title: Bulk modulus of a protein active-site mimic.
abstract: Flexibility is an important property of porphyrins, both natural and synthetic. We applied two synchrotron-based techniques, nuclear resonance vibrational spectroscopy and inelastic X-ray scattering, to quantify this property by measuring the bulk modulus of a protein active-site mimic [chloro(octaethylporphyrinato)iron(III)] and the resilience of the iron environment. Their values are 6.95 ± 0.24 GPa and 15.4 ± 0.5 N/m, respectively.
authors: Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois, United States. leu@aps.anl.gov
authors: Bogdan M
authors: BM
authors: Leu
authors: J Timothy
authors: JT
authors: Sage
authors: Nathan J
authors: NJ
authors: Silvernail
authors: W Robert
authors: WR
authors: Scheidt
authors: Ahmet
authors: A
authors: Alatas
authors: Ercan E
authors: EE
authors: Alp
authors: Wolfgang
authors: W
authors: Sturhahn
mesh_terms: D000818:Animals; D032701:Biomimetics; D020134:Catalytic Domain; D006420:Hemeproteins / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D011166:Porphyrins / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D006420:Hemeproteins; D011166:Porphyrins