title: Rhenium(IV) compounds inducing apoptosis in cancer cells.
abstract: The anticancer properties of a series of mononuclear Re(IV) compounds of formula ReCl(4)L (where L is bpy = 2,2'-bipyridine; bpym = 2,2'-bipyrimidine; dmbpy = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) were investigated for the first time. All compounds displayed potent in vitro antiproliferative activity against selected cancer cells.
authors: Centro di Eccellenza CEMIF.CAL, Dipartimento di Chimica, Università della Calabria, via P. Bucci 14/c, 87030 Arcavacata di Rende, Cosenza, Italy.
authors: José
authors: J
authors: Martínez-Lillo
authors: Teresa F
authors: TF
authors: Mastropietro
authors: Rosamaria
authors: R
authors: Lappano
authors: Antonio
authors: A
authors: Madeo
authors: Marta E
authors: ME
authors: Alberto
authors: Nino
authors: N
authors: Russo
authors: Marcello
authors: M
authors: Maggiolini
authors: Giovanni
authors: G
authors: De Munno
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry* / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D045744:Cell Line, Tumor / Q000187:drug effects*; D006801:Humans; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry* / Q000494:pharmacology*; D010618:Phenanthrolines / Q000737:chemistry* / Q000494:pharmacology*; D011725:Pyridines / Q000737:chemistry* / Q000494:pharmacology*; D012211:Rhenium / Q000737:chemistry*
chemical_list: C560551:4,4'-dimethyl-2,2'-bipyridine; D000970:Antineoplastic Agents; D008024:Ligands; D009942:Organometallic Compounds; D010618:Phenanthrolines; D011725:Pyridines; D015082:2,2'-Dipyridyl; D012211:Rhenium; C025205:1,10-phenanthroline