title: Bioactive glass granules: a suitable bone substitute material in the operative treatment of depressed lateral tibial plateau fractures: a prospective, randomized 1 year follow-up study.
abstract: Purpose of this study was to compare bioactive glass and autogenous bone as a bone substitute material in tibial plateau fractures. We designed a prospective, randomized study consisting of 25 consecutive operatively treated patients with depressed unilateral tibial comminuted plateau fracture (AO classification 41 B2 and B3).14 patients (7 females, 7 males, mean age 57 years, range 25-82) were randomized in the bioglass group (BG) and 11 patients (6 females, 5 males, mean age 50 years, range 31-82) served as autogenous bone control group (AB). Clinical examination of the patients was performed at 3 and 12 months, patients' subjective and functional results were evaluated at 12 months. Radiological analysis was performed preoperatively, immediately postoperatively and at 3 and 12 months. The postoperative redepression for both studied groups was 1 mm until 3 months and remained unchanged at 12 months. No differences were identified in the subjective evaluation, functional tests and clinical examination between the two groups during 1 year follow-up. We conclude that bioactive glass granules can be clinically used as filler material instead of autogenous bone in the lateral tibial plateau compression fractures.
authors: Sports Clinic Mehiläinen, Turku, Finland. jouni.heikkila@mehilainen.fi
authors: Jouni T
authors: JT
authors: Heikkilä
authors: Juha
authors: J
authors: Kukkonen
authors: Allan J
authors: AJ
authors: Aho
authors: Susanna
authors: S
authors: Moisander
authors: Timo
authors: T
authors: Kyyrönen
authors: Kimmo
authors: K
authors: Mattila
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018786:Bone Substitutes / Q000737:chemistry*; D019245:Compressive Strength; D005260:Female; D005500:Follow-Up Studies; D017102:Fracture Healing; D005898:Glass / Q000737:chemistry*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D013314:Stress, Mechanical; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D013978:Tibial Fractures / Q000473:pathology*
chemical_list: D018786:Bone Substitutes