title: The synthesis and bio-applications of magnetic and fluorescent bifunctional composite nanoparticles.
abstract: Magnetic-fluorescent composite nanoparticles as a new kind of nanoparticle have attracted much attention in recent years. The composite nanoparticles combine the fluorescent properties, magnetic properties and the physical properties of nano-size, so they can offer a range of potential applications, such as bioseparation and bio-imaging, tumor cell localization, and even cancer treatment. This Minireview will introduce the main synthesis strategies for the fabrication of magnetic-fluorescent composite nanoparticles, the current and potential bio-application of magnetic-fluorescent nanocomposites, including protein and DNA separation and detection, bio-imaging and sorting in vitro and in vivo, drug delivery and the cancer treatment.
authors: Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
authors: Guannan
authors: G
authors: Wang
authors: Xingguang
authors: X
authors: Su
mesh_terms: D000818:Animals; D004247:DNA / Q000032:analysis; D003952:Diagnostic Imaging; D016503:Drug Delivery Systems / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D053768:Metal Nanoparticles; D051379:Mice; D053761:Nanocomposites; D036103:Nanotechnology / Q000379:methods; D009369:Neoplasms / Q000628:therapy; D010316:Particle Size; D045663:Quantum Dots
chemical_list: D005456:Fluorescent Dyes; D004247:DNA