title: Defining reactivity: how several methodological decisions can affect conclusions about emotional reactivity in psychopathology.
abstract: There are many important methodological decisions that need to be made when examining emotional reactivity in psychopathology. In the present study, we examined the effects of two such decisions in an investigation of emotional reactivity in depression: (1) which (if any) comparison condition to employ; and (2) how to define change. Depressed (N = 69) and control (N = 37) participants viewed emotion-inducing film clips while subjective and facial responses were measured. Emotional reactivity was defined using no comparison condition (i.e., raw scores), baseline comparison condition (i.e., no stimulus presented), and neutral comparison condition (i.e., neutral stimulus presented). Change in emotional reactivity was assessed using four analytic approaches: difference scores, percentage change, residualised change, and ANCOVA. Results differed among the three comparison conditions and among several of the analytic approaches. Overall, our investigation suggests that choosing a comparison condition and the definition of change can significantly influence the presence of group differences in emotional reactivity. Recommendations for studies of emotional reactivity in psychopathology are discussed.
authors: Psychology Department, University of Illinois, Chicago, IL 60607, USA.
authors: Brady D
authors: BD
authors: Nelson
authors: Stewart A
authors: SA
authors: Shankman
authors: Thomas M
authors: TM
authors: Olino
authors: Daniel N
authors: DN
authors: Klein
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003627:Data Interpretation, Statistical; D003865:Major Depressive Disorder / Q000523:psychology*; D004644:Emotions; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D012107:Research Design / Q000706:statistics & numerical data*