title: Stereoselective synthesis of both enantiomers of rugulactone.
abstract: The stereoselective total synthesis of both enantiomers of rugulactone 1 has been completed by applying enantioselective allyl additions as key steps. Two different strategies based on highly stable and enantiomerically pure α-substituted allylboronic esters 2 and 3 were performed starting from boronic ester 4.
authors: Institut für Bioorganische Chemie der Heinrich-Heine-Universität Düsseldorf, Forschungszentrum Jülich, Stetternicher Forst, Geb. 15.8, 52426 Jülich, Germany.
authors: Dietrich
authors: D
authors: Böse
authors: Enrique
authors: E
authors: Fernández
authors: Jörg
authors: J
authors: Pietruszka
mesh_terms: D001897:Boronic Acids / Q000737:chemistry; D004952:Esters; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D001897:Boronic Acids; D004952:Esters; D007783:Lactones; C548571:rugulactone