title: [The research practice of anti-arrhythmic agents targeting on potassium ion channel].
abstract: Due to the complicated pathogenesis of cardiac arrhythmia, the safe and effective therapeutic strategies for cardiac arrhythmia remain an urgent medical problems in the recent years. In this paper, we introduced the research practice of anti-arrhythmic agents targeting on potassium ion channel. The research progress of anti-arrhythmic agents in up-to-date literatures were also reviewed and prospected.
authors.affiliation: Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Yang
authors.forename: Xiao-Jian
authors.initials: XJ
authors.lastname: Wang
authors.forename: Yi-Qun
authors.initials: YQ
authors.lastname: Tang
authors.forename: Qi-Dong
authors.initials: QD
authors.lastname: You
mesh_terms: D000638:Amiodarone / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D000077764:Dronedarone; D006801:Humans; D006827:Hydantoins; D048289:Imidazolidines / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D015394:Molecular Structure; D010879:Piperazines / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D026902:Potassium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use; D015221:Potassium Channels / Q000187:drug effects*
chemical_list: D000889:Anti-Arrhythmia Agents; D006827:Hydantoins; D048289:Imidazolidines; D010879:Piperazines; D026902:Potassium Channel Blockers; D015221:Potassium Channels; C086123:azimilide; D000077764:Dronedarone; D000638:Amiodarone