title: Role of unit-specific combination antibiograms for improving the selection of appropriate empiric therapy for gram-negative pneumonia.
abstract: In an effort to improve the selection of appropriate empiric gram-negative therapy for pneumonia, we examined intensive care unit-specific combination antibiograms. These antibiograms were able to predict appropriate empiric gram-negative therapy. Empiric combination therapy based on unit-specific combination antibiograms may aid in the selection of therapy for gram-negative pneumonia.
authors: Department of Clinical, Social and Administrative Sciences, University of Michigan College of Pharmacy, Department of Pharmacy Services, University of Michigan Health System, Ann Arbor, Michigan 48235, USA. jpogue@dmc.org
authors: Jason M
authors: JM
authors: Pogue
authors: Cesar
authors: C
authors: Alaniz
authors: Peggy L
authors: PL
authors: Carver
authors: Melissa
authors: M
authors: Pleva
authors: Duane
authors: D
authors: Newton
authors: Daryl D
authors: DD
authors: DePestel
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination; D024841:Fluoroquinolones / Q000627:therapeutic use; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests / Q000379:methods*; D018410:Pneumonia, Bacterial / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification / Q000502:physiology; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D047090:beta-Lactams