title: Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents.
abstract: Butamidine analogues possessing unsaturation in the ether bridge between the bisamidinophenyl or bisimidazolinophenyl functionalities have been synthesized as semirigid congeners of pentamidine. These compounds demonstrated good anti-P. carinii pueumonia activity in a rat model of the disease.
authors: College of Pharmacy, Xavier University of Louisiana, New Orleans, LA 70125.
authors: Isaac O
authors: IO
authors: Donkor
authors: Susan K
authors: SK
authors: Jones
authors: Richard R
authors: RR
authors: Tidwell