title: A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction.
abstract: An ultra-sensitive, fast, simple and easily operated method for sequence-specific detection of polynucleotides is proposed herein, which is based on a novel target-triggered isothermal exponential degradation reaction (TT-isoTexpDR) and the color change of probe-functionalized gold nanoparticles.
authors: Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
authors: Jing
authors: J
authors: Zhao
authors: Tao
authors: T
authors: Liu
authors: Qi
authors: Q
authors: Fan
authors: Genxi
authors: G
authors: Li
mesh_terms: D001483:Base Sequence; D015374:Biosensing Techniques / Q000295:instrumentation; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation / Q000379:methods; D003124:Colorimetry / Q000295:instrumentation; D003432:Cross-Linking Reagents / Q000737:chemistry*; D004247:DNA / Q000032:analysis / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry / Q000235:genetics; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008956:Models, Chemical; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods; D009693:Nucleic Acid Hybridization; D011119:Polynucleotides / Q000032:analysis* / Q000737:chemistry*; D013499:Surface Properties; D013696:Temperature
chemical_list: D003432:Cross-Linking Reagents; D015342:DNA Probes; D011119:Polynucleotides; D006046:Gold; D004247:DNA