title: Syndromes with focal overgrowth in infancy: diagnostic approach and surgical treatment.
abstract: Syndromes with focal overgrowth are sporadic diseases and comprise Proteus syndrome and congenital lipomatous overgrowth, vascular malformations, and epidermal naevi (CLOVE) syndrome, and isolated hemihyperplasia. We describe 3 children classified according to standard criteria with dysregulated growth of various tissues that was excised, together with excess toes, and tumours. Correct classification facilitates diagnosis and operations. Interdisciplinary treatment and follow-up are recommended to prevent disfiguration.
authors: Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover.
authors: Ursula
authors: U
authors: Mirastschijski
authors: Silke
authors: S
authors: Altmann
authors: Olivia
authors: O
authors: Lenz-Scharf
authors: Petra
authors: P
authors: Muschke
authors: Wolfgang
authors: W
authors: Schneider
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000601:surgery*; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008068:Lipomatosis / Q000151:congenital / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D016715:Proteus Syndrome / Q000175:diagnosis / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D013577:Syndrome; D016896:Treatment Outcome; D054079:Vascular Malformations / Q000175:diagnosis / Q000601:surgery*