title: Studies on functional connections between the supraoptic nucleus and the stomach in rats.
abstract: The present study was to investigate whether there are functional connections between the hypothalamic supraoptic nucleus (SON) and the stomach, which is the case with the paraventricular nucleus. The rats were divided into four groups. Group I: the neuronal discharge was recorded extracellularly in the NTS, DMV or SON before and after cold physiological saline (4°C) was perfused into the stomach and effused from the duodenum. Group II: the rats were stimulated as for Group I and c-Fos expression in NTS, DMV and SON was examined. Group III: the control to Group II. Group IV: gastric motility was recorded continuously before and after microinjection of L: -Glu into the SON. In Group I, the discharge frequency increased in all the three nuclei, while in Group II, Fos expression in NTS, DMV and SON was, respectively, greater than that of Group III. In Group IV, microinjection of L: -Glu (5 nmol) into SON significantly inhibited gastric motility. These data suggest there are functional connections between SON and stomach.
authors: Key Laboratory of Animal Resistance of Shandong Province, College of Life Science, Shandong Normal University, Jinan, 250014, Shandong, People's Republic of China.
authors: Chang-Liang
authors: CL
authors: Lu
authors: Zhao-Ping
authors: ZP
authors: Li
authors: Jian-Ping
authors: JP
authors: Zhu
authors: Dong-Qin
authors: DQ
authors: Zhao
authors: Hong-Bin
authors: HB
authors: Ai
mesh_terms: D000818:Animals; D003080:Cold Temperature; D005753:Gastric Mucosa / Q000378:metabolism; D018698:Glutamic Acid / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism / Q000502:physiology; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism / Q000502:physiology; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis / Q000235:genetics; D051381:Rats; D017208:Rats, Wistar; D012007:Rectum / Q000294:innervation / Q000502:physiology; D012965:Sodium Chloride; D013270:Stomach / Q000294:innervation*; D013495:Supraoptic Nucleus / Q000378:metabolism / Q000502:physiology*; D014630:Vagus Nerve / Q000378:metabolism / Q000502:physiology
chemical_list: D016760:Proto-Oncogene Proteins c-fos; D018698:Glutamic Acid; D012965:Sodium Chloride