title: Pituitary hyperplasia secondary to acquired hypothyroidism: case report.
abstract: OBJECTIVE
  despite recent progress in imaging, it is still difficult to distinguish between pituitary adenoma and hyperplasia, even using Magnetic Resonance Imaging (MRI) with gadolinium injection. We describe an example of reactive pituitary hyperplasia from primary hypothyroidism that mimicked a pituitary macroadenoma in a child.
  
  
  METHODS
  a 10 year old boy presented with headache and statural growth arrest. MRI revealed an intrasellar and suprasellar pituitary mass. Endocrine evaluation revealed primary hypothyroidism.
  
  
  METHODS
  the patient was started on levothyroxine with resolution of the mass effect.
  
  
  CONCLUSIONS
  primary hypothyroidism should be considered in the differential diagnosis of solid mass lesions of the pituitary gland. Examination of thyroid function in patients with sellar and suprasellar masses revealed by MRI may avoid unnecessary operations which can cause irreversible complications.
authors.affiliation: Pediatrics Unit, S.Chiara Hospital of Trento, Largo Medaglie d'Oro 9, 38122 Trento, Italy. roberto.franceschi@apss.tn.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Franceschi
authors.forename: Umberto
authors.initials: U
authors.lastname: Rozzanigo
authors.forename: Riccarda
authors.initials: R
authors.lastname: Failo
authors.forename: Maria
authors.initials: M
authors.lastname: Bellizzi
authors.forename: Annunziata
authors.initials: A
authors.lastname: Di Palma
mesh_terms: D002648:Child; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D010902:Pituitary Gland / Q000473:pathology*