title: [Proteomic technology: its progress and application in microcirculation research].
abstract: Microcirculation spreads all over the body, participates in material, energy, and information transmission directly. It is closely related to pathogenesis, development and prognosis of heart, brain and peripheral vascular diseases, diabetes, connective tissue disease and participates in many pathological processes, such as trauma, infection and shock. Its function changes involve a variety of interactions between cytokines and proteins, which are dynamic, complex and subtle. As a new branch of science, proteomics investigates cell protein composition and interaction disciplines as a whole. This technology helps to clarify the molecular mechanism of microcirculation changes during physiological or pathological conditions. This paper reviews the recent progress of proteomics technology and its application in studies of microcirculation.
authors.affiliation: Department of Pathophysiology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Fei-Fei
authors.initials: FF
authors.lastname: Xu
authors.forename: Xiu-Hua
authors.initials: XH
authors.lastname: Liu
mesh_terms: D000818:Animals; D006801:Humans; D008833:Microcirculation / Q000502:physiology*; D040901:Proteomics / Q000379:methods* / Q000639:trends*