title: Participants' experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial: qualitative interview study.
abstract: OBJECTIVE
  To explore participants' experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial.
  
  
  METHODS
  In-depth interviews were conducted with 41 trial participants who had had their insulin therapy intensified during this trial. Data were analysed using an inductive, thematic approach.
  
  
  RESULTS
  The vast majority of participants were receptive towards intensifying treatment. Whilst some were happy simply to follow health professionals' recommendations, others saw taking two types of insulin as a more effective way of controlling their diabetes. Post-intensification, participants sought to remember to take their additional injections by developing injection-related strategies and daily routines. The need to inject insulin whilst in public often arose more frequently following intensification and was a consistent source of anxiety. Those who were worried about injecting in public sought to avoid having to do so; for example, by injecting in toilets or by advancing or delaying the timing of their injections.
  
  
  CONCLUSIONS
  IT was not increasing the number of daily injections per se which was problematic for the participants who had agreed to have their insulin therapies intensified, but the increased likelihood of having to inject insulin in public. Addressing concerns about injecting in public places may help promote adherence to intensified insulin regimens.
authors.affiliation: Centre for Population Health Sciences, University of Edinburgh, Edinburgh Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: N
authors.initials: N
authors.lastname: Jenkins
authors.forename: N
authors.initials: N
authors.lastname: Hallowell
authors.forename: A J
authors.initials: AJ
authors.lastname: Farmer
authors.forename: R R
authors.initials: RR
authors.lastname: Holman
authors.forename: J
authors.initials: J
authors.lastname: Lawton
mesh_terms: D002986:Clinical Trials as Topic; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000523:psychology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin