title: PredictABEL: an R package for the assessment of risk prediction models.
abstract: The rapid identification of genetic markers for multifactorial diseases from genome-wide association studies is fuelling interest in investigating the predictive ability and health care utility of genetic risk models. Various measures are available for the assessment of risk prediction models, each addressing a different aspect of performance and utility. We developed PredictABEL, a package in R that covers descriptive tables, measures and figures that are used in the analysis of risk prediction studies such as measures of model fit, predictive ability and clinical utility, and risk distributions, calibration plot and the receiver operating characteristic plot. Tables and figures are saved as separate files in a user-specified format, which include publication-quality EPS and TIFF formats. All figures are available in a ready-made layout, but they can be customized to the preferences of the user. The package has been developed for the analysis of genetic risk prediction studies, but can also be used for studies that only include non-genetic risk factors. PredictABEL is freely available at the websites of GenABEL ( http://www.genabel.org ) and CRAN ( http://cran.r-project.org/).
authors: Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
authors: Suman
authors: S
authors: Kundu
authors: Yurii S
authors: YS
authors: Aulchenko
authors: Cornelia M
authors: CM
authors: van Duijn
authors: A Cecile J W
authors: AC
authors: Janssens
mesh_terms: D003627:Data Interpretation, Statistical; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study / Q000706:statistics & numerical data; D006801:Humans; D011237:Predictive Value of Tests; D018570:Risk Assessment / Q000379:methods*; D012984:Software
chemical_list: D005819:Genetic Markers