title: Acute generalised exanthematous pustulosis following intravitreal Ranibizumab.
abstract: Acute generalised exanthematous pustulosis, or AGEP, is a well documented cutaneous drug reaction. It typically occurs within 48 hours of oral antibiotics, but can be caused by other medications and, occasionally, after viral infections. We present a case of AGEP following intravitreal injection of Ranibizumab, a monoclonal antibody vascular endothelial growth factor inhibitor.
authors.affiliation: Department of Dermatology and Wound Healing, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.
authors.forename: David C
authors.initials: DC
authors.lastname: Bosanquet
authors.forename: Wendy L
authors.initials: WL
authors.lastname: Davies
authors.forename: Kenneth
authors.initials: K
authors.lastname: May
authors.forename: Keith G
authors.initials: KG
authors.lastname: Harding
authors.forename: Girish K
authors.initials: GK
authors.lastname: Patel
mesh_terms: D056150:Acute Generalized Exanthematous Pustulosis / Q000139:chemically induced* / Q000473:pathology; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000009:adverse effects*; D061067:Antibodies, Monoclonal, Humanized; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D058449:Intravitreal Injections; D008268:Macular Degeneration / Q000175:diagnosis / Q000188:drug therapy*; D008991:Monitoring, Physiologic; D000069579:Ranibizumab; D018570:Risk Assessment; D012720:Severity of Illness Index
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000069579:Ranibizumab