title: Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010.
abstract: The fourth Leon Thal Symposium (LTS2010) was convened in Toulouse, France, on November 3, 2010. This symposium reviewed design parameters that are necessary to develop comprehensive national databases on healthy aging. Such datasets offer the potential to serve as the foundation for a systems-approach to solve the dual public health problems of: (1) early detection of people who are at elevated risk for Alzheimer's disease, and (2) the development of interventions to delay onset of, or prevent, late-life dementia. The symposium considered three interrelated components of a National Database for Longitudinal Studies on Healthy Aging as follows: (a) a registry of healthy aging adults; (b) refined computer-based assessments for data gathering, including assessments of behavioral/memory changes associated with aging that are appropriate for broad use in nonexpert settings; and (c) high performance computing/supercomputer-based approaches for health data modeling and mining.
authors.affiliation: The Campaign to Prevent Alzheimer's Disease by 2020, Rockville, MD, USA. zaven@pad2020.org
authors.forename: Zaven S
authors.initials: ZS
authors.lastname: Khachaturian
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Petersen
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Snyder
authors.forename: Ara S
authors.initials: AS
authors.lastname: Khachaturian
authors.forename: Paul
authors.initials: P
authors.lastname: Aisen
authors.forename: Mony
authors.initials: M
authors.lastname: de Leon
authors.forename: Barry D
authors.initials: BD
authors.lastname: Greenberg
authors.forename: Walter
authors.initials: W
authors.lastname: Kukull
authors.forename: Paul
authors.initials: P
authors.lastname: Maruff
authors.forename: Reisa A
authors.initials: RA
authors.lastname: Sperling
authors.forename: Yaakov
authors.initials: Y
authors.lastname: Stern
authors.forename: Jacques
authors.initials: J
authors.lastname: Touchon
authors.forename: Bruno
authors.initials: B
authors.lastname: Vellas
authors.forename: Sandrine
authors.initials: S
authors.lastname: Andrieu
authors.forename: Michael W
authors.initials: MW
authors.lastname: Weiner
authors.forename: Maria C
authors.initials: MC
authors.lastname: Carrillo
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Bain
mesh_terms: D000544:Alzheimer Disease / Q000517:prevention & control*; D003226:Congresses as Topic; D014943:Global Health; D006801:Humans; D011315:Preventive Medicine / Q000379:methods* / Q000639:trends*; D012042:Registries