title: Industrial production of fructooligosaccharides by immobilized cells of Aureobasidium pullulans in a packed bed reactor.
abstract: Continuous production of fructooligosaccharides (FOS) by Aureobasidium pullulans immobilized on calcium alginate beads with a packed bed was investigated at a plant scale reactor. Optimum conditions were with 770 g sucrose/l, being fed at 200 l/h at 50°C which gave a productivity of 180 g FOS/l h. Initial activity was maintained for more than 100 days. The reactor was successfully scaled up to a production scale of 1.2 m(3).
authors.affiliation: Technical Center for Bio-Business Unit, CJ Cheiljedang Corporation, 92 Kayang-Dong, Kangseo-Ku, Seoul, Korea.
authors.forename: K H
authors.initials: KH
authors.lastname: Jung
authors.forename: S H
authors.initials: SH
authors.lastname: Bang
authors.forename: T K
authors.initials: TK
authors.lastname: Oh
authors.forename: H J
authors.initials: HJ
authors.lastname: Park
mesh_terms: D001203:Ascomycota / Q000201:enzymology / Q000378:metabolism*; D019149:Bioreactors / Q000382:microbiology*; D018914:Cells, Immobilized / Q000201:enzymology / Q000378:metabolism*; D004795:Enzyme Stability; D005947:Glucose / Q000032:analysis / Q000378:metabolism; D006602:Hexosyltransferases / Q000378:metabolism; D007218:Industrial Microbiology / Q000295:instrumentation* / Q000379:methods*; D009844:Oligosaccharides / Q000032:analysis / Q000378:metabolism*; D013395:Sucrose / Q000378:metabolism; D014312:Trisaccharides / Q000378:metabolism; D001426:Bacterial Proteins
chemical_list: D005947:Glucose; D006602:Hexosyltransferases; D009844:Oligosaccharides; D013395:Sucrose; D014312:Trisaccharides; C072433:1-kestose; C043600:fungitetraose; C021451:inulosucrase; D001426:Bacterial Proteins