title: Can topical ketorolac 0.5% improve the function of Ahmed® glaucoma drainage devices?
abstract: OBJECTIVE
  To determine whether postoperative use of topical ketorolac tromethamine 0.5% affects intraocular pressure (IOP) following Ahmed glaucoma drainage device (New World Medical, Inc., Rancho Cucamonga, CA) implantation.
  
  
  METHODS
  Patients undergoing Ahmed implantation at the University of Michigan from January 2002 to June 2008 were reviewed. Fourteen eyes received ketorolac after surgery; 50 eyes did not. Preoperative and postoperative IOP and glaucoma medications were recorded for both groups; the two-sided Student's t test was used to compare these parameters.
  
  
  RESULTS
  Mean preoperative IOP was similar in the two groups (35.1 ± 11.9 vs 37.0 ± 12.2 mm Hg; P = .60). At postoperative month 6, the ketorolac group had significantly lower IOP compared with the no ketorolac group (13.1 ± 3.7 vs 19.5 ± 9.3 mm Hg, respectively; P = .0003). There was no difference in the number of glaucoma medications postoperatively between the two groups.
  
  
  CONCLUSIONS
  Ketorolac may lead to lower postoperative IOP following Ahmed implantation.
authors: Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
authors: Garrett R
authors: GR
authors: Scott
authors: Jennifer S
authors: JS
authors: Weizer
authors: Sayoko E
authors: SE
authors: Moroi
authors: Christina A
authors: CA
authors: Bruno
authors: David C
authors: DC
authors: Musch
authors: Leslie M
authors: LM
authors: Niziol
authors: Paul P
authors: PP
authors: Lee
authors: Joshua D
authors: JD
authors: Stein
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D020911:Ketorolac Tromethamine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D020911:Ketorolac Tromethamine