title: Thrombolytic therapy in the treatment of right-sided prosthetic valve thrombosis in adults with congenital heart disease.
abstract: Valve thrombosis is a potentially dangerous complication for right sided prosthetic valves in adults with congenital heart disease. Thrombolytic therapy is an important alternative to surgery and may be of benefit in patients with a history of multiple surgical interventions. We present two cases of successful thrombolytic therapy for right sided valve thrombosis in patients with congenital heart disease.
authors.affiliation: Divisions of Pediatric Cardiology Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Johnson
authors.forename: R Andrew
authors.initials: RA
authors.lastname: Rauh
authors.forename: Sabrina D
authors.initials: SD
authors.lastname: Phillips
authors.forename: Frank
authors.initials: F
authors.lastname: Cetta
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006330:Heart Defects, Congenital / Q000150:complications* / Q000601:surgery; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D006801:Humans; D008297:Male; D015641:Radiography, Interventional; D012086:Reoperation; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator