title: Parenchymal leiomyoma of the breast: a case report with special reference to magnetic resonance imaging findings and an update review of literature.
abstract: Parenchymal leiomyomas of the breast are extremely rare, with only 25 cases reported in the literature. We report the 26th case of parenchymal leiomyoma of the breast in a 63-year-old woman who presented to us with a right breast tumor detected on her screening mammography. This tumor was evaluated by mammography, ultrasonography, and MR imaging. To the best of our knowledge, this is the first case of a parenchymal leiomyoma of the breast examined by MR imaging. MR imaging revealed an oval mass with circumscribed margins that appeared as a high-intensity lesion in both T1 and T2. A dynamic MRI study showed a gradual increase pattern on the mass. Excisional biopsy revealed a growth pattern of interlacing fascicles of spindle cells without atypia or mitoses, consistent with parenchymal leiomyoma of the breast. Here we report a case of parenchymal leiomyoma of the breast, and describe the clinical, pathological, and immunohistochemical findings. In addition, we review the literature on parenchymal leiomyoma of the breast with regard to clinical characteristics and pathological features of this entity.
authors.affiliation: Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. shiminami-gi@umin.net
authors.forename: Shigeki
authors.initials: S
authors.lastname: Minami
authors.forename: Shigetoshi
authors.initials: S
authors.lastname: Matsuo
authors.forename: Takashi
authors.initials: T
authors.lastname: Azuma
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Uga
authors.forename: Tomayoshi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Susumu
authors.initials: S
authors.lastname: Eguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kanematsu
mesh_terms: D000328:Adult; D000368:Aged; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D016217:Ultrasonography, Mammary