title: Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms.
authors: O
authors: O
authors: Abdel-Wahab
authors: A
authors: A
authors: Pardanani
authors: J
authors: J
authors: Patel
authors: M
authors: M
authors: Wadleigh
authors: T
authors: T
authors: Lasho
authors: A
authors: A
authors: Heguy
authors: M
authors: M
authors: Beran
authors: D G
authors: DG
authors: Gilliland
authors: R L
authors: RL
authors: Levine
authors: A
authors: A
authors: Tefferi
mesh_terms: D000368:Aged; D019943:Amino Acid Substitution; D001752:Blast Crisis / Q000235:genetics* / Q000401:mortality; D015331:Cohort Studies; D004273:DNA, Neoplasm / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D049308:Dioxygenases; D000071221:Enhancer of Zeste Homolog 2 Protein; D005091:Exons / Q000235:genetics; D005260:Female; D005838:Genotype; D018095:Germ-Line Mutation; D006801:Humans; D015477:Leukemia, Myelomonocytic, Chronic / Q000235:genetics* / Q000401:mortality; D008297:Male; D020125:Mutation, Missense; D009196:Myeloproliferative Disorders / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D009363:Neoplasm Proteins / Q000235:genetics*; D063151:Polycomb Repressive Complex 2; D020641:Polymorphism, Single Nucleotide; D055728:Primary Myelofibrosis / Q000235:genetics* / Q000401:mortality; D011379:Prognosis; D011518:Proto-Oncogene Proteins / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics; D017422:Sequence Analysis, DNA; D014157:Transcription Factors / Q000235:genetics*
chemical_list: C473949:ASXL1 protein, human; D004273:DNA, Neoplasm; D004268:DNA-Binding Proteins; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; D049308:Dioxygenases; C541081:TET2 protein, human; C498409:EZH2 protein, human; D000071221:Enhancer of Zeste Homolog 2 Protein; D063151:Polycomb Repressive Complex 2