title: Material characterization and computer model simulation of low density polyurethane foam used in a rodent traumatic brain injury model.
abstract: Computer models of the head can be used to simulate the events associated with traumatic brain injury (TBI) and quantify biomechanical response within the brain. Marmarou's impact acceleration rodent model is a widely used experimental model of TBI mirroring axonal pathology in humans. The mechanical properties of the low density polyurethane (PU) foam, an essential piece of energy management used in Marmarou's impact device, has not been fully characterized. The foam used in Marmarou's device was tested at seven strain rates ranging from quasi-static to dynamic (0.014-42.86 s⁻¹) to quantify the stress-strain relationships in compression. Recovery rate of the foam after cyclic compression was also determined through the periods of recovery up to three weeks. The experimentally determined stress-strain curves were incorporated into a material model in an explicit Finite Element (FE) solver to validate the strain rate dependency of the FE foam model. Compression test results have shown that the foam used in the rodent impact acceleration model is strain rate dependent. The foam has been found to be reusable for multiple impacts. However the stress resistance of used foam is reduced to 70% of the new foam. The FU_CHANG_FOAM material model in an FE solver has been found to be adequate to simulate this rate sensitive foam.
authors: Department of Biomedical Engineering, Wayne State University, 818 W Hancock Street, Detroit, MI 48201, USA. lzhang@wayne.edu
authors: Liying
authors: L
authors: Zhang
authors: Manish
authors: M
authors: Gurao
authors: King H
authors: KH
authors: Yang
authors: Albert I
authors: AI
authors: King
mesh_terms: D000818:Animals; D001930:Brain Injuries; D003198:Computer Simulation; D004195:Disease Models, Animal; D011140:Polyurethanes; D012377:Rodentia; D013045:Species Specificity; D013314:Stress, Mechanical
chemical_list: D011140:Polyurethanes; C028279:polyurethane foam