title: Lamotrigine treatment of a patient affected by epilepsy and anxiety disorder.
abstract: Epilepsy often occurs in comorbidity with mental diseases and disorders. Early detection and/or treatment of such disorders in patients affected by epilepsy, as well as their socialisation are crucially important since epileptic patients tend to suffer more due to lack of social support than to frequent epileptic seizures. Prevalence of psychiatric disorders is higher in patients with epilepsy than in general population, the most frequent being: anxiety, depression, panic attacks, behavioural disorders as well as psychotic states with paranoid elements. The efficacy of AE treatment of patients affected by epilepsy and mood disorders has also directed clinicians to investigate possible AE benefits in treating other mental disorders such as anxiety states, depression and bipolar disorder. The examined case displays complex partial epilepsy and comorbid mental disorder. The use of lamotrigine, a fourth-generation antiepileptic, which is also a mood stabilizer, has assured a favourable remission of symptoms related to both epilepsy and mood disorders. Side-effects caused by lamotrigine were only temporary and dose reduction was sufficient to eliminate their symptoms.
authors: Policlinic for Neurology and Psychiatry Interneuron, 51000 Rijeka, Croatia. poliklinika.interneuron@ri.t-com.hr
authors: Dubravka
authors: D
authors: Sepić-Grahovac
authors: Tanja
authors: T
authors: Grahovac
authors: Antonija
authors: A
authors: Ružić-Baršić
authors: Klementina
authors: K
authors: Ružić
authors: Elizabeta
authors: E
authors: Dadić-Hero
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D015897:Comorbidity; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004834:Epilepsy, Post-Traumatic / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D005500:Follow-Up Studies; D006801:Humans; D000077213:Lamotrigine; D008297:Male; D014227:Triazines / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000927:Anticonvulsants; D014227:Triazines; D000077213:Lamotrigine