title: [Ocular masquerade syndrome in a patient with chronic lymphocytic leukemia].
abstract: OBJECTIVE
  To report a rare case of a masquerading syndrome in a course of chronic lymphocytic leukemia (CLL).
  
  
  METHODS
  A 57 years old woman with bilateral lacrimal glands enlargement and chronic uveitis unresponsive to local steroids, was studied. Patient's general history was positive for chronic lymphocytic leukemia, B cell (B-CLL); actually remission. The patient underwent complete ophthalmic examination with additional A and B-scan ultrasonography (USG), computed tomography (CT) and nuclear magnetic resonance (NMR) imaging of orbital cavities and also biopsy of both lacrimal glands was performed.
  
  
  RESULTS
  USG, CT and NMR scans revealed the intraocular inflammation and inflammatory enlargement of both lacrimal glands. The histopathological examination of lacrimal glands showed the presence of lymphocytic infiltrations within the glands' tissue. The patient started with chemotherapy: Fludarabin and Cyclophosphamide. Within weeks the intraocular inflammation was under control and the resolution of lacrimal glands edema was noted.
  
  
  CONCLUSIONS
  Malignancy should be considered in cases of chronic uveitis that do not respond to steroid therapy. Chronic lymphocytic leukemia rarely masks as chronic intraocular inflammation, in a sporadic cases however it may herald the relapse of the disease.
authors.affiliation: Z Kliniki Okulistyki i Onkologii Okulistycznej Katedry Okulistyki, Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kubicka-Trzaska
authors.forename: Monika
authors.initials: M
authors.lastname: Gedliczka
authors.forename: Bozena
authors.initials: B
authors.lastname: Romanowska-Dixon
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D004487:Edema / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D013577:Syndrome; D016896:Treatment Outcome; D014605:Uveitis / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D014786:Vision Disorders / Q000188:drug therapy / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents