title: A palladium-catalyzed three-component cross-coupling of conjugated dienes or terminal alkenes with vinyl triflates and boronic acids.
abstract: A three-component coupling of vinyl triflates and boronic acids to alkenes catalyzed by palladium is reported. Using 1,3-dienes, selective 1,2-alkene difunction-alization is observed, whereas the use of terminal alkenes results in 1,1-alkene difunctionalization. The reaction outcome is attributed to the formation of stabilized, cationic Pd-π-allyl intermediates to regulate β-hydride elimination.
authors: Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-085, United States.
authors: Longyan
authors: L
authors: Liao
authors: Ranjan
authors: R
authors: Jana
authors: Kaveri Balan
authors: KB
authors: Urkalan
authors: Matthew S
authors: MS
authors: Sigman
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D008698:Mesylates / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D001897:Boronic Acids; D008698:Mesylates; D014753:Vinyl Compounds; C437735:vinyl triflate; D010165:Palladium