title: Treatment of congenital heart disease: risk-reducing measures in young adults.
abstract: Adults with congenital heart disease form a new and relatively young population, since surgical treatment of heart defects became available three to four decades ago. Owing to improved survival this population is steadily growing in number and age. Little is known regarding long-term survival; however, late complications occur frequently. During adulthood, almost half of the patients have one or more complication, such as endocarditis, stroke, systemic or pulmonary hypertension, aortic aneurysm or dissection and arrhythmias. Heart failure and sudden cardiac death are the main causes of death. Treatment of adults with congenital heart disease is aimed at the reduction of symptoms, but also at minimizing the risk and severity of late complications. In this article the most recent advances in the treatment of congenital heart disease will be discussed. The main focus of the article will be on pharmacological, interventional and surgical interventions that reduce the risk of heart failure, arrhythmias, vascular complications, pulmonary hypertension and endocarditis.
authors: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
authors: Teun
authors: T
authors: van der Bom
authors: Paul
authors: P
authors: Luijendijk
authors: Berto J
authors: BJ
authors: Bouma
authors: Dave R
authors: DR
authors: Koolbergen
authors: Joris R
authors: JR
authors: de Groot
authors: Barbara J M
authors: BJ
authors: Mulder
authors: Barbara B J
authors: BB
authors: Mulder
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods*; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D014943:Global Health; D006330:Heart Defects, Congenital / Q000150:complications / Q000453:epidemiology / Q000601:surgery; D006333:Heart Failure / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D009017:Morbidity / Q000639:trends; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult