title: An evolutionarily conserved pseudokinase mediates stem cell production in plants.
abstract: Sequence comparisons, biochemical experiments, and studies with mutants in transgenic plants show that the Arabidopsis protein CORYNE, currently thought to be a kinase that acts as part of a receptor kinase complex, is likely to be a pseudokinase and not a kinase.
authors.affiliation: Division of Biology 156-29, California Institute of Technology, Pasadena, California 91125, USA.
authors.forename: Zachary L
authors.initials: ZL
authors.lastname: Nimchuk
authors.forename: Paul T
authors.initials: PT
authors.lastname: Tarr
authors.forename: Elliot M
authors.initials: EM
authors.lastname: Meyerowitz
mesh_terms: D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D003001:Cloning, Molecular; D019143:Evolution, Molecular; D018506:Gene Expression Regulation, Plant; D005816:Genetic Complementation Test; D008565:Membrane Proteins / Q000378:metabolism; D009154:Mutation; D030821:Plants, Genetically Modified / Q000201:enzymology / Q000235:genetics; D017346:Protein Serine-Threonine Kinases; D020794:Receptor Protein-Tyrosine Kinases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D011956:Receptors, Cell Surface; D011993:Recombinant Fusion Proteins; D015398:Signal Transduction; D013234:Stem Cells / Q000502:physiology; D019076:Transgenes
chemical_list: C118167:AT2G27250 protein, Arabidopsis; D029681:Arabidopsis Proteins; C401621:CLV2 protein, Arabidopsis; D008565:Membrane Proteins; D011956:Receptors, Cell Surface; D011993:Recombinant Fusion Proteins; D020794:Receptor Protein-Tyrosine Kinases; C118166:CLV1 protein, Arabidopsis; C548152:CORYNE protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases