title: Preparation of fluoxetine by multiple flow processing steps.
abstract: Microflow technology is established as a modern and fashionable tool in synthetic organic chemistry, bringing great improvement and potential, on account of a series of advantages over flask methods. The study presented here focuses on the application of flow chemistry process in performing an efficient multiple step syntheses of (±)-fluoxetine as an alternative to conventional synthetic methods, and one of the few examples of total synthesis accomplished by flow technique.
authors: Eli Lilly and Co. Ltd., Lilly Research Centre, Erl Wood Manor, Windlesham, Surrey, UK.
authors: Batoul
authors: B
authors: Ahmed-Omer
authors: Adam J
authors: AJ
authors: Sanderson
mesh_terms: D002625:Chemistry, Organic / Q000295:instrumentation / Q000379:methods*; D005473:Fluoxetine / Q000138:chemical synthesis* / Q000737:chemistry; D006219:Halogens / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D006219:Halogens; D005473:Fluoxetine