title: A retrospective assessment of occupational exposure to elemental carbon in the U.S. trucking industry.
abstract: BACKGROUND
  Despite considerable epidemiologic evidence about the health effects of chronic exposure to vehicle exhaust, efforts at defining the extent of risk have been limited by the lack of historical exposure measurements suitable for use in epidemiologic studies and for risk assessment.
  
  
  OBJECTIVE
  We sought to reconstruct exposure to elemental carbon (EC), a marker of diesel and other vehicle exhaust exposure, in a large national cohort of U.S. trucking industry workers.
  
  
  METHODS
  We identified the predictors of measured exposures based on a statistical model and used this information to extrapolate exposures across the cohort nationally. These estimates were adjusted for changes in work-related conditions over time based on a previous exposure assessment of this industry, and for changes in background levels based on a trend analysis of historical air pollution data, to derive monthly estimates of EC exposure for each job and trucking terminal combination between 1971 and 2000.
  
  
  RESULTS
  Occupational exposure to EC declined substantially over time, and we found significant variability in estimated exposures both within and across job groups, trucking terminals, and regions of the United States. Average estimated EC exposures during a typical work shift ranged from < 1 μg/m³ in the lowest exposed category in the 1990s to > 40 μg/m³ for workers in the highest exposed jobs in the 1970s.
  
  
  CONCLUSIONS
  Our results provide a framework for understanding changes over time in exposure to EC in the U.S. trucking industry. Our assessment should minimize exposure misclassification by capturing variation among terminals and across U.S. regions, and changes over time.
authors: Department of Urban and Environmental Policy and Planning, Tufts University, Medford, Massachusetts 02115, USA. mary.davis@tufts.edu
authors: Mary E
authors: ME
authors: Davis
authors: Jaime E
authors: JE
authors: Hart
authors: Francine
authors: F
authors: Laden
authors: Eric
authors: E
authors: Garshick
authors: Thomas J
authors: TJ
authors: Smith
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000032:analysis*; D002244:Carbon / Q000032:analysis*; D015331:Cohort Studies; D004781:Environmental Exposure / Q000145:classification; D006801:Humans; D008297:Male; D008954:Models, Biological; D018986:Motor Vehicles; D016273:Occupational Exposure; D012189:Retrospective Studies; D013997:Time Factors; D014481:United States; D001335:Vehicle Emissions / Q000032:analysis*
chemical_list: D000395:Air Pollutants, Occupational; D001335:Vehicle Emissions; D002244:Carbon