title: Indonesian propolis: chemical composition, biological activity and botanical origin.
abstract: From a biologically active extract of Indonesian propolis from East Java, 11 compounds were isolated and identified: four alk(en)ylresorcinols (obtained as an inseparable mixture) (1-4) were isolated for the first time from propolis, along with four prenylflavanones (6-9) and three cycloartane-type triterpenes (5, 10 and 11). The structures of the components were elucidated based on their spectral properties. All prenylflavanones demonstrated significant radical scavenging activity against diphenylpicrylhydrazyl radicals, and compound 6 showed significant antibacterial activity against Staphylococcus aureus. For the first time Macaranga tanarius L. and Mangifera indica L. are shown as plant sources of Indonesian propolis.
authors.affiliation: Institute of Organic Chemistry with the Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria. bobi_tru@orgchm.bas.bg
authors.forename: Boryana
authors.initials: B
authors.lastname: Trusheva
authors.forename: Milena
authors.initials: M
authors.lastname: Popova
authors.forename: Eko Budi
authors.initials: EB
authors.lastname: Koendhori
authors.forename: Iva
authors.initials: I
authors.lastname: Tsvetkova
authors.forename: Christo
authors.initials: C
authors.lastname: Naydenski
authors.forename: Vassya
authors.initials: V
authors.lastname: Bankova
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000302:isolation & purification*; D007214:Indonesia; D031022:Mangifera / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011429:Propolis / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D016166:Free Radical Scavengers; D011429:Propolis