title: The design of macromolecular crystallography diffraction experiments.
abstract: The measurement of X-ray diffraction data from macromolecular crystals for the purpose of structure determination is the convergence of two processes: the preparation of diffraction-quality crystal samples on the one hand and the construction and optimization of an X-ray beamline and end station on the other. Like sample preparation, a macromolecular crystallography beamline is geared to obtaining the best possible diffraction measurements from crystals provided by the synchrotron user. This paper describes the thoughts behind an experiment that fully exploits both the sample and the beamline and how these map into everyday decisions that users can and should make when visiting a beamline with their most precious crystals.
authors: Diamond Light Source, Harwell Science and Innovation Campus, Didcot, England. gwyndaf.evans@diamond.ac.uk
authors: Gwyndaf
authors: G
authors: Evans
authors: Danny
authors: D
authors: Axford
authors: Robin L
authors: RL
authors: Owen
mesh_terms: D018360:Crystallography, X-Ray / Q000295:instrumentation* / Q000379:methods