title: [Clinical features and hospital complications of patients with acute coronary syndromes according to smoking habits].
abstract: OBJECTIVE
  Current smoking patients with acute coronary syndromes (ACS) seem to have better prognosis during hospital stay. The objective of this study was to describe the clinical characteristics and complications of patients with ACS according to smoking habits.
  
  
  METHODS
  Observational, multicentre and nationwide registry. Primary endpoint was hospital mortality and secondary endpoint was the combination of mortality, angina or heart failure.
  
  
  RESULTS
  825 ACS patients were collected. Current smokers were 413 (50.1%) and their mean age was 12 years lower than the rest and also had lower prevalence of risk factors or previous cardiovascular disease. Complications and mortality were similar according to smoking habits. Multivariate adjusted analysis identified age > 75 (OR: 12.80, 95% CI 1.35-41.44; p=0.03) and GFR < 60 ml/min/1.73 m(2) (OR: 10.20, 95% CI 1.06-97.92; p=0.04) independently associated with mortality; age > 75 (OR: 1.72, 95% CI 1.03-2.84; p=0.04), GFR < 60 ml/min/1.73 m(2) (OR: 1.76, 95% CI 1.08-2.91; p=0.023) and current smoking (OR: 1.05, 95% CI 1.01-1.10; p=0.02) were independently associated with the combined end-point. Elderly current smokers patients had the highest mortality rate (19.0%) followed by elderly former smokers patients (5.8%).
  
  
  CONCLUSIONS
  Current smoker patients with ACS have lower mean age and have similar hospital complications.
authors: Hospital Universitario de San Juan, Alicante, España. acorderofort@gmail.com
authors: Alberto
authors: A
authors: Cordero
authors: Vicente
authors: V
authors: Bertomeu-Martínez
authors: Pilar
authors: P
authors: Mazón
authors: Enrique
authors: E
authors: Galve
authors: Iñaki
authors: I
authors: Lekuona
authors: Fernando
authors: F
authors: de la Guía
authors: Juan
authors: J
authors: Cosín
authors: José
authors: J
authors: García Gómez
authors: Francisco
authors: F
authors: Roncales
authors: José Ramón
authors: JR
authors: González-Juanatey
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D050171:Dyslipidemias / Q000453:epidemiology; D005260:Female; D005919:Glomerular Filtration Rate; D006333:Heart Failure / Q000453:epidemiology / Q000209:etiology; D017052:Hospital Mortality; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology