title: Use of human amniotic membrane as an interpositional material in treatment of temporomandibular joint ankylosis.
abstract: OBJECTIVE
  The aim of the study was to demonstrate whether the human amniotic membrane (HAM) as an interpositional material could prevent temporomandibular joint (TMJ) reankylosis in the randomized rabbit model.
  
  
  METHODS
  In our experimental study, 24 New Zealand white rabbits were used and all right joints were operated. The rabbits were divided into 2 groups. The first group was specified as the demonstration group (n = 8). In this group, fibrous ankylosis formation was shown experimentally. The rabbits in the second group, the treatment group (n = 16), were divided into 2 subgroups: gap arthroplasty, performed in group A (n = 8); and HAM, used as an interpositional arthroplasty material in group B (n = 8).
  
  
  RESULTS
  In all rabbits, the range of jaw movements and weight decreased after induction of ankylosis. After surgical treatment of fibrous ankylosis, the vertical, right, and left movements of the jaw and weights of rabbits increased immediately. The results were evaluated clinically, macroscopically, histologically, and radiologically. There was a statistically significant difference in the jaw movements between groups A and B (P < .05). All operated joints in group A showed fibrous adhesions across the gap, and the articular surface was irregular with osteophytes and bony islands on the joint surface. In group B, no fibrous adhesions were observed.
  
  
  CONCLUSIONS
  It was concluded that interpositional arthroplasty with HAM was superior to gap arthroplasty in the rabbit model in preventing ankylosis.
authors: Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey. drumuttuncel@gmail.com
authors: Umut
authors: U
authors: Tuncel
authors: G Y
authors: GY
authors: Ozgenel
mesh_terms: D000650:Amnion / Q000637:transplantation*; D000818:Animals; D000844:Ankylosis / Q000601:surgery; D001178:Arthroplasty / Q000379:methods*; D006801:Humans; D011817:Rabbits; D016059:Range of Motion, Articular; D055502:Secondary Prevention; D013704:Temporomandibular Joint / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013705:Temporomandibular Joint Disorders / Q000503:physiopathology / Q000601:surgery*