title: Stopping RNA interference at the seed.
abstract: MicroRNAs (miRNAs) regulate expression of more than one half of the genes in the human genome. A study now reports a new method for selectively silencing whole families of miRNAs, thus providing a new paradigm for disease therapy.
authors: Department of Molecular and Cellular Biology, Beckman Research Institute of the City of Hope, Duarte, California, USA. jrossi@coh.org
authors: John J
authors: JJ
authors: Rossi
mesh_terms: D005821:Genetic Techniques; D015894:Genome, Human; D006801:Humans; D035683:MicroRNAs / Q000037:antagonists & inhibitors / Q000235:genetics; D009841:Oligonucleotides / Q000737:chemistry / Q000235:genetics; D034622:RNA Interference
chemical_list: D035683:MicroRNAs; D009841:Oligonucleotides; C477371:locked nucleic acid