title: Toxoplasma gondii: usefulness of ROP1 recombinant antigen in an immunoglobulin G avidity assay for diagnosis of acute toxoplasmosis in humans.
abstract: The results present in this study suggest that the Toxoplasma gondii recombinant ROP1 antigen in an IgG avidity test can be useful for detection of acute stage of infection. Specific antibodies of low avidity were detected in most of the sera from individuals with acute toxoplasmosis, while the absence or specific antibodies of high avidity were detected in sera from patients with chronic infection.
authors.affiliation: Gdańsk University of Technology, Chemical Faculty, Department of Microbiology, Gdańsk, Poland.
authors.forename: Lucyna
authors.initials: L
authors.lastname: Holec-Gasior
authors.forename: Dorota
authors.initials: D
authors.lastname: Drapała
authors.forename: Dariusz
authors.initials: D
authors.lastname: Lautenbach
authors.forename: Józef
authors.initials: J
authors.lastname: Kuri
mesh_terms: D000913:Antibodies, Protozoan / Q000097:blood*; D000915:Antibody Affinity / Q000276:immunology*; D000953:Antigens, Protozoan / Q000097:blood / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D007075:Immunoglobulin M / Q000276:immunology; D008565:Membrane Proteins / Q000097:blood / Q000276:immunology*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology; D011994:Recombinant Proteins / Q000097:blood / Q000276:immunology; D012680:Sensitivity and Specificity; D014122:Toxoplasma / Q000276:immunology* / Q000472:pathogenicity; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000276:immunology / Q000469:parasitology
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008565:Membrane Proteins; C117001:ROP 1 protein, Toxoplasma gondii; D011994:Recombinant Proteins