title: Telomere strand-specific length analysis by fluorescent in situ hybridization (Q-CO-FISH).
abstract: The implementation of quantitative approaches in telomere chromosome-oriented FISH (telomeric CO-FISH) allows the assessment of the relative efficiency of lagging versus leading strand telomere replication and thus provides information on the implicated mechanisms. Here, we describe a simple method for telomere strand-specific analyses and discuss its potential applications.
authors: Telomeres & Cancer Laboratory, Institut Curie, Paris, France.
authors: Isabelle
authors: I
authors: Ourliac-Garnier
authors: Arturo
authors: A
authors: Londoño-Vallejo
mesh_terms: D002478:Cells, Cultured; D004261:DNA Replication; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D016615:Telomere / Q000737:chemistry* / Q000378:metabolism