title: Primary retroperitoneal dysgerminoma presenting as an adrenal tumor: a case report and literature review.
abstract: Primary extragonadal germ cell tumors are rare and mostly occur in young men with predominance of nonseminomatous histology. We report an undescribed case of primary retroperitoneal dysgerminoma presenting as an adrenal tumor in a 17-year-old girl. Surgery was performed on a 10 × 9.5 cm sized adrenal gland tumor and the resected tumor showed unequivocal histological features of dysgerminoma. The diagnosis was confirmed by the tumor's germ cell immunophenotype. Postoperative ultrasonography, CT and PET over a 6-month period revealed no evidence of ovarian lesion. The patient is stable, but with a suspicious residual tumor after adjuvant chemotherapy.
authors.affiliation: Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Su Hyun
authors.initials: SH
authors.lastname: Yoo
authors.forename: Kyu-Rae
authors.initials: KR
authors.lastname: Kim
authors.forename: Suk Jun
authors.initials: SJ
authors.lastname: Hong
authors.forename: Kyung-Ja
authors.initials: KJ
authors.lastname: Cho
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D000315:Adrenalectomy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007150:Immunohistochemistry; D012186:Retroperitoneal Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D014747:Vinblastine / Q000008:administration & dosage
chemical_list: D014408:Biomarkers, Tumor; D014747:Vinblastine; D002945:Cisplatin; D007069:Ifosfamide