title: Comparison of two early loading protocols in full arch reconstructions in the edentulous maxilla using the Cresco prosthetic system: a three-arm parallel group randomized-controlled trial.
abstract: OBJECTIVE
  Appraise the feasibility of interchanging conventional components of a fixed dental prosthesis (FDP) with those of Cresco in two different early loading protocols.
  
  
  METHODS
  In five centers patients with an edentulous, fully healed maxilla were recruited to partake in a three-arm blinded randomized-controlled trial (RCT). Each patient received 5/6 implants using a single-stage surgery approach to support a 10/12-unit FDP. The implants used were SLA solid screw two-part implants. In test groups 1 and 2 components from Cresco were used and the implants loaded 10 days or 6-8 weeks post-implant placement. Group 3 received their FDP fabricated with conventional components 6-8 weeks post-implant placement. Patients were followed up 3 years.
  
  
  RESULTS
  Of 36 patients, 30 remained after 3 years. The adjusted means and ranges of changes in crestal bone levels were -0.65, -0.5 and -0.4 mm in groups 1, 2 and 3, respectively. The change from baseline was statistically significant in all treatment groups. Adjusting for the difference in implant depth, there was an expected additional change in bone level of -0.29 mm by each 1 mm the implant was placed deeper. There was no significant difference between the 6-8 weeks post-implant placement loading Cresco group vs. the control group or between the two Cresco groups.
  
  
  CONCLUSIONS
  The vertical placement has more effect on bone loss than the fabrication technique used for the suprastructure and whether the implants were loaded after 10 days vs. 6-8 weeks.
authors: Faculty of Dentistry, University of Toronto, ON, Canada. a.jokstad@dentistry.utoronto.ca
authors: Asbjorn
authors: A
authors: Jokstad
authors: Stefan
authors: S
authors: Ellner
authors: Anne
authors: A
authors: Gussgard
mesh_terms: D000368:Aged; D016301:Alveolar Bone Loss / Q000209:etiology / Q000473:pathology; D000539:Alveolar Process / Q000473:pathology; D015519:Bone Density / Q000502:physiology; D000044:Dental Abutments; D015921:Dental Implants; D003774:Dental Plaque Index; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D003779:Denture Design; D004955:Esthetics, Dental; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057893:Immediate Dental Implant Loading / Q000379:methods*; D007575:Jaw, Edentulous / Q000534:rehabilitation* / Q000601:surgery; D008297:Male; D008409:Mastication / Q000502:physiology; D008437:Maxilla / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D017060:Patient Satisfaction; D057873:Peri-Implantitis / Q000209:etiology; D010512:Periodontal Index; D016300:Radiography, Bitewing; D016037:Single-Blind Method; D013649:Taste / Q000502:physiology
chemical_list: D015921:Dental Implants