title: [Effect of heparin on the neuron bioelectric activity in a hemorrhagic stroke model in vitro].
abstract: The effect of heparin on the activity of cerebral neurons under conditions of hemorrhagic stroke model was studied in vitro using brain slices of hypertensive rats. The auto-blood induced blocking of the parameters of focal potentials in neurons. The treatment with heparin (25 IU/ml) prior to the auto-blood action prevented inhibition of the activity of ionotropic glutamatergic and GABAergic receptors.
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Khama-Murad
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology*; D001769:Blood; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D004558:Electric Stimulation; D005071:Evoked Potentials; D006493:Heparin / Q000494:pharmacology*; D020300:Intracranial Hemorrhages / Q000503:physiopathology*; D008297:Male; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D018696:Neuroprotective Agents / Q000494:pharmacology*; D009833:Olfactory Pathways / Q000187:drug effects / Q000503:physiopathology; D051381:Rats; D011918:Rats, Inbred SHR; D018091:Receptors, AMPA / Q000502:physiology; D018080:Receptors, GABA-B / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D020521:Stroke / Q000503:physiopathology*
chemical_list: D000925:Anticoagulants; D018696:Neuroprotective Agents; D018091:Receptors, AMPA; D018080:Receptors, GABA-B; D016194:Receptors, N-Methyl-D-Aspartate; D006493:Heparin