title: Postoperative renal function in patients is unaltered after robotic-assisted radical prostatectomy.
abstract: BACKGROUND
  Pneumoperitoneum with an intra-abdominal pressure (IAP) of 14 mmHg is known to decrease renal function. Robotic-assisted radical prostatectomy (RARP) requires an IAP of more than 15 mmHg for operation. Therefore, we retrospectively investigated whether patients who underwent RARP experienced renal insufficiency during the postoperative period (at postoperative days 7 and 30).
  
  
  METHODS
  One hundred patients who underwent RARP were enrolled in this study. Preoperative serum blood urea nitrogen (BUN) and serum creatinine (Cr) levels were measured. Creatinine clearance (CrCl) was calculated using the Cockcroft and Gault formula. CrCl was calculated at 1 day before surgery (baseline), 2 hr postoperatively, and at 1, 3, 7, and 30 days postoperatively (POD 1, POD 3, POP 7, and POD 30). Patients were assigned to abnormal CrCl (n = 52) or normal CrCl groups (n = 48) on the basis of these measurements.
  
  
  RESULTS
  Significant inter-group differences in BUN, Cr, and CrCl were observed at all postoperative time points. BUN and Cr decreased significantly at postoperative 2 hr and POD 1, 3, and 7 versus baseline in both groups, whereas CrCl increased significantly at postoperative 2 hr and POD 1, 3, and 7 versus baseline in both groups. However, BUN, Cr, and CrCl were similar at POD 30 and preoperatively in the two groups.
  
  
  CONCLUSIONS
  RAPR, which requires an IAP of 15-20 mmHg for more than 4 hr, does not induce renal dysfunction during the postoperative period, and even in those patients with an abnormal CrCl.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Ahn
authors.forename: Choon Hak
authors.initials: CH
authors.lastname: Lim
authors.forename: Hye In
authors.initials: HI
authors.lastname: Chung
authors.forename: Seong Uk
authors.initials: SU
authors.lastname: Choi
authors.forename: Seung Zoo
authors.initials: SZ
authors.lastname: Youn
authors.forename: Hae Ja
authors.initials: HJ
authors.lastname: Lim