title: Surgical outcome in patients with concomitant-infected abdominal aortic aneurysm and spondylitis.
abstract: The coexistence of infected abdominal aortic aneurysms and spondylitis is rare but challenging. The etiology of the infection is frequently unknown. The aim of this study was to review the outcome of surgical repair of this complex disease. From 2004 to 2006, six patients were identified who underwent surgical repair of concomitant infected abdominal aortic aneurysm and spondylitis. Diagnosis, treatment and intermediate-term results are presented. The clinical manifestation included the signs of ongoing systemic infection, neurological deficit and abdominal or back pain. Computed tomography revealed abdominal aortic aneurysms associated with polysegmental spondylitis. Patients underwent radical debridement and aortic replacement with cryopreserved aortic allografts or silver-coated prostheses followed by antibiotic treatment. Only one patient received a simultaneous anterior vertebral stabilization. Greater omentum was placed in the abscess cavity. Intensive care unit and hospital stay averaged 3.0 and 28.0 days, respectively. Organisms were identified in all but one patient. Over a follow-up period of 4.4 years, four patients are alive and showing freedom from infection, and two patients had died unrelated at seven and eight months. In conclusion, surgical repair of infected aortic aneurysms with resection of infected tissues and implantation of a homograft or a silver-coated prosthesis achieved favorable results in this sick patient group. Simultaneous vertebral stabilization is rarely necessary.
authors.affiliation: Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Zhang
authors.forename: Omke E
authors.initials: OE
authors.lastname: Teebken
authors.forename: Theodosios
authors.initials: T
authors.lastname: Bisdas
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.forename: Maximilian
authors.initials: M
authors.lastname: Pichlmaier
mesh_terms: D000368:Aged; D000785:Aneurysm, Infected / Q000453:epidemiology* / Q000382:microbiology / Q000601:surgery*; D001011:Aorta / Q000637:transplantation*; D017544:Aortic Aneurysm, Abdominal / Q000453:epidemiology* / Q000601:surgery*; D001019:Aortic Rupture; D019917:Blood Vessel Prosthesis Implantation; D015897:Comorbidity; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013166:Spondylitis / Q000453:epidemiology* / Q000601:surgery*; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D058017:Vascular Grafting