title: Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters.
abstract: Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were made on the Wistar rat's dorsal skin. The efficiencies of laser-welding with different parameters were investigated. Incision-healing, histology examination, and a tensile strength test of incisions were recorded. Laser welding with the irradiance level of 15.9 W∕cm(2) for both 980 and 1064-nm lasers and exposure time of 5 s per spot in continuous wave mode yielded a more effective closure and healing with minimal thermal damage, faster recovery, and stronger apposition in comparison with a suturing technique. The conclusion is that skin welding with a combination of two near-infrared diode lasers can be a good candidate for incision closure, and further investigations are in progress for clinical use.
authors: Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, Changchun City, China.
authors: Liming
authors: L
authors: Hu
authors: Zhihua
authors: Z
authors: Lu
authors: Biao
authors: B
authors: Wang
authors: Junsheng
authors: J
authors: Cao
authors: Xiaobo
authors: X
authors: Ma
authors: Zhenhua
authors: Z
authors: Tian
authors: Zhijian
authors: Z
authors: Gao
authors: Li
authors: L
authors: Qin
authors: Xiaodong
authors: X
authors: Wu
authors: Yun
authors: Y
authors: Liu
authors: Lijun
authors: L
authors: Wang
mesh_terms: D000818:Animals; D062109:Dermatologic Surgical Procedures; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D055620:Optical Phenomena; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000473:pathology / Q000503:physiopathology; D013536:Suture Techniques; D013718:Tensile Strength; D058106:Wound Closure Techniques; D014945:Wound Healing