title: A novel autologous scaffold for diced-cartilage grafts in dorsal augmentation rhinoplasty.
abstract: BACKGROUND
  Diced-cartilage grafts have been used for dorsal nasal augmentation for several years with good results. However, compounds such as Surgicel and temporalis fascia used as a wrap have inherent problems associated with them, predominantly inflammation and graft resorption. An autologous carrier could provide stabilization of cartilage grafts while avoiding the complications seen with earlier techniques.
  
  
  METHODS
  In our patients, a malleable construct was used for dorsal nasal augmentation in which autologous diced-cartilage grafts were stabilized with autologous tissue glue (ATG) created from platelet-rich plasma (platelet gel) and platelet-poor plasma (fibrin glue).
  
  
  RESULTS
  A prospective analysis of 68 patients, who underwent dorsal nasal augmentation utilizing ATG and diced-cartilage grafts between 2005 and 2008, were included in the study. Although there was notable maintenance of the dorsal height, no complications occurred that required explantation over a mean follow-up of 15 months.
  
  
  CONCLUSIONS
  The use of ATG to stabilize diced-cartilage grafts is a safe, reliable technique for dorsal nasal augmentation. The platelet gel provides growth factors while the fibrin glue creates a scaffold that allows stabilization and diffusion of nutrients to the cartilage graft.
authors.affiliation: Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Jamal M
authors.initials: JM
authors.lastname: Bullocks
authors.forename: Anthony
authors.initials: A
authors.lastname: Echo
authors.forename: Gerardo
authors.initials: G
authors.lastname: Guerra
authors.forename: Samuel
authors.initials: S
authors.lastname: Stal
authors.forename: Eser
authors.initials: E
authors.lastname: Yuksel
mesh_terms: D000293:Adolescent; D000328:Adult; D002356:Cartilage / Q000637:transplantation*; D005260:Female; D006801:Humans; D009666:Nose / Q000002:abnormalities* / Q000601:surgery; D010949:Plasma; D012225:Rhinoplasty / Q000379:methods*; D012272:Ribs / Q000637:transplantation; D014014:Tissue Adhesives; D054457:Tissue Scaffolds; D016378:Tissue Transplantation; D020858:Tissue and Organ Harvesting; D014182:Transplantation, Autologous; D055815:Young Adult
chemical_list: D014014:Tissue Adhesives