title: In vitro reduction of dental erosion by low-concentration TiF4 solutions.
abstract: The aims of this study were to compare daily versus single applications of low-concentration TiF(4) solutions for reduction of enamel erosion and to evaluate the enamel surface loss due to application of these solutions. Sixty bovine enamel samples were randomly divided into 2 groups: single versus daily treatment with TiF(4) solution (ST vs. DT), which were subdivided into 5 subgroups (n = 6): 0% (control); 0.1, 0.5, 0.75 and 1% TiF(4) concentration. Fluoride treatment was performed by immersing specimens in 10 ml of the TiF(4) solutions for 5 min and rinsing them with tap water for 30 s. ST specimens were treated once only, DT specimens were treated before each erosion cycle. All specimens were subjected to 4 erosion cycles: 6 immersions of 2 min in Sprite, tap water rinse for 1 min and storage in artificial saliva for 1.5 h. Erosive enamel loss was measured using light profilometry, after each fluoride treatment and each erosive cycle. The values of surface loss/gain at application of the TiF(4) solutions did not significantly differ from zero. At the end of the 4 erosion cycles, 0.5% showed the least (ST: 3.45 ± 0.27 μm, DT: 1.08 ± 1.69 μm) and 1% showed the most surface loss (ST: 4.87 ± 1.13 μm, DT: 6.56 ± 1.49 μm). A significant reduction of surface loss was found only for 0.5% DT (p = 0.009). Within the limitations of an in vitro study, it was concluded that multiple applications of a 0.5% TiF(4) solution significantly reduced enamel erosion in vitro and caused no enamel loss at application.
authors: Department of Conservative Dentistry and Periodontology, Centre for Dentistry and Oral Hygiene, University Medical Centre Groningen, University of Groningen, The Netherlands.
authors: A M
authors: AM
authors: Vieira
authors: J L
authors: JL
authors: Ruben
authors: E M
authors: EM
authors: Bronkhorst
authors: M C D N J M
authors: MC
authors: Huysmans
mesh_terms: D000818:Animals; D002253:Carbonated Beverages / Q000009:adverse effects; D002417:Cattle; D003743:Dental Enamel / Q000473:pathology; D004305:Dose-Response Relationship, Drug; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use*; D011897:Random Allocation; D014025:Titanium / Q000008:administration & dosage / Q000627:therapeutic use*; D014077:Tooth Erosion / Q000188:drug therapy* / Q000209:etiology
chemical_list: D005460:Fluorides, Topical; D014025:Titanium; D005459:Fluorides; C032240:titanium tetrafluoride