title: A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation.
abstract: A facile and general label-free assay for sensitive and selective DNA detection has been developed based on enzyme amplification and ligand-responsive quadruplex formation.
authors.affiliation: Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
authors.forename: Chuanqi
authors.initials: C
authors.lastname: Zhao
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D015342:DNA Probes / Q000378:metabolism; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D054856:G-Quadruplexes; D008024:Ligands; D008652:Mesoporphyrins / Q000378:metabolism; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D013050:Spectrometry, Fluorescence
chemical_list: D015342:DNA Probes; D008024:Ligands; D008652:Mesoporphyrins; C065420:N-methylmesoporphyrin IX; D004247:DNA; D005090:Exodeoxyribonucleases; C020133:exodeoxyribonuclease III