title: MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma.
abstract: MicroRNAs have emerged as important regulators of cell proliferation, development, cancer formation, stress responses, cell death, and other physiological conditions in the past decade. On the other hand, head and neck cancer is one of the top ten most common cancers worldwide. Recent advances in microRNAs have revealed their prominent role in regulating gene expression and provided new aspects of applications in diagnosis, prognosis, and therapeutic strategies in head and neck squamous carcinoma. In the present paper, we focus on microRNAs showing significant differences between normal and tumor cells or between cells with differential ability of metastasis. We also emphasize specific microRNAs that could modulate tumor cell properties, such as apoptosis, metastasis, and proliferation. These microRNAs possess the potential to be applied on clinical therapy in the future.
authors: Institute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
authors: Li-Hsin
authors: LH
authors: Chen
authors: Kun-Ling
authors: KL
authors: Tsai
authors: Yi-Wei
authors: YW
authors: Chen
authors: Cheng-Chia
authors: CC
authors: Yu
authors: Kuo-Wei
authors: KW
authors: Chang
authors: Shi-Hwa
authors: SH
authors: Chiou
authors: Hung-Hai
authors: HH
authors: Ku
authors: Pen-Yuan
authors: PY
authors: Chu
authors: Ling-Ming
authors: LM
authors: Tseng
authors: Pin-I
authors: PI
authors: Huang
authors: Wen-Liang
authors: WL
authors: Lo