title: Subclinical elevations of thyroid-stimulating hormone and assisted reproductive technology outcomes.
abstract: The prevalence of moderately elevated TSH levels consistent with subclinical hypothyroidism (2.5-4.0 μIU/mL) was 23% in a cohort of 1,231 women pursuing assisted reproductive technologies. Preconception elevated levels of TSH were associated with diminished ovarian reserve but were not associated with adverse assisted reproductive technology or pregnancy outcomes.
authors: Eunice Kennedy Shriver National Institute of Child Health and Human Development, Program in Reproductive and Adult Endocrinology, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors: Konstantinos G
authors: KG
authors: Michalakis
authors: Tolga B
authors: TB
authors: Mesen
authors: Lynae M
authors: LM
authors: Brayboy
authors: Bo
authors: B
authors: Yu
authors: Kevin S
authors: KS
authors: Richter
authors: Michael
authors: M
authors: Levy
authors: Eric
authors: E
authors: Widra
authors: James H
authors: JH
authors: Segars
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D058070:Asymptomatic Diseases; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D010053:Ovary / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects; D012189:Retrospective Studies; D013972:Thyrotropin / Q000097:blood*; D016896:Treatment Outcome; D014481:United States; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D013972:Thyrotropin