title: Urothelial carcinoma of the renal pelvis associated with cystic disease of the kidney.
abstract: Primary tumors of the renal pelvis and ureter account for about 8% of all urinary tract tumors. More than 90% of them are urothelial carcinomas. On the other hand, unilateral multicystic renal disease is an uncommon pathologic condition that may be mistaken for unilateral autosomal dominant polycystic kidney disease, multilocular cystic nephroma or cystic neoplasm. We present the case of a 54-year-old male known with arterial hypertension, admitted in the Second Surgery Department of Emergency County Hospital, Constanta, with intense right flank and right lumbar pain. This symptom started one month before hospital admission. Based on clinical features and imaging evaluations we established a presumptive diagnosis of unilateral autosomal dominant polycystic kidney disease. For these reasons, total right nephrectomy was performed. Pathologic examination of the nephrectomy specimen revealed high-grade urothelial carcinoma of the renal pelvis associated with unilateral multicystic renal disease. The particularity of this case lies in the uncommon association between two rare renal pathological conditions diagnosed by pathological examination.
authors.affiliation: Department of Pathology, Emergency County Hospital, Constanta, Romania. deacu_mariana@yahoo.com
authors.forename: Mariana
authors.initials: M
authors.lastname: Deacu
authors.forename: Mădălina
authors.initials: M
authors.lastname: Boşoteanu
authors.forename: Mariana
authors.initials: M
authors.lastname: Aşchie
authors.forename: Gabriela
authors.initials: G
authors.lastname: Băltăţescu
authors.forename: V
authors.initials: V
authors.lastname: Sârbu
authors.forename: Mariana
authors.initials: M
authors.lastname: Bărdaş
mesh_terms: D049109:Cell Proliferation; D006801:Humans; D007633:Keratins / Q000378:metabolism; D052177:Kidney Diseases, Cystic / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D007680:Kidney Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D007682:Kidney Pelvis / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed; D019459:Urothelium / Q000000981:diagnostic imaging / Q000473:pathology*
chemical_list: D007633:Keratins