title: Current concept of endoscopic ultrasound-guided fine needle aspiration for pancreatic cancer.
abstract: Endoscopic ultrasound (EUS) provides detailed, high-resolution images of the pancreas. However, whether a lesion is malignant or benign cannot be diagnosed solely from its imaging features on EUS. The introduction of EUS-guided fine needle aspiration (EUS-FNA) offers the possibility to obtain a cytological or histological diagnosis of pancreatic lesions with a high sensitivity and specificity. Although the clinical utility of EUS-FNA for pancreatic diseases is widely accepted, the indication for preoperative tissue diagnosis of pancreatic lesions suspected to be malignant is still controversial. This review highlights the diagnostic potential of EUS-FNA, as well as its current indications and contraindications, complications, and techniques.
authors.affiliation: Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan. nobumasa @ aichi-cc.jp
authors.forename: Nobumasa
authors.initials: N
authors.lastname: Mizuno
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hara
authors.forename: Susumu
authors.initials: S
authors.lastname: Hijioka
authors.forename: Vikram
authors.initials: V
authors.lastname: Bhatia
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yatabe
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamao
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging; D001327:Autoimmune Diseases / Q000000981:diagnostic imaging; D044963:Biopsy, Fine-Needle / Q000009:adverse effects / Q000379:methods*; D000075202:Contraindications; D019160:Endosonography / Q000009:adverse effects / Q000379:methods; D006801:Humans; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging; D010179:Pancreas / Q000000981:diagnostic imaging* / Q000473:pathology; D010181:Pancreatic Cyst / Q000000981:diagnostic imaging; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D010195:Pancreatitis / Q000000981:diagnostic imaging