title: [Cutaneous cytotoxic T-cell lymphoma].
abstract: Cutaneous cytotoxic T-cell lymphoma is a rare variant of cutaneous T-cell lymphoma, which shows immunoreactivity for CD56+. We report on an 83-year old woman with numerous skin infiltrates and nodules mainly on her face and trunk. Histopathologic criteria lead to the diagnosis of cutaneous cytotoxic T-cell lymphoma. Bexarotene was not tolerated because of cardiac insufficiency, but treatment with methotrexate (7.5 mg once weekly) led to prompt regression of all lesions.
authors: Klinik für Dermatologie und Allergologie, RWTH Aachen University, Pauwelsstraße 30, Aachen, Germany. aweinstabl@ukaachen.de
authors: A
authors: A
authors: Weinstabl
authors: M
authors: M
authors: Megahed
authors: A
authors: A
authors: Rütten
authors: A
authors: A
authors: Rübben
mesh_terms: D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy* / Q000473:pathology*; D008727:Methotrexate / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate