title: Cell membrane-associated mineralocorticoid receptors? New evidence.
abstract: The purpose of the present article is to provide an overview of plasma membrane steroid hormone receptors and their implications in nongenomic signaling. We especially focus on recent evidence supporting the notion of a possible membrane-associated aldosterone receptor, whether this receptor is different from the classic nuclear receptor, and the possible implications of such a receptor for nongenomic and genomic aldosterone effects in physiological and pathophysiological processes.
authors.affiliation: Brigham and Women's Hospital/Harvard Medical School, Division of Endocrinology, Diabetes, and Hypertension, 221 Longwood Ave, Boston, MA 02115, USA.
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Krug
authors.forename: Luminita H
authors.initials: LH
authors.lastname: Pojoga
authors.forename: Gordon H
authors.initials: GH
authors.lastname: Williams
authors.forename: Gail K
authors.initials: GK
authors.lastname: Adler
mesh_terms: D000450:Aldosterone / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D066246:ErbB Receptors / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000378:metabolism*; D018161:Receptors, Mineralocorticoid / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D011956:Receptors, Cell Surface; D018161:Receptors, Mineralocorticoid; D000450:Aldosterone; D066246:ErbB Receptors