title: Leukemia and lymphoma in pregnancy.
abstract: Treatment of pregnant women with chemotherapy may pose a risk to the fetus, raising therapeutic, ethical, moral, and social dilemmas. Publications on this issue are limited to retrospective series and case reports, thus further complicating decision making. Diagnosis and staging are usually performed as in nonpregnant women, but procedures that expose the fetus to radiation are excluded. Chemotherapy is not recommended in the first trimester to avoid fetal malformations. Thus, the option is either treatment delay or pregnancy termination. Later in pregnancy, treatment is often initiated without delay, with no apparent evidence of teratogenicity.
authors: Department of Medicine, Hematology Institute, Meir Medical Center, Kfar Saba, Israel.
authors: Uri
authors: U
authors: Abadi
authors: Gideon
authors: G
authors: Koren
authors: Michael
authors: M
authors: Lishner
mesh_terms: D000367:Age Factors; D005260:Female; D006801:Humans; D015994:Incidence; D007938:Leukemia / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D008223:Lymphoma / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*