title: Relationship between dysphagia and depressive states in patients with Parkinson's disease.
abstract: Aspiration pneumonia related to dysphagia is known to be the leading cause of death in patients with Parkinson's disease (PD). We investigated the relationship between depressive states and dysphagia in patients with PD. A hundred and twenty-seven PD patients gave their informed consent and were enrolled in this study. We used the Beck Depression Inventory (BDI) questionnaire to determine the participants' depressive states, and also used a questionnaire to assess participants' state of dysphagia. Participants were divided into four groups according to their BDI score. We compared the PD patients with Swallowing Disturbances Questionnaire (SDQ) scores of more than or equal to 11 with the SDQ scores of less than 11 regarding depressive categories. A logistic regression analysis was conducted to calculate odds ratios (ORs) and their 95% confidence intervals (95%CI) adjusting for age, sex, disease duration, wearing-off phenomenon and severity of movement disorder. OR (95%CI) of depressive categories, in which the trivial class was set as a reference group, were 3.28 (0.93-11.55), 13.44 (3.10-58.16), 30.35 (5.65-162.97) in the mild class, the moderate class and the severe class, respectively. This study suggests that there may be a strong relationship between depressive states and dysphagia in patients with PD.
authors: Department of Public Health, Sapporo Medical University School of Medicine, Hokkaido, Japan. han@yamaguchi-u.ac.jp
authors: Meng
authors: M
authors: Han
authors: Hirofumi
authors: H
authors: Ohnishi
authors: Michio
authors: M
authors: Nonaka
authors: Rika
authors: R
authors: Yamauchi
authors: Takayoshi
authors: T
authors: Hozuki
authors: Takashi
authors: T
authors: Hayashi
authors: Masaki
authors: M
authors: Saitoh
authors: Shin
authors: S
authors: Hisahara
authors: Tomihiro
authors: T
authors: Imai
authors: Shun
authors: S
authors: Shimohama
authors: Mitsuru
authors: M
authors: Mori
mesh_terms: D000368:Aged; D003680:Deglutition Disorders / Q000150:complications* / Q000453:epidemiology; D003863:Depression / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D016017:Odds Ratio; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*; D011015:Pneumonia, Aspiration / Q000150:complications / Q000523:psychology; D011795:Surveys and Questionnaires