title: Impact of metabolic syndrome on clinical outcomes after drug-eluting stent implantation in patients with coronary artery disease.
abstract: Metabolic syndrome (MetS) is regarded as a risk factor for coronary artery disease (CAD). However, the influence of MetS on morbidity and mortality after drug-eluting stent (DES) implantation in Chinese patients with CAD remains unknown. We evaluated the impact of MetS on the clinical outcome of 1224 patients following DES implantation. After a mean follow-up of 35.4 months, patients with MetS had a significantly higher incidence of all-cause death and major adverse cardiovascular events (MACE) compared with patients without MetS (P < .001). Analyses of individual MetS components showed that dysglycemia at the time of DES implantation predicted increased all-cause mortality, while the presence of hypertension and dysglycemia predicted increased incidence of MACE.
authors.affiliation: Department of Cardiology, Anzhen Hospital/Capital Medical University, Chao Yang, Beijing, China. hubin80@126.com
authors.lastname: Bin Hu
authors.lastname: Yujie Zhou
authors.lastname: Yuyang Liu
authors.lastname: Dongmei Shi
authors.lastname: Yingxin Zhao
authors.lastname: Dean Jia
authors.lastname: Shiwei Yang
authors.lastname: Zhe Fang
authors.lastname: Bin Nie
mesh_terms: D003324:Coronary Artery Disease / Q000150:complications* / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D016896:Treatment Outcome