title: [Pregnancy and essential thrombocytemia].
abstract: OBJECTIVE
  To evaluate the management and outcome of pregnancy in women with essential thrombocytemia.
  
  
  METHODS
  We conducted a retrospective study including all the pregnant women with essential thrombocytemia followed between January 2000 and January 2008 in a University Hospital (hôpital Jeanne-de-Flandre, Lille, France). We report our experience of 18 pregnancies in 13 women. The management and the complications of these pregnancies were reported.
  
  
  RESULTS
  All the patients were treated with low dose aspirin during the pregnancy. We observed one intrauterine death, one premature delivery at 29 weeks of gestation and six maternal haemorrhages at delivery (33%).
  
  
  CONCLUSIONS
  It is essential to treat these patients with low dose aspirin as soon as the pregnancy begins. Aspirin will be continued in postpartum with anticoagulant treatment. This management appears to improve the obstetric outcome and decrease the thrombotic complications usually described. A national register seems to be necessary to evaluate the complications occurring during pregnancy and the optimum follow-up.
authors: Pôle d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, Lille cedex, France.
authors: G
authors: G
authors: Giraudet
authors: B
authors: B
authors: Wibaut
authors: A-S
authors: AS
authors: Ducloy
authors: P
authors: P
authors: Deruelle
authors: S
authors: S
authors: Depret
authors: N
authors: N
authors: Cambier
authors: P
authors: P
authors: Vaast
authors: V
authors: V
authors: Houfflin-Debarge
mesh_terms: D000328:Adult; D001241:Aspirin / Q000627:therapeutic use*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013920:Thrombocythemia, Essential / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin