title: [Computerized cardiotocography and short-term variation in management of obstetric cholestasis: a useful tool?].
abstract: OBJECTIVE
  To evaluate active management of obstetric cholestasis by comparing correlation between bile acid concentrations and computerized cardiotocography (Short-term variation [STV]).
  
  
  METHODS
  Retrospective analytic study about 51 obstetric cholestasis between January 2001 and August 2009. Demographic characteristics, bile acid concentrations and STV data were recorded since diagnosis to pregnancy with evaluation of fetal outcome.
  
  
  RESULTS
  There were no statistical correlation between bile acid concentrations, STV data and fetal outcome. Patients with cholestasis diagnosed in second trimester delivered 12 days earlier than cholestasis diagnosed in third trimester (p=0.0012). Delivery before 37 weeks was found in 37.2% of cases. There were no perinatal deaths. Sixty percent had a recurrent obstetric cholestasis.
  
  
  CONCLUSIONS
  Further works are necessary to study the exact pathogeny of obstetric cholestasis in order to determinate the best surveillance.
authors: Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Nord, CHU de Saint-Étienne, avenue Albert-Raimond, 42000 Saint-Étienne, France.
authors: E
authors: E
authors: Poncelet
authors: B
authors: B
authors: Trombert
authors: M-N
authors: MN
authors: Varlet
authors: S
authors: S
authors: Cochin
authors: H
authors: H
authors: Patural
authors: G
authors: G
authors: Teyssier
authors: P
authors: P
authors: Seffert
authors: G
authors: G
authors: Chêne
mesh_terms: D000328:Adult; D001647:Bile Acids and Salts / Q000097:blood; D015148:Cardiotocography / Q000379:methods*; D002779:Cholestasis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005313:Fetal Death / Q000209:etiology / Q000517:prevention & control; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy*; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000209:etiology / Q000517:prevention & control; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D001647:Bile Acids and Salts