title: Rest interval between resistance exercise sets: length affects volume but not creatine kinase activity or muscle soreness.
abstract: OBJECTIVE
  To compare differences between two different rest interval lengths between sets on the volume completed, muscle damage and muscle soreness during a resistance exercise bout.
  
  
  METHODS
  Twenty-eight healthy sedentary men (18 ± 1 y old) volunteered to participate in this study and were divided into the 1 min (1RI; n = 14) or 3 min (3RI; n = 14) rest interval length between sets. They were submitted to maximal voluntary isometric contraction strength (MVC) and then performed a resistance exercise protocol constituted for three sets of biceps curl at 40% of MVC with 1 min (1RI group) or 3 min (3RI group) interval length between sets. Each bout was performed to voluntary fatigue and the workout volume completed was calculated. Subjects provided blood samples before each bout, and at 24, and 48 h following exercise to evaluate serum CK activity. Muscle soreness was analyzed through visual analog scale, which was presented to subjects before first bout, immediately after exercise protocol and at 24, and 48 h following exercise.
  
  
  RESULTS
  The results demonstrated that the subjects with longer rest intervals provide greater workout volume as expected, but there were no differences in serum CK activity and muscle soreness between groups.
  
  
  CONCLUSIONS
  Training with high-volume, low-intensity resistance training, exercising with short rest intervals does not appear to present any additional challenge to recovery in untrained subjects.
authors.affiliation: Laboratory of Physiology and Biokinetics, Itaperuna, RJ, Brazil.
authors.forename: Renato
authors.initials: R
authors.lastname: Evangelista
authors.forename: Rafael
authors.initials: R
authors.lastname: Pereira
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Hackney
authors.forename: Marco
authors.initials: M
authors.lastname: Machado
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D052283:Creatine Kinase, MM Form / Q000097:blood*; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D018763:Muscle Fatigue; D018482:Muscle, Skeletal / Q000201:enzymology / Q000473:pathology / Q000503:physiopathology*; D009929:Organ Size; D010146:Pain / Q000209:etiology*; D010147:Pain Measurement; D020127:Recovery of Function; D055070:Resistance Training / Q000009:adverse effects / Q000379:methods*; D057185:Sedentary Behavior; D013997:Time Factors; D055815:Young Adult
chemical_list: D015415:Biomarkers; D052283:Creatine Kinase, MM Form