title: [Study on industrialized extraction technology and function of hyperlipidemic regulating of Laminaria japonica polysaccharides].
abstract: OBJECTIVE
  To study the industrialized extraction technology and the function of hyperlipidemic regulating of Laminaria japonica polysaccharides.
  
  
  METHODS
  With the orthogonal design L9 (3(4)), different influential elements of the industrialized extraction technology of Laminaria japonica polysaccharides were investigated. Mice treated with different doses of polysaccharides were applied to investigate its-function of hyperlipidemic regulating for 15 days.
  
  
  RESULTS
  5% Na2CO3, 3 hours and 80 degrees C was the best extraction condition, and the extraction rate was 2.13%. Different groups of polysaccharides with different levels of purity and dose lowered the TG, TC level of the mice in various degree.
  
  
  CONCLUSIONS
  Laminaria japonica polysaccharides have obvious effect on hyperlipidemic regulating.
authors: The State Key Laboratory of Biocontrol and The Key Laboratory of Gene Engineering of Ministry of Education, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China. 2pactac2@163.com
authors: Ze-Zhi
authors: ZZ
authors: Yuan
authors: Kai-Ming
authors: KM
authors: Cheng
authors: Wen
authors: W
authors: Huang
authors: Dilshat
authors: Dong-Ru
authors: DR
authors: Feng
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D005260:Female; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D007795:Laminaria / Q000737:chemistry*; D008297:Male; D051379:Mice; D011134:Polysaccharides / Q000008:administration & dosage / Q000302:isolation & purification* / Q000494:pharmacology*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D004365:Drugs, Chinese Herbal; D000960:Hypolipidemic Agents; D011134:Polysaccharides; D014280:Triglycerides; D002784:Cholesterol