title: Fat injections for the management of post-parotidectomy Frey syndrome: a technical note.
abstract: OBJECTIVE
  Frey syndrome (profuse sweating and cutaneous flushing in the area innervated by the auriculotemporal nerve) is a frequent and unpleasant complication of parotidectomy. Fat injections may be useful in preventing the abnormal nerve neo-anastomoses sprouting to the sweat glands that are responsible for gustatory sweating, but have never been used before.
  
  
  METHODS
  We describe the use of fat injections into the parotid gland of four patients with post-parotidectomy Frey syndrome.
  
  
  RESULTS
  All of the patients experienced a clinical and subjective improvement, although slight sweating persisted. There were no untoward effects during the procedure and, in particular, no facial nerve impairment.
  
  
  CONCLUSIONS
  On the basis of our experience minimally invasive fat injections can be considered in the case of post-parotidectomy Frey syndrome, but patients should be informed that subsequent procedures may be needed to achieve a definitive result.
authors: Department of Specialist Surgical Sciences, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Via F. Sforza 35, 20122 Milan, Italy. sara.torretta@policlinico.mi.it
authors: Sara
authors: S
authors: Torretta
authors: Lorenzo
authors: L
authors: Pignataro
authors: Pasquale
authors: P
authors: Capaccio
authors: Alessandra
authors: A
authors: Brevi
authors: Riccardo
authors: R
authors: Mazzola
mesh_terms: D017667:Adipocytes / Q000637:transplantation*; D000368:Aged; D005223:Fats / Q000008:administration & dosage*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D019647:Oral Surgical Procedures / Q000009:adverse effects*; D010306:Parotid Gland / Q000601:surgery*; D013545:Sweat Glands / Q000294:innervation; D013547:Sweating, Gustatory / Q000209:etiology / Q000517:prevention & control*
chemical_list: D005223:Fats