title: Characteristics of J wave-associated idiopathic ventricular fibrillation: role of drugs.
abstract: A storm of J wave-associated idiopathic ventricular fibrillation (VF) was observed in a 49-year-old man. Multiform premature ventricular complexes initiated the episodes of VF. Intravenous isoproterenol attenuated the J wave and suppressed the VF storm. After the implantation of a cardioverter defibrillator, VF was induced by programmed electrical stimulation at baseline, and it was terminated by a 25-J shock after an unsuccessful 15-J shock. During oral treatment with quinidine sulfate, 600 mg daily, the J wave was attenuated and VF became noninducible by programmed electrical stimulation. VF induced by a shock delivered on the T wave was terminated by a single 10-J shock. Mean F-F interval and dominant frequency of the VF were 162 ms and 6.8 Hz at baseline, and 210 ms and 5.0 Hz during the quinidine sulfate treatment.
authors.affiliation: School of Health Science, First Department of Internal Medicine, Niigata University School of Medicine, Niigata, Japan. masaomi@clg.niigata-u.ac.jp
authors.forename: Masaomi
authors.initials: M
authors.lastname: Chinushi
authors.forename: Kanae
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Iijima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furushima
authors.forename: Daisuke
authors.initials: D
authors.lastname: Izumi
authors.forename: Akinori
authors.initials: A
authors.lastname: Sato
authors.forename: Yoshifusa
authors.initials: Y
authors.lastname: Aizawa
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D017147:Defibrillators, Implantable; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000627:therapeutic use*; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000188:drug therapy* / Q000209:etiology / Q000628:therapy; D018879:Ventricular Premature Complexes / Q000150:complications / Q000188:drug therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D002316:Cardiotonic Agents; D011802:Quinidine; D007545:Isoproterenol