title: Correlation between Dermatology Life Quality Index and Minor test and differences in their levels over time in patients with axillary hyperhidrosis treated with botulinum toxin type A.
abstract: Hyperhidrosis is an idiopathic condition of exaggerated sweat production resulting in dramatic impairments of daily activities, social interactions and occupational activities. The aim of the present study was to evaluate correlation between a subjective (Dermatology Life Quality Index) and an objective (Minor test) criterion and to assess difference in their levels over time in patients affected by axillary hyperhidrosis treated with botulinum toxin type A. Nineteen patients received injections of 50 U of botulinum toxin type A per axilla. Patients were observed for 9 months after treatment. All patients showed great improvement of hyperhidrosis by Minor test and Dermatology Life Quality Index following treatment with botulinum toxin type A, with the effect persisting for 6-9 months. All patients demonstrated direct relationship between objective improvement documented by Minor test and quality of live improvement documented by Dermatology Life Quality Index after treatment with botulinum toxin type A.
authors.affiliation: UOC of Dermatology "Daniele Innocenzi" Sapienza University of Rome, Polo Pontino, Italy. nevena.skroza@uniroma1.it
authors.forename: Nevena
authors.initials: N
authors.lastname: Skroza
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Bernardini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: La Torre
authors.forename: Giorgio
authors.initials: G
authors.lastname: La Viola
authors.forename: Concetta
authors.initials: C
authors.lastname: Potenza
mesh_terms: D000328:Adult; D001365:Axilla; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000473:pathology / Q000523:psychology; D007150:Immunohistochemistry; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D016896:Treatment Outcome
chemical_list: D019274:Botulinum Toxins, Type A