title: Phospholipid binding lowers immunogenicity of human recombinant factor VIII in von Willebrand factor knockout mice.
authors.forename: D S
authors.initials: DS
authors.lastname: Pisal
authors.forename: S V
authors.initials: SV
authors.lastname: Balu-Iyer
mesh_terms: D000818:Animals; D019138:Antibodies, Blocking / Q000096:biosynthesis / Q000097:blood; D000917:Antibody Formation / Q000187:drug effects; D001665:Binding Sites / Q000276:immunology; D002478:Cells, Cultured; D000939:Epitopes / Q000378:metabolism; D005169:Factor VIII / Q000276:immunology / Q000378:metabolism* / Q000627:therapeutic use*; D006467:Hemophilia A / Q000097:blood / Q000188:drug therapy* / Q000235:genetics; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D010743:Phospholipids / Q000276:immunology / Q000378:metabolism*; D011485:Protein Binding; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D014841:von Willebrand Factor / Q000235:genetics
chemical_list: D019138:Antibodies, Blocking; D000939:Epitopes; D010743:Phospholipids; D014841:von Willebrand Factor; C427184:recombinant factor VIII SQ; D005169:Factor VIII