title: Reversible diffuse neurological deficits in systemic lupus erythematosus: report of a case.
abstract: We report a case of lupus presenting with focal as well as diffuse neurological deficits with intracranial and subarachnoid haemorrhages and diffuse hyperintense lesions in T2-weighted and fluid-attenuated inversion recovery images of brain magnetic resonance imaging proved by further investigation as demyelination, which completely recovered with intravenous methylprednisolone therapy. During the patient's hospital stay there was one episode of transient hypertensive episode lasting a few hours, promptly reverting to normal with low-dose ramipril therapy. Complete neurological and radiological recovery of such diffuse leucoencephalopathy-like central nervous system lesions has been rarely reported before.
authors.affiliation: Department of Medicine, Nil Ratan Sircar Medical College, Kolkata, India. drpartha73@gmail.com
authors.forename: P
authors.initials: P
authors.lastname: Chattopadhyay
authors.forename: D
authors.initials: D
authors.lastname: Dhua
authors.forename: Ca
authors.initials: C
authors.lastname: Philips
mesh_terms: D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D056784:Leukoencephalopathies / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D020945:Lupus Vasculitis, Central Nervous System / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000008:administration & dosage; D009422:Nervous System Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D055815:Young Adult
chemical_list: D008775:Methylprednisolone