title: [Primary angioplasty in women with ST-elevation myocardial infarction: in-hospital and long-term clinical results].
abstract: OBJECTIVE
  We evaluated in-hospital and long-term clinical results of female patients following primary angioplasty for ST-elevation myocardial infarction (STEMI), in comparison with male patients.
  
  
  METHODS
  We reviewed 2,644 patients (2,188 males, 456 females) who underwent primary angioplasty for STEMI between October 2003 and March 2008. Data on female patients concerning demographic and clinical characteristics, primary angioplasty results, in-hospital and 25-month follow-up results were compared with those of male patients.
  
  
  RESULTS
  Hypertension, diabetes mellitus, anemia, shock, and renal failure were more common in female patients, while smoking was more frequent in males (p<0.05). The mean age was higher in female patients (63.9±11.7 vs. 55.2±11.3 years, p<0.001). Females also presented with higher values of glucose, mean platelet volume, and platelet count, and lower hemoglobin and hematocrit values (p<0.05). The frequencies of multivessel disease and procedure failure were significantly higher, and pain-to-balloon time was significantly longer in females (p<0.05). Mortality associated with cardiovascular causes occurred in 148 patients (5.6%), being significantly higher in females (9.4% vs. 4.8%, p<0.001). In-hospital mortality, major cardiac events, stroke, cardiogenic shock, and major bleeding were more frequent in women (p<0.05). Long-term mortality rate was also significantly higher in females (10% vs. 4.5%, p<0.001). Multivariate analysis showed female gender as one of the independent predictors of mortality (odds ratio=1.75, 95% CI 1.02-2.99; p<0.04).
  
  
  CONCLUSIONS
  Female patients with STEMI undergoing primary angioplasty have a higher risk profile and poorer in-hospital and follow-up clinical results. Therefore, female patients should be treated more aggressively.
authors: Department of Cardiology, Siyami Ersek Cardiovascular Surgery Center, İstanbul, Turkey. erkayh@gmail.com
authors: Erkan
authors: E
authors: Ayhan
authors: Hüseyin
authors: H
authors: Uyarel
authors: Mehmet
authors: M
authors: Ergelen
authors: Gökhan
authors: G
authors: Ciçek
authors: Emre
authors: E
authors: Akkaya
authors: Zeki
authors: Z
authors: Günaydın
authors: Turgay
authors: T
authors: Işık
authors: Damirbek
authors: D
authors: Osmonov
authors: Ayça
authors: A
authors: Türer
authors: Ceyhan
authors: C
authors: Türkkan
authors: Mehmet
authors: M
authors: Bozbay
authors: Ahmet
authors: A
authors: Narin
mesh_terms: D000367:Age Factors; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000401:mortality / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors