title: Inter-individual variability of oscillatory responses to subject's own name. A single-subject analysis.
abstract: In previous studies event-related potentials and oscillations in response to subject's own name have been analyzed extensively on group-level in healthy subjects and in patients with a disorder of consciousness. Subject's own name as a deviant produces a P3. With equiprobable stimuli, non-phase-locked alpha oscillations are smaller in response to subject's own name compared to other names or subject's own name backwards. However, little is known about replicability on a single-subject level. Seventeen healthy subjects were assessed in an own-name paradigm with equiprobable stimuli of subject's own name, another name, and subject's own name backwards. Event-related potentials and non-phase locked oscillations were analyzed with single-subject, non-parametric statistics. No consistent results were found either for ERPs or for the non-phase locked changes of oscillatory activities. Only 4 subjects showed a robust effect as expected, that is, a lower activity in the alpha-beta range to subject's own name compared to other conditions. Four subjects elicited a higher activity for subject's own name. Thus, analyzing the EEG reactivity in the own-name paradigm with equiprobable stimuli on a single-subject level yields a high variance between subjects. In future research, single-subject statistics should be applied for examining the validity of physiologic measurements in other paradigms and for examining the pattern of reactivity in patients.
authors: Neuroscience Institute & Center for Neurocognitive Research, Christian-Doppler-Clinic, Paracelsus Private Medical University, Salzburg, Austria. yvonne.hoeller@sbg.ac.at
authors: Yvonne
authors: Y
authors: Höller
authors: Martin
authors: M
authors: Kronbichler
authors: Jürgen
authors: J
authors: Bergmann
authors: Julia Sophia
authors: JS
authors: Crone
authors: Elisabeth Verena
authors: EV
authors: Schmid
authors: Stefan
authors: S
authors: Golaszewski
authors: Gunther
authors: G
authors: Ladurner
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D003243:Consciousness / Q000502:physiology*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010507:Periodicity; D011571:Psychoacoustics; D012649:Self Concept; D018709:Statistics, Nonparametric; D055815:Young Adult