title: Weight gain--as possible predictor of metabolic syndrome.
abstract: Rapid weight gain among patients with mental disorders can further compound psychological distress and negatively influence compliance. Weight gain associated with treatment with atypical antipsychotic medication has been widely recognized as a risk factor for the development of diabetes type II and cardiovascular diseases. This paper describes a 33-year old female patient treated for schizoaffective disorder. Within two months after introducing quetiapine the patient experienced considerable weight gain amounting to 19 kg. The replacement of antipsychotic during inpatient psychiatric care resulted in weight loss.
authors: University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Cambierieva 17/7, 51000 Rijeka, Croatia. tanja.grahovac@ri.t-com.hr
authors: Tanja
authors: T
authors: Grahovac
authors: Klementina
authors: K
authors: Ružić
authors: Elizabeta
authors: E
authors: Dadić-Hero
authors: Dubravka
authors: D
authors: Sepić-Grahovac
authors: Vladimir
authors: V
authors: Sabljić
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015992:Body Mass Index; D003987:Dibenzothiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D024821:Metabolic Syndrome / Q000139:chemically induced* / Q000175:diagnosis*; D010343:Patient Admission; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000069348:Quetiapine Fumarate; D013844:Thiazoles / Q000009:adverse effects / Q000627:therapeutic use; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D010879:Piperazines; D013844:Thiazoles; D000069348:Quetiapine Fumarate; C092292:ziprasidone