title: Aortic root and valve thrombosis after implantation of a left ventricular assist device.
abstract: We describe the case of a 60-year-old female who presented with a non-ST elevation myocardial infarction 3 months following placement of a non-pulsatile left ventricular assist device (LVAD). Aortic root angiography not only revealed extensive aortic root thrombosis and left main thrombotic obstruction, but also vividly demonstrated the causative mechanism. To our knowledge, this rarely described mechanism of LVAD thrombosis has not been reported as clearly as this case illustrates.
authors.affiliation: Section of Cardiology, Department of Internal Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
authors.forename: Benjamin H
authors.initials: BH
authors.lastname: Freed
authors.forename: Valluvan
authors.initials: V
authors.lastname: Jeevanandam
authors.forename: Neeraj
authors.initials: N
authors.lastname: Jolly
mesh_terms: D000800:Angioplasty, Balloon; D001011:Aorta; D001021:Aortic Valve; D009202:Cardiomyopathies / Q000628:therapy*; D000077542:Eptifibatide; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D010455:Peptides / Q000627:therapeutic use; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D010455:Peptides; D014665:Vasodilator Agents; D000077542:Eptifibatide