title: Genetic testing for hereditary cancer: effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure.
abstract: This study assessed the impact of the results of genetic testing for hereditary cancer from a multifactorial health psychology perspective, considering that emotional expression plays a key role in psychological adjustment. Measures of dispositional and transactional coping strategies, anxiety and alexithymia were filled out by 77 participants in a longitudinal study design. Statistical analyses were performed using general linear models and partial least squares path modelling, low-constraint methods that are particularly useful in the behavioural sciences. While anxiety levels prior to the result announcement were predictive of the distress experienced by noncarriers, considerable variability was observed for mutation carriers. Some subjects who had lower anxiety levels before the test displayed greater anxiety afterwards, but others seemed to anticipate the distress they would experience with the result that they showed a decrease in anxiety. The mutation carriers behaved as though their adaptive functioning were reshaped by the test result, independent of their disposition and previous emotional state, except in the case of alexithymia. Difficulty expressing emotions prior to genetic testing contributed to a similar difficulty after receiving the result, adding to the latter's emotional impact by promoting emotion-focused coping strategies and increasing distress.
authors: Center for Research in Psychology of Cognition, Language and Emotion, Aix Marseille I University, France. carole.fantini@univ-provence.fr
authors: Carole
authors: C
authors: Fantini-Hauwel
authors: Bruno
authors: B
authors: Dauvier
authors: Thomas
authors: T
authors: Arciszewski
authors: Pascal
authors: P
authors: Antoine
authors: Sylvie
authors: S
authors: Manouvrier
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000342:Affective Symptoms; D001007:Anxiety; D030881:Disclosure; D005260:Female; D005602:France; D005820:Genetic Testing; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000235:genetics*; D011795:Surveys and Questionnaires