title: Multiple hepatocellular adenomas in a patient with glycogen storage disease type I: various enhancement patterns in MRI with Gd-EOB-DTPA.
abstract: The patient is a 20-year-old man with glycogen storage disease type I (GSD-type I). In his teens, multiple focal hepatic masses were detected on abdominal ultrasonography (US), which were diagnosed as multiple hepatocellular adenomas from the imaging. During follow-up, these masses had shown intermittent growth in size. In the evaluation of Gd-EOB-DTPA (gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid) MR imaging, these masses showed various signal intensities from hypo- to hyperintense during the hepatocyte-specific phase. Intermittent growth and elevation of serum PIVKA-II levels indicate the potential for malignant transformation, so the patient underwent partial hepatectomy. The resected masses were all consistent with benign hepatocellular adenomas histopathologically.
authors.affiliation: Department of Radiology, Nagasaki University Hospital, Nagasaki, Japan. acmodel58319@yahoo.co.jp
authors.forename: Ayami
authors.initials: A
authors.lastname: Sakamoto
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Sakamoto
authors.forename: Ichiro
authors.initials: I
authors.lastname: Isomoto
authors.forename: Susumu
authors.initials: S
authors.lastname: Eguchi
authors.forename: Mitsuhisa
authors.initials: M
authors.lastname: Takatsuki
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanematsu
authors.forename: Kuniko
authors.initials: K
authors.lastname: Abe
authors.forename: Tomayoshi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Masataka
authors.initials: M
authors.lastname: Uetani
mesh_terms: D018248:Adenoma, Liver Cell / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D003287:Contrast Media; D019786:Gadolinium DTPA; D005953:Glycogen Storage Disease Type I / Q000150:complications*; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D055815:Young Adult
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA