title: Presbyequilibrium in the oldest old, a combination of vestibular, oculomotor and postural deficits.
abstract: OBJECTIVE
  Dizziness, impaired balance and fear of falling are common complaints in the elderly. We evaluated the association of vestibular symptoms with vestibular findings in the elderly by posturography and video-oculography (VOG).
  
  
  METHODS
  We studied 38 oldest old subjects (≥ 85 yrs, mean age 89) living in a residential home. Vestibular symptoms were taken with a structured questionnaire, the Mini Mental State Examination (MMSE) was scored and any falls were recorded over a period of 12 months. Posturography was measured with a force platform and eye movements were measured by video-oculography.
  
  
  RESULTS
  In the majority of the elderly, vestibular abnormalities were found, such as reduced vestibulo-ocular reflex gain 6/38, spontaneous nystagmus 5/38, gaze deviation nystagmus 5/38, head shaking nystagmus 9/38, pathologic head thrust test 10/38, and positional nystagmus 17/38. Posturography demonstrated two major findings: the body support area was limited and the use of vision for postural control was reduced. In principal component analysis of the vertigo, four major factors described elements of failure in the vestibular and other systems important to maintenance of balance: episodic vertigo, postural instability, multisystem failure (frail) and presyncopal imbalance. These four factors were associated in different degrees to vestibular abnormalities and falls. During the follow-up period, in 19 elderly (19/38), one or more falls were recorded.
  
  
  CONCLUSIONS
  Progressive loss of balance in the aged, or "presbyequilibrium," is a complex and incompletely understood process involving vestibular, oculomotor, visual acuity, proprioception, motor, organ system and metabolic weaknesses and disorders. These factors provide a potential basis for streamlining diagnostic evaluations and aiding in planning for effective therapy. In oldest old, these problems are magnified, increasing the need for additional expertise in their care, which may be met by training specialized healthcare staff.
authors: Department of Otolaryngology, University Hospital of Tampere, Teiskontie 35, Tampere 33521, Finland.
authors: Eeva
authors: E
authors: Tuunainen
authors: Dennis
authors: D
authors: Poe
authors: Pirkko
authors: P
authors: Jäntti
authors: Kirsi
authors: K
authors: Varpa
authors: Jyrki
authors: J
authors: Rasku
authors: Esko
authors: E
authors: Toppila
authors: Ilmari
authors: I
authors: Pyykkö
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000367:Age Factors; D000369:Aged, 80 and over; D004244:Dizziness / Q000453:epidemiology* / Q000503:physiopathology; D005133:Eye Movements; D005260:Female; D005500:Follow-Up Studies; D016330:Frail Elderly; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000453:epidemiology* / Q000503:physiopathology; D004856:Postural Balance; D012027:Reflex, Vestibulo-Ocular; D011795:Surveys and Questionnaires; D014717:Vertigo / Q000453:epidemiology* / Q000503:physiopathology