title: [Antitumor activities of liposoluble components of caulis Marsdeniae tenocissimae and analysis on its chemical constituents].
abstract: OBJECTIVE
  To study the antitumor activities of the liposoluble components from caulis Marsdenia tenocissimae and analyze its chemical constituents.
  
  
  METHODS
  The supercritical fluid extraction was used to extract the liposoluble components from caulis M. tenocissimae. MIT test was applied to study the anticancer effects of liposoluble components on growth inhibition in human liver cancer line HepG-2 cells, and the chemical constituents were analyzed by gas chromatography/mass spectrometry (GC-MS).
  
  
  RESULTS
  The liposoluble components of caulis M. tenocissimae have obvious growth inhibitory action to HepG-2 cells. Twenty-four compounds were identified and their relative contents were determined.
  
  
  CONCLUSIONS
  The liposoluble components from caulis M. tenocissimae have antitumor activities, and its pharmacological activity is related to its chemical constituents.
authors: Department of Drug, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.
authors: Hui
authors: H
authors: Zhang
authors: Zhidong
authors: Z
authors: Pei
authors: Xiuya
authors: X
authors: Zhang
authors: Tingguo
authors: T
authors: Kang
mesh_terms: D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D056945:Hep G2 Cells; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D031101:Marsdenia / Q000737:chemistry*; D012995:Solubility
chemical_list: D000970:Antineoplastic Agents; D008055:Lipids