title: Electrospun scaffolds for bone tissue engineering.
abstract: Tissue engineering aims to regenerate native tissues and will represent the alternative choice of standard surgery for different kind of tissue damages. The fundamental basis of tissue engineering is the appropriate selection of scaffolds and their morphological, mechanical, chemical, and biomimetic properties, closely related to cell lines that will be seeded therein. The aim of this review is to summarize and report the innovative scientific contributions published in the field of orthopedic tissue engineering, in particular about bone tissue engineering. We have focused our attention on the electrospinning technique, as a scaffold fabrication method. Electrospun materials are being evaluated as scaffolds for bone tissue engineering, and the results of all these studies clearly indicate that they represent suitable potential substrates for cell-based technologies.
authors.affiliation: Department of Orthopaedics and Trauma Surgery, University Campus Bio-Medico of Rome, Via Álvaro del Portillo, 200, 00128 Rome, Italy. a.dimartino@unicampus.it
authors.forename: Alberto
authors.initials: A
authors.lastname: Di Martino
authors.forename: Liliana
authors.initials: L
authors.lastname: Liverani
authors.forename: Alberto
authors.initials: A
authors.lastname: Rainer
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Salvatore
authors.forename: Marcella
authors.initials: M
authors.lastname: Trombetta
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Denaro
mesh_terms: D001842:Bone and Bones; D004563:Electrochemistry; D005109:Extracellular Matrix / Q000737:chemistry; D006801:Humans; D008422:Materials Testing; D009985:Orthopedics / Q000639:trends*; D023822:Tissue Engineering / Q000379:methods; D054457:Tissue Scaffolds / Q000737:chemistry*