title: Modification of Kirchhoff migration with variable sound speed and attenuation for acoustic imaging of media and application to tomographic imaging of the breast.
abstract: OBJECTIVE
  To explore the feasibility of improving cross-sectional reflection imaging of the breast using refractive and attenuation corrections derived from ultrasound tomography data.
  
  
  METHODS
  The authors have adapted the planar Kirchhoff migration method, commonly used in geophysics to reconstruct reflection images, for use in ultrasound tomography imaging of the breast. Furthermore, the authors extended this method to allow for refractive and attenuative corrections. Using clinical data obtained with a breast imaging prototype, the authors applied this method to generate cross-sectional reflection images of the breast that were corrected using known distributions of sound speed and attenuation obtained from the same data.
  
  
  RESULTS
  A comparison of images reconstructed with and without the corrections showed varying degrees of improvement. The sound speed correction resulted in sharpening of detail, while the attenuation correction reduced the central darkening caused by path length dependent losses. The improvements appeared to be greatest when dense tissue was involved and the least for fatty tissue. These results are consistent with the expectation that denser tissues lead to both greater refractive effects and greater attenuation.
  
  
  CONCLUSIONS
  Although conventional ultrasound techniques use time-gain control to correct for attenuation gradients, these corrections lead to artifacts because the true attenuation distribution is not known. The use of constant sound speed leads to additional artifacts that arise from not knowing the sound speed distribution. The authors show that in the context of ultrasound tomography, it is possible to construct reflection images of the breast that correct for inhomogeneous distributions of both sound speed and attenuation.
authors: Department of Physics and Astronomy, Wayne State University, Detroit, Michigan 48201, USA. schmidts@karmanos.org
authors: Steven
authors: S
authors: Schmidt
authors: Nebojsa
authors: N
authors: Duric
authors: Cuiping
authors: C
authors: Li
authors: Olivier
authors: O
authors: Roy
authors: Zhi-Feng
authors: ZF
authors: Huang
mesh_terms: D000162:Acoustics; D001940:Breast; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008327:Mammography; D013016:Sound; D014054:Tomography / Q000379:methods*; D016217:Ultrasonography, Mammary