title: [Variation and clinical significance of serum CTnT and CK-MB in patients with acute organophosphorus pesticid poisoning].
abstract: OBJECTIVE
  to explore the variation and clinical significance of serum CTnT and CK-MB in patients with acute organophosphorus pesticid poisoning (AOPP).
  
  
  METHODS
  100 cases of patients with AOPP(AOPP-group) and 100 healthy subjects were studied, the serum CTnT and CK-MB level were detected using ELISA and immunosuppression methods.
  
  
  RESULTS
  after poisoning 6 h, 24h, 72h, the serum CTnT and CK-MB levels of the AOPP group were higher than the controls group, compared difference was significant (P<0.05); The serum CTnT and CK-MB levels increased with increasing degrees of poisoning, the different degrees of poisoning was positively correlated with CTnT and CK-MB levels (r=0.569, 0.498, P<0.01).
  
  
  CONCLUSIONS
  combined monitoring of serum CTnT and CK-MB of AOPP patients can help determine the extend of poisoning, when the serum CTnT and CK-MB levels of the AOPP group increased, the degrees of heart damage is serious, which is important diagnostic significance for heart damage.
authors.affiliation: Department of Emergenc, Tangshan Workers Hospital, Tangshan 063000, China.
authors.forename: Zhi-xiang
authors.initials: ZX
authors.lastname: Wanf
authors.forename: Chun-xia
authors.initials: CX
authors.lastname: Wang
authors.forename: Shuan-hu
authors.initials: SH
authors.lastname: Liu
authors.forename: Ji-hong
authors.initials: JH
authors.lastname: Shi
authors.forename: Yan-yang
authors.initials: YY
authors.lastname: Tu
mesh_terms: D000208:Acute Disease; D000328:Adult; D052279:Creatine Kinase, MB Form / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D008297:Male; D062025:Organophosphate Poisoning; D010575:Pesticides / Q000506:poisoning*; D011041:Poisoning / Q000097:blood / Q000201:enzymology; D020107:Troponin T / Q000097:blood*
chemical_list: D010575:Pesticides; D020107:Troponin T; D052279:Creatine Kinase, MB Form