title: Flow-induced translocation of polymers through a fluidic channel: a dissipative particle dynamics simulation study.
abstract: The dynamics of flow-induced translocation of polymers through a fluidic channel has been studied by dissipative particle dynamics (DPD) approach. Unlike implicit solvent models, the many-body energetic and hydrodynamic interactions are preserved naturally by incorporating explicit solvent particles in this approach. The no-slip wall boundary and the adaptive boundary conditions have been implemented in the modified DPD approach to model the hydrodynamic flow within a specific wall structure of fluidic channel and control the particles' density fluctuations. The results show that the average translocation time versus polymer chain length satisfies a power-law scaling of τ ∼N(1.152). The conformational changes and translocation dynamics of polymers through the fluidic channel have also been investigated in our simulations, and two different translocation processes, i.e., the single-file and double-folded translocation events, have been observed in detail. These findings may be helpful in understanding the conformational and dynamic behaviors of such polymer and/or DNA molecules during the translocation processes.
authors.affiliation: CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
authors.forename: Jiayi
authors.initials: J
authors.lastname: Guo
authors.forename: Xuejin
authors.initials: X
authors.lastname: Li
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liu
authors.forename: Haojun
authors.initials: H
authors.lastname: Liang
mesh_terms: D003198:Computer Simulation; D004247:DNA / Q000737:chemistry; D057446:Hydrodynamics; D044085:Microfluidics; D008956:Models, Chemical; D009038:Motion; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; D004247:DNA