title: [Endoscopic treatments for Barrett oesophagus].
abstract: High grade dysplasia and superficial carcinomas (with no extension under muscularis mucosae) can be indications for endoscopic treatments of Barrett oesophagus. When an endoscopic treatment is considered, a gastroscopy with use of acetic acid and planimetry and the confirmation of high-grade dysplasia by a new examination after PPI treatment and a pathologic second confirmation is needed. For high-grade dysplasia in focalised and visible lesions, an endoscopic resection by EMR or ESD should be proposed: it allows a more accurate pathologic examination and can be an effective curative treatment. After endoscopic resection of visible high grade dysplasia lesions, a complete eradication of Barrett oesophagus may be proposed to prevent dysplasia recurrence. In case of extensive high-grade dysplasia or to eradicate Barrett oesophagus residual lesions, radiofrequency ablation is the preferred endoscopic technique. Photodynamic therapy may also be proposed for more invasive lesions or after other endoscopic techniques with mucosal scars. Surgical oesophagus resection is still recommended for diffuse high-grade dysplasia in young patients or in case of pathologic pejorative criteria in endoscopic resection specimen. In case of Low-grade dysplasia, either endoscopic surveillance should be performed every six or 12 months or radiofrequency ablation could be proposed in the yield of prospective studies.
authors.affiliation: Assistance publique-Hôpitaux de Paris, hôpital Cochin, service de gastro-entérologie, 75014 Paris, France. Ariane.vienne@cch.aphp.fr
authors.forename: Ariane
authors.initials: A
authors.lastname: Vienne
authors.forename: Frédéric
authors.initials: F
authors.lastname: Prat
mesh_terms: D000465:Algorithms; D001471:Barrett Esophagus / Q000628:therapy*; D017115:Catheter Ablation / Q000295:instrumentation; D003452:Cryosurgery; D004867:Equipment Design; D004938:Esophageal Neoplasms / Q000628:therapy; D004945:Esophagoscopy / Q000379:methods; D006801:Humans; D010778:Photochemotherapy