title: Inhalation anesthesia equipment for rats with provision of simultaneous anesthetic and oxygen.
abstract: OBJECTIVE
  To introduce a model of equipment for inhalation anesthesia in rats that offers better control of both flow and losses of ether during induction, maintenance, and recuperation.
  
  
  METHODS
  The equipment consists of an air compressor with two outlets, a closed glass induction chamber, a glass reservoir for the anesthetic agent, a pediatric inhalation mask, a three-way stopcock, a Y-connector, and urinary catheters. Three hundred Wistar rats (Rattus norvegicus albinus) were given inhalation anesthesia. The evaluated parameters were equipment operation, duration of each phase of anesthesia, corneal reflex, muscular tonus, respiration during induction and maintenance, and volume of anesthesia.
  
  
  RESULTS
  The average time taken for induction was 7.3 minutes; the average anesthetic recuperation time was 6.4 minutes. The amount of anesthetic used varied according to the weight of the animal, with the average volume of ether used being 6.5ml/hour. The availability of oxygen (room air) decreased the recuperation time and averted both respiratory depression and insufficient depth of anesthesia.
  
  
  CONCLUSIONS
  The proposed equipment is practical, inexpensive, and allows for satisfactory control of anesthetic parameters during the entire procedure, making inhalation anesthesia in rats safe and essentially complication free.
authors: Head Division of Pediatric Surgery and Experimental Surgery, FACIME, UESPI, Piaui, Brazil. edinaldomiranda@hotmail.com
authors: Edinaldo Gonçalves de
authors: EG
authors: Miranda
authors: Vinícius Pontes do
authors: VP
authors: Nascimento
authors: Daniel Reis
authors: DR
authors: Waisberg
authors: Manoel Wilkley Gomes de
authors: MW
authors: Sousa
authors: Marcel Fernando Miranda Batista
authors: MF
authors: Lima
authors: Danilo dos Santos
authors: Ddos S
authors: Silva
authors: Jaques
authors: J
authors: Waisberg
mesh_terms: D000769:Anesthesia, Inhalation / Q000295:instrumentation* / Q000379:methods; D000776:Anesthesiology / Q000295:instrumentation* / Q000379:methods; D000777:Anesthetics / Q000008:administration & dosage; D000818:Animals; D005260:Female; D008297:Male; D010100:Oxygen / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000777:Anesthetics; D010100:Oxygen