title: [Cardiopulmonary exercise test in adults with congenital heart disease].
abstract: Cardiopulmonary exercise testing (CPET) gives important information about functional capacity by direct measurement of exercise respiratory gas exchange. It provides assessment of the integrative exercise responses involving the cardiovascular, respiratory and muscle-skeletal systems which are not adequately investigated through the measurement of individual organ system function. CPET involves measurements of oxygen uptake (VO2), carbon dioxide production (VCO2) and several ventilatory measures. CPET is increasingly being used as a clinical tool to determine functional capacity, prognosis and potential need for medical or surgical interventions in patients affected by congenital heart disease (CHD). Also in this population, peak VO2 and slope VE/VCO2 are the most predictive parameters in terms of mortality and need of hospitalization. Cyanotic patients with Esisenmenger syndrome show the worst functional limitation and consequently the worst prognosis. This article provides basic and practical information about CPET and focuses on its interpretation in patients with CHD.
authors.affiliation: Centro di Cardiologia-Cardiochirurgia Pediatrica e Cardiopatie Congenite dell'Adulto, I.R.C.C.S.-Policlinico San Donato, San Donato Milanese, Milano, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Negura
authors.forename: A
authors.initials: A
authors.lastname: Micheletti
authors.forename: M
authors.initials: M
authors.lastname: Chessa
authors.forename: R
authors.initials: R
authors.lastname: Calaciura
authors.forename: A
authors.initials: A
authors.lastname: Saracino
authors.forename: G
authors.initials: G
authors.lastname: Butera
authors.forename: L
authors.initials: L
authors.lastname: Piazza
authors.forename: C
authors.initials: C
authors.lastname: Arcidiacono
authors.forename: M
authors.initials: M
authors.lastname: Carminati
mesh_terms: D000328:Adult; D005080:Exercise Test; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006331:Heart Diseases / Q000151:congenital* / Q000175:diagnosis*; D006801:Humans