title: Multiple FtsZ2 isoforms involved in chloroplast division and biogenesis are developmentally associated with thylakoid membranes in Arabidopsis.
abstract: Seed plants and algae have two distinct FtsZ protein families, FtsZ1 and FtsZ2, involved in plastid division. Distinctively, seed plants and mosses contain two FtsZ2 family members (FtsZ2-1 and FtsZ2-2) thus raising the question of the role of these FtsZ2 paralogs in plants. We show that both FtsZ2 paralogs, in addition to being present in the stroma, are associated with the thylakoid membranes and that association is developmentally regulated. We also show that several FtsZ2-1 isoforms are present with distinct intra-plastidial localization. Mutant analyses show that FtsZ2-1 is essential for chloroplast division and that FtsZ2-2 plays a specific role in chloroplast morphology and internal organisation in addition to participating in chloroplast partition.
authors: Laboratoire de Physiologie Cellulaire Végétale, CNRS-(UMR5168)/INRA-(UMR1200)/UJF-Grenoble 1/CEA-iRTSV, Institut de Recherches en Technologies et Sciences pour le Vivant, CEA-Grenoble, 17 Rue des Martyrs, F-38054 Grenoble, France.
authors: Mohamed
authors: M
authors: Karamoko
authors: El-Sayed
authors: el-S
authors: El-Kafafi
authors: Paul
authors: P
authors: Mandaron
authors: Silva
authors: S
authors: Lerbs-Mache
authors: Denis
authors: D
authors: Falconet
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D002736:Chloroplasts / Q000378:metabolism* / Q000648:ultrastructure; D015151:Immunoblotting; D008854:Microscopy, Electron; D010802:Phylogeny; D020033:Protein Isoforms / Q000145:classification / Q000235:genetics / Q000378:metabolism; D020524:Thylakoids / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; C095113:FTSZ protein, Arabidopsis; D020033:Protein Isoforms