title: [Molecular mechanisms of proliferation and differentiation of spermatogonial stem cells].
abstract: Clinically many patients with non-obstructive azoospermia cannot benefit from assisted reproductive technology for absence of spermatozoa. However, the achievement in the studies of spermatogonial stem cells has brought hope to this cohort. This article reviews the molecular mechanisms of the proliferation and differentiation of spermatogonial stem cells, in such aspects as related genes, growth factors, and so on.
authors.affiliation: Research Institute of Andrology, Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210046,China. daling11@126.com
authors.forename: Da-lin
authors.initials: DL
authors.lastname: Sun
authors.forename: Xin-dong
authors.initials: XD
authors.lastname: Zhang
authors.forename: Bao-fang
authors.initials: BF
authors.lastname: Jin
mesh_terms: D053713:Azoospermia / Q000628:therapy; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D008297:Male; D013093:Spermatogonia / Q000166:cytology*; D013234:Stem Cells / Q000166:cytology*