title: Treatment of plastic bronchitis by orthotopic heart transplantation.
abstract: This case illustrates the successful use of orthotopic heart transplantation for the treatment of plastic bronchitis in a 6-year-old boy with hypoplastic left heart syndrome, which developed 2 years after Fontan procedure. Transplantation was undertaken after he failed medical management of airway obstruction. He is currently 1-year post-cardiac transplantation and has no evidence of plastic bronchitis despite weaning of an aggressive airway clearance regimen.
authors.affiliation: The Johns Hopkins Hospital, 600N Wolfe Street, Baltimore, MD 21287, USA. jlaubis1@jhmi.edu
authors.forename: Jamie E
authors.initials: JE
authors.lastname: Laubisch
authors.forename: Diana M
authors.initials: DM
authors.lastname: Green
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Mogayzel
authors.forename: W
authors.initials: W
authors.lastname: Reid Thompson
mesh_terms: D000402:Airway Obstruction / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D001991:Bronchitis / Q000473:pathology* / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D002648:Child; D005337:Fibrin / Q000378:metabolism; D016027:Heart Transplantation; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000601:surgery*; D008297:Male
chemical_list: D005337:Fibrin