title: [Sexual dysfunction in women with overactive bladder and their correction with m-cholinolytic spasmex].
abstract: A 4-month course of spasmex (15 mg three times a day) was conducted in 57 females (age 18-69 years, mean age 48 years) suffering from imperative urination manifesting as pollakiuria, imperative urges and urgent urinary incontinence in combination with sexual disorders. After the treatment the score of urination disorders went down from 21.4 to 12.7. Quality of life score decreased from 4.3 to 1.7. Sexual dysfunction diminished from 3.6 to 0.8 points. Clinical data showed that spasmex has a marked effect on m-cholinoreceptors, is well tolerated, has a moderate spasmolytic effect on the smooth muscles of the lower urinary tract. Moreover, spasmex can be used for correction of female sexual dysfunction caused by overactive bladder.
authors: T I
authors: TI
authors: Danilova
authors: V V
authors: VV
authors: Danilov
authors: S A
authors: SA
authors: Luchinskiĭ
authors: V V
authors: VV
authors: Danilov
authors: A V
authors: AV
authors: Vasil'chenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001561:Benzilates; D005260:Female; D006801:Humans; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D009662:Nortropanes / Q000008:administration & dosage / Q000627:therapeutic use*; D011788:Quality of Life; D012735:Sexual Dysfunction, Physiological / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D055815:Young Adult
chemical_list: D001561:Benzilates; D018727:Muscarinic Antagonists; D009662:Nortropanes; C003330:trospium chloride