title: Responsiveness of children with celiac disease to different hepatitis B vaccination protocols.
abstract: OBJECTIVE
  We aimed to compare the response rates to hepatitis B virus vaccination in the first year of life, using two different immunization protocols, in children with celiac disease.
  
  
  METHODS
  Study Group 1 included patients with celiac disease who received 10 μg of hepatitis B vaccine intramuscularly at birth (0), 2 and 9-12 months of life. Group 2 included those who received hepatitis B vaccine at 0, 1 and 6 months of life. Healthy children were divided into two control groups according to the above schedules.
  
  
  RESULTS
  The total study group included 64 patients and 49 healthy controls. Celiac patients were found to have lower response rates with respect to controls (78.1% vs. 95.9%, respectively). The difference in response rates in the two patient groups was not statistically significant.
  
  
  CONCLUSIONS
  The response rates of celiac patients to the two different hepatitis B vaccination schedules showed no statistically significant difference.
authors.affiliation: Department of Pediatrics, Section of Gastroenterology, Hacettepe University School of Medicine, Ankara.
authors.forename: Necati
authors.initials: N
authors.lastname: Balamtekın
authors.forename: Nuray
authors.initials: N
authors.lastname: Uslu
authors.forename: Gökhan
authors.initials: G
authors.lastname: Baysoy
authors.forename: Inci
authors.initials: I
authors.lastname: Saltik-Temızel
authors.forename: Hülya
authors.initials: H
authors.lastname: Demır
authors.forename: Aysel
authors.initials: A
authors.lastname: Yüce
mesh_terms: D002446:Celiac Disease / Q000276:immunology*; D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D006801:Humans; D017589:Immunization Programs / Q000379:methods*; D007223:Infant; D008297:Male
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines