title: [Acute results of percutaneous mitral balloon valvuloplasty].
abstract: OBJECTIVE
  We aimed to analyze acute clinical, echocardiographic, and hemodynamic results and long-term event-free survival of percutaneous mitral balloon valvuloplasty (PMBV) in the treatment of hemodynamically significant mitral stenosis (MS).
  
  
  METHODS
  We retrospectively reviewed 577 patients (454 females, 123 males; mean age 38±11 years) who underwent PMBV for moderate or severe MS. Acute procedural success was defined as the achievement of mitral valve area (MVA) >1.5 cm2 and absence of grade 3-4 mitral regurgitation. In addition, 489 patients were interrogated by phone calls for event-free survival (death, redo PMBV, mitral valve replacement) after at least one year (mean 54 months) of the procedure.
  
  
  RESULTS
  The procedure was successful in 547 patients (94.8%) and unsuccessful in 30 patients (5.2%). Among baseline echocardiographic and hemodynamic parameters, MVA was significantly lower (p=0.0001) and moderate/severe tricuspid regurgitation was significantly more common (p=0.031) in patients with failure. The mean Wilkins scores were similar in the two groups (p>0.05). Failure was related to suboptimal valve opening (MVA <1.5 cm2) in 20 patients (66.7%), and grade 3-4 mitral regurgitation in 10 patients (33.3%). There were no in-hospital death, cardiac tamponade, or cerebrovascular accident. Acute complications included iatrogenic atrial septal defect (n=51, 8.8%) and groin hematoma (n=4, 0.7%). Inquiry for long-term outcomes showed that four patients had died, while 21 patients and six patients had undergone mitral valve replacement and redo PMBV, respectively.
  
  
  CONCLUSIONS
  Our data suggest that PMBV is a safe and effective treatment option in MS and preprocedural MVA and tricuspid regurgitation are associated with acute failure of the procedure.
authors: Department of Cardiology, Türkiye Yüksek İhtisas Heart-Education and Research Hospital, Ankara, Turkey.
authors: Sule
authors: S
authors: Korkmaz
authors: Tolga
authors: T
authors: Aksu
authors: Hatice
authors: H
authors: Saşmaz
authors: Ayşe
authors: A
authors: Colak
authors: Mehmet Birhan
authors: MB
authors: Yılmaz
authors: Yesim
authors: Y
authors: Güray
authors: Umit
authors: U
authors: Güray
authors: Burcu
authors: B
authors: Demirkan
mesh_terms: D000328:Adult; D002404:Catheterization / Q000009:adverse effects / Q000379:methods*; D004452:Echocardiography; D005260:Female; D006119:Groin; D006344:Heart Septal Defects, Atrial / Q000453:epidemiology / Q000209:etiology; D006406:Hematoma / Q000453:epidemiology / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome