title: BNCT for locally recurrent head and neck cancer: preliminary clinical experience from a phase I/II trial at Tsing Hua Open-Pool Reactor.
abstract: To introduce our preliminary experience of treating locally and regionally recurrent Head and Neck cancer patients at Tsing Hua Open-Pool Reactor in Taiwan, four patients (M/F=3/1, median age 68 Y/O) were enrolled. BNCT with BPA (400 mg/kg) injected in 2 phases and prescription dose of 12-35 Gy (Eq.)/fraction for 2 fractions at 30 day interval can be given with sustained blood boron concentration and tolerable early toxicities for recurrent H & N cancer.
authors.affiliation: Cancer Center, Taipei Veterans General Hospital, Taiwan, ROC. lwwang@vghtpe.gov.tw
authors.forename: L W
authors.initials: LW
authors.lastname: Wang
authors.forename: S J
authors.initials: SJ
authors.lastname: Wang
authors.forename: P Y
authors.initials: PY
authors.lastname: Chu
authors.forename: C Y
authors.initials: CY
authors.lastname: Ho
authors.forename: S H
authors.initials: SH
authors.lastname: Jiang
authors.forename: Y W H
authors.initials: YW
authors.lastname: Liu
authors.forename: Y H
authors.initials: YH
authors.lastname: Liu
authors.forename: H M
authors.initials: HM
authors.lastname: Liu
authors.forename: J J
authors.initials: JJ
authors.lastname: Peir
authors.forename: F I
authors.initials: FI
authors.lastname: Chou
authors.forename: S H
authors.initials: SH
authors.lastname: Yen
authors.forename: Y L
authors.initials: YL
authors.lastname: Lee
authors.forename: C W
authors.initials: CW
authors.lastname: Chang
authors.forename: C S
authors.initials: CS
authors.lastname: Liu
authors.forename: Y W
authors.initials: YW
authors.lastname: Chen
authors.forename: K
authors.initials: K
authors.lastname: Ono
mesh_terms: D000368:Aged; D016754:Boron Neutron Capture Therapy / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009364:Neoplasm Recurrence, Local; D049268:Positron-Emission Tomography; D013624:Taiwan; D014057:Tomography, X-Ray Computed