title: Lipid levels in Biomphalaria glabrata infected with different doses of Echinostoma paraensei miracidia.
abstract: The effect of experimental exposure of Biomphalaria glabrata to different doses (5 and 50) of Echinostoma paraensei miracidia on the total levels of cholesterol and triglycerides circulating in the hemolymph and the neutral lipids in the digestive gland-gonad (DGG) complex were studied. The snails were dissected one, two, three and four weeks after infection to collect the hemolymph and DGG tissue, to measure the levels of cholesterol and triglycerides in the hemolymph and neutral lipids in the tissue. The results for the hemolymph showed a similar order of variation for both substrates tested in the first week after infection. The reduced levels of these lipids in the infected snails indicate intense use of these substrates both by the intermediate host and the parasite, suggesting its probable participation in the energy metabolism and structural construction of the developing larval stages. Alterations in the profile of neutral lipids in the DGG were also found. The results obtained indicate that in this model, the lipid metabolism depends on the miracidial dose used.
authors: Curso de Pós-Graduação em Ciências Veterinárias, Departamento de Parasitologia Animal, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Km7, BR 465, Antiga estrada Rio-São Paulo, 23890-000 Seropédica, RJ, Brazil.
authors: Vinícius Menezes
authors: VM
authors: Tunholi-Alves
authors: Victor Menezes
authors: VM
authors: Tunholi
authors: Patrícia
authors: P
authors: Gôlo
authors: Danilo
authors: D
authors: Lustrino
authors: Arnaldo
authors: A
authors: Maldonado
authors: Vânia Rita Elias Pinheiro
authors: VR
authors: Bittencourt
authors: Maria de Lurdes de Azevedo
authors: Mde L
authors: Rodrigues
authors: Jairo
authors: J
authors: Pinheiro
mesh_terms: D000818:Animals; D001700:Biomphalaria / Q000737:chemistry / Q000469:parasitology*; D002784:Cholesterol / Q000032:analysis*; D002788:Cholesterol Esters / Q000032:analysis; D006224:Cricetinae; D004449:Echinostoma / Q000502:physiology*; D005227:Fatty Acids / Q000032:analysis; D006458:Hemolymph / Q000737:chemistry; D006790:Host-Parasite Interactions; D008647:Mesocricetus; D014280:Triglycerides / Q000032:analysis*
chemical_list: D002788:Cholesterol Esters; D005227:Fatty Acids; D014280:Triglycerides; D002784:Cholesterol