title: Synthesis and anti-microbial activity of hydroxylammonium ionic liquids.
abstract: Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid-base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens.
authors.affiliation: Chemical Engineering Department, Universiti Teknologi PETRONAS, 31750, Bandar Seri Iskandar, Tronoh, Perak, Malaysia.
authors.forename: M
authors.initials: M
authors.lastname: Ismail Hossain
authors.forename: Mohanad
authors.initials: M
authors.lastname: El-Harbawi
authors.forename: Yousr Abdulhadi
authors.initials: YA
authors.lastname: Noaman
authors.forename: Mohd Azmi B
authors.initials: MA
authors.lastname: Bustam
authors.forename: Noorjahan Banu Mohamed
authors.initials: NB
authors.lastname: Alitheen
authors.forename: Nor Azrin
authors.initials: NA
authors.lastname: Affandi
authors.forename: Glenn
authors.initials: G
authors.lastname: Hefter
authors.forename: Chun-Yang
authors.initials: CY
authors.lastname: Yin
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000633:toxicity*; D004202:Disinfectants / Q000138:chemical synthesis / Q000633:toxicity; D019811:Hydroxylamine / Q000138:chemical synthesis / Q000633:toxicity*; D052578:Ionic Liquids / Q000138:chemical synthesis / Q000633:toxicity*; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D004202:Disinfectants; D052578:Ionic Liquids; D019811:Hydroxylamine