title: Fetal cerebral ventricle volumetry: comparison between 3D ultrasound and magnetic resonance imaging in fetuses with ventriculomegaly.
abstract: OBJECTIVE
  The aim of this study was to evaluate feasibility of fetal lateral ventricle (LV) volumetry in fetuses with ventriculomegaly and to compare measurements performed by 3D sonographic method virtual organ computer-aided analysis (VOCAL) with those obtained by magnetic resonance imaging (MRI).
  
  
  METHODS
  This cross-sectional study evaluated 30 fetuses with atrial width (AW) between 10 and 30 mm, from 20 to 36 gestational weeks. Fifty-nine ventricles were measured by two observers. Sonographic volumetric measurements using VOCAL 30° were performed with an ACCUVIX XQ machine (Medison, Korea) and MRI assessments with a Sonata system using ARGUS software (Siemens, Germany). Agreement between both techniques was assessed by intraclass correlation coefficient (ICC) calculation, and proportionate Bland-Altman plots were constructed.
  
  
  RESULTS
  A high degree of reliability was observed between VOCAL and MRI measurements (ICC 0.928, 95%CI [0.876;0.958]). Bland-Altman plots confirmed the high correlation (mean of differences: 1.62 cm(3) and standard deviation: ± 8.41 cm(3)).
  
  
  CONCLUSIONS
  Three-dimensional volumetry of fetal LVs by VOCAL method has good agreement with fetal MRI in fetuses with ventriculomegaly and may be used as an additional tool in patient counseling and prognosis prediction.
authors.affiliation: Fetal Neurology sector of the Department of Obstetrics of the Federal University of São Paulo UNIFESP, São Paulo, Brazil. ninakrajden@gmail.com
authors.forename: Karina K
authors.initials: KK
authors.lastname: Haratz
authors.forename: Patricia S
authors.initials: PS
authors.lastname: Oliveira
authors.forename: Liliam C
authors.initials: LC
authors.lastname: Rolo
authors.forename: Luciano Mm
authors.initials: LM
authors.lastname: Nardozza
authors.forename: Hérbene F
authors.initials: HF
authors.lastname: Milani
authors.forename: Enoch Q
authors.initials: EQ
authors.lastname: Barreto
authors.forename: Edward
authors.initials: E
authors.lastname: Araujo Júnior
authors.forename: Sergio A
authors.initials: SA
authors.lastname: Ajzen
authors.forename: Antonio F
authors.initials: AF
authors.lastname: Moron
mesh_terms: D000293:Adolescent; D000328:Adult; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging / Q000196:embryology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000196:embryology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011379:Prognosis; D016216:Ultrasonography, Prenatal / Q000379:methods