title: [The effect of hyperbaric oxygen therapy on treatment of late healed wounds after pharyngeal and laryngeal surgery].
abstract: OBJECTIVE
  To investigate effect of hyperbaric oxygen (HBO) therapy on treatment of late healed wounds after pharyngeal and laryngeal carcinomas surgery.
  
  
  METHODS
  Eighty-three patients with late healed wounds after pharyngolaryngectomy were divided into two groups, which were HBO treatment group (n = 48) and control group (n = 35) by random. 48 cases were treated with the general therapeutic measure along with HBO (the pressure is 2 x 10(5) Pa, 110 minutes per day for 5 to 10 days). The other 35 cases were treated with the general therapy without HBO as control.
  
  
  RESULTS
  There were fresh granulation erupted from the wound of entry after 3 or 4 days of HBO) treatment, then the granulation and the new blood capillary erupted continually to fill the wound surface, and the wound of entry was healed over finally. In the HBO and the control groups, the average healing time was 27.50 and 45.00 days (P < 0.01) in the wound by necrosectomy of the myocutaneous flap or forearm flap, 8. 50 and 14.09 days (P < 0.01) in the pharyngeal fistula, 5.93 and 8.62 days (P < 0.01) in the infected or fluid-filled wound.
  
  
  CONCLUSIONS
  HBO therapy is an effective and powerful treatment for late healed postoperative wounds in pharyngeal and laryngeal carcinomas surgery.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Affiliated Hospital of Medical College Qingdao University, Qingdao, 266003, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Jiang
authors.forename: Dapeng
authors.initials: D
authors.lastname: Liang
authors.forename: Haiqin
authors.initials: H
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Shang
authors.forename: Peisong
authors.initials: P
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D007822:Laryngeal Neoplasms / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures; D011184:Postoperative Period; D016896:Treatment Outcome; D014945:Wound Healing