title: Merkel cell carcinoma.
abstract: Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis and are thought to function as touch receptors. Here, we describe a case of MCC in a 71-year-old female and provide an up-to-date review of the literature pertinent to the management of MCC.
authors.affiliation: Northern General Hospital, Sheffield, United Kingdom.
authors.forename: S
authors.initials: S
authors.lastname: Wallis
authors.forename: A
authors.initials: A
authors.lastname: Durham-Hall
authors.forename: N
authors.initials: N
authors.lastname: Tandon
authors.forename: T M
authors.initials: TM
authors.lastname: Brotherston
authors.forename: B M
authors.initials: BM
authors.lastname: Shrestha
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D015266:Carcinoma, Merkel Cell / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*
chemical_list: D000970:Antineoplastic Agents