title: Environmental enrichment reduces the likelihood of alopecia in adult C57BL/6J mice.
abstract: Barbering (incessant grooming) is an abnormal behavior causing alopecia and commonly affects various strains of laboratory mice, including C57BL/6J. Barbering-induced alopecia is a potential symptom of brain impairment and can indicate a stressful environment. We compared alopecia prevalence and severity in mice housed in enriched or standard cages. Providing an enriched environment delayed the onset and reduced the prevalence and overall severity of alopecia in C57BL/6J mice. Husbandry methods that reduce adult alopecia are likely to promote the wellbeing of the animals. We suggest that environmental enrichment is a simple and economic way to reduce alopecia in mouse colonies.
authors: Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada. abechard@uoguelph.ca
authors: Allison
authors: A
authors: Bechard
authors: Rebecca
authors: R
authors: Meagher
authors: Georgia
authors: G
authors: Mason
mesh_terms: D000505:Alopecia / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D000822:Animal Husbandry / Q000191:economics; D000818:Animals; D005260:Female; D006120:Grooming; D006799:Housing, Animal; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D015995:Prevalence; D012376:Rodent Diseases / Q000453:epidemiology / Q000517:prevention & control*; D013312:Stress, Physiological