title: A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines.
abstract: The Sandmeyer reaction of differently C-2 substituted N-(prop-2-yn-1-ylamino)pyridines is an efficient, mild, new and practical method for the stereospecific synthesis of (E)-exo-halomethylene bicyclic pyridones bearing the imidazo[1,2-a]pyridine heterocyclic ring system.
authors: Laboratorio de Radicales Libres y Química Computacional, IQOG (CSIC), Juan de la Cierva, 3, 28006-Madrid, Spain.
authors: David
authors: D
authors: Sucunza
authors: Abdelouahid
authors: A
authors: Samadi
authors: Mourad
authors: M
authors: Chioua
authors: Daniel B
authors: DB
authors: Silva
authors: Cristina
authors: C
authors: Yunta
authors: Lourdes
authors: L
authors: Infantes
authors: M
authors: M
authors: Carmo Carreiras
authors: Elena
authors: E
authors: Soriano
authors: José
authors: J
authors: Marco-Contelles
mesh_terms: D000588:Amines / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis*; D003500:Cyclization; D007093:Imidazoles / Q000138:chemical synthesis*; D011725:Pyridines / Q000138:chemical synthesis*; D011728:Pyridones / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000588:Amines; D001688:Biological Products; D019086:Bridged Bicyclo Compounds, Heterocyclic; D007093:Imidazoles; D011725:Pyridines; D011728:Pyridones