title: Simultaneous DSC-FTIR microspectroscopy used to screen and detect the co-crystal formation in real time.
abstract: We first report that the formation of pharmaceutical co-crystal can be synchronously screened and confirmed by a simultaneous DSC-FTIR microspectroscopic system, in which this combined unique system giving spectroscopic and thermodynamic information could provide a easy and direct way for one step screening and qualitative detection of the co-crystal formation in real time.
authors: Department of Biotechnology, Yuanpei University, Hsin-Chu, Taiwan.
authors: Tieh-Kang
authors: TK
authors: Wu
authors: Shan-Yang
authors: SY
authors: Lin
authors: Hong-Liang
authors: HL
authors: Lin
authors: Yu-Ting
authors: YT
authors: Huang
mesh_terms: D002152:Calorimetry, Differential Scanning; D003460:Crystallization; D015394:Molecular Structure; D017550:Spectroscopy, Fourier Transform Infrared; D013816:Thermodynamics