title: Motivators, concerns, and barriers to adoption of preexposure prophylaxis for HIV prevention among gay and bisexual men in HIV-serodiscordant male relationships.
abstract: The purpose of this study was to identify factors that may facilitate or impede future adoption of preexposure prophylaxis (PrEP) for HIV prevention among gay and bisexual men in HIV-serodiscordant relationships. This qualitative study utilized semistructured interviews conducted with a multiracial/-ethnic sample of 25 gay and bisexual HIV-serodiscordant male couples (n=50 individuals) recruited from community settings in Los Angeles, CA. A modified grounded theory approach was employed to identify major themes relating to future adoption of PrEP for HIV prevention. Motivators for adoption included protection against HIV infection, less concern and fear regarding HIV transmission, the opportunity to engage in unprotected sex, and endorsements of PrEP's effectiveness. Concerns and barriers to adoption included the cost of PrEP, short- and long-term side effects, adverse effects of intermittent use or discontinuing PrEP, and accessibility of PrEP. The findings suggest the need for a carefully planned implementation program along with educational and counseling interventions in the dissemination of an effective PrEP agent.
authors.affiliation: Department of Family Medicine, David Geffen School of Medicine, University of California, Los Angeles, USA. rbrooks1@ucla.edu
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Brooks
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Kaplan
authors.forename: Eli
authors.initials: E
authors.lastname: Lieber
authors.forename: Raphael J
authors.initials: RJ
authors.lastname: Landovitz
authors.forename: Sung-Jae
authors.initials: SJ
authors.lastname: Lee
authors.forename: Arleen A
authors.initials: AA
authors.lastname: Leibowitz
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D001727:Bisexuality / Q000523:psychology*; D015658:HIV Infections / Q000517:prevention & control / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D018451:Homosexuality, Male / Q000523:psychology*; D006801:Humans; D015141:Los Angeles; D008297:Male; D008875:Middle Aged; D009042:Motivation; D011292:Premedication / Q000523:psychology*; D036301:Qualitative Research; D012309:Risk-Taking; D012747:Sexual Partners / Q000523:psychology*; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents