title: [Human herpesvirus-6 and human herpesvirus-7 (HHV-6, HHV-7)].
abstract: human herpesvirus 6 (HHV-6) is the major causative agent of exanthem subitum which is one of popular diseases in infant, and establishes latent infections in adults of more than 90%. Recently, the encephalitis caused by reactivated- HHV-6 has been shown in patients after transplantation. In addition, the relationship HHV-6 and drug-induced hypersensitivity syndrome has also been reported. human herpesvirus 7 (HHV-7) was isolated from the stimulated-peripheral blood lymphocytes of a healthy individual, and also causes exanthema subitum. Both viruses are related viruses which belong to betaherpesvirus subfamily, and replicate and produce progeny viruses in T cells.
authors.affiliation: Division of Virology and vaccinology, National Institute of Biomedical Innovation.
authors.forename: Huamin
authors.initials: H
authors.lastname: Tang
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Sadaoka
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Mori
mesh_terms: D000328:Adult; D005077:Exanthema Subitum / Q000175:diagnosis / Q000628:therapy / Q000635:transmission / Q000821:virology; D015967:Gene Expression Regulation, Viral; D005814:Genes, Viral / Q000235:genetics; D016679:Genome, Viral / Q000235:genetics; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology; D016199:Herpesvirus 7, Human / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D007223:Infant; D051916:Membrane Cofactor Protein / Q000502:physiology; D011991:Receptors, Virus / Q000502:physiology; D013601:T-Lymphocytes / Q000821:virology; D014771:Virion / Q000472:pathogenicity; D014775:Virus Activation; D016662:Virus Integration; D017735:Virus Latency
chemical_list: D051916:Membrane Cofactor Protein; D011991:Receptors, Virus