title: Leiomyoma cutis: a clinicopathological series of 37 cases.
abstract: BACKGROUND
  Cutaneous leiomyomas are benign smooth muscle tumors that comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma.
  
  
  OBJECTIVE
  The objective of this study was to report a series of cases seen in last 8 years in a tertiary care hospital in north India and to discuss their clinicopathologic findings.
  
  
  METHODS
  Paraffin-embedded blocks of cases reported as cutaneous leiomyoma from 1999 to 2007 were retrieved from the Institute of Pathology, New Delhi, and their clinical parameters were noted. Their histopathological features were reviewed on hematoxylin-eosin stained slides. Immunohistochemistry was performed where necessary.
  
  
  RESULTS
  Twenty-seven cases of piloleiomyoma, three cases of angioleiomyoma, five breast leiomyomas, and two scrotal leiomyomas were seen in patients ranging from 21 to 65 years of age, with an average of 38.2 years at presentation. There was a male predominance with 26 males and 11 females (M:F = 2.2:1). Solitary lesions (n = 21) were more common than multiple ( n = 16). The trunk and upper limbs were involved most commonly, comprising 23 of 37 (62.2%) cases. This was followed by lower limb, face, breast, and scrotum.
  
  
  CONCLUSIONS
  Cutaneous leiomyomas are rare lesions and form an important clinical differential diagnosis of painful papulonodules. These must be biopsied in order to differentiate them from other spindle cell lesions.
authors: Institute of Pathology, ICMR, Safdarjung Hospital Campus, New Delhi, India.
authors: Purnima
authors: P
authors: Malhotra
authors: Harpreet
authors: H
authors: Walia
authors: Avninder
authors: A
authors: Singh
authors: V
authors: V
authors: Ramesh