title: Nanocrystal technology in the delivery of poorly soluble drugs: an overview.
abstract: Extensive attempts to overcome problems related to solubility of drugs for maximizing bioavailability at targeted sites in the body have been made. The issue of drug solubility appears to attract the continued interest of pharmaceutical manufacturers. In this context, nanocrystallization has emerged as an important tool. In the present review, the authors discuss the advantages of nanocrystallized drugs and examine the products available in the market as well as drugs in the pipeline using nanocrystal-based formulations, which are being developed by pharmaceutical companies for drug delivery.
authors: Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221005, India.
authors: Ramesh C
authors: RC
authors: Nagarwal
authors: Rakesh
authors: R
authors: Kumar
authors: Meenakshi
authors: M
authors: Dhanawat
authors: Nirupam
authors: N
authors: Das
authors: J K
authors: JK
authors: Pandit
mesh_terms: D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*; D012995:Solubility; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004364:Pharmaceutical Preparations