title: Fluorescence-enhanced potassium ions detection based on inherent quenching ability of deoxyguanosines and K(+)-induced conformational transition of G-rich ssDNA from duplex to G-quadruplex structures.
abstract: Herein, we develop a novel single fluorophore-labeled double-stranded oligonucleotide (OND) probe for rapid fluorescence-enhanced K(+) detection, based on an inherent quenching ability of guanine bases and G-rich OND conformation transition from duplex to G-quadruplex. This probe presents high sensitivity and good selectivity for the detection of K(+), and the assay process is simple and fast.
authors.affiliation: State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China.
authors.forename: Yingwei
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jingqi
authors.initials: J
authors.lastname: Tian
authors.forename: Junfeng
authors.initials: J
authors.lastname: Zhai
authors.forename: Yonglan
authors.initials: Y
authors.lastname: Luo
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Hailong
authors.initials: H
authors.lastname: Li
authors.forename: Xuping
authors.initials: X
authors.lastname: Sun
mesh_terms: D004277:DNA, Single-Stranded / Q000737:chemistry*; D003849:Deoxyguanosine / Q000737:chemistry*; D005453:Fluorescence; D054856:G-Quadruplexes; D007477:Ions / Q000032:analysis; D015345:Oligonucleotide Probes / Q000737:chemistry*; D011188:Potassium / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D004277:DNA, Single-Stranded; D007477:Ions; D015345:Oligonucleotide Probes; D003849:Deoxyguanosine; D011188:Potassium