title: Follicular dominance on the fifth day of controlled ovarian stimulation reduces implantation in long down-regulated ICSI cycles.
abstract: OBJECTIVE
  To determine if follicular dominance on the fifth day of controlled ovarian stimulation (COS) predicts implantation rates in down-regulated intracytoplasmic sperm injection (ICSI) cycles.
  
  
  METHODS
  One hundred and sixty-two consecutive women undergoing ICSI treatment with long down-regulation and recombinant follicle-stimulating hormone injections were included in a prospective cohort analysis. The clinical pregnancy and implantation rates per transfer were compared between two groups, one with and the other without follicular dominance detected by ultrasound on the fifth day of COS.
  
  
  RESULTS
  There was no significant difference between the groups regarding the number of good quality embryos transferred, but clinical pregnancy and implantation rate per transfer were higher in group with follicular synchrony.
  
  
  CONCLUSIONS
  Follicular dominance on COS day 5 results in reduced implantation rates after ICSI.
authors.affiliation: Marmara University, School of Medicine, Department of Obstetrics and Gynecology, Istanbul, Turkey. tevfik.yoldemir@gmail.com
authors.forename: Tevfik
authors.initials: T
authors.lastname: Yoldemir
authors.forename: Mithat
authors.initials: M
authors.lastname: Erenus
authors.forename: Fatih
authors.initials: F
authors.lastname: Durmusoglu
mesh_terms: D000328:Adult; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D006080:Ovarian Follicle / Q000187:drug effects; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors; D055815:Young Adult