title: A CRTCal link between energy and life span.
abstract: Cutting down calories prolongs life, but how this works remains largely unknown. A recent study in Nature (Mair et al., 2011) shows that life span extension triggered by the energy-sensing protein kinase AMPK is mediated by an evolutionarily conserved transcriptional circuit involving CRTC-1 and CREB.
authors: Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address: anne.brunet@stanford.edu.
authors: Anne
authors: A
authors: Brunet