title: Plasmid typing and resistance profiling of Escherichia fergusonii and other Enterobacteriaceae isolates from South Korean farm animals.
abstract: In this study, we focused on determining the distribution and prevalence of major plasmid replicons in β-lactam-resistant Escherichia fergusonii and Enterobacteriaceae of animal and human origin. A high degree of plasmid variability and multiple plasmid replicons were observed among the isolates. The IncF and IncI1 replicons were the most prevalent in E. fergusonii and Salmonella enterica serovar Indiana isolated from swine and poultry in South Korea, respectively. The presence of broad-host-range plasmid replicons such as IncN, IncA/C, IncHI1, and IncHI2 that are associated with important virulence genes and toxins as well as antimicrobial resistance determinants indicates that E. fergusonii has the potential to become an important pig pathogen and possible emerging opportunistic zoonotic pathogen.
authors.affiliation: Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, San 56-1, Sillim 9 dong, Kwanak-Ku, 151-742 Seoul, South Korea.
authors.forename: Nabin
authors.initials: N
authors.lastname: Rayamajhi
authors.forename: Seung Bin
authors.initials: SB
authors.lastname: Cha
authors.forename: Seung Won
authors.initials: SW
authors.lastname: Shin
authors.forename: Byeong Yeal
authors.initials: BY
authors.lastname: Jung
authors.forename: Suk-Kyung
authors.initials: SK
authors.lastname: Lim
authors.forename: Han Sang
authors.initials: HS
authors.lastname: Yoo
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001427:Bacterial Toxins / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D014644:Genetic Variation; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000032:analysis*; D011200:Poultry / Q000382:microbiology; D012093:Replicon; D056910:Republic of Korea; D013552:Swine / Q000382:microbiology; D037521:Virulence Factors / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D037521:Virulence Factors