title: Organocatalytic trifluoromethylation of imines using phase-transfer catalysis with phenoxides. A general platform for catalytic additions of organosilanes to imines.
abstract: A new approach to additions of silicon nucleophiles to imines was developed. The method is based on the phase-transfer of phenoxides by ammonium catalysts, overcoming the inability of amide adducts in promoting the reactions.
authors.affiliation: Department of Organic Chemistry A. Mangini, University of Bologna, V. Risorgimento 4, 40136 Bologna, Italy. luca.bernardi2@.unibo.it
authors.forename: Luca
authors.initials: L
authors.lastname: Bernardi
authors.forename: Eugenio
authors.initials: E
authors.lastname: Indrigo
authors.forename: Salvatore
authors.initials: S
authors.lastname: Pollicino
authors.forename: Alfredo
authors.initials: A
authors.lastname: Ricci
mesh_terms: D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D044367:Phase Transition; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*
chemical_list: D000588:Amines; D006845:Hydrocarbons, Fluorinated; D007097:Imines; D017646:Organosilicon Compounds; D010087:Oxides; D000644:Quaternary Ammonium Compounds