title: Characteristics of NDM-1-producing Escherichia coli isolates that belong to the successful and virulent clone ST131.
abstract: An NDM-1 carbapenemase-producing Escherichia coli isolate of sequence type 131 (ST131) that belonged to phylogenetic group B2 was obtained from a patient with a urinary tract infection who returned to the United States after a recent hospitalization while visiting India. NDM-1-producing E. coli ST131 had significantly more virulence factors than NDM-1-producing E. coli ST101, previously isolated from a patient in Canada. The presence of NDM β-lactamases in a very successful and virulent E. coli sequence type is of concern.
authors: Division of Microbiology, Calgary Laboratory Services, University of Calgary, Calgary, Alberta, Canada.
authors: Gisele
authors: G
authors: Peirano
authors: Paul C
authors: PC
authors: Schreckenberger
authors: Johann D D
authors: JD
authors: Pitout
mesh_terms: D000328:Adult; D004926:Escherichia coli / Q000145:classification* / Q000201:enzymology / Q000472:pathogenicity; D006801:Humans; D008297:Male; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000379:methods; D014552:Urinary Tract Infections / Q000382:microbiology; D014774:Virulence; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases; C552864:beta-lactamase NDM-1