title: Diffusion tensor imaging for evaluation of the childhood brain and pediatric white matter disorders.
abstract: Magnetic resonance (MR) imaging has been used by investigators and clinicians to assess the development of the brain in childhood to understand both patterns of normal growth and patterns by which a maturing brain may deviate from normal. Advanced MR techniques such as diffusion tensor imaging (DTI) have gained prominence as a means of assessing brain development. This review explains the sequence of brain maturation and the means by which DTI can be used to assess it in normal children.
authors.affiliation: Duke University School of Medicine, 2301 Erwin Road, Durham, NC 27710, USA. jared.isaacson@duke.edu
authors.forename: Jared
authors.initials: J
authors.lastname: Isaacson
authors.forename: James
authors.initials: J
authors.lastname: Provenzale
mesh_terms: D001921:Brain / Q000254:growth & development* / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000473:pathology; D056324:Diffusion Tensor Imaging / Q000379:methods; D006801:Humans; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D010372:Pediatrics / Q000379:methods