title: [Effect of celleks on functional and morphological changes in experimental focal ischemia of prefrontal areas of the rat brain cortex].
abstract: The effect of the new original drug celleks on the functional CNS activity and volume of ischemic damage has been studied in the experimental model of photochemically induced bilateral thrombosis of the prefrontal cortex. The chronic (once a day during 4 days) and even single (one hour after the operation) treatment of rats with celleks (intraperitoneal, 3 mg/kg) after the cortical photothrombosis resulted in the restoration of passive avoidance and diminishing of the volume of ischemic damage.
authors.forename: G A
authors.initials: GA
authors.lastname: Romanova
authors.forename: F M
authors.initials: FM
authors.lastname: Shakova
authors.forename: I V
authors.initials: IV
authors.lastname: Barskov
authors.forename: E V
authors.initials: EV
authors.lastname: Stel'mashuk
authors.forename: T V
authors.initials: TV
authors.lastname: Petrov
authors.forename: M A
authors.initials: MA
authors.lastname: Sokolov
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D003214:Conditioning, Classical / Q000187:drug effects; D004195:Disease Models, Animal; D004334:Drug Administration Schedule; D007274:Injections, Intraperitoneal; D008297:Male; D009414:Nerve Growth Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017397:Prefrontal Cortex / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D051381:Rats; D016896:Treatment Outcome
chemical_list: D009414:Nerve Growth Factors; D018696:Neuroprotective Agents