title: Total aortic replacement in Loeys-Dietz syndrome.
abstract: Loeys-Dietz syndrome (LDS) is a recently identified genetic complex characterized in part by rapidly progressive aortic and branch vessel disease. We now describe total aortic replacement using an open Extent II thoracoabdominal repair followed by second-stage redo-sternotomy for a valve-sparing aortic root replacement and hybrid aortic arch repair in a patient with this syndrome.
authors: Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
authors: Judson B
authors: JB
authors: Williams
authors: Richard L
authors: RL
authors: McCann
authors: G Chad
authors: GC
authors: Hughes
mesh_terms: D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D003937:Diagnosis, Differential; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D055947:Loeys-Dietz Syndrome / Q000000981:diagnostic imaging / Q000601:surgery*; D016343:Monitoring, Intraoperative; D011474:Prosthesis Design; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult