title: Multiple enlarged nerves on neurosonography: an unusual paraneoplastic case.
abstract: Multiple nerve enlargements at non-entrapment sites are usually caused by hereditary or acquired immune-mediated neuropathies.We describe a case of multifocal hypertrophic mononeuropathies detected by nerve sonography with a clinical picture of progressive mononeuritis multiplex caused by a paraneoplastic syndrome associated with anti-Hu antibodies. This case illustrates an unusual but important paraneoplastic differential diagnosis of progressive multifocal hypertrophic neuropathies. It emphasizes the role of nerve ultrasound in the diagnostic work-up of peripheral nervous system disorders.
authors.affiliation: Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. f.leypoldt@uke.de
authors.forename: Frank
authors.initials: F
authors.lastname: Leypoldt
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Friese
authors.forename: Josef
authors.initials: J
authors.lastname: Böhm
authors.forename: Tobias
authors.initials: T
authors.lastname: Bäumer
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D020364:Paraneoplastic Polyneuropathy / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D014463:Ultrasonography