title: Copper-catalyzed enantioselective propargylic amination of nonaromatic propargylic esters with amines.
abstract: The enantioselective propargylic amination of propargylic pentafluorobenzoates bearing an alkyl group at the propargylic position with amines in the presence of catalytic amounts of a copper complex and an optically active diphosphine such as BINAP has been found to give the corresponding propargylic amines in good yields with high enantioselectivity.
authors.affiliation: Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Yoshida
authors.forename: Gaku
authors.initials: G
authors.lastname: Hattori
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nishibayashi