title: [Evaluations of pre-thromboembolic state in patients undergoing total abdominal or laparoscopic hysterectomy].
abstract: OBJECTIVE
  To investigate the influences of total abdominal and laparoscopically hysterectomy on coagulation and fibrinolytic functions.
  
  
  METHODS
  Blood samples were taken from 20 patients without high-risk factor of thrombosis before and after total abdominal and laparoscopically hysterectomy. The values of PT, APTT, FG, D-Dimer and AT-III were measured.
  
  
  RESULTS
  The values of PT and AT-III significantly decreased while D-Dimer significantly increased after the operations. These changes were more obvious in patients undergoing abdominal hysterectomy. No significant changes in APTT or FG were noted after hysterectomy.
  
  
  CONCLUSIONS
  Patients undergoing hysterectomy are at risk of developing thromboembolism, but the laparoscopic approach can significantly lower this risk as compared with abdominal hysterectomy.
authors.affiliation: Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. gyfgz007@126.com
authors.forename: Yun-fei
authors.initials: YF
authors.lastname: GAO
authors.forename: Guang-liang
authors.initials: GL
authors.lastname: ZHANG
authors.forename: Mei
authors.initials: M
authors.lastname: ZHONG
authors.forename: Jian
authors.initials: J
authors.lastname: LIU
mesh_terms: D001780:Blood Coagulation Tests; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects* / Q000379:methods; D010535:Laparoscopy / Q000009:adverse effects*; D010314:Partial Thromboplastin Time; D012307:Risk Factors; D013923:Thromboembolism / Q000175:diagnosis* / Q000209:etiology