title: Larvicidal activity of some secondary lichen metabolites against the mosquito Culiseta longiareolata Macquart (Diptera: Culicidae).
abstract: The larvicidal activity of some lichen metabolites, (+)-usnic acid, atranorin, 3-hydroxyphysodic acid and gyrophoric acid, against the second and third instar larvae of the mosquito Culiseta longiareolata were studied. All metabolites caused high larvicidal activities. When metabolites were compared on the basis of their LC(50) values, the order of increasing toxicity was as follows: gyrophoric acid (0.41 ppm) > (+)-usnic acid (0.48 ppm) > atranorin (0.52 ppm) > 3-hydroxyphysodic acid (0.97 ppm). However, when LC(90) values were compared, the order of toxicity was (+)-usnic acid (1.54 ppm) > gyrophoric acid (1.93 ppm) > 3-hydroxyphysodic acid (4.33 ppm) > atranorin (5.63 ppm). In conclusion, our results found that lichen secondary metabolites may have a promising role as potential larvicides.
authors: Department of Biology, Faculty of Arts and Science, Akdeniz University, Antalya, Turkey.
authors: H
authors: H
authors: Cetin
authors: O
authors: O
authors: Tufan-Cetin
authors: A O
authors: AO
authors: Turk
authors: T
authors: T
authors: Tay
authors: M
authors: M
authors: Candan
authors: A
authors: A
authors: Yanikoglu
authors: H
authors: H
authors: Sumbul
mesh_terms: D000818:Animals; D001565:Benzoates / Q000494:pharmacology; D001572:Benzofurans / Q000494:pharmacology; D009033:Culicidae / Q000187:drug effects*; D003990:Dibenzoxepins / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000494:pharmacology; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D008011:Lichens / Q000737:chemistry* / Q000378:metabolism; D015394:Molecular Structure
chemical_list: C501217:3-hydroxyphysodic acid; D001565:Benzoates; D001572:Benzofurans; D003990:Dibenzoxepins; D062385:Hydroxybenzoates; D007306:Insecticides; C073339:usnic acid; C026304:atranorin; C120727:gyrophoric acid