title: Regulation of toxin production by Bacillus cereus and its food safety implications.
abstract: Toxin expression is of utmost importance for the food-borne pathogen B. cereus, both in food poisoning and non-gastrointestinal host infections as well as in interbacterial competition. Therefore it is no surprise that the toxin gene expression is tightly regulated by various internal and environmental signals. An overview of the current knowledge regarding emetic and diarrheal toxin transcription and expression is presented in this review. The food safety aspects and management tools such as temperature control, food preservatives and modified atmosphere packaging are discussed specifically for B. cereus emetic and diarrheal toxin production.
authors.affiliation: Ghent University, Faculty of Bioscience Engineering, Laboratory of Food Microbiology and Food Preservation, Ghent, Belgium.
authors.forename: Siele
authors.initials: S
authors.lastname: Ceuppens
authors.forename: Andreja
authors.initials: A
authors.lastname: Rajkovic
authors.forename: Marc
authors.initials: M
authors.lastname: Heyndrickx
authors.forename: Varvara
authors.initials: V
authors.lastname: Tsilia
authors.forename: Tom
authors.initials: T
authors.lastname: Van De Wiele
authors.forename: Nico
authors.initials: N
authors.lastname: Boon
authors.forename: Mieke
authors.initials: M
authors.lastname: Uyttendaele
mesh_terms: D001409:Bacillus cereus / Q000235:genetics / Q000472:pathogenicity*; D001427:Bacterial Toxins / Q000096:biosynthesis*; D005516:Food Microbiology; D059022:Food Safety / Q000379:methods*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans
chemical_list: D001427:Bacterial Toxins