title: Novel one-pot process for the synthesis of 1,3-thiazoles via organocatalysed epoxidation of nitro-olefins.
abstract: A facile one-pot two-step process for the synthesis of 1,3-thiazole heterocycles via organocatalytic epoxidation of nitro-olefins with the t-BuOOH/DBU system, and subsequent reaction of α-nitro-epoxides with thioamides under mild conditions has been developed.
authors: Department of Chemistry and Pharmacy, Institute of Organic Chemistry 1, University of Erlangen-Nuremberg, Henkestrasse 42, 91054, Erlangen, Germany.
authors: Katharina M
authors: KM
authors: Weiss
authors: Shengwei
authors: S
authors: Wei
authors: Svetlana B
authors: SB
authors: Tsogoeva
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D013844:Thiazoles / Q000138:chemical synthesis*
chemical_list: D000475:Alkenes; D004852:Epoxy Compounds; D009570:Nitriles; D013844:Thiazoles