title: HIV-infected women of Burkina Faso: a "reservoir" of mycoplasma infection.
abstract: BACKGROUND
  The objective of this work was to assess the prevalence of bacterial vaginosis (BV) and genital mycoplasma colonization in 251 HIV-positive compared to 200 HIV-negative women at the Maternal and Child Health (MCH) service of Saint Camille Medical Center  Ouagadougou (Burkina Faso).
  
  
  METHODS
  After revealing the cervix with a speculum, we collected swabs of vaginal discharge for the detection of pathogenic bacteria.
  
  
  RESULTS
  Among HIV-positive and HIV-negative women, we identified respectively: Mycoplasma hominis (16.7% versus 5.5%); Ureaplasma urealyticum (16.3% versus 0.0%); co-infection M. hominis with U. urealyticum (13.14% versus 0.0%); Candida albicans (21.11% versus 41.5%); E. coli (9.96% versus 4.0%); and the presence of abundant vaginal discharge (27.5% versus 5.0%) respectively. The Nugent's score, utilized for the diagnosis of BV, was significantly higher in HIV-positive women (p < 0.001) associated with poor vaginal hygiene practices (p < 0.01) and no use of condoms (p < 0.01). Enterobacter, Klebsiella pneumonia, Klebsiella oxitocica, Staphylococcus epidermidis and Staphylococcus aureus, Streptococcus agalactiae, Trichomonas vaginalis, and Gardnerella vaginalis were also isolated, but in a low prevalence ranging from 0% to 5%.
  
  
  CONCLUSIONS
  These results demonstrate that the HIV-positive women of Burkina Faso are frequently affected by BV and represent a reservoir for mycoplasma infection. Since these germs can lead to sterility and premature delivery, it is important to develop a policy of screening.
authors: Centre de Recherche Biomoléculaire Pietro Annigoni CERBA/LABIOGENE, Centre Medical St Camille, 01 BP 364 Ouagadougou 01, Burkina Faso.
authors: Florencia
authors: F
authors: Djigma
authors: Charlemagne
authors: C
authors: Ouedraogo
authors: Tani
authors: T
authors: Sagna
authors: Djeneba
authors: D
authors: Ouermi
authors: Korotini
authors: K
authors: Sanogo
authors: Cyrille
authors: C
authors: Bisseye
authors: Abdoulaye
authors: A
authors: Kabre
authors: Virginio
authors: V
authors: Pietra
authors: Jacques
authors: J
authors: Simpore
authors: Jean Baptiste
authors: JB
authors: Nikiema
authors: Salvatore
authors: S
authors: Musumeci
mesh_terms: D000328:Adult; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002050:Burkina Faso / Q000453:epidemiology; D002176:Candida albicans / Q000302:isolation & purification; D015897:Comorbidity; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000453:epidemiology*; D015995:Prevalence; D014246:Trichomonas vaginalis / Q000302:isolation & purification; D016585:Vaginosis, Bacterial / Q000453:epidemiology*