title: [Standardized x-ray reports of the spine in osteogenesis imperfecta].
abstract: OBJECTIVE
  In this study we present a standard for radiological reports in patients with osteogenesis imperfecta (OI). The parameters can be used to describe X-rays of the lateral spine and give an impartial description of anatomical structures during a treatment with bisphosphonates.
  
  
  METHODS
  In this retrospective analysis we included 48 patients with OI (31 female, 17 male [1.5 months - 19 years, mean age 9.0 years]). Lateral spine X-rays were analyzed by 2 radiologists before and during treatment. The parameters of the standardized report are degree of kyphoscoliosis, compression of single vertebrae, predominant type of vertebral deformities and extent of vertebral compression (score 1 - 5).
  
  
  RESULTS
  There was no clear trend in the change of compression of single vertebrae. Some vertebrae with ventral compression showed an upgrowth to vertebrae with harmonic compression. Other deformities showed only marginal changes. In 26 patients the kyphoscoliosis improved (mean 10 degrees), in 36 patients the thoracic vertebrae compression increased and in 30 patients the vertebral height in the lumbar spine increased. The improvement of vertebral height was 1 point in the thoracic and lumbar spine.
  
  
  CONCLUSIONS
  We propose a standardized report of X-rays of the lateral spine in patients with OI with quantitative and semiquantitative parameters using morphological criteria. These include compression of single vertebrae, degree of kyphoscoliosis, vertebral deformities and the severity of vertebral compression in the thoracic and lumbar spine.
authors: Institut und Poliklinik für Radiologische Diagnostik, Kinderradiologie, Uniklinik Köln. friederike.koerber@uk-koeln.de
authors: F
authors: F
authors: Koerber
authors: O
authors: O
authors: Semler
authors: A W
authors: AW
authors: Demant
authors: S
authors: S
authors: Koerber
authors: E
authors: E
authors: Schönau
authors: K-J
authors: KJ
authors: Lackner
mesh_terms: D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D007738:Kyphosis / Q000000981:diagnostic imaging*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008297:Male; D010013:Osteogenesis Imperfecta / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011859:Radiography; D012600:Scoliosis / Q000000981:diagnostic imaging*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging*
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates