title: Masked hypertension is "unmasked" by low-intensity exercise blood pressure.
abstract: OBJECTIVE
  Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP) taken under resting conditions. We sought to determine if MH could be identified from BP taken during a single bout of low-intensity exercise.
  
  
  METHODS
  BP was recorded at rest and during brief low-level cycling exercise (60-70% of age-predicted maximal heart rate) in 75 untreated subjects with a hypertensive response to exercise (aged 54 ± 9 years). All subjects underwent 24-h ambulatory BP monitoring (ABPM) and MH was defined as clinic BP < 140/90 mmHg and ABPM BP ≥ 130/80 mmHg.
  
  
  RESULTS
  There were 42 (56%) patients with MH, and at rest systolic (SBP) was higher in subjects with MH compared with those without MH (127 ± 9 vs 120 ± 9 mmHg; p < 0.05). During exercise, MH subjects had significantly higher SBP (188 ± 22 vs 168 ± 15 mmHg; p < 0.05), with a greater change from baseline (61 ± 21 vs 48 ± 15 mmHg; p < 0.05). Low-level exercise SBP was independently associated with MH, and if ≥ 175 mmHg, identified MH with 74% sensitivity and 67% specificity (p < 0.001).
  
  
  CONCLUSIONS
  MH can be identified in untreated individuals from low-intensity exercise SBP. Further research on the diagnostic value of BP during early phases of exercise stress testing is needed.
authors: Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia.
authors: Martin G
authors: MG
authors: Schultz
authors: James L
authors: JL
authors: Hare
authors: Thomas H
authors: TH
authors: Marwick
authors: Michael
authors: M
authors: Stowasser
authors: James E
authors: JE
authors: Sharman
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D005080:Exercise Test / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D059468:Masked Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged; D012680:Sensitivity and Specificity