title: Reye syndrome and liver transplantation.
abstract: Reye syndrome is a rare, but severe and often fatal disease. The etiology of the classical Reye syndrome is unknown, but it is typically preceded by a viral infection with a free interval of three to five days. The main physiopathological hypothesis is a mitochondrial metabolism insult causing acute liver failure and encephalopathy. Survivors present serious neurological sequelae. The treatment of Reye syndrome is usually medical with intensive care management. Herein, we present the clinical case of a six-month-old baby diagnosed with Reye syndrome with a fulminant hepatitis, who was successfully liver transplanted with an auxiliary partial orthotopic liver transplantation.
authors.affiliation: Department of Liver Diseases, Gastroenterologic Surgery and Multiorgan Transplantation, Multiorgan Transplantation Unit, Hautepierre Hospital, University of Strasbourg.
authors.forename: Murat
authors.initials: M
authors.lastname: Cağ
authors.forename: Anne-Catherine
authors.initials: AC
authors.lastname: Saouli
authors.forename: Maxime
authors.initials: M
authors.lastname: Audet
authors.forename: Philippe
authors.initials: P
authors.lastname: Wolf
authors.forename: Jacques
authors.initials: J
authors.lastname: Cinqualbre
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D017114:Liver Failure, Acute / Q000139:chemically induced / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D012202:Reye Syndrome / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin