title: [Intraoperative radiotherapy in multimodality treatment of locally advanced rectal carcinoma].
abstract: Multimodality treatment of locally advanced rectal cancer combines radical surgery, radiotherapy and chemotherapy. This method leads to improvement of local control and overall survival. However, some of the patients incur local failure of disease, which are localized predominantly in presacral region. The integration of intraoperative radiotherapy as part of a multimodal treatment approach helps to a further dose escalation without increasing toxicity, and reduces the likelihood of otherwise difficult curable local failure.
authors.affiliation: Oddelení radioterapie a onkologie, Komplexní onkologické centrum Nový Jicín. renata.soumarova@onkogickecentrum.cz
authors.forename: R
authors.initials: R
authors.lastname: Soumarová
authors.forename: M
authors.initials: M
authors.lastname: Skrovina
authors.forename: S
authors.initials: S
authors.lastname: Machala
authors.forename: L
authors.initials: L
authors.lastname: Adamcík
authors.forename: J
authors.initials: J
authors.lastname: Bartos
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D007432:Intraoperative Period; D020360:Neoadjuvant Therapy; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016879:Salvage Therapy