title: A comparative study: diffusion weighted whole body imaging with background body signal suppression and hybrid Positron Emission Computed Tomography on detecting lesions in oncologic clinics.
abstract: OBJECTIVE
  To compare diffusion weighted whole body imaging with background body signal suppression (DWIBS) with hybrid Positron Emission Computed Tomography (HPET/CT) on clinical value in oncology.
  
  
  METHODS
  43 patients with oncological diseases were enrolled in our hospital from October, 2008 to April, 2010. All the cases underwent DWIBS and HPET/CT within 14 days. Combined with other imagings, lesions detected by both modalities were evaluated. Lesions were confirmed by pathology, cytology or clinical diagnosis (needed no less than 6 months and three times follow-up).
  
  
  RESULTS
  The overall detection rate of the DWIBS and HPET/CT were 90.3% (261/289), 86.6% (251/289), concordant ratio of the two modalities was 88.2% (255/289). There was no statistical difference between DWIBS and HPET/CT on detecting lesions (P>0.05). HPET/CT was significantly more sensitive in detecting lesions in lung (P<0.05), whereas DWIBS was more sensitive in identifying lesions in brain and bone (P<0.05). With regard to finding lesions in liver and lymph node, the two procedures had no significant difference (P>0.05).
  
  
  CONCLUSIONS
  DWIBS and HPET/CT have a certain degree of consistency in terms of identifying lesions. However, they have advantages and disadvantages in some organs or tissues, which should be taken into full consideration in clinical practice.
authors.affiliation: Oncology Department, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province 230601, China.
authors.forename: Nianfei
authors.initials: N
authors.lastname: Wang
authors.forename: Mingjun
authors.initials: M
authors.lastname: Zhang
authors.forename: Tong
authors.initials: T
authors.lastname: Sun
authors.forename: Huaidong
authors.initials: H
authors.lastname: Chen
authors.forename: Zhonglian
authors.initials: Z
authors.lastname: Huang
authors.forename: Long
authors.initials: L
authors.lastname: Yan
authors.forename: Longsheng
authors.initials: L
authors.lastname: Wang
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging