title: Diversity-oriented approach to 1,2-dihydroisoquinolin-3(4H)-imines via copper(I)-catalyzed reaction of (E)-2-ethynylphenylchalcone, sulfonyl azide and amine.
abstract: A three-component reaction of (E)-2-ethynylphenylchalcone, sulfonyl azide, and amine catalyzed by copper(I) chloride (5 mol%), in the presence of triethylamine, under mild conditions is described. This transformation proceeds efficiently to generate 1,2-dihydroisoquinolin-3(4H)-imines in good to excellent yields.
authors.affiliation: Key Laboratory of Functional Small Organic Molecules, Ministry of Education and College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, China.
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Chen
authors.forename: Chao
authors.initials: C
authors.lastname: Ye
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000588:Amines / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D047188:Chalcones / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D007546:Isoquinolines / Q000737:chemistry*
chemical_list: D000588:Amines; D001386:Azides; D047188:Chalcones; D007546:Isoquinolines; D003300:Copper