title: Impact of spontaneous smoking cessation on sperm quality: case report.
abstract: We evaluated sperm quality after a 3-month smoking cessation programme by sperm analysis, objective sperm motility analysis, protein tyrosine phosphorylation in capacitating conditions and DNA fragmentation (TUNEL). Sperm analysis after smoking cessation revealed a distinctive improvement in sperm concentration, fast spermatozoa (≥35 μm/s), sperm vitality, percentage of spermatozoa recuperated after an enrichment technique and protein tyrosine phosphorylation. However, no changes were observed in the number of germinal cells in the ejaculate, sperm morphology and sperm DNA fragmentation. It is concluded that physicians should strongly advise their patients to quit smoking before undergoing medical treatment or assisted reproduction techniques to achieve pregnancy.
authors.affiliation: Laboratory of Andrology and Male Fertility, Clinical Hospital, INFIBIOC, University of Buenos Aires, Argentina.
authors.forename: E
authors.initials: E
authors.lastname: Prentki Santos
authors.forename: S
authors.initials: S
authors.lastname: López-Costa
authors.forename: P
authors.initials: P
authors.lastname: Chenlo
authors.forename: M N
authors.initials: MN
authors.lastname: Pugliese
authors.forename: S
authors.initials: S
authors.lastname: Curi
authors.forename: J
authors.initials: J
authors.lastname: Ariagno
authors.forename: H
authors.initials: H
authors.lastname: Repetto
authors.forename: M
authors.initials: M
authors.lastname: Sardi
authors.forename: L
authors.initials: L
authors.lastname: Palaoro
authors.forename: G
authors.initials: G
authors.lastname: Mendeluk
mesh_terms: D005260:Female; D005306:Fertilization; D006801:Humans; D007150:Immunohistochemistry; D020287:In Situ Nick-End Labeling; D008297:Male; D008875:Middle Aged; D010766:Phosphorylation; D011247:Pregnancy; D018873:Pregnancy Rate; D016540:Smoking Cessation; D013094:Spermatozoa / Q000502:physiology*; D014443:Tyrosine / Q000378:metabolism
chemical_list: D014443:Tyrosine