title: Subversion of host cell signaling by Orientia tsutsugamushi.
abstract: Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host interaction. The genome sequencing, microarray and proteomic analyses of this ancient bacterium have provided a wealth of new information. This paper reviews the general characteristics of O. tsutsugamushi and recent developments especially in signaling events involved in the bacteria--host interaction.
authors: Department of Immunology and Pathogen Biology, Tongji University School of Medicine, Shanghai 200092, China. yange.23@gmail.com
authors: Yan
authors: Y
authors: Ge
authors: Yasuko
authors: Y
authors: Rikihisa
mesh_terms: D000818:Animals; D017209:Apoptosis; D001422:Bacterial Adhesion; D058947:Bacterial Secretion Systems / Q000235:genetics; D016207:Cytokines / Q000378:metabolism; D016680:Genome, Bacterial; D054884:Host-Pathogen Interactions / Q000235:genetics / Q000276:immunology*; D006801:Humans; D046228:Microarray Analysis / Q000379:methods; D012285:Orientia tsutsugamushi / Q000235:genetics* / Q000472:pathogenicity*; D040901:Proteomics / Q000379:methods; D012612:Scrub Typhus / Q000235:genetics* / Q000276:immunology; D017421:Sequence Analysis; D015398:Signal Transduction
chemical_list: D058947:Bacterial Secretion Systems; D016207:Cytokines