title: [Incidence and characteristics of bronchial colonisation in patient with lung cancer: a retrospective study of 388 cases].
abstract: BACKGROUND
  Bronchial colonisation is frequently reported in patients with lung cancer. These colonisations could influence patient therapeutic management and prognosis. The aim of our study is refine incidence and nature of bronchial colonisations in patients presenting with lung cancer.
  
  
  METHODS
  Three hundred and eighty-eight patients with lung cancer underwent a flexible bronchoscopy at the time of diagnosis. Among them, 216 patients had a bacteriological, mycobacteriological and fungal investigation. Type and frequency of these colonisations were analyzed.
  
  
  RESULTS
  Potential pathogens were found in 39.8% of samples, including mainly 39.8% of Gram-negative bacilli (Haemophilus influenzae, Enterobacter sp., Escherichia coli). In addition, we found 0.9% of mycobacteria and 13.9% of Candida albicans. Among these 216 patients where microbiological analysis was performed, patient features and tumor stage were not significantly correlated to microbial colonisation.
  
  
  CONCLUSIONS
  Colonisation of airways is frequently reported when a lung cancer is diagnosed. Our data suggest that bronchial colonisation should be prospectively collected due to its potential interest in the management of lung cancer patients.
authors.affiliation: Service de pneumologie, clinique des voies respiratoires, hôpital Larrey, CHU de Toulouse, 24 chemin de Pouvourville, Toulouse cedex 09, France.
authors.forename: S
authors.initials: S
authors.lastname: Laroumagne
authors.forename: A
authors.initials: A
authors.lastname: Salinas-Pineda
authors.forename: C
authors.initials: C
authors.lastname: Hermant
authors.forename: M
authors.initials: M
authors.lastname: Murris
authors.forename: P-A
authors.initials: PA
authors.lastname: Gourraud
authors.forename: C
authors.initials: C
authors.lastname: Do
authors.forename: C
authors.initials: C
authors.lastname: Segonds
authors.forename: A
authors.initials: A
authors.lastname: Didier
authors.forename: J
authors.initials: J
authors.lastname: Mazières
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D001980:Bronchi / Q000382:microbiology*; D001991:Bronchitis / Q000382:microbiology*; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology*; D001999:Bronchoscopy; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000150:complications; D005260:Female; D005602:France / Q000453:epidemiology; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000150:complications* / Q000453:epidemiology; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects