title: Changes in homocysteine and 8-iso-PGF(2a) levels in football and hockey players after a match.
abstract: The aim of the present study was to evaluate the levels of homocysteine and 8-iso PGF(2a) in football and hockey players before and soon after a match, on the predisposition for development of atherosclerosis. We measured 8-iso-PGF(2a) and homocysteine in 21 football athletes aged 21.8 ± 3.7 years old and 18 hockey athletes 22.2 ± 3.3 years old, respectively. All the athletes presented significant increases in serum homocysteine levels following the match (p = 0.001 for football and p = 0.001 for hockey players) Also a statistically significant increase of 8-iso-PGF(2a) levels was found in hockey and football athletes following the match (p < 0.001 and p = 0.071). Our findings suggest that strenuous exercise such as a football or a hockey match causes a marked increase in serum homocysteine and 8-iso-PGF(2a). Due to the fact that homocysteine and 8-iso-PGF(2a) are contributing to atheromatosis, it may be useful to follow a restoration exercise program that involves mild exercise and to pay special attention to folate, vitamin B6, and vitamin B12 balance during the first 24 h after the match.
authors.affiliation: Department of Biological Chemistry, Medical School, University of Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Papapanagiotou
authors.forename: I
authors.initials: I
authors.lastname: Gissis
authors.forename: C
authors.initials: C
authors.lastname: Papadopoulos
authors.forename: A
authors.initials: A
authors.lastname: Souglis
authors.forename: G C
authors.initials: GC
authors.lastname: Bogdanis
authors.forename: I
authors.initials: I
authors.lastname: Giosos
authors.forename: A
authors.initials: A
authors.lastname: Sotiropoulos
mesh_terms: D000293:Adolescent; D000328:Adult; D050197:Atherosclerosis / Q000097:blood* / Q000453:epidemiology; D056352:Athletes; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000097:blood; D006688:Hockey / Q000502:physiology*; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D012916:Soccer / Q000502:physiology*; D055815:Young Adult
chemical_list: D006710:Homocysteine; C075750:8-epi-prostaglandin F2alpha; D015237:Dinoprost