title: Polyhedral silver mesocages for single particle surface-enhanced Raman scattering-based biosensor.
abstract: Surface-enhanced Raman scattering-based signal detection and molecular identification faces the lack of reproducibility and reliability thus hampers its practical applications. Here, we demonstrate a facile particle mediated aggregation protocol to synthesize highly roughened mesosuperstructure--silver polyhedral mesocages. The individual silver octahedral mesocage, owing to highly-roughed surface topography, anisotropic growth as well as intraparticle effect, creates homogenously distributed multiple effective hot spots on the surface of single mesoparticle, hereby exhibits a high reproducibility and an unusual SERS enhancement, i.e., ∼ 10(8)-10(9) magnitude. As such, the current protocol opens avenues for the fabrication of structurally reproducible mesosuperstructure-based SERS sensors.
authors.affiliation: School of Science, 'Xi'an Jiaotong University, Shann Xi 710049, People's Republic of China. jxfang@mail.xjtu.edu.cn
authors.forename: Jixiang
authors.initials: J
authors.lastname: Fang
authors.forename: Siyun
authors.initials: S
authors.lastname: Liu
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Li
mesh_terms: D015374:Biosensing Techniques; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties; D014961:X-Ray Diffraction
chemical_list: D012834:Silver