title: [A case of primary lung cancer with swollen mediastinal lymph nodes due to pre-existing sarcoidosis].
abstract: A 69-year-old man, who had been followed up for sarcoidosis at another hospital from 10 years previously, was referred to our hospital because of a new lesion in the left upper lobe. A chest CT scan revealed a nodular lesion at the orifice of the left B3b and mediastinal lymphadenopathy. Bronchoscopic biopsy established a diagnosis of squamous cell carcinoma. Because there had been no distant metastasis and no change in size of the mediastinal lymph nodes over the previous 5 years, left upper lobectomy with lymph node dissection was performed. The histology of the resected tumor indicated a moderately-differentiated squamous cell carcinoma, and the dissected lymph nodes contained non-caseous epithelioid cell granuloma without metastasis. Thus, we made a final diagnosis of squamous cell carcinoma (pT1N0M0, stage IA) that complicated the sarcoidosis. Surgical resection can be the first option for lung cancer complicating sarcoidosis with mediastinal lymphadenopathy, because making a preoperative assessment of N status is difficult.
authors.affiliation: Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Mimura
authors.forename: Yoshirou
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Nakahara
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Kawamura
authors.forename: Shin
authors.initials: S
authors.lastname: Sasaki
authors.forename: Rinko
authors.initials: R
authors.lastname: Katsuda
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000601:surgery; D008206:Lymphatic Diseases / Q000473:pathology*; D008297:Male; D008482:Mediastinum; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000473:pathology*