title: Evaluation of dietetic advice for modification of cardiovascular disease risk factors in renal transplant recipients.
abstract: OBJECTIVE
  To investigate the effect of dietitian involvement in a multidisciplinary lifestyle intervention comparing risk factor modification for cardiovascular disease with standard posttransplant care in renal transplant recipients (RTR) with abnormal glucose tolerance (AGT).
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  Hospital outpatient department.
  
  
  METHODS
  Adult RTR with AGT.
  
  
  METHODS
  RTR with AGT were randomized to a lifestyle intervention that consisted of either regular consultations with the dietitian and multidisciplinary team or standard care.
  
  
  METHODS
  Dietary intake, physical activity (PA) levels, cardiorespiratory fitness (CF), and anthropometry.
  
  
  RESULTS
  Total fat and percent saturated fat intake rates were significantly lower in the intervention group as compared with the control group at 2-year follow-up, 54 g (16 to 105 g) versus 65 g (34 to 118 g), P = .01 and 10% (5% to 17%) versus 13% (4% to 20%), P = .05., respectively. There was a trend for an overweight (but not obese) individual to lose more weight in the intervention group (4% loss vs. a gain of 0.25% at the 2-year follow-up). Overall, RTR were significantly less fit than age- and gender-matched controls, mean peak oxygen uptake was 19.42 ± 7.09 mL/kg per minute versus 28.35 ± 8.80 mL/kg per minute, P = .000. Simple exercise advice was not associated with any improvement in total PA or CF in either group at the 2-year follow-up.
  
  
  CONCLUSIONS
  Dietary advice can contribute to healthier eating habits and a trend for weight loss in RTR with AGT. These improvements in conjunction with multidisciplinary care and pharmacological treatment can lead to improvements in cardiovascular risk factors such as lipid profile. Simple advice to increase PA was not effective in improving CF and other measures are needed.
authors: Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia. lkorazio@gmail.com
authors: Linda K
authors: LK
authors: Orazio
authors: Nicole M
authors: NM
authors: Isbel
authors: Kirsten A
authors: KA
authors: Armstrong
authors: Jodie
authors: J
authors: Tarnarskyj
authors: David W
authors: DW
authors: Johnson
authors: Rachael E
authors: RE
authors: Hale
authors: Mohamed
authors: M
authors: Kaisar
authors: Merrilyn D
authors: MD
authors: Banks
authors: Ingrid J
authors: IJ
authors: Hickman
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D001315:Australia; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control*; D038441:Diet, Mediterranean; D004041:Dietary Fats / Q000008:administration & dosage; D004046:Dietetics; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D058870:Food, Organic; D018149:Glucose Intolerance / Q000150:complications / Q000517:prevention & control; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009765:Obesity / Q000150:complications / Q000517:prevention & control; D010349:Patient Compliance; D012307:Risk Factors
chemical_list: D004041:Dietary Fats