title: [Breast lesion diagnosis: integrating pathology and radiology].
abstract: Preoperative breast biopsies do not always provide a complete picture of a breast abnormality, especially in the subgroup of breast lesions classified as BI-RADS category 4 ('suspicious'). In such cases correlation with imaging results is mandatory. Sometimes ultrasound is the best modality, as demonstrated here in a 77-year-old patient with an intracystic papillary carcinoma with invasion. At other times mammography is preferred, as we demonstrate in a 50-year-old patient with screen-detected microcalcifications, initially diagnosed as ductal carcinoma in situ of the clinging type, later diagnosed as benign ductal hyperplasia. Finally, in a 45-year old patient with a palpable mass, caused by a grade III ductal carcinoma in situ, successful excision with tumour-free margins was achieved thanks to preoperative MRI.
authors.affiliation: Academisch Medisch Centrum, Amsterdam, the Netherlands. h.m.zonderland@amc.uva.nl
authors.forename: Harmien M
authors.initials: HM
authors.lastname: Zonderland
authors.forename: Marc J
authors.initials: MJ
authors.lastname: van de Vijver
authors.forename: Mike
authors.initials: M
authors.lastname: Visser
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D002114:Calcinosis / Q000175:diagnosis; D002278:Carcinoma in Situ / Q000175:diagnosis; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D011300:Preoperative Care; D016217:Ultrasonography, Mammary