title: Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan.
abstract: Multilocus sequence typing of Borrelia garinii isolates from humans and comparison with rodent and tick isolates were performed. Fifty-nine isolates were divided into two phylogenetic groups, and an association was detected between clinical and rodent isolates, suggesting that, in Japan, human-pathogenic B. garinii comes from rodents via ticks.
authors.affiliation: Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
authors.forename: Ai
authors.initials: A
authors.lastname: Takano
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakao
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Masuzawa
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takada
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yano
authors.forename: Fubito
authors.initials: F
authors.lastname: Ishiguro
authors.forename: Hiromi
authors.initials: H
authors.lastname: Fujita
authors.forename: Takuya
authors.initials: T
authors.lastname: Ito
authors.forename: Xiaohang
authors.initials: X
authors.lastname: Ma
authors.forename: Yozaburo
authors.initials: Y
authors.lastname: Oikawa
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Kawamori
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Kumagai
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Mikami
authors.forename: Nozomu
authors.initials: N
authors.lastname: Hanaoka
authors.forename: Shuji
authors.initials: S
authors.lastname: Ando
authors.forename: Naoko
authors.initials: N
authors.lastname: Honda
authors.forename: Kyle
authors.initials: K
authors.lastname: Taylor
authors.forename: Toshio
authors.initials: T
authors.lastname: Tsubota
authors.forename: Satoru
authors.initials: S
authors.lastname: Konnai
authors.forename: Haruo
authors.initials: H
authors.lastname: Watanabe
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohnishi
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kawabata
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D015748:Borrelia burgdorferi Group / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004197:Disease Reservoirs; D005838:Genotype; D006801:Humans; D007564:Japan; D008193:Lyme Disease / Q000382:microbiology*; D008969:Molecular Sequence Data; D058885:Multilocus Sequence Typing; D010802:Phylogeny; D012377:Rodentia / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D013987:Ticks / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial