title: Results of infertility investigations and follow-up among 312 infertile women and their partners in Kigali, Rwanda.
abstract: The objectives of this study were to assess the outcome of infertility investigations and an 18-month follow-up of 312 infertile women and their partners in Rwanda. Between November 2007 and May 2009, an infertility research clinic was opened. Infertile couples received basic infertility investigations, the available treatment was provided and couples were followed up over an 18-month period. The infertility remained unexplained in 3%, was due to a female factor in 31%, due to a male factor in 16% or due to a combination of male and female causes in 50% of fully investigated couples (n = 224). A tubal factor was found in 69% of women, a male factor in 64% of men. Predictors for tubal infertility in women included a history of high-risk sexual behaviour, HIV infection and a history of sexually transmitted infection (STI) symptoms in the male partner. After 12-18 months of follow-up, 40 pregnancies (16%) had occurred in 244 women. Our study shows high rates of tubal and male factor infertility in Rwanda. Pregnancy rates were low after conventional therapy. In order to provide effective and affordable treatment for infertility in resource-poor countries the development of low-cost assisted reproductive technologies are needed.
authors.affiliation: International Centre for Reproductive Health, Ghent University, Belgium. dhontnathalie@gmail.com
authors.forename: Nathalie
authors.initials: N
authors.lastname: Dhont
authors.forename: Janneke
authors.initials: J
authors.lastname: van de Wijgert
authors.forename: Joseph
authors.initials: J
authors.lastname: Vyankandondera
authors.forename: Rosette
authors.initials: R
authors.lastname: Busasa
authors.forename: Ammiel
authors.initials: A
authors.lastname: Gasarabwe
authors.forename: Marleen
authors.initials: M
authors.lastname: Temmerman
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006784:Hospitals, Teaching; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D007248:Infertility, Male / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D010535:Laparoscopy; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D015995:Prevalence; D012307:Risk Factors; D012432:Rwanda / Q000453:epidemiology; D012747:Sexual Partners / Q000523:psychology; D012959:Socioeconomic Factors