title: Chlamydophila pneumoniae infection among Basic Underwater Demolition/SEAL (BUD/S) candidates, Coronado, California, July 2008.
abstract: Community-acquired pneumonia can compromise readiness of recruits and service members operating in confined spaces. Often respiratory pathogens are implicated in outbreaks. In July 2008, 5 Basic Underwater Demolition/SEAL students entering an intense period of training at Naval Amphibious Base Coronado reported with clinical symptoms and chest radiographs consistent with pneumonia. Throat and nasal swabs were tested for respiratory pathogens. Molecular evidence indicated that they were infected with the atypical bacterium Chlamydophila pneumoniae. Thirty contemporaneous Basic Underwater Demolition/SEAL students were tested to determine the extent of C pneumoniae infection burden. Five additional cases were captured within this group. The 10 individuals diagnosed with C pneumoniae were treated with a course of azithromycin, Avelox (moxifloxacin hydrochloride), and doxycycline. The cases ended following the isolation of cases and prophylaxis with oral antibiotics. This work highlights the importance of rapid respiratory disease diagnoses to guide the clinical response following the emergence of respiratory infections among military trainees.
authors: Department of Respiratory Diseases Research, Naval Health Research Center, San Diego, CA 92106, USA.
authors: Robert G
authors: RG
authors: Coon
authors: Melinda S
authors: MS
authors: Balansay
authors: Dennis J
authors: DJ
authors: Faix
authors: Anthony W
authors: AW
authors: Hawksworth
authors: Matthew B
authors: MB
authors: Patterson
authors: Patrick J
authors: PJ
authors: Blair
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017963:Azithromycin / Q000008:administration & dosage; D002140:California / Q000453:epidemiology; D023521:Chlamydophila Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D016993:Chlamydophila pneumoniae; D004196:Disease Outbreaks / Q000706:statistics & numerical data; D004359:Drug Therapy, Combination; D004587:Electrophoresis, Agar Gel; D006801:Humans; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D016133:Polymerase Chain Reaction
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin