title: TEQC: an R package for quality control in target capture experiments.
abstract: TEQC is an R/Bioconductor package for quality assessment of target enrichment experiments. Quality measures comprise specificity and sensitivity of the capture, enrichment, per-target read coverage and its relation to hybridization probe characteristics, coverage uniformity and reproducibility, and read duplicate analysis. Several diagnostic plots allow visual inspection of the data quality.
  
  
  METHODS
  TEQC is implemented in the R language (version >2.12.0) and is available as a Bioconductor package for Linux, Windows and MacOS from www.bioconductor.org.
authors.affiliation: Core Facilities, Centre for Genomic Regulation, UPF, Barcelona, Spain. manuela.hummel@crg.es
authors.forename: Manuela
authors.initials: M
authors.lastname: Hummel
authors.forename: Sarah
authors.initials: S
authors.lastname: Bonnin
authors.forename: Ernesto
authors.initials: E
authors.lastname: Lowy
authors.forename: Guglielmo
authors.initials: G
authors.lastname: Roma
mesh_terms: D019295:Computational Biology / Q000379:methods*; D015342:DNA Probes; D009693:Nucleic Acid Hybridization; D016133:Polymerase Chain Reaction; D011786:Quality Control; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
chemical_list: D015342:DNA Probes