title: Application of a metathesis reaction in the synthesis of sterically congested medium-sized rings. A direct ring closing versus a double bond migration-ring closing process.
abstract: An efficient double bond migration-ring closing metathesis reaction leading to cycloheptene derivatives is observed when specific sterically congested 1,9-dienes are treated with the Grubbs' imidazolidene ruthenium catalyst. The simultaneous use of the Grubbs' catalyst and RuClH(CO)(PPh(3))(3) facilitates the tandem bond migration-metathesis process. RuClH(CO)(PPh(3))(3) alone is capable of triggering an unactivated double bond migration that may have preparative applications.
authors.affiliation: Institute of Organic Chemistry of the Polish Academy of Sciences, Kasprzaka, 44/52, 01-224, Warsaw, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Michalak
authors.forename: Jerzy
authors.initials: J
authors.lastname: Wicha
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003517:Cyclopentanes