title: [Efficacy of new antiepileptic drugs and the next generation drugs].
abstract: Recent development and success in the field of new antiepileptic drug treatment, has resulted in the commercialization of many new drugs. The efficacy of these drugs has been assessed in many countries. Despite the progress in USA and European countries, a time lag of approximately 10 years concerning these new drugs exists in Japan. Since 2000, the above mentioned new drugs have been commercially available and are used to treat many patients with refractory epileptic seizures and verify their efficacy as well in Japan. Induced pluripotent stem (iPS) cells, which were invented in Japan are expected to accelerate the invention of more effective antiepileptic drugs in the near future.
authors: Morikawa Clinic, Nichimaru Nagoya Buil, Shin-Sakae-cho, Naka-Ku, Nagoya-city, Aichi, Japan.
authors: Tateki
authors: T
authors: Morikawa
mesh_terms: D000588:Amines; D000927:Anticonvulsants; D002220:Carbamazepine / Q000031:analogs & derivatives; D003509:Cyclohexanecarboxylic Acids; D017277:Drug Approval; D015195:Drug Design; D016903:Drug Monitoring; D005632:Fructose / Q000031:analogs & derivatives; D000077206:Gabapentin; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D000077213:Lamotrigine; D000077287:Levetiracetam; D010889:Piracetam / Q000031:analogs & derivatives; D000077236:Topiramate; D014227:Triazines; D005680:gamma-Aminobutyric Acid
chemical_list: D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D014227:Triazines; C476610:oxcarbamazepine; D000077236:Topiramate; D005632:Fructose; D002220:Carbamazepine; D000077287:Levetiracetam; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin; D000077213:Lamotrigine; D010889:Piracetam