title: Medicine. Frightening risk of Marfan syndrome, and potential treatment, elucidated.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Couzin-Frankel
mesh_terms: D000818:Animals; D001014:Aortic Aneurysm / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D048049:Extracellular Signal-Regulated MAP Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D019808:Losartan / Q000494:pharmacology* / Q000627:therapeutic use; D020935:MAP Kinase Signaling System; D008382:Marfan Syndrome / Q000188:drug therapy* / Q000378:metabolism*; D051379:Mice; D047428:Protein Kinase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D015398:Signal Transduction; D016212:Transforming Growth Factor beta / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D047428:Protein Kinase Inhibitors; D016212:Transforming Growth Factor beta; D048049:Extracellular Signal-Regulated MAP Kinases; D019808:Losartan