title: Severe infection with Clostridium difficile PCR ribotype 027 acquired in Melbourne, Australia.
abstract: We report the first recognised case of infection with Clostridium difficile PCR ribotype 027 acquired in Australia. This pathogen has caused significant morbidity and mortality in widespread hospital-based outbreaks in the northern hemisphere. Clinicians need to be aware of the clinical picture, limitations of diagnostic tests, availability of further testing for epidemic strains, new therapeutic approaches, and in-hospital control strategies for this infection.
authors.affiliation: Victorian Infectious Disease Service, Royal Melbourne Hospital, Melbourne, VIC, Australia. Michael.Richards@mh.org.au
authors.forename: Michael
authors.initials: M
authors.lastname: Richards
authors.forename: James
authors.initials: J
authors.lastname: Knox
authors.forename: Briony
authors.initials: B
authors.lastname: Elliott
authors.forename: Kate
authors.initials: K
authors.lastname: Mackin
authors.forename: Dena
authors.initials: D
authors.lastname: Lyras
authors.forename: Lynette J
authors.initials: LJ
authors.lastname: Waring
authors.forename: Thomas V
authors.initials: TV
authors.lastname: Riley
mesh_terms: D000369:Aged, 80 and over; D001315:Australia / Q000453:epidemiology; D016360:Clostridioides difficile; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects; D006801:Humans; D008297:Male