title: One-pot synthesis of 2-imidazolines via the ring expansion of imidoyl chlorides with aziridines.
abstract: We herein report a simple and convenient one-pot synthesis of highly substituted 2-imidazolines in a regiocontrolled and stereospecific matter through the ring expansion reaction of an imidoyl chloride with an aziridine, analogous to the Heine reaction.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48823, United States.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Kuszpit
authors.forename: William D
authors.initials: WD
authors.lastname: Wulff
authors.forename: Jetze J
authors.initials: JJ
authors.lastname: Tepe
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D001688:Biological Products / Q000138:chemical synthesis*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry; D004987:Ethers / Q000737:chemistry; D048288:Imidazolines / Q000138:chemical synthesis*; D007094:Imides / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D001688:Biological Products; D002712:Chlorides; D004987:Ethers; D048288:Imidazolines; D007094:Imides; C033132:aziridine