title: Catalytic asymmetric addition of arylboronic acids to isatins using C2-symmetric cationic N-heterocyclic carbenes (NHCs) Pd2+ diaqua complexes as catalysts.
abstract: A catalytic asymmetric addition of arylboronic acids to isatins has been achieved by using chiral cationic C(2)-symmetric N-heterocyclic carbene (NHC) Pd(2+) diaqua complexes as the catalysts. The reaction can be performed under convenient conditions to give the corresponding adducts in good to high yields (79-94%) and moderate to excellent enantioselectivities (up to 94% ee) in the presence of LiOAr as the promoter which was generated in situ.
authors: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors: Zhen
authors: Z
authors: Liu
authors: Peng
authors: P
authors: Gu
authors: Min
authors: M
authors: Shi
authors: Patrick
authors: P
authors: McDowell
authors: Guigen
authors: G
authors: Li