title: Treatment for atrophic macular degeneration.
abstract: OBJECTIVE
  To summarize ongoing and recently completed trials on geographic atrophy associated with age-related macular degeneration.
  
  
  RESULTS
  A large number of investigational agents are under development for treatment of geographic atrophy in both pre and early-phase clinical testing.
  
  
  CONCLUSIONS
  Therapies targeting all putative phases of pathogenesis in geographic atrophy are under development. Thus far, no therapies have been demonstrated to be effective.
authors.affiliation: National Eye Institute/National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Annal D
authors.initials: AD
authors.lastname: Meleth
authors.forename: Wai T
authors.initials: WT
authors.lastname: Wong
authors.forename: Emily Y
authors.initials: EY
authors.lastname: Chew
mesh_terms: D002986:Clinical Trials as Topic; D057092:Geographic Atrophy / Q000188:drug therapy*; D006801:Humans; D008268:Macular Degeneration / Q000188:drug therapy*; D012160:Retina / Q000473:pathology; D055213:Retinal Pigment Epithelium / Q000473:pathology