title: Eyelid skin tightening: a novel 'Niche' for fractional CO₂ rejuvenation.
abstract: BACKGROUND
  The periorbital area is a barometer of chronologic and environmental age for which patients usually seek rejuvenation; fractional CO(2) laser plays a key role among the variety of available dermatologic treatments.
  
  
  OBJECTIVE
  The purpose of this study is to evaluate the efficacy and safety of Fractional CO(2) laser in eyelid tightening and periorbital wrinkles.
  
  
  METHODS
  Forty-five patients received a range of 2-3 treatments in the upper, lower eyelids and periorbital area with a fractional laser device. Photographs were taken before and after each treatment and 2 weeks, 4 weeks, 3 months, 6 months and 12 months after the final treatment. The results were judged by three dermatologists who had not taken part in the treatments.
  
  
  RESULTS
  One year after the last laser session, all patients showed global improvements in eyelid skin tightening: five patients (11.1%) achieved excellent improvement, 11 patients (24.5%) marked improvement, 15 patients (33.3%) moderate improvement and 14 subjects (31.1%) slight improvement. At the 1-year follow-up, the percentage of subjects with a lift in their eyebrows and consequently a widened palpebral fissure was 82.2 (37 patients), whereas 17.8% (eight patients) showed no eyebrow elevation.
  
  
  CONCLUSIONS
  Fractional CO(2) laser treatments allow dermatologists to achieve notable improvements in eyelid skin tightening, and eyebrow elevation safely and without significant side-effects.
authors: Department of Dermatology II, University of Florence, Florence, Italy.
authors: P
authors: P
authors: Bonan
authors: P
authors: P
authors: Campolmi
authors: G
authors: G
authors: Cannarozzo
authors: N
authors: N
authors: Bruscino
authors: A
authors: A
authors: Bassi
authors: S
authors: S
authors: Betti
authors: T
authors: T
authors: Lotti
mesh_terms: D002245:Carbon Dioxide; D005143:Eyelids / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D015595:Skin Aging
chemical_list: D002245:Carbon Dioxide