title: Diffusion-weighted magnetic resonance for pulmonary nodules: 1.5 vs. 3 Tesla.
abstract: The usefulness of diffusion-weighted magnetic resonance for assessing malignant pulmonary nodules was examined in 58 patients with 76 (58 malignant, 18 benign) pulmonary nodules (1.0-5.6 cm) who underwent 1.5-T and 3-Tesla imaging and (18)F-fluorodeoxyglucose positron-emission tomography prior to surgery. The sensitivities and specificities of these techniques for discriminating benign and malignant nodules were compared. The apparent diffusion coefficients of the pulmonary nodules on 1.5-T and 3-T imaging correlated significantly. The sensitivities and specificities for discriminating benign and malignant lesions were similar among the 3 imaging techniques: 1.5-T imaging, 0.91 and 0.90; 3-T imaging, 0.88 and 0.94; positron-emission tomography, 0.94 and 0.94. The apparent diffusion coefficient on 1.5-T imaging showed a significant reverse correlation with positron-emission tomography, and the correlation between 3-T imaging and positron-emission tomography was marginally significant. Both 1.5-T and 3-T diffusion-weighted magnetic resonance imaging modalities are equally useful for assessing malignant pulmonary nodules.
authors.affiliation: Department of Thoracic Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Yasuomi
authors.initials: Y
authors.lastname: Ohba
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nomori
authors.forename: Takeshi
authors.initials: T
authors.lastname: Mori
authors.forename: Kenji
authors.initials: K
authors.lastname: Shiraishi
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Namimoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katahira
mesh_terms: D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007564:Japan; D008171:Lung Diseases / Q000175:diagnosis* / Q000601:surgery; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery; D055613:Multiple Pulmonary Nodules / Q000175:diagnosis* / Q000601:surgery; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011446:Prospective Studies; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18