title: Application of umbilical cord serum eyedrops for recurrent corneal erosions.
abstract: OBJECTIVE
  To investigate the efficacy of umbilical cord serum eyedrops for the treatment of patients with recurrent corneal erosions.
  
  
  METHODS
  Thirty-five eyes of 35 patients with recurrent corneal erosions were studied. Eighteen eyes were treated with 20% umbilical cord serum eyedrops in addition to artificial tears (group A), and 17 eyes received artificial tears only (group B). Frequency of recurrence of corneal erosions was compared between the 2 groups.
  
  
  RESULTS
  The study included 17 male and 18 female patients. Mean age was 46.6 ± 13.4 years, and mean follow-up duration was 14.7 ± 2.5 months. No significant differences in age, sex, and follow-up duration were observed between the 2 groups. In group A, recurrence occurred 2 times in 3 eyes, 1 time in 3 eyes, and did not occur in 12 eyes. In group B, recurrence occurred 5 times in 1 eye, 3 times in 5 eyes, 2 times in 8 eyes, 1 time in 2 eyes, and did not occur in 1 eye. The mean frequency of recurrence was 0.50 ± 0.79 (0.04 ± 0.07 per month) in group A and 2.24 ± 1.09 (0.15 ± 0.08 per month) in group B (P < 0.01). No significant complications associated with serum use were observed.
  
  
  CONCLUSIONS
  In the treatment of recurrent corneal erosions, umbilical cord serum eyedrops may be effective in reducing the number of recurrences.
authors: Department of Ophthalmology and Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju, Korea. kcyoon@jnu.ac.kr
authors: Kyung-Chul
authors: KC
authors: Yoon
authors: Won
authors: W
authors: Choi
authors: In-Cheon
authors: IC
authors: You
authors: Jin
authors: J
authors: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003316:Corneal Diseases / Q000628:therapy*; D019573:Epithelium, Corneal / Q000187:drug effects / Q000473:pathology; D005260:Female; D005312:Fetal Blood; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D009883:Ophthalmic Solutions