title: Sensorimotor integration and psychopathology: motor control abnormalities related to psychiatric disorders.
abstract: OBJECTIVE
  Recent evidence is reviewed to examine relationships among sensorimotor and cognitive aspects in some important psychiatry disorders. This study reviews the theoretical models in the context of sensorimotor integration and the abnormalities reported in the most common psychiatric disorders, such as Alzheimer's disease, autism spectrum disorder and squizophrenia.
  
  
  METHODS
  The bibliographical search used Pubmed/Medline, ISI Web of Knowledge, Cochrane data base and Scielo databases. The terms chosen for the search were: Alzheimer's disease, AD, autism spectrum disorder, and Squizophrenia in combination with sensorimotor integration. Fifty articles published in English and were selected conducted from 1989 up to 2010.
  
  
  RESULTS
  We found that the sensorimotor integration process plays a relevant role in elementary mechanisms involved in occurrence of abnormalities in most common psychiatric disorders, participating in the acquisition of abilities that have as critical factor the coupling of different sensory data which will constitute the basis of elaboration of consciously goal-directed motor outputs. Whether these disorders are associated with an abnormal peripheral sensory input or defective central processing is still unclear, but some studies support a central mechanism.
  
  
  CONCLUSIONS
  Sensorimotor integration seems to play a significant role in the disturbances of motor control, like deficits in the feedforward mechanism, typically seen in AD, autistic and squizophrenic patients.
authors.affiliation: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil. bruna_velasques@yahoo.com.br
authors.forename: Bruna
authors.initials: B
authors.lastname: Velasques
authors.forename: Sergio
authors.initials: S
authors.lastname: Machado
authors.forename: Flávia
authors.initials: F
authors.lastname: Paes
authors.forename: Marlo
authors.initials: M
authors.lastname: Cunha
authors.forename: Antonio
authors.initials: A
authors.lastname: Sanfim
authors.forename: Henning
authors.initials: H
authors.lastname: Budde
authors.forename: Mauricio
authors.initials: M
authors.lastname: Cagy
authors.forename: Renato
authors.initials: R
authors.lastname: Anghinah
authors.forename: Luis F
authors.initials: LF
authors.lastname: Basile
authors.forename: Roberto
authors.initials: R
authors.lastname: Piedade
authors.forename: Pedro
authors.initials: P
authors.lastname: Ribeiro
mesh_terms: D000544:Alzheimer Disease / Q000503:physiopathology; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000503:physiopathology; D044127:Epigenesis, Genetic / Q000502:physiology; D056228:Feedback, Sensory / Q000502:physiology*; D006801:Humans; D001523:Mental Disorders / Q000503:physiopathology*; D009069:Movement Disorders / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology; D055139:Sensory Gating / Q000502:physiology