title: Protecting group and switchable pore-discriminating adsorption properties of a hydrophilic-hydrophobic metal-organic framework.
abstract: Formed by linking metals or metal clusters through organic linkers, metal-organic frameworks are a class of solids with structural and chemical properties that mark them out as candidates for many emerging gas storage, separation, catalysis and biomedical applications. Important features of these materials include their high porosity and their flexibility in response to chemical or physical stimuli. Here, a copper-based metal-organic framework has been prepared in which the starting linker (benzene-1,3,5-tricarboxylic acid) undergoes selective monoesterification during synthesis to produce a solid with two different channel systems, lined by hydrophilic and hydrophobic surfaces, respectively. The material reacts differently to gases or vapours of dissimilar chemistry, some stimulating subtle framework flexibility or showing kinetic adsorption effects. Adsorption can be switched between the two channels by judicious choice of the conditions. The monoesterified linker is recoverable in quantitative yield, demonstrating possible uses of metal-organic frameworks in molecular synthetic chemistry as 'protecting groups' to accomplish selective transformations that are difficult using standard chemistry techniques.
authors: EaStCHEM School of Chemistry, University of St Andrews, St Andrews KY169ST, UK.
authors: M Infas H
authors: MI
authors: Mohideen
authors: Bo
authors: B
authors: Xiao
authors: Paul S
authors: PS
authors: Wheatley
authors: Alistair C
authors: AC
authors: McKinlay
authors: Yang
authors: Y
authors: Li
authors: Alexandra M Z
authors: AM
authors: Slawin
authors: David W
authors: DW
authors: Aldous
authors: Naomi F
authors: NF
authors: Cessford
authors: Tina
authors: T
authors: Düren
authors: Xuebo
authors: X
authors: Zhao
authors: Rachel
authors: R
authors: Gill
authors: K Mark
authors: KM
authors: Thomas
authors: John M
authors: JM
authors: Griffin
authors: Sharon E
authors: SE
authors: Ashbrook
authors: Russell E
authors: RE
authors: Morris
mesh_terms: D000327:Adsorption; D003300:Copper / Q000737:chemistry; D004951:Esterification; D005740:Gases / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D009566:Nitrates / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013696:Temperature; D013816:Thermodynamics; D013818:Thermogravimetry; D014233:Tricarboxylic Acids / Q000737:chemistry; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D005740:Gases; D009566:Nitrates; D009942:Organometallic Compounds; D014233:Tricarboxylic Acids; D014867:Water; D003300:Copper; C516433:copper(II) nitrate; C069849:trimesic acid; D000432:Methanol