title: Transcriptional inhibition by DNA torsional stress.
abstract: Most genome transactions are favored by DNA (-) torsional stress, i.e., unconstrained unwinding or supercoiling of DNA. A question raised here is whether DNA (+) torsional stress, which precludes DNA unwinding, could also be relevant in gene regulation. Such DNA twist dynamics could be determined by chromatin architecture.
authors.affiliation: Instituto de Biologia Molecular de Barcelona; CSIC; Barcelona, Spain.
authors.forename: Joaquim
authors.initials: J
authors.lastname: Roca