title: First serological evidence of West Nile virus activity in horses in Serbia.
abstract: West Nile virus (WNV), the most widely distributed flavivirus worldwide, has lately reemerged in Europe, causing worrisome outbreaks in humans and horses. Serological analysis by enzyme-linked immunoassay and plaque reduction neutralization test showed for the first time in Serbia that 12% of 349 horses presented specific neutralizing WNV antibodies, which in one case also cross-neutralized Usutu virus (USUV). This is the first time that anti-USUV high neutralizing antibody titers are reported in horses. All these data indicate that WNV and USUV are circulating in the region and advise on the convenience of implementing surveillance programs.
authors: Scientific Veterinary Institute "Novi Sad," Novi Sad, Serbia.
authors: Diana
authors: D
authors: Lupulovic
authors: Miguel A
authors: MA
authors: Martín-Acebes
authors: Sava
authors: S
authors: Lazic
authors: Julio
authors: J
authors: Alonso-Padilla
authors: Ana-Belén
authors: AB
authors: Blázquez
authors: Estela
authors: E
authors: Escribano-Romero
authors: Tamas
authors: T
authors: Petrovic
authors: Juan-Carlos
authors: JC
authors: Saiz
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005416:Flavivirus / Q000276:immunology* / Q000302:isolation & purification; D006736:Horses / Q000821:virology*; D007074:Immunoglobulin G / Q000097:blood; D055771:Serbia; D014902:West Nile virus / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G