lastname: Nieger
authors.forename: Stefan
authors.initials: S
authors.lastname: Bräse
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000880:Anthraquinones / Q000138:chemical synthesis*; D001372:Aza Compounds / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D000447:Aldehydes; D000880:Anthraquinones; D001372:Aza Compounds; D014753:Vinyl Compounds; C524224:marmycin A; C524225:marmycin B; C116609:3-hydroxybutanal