title: Characterization of A phases during the cyclic alternating pattern of sleep.
abstract: OBJECTIVE
  This study aims to identify, starting from a single EEG trace, quantitative distinctive features characterizing the A phases of the Cyclic Alternating Pattern (CAP).
  
  
  METHODS
  The C3-A2 or C4-A1 EEG leads of the night recording of eight healthy adult subjects were used for this analysis. CAP was scored by an expert and the portions relative to NREM were selected. Nine descriptors were computed: band descriptors (low delta, high delta, theta, alpha, sigma and beta); Hjorth activity in the low delta and high delta bands; differential variance of the EEG signal. The information content of each descriptor in recognizing the A phases was evaluated through the computation of the ROC curves and the statistics sensitivity, specificity and accuracy.
  
  
  RESULTS
  The ROC curves show that all the descriptors have a certain significance in characterizing A phases. The average accuracy obtained by thresholding the descriptors ranges from 59.89 (sigma descriptor) to 72.44 (differential EEG variance).
  
  
  CONCLUSIONS
  The results show that it is possible to attribute a significant quantitative value to the information content of the descriptors.
  
  
  CONCLUSIONS
  This study gives a mathematical confirm to the features of CAP generally described qualitatively, and puts the bases for the creation of automatic detection methods.
authors: Politecnico di Milano, Department of Biomedical Engineering, P.zza Leonardo da Vinci 32, 20133 Milan, Italy. sara1.mariani@mail.polimi.it
authors: Sara
authors: S
authors: Mariani
authors: Elena
authors: E
authors: Manfredini
authors: Valentina
authors: V
authors: Rosso
authors: Martin O
authors: MO
authors: Mendez
authors: Anna M
authors: AM
authors: Bianchi
authors: Matteo
authors: M
authors: Matteucci
authors: Mario G
authors: MG
authors: Terzano
authors: Sergio
authors: S
authors: Cerutti
authors: Liborio
authors: L
authors: Parrino
mesh_terms: D000328:Adult; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D010507:Periodicity; D017286:Polysomnography / Q000379:methods; D012890:Sleep / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D055815:Young Adult