title: [Oxidation stress role in age-related cataractogenesis].
abstract: BACKGROUND
  Age-related cataract not only diminishes human life quality but it also represents a big impact on healthcare budget of almost every country as the population ages globally. Hence, cataract prevention is a big and true challenge, but a very difficult task to be accomplished. Nowadays cataract is more than a routinely recognized and almost always successfully operated ophthalmologic disease. The diagnosis of age-related cataract diagnosis might alert doctors to some systemic disorders on the whole body level. Increasing age is certainly the most essential age-related cataract risk factor. However, it seems that cataract could be a multifactor disease because of its individual, familiar, racial and gender expression differences.
  Oxidation stress and its form caused by ultraviolet light- photo-oxidative stress--are considered to be crucial in the etiopathogenesis of cataract. All biomolecules suffer damages during cataract formation. On the other side, the lens possess a range of antioxidant elements and mechanisms of their action, which enable long lasting maintenance of lens transparency and functioning. Although they are primary characteristics of the lens, these antioxidant elements also depend on their systemic availability and consumption. This paper is a short literature review of the relation between oxidation stress and age-related cataract.
authors: Klinika za ocne bolesti, Bolnicki centar Kosovska Mitrovica. lepsaz@eunet.rs
authors: Lepsa
authors: L
authors: Zorić
authors: Emina
authors: E
authors: Colak
authors: Vladimir
authors: V
authors: Canadanović
authors: Natalija
authors: N
authors: Kosanović-Jaković
authors: Bojana
authors: B
authors: Kisić
mesh_terms: D000368:Aged; D000375:Aging / Q000378:metabolism*; D002386:Cataract / Q000209:etiology / Q000378:metabolism* / Q000517:prevention & control; D006801:Humans; D018384:Oxidative Stress; D014466:Ultraviolet Rays / Q000009:adverse effects