title: Bioinspired catalyst design and artificial metalloenzymes.
abstract: Many bioinspired transition-metal catalysts have been developed over the recent years. In this review the progress in the design and application of ligand systems based on peptides and DNA and the development of artificial metalloenzymes are reviewed with a particular emphasis on the combination of phosphane ligands with powerful molecular recognition and shape selectivity of biomolecules. The various approaches for the assembly of these catalytic systems will be highlighted, and the possibilities that the use of the building blocks of Nature provide for catalyst optimisation strategies are discussed.
authors.affiliation: School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST, UK.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Deuss
authors.forename: René
authors.initials: R
authors.lastname: den Heeten
authors.forename: Wouter
authors.initials: W
authors.lastname: Laan
authors.forename: Paul C J
authors.initials: PC
authors.lastname: Kamer
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D021881:DNA, Catalytic / Q000737:chemistry*; D008024:Ligands; D008667:Metalloproteins / Q000737:chemistry*; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry*; D013237:Stereoisomerism; D028561:Transition Elements / Q000737:chemistry*
chemical_list: D021881:DNA, Catalytic; D008024:Ligands; D008667:Metalloproteins; D010455:Peptides; D028561:Transition Elements