title: Pillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995.
authors.forename: Shimon
authors.initials: S
authors.lastname: Sakaguchi
authors.forename: Noriko
authors.initials: N
authors.lastname: Sakaguchi
authors.forename: Masanao
authors.initials: M
authors.lastname: Asano
authors.forename: Misako
authors.initials: M
authors.lastname: Itoh
authors.forename: Masaaki
authors.initials: M
authors.lastname: Toda
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000266:history*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology* / Q000473:pathology; D002478:Cells, Cultured; D004195:Disease Models, Animal; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D053645:Interleukin-2 Receptor alpha Subunit / Q000266:history*; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D017634:Self Tolerance / Q000276:immunology*
chemical_list: D053645:Interleukin-2 Receptor alpha Subunit