title: Carbonylative Heck reactions using CO generated ex situ in a two-chamber system.
abstract: A carbonylative Heck reaction of aryl iodides and styrene derivatives employing a two-chamber system using a stable, crystalline, and nontransition metal based carbon monoxide source is reported. By applying near-stoichiometric amounts of the carbon monoxide precursor, an effective exploitation of the hazardous CO gas is obtained affording chalcone derivatives in good yields. Application to isotope labeling, incorporating (13)CO, was further established.
authors.affiliation: Center for Insoluble Protein Structures (inSPIN), Department of Chemistry and the Interdisciplinary Nanoscience Center, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors.forename: Philippe
authors.initials: P
authors.lastname: Hermange
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Gøgsig
authors.forename: Anders T
authors.initials: AT
authors.lastname: Lindhardt
authors.forename: Rolf H
authors.initials: RH
authors.lastname: Taaning
authors.forename: Troels
authors.initials: T
authors.lastname: Skrydstrup
mesh_terms: D002248:Carbon Monoxide / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D002248:Carbon Monoxide