title: Hepatitis a virus vaccine escape variants and potential new serotype emergence.
abstract: Six hepatitis A virus antigenic variants that likely escaped the protective effect of available vaccines were isolated, mostly from men who have sex with men. The need to complete the proper vaccination schedules is critical, particularly in the immunocompromised population, to prevent the emergence of vaccine-escaping variants.
authors.affiliation: University of Barcelona, Barcelona, Spain.
authors.forename: Unai
authors.initials: U
authors.lastname: Pérez-Sautu
authors.forename: M Isabel
authors.initials: MI
authors.lastname: Costafreda
authors.forename: Joan
authors.initials: J
authors.lastname: Caylà
authors.forename: Cecilia
authors.initials: C
authors.lastname: Tortajada
authors.forename: Josep
authors.initials: J
authors.lastname: Lite
authors.forename: Albert
authors.initials: A
authors.lastname: Bosch
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Pintó
mesh_terms: D019943:Amino Acid Substitution; D000940:Antigenic Variation / Q000276:immunology; D006506:Hepatitis A / Q000145:classification / Q000821:virology*; D022362:Hepatitis A Vaccines; D030041:Hepatitis A virus / Q000235:genetics* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology; D008297:Male; D009154:Mutation / Q000235:genetics; D010802:Phylogeny; D014611:Vaccination; D015678:Viral Structural Proteins / Q000235:genetics
chemical_list: D022362:Hepatitis A Vaccines; C096539:VP1 protein, hepatitis A virus; D015678:Viral Structural Proteins