title: Burden of disease and costs of treating rotavirus diarrhea in Mexican children for the period 2001-2006.
abstract: OBJECTIVE
  To estimate the health impact and the costs of treatment associated with rotavirus diarrhea in six yearly cohorts (2001-2006) of Mexican infants.
  
  
  METHODS
  The perspective of study is from the health care system. We estimated the effect of rotavirus diarrhea on disability adjusted life years (DALYS) and diarrhea treatment costs in hypothetical cohorts of infants who are followed from birth up to five years of age beginning in years from 2001 to 2006. We used information from administrative databases on mortality and health care from the National System of Information on Health and from the Mexican Institute for Social Security to feed a decision analysis to project the burden of disease and costs of treatment.
  
  
  RESULTS
  Estimates of DALYS were 19,426 in 2001 and decreased by 28.9% for 2006 meanwhile costs of treatment were relatively constant, estimated at US$ 38.7 million and increased only by 5%.
  
  
  CONCLUSIONS
  Rotavirus diarrhea in Mexican children is a major disease burden, presenting significant treatment costs. Rotavirus diarrhea mortality is decreasing; however this has not led to a steady decrease in treatment costs in the 6 years period of analysis. A sensitivity analysis showed that incidences of rotavirus diarrhea as well as the parameters associated with health-care access were the main factors, which had a significant effect on the projected burden of disease and costs.
authors: Unidad de Investigación en Economía de la Salud, Instituto Mexicano del Seguro Social, 3er piso, Edificio de Monjas, Centro Médico Nacional Siglo XXI, Av, Cuauhtemoc 330, Colonia Doctores, Delegación Cuauhtémoc, 06720 México, DF, Mexico. victor.granados@imss.gob.mx
authors: Víctor
authors: V
authors: Granados-García
authors: F Raúl
authors: FR
authors: Velázquez
authors: Jorge
authors: J
authors: Salmerón
authors: Nuria
authors: N
authors: Homedes
authors: Guillermo
authors: G
authors: Salinas-Escudero
authors: Gabriela
authors: G
authors: Morales-Cisneros
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000191:economics* / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008800:Mexico / Q000453:epidemiology; D012400:Rotavirus Infections / Q000191:economics* / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy