title: Cytotoxic and genotoxic impact of TiO2 nanoparticles on A549 cells.
abstract: Titania nanoparticles are produced by tons, and included in commercial products, raising concerns about their potential impact on human health. This study relates their cytotoxic and genotoxic impact on a cell line representative of human lung, namely A549 alveolar epithelial cells.
authors.affiliation: IRAMIS/Laboratoire de Structure et Dynamique par Résonance Magnétique, UMR 3299 CEA-CNRS, Saclay, France.
authors.forename: M L
authors.initials: ML
authors.lastname: Jugan
authors.forename: S
authors.initials: S
authors.lastname: Barillet
authors.forename: A
authors.initials: A
authors.lastname: Simon-Deckers
authors.forename: S
authors.initials: S
authors.lastname: Sauvaigo
authors.forename: T
authors.initials: T
authors.lastname: Douki
authors.forename: N
authors.initials: N
authors.lastname: Herlin
authors.forename: M
authors.initials: M
authors.lastname: Carrière
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003603:Cytotoxins / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology*; D053768:Metal Nanoparticles / Q000633:toxicity*; D009152:Mutagenicity Tests / Q000379:methods*; D009153:Mutagens / Q000633:toxicity; D014025:Titanium / Q000633:toxicity; D023382:Toxicity Tests, Acute / Q000379:methods*
chemical_list: D003603:Cytotoxins; D009153:Mutagens; C009495:titanium dioxide; D014025:Titanium