title: Bioinspired terpene synthesis: a radical approach.
abstract: This tutorial review highlights the development of radical-based bioinspired synthesis of terpenes from the initial proposal to the development of modern catalytic methods for performing such processes. The power of the radical approach is demonstrated by the straightforward syntheses of many natural products from readily available starting materials. The efficiency of these processes nicely complements the described cationic polyolefin cyclisations and even suggests that modern radical methods provide means to improve upon nature's synthetic pathways.
authors.affiliation: Department of Organic Chemistry, University of Granada, Campus Fuentenueva s/n, E-18071 Granada, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Justicia
authors.forename: Luis
authors.initials: L
authors.lastname: Álvarez de Cienfuegos
authors.forename: Araceli G
authors.initials: AG
authors.lastname: Campaña
authors.forename: Delia
authors.initials: D
authors.lastname: Miguel
authors.forename: Verena
authors.initials: V
authors.lastname: Jakoby
authors.forename: Andreas
authors.initials: A
authors.lastname: Gansäuer
authors.forename: Juan M
authors.initials: JM
authors.lastname: Cuerva
mesh_terms: D032701:Biomimetics / Q000379:methods*; D003500:Cyclization; D005609:Free Radicals / Q000737:chemistry*; D006801:Humans; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005609:Free Radicals; D013729:Terpenes