title: Rhodium-catalyzed decarboxylative cycloaddition route to substituted anilines.
abstract: A convenient method for preparing substituted anilines via a Rh-catalyzed [2 + 2 + 2] cycloaddition reaction of diynes and 2-oxazolone was discovered. The initial cycloaddition adducts undergo facile decarboxylation of carbon dioxide to afford aniline products. Reaction conditions are mild, and only 3 mol % Rh catalyst is required. High regioselectivity was observed when an unsymmetrical diyne was used as a starting material.
authors.affiliation: Department of Chemistry, University of Utah, Salt Lake City, Utah 84112-0850, United States.
authors.forename: Kainan
authors.initials: K
authors.lastname: Zhang
authors.forename: Janis
authors.initials: J
authors.lastname: Louie
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D010081:Oxazolone / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D010081:Oxazolone; D012238:Rhodium; C023650:aniline