title: Antibacterial activity of natural spices on multiple drug resistant Escherichia coli isolated from drinking water, Bangladesh.
abstract: BACKGROUND
  Spices traditionally have been used as coloring agents, flavoring agents, preservatives, food additives and medicine in Bangladesh. The present work aimed to find out the antimicrobial activity of natural spices on multi-drug resistant Escherichia coli isolates.
  
  
  METHODS
  Anti-bacterial potentials of six crude plant extracts (Allium sativum, Zingiber officinale, Allium cepa, Coriandrum sativum, Piper nigrum and Citrus aurantifolia) were tested against five Escherichia coli isolated from potable water sources at kushtia, Bangladesh.
  
  
  RESULTS
  All the bacterial isolates were susceptible to undiluted lime-juice. None of them were found to be susceptible against the aqueous extracts of garlic, onion, coriander, pepper and ginger alone. However, all the isolates were susceptible when subjected to 1:1:1 aqueous extract of lime, garlic and ginger. The highest inhibition zone was observed with lime (11 mm).
  
  
  CONCLUSIONS
  Natural spices might have anti-bacterial activity against enteric pathogens and could be used for prevention of diarrheal diseases. Further evaluation is necessary.
authors.affiliation: Department of Biotechnology and Genetic Engineering, Islamic University, Kushtia, Bangladesh
authors.forename: Shahedur
authors.initials: S
authors.lastname: Rahman
authors.forename: Anowar Khasru
authors.initials: AK
authors.lastname: Parvez
authors.forename: Rezuanul
authors.initials: R
authors.lastname: Islam
authors.forename: Mahboob Hossain
authors.initials: MH
authors.lastname: Khan
mesh_terms: D000490:Allium / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D032082:Citrus aurantiifolia / Q000737:chemistry; D028526:Coriandrum / Q000737:chemistry; D018432:Drug Resistance, Multiple; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification; D020939:Zingiber officinale / Q000737:chemistry; D029222:Piper nigrum / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology*; D017365:Spices / Q000032:analysis*; D014871:Water Microbiology; D014881:Water Supply / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts