title: [Utility of Sp/Ap curve area ratio electrocochleography in diagnosis of Meniere's disease].
abstract: OBJECTIVE
  Comparison of the sensitivity of Sp/Ap amplitude and area ratio in the aid of diagnosis of Meniere's disease. Meniere's disease was defined by the 1995 American Academy of Otolaryngology-Head and Neck Surgery Committee on Hearing and Equilibrium.
  
  
  METHODS
  The study sample consisted of 35 patients in our hospital, who were undergone tympanic electrocochleography (EcochG). A control group of 10 patients (20 ears) with normal Sp/Ap ratio and EcochG data were identified. Sp/Ap amplitude and area curve ratios for both group were measured.
  
  
  RESULTS
  The traditional upper limit and the upper limit of normal for Sp/Ap amplitude and area curve were respectively 0.4, 46 and 1.94. Of 35 patients with Meniere's disease, had an abnormal Sp/Ap amplitude ratio,and had an abnormal Sp/Ap area curve ratio; the difference between groups was statistically significant.
  
  
  CONCLUSIONS
  Sp/Ap curve area curve ratio is more sensitive than conventional Sp/Ap amplitude ratios in diagnosis of Meniere's disease.
authors.affiliation: Institute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, 510120, China.
authors.forename: Qiuhong
authors.initials: Q
authors.lastname: Huang
authors.forename: Zeheng
authors.initials: Z
authors.lastname: Qiu
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Yongkang
authors.initials: Y
authors.lastname: Ou
authors.forename: Haidi
authors.initials: H
authors.lastname: Yang
authors.forename: Yiqing
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001300:Audiometry, Evoked Response; D016022:Case-Control Studies; D004710:Endolymph; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D055815:Young Adult