title: Nanotoxicity of gold and iron nanoparticles.
abstract: The extensive use of potentially hazardous nanoparticles in industrial applications suggest that their biological effects need to be evaluated following clinical testing practices as applicable for any new pharmaceutical. It was rationalized that a non hypothesis-driven approach is best suited for discovering the biological effects of nanoparticles. Gold nanoparticles (approximately 18 nm), showed no drastic effect on gene expression in cells but iron nanoparticles showed perturbations in the expression of a set of functional genes.
authors.affiliation: Institute of Genomics and Integrative Biology, (Council of Scientific and Industrial Research, India), Delhi 110007, India.
authors.forename: Souvik
authors.initials: S
authors.lastname: Maiti
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006046:Gold / Q000633:toxicity*; D006801:Humans; D007501:Iron / Q000633:toxicity*; D053758:Nanoparticles / Q000633:toxicity*
chemical_list: D006046:Gold; D007501:Iron