title: Chiral Brønsted acid catalysis for enantioselective Hosomi-Sakurai reaction of imines with allyltrimethylsilane.
abstract: The chiral Brønsted acid (1b or 1c) has been shown to initiate the Hosomi-Sakurai reaction of imines with excellent enantioselectivities. The combined Brønsted acid system has been developed to offer a new class of chiral Brønsted acid catalysis. The present system proceeds through regeneration of the chiral Brønsted acid by proton transfer from additional Brønsted acid to silylated chiral Brønsted acid, a newly elucidated mechanism for the role of the additional Brønsted acid.
authors: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan. momiyama@m.tohoku.ac.jp
authors: Norie
authors: N
authors: Momiyama
authors: Hayato
authors: H
authors: Nishimoto
authors: Masahiro
authors: M
authors: Terada