title: [Chronically progressive occlusive disease of intestinal arteries - short overview from a vascular surgical perspective].
abstract: BACKGROUND
  Intestinal ischaemia is quite rare among the cardiovascular diseases. However, it is increasingly diagnosed. The aim of this selective but representative short overview is to assess the impact of intestinal ischaemia in vascular and visceral medicine from a vascularsurgical perspective.
  
  
  METHODS
  A literature search and selection in relevant online services of the medical scientific literature was performed, in particular, of the last decade on the competent management of intestinal ischaemia combined with the clinical expertise obtained in daily vascular surgical practice including didactically prepared demonstrable cases / case reports related to typical / specific clinical problems and situations.
  
  
  CONCLUSIONS
  Although the superior mesenteric artery (SMA) is most frequently responsible for the clinical presentation, usually 2 or 3  major arterial trunks are involved for a relevant clinical symptomatology. These disorders of the intestinal circulation are most frequently caused by progressive atherosclerotic occlusive disease. In chronic progressive disease, the visceral arteries show the ability to enlarge typical collateral circulation pathways, which may not always lead to a complete compensation. With a degree of stenosis of more than 70 %, mesenteric ischaemic pain and physical prostration are the major clinical findings. Intestinal infarction with a mortality rate of 60-80 % is the endpoint of the chronically progressive intestinal ischaemia. There-fore, an urgent medical treatment is highly required. CT angiography is the diagnostic procedure of choice in patients with suspected chronic intestinal ischaemia. Mesenteric angiography is subject to specific questions and / or to endovascular arteriographic treatment. Duplex scanning has been advocated as a non-invasive method of pre- and post-interventional screening. Treatment is indicated in symptomatic intestinal vascular disease. Due to the high morbidity of the majority of patients and the enormous invasivity associated with conventional surgery, arteriographic intervention is the treatment of choice, even though quality improvement is required. Surgical reconstructions are highly standardised and should be associated with perioperative mortality less than 3 %. We recommended the reconstruction of 2  vessels, for which antegrade supracoeliacal revascularisation techniques are favourable. In (threatening) septic conditions, autologous reconstructions are required. Intestinal infarction is the most serious complication of all visceral revascularisations. In recurrent occlusions of visceral arteries, it is recommended to favour and finally use a different therapeutic modality. Post-therapeutic care includes second-look operation as well as clinical examination and diagnostic imaging. Antithrombotic therapy should be initiated. The further screening of patients after intestinal revascularisation should be performed by duplex scanning.
  
  
  CONCLUSIONS
  Chronically progressive occlusive disease of intestinal arteries is considered as a complex disease with challenging diagnostic and therapeutic management, in which an interdisciplinary, partly finding- and stage-dependent (also with regard to the frequency and recurrency of the specific local finding) sequential therapeutic approach (e. g., endovascular vs. open procedure; interventionalist / endovascular specialist / vascular surgeon) becomes more and more relevant requiring a competent center of vascular medicine.
authors.affiliation: Klinik für Gefäßchirurgie, Helios-Klinikum, Krefeld, Deutschland. bernd.luther@helios-kliniken.de
authors.forename: B
authors.initials: B
authors.lastname: Luther
authors.forename: F
authors.initials: F
authors.lastname: Meyer
authors.forename: T
authors.initials: T
authors.lastname: Nowak
authors.forename: U
authors.initials: U
authors.lastname: Kempf
authors.forename: H
authors.initials: H
authors.lastname: Krasniqi
mesh_terms: D000792:Angiography; D002908:Chronic Disease; D003097:Collateral Circulation / Q000502:physiology; D003299:Cooperative Behavior; D018450:Disease Progression; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D007238:Infarction / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D033183:Interdisciplinary Communication; D007422:Intestines / Q000098:blood supply*; D007511:Ischemia / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D017538:Mesenteric Artery, Superior / Q000601:surgery; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D005343:Fibrinolytic Agents