title: [Effect of the minor and moderate malnutrition on immunity, inflammatory and nutritional proteins at Côte d'Ivoire child].
abstract: This study was realiszed in Côte d'Ivoire at the children from 5 to 15 years old. The purpose of this study was to determine the alteration of immunity, inflammatory and nutritional proteins at 142 children (30 minor and 12 moderated malnutrition). The nutritional state or the state of malnutrition was to appreciate by Weight/height ratio which is the most usued by far. Immunity, inflammatory and nutritional proteins were measured by radical immunodiffusion according to Mancini. The results of this study showed that the Albumin was lowered (p<0.01) during the moderate and minor malnutrition in comparison to the children.On the other hand, it was observed an increased of CRP in both forms of malnutrition (p<0.05).Also, the index prognostic nutritional and inflammatory who, allows to appreciate simultaneously the inflammatory and nutritional state (PINI) was increased in the malnutrition moderated with regard to the minor malnutrition and to the children (p<0.05).Besides, immunity proteins remain unchanged in both forms of malnutrition in comparison to the healthy children (p<0.05). Finally, this study shows that the moderate and malnutrition are associated with an inflammatory process and of protein consumption notably the Albumin .These observations suggest that determination of the nutritional status requires the use of the clinical method coupled with the biological examinations.
authors: Laboratoire de Pharmacodynamie-Biochimique, UFR Biosciences, Université de Cocody- Abidjan, Côted’Ivoire. 22BP 1679 Abidjan. felhouph@yahoo.fr
authors: Félix Yapi
authors: FY
authors: Houphouët
authors: Adou
authors: A
authors: Yapo
authors: Yeo
authors: Y
authors: Dodehe
authors: Hugues
authors: H
authors: Ahiboh
authors: Jean David
authors: JD
authors: Nguessan
authors: Attoungré Marie-Laure
authors: AM
authors: Hauhouot
authors: Monnet
authors: M
authors: Dagui
authors: Joseph
authors: J
authors: Djaman Allico
mesh_terms: D000293:Adolescent; D015415:Biomarkers; D001798:Blood Proteins / Q000032:analysis*; D001827:Body Height; D001835:Body Weight; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D015362:Child Nutrition Disorders / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology*; D002675:Child, Preschool; D007560:Cote d'Ivoire / Q000453:epidemiology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007249:Inflammation / Q000097:blood / Q000209:etiology; D008297:Male; D012709:Serum Albumin / Q000032:analysis; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D001798:Blood Proteins; D007136:Immunoglobulins; D012709:Serum Albumin; D002097:C-Reactive Protein