title: Is small-bowel bacterial overgrowth an underdiagnosed disorder in children with gastrointestinal symptoms?
abstract: Small-bowel bacterial overgrowth (SBBO) has been implicated in chronic abdominal pain and irritable bowel syndrome in children. This was a retrospective study that aimed to assess the occurrence of SBBO by the lactulose breath hydrogen test in children referred primarily for investigation of carbohydrate malabsorption (n = 287). There were profiles indicative of SBBO in 16% (39/250) of hydrogen-producing children. This indicated that SBBO may be more common in children with gastrointestinal symptoms and apparent carbohydrate malabsorption than previously recognised.
authors.affiliation: PERI Centre and Mechanisms in Cell Biology and Disease Research Group, Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.
authors.forename: Hilary F
authors.initials: HF
authors.lastname: Jones
authors.forename: Geoffrey P
authors.initials: GP
authors.lastname: Davidson
authors.forename: Doug A
authors.initials: DA
authors.lastname: Brooks
authors.forename: Ross N
authors.initials: RN
authors.lastname: Butler
mesh_terms: D015746:Abdominal Pain / Q000382:microbiology; D000293:Adolescent; D001765:Blind Loop Syndrome / Q000150:complications / Q000175:diagnosis*; D001944:Breath Tests; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003951:Diagnostic Errors; D006801:Humans; D006859:Hydrogen / Q000378:metabolism; D007223:Infant; D007421:Intestine, Small / Q000382:microbiology*; D043183:Irritable Bowel Syndrome / Q000382:microbiology*; D007792:Lactulose / Q000378:metabolism*; D008286:Malabsorption Syndromes / Q000382:microbiology*; D012189:Retrospective Studies
chemical_list: D007792:Lactulose; D006859:Hydrogen