title: Serratia marcescens bacteremia because of contaminated prefilled heparin and saline syringes: a multi-state report.
abstract: A national outbreak of Serratia marcescens bacteremia because of contaminated prefilled heparin and saline syringes led to their recall. We evaluated the clinical impact of this outbreak in 57 patients at 3 centers. All patients were symptomatic and were treated with intravenous antibiotics with a fatal outcome in 1 patient.
authors.affiliation: University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4009, USA. rfchemaly@mdanderson.org
authors.forename: Roy F
authors.initials: RF
authors.lastname: Chemaly
authors.forename: Dhanesh B
authors.initials: DB
authors.lastname: Rathod
authors.forename: Monica K
authors.initials: MK
authors.lastname: Sikka
authors.forename: Mary K
authors.initials: MK
authors.lastname: Hayden
authors.forename: Mark
authors.initials: M
authors.lastname: Hutchins
authors.forename: Tracy
authors.initials: T
authors.lastname: Horn
authors.forename: Jeffery
authors.initials: J
authors.lastname: Tarrand
authors.forename: Javier
authors.initials: J
authors.lastname: Adachi
authors.forename: Kim
authors.initials: K
authors.lastname: Nguyen
authors.forename: Gorden
authors.initials: G
authors.lastname: Trenholme
authors.forename: Issam
authors.initials: I
authors.lastname: Raad
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004340:Drug Contamination; D005260:Female; D006493:Heparin; D006801:Humans; D008297:Male; D008875:Middle Aged; D016868:Serratia Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D012706:Serratia marcescens / Q000302:isolation & purification*; D012965:Sodium Chloride; D013594:Syringes / Q000382:microbiology; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D012965:Sodium Chloride; D006493:Heparin