title: Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication.
abstract: A high rate of resistance (49.5 to 72.7%) to amoxicillin (AMX) was observed in Helicobacter pylori after two or three unsuccessful eradication attempts. Unsuccessful eradication regimens significantly increase resistance to not only clarithromycin (CLR) and metronidazole (MNZ) but also AMX.
authors.affiliation: Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nishizawa
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Suzuki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tsugawa
authors.forename: Hiroe
authors.initials: H
authors.lastname: Muraoka
authors.forename: Juntaro
authors.initials: J
authors.lastname: Matsuzaki
authors.forename: Kenro
authors.initials: K
authors.lastname: Hirata
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ikeda
authors.forename: Masahiko
authors.initials: M
authors.lastname: Takahashi
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hibi
mesh_terms: D000658:Amoxicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin