title: A mirror-image tetramolecular DNA quadruplex.
abstract: L-DNA, the mirror image of natural DNA forms structures of opposite chirality. We demonstrate here that a short guanine rich L-DNA strand forms a tetramolecular quadruplex with the same properties as a D-DNA strand of identical sequence, besides an inverted circular dichroism spectra. L- and D-strands self exclude when mixed together, showing that the controlled parallel self-assembly of different G-rich strands can be obtained through L-DNA use.
authors.affiliation: Université de Bordeaux, Laboratoire ARNA, F-33000 Bordeaux, France.
authors.forename: Phong Lan Thao
authors.initials: PL
authors.lastname: Tran
authors.forename: Rui
authors.initials: R
authors.lastname: Moriyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Maruyama
authors.forename: Bernard
authors.initials: B
authors.lastname: Rayner
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Mergny
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000235:genetics; D054856:G-Quadruplexes; D020862:GC Rich Sequence; D007700:Kinetics; D013237:Stereoisomerism; D044366:Transition Temperature
chemical_list: D004247:DNA