title: Coronary artery disease in patients undergoing valve replacement at a tertiary care cardiac centre.
abstract: OBJECTIVE
  To determine the prevalence of coronary artery disease in patients undergoing valve surgery at a tertiary care cardiac centre.
  
  
  METHODS
  The medical records of 144 consecutive patients who underwent mitral, aortic or dual (mitral and aortic) valve replacement surgery at the Tabba Heart Institue between January 2006 to December 2008 were retrospectively reviewed. All patients underwent coronary angiogram. Significant coronary artery disease (CAD) is defined as coronary stenosis of > or = 50%.
  
  
  RESULTS
  There were 74 (51.4%) males and 70 (48.6%) females in the study. The mean age was 51.64 +/- 11 years. Of all, 73 (50.7%) underwent mitral valve replacement, 47 (32.6%) had aortic and 24 (16.7%) had dual valve replacement. Out of 144 patients, 99 (68.8%) had < 50% coronary stenosis and remaining 45 (31.3%) had > or = 50% stenosis. In patients who had undergone mitral valve replacement (MVR), significant coronary disease was found in 32.9%, whereas in patients who had undergone aortic valve replacement (AVR) and dual valve replacement (DVR) the prevalence of coronary disease was 31.9% and 25% respectively.
  
  
  CONCLUSIONS
  Our results suggest that the overall prevalence of coronary artery disease in patients undergoing valve surgery in our population is comparable with prevalence reported in international data.
authors.affiliation: Tabba Heart Institute, Karachi.
authors.forename: Ayaz Hussain
authors.initials: AH
authors.lastname: Shaikh
authors.forename: Bashir
authors.initials: B
authors.lastname: Hanif
authors.forename: Khursheed
authors.initials: K
authors.lastname: Hasan
authors.forename: Amna
authors.initials: A
authors.lastname: Adil
authors.forename: Shahrukh
authors.initials: S
authors.lastname: Hashmani
authors.forename: Mohsin
authors.initials: M
authors.lastname: Raza
authors.forename: Hammad Ali
authors.initials: HA
authors.lastname: Qazi
authors.forename: Iqbal
authors.initials: I
authors.lastname: Mujtaba
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000601:surgery*; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000601:surgery; D004452:Echocardiography; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D012214:Rheumatic Heart Disease / Q000000981:diagnostic imaging / Q000453:epidemiology*; D012307:Risk Factors