title: Sensitive (13)C- (13)C correlation spectra of amyloid fibrils at very high spinning frequencies and magnetic fields.
abstract: Sensitive 2D solid-state (13)C-(13)C correlation spectra of amyloid β fibrils have been recorded at very fast spinning frequencies and very high magnetic fields. It is demonstrated that PARIS-xy recoupling using moderate rf amplitudes can provide structural information by promoting efficient magnetization transfer even under such challenging experimental conditions. Furthermore, it has been shown both experimentally and by numerical simulations that the method is not very sensitive to dipolar truncation effects and can reveal direct transfer across distances of about 3.5-4 Å.
authors: Département de Chimie, Ecole Normale Supérieure, Paris, France.
authors: Markus
authors: M
authors: Weingarth
authors: Yuichi
authors: Y
authors: Masuda
authors: K
authors: K
authors: Takegoshi
authors: Geoffrey
authors: G
authors: Bodenhausen
authors: Piotr
authors: P
authors: Tekely
mesh_terms: D000682:Amyloid / Q000737:chemistry*; D016229:Amyloid beta-Peptides / Q000138:chemical synthesis / Q000737:chemistry; D002247:Carbon Isotopes / Q000737:chemistry*; D003198:Computer Simulation; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000682:Amyloid; D016229:Amyloid beta-Peptides; D002247:Carbon Isotopes