title: Low cytotoxicity porous Nd(2)(SiO(4))(3) nanoparticles with near infrared excitation and emission.
abstract: Porous Nd(2)(SiO(4))(3) nanoparticles were successfully synthesized by a controlled route. This kind of silicate nanoparticle could be excited by near-infrared (NIR) radiation (808 nm) and triggered a NIR emission (1066 nm) at room temperature. By monitoring the 1066 nm emission, the long-lived luminescent lifetime was determined to be 19.5 µs. These NIR nanoparticles with appropriate diameters (<100 nm) were suitable for cell assays. MTT assays showed that the cytotoxicity of the porous Nd(2)(SiO(4))(3) nanoparticles was very low. Therefore, these porous silicate nanoparticles are potential biosafe high-performance NIR biolabeling materials.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, People's Republic of China. xhzhang@xmu.edu.cn
authors.forename: Xian-Hua
authors.initials: XH
authors.lastname: Zhang
authors.forename: Dequan
authors.initials: D
authors.lastname: Zeng
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Haomiao
authors.initials: H
authors.lastname: Zhu
authors.forename: Guang-Hui
authors.initials: GH
authors.lastname: Jin
authors.forename: Zhaoxiong
authors.initials: Z
authors.lastname: Xie
authors.forename: Xueyuan
authors.initials: X
authors.lastname: Chen
authors.forename: Junyong
authors.initials: J
authors.lastname: Kang
authors.forename: Lansun
authors.initials: L
authors.lastname: Zheng
mesh_terms: D002470:Cell Survival; D056945:Hep G2 Cells; D006801:Humans; D007259:Infrared Rays; D049449:Luminescence; D049408:Luminescent Agents / Q000737:chemistry / Q000378:metabolism*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009354:Neodymium; D016062:Porosity; D017640:Silicates / Q000737:chemistry / Q000378:metabolism*; D019265:Spectroscopy, Near-Infrared / Q000379:methods
chemical_list: D049408:Luminescent Agents; D017640:Silicates; D009354:Neodymium