title: On the use of computed radiography plates for quality assurance of intensity modulated radiation therapy dose distributions.
abstract: OBJECTIVE
  As traditional film is phased out in most radiotherapy centers, computed radiography (CR) systems are increasingly being purchased as a replacement. CR plates can be used for patient imaging, but may also be used for a variety of quality assurance (QA) purposes and can be calibrated in terms of dose. This study looks at their suitability for verification of intensity modulated radiation therapy (IMRT) dose distributions.
  
  
  METHODS
  A CR plate was calibrated in terms of the relative dose and the stability of response over 1 year was studied. The effect of exposing the CR plate to ambient light and of using different time delays before scanning was quantified. The CR plate was used to verify the relative dose distributions for ten IMRT patients and the results were compared to those obtained using a two dimensional (2D) diode array.
  
  
  RESULTS
  Exposing the CR plate to 10 s of ambient light between irradiation (174 cGy) and scanning erased approximately 80% of the signal. Changes in delay time between irradiation and scanning also affected the measurement results. The signal on the plate was found to decay at a rate of approximately 3.6 cGy/min in the first 10 min after irradiation. The use of a CR plate for IMRT patient-specific QA resulted in a significantly lower distance to agreement (DTA) and gamma pass rate than when using a 2D diode array for the measurement. This was primarily due to the over-response of the CR phosphor to low energy scattered radiation. For the IMRT QA using the CR plate, the average gamma pass rate was 97.3%. For the same IMRT QA using a diode array, the average gamma pass rate was 99.7%. The gamma criteria used were 4% dose difference and 4 mm DTA for head and neck treatments and 3% dose difference and 3 mm DTA for prostate treatments. The gamma index tolerance was 1. The lowest 10% of the dose distribution was excluded from all gamma and DTA analyses.
  
  
  CONCLUSIONS
  Although the authors showed that CR plates can be used for patient specific IMRT QA, the practical problems such as the over-response to low energy scatter and signal fading with light exposure and time mean that alternative detectors such as radiochromic film or diode arrays will be a more sensible choice for most radiotherapy departments.
authors: Department of Oncology Physics, Edinburgh Cancer Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, United Kingdom. r.day@nhs.net
authors: R A
authors: RA
authors: Day
authors: A P
authors: AP
authors: Sankar
authors: W H
authors: WH
authors: Nailon
authors: A S
authors: AS
authors: MacLeod
mesh_terms: D006801:Humans; D019047:Phantoms, Imaging; D011786:Quality Control; D011829:Radiation Dosage; D011879:Radiotherapy Dosage; D011881:Radiotherapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation / Q000379:methods* / Q000592:standards*; D015203:Reproducibility of Results; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods*