title: Direct detection of uric acid in body fluid samples by using boron doped graphite nano particles as the working electrode.
abstract: Boron doped graphite nano particles were used as functioning elements for creation of electrodes for the detection of uric acid in biological samples. The electrode obtained in this manner was capable of oxidizing ascorbic acid at lower potentials. This provided a desirable solution to the interfering problem encountered in the detection of uric acid in biological samples caused by ascorbic acid. The detectable concentrations for uric acid ranged from 5.0 to 130 µM. The applicability of the electrode was experimentally demonstrated by the successful direct detection of uric acid in real urine samples.
authors.affiliation: Laboratory of Environmental Remediation, Graduate School of Environmental Science, Hokkaido University, Sapporo, Japan.
authors.forename: Jianjun
authors.initials: J
authors.lastname: He
authors.forename: Bunshi
authors.initials: B
authors.lastname: Fugetsu
authors.forename: Shunitz
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D001826:Body Fluids / Q000737:chemistry*; D001895:Boron / Q000737:chemistry*; D002138:Calibration; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D015203:Reproducibility of Results; D014527:Uric Acid / Q000032:analysis* / Q000737:chemistry / Q000652:urine
chemical_list: D014527:Uric Acid; D006108:Graphite; D001895:Boron