title: [Strengthening of laboratories is a new component in the global strategy for tuberculosis control].
abstract: Although old techniques remain important, new techniques offer new possibilities. Mutations conferring resistance to rifampin and isoniazid can be detected in primary specimens from infectious pulmonary cases. Infections can be detected with interferon-gamma release assays, and chains of transmission can be detected by mycobacteria interspersed repetitive units. Centralized diagnostics makes it possible to apply results of routine analyses in national and international surveillance.
authors.affiliation: Mykobakteriologisk Laboratorium, Statens Serum Institut, Artillerivej 5, 2300 København S, Denmark. vot@ssi.dk
authors.forename: Vibeke Østergaard
authors.initials: VØ
authors.lastname: Thomsen
authors.forename: Didi
authors.initials: D
authors.lastname: Bang
authors.forename: Zaza
authors.initials: Z
authors.lastname: Kamper-Jørgensen
authors.forename: Julie
authors.initials: J
authors.lastname: Prahl
authors.forename: Erik Michael
authors.initials: EM
authors.lastname: Rasmussen
authors.forename: Dorte Bek
authors.initials: DB
authors.lastname: Folkvardsen
authors.forename: Niels
authors.initials: N
authors.lastname: Frimodt-Møller
mesh_terms: D015373:Bacterial Typing Techniques / Q000379:methods / Q000592:standards*; D003140:Communicable Disease Control / Q000379:methods / Q000592:standards*; D006801:Humans; D007371:Interferon-gamma / Q000378:metabolism; D007753:Laboratories / Q000592:standards*; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences; D014376:Tuberculosis / Q000175:diagnosis / Q000517:prevention & control*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis / Q000517:prevention & control; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000517:prevention & control; D014944:World Health Organization
chemical_list: D007371:Interferon-gamma