title: Comparison between surgical outcomes of colorectal cancer in younger and elderly patients.
abstract: OBJECTIVE
  To compare the outcome of surgical treatment of colorectal adenocarcinoma in elderly and younger patients.
  
  
  METHODS
  The outcomes of 122 patients with colorectal adenocarcinoma who underwent surgical treatment between January 2004 and June 2009 were analyzed. The clinicopathological and blood biochemistry data of the younger group (< 75 years) and the elderly group (≥ 75 years) were compared.
  
  
  RESULTS
  There were no significant differences between the two groups in operation time, intraoperative blood loss, hospital stay, time to resumption of oral intake, or morbidity. The elderly group had a significantly higher rate of hypertension and cardiovascular disease. The perioperative serum total protein and albumin levels were significantly lower in the elderly than in the younger group. The serum carcinoembryonic antigen level was lower in the elderly than in the younger group, and there was a significant decreasing trend after the operation in the elderly group.
  
  
  CONCLUSIONS
  The short-term outcomes of surgical treatment in elderly patients with colorectal adenocarcinoma were acceptable. Surgical treatment in elderly patients was considered a selectively effective approach.
authors.affiliation: Center for Digestive Diseases, Northern Fukushima Medical Center, Fukushima 960-0502, Japan. longxuejin@hotmail.com
authors.forename: Longxue
authors.initials: L
authors.lastname: Jin
authors.forename: Norio
authors.initials: N
authors.lastname: Inoue
authors.forename: Naoki
authors.initials: N
authors.lastname: Sato
authors.forename: Susumu
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kanno
authors.forename: Yuko
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tasaki
authors.forename: Kinya
authors.initials: K
authors.lastname: Sato
authors.forename: Shun
authors.initials: S
authors.lastname: Sato
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Kaneko
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000473:pathology / Q000601:surgery*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D002272:Carcinoembryonic Antigen / Q000097:blood; D003082:Colectomy / Q000009:adverse effects; D015179:Colorectal Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D004435:Eating; D005260:Female; D006801:Humans; D007564:Japan; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009752:Nutritional Status; D018579:Patient Selection; D020127:Recovery of Function; D018570:Risk Assessment; D012307:Risk Factors; D012709:Serum Albumin / Q000378:metabolism; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002272:Carcinoembryonic Antigen; D012709:Serum Albumin