title: Efficacy of endoscopic therapy for gastrointestinal bleeding from Dieulafoy's lesion.
abstract: OBJECTIVE
  To investigate the endoscopic hemostasis for gastrointestinal bleeding due to Dieulafoy's lesion.
  
  
  METHODS
  One hundred and seven patients with gastrointestinal bleeding due to Dieulafoy's lesion were treated with three endoscopic hemostasis methods: aethoxysklerol injection (46 cases), endoscopic hemoclip hemostasis (31 cases), and a combination of hemoclip hemostasis with aethoxysklerol injection (30 cases).
  
  
  RESULTS
  The rates of successful hemostasis using the three methods were 71.7% (33/46), 77.4% (24/31) and 96.7% (29/30), respectively, with significant differences between the methods (P < 0.05). Among those who had unsuccessful treatment with aethoxysklerol injection, 13 were treated with hemoclip hemostasis and 4 underwent surgical operation; 9 cases were successful in the injection therapy. Among the cases with unsuccessful treatment with hemoclip hemostasis, 7 were treated with injection of aethoxysklerol and 3 cases underwent surgical operation; 4 cases were successful in the treatment with hemoclip hemostasis. Only 1 case had unsuccessful treatment with a combined therapy of hemoclip hemostasis and aethoxysklerol injection, and surgery was then performed. No serious complications of perforation occurred in the patients whose bleeding was treated with the endoscopic hemostasis, and no re-bleeding was found during a 1-year follow-up.
  
  
  CONCLUSIONS
  The combined therapy of hemoclip hemostasis with aethoxysklerol injection is the most effective method for gastrointestinal bleeding due to Dieulafoy's lesion.
authors: Department of Gastroenterology, Yantai Yu Huang Ding Hospital, Yantai, Shandong Province, China.
authors: Jun
authors: J
authors: Cui
authors: Liu-Ye
authors: LY
authors: Huang
authors: Yun-Xiang
authors: YX
authors: Liu
authors: Bo
authors: B
authors: Song
authors: Long-Zhi
authors: LZ
authors: Yi
authors: Ning
authors: N
authors: Xu
authors: Bo
authors: B
authors: Zhang
authors: Cheng-Rong
authors: CR
authors: Wu
mesh_terms: D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000150:complications* / Q000628:therapy; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D005773:Gastroscopy / Q000379:methods; D016558:Hemostasis, Endoscopic / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000494:pharmacology
chemical_list: D000077423:Polidocanol; D011092:Polyethylene Glycols