title: Copper-catalyzed annulative amination of ortho-alkynylphenols with hydroxylamines: synthesis of 3-aminobenzofurans by umpolung amination strategy.
abstract: A room temperature copper-catalyzed annulative amination of ortho-alkynylphenols with electrophilic amination reagents, O-acylated hydroxylamines, proceeds efficiently to provide the corresponding 3-aminobenzofurans of biological and pharmaceutical interest.
authors: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. kitamura@cc.saga-u.ac.jp
authors: Koji
authors: K
authors: Hirano
authors: Tetsuya
authors: T
authors: Satoh
authors: Masahiro
authors: M
authors: Miura
mesh_terms: D000586:Amination; D001572:Benzofurans / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D019811:Hydroxylamine / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D010636:Phenols; D019811:Hydroxylamine; D003300:Copper