title: A novel heart valve stent design: mechanical interaction with the aortic root.
abstract: Percutaneous aortic valve implantation has become an alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Vascular stents clinically used today for non-invasive aortic valve replacement tend, however, to impede the dimension changes of the compliant aortic root over the cardiac cycle. The purpose of the present work is to assess the influence of a novel heart valve stent, designed specifically to limit the traumatism in tissue, on the compliance of the aortic root. A theoretical approach is adopted to model the mechanical behaviour of the different stent parts and assess the compliance modification induced by the stent. The validity of the model is then tested experimentally. Both approaches show that the specific geometry of the stent makes it possible to keep the compliance of the aortic root close to the native root values.
authors.affiliation: Laboratoire de Physique et Mécanique Textiles, ENSISA, 11 Rue Alfred Werner, 68093 Mulhouse, France. frederic.heim@uha.fr
authors.forename: Frederic
authors.initials: F
authors.lastname: Heim
authors.forename: Coralie
authors.initials: C
authors.lastname: Marchand
authors.forename: Bernard
authors.initials: B
authors.lastname: Durand
authors.forename: Nabil
authors.initials: N
authors.lastname: Chakfe
mesh_terms: D001011:Aorta / Q000502:physiology*; D006351:Heart Valves; D006801:Humans; D011474:Prosthesis Design; D015607:Stents