title: Synthesis of sterically congested 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, N,N-dicyclohexylcarbodiimide and (N-isocyanimino)triphenylphosphorane.
abstract: Reactions of (N-isocyanimino)triphenylphosphorane with N,N-dicyclohexylcarbodiimide in the presence of aromatic (or heteroaromatic) carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions, and no side reactions were observed.
authors.affiliation: Chemistry Department, Zanjan University, PO Box 45195-313 Zanjan, Iran.
authors.forename: Fatemeh Zeinali
authors.initials: FZ
authors.lastname: Nasrabadi
authors.forename: Ali
authors.initials: A
authors.lastname: Ramazani
authors.forename: Yavar
authors.initials: Y
authors.lastname: Ahmadi
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D004024:Dicyclohexylcarbodiimide / Q000737:chemistry*; D015394:Molecular Structure; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D010753:Phosphoranes / Q000737:chemistry*
chemical_list: C569800:(N-isocyanimino)triphenylphosphorane; D002264:Carboxylic Acids; D010069:Oxadiazoles; D010753:Phosphoranes; D004024:Dicyclohexylcarbodiimide