title: Effects of copper sulfate, tri-basic copper chloride, and zinc oxide on weanling pig performance.
abstract: Three experiments were conducted to evaluate the effects of increasing dietary Cu and Zn on weanling pig performance. Diets were fed in 2 phases: phase 1 from d 0 to 14 postweaning and phase 2 from d 14 to 28 in Exp. 1 and 2 and d 14 to 42 in Exp. 3. The trace mineral premix, included in all diets, provided 165 mg/kg of Zn from ZnSO(4) and 16.5 mg/kg of Cu from CuSO(4). In Exp. 1, treatments were arranged in a 2 × 3 factorial with main effects of added Cu from tri-basic copper chloride (TBCC; 0 or 150 mg/kg) and added Zn from ZnO (0, 1,500, or 3,000 mg/kg from d 0 to 14 and 0, 1,000, or 2,000 mg/kg from d 14 to 28). No Cu × Zn interactions were observed (P > 0.10). Adding TBCC or Zn increased (P < 0.05) ADG and ADFI during each phase. In Exp. 2, treatments were arranged in a 2 × 3 factorial with main effects of added Zn from ZnO (0 or 3,000 mg/kg from d 0 to 14 and 0 or 2,000 mg/kg from d 14 to 28) and Cu (control, 125 mg/kg of Cu from TBCC, or 125 mg/kg of Cu from CuSO(4)). No Cu × Zn interactions (P > 0.10) were observed for any performance data. Adding ZnO improved (P < 0.02) ADG and ADFI from d 0 to 14 and overall. From d 0 to 28, supplementing CuSO(4) increased (P < 0.02) ADG, ADFI, and G:F, and TBCC improved (P = 0.006) ADG. In Exp. 3, the 6 dietary treatments were arranged in a 2 × 2 factorial with main effects of added Cu from CuSO(4) (0 or 125 mg/kg) and added Zn from ZnO (0 or 3,000 mg/kg from d 0 to 14 and 0 or 2,000 mg/kg from d 14 to 42). The final 2 treatments were feeding added ZnO alone or in combination with CuSO(4) from d 0 to 14 and adding CuSO(4) from d 14 to 42. Adding ZnO increased (P < 0.04) ADG, ADFI, and G:F from d 0 to 14 and ADG from d 0 to 42. Dietary CuSO(4) increased (P < 0.004) ADG and ADFI from d 14 to 42 and d 0 to 42. From d 28 to 42, a trend for a Cu × Zn interaction was observed (P = 0.06) for ADG. This interaction was reflective of the numeric decrease in ADG for pigs when Cu and Zn were used in combination compared with each used alone. Also, numerical advantages were observed when supplementing Zn from d 0 to 14 and Cu from d 14 to 42 compared with all other Cu and Zn regimens. These 3 experiments show the advantages of including both Cu and Zn in the diet for 28 d postweaning; however, as evident in Exp. 3, when 3,000 mg/kg of Zn was added early and 125 mg/kg of Cu was added late, performance was similar or numerically greater than when both were used for 42 d.
authors: Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan 66506-0201, USA.
authors: N W
authors: NW
authors: Shelton
authors: M D
authors: MD
authors: Tokach
authors: J L
authors: JL
authors: Nelssen
authors: R D
authors: RD
authors: Goodband
authors: S S
authors: SS
authors: Dritz
authors: J M
authors: JM
authors: DeRouchey
authors: G M
authors: GM
authors: Hill
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002712:Chlorides / Q000008:administration & dosage / Q000494:pharmacology*; D003300:Copper / Q000008:administration & dosage / Q000494:pharmacology*; D019327:Copper Sulfate / Q000008:administration & dosage / Q000494:pharmacology*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D013552:Swine / Q000254:growth & development*; D014886:Weaning; D015034:Zinc Oxide / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D002712:Chlorides; C111994:atacamite; D003300:Copper; D019327:Copper Sulfate; D015034:Zinc Oxide