title: Preparation of unsymmetrical distyryl BODIPY derivatives and effects of the styryl substituents on their in vitro photodynamic properties.
abstract: A series of unsymmetrical distyryl BODIPYs have been prepared which function as highly potent photosensitisers with in vitro IC(50) values as low as 15 nM. Their cellular uptake, subcellular localisation and photocytotoxicity depend greatly on the styryl substituents.
authors.affiliation: Department of Chemistry, The Chinese University of Hong Kong, Shatin, N. T., Hong Kong, China.
authors.forename: Hui
authors.initials: H
authors.lastname: He
authors.forename: Pui-Chi
authors.initials: PC
authors.lastname: Lo
authors.forename: Sin-Lui
authors.initials: SL
authors.lastname: Yeung
authors.forename: Wing-Ping
authors.initials: WP
authors.lastname: Fong
authors.forename: Dennis K P
authors.initials: DK
authors.lastname: Ng
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D017319:Photosensitizing Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013343:Styrenes / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D017319:Photosensitizing Agents; D013343:Styrenes