title: [Case of upper airway stenosis after accidental ingestion of neutral detergent containing cationic surfactant (HDQ Neutral)].
abstract: We had a case of upper airway stenosis after accidental ingestion of neutral detergent containing cationic surfactant (HDQ Neutral). An 85-year-old man was transported to our hospital by ambulance after ingesting 50 mL of HDQ Neutral. On arrival, he had an edematous buccopharyngeal membrane with bleeding. Laryngeal edema was observed by laryngoscopy, and severe upper airway stenosis occurred. He also had hypoxemia and was therefore intubated and put on mechanical ventilation. After admission, his respiratory condition was stable. On day 3, upper airway edema had improved and extubation was performed. He was cured without other complications. Surfactants generally have low toxicity but can cause damage to the mucous membrane of the respiratory tract and gastrointestinal tract. Therefore, immediate evaluation and treatment are needed for intoxication with them. They can also cause harm to circulation dynamics or the central nerve system, and careful follow-up is therefore needed.
authors.affiliation: Tsuyama Central Hospital Emergency Center and Critical Care Unit.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nagae
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Naito
authors.forename: Shuji
authors.initials: S
authors.lastname: Okahara
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hikasa
authors.forename: Daisuke
authors.initials: D
authors.lastname: Okada
authors.forename: Shingo
authors.initials: S
authors.lastname: Hagioka
authors.forename: Naoki
authors.initials: N
authors.lastname: Morimoto
mesh_terms: D000059:Accidents; D000369:Aged, 80 and over; D000402:Airway Obstruction / Q000139:chemically induced* / Q000628:therapy; D003902:Detergents / Q000506:poisoning*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D007819:Laryngeal Edema / Q000139:chemically induced* / Q000628:therapy; D007829:Laryngostenosis / Q000139:chemically induced* / Q000628:therapy; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D012121:Respiration, Artificial; D013501:Surface-Active Agents / Q000506:poisoning*; D016896:Treatment Outcome
chemical_list: D003902:Detergents; D013501:Surface-Active Agents; D006854:Hydrocortisone