title: Complete recovery of ischemic cardiomyopathy from thrombotic thrombocytopenic purpura.
abstract: A 50 year old male HIV patient on antiretroviral therapy was admitted for chest pain. Upon admission, the patient was found to have elevated cardiac enzymes, acute thrombocytopenia, hemolytic anemia, acute pancreatitis and acute renal failure. The patient was diagnosed with thrombotic thrombocytopenic purpura/haemolytic uremic syndrome and emergency plasma exchange therapy was initiated along with aspirin, beta-blockers, steroids, and antiretroviral therapy. Patient responded well and demonstrated complete resolution of ischemic cardiomyopathy with left ventricular ejection fraction improving from 35% to 55% by the time of discharge. Essentially, prompt diagnosis and treatment can reverse cardiac damage induced by thrombotic thrombocytopenic purpura.
authors.affiliation: Department of Internal Medicine, Oncology and Cardiology, Staten Island University Hospital, New York, USA. gaddamsainath@gmail.com
authors.forename: Sainath
authors.initials: S
authors.lastname: Gaddam
authors.forename: Lata
authors.initials: L
authors.lastname: Pablani
authors.forename: Vinod
authors.initials: V
authors.lastname: Chainani
authors.forename: Ravi Raj
authors.initials: RR
authors.lastname: Kavuda
authors.forename: Tarun
authors.initials: T
authors.lastname: Nagrani
authors.forename: Georges
authors.initials: G
authors.lastname: Abou Rjaili
authors.forename: Meekoo
authors.initials: M
authors.lastname: Dhar
authors.forename: James C
authors.initials: JC
authors.lastname: Lafferty