title: Giant liposarcoma of the esophagus with Li-Fraumeni-like syndrome.
abstract: Primary esophageal liposarcoma is a rare malignancy, with only 25 cases reported in the English literature. In this report, we present a new case of giant esophageal liposarcoma in a 49-year-old woman with a family history of upper gastrointestinal tract cancer. This was a transmural tumor located in the lower esophagus. Subtotal esophagectomy was successfully performed, and histopathology revealed a well-differentiated liposarcoma. The patient was followed-up for 20 months without recurrence. However, asynchronous ovarian serous adenocarcinoma was found 1 year after the esophageal surgery, and Li-Fraumeni-like syndrome was diagnosed.
authors: Department of Thoracic Surgery, Center for Mini-invasive Thoracic Surgery, People's Hospital, Peking University, Beijing, China.
authors: Xizhao
authors: X
authors: Sui
authors: Yun
authors: Y
authors: Li
authors: Hui
authors: H
authors: Zhao
authors: Jun
authors: J
authors: Wang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000601:surgery; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016629:Esophagectomy; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000175:diagnosis*; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed