title: Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts.
abstract: Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Mengchun
authors.initials: M
authors.lastname: Ye
authors.forename: Guo-Lin
authors.initials: GL
authors.lastname: Gao
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D010165:Palladium / Q000737:chemistry*; D010618:Phenanthrolines / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
chemical_list: D000475:Alkenes; D008024:Ligands; D010618:Phenanthrolines; D011725:Pyridines; D010165:Palladium; C025205:1,10-phenanthroline