title: Disordered gambling as defined by the Diagnostic and Statistical Manual of Mental Disorders and the South Oaks Gambling Screen: evidence for a common etiologic structure.
abstract: In a previous article, we demonstrated in a large twin study that disordered gambling (DG), as defined by the Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV), ran in families, that about half of the variation in liability for DG was due to familial factors, and that all of this was explained by shared genetic rather than shared environmental influences (Slutske, Zhu, Meier, & Martin, 2010). The purpose of the present study is to extend this work to include an alternative conceptualization of DG that is provided by the South Oaks Gambling Screen (SOGS) item set in order to (a) compare the magnitude of the familial resemblance obtained when using the two definitions of DG (based on the DSM-IV and the SOGS), (b) examine the extent to which the 2 definitions tap the same underlying sources of genetic and environmental variation, and (c) examine whether the same results will be obtained among men and women. The results of bivariate twin model-fitting analyses suggested that DG, as defined by the DSM-IV and the SOGS, substantially overlapped at the etiologic level among both men and women, which supports the construct validity of both the DSM and the SOGS conceptualizations of DG. This study highlights the utility of twin studies for appraising the validity of the diagnostic nomenclature.
authors: Department of Psychological Sciences, 210 McAlester Hall, University of Missouri, Columbia, Missouri 65211, USA. slutskew@missouri.edu
authors: Wendy S
authors: WS
authors: Slutske
authors: Gu
authors: G
authors: Zhu
authors: Madeline H
authors: MH
authors: Meier
authors: Nicholas G
authors: NG
authors: Martin
mesh_terms: D000328:Adult; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004200:Diseases in Twins / Q000175:diagnosis / Q000209:etiology*; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005715:Gambling / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D012042:Registries; D012931:Social Environment; D014427:Twins