title: Vascular injury following accidental intra-arterial injection of clindamycin: adverse drug reaction report.
abstract: Clindamycin in a commonly used antibiotic, considered safe for oral, intravenous and intra-arterial use. We present a case of a patient that received an inadvertent injection clindamycin 600 mg in 4 mL through a radial arterial line. The patient presented signs and symptoms of vascular occlusion and despite aggressive pharmacological and medical treatment developed massive and severe tissue injury.
authors.affiliation: Department of Anesthesiology, Rambam Health Care Campus, Haifa, Israel. amit.lehavi@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Lehavi
authors.forename: A
authors.initials: A
authors.lastname: Sandler
authors.forename: A
authors.initials: A
authors.lastname: Netzer
authors.forename: Y Shai
authors.initials: YS
authors.lastname: Katz
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002981:Clindamycin / Q000008:administration & dosage / Q000009:adverse effects*; D005385:Fingers / Q000098:blood supply; D006801:Humans; D007261:Infusions, Intra-Arterial; D007511:Ischemia / Q000139:chemically induced / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D010146:Pain / Q000209:etiology; D012039:Regional Blood Flow / Q000502:physiology; D057772:Vascular System Injuries / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin