title: [Concentration assessment of interleukin 8 in serum at children with uveitis].
abstract: OBJECTIVE
  Uveitis in children is a visual threatening disease with a complication rate of more than 75%. At the children the uveitis differs in several aspect from adults like: clinical presentation or complication of disease. The etiology of uveitis is still unknown, but T lymphocytes are generally key mediators of the pathogenesis of uveitis. In our study we evaluate IL-8 concentration in serum in uveitis patients.
  
  
  METHODS
  Serum sample were collected from 28 uveitis patients and 20 people from control group. The level IL-8 was measured with specific enzyme- linked immunoassays ELISA methods (R & D Systems).
  
  
  RESULTS
  Level of IL-8 in uveitis group was a significant higher (p<0.04) compared with control group.
  
  
  CONCLUSIONS
  Increased levels of interleukin 8 in serum of children with uveitis may suggest innate immune mechanisms in the acute disease.
authors.affiliation: Z Zakładu Laboratoryjnej Diagnostyki Pediatrycznej Uniwersytetu Medycznego w Białymstoku. zelazowskab@wp.pl
authors.forename: Beata
authors.initials: B
authors.lastname: Zelazowska-Rutkowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mrugacz
authors.forename: Jolanta
authors.initials: J
authors.lastname: Wysocka
authors.forename: Alina
authors.initials: A
authors.lastname: Bakunowicz-Łazarczyk
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D002669:Child Welfare; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D016209:Interleukin-8 / Q000097:blood*; D008297:Male; D014605:Uveitis / Q000097:blood* / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D016209:Interleukin-8