title: Gender differences in acute stroke: Istanbul medical school stroke registry.
abstract: BACKGROUND
  We aimed to investigate gender differences in Turkish stroke patients.
  
  
  METHODS
  Demographics, risk factors, clinical and etiologic subtypes, laboratory findings, clinical course, and in-hospital prognosis of 1 522 patients with ischemic stroke (IS) and 320 patients with intracerebral hemorrhage prospectively registered in the Istanbul Medical School Stroke Registry (1994-2004) were analyzed separately.
  
  
  RESULTS
  The mean age of IS patients was higher in females (n : 751) (P<0.0001). In males, smoking, ischemic heart disease, peripheral arterial disease, posterior circulation syndromes, and strokes due to large-artery atherosclerosis were more common (P<0.0001 for each). Prestroke disability, atrial fibrillation (P<0.0001), hypertension (P=0.041), modified Rankin Scale (mRS) 3-5 at admission (P<0.0001), total anterior circulation syndrome (P<0.0001), and cardioembolic stroke (P<0.0001) were more frequent in females. Female gender was an independent predictor of poor outcome (mRS 3-6).
  
  
  CONCLUSIONS
  Gender differences were observed exclusively in patients with IS. Although our patients were younger than those reported, gender differences were similar.
authors.affiliation: Department of Neurology, Istanbul University, Istanbul Medical School, Edip Aktin Stroke Unit, Capa, Istanbul, Turkey. nilufereyes@yahoo.com
authors.forename: Nil Fer
authors.initials: NF
authors.lastname: Yesilot
authors.forename: Bahar Aksay
authors.initials: BA
authors.lastname: Koyuncu
authors.forename: Oguzhan
authors.initials: O
authors.lastname: Coban
authors.forename: Rezzan
authors.initials: R
authors.lastname: Tuncay
authors.forename: Sara Zarko
authors.initials: SZ
authors.lastname: Bahar
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians'; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries; D012720:Severity of Illness Index; D012737:Sex Factors; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome; D014421:Turkey