title: Postvaricella purpura fulminans with no evidence of disseminated intravascular coagulation (DIC) or protein S deficiency.
abstract: The mechanism of postvaricella purpura fulminans is thought to be due to development of antiprotein S antibodies. These antibodies lead to an acquired transient severe protein S deficiency which results in disseminated intravascular coagulation and microvascular thrombosis. Here a patient presented with postvaricella purpura fulminans, where no clinical or laboratory evidence of disseminated intravascular coagulation could be found and there was no deficiency of protein S.
authors.affiliation: Department of Medicine, Gandhi Medical College and Hamidia Hospital, Bhopal 462001.
authors.forename: V K
authors.initials: VK
authors.lastname: Sharma
authors.forename: T N
authors.initials: TN
authors.lastname: Dubey
authors.forename: Lokendra
authors.initials: L
authors.lastname: Dave
authors.forename: Ashish
authors.initials: A
authors.lastname: Agarwal
mesh_terms: D000328:Adult; D002644:Chickenpox / Q000150:complications*; D005260:Female; D005734:Gangrene; D006801:Humans; D055665:Purpura Fulminans / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D014034:Toes