title: The influence of gender on mortality in patients after thoracic endovascular aortic repair.
abstract: OBJECTIVE
  The aim of this study was to determine if gender affects mortality in patients after thoracic endovascular aortic repair (TEVAR).
  
  
  METHODS
  We retrospectively analyzed 286 consecutive patients undergoing TEVAR at our institution during a 12-year period (female 29%, median age 69 years). Chronic health conditions, risk factors, as well as early and long-term outcome were assessed. Follow-up data were available in all patients.
  
  
  RESULTS
  For female gender, 1-year survival and 5-year survival was 84% and 56% versus 83% and 60% for male gender. No significant gender influence was observed (odds ratio (OR) 0.96, 95% confidence interval (CI) 0.59-1.56). Furthermore, no significant gender influence could be observed according to the individual indication--atherosclerotic aneurysms (OR 0.78 95%CI 0.41-1.47), acute type B dissections (OR 0.78 95%CI 0.21-2.83), penetrating atherosclerotic ulcers/intramural hematoma (OR 1.48 95%CI 0.53-4.19), and traumatic aortic lesions (OR 1.48 95%CI 0.53-4.19). Age (OR 3.6 95%CI 1.24-10.45) and chronic obstructive pulmonary disease (COPD; OR 3.09 95%CI 0.98-9.73) were independent predictors of mortality in females.
  
  
  CONCLUSIONS
  Gender does not affect mortality in patients after TEVAR irrespective of the underlying indication, atherosclerotic aneurysms, acute type B dissections, penetrating ulcers/intramural hematoma, and traumatic aortic lesions. Classical risk factors such as age and the presence of COPD at the time of TEVAR remain the most important risk factors in females.
authors: Department of Cardiovascular Surgery, University Hospital Berne, Berne, Switzerland.
authors: Martin
authors: M
authors: Czerny
authors: Michael
authors: M
authors: Hoebartner
authors: Gottfried
authors: G
authors: Sodeck
authors: Martin
authors: M
authors: Funovics
authors: Andrzej
authors: A
authors: Juraszek
authors: Tomasz
authors: T
authors: Dziodzio
authors: Michael
authors: M
authors: Grimm
authors: Marek
authors: M
authors: Ehrlich
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic / Q000293:injuries / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery; D001018:Aortic Diseases / Q000601:surgery*; D050197:Atherosclerosis / Q000601:surgery; D019917:Blood Vessel Prosthesis Implantation; D002908:Chronic Disease; D004812:Epidemiologic Methods; D005260:Female; D006406:Hematoma / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation / Q000706:statistics & numerical data; D012737:Sex Factors; D016896:Treatment Outcome