title: Blood concentrations of chlorhexidine in hospitalized children undergoing daily chlorhexidine bathing.
abstract: We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.
authors: Department of Internal Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors: Andrew
authors: A
authors: Lee
authors: Robert
authors: R
authors: Harlan
authors: Autumn R
authors: AR
authors: Breaud
authors: Kathleen
authors: K
authors: Speck
authors: Trish M
authors: TM
authors: Perl
authors: William
authors: W
authors: Clarke
authors: Aaron M
authors: AM
authors: Milstone
mesh_terms: D000293:Adolescent; D000890:Anti-Infective Agents / Q000097:blood* / Q000493:pharmacokinetics* / Q000627:therapeutic use; D001494:Baths; D002648:Child; D002675:Child, Preschool; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D057230:Limit of Detection; D008297:Male; D012869:Skin Absorption
chemical_list: D000890:Anti-Infective Agents; C010882:chlorhexidine gluconate; D002710:Chlorhexidine