title: Domino reactions for the synthesis of bridged bicyclic frameworks: fast access to bicyclo[n.3.1]alkanes.
abstract: In the current bid for synthetic efficiency, multiple bond-forming transformations are becoming a key concept in organic synthesis. In this context, domino protocols have become increasingly common in the synthesis of bicyclic systems. This tutorial review aims at providing a short but authoritative overview of this topic, focusing on the preparation of bridged bicyclo[n.3.1]alkane systems, and is organized according to the number of rings created in the key domino process.
authors.affiliation: Departamento de Química Orgánica y Farmacéutica. Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain.
authors.forename: Miriam
authors.initials: M
authors.lastname: Ruiz
authors.forename: Pilar
authors.initials: P
authors.lastname: López-Alvarado
authors.forename: Giorgio
authors.initials: G
authors.lastname: Giorgi
authors.forename: J Carlos
authors.initials: JC
authors.lastname: Menéndez
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry*; D007700:Kinetics; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D000473:Alkanes; D019086:Bridged Bicyclo Compounds, Heterocyclic; D009942:Organometallic Compounds