title: Copper-catalyzed α-amination of aliphatic aldehydes.
abstract: A highly efficient copper-catalyzed α-amination of aliphatic aldehydes for the synthesis of α-amino acetals using secondary amines with readily removable protecting groups as a nitrogen source was developed. This reaction can be operated under very mild conditions, affording the desired products in moderate to good yields.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637616.
authors.forename: Jie-Sheng
authors.initials: JS
authors.lastname: Tian
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D003300:Copper / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D003300:Copper