title: Folic acid-functionalized two-photon absorbing nanoparticles for targeted MCF-7 cancer cell imaging.
abstract: We report a facile strategy to synthesize folic acid-functionalized two-photon absorbing (TPA) nanoparticles with aggregation-induced emission for targeted cancer cell imaging using a two-photon fluorescence microscope.
authors.affiliation: Department of Chemical and Biomolecular Engineering, 4 Engineering Drive 4, National University of Singapore, Singapore, 117576, Singapore.
authors.forename: Kai
authors.initials: K
authors.lastname: Li
authors.forename: Yihua
authors.initials: Y
authors.lastname: Jiang
authors.forename: Dan
authors.initials: D
authors.lastname: Ding
authors.forename: Xinhai
authors.initials: X
authors.lastname: Zhang
authors.forename: Yutao
authors.initials: Y
authors.lastname: Liu
authors.forename: Jianli
authors.initials: J
authors.lastname: Hua
authors.forename: Si-Shen
authors.initials: SS
authors.lastname: Feng
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
mesh_terms: D000042:Absorption; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology*; D045744:Cell Line, Tumor; D005260:Female; D005492:Folic Acid / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D057054:Molecular Imaging / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D010714:Phosphatidylethanolamines / Q000737:chemistry; D017785:Photons; D011092:Polyethylene Glycols / Q000737:chemistry; D013499:Surface Properties
chemical_list: C519184:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000); D010714:Phosphatidylethanolamines; D011092:Polyethylene Glycols; D005492:Folic Acid