title: Analysis of the effects of irradiation in osseointegrated dental implants.
abstract: OBJECTIVE
  The purpose of the present study was to evaluate the influence of radiation in osseointegrated dental implants installed in tibiae of rats.
  
  
  METHODS
  Screw-shaped implants (2.5 mm diameter by 3.5 mm length) were custom made from commercially pure titanium bars. Titanium implants were blasted and sterilized before implantation. Animals were divided into two groups of 12 animals each and the rats were not paired after the groups' formation. The experimental group (group 1) received external irradiation 4 weeks after surgery while in the control group (group 2) animals were kept free of radiation. The shear strength required to detach the implant from bone was measured by push-out testing and osseointegration was histologically evaluated.
  
  
  RESULTS
  Results showed that the compressive strength of irradiated implants (33.49 MPa) was significantly lower than the compressive strength of non-irradiated implants (48.05 MPa).
  
  
  CONCLUSIONS
  We concluded that the mechanical strength bonding between implants and host tissues decreased after irradiation.
authors.affiliation: Department of Materials and Technology, UNESP, Univ. Estadual Paulista, Guaratinguetá Campus, Guaratinguetá, SP, Brazil.
authors.forename: João Augusto Guedes
authors.initials: JA
authors.lastname: de Oliveira
authors.forename: Ana Lúcia
authors.initials: AL
authors.lastname: do Amaral Escada
authors.forename: Maria Cristina Rosifini
authors.initials: MC
authors.lastname: Alves Rezende
authors.forename: Monica Beatriz
authors.initials: MB
authors.lastname: Mathor
authors.forename: Ana Paula Rosifini
authors.initials: AP
authors.lastname: Alves Claro
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001863:Bone Screws; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D020007:Implants, Experimental; D008297:Male; D016348:Osseointegration / Q000528:radiation effects*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D018709:Statistics, Nonparametric; D013499:Surface Properties; D013977:Tibia / Q000528:radiation effects* / Q000601:surgery*; D014025:Titanium
chemical_list: D015921:Dental Implants; D014025:Titanium