title: Intravascular lymphomatosis presenting as acute hemispheric dysfunction.
abstract: Intravascular lymphomatosis (IVL) is known to affect both hemispheres of the brain and manifests clinically as seizures or dementia. To our knowledge, there have been no cases in which acute hemispheric dysfunction is manifested in IVL. We present a 54-year-old man who showed steroid responsive acute hemispheric dysfunction. A technetium 99m-ethyl cysteinate dimer single-photon emission computed tomographic scan of the brain revealed hypoperfusion in the right hemisphere. The bone marrow biopsy specimen confirmed malignant lymphoid cells in vessels, which suggested IVL. Our case signifies the diversity of clinical manifestations in IVL.
authors: Department of Neurology, Samsung Medical Center, College of Medicine, Sungkyunkwan University, Seoul, Korea.
authors: Woo Sub
authors: WS
authors: Hwang
authors: Chul Won
authors: CW
authors: Jung
authors: Young Hye
authors: YH
authors: Ko
authors: Sang Won
authors: SW
authors: Seo
authors: Duk L
authors: DL
authors: Na
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D001856:Bone Marrow Examination; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D054022:Cerebrum / Q000098:blood supply / Q000503:physiopathology*; D003545:Cysteine / Q000031:analogs & derivatives; D017809:Fatal Outcome; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D012772:Shock, Septic / Q000209:etiology; D013256:Steroids / Q000627:therapeutic use; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013256:Steroids; C059659:technetium Tc 99m bicisate; D003545:Cysteine