title: New antifungal xanthones from the seeds of Rhus coriaria L.
abstract: Phytochemical investigations of the ethanolic extract of the seeds of Rhus coriaria L. (Anacardiaceae) led to the identification of four new xanthones, characterized as 2,3-dihydroxy-7-methyl xanthone (1), 2,3,6-trihydroxy-7-hydroxymethylene xanthone-1-carboxylic acid (2), 2-methoxy-4-hydroxy-7-methyl-3-O-beta-D-glucopyranosyl xanthone-1,8-dicarboxylic acid (4), and 2-hydroxy-7-hydroxymethylene xanthone-1,8-dicarboxylic acid 3-O-beta-D-glucopyranosyl-(2'-->3")-3"-O-stigmast-5-ene (5), along with the known steroidal glucoside beta-sitosterol-beta-D-glucoside (3). The structures of the isolated compounds have been identified on the basis of spectral data analysis and chemical reactions. All xanthones were active against Aspergillus flavus.
authors.affiliation: Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi-1100 62, India.
authors.forename: Onkar
authors.initials: O
authors.lastname: Singh
authors.forename: Mohammed
authors.initials: M
authors.lastname: Ali
authors.forename: Nida
authors.initials: N
authors.lastname: Akhtar
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification*; D029045:Rhus / Q000196:embryology*; D012639:Seeds / Q000737:chemistry*; D044004:Xanthones / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D044004:Xanthones