title: Chlamydia persistence -- a tool to dissect chlamydia--host interactions.
abstract: Under stress, chlamydiae can enter a non-infectious but viable state termed persistence. In the absence of a tractable genetic system, persistence induction provides an important experimental tool with which to study these fascinating organisms. This review will discuss examples of: i) persistence studies that have illuminated critical chlamydiae/host interactions; and ii) novel persistence models that will do so in the future.
authors: Department of Microbiology, East Tennessee State University, James H. Quillen College of Medicine, Johnson City, TN 37614-1708, USA. schoborg@etsu.edu.
authors: R V
authors: RV
authors: Schoborg
mesh_terms: D000818:Animals; D002460:Cell Line; D002689:Chlamydia / Q000254:growth & development* / Q000472:pathogenicity; D002690:Chlamydia Infections / Q000473:pathology*; D054884:Host-Pathogen Interactions; D006801:Humans; D007371:Interferon-gamma / Q000378:metabolism; D008954:Models, Biological; D010641:Phenotype; D058913:Purinergic Agonists / Q000378:metabolism; D012906:Smoke / Q000009:adverse effects; D014026:Nicotiana / Q000633:toxicity; D018523:Tropism
chemical_list: D058913:Purinergic Agonists; D012906:Smoke; D007371:Interferon-gamma