title: [Neuromediator systems in the brain of rats in alcohol abstinence syndrome].
abstract: The content of key neuromediators in the brain cortex, brain stem, and thalamus was studied in rats under conditions of alcohol abstinence syndrome. At the peak of the abstinence syndrome manifestation (one day), these parts of the brain were characterized by an increase in the level of dopamine, which was normalized by the end of a one-week period of abstinence. On the third day of abstinence, there was a decrease in the content of noradrenaline in the brain stem on the background of normalization of the neurotransmission processes in the brain cortex and thalamus. Upon a one-week abstinence, the content of noradrenaline in the brain stem and cortex changed in the opposite directions.
authors.forename: S V
authors.initials: SV
authors.lastname: Lelevich
authors.forename: E M
authors.initials: EM
authors.lastname: Doroshenko
mesh_terms: D000435:Alcoholic Intoxication / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D008297:Male; D018377:Neurotransmitter Agents / Q000378:metabolism*; D051381:Rats; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*; D013788:Thalamus / Q000378:metabolism
chemical_list: D000596:Amino Acids; D015306:Biogenic Monoamines; D018377:Neurotransmitter Agents