title: Diagnostic accuracy of dual-source CT coronary angiography with prospective ECG-triggering on different heart rate patients.
abstract: OBJECTIVE
  To evaluate the diagnostic accuracy of dual-source CT (DSCT) prospective ECG-triggering coronary angiography in patients with different heart rate (HR).
  
  
  METHODS
  103 patients with suspected coronary artery disease underwent DSCT prospective ECG-triggered coronary angiography and invasive coronary angiography (ICA). The patients were grouped by HR during CT scans: low HR (≤60 bpm, n = 34); medium HR (60 < HR ≤ 70 bpm, n = 36) and high HR (>70 bpm, n = 33). The sensitivity and specificity of DSCT in detecting ≥50% stenosis were compared among subgroups where ICA was the gold standard. Image quality was scored using a 4-point scale.
  
  
  RESULTS
  A total of 1,580 (95.9%) coronary artery segments were evaluable. Sensitivity and specificity were 82.8% and 98.4%, 88.3% and 98.7%, and 80.3% and 98.6% for different subgroups (all p > 0.05). The overall area under the curve of the receiver-operating characteristic analysis was 0.94. The image quality scores were 3.1 ± 0.3, 3.1 ± 0.3 and 3.0 ± 0.4 for subgroups (p > 0.05). The overall average effective radiation dose was 3.60 ± 1.60 mSv.
  
  
  CONCLUSIONS
  DSCT coronary angiography with prospective ECG-triggering could be just as accurate in patients with medium to high HR compared to those with low HR.
authors.affiliation: Department of Radiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, #167 Bei-Li-Shi Street, Beijing 100037, China.
authors.forename: Ming-Li
authors.initials: ML
authors.lastname: Sun
authors.forename: Bin
authors.initials: B
authors.lastname: Lu
authors.forename: Run-Ze
authors.initials: RZ
authors.lastname: Wu
authors.forename: Laura
authors.initials: L
authors.lastname: Johnson
authors.forename: Lei
authors.initials: L
authors.lastname: Han
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Fang-Fang
authors.initials: FF
authors.lastname: Yu
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Hou
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Wang
authors.forename: Shiliang
authors.initials: S
authors.lastname: Jiang
authors.forename: Yue-Jin
authors.initials: YJ
authors.lastname: Yang
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Qiao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods*; D016009:Chi-Square Distribution; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide