title: Synthetic studies toward 13-oxyingenol: construction of the fully substituted tetracyclic compound.
abstract: 13-Oxyingenol and its derivatives have high levels of anti-HIV activity. A fully substituted tetracyclic skeleton of 13-oxyingenol is constructed by using spiro-cyclization and ring-closing olefin metathesis as key steps.
authors: Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tennodai, Tsukuba 305-8571, Japan.
authors: Takayuki
authors: T
authors: Ohyoshi
authors: Yamato
authors: Y
authors: Miyazawa
authors: Kenta
authors: K
authors: Aoki
authors: Satomi
authors: S
authors: Ohmura
authors: Yuki
authors: Y
authors: Asuma
authors: Ichiro
authors: I
authors: Hayakawa
authors: Hideo
authors: H
authors: Kigoshi
mesh_terms: D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D007536:Isomerism; D015394:Molecular Structure; D013141:Spiro Compounds / Q000737:chemistry
chemical_list: C559803:13-oxyingenol; D004224:Diterpenes; D006576:Heterocyclic Compounds, 4 or More Rings; D013141:Spiro Compounds