title: Risk factors in Dupuytren's diathesis: is recurrence after surgery predictable?
abstract: In order to investigate the prognostic value of possible risk factors for Dupuytren's diathesis, clinical parameters on disease presentation in an operated group of patients were compared with self-reported recurrence after a minimum 2 years follow-up. In order of significance, the following factors were found to be significantly correlated with disease recurrence : age of onset under 50 years (p = 0.01), bilateral disease (p = 0.01), Ledderhose disease (p = 0.01), first ray involvement (p = 0.02), multiple ray involvement (more than 2 digits, p = 0.02), ectopic fibromatosis (p = 0.02), family occurrence (p = 0.04) and male gender (p = 0.05). No correlation of self-reported disease recurrence was seen with diabetes, frozen shoulder syndrome or epilepsy. An insight in the significance of the influence of specific risk factors on recurrence rates, helps in creating a clearer representation of Dupuytren's diathesis. This will help the surgeon to more accurately inform the patient and possibly to reconsider and adjust the choice in treatment options.
authors.affiliation: Department of Orthopaedic Surgery, Upper Limb Surgery, University Hospitals of Leuven, Pellenberg Campus, Pellenberg, Belgium. Ilse.degreef@uz.kuleuven.ac.be
authors.forename: Ilse
authors.initials: I
authors.lastname: Degreef
authors.forename: Luc
authors.initials: L
authors.lastname: De Smet
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D004387:Dupuytren Contracture / Q000150:complications / Q000601:surgery*; D005260:Female; D005350:Fibroma / Q000150:complications; D005534:Foot Diseases / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors; D011795:Surveys and Questionnaires