title: Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan.
abstract: BACKGROUND
  The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007.
  
  
  METHODS
  The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the system of the Internet Data and Information Center for Medical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008.
  
  
  RESULTS
  Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%).
  
  
  CONCLUSIONS
  In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.
authors: Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
authors: Hitoshi
authors: H
authors: Sugiyama
authors: Hitoshi
authors: H
authors: Yokoyama
authors: Hiroshi
authors: H
authors: Sato
authors: Takao
authors: T
authors: Saito
authors: Yukimasa
authors: Y
authors: Kohda
authors: Shinichi
authors: S
authors: Nishi
authors: Kazuhiko
authors: K
authors: Tsuruya
authors: Hideyasu
authors: H
authors: Kiyomoto
authors: Hiroyuki
authors: H
authors: Iida
authors: Tamaki
authors: T
authors: Sasaki
authors: Makoto
authors: M
authors: Higuchi
authors: Motoshi
authors: M
authors: Hattori
authors: Kazumasa
authors: K
authors: Oka
authors: Shoji
authors: S
authors: Kagami
authors: Michio
authors: M
authors: Nagata
authors: Tetsuya
authors: T
authors: Kawamura
authors: Masataka
authors: M
authors: Honda
authors: Yuichiro
authors: Y
authors: Fukasawa
authors: Atsushi
authors: A
authors: Fukatsu
authors: Kunio
authors: K
authors: Morozumi
authors: Norishige
authors: N
authors: Yoshikawa
authors: Yukio
authors: Y
authors: Yuzawa
authors: Seiichi
authors: S
authors: Matsuo
authors: Yutaka
authors: Y
authors: Kiyohara
authors: Kensuke
authors: K
authors: Joh
authors: Takashi
authors: T
authors: Taguchi
authors: Hirofumi
authors: H
authors: Makino
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005922:Glomerulonephritis, IGA / Q000453:epidemiology / Q000473:pathology; D015433:Glomerulonephritis, Membranous / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D007223:Infant; D020407:Internet; D007564:Japan / Q000453:epidemiology; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000453:epidemiology / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000453:epidemiology / Q000473:pathology; D012042:Registries