title: Novel N-chloroheterocyclic antimicrobials.
abstract: Antimicrobial compounds with broad-spectrum activity and minimal potential for antibiotic resistance are urgently needed. Toward this end, we prepared and investigated a novel series of N-chloroheterocycles. Of the compounds examined, the N-chloroamine series were found superior over N-chloroamide series in regards to exhibiting high antimicrobial activity, low cytotoxicity, and long-term aqueous stability.
authors: NovaBay Pharmaceuticals Inc., 5980 Horton St. Suite 550, Emeryville, CA 94608, USA.
authors: Charles
authors: C
authors: Francavilla
authors: Eric D
authors: ED
authors: Turtle
authors: Bum
authors: B
authors: Kim
authors: Donogh J R
authors: DJ
authors: O'Mahony
authors: Timothy P
authors: TP
authors: Shiau
authors: Eddy
authors: E
authors: Low
authors: Nichole J
authors: NJ
authors: Alvarez
authors: Chris E
authors: CE
authors: Celeri
authors: Louisa
authors: L
authors: D'Lima
authors: Lisa C
authors: LC
authors: Friedman
authors: Francis S
authors: FS
authors: Ruado
authors: Ping
authors: P
authors: Xu
authors: Meghan E
authors: ME
authors: Zuck
authors: Mark B
authors: MB
authors: Anderson
authors: Ramin Ron
authors: RR
authors: Najafi
authors: Rakesh K
authors: RK
authors: Jain
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002713:Chlorine / Q000737:chemistry; D005658:Fungi / Q000187:drug effects*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure
chemical_list: D000890:Anti-Infective Agents; D006571:Heterocyclic Compounds; D002713:Chlorine