title: [Antibiotic sensitivity of beta-hemolytic streptococci isolated from throat swabs and purulent material].
abstract: The aim of this study was to evaluate the prevalence and susceptibility of beta-hemolytic streptococci isolated from throat swabs (142--29.9%) and purulent material (333--70.1%) taken from patients treated at University Hospital dr. A. Jurasz in Bydgoszcz Collegium Medicum. L. Rydygier in Bydgoszcz, Nicolaus Copernicus University in Torun in 2005-2009. Of the 475 tested strains, 156 (32.8%) were identified as S. pyogenes. This species accounted for 38.8% of strains isolated from purulent material and 19.0% of swabs from the throat. Among the strains isolated from throat swabs of 62 (43.7%) were identified as Streptococcus group C. Only 5.1% strains were identified as Streptococcus group F. All strains of beta-hemolytic streptococci were susceptible to ampicillin or penicillin, fluoroquinolones, vancomycin and linezolid. Erythromycin-susceptible strains was 83.8%, and 89.1% for clindamycin. A total of 51.3% of erythromycin resistance strains had the cMLS(B) phenotype (63.3% for strains from throat swabs and 46.3% of the purulent materials). Sensitivity to tetracycline was characterized by 51.2% of strains of beta-hemolytic streptococci. The percentage of strains susceptible to this antibiotic among isolates from throat swabs was 63.1%, and purulent material--48.0%. The lowest percentage of strains susceptible to tetracycline (14.1%) were found among S. agalactiae and Streptococcus group G (33.6%) strains. During the study time, saw an increase in the percentage of strains susceptible to tetracycline and erythromycin.
authors.affiliation: Katedra i Zakład Mikrobiologii, Collegium Medicum im. A. Jurasza w Bydgoszczy UMK w Toruniu.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Jachna-Sawicka
authors.forename: Anna
authors.initials: A
authors.lastname: Pietrzak
authors.forename: Tomasz
authors.initials: T
authors.lastname: Bogiel
authors.forename: Eugenia
authors.initials: E
authors.lastname: Gospodarek
mesh_terms: D024881:Drug Resistance, Bacterial; D006460:Hemolysin Proteins / Q000378:metabolism; D006801:Humans; D008826:Microbial Sensitivity Tests; D010614:Pharynx / Q000382:microbiology*; D013045:Species Specificity; D013291:Streptococcus / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism; D013492:Suppuration / Q000382:microbiology*
chemical_list: D006460:Hemolysin Proteins