title: Ghrelin- and serotonin-producing gastric carcinoid.
abstract: We report the case of a 57-year-old woman with gastric carcinoid. The tumor was surgically removed and immunohistochemical investigation demonstrated a rare combination: ghrelin and serotonin in the cytoplasm of the tumor cells. The functional significance of simultaneous production of ghrelin and serotonin is not clear. It may be that an autocrine/paracrine interaction exists between these two different hormones.
authors.affiliation: Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, University of Toronto, Toronto, ON, M5B1W8, Canada.
authors.forename: Eleanor
authors.initials: E
authors.lastname: Latta
authors.forename: Fabio
authors.initials: F
authors.lastname: Rotondo
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Leiter
authors.forename: Eva
authors.initials: E
authors.lastname: Horvath
authors.forename: Kalman
authors.initials: K
authors.lastname: Kovacs
mesh_terms: D002276:Carcinoid Tumor / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D005356:Fibromyalgia / Q000150:complications; D015390:Gastric Bypass; D054439:Ghrelin / Q000096:biosynthesis*; D006801:Humans; D007150:Immunohistochemistry; D008275:Magnesium Deficiency / Q000150:complications; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D012701:Serotonin / Q000096:biosynthesis*; D013274:Stomach Neoplasms / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D014808:Vitamin D Deficiency / Q000150:complications
chemical_list: D054439:Ghrelin; D012701:Serotonin