title: Use of a new curvilinear distractor to repair mandibular defects in dogs.
abstract: We have investigated the feasibility of using a new curvilinear distractor to repair mandibular defects in 6 mature male dogs. A mandibular defect was created by an oblique osteotomy between the distal planes of the bilateral second premolars, and a transport disc 10mm wide was made. After a 7-day latency period, distraction was activated at 0.5mm/12h and consolidation lasted for 6 or 12 weeks. Three dogs were killed after 6 and 12 weeks' consolidation for gross, radiographic, and histological observations to be made. Curvilinear distraction osteogenesis was successful in 5/6 animals. At both time points smooth curved bone had been restored in the distracted areas, and radiographic and histological examination showed that the generated bone was similar to normal bone after 12 weeks' consolidation. These results suggest that the curvilinear distractor could complete curvilinear distraction osteogenesis in dogs' mandibles.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, 145 Changle West Road, Xi'an, Shaanxi 710032, PR China.
authors.forename: Hongtao
authors.initials: H
authors.lastname: Shang
authors.forename: Xiaozhen
authors.initials: X
authors.lastname: Lin
authors.forename: Jinghua
authors.initials: J
authors.lastname: Du
authors.forename: Lisheng
authors.initials: L
authors.lastname: He
authors.forename: Yanpu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D015519:Bone Density; D001861:Bone Regeneration / Q000502:physiology*; D004285:Dogs; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D019647:Oral Surgical Procedures / Q000379:methods*; D019857:Osteogenesis, Distraction / Q000379:methods*; D010027:Osteotomy; D014945:Wound Healing