title: Reaction of arynes with amino acid esters.
abstract: An efficient route to a variety of 2-phenylindolin-3-ones from amino acid methyl esters has been developed. The reaction of amino acid methyl esters with benzyne prepared from 2-(trimethylsilyl)phenyl triflate and CsF gave 2-phenylindolin-3-ones in moderate to good yields.
authors.affiliation: Department of Chemistry, Faculty of Science, Fukuoka University, Fukuoka 814-0180, Japan. kokuma@fukuoka-u.ac.jp
authors.forename: Kentaro
authors.initials: K
authors.lastname: Okuma
authors.forename: Nahoko
authors.initials: N
authors.lastname: Matsunaga
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Nagahora
authors.forename: Kosei
authors.initials: K
authors.lastname: Shioji
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Yokomori
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004952:Esters; D007211:Indoles / Q000737:chemistry; D008968:Molecular Conformation
chemical_list: D000596:Amino Acids; D004952:Esters; D007211:Indoles; C542223:2-phenylindole