title: Copy number variations in affective disorders and meta-analysis.
abstract: In two recent studies 10 copy number variants (CNV) were found to be overrepresented either among patients suffering from affective disorders in an Amish family or in the Wellcome Trust Case-Control Consortium study. Here, we investigate if these variants are associated with affective disorders in a combined analysis of three case-control samples from Denmark, Norway and Iceland. A total of 1897 cases (n=1223 unipolar and n=463 bipolar) and 11 231 controls were analyzed for CNVs at the 10 genomic loci, but we found no combined association between these CNVs and affective disorders.
authors: Institute for Biological Psychiatry, Mental Health Centre Sct. Hans, Roskilde, Norway.
authors: Line
authors: L
authors: Olsen
authors: Thomas
authors: T
authors: Hansen
authors: Srdjan
authors: S
authors: Djurovic
authors: Eva
authors: E
authors: Haastrup
authors: Anders
authors: A
authors: Albrecthsen
authors: Louise K E
authors: LK
authors: Hoeffding
authors: Anna
authors: A
authors: Secher
authors: Omar
authors: O
authors: Gustafsson
authors: Klaus D
authors: KD
authors: Jakobsen
authors: Finn C
authors: FC
authors: Nielsen
authors: Henrik
authors: H
authors: Ullum
authors: Gunnar
authors: G
authors: Morken
authors: Ingrid
authors: I
authors: Agartz
authors: Ingrid
authors: I
authors: Melle
authors: Ulrik
authors: U
authors: Gether
authors: Ole A
authors: OA
authors: Andreassen
authors: Thomas
authors: T
authors: Werge
mesh_terms: D001714:Bipolar Disorder / Q000235:genetics; D016022:Case-Control Studies; D056915:DNA Copy Number Variations / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D019964:Mood Disorders / Q000235:genetics*; D012537:Scandinavian and Nordic Countries