title: Predictive preoperatory variables of the prostate tumor volume.
abstract: Prostate cancer (PCa) is the second most frequent malignant tumor in men worldwide and the most common form of cancer in men over 50-year-old. The adequate preoperative estimation of tumor volume in order to identify small tumors that lack a short-term aggressive behavior and do not necessitate a forthwith-radical prostatectomy (RP) is the subject of various recent studies and numerous debates. In this study, that included 128 cases, we attempted to evaluate some of the common preoperative variables (patient's age, total prostate volume determined on ultrasound examination, serum PSA, the number of positive biopsies and tumor size, the percentage of tumor length and the Gleason score) that could predict the tumor volume on the final RP. Based on these correlations, we develop a scoring system that combines only the Gleason score, the number of positive biopsies and the percentage of tumor length and that has been statistically proved to be correlated and predictive for the tumor volume. Our study brings additional and practical information about a true and effective prospective evaluation of the volume of the PCa.
authors.affiliation: Department of Histology, University of Medicine and Pharmacy of Targu Mures, Romania. andradaloghin@yahoo.com
authors.forename: Andrada
authors.initials: A
authors.lastname: Loghin
authors.forename: O
authors.initials: O
authors.lastname: Preda
authors.forename: V
authors.initials: V
authors.lastname: Bacârea
authors.forename: C
authors.initials: C
authors.lastname: Moldovan
authors.forename: D
authors.initials: D
authors.lastname: Porav-Hodade
authors.forename: Alis
authors.initials: A
authors.lastname: Dema
authors.forename: Nicole
authors.initials: N
authors.lastname: Berger
authors.forename: Angela
authors.initials: A
authors.lastname: Borda
mesh_terms: D001706:Biopsy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011379:Prognosis; D011467:Prostate / Q000473:pathology / Q000601:surgery; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D047368:Tumor Burden