title: Gerosuppressant metformin: less is more.
authors.affiliation: Catalan Institute of Oncology, Girona, Catalonia, Spain. jmenendez@iconcologia.net
authors.forename: Javier A
authors.initials: JA
authors.lastname: Menendez
authors.forename: Sílvia
authors.initials: S
authors.lastname: Cufí
authors.forename: Cristina
authors.initials: C
authors.lastname: Oliveras-Ferraros
authors.forename: Luciano
authors.initials: L
authors.lastname: Vellon
authors.forename: Jorge
authors.initials: J
authors.lastname: Joven
authors.forename: Alejandro
authors.initials: A
authors.lastname: Vazquez-Martin
mesh_terms: D000263:Adenylate Kinase / Q000378:metabolism; D000375:Aging / Q000187:drug effects*; D000818:Animals; D001943:Breast Neoplasms / Q000235:genetics / Q000503:physiopathology; D016922:Cellular Senescence / Q000187:drug effects / Q000502:physiology; D018450:Disease Progression; D004791:Enzyme Inhibitors / Q000494:pharmacology; D058750:Epithelial-Mesenchymal Transition; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008017:Life Expectancy; D008136:Longevity / Q000187:drug effects*; D008687:Metformin / Q000494:pharmacology*; D051379:Mice; D019893:Ribosomal Protein S6 Kinases / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D007004:Hypoglycemic Agents; D008687:Metformin; D019893:Ribosomal Protein S6 Kinases; D058570:TOR Serine-Threonine Kinases; D000263:Adenylate Kinase