title: Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia.
abstract: BACKGROUND
  The mechanisms and inheritance of androgenetic alopecia (AGA) have yet to be elucidated. Several clinical studies suggest that a predisposition to AGA is affected by a variety of paternal and/or maternal hereditary factors. No previous study has addressed the association of AGA with family history based on the pattern of hair loss.
  
  
  OBJECTIVE
  The purpose of this study was to investigate paternal and/or maternal genetic influences in each type of hair loss pattern using the basic and specific (BASP) classification and to explore whether the morphology of AGA tends to be inherited in family members.
  
  
  METHODS
  Between October 2007 and September 2008, 1220 Korean participants, 998 male and 222 female, were classified according to the BASP classification at 13 university dermatologic centers. Information was collected using a standard questionnaire and BASP classification sheet.
  
  
  RESULTS
  Parental influences on anterior hairline shape in men were predominantly from the paternal side, whereas these effects were less notable in women. In the absence of a family history, statistical analysis showed a higher frequency for early-onset AGA than late-onset AGA (Pearson χ(2)P < .05). Basic types of hair loss had a higher degree of inheritance from the paternal side of the family, regardless of specific type.
  
  
  CONCLUSIONS
  The evaluation of hair loss pattern and family history was done by the patients.
  
  
  CONCLUSIONS
  Familial factors affecting the morphology of AGA differ between male and female individuals, and for each type of BASP classification.
authors: Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University, Wonju College of Medicine, Wonju, Korea. leewonsoo@yonsei.ac.kr
authors: Won-Soo
authors: WS
authors: Lee
authors: Yoonseok
authors: Y
authors: Oh
authors: Jae Hong
authors: JH
authors: Ji
authors: Jang Kyu
authors: JK
authors: Park
authors: Do Won
authors: DW
authors: Kim
authors: Woo-Young
authors: WY
authors: Sim
authors: Hyung Ok
authors: HO
authors: Kim
authors: Seon-Wook
authors: SW
authors: Hwang
authors: Tae Young
authors: TY
authors: Yoon
authors: Young Chul
authors: YC
authors: Kye
authors: Gwang Seong
authors: GS
authors: Choi
authors: Moon-Bum
authors: MB
authors: Kim
authors: Chang-Hoon
authors: CH
authors: Huh
authors: Byung In
authors: BI
authors: Ro
authors: Seong-Jin
authors: SJ
authors: Kim
authors: Jae-Hong
authors: JH
authors: Kim
authors: Yoonhee
authors: Y
authors: Lee
mesh_terms: D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000505:Alopecia / Q000145:classification / Q000453:epidemiology* / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D015331:Cohort Studies; D005260:Female; D020022:Genetic Predisposition to Disease / Q000453:epidemiology*; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D015995:Prevalence; D017678:Sex Distribution; D055815:Young Adult