title: Can tantalum cones provide fixation in complex revision knee arthroplasty?
abstract: BACKGROUND
  The best method for managing large bone defects during revision knee arthroplasty is unknown. Metaphyseal fixation using porous tantalum cones has been proposed for severe bone loss. Whether this approach achieves osseointegration with low complication rates is unclear.
  
  
  OBJECTIVE
  We therefore asked: (1) What is the risk of infection in revision knee arthroplasty with large bone defects reconstructed with porous tantalum cones? (2) What is the rate of osseointegration with these cones? (3) What is the rate of loosening and reoperation? (4) Is knee function restored?
  
  
  METHODS
  We retrospectively reviewed 27 patients who had 33 tantalum cones (nine femoral, 24 tibial) implanted during 27 revision knee arthroplasties. There were 14 women and 13 men with a mean age of 64.6 years. Preoperative diagnosis was reimplantation for infection in 13 knees, aseptic loosening in 10, and wear-osteolysis in four. Patients were evaluated clinically and radiographically using the score systems of the Knee Society and followed for a minimum of 2 years (mean, 3.3 years; range, 2-5.7 years).
  
  
  RESULTS
  One knee with two cones was removed for infection. All but one cone showed osseointegration. One knee was revised for femoral cone and component loosening. There was one reoperation for femoral shaft fracture and one for superficial dehiscence. The mean Knee Society pain score improved from 40 points preoperatively to 79 points postoperatively. The mean function score improved from 19 points to 47 points.
  
  
  CONCLUSIONS
  Our observations suggest metaphyseal fixation with tantalum cones can be achieved. Longer-term followup is required to determine whether the fixation is durable.
authors.affiliation: Durham VA Medical Center, Durham, NC, USA. paul.lachiewicz@gmail.com
authors.forename: Paul F
authors.initials: PF
authors.lastname: Lachiewicz
authors.forename: Michael P
authors.initials: MP
authors.lastname: Bolognesi
authors.forename: Robert A
authors.initials: RA
authors.lastname: Henderson
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Soileau
authors.forename: Thomas Parker
authors.initials: TP
authors.lastname: Vail
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000379:methods; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007593:Joint Instability / Q000517:prevention & control; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000187:drug effects*; D010147:Pain Measurement; D011300:Preoperative Care / Q000379:methods; D011475:Prosthesis Failure; D016059:Range of Motion, Articular / Q000502:physiology*; D020127:Recovery of Function; D012086:Reoperation / Q000379:methods*; D012189:Retrospective Studies; D013635:Tantalum / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D013635:Tantalum