title: The role of radiation therapy in the control of locoregional and metastatic cancer.
abstract: High energy X-rays have been used for cancer therapy since their discovery in 1895. Major radiobiological discoveries and technological advances in radiation physics have greatly increased the accuracy of radiation. The recent integration of radiation therapy and imaging systems provides radiation oncologists with sophisticated dose delivery capability allowing continued improvements in the control of loco-regional and metastatic disease while decreasing toxicity. Key technical aspects of current radiation therapy are described with examples extending to several clinical areas.
authors.affiliation: Department of Radiation Oncology, University of Arizona, Tucson, Arizona 85724, USA. bstea@azcc.arizona.edu
authors.forename: Baldassarre
authors.initials: B
authors.lastname: Stea
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Hazard
authors.forename: Victor J
authors.initials: VJ
authors.lastname: Gonzalez
authors.forename: Russell
authors.initials: R
authors.lastname: Hamilton
mesh_terms: D001918:Brachytherapy; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000532:radiotherapy*; D016634:Radiosurgery; D018714:Radiotherapy, Adjuvant / Q000379:methods; D020266:Radiotherapy, Conformal; D013813:Therapy, Computer-Assisted / Q000379:methods*