title: The communication of pharmacogenetic research results: participants weigh in on their informational needs in a pilot study.
abstract: In this brief investigation, the informational needs of research participants [n = 62; mothers who had breastfed, taken codeine, and participated in a pharmacogenetic study] were probed during a counselling session in which they received their CYP2D6 pharmacogenetic research results and overall study results. In addition to the standard information, developed by a multidisciplinary team and provided to the participants, 38% of individuals had further questions related to potential adverse effects in babies, future codeine or medication use, heredity, and consequences for policies and programmes. The diversity and complexity of the questions raised support the need to communicate the results in the context of personalized genetic counselling information sessions.
authors.affiliation: Division of Clinical Pharmacology and Toxicology, Toronto, Canada.
authors.forename: Parvaz
authors.initials: P
authors.lastname: Madadi
authors.forename: Yann
authors.initials: Y
authors.lastname: Joly
authors.forename: Denise
authors.initials: D
authors.lastname: Avard
authors.forename: David C
authors.initials: DC
authors.lastname: Chitayat
authors.forename: M Anne
authors.initials: MA
authors.lastname: Smith
authors.forename: Colin J
authors.initials: CJ
authors.lastname: D Ross
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Carleton
authors.forename: Michael R
authors.initials: MR
authors.lastname: Hayden
authors.forename: Gideon
authors.initials: G
authors.lastname: Koren
mesh_terms: D001942:Breast Feeding; D003061:Codeine / Q000378:metabolism*; D003142:Communication; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D005260:Female; D006801:Humans; D010597:Pharmacogenetics; D010865:Pilot Projects; D011247:Pregnancy
chemical_list: D019389:Cytochrome P-450 CYP2D6; D003061:Codeine