title: Inhibition of Acinetobacter baumannii biofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit.
abstract: A polymeric composite containing a 2-aminoimidazole derivative was synthesized. It was found that this polymer was resistant to biofilm colonization by Acinetobacter baumannii, no leaching of the 2-aminoimidazole derivative was observed after 2 weeks of treatment with deionized water, and the resulting polymer was not hemolytic.
authors: North Carolina State University, Department of Chemistry, Raleigh, North Carolina, 27695-8204, USA.
authors: Lingling
authors: L
authors: Peng
authors: Joseph
authors: J
authors: DeSousa
authors: Zhaoming
authors: Z
authors: Su
authors: Bruce M
authors: BM
authors: Novak
authors: Alexander A
authors: AA
authors: Nevzorov
authors: Eva R
authors: ER
authors: Garland
authors: Christian
authors: C
authors: Melander
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000254:growth & development; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000494:pharmacology; D018441:Biofilms / Q000187:drug effects; D005840:Gentian Violet / Q000032:analysis; D007093:Imidazoles / Q000138:chemical synthesis / Q000494:pharmacology; D008689:Methacrylates / Q000737:chemistry; D011108:Polymers / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D007093:Imidazoles; D008689:Methacrylates; D011108:Polymers; C014973:2-aminoimidazole; D005840:Gentian Violet