title: Clinical outcome after percutaneous endoscopic gastrostomy in children with malignancies.
abstract: Percutaneous endoscopic gastrostomies (PEG) are little-used in pediatric oncology. We evaluated complications and efficacy of PEGs in children with malignancies in a retrospective case series. Outcome measures were infection and weight gain. Sixteen PEGs were inserted in 14 patients (mean age 10.3 years; SD 5.6). Sixteen wound infections occurred in nine children (3.7 episodes/1,000 days). Mean weight-for-age z-score fell from diagnosis to PEG placement (-0.68 (SD 1.2) to -1.32 (SD 1.26); P < 0.001) but stabilized afterward. Two (12%) were removed early. PEG placement reversed early weight loss and infectious complications did not usually lead to early PEG removal.
authors.affiliation: Department of Gastroenterology and Clinical Nutrition, Victoria, Australia.
authors.forename: Deena M
authors.initials: DM
authors.lastname: Parbhoo
authors.forename: Karin
authors.initials: K
authors.lastname: Tiedemann
authors.forename: Anthony G
authors.initials: AG
authors.lastname: Catto-Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D016099:Endoscopy, Gastrointestinal; D004750:Enteral Nutrition; D005774:Gastrostomy; D006801:Humans; D007223:Infant; D044342:Malnutrition / Q000517:prevention & control; D009369:Neoplasms / Q000188:drug therapy*; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control; D016896:Treatment Outcome; D015430:Weight Gain; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents