title: Protein-based multi-bit biomemory device consisting of various metalloproteins on self-assembled 11-MUA layer.
abstract: A multi-bit biomemory device was devised by introducing 4 different metalloproteins (azurin, cytochrome c, ferredoxin, myoglobin) to an electronic device using 11-MUA (11-mercapto-undecanoic acid) as the chemical linker. The immobilization of the 4 different self-assembled protein layers on a Au substrate via 11-MUA were confirmed by Raman spectroscopy and atomic force microscopy (AFM). The redox properties of these 4 different protein layers immobilized onto Au surface were assessed by cyclic voltammetry (CV). In addition, their memory functions were verified by chronoamperometry (CA). Based on these results, we demonstrated that a multi-bit biomemory concept could be realized using various metalloproteins as active materials.
authors: Department of Chemical and Biomolecular Engineering, Sogang University, #1 Shinsu-dong, Mapo-gu, Seoul 121-742, Republic of Korea.
authors: Taek
authors: T
authors: Lee
authors: Junhong
authors: J
authors: Min
authors: Jin-Ho
authors: JH
authors: Lee
authors: Jeong-Woo
authors: JW
authors: Choi
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry; D015374:Biosensing Techniques / Q000379:methods; D005227:Fatty Acids / Q000737:chemistry*; D005656:Fungal Proteins / Q000737:chemistry; D008667:Metalloproteins / Q000737:chemistry*; D046228:Microarray Analysis / Q000379:methods*; D018625:Microscopy, Atomic Force; D049329:Nanostructures / Q000737:chemistry / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods*; D013059:Spectrum Analysis, Raman; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: C505222:11-mercaptoundecanoic acid; D001426:Bacterial Proteins; D005227:Fatty Acids; D005656:Fungal Proteins; D008667:Metalloproteins; D013438:Sulfhydryl Compounds