title: Calcific uremic arteriolopathy treated with cinacalcet, paricalcitol, and autologous growth factors.
abstract: BACKGROUND
  Calcific uremic arteriolopathy is an uncommon cutaneous ischemic necrotizing disease, most commonly associated with renal disease and hyperparathyroidism, bearing a high mortality rate.
  
  
  OBJECTIVE
  A case of a 57-year-old female renal patient with hyperparathyroidism who was successfully treated with combined paricalcitol and cinacalcet systemically, while autologous growth factors were locally applied, is herein presented.
  
  
  CONCLUSIONS
  The combination of cinacalcet and paricalcitol is a reliable alternative to parathyroidectomy in patients with calcific uremic arteriolopathy and hyperparathyroidism. Meticulous débridement of necrotic tissues is essential and application of autologous growth factors promotes healing.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Democritus University Hospital, Alexandrouplois, Greece. despoinakakagia@yahoo.com
authors.forename: Despoina
authors.initials: D
authors.lastname: Kakagia
authors.forename: Pelagia
authors.initials: P
authors.lastname: Kriki
authors.forename: Elias
authors.initials: E
authors.lastname: Thodis
authors.forename: Athanasios
authors.initials: A
authors.lastname: Roumeliotis
authors.forename: Vassilios
authors.initials: V
authors.lastname: Vargemezis
mesh_terms: D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002115:Calciphylaxis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D000069449:Cinacalcet; D003646:Debridement; D004872:Ergocalciferols / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000188:drug therapy*; D007676:Kidney Failure, Chronic / Q000150:complications; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging; D011859:Radiography; D014945:Wound Healing
chemical_list: D050071:Bone Density Conservation Agents; D004872:Ergocalciferols; D009281:Naphthalenes; C084656:paricalcitol; D000069449:Cinacalcet