title: Possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: two case reports.
abstract: In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.
authors.affiliation: Division of Rheumatology, Jichi Medical University Saitama Medical Center, Saitamao, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yabe
authors.forename: Hironori
authors.initials: H
authors.lastname: Ueno
authors.forename: Kensuke
authors.initials: K
authors.lastname: Ochi
authors.forename: Hideo
authors.initials: H
authors.lastname: Morioka
authors.forename: Hiroo
authors.initials: H
authors.lastname: Yabe
authors.forename: Chihiro
authors.initials: C
authors.lastname: Terai