title: [Evolution of prenatal diagnosis of congenital heart diseases in Indre-et-Loire (France) over a period of 15 years].
abstract: The value of prenatal diagnosis of major congenital heart diseases (CHDs) has already been proved. In this study, we observed the evolution of the detection rate of CHDs and the quality of the diagnoses over a 15-year period in the Indre-et-Loire department of France.
  
  
  METHODS
  Retrospective analysis of the quantitative and qualitative data of prenatal diagnosis between 2000 and 2005 (period 3) and comparison with studies conducted from 1991 to 1994 (period 1) and from 1995 to 1999 (period 2). The CHDs considered to be detectable are the major CHDs with neonatal symptoms. In order to analyze the quality of prenatal diagnosis, each diagnosis was classified as correct, false, or incomplete during period 3.
  
  
  RESULTS
  Period 3: 65.7% detectable CHDs were screened. Using period 1 criteria for prenatal diagnosis, the percentage of CHDs detected for periods 1, 2, and 3 was 43.2, 66.7, and 78%, respectively. Between periods 2 and 3, the detection rate increased from 52 to 74% for CHDs diagnosed with the visualization of the outflow tract. It increased from 63 to 71% for CHDs diagnosed with a four-chamber view. During period 3, diagnoses made by a pediatric cardiologist were correct and complete in 80% of cases. It was less than 25% otherwise.
  
  
  CONCLUSIONS
  The improvement of prenatal diagnosis over time results from technological progress, the greater experience of ultrasonographers, and the systematic visualization of the outflow tract in addition to the four-chamber view. Despite the improvement in prenatal diagnosis, one-third of major CHDs were not screened before birth. Pediatricians still need to diagnose CHDs after birth.
authors: Unité de chirurgie cardiaque pédiatrique, service de médecine pédiatrique, hôpital Clocheville, université François-Rabelais, 49, boulevard Béranger, 37000 Tours, France.
authors: R
authors: R
authors: Bonnefoy
authors: J
authors: J
authors: Poinsot
authors: M-C
authors: MC
authors: Vaillant
authors: A
authors: A
authors: Chantepie
mesh_terms: D005260:Female; D005602:France; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000639:trends*; D012189:Retrospective Studies; D013997:Time Factors; D016216:Ultrasonography, Prenatal