title: Laser and topical mitomycin C for management of nasal synechia after FESS: a preliminary report.
abstract: The objective of the study is to assess the role of diode laser coupled with topical mitomycin C (MMC) in the management of synechia after endoscopic sinus surgery. Twenty-five patients with recurrent sinusitis due to synechia between the middle turbinate and lateral nasal wall after endoscopic sinus surgery were included in this study. Diode laser was used to divide the synechia and MMC was applied topically in the area of the middle meatus for 5 min. Patients were followed for 6 months to assess symptoms improvement, recurrence of synechia and CT scan changes. Most of our patients reported improvement of their symptoms, recurrent synechia occurred in 15% of the patients with significant improvement of the CT scan findings. In conclusion, the diode laser with topical MMC is an outpatient procedure which is simple, safe and effective in managing postoperative nasal synechia.
authors: Department of Otorhinolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt. ahesham73@yahoo.com
authors: Ahmed
authors: A
authors: Hesham
authors: Ahmed
authors: A
authors: Fathi
authors: Mahmoud
authors: M
authors: Attia
authors: Sherif
authors: S
authors: Safwat
authors: Ahmed
authors: A
authors: Hesham
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy; D004724:Endoscopy / Q000009:adverse effects* / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D015508:Nasal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D013517:Otorhinolaryngologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D010256:Paranasal Sinuses / Q000503:physiopathology / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000628:therapy; D011446:Prospective Studies; D012008:Recurrence; D018570:Risk Assessment; D012852:Sinusitis / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D016685:Mitomycin