title: Supplementation with estradiol-17β improves porcine oocyte maturation and subsequent embryo development.
abstract: Metaphase II oocyte production was significantly increased by treatment with E(2) during the first half of the total in vitro maturation (IVM) period, which was further evidenced by an increase in monospermic fertilization, blastocyst formation, or blastomere viability of IVF- or somatic cell nuclear transfer-derived embryos. Thus, we concluded that transient E(2) supplementation could improve the IVM rate and subsequent developmental competence in pigs.
authors: National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk, Republic of Korea.
authors: Ji-Su
authors: JS
authors: Kim
authors: Bong-Seok
authors: BS
authors: Song
authors: Sang-Rae
authors: SR
authors: Lee
authors: Seung-Bin
authors: SB
authors: Yoon
authors: Jae-Won
authors: JW
authors: Huh
authors: Sun-Uk
authors: SU
authors: Kim
authors: Ekyun
authors: E
authors: Kim
authors: Sang-Hyun
authors: SH
authors: Kim
authors: Young-Kug
authors: YK
authors: Choo
authors: Deog-Bon
authors: DB
authors: Koo
authors: Kyu-Tae
authors: KT
authors: Chang
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000187:drug effects* / Q000502:physiology; D016203:CDC2 Protein Kinase / Q000378:metabolism; D002478:Cells, Cultured; D046149:Embryo Culture Techniques; D047108:Embryonic Development / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D005307:Fertilization in Vitro; D008540:Meiosis / Q000187:drug effects; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000378:metabolism; D053652:Nuclear Transfer Techniques; D009865:Oocytes / Q000187:drug effects* / Q000502:physiology; D010766:Phosphorylation; D013552:Swine; D013997:Time Factors
chemical_list: D004958:Estradiol; D016203:CDC2 Protein Kinase; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3