title: Urine screening for Chlamydia trachomatis during pregnancy.
abstract: OBJECTIVE
  To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution.
  
  
  METHODS
  A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay.
  
  
  RESULTS
  A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]).
  
  
  CONCLUSIONS
  Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.
  
  
  METHODS
  II.
authors.affiliation: From the Department of Obstetrics and Gynecology, the University of Texas Southwestern Medical Center, Dallas, Texas.
authors.forename: Scott W
authors.initials: SW
authors.lastname: Roberts
authors.forename: Jeanne S
authors.initials: JS
authors.lastname: Sheffield
authors.forename: Don D
authors.initials: DD
authors.lastname: McIntire
authors.forename: James M
authors.initials: JM
authors.lastname: Alexander
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology / Q000652:urine*; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D011295:Prenatal Care / Q000379:methods; D011296:Prenatal Diagnosis / Q000379:methods*; D015995:Prevalence; D018570:Risk Assessment; D016482:Urinalysis / Q000379:methods; D014626:Vaginal Smears / Q000379:methods; D055815:Young Adult