title: Cerebellar degeneration as presenting symptom of recurrent endometrial stromal sarcoma with sex-cord elements.
abstract: We report a 66-year-old woman with slowly progressive ataxia due to cerebellar atrophy. Imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space. A biopsy identified the lesions as metastases of a low-grade endometrial stromal sarcoma containing sex-cord elements. The histological appearance was identical to a uterine tumor the patient was treated for with hysterectomy 16 years before. The metastases were removed surgically, and after 3 months ataxia had regressed. We conclude that the presenting cerebellar degeneration in this patient resulted from the metastatic recurrence of the endometrial tumor.
authors.affiliation: Departments of Neurology, Heinrich Heine University, Duesseldorf, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Gliem
authors.forename: Dimitris
authors.initials: D
authors.lastname: Panayotopoulos
authors.forename: Peter
authors.initials: P
authors.lastname: Feindt
authors.forename: Sebastian
authors.initials: S
authors.lastname: Heikaus
authors.forename: Markus C
authors.initials: MC
authors.lastname: Fleisch
authors.forename: Rüdiger J
authors.initials: RJ
authors.lastname: Seitz