title: Drug induced psoriasis.
abstract: Psoriasis is a chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery micaceous scale. While the exact causes of psoriasis have yet to be discovered, the immune system and genetics are known to play major roles in its development. Many external factors including infections, stress and medications may exacerbate psoriasis. Some of the most common medications know to trigger or worsen existing psoriasis include lithium, gold salts, beta blockers and antimalarials. Exacerbation of psoriasis due to the following medications has also been observed: adrenergic antagonists, interferon, gemfibrozil, iodine, digoxin and chlonidine. Having reviewed a variety of cases, we observed a relationship between certain medications and documented their involvement in exacerbating or inducing psoriasis.
authors.affiliation: Department of Dermatology and Venereology, University Hospital Center Zagreb, School of Medicine University of Zagreb, Croatia. visnja.milavecpuretic@gmail.com
authors.forename: Višnja
authors.initials: V
authors.lastname: Milavec-Puretić
authors.forename: Marko
authors.initials: M
authors.lastname: Mance
authors.forename: Romana
authors.initials: R
authors.lastname: Ceović
authors.forename: Jasna
authors.initials: J
authors.lastname: Lipozenčić
mesh_terms: D002908:Chronic Disease; D003875:Drug Eruptions / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D015994:Incidence; D011379:Prognosis; D011565:Psoriasis / Q000139:chemically induced* / Q000453:epidemiology* / Q000503:physiopathology; D018570:Risk Assessment; D012720:Severity of Illness Index