title: Case files of the medical toxicology fellowship at Banner Good Samaritan Medical Center in Phoenix, AZ: methemoglobinemia following dapsone exposure.
abstract: Acquired methemoglobinemia is a common, potentially fatal syndrome that can occur as a result of exposure to numerous xenobiotics. A case report of a 14-month-old female who developed methemoglobinemia following a dapsone ingestion. The child was treated with numerous boluses of methylene blue and ultimately required a continuous infusion of methylene blue. The common causes of methemoglobinemia, as well as the underlying pathophysiology, diagnosis, and treatment strategies are discussed.
authors.affiliation: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Canning
authors.forename: Michael
authors.initials: M
authors.lastname: Levine
mesh_terms: D000890:Anti-Infective Agents / Q000506:poisoning*; D001130:Arizona; D003490:Cyanosis / Q000097:blood / Q000188:drug therapy / Q000473:pathology; D003622:Dapsone / Q000506:poisoning*; D005260:Female; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000188:drug therapy; D008751:Methylene Blue / Q000008:administration & dosage; D011041:Poisoning / Q000097:blood / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000890:Anti-Infective Agents; D003622:Dapsone; D008751:Methylene Blue