title: An unusual case of exclusive liver metastases from adenoid cystic carcinoma of the submandibular gland: a role for surgery? Report of a case.
abstract: Adenoid cystic carcinoma (ACC) is a relatively rare tumor of the salivary glands, accounting for approximately 5%-10% of all salivary gland tumors. An important feature of ACCs is the long clinical course with a high rate of distant metastases, with an incidence of more than 40% for ACC of submandibular glands. The preferential sites of metastases are the lung and bone, followed by the brain and liver. Most liver metastases are derived from nonparotid ACCs, and the presentation is often related to local recurrence or metastases to other organs. We herein report the case of a patient with liver metastases treated by a hepatectomy, which occurred 18 months after the primary resection of an ACC of the submandibular gland. We furthermore review the literature concerning the management of these tumors.
authors: Department of General Surgery, II School of Medicine, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa, Rome, Italy.
authors: Genoveffa
authors: G
authors: Balducci
authors: Andrea
authors: A
authors: Sagnotta
authors: Mirko
authors: M
authors: Muroni
authors: Claudio
authors: C
authors: Cacchi
authors: Alberto
authors: A
authors: D'Amato
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003528:Carcinoma, Adenoid Cystic / Q000556:secondary* / Q000601:surgery*; D017809:Fatal Outcome; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013365:Submandibular Gland Neoplasms / Q000473:pathology* / Q000601:surgery*; D014057:Tomography, X-Ray Computed