title: A prospective metal ion study of large-head metal-on-metal bearing: a matched-pair analysis of hip resurfacing versus total hip replacement.
abstract: The current study measured ion release among large-head metal-on-metal hip bearings. Twenty-six patients with a modular, Profemur® TL with A-Class® big femoral head total hip replacement were matched (gender, femoral size, BMI) with a group of 26 patients with the Conserve® Plus implant hip resurfacing. Compared with HR patients, THR patients had higher median serum cobalt ion levels at 6 months (3.26 vs 1.12 μg/L, P = .002) 1 year (4.51 vs 1.02, P = .002), and 2 years (3.77 vs 1.22, P<.001) following surgery. No differences in chromium ions were observed. Further research is required to determine the clinical significance of elevated serum cobalt ions.
authors: The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada. pbeaule@ottawahospital.on.ca
authors: Paul E
authors: PE
authors: Beaulé
authors: Paul R
authors: PR
authors: Kim
authors: Amre
authors: A
authors: Hamdi
authors: Anna
authors: A
authors: Fazekas
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D002857:Chromium; D003035:Cobalt; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007477:Ions; D008297:Male; D016555:Matched-Pair Analysis; D011446:Prospective Studies; D011474:Prosthesis Design
chemical_list: D007477:Ions; D002857:Chromium; D003035:Cobalt