title: Image-enhanced capsule endoscopy based on the diagnosis of vascularity when using a new type of capsule.
abstract: BACKGROUND
  Small-bowel lesions responsible for obscure GI bleeding are often accompanied by vascular abnormalities. Image-enhanced capsule endoscopy could be advantageous in detecting these abnormalities.
  
  
  OBJECTIVE
  To evaluate the image representation performance of the contrast capsule.
  
  
  METHODS
  Feasibility study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Consecutive patients with obscure GI bleeding swallowed the contrast capsule.
  
  
  METHODS
  Image representation performance of the contrast capsule and the appearance of small-bowel lesions in image-enhanced capsule endoscopy.
  
  
  RESULTS
  Twenty patients (16 males and 4 females) underwent capsule endoscopy during the study period. Small-bowel abnormality was detected, including 5 cases of multiple erosions or ulcers, 1 case of Peutz-Jeghers syndrome, and 1 case of angiectasia. The contrast capsule visualized the lesions with high vascularity in a dark green color with a strong color contrast compared with the surrounding normal mucosa, which appeared as a brownish color.
  
  
  CONCLUSIONS
  Small, single-center, nonrandomized study.
  
  
  CONCLUSIONS
  This feasibility study demonstrated the image representation characteristics of the contrast capsule. The diagnostic yield of this technology should be investigated in a future randomized trial.
authors.affiliation: Department of Endoscopy, Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Aihara
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ikeda
authors.forename: Hisao
authors.initials: H
authors.lastname: Tajiri
mesh_terms: D000328:Adult; D000368:Aged; D053704:Capsule Endoscopy / Q000295:instrumentation / Q000379:methods*; D003116:Color; D005240:Feasibility Studies; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods*; D007422:Intestines / Q000098:blood supply; D008027:Light; D008297:Male; D008875:Middle Aged; D013270:Stomach / Q000098:blood supply