title: Acute exercise improves endothelial function despite increasing vascular resistance during stress in smokers and nonsmokers.
abstract: The present study examined the effect of acute exercise on flow mediated dilation (FMD) and reactivity to neurovascular challenges among female smokers and nonsmokers. FMD was determined by arterial diameter, velocity, and blood flow measured by Doppler ultrasonography after forearm occlusion. Those measures and blood pressure and heart rate were also assessed in response to forehead cold and the Stroop Color-Word Conflict Test (CWT) before and after 30 min of rest or an acute bout of cycling exercise (∼50% VO₂ peak). Baseline FMD and stress responses were not different between smokers and nonsmokers. Compared to passive rest, exercise increased FMD and decreased arterial velocity and blood flow responses during the Stroop CWT and forehead cold in both groups. Overall, acute exercise improved endothelial function among smokers and nonsmokers despite increasing vascular resistance and reducing limb blood flow during neurovascular stress.
authors: Department of Kinesiology, University of Georgia, Athens, Georgia 30322, USA. cherie.rooks@emory.edu
authors: Cherie R
authors: CR
authors: Rooks
authors: Kevin K
authors: KK
authors: McCully
authors: Rod K
authors: RK
authors: Dishman
mesh_terms: D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000502:physiology; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D005542:Forearm / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D012039:Regional Blood Flow / Q000502:physiology; D012907:Smoking / Q000503:physiopathology*; D013312:Stress, Physiological / Q000502:physiology*; D014463:Ultrasonography; D014655:Vascular Resistance / Q000502:physiology*; D014664:Vasodilation / Q000502:physiology