title: [Rare congenital heart disease as a cause of tuberculosis activation].
abstract: BACKGROUND
  Patients with congenital cyanotic heart defects and the left-to-right shunt are at a three times higher risk of getting tuberculosis than acyanotic ones. No TB cases have been recorded in adult patients with the right-to-left shunt having cyanosis since their birth.
  
  
  METHODS
  A 34-year-old man was referred to our Clinic with the discomforts such as chronic cough, hemoptysis and insomnia. At the admission he was pale, cyanotic, with a partial manifest respiratory insufficiency and characteristic TB pulmonary lesions detected by x-rays and tomography. After the sputum positive TB recidivism had been diagnosed, the antituberculotics treatment was introduced resulting in the successful smear and culture conversion and radiological regression of pulmonary lesions, but associated with non-explicable deterioration of cyanosis and chronic respiratory insufficiency until Doppler-echocardiographic examination verified the presence of tetralogy of Fallot.
  
  
  CONCLUSIONS
  Congenital cyanotic heart defects are extremely rare in adults. Nevertheless, it is necessary to maintain a very high level of clinical suspicion regarding TB activation even in the cases of defects with the right-to-left shunt.
authors: Klinika za plućne bolesti i tuberkulozu, Knez Selo, Klinicki centar Nis, Nis. mradovic@bankerinter.net
authors: Milan
authors: M
authors: Radović
authors: Lidija
authors: L
authors: Ristić
authors: Ivana
authors: I
authors: Stanković
authors: Dejan
authors: D
authors: Petrović
mesh_terms: D000328:Adult; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D008297:Male; D012307:Risk Factors; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*