title: Genome of Streptococcus oralis strain Uo5.
abstract: Streptococcus oralis, a commensal species of the human oral cavity, belongs to the Mitis group of streptococci, which includes one of the major human pathogens as well, S. pneumoniae. We report here the first complete genome sequence of this species. S. oralis Uo5, a high-level penicillin- and multiple-antibiotic-resistant isolate from Hungary, is competent for genetic transformation under laboratory conditions. Comparative and functional genomics of Uo5 will be important in understanding the evolution of pathogenesis among Mitis streptococci and their potential to engage in interspecies gene transfer.
authors: Department of Microbiology, University of Kaiserslautern, Paul Ehrlich Str. 23, D-67663 Kaiserslautern, Germany.
authors: Peter
authors: P
authors: Reichmann
authors: Michael
authors: M
authors: Nuhn
authors: Dalia
authors: D
authors: Denapaite
authors: Reinhold
authors: R
authors: Brückner
authors: Bernhard
authors: B
authors: Henrich
authors: Patrick
authors: P
authors: Maurer
authors: Martin
authors: M
authors: Rieger
authors: Sven
authors: S
authors: Klages
authors: Richard
authors: R
authors: Reinhard
authors: Regine
authors: R
authors: Hakenbeck
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D024901:Drug Resistance, Multiple, Bacterial; D016680:Genome, Bacterial; D006801:Humans; D006814:Hungary; D008969:Molecular Sequence Data; D009055:Mouth; D017422:Sequence Analysis, DNA; D019533:Streptococcus oralis / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D014169:Transformation, Bacterial
chemical_list: D004269:DNA, Bacterial