title: Clinical and radiographic features of solitary and cemento-osseous dysplasia-associated simple bone cysts.
abstract: The simple bone cyst (SBC) is a pseudocyst that can occur as a solitary entity in the jaws or may occur in association with cemento-osseous dysplasia (COD).
  
  
  OBJECTIVE
  The purpose of this study was to review the clinical and radiographic features of solitary and COD-associated SBCs.
  
  
  METHODS
  Archived imaging reports from the Special Procedures Clinic in Oral and Maxillofacial Radiology at the Faculty of Dentistry at the University of Toronto between 1 January 1989 and 31 December 2009 revealed 23 COD-associated SBCs and 68 solitary SBCs.
  
  
  RESULTS
  Almost all solitary and COD-associated SBCs were found in the mandible. Furthermore, 87.0% of COD-associated SBCs were found in females in their fifth decade of life (P < 0.001) while solitary SBCs were found in equal numbers in both sexes in their second decade of life (P < 0.005). COD-associated SBCs were also more likely to cause thinning of the endosteal cortex, bone expansion and scalloping of the superior border between teeth (all P < 0.001) than solitary SBCs that are classically described as having these characteristics. Finally, COD-associated SBC demonstrated a loss of lamina dura more often (P < 0.05) than solitary SBCs.
  
  
  CONCLUSIONS
  Knowledge of the sporadic association between COD and SBC and their potential radiographic appearances should prevent inappropriate treatment and management of these patients.
authors.affiliation: Faculty of Dentistry, the University of Toronto, ON, Canada.
authors.forename: J W
authors.initials: JW
authors.lastname: Chadwick
authors.forename: N A
authors.initials: NA
authors.lastname: Alsufyani
authors.forename: E W N
authors.initials: EW
authors.lastname: Lam
mesh_terms: D000293:Adolescent; D000328:Adult; D016723:Bone Remodeling; D002485:Cementoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D008439:Maxillary Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009631:Nonodontogenic Cysts / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D010019:Osteomyelitis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D055815:Young Adult