title: Green tea and bone health: Evidence from laboratory studies.
abstract: Osteoporosis is a major health problem in the elderly. Epidemiological evidence has shown an association between tea consumption and the prevention of bone loss in the elderly population. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures. This review describes the effect of green tea with its bioactive components on bone health with an emphasis on the following: (i) the etiology of osteoporosis, (ii) evidence of osteo-protective impacts of green tea on bone mass and microarchitecture in various bone loss models in which induced by aging, sex hormone deficiency, and chronic inflammation, (iii) discussion of impacts of green tea on bone mass in two obesity models, (iv) observation of short-term green tea supplementation given to postmenopausal women with low bone mass, (v) possible mechanisms for the osteo-protective effects of green tea bioactive compounds, and (vi) a summary and future research direction of green tea and bone health.
authors.affiliation: Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430-9097, USA. leslie.shen@ttuhsc.edu
authors.forename: Chwan-Li
authors.initials: CL
authors.lastname: Shen
authors.forename: James K
authors.initials: JK
authors.lastname: Yeh
authors.forename: Jay J
authors.initials: JJ
authors.lastname: Cao
authors.forename: Ming-Chien
authors.initials: MC
authors.lastname: Chyu
authors.forename: Jia-Sheng
authors.initials: JS
authors.lastname: Wang
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects*; D001842:Bone and Bones / Q000187:drug effects*; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D058866:Osteoporotic Fractures / Q000517:prevention & control*; D013662:Tea
chemical_list: D013662:Tea