title: Studies on the supramolecular interaction between dimethomorph and disulfide linked β-cyclodextrin dimer by spectrofluorimetry and its analytical application.
abstract: The supramolecular interaction of disulfide linked β-cyclodextrin (β-CD) dimer and dimethomorph has been studied by spectrofluorimetry. Based on the significant enhancement of the fluorescence intensity of dimethomorph, a new spectrofluorimetric method with high sensitivity and selectivity was developed for the determination of dimethomorph in bulk aqueous in the presence of the disulfide linked β-CD dimer. The inclusion complexation behavior of β-CD dimer with dimethomorph was studied in a KH(2)PO(4)-H(3)PO(4) buffer solution of pH 3.86 at room temperature. The apparent association constant of the complex was 2.25 × 10(4) L/mol. The linear range was 12-7500 ng/mL with the detection limit 3.70 ng/mL, and the limit of quantification was 12.4 ng/mL. The proposed method had been successfully applied to the determination of dimethomorph residues in vegetables with recoveries of 89.0-115%.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Shandong Normal University, Jinan, P R China.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Chen
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Chen
authors.forename: Kehua
authors.initials: K
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D019281:Dimerization; D004220:Disulfides / Q000737:chemistry*; D004347:Drug Interactions; D005453:Fluorescence; D005470:Fluorometry / Q000379:methods*; D015394:Molecular Structure; D009025:Morpholines / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D004220:Disulfides; D009025:Morpholines; D047392:beta-Cyclodextrins; C076154:dimethomorph