title: The association of smoking and erectile dysfunction: results from the Fangchenggang Area Male Health and Examination Survey (FAMHES).
abstract: To describe the prevalence of erectile dysfunction (ED) and its association  with smoking and other risk factors among a large male population. Data were  collected from 2686 men attending the Fangchenggang Area Male Health and  Examination Survey from September 2009 to December 2009. ED was assessed using  the 5-item International Index of Erectile Function. Self-reported smoking  history was obtained from the questionnaire. Prevalence of ED was 49.5% among  2686 Chinese men in Fangchenggang aged 20-79 years. After adjusting for  age, alcohol drinking, physical activity, hypertension, diabetes,  dyslipidemia, and obesity, smokers who smoked ≥20 cigarettes daily had a  significantly increased risk of ED than never smokers (odds ratio [OR], 1.23;  95% confidence interval [CI], 1.03-1.49; P = .02). After  further adjustment for education, the risk of ED was still significantly  higher in men smoking more than 23 years than never smokers (OR, 1.60; 95% CI,  1.22-2.09; P = .001). Association of age and education with ED  was statistically significant after adjusting for the other variables. A  history of diabetes and hypertension all increased the risk of ED, but  statistically significant differences did not exist after adjustment for other  variables. The association between smoking and ED risk in men was higher with  a habit of drinking alcohol (OR, 1.32; 95% CI, 1.01-1.74) or physical  inactivity (OR, 1.33; 95% CI, 1.05-1.67), or with a with a history of  hypertension (OR, 1.71; 95% CI, 1.11-2.62), dyslipidemia (OR, 1.39; 95%  CI, 1.06-1.81), and diabetes (OR, 2.69; 95% CI, 1.4-6.98). Our  results show that heavy smoking might cause ED and that the duration of the  habit increases the risk of ED. Furthermore, it highlights the potential  interaction of smoking with other life habits or medical history on ED  risk.
authors: Institute of Urology and Nephrology, First Affiliated Hospital, Guangxi Medical University, 22 Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, China.
authors: Chunlei
authors: C
authors: Wu
authors: Haiying
authors: H
authors: Zhang
authors: Yong
authors: Y
authors: Gao
authors: Aihua
authors: A
authors: Tan
authors: Xiaobo
authors: X
authors: Yang
authors: Zheng
authors: Z
authors: Lu
authors: Youjie
authors: Y
authors: Zhang
authors: Ming
authors: M
authors: Liao
authors: Mengjie
authors: M
authors: Wang
authors: Zengnan
authors: Z
authors: Mo
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008297:Male; D015995:Prevalence; D012907:Smoking / Q000009:adverse effects*; D011795:Surveys and Questionnaires