title: Metabolic syndrome in patients with depressive disorder--features of comorbidity.
abstract: BACKGROUND
  Depression is associated with increased physical morbidity and overall mortality. The results of a previous investigation on the relationship of the metabolic syndrome and its single components with coronary heart disease, cardiovascular disease (CVD), and all-cause mortality suggested that the metabolic syndrome is a marker of CVD risk, but not above and beyond the risk associated with its individual components. The aim of this article is to review literature regarding prevalence of metabolic syndrome in patients with depressive disorder, and association between metabolic syndrome and depression.
  
  
  METHODS
  Literature research included structured searches of Medline and other publications on the subject of metabolic syndrome, particularly prevalence of metabolic syndrome in patients with depressive disorder, and association between metabolic syndrome and depression.
  
  
  CONCLUSIONS
  Prevalence of the metabolic syndrome in patients with depression is high and varies among the analysed studies. Some investigations showed association between metabolic syndrome and depression. Further investigations are necessary in order to clarify the association between metabolic syndrome and depression.
authors: University Department, Vrapče Psychiatric Hospital, Bolnička cesta 32, 10090 Zagreb, Croatia. okozumplik@hotmail.com
authors: Oliver
authors: O
authors: Kozumplik
authors: Suzana
authors: S
authors: Uzun
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001008:Anxiety Disorders / Q000453:epidemiology / Q000523:psychology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000523:psychology; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003865:Major Depressive Disorder / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D006963:Hyperphagia / Q000453:epidemiology / Q000523:psychology; D007899:Leisure Activities; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000523:psychology; D008875:Middle Aged; D012307:Risk Factors