title: The unique correlation between anti-mutagenicity of human saliva and change in body weight.
abstract: The purpose of this study was to investigate the effect of weight reduction on the anti-mutagenicity of human saliva. Subjects were 16 male college judo players. The anti-mutagenicity of the saliva was measured using the umu test. There was an inhibiting effect of the saliva on the mutagenicity of AF-2. However, a modifying effect of the saliva on Trp-P-1 was not observed. On the day before a competition and 7 days after the competition, the inhibiting capacity of the saliva for the mutagenicity of AF-2 decreased and increased in two non-weight reduction and two weight reduction groups, respectively.However, on the day before the competition, the changed body weights (r=-0.77, p<0.01) and BMI (r=-0.77, p<0.01) were significantly correlated with that of the inhibiting capacity of the saliva for the mutagenicity of AF-2. In addition, the BMI at 20 days before the competition was not significantly but markedly correlated with it (r=0.50, p=0.057). At 7 days after the competition, however, these correlations were not found.These findings suggest a unique correlation between the anti-mutagenicity of human saliva and body weight or BMI.
authors: Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, 565-0871, Suita, Osaka, Japan.
authors: M
authors: M
authors: Toda
authors: K
authors: K
authors: Morimoto
authors: S
authors: S
authors: Nakamura
authors: T
authors: T
authors: Umeda
authors: S
authors: S
authors: Nakaji
authors: K
authors: K
authors: Sugawara