title: Maternal and prenatal factors influencing the outcome of prostaglandin E2 induced labour.
abstract: In this retrospective cohort study involving 393 singleton pregnancies, we evaluated the maternal and prenatal factors influencing the use of and the outcome of prostaglandin E(2) (PGE(2)) induced labours. Only a nulliparous pregnancy was shown to be a significant predictor of the use of more than one dose of PGE(2) (odds ratio, OR 2.73, 95% confidence interval, CI 1.61-4.63). When the type of delivery was assessed, nulliparous status was significantly associated with a decreased chance of vaginal delivery (OR 0.12, 95% CI 0.045-0.32). Other variables that positively influence the chance of vaginal delivery include a mother's age being under 30 years (OR 2.63, 95% CI 1.51-4.58) and a single dose of PGE(2) (OR 2.86, 95% CI 1.21-6.79). Gestational age, fetal weight and maternal BMI have much less impact on PGE(2) use and chance of successful vaginal delivery than parity.
authors.affiliation: Department of Obstetrics and Gynaecology, Cumberland Infirmary, North Cumbria University Hospitals, UK.
authors.forename: F
authors.initials: F
authors.lastname: Memon
authors.forename: A
authors.initials: A
authors.lastname: Wijesiriwardana
authors.forename: L
authors.initials: L
authors.lastname: Jonker
mesh_terms: D000328:Adult; D015992:Body Mass Index; D020070:Cervical Ripening; D015331:Cohort Studies; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D020567:Fetal Weight; D005865:Gestational Age; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D008423:Maternal Age; D016017:Odds Ratio; D010298:Parity; D011247:Pregnancy; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D015232:Dinoprostone