title: Shoenfeld's syndrome after pandemic influenza A/H1N1 vaccination.
abstract: Recently, reports have suggested grouping different autoimmune conditions that are triggered by external stimuli as a single syndrome called autoimmune/inflammatory syndrome induced by adjuvants (ASIA). This syndrome is characterized by the appearance of myalgia, myositis, muscle weakness, arthralgia, arthritis, chronic fatigue, sleep disturbances, cognitive impairment and memory loss, and the possible emergence of a demyelinating autoimmune disease caused by systemic exposure after vaccines and adjuvants. In the current study, the authors reported the first Brazilian case of a woman who developed ASIA, which was characterized by arthralgia, changes in inflammatory markers, and chronic fatigue, after the pandemic anti-influenza A/H1N1 vaccine without causing any other rheumatic disease, and it had a positive outcome.
authors.affiliation: Rheumatology Division, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
authors.forename: S M
authors.initials: SM
authors.lastname: Barros
authors.forename: J F
authors.initials: JF
authors.lastname: Carvalho
mesh_terms: D000277:Adjuvants, Pharmaceutic / Q000009:adverse effects*; D000328:Adult; D001327:Autoimmune Diseases / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000139:chemically induced*; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000009:adverse effects*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control; D058873:Pandemics; D013577:Syndrome
chemical_list: D000277:Adjuvants, Pharmaceutic; D007252:Influenza Vaccines