title: [Changes in the cardiovascular system in selected endocrinopathies in children].
abstract: Hormones have influence on many tissues and organs including the cardiovascular system. This article analyzes fluctuations that happen in a child's cardiovascular system in selected endocrinopathies. We are pointing out the higher risk, in the course of diabetes, of development of arterial hypertension and atherosclerosis including participating mechanisms in their pathogenesis - disorders of the lipid metabolism, hiperinsulinaemia, insulin resistance or/and autonomic neuropathy. We are describing how the increased and reduced action of thyroid hormones on certain molecular pathways in the heart and vasculature causes relevant cardiovascular derangement. In the article, we are signaling also that the cardiovascular consequences of cortisol excess are elevation of blood pressure, obesity, hyperinsulinemia and/or dyslipidemia. This review analyzes the relationship of cortisol excess to these cardiovascular risk factors and to putative mechanisms for hypertension. In reference to clinical studies we are describing how the deficiency of the growth hormone is connected with a development of risk factors of cardiovascular diseases. In conclusion we underlined that early diagnosis and proper treatment of illnesses of the endocrine system can protect our pediatric patients from serious cardiac complications in later years.
authors.affiliation: Klinika Pediatrii, Pododdzialem Kardiologii Uniwersytetu Medycznego.
authors.forename: Kornel
authors.initials: K
authors.lastname: Semeran
authors.forename: Artur
authors.initials: A
authors.lastname: Bossowski
mesh_terms: D000307:Adrenal Gland Diseases / Q000150:complications / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000517:prevention & control; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology; D004700:Endocrine System Diseases / Q000150:complications* / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D006980:Hyperthyroidism / Q000150:complications / Q000503:physiopathology; D007037:Hypothyroidism / Q000150:complications / Q000503:physiopathology; D012307:Risk Factors
chemical_list: D006854:Hydrocortisone