title: Use of natural antimicrobials from a food safety perspective for control of Staphylococcus aureus.
abstract: Staphylococcus aureus (S. aureus) is an important foodborne and environmental pathogen that can produce toxins in foods and cause infections in soft tissues. S. aureus that have developed resistance to the conventional antimicrobials are commonly called Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant S. aureus (VRSA). Their prevalence is believed to be due to the widespread use of antibiotics. Therefore, natural antimicrobials are in urgent demand as alternatives to conventional antibiotics to treat S. aureus infections. In this review, natural antimicrobials from plant, animal and microbiological origins are discussed, including their mode of action and mechanisms of bacterial resistance, major components, chemical structure, effectiveness, synergistic effects and future prospects.
authors.affiliation: Institute of Quality Standard & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 10081, China.
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.forename: Arunachalam
authors.initials: A
authors.lastname: Muthaiyan
authors.forename: Corliss A
authors.initials: CA
authors.lastname: O'Bryan
authors.forename: John E
authors.initials: JE
authors.lastname: Gustafson
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: Philip G
authors.initials: PG
authors.lastname: Crandall
authors.forename: Steven C
authors.initials: SC
authors.lastname: Ricke
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005419:Flavonoids / Q000494:pharmacology; D005516:Food Microbiology; D059022:Food Safety; D007502:Iron Chelating Agents / Q000494:pharmacology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D009822:Oils, Volatile / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects*; D020713:Vancomycin Resistance
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids; D007502:Iron Chelating Agents; D009822:Oils, Volatile