title: CUORE project: implementation of the 10-year risk score.
abstract: OBJECTIVE
  The Italian national prevention plan 2005-2008 included 10-year cardiovascular risk (10-CR) assessment of the general population aged 35-69 years using the CUORE project risk score. General practitioners (GPs) were encouraged to collect data on risk factors and 10-CR and to contribute to the Cardiovascular Risk Observatory (CRO). The aim is to demonstrate feasibility and effectiveness of 10-CR assessment as a first step to implement primary preventive actions at the individual level.
  
  
  METHODS
  Data were collected using CUORE.EXE software, easily and freely downloadable by GPs from the CUORE project website (www.cuore.iss.it). CRO provides a web platform to analyse and compare data on 10-CR and risk factors at regional and national levels with the aim of supporting health policy decision processes.
  
  
  RESULTS
  From January 2007 to May 2010, 2,858 GPs downloaded cuore.exe; 139,269 CR assessments on 117,345 persons were sent to CRO. CR mean was 3.0% in women, 8.3% in men; 30% of men and 65% of women were at lower risk (CR < 3%), 9.2% of men and 0.4% of women were at high risk (CR ≥ 20%). Among those with at least two risk assessments (n = 5,948), 8% (95% CI 7-9%) shifted to a lower risk class after 1 year. Systolic blood pressure mean levels decreased by 1.6 mmHg (95% CI 1.2-2.1 mmHg), diastolic blood pressure by 0.9 mmHg (95% CI 0.5-1.3 mmHg), total cholesterol by 5.6 mg/dl (95% CI 4.3-6.8 mg/dl), and smokers prevalence by 3.5% (95% CI 2.5-4.6%); high-density lipoprotein cholesterol increased in women by 1 mg/dl (95% CI 0.5-1.4 mg/dl).
  
  
  CONCLUSIONS
  Data demonstrate that 10-CR assessment can be the first step to implement preventive actions in primary care.
authors: National Centre for Epidemiology, Surveillance and Health Promotion, National Health Institute, Rome, Italy.
authors: Luigi
authors: L
authors: Palmieri
authors: Rita
authors: R
authors: Rielli
authors: Luca
authors: L
authors: Demattè
authors: Chiara
authors: C
authors: Donfrancesco
authors: Paola
authors: P
authors: Ciccarelli
authors: Patrizia
authors: P
authors: De Sanctis Caiola
authors: Francesco
authors: F
authors: Dima
authors: Cinzia
authors: C
authors: Lo Noce
authors: Ovidio
authors: O
authors: Brignoli
authors: Alfredo
authors: A
authors: Cuffari
authors: Simona
authors: S
authors: Giampaoli
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D003661:Decision Support Techniques; D050171:Dyslipidemias / Q000150:complications* / Q000453:epidemiology / Q000628:therapy*; D005240:Feasibility Studies; D005260:Female; D058006:General Practice; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology / Q000628:therapy*; D020407:Internet; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011322:Primary Prevention / Q000706:statistics & numerical data; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology; D012984:Software; D013997:Time Factors