title: Primary anal mucinous adenocarcinoma: a case series.
abstract: Primary mucinous adenocarcinoma is a rare malignancy of the anus (3% of anal cancers), the pathogenesis of which is better understood by immunohistochemistry. We reviewed cases of primary mucinous adenocarcinoma of the anus from 2000 to 2009 in the Hepatogastroenterology Department of the University Hospital Centre of Marrakech. Three cases were identified who were males with the mean age of 68years, and presented with a chronic anal fistula. Two cases had anal pain. Clinical examination revealed multiple fistulae in two cases with a secretion simulating 'cooked grains of tapioca'. Diagnosis was confirmed by histopathology and immunohistochemical profile (CK7 positive/CK20 negative). Imaging revealed a retro-rectal collection with thickening of the anal wall without metastasis (two cases). One patient underwent abdominoperinal resection without recurrence.
authors.affiliation: Gastroenterology Department, UHC Mohamed VI Qaddi Ayyad University, Marrakech, Morocco. drdiffaa@hotmail.fr
authors.forename: Azeddine
authors.initials: A
authors.lastname: Diffaa
authors.forename: Zouhour
authors.initials: Z
authors.lastname: Samlani
authors.forename: Abouch
authors.initials: A
authors.lastname: Elbahlouli
authors.forename: Khalid
authors.initials: K
authors.lastname: Rabbani
authors.forename: Youssef
authors.initials: Y
authors.lastname: Narjis
authors.forename: Fadoua
authors.initials: F
authors.lastname: Elamansouri
authors.forename: Salwa
authors.initials: S
authors.lastname: Ettalbi
authors.forename: Elhassan
authors.initials: E
authors.lastname: Boukind
authors.forename: Badia
authors.initials: B
authors.lastname: Belabidia
authors.forename: Hamid
authors.initials: H
authors.lastname: El Idrissi
authors.forename: Khadija
authors.initials: K
authors.lastname: Krati
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis* / Q000601:surgery; D000368:Aged; D001005:Anus Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D012003:Rectal Fistula / Q000209:etiology / Q000601:surgery