title: Dietary flavonoids as cancer prevention agents.
abstract: Dietary agents identified from fruits and vegetables contribute to keeping balanced cell proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other components such as various vitamins, play an important role in cancer prevention. Flavonoids act on reactive oxygen species, cell signal transduction pathways related to cellular proliferation, apoptosis, and angiogenesis. Many studies demonstrate that flavonoids are responsible for chemoprevention, although mechanisms of action remain to be investigated. Overall, exciting data show that dietary flavonoids could be considered as a useful cancer preventive approach. This review summarizes recent advancements on potential cancer preventive effects and mechanic insight of dietary flavonoids.
authors.affiliation: Department of Stomatology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Yao
authors.forename: Weizheng
authors.initials: W
authors.lastname: Xu
authors.forename: Xianglin
authors.initials: X
authors.lastname: Shi
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D016588:Anticarcinogenic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D002392:Catechin / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D002453:Cell Cycle / Q000187:drug effects; D003474:Curcumin / Q000008:administration & dosage / Q000494:pharmacology; D004032:Diet; D005419:Flavonoids / Q000008:administration & dosage / Q000494:pharmacology*; D005502:Food; D006801:Humans; D017879:Isothiocyanates / Q000008:administration & dosage / Q000494:pharmacology; D009389:Neovascularization, Pathologic / Q000517:prevention & control; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D016588:Anticarcinogenic Agents; D005419:Flavonoids; D017879:Isothiocyanates; D002392:Catechin; C045651:epigallocatechin gallate; D003474:Curcumin