title: Issues in the safety testing of metabolites.
authors.affiliation: Department of Clinical Pharmacology, Drug Metabolism and Pharmacokinetics, AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire, UK. gerhard.gross@astrazeneca.com
authors.forename: Gerhard
authors.initials: G
authors.lastname: Gross
authors.forename: Ian
authors.initials: I
authors.lastname: Wilson
mesh_terms: D000818:Animals; D017277:Drug Approval; D004353:Drug Evaluation, Preclinical; D004345:Drug Industry; D064420:Drug-Related Side Effects and Adverse Reactions; D017408:Guidelines as Topic; D006801:Humans; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D012449:Safety; D014481:United States
chemical_list: D004364:Pharmaceutical Preparations