title: Venous thromboembolic events following foot and ankle surgery in the English National Health Service.
abstract: Diagnostic and operative codes are routinely collected for every patient admitted to hospital in the English NHS. Data on post-operative complications following foot and ankle surgery have not previously been available in large numbers. Data on symptomatic venous thromboembolism events and mortality within 90 days were extracted for patients undergoing fixation of an ankle fracture, first metatarsal osteotomy, hindfoot fusions and total ankle replacement over a period of 42 months. For ankle fracture surgery (45 949 patients), the rates of deep-vein thrombosis (DVT), pulmonary embolism and mortality were 0.12%, 0.17% and 0.37%, respectively. For first metatarsal osteotomy (33 626 patients), DVT, pulmonary embolism and mortality rates were 0.01%, 0.02% and 0.04%, and for hindfoot fusions (7033 patients) the rates were 0.03%, 0.11% and 0.11%, respectively. The rate of pulmonary embolism in 1633 total ankle replacement patients was 0.06%, and there were no recorded DVTs and no deaths. Statistical analysis could only identify risk factors for venous thromboembolic events of increasing age and multiple comorbidities following fracture surgery. Venous thromboembolism following foot and ankle surgery is extremely rare, but this subset of fracture patients is at a higher risk. However, there is no evidence that thromboprophylaxis reduces this risk, and these national data suggest that prophylaxis is not required in most of these patients.
authors.affiliation: Northumbria Healthcare NHS Foundation Trust, Woodhorn Lane, Ashington, Northumberland NE63 9JJ, UK. simonjameson@doctors.org.uk
authors.forename: S S
authors.initials: SS
authors.lastname: Jameson
authors.forename: A
authors.initials: A
authors.lastname: Augustine
authors.forename: P
authors.initials: P
authors.lastname: James
authors.forename: I
authors.initials: I
authors.lastname: Serrano-Pedraza
authors.forename: K
authors.initials: K
authors.lastname: Oliver
authors.forename: D
authors.initials: D
authors.lastname: Townshend
authors.forename: M R
authors.initials: MR
authors.lastname: Reed
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000842:Ankle / Q000601:surgery*; D000925:Anticoagulants / Q000627:therapeutic use*; D004739:England; D005260:Female; D005528:Foot / Q000601:surgery*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D018570:Risk Assessment; D012307:Risk Factors; D013222:State Medicine; D054556:Venous Thromboembolism / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D006493:Heparin