title: Update on pathogenesis and diagnosis of intravascular catheter-related infections.
abstract: Infections associated with the use of intravascular catheters cause a substantial morbidity and mortality. New knowledge in the pathogenesis of catheter related bloodstream infections has led to advances in the prevention and management of these infections. The purpose of the present chapter is to review the most relevant data published recently on pathogenesis and diagnosis of intravascular catheter-related infections. It is focus in four different aspects: a) pathogenesis of catheter-related infections and particularly factors affecting biofilm formation and modulation; b) pathogenesis of intravascular catheter-related infections caused by Staphylococcus lugdunensis; c) news on microbiological diagnosis of catheter-related bacteremia; and d) evaluation of current use of blood cultures in the era of continuous monitoring blood cultures systems.
authors: Departamento de Microbiología, Hospital Universitario Virgen Macarena, Facultad de Medicina, Sevilla, Spain. apascual@us.es
authors: Alvaro
authors: A
authors: Pascual
authors: Emilia
authors: E
authors: Cercenado
authors: Miguel
authors: M
authors: Salavert
authors: José
authors: J
authors: Elías García-Sánchez
authors: José María
authors: JM
authors: Eiros
authors: Josefina
authors: J
authors: Liñares
authors: Cristina
authors: C
authors: Fernández
authors: Jordi
authors: J
authors: Vila
mesh_terms: D016470:Bacteremia / Q000175:diagnosis / Q000209:etiology; D001769:Blood / Q000382:microbiology; D055499:Catheter-Related Infections / Q000175:diagnosis / Q000209:etiology; D003422:Critical Care; D006801:Humans; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology