title: Antimicrobial activity of undecan-x-ones (x = 2-4).
abstract: As a continuation of our research on the biological activity of undecan-x-ones (x = 2-4), their antimicrobial activity towards bacteria Escherichia coli and Bacillus subtilis, yeast Candida mycoderma and mould Aspergillus niger, was investigated. The population viability of the tested microbial strains in the presence of undecan-x-ones was determined by the impedimetric and agar disc diffusion methods. Undecan-x-ones showed low antibacterial activity towards both Gram-positive and Gram-negative bacteria. Undecan-2-one and undecan-3-one exhibited high activity towards C. mycoderma. All undecan-x-ones expressed the strongest effect on A. niger. The tests have proven that due to high fungistatic activity undecan-x-ones can be used to aid stabilization of food and cosmetic matrices.
authors.affiliation: Institute of Fermentation Technology and Microbiology, Technical University of Łódź, Poland. akunicka@p.lodz.pl
authors.forename: Alina
authors.initials: A
authors.lastname: Kunicka-Styczyńska
authors.forename: Julia
authors.initials: J
authors.lastname: Gibka
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects* / Q000254:growth & development; D001412:Bacillus subtilis / Q000187:drug effects* / Q000254:growth & development; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D007659:Ketones / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D000890:Anti-Infective Agents; D007659:Ketones; C526928:undecan-2-one