title: Pure small cell carcinoma of the prostate: a case report and literature review.
abstract: Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.
authors.affiliation: Radiation Therapy Department, University Hospital of Ioannina, Ioannina, Greece.
authors.forename: Antonio
authors.initials: A
authors.lastname: Capizzello
authors.forename: Evangelia
authors.initials: E
authors.lastname: Peponi
authors.forename: Nafsika
authors.initials: N
authors.lastname: Simou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Ntaskagiannis
authors.forename: Ifigenia
authors.initials: I
authors.lastname: Tasiou
authors.forename: Sevasti
authors.initials: S
authors.lastname: Kamina
authors.forename: Periklis
authors.initials: P
authors.lastname: Tsekeris