title: Anterior interbody arthrodesis with percutaneous posterior pedicle fixation for degenerative conditions of the lumbar spine.
abstract: This is a retrospective case series to evaluate clinical variables, complications and outcome of 50 patients who underwent anterior lumbar interbody fusion (ALIF) supplemented with posterior percutaneous pedicle screw fixation for degenerative conditions of the lumbar spine. Twenty-four patients underwent single-level fusion and 26 patients had a two-level fusion for a total of 76 levels fused. The mean lengths of the anterior and posterior (including repositioning) portions of the procedure were 131 and 102 min, respectively. The mean estimated blood loss for the entire procedure was 288 ml. The overall adverse event rate was 12%. The mean VAS score for leg pain, VAS score for back pain and mean ODI all improved postoperatively. This study found that ALIF using allograft bone and rhBMP-2 combined with percutaneous pedicle screw fixation had a high fusion rate and a low incidence of perioperative complications. Patient outcomes showed significant improvements in back and leg pain and physical functioning.
authors.affiliation: Department of Orthopaedics, Thomas Jefferson University, Philadelphia, USA. greg.anderson@rothmaninstitute.com
authors.forename: D Greg
authors.initials: DG
authors.lastname: Anderson
authors.forename: Amirali
authors.initials: A
authors.lastname: Sayadipour
authors.forename: Kevin
authors.initials: K
authors.lastname: Shelby
authors.forename: Todd J
authors.initials: TJ
authors.lastname: Albert
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Vaccaro
authors.forename: Michael S
authors.initials: MS
authors.lastname: Weinstein
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D016268:Internal Fixators / Q000592:standards; D055959:Intervertebral Disc Degeneration / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation / Q000379:methods; D011183:Postoperative Complications / Q000453:epidemiology; D011859:Radiography; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D055009:Spondylosis / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*