title: The effect of low-intensity pulsed ultrasound on the osseointegration of titanium dental implants.
abstract: Our aim was to record the effect of low-intensity pulsed ultrasound (LIPUS) on the osseointegration of endosseous dental implants in 10 New Zealand rabbits. One titanium implant with screw was inserted into the metaphyseal region of each femur and tibia in the knee joints of each rabbit, making a total of 40 implants. The area of one lateral knee joint, including implants, was irradiated with LIPUS for 10 min twice a day for 21 days. The other side acted as control, having been given "sham" irradiation. Two rabbits were killed at each of 0, 2, 4, 6, and 8 weeks after irradiation. A micro-computed tomogram (μCT), histological examination, and implant pull-out test were used to judge the reactions of the bone to the titanium implant. Histological and μCT examinations showed that osseointegration of the implants on the LIPUS-treated side happened earlier and more effectively than on the control side. The mechanical test showed that the maximal axial pull-out strength of the implants on the LIPUS-treated side was greater than that on the control side. We conclude that LIPUS has the potential to accelerate the osseointegration of dental implants.
authors: Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Lintong Aviation Medical Evaluation and Training Center of Chinese Air Force, PR China.
authors: Qing
authors: Q
authors: Liu
authors: Xin
authors: X
authors: Liu
authors: Baolin
authors: B
authors: Liu
authors: Kaijin
authors: K
authors: Hu
authors: Xiaodong
authors: X
authors: Zhou
authors: Yuxiang
authors: Y
authors: Ding
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000502:physiology; D001861:Bone Regeneration / Q000502:physiology; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D005269:Femur / Q000473:pathology / Q000601:surgery; D006614:Hindlimb / Q000601:surgery; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D016348:Osseointegration / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits; D013314:Stress, Mechanical; D013977:Tibia / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014025:Titanium / Q000737:chemistry; D014465:Ultrasonics / Q000295:instrumentation; D055114:X-Ray Microtomography / Q000379:methods
chemical_list: D015921:Dental Implants; D003764:Dental Materials; D014025:Titanium