title: Electrochemical sensing of L-histidine based on structure-switching DNAzymes and gold nanoparticle-graphene nanosheet composites.
abstract: A sensitive aptasensor for detection of L-histidine based on the switching structure of aptamer and gold nanoparticles-graphene nanosheets (GNPs-GNSs) composite was reported for the first time. The fabricated biosensor shows an expanded linear range, excellent sensitivity and selectivity against other amino acids.
authors.affiliation: School of Chemistry & Environment, Beijing University of Aeronautics & Astronautics, Beijing, 100191, PR China.
authors.forename: Junfei
authors.initials: J
authors.lastname: Liang
authors.forename: Zhengbo
authors.initials: Z
authors.lastname: Chen
authors.forename: Lin
authors.initials: L
authors.lastname: Guo
authors.forename: Lidong
authors.initials: L
authors.lastname: Li
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D021881:DNA, Catalytic / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D004563:Electrochemistry; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006639:Histidine / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation
chemical_list: D052157:Aptamers, Nucleotide; D021881:DNA, Catalytic; D006639:Histidine; D006046:Gold; D006108:Graphite