title: Incidence, predictors and associated outcomes of renal cell carcinoma in long-term dialysis patients.
abstract: We carried out an analysis of the United States Renal Data System to determine the incidence, risk factors and prognosis of renal cell carcinoma (RCC) in a national population of patients receiving incident long-term dialysis. In Cox regression, male gender, older age, end-stage renal disease caused by obstruction, tuberous sclerosis, focal segmental glomerulosclerosis, as well as acquired renal cysts, were independently associated with RCC. Most cases of RCC in incident long-term dialysis patients occurred in patients without acquired renal cysts. A diagnosis of RCC was associated with increased risk of subsequent mortality overall and in all high-risk groups.
authors: Nephrology Service, Walter Reed Army Medical Center, Washington, DC 20307, USA.
authors: Frank P
authors: FP
authors: Hurst
authors: Rahul M
authors: RM
authors: Jindal
authors: James J
authors: JJ
authors: Fletcher
authors: Vikas
authors: V
authors: Dharnidharka
authors: Greg
authors: G
authors: Gorman
authors: Brent
authors: B
authors: Lechner
authors: Robert
authors: R
authors: Nee
authors: Lawrence Y
authors: LY
authors: Agodoa
authors: Kevin C
authors: KC
authors: Abbott
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003560:Cysts / Q000150:complications; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000150:complications; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D006278:Medicare; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D016016:Proportional Hazards Models; D006435:Renal Dialysis / Q000379:methods; D012307:Risk Factors; D012737:Sex Factors; D014402:Tuberous Sclerosis / Q000150:complications; D014481:United States