title: Recurrent intussusception in infants.
abstract: OBJECTIVE
  Clinical features to identify infants at increased risk of recurrence after a primary episode of intussusception (IS) are poorly defined.
  
  
  METHODS
  Prospective study of the clinical presentation, treatment and outcome in infants <2 years presenting with acute IS to the National Hospital of Pediatrics, Hanoi, over a 14-month period (1 November 2002 to 31 December 2003). A retrospective review of medical records was performed to verify complete patient ascertainment.
  
  
  RESULTS
  Five hundred ninety-eight children were recruited, including 513 (86%) with a primary episode only and 53 (9%) with ≥1 recurrent episodes. Another 32 (5%) infants presented with recurrent IS, but the primary episode of IS occurred outside the study period. Estimated recurrence risk at 6 months following a primary episode was 14%. A pathological lead point was rare in primary (n= 1) and recurrent IS (n= 1). Most infants were successfully treated with enema reduction.
  
  
  CONCLUSIONS
  This study describes the natural history of recurrent IS in infants and may assist in interpreting data from post-marketing surveillance following introduction of rotavirus vaccines.
authors: Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia.
authors: Frances A
authors: FA
authors: Justice
authors: Liem T
authors: LT
authors: Nguyen
authors: Son N
authors: SN
authors: Tran
authors: Carl D
authors: CD
authors: Kirkwood
authors: Ngo Thi
authors: NT
authors: Thi
authors: John B
authors: JB
authors: Carlin
authors: Julie E
authors: JE
authors: Bines
mesh_terms: D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D007223:Infant; D007443:Intussusception / Q000453:epidemiology / Q000503:physiopathology* / Q000517:prevention & control; D008485:Medical Audit; D012008:Recurrence; D014744:Vietnam / Q000453:epidemiology