title: [Why does the cerebral artery aneurysm rupture?].
abstract: Subarachnoid hemorrhage caused by rupture of a cerebral artery aneurysm leads to the death of nearly 500 people in Finland per year. The mechanism of aneurysmal rupture remains unknown at present. It is, however, known that a chronic inflammatory reaction is going on in the aneurysmal wall, being associated with the degeneration of the aneurysmal wall and susceptibility of the aneurysm to bleeding. Unambiguous screening or identification of bleeding-prone aneurysms cannot be performed. The diagnostics and treatment of bleeding-prone aneurysms can possibly be improved in the future by applying imaging of the chronic inflammation and drug therapy.
authors: HYKS:n neurokirurgian tutkimusryhmä, HUS.
authors: Riikka
authors: R
authors: Tulamo
authors: Juhana
authors: J
authors: Frösen
authors: Elisa
authors: E
authors: Laaksamo
authors: Mika
authors: M
authors: Niemelä
authors: Aki
authors: A
authors: Laakso
authors: Juha
authors: J
authors: Hernesniemi
mesh_terms: D017542:Aneurysm, Ruptured / Q000150:complications* / Q000401:mortality; D002536:Cerebral Arteries; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000401:mortality; D002532:Intracranial Aneurysm / Q000150:complications* / Q000401:mortality; D013345:Subarachnoid Hemorrhage / Q000209:etiology* / Q000401:mortality