title: Neoadjuvant chemotherapy used for colorectal liver and lung metastasis resections.
abstract: OBJECTIVE
  The aim of this study is to determine the hospital's efficiency as regards neoadjuvant chemotherapy for the resection of initially unresectable metastases for patients with metastatic primary colorectal cancer and to describe the chemotherapy used.
  
  
  METHODS
  Descriptive, retrospective study of patients with colorectal cancer from 2004 to 2007. The percentage of resection for metastases following neoadjuvant chemotherapy administration was studied.
  
  
  RESULTS
  Clinical histories of 118 patients diagnosed with metastatic colorectal cancer were reviewed. Metastases were initially resectable in ten patients (8.5%) and unresectable in the remaining 108 patients (91.5%). Following neoadjuvant chemotherapy, metastatic resection was performed on 19 patients.
  
  
  CONCLUSIONS
  Neoadjuvant chemotherapy played an important role in treating patients with disseminated metastatic colorectal cancer by reducing, in some cases, tumour size and treating initially unresectable metastases susceptible to subsequent surgical resection.FOLFOX scheme was the most used neoadjuvant chemotherapy treatment.
authors: Servicio de Farmacia, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain. ceichmt@mutuaterrassa.es
authors: S
authors: S
authors: Redondo Capafons
authors: A
authors: A
authors: Planas Giner
authors: R
authors: R
authors: Garriga Biosca
authors: R
authors: R
authors: Pla Poblador
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012189:Retrospective Studies