title: Injectable anal bulking agent for the management of faecal incontinence.
abstract: This study was conducted to determine the safety and efficacy of injectable bulking agents. A total of 13 procedures were performed on 11 patients with faecal incontinence during 2002 to 2007. Patients with internal anal sphincter defect and low incontinence score (Cleveland score < 10) revealed improvement. Patients with higher incontinence score and external sphincter defect secondary to obstetric damage required further intervention. At a median follow-up of 43 months, 7 (63%) patients showed improvement in incontinence score and 4 (32%) showed marked improvement in their symptoms. Fifty six percent of the patients described this as an effective procedure, though the level of effectiveness varied from person to person. Anal injectable collagen was found safe and effective in the management of faecal incontinence. Long-term follow-ups are required to re assess and consider definitive procedure in failed cases.
authors: Department of Surgery, Castle Hill Hospital, Cottingham, UK. drsanavri@hotmail.com
authors: Sana
authors: S
authors: Ullah
authors: M
authors: M
authors: Tayyab
authors: Reza
authors: R
authors: Arsalani-Zadeh
authors: G S
authors: GS
authors: Duthie
mesh_terms: D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000002:abnormalities / Q000000981:diagnostic imaging; D003094:Collagen / Q000008:administration & dosage*; D005242:Fecal Incontinence / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D012189:Retrospective Studies; D014463:Ultrasonography
chemical_list: D003094:Collagen