title: Short-range clinical, dynamic magnetic resonance imaging and P-QOL questionnaire results after mesh repair in female pelvic organ prolapse.
abstract: OBJECTIVE
  To evaluate clinical, quality-of-life (QoL) and dynamic magnetic resonance imaging (dMRI) results in patients with pelvic organ prolapse (POP) preoperatively, and 4 and 12 weeks after anterior and/or posterior mesh repair.
  
  
  METHODS
  Thirty-six patients (mean age 65 years) with symptomatic pelvic floor descent underwent mesh repair. The prolapse was quantified using the POP-Q system. Before surgery as well as 4 and 12 weeks after surgery, the pelvic organ positions were measured on dynamic magnetic resonance imaging during Valsalva manoeuvre in relation to the pubococcygeal and mid-pubic lines to assess surgery outcome. Patients also completed the P-QOL questionnaire to evaluate subjective changes at each visit.
  
  
  RESULTS
  Four and 12 weeks after surgery patients showed improvement of the POP on clinical examination and on dynamic MRI. The latter demonstrated high significance (p<0.001) especially in bladder and vaginal cuff/cervix positions during maximal straining. All quality-of-life domains and some symptom questions of the P-QOL questionnaire significantly improved (p<0.05) 12 weeks after surgery.
  
  
  CONCLUSIONS
  Significant anatomical and quality-of-life improvement was demonstrated after anterior and/or posterior mesh repair for POP using dynamic MRI and the P-QOL questionnaire.
authors: Department of Obstetrics and Gynecology, University of Heidelberg Medical School, Heidelberg, Germany. kerstin.brocker@med.uni-heidelberg.de
authors: Kerstin A
authors: KA
authors: Brocker
authors: Celine D
authors: CD
authors: Alt
authors: Caroline
authors: C
authors: Corteville
authors: Peter
authors: P
authors: Hallscheidt
authors: Florian
authors: F
authors: Lenz
authors: Christof
authors: C
authors: Sohn
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005858:Germany; D058869:Gynecological Examination; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D013526:Surgical Mesh / Q000009:adverse effects*; D011795:Surveys and Questionnaires; D014636:Valsalva Maneuver