title: Occurrence of co-planar polybrominated/chlorinated biphenyls (PXBs), polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in breast milk of women from Spain.
abstract: In this study, for the first time, levels and accumulation profiles of eight currently available polybrominated/chlorinated biphenyl congeners (PXBs; XB-77, -105, -118, -126A, -126B, -126C, -156 and -169, named according to IUPAC nomenclature) in human breast milk collected form Spanish women in 2005 were reported. Concentrations and congener specific profiles of polychlorinated biphenyls (PCBs), including co-planar PCBs, (co-PCBs) and polybrominated diphenyl ethers (PBDEs) were also reported. A concentration of 0.45 pg g(-1) lipid weight was found for total PXBs, and arithmetic mean concentrations of 125, 25 and 5.5 ng g(-1) lipid weight were determined for total PCBs, co-PCBs and total PBDEs respectively. Detectable levels of all congeners investigated, except CB-123 and XB-169 were found. Levels of PCBs were similar to those found in Spanish samples collected after 2000, and lower than those obtained before 2000. CB-138, -153 and -180 were the predominant PCB congeners. PBDE levels, dominated by BDE-47, -99, -100 and -209, were lower than PCB levels. PXB concentrations were the lowest, with XB-156 being the most abundant. The concentration levels of PCBs and PBDEs found in this study were in the same range as those from other European countries. Levels of PXBs were much lower than published values determined in Japan which were the only data found in the literature.
authors: Department of Instrumental Analysis and Environmental Chemistry, IQOG-CSIC., Juan de la Cierva 3, 28006 Madrid, Spain.
authors: B
authors: B
authors: Gómara
authors: L
authors: L
authors: Herrero
authors: G
authors: G
authors: Pacepavicius
authors: S
authors: S
authors: Ohta
authors: M
authors: M
authors: Alaee
authors: M J
authors: MJ
authors: González
mesh_terms: D000293:Adolescent; D000328:Adult; D004785:Environmental Pollutants / Q000378:metabolism*; D004787:Environmental Pollution / Q000706:statistics & numerical data; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000378:metabolism*; D006801:Humans; D018811:Maternal Exposure / Q000706:statistics & numerical data*; D008895:Milk, Human / Q000378:metabolism*; D011075:Polybrominated Biphenyls / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D013030:Spain; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; D011078:Polychlorinated Biphenyls