title: Dendritic cells as a tool to induce transplantation tolerance: obstacles and opportunities.
abstract: Dendritic cells are the key component to regulate and coordinate adaptive immune responses, including tolerance. This overview will briefly summarize different strategies to generate tolerogenic dendritic cell and the in vivo use of these cells in experimental transplantation models. We discuss some obstacles and possible solutions including alternative strategies for the use of negative vaccination in the context of organ transplantation.
authors: Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands. kooten@lumc.nl
authors: Cees
authors: C
authors: van Kooten
authors: Giovanna
authors: G
authors: Lombardi
authors: Kyra A
authors: KA
authors: Gelderman
authors: Pervinder
authors: P
authors: Sagoo
authors: Matthew
authors: M
authors: Buckland
authors: Robert
authors: R
authors: Lechler
authors: Maria Cristina
authors: MC
authors: Cuturi
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000276:immunology* / Q000637:transplantation*; D006801:Humans; D007108:Immune Tolerance; D051379:Mice; D016377:Organ Transplantation; D051381:Rats; D014181:Transplantation Immunology