title: Lewis base catalyzed [4+2] annulation of electron-deficient chromone-derived heterodienes and acetylenes.
abstract: Lewis base catalyzed [4+2] annulation reactions between electron-deficient chromone oxa- and azadienes and acetylene carboxylates provide tricyclic benzopyrones inspired by natural products. An asymmetric synthesis of the tricyclic benzopyrones was developed by using modified cinchona alkaloids as enantiodifferentiating Lewis base catalysts.
authors: Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.
authors: Heiko
authors: H
authors: Dückert
authors: Vivek
authors: V
authors: Khedkar
authors: Herbert
authors: H
authors: Waldmann
authors: Kamal
authors: K
authors: Kumar
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D002930:Cinchona Alkaloids / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D004583:Electrons; D058115:Lewis Bases / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D002867:Chromones; D002930:Cinchona Alkaloids; D058115:Lewis Bases