title: Conjugate additions to alkylidene bis(sulfoxides).
abstract: A general study on the conjugate addition of anionic nucleophiles to alkylidene bis(sulfoxides) is presented. Alkoxides gave high yielding and diastereoselective addition reactions, which could be influenced by solvents and the counteranion. Azides provided an interesting entry into sulfinyl-substituted triazoles. Organometallics, mainly copper reagents, proved also to be valuable nucleophiles, and complete inversion of the stereoselectivity was achieved in the addition reaction with the latter. Modelizations provide a rationale for the observed diastereoselectivity.
authors.affiliation: UPMC University Paris 06, Institut Parisien de Chimie Moléculaire (UMR CNRS 7201), 4 place Jussieu, C. 229, 75005 Paris, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Brebion
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vincent
authors.forename: Saloua
authors.initials: S
authors.lastname: Chelli
authors.forename: Ophélie
authors.initials: O
authors.lastname: Kwasnieski
authors.forename: Francisco
authors.initials: F
authors.lastname: Najera
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Delouvrié
authors.forename: Ilan
authors.initials: I
authors.lastname: Marek
authors.forename: Etienne
authors.initials: E
authors.lastname: Derat
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Goddard
authors.forename: Max
authors.initials: M
authors.lastname: Malacria
authors.forename: Louis
authors.initials: L
authors.lastname: Fensterbank