title: [Role and place of biochemical markers in diagnosis of cerebral ischemic stroke].
abstract: In recent years neurologists pay special attention to biochemical markers of instrumental diagnosis of brain ischemia in its acute phase. Determination of specific biomarkers in the blood of patients at early stages of cerebral blood circulation disorders may be helpful in screening patients at high risk of stroke in the short-term period. We present a review of literature and an analysis of own data (over 200 patients) with chronic and acute cerebral blood circulation disorders on the possibility of using brain biomarkers in clinical practice. The diagnostic value of NR2-antibodies in stroke with ischemic volume 5-70 cm3 is approximately 95,9% and in transitory ischemic attacks--98%.
authors.forename: S A
authors.initials: SA
authors.lastname: Dambinova
authors.forename: A A
authors.initials: AA
authors.lastname: Skoromets
authors.forename: A P
authors.initials: AP
authors.lastname: Skoromets
authors.forename: T A
authors.initials: TA
authors.lastname: Skoromets
authors.forename: M V
authors.initials: MV
authors.lastname: Shumilina
mesh_terms: D000906:Antibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*; D020521:Stroke / Q000097:blood* / Q000175:diagnosis*
chemical_list: D000906:Antibodies; D015415:Biomarkers; C120997:NR2A NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate