title: Nanodomain stabilization dynamics in plasma membranes of biological cells.
abstract: We discover that a synergistically amplifying role of stabilizing membrane proteins and continuous lipid recycling can explain the physics governing the stability, polydispersity, and dynamics of lipid raft domains in plasma membranes of biological cells. We establish the conjecture using a generalized order parameter based on theoretical formalism, endorsed by detailed scaling arguments and domain mapping. Quantitative agreements with morphological distributions of raft complexes, as obtained from Förster resonance energy transfer based visualization, support the present theoretical conjecture.
authors.affiliation: Department of Biotechnology, Indian Institute of Technology, Kharagpur 721302, India.
authors.forename: Tamal
authors.initials: T
authors.lastname: Das
authors.forename: Tapas K
authors.initials: TK
authors.lastname: Maiti
authors.forename: Suman
authors.initials: S
authors.lastname: Chakraborty
mesh_terms: D002462:Cell Membrane / Q000737:chemistry* / Q000502:physiology*; D003198:Computer Simulation; D008565:Membrane Proteins / Q000737:chemistry* / Q000502:physiology*; D008954:Models, Biological; D008956:Models, Chemical
chemical_list: D008565:Membrane Proteins