title: [Investigation of Tahyna virus infection among unknown fever cases in Xinjiang, China].
abstract: To investigate the infection status and the spatial distribution of Tahyna virus infection among unknown fever cases in Xinjiang, China. Sera samples of unknown fever cases from Kashi in southern Xin-jiang and Yili in northern Xinjiang were tested against Tahyna virus by IFA. Partial positive cases were tested against Tahyna virus/Snowshoe hare virus/Inkoo virus parrelled. Finally, 742 sera samples of unknown fever cases were collected from Kashi, Southern Xinjiang in 2007-2008, the positive rate of IgM antibody against Tahyna virus was 5.3%, the positive rate of IgG antibody against Tahyna virus was 18.3%. 222 sera samples of unknown fever cases were collected from Yili, Northern Xinjiang in 2008, no positive case of IgM antibody against Tahyna was found. 10 cases showed antibody neutralization against Tahyna virus by plaque reduction neutralization test. Our results demonstrate that there is current infection and past infection of Tahyna virus among Southern Xinjiang residents.
authors.affiliation: State Key Laboratory for Infectious Disease Control and Prevention, Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, China. Liflit@hotmail.com
authors.forename: Zhi
authors.initials: Z
authors.lastname: Lv
authors.forename: Shi-hong
authors.initials: SH
authors.lastname: Fu
authors.forename: Feng-tian
authors.initials: FT
authors.lastname: Wang
authors.forename: Olga L
authors.initials: OL
authors.lastname: Kosoy
authors.forename: Roger S
authors.initials: RS
authors.lastname: Nasci
authors.forename: Guo-dong
authors.initials: GD
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D002141:Encephalitis Virus, California / Q000276:immunology / Q000502:physiology*; D004670:Encephalitis, California / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D005260:Female; D005334:Fever / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M