title: Survival outcomes in surgical treatment of 72 cases of squamous cell carcinoma of the temporal bone.
abstract: OBJECTIVE
  To evaluate surgical outcomes for squamous cell carcinoma of the temporal bone.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Eye and ENT Hospital.
  
  
  METHODS
  Seventy-two patients with squamous cell carcinoma of the temporal bone were analyzed for survival. The patients were staged according to the modified Pittsburgh staging system. Five patients with T1 cancers underwent local resection (LR), and 10 patients with T1 cancers underwent lateral temporal bone resection (LTBR). Two patients with T2 cancers underwent LR, and 1 patient with T2 cancer underwent LTBR. One patient with T3 cancer underwent LR, 8 patients with T3 cancers underwent LTBR, and 10 patients with T3 cancers underwent subtotal temporal bone resection (STBR). Ten patients with T4 cancers underwent LTBR, and 25 patients with T4 cancers underwent STBR.
  
  
  RESULTS
  Of all patients that underwent surgery, 18 died of their disease during the follow-up time. The 5-year survival rates of patients with T stages 1 through 4 were 100%, 67%, 21%, and 14%, respectively. There was no statistically significant difference in 5-year survival rate between T3 and T4 using the log-rank test (p > 0.05). The 5-year survival rates after LTBR and STBR for T3 were 26% and 16% (p > 0.05), respectively, and those for T4 were 17% and 11% (p > 0.05), respectively.
  
  
  CONCLUSIONS
  An en bloc resection is favored in an effort to produce negative surgical margins for squamous cell carcinoma of the temporal bone. Adjunctive radiotherapy is used for advanced lesions.
authors: Department of Otology and Skull Base Surgery, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China. chifanglu@gmail.com
authors: Fang-Lu
authors: FL
authors: Chi
authors: Feng-Ming
authors: FM
authors: Gu
authors: Chun-Fu
authors: CF
authors: Dai
authors: Bing
authors: B
authors: Chen
authors: Hua-Wei
authors: HW
authors: Li
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D015996:Survival Rate; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome