title: [A follow-up study on cognitive changes of mild cognitive impairment in the elderly].
abstract: OBJECTIVE
  To observe and assess the cognitive changes of mild cognitive impairment (MCI) in the elderly.
  
  
  METHODS
  A cohort study design was conducted among 47 patients with MCI and 21 control selected from the same convalescent camp, Montreal cognitive assessment (MoCA), mini mental state examination (MMSE) and clock drawing test (CDT) were performed to all subjects at the onset of study and 12 months later.
  
  
  RESULTS
  The score of MMSE, CDT, MoCA and its subitems including visuospatial skill and delayed recall of MCI group were lower than the baseline after 12 months, with significantly decline in the score of MoCA (P = 0.041) and delay recall (P = 0.003). There was no obvious difference in the score of control between the baseline and that after 12 months.
  
  
  CONCLUSIONS
  The decline of delayed recall occurred early and significantly, which may be a predictor in the conversion of mild cognitive impairment to dementia.
authors.affiliation: Department of Neurology of Nanlou Division, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Zhong-Bao
authors.initials: ZB
authors.lastname: Gao
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Xing-Li
authors.initials: XL
authors.lastname: Zhao
authors.forename: Yan-Chang
authors.initials: YC
authors.lastname: Shang
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Bai
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Wu
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests