title: Nanotoxicity of dolomite mineral of commercial importance in India.
abstract: The risk of occupational exposure to dolomite, an important mineral exists both in organized as well as unorganized sectors. Toxicological profiles of bulk dolomite are meagerly known in general and its nanotoxicity in particular. Effects of micro- and nano particles on cell viability, LDH leakage and markers of oxidative stress were observed. The study indicated that cytotoxicity of dolomite nanoparticles is significantly higher than the microparticles. The study thus suggests for the prescription of exposure limit for nanodolomite in the best interest of health of workers at risk of exposure under mining, milling and industrial environment.
authors.affiliation: Nanomaterial Toxicology Group, Indian Institute of Toxicology Research (CSIR), M. G. Marg, Lucknow 226001, India.
authors.forename: Govil
authors.initials: G
authors.lastname: Patil
authors.forename: Mohd Imran
authors.initials: MI
authors.lastname: Khan
authors.forename: Mohd Javed
authors.initials: MJ
authors.lastname: Akhtar
authors.forename: Mohd
authors.initials: M
authors.lastname: Ashquin
authors.forename: Sarwat
authors.initials: S
authors.lastname: Sultana
authors.forename: Iqbal
authors.initials: I
authors.lastname: Ahmad
mesh_terms: D002119:Calcium Carbonate / Q000633:toxicity*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D007194:India; D008175:Lung Neoplasms / Q000473:pathology / Q000503:physiopathology*; D008274:Magnesium / Q000633:toxicity*; D008422:Materials Testing; D008906:Mining; D049329:Nanostructures / Q000633:toxicity*
chemical_list: D002119:Calcium Carbonate; D008274:Magnesium; C028042:calcium magnesium carbonate