title: SPION nanoparticles as an efficient probe and carrier of DNA to umbilical cord blood-derived mesenchymal stem cells.
abstract: Superparamagnetic iron oxide nanoparticles (SPION) were used to transfer gene into umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) in this study. This novel transfection method using SPION is safe and effective to UCB-MSCs, and would be a tool for genetic optimization with a significant potential for cell tracing.
authors: Heart Research Center, Chonnam National University Hospital, Gwangju 501-757, South Korea.
authors: Yong Sook
authors: YS
authors: Kim
authors: In-Kyu
authors: IK
authors: Park
authors: Won Jong
authors: WJ
authors: Kim
authors: Mi Kyung
authors: MK
authors: Yu
authors: Sangyoung
authors: S
authors: Jon
authors: Suzie H
authors: SH
authors: Pun
authors: Myung Ho
authors: MH
authors: Jeong
authors: Youngkeun
authors: Y
authors: Ahn
mesh_terms: D005312:Fetal Blood / Q000166:cytology; D018014:Gene Transfer Techniques; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D058185:Magnetite Nanoparticles; D059630:Mesenchymal Stem Cells / Q000166:cytology; D036103:Nanotechnology; D010957:Plasmids / Q000008:administration & dosage* / Q000235:genetics*; D014162:Transfection
chemical_list: D058185:Magnetite Nanoparticles