title: Quantum-cascade laser-based vibrational circular dichroism.
abstract: Vibrational circular dichroism (VCD) spectra were recorded with a tunable external-cavity quantum-cascade laser (QCL). In comparison with standard thermal light sources in the IR, QCLs provide orders of magnitude more power and are therefore promising for VCD studies in strongly absorbing solvents. The brightness of this novel light source is demonstrated with VCD and IR absorption measurements of a number of compounds, including proline in water.
authors: Institute for Pharmaceutical Sciences, University of Freiburg, Albertstr. 25, 79104 Freiburg, Germany.
authors: Steffen
authors: S
authors: Lüdeke
authors: Marcel
authors: M
authors: Pfeifer
authors: Peer
authors: P
authors: Fischer
mesh_terms: D002942:Circular Dichroism / Q000191:economics / Q000295:instrumentation*; D004867:Equipment Design; D054023:Lasers, Semiconductor; D011392:Proline / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D011392:Proline