title: [Myocardial performance index: prediction and monitoring of remodeling and functioning of the left ventricle after first myocardial infarction].
abstract: BACKGROUND
  Dynamic changing of left ventricular geometry and contractile state after acute myocardial infarction is responsible for various aspects of left ventricular remodeling and dysfunction. A number of studies have shown that myocardial performance index allows prediction of acute myocardial infarction complications. The objective of our study was to determine the power of myocardial performance index to predict and assess the severity of left ventricular remodeling, systolic and diastolic dysfunction after acute myocardial infarction over the long term.
  
  
  METHODS
  Echocardiography was performed within the first week of hospitalization, after one, three and six months in 77 patients with first acute myocardial infarction. At the end of the study the patients were divided into group A and B with mild and severe left ventricular remodeling, respectively.
  
  
  RESULTS
  Myocardial performance index was significantly lower in group A compared to B, at the beginning (0.62 vs. 0.75; p = 0.002), and at the end of study (0, 60 vs. 0, 69; p = 0.004). After six months, 31% of study patients developed LV systolic dysfunction with prevalence in group B (56% vs. 19%, p = 0.002). Myocardial performance index > or = 0.70 at first week after acute myocardial infarction is a strong predictive parameter for extensive early and late left ventricular remodeling and systolic dysfunction (p < 0.05), but it is not a valuable predictor of diastolic failure.
  
  
  CONCLUSIONS
  MPI obtained at first week of acute myocardial infarction was predictive for early and long term left ventricular remodeling and systolic dysfunction. Myocardial performance index had doubtful clinical use in assessing dynamics of remodeling and it was without clinical value in predicting diastolic function deterioration.
authors: Univerzitetski klinitki centar Dr Dragisa Misović, Beograd.
authors: Vera
authors: V
authors: Celić
authors: Milica
authors: M
authors: Dekleva
authors: Anka
authors: A
authors: Majstorović
authors: Nenad
authors: N
authors: Radivojević
authors: Nada
authors: N
authors: Kostić
authors: Zorica
authors: Z
authors: Caparević
mesh_terms: D000328:Adult; D000368:Aged; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016277:Ventricular Function, Left; D020257:Ventricular Remodeling