title: Total synthesis of the bicyclic marine sesquiterpenoid drechslerine B.
abstract: The total synthesis of the recently isolated bicyclic sesquiterpenoid drechslerine B (2), isolated from the algicolous fungus Drechslera dematioidearare in the marine red alga Liagora viscida, has been achieved, starting from (S)-carvone (8), via an intramolecular aldol reaction and palladium-catalyzed carbon monoxide insertion as key reactions.
authors.affiliation: Graduate School of Science and Technology, Niigata University, 8050, 2-Nocho, Ikarashi, Nishi-ku, Niigata 950-2181, Japan. hagiwara@gs.niigata-u.ac.jp
authors.forename: Hisahiro
authors.initials: H
authors.lastname: Hagiwara
authors.forename: Masakazu
authors.initials: M
authors.lastname: Fukushima
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Kinugawa
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsui
authors.forename: Takashi
authors.initials: T
authors.lastname: Hoshi
authors.forename: Toshio
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism; D002248:Carbon Monoxide / Q000737:chemistry; D002384:Catalysis; D007202:Indicators and Reagents; D010126:Ozone / Q000737:chemistry; D010165:Palladium; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007202:Indicators and Reagents; D012717:Sesquiterpenes; C558332:drechslerine B; D010165:Palladium; D010126:Ozone; D002248:Carbon Monoxide