title: Advances in endovascular treatment of critical limb ischemia.
abstract: Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease. In the absence of timely revascularization, CLI carries high risk of mortality and amputation. Over the past decade, endovascular revascularization has rapidly become the preferred primary treatment strategy for CLI, especially for the treatment of below-the-knee disease. Advances in percutaneous devices and techniques have expanded the spectrum of patients with CLI who are deemed candidates for revascularization. This review will focus on advances in endovascular options for the treatment of CLI, in particular for below-the-knee disease.
authors.affiliation: Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital & Institute of Vascular Medicine, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Yan
authors.forename: Darragh
authors.initials: D
authors.lastname: Moran
authors.forename: Brian G
authors.initials: BG
authors.lastname: Hynes
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Kiernan
authors.forename: Cheuk-Man
authors.initials: CM
authors.lastname: Yu
mesh_terms: D000818:Animals; D006801:Humans; D007511:Ischemia / Q000453:epidemiology / Q000628:therapy*; D035002:Lower Extremity / Q000098:blood supply*; D058729:Peripheral Arterial Disease / Q000453:epidemiology / Q000628:therapy*