title: Three-component synthesis of cyclic enaminones via ketene cyclization.
abstract: Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.
authors: Department of Chemistry, Institute for Therapeutics Discovery and Development, College of Pharmacy, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States.
authors: Hajime
authors: H
authors: Seki
authors: Gunda I
authors: GI
authors: Georg
mesh_terms: D001391:Azo Compounds / Q000737:chemistry; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001391:Azo Compounds; D005030:Ethylenes; D007659:Ketones; C008223:ketene