title: [The potential role of SPECT/CT in the preoperative detection of sentinel lymph nodes in breast cancer].
abstract: Regional lymph node status is the most important prognostic factor in breast cancer. Sentinel lymph node biopsy is the standard method of axillary staging in early breast cancer patients with clinically negative nodes. Preoperative lymphoscintigraphy might support refining biopsy findings by determining the number and location of sentinel lymph nodes. In aged or overweight patients, in the presence of atypical or extra-axillary lymphatic drainage, non-visualized lymph nodes, or sentinel lymph nodes close to the isotope injection site, detection could be aided by a new, hybrid imaging tool: the single-photon emission computed tomography combined with computed tomography (3D SPECT/CT). For the first time in Hungarian language, authors overview the literature: all 14 English-language articles on the implementation of 3D SPECT/CT in sentinel lymph node detection in breast cancer are included. It is concluded that 3D SPECT/CT increases the success rate and quality of preoperative sentinel node identification, and is capable of providing a more accurate staging of breast cancer patients in routine clinical practice.
authors.affiliation: Országos Onkológiai Intézet Általános és Mellkassebészeti Osztály Budapest Ráth György u. 7-9. 1122. matraidok@freemail.hu
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Mátrai
authors.forename: László
authors.initials: L
authors.lastname: Tóth
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Saeki
authors.forename: István
authors.initials: I
authors.lastname: Sinkovics
authors.forename: Mária
authors.initials: M
authors.lastname: Godény
authors.forename: Hideki
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Mária
authors.initials: M
authors.lastname: Bidlek
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bartal
authors.forename: Akos
authors.initials: A
authors.lastname: Sávolt
authors.forename: Bence
authors.initials: B
authors.lastname: Dorogi
authors.forename: Miklós
authors.initials: M
authors.lastname: Kásler
mesh_terms: D001365:Axilla; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000601:surgery; D009367:Neoplasm Staging; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D019275:Radiopharmaceuticals; D012211:Rhenium; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D017556:Technetium Compounds; D013668:Technetium Tc 99m Aggregated Albumin; D013671:Technetium Tc 99m Sulfur Colloid; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D017556:Technetium Compounds; D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid; C030576:technetium Tc 99m rhenium colloid; C026177:technetium phytate; D013671:Technetium Tc 99m Sulfur Colloid; D012211:Rhenium; D010833:Phytic Acid