title: Glucose as a mitogenic hormone.
abstract: Glucose stimulates insulin secretion in β cells, which sense glucose concentrations through signals derived from glycolytic metabolism. In this issue of Cell Metabolism, Dor and colleagues (Porat et al., 2011) combine genetic, transplantation, and pharmacologic approaches to show that glucose also stimulates β cell proliferation through similar metabolic signals, providing a new framework to develop therapeutics for diabetes.
authors: Genomic Programming of Beta Cells Laboratory, Institut d'Investigacions Biomèdiques August Pi iSunyer, Barcelona 08036, Spain; Endocrinology, Hospital Clínic de Barcelona, Barcelona 08036, Spain; CIBERDEM, Barcelona 08036, Spain. Electronic address: jferrer@clinic.ub.es.
authors: Jorge
authors: J
authors: Ferrer