title: Ablation of ventricular fibrillation in an orthotopic heart lung transplant.
abstract: Arrhythmia is well described following cardiac transplantation. We report a case of recurrent ventricular fibrillation (VF) originating from an orthotopic cardiac allograft. VF was consistently initiated on each occasion by a relatively early-coupled monomorphic ventricular ectopic. Antiarrhythmic agents failed to suppress the arrhythmia. Electrophysiological testing with noncontact mapping showed a high-frequency potential at the earliest activation site. Radiofrequency ablation resulted in abolition of ventricular ectopy with no further VF recurrence. Although there is substantial experience with ablation of atrial tachycardias in this setting, experience with ablation for ventricular arrhythmias is limited and ablation of VF not described.
authors: Cardiology Department, Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, London, UK. j.lyne@rbht.nhs.uk
authors: Jonathan
authors: J
authors: Lyne
authors: Tom
authors: T
authors: Wong
authors: Nicholas
authors: N
authors: Banner
authors: Vias
authors: V
authors: Markides
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D017115:Catheter Ablation; D004568:Electrodiagnosis; D005260:Female; D016041:Heart-Lung Transplantation / Q000009:adverse effects*; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D018879:Ventricular Premature Complexes / Q000175:diagnosis / Q000601:surgery
chemical_list: D000889:Anti-Arrhythmia Agents