title: High doses alprazolam induced amenorrhoea and galactorrhoea.
abstract: Alprazolam belongs in the group of anxiolytics, medicaments used for reducing anxiety. As most other drugs, it can cause various adverse events, including hormonal disturbances and imbalance. Prolactin elevation is one such hormonal adverse event that can lead to galactorrhoea, or abnormal milk discharge from the breast and amenorrhoea. In this case report we will present the case of a female patient that developed galactorrhoea while treated with alprazolam, after all physical factors that can also cause these symptoms were excluded.
authors: Psychiatric Clinic of University Hospital Centre Rijeka, Cambierieva 17/7, 51000 Rijeka, Croatia. daniela.petric1@ri.t-com.hr
authors: Daniela
authors: D
authors: Petrić
authors: Marija Vučić
authors: MV
authors: Peitl
authors: Vjekoslav
authors: V
authors: Peitl
mesh_terms: D000328:Adult; D000525:Alprazolam / Q000008:administration & dosage / Q000009:adverse effects*; D000568:Amenorrhea / Q000139:chemically induced*; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D005260:Female; D005687:Galactorrhea / Q000139:chemically induced*; D006801:Humans; D012651:Self Medication; D013001:Somatoform Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology
chemical_list: D014151:Anti-Anxiety Agents; D003692:Delayed-Action Preparations; D000525:Alprazolam