title: Mycoplasma genitalium infection among HIV-positive women: prevalence, risk factors and association with vaginal shedding.
abstract: This study examined the prevalence and factors associated with Mycoplasma genitalium (MG) infection among HIV-positive women and the association between MG and vaginal HIV-1 RNA shedding. HIV-positive women attending an outpatient clinic in New Orleans, Louisiana, USA, from 2002 to 2005 were examined for a battery of sexually transmitted infections (STIs) and underwent a behavioural survey. A selected subset had a measurement of vaginal shedding analysed. Of the 324 HIV-positive women, 32 (9.9%) were infected with MG. HIV-positive women with MG were more likely to be co-infected with Neisseria gonorrhoeae and Chlamydia trachomatis and to have had ≥1 male sexual partners in the last month. In the subset (n = 164), no differences were found in the presence of detectable vaginal HIV-1 RNA between women infected and not infected with MG (30.8% versus 34.8% shedding; P = 0.69). While MG was a common co-STI in this sample of HIV-positive women, it was not associated with vaginal HIV shedding.
authors.affiliation: Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, LA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Gatski
authors.forename: D H
authors.initials: DH
authors.lastname: Martin
authors.forename: K
authors.initials: K
authors.lastname: Theall
authors.forename: A
authors.initials: A
authors.lastname: Amedee
authors.forename: R A
authors.initials: RA
authors.lastname: Clark
authors.forename: J
authors.initials: J
authors.lastname: Dumestre
authors.forename: P
authors.initials: P
authors.lastname: Chhabra
authors.forename: N
authors.initials: N
authors.lastname: Schmidt
authors.forename: P
authors.initials: P
authors.lastname: Kissinger
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006678:HIV / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology; D006801:Humans; D016015:Logistic Models; D008145:Louisiana / Q000453:epidemiology; D008875:Middle Aged; D015999:Multivariate Analysis; D009175:Mycoplasma Infections / Q000453:epidemiology / Q000821:virology*; D045704:Mycoplasma genitalium / Q000302:isolation & purification*; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D012307:Risk Factors; D012959:Socioeconomic Factors; D014621:Vagina / Q000821:virology*; D017201:Virus Shedding
chemical_list: D012367:RNA, Viral