title: The FaceBase Consortium: a comprehensive program to facilitate craniofacial research.
abstract: The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics hub. Funded by the National Institute of Dental and Craniofacial Research (NIDCR) and currently focused on studying the development of the middle region of the face, the Consortium will produce comprehensive datasets of global gene expression patterns, regulatory elements and sequencing; will generate anatomical and molecular atlases; will provide human normative facial data and other phenotypes; conduct follow up studies of a completed genome-wide association study; generate independent data on the genetics of craniofacial development, build repositories of animal models and of human samples and data for community access and analysis; and will develop software tools and animal models for analyzing and functionally testing and integrating these data. The FaceBase website (http://www.facebase.org) will serve as a web home for these efforts, providing interactive tools for exploring these datasets, together with discussion forums and other services to support and foster collaboration within the craniofacial research community.
authors: Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15232, USA.
authors: Harry
authors: H
authors: Hochheiser
authors: Bruce J
authors: BJ
authors: Aronow
authors: Kristin
authors: K
authors: Artinger
authors: Terri H
authors: TH
authors: Beaty
authors: James F
authors: JF
authors: Brinkley
authors: Yang
authors: Y
authors: Chai
authors: David
authors: D
authors: Clouthier
authors: Michael L
authors: ML
authors: Cunningham
authors: Michael
authors: M
authors: Dixon
authors: Leah Rae
authors: LR
authors: Donahue
authors: Scott E
authors: SE
authors: Fraser
authors: Benedikt
authors: B
authors: Hallgrimsson
authors: Junichi
authors: J
authors: Iwata
authors: Ophir
authors: O
authors: Klein
authors: Mary L
authors: ML
authors: Marazita
authors: Jeffrey C
authors: JC
authors: Murray
authors: Stephen
authors: S
authors: Murray
authors: Fernando Pardo-Manuel
authors: FP
authors: de Villena
authors: John
authors: J
authors: Postlethwait
authors: Steven
authors: S
authors: Potter
authors: Linda
authors: L
authors: Shapiro
authors: Richard
authors: R
authors: Spritz
authors: Axel
authors: A
authors: Visel
authors: Seth M
authors: SM
authors: Weinberg
authors: Paul A
authors: PA
authors: Trainor
mesh_terms: D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D005145:Face / Q000196:embryology*; D020869:Gene Expression Profiling; D006801:Humans; D012106:Research; D012886:Skull / Q000196:embryology*; D012984:Software