title: Respiratory physiology at altitude.
abstract: The changes in respiratory physiology that occur with increasing altitude are driven by the fall in the partial pressure of oxygen that occurs with decreasing barometric pressure. At altitude, respiratory system changes occur which impact on each step of the oxygen cascade that occurs within the body. These changes are pivotal to the process of acclimatisation to altitude. The study of human respiratory physiology at altitude has the potential to produce research that will be translational to disease states characterised by hypoxaemia.
authors.affiliation: Anaesthetic Department, Norfolk and Norwich University Hospital, Colney Lane, Norwich. drbairsto@doctors.org.uk
authors.forename: C
authors.initials: C
authors.lastname: Sandberg
authors.forename: J
authors.initials: J
authors.lastname: Naylor
mesh_terms: D000064:Acclimatization / Q000502:physiology; D000531:Altitude; D006801:Humans; D009051:Mountaineering / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011652:Pulmonary Circulation; D012119:Respiration; D012143:Respiratory Physiological Phenomena; D014692:Ventilation-Perfusion Ratio
chemical_list: D010100:Oxygen