title: On the 'rate of aging' in heterogeneous populations.
abstract: It is well known that the rate of aging is constant for populations described by the Gompertz law of mortality. However, this is true only when a population is homogeneous. In this note, we consider the multiplicative frailty model with the baseline distribution that follows the Gompertz law and study the impact of heterogeneity on the rate of aging in this population. We show that the rate of aging in this case is a function of age and that it increases in (calendar) time when the baseline mortality rate decreases.
authors: Department of Mathematical Statistics, University of the Free State, South Africa. FinkelM@ufs.ac.za
authors: Maxim
authors: M
authors: Finkelstein
mesh_terms: D000375:Aging; D008954:Models, Biological; D016016:Proportional Hazards Models