title: Can food allergy be prevented? The current evidence.
abstract: Food allergy is a recognized public health concern, for which preventative strategies are required. Although an intervention that adequately protects against the development of food allergy has still to be identified, limited benefits have been shown for the prevention of related allergic conditions such as eczema, and to a lesser extent asthma and rhinitis; these benefits are usually limited to at-risk populations. Prevention strategies need to be tested using randomized controlled study designs that account for the numerous methodological challenges, safety concerns, and necessary ethical limitations.
authors: Division of Asthma, Allergy and Lung Biology, Guy's and St Thomas' National Health Service Foundation Trust, Medical Research Council, London, UK. george.dutoit@kcl.ac.uk
authors: George
authors: G
authors: Du Toit
authors: Gideon
authors: G
authors: Lack
mesh_terms: D001249:Asthma / Q000276:immunology / Q000517:prevention & control; D001942:Breast Feeding; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions / Q000276:immunology; D019587:Dietary Supplements; D004485:Eczema / Q000276:immunology / Q000517:prevention & control; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007108:Immune Tolerance; D007073:Immunoglobulin E / Q000276:immunology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D016269:Milk Hypersensitivity / Q000517:prevention & control; D009751:Nutritional Requirements; D056692:Prebiotics; D011247:Pregnancy; D019936:Probiotics; D016032:Randomized Controlled Trials as Topic; D012220:Rhinitis / Q000276:immunology / Q000517:prevention & control
chemical_list: D056692:Prebiotics; D007073:Immunoglobulin E