title: Uncommon Neosartorya udagawae fungus as a causative agent of severe corneal infection.
abstract: We report the first documented case of a posttraumatic fungal keratitis caused by Neosartorya udagawae. The patient was empirically treated with fluconazole until a corneal scraping grew an Aspergillus fumigatus-like fungus, and itraconazole therapy was then established. A sequence-based approach assigned the isolate to the species. Five months after completion of antifungal therapy, endophthalmitis occurred and orbital exenteration was necessary.
authors: Institute of Microbiology, Universita` Cattolica del Sacro Cuore, Rome, Italy.
authors: Brunella
authors: B
authors: Posteraro
authors: Romano
authors: R
authors: Mattei
authors: Fausto
authors: F
authors: Trivella
authors: Andrea
authors: A
authors: Maffei
authors: Antonio
authors: A
authors: Torre
authors: Elena
authors: E
authors: De Carolis
authors: Patrizia
authors: P
authors: Posteraro
authors: Giovanni
authors: G
authors: Fadda
authors: Maurizio
authors: M
authors: Sanguinetti
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D003316:Corneal Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology* / Q000601:surgery; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D003646:Debridement; D015725:Fluconazole / Q000008:administration & dosage; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D008826:Microbial Sensitivity Tests; D008853:Microscopy; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D055326:Neosartorya / Q000302:isolation & purification*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D014947:Wounds and Injuries / Q000150:complications*
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D017964:Itraconazole; D015725:Fluconazole