title: [Effect of integrated traditional Chinese and Western medicine on Th1/Th2 cytokines level in children with asthma].
abstract: OBJECTIVE
  To discuss the effect of integrated traditional Chinese and Western medicine on Th1/Th2 cytokines level in children with asthma.
  
  
  METHODS
  Children with asthma were randomly divided into control group and treatment group. The control group was given Montelukast Sodium tablets for 4 mg (2-5 years old) or 5 mg (6-14 years old), once every night before sleeping. At the same time, the treatment group was given Pingchuan water decoction additionally for one tie per day, in four to six-divided doses for eight weeks. On the other hand, groups of health children were selected as blank control. Before and after treatment, the level of IL-4, IL-13 and IFN-gamma were detected by elisa from 3 mL of venous blood.
  
  
  RESULTS
  Before treatment, IL-4 and IL-13 in two groups were obviously higher than healthy group, but IFN-gamma was lower (P < 0.01, P < 0.05). After eight weeks, IL-4 and IL-13 in treatment group went down, but IFN-gamma increased. And there were significant different compared with the control group (P < 0.05).
  
  
  CONCLUSIONS
  Treating children asthma by integrated traditional Chinese and western medicine can obviously reduce IL4 and IL-13, increase IFN-gamma, and therefore lighten the airway inflammation, prevent asthma attacks effectively.
authors: Medical College of Jinhua College of Profession and Technology, Jinhua 321017, China. ghh53021@163.com
authors: Guohua
authors: G
authors: Hu
authors: Ming
authors: M
authors: Lin
authors: Yiji
authors: Y
authors: Chang
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism*; D002648:Child; D016207:Cytokines / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D018417:Th1 Cells / Q000187:drug effects / Q000378:metabolism*; D018418:Th2 Cells / Q000187:drug effects / Q000378:metabolism*; D019366:Western World
chemical_list: D016207:Cytokines