title: Serum interleukin-18 binding protein increases with behavior different from IL-18 in patients with diabetic nephropathy.
abstract: We investigated alterations between serum interleukin 18 (IL-18) and IL-18 binding protein (18BP) in T2DM patients. 18 BP began to increase after IL-18 increased and reached a threshold, in which case kidney dysfunction would have developed. These data indicate that 18BP might express glomerular dysfunction more closely than IL-18.
authors: Department of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, 30-1 Oyaguchi-kamimachi, Itabashiku, Tokyo 173-8610, Japan. tfujita@med.nihon-u.ac.jp
authors: Takayuki
authors: T
authors: Fujita
authors: Chie
authors: C
authors: Shimizu
authors: Yoshinobu
authors: Y
authors: Fuke
authors: Atsushi
authors: A
authors: Satomura
authors: Masanori
authors: M
authors: Abe
authors: Kazo
authors: K
authors: Kaizu
authors: Koichi
authors: K
authors: Matsumoto
authors: Masayoshi
authors: M
authors: Soma
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D003928:Diabetic Nephropathies / Q000097:blood* / Q000503:physiopathology; D005260:Female; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D020382:Interleukin-18 / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D020382:Interleukin-18; C118370:interleukin-18 binding protein