title: The impact of OAB on sexual health in men and women: results from EpiLUTS.
abstract: BACKGROUND
  Prior research suggests that overactive bladder (OAB) is common and adversely affects sexuality in both men and women. However, more data are needed from population-based studies to evaluate the impact OAB on sexual health.
  
  
  OBJECTIVE
  To describe sexual health outcomes in men and women with continent and incontinent OAB (C-OAB, I-OAB) compared to those with no/minimal urinary symptoms (NMS) and to evaluate correlates of decreased sexual activity and enjoyment in men and women, and correlates of erectile dysfunction (ED), ejaculatory dysfunction (EjD), and premature ejaculation (PE) in men.
  
  
  METHODS
  A cross-sectional, population-representative survey was conducted via the Internet in the United Kingdom, Sweden, and United States. OAB was assessed via a questionnaire based on current International Continence Society definitions. Descriptive statistics were used to compare outcomes for those with I-OAB, C-OAB and NMS, and logistic regressions were used to evaluate predictors of sexual functioning.
  
  
  METHODS
  Participants responding to the sexual health portion of the survey were asked questions about sexual activity and satisfaction. Other outcomes included two domains from the Abbreviated Sexual Function Questionnaire, the erectile function domain of the International Index of Erectile Function, and questions assessing EjD and PE.
  
  
  RESULTS
  Survey response was 59.2%; 6,326 men and 8,085 women participated in the sexual health portion of the survey. Across outcomes, I-OAB and C-OAB were associated with worse sexual health as compared to those with NMS. Logistic regressions showed that those with I-OAB and C-OAB were significantly (P<0.0001) more likely to report diminished sexual activity and enjoyment of sex. I-OAB and C-OAB were also significant predictors of ED and EjD in men, but not PE.
  
  
  CONCLUSIONS
  The impact of OAB is evident across domains of sexual health in both men and women. Sexual health should be assessed in men and women presenting with OAB.
authors.affiliation: United BioSource Corporation, Bethesda, MD, USA. karin.coyne@unitedbiosource.com
authors.forename: Karin S
authors.initials: KS
authors.lastname: Coyne
authors.forename: Chris C
authors.initials: CC
authors.lastname: Sexton
authors.forename: Christine
authors.initials: C
authors.lastname: Thompson
authors.forename: Zoe S
authors.initials: ZS
authors.lastname: Kopp
authors.forename: Ian
authors.initials: I
authors.lastname: Milsom
authors.forename: Steven A
authors.initials: SA
authors.lastname: Kaplan
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D004542:Ejaculation; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D020407:Internet; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D012725:Sexual Behavior; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology* / Q000523:psychology; D020018:Sexual Dysfunctions, Psychological / Q000453:epidemiology* / Q000523:psychology*; D011795:Surveys and Questionnaires; D013548:Sweden; D006113:United Kingdom; D014481:United States; D053201:Urinary Bladder, Overactive / Q000453:epidemiology* / Q000523:psychology*; D014549:Urinary Incontinence / Q000453:epidemiology* / Q000523:psychology*