title: [Role of statins in patients with acute coronary syndromes].
abstract: After 10 years of studies on statins in acute coronary syndromes what have we learned? (1) The use of statins in acute coronary syndromes reduces coronary events during follow-up; (2) an "intensive" strategy based on the use of potent high dosage statins is effective on 4 to 6 months prognosis, nevertheless side effects and drug withdrawal are frequent; (3) beyond the usual paradigm "the lower the better", the new paradigm of "long term sustainability" should be developed, adopting adequate strategies; (4) a target-oriented study on statins in acute coronary syndrome is desirable, to evaluate which LDL values should be achieved or maintained for the best prognostic benefit.
authors.affiliation: U.O.C. di Cardiologia, Ospedale Bellaria, Bologna. stefano.urbinati@ausl.bo.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Urbinati
authors.forename: Graziana
authors.initials: G
authors.lastname: Labanti
authors.forename: Simona
authors.initials: S
authors.lastname: Gambetti
mesh_terms: D054058:Acute Coronary Syndrome / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors