title: [Asbestos-related lung cancer].
abstract: Lung cancer is the leading cause of tumour death and a large percentage of it is associated with tobacco smoking. Epidemiology has shown that asbestos cumulative exposures increase the risk of lung cancer to a variable extent, depending on the manufacturing process and the specific job. The risk appears relatively small (< or = 2) and is detectable after massive exposures only. Clinical diagnosis of asbestos-related lung cancer is based upon medical history (exposures > 25 ff.ml years double the risk), possible lung fibrosis and counts of asbestos bodies and fibers in bronchoalveolar lavage and lung tissues. Pleural plaques do not correlate with the cumulative exposures that are associated with lung cancer. The multiplicative interaction between smoke and asbestos is only detectable when the risk associated with asbestos exposure is increased, i.e. after high exposures.
authors: Università di Padova, Dipartimento di Medicina Ambientale e Sanità Pubblica, Padova, Italy.
authors: M
authors: M
authors: Lotti
mesh_terms: D001194:Asbestos / Q000009:adverse effects*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012907:Smoking / Q000009:adverse effects
chemical_list: D001194:Asbestos