title: [Advances in effector protein of histone methylation].
abstract: As a significant epigenetic regulation mechanism, histone methylation plays an important role in many biological processes. In cells, there are various histone methyltransferases and histone demethylases working cooperatively to regulate the histone methylation state. Upon histone modification, effector proteins recognize modification sites specifically, and affect gene transcriptional process. This review mainly focuses on recent advances in histone methylation effector protein's function mechanism.
authors.affiliation: Department of Biochemistry and Molecular Biology, Health Science Center, Peking University, Beijing 100191, China. songboyan@bjmu.edu.cn
authors.forename: Bo-Yan
authors.initials: BY
authors.lastname: Song
authors.forename: Wei-Guo
authors.initials: WG
authors.lastname: Zhu
mesh_terms: D000818:Animals; D044127:Epigenesis, Genetic; D056466:Histone Demethylases / Q000502:physiology; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase / Q000502:physiology; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008745:Methylation
chemical_list: D006657:Histones; D056466:Histone Demethylases; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase