title: [Effect of Campath-1H induction on immunosuppression in small intestine transplantation].
abstract: OBJECTIVE
  To investigate the effect of Campath-1H induction on immunosuppression in small intestine transplantation.
  
  
  METHODS
  Clinical data of a patient who underwent small intestine transplantation were retrospectively summarized.
  
  
  RESULTS
  Intraoperative Campath-1H induction by intravenous injection was administered. Triple immunosuppression(FK506, MMF and methylprednisolone) was used postoperatively. The lymphocyte and leukocyte decreased significantly following Campath-1H induction, and returned to normal after adjusting the dose of immunosuppressant and use of colony stimulating factor. There were no acute rejection, graft versus host disease, or severe infection during the immediate postoperative period. The patient recovered and discharged.
  
  
  CONCLUSIONS
  Intraoperative Campath-1H induction and postoperative triple immunosuppression using FK506, MMF, and methylprednisolone may prevent rejection and graft versus host disease in the early stage after small intestine transplantation.
authors: Organ Transplantation Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. gdtrc@163.com
authors: Jian
authors: J
authors: Zhou
authors: Wei-Qiang
authors: WQ
authors: Ju
authors: Xiao-Shun
authors: XS
authors: He
authors: Dong-Ping
authors: DP
authors: Wang
authors: Xiao-Feng
authors: XF
authors: Zhu
authors: Lin-Wei
authors: LW
authors: Wu
authors: Qiang
authors: Q
authors: Tai
authors: Yi
authors: Y
authors: Ma
authors: An-Bin
authors: AB
authors: Hu
authors: Guo-Dong
authors: GD
authors: Wang
authors: Jie-Fu
authors: JF
authors: Huang
mesh_terms: D000328:Adult; D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007421:Intestine, Small / Q000637:transplantation*; D008297:Male; D012189:Retrospective Studies
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D007166:Immunosuppressive Agents; D000074323:Alemtuzumab