title: Preparation and characterization of poly(vinyl alcohol)/poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone)/nano-hydroxyapatite composite membranes for tissue engineering.
abstract: In this paper, the poly(vinyl alcohol)/poly(epsilon-caprolactone)-PEG-poly(epsilon-caprolactone)/nano-hydroxyapatite (PVA/PCEC/n-HA) composite membranes were prepared by solution casting and evaporation methods. The effect of n-HA content on the properties of the composite membranes was studied. The PVA/PCEC/n-HA composite membranes were analyzed by FTIR spectroscopy, X-ray diffraction, water content measurement, contact angle, mechanical test, scanning electron microscopy. The results showed that the surface roughness of the composite membranes increased with the increase of n-HA contents. The n-HA content had obvious influence on the swelling ratio, tensile strength and elongation rate of the composite membranes. With the increase of n-HA contents, the swelling ratio increased at first, and then decreased; tensile strength and elongation rate decreased gradually. The PVA/PCEC/n-HA composite membranes may be applied in the field of tissue engineering.
authors: State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Jinrong
authors: J
authors: Peng
authors: Xiaolu
authors: X
authors: Li
authors: Gang
authors: G
authors: Guo
authors: Tingqiang
authors: T
authors: Yi
authors: Shaozhi
authors: S
authors: Fu
authors: Hang
authors: H
authors: Liang
authors: Feng
authors: F
authors: Luo
authors: Xia
authors: X
authors: Zhao
authors: Yuquan
authors: Y
authors: Wei
authors: Zhiyong
authors: Z
authors: Qian
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis*; D017886:Durapatite / Q000737:chemistry*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008422:Materials Testing; D008567:Membranes, Artificial; D011091:Polyesters / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry*; D023822:Tissue Engineering / Q000295:instrumentation*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials; C519734:Kollicoat IR; D008567:Membranes, Artificial; D011091:Polyesters; D011145:Polyvinyls; C515340:poly(epsilon-caprolactone)-b-poly(ethyleneglycol)-b-poly(epsilon-caprolactone); D011092:Polyethylene Glycols; D017886:Durapatite