title: Total resection of lesser curvature for radical treatment of distal gastric carcinoma.
abstract: OBJECTIVE
  The extent of gastric resection and lymphadenectomy for curative treatment of distal gastric cancer remains controversial. The present study investigated the efficacy of total resection of the lesser curvature as radical surgery for distal gastric carcinoma.
  
  
  METHODS
  Patients with pathologically confirmed advanced distal gastric cancer seen at our hospital from 2003 to 2006 were randomly selected to receive either total resection of lesser curvature (Group A, N=60) or traditional subtotal gastrectomy (Group B, N=60), both with D2 lymph node dissection. Patient and tumor characteristics, lymph node metastases, and surgical outcomes were analyzed.
  
  
  RESULTS
  Three-year survival rates were 56.7% and 28.3% for Groups A and B, respectively (p = 0.042). A total of 467 (30.5%) and 225 (24.7%) tumor-positive lymph nodes were resected in Groups A and B, respectively (p = 0.002). Tumor recurrence rate was 1.6% (1/60) in Group A and 11.6% (7/60) in Group B (p = 0.061).
  
  
  CONCLUSIONS
  Total resection of the lesser curvature with D2 level lymph node dissection prolonged patient survival and decreased tumor recurrence. This surgical approach should be considered for the treatment of patients with distal gastric carcinoma.
authors: Department of General Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China.
authors: Zeng-Hai
authors: ZH
authors: Lin
authors: Tao
authors: T
authors: Ma
authors: Ke
authors: K
authors: Yang
authors: Zhao-Ming
authors: ZM
authors: Li
authors: Wei-Cheng
authors: WC
authors: Liu
authors: Zai-De
authors: ZD
authors: Wu
authors: Jian-Ping
authors: JP
authors: Gong
authors: Qun
authors: Q
authors: Yan
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D016009:Chi-Square Distribution; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome