title: Initial observations using a novel "cine" magnetic resonance imaging technique to detect changes in abdominal motion caused by encapsulating peritoneal sclerosis.
abstract: Encapsulating peritoneal sclerosis (EPS) is an uncommon complication of peritoneal dialysis (PD), with high mortality and morbidity. The peritoneum thickens, dysfunctions, and forms a cocoon that progressively "strangulates" the small intestine, causing malnutrition, ischemia, and infarction. There is as yet no reliable noninvasive means of diagnosis, but recent developments in image analysis of cine magnetic resonance imaging for the recognition of adhesions offers a way forward. We used this protocol before surgery in 3 patients with suspected EPS. Image analysis revealed patterns of abdominal movement that were markedly different from the patterns in healthy volunteers. The volunteers showed marked movement throughout the abdomen; in contrast, movement in EPS patients was restricted to just below the diaphragm. This clear difference provides early "proof of principle" of the approach that we have developed.
authors: Department of Radiology, Rotherham General Hospital NHS Foundation Trust, Rotherham, UK.
authors: Benjamin
authors: B
authors: Wright
authors: Angela
authors: A
authors: Summers
authors: John
authors: J
authors: Fenner
authors: Richard
authors: R
authors: Gillott
authors: Charles E
authors: CE
authors: Hutchinson
authors: Paul A
authors: PA
authors: Spencer
authors: Martin
authors: M
authors: Wilkie
authors: Helen
authors: H
authors: Hurst
authors: Sarah
authors: S
authors: Herrick
authors: Paul
authors: P
authors: Brenchley
authors: Titus
authors: T
authors: Augustine
authors: Karna D
authors: KD
authors: Bardhan
mesh_terms: D000005:Abdomen / Q000503:physiopathology*; D000328:Adult; D001826:Body Fluids; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D056627:Peritoneal Fibrosis / Q000175:diagnosis* / Q000503:physiopathology*; D055815:Young Adult