title: Fusarium falciforme vertebral abscess and osteomyelitis: case report and molecular classification.
abstract: Fusarium is a ubiquitous mold that can cause superficial infections such as keratitis and onychomycosis in immunocompetent humans; however, infections in immunocompromised hosts can be fatal. We report an unusual case of epidural abscess and vertebral osteomyelitis in a patient with an autoimmune disorder who was on long-term glucocorticoids. Multilocus DNA sequence-based typing revealed that the infection was caused by a novel three-locus haplotype of Fusarium falciforme designated FSSC 3+4qqq.
authors: Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30030, USA. sedupug@emory.edu
authors: Srilatha
authors: S
authors: Edupuganti
authors: Nadine
authors: N
authors: Rouphael
authors: Aneesh
authors: A
authors: Mehta
authors: Molly
authors: M
authors: Eaton
authors: John G
authors: JG
authors: Heller
authors: Adam
authors: A
authors: Bressler
authors: Mary
authors: M
authors: Brandt
authors: Kerry
authors: K
authors: O'Donnell
mesh_terms: D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D020802:Epidural Abscess / Q000150:complications / Q000382:microbiology* / Q000473:pathology*; D005260:Female; D005670:Fusarium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D058885:Multilocus Sequence Typing; D016533:Mycological Typing Techniques; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D010019:Osteomyelitis / Q000150:complications / Q000382:microbiology / Q000473:pathology; D017422:Sequence Analysis, DNA; D013166:Spondylitis / Q000150:complications / Q000382:microbiology* / Q000473:pathology*
chemical_list: D004271:DNA, Fungal; D005938:Glucocorticoids