title: Ingestions of hydrocodone, carisoprodol, and alprazolam in combination reported to Texas poison centers.
abstract: The combination of hydrocodone, carisoprodol, and alprazolam is subject to abuse. Ingestions of this drug combination reported to Texas poison centers during 1998-2009 were identified (totaling 1,295 cases) and the distribution of ingestions by selected factors was determined. The number of cases increased from 0 in 1998 to 200 in 2007, and then decreased to 132 in 2009. The counties in eastern and southeastern Texas accounted for 80.9% of the cases. Of the patients, 57.3% were women and 94.6% were age 20 or older. Suspected attempted suicide accounted for 59.3% of the cases and intentional misuse or abuse for 27.3%.
authors.affiliation: Environmental Epidemiology and Disease Registries Section, Texas Department of State Health Services, 1100 W 49th Street, Austin, TX 78756, USA. mathias.forrester@dshs.state.tx.us
authors.forename: Mathias B
authors.initials: MB
authors.lastname: Forrester
mesh_terms: D000328:Adult; D000368:Aged; D000525:Alprazolam / Q000008:administration & dosage / Q000506:poisoning*; D002328:Carisoprodol / Q000008:administration & dosage / Q000506:poisoning*; D003128:Coma / Q000139:chemically induced; D004338:Drug Combinations; D004435:Eating; D005260:Female; D006801:Humans; D006853:Hydrocodone / Q000008:administration & dosage / Q000506:poisoning*; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000008:administration & dosage / Q000506:poisoning*; D009294:Narcotics / Q000008:administration & dosage / Q000506:poisoning*; D011039:Poison Control Centers / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013781:Texas / Q000453:epidemiology; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D006993:Hypnotics and Sedatives; D009125:Muscle Relaxants, Central; D009294:Narcotics; D002328:Carisoprodol; D006853:Hydrocodone; D000525:Alprazolam