title: Synthesis of S-(2-thioxo-1,3-dithiolan-4-yl)methyl dialkylcarbamothioate and S-thiiran-2-ylmethyl dialkylcarbamothioate via intermolecular O-S rearrangement in water.
abstract: A facile synthesis of S-(2-thioxo-1,3-dithiolan-4-yl)methyl dialkylcarbamothioates (3) and S-thiiran-2-ylmethyl dialkylcarbamothioate (5) has been reported by the reaction of 5-(chloromethyl)-1,3-oxathiolane-2-thione (1) with sodium dialkylcarbamodithioate (2) and dialkylamine (4), respectively, through intermolecular O-S rearrangement in water. A plausible mechanism of formation of the title compounds has also been proposed.
authors: Medicinal & Process Chemistry Division, Central Drug Research Institute (CSIR), Lucknow-226001, India.
authors: Nand
authors: N
authors: Lal
authors: Lalit
authors: L
authors: Kumar
authors: Amit
authors: A
authors: Sarswat
authors: Santosh
authors: S
authors: Jangir
authors: Vishnu Lal
authors: VL
authors: Sharma
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013457:Sulfur Compounds / Q000138:chemical synthesis*; D014867:Water / Q000737:chemistry*
chemical_list: C559809:S-(2-thioxo-1,3-dithiolan-4-yl)methyl 4-methylpiperazine-1-carbothioate; D013457:Sulfur Compounds; D014867:Water