title: Cell growth on in situ photo-cross-linked electrospun acrylated cellulose acetate butyrate.
abstract: In this study, electrospinning was combined with UV curing technology for producing in situ photo cross-linked fibers from methacrylated cellulose acetate butyrate (CABIEM). ECV304 and 3T3 cells were seeded on electrospun fibrous scaffolds. Collagen modified CABIEM fibers were also prepared for improving cell adhesion and proliferation. Cross-linking and the morphology of the fibers were characterized by ATR-FTIR spectrometry and environmental scanning electron microscopy (ESEM). The cytotoxicity of the fibers was examined using the MTT cytotoxicity assay. According to the results, electrospun fibrous scaffolds are non-toxic and cell viability depends on the amount of collagen. It was found that cell adhesion and cell growth were enhanced as the collagen percentage was increased.
authors: a Department of Chemistry, Marmara University, 34722 Goztepe-Istanbul, Turkey.
authors: Emrah
authors: E
authors: Çakmakçı
authors: Atilla
authors: A
authors: Güngör
authors: Nilhan
authors: N
authors: Kayaman-Apohan
authors: Serap Erdem
authors: SE
authors: Kuruca
authors: Muzaffer Beyza
authors: MB
authors: Çetin
authors: Kadriye Akgün
authors: KA
authors: Dar
mesh_terms: D016475:3T3 Cells; D000818:Animals; D002448:Cell Adhesion; D002460:Cell Line; D002465:Cell Movement; D002470:Cell Survival; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000528:radiation effects; D042783:Endothelial Cells / Q000502:physiology; D006801:Humans; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D051379:Mice; D008855:Microscopy, Electron, Scanning; D011092:Polyethylene Glycols / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry; D014466:Ultraviolet Rays
chemical_list: D008689:Methacrylates; C524499:polyethylene glycol methacrylate; D011092:Polyethylene Glycols; D002482:Cellulose; C014396:cellulose acetate-butyrate