title: [Study on the seasonal variations of the active components in Acer truncatum leaves and the inhibitory ability on fatty acid synthase].
abstract: OBJECTIVE
  To study the dynamic variations of the contents of total polyphenols, flvonoids and chlorogenic acid from Acer truncatum leaves in different months, and their inhibitory activities on fatty acid synthase.
  
  
  METHODS
  Spectrophotometry was used to determine the contents of total polyphenols, flavonoids and chlorogenic acid in extracts and the extracts' inhibitory effects were also investigated.
  
  
  RESULTS
  All Leaves picked from May to November have inhibitory effect. But the contents of polyphenols in leaves of July appeared to be higher than other months', and consequently exhibited stronger inhibition against FAS.
  
  
  CONCLUSIONS
  A positive correlation between the content of polyphenols in leaves extract and the inhibitory efficacy on FAS could be established.
authors: College of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing 100069.
authors: Yuan-Jie
authors: YJ
authors: Fan
authors: Yan-Bin
authors: YB
authors: Ye
authors: Wen
authors: W
authors: Gao
authors: Feng
authors: F
authors: Zhang
authors: Ying-Xia
authors: YX
authors: Zhang
mesh_terms: D031002:Acer / Q000737:chemistry* / Q000254:growth & development; D002726:Chlorogenic Acid / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D064429:Fatty Acid Synthases / Q000037:antagonists & inhibitors*; D005419:Flavonoids / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D010636:Phenols / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry / Q000254:growth & development; D059808:Polyphenols; D012621:Seasons; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004791:Enzyme Inhibitors; D005419:Flavonoids; D010636:Phenols; D059808:Polyphenols; D002726:Chlorogenic Acid; D064429:Fatty Acid Synthases