title: PdCl2-catalyzed efficient allylation and benzylation of heteroarenes under ligand, base/acid, and additive-free conditions.
abstract: We present a PdCl(2)-catalyzed protocol for highly efficient allylation and benzylation of a rich variety of N-, O-, and S-containing heteroarenes under base/acid, additive, and ligand-free conditions. The method represents the very few examples for simple, universally applicable, clean, and atom-efficient functionalization of heteroarenes.
authors: Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, Jilin, China.
authors: Feng-Quan
authors: FQ
authors: Yuan
authors: Lian-Xun
authors: LX
authors: Gao
authors: Fu-She
authors: FS
authors: Han
mesh_terms: D000143:Acids / Q000737:chemistry*; D001593:Benzyl Compounds / Q000737:chemistry*; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000143:Acids; D001593:Benzyl Compounds; D006571:Heterocyclic Compounds; D008024:Ligands; D010165:Palladium; C008756:palladium chloride