title: Nongenetic factors associated with human handedness and footedness in Japanese twin children.
abstract: OBJECTIVE
  The aim of this study is to clarify the factors related to the handedness and footedness of twins using two of the largest databases on Japanese twins available.
  
  
  METHODS
  The first group consisted of 1,131 twin pairs, all school children either 11 or 12 years old (S group), and the second group consisted of 951 twin pairs of different ages (1-15 years) in several maternal associations (M group). All data were gathered using a questionnaire. Factors associated with the handedness or footedness of twin individuals were analyzed by univariate and multivariate logistic analyses.
  
  
  RESULTS
  Multivariate logistic analysis showed that for handedness, birth year (OR=1.02) and neonatal asphyxia (OR=1.62) were selected in the S group, and sex (OR=1.34), the age of twins (OR=1.56), parity (OR=1.31), gestational age (OR=1.58), and family history (OR=1.82) were selected in the M group. for footedness, birth complications (OR=1.37) were selected in the S group, and sex (OR=1.33), the age of twins (OR=1.69), gestational age (OR=1.83), and family history (OR=2.49) were selected in the M group. Factors associated with handedness and footedness specific to twins, such as zygosity, placentation, birth order within twin pairs and the sex of the cotwin, were not found, although being a twin might have some effects.
  
  
  CONCLUSIONS
  It was concluded that factors that affect handedness or footedness in general, such as sex, birth year, age, parity, neonatal asphyxia, gestational age, birth complications, and family history, seem to have stronger effects on handedness and footedness than being a twin.
authors: Department of Health Science, Ishikawa Prefectural Nursing University, Tsu 7-1 Nakanuma, 929-1212, Kahoku, Ishikawa, Japan, sooki@ishikawa-nu.ac.jp.
authors: Syuichi
authors: S
authors: Ooki