title: Gender aspects of osteoporosis and bone strength.
abstract: Although postmenopausal and elderly women are more frequently affected by osteoporosis, men are not protected from the disease. Age-related osteoporosis involves several gender-specific clinical aspects such as disease onset time and different dynamics of bone loss. Men benefit from larger bones and a time-delay of age-related changes in bone density and quality. Moreover, secondary osteoporosis is more common in males than in females. High-resolution peripheral quantitative computed tomography (HR-pQCT) and high-resolution magnetic resonance imaging (HR-MRI) represent novel research tools for a noninvasive quantification of bone microstructure which is of interest for musculoskeletal gender studies. For optimal design of such studies, researchers should be aware of technical pitfalls and site-specificity of bone microstructure.
authors: Department of Radiology, Medical University of Vienna, Vienna, Austria. janina.patsch@meduniwien.ac.at
authors: Janina M
authors: JM
authors: Patsch
authors: Julia
authors: J
authors: Deutschmann
authors: Peter
authors: P
authors: Pietschmann
mesh_terms: D000367:Age Factors; D000368:Aged; D001317:Austria; D015519:Bone Density / Q000502:physiology; D001842:Bone and Bones / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D010024:Osteoporosis / Q000175:diagnosis* / Q000503:physiopathology; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis* / Q000503:physiopathology; D058866:Osteoporotic Fractures / Q000175:diagnosis / Q000503:physiopathology; D011944:Receptors, Androgen / Q000502:physiology; D011960:Receptors, Estrogen / Q000502:physiology; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D011944:Receptors, Androgen; D011960:Receptors, Estrogen