title: The use of a powdered polysaccharide hemostat (HemoStase) in live donor nephrectomies controls bleeding and reduces postoperative complications.
abstract: OBJECTIVE
  This study assesses the use of microporous hemospheres (hemoStase) procedures to control bleeding and reduce associated unfavorable sequelae in live donor nephrectomy (LDN).
  
  
  METHODS
  Forty-four consecutive patients who underwent LDN between January 2009 and August 2009 were included in this prospective study. HemoStase (CryoLife, Inc), Kennesaw, Georgia) was used topically in the kidney bed to avoid bleeding. We recorded intraoperative and postoperative bleeding control, re-exploration to control bleeding, surgical site fluid collection, infection, and postoperative wound complications.
  
  
  RESULTS
  Hemostasis was achieved in all 44 (100%) patients, none of whom experienced postoperative bleeding, fluid collection, infection or required re-exploration of the surgical site.
  
  
  CONCLUSIONS
  HemoStase is a safe, facile hemostatic agent that effectively controls bleeding and reduces associated postoperative complications in LDN cases.
authors: West London Renal and Transplant Centre, Imperial College Health Care NHS Trust, and Transplant Unit, Hammersmith Hospital, London, UK.
authors: P
authors: P
authors: Rajagopal
authors: N
authors: N
authors: Hakim
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006470:Hemorrhage; D006490:Hemostatics / Q000494:pharmacology*; D006801:Humans; D007668:Kidney / Q000187:drug effects; D007676:Kidney Failure, Chronic / Q000628:therapy; D016030:Kidney Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011134:Polysaccharides / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D014945:Wound Healing
chemical_list: D006490:Hemostatics; D011134:Polysaccharides