title: Synthesis and evaluation of a tri-tyrosine decorated dextran MR contrast agent for vulnerable plaque detection.
abstract: This communication reports the synthesis, characterization and in vivo evaluation in mice of a new tri-tyrosine conjugated MR contrast agent, which may help to identify vulnerable plaques in atherosclerosis by targeting the lipid core.
authors: Inserm, U698, Cardiovascular Bio-engineering, CHU X. Bichat, University Paris 7, Paris, F-75877, France.
authors: Anne
authors: A
authors: Beilvert
authors: Roger
authors: R
authors: Vassy
authors: Emmanuelle
authors: E
authors: Canet-Soulas
authors: Olivier
authors: O
authors: Rousseaux
authors: Luc
authors: L
authors: Picton
authors: Didier
authors: D
authors: Letourneur
authors: Frédéric
authors: F
authors: Chaubet
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis* / Q000737:chemistry; D003911:Dextrans / Q000138:chemical synthesis* / Q000737:chemistry; D008279:Magnetic Resonance Imaging / Q000379:methods*; D051379:Mice; D058226:Plaque, Atherosclerotic / Q000175:diagnosis*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D003287:Contrast Media; D003911:Dextrans; C101095:trityrosine; D014443:Tyrosine