title: New pharmacological treatments for patients with chronic obstructive pulmonary disease (COPD).
abstract: BACKGROUND
  Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable disease characterized mainly by pulmonary airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with abnormal inflammatory response of the lung to noxious particles or gasses. New different pharmacological approaches to decrease inflammation of the airways and consequently disease progression and increase airway obstruction reversibility have been developed.
  
  
  RESULTS
  A literature search using PubMed, Science Direct, EBSCO and free patents on line for the years 2000-2010.
  
  
  CONCLUSIONS
  Recent discoveries in the physiology and pathology of airways diseases have served to generate potential new drugs for the treatment of COPD patients. Several substances that block or activate specific pathways and receptors the aim of which is to decrease inflammation and increase airway obstruction reversibility are being used in different clinical protocols and hopefully will be available for patients in the near future.
authors.affiliation: Department of Pathology and Physiopathology, Experimental Medicine Institute, Faculty of Medicine, Universidad Central de Venezuela, Venezuela.
authors.forename: Nancy Elizabeth
authors.initials: NE
authors.lastname: Larocca
authors.forename: Dolores
authors.initials: D
authors.lastname: Moreno
authors.forename: Jenny Valentina
authors.initials: JV
authors.lastname: Garmendia
authors.forename: Juan Bautista
authors.initials: JB
authors.lastname: De Sanctis
mesh_terms: D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*