title: Reward improves long-term retention of a motor memory through induction of offline memory gains.
abstract: In humans, training in which good performance is rewarded or bad performance punished results in transient behavioral improvements. The relative effects of reward and punishment on consolidation and long-term retention, critical behavioral stages for successful learning, are not known. Here, we investigated the effects of reward and punishment on these different stages of human motor skill learning. We studied healthy subjects who trained on a motor task under rewarded, punished, or neutral control conditions. Performance was tested before and immediately, 6 hr, 24 hr, and 30 days after training in the absence of reward or punishment. Performance improvements immediately after training were comparable in the three groups. At 6 hr, the rewarded group maintained performance gains, whereas the other two groups experienced significant forgetting. At 24 hr, the reward group showed significant offline (posttraining) improvements, whereas the other two groups did not. At 30 days, the rewarded group retained the gains identified at 24 hr, whereas the other two groups experienced significant forgetting. We conclude that training under rewarded conditions is more effective than training under punished or neutral conditions in eliciting lasting motor learning, an advantage driven by offline memory gains that persist over time.
authors.affiliation: Human Cortical Physiology and Stroke Neurorehabilitation Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Mitsunari
authors.initials: M
authors.lastname: Abe
authors.forename: Heidi
authors.initials: H
authors.lastname: Schambra
authors.forename: Eric M
authors.initials: EM
authors.lastname: Wassermann
authors.forename: Dave
authors.initials: D
authors.lastname: Luckenbaugh
authors.forename: Nicolas
authors.initials: N
authors.lastname: Schweighofer
authors.forename: Leonardo G
authors.initials: LG
authors.lastname: Cohen
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007858:Learning; D008297:Male; D057567:Memory, Long-Term; D009043:Motor Activity; D009048:Motor Skills; D011678:Punishment; D012153:Retention, Psychology; D012201:Reward; D055815:Young Adult