title: Normal neuroimaging in early-onset Krabbe disease.
abstract: Krabbe disease has characteristic findings on brain magnetic resonance imaging (MRI) according to age of clinical onset. MRI-negative Krabbe disease has not been reported in early-onset cases. We present the serial clinical and MRI of brain findings in a case of early-onset Krabbe disease with proven enzyme deficiency. Despite clinical progression, the MRI findings of the child remained normal over a period of 15 months.
authors.affiliation: Department of Pediatrics (Pediatric Neurology Division), K. L. E. University's J. N. Medical College, Belgaum, Karnataka State, India. drmaheshkamate@gmail.com
authors.forename: Mahesh
authors.initials: M
authors.lastname: Kamate
authors.forename: Virupaxi
authors.initials: V
authors.lastname: Hattiholi
mesh_terms: D001921:Brain / Q000473:pathology*; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007965:Leukodystrophy, Globoid Cell / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*