title: [Acute flank pain syndrome: a common presentation of acute renal failure in young men in Iceland].
abstract: The purpose of the study was to calculate the incidence of the acute flank pain syndrome in Iceland and to describe the case series.
  
  
  
  The hospital records of those who fulfilled the following criteria were studied: age 18-41 years, acute renal failure, and a visit to Landspitali University Hospital in 1998-2007. The acute flank pain syndrome was defined as severe flank pain in combination with acute renal failure, unexplained except for the possible consumption of NSAIDs, ethanol or both. Information was collected about the sales of NSAIDs.
  
  
  
  One hundred and six patients had acute renal failure. Of those, 21 had the acute flank pain syndrome (20%). The annual incidence of the acute flank pain syndrome increased threefold during the study period. The average incidence was 3.2/100.000/year (relative to the population of the Reykjavik area) and 2.0/100.000/year (relative to the population of Iceland). 18 patients were male and the median age was 26 (19-35) years. The symptoms regressed spontaneously during a few days or weeks. There was history of NSAID intake in 15, ethanol consumption in 15, either in 20, and both in nine patients. The sales figures of NSAIDs were high and they increased during the study period, especially those of the over-the-counter sales of ibuprofen.
  
  
  
  The incidence of the acute flank pain syndrome was high. The paper describes the largest case series that has been published since the withdrawal of suprofen in 1987. Young people should be warned about consuming NSAIDs during or directly after binge drinking.
authors: Lyflækningadeild, Karolinska háskólasjúkrahúsinu, Stokkhólmi, (áður lyflækningasviði Landspítala).
authors: Helga Margret
authors: HM
authors: Skuladottir
authors: Margret Birna
authors: MB
authors: Andresdottir
authors: Sverrir
authors: S
authors: Hardarson
authors: Margret
authors: M
authors: Arnadottir
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000453:epidemiology*; D000328:Adult; D000367:Age Factors; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D021501:Flank Pain / Q000453:epidemiology*; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D015994:Incidence; D008297:Male; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D013577:Syndrome; D013997:Time Factors; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal