title: Safety assessment of nanoparticles cytotoxicity and genotoxicity of metal nanoparticles in vitro.
abstract: There is an urgent need to investigate the mechanisms of action of NMs and to develop testing strategies to assess potential environmental and human hazard. Our study has shown that metal nanoparticles such as iron oxide may induce genotoxic effect. It was inferred that coating and surface properties influence NPs cytotoxicity and genotoxicity.
authors.affiliation: Health Effects Group, Norwegian Institute for Air Research (NILU), Instituttvn. 18, N-2027 Kjeller, Norway.
authors.forename: Magdolenova
authors.initials: M
authors.lastname: Zuzana
authors.forename: Rinna
authors.initials: R
authors.lastname: Alessandra
authors.forename: Fjellsbø
authors.initials: F
authors.lastname: Lise
authors.forename: Dusinska
authors.initials: D
authors.lastname: Maria
mesh_terms: D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D003603:Cytotoxins / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D005290:Ferric Compounds / Q000633:toxicity; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D053768:Metal Nanoparticles / Q000633:toxicity*; D009152:Mutagenicity Tests / Q000379:methods*; D009153:Mutagens / Q000633:toxicity; D023382:Toxicity Tests, Acute / Q000379:methods*
chemical_list: D003603:Cytotoxins; D005290:Ferric Compounds; D009153:Mutagens; C000499:ferric oxide