title: The impact of early percutaneous endoscopic gastrostomy placement on treatment completeness and nutritional status in locally advanced head and neck cancer patients receiving chemoradiotherapy.
abstract: To investigate the impact of early insertion of percutaneous endoscopic gastrostomy-tube on nutritional status and completeness of concurrent chemotherapy in locally advanced head and neck cancer patients treated with chemoradiotherapy. Twenty-three patients were enrolled into this prospective study. Gastrostomy-tube was inserted in patients before the initiation of chemoradiotherapy. There was not any significant change in nutritional parameters of patients that used their tube during treatment. Despite the grade 3 mucositis, the planned concurrent chemotherapy could be given in 70% of the patients. However, nine patients had weak compliance and their body weight (P = 0.01) and body mass index (P = 0.01) deteriorated in the first 4 weeks of chemoradiotherapy. The completeness of concurrent chemo-rate was 44% in these patients. Toxicity, requiring aggressive supportive care, may limit the chemotherapy part of curative concomitant chemoradiotherapy. By providing adequate enteral nutrition the insertion of gastrostomy-tube can increase the completeness rate of concurrent chemotherapy.
authors.affiliation: S.B. Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi, Fevzi Cakmak mah. Mimar Sinan cad No 41, Ust Kaynarca Pendik, 34899 Istanbul, Turkey. bmatasoy@yahoo.com
authors.forename: Beste M
authors.initials: BM
authors.lastname: Atasoy
authors.forename: Oya
authors.initials: O
authors.lastname: Yonal
authors.forename: Birsen
authors.initials: B
authors.lastname: Demirel
authors.forename: Faysal
authors.initials: F
authors.lastname: Dane
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yilmaz
authors.forename: Cem
authors.initials: C
authors.lastname: Kalayci
authors.forename: Ufuk
authors.initials: U
authors.lastname: Abacioglu
authors.forename: Nese
authors.initials: N
authors.lastname: Imeryuz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D059248:Chemoradiotherapy / Q000009:adverse effects; D020878:Device Removal; D004724:Endoscopy; D004750:Enteral Nutrition; D005260:Female; D005774:Gastrostomy / Q000009:adverse effects; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D009752:Nutritional Status; D010039:Otorhinolaryngologic Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D015431:Weight Loss; D055815:Young Adult