title: Neurogenic stunned myocardium presenting as left ventricular hypertrabeculation in childhood: a variant of Takotsubo cardiomyopathy?
abstract: OBJECTIVE
  To report the first case of neurogenic stunned myocardium presenting with heart left ventricle noncompaction requiring intensive care in the perioperative period of tension tumor-induced hydrocephalus.
  
  
  METHODS
  Case report and literature review. Our Institutional Review Board waived the need for consent.
  
  
  METHODS
  A 12-yr-old female with intracranial astrocytoma and hypertensive hydrocephalus presented with severe heart dysfunction and life-threatening ventricular ectopies intraoperatively. A severe heart failure developed requiring hemodynamic and ventilatory support for 10 days. Echocardiography showed a transient noncompaction aspect of the left ventricular wall, further confirmed by a cardiac magnetic resonance image. The noncompaction aspect lasted until 15 days postadmission, as was the case for the QT interval prolongation; no life-threatening ectopies were demonstrated on the subsequent Holter electrocardiogram monitoring.
  
  
  CONCLUSIONS
  This report describes a unique presentation of myocardial stunning in association with an intracranial illness, namely, a hypertensive hydrocephalus complicating an intracranial neoplasm.
authors.affiliation: Department of Pediatrics, Catholic University Medical School, A.Gemelli Hospital, Rome, Italy.
authors.forename: Gabriella
authors.initials: G
authors.lastname: De Rosa
authors.forename: Manuela
authors.initials: M
authors.lastname: Pardeo
authors.forename: Concezio
authors.initials: C
authors.lastname: Di Rocco
authors.forename: Domenico
authors.initials: D
authors.lastname: Pietrini
authors.forename: Sonia
authors.initials: S
authors.lastname: Mensi
authors.forename: Eleonora
authors.initials: E
authors.lastname: Stival
authors.forename: Alessia
authors.initials: A
authors.lastname: De Nisco
authors.forename: Laura
authors.initials: L
authors.lastname: Marzano
authors.forename: Daniele
authors.initials: D
authors.lastname: De Luca
authors.forename: Marco
authors.initials: M
authors.lastname: Piastra
mesh_terms: D001254:Astrocytoma / Q000150:complications; D001932:Brain Neoplasms / Q000150:complications; D002648:Child; D003937:Diagnosis, Differential; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000503:physiopathology; D017682:Myocardial Stunning / Q000175:diagnosis* / Q000503:physiopathology*; D009493:Neurosurgery / Q000379:methods; D054549:Takotsubo Cardiomyopathy