title: [Progress in researches on 46, XY disorders of sexual development].
abstract: 46, XY disorders of sexual development (46, XY DSD) are a group of complicated clinical conditions, which involve medical care, society, ethics and many other aspects. As chronic diseases, they necessitate long-term or even lifelong physical and mental follow-up and treatment. Early diagnosis and reasonable treatment could not only achieve appropriate development of the secondary sexual characteristics, but also effectively prevent gonadal malignancy. In recent years, environment pollution and other factors are contributing to the increasing incidence of 46, XY DSD all over the world. A deeper clinical insight into these disorders helps their earlier diagnosis and maximum improvement of prognosis. The etiology, new classification and treatment of 46, XY DSD are reviewed in this article.
authors.affiliation: Department of Pediatric Surgery, The Second Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Shou-xing
authors.initials: SX
authors.lastname: Duan
authors.forename: Jian-hong
authors.initials: JH
authors.lastname: Li
authors.forename: Xue-wu
authors.initials: XW
authors.lastname: Jiang
mesh_terms: D058490:Disorder of Sex Development, 46,XY / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male