title: [Malignant astrocytoma as a recurrance of astrocytoma II WHO after 13 years. Case report and literature review].
abstract: Astrocytomas--neroepithelial originated tumors that belong to the big, differential group of tumors, which derive from astrocytic glial. They include slow growing tumors such as fibillary astrocytoma or very malignant glioblastoma multiforme. The case which is being presented is of a forty nine year old woman operated in July 1997 because of a protoplasmic astrocytoma II WHO in the left frontal lobe. The main symptoms were epilepsy seizures. The patient was operated totally followed by adjuvant radiotherapy. 13 years later epilepsy seizures with syncope showed up again. Due to this adverse event MRI was ordered and suspicion of tumor recurrence was put forward. The lesion was removed radically with a neuronavigation guided technique. Histopathology identified anaplastic astrocytoma III WHO. According to literature, the factors regarding remission time, tumor malignancy and therapeutic aim were analyzed.
authors.affiliation: Klinika Neurochirurgii i Neurochirurgii Dzieciecej Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1, 71-252 Szczecin.
authors.forename: Dominika
authors.initials: D
authors.lastname: Parafiniuk
authors.forename: Dariusz
authors.initials: D
authors.lastname: Jezewski
authors.forename: Przemysław
authors.initials: P
authors.lastname: Nowacki
mesh_terms: D000328:Adult; D001254:Astrocytoma; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D005625:Frontal Lobe; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D012640:Seizures / Q000209:etiology