title: Still Struggling: characteristics of youth with OCD who are partial responders to medication treatment.
abstract: The primary aim of this paper is to examine the characteristics of a large sample of youth with OCD who are partial responders (i.e., still have clinically significant symptoms) to serotonin reuptake inhibitor (SRI) medication. The sample will be described with regard to: demographics, treatment history, OCD symptoms/severity, family history and parental psychopathology, comorbidity, and global and family functioning. The sample includes 124 youth with OCD ranging in age from 7 to 17 with a primary diagnosis of OCD and a partial response to an SRI medication. The youth are a predominantly older (age 12 and over), Caucasian, middle to upper income group who had received significant past treatment. Key findings include moderate to severe OCD symptoms, high ratings of global impairment, and significant comorbidity, despite partial response to an adequate medication trial. Considerations regarding generalizability of the sample and limitations of the study are discussed.
authors.affiliation: Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA. jfreeman@lifespan.org
authors.forename: J
authors.initials: J
authors.lastname: Freeman
authors.forename: J
authors.initials: J
authors.lastname: Sapyta
authors.forename: A
authors.initials: A
authors.lastname: Garcia
authors.forename: D
authors.initials: D
authors.lastname: Fitzgerald
authors.forename: M
authors.initials: M
authors.lastname: Khanna
authors.forename: M
authors.initials: M
authors.lastname: Choate-Summers
authors.forename: P
authors.initials: P
authors.lastname: Moore
authors.forename: A
authors.initials: A
authors.lastname: Chrisman
authors.forename: N
authors.initials: N
authors.lastname: Haff
authors.forename: A
authors.initials: A
authors.lastname: Naeem
authors.forename: J
authors.initials: J
authors.lastname: March
authors.forename: M
authors.initials: M
authors.lastname: Franklin
mesh_terms: D000293:Adolescent; D002648:Child; D015928:Cognitive Behavioral Therapy; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000523:psychology*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors