title: [Collagen-binding activity of Willebrand factor and thrombocyte aggregation in patients with frostbite].
abstract: In the article was quoted data about the thrombocyte aggregation and collagenbinding activity of Willebrand factor in the blood of 50 patients with local frostbite of third and forth degree. Thrombocyte aggregation was studied with the help of photometry. Collagenbinding activity of Willebrand factor was determined with the help of enzyme-linked immunosorbent assay. It was established that decrease of intensity, potential and rate of induced thrombocyte aggregation took place in patients. Collagenbinding activity of Willebrand factor in blood plasma increase in 1, 7-2, 6 times.
authors.forename: K G
authors.initials: KG
authors.lastname: Shapovalov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Vitkovskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D003094:Collagen / Q000378:metabolism*; D004837:Epinephrine / Q000494:pharmacology; D005627:Frostbite / Q000097:blood*; D006801:Humans; D035002:Lower Extremity / Q000293:injuries; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D011485:Protein Binding; D013997:Time Factors; D015599:Trauma Severity Indices; D034941:Upper Extremity / Q000293:injuries; D014945:Wound Healing; D055815:Young Adult; D014841:von Willebrand Factor / Q000378:metabolism*
chemical_list: D014841:von Willebrand Factor; D003094:Collagen; D004837:Epinephrine