title: The role of stem and circulating cells in cancer metastasis.
abstract: While many solid tumors have been reported to contain stem cell-like cells termed cancer stem cells, the case for a melanoma stem cell has been debated over the last few years. Herein, we summarize current knowledge of melanoma-initiating cells and provide an update on recently gained knowledge regarding cancer stem cells and melanoma.
authors.affiliation: Department of Dermatology, Epithelial Pipeline of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California, USA. ghadiallyr@derm.ucsf.edu
authors.forename: Ruby
authors.initials: R
authors.lastname: Ghadially
mesh_terms: D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D006801:Humans; D008545:Melanoma / Q000503:physiopathology* / Q000556:secondary*; D009362:Neoplasm Metastasis / Q000503:physiopathology; D009360:Neoplastic Cells, Circulating / Q000378:metabolism*; D014411:Neoplastic Stem Cells / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D000444:Aldehyde Dehydrogenase