title: ROPES eye plaque brachytherapy dosimetry for two models of (103)Pd seeds.
abstract: Brachytherapy dose distributions are calculated for 15 mm ROPES eye plaque loaded with model Theragenics200 and IR06-(103)Pd seeds. The effects of stainless steel backing and Acrylic insert on dose distribution along the central axis of the eye plaque and at critical ocular structure are investigated. Monte Carlo simulation was carried out with the Version 5 of the MCNP. The dose at critical ocular structure by considering the eye composition was calculated. Results are compared with the calculated data for COMS eye plaque loaded with Theragenics200 palladium-103 seeds and model 6711 iodine-125 seed. The air kerma strength of the IR06-(103)Pd seed to deliver 85 Gy in apex of tumor in water medium was calculated to be 4.10 U/seed. Along the central axis of stainless steel plaque loaded with new (103)Pd seeds in Acrylic insert, the dose reduction relative to water is 6.9% at 5 mm (apex). Removal of the Acrylic insert from the plaque (replacing with water) did not make significantly difference in dose reduction results (~0.2%). The presence of the stainless steel backing results in dose enhancement near the plaque relative to water. Doses at points of interest are higher for ROPES eye plaque when compared to COMS eye plaque. The dosimetric parameters calculated in this work for the new palladium seed, showed that in dosimetry point of view, the IR06-(103)Pd seed is suitable for use in brachytherapy. The effect of Acrylic insert on dose distribution is negligible and the main effect on dose reduction is due to the presence of stainless steel plaque backing.
authors: Department of Nuclear Engineering, Research and Science Branch, Islamic Azad University, Tehran, Iran.
authors: Pooneh
authors: P
authors: Saidi
authors: Mahdi
authors: M
authors: Sadeghi
authors: Alireza
authors: A
authors: Shirazi
authors: Claudio
authors: C
authors: Tenreiro
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods*; D002830:Choroid Neoplasms / Q000532:radiotherapy*; D003198:Computer Simulation; D006801:Humans; D008545:Melanoma / Q000532:radiotherapy; D008954:Models, Biological; D009010:Monte Carlo Method; D010165:Palladium / Q000008:administration & dosage*; D011868:Radioisotopes / Q000008:administration & dosage*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D013193:Stainless Steel
chemical_list: D011868:Radioisotopes; D013193:Stainless Steel; D010165:Palladium