title: Tubular occlusion of simulated hypersensitive dentin by the combined use of ozone and desensitizing agents.
abstract: OBJECTIVE
  Ozone was suggested for treatment of hypersensitive dentin. The purpose of this study was to investigate the effect of ozone, with or without the use of desensitizing agents, on patency and occlusion of simulated hypersensitive dentin.
  
  
  METHODS
  Sixty standardized dentin slabs were randomly divided into six groups: distilled water (Control), ozone treatment, fluoride desensitizer (ALLSolutions, Dentsply), oxalate desensitizer (D/Sense Crystal, Centrix), combined use of ozone/fluoride and combined use of ozone/oxalate. Ozone gas was delivered from OzonyTronX (Mymed). Specimens were evaluated using a scanning electron microscope and digital image analysis before and after treatment.
  
  
  RESULTS
  Statistical analysis using ANOVA and Mann-Whitney U-tests revealed significantly lower percentage of tubular occlusion with ozone treatment than distilled water at p ≤ 0.05. Scanning electron microscope photomicrographs of oxalate desensitizer specimens revealed a thick homogenous precipitate with significantly higher percentage of tubular occlusion than fluoride desensitizer and distilled water. Combined use of ozone/fluoride resulted in a significantly higher percentage of tubular occlusion than fluoride desensitizer alone. However, no significant difference was found between oxalate desensitizer and combined use of ozone/oxalate.
  
  
  CONCLUSIONS
  The use of ozone gas is a viable adjunct to fluoride-containing desensitizers in enhancing tubular occlusion, but is not effective with oxalate desensitizers.
authors: Department of Operative Dentistry, Faculty of Oral and Dental Medicine, Cairo University, Egypt.
authors: Rasha
authors: R
authors: Raafat Abdelaziz
authors: Rania Sayed
authors: RS
authors: Mosallam
authors: Mai Mahmoud
authors: MM
authors: Yousry
mesh_terms: D000293:Adolescent; D000328:Adult; D011232:Chemical Precipitation; D003460:Crystallization; D003804:Dentin / Q000187:drug effects* / Q000648:ultrastructure; D057133:Dentin Desensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000473:pathology; D004338:Drug Combinations; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008855:Microscopy, Electron, Scanning; D010070:Oxalates / Q000008:administration & dosage / Q000627:therapeutic use; D010083:Oxidants, Photochemical / Q000627:therapeutic use*; D010126:Ozone / Q000627:therapeutic use*; D014867:Water; D055815:Young Adult
chemical_list: C514043:AllSolutions Fluoride Varnish; D057133:Dentin Desensitizing Agents; D004338:Drug Combinations; D005460:Fluorides, Topical; D010070:Oxalates; D010083:Oxidants, Photochemical; D014867:Water; D010126:Ozone