title: Prevalence of thyroid dysfunction in patients with type 2 diabetes.
abstract: OBJECTIVE
  Assess the prevalence of thyroid dysfunction in patients with type 2 diabetes (T2D) in Segovia (Spain).
  
  
  METHODS
  A screening program for thyroid dysfunction including all patients with T2D attending the diabetes clinic at the Hospital General de Segovia was performed from 2003 to 2005.
  
  
  RESULTS
  318 patients (191 women, aged 29-89 yr, median duration of diabetes 8 yr) attended the diabetes clinic. The number of patients with thyroid dysfunction and their respective prevalences were: overt hyperthyroidism, 11 (3.5%); subclinical hyperthyroidism, 10 (3.1%); overt hypothyroidism, 48 (15.1%), and subclinical hypothyroidism, 34 patients (10.7%). The screening program detected the following cases of newly diagnosed thyroid dysfunction: subclinical hyperthyroidism, 5 (1.6%); overt hypothyroidism, 6 (1.9%), and subclinical hypothyroidism, 20 patients (6.3%). Therefore, total thyroid dysfunction was present in 32.4% (95% CI, 27.3-37.5%), and newly diagnosed thyroid dysfunction was present 9.7% (95% CI, 6.5-13.0%) of the patients. Logistic regression analysis showed that there were no significant relationships between the presence of thyroid dysfunction and duration of diabetes, hemoglobin A1c levels, and the presence of diabetic complications.
  
  
  CONCLUSIONS
  This screening program detected new cases of thyroid dysfunction in ∼10% of diabetic subjects. However, we could not identify any diabetes-related clinical parameter with predictive value on the presence of thyroid dysfunction.
authors.affiliation: Department of Endocrinology, Hospital Ramón y Cajal, Madrid, Spain. jdiez.hrc@salud.madrid.org
authors.forename: J J
authors.initials: JJ
authors.lastname: Díez
authors.forename: P
authors.initials: P
authors.lastname: Sánchez
authors.forename: P
authors.initials: P
authors.lastname: Iglesias
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000097:blood / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D013959:Thyroid Diseases / Q000097:blood / Q000453:epidemiology* / Q000209:etiology
chemical_list: D006442:Glycated Hemoglobin