title: The contribution of rapid intraoperative cytology in the evaluation of endometrial cancer spread.
abstract: BACKGROUND
  Peritoneal washing cytology and imprint cytology of pelvic lymph nodes samples were used to evaluate the rapid cytologic detection of peritoneal and retroperitoneal spread of endometrial cancer.
  
  
  METHODS
  We undertook a study on 194 endometrial cancer patients who underwent primary treatment in the Gynecologic Clinic, Democritus University of Thrace. All patients were subjected to peritoneal washing (PW) cytology and imprint cytology performed on lymph node sampling. The cytologic specimens were stained by May-Grünwald Giemsa (MGG) and Haematoxylin eosin (HE) techniques. Cell-blocks prepared from peritoneal washings (PWs) and the lymph node samples were sent for histologic examination. The cytologic fi ndings were correlated to histologic results.
  
  
  RESULTS
  Rapid intraoperative cytology provides a useful diagnostic technique for the assessment of endometrial cancer spread. HE and MGG stain presented different values of sensitivity and specifi city in the detection of peritoneal and retroperitoneal spread of endometrial cancer.
  
  
  CONCLUSIONS
  Cytologic assessment of intraperitoneal and retroperitoneal spread of endometrial cancer is a rapid, intraoperative procedure, which provides the surgeon with useful information regarding the stage of the disease and the subsequent therapeutic approach.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Anastasiadis
authors.forename: Nikoleta
authors.initials: N
authors.lastname: Koutlaki
authors.forename: Vasilios
authors.initials: V
authors.lastname: Liberis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Tsikouras
authors.forename: Marina
authors.initials: M
authors.lastname: Dimitraki
authors.forename: Anastasios
authors.initials: A
authors.lastname: Liberis
authors.forename: George
authors.initials: G
authors.lastname: Galazios
mesh_terms: D003581:Cytodiagnosis; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology*; D004801:Eosine Yellowish-(YS); D005260:Female; D006115:Greece; D006801:Humans; D007432:Intraoperative Period; D008198:Lymph Nodes / Q000166:cytology / Q000473:pathology; D008751:Methylene Blue; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D010537:Peritoneum / Q000166:cytology* / Q000473:pathology; D013997:Time Factors
chemical_list: C043260:May-Grunwald Giemsa; D008751:Methylene Blue; D004801:Eosine Yellowish-(YS)