title: Catheter-directed thrombolysis with tPA to restore renal function after iliac venous thrombosis post-renal transplantation.
abstract: BACKGROUND
  Successful salvage of a failing renal allograft secondary to compromised venous outflow from acute deep venous thrombus (DVT) has not been reported in the post-operative setting.
  
  
  METHODS
  We present a case of acute DVT extending from the popliteal vein to the bifurcation of the inferior vena cava leading to renal allograft dysfunction in the post-operative period. The allograft was successfully salvaged with catheter directed thrombolysis of the DVT with tPA through the ipsilateral popliteal vein over a 48 hr period.
  
  
  CONCLUSIONS
  Post-operative renal transplant dysfunction secondary to iliac vein thrombosis can be successfully treated with catheter-directed thrombolysis using tPA.
authors: Department of Surgery, Schulich School of Medicine, Multiorgan Transplant Program, London Health Sciences Centre, London, ON, Canada.
authors: Courtney
authors: C
authors: Fulton
authors: Tom
authors: T
authors: McGregor
authors: Tom L
authors: TL
authors: Forbes
authors: David
authors: D
authors: Peck
authors: Patrick P W
authors: PP
authors: Luke
mesh_terms: D000368:Aged; D002404:Catheterization; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D007084:Iliac Vein; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000502:physiology; D008297:Male; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000209:etiology*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator