title: Isolated uveal tuberculoma masquerading as an intraocular tumor in an immunocompetent patient-a clinical-pathologic study with diagnosis by PCR.
abstract: OBJECTIVE
  The aim of this article is to report a case of uveal tuberculoma simulating an intraocular tumor in which the diagnosis was only possible by polymerase chain reaction (PCR) analysis.
  
  
  METHODS
  This is a case report.
  
  
  RESULTS
  A36-year-old male presented with a progressive growing intraocular tumor and no history or positive test for other systemic disease. The eye eventually turned blind and painful and was enucleated. Histopathologic analysis revealed a granulomatous reaction and caseation necrosis but failed to identify any causative microorganisms. Final tuberculosis diagnosis was only possible by quantitative PCR.
  
  
  CONCLUSIONS
  Isolated uveal tuberculoma can present in an otherwise healthy patient with negative systemic tuberculosis evaluation. PCR can be used to confirm tuberculosis when other methods have failed.
authors.affiliation: Federal University of Bahia, Salvador, Bahia, Brazil, eduardomarback@uol.com.br.
authors.forename: Eduardo F
authors.initials: EF
authors.lastname: Marback
authors.forename: Epaminondas
authors.initials: E
authors.lastname: de Souza Mendes
authors.forename: Ricardo D
authors.initials: RD
authors.lastname: Chagas Oliveira
authors.forename: Jignesh G
authors.initials: JG
authors.lastname: Parikh
authors.forename: Narsing A
authors.initials: NA
authors.lastname: Rao