title: Keloids can be forced into remission with surgical excision and radiation, followed by adjuvant therapy.
abstract: We have treated keloids using a combination of surgical excision and postoperative irradiation. The objective of this study was to evaluate the results of our treatment over 12 years. From 1995 until 2006, we treated keloids using the aforementioned treatment. If we identified a sign of recurrence during the follow-up period, we started an intralesional injection of triamcinolone acetonide immediately. We selected 91 keloids for which we had more than 2 years of follow-up data for this study and assessed the results according to our original scale (Kyoto scar scale) based on objective and subjective symptoms. In all, 51 keloids (56.0%) were cured completely by a combination of surgical excision and postoperative irradiation without additional treatment, and finally 81 keloids (89.0%) showed good results with additional treatment. Keloids are a controllable condition when treated with combination therapy, involving surgical excision with postoperative irradiation and early conservative treatment after the detection of recurrence.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan. satokoy@kuhp.kyoto-u.ac.jp
authors.forename: Satoko
authors.initials: S
authors.lastname: Yamawaki
authors.forename: Motoko
authors.initials: M
authors.lastname: Naitoh
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ishiko
authors.forename: Gan
authors.initials: G
authors.lastname: Muneuchi
authors.forename: Shigehiko
authors.initials: S
authors.lastname: Suzuki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007627:Keloid / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction; D016896:Treatment Outcome; D014221:Triamcinolone / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000893:Anti-Inflammatory Agents; D014221:Triamcinolone