title: Monitoring the copper content of serum and urine in pregnancies complicated by preeclampsia.
abstract: Preeclampsia is an important cause of maternal and perinatal mortality worldwide. The etiology of this relatively common medical complication of pregnancy, however, remains unknown. The aim of this study was to compare the copper concentrations in serum and urine samples of preeclamptic and normotensive pregnant women to establish the possible contribution of this parameter to the etiology of this condition. Ninety-five preeclamptic and 92 normotensive pregnant women were enrolled in a cross-sectional study. The Cu content of serum and 24-h urine was compared among the women. The individual samples were analyzed for copper by atomic absorption spectrometry. The obtained data were recorded and analyzed statistically using t test, X2. Comparing the Cu concentrations in serum and urine samples of preeclamptic and normotensive pregnant women, significant differences between the two groups were observed. Obtained results of this study revealed that Cu content of serum and urine is increased in preeclamptic pregnancy.
authors.affiliation: Faculty of Nursing and Midwifery, Qazvin University of Medical Sciences, P.O. Box 34197-59811, Qazvin, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Ranjkesh
authors.forename: Hadigheh Kazemi
authors.initials: HK
authors.lastname: Jaliseh
authors.forename: Shokohosadat
authors.initials: S
authors.lastname: Abutorabi
mesh_terms: D000328:Adult; D001034:Apgar Score; D001724:Birth Weight; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002570:Ceruloplasmin / Q000378:metabolism; D003300:Copper / Q000032:analysis* / Q000097:blood / Q000652:urine; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000652:urine; D007231:Infant, Newborn; D008991:Monitoring, Physiologic; D011225:Pre-Eclampsia / Q000097:blood* / Q000652:urine*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011507:Proteinuria / Q000652:urine; D012959:Socioeconomic Factors; D013054:Spectrophotometry, Atomic; D055815:Young Adult
chemical_list: D003300:Copper; D002570:Ceruloplasmin