title: Comparison outcome of fresh and vitrified donor oocytes in an egg-sharing donation program.
abstract: OBJECTIVE
  To compare the survival, fertilization, early embryonic development, and clinical outcomes from fresh and vitrified cohort oocytes.
  
  
  METHODS
  Review of egg-sharing program, in which the eggs from one donor were shared by recipients of fresh and vitrified eggs.
  
  
  METHODS
  IVF center.
  
  
  METHODS
  77 women, comprising 36 patients receiving vitrified donor oocytes and 41 patients receiving fresh donor oocytes.
  
  
  METHODS
  Shared donor eggs vitrified by the Cryotop method warmed after vitrification, with microinjection of surviving metaphase 2 (MII) or fresh oocytes.
  
  
  METHODS
  Survival, fertilization, cleavage rate, pregnancy rate, and implantation.
  
  
  RESULTS
  Of the vitrified oocytes, 192 (91.4%) survived. There was no statistically significant difference in fertilization and cleavage rates, embryo quality, or clinical results obtained from vitrified compared with fresh oocytes. The outcomes of cycles using fresh oocytes were predictive of the cycle outcomes after warming of oocytes from the same cohort.
  
  
  CONCLUSIONS
  Oocyte donations using vitrified oocytes can provide the same quality of embryos, pregnancy, and implantation potential as fresh oocyte donations.
authors.affiliation: Pedieos IVF Center, Nicosia, Cyprus.
authors.forename: Krinos M
authors.initials: KM
authors.lastname: Trokoudes
authors.forename: Constantinos
authors.initials: C
authors.lastname: Pavlides
authors.forename: Xiao
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D015925:Cryopreservation; D046149:Embryo Culture Techniques; D010064:Embryo Implantation / Q000502:physiology; D047108:Embryonic Development / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D018587:Oocyte Donation / Q000379:methods*; D054315:Oocyte Retrieval / Q000379:methods*; D009865:Oocytes; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D016896:Treatment Outcome; D058989:Vitrification