title: Global oral health inequalities: task group--periodontal disease.
abstract: Periodontal diseases constitute one of the major global oral health burdens, and periodontitis remains a major cause of tooth loss in adults worldwide. The World Health Organization recently reported that severe periodontitis exists in 5-20% of adult populations, and most children and adolescents exhibit signs of gingivitis. Likely reasons to account for these prevalent diseases include genetic, epigenetic, and environmental risk factors, as well as individual and socio-economic determinants. Currently, there are fundamental gaps in knowledge of such fundamental issues as the mechanisms of initiation and progression of periodontal diseases, which are undefined; inability to identify high-risk forms of gingivitis that progress to periodontitis; lack of evidence on how to prevent the diseases effectively; inability to detect disease activity and predict treatment efficacy; and limited information on the effects of integration of periodontal health as a part of the health care program designed to promote general health and prevent chronic diseases. In the present report, 12 basic, translational, and applied research areas have been proposed to address the issue of global periodontal health inequality. We believe that the oral health burden caused by periodontal diseases could be relieved significantly in the near future through an effective global collaboration.
authors.affiliation: Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China. ljjin@hkucc.hku.hk
authors.forename: L J
authors.initials: LJ
authors.lastname: Jin
authors.forename: G C
authors.initials: GC
authors.lastname: Armitage
authors.forename: B
authors.initials: B
authors.lastname: Klinge
authors.forename: N P
authors.initials: NP
authors.lastname: Lang
authors.forename: M
authors.initials: M
authors.lastname: Tonetti
authors.forename: R C
authors.initials: RC
authors.lastname: Williams
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002908:Chronic Disease; D018865:Dental Research; D014943:Global Health; D006292:Health Priorities; D006297:Health Services Accessibility; D054624:Health Status Disparities; D006801:Humans; D007391:International Cooperation; D009909:Oral Health; D010510:Periodontal Diseases / Q000150:complications / Q000453:epidemiology*; D012959:Socioeconomic Factors