title: Switching among antipsychotics--focus on side effects.
abstract: Depression is a disorder held responsible for high morbidity in the overall population. Causes of depression vary, but lifestyle and stress can greatly contribute to its morbidity. Consumption of antidepressants is showing a trend in the economically developed countries. Apart from antidepressants, the treatment of depression can consist of other psychopharmaca. Depending on the severity of a disorder, that is - of psychotic symptoms, antipsychotics can be introduced in the treatment. Among those atypical antipsychotics have an advantage. This paper will illustrate a course of treatment of a female patient, diagnosed with psychotic depression and treated with antipsychotics (i.e. olanzapine, ziprasidone), to which she developed side effects. To each of the antypsychotics the patient developed side effechts, causing in prolonged treatment and affected its course.
authors: University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Rijeka, Croatia. ruzic.klementina@gmail.com
authors: Klementina
authors: K
authors: Ružić
authors: Elizabeta
authors: E
authors: Dadić-Hero
authors: Tanja
authors: T
authors: Grahovac
authors: Vladimir
authors: V
authors: Sabljić
authors: Tanja
authors: T
authors: Kosec
authors: Rajna
authors: R
authors: Knez
mesh_terms: D000341:Affective Disorders, Psychotic / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000009:adverse effects / Q000627:therapeutic use; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D003875:Drug Eruptions / Q000175:diagnosis; D057915:Drug Substitution / Q000523:psychology*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D000077152:Olanzapine; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use; D011537:Pruritus / Q000139:chemically induced; D013469:Sulpiride / Q000009:adverse effects / Q000627:therapeutic use; D013844:Thiazoles / Q000009:adverse effects / Q000627:therapeutic use; D015430:Weight Gain / Q000187:drug effects
chemical_list: D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; D001569:Benzodiazepines; C092292:ziprasidone; D013469:Sulpiride; D000077152:Olanzapine