title: Peptide toxin components of Amanita exitialis basidiocarps.
abstract: Eight peptide toxins were isolated and purified from basidiocarps of Amanita exitialis with high performance liquid chromatography and were subjected to ultraviolet, nuclear magnetic resonance and mass spectrometry. We identified seven peptide toxins, α-amanitin, β-amanitin, amaninamide, phallacin, phallacidin, phallisacin and desoxoviroidin. The molecular weight (729.5 Da) of the eighth compound did not match that of any reported Amanita toxins and, although the UV absorption spectrum indicated it to be a phallotoxin, further studies are required to identify this component. This is the first report of amaninamide, phallacin, phallisacin and desoxoviroidin in this lethal mushroom species.
authors.affiliation: Guangdong Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangdong Guangzhou, China.
authors.forename: Wang-Qiu
authors.initials: WQ
authors.lastname: Deng
authors.forename: Tai-Hui
authors.initials: TH
authors.lastname: Li
authors.forename: Ping-Gen
authors.initials: PG
authors.lastname: Xi
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Gan
authors.forename: Zheng-Duan
authors.initials: ZD
authors.lastname: Xiao
authors.forename: Zi-De
authors.initials: ZD
authors.lastname: Jiang
mesh_terms: D000545:Amanita / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D013058:Mass Spectrometry; D009183:Mycotoxins / Q000737:chemistry* / Q000302:isolation & purification*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry / Q000302:isolation & purification; D013056:Spectrophotometry, Ultraviolet
chemical_list: D009183:Mycotoxins; D010455:Peptides