title: Idiopathic Parkinson's disease patients at the urologic clinic.
abstract: OBJECTIVE
  To quantitatively evaluate the urinary symptoms at different stages of idiopathic Parkinson's disease (IPD) severity and its relation to urodynamic parameters.
  
  
  METHODS
  This study was conducted on 49 patients with probable IPD to quantitatively evaluate their urinary symptoms using International Prostate Symptom Score and urodynamic tests. Four, 10, 29, 5, and 1 cases were classified as stages 1-5, respectively, according to Hoehn and Yahr staging of IPD severity.
  
  
  RESULTS
  The most prevailing urinary symptom in IPD was nocturia (77.5%) followed by urgency (36.7%) and frequency (32.6%). Urodynamic tests revealed neurogenic detrusor overactivity in 33 patients (67.3%), detrusor underactivity in 6 patients (12.2%), and 10 (20.4%) patients with normal detrusor function. Irritative symptom index score correlated significantly with disease severity as well as the volume at initial desire to void and maximum bladder capacity meanwhile obstructive symptom index score had no significant correlation with any of the urodynamic parameters or disease severity. Total IPSS symptoms score significantly correlated with quality of life score. The mean of urodynamic parameters did not differ in IPD patients who did or did not receive anticholinergic or dopaminergic drugs.
  
  
  CONCLUSIONS
  The irritative urinary symptoms manifested urodynamically as neurogenic detrusor overactivity are more common in IPD patients than obstructive symptoms. These irritative symptoms deteriorate progressively with the disease severity and significantly affect the quality of life of these patients. The International Prostate Symptom Score is a valuable tool in evaluating the urinary dysfunction in such patients.
authors.affiliation: Department of Urology, Tanta University, Tanta, Egypt. mmregy@yahoo.com
authors.forename: Maged M
authors.initials: MM
authors.lastname: Ragab
authors.forename: Ehab S
authors.initials: ES
authors.lastname: Mohammed
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D018450:Disease Progression; D004534:Egypt; D005260:Female; D006305:Health Status Indicators; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000209:etiology / Q000503:physiopathology; D010300:Parkinson Disease / Q000150:complications* / Q000503:physiopathology; D011237:Predictive Value of Tests; D011467:Prostate / Q000503:physiopathology; D011788:Quality of Life; D012720:Severity of Illness Index; D001743:Urinary Bladder / Q000294:innervation*; D053201:Urinary Bladder, Overactive / Q000209:etiology / Q000503:physiopathology; D053202:Urinary Incontinence, Urge / Q000209:etiology / Q000503:physiopathology; D014555:Urination Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014563:Urodynamics; D014573:Urology Department, Hospital