title: Valproate in acute mania - a controlled study.
abstract: A controlled blind study was carried out to establish the efficacy of Sodium Valproate as the first line of treatment in Acute Mania. Patients were studied over a period of 4 weeks. Using randomised table patients were assigned to either lithium or valproate. Decrease in the psychopathology was evident within 2-3 weeks. Valproate was found to be as effective as Lithium in controlling the manic episode.
authors.affiliation: H.M. PRAKASH, DPM., Senior Research Fellow, Department of Psychiatry, NIMHANS, Bangalore-560 029.
authors.forename: H M
authors.initials: HM
authors.lastname: Prakash
authors.forename: S
authors.initials: S
authors.lastname: Bharath