title: Selective activation of enantiotopic C(sp3)-hydrogen by means of chiral phosphoric acid: asymmetric synthesis of tetrahydroquinoline derivatives.
abstract: Chiral phosphoric acid-catalyzed asymmetric C-H functionalization has been achieved. In this process, enantiotopic C(sp(3))-hydrogen is selectively activated by chiral phosphoric acid to afford tetrahydroquinoline derivatives with excellent enantioselectivities (up to 97% ee).
authors.affiliation: Department of Chemistry, Faculty of Science, Gakushuin University, Mejiro, Toshima-ku, Tokyo 171-8588, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Mori
authors.forename: Kensuke
authors.initials: K
authors.lastname: Ehara
authors.forename: Kazuki
authors.initials: K
authors.lastname: Kurihara
authors.forename: Takahiko
authors.initials: T
authors.lastname: Akiyama