title: Trichosporon fungal arteritis causing rupture of vascular anastamosis after commercial kidney transplantation: a case report and review of literature.
abstract: This is a case report of a ruptured vascular anastomosis resulting from fungal arteritis in a commercial renal transplantation. The diagnosis was made quite early posttransplantation (at the 18th posttransplant day); this was proved by histopathologic examination and culture of the vessel wall,which showed Trichosporon fungal infection. The patient underwent operation for control of the bleeding and removal of the graft and of the diseased iliac vascular segment. On reviewing the literature, we found 17 reports of fungal arteritis in solid-organ transplant recipients; our case was the first one to report Trichosporon species as the causative agent. Infection could result from surgical or graft contamination or from preexistent infection in the patient. There is a consensus that the standard of care should include removal of the graft and the diseased iliac vascular segment with an appropriate vascular graft, because simple suturing of the disrupted infected anastomosis generally ends with disastrous recurrent rupture. A high index of suspicion is required to ensure both early diagnosis and appropriate treatment to prevent tragic loss of recipient life.
authors: Department of Surgery, Renal Transplantation, Hamad Medical Corporation, Doha, Qatar. riadhfadhil@yahoo.com
authors: R A S
authors: RA
authors: Fadhil
authors: H
authors: H
authors: Al-Thani
authors: Y
authors: Y
authors: Al-Maslamani
authors: O
authors: O
authors: Ali
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D001158:Arteries / Q000382:microbiology*; D001167:Arteritis / Q000382:microbiology* / Q000517:prevention & control; D006801:Humans; D007674:Kidney Diseases / Q000628:therapy; D016030:Kidney Transplantation / Q000379:methods*; D009181:Mycoses / Q000382:microbiology* / Q000517:prevention & control; D006435:Renal Dialysis; D014250:Trichosporon / Q000378:metabolism*; D058017:Vascular Grafting
chemical_list: D000935:Antifungal Agents