title: Detection and prognostic impact of micrometastasis in colorectal cancer.
abstract: Review of literature was performed on studies with prognostic impact of micrometastasis in colorectal cancer. Among 16 studies included, micrometastasis was detected in 26.5% of patients. Most analysis revealed that micrometastasis carries a poorer prognosis compared to node negative disease (NND). The results of those studies were compared with our pilot study of 109 patients with colon cancer, showing improved prognosis of micrometastasis after being upstaged and treated with chemotherapy when compared with NND.
authors.affiliation: Department of Surgical Oncology, McLaren Regional Medical Center, Michigan State University, Flint, Michigan, USA.
authors.forename: Saad
authors.initials: S
authors.lastname: Sirop
authors.forename: Mohammed
authors.initials: M
authors.lastname: Kanaan
authors.forename: Alpesh
authors.initials: A
authors.lastname: Korant
authors.forename: David
authors.initials: D
authors.lastname: Wiese
authors.forename: David
authors.initials: D
authors.lastname: Eilender
authors.forename: Sunil
authors.initials: S
authors.lastname: Nagpal
authors.forename: Madan
authors.initials: M
authors.lastname: Arora
authors.forename: Trevor
authors.initials: T
authors.lastname: Singh
authors.forename: Sukamal
authors.initials: S
authors.lastname: Saha
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009367:Neoplasm Staging; D021701:Sentinel Lymph Node Biopsy; D016019:Survival Analysis; D016896:Treatment Outcome