title: A multicenter survey of heparin prophylaxis practice in pediatric critical care.
abstract: Heparin prophylaxis (HP) is commonly used for prevention of central venous catheter (CVC)-related complications among pediatric intensivists, yet efficacy of this therapy is unknown. We conducted a survey of pediatric intensivists and their experiences with HP. A total of 96 responses were received. Almost half of the respondents regularly used HP in patients with CVCs, yet most were unsure of its benefit. The majority of respondents claimed to experience no adverse effects; the complications that were reported to occur were related to bleeding or suspected heparin-induced thrombocytopenia (HIT). Overall, participants felt CVC-associated HP was safe in pediatric critical illness, while acknowledging the paucity of compelling data.
authors: Department of Pediatrics, Section of Critical Care, The Children's Hospital of Aurora, University of Colorado School of Medicine, Aurora, CO, USA.
authors: Margaret
authors: M
authors: Clarke
authors: Department of Pediatrics, Section of Cardiology, The Children's Hospital of Aurora, University of Colorado School of Medicine; Aurora, CO, USA.
authors: Eduardo
authors: E
authors: da Cruz
authors: Department of Pediatrics, Section of Cardiology, The Children's Hospital of Aurora, University of Colorado School of Medicine; Aurora, CO, USA.
authors: Julianne
authors: J
authors: Koehler
authors: Department of Pediatrics, Section of Cardiology, The Children's Hospital of Aurora, University of Colorado School of Medicine; Aurora, CO, USA kaufman.jonathan@tchden.org.
authors: Jon
authors: J
authors: Kaufman
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001291:Attitude of Health Personnel; D061807:Catheter Obstruction / Q000209:etiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000379:methods; D018890:Chemoprevention / Q000706:statistics & numerical data; D002648:Child; D003422:Critical Care / Q000379:methods*; D019538:Health Care Surveys; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D010372:Pediatrics / Q000379:methods; D013927:Thrombosis / Q000150:complications / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D006493:Heparin