title: Recombinant Mycobacterium smegmatis vaccine candidates.
abstract: Mycobacterium smegmatis is a species of rapidly growing saprophytes with a number of properties that make it an effective vaccine vector. Recombinant M. smegmatis expressing protective antigens of different pathogens and molecules modulating the immune responses offers some potential for reduction of the burden of tuberculosis, HIV and hepatitis B infections. This paper discusses the molecular methods used to generate recombinant M. smegmatis and the results obtained with some of these recombinants.
authors: University of Szeged, Department of Medical Microbiology and Immunobiology, Szeged, Hungary. faludi.ildiko@gmail.com
authors: Ildikó
authors: I
authors: Faludi
authors: Agnes Míra
authors: AM
authors: Szabó
authors: Katalin
authors: K
authors: Burián
authors: Valéria
authors: V
authors: Endrész
authors: A
authors: A
authors: Miczák
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D015488:HIV Antigens / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D006801:Humans; D020102:Mycobacterium smegmatis / Q000235:genetics* / Q000276:immunology*; D014169:Transformation, Bacterial / Q000235:genetics* / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000235:genetics* / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D015488:HIV Antigens; D014614:Vaccines, Synthetic