title: A case of zoster sine herpete of the trigeminal nerve.
abstract: Varicella-zoster virus reactivation causes zoster (shingles), a syndrome characterized by severe pain and a vesicular rash. The present report details a case of varicella-zoster virus reactivation of the maxillary and mandibular division of the right trigeminal nerve without evidence of vesicular rash (zoster sine herpete). It is difficult to identify owing to no typical clinical signs such as vesicular eruption. Zoster sine herpete of the trigeminal nerve, in particular, is rarely reported. In this case, the diagnosis was based on clinical findings and was supported by the demonstration of an immunoglobulin G antibody. Zoster sine herpete of the trigeminal nerve, in particular, should be considered in patients with severe facial pain over specific dermatomes, if they do not demonstrate appreciable findings of traumatic neuropathy, tumor or herpes zoster.
authors.affiliation: Department of Dental Anesthesiology, Tokyo Dental College, Mihama-ku, Chiba, Japan. mkasahar@tdc.ac.jp
authors.forename: Masataka
authors.initials: M
authors.lastname: Kasahara
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ichinohe
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Sano
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Fukuda
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Kaneko
mesh_terms: D000639:Amitriptyline / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D005157:Facial Pain / Q000209:etiology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008875:Middle Aged; D009407:Nerve Block; D020433:Trigeminal Nerve Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D014775:Virus Activation; D031368:Zoster Sine Herpete / Q000175:diagnosis*
chemical_list: D018712:Analgesics, Non-Narcotic; D007074:Immunoglobulin G; D000639:Amitriptyline