title: A case report: metastatic choriocarcinoma to the gum.
abstract: Choriocarcinoma is a rare neoplasia with a tendency of distant metastasis although highly sensitive to chemotherapy renders a good prognosis and outcome. Lungs, liver and cerebral metastasis are commonly implicated with maxillofacial region rarely involved. We illustrate a case of overwhelming metastatic choriocarcinoma to lungs, liver, brain and to the extreme of gum metastasis. Decompressive craniectomy for intracranial bleeding, multiple transfusions to correct anaemia and coagulopathy were done before high-risk-regime chemotherapy. Despite this, due to fulminant multi-organs involvement she finally succumbed to death. In conclusion, gum bleeding in choriocarcinoma may suggest metastasis and poor prognosis.
authors: The Department of Obstetrics and Gynaecology, Faculty of Medicine, UKM Medical Centre, Kuala Lumpur, Malaysia. mns@ppukm.ukm.my
authors: Mohamad Nasir
authors: MN
authors: Shafiee
authors: Norazlin Mohamed
authors: NM
authors: Ismail
authors: Lim Pei
authors: LP
authors: Shan
authors: Nirmala
authors: N
authors: Kampan
authors: Mohd Hashim
authors: MH
authors: Omar
authors: Hatta Mohd
authors: HM
authors: Dali
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary; D002822:Choriocarcinoma / Q000188:drug therapy / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005887:Gingival Neoplasms / Q000150:complications / Q000188:drug therapy / Q000556:secondary*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D009102:Multiple Organ Failure; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000473:pathology*; D055815:Young Adult