title: Application of emerging toxicity screens in drug discovery: challenges and implications.
authors.forename: Alan G E
authors.initials: AG
authors.lastname: Wilson
authors.forename: Xuemei
authors.initials: X
authors.lastname: Liu
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Kramer
mesh_terms: D017209:Apoptosis; D004249:DNA Damage; D004260:DNA Repair; D004353:Drug Evaluation, Preclinical; D004345:Drug Industry / Q000191:economics; D064420:Drug-Related Side Effects and Adverse Reactions; D004721:Endoplasmic Reticulum / Q000378:metabolism; D051638:Ether-A-Go-Go Potassium Channels / Q000378:metabolism; D057166:High-Throughput Screening Assays; D057093:Orphan Nuclear Receptors / Q000378:metabolism; D018384:Oxidative Stress; D004364:Pharmaceutical Preparations / Q000378:metabolism; D018675:Toxicity Tests / Q000191:economics / Q000379:methods
chemical_list: D051638:Ether-A-Go-Go Potassium Channels; D057093:Orphan Nuclear Receptors; D004364:Pharmaceutical Preparations