title: Lycopodium alkaloids: isolation and asymmetric synthesis.
abstract: Lycopodium alkaloids have attracted the attention of many natural product chemists and synthetic organic chemists due to their important biological activities and unique skeletal characteristics. In this review we describe isolation and asymmetric syntheses of several new alkaloids such as lycoposerramines-C, -V, -W, and cernuine, and show that asymmetric total synthesis played a key role in elucidating the structures of these complex natural products.
authors: Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
authors: Mariko
authors: M
authors: Kitajima
authors: Hiromitsu
authors: H
authors: Takayama
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000302:isolation & purification; D001688:Biological Products / Q000138:chemical synthesis* / Q000302:isolation & purification*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000302:isolation & purification; D032502:Lycopodium / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D010880:Piperidines / Q000138:chemical synthesis / Q000302:isolation & purification; D011804:Quinolines / Q000138:chemical synthesis / Q000302:isolation & purification; D054837:Quinolizidines / Q000138:chemical synthesis / Q000302:isolation & purification; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D001688:Biological Products; D006576:Heterocyclic Compounds, 4 or More Rings; D010880:Piperidines; D011804:Quinolines; D054837:Quinolizidines; C529946:cernuine; C524731:fawcettimine; C546484:lycoposerramine-C; C523753:lycoposerramine-V; C523754:lycoposerramine-W