title: Assessment of left ventricular function and volume in patients undergoing 128-slice coronary CT angiography with ECG-based maximum tube current modulation: a comparison with echocardiography.
abstract: OBJECTIVE
  To compare multi-detector CT (MDCT) using 128-slice coronary CT angiography (Definition AS+, Siemens Medical Solution, Forchheim, Germany) with ECG-based maximum tube current modulation with echocardiography for the determination of left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), end-systolic volume (ESV), as well as assessing coronary artery image quality and patient radiation dose.
  
  
  METHODS
  Thirty consecutive patients (M:F = 20:10; mean age, 57.9 ± 11.4 years) were referred for MDCT for evaluation of atypical chest pain. EF, EDV and ESV were determined for both MDCT and echocardiography, and the correlation coefficients were assessed. Coronary artery segment subjective image quality (1, excellent; 4, poor) and radiation dose were recorded.
  
  
  RESULTS
  Left ventricular EF, EDV, and ESV were calculated by MDCT and echocardiography and the comparison showed a significant correlation with those estimated by echocardiography (p < 0.05). Consistently, the LVEFs calculated by MDCT and echocardiography were not statistically different. However, LV, EDV and ESV from MDCT were statistically higher than those from echocardiography (p < 0.05). The average image quality score of the coronary artery segment was 1.10 and the mean patient radiation dose was 3.99 ± 1.85 mSv.
  
  
  CONCLUSIONS
  Although LV volume was overestimated by MDCT, MDCT provides comparable results to echocardiography for LVEF and LVV, with a low radiation dose.
authors: Department of Cardiology, Kim Hae Jungang Hospital, Gyeongsangnam-do 621-921, Korea.
authors: Soo Jin
authors: SJ
authors: Lim
authors: Ki Seok
authors: KS
authors: Choo
authors: Yong Hyun
authors: YH
authors: Park
authors: Jeong Su
authors: JS
authors: Kim
authors: June Hong
authors: JH
authors: Kim
authors: Kook Jin
authors: KJ
authors: Chun
authors: Dong Wook
authors: DW
authors: Jeong
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D003971:Diastole; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D013318:Stroke Volume; D013599:Systole; D014057:Tomography, X-Ray Computed; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*