title: Discrete papular dermal mucinosis with Hashimoto thyroiditis: a case report.
abstract: The cutaneous focal mucinoses are a group of connective tissue disorders characterized by deposition of mucin found either focally or diffusely in the dermis. A 47-year-old woman presented with asymptomatic flesh-colored papules on the neck, inguinal area, intergluteal area, vulvar area, and extremities of 5 months' duration. There was no history of preceding trauma or insect bites. The patient had undergone a subtotal thyroidectomy 21 years prior but had not used any thyroid medication before she was referred to our clinic. Thyroid ultrasonography was consistent with Hashimoto thyroiditis. During dermatologic examination, flesh-colored, well-defined, smooth papules that measured approximately 1.5 x 1 cm in size on the genital region, fingers, face, and scalp were seen. Histopathologic examination of a lesional biopsy revealed no abnormalities in the epidermis. Alcian blue staining showed that abundant deposits of dermal mucin had replaced collagen in the dermis.
authors.affiliation: Dermatology Department, Faculty of Medicine, Ege University, Bomova, Izmir, Turkey. iertam@yahoo.com
authors.forename: Ilgen
authors.initials: I
authors.lastname: Ertam
authors.forename: Nezih
authors.initials: N
authors.lastname: Karaca
authors.forename: Can
authors.initials: C
authors.lastname: Ceylan
authors.forename: Alican
authors.initials: A
authors.lastname: Kazandi
authors.forename: Sibel
authors.initials: S
authors.lastname: Alper
mesh_terms: D000423:Alcian Blue; D001706:Biopsy; D003094:Collagen / Q000378:metabolism; D020405:Dermis / Q000378:metabolism; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D053718:Scleromyxedema / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D009077:Mucins; D003094:Collagen; D000423:Alcian Blue