title: Histology of damaged acetabular cartilage in symptomatic femoroacetabular impingement: an observational analysis.
abstract: This prospective study on symptomatic adult patients with femoroacetabular impingement (FAI) who underwent open surgical intervention for management was designed to identify any obvious histological differences in the damaged acetabular cartilage within different subgroups of FAI. 20 patients underwent surgical intervention following safe surgical dislocation of the hip. There were 6 cases of cam impingement, 5 cases of pincer impingement and 9 of the mixed type. Pincer impingement cases demonstrated a characteristic focal, well-circumscribed and localized area of severe damage. On the other hand, cases with cam impingement showed a diffuse area of involvement affecting a larger surface of the acetabular cartilage, with degenerative changes, superficial erosions and some discontinuities. A small biopsy specimen of the acetabular rim including bone, cartilage and labrum from the affected zone was obtained in all cases. Histological evaluation was performed under normal and polarized light microscopy. Histological findings helped corroborate the pre-operative diagnosis and also define the unique nature of impingement and specific damage according to the type of impingement.
authors.affiliation: Department of Orthopedic Surgery, Inselspital, Bern - Switzerland.
authors.forename: Sandro
authors.initials: S
authors.lastname: Kohl
authors.forename: Harish S
authors.initials: HS
authors.lastname: Hosalkar
authors.forename: P
authors.initials: P
authors.lastname: Mainil-Varlet
authors.forename: Andreas
authors.initials: A
authors.lastname: Krueger
authors.forename: Lorenz
authors.initials: L
authors.lastname: Buechler
authors.forename: Klaus
authors.initials: K
authors.lastname: Siebenrock
mesh_terms: D000077:Acetabulum / Q000473:pathology* / Q000601:surgery; D000328:Adult; D001182:Arthroscopy; D001706:Biopsy; D002358:Cartilage, Articular / Q000473:pathology*; D005260:Female; D057925:Femoracetabular Impingement / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods; D011446:Prospective Studies; D012720:Severity of Illness Index