title: [Hereditary periodical fever syndromes].
abstract: Autoinflammatory diseases are characterized by attacks of apparently unprovoked inflammation without significant levels of autoantibodies or antigen-specific T-cells. Within the past decade, a number of different genetic causes of fever syndromes have been identified: familial Mediterranean fever (FMF), hyper IgD syndrome, cryopyrin-associated periodic syndromes and tumour necrosis factor receptor-associated periodic syndrome. The recent awareness and recognition of pathogenic mechanism of these diseases have led to new possibilities for medical treatment with targeted biological agents.
authors: Børneafdelingen, Århus Universitetshospital, Skejby, 8200 Århus N, Denmark. t.herlin@dadlnet.dk
authors: Troels
authors: T
authors: Herlin
authors: Nini
authors: N
authors: Sørensen
authors: Jens
authors: J
authors: Veirum
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D056587:Cryopyrin-Associated Periodic Syndromes / Q000188:drug therapy / Q000235:genetics / Q000276:immunology; D010505:Familial Mediterranean Fever / Q000188:drug therapy / Q000235:genetics / Q000276:immunology; D005334:Fever; D056660:Hereditary Autoinflammatory Diseases / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D054078:Mevalonate Kinase Deficiency / Q000188:drug therapy / Q000235:genetics / Q000276:immunology; D050257:Tubulin Modulators / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D007155:Immunologic Factors; D050257:Tubulin Modulators; D003078:Colchicine