title: Glucosamine-based primary amines as organocatalysts for the asymmetric aldol reaction.
abstract: Glucosamine derivatives have been synthesized starting from commercially available N-acetyl-D-glucosamine/glucosamine hydrochloride and have been employed successfully as efficient organocatalysts for the direct asymmetric aldol reaction between cyclohexanone and aryl aldehydes having diversified substituents. Furthermore, the anomeric effect of various groups present at the anomeric position on the catalytic activity of these organocatalysts was also studied.
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Roorkee 247 667, Uttarakhand, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Agarwal
authors.forename: Rama Krishna
authors.initials: RK
authors.lastname: Peddinti
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D005944:Glucosamine / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000588:Amines; D007659:Ketones; D005944:Glucosamine