title: The difference in location between traumatic cerebral microbleeds and microangiopathic microbleeds associated with stroke.
abstract: OBJECTIVE
  Microbleeds (MBs) are low-intensity spots on gradient echo T2*-weighted MRI frequently associated with cerebral microangiopathies resulting in stroke. MBs can also be caused by cerebral axonal injuries. We compared the location of MBs associated with cerebral microangiopathies with those associated with trauma.
  
  
  METHODS
  T2*-weighted MRI identified traumatic MBs (t-MBs) in 23 (6 females; 38.7 ± 25.8 years old) of the 312 patients with head trauma consecutively admitted to our hospital between March 2003 and March 2009. We prospectively examined for the presence of microangiopathic MBs (m-MBs) in the 131 patients (59 females; 65.2 ± 9.2 years old) admitted consecutively for stroke (May -December 2004) as controls.
  
  
  RESULTS
  We identified a total of 145 t-MBs and 504 m-MBs. t-MBs were frequently located in the mid portion of the subcortical area of the cerebrum, above the corpus callosum in axial slices, and were absent from the basal ganglia. In contrast, m-MBs were frequently located within the basal ganglia or thalamus.
  
  
  CONCLUSIONS
  There are substantial differences in locations of MB development in trauma patients in comparison to stroke patients.
authors: Department of Neurosurgery, Kushiro City General Hospital, Hokkaido, Japan. timaizum@d9.dion.ne.jp
authors: Toshio
authors: T
authors: Imaizumi
authors: Kei
authors: K
authors: Miyata
authors: Shigeru
authors: S
authors: Inamura
authors: Ikuhide
authors: I
authors: Kohama
authors: Kim Sang
authors: KS
authors: Nyon
authors: Tatsufumi
authors: T
authors: Nomura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology*; D002545:Brain Ischemia / Q000150:complications / Q000473:pathology*; D059345:Cerebral Small Vessel Diseases / Q000209:etiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D006259:Craniocerebral Trauma / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020521:Stroke / Q000150:complications / Q000473:pathology*