title: [Evaluation of topical vasoconstrictors in pterygium surgery and their role in reducing intraoperative bleeding].
abstract: OBJECTIVE
  To reduce vascularisation before surgery through the application of topical vasoconstrictors, decreases the rate of intraoperative bleeding, improves the dynamics of the surgery and reduces the difficulty in surgical performance.
  
  
  METHODS
  Only patients with primary pterygium were included in the study. A prospective randomized clinical trial was designed to compare intraoperative bleeding, need for cauterization and surgical time a group that was administered phenylephrine. preoperatively and one which did not receive it. The sample was divided into two groups: 1st (n=27) received topical phenylephrine (F) 0.1 ml (10%), twice in 5 minutes before surgery. 2nd (n=30) did not receive phenylephrine (NoF). The technique was similar in both groups using conjunctival autograft suturing. In both groups, the subconjunctival aneasthesia was performed with 0.5% bupivacaine hydrochloride with epinephrine 1:200,000.
  
  
  RESULTS
  A total of 57 patients were included in the study. The mean operation time for group F was 15.57 minutes (SD: 1.8 min) and the NoF group 16.51 min (SD to 1.82 min, P=.057). In the group F, it was necessary to use diathermy in 2 patients (7.4%) and in the NoF group cauterisation was used in 14 patients (46.7%, Chi-Square=10.848, P=.001. There is a relative risk 6.3 (95% CI 1.57 - 25.27) times greater than having to cauterise without phenylephrine when used phenylephrine.
  
  
  CONCLUSIONS
  The use of topical vasconstrictors prior to pterygium surgery reduces the rate of bleeding and the time of surgery.
authors: Clínica de Oftalmología MASER, Córdoba, España. drvill@terra.es
authors: E
authors: E
authors: Villegas Becerril
authors: L
authors: L
authors: Pérula de Torres
authors: M
authors: M
authors: Bergillos Arillo
authors: C
authors: C
authors: Villegas del Cuvillo
mesh_terms: D000759:Adjuvants, Anesthesia; D000287:Administration, Topical; D000779:Anesthetics, Local; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002045:Bupivacaine; D003228:Conjunctiva / Q000637:transplantation; D004564:Electrocoagulation / Q000706:statistics & numerical data; D004837:Epinephrine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010656:Phenylephrine / Q000008:administration & dosage / Q000627:therapeutic use*; D011229:Preanesthetic Medication; D011446:Prospective Studies; D011625:Pterygium / Q000601:surgery*; D012306:Risk; D013536:Suture Techniques; D013997:Time Factors; D014182:Transplantation, Autologous; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000759:Adjuvants, Anesthesia; D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D010656:Phenylephrine; D002045:Bupivacaine; D004837:Epinephrine