title: Combined correction of axial hyperopia and astigmatism using the light adjustable intraocular lens.
abstract: OBJECTIVE
  To determine whether residual spherical and cylindrical errors could be corrected postoperatively using spatially profiled UV light irradiation in patients with axial hyperopia undergoing cataract surgery and implantation of a light adjustable, silicone intraocular lens (LAL).
  
  
  METHODS
  We conducted a prospective, nonrandomized clinical trial. The LALs were implanted in eyes with axial lengths <22.20 mm and were treated with a spatial intensity profile delivered by a digital light delivery device to induce a targeted spherical and cylindrical refractive change postoperatively. Once the desired correction was achieved, the LAL was treated again to lock-in the lens power.
  
  
  METHODS
  We studied 15 eyes of 15 patients with axial hyperopia.
  
  
  METHODS
  The manifest refraction, uncorrected visual acuity (UCVA), and best spectacle-corrected visual acuity (BCVA) were determined with follow-up time of 12 months to determine the achieved refractive corrections and their stability.
  
  
  METHODS
  We measured UCVA, BCVA, achieved versus targeted refractive outcome, and refractive stability with a follow-up time of 12 months.
  
  
  RESULTS
  Of 15 eyes, 14 (93%) achieved ± 0.5 diopters (D), and 10 (67%) were within ± 0.25 D of the targeted refractive adjustment up to 12 months postoperative follow-up. Only 1 treated eye showed a change of 0.38 D in manifest spherical equivalent refraction, the remaining 14 eyes showed <0.25 D change between 1 month post lock-in, and at the 3-, 6-, and 12-month postoperative visits.
  
  
  CONCLUSIONS
  The light-adjustable lens is a promising technology with the potential to reduce the rate of postoperative refractive surprises up to 2 D of spherical and cylindrical errors after cataract surgery. Postoperative refractive errors were successfully corrected with precision and significant improvement in UCVA and without compromising BCVA using the light-adjustable intraocular lens technology. The data demonstrate the stability of the achieved refractive change after the adjustment and lock-in procedures.
authors: Center for Vision Science, Ruhr University Eye Clinic, Bochum, Germany. fritz.hengerer@kk-bochum.de
authors: Fritz H
authors: FH
authors: Hengerer
authors: Werner W
authors: WW
authors: Hütz
authors: H Burkhard
authors: HB
authors: Dick
authors: Ina
authors: I
authors: Conrad-Hengerer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001251:Astigmatism / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D004867:Equipment Design; D005139:Eyeglasses; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000009:adverse effects; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics; D011184:Postoperative Period; D011446:Prospective Studies; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity