title: [Human health effects of ultrafine particles].
abstract: Epidemiologic and clinical studies have linked elevated concentrations of ambient ultrafine particles (UFPs) to adverse health effects. In particular, has been demonstrated an association between UFPs exposure and occurrence of acute respiratory infections, lung cancer, chronic chronic obstructive pulmonary diseases and cardiovascular diseases. Although the biological mechanisms behind these associations are not fully understood, the results of in vitro toxicological research have shown that UFPs induces several types of adverse cellular effects, including cytotoxicity, mutagenicity, DNA oxidative damage and stimulation of proinflammatory cytokine production. In this reviewer are summarized the results of the recent epidemiological and toxicological studies on adverse health effects from exposure to UFPs.
authors: Dipartimento di Medicina Sperimentale, Sezione di Medicina del Lavoro, Igiene e Tossicologia Industriale, Seconda Università degli Studi di Napoli. nicola.sannolo@unina2.it
authors: N
authors: N
authors: Sannolo
authors: M
authors: M
authors: Lamberti
authors: P
authors: P
authors: Pedata
mesh_terms: D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D052638:Particulate Matter / Q000009:adverse effects*
chemical_list: D052638:Particulate Matter