title: Fatal bile duct necrosis: a rare complication of transcatheter arterial chemoembolization in a patient with endocrine hepatic metastasis.
abstract: We report the first case of fatal bile duct necrosis following transcatheter arterial chemoembolization (TACE) in a 58-year-old woman. The patient underwent two TACEs to treat hepatic metastases from an ileal endocrine tumor. Persistent cholestasis occurred after the second procedure, leading to the diagnosis of bile duct necrosis confirmed by liver biopsy. The patient died of liver failure with encephalopathy six months after the second TACE. Even though this complication is very rare, physicians should consider this diagnosis in patients who develop chronic, marked cholestasis following a TACE procedure.
authors.affiliation: Pôle des Maladies de l'Appareil Digestif, Service de Gastroentérologie-Pancréatologie, Clichy, France.
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Pelletier
authors.forename: Pascal
authors.initials: P
authors.lastname: Hammel
authors.forename: Magali
authors.initials: M
authors.lastname: Zappa
authors.forename: Pierre
authors.initials: P
authors.lastname: Bedossa
authors.forename: Vinciane
authors.initials: V
authors.lastname: Rebours
authors.forename: Olivia
authors.initials: O
authors.lastname: Hentic
authors.forename: Frédérique
authors.initials: F
authors.lastname: Maire
authors.forename: Philippe
authors.initials: P
authors.lastname: Levy
authors.forename: Philippe
authors.initials: P
authors.lastname: Ruszniewski