title: Subthreshold depression in Parkinson's disease.
abstract: BACKGROUND
  Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood.
  
  
  METHODS
  Our study used standard DSM-IV and Judd criteria as well as motor, depression, and quality-of-life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups.
  
  
  RESULTS
  Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminished interest/pleasure) were more frequent in the depressed group compared with the subthreshold depressed, although the motor functions of these 2 groups did not differ significantly.
  
  
  CONCLUSIONS
  The Beck Depression Inventory score ranging from 9 to 15 points differentiates subthreshold depressed from nondepressed and depressed patients best.
authors: Department of Psychiatry, Zentrum für Integrative Psychiatrie, Kiel, Germany.
authors: Julia
authors: J
authors: Reiff
authors: Nele
authors: N
authors: Schmidt
authors: Bastian
authors: B
authors: Riebe
authors: Robert
authors: R
authors: Breternitz
authors: Josef
authors: J
authors: Aldenhoff
authors: Günther
authors: G
authors: Deuschl
authors: Karsten
authors: K
authors: Witt
mesh_terms: D000368:Aged; D003863:Depression / Q000175:diagnosis / Q000209:etiology*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications*; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric