title: Current status on natural products with antitumor activity from Brazilian marine sponges.
abstract: Over the last few years, samples from the marine environment have been screened for a variety of compounds with different biological activities. Among all marine organisms, sponges represent one of the most promising sources of leads in the research of new cancer drugs. However, there are few reports on screening Brazilian marine sponges for biological activities. In the following review, the current status of natural product research relating to Brazilian marine sponges is summarized, particularly for compounds demonstrating potential antitumor activity.
authors.affiliation: Centro de Estudos em Estresse Oxidativo (CEEO), ICBS-UFRGS, Porto Alegre, Brazil.
authors.forename: Mario Junior Luiz Conte da
authors.initials: MJ
authors.lastname: Frota
authors.forename: Renata Biegelmeyer da
authors.initials: RB
authors.lastname: Silva
authors.forename: Beatriz
authors.initials: B
authors.lastname: Mothes
authors.forename: Amelia Teresinha
authors.initials: AT
authors.lastname: Henriques
authors.forename: Jose Claudio Fonseca
authors.initials: JC
authors.lastname: Moreira
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001688:Biological Products / Q000494:pharmacology*; D001938:Brazil; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D011161:Porifera
chemical_list: D000970:Antineoplastic Agents; D001688:Biological Products