title: Childhood intracranial germinoma with granulomatous reaction.
abstract: Central nervous system tumors are the second most common type of childhood cancer in Turkey. Germinomas constitute two thirds of intracranial germ cell tumors. The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. We present a 12-year-old girl with a diagnosis of germinoma in the corpus callosum associated with granulomatous reaction to emphasize the diagnostic challenge which may occur during stereotactic biopsy interpretation or intraoperative consultation.
authors.affiliation: Department of Pathology, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey. drgulen@ymail.com
authors.forename: Gülen Gül
authors.initials: GG
authors.lastname: Niflioğlu
authors.forename: Mehtat
authors.initials: M
authors.lastname: Unlü
authors.forename: Nurullah
authors.initials: N
authors.lastname: Yüceer
authors.forename: Erdener
authors.initials: E
authors.lastname: Ozer
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002648:Child; D003337:Corpus Callosum / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D005260:Female; D018237:Germinoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006099:Granuloma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging
chemical_list: D014408:Biomarkers, Tumor