title: Two amino acid changes located in the alpha 1 domain specify the novel HLA-B*27:67 allele affecting the peptide-binding-site characteristics.
abstract: The novel HLA-B*27:67 contains three nucleotide substitutions in exon 2 leading to two amino acid changes.
authors: Institute for Transfusion Medicine and Immunohaematology, German Red Cross Blood Donor Service Baden-Wuerttemberg-Hessen, Frankfurt, Germany. p.becker@blutspende.de
authors: P S
authors: PS
authors: Becker
authors: R
authors: R
authors: Richter
authors: M
authors: M
authors: Schulz
authors: E
authors: E
authors: Seifried
authors: C
authors: C
authors: Seidl
mesh_terms: D000483:Alleles; D001483:Base Sequence; D001665:Binding Sites; D001787:Blood Group Incompatibility; D005091:Exons; D015235:HLA-B Antigens / Q000737:chemistry / Q000235:genetics*; D006239:Haplotypes; D006650:Histocompatibility Testing / Q000379:methods; D006801:Humans; D008957:Models, Genetic; D008969:Molecular Sequence Data; D009711:Nucleotides / Q000235:genetics; D010455:Peptides / Q000737:chemistry; D017434:Protein Structure, Tertiary; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D013234:Stem Cells / Q000166:cytology
chemical_list: D015235:HLA-B Antigens; D009711:Nucleotides; D010455:Peptides