title: Study of HLA Class I gene in Indian schizophrenic patients of Siliguri, West Bengal.
abstract: The authors studied the prevalence of the human leukocyte antigen (HLA) Class I gene in 136 (85 male, 51 female) India-born schizophrenia patients residing in and around the Siliguri subdivision of West Bengal by the PCR-SSP method. The control group consisted of 150 age- and sex-matched healthy individuals from the same ethnic group as the patients. Increased frequency of HLA A*03 as well as decreased frequencies of HLA A*31 and HLA B*51, was noted. The study suggests the possible existence of a susceptibility locus for schizophrenia within the HLA region.
authors: Department of Zoology, University of North Bengal, Siliguri, West Bengal, India.
authors: Bisu
authors: B
authors: Singh
authors: Nirmal Kumar
authors: NK
authors: Bera
authors: Santanu
authors: S
authors: De
authors: Chittaranjan
authors: C
authors: Nayak
authors: Tapas Kumar
authors: TK
authors: Chaudhuri
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D005805:Genes, MHC Class I / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000379:methods; D005838:Genotype; D006680:HLA Antigens; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D007194:India / Q000453:epidemiology / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D006680:HLA Antigens; D015395:Histocompatibility Antigens Class I