title: Chiral separation of D,L-mandelic acid through cellulose membranes.
abstract: This work reports the chiral separation of D,L-mandelic acid with cellulose membranes. Cellulose was chosen as membrane material because it possesses multichiral carbon atoms in its molecular structure unit. The flux and permselective properties of membrane using aqueous solutions of D,L-mandelic acid as feed solution was studied. The top surface and cross-section morphology of the resulting membrane were examined by scanning electron microscopy. When the membrane was prepared with 8.1 wt % cellulose and 8.1 wt % LiCl in the DMA casting solution, and the operating pressure and feed concentration of racemate were 0.0125 MPa and 0.5 mg/ml, respectively, over 90% of enantiomeric excess could be obtained. This is the first report that the cellulose membrane is used for isolating the optical isomers of D,L-mandelic acid. Chirality, 2011.
authors.affiliation: Department of Chemistry, Yunnan Normal University, Kunming, People's Republic of China.
authors.forename: Chao
authors.initials: C
authors.lastname: Ma
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Ai
authors.forename: Sheng-Ming
authors.initials: SM
authors.lastname: Xie
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Lv
authors.forename: Hai-Qin
authors.initials: HQ
authors.lastname: Shan
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Yuan
mesh_terms: D002482:Cellulose / Q000032:analysis / Q000737:chemistry*; D008333:Mandelic Acids / Q000737:chemistry*; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D011312:Pressure; D013237:Stereoisomerism
chemical_list: D008333:Mandelic Acids; D008567:Membranes, Artificial; D002482:Cellulose; C037938:mandelic acid