title: Buckling resistance of solid shell bubbles under ultrasound.
abstract: Thin solid shell contrast agents bubbles are expected to undergo different volume oscillating behaviors when the acoustic power is increased: small oscillations when the shell remains spherical, and large oscillations when the shell buckles. Contrary to bubbles covered with thin lipidic monolayers that buckle as soon as compressed: the solid shell bubbles resist compression, making the buckling transition abrupt. Numerical simulations that explicitly incorporate a shell bending modulus give the critical buckling pressure and post-buckling shape, and show the appearance of a finite number of wrinkles. These findings are incorporated in a model based on the concept of effective surface tension. This model compares favorably to experiments when adjusting two main parameters: the buckling tension and the rupture shell tension. The buckling tension provides a direct estimation of the acoustic pressure threshold at which buckling occurs.
authors.affiliation: Laboratoire Interdisciplinaire de Physique, CNRS-Université de Grenoble, 140 av de la Physique, 38402 Saint Martin d'Hères, France. Philippe.Marmottant@ujf-grenoble.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Marmottant
authors.forename: Ayache
authors.initials: A
authors.lastname: Bouakaz
authors.forename: Nico
authors.initials: N
authors.lastname: de Jong
authors.forename: Catherine
authors.initials: C
authors.lastname: Quilliet
mesh_terms: D000418:Albumins; D003198:Computer Simulation; D003287:Contrast Media; D055119:Elastic Modulus; D045423:Microbubbles; D008962:Models, Theoretical; D009716:Numerical Analysis, Computer-Assisted; D011091:Polyesters; D011312:Pressure; D013500:Surface Tension; D014463:Ultrasonography
chemical_list: D000418:Albumins; D003287:Contrast Media; C522044:PB-127 compound; D011091:Polyesters