title: Mastocytosis and diffuse large B-cell lymphoma, an unlikely combination.
abstract: Systemic mastocytosis may be accompanied by a second haematological malignancy, usually of myeloid origin. However, a number of case reports describe systemic mastocytosis coexisting with a second haematological malignancy of lymphoid origin. Here, we report a case of a 74-year-old man with systemic mastocytosis who developed a diffuse large B-cell lymphoma. A short overview of the literature concerning mastocytosis accompanied by a second haematological malignancy is presented.
authors: Department of Internal Medicine, Reinier de Graaf Gasthuis, Delft, The Netherlands. SchipN@rdgg.nl
authors: E M
authors: EM
authors: Schipper
authors: W
authors: W
authors: Posthuma
authors: I
authors: I
authors: Snieders
authors: R E
authors: RE
authors: Brouwer
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000188:drug therapy; D008297:Male; D034721:Mastocytosis, Systemic / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage; D000069283:Rituximab
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone