title: Ellagic acid promoted biomimetic synthesis of shape-controlled silver nanochains.
abstract: In this work, ellagic acid (EA), a naturally occurring plant polyphenol, was utilized for the biomimetic synthesis of silver (Ag) nanoparticles, which over a period of time formed extended branched nanochains of hexagonal-shaped silver nanoparticles. It was found that EA not only has the capability of reducing silver ions, resulting in the formation of Ag nanoparticles, due to its extended polyphenolic system, but also appears to recognize and affect the Ag nanocrystal growth on the (111) face, leading to the formation of hexagon-shaped Ag nanocrystals. Initially, various Ag nanocrystal shapes were observed; however, over a longer period of time, a majority of hexagonal-shaped nanocrystals were formed. Although the exact mechanism of formation of the nanocrystals is not known, it appears that EA attaches to the silver nuclei, leading to lower surface energy of the (111) face. Further, the nanocrystals fuse together, forming interfaces among the aggregates, and, with time, those interfaces become lesser, and the nanoparticles merge together and share the same single crystallographic orientation, which leads to the formation of long elongated chains of hexagonal nanoparticles. This biomimetic approach may be developed as a green synthetic method to prepare building blocks with tunable properties for the development of nanodevices. Further, we explored the antibacterial properties and found that the tandem of EA-Ag nanochains substantially enhanced the antibacterial properties of both gram-positive and gram-negative bacteria compared to silver nanoparticles or EA alone. Additionally, the materials were also utilized for imaging of mammalian NRK (normal rat kidney) cells.
authors: Department of Chemistry, Fordham University, Bronx, NY 10458, USA.
authors: Stacey N
authors: SN
authors: Barnaby
authors: Samantha M
authors: SM
authors: Yu
authors: Karl R
authors: KR
authors: Fath
authors: Areti
authors: A
authors: Tsiola
authors: Omid
authors: O
authors: Khalpari
authors: Ipsita A
authors: IA
authors: Banerjee
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D032701:Biomimetics / Q000379:methods*; D002460:Cell Line; D004610:Ellagic Acid / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D051381:Rats; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004610:Ellagic Acid; D012834:Silver