title: Triazinyl porphyrin-based photoactive cotton fabrics: preparation, characterization, and antibacterial activity.
abstract: In the present work, we report on the synthesis of cellulose cotton fibers bearing different types of photosensitizers with the aim to prepare new efficient polymeric materials for antimicrobial applications. Anionic, neutral, and cationic amino porphyrins have been covalently grafted on cotton fabric, without previous chemical modification of the cellulosic support, using a 1,3,5-triazine derivative as the linker. The obtained porphyrin-grafted cotton fabrics were characterized by infrared (ATR-FTIR), diffuse reflectance UV-vis (DRUV) spectroscopies, and thermogravimetric analysis (TGA) to confirm the triazine linkage. Antimicrobial activity of porphyrin-cellulose materials was tested under visible light irradiation against Staphylococcus aureus and Escherichia coli . The results showed excellent activity on the Gram-positive bacterium, showing structure-activity relationship, although no photodamage of the Gram-negative microorganism was recorded. A mechanism of bacterial inactivation by photosensitive surfaces is proposed.
authors: Laboratoire de Chimie des Substances Naturelles, Université de Limoges, EA 1069, Limoges, France.
authors: Cyril
authors: C
authors: Ringot
authors: Vincent
authors: V
authors: Sol
authors: Matthieu
authors: M
authors: Barrière
authors: Naïma
authors: N
authors: Saad
authors: Philippe
authors: P
authors: Bressollier
authors: Robert
authors: R
authors: Granet
authors: Pierre
authors: P
authors: Couleaud
authors: Céline
authors: C
authors: Frochot
authors: Pierre
authors: P
authors: Krausz
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D032561:Cotton Fiber; D008027:Light; D008855:Microscopy, Electron, Scanning; D011166:Porphyrins / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013818:Thermogravimetry; D014227:Triazines / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D011166:Porphyrins; D014227:Triazines