title: Diabetic retinopathy: current developments in pathogenesis and management.
abstract: Diabetic retinopathy is now an important cause of visual impairment in the developing countries due to changing lifestyles. This review includes recent developments on the pathogenesis of diabetic retinopathy emphasizing the role of Protein Kinase C and Vascular Endothelial Growth Factor. It also bring to the fore the atypical presentations, recent use of pharmacological agents and the importance of screening in the management of diabetic retinopathy. These developments are relevant in Nigeria, and Ophthalmic and Medical practitioners need to be aware.
authors.affiliation: Retina and Vitreous Unit, Department of Ophthalmology, University College Hospital, P M B 5116, Ibadan, Nigeria. t_oluleye@yahoo.co.uk
authors.forename: T S
authors.initials: TS
authors.lastname: Oluleye
mesh_terms: D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D003930:Diabetic Retinopathy / Q000473:pathology* / Q000628:therapy*; D019468:Disease Management; D006801:Humans; D017075:Laser Coagulation; D008403:Mass Screening; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*
chemical_list: D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D000975:Antioxidants; D042461:Vascular Endothelial Growth Factor A; D011493:Protein Kinase C