title: Symptoms of agitated depression and/or akathisia.
abstract: Akathisia is a syndrome characterized by the unpleasant sensation of "inner" restlessness that manifests itself in the inability of sitting still or not moving. Many types of medicaments can cause akathisia as an adverse event of their use and they include: antipsychotics, antidepressants, antiemetics, antihistamines, and psychoactive substances. We will present the case of a 50 year old patient, treated on two occasions for psychotic depression. During the second hospitalization it is possible that antipsychotic treatment combined with an antidepressant caused akathisia or there were symptoms of agitated depression and akathisia present at the same time, which is very difficult to determine in everyday clinical practice. We can conclude that in this case, as in many others, akathisia as a possible adverse effect of psychopharmacs was very hard to identify. Therefore, it is necessary to have akathisia in mind when using certain medicaments, especially when combining several that use the same enzymatic system and consequently raise levels of at least one of them.
authors: Psychiatric Clinic of University Hospital Centre Rijeka, Cambierieva 17/7, 51000 Rijeka, Croatia. marijavp@gmail.com
authors: Marija Vučić
authors: MV
authors: Peitl
authors: Joško
authors: J
authors: Prološčić
authors: Sandra
authors: S
authors: Blažević-Zelić
authors: Ivona
authors: I
authors: Skarpa-Usmiani
authors: Vjekoslav
authors: V
authors: Peitl
mesh_terms: D000341:Affective Disorders, Psychotic / Q000175:diagnosis* / Q000188:drug therapy* / Q000523:psychology; D017109:Akathisia, Drug-Induced / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D000927:Anticonvulsants / Q000627:therapeutic use; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy* / Q000523:psychology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D003987:Dibenzothiazepines / Q000627:therapeutic use; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D016666:Fluvoxamine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D011595:Psychomotor Agitation / Q000175:diagnosis* / Q000188:drug therapy* / Q000523:psychology; D000069348:Quetiapine Fumarate; D014635:Valproic Acid / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D018687:Antidepressive Agents, Second-Generation; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D001569:Benzodiazepines; D000069348:Quetiapine Fumarate; D014635:Valproic Acid; D000077152:Olanzapine; D016666:Fluvoxamine