title: [Therapeutic effect of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on type 2 diabetes mellitus in non-obese patients].
abstract: OBJECTIVE
  To evaluate the therapeutic effect of Roux-en-Y anastomosis following subtotal gastrectomy on type 2 diabetes mellitus (T2DM) in non-obese patients.
  
  
  METHODS
  We performed a retrospective analysis of 16 non-obese patients with T2DM undergoing Roux-en-Y anastomosis following subtotal gastrectomy for stomach cancer and upper gastrointestinal tract ulcer.
  
  
  RESULTS
  All the patients were followed up for 6 months after the surgery. Roux-en-Y gastrojejunostomy significantly lowered the levels of fasting plasma glucose (FPG), 2 h postprandial plasma glucose (2hPG), and glycated hemoglobin (HbA1c)(P<0.05). Of these patients, 8 (50%) achieved adequate glycemic control without antidiabetic medication and 5 (31.25%) showed obvious improvement. The total effectiveness rate of the surgery was 81.25%.
  
  
  CONCLUSIONS
  Roux-en-Y gastrectomy can effectively ameliorate the diabetic symptoms and might serve as a new treatment option for T2DM in non-obese patients.
authors.affiliation: Department of General Surgery, Third Xiangya Hospital of Central South University, Changsha 410013, China. fccc.1234@yahoo.cm.cn
authors.forename: Chao
authors.initials: C
authors.lastname: FENG
authors.forename: Ruo-quan
authors.initials: RQ
authors.lastname: YAO
authors.forename: Fei-zhou
authors.initials: FZ
authors.lastname: HUANG
authors.forename: Wan-pin
authors.initials: WP
authors.lastname: NIE
authors.forename: Xun-yang
authors.initials: XY
authors.lastname: LIU
mesh_terms: D000328:Adult; D000713:Anastomosis, Roux-en-Y; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity; D011184:Postoperative Period; D012189:Retrospective Studies; D016896:Treatment Outcome