title: Prospective randomized comparison of oral sodium phosphate and sennoside A+B calcium lavage for colonoscopy preparation.
abstract: OBJECTIVE
  The aim of this study is to assess 2 different bowel-cleansing agents.
  
  
  METHODS
  The patients were prospectively randomized to 2 arms of sodium phosphate versus Sennoside A+B calcium preparation. Laboratory assessment, body weight, height, and vital signs were obtained at baseline and before colonoscopy. A self-administered questionnaire was completed by the patients. The time taken to complete the colonoscopy and the segment of the colon examined were recorded.
  
  
  RESULTS
  The patients in the Sennoside A+B calcium group were more comfortable with the taste of the solution. Patients using sodium phosphate faced more nausea and significantly lower Ca levels and P values. The pulse rate was significantly higher in this group. Patients in the sennoside group had better grades of bowel cleansing in sigmoid and descending segments of the colon.
  
  
  CONCLUSIONS
  Sennoside A+B calcium is more effective in some of the colonic segmental cleansing, causes fewer changes on serum electrolyte levels, and is better tolerated.
authors.affiliation: Departments of Endoscopic Surgery, Maltepe University, Istanbul, Turkey. manukyanmanuk@yahoo.com
authors.forename: Manuk N
authors.initials: MN
authors.lastname: Manukyan
authors.forename: Kerem
authors.initials: K
authors.lastname: Tolan
authors.forename: Utku
authors.initials: U
authors.lastname: Severge
authors.forename: Wafi
authors.initials: W
authors.lastname: Attaallah
authors.forename: Abut
authors.initials: A
authors.lastname: Kebudi
authors.forename: Asim
authors.initials: A
authors.lastname: Cingi
mesh_terms: D000880:Anthraquinones / Q000008:administration & dosage / Q000627:therapeutic use*; D002400:Cathartics; D003113:Colonoscopy / Q000379:methods*; D004573:Electrolytes / Q000097:blood; D005260:Female; D005751:Gastric Lavage / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D012676:Senna Extract; D000081226:Sennosides; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D000880:Anthraquinones; D002400:Cathartics; D004573:Electrolytes; D010710:Phosphates; D000081226:Sennosides; D012676:Senna Extract; C018279:sodium phosphate