title: Detection of the KPC gene in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii during a PCR-based nosocomial surveillance study in Puerto Rico.
abstract: A 6-month, PCR-based, island-wide hospital surveillance study of beta-lactam resistance in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii was conducted in Puerto Rico. Of 10,507 isolates, 1,239 (12%) unique, multi-beta-lactam-resistant isolates from all geographical regions were identified. The KPC gene was detected in 61 E. coli, 333 K. pneumoniae, 99 P. aeruginosa, and 41 A. baumannii isolates, indicating the widespread dissemination of the KPC gene in clinically significant nosocomial isolates.
authors: Department of Microbiology and Medical Zoology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico.
authors: Iraida E
authors: IE
authors: Robledo
authors: Edna E
authors: EE
authors: Aquino
authors: Guillermo J
authors: GJ
authors: Vázquez
mesh_terms: D040981:Acinetobacter baumannii / Q000201:enzymology; D001419:Bacteria / Q000201:enzymology* / Q000235:genetics; D003428:Cross Infection / Q000188:drug therapy*; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000201:enzymology; D005260:Female; D006801:Humans; D007711:Klebsiella pneumoniae / Q000201:enzymology; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*; D011550:Pseudomonas aeruginosa / Q000201:enzymology; D011647:Puerto Rico; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: C434283:beta-lactamase KPC-1; D001618:beta-Lactamases