title: Kodamaea ohmeri as an emerging pathogen: a case report and review of the literature.
abstract: Kodamaea (Pichia) ohmeri is a yeast-like fungus that has recently emerged as an important etiologic agent of fungemia in immunocompromised patients. We report such a case in a premature neonate born at 29 weeks of gestation. Prior to developing fungemia, she had two episodes of bacterial sepsis on day 13 and day 32 due to Enterobacter cloacae and Staphylococcus epidermidis, respectively. Kodamaea ohmeri was repeatedly isolated from blood cultures and its identity was determined by phenotypic characteristics and sequencing of the ITS and D1/D2 regions of rDNA. The neonate was successfully treated with amphotericin B. The published cases of K. ohmeri fungemia reported in pediatric patients are reviewed highlighting its increasing importance as a bloodstream pathogen.
authors: Department of Microbiology, Faculty of Medicine, Kuwait University, Shuwaikh, Kuwait.
authors: Noura
authors: N
authors: Al-Sweih
authors: Zia U
authors: ZU
authors: Khan
authors: Suhail
authors: S
authors: Ahmad
authors: Laxmi
authors: L
authors: Devarajan
authors: Seema
authors: S
authors: Khan
authors: Leena
authors: L
authors: Joseph
authors: Rachel
authors: R
authors: Chandy
mesh_terms: D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D021821:Communicable Diseases, Emerging / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D016972:Enterobacter cloacae / Q000302:isolation & purification; D005260:Female; D016469:Fungemia / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D016533:Mycological Typing Techniques; D010802:Phylogeny; D004718:Saccharomycetales / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D013212:Staphylococcus epidermidis / Q000302:isolation & purification; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D000666:Amphotericin B