title: Izumiphenazine D, a new phenazoquinoline N-oxide from Streptomyces sp. IFM 11204.
abstract: A new phenazine derivative named izumiphenazine D (1), together with three known metabolites, 1-hydroxyphenazine (2), phenazine-1-carboxylic acid (3) and 6-hydroxyphenazine-1-carboxylic acid (4) has been isolated from the ethyl acetate extract of culture of Streptomyces sp. IFM 11204. The structure of 1 was established via spectroscopic methods, including 1D- and 2D-NMR measurements.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University, 1–33 Yayoi-cho, Inage-ku, Chiba, Japan.
authors.forename: Mohamed S
authors.initials: MS
authors.lastname: Abdelfattah
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Toume
authors.forename: Masami
authors.initials: M
authors.lastname: Ishibashi
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D008968:Molecular Conformation; D010087:Oxides / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D011804:Quinolines / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D013302:Streptomyces / Q000737:chemistry*; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000494:pharmacology
chemical_list: D010087:Oxides; D011804:Quinolines; D053221:TNF-Related Apoptosis-Inducing Ligand; C559420:izumiphenazine D; C037219:quinoline