title: [Effect of a novel compound BIV-30 on bone-marrow hematopoiesis in myelosuppression induced by lead acetate].
abstract: The Intraperitoneal injection of lead acetate in a daily doze of 50 mg/kg for 10 days led to the development of myelosuppression of the bone-marrow pool in mice. On the background of this immunodepressive syndrome, the treatment with B1V-309 azaheterocycle during 3 days reliably accelerated the regeneration of neutrophiles, lymphocytes, and monocyte cells in bone marrow. The results shown evidence of the hemostimulating activity of BIV-30 on the model of bone-marrow hemopoiesis deficiency.
authors.forename: L K
authors.initials: LK
authors.lastname: Baktybaeva
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D001853:Bone Marrow / Q000187:drug effects* / Q000473:pathology; D049109:Cell Proliferation; D004912:Erythrocytes / Q000187:drug effects / Q000473:pathology; D005260:Female; D006098:Granulocytes / Q000187:drug effects / Q000473:pathology; D006410:Hematopoiesis / Q000187:drug effects*; D007978:Levamisole / Q000494:pharmacology; D008214:Lymphocytes / Q000187:drug effects / Q000473:pathology; D008297:Male; D051379:Mice; D009025:Morpholines / Q000737:chemistry / Q000494:pharmacology*; D009942:Organometallic Compounds / Q000633:toxicity*; D014873:Water Pollutants / Q000633:toxicity*; D047392:beta-Cyclodextrins / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D009025:Morpholines; D009942:Organometallic Compounds; D014873:Water Pollutants; D047392:beta-Cyclodextrins; D007978:Levamisole; C031215:betadex; C008261:lead acetate