title: [The use of cardiac markers bed test in acute coronary syndrome in emergency department].
abstract: OBJECTIVE
  The evaluation of the patient with chest pain in the emergency department is one of the most common situations that the doctor has to face. The diagnostic procedure supposes an observation period of at least 6-12 hours, a well organized medical facilities and the identification of all SCA cases to reduce inappropriate admission.
  
  
  METHODS
  In our study we have estimated the utility of the marker assay that is associated to the use of risk scores (TIMI and GRACE risk score) to obtain indication about the most appropriate assistance level. In particular, we used the assay of necrosis markers to highlight the damage along with the assay of natriuretic peptides for their role in the diagnosis and in the monitoring of the patients with cardiac damage.
  
  
  RESULTS
  Also PCR has an important role such as marker of plaque stability and of inflammation. These markers associated to the necrosis markers could give important clinical information of independent nature.
  
  
  CONCLUSIONS
  The sensibility of laboratory markers, without important necrosis, is low and it is not possible to exclude in a few time a SCA There is now an alternative strategy: a precocious risk stratification. Using clinical criteria it is possible to do a first evaluation of the probability of SCA and the complications.
authors: Dipartimento di Emergenza, Policlinico Umberto I, "Sapienza" Università di Roma, Italia. marianna.suppa@uniroma1.it
authors: M
authors: M
authors: Suppa
authors: C
authors: C
authors: Boccardo
authors: F
authors: F
authors: Cavicchi
authors: E
authors: E
authors: Contu
authors: L
authors: L
authors: Valeriani
authors: M
authors: M
authors: Colzi
authors: G
authors: G
authors: Giancaspro
authors: M G
authors: MG
authors: Scarpellini
authors: A
authors: A
authors: Coppola
authors: E
authors: E
authors: Baldini
authors: F
authors: F
authors: Aguglia
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000473:pathology; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002637:Chest Pain / Q000209:etiology; D052279:Creatine Kinase, MB Form / Q000097:blood*; D004636:Emergency Service, Hospital; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009211:Myoglobin / Q000097:blood*; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D019095:Point-of-Care Systems; D011237:Predictive Value of Tests; D011379:Prognosis; D012306:Risk; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D009211:Myoglobin; D019210:Troponin I; C036309:fibrin fragment D; D020097:Natriuretic Peptide, Brain; D052279:Creatine Kinase, MB Form