title: Massive thrombi on an implantable cardioverter-defibrillator lead in a patient with the antiphospholipid syndrome.
abstract: A patient with the antiphospholipid syndrome, who was suboptimally anticoagulated, presented with two large thrombi attached to her implantable cardioverter-defibrillator lead. Anticoagulation was unsuccessful so, in view of the risk from embolization, the system was removed surgically and an epicardial system implanted to reduce the risk of future device-related thrombosis.
authors.affiliation: Department of Cardiology, St Thomas' Hospital, London, UK. waqas@doctors.org.uk
authors.forename: Waqas
authors.initials: W
authors.lastname: Ullah
authors.forename: John B
authors.initials: JB
authors.lastname: Chambers
authors.forename: Beverley J
authors.initials: BJ
authors.lastname: Hunt
authors.forename: Christopher
authors.initials: C
authors.lastname: Blauth
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Rinaldi
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications*; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D020878:Device Removal; D004699:Endocardium; D005260:Female; D006801:Humans; D008875:Middle Aged; D010496:Pericardium; D013927:Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin