title: Complications after oral surgery in patients with congenital or drug-induced bleeding disorders.
abstract: BACKGROUND
  Bleeding disorders (BD) can cause significant problems during or after surgical procedures of the oral cavity. The aim of this study was to explore the risk of bleeding following oral surgery in patients with BD.
  
  
  METHODS
  The medical records of all BD patients referred to the department of cranio- and maxillofacial surgery were reviewed.
  
  
  RESULTS
  Ninety-five patients (26 inherent BD, 69 taking antithrombotic drugs) were reviewed for this study. Interestingly, patients taking oral anticoagulants presented more bleeding complications than patients with inherent BD. During simple tooth extraction procedures, patients taking antithrombotic drugs had a higher risk of bleeding than patients with inherent BD.
  
  
  CONCLUSIONS
  The currently available treatment protocols for surgical treatment of dental patients with inherent BD suffice. However, our data indicates that there is still a need for clear guidelines for the treatment of patients taking antithrombotic drugs, especially phenprocoumon.
authors.affiliation: Department for Cranio- and Maxillofacial Surgery of Heinrich Heine University Düsseldorf, Moorenstr. 5 (Geb. 18.73), D-40225 Düsseldorf, Germany. handschel@med.uni-duesseldorf.de
authors.forename: Jörg
authors.initials: J
authors.lastname: Handschel
authors.forename: Christoph
authors.initials: C
authors.lastname: Willamowski
authors.forename: Ralf
authors.initials: R
authors.lastname: Smeets
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Ommerborn
authors.forename: Christian
authors.initials: C
authors.lastname: Naujoks
authors.forename: Norbert R
authors.initials: NR
authors.lastname: Kübler
authors.forename: Rita
authors.initials: R
authors.lastname: Depprich
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006474:Hemorrhagic Disorders / Q000139:chemically induced / Q000150:complications* / Q000235:genetics; D006801:Humans; D008297:Male; D019647:Oral Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000706:statistics & numerical data; D019106:Postoperative Hemorrhage / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000925:Anticoagulants