title: [Research about the mechanism in masticatory muscle dysfunctional induced by hemimastication].
abstract: OBJECTIVE
  To study the mechanism in masticatory muscle dysfunctional induced by hemimastication.
  
  
  METHODS
  Ca2+ contents were measured with atomic absorption spectrometry; calcinuerin were measured with colorimetric method; muscle fiber types were measured with adenosine-triphosphate (ATPase) staining.
  
  
  RESULTS
  (1) Compared with the controls, Ca2+ contents in experimental group had the higher level except 8 weeks (P < 0.05). (2) The ratio of slow fiber in experimental group increased, higher than the match groups (P < 0.05). (3) With Ca2 contents rise, the activities of calcinuerin present a bell-like shape. (4) The ratio of slow-type fiber was positively correlated to the activities of calcinuerin (r = 0.876, P < 0.05).
  
  
  CONCLUSIONS
  The signal way of muscle fiber growth and fiber transformation were activated by high concentration of calcium, then, muscle fiber transferred from fast to slow type. It may play an important role in the mechanism that hemimastication result in masticatory muscles dysfunction.
authors.affiliation: Dept. of Prosthodontics, College of Stomatology, Shandong University, Jinan 250012, China.
authors.forename: Zi-xian
authors.initials: ZX
authors.lastname: Wang
authors.forename: Long-bo
authors.initials: LB
authors.lastname: Xu
authors.forename: Dong
authors.initials: D
authors.lastname: Qi
authors.forename: Xue-fen
authors.initials: XF
authors.lastname: Lin
authors.forename: Wang-gui
authors.initials: WG
authors.lastname: Ying
authors.forename: Sheng-jun
authors.initials: SJ
authors.lastname: Sun
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Ping
authors.initials: P
authors.lastname: Ji
mesh_terms: D000255:Adenosine Triphosphate; D002118:Calcium; D006801:Humans; D008409:Mastication; D008410:Masticatory Muscles
chemical_list: D000255:Adenosine Triphosphate; D002118:Calcium