title: Statins: a role in infected critically ill patients?
abstract: Terblanche and colleagues add to the ongoing controversy over the role, if any, for statins in patients with sepsis. The authors note that statins fail to prevent progression to organ dysfunction in critically ill patients. However, like most publications, the study is retrospective and stimulates the controversy but fails to resolve it. The time has come for robust randomized controlled clinical trials.
authors.affiliation: Pulmonary and Critical Care Medicine, University of Virginia, Box 800793, Charlottesville, VA 22908, USA. truwit@virginia.edu.
authors.forename: Jonathon Dean
authors.initials: JD
authors.lastname: Truwit
mesh_terms: D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D008297:Male; D009102:Multiple Organ Failure / Q000517:prevention & control*; D012121:Respiration, Artificial
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors