title: The association between arterial stiffness and colorectal adenomatous polyp in women.
abstract: BACKGROUND
  Colorectal adenomatous polyp is a precancerous lesion, and some studies have documented its link with cardiovascular risk factors. This study aimed to investigate the association between arterial stiffness and colorectal adenomatous polyp.
  
  
  METHODS
  Among 388 Korean women, we examined the association between brachial-ankle pulse wave velocity (baPWV) as a measurement of arterial stiffness and the presence of colorectal adenomatous polyp as determined by colonoscopy. baPWV values were categorized separately as follows: ≤1199 cm/s, 1200-1399 cm/s, 1400-1599 cm/s and ≥1600 cm/s. The odds ratios (ORs) and 95% confidence intervals (CIs) for colorectal adenomatous polyp were calculated across each group of PWVs.
  
  
  RESULTS
  The prevalence of colorectal adenomatous polyp was 9.5%. After adjusting for age, body mass index (BMI), cigarette smoking, blood pressure, fasting plasma glucose, and triglycerides, the ORs (95% CIs) for colorectal adenomatous polyp according to each of the four groups of baPWV were 1.00, 2.89 (0.52-15.98), 3.27 (0.48-22.24), and 11.17 (1.17-106.99).
  
  
  CONCLUSIONS
  A higher level of baPWV was found to be independently associated with the presence of colorectal adenomatous polyp, regardless of classic cardiovascular risk factors and other components of metabolic syndrome in women.
authors: Department of Family Medicine, Yonsei University College of Medicine, Yongin-city, Gyeonggi-do, Korea.
authors: Hong-Bae
authors: HB
authors: Kim
authors: Hye-Ree
authors: HR
authors: Lee
authors: Jae-Yong
authors: JY
authors: Shim
authors: Ha-young
authors: HY
authors: Na
authors: Byoung-Jin
authors: BJ
authors: Park
authors: Dong-Hyuk
authors: DH
authors: Jung
authors: Yong-Jae
authors: YJ
authors: Lee
mesh_terms: D018256:Adenomatous Polyps / Q000150:complications* / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D050197:Atherosclerosis / Q000150:complications* / Q000453:epidemiology*; D001916:Brachial Artery / Q000502:physiology; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000150:complications* / Q000453:epidemiology* / Q000473:pathology; D003430:Cross-Sectional Studies; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult