title: Coronary thrombosis and myocardial infarction as the initial manifestation of protein C deficiency in a 20-year-old man.
abstract: We report on a 20-year-old man who presented with an extensive acute anteroseptal myocardial infarction (from a thrombotic occlusion of the left anterior coronary artery) as the initial manifestation of hereditary protein C deficiency. This case report, along with previous reports, indicates that a diagnosis of protein C deficiency in young patients with myocardial infarctions is essential for more appropriate management and for the prevention of recurrent events. Furthermore, family screening could lead to a prophylactic approach in carriers of this mutation.
authors.affiliation: Cardiovascular Department, Pars General Hospital, Tehran, Iran.
authors.forename: Parham
authors.initials: P
authors.lastname: Eshtehardi
authors.forename: Parisa
authors.initials: P
authors.lastname: Ghassemi-Kakroodi
authors.forename: Ali
authors.initials: A
authors.lastname: Garachemani
authors.forename: Masoud
authors.initials: M
authors.lastname: Eslami
authors.forename: Davood Akhlagh
authors.initials: DA
authors.lastname: Moayed
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D000077144:Clopidogrel; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D020151:Protein C Deficiency / Q000150:complications* / Q000175:diagnosis; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D013997:Time Factors; D014859:Warfarin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D014859:Warfarin; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin