title: [Primary distal renal tubular acidosis: a case report].
abstract: The primary distal renal tubular acidosis is characterized biochemically by the inability of the kidney to produce appropriately acid urine in the presence of systemic metabolic acidosis or after acid loading (e.g. ammonium chloride). It is secondary to defective excretion of H(+) by the cells of the collecting duct. We report the observation of the child MC, 4-year-old, for whom the association of polyuria-polydipsia syndrome, a failure to thrive, nephrolithiasis, hypercalciuria, and especially a high urine pH in the presence of metabolic acidosis did evoke diagnosis of distal renal tubular acidosis. An urine acidification test with ammonium chloride was performed, the urinary pH was always higher than 5.5, thus confirming the diagnosis.
authors.affiliation: Laboratoire de Biochimie, Unité de Recherche, Faculté de Médecine, Sousse, Tunisie.
authors.forename: Jihene Ben
authors.initials: JB
authors.lastname: Abdallah
authors.forename: Bassem
authors.initials: B
authors.lastname: Charfeddine
authors.forename: Imen
authors.initials: I
authors.lastname: Braham
authors.forename: Souhir
authors.initials: S
authors.lastname: Neffati
authors.forename: Leila Ben
authors.initials: LB
authors.lastname: Othmen
authors.forename: Affef
authors.initials: A
authors.lastname: Letaief
authors.forename: Mohamed Ali
authors.initials: MA
authors.lastname: Smach
authors.forename: Zoheier
authors.initials: Z
authors.lastname: Bourfifa
authors.forename: Hedi
authors.initials: H
authors.lastname: Dridi
authors.forename: Khalifa
authors.initials: K
authors.lastname: Limem
mesh_terms: D000141:Acidosis, Renal Tubular / Q000175:diagnosis; D002675:Child, Preschool; D006801:Humans; D008297:Male