title: Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.
authors.affiliation: TU Dortmund University, Faculty of Chemistry, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
authors.forename: Lea
authors.initials: L
authors.lastname: Radtke
authors.forename: Matthieu
authors.initials: M
authors.lastname: Willot
authors.forename: Hongyan
authors.initials: H
authors.lastname: Sun
authors.forename: Slava
authors.initials: S
authors.lastname: Ziegler
authors.forename: Stephanie
authors.initials: S
authors.lastname: Sauerland
authors.forename: Carsten
authors.initials: C
authors.lastname: Strohmann
authors.forename: Roland
authors.initials: R
authors.lastname: Fröhlich
authors.forename: Peter
authors.initials: P
authors.lastname: Habenberger
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
authors.forename: Mathias
authors.initials: M
authors.lastname: Christmann
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D006801:Humans; D020128:Inhibitory Concentration 50; D007680:Kidney Neoplasms / Q000473:pathology; D015394:Molecular Structure; D045789:Sesquiterpenes, Guaiane / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D045789:Sesquiterpenes, Guaiane; C534971:englerin A; C551614:englerin B