title: Pd-catalyzed asymmetric allylic alkylation of indoles and pyrroles by chiral alkene-phosphine ligands.
abstract: A variety of chiral binaphthyl-based terminal-alkene-phosphine hybrid ligands were synthesized in four steps with (S)-BINOL as a starting material and utilized for the Pd-catalyzed enantioselective allylic alkylations of indoles and pyrroles to afford the desired products in high yields with good to excellent ee's.
authors.affiliation: Beijing National Laboratory of Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Ziping
authors.initials: Z
authors.lastname: Cao
authors.forename: Yilin
authors.initials: Y
authors.lastname: Liu
authors.forename: Zhaoqun
authors.initials: Z
authors.lastname: Liu
authors.forename: Xiangqing
authors.initials: X
authors.lastname: Feng
authors.forename: Minyang
authors.initials: M
authors.lastname: Zhuang
authors.forename: Haifeng
authors.initials: H
authors.lastname: Du
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000478:Alkylation; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D007211:Indoles; D008024:Ligands; D010720:Phosphines; D011758:Pyrroles; D010165:Palladium; C044646:phosphine