title: Using integrated mixed methods to develop behavioral measures of factors associated with microbicide acceptability.
abstract: Our current understanding of factors associated with microbicide acceptability and consistent use typically has been derived from separate and distinct qualitative or quantitative studies. Specifically, rarely have investigators used mixed methods to both develop and validate behavioral measures. We utilized an integrated mixed methods design, including qualitative metasyntheses, cognitive interviews and expert reviews, psychometric evaluation, and confirmatory qualitative analyses of the correspondence between quantitative items and original qualitative data to develop and validate measures of factors associated with microbicide acceptability and use. We describe this methodology and use the development of the Relationship Context Scale to illustrate it. As a result of independent confirmatory analyses of qualitative passages corresponding to survey items, we demonstrated that items from the same subscales are frequently double coded within a particular textual passage, and thematically related, suggesting associations that resulted in a unique factor structure within the subscale. This integrated mixed method design was critical to the development of this psychometrically validated behavioral measure, and could serve as a model for future measure development.
authors: The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA. kmorrow@lifespan.org
authors: Kathleen M
authors: KM
authors: Morrow
authors: Rochelle K
authors: RK
authors: Rosen
authors: Liz
authors: L
authors: Salomon
authors: Cynthia
authors: C
authors: Woodsong
authors: Lawrence
authors: L
authors: Severy
authors: Joseph L
authors: JL
authors: Fava
authors: Sara
authors: S
authors: Vargas
authors: Candelaria
authors: C
authors: Barroso
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D000282:Administration, Intravaginal; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D005163:Factor Analysis, Statistical; D005260:Female; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D010342:Patient Acceptance of Health Care / Q000523:psychology*
chemical_list: D000890:Anti-Infective Agents