title: Bilateral upper and lower eyelid severe psoriasiform blepharitis: case report and review of literature.
abstract: The purpose of the present study is to describe a case of severe, psoriasiform blepharitis by means of a case report and literature review. A 44-year-old man developed chronic blepharitis and tearing months after bilateral cataract surgery. Exam showed diffuse quad-eyelid erythema, discharge, edema, madarosis, and scale. He also had insufficient tear drainage due to bilateral upper eyelid cicatricial punctal atresia with bilateral lower eyelid punctal stenosis. Biopsy of the lower eyelids exhibited psoriasiform hyperplasia. Topical 0.1% tacrolimus achieved improvement but caused some subjective eye irritation. Psoriasiform dermatitis manifesting on the eyelids is rare, may be associated with insufficient tear drainage, and may respond favorably to 0.1% tacrolimus.
authors.affiliation: The Gavin Herbert Eye Institute, University of California, Irvine, CA, USA. fzhu@uci.edu
authors.forename: Feilin
authors.initials: F
authors.lastname: Zhu
authors.forename: Jeremiah P
authors.initials: JP
authors.lastname: Tao
mesh_terms: D000328:Adult; D001762:Blepharitis / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D011565:Psoriasis / Q000150:complications*; D016559:Tacrolimus / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus