title: Inhibition of cysteine peptidase activity in ascitic fluid in pancreatic cancer patients.
abstract: The work's objective is to answer the question whether there is any possibility of activity inhibition of cysteine peptidases inhibitors playing an important role in key processes accompanying cancer formation, including pancreas. There is a justified speculation that specific inhibitors of these enzymes may inhibit development of cancer processes by inhibiting their activity. In vitro studies confirmed that these enzymes in ascitic fluid were inhibited with egg whites inhibitors even to 90% of their original activity.
authors.affiliation: 2nd Department of General and Oncological Surgery, Medical University of Wrocław, Poland. dranilpreeti@gmail.com
authors.forename: Anil Kumar
authors.initials: AK
authors.lastname: Agrawal
authors.forename: Wojciech
authors.initials: W
authors.lastname: Kielan
authors.forename: Abdo
authors.initials: A
authors.lastname: Katib
authors.forename: Zgmunt
authors.initials: Z
authors.lastname: Grzebieniak
authors.forename: Adam
authors.initials: A
authors.lastname: Skalski
authors.forename: Tomasz
authors.initials: T
authors.lastname: Grzebieniak
authors.forename: Lukasz
authors.initials: L
authors.lastname: Duda-Barcik
authors.forename: Anna
authors.initials: A
authors.lastname: Janocha
authors.forename: Maciej
authors.initials: M
authors.lastname: Siewiński
mesh_terms: D001202:Ascitic Fluid / Q000201:enzymology* / Q000378:metabolism; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D015853:Cysteine Proteinase Inhibitors / Q000494:pharmacology*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000201:enzymology* / Q000378:metabolism
chemical_list: D015853:Cysteine Proteinase Inhibitors; D003546:Cysteine Endopeptidases