title: The tobacco industry's past role in weight control related to smoking.
abstract: BACKGROUND
  Smoking is thought to produce an appetite-suppressing effect by many smokers. Thus, the fear of body weight gain often outweighs the perception of health benefits associated with smoking cessation, particularly in adolescents. We examined whether the tobacco industry played a role in appetite and body weight control related to smoking and smoking cessation.
  
  
  METHODS
  We performed a systematic search within the archives of six major US and UK tobacco companies (American Tobacco, Philip Morris, RJ Reynolds, Lorillard, Brown & Williamson and British American Tobacco) that were Defendants in tobacco litigation settled in 1998. Findings are dated from 1949 to 1999.
  
  
  RESULTS
  The documents revealed the strategies planned and used by the industry to enhance effects of smoking on weight and appetite, mostly by chemical modifications of cigarettes contents. Appetite-suppressant molecules, such as tartaric acid and 2-acetylpyridine were added to some cigarettes.
  
  
  CONCLUSIONS
  These tobacco companies played an active and not disclaimed role in the anti-appetite effects of smoking, at least in the past, by adding appetite-suppressant molecules into their cigarettes.
authors.affiliation: Department of Ambulatory Care and Community Medicine, Lausanne University Hospital, Switzerland. semira.gonseth@gmail.com
authors.forename: Semira
authors.initials: S
authors.lastname: Gonseth
authors.forename: Isabelle
authors.initials: I
authors.lastname: Jacot-Sadowski
authors.forename: Pascal A
authors.initials: PA
authors.lastname: Diethelm
authors.forename: Vincent
authors.initials: V
authors.lastname: Barras
authors.forename: Jacques
authors.initials: J
authors.lastname: Cornuz
mesh_terms: D000293:Adolescent; D001067:Appetite Depressants / Q000009:adverse effects*; D006801:Humans; D011725:Pyridines / Q000009:adverse effects; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D013644:Tartrates / Q000009:adverse effects; D019460:Tobacco Industry / Q000941:ethics*; D006113:United Kingdom; D014481:United States; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D001067:Appetite Depressants; D011725:Pyridines; D013644:Tartrates; C543930:2-acetylpyridine; C029768:tartaric acid