title: Utility of the national embryo morphology data collection by the Society for Assisted Reproductive Technologies (SART): correlation between day-3 morphology grade and live-birth outcome.
abstract: Analysis of the "grade" field in the first embryo morphology data collected under the classification system developed by Society for Assisted Reproductive Technology (SART) and reported to the SART Clinic Outcomes Reporting System (SART CORS) database showed that when two embryos of the same grade were transferred on day 3, the live-birth rate declined with decreasing grade (<35 years old: good = 50.4%; fair = 42.2%; poor = 22.0%; ≥ 35 years old: good = 35.1%; fair = 23.4%; poor = 20.0%). These findings provide the first evidence that collecting the "grade" field in the national morphology collection system is valid and can be developed into a standard for use by individual SART programs for quality assurance assessment and for improved embryo selection.
authors.affiliation: Department of Obstetrics and Gynecology, West Virginia University, Morgantown, West Virginia, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Vernon
authors.forename: Judy E
authors.initials: JE
authors.lastname: Stern
authors.forename: G David
authors.initials: GD
authors.lastname: Ball
authors.forename: David
authors.initials: D
authors.lastname: Wininger
authors.forename: Jacob
authors.initials: J
authors.lastname: Mayer
authors.forename: Catherine
authors.initials: C
authors.lastname: Racowsky
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D019992:Databases as Topic; D004624:Embryo Transfer / Q000009:adverse effects / Q000592:standards*; D004622:Embryo, Mammalian / Q000473:pathology*; D005260:Female; D006801:Humans; D050498:Live Birth; D008423:Maternal Age; D008853:Microscopy / Q000592:standards*; D011247:Pregnancy; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects / Q000592:standards*; D012955:Societies, Medical / Q000592:standards*; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States