title: Severe symptomatic hyponatremia--an uncommon presentation of tacrolimus nephrotoxicity.
abstract: Though tacrolimus-induced nephrotoxicity and hyperkalemia are well known, severe symptomatic hyponatremia is not commonly documented with its use. Here, we report a case of severe symptomatic hyponatremia in a renal transplant recipient on tacrolimus despite normal tacrolimus trough level. All other potential causes of hyponatremia were ruled out in this patient. This case highlights an uncommon aspect of tacrolimus nephrotoxicity, which we should keep in mind while following up a renal transplant recipient.
authors: Division of Nephrology, Department of Medicine, National University Hospital, Singapore. soumita_bagchi@yahoo.co.in
authors: Soumita
authors: S
authors: Bagchi
authors: Sabahat
authors: S
authors: Husain Zaidi
authors: Rajendra
authors: R
authors: Prasad Mathur
mesh_terms: D000328:Adult; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D016559:Tacrolimus / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus