title: Primary cardiac angiosarcoma: in a patient with a dacron aortic prosthesis.
abstract: This is a report of a primary cardiac angiosarcoma in a woman who, several years earlier, had undergone repair of an aortic dissection with a Dacron graft prosthesis. Dacron prostheses have rarely been associated with neoplasia, and this, to our knowledge, is the first reported case of primary cardiac angiosarcoma in association with Dacron. Our patient presented with extensive metastases. If tumors are localized, they can be treated successfully with a combination of surgical resection, chemotherapy, and radiotherapy. Cardiac transplantation can also be beneficial, but the overall prognosis remains poor.
authors.affiliation: The Cardiac Center of Creighton University, Creighton University Medical Center, Omaha, Nebraska 68131, USA. nathan.almeida@cardiac.creighton.edu
authors.forename: Nathan J
authors.initials: NJ
authors.lastname: Almeida
authors.forename: Priscilla
authors.initials: P
authors.lastname: Hoang
authors.forename: Paul
authors.initials: P
authors.lastname: Biddle
authors.forename: Amy
authors.initials: A
authors.lastname: Arouni
authors.forename: Dennis
authors.initials: D
authors.lastname: Esterbrooks
mesh_terms: D000784:Aortic Dissection / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006394:Hemangiosarcoma / Q000209:etiology* / Q000556:secondary / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000009:adverse effects*; D011474:Prosthesis Design; D014057:Tomography, X-Ray Computed
chemical_list: D011093:Polyethylene Terephthalates