title: Aptima Combo 2 testing detected additional cases of Neisseria gonorrhoeae infection in men and women in community settings.
abstract: Aptima Combo 2 (AC2) Neisseria gonorrhoeae testing of 81,405 patients who were tested by culture and 14,666 who were AC2 tested for Chlamydia trachomatis detected 142 extra infections and confirmed 106 culture-positive samples (the positivity rate increased from 0.13 in testing by culture to 0.26 in testing by AC2). Retrievable AC2 positive samples were confirmed (98.5%) by an alternate AGC test.
authors.affiliation: Gamma Dynacare Medical Laboratories, Brampton, Ontario, Canada.
authors.forename: Julius
authors.initials: J
authors.lastname: Kapala
authors.forename: Kathy
authors.initials: K
authors.lastname: Biers
authors.forename: Michael
authors.initials: M
authors.lastname: Cox
authors.forename: Margaret
authors.initials: M
authors.lastname: Kamionka
authors.forename: Jeff
authors.initials: J
authors.lastname: Sumner
authors.forename: Ramandeep
authors.initials: R
authors.lastname: Toor
authors.forename: Jodi
authors.initials: J
authors.lastname: Gilchrist
authors.forename: Dan
authors.initials: D
authors.lastname: Jang
authors.forename: Marek
authors.initials: M
authors.lastname: Smieja
authors.forename: Max
authors.initials: M
authors.lastname: Chernesky
mesh_terms: D002690:Chlamydia Infections / Q000175:diagnosis; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis*; D006801:Humans; D008297:Male; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods; D012680:Sensitivity and Specificity