title: Characteristics and outcomes of very elderly patients after first hospitalization for heart failure.
abstract: BACKGROUND
  The very elderly (age 80 years and older) with heart failure (HF) is a growing population that is rarely included in clinical trials. The aim of this investigation was to describe the characteristics and outcomes of very elderly patients after a first HF hospitalization.
  
  
  RESULTS
  We identified very elderly patients (age 80 years and older) discharged with HF from the Veteran's Administration National Patient Care Database from 1999 to 2008. Outcomes of interest were death during index admission, 30-day and 1-year mortality, and 30-day all-cause and HF readmissions. We used generalized estimating equations to evaluate outcome differences between age groups within the very elderly cohort (ages 80 to 84, 85 to 89, and 90 and older), adjusting for comorbidities, demographics, and clustering by treatment facility. We identified 21 397 very elderly veterans with a first HF hospitalization during the study period. Thirty-day mortality decreased from 14% to 7% (both P<0.001) and 1-year mortality decreased from 49% to 27% (P<0.001). Although these improvements were most notable for patients age 90 and older (1-year mortality improved by 25.9%), the adjusted odds of death within 1 year were highest for the oldest veterans (odds ratio, 1.85; 95% confidence interval, 1.64 to 2.09, using the 80- to 85-year age group as reference). For all patients, 30-day all-cause readmissions remained largely unchanged and did not differ between age groups.
  
  
  CONCLUSIONS
  Mortality for very elderly HF patients has improved over time, but 30-day readmissions remain frequent. Future studies should identify interventions to reduce cardiac and noncardiac rehospitalization of very elderly HF patients.
authors.affiliation: Stanford University, Palo Alto, CA, USA. rashmee@stanford.edu
authors.forename: Rashmee U
authors.initials: RU
authors.lastname: Shah
authors.forename: Vivian
authors.initials: V
authors.lastname: Tsai
authors.forename: Liviu
authors.initials: L
authors.lastname: Klein
authors.forename: Paul A
authors.initials: PA
authors.lastname: Heidenreich
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006333:Heart Failure / Q000453:epidemiology / Q000401:mortality*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006787:Hospitals, Veterans / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D010359:Patient Readmission / Q000706:statistics & numerical data; D011379:Prognosis; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology