title: Epidemiological, clinical and laboratory profile of glucose-6-phosphate dehydrogenase deficiency in the middle and north of Iraq: a comparative study.
abstract: This study determined the epidemiological, clinical and laboratory profile of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Baghdad (central Iraq) and compared it with previous data from Mosul (northern Iraq). We reviewed the records of 156 under-5-year-olds with G6PD deficiency admitted to 3 hospitals in Baghdad over a 6-year period. A preponderance of males was noted in both Baghdad and Mosul (1.6:1 and 3.4:1 respectively). Family history of G6PD deficiency was positive in 19.2% of patients in Baghdad and 13.6% in Mosul. A majority of patients in Baghdad (69.2%) and Mosul (76.1%) showed haemolysis within 1-3 days of exposure to noxious agents. Similarities in the profiles from Baghdad and Mosul suggest that there are similar G6PD variants and similar exposure to precipitating agents.
authors.affiliation: Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq. mdalmendalawi@yahoo.com
authors.forename: M D
authors.initials: MD
authors.lastname: Al-Mendalawi
mesh_terms: D001772:Blood Cell Count; D001774:Blood Chemical Analysis; D002675:Child, Preschool; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D006461:Hemolysis; D006801:Humans; D007223:Infant; D007493:Iraq / Q000453:epidemiology; D008297:Male; D017678:Sex Distribution