title: Human pluripotent stem cells: decoding the naïve state.
abstract: Human pluripotent stem cells play a central role in regenerative medicine and tissue engineering. These versatile cells can exist in a range of manipulable states with distinct functionalities, from the late epiblast stage represented by the conventional human embryonic stem cells (hESCs) to the mouse ESC-like naïve state. These functional states must be fully characterized if we are to harness the power of pluripotent stem cells to transform clinical medicine and therapeutics discovery.
authors: Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
authors: Wenlin
authors: W
authors: Li
authors: Sheng
authors: S
authors: Ding
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D002454:Cell Differentiation / Q000502:physiology; D002478:Cells, Cultured; D006801:Humans; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology / Q000502:physiology*; D051381:Rats; D044968:Regenerative Medicine / Q000379:methods; D023822:Tissue Engineering / Q000379:methods