title: Pigmented villonodular synovitis of joints.
abstract: OBJECTIVE
  The objective of this study is to present two series of cases of pigmented villonodular disease of joints (PVNS) treated at different periods. The 215 cases from our hospital are current (1972-2009) and those 62 from the Jaffe collection from 1920 to 1968.
  
  
  METHODS
  By use of our computerized tumor data system we were able to define age, gender, site, treatment, complications, and outcome. Examination of the material from the Jaffe collection included all of the above primary data but none on treatment and outcome.
  
  
  RESULTS
  The data for the two systems studied were remarkably similar. The average ages were in mid years and the disorder was more frequent in females. The largest numbers of cases for both series were in the knee and foot and less commonly in hip, shoulder, and hand. The treatments were mostly surgical excision with the exception of the hip which required total hip replacement. The results show only a small number of recurrences, no metastatic disease and no deaths.
  
  
  CONCLUSIONS
  Pigmented villonodular disease of joints is a rare entity, mostly occurring in the knee and foot. The principal treatment is surgical excision which is most often successful in these sites but leads to problems at other locations, especially the hip.
authors.affiliation: Department of Orthopaedics, Massachusetts General Hospital, Boston, Massachusetts, USA. hmankin@partners.org
authors.forename: Henry
authors.initials: H
authors.lastname: Mankin
authors.forename: Carol
authors.initials: C
authors.lastname: Trahan
authors.forename: Francis
authors.initials: F
authors.lastname: Hornicek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006621:Hip Joint / Q000473:pathology / Q000601:surgery; D006801:Humans; D007592:Joint Diseases / Q000473:pathology* / Q000601:surgery; D007719:Knee Joint / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013586:Synovitis, Pigmented Villonodular / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult