title: Predicting individual affect of health interventions to reduce HPV prevalence.
abstract: Recently, human papilloma virus (HPV) has been implicated to cause several throat and oral cancers and HPV is established to cause most cervical cancers. A human papilloma virus vaccine has been proven successful to reduce infection incidence in FDA clinical trials, and it is currently available in the USA. Current intervention policy targets adolescent females for vaccination; however, the expansion of suggested guidelines may extend to other age groups and males as well. This research takes a first step toward automatically predicting personal beliefs, regarding health intervention, on the spread of disease. Using linguistic or statistical approaches, sentiment analysis determines a text's affective content. Self-reported HPV vaccination beliefs published in web and social media are analyzed for affect polarity and leveraged as knowledge inputs to epidemic models. With this in mind, we have developed a discrete-time model to facilitate predicting impact on the reduction of HPV prevalence due to arbitrary age- and gender-targeted vaccination schemes.
authors: Pacific Northwest National Laboratory, Richland, WA, USA. court@pnl.gov
authors: Courtney D
authors: CD
authors: Corley
authors: Rada
authors: R
authors: Mihalcea
authors: Armin R
authors: AR
authors: Mikler
authors: Antonio P
authors: AP
authors: Sanfilippo
mesh_terms: D000293:Adolescent; D000328:Adult; D019295:Computational Biology; D057225:Data Mining; D005260:Female; D006801:Humans; D008297:Male; D015233:Models, Statistical; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000494:pharmacology; D015995:Prevalence; D011634:Public Health; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines