title: Nanomaterials as in vivo sensors.
abstract: The methods of monitoring cellular processes are either snap-shots or based on in vitro measurements. Nanomaterials have specific advantages to be excellent probes to monitor in vivo processes. In this study we have demonstrated that attachment of neurotransmitter, serotonin to iron oxide nanoparticles brings about enhanced contrast in cells that express the receptor for serotonin specifically.
authors.affiliation: Centre for Cellular and Molecular Biology, (Council of Scientific and Industrial Research, India), Hyderabad 500007, India.
authors.forename: Manswita
authors.initials: M
authors.lastname: Nag
authors.forename: Anant
authors.initials: A
authors.lastname: Patel
authors.forename: N Madhusudhana
authors.initials: NM
authors.lastname: Rao
mesh_terms: D001681:Biological Assay / Q000379:methods*; D045744:Cell Line, Tumor; D003287:Contrast Media / Q000138:chemical synthesis / Q000493:pharmacokinetics; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry; D057054:Molecular Imaging / Q000379:methods*; D009447:Neuroblastoma / Q000378:metabolism / Q000473:pathology*; D012701:Serotonin / Q000737:chemistry / Q000493:pharmacokinetics*
chemical_list: D003287:Contrast Media; D058185:Magnetite Nanoparticles; D012701:Serotonin