title: Reductive conjugate addition of haloalkanes to enones to form silyl enol ethers.
abstract: A new method is presented for tandem reductive conjugate addition and silyl enol ether formation from cyclic and acyclic enones and enals in the presence of a Mn reductant, a Ni(terpyridine) catalyst, and a trialkylchlorosilane. The addition of secondary, tertiary, and hindered primary haloalkanes is demonstrated. Preliminary studies on the mechanism show that the intermediacy of L1(Ni)(η(3)-1-triethylsilyloxyalkenyl)X or in-situ-formed RMnX is unlikely.
authors.affiliation: Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.
authors.forename: Ruja
authors.initials: R
authors.lastname: Shrestha
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Weix