title: Catalytic asymmetric aza-Darzens reaction with a vaulted biphenanthrol magnesium phosphate salt.
abstract: Conditions for a catalytic asymmetric aza-Darzens aziridine synthesis mediated by a vaulted biphenanthrol (VAPOL) magnesium phosphate salt is described. Using simple substrates, this methodology explores the scope and reactivity of a new magnesium catalyst for an aziridination reaction capable of building chirality and complexity simultaneously.
authors.affiliation: Department of Chemistry, University of South Florida, 4202 East Fowler Avenue CHE205A, Tampa, Florida 33620, United States.
authors.forename: Shawn E
authors.initials: SE
authors.lastname: Larson
authors.forename: Guilong
authors.initials: G
authors.lastname: Li
authors.forename: Gerald B
authors.initials: GB
authors.lastname: Rowland
authors.forename: Denise
authors.initials: D
authors.lastname: Junge
authors.forename: Rongcai
authors.initials: R
authors.lastname: Huang
authors.forename: H Lee
authors.initials: HL
authors.lastname: Woodcock
authors.forename: Jon C
authors.initials: JC
authors.lastname: Antilla
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D017616:Magnesium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010755:Organophosphates / Q000737:chemistry*; D010616:Phenanthrenes / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001372:Aza Compounds; D017616:Magnesium Compounds; D010755:Organophosphates; D010616:Phenanthrenes; D010710:Phosphates; C559805:biphenanthrol magnesium phosphate; C030781:magnesium phosphate