title: [Infective complications in patients with lung cancer].
abstract: BACKGROUND
  This study was aimed at analyzing the site, kind and type of infection which develop in patients having lung cancer at hospital treatment.
  
  
  METHODS
  Clinical data of the patients hospitalized for lung cancer were analyzed at the Clinic for Lung Diseases and Tuberculosis in Knez Selo in the period from January 2002 till December 2007. A great number of patients (1296-75.9%) had non-small cell lung cancer. In 1708 patients with lung cancer, 773 febrile episodes were recorded, i.e. 687 states of infections.
  
  
  RESULTS
  Most of the infections were recorded in the tracheobronchial tree (60.9%). The infection was confirmed microbiologically in 38% of infectious states. Predominant Gram positive pathogens were Staphylococcus aureus and Streptococcus, but among Gram negative pathogens there were Escherichia coli and Haemophilus influenzae.
  
  
  CONCLUSIONS
  A significantly better therapy response to antibiotics was found in the group of patients where microbiological agents were isolated (p < 0.05). The predominant site of infection in the patients with lung cancer is the tracheobronchial tree without a significant difference between frequency of Gram positive and Gram negative pathogens.
authors: Klinika za plućne bolesti i tuberkulozu Knez Selo, Klinicki centar Nis, Nis. milanrancic@gmail.com
authors: Milan
authors: M
authors: Rancić
authors: Lidija
authors: L
authors: Ristić
authors: Ivana
authors: I
authors: Stanković
mesh_terms: D001424:Bacterial Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D009894:Opportunistic Infections / Q000150:complications*; D012307:Risk Factors