title: A discovery 70 years in the making: characterization of the Rose rosette virus.
abstract: Rose rosette was first described in the early 1940s and it has emerged as one of the most devastating diseases of roses. Although it has been 70 years since the disease description, the rosette agent is yet to be characterized. In this communication, we identify and characterize the putative causal agent of the disease, a negative-sense RNA virus and new member of the genus Emaravirus. The virus was detected in 84/84 rose rosette-affected plants collected from the eastern half of the USA, but not in any of 30 symptomless plants tested. The strong correlation between virus and disease is a good indication that the virus, provisionally named Rose rosette virus, is the causal agent of the disease. Diversity studies using two virus proteins, p3 and p4, demonstrated that the virus has low diversity between isolates as they share nucleotide identities ranging from 97 to 99%.
authors.affiliation: Department of Plant Pathology, Division of Agriculture, University of Arkansas, Fayetteville, AR 72701, USA.
authors.forename: Alma G
authors.initials: AG
authors.lastname: Laney
authors.affiliation: USDA-ARS Horticultural Crops Research Laboratory, Corvallis, OR 97330, USA.
authors.forename: Karen E
authors.initials: KE
authors.lastname: Keller
authors.affiliation: Department of Botany and Plant Pathology, Oregon State University, OR 97331, USA.|USDA-ARS Horticultural Crops Research Laboratory, Corvallis, OR 97330, USA.
authors.forename: Robert R
authors.initials: RR
authors.lastname: Martin
authors.affiliation: Department of Plant Pathology, Division of Agriculture, University of Arkansas, Fayetteville, AR 72701, USA.
authors.forename: Ioannis E
authors.initials: IE
authors.lastname: Tzanetakis
mesh_terms: D016679:Genome, Viral; D049673:History, 20th Century; D049674:History, 21st Century; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D010802:Phylogeny; D010935:Plant Diseases / Q000266:history* / Q000821:virology*; D012328:RNA Viruses / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D027826:Rosa / Q000821:virology*; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D014764:Viral Proteins