title: [Necessity to define thyroid reference values for better clinical interpretation].
abstract: Discordances were observed with thyroid reference range from BCF Access 2 analyser. The purpose of this study was to establish specific reference range value for free thyroxine (FT4), free triiodothyronine (FT3) and thyrotropin (TSH) in adult Meaux Hospital population. Samples from 308 adults aged from 18 to 65 years were studied. Patients (no pregnancy and no iodine contrast media used) after informed consent, were exempted of thyroidal, cardiac, renal, multiple-organ-failure illnesses. Thyroid assays, anti-TPO and anti-TG levels were measured on the BCF Access2 immunoassay system. This work exposes difficulties to define range values in order to better use the biomarker in the clinical context.
authors.affiliation: Laboratoire de biochimie, Centre hospitalier, Meaux. e-plouvier@ch-meaux.fr
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Plouvier
authors.forename: Laurent
authors.initials: L
authors.lastname: Alliot
authors.forename: Basile
authors.initials: B
authors.lastname: Bigorie
authors.forename: Caroline
authors.initials: C
authors.lastname: Kowalski
authors.forename: Virginie
authors.initials: V
authors.lastname: Medeau
authors.forename: François
authors.initials: F
authors.lastname: Thuillier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*; D055815:Young Adult
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine