title: Nosocomial dissemination of extended-spectrum β-lactamase VEB-1a-producing Providencia stuartii isolates in a Tunisian hospital.
abstract: A collection of 20 multidrug-resistant Providencia stuartii isolates recovered from 2005 to 2009 at the Military Hospital of Tunis, Tunisia, was analysed. They all expressed the extended-spectrum β-lactamase (ESBL) VEB-1a. The bla (VEB-1a) gene was plasmid-located and it was associated with complex genetic structures, including Re elements. Pulsed-field gel electrophoresis (PFGE) revealed a clonal relationship between all of these isolates. This study identified a nosocomial dissemination of an ESBL-producing P. stuartii clone in a Tunisian hospital over a long period of time.
authors: Laboratoire de Biochimie et de Technobiologie, Faculté des Sciences de Tunis, Campus Universitaire, 2092 El-Manar II, Tunisia.
authors: H
authors: H
authors: Lahlaoui
authors: L
authors: L
authors: Poirel
authors: M B
authors: MB
authors: Moussa
authors: M
authors: M
authors: Ferjani
authors: B
authors: B
authors: Omrane
authors: P
authors: P
authors: Nordmann
mesh_terms: D000328:Adult; D000368:Aged; D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D029968:Escherichia coli Proteins; D005260:Female; D005798:Genes, Bacterial; D005838:Genotype; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D010957:Plasmids; D011532:Providencia / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D014416:Tunisia / Q000453:epidemiology; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D029968:Escherichia coli Proteins; C119424:beta-lactamase VEB-1, E coli; D001618:beta-Lactamases