title: [Subclinical acute intermittent porphyria. An uncommon cause of chronic hepatitis].
abstract: Acute porphyria is a term that encompasses a group of hereditary disorders involving defects in heme metabolism, characterized by acute episodes of abdominal pain, acute hypertension, tachycardia and neuropsychiatric disorders, sometimes leading to convulsions, ascending paralysis and coma. Misdiagnosis or delayed diagnosis can seriously worsen prognosis. We report the case of a woman with subclinical acute intermittent porphyria and chronic hepatitis incidentally diagnosed due to transaminase elevation on laboratory analysis.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Universitario Virgen Macarena, Sevilla, España.
authors.forename: Juan
authors.initials: J
authors.lastname: Pérez Martínez
authors.forename: Cristina
authors.initials: C
authors.lastname: Castro Márquez
authors.forename: Sofía
authors.initials: S
authors.lastname: Pereira Gallardo
authors.forename: Manuel
authors.initials: M
authors.lastname: Jiménez Sáenz
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Herrerías Gutiérrez
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001706:Biopsy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005799:Genes, Dominant; D006505:Hepatitis / Q000097:blood / Q000209:etiology* / Q000473:pathology; D019693:Hepatitis, Autoimmune / Q000175:diagnosis; D006801:Humans; D011163:Hydroxymethylbilane Synthase / Q000097:blood; D033162:Incidental Findings; D019683:Penetrance; D017118:Porphyria, Acute Intermittent / Q000150:complications / Q000175:diagnosis / Q000235:genetics / Q000378:metabolism
chemical_list: D011163:Hydroxymethylbilane Synthase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase