title: Analysis of telomere proteins by Chromatin Immunoprecipitation (ChIP).
abstract: Telomere Chromatin Immunoprecipitation (ChIP) is an experimental method used to determine whether proteins are associated with telomere DNA inside the nucleus of cells or tissues. Telomere-associated proteins are covalently cross-linked to telomere DNA, and then immunoprecipitated using a specific antibody for the protein. This method has become one of the most indispensable tools for unraveling the protein complexes that associate with the telomeres.
authors: Department of Biochemistry, State Key Laboratory of Biocontrol, College of Life Sciences, Sun Yat-sen University, Guangzhou, China. mawenbin@mail.sysu.edu.cn
authors: Wenbin
authors: W
authors: Ma
mesh_terms: D047369:Chromatin Immunoprecipitation / Q000379:methods*; D004247:DNA / Q000032:analysis / Q000235:genetics / Q000302:isolation & purification; D006367:HeLa Cells; D006801:Humans; D019098:Telomerase / Q000032:analysis / Q000235:genetics; D016615:Telomere / Q000378:metabolism*; D034501:Telomere-Binding Proteins / Q000032:analysis* / Q000235:genetics
chemical_list: D034501:Telomere-Binding Proteins; D004247:DNA; D019098:Telomerase