title: Fetal and neonatal presentation of long QT syndrome.
abstract: This report describes a fetus presenting with intrauterine tachycardia and hydrops fetalis. Soon after birth the neonate was noted to be in torsades de pointes that responded dramatically to medical management. Long QT syndrome (LQTS) was diagnosed on electrocardiogram obtained soon after birth. The prognosis is poor when LQTS presents in utero or during the first week of life. However, our infant did well with medical management and has remained free of arrhythmias at follow-up.
authors.affiliation: Department of Pediatric Cardiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, USA.
authors.forename: Rukmini
authors.initials: R
authors.lastname: Komarlu
authors.forename: Lee
authors.initials: L
authors.lastname: Beerman
authors.forename: David
authors.initials: D
authors.lastname: Freeman
authors.forename: Gaurav
authors.initials: G
authors.lastname: Arora
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000072237:ERG1 Potassium Channel; D004562:Electrocardiography; D051638:Ether-A-Go-Go Potassium Channels / Q000235:genetics; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology; D005333:Fetus / Q000503:physiopathology*; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis / Q000503:physiopathology; D007231:Infant, Newborn; D007545:Isoproterenol / Q000627:therapeutic use; D008012:Lidocaine / Q000627:therapeutic use; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology; D008297:Male; D016171:Torsades de Pointes / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D000889:Anti-Arrhythmia Agents; D000072237:ERG1 Potassium Channel; D051638:Ether-A-Go-Go Potassium Channels; D008012:Lidocaine; D007545:Isoproterenol