title: The British HIV Association national audit on the management of subjects co-infected with HIV and hepatitis B/C.
abstract: The aim of this work was to survey current service provision and adherence to the British HIV Association (BHIVA) guidelines for the management of HIV and hepatitis B/C co-infected patients in the UK. Sites were invited to complete a survey of local care arrangements for co-infected patients. A case-note audit of all co-infected attendees during a six-month period in 2009 was performed. Data including demographics, clinical parameters, hepatitis disease status, antiretroviral and hepatitis B/C therapy were collected. Using BHIVA guidelines as audit standards, the proportion of sites and subjects meeting each standard was calculated. One-hundred and forty sites (75%) responded and data from 973 eligible co-infected patients were submitted. Approximately a third of sites reported not re-checking hepatitis serology or vaccination titres annually. Of all co-infected patients, 122 (13%) were neither vaccinated nor immune to hepatitis A and 26 (5%) of patients with hepatitis C were neither vaccinated nor naturally immune to hepatitis B. Of HBsAg-positive subjects, 25 (6%) were receiving lamivudine as the sole drug with antihepatitis B activity. In the UK, the management of HIV and hepatitis B/C co-infection remains highly variable. Optimizing the care of this high-risk patient group is a priority.
authors.affiliation: Imperial College, London, UK. l.garvey@imperial.ac.uk
authors.forename: L
authors.initials: L
authors.lastname: Garvey
authors.forename: H
authors.initials: H
authors.lastname: Curtis
authors.forename: G
authors.initials: G
authors.lastname: Brook
mesh_terms: D005260:Female; D019983:Guideline Adherence; D015658:HIV Infections / Q000453:epidemiology / Q000628:therapy* / Q000821:virology*; D019538:Health Care Surveys; D006509:Hepatitis B / Q000453:epidemiology / Q000628:therapy* / Q000821:virology*; D006526:Hepatitis C / Q000453:epidemiology / Q000628:therapy* / Q000821:virology*; D006801:Humans; D008297:Male; D008485:Medical Audit; D006113:United Kingdom / Q000453:epidemiology; D014765:Viral Vaccines / Q000008:administration & dosage
chemical_list: D014765:Viral Vaccines