title: Polyphasic identification and susceptibility to seven antifungals of 102 Aspergillus isolates recovered from immunocompromised hosts in Greece.
abstract: In this study, the first such study in Greece, we used polyphasic identification combined with antifungal susceptibility study to analyze Aspergillus clinical isolates comprising 102 common and rare members of sections Fumigati, Flavi, Terrei, Nidulantes, Nigri, Circumdati, Versicolores, and Usti. High amphotericin B MICs (>2 μg/ml) were found for 17.6% of strains. Itraconazole, posaconazole, and voriconazole MICs of >4 μg/ml were shown in 1%, 5%, and 0% of the isolates, respectively. Anidulafungin, micafungin, and caspofungin minimum effective concentrations (MECs) of ≥2 μg/ml were correspondingly recorded for 4%, 9%, and 33%, respectively, of the strains.
authors: Mycology Laboratory, Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, Goudi 11527, Athens, Greece. marabatz@med.uoa.gr
authors: Michael
authors: M
authors: Arabatzis
authors: Manousos
authors: M
authors: Kambouris
authors: Miltiades
authors: M
authors: Kyprianou
authors: Aikaterini
authors: A
authors: Chrysaki
authors: Maria
authors: M
authors: Foustoukou
authors: Maria
authors: M
authors: Kanellopoulou
authors: Lydia
authors: L
authors: Kondyli
authors: Georgia
authors: G
authors: Kouppari
authors: Chrysa
authors: C
authors: Koutsia-Karouzou
authors: Evangelia
authors: E
authors: Lebessi
authors: Anastasia
authors: A
authors: Pangalis
authors: Efthimia
authors: E
authors: Petinaki
authors: Ageliki
authors: A
authors: Stathi
authors: Eleftheria
authors: E
authors: Trikka-Graphakos
authors: Erriketi
authors: E
authors: Vartzioti
authors: Aliki
authors: A
authors: Vogiatzi
authors: Timoleon-Achilleas
authors: TA
authors: Vyzantiadis
authors: Loukia
authors: L
authors: Zerva
authors: Aristea
authors: A
authors: Velegraki
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects*; D025141:Drug Resistance, Fungal; D006115:Greece; D006801:Humans; D016867:Immunocompromised Host; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents