title: Dosimetry of yttrium-labelled radiopharmaceuticals for internal therapy: 86Y or 90Y imaging?
abstract: This paper reviews issues concerning (86)Y positron emission tomography (PET), (90)Y PET and (90)Y bremsstrahlung imaging. Specific methods and corrections developed for quantitative imaging, for application in preclinical and clinical studies, and to assess (90)Y dosimetry are discussed. The potential imaging capabilities with the radioisotopes (87)Y and (88)Y are also considered. Additional studies required to assess specific unaddressed issues are also identified.
authors.affiliation: Center of Nuclear Medicine, Université Catholique de Louvain, Brussels, Belgium. Stephan.walrand@uclouvain.be
authors.forename: Stephan
authors.initials: S
authors.lastname: Walrand
authors.forename: Glenn D
authors.initials: GD
authors.lastname: Flux
authors.forename: Mark W
authors.initials: MW
authors.lastname: Konijnenberg
authors.forename: Roelf
authors.initials: R
authors.lastname: Valkema
authors.forename: Eric P
authors.initials: EP
authors.lastname: Krenning
authors.forename: Renaud
authors.initials: R
authors.lastname: Lhommel
authors.forename: Stanislas
authors.initials: S
authors.lastname: Pauwels
authors.forename: Francois
authors.initials: F
authors.lastname: Jamar
mesh_terms: D000818:Animals; D005544:Forecasting; D006207:Half-Life; D006801:Humans; D049268:Positron-Emission Tomography / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000493:pharmacokinetics; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D014018:Tissue Distribution; D014055:Tomography, Emission-Computed / Q000379:methods; D015021:Yttrium Radioisotopes / Q000008:administration & dosage* / Q000737:chemistry*
chemical_list: D019275:Radiopharmaceuticals; D015021:Yttrium Radioisotopes