title: Lung carcinoma with hypertrophic osteoarthropathy in a teenager.
abstract: Hypertrophic osteoarthropathy (HOA) characterised by arthralgia, clubbing and periosteal proliferation of long bones, is rarely encountered in children and adolescents. Whereas in adults over 80% of cases are associated with malignancy, in children the majority of cases are due to non-neoplastic causes such as cystic fibrosis, bilary atresia and congenital heart disease. Up to 5% of adults with lung cancer demonstrate signs of HOA. However, lung cancer is extremely uncommon in children and young people. Here we report a case of lung adenocarcinoma in an 18 year old male associated with HOA present both at diagnosis and at subsequent disease progression.
authors.affiliation: Department of Medical Oncology;
authors.forename: Rowan E
authors.initials: RE
authors.lastname: Miller
authors.forename: Rowland O
authors.initials: RO
authors.lastname: Illing
authors.forename: Jeremy S
authors.initials: JS
authors.lastname: Whelan