title: Methicillin-resistant Staphylococcus aureus USA300 clone as a cause of Lemierre's syndrome.
abstract: We describe a case of a young woman who had methicillin-resistant Staphylococcus aureus USA300 clone (MRSA-USA300)-associated Lemierre's syndrome and secondary necrotizing pneumonia and cerebral infarcts. We also review 11 cases of S. aureus-associated Lemierre's syndrome reported in the literature from 1965 to 2010. Recognition of S. aureus as an emergent cause of Lemierre's syndrome informs the initial empirical antibiotic choice for this life-threatening condition and may positively impact patient outcomes.
authors.affiliation: Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110-1093, USA.
authors.forename: Jake M
authors.initials: JM
authors.lastname: Chanin
authors.forename: Luis A
authors.initials: LA
authors.lastname: Marcos
authors.forename: Bithika M
authors.initials: BM
authors.lastname: Thompson
authors.forename: Roger D
authors.initials: RD
authors.lastname: Yusen
authors.forename: W Michael
authors.initials: WM
authors.lastname: Dunne
authors.forename: David K
authors.initials: DK
authors.lastname: Warren
authors.forename: Carlos A Q
authors.initials: CA
authors.lastname: Santos
mesh_terms: D015373:Bacterial Typing Techniques; D002544:Cerebral Infarction / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D005838:Genotype; D006801:Humans; D057831:Lemierre Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D058889:Molecular Typing; D011023:Pneumonia, Staphylococcal / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D013203:Staphylococcal Infections / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D055815:Young Adult