title: [Morphological analysis of bone dynamics and metabolic bone disease. Histomorphometric concepts of bone remodeling and modeling].
abstract: In tissue level turnover of bone cells, bone remodeling shows a sequential events of activation, resorption, reversal and formation. This may be observed as secondary osteons in the cortical bone and trabecular packets in the cancellous bone. Microcracks are repaired by targeted remodeling, and calcium is released by non-targeted remodeling. In macromodeling, a macroscopic size of a bone increases with growth, without changing its basic figure. In micromodelimg, a shift of trabecula, a minishift, is biomechnically controlled. New lamellar bone is added parallel to compressive and tensile force, and bone resorption occurs at the opposite surface of formation. In minimodeling new lamellar bone is formed with a sequence of activation, then directly formation, without scalloping at the cement line between newly formed bone and its basic bone.
authors: Department of Health Informatics, Niigata University of Health and Welfare.
authors: Hideaki E
authors: HE
authors: Takahashi
mesh_terms: D000818:Animals; D001851:Bone Diseases, Metabolic / Q000378:metabolism* / Q000473:pathology*; D016723:Bone Remodeling / Q000502:physiology*; D001842:Bone and Bones / Q000166:cytology / Q000378:metabolism* / Q000473:pathology*; D006801:Humans; D010011:Osteocytes / Q000473:pathology / Q000502:physiology; D010012:Osteogenesis