title: Inducible Clindamycin Resistance among Staphylococci Isolated from Burn Patients.
abstract: Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 66.2% of 65 methicillin-resistant S. aureus isolates and in none of 55 methicillin-sensitive S. aureus, 10 methicillin-resistant coagulase negative staphylococci and 29 methicllin-sensitive coagulase negative staphylococci isolates. In our setting, clindamycin can be used for the treatment of infections due to staphylococci, but we recommend that staphylococci isolates, particularly methicillin-resistant S. aureus, are tested by the D-test before treatment.
authors.affiliation: Department of Microbiology and Immunology, Faculty of Medicine, El-Fateh University for Medical Sciences.
authors.forename: A
authors.initials: A
authors.lastname: Zorgani
authors.forename: O
authors.initials: O
authors.lastname: Shawerf
authors.forename: K
authors.initials: K
authors.lastname: Tawil
authors.forename: E
authors.initials: E
authors.lastname: El-Turki
authors.forename: Ks
authors.initials: K
authors.lastname: Ghenghesh