title: Myometrial invasion by endometrial carcinoma: evaluation with 3.0T MR imaging.
abstract: OBJECTIVE
  The purpose of this study was to investigate the efficacy of 3.0T MR imaging in the assessment of depth of myometrial invasion by endometrial carcinoma.
  
  
  METHODS
  Fifty women with histopathologically confirmed endometrial carcinoma underwent preoperative MR imaging at 3.0T. MR imaging findings were compared with microscopic pathologic findings in all cases. On evaluation of MR images and histopathological findings, myometrial invasion was classified as absent (tumor confined to the endometrium), superficial (less than 50% of myometrial thickness), or deep (50% or more of myometrial thickness) by two radiologists.
  
  
  RESULTS
  The sensitivity, specificity, and accuracy of the MR imaging in distinguishing no myometrial invasion from myometrial invasion were 95/95, 60/70, and 88/90%, respectively, and no and superficial myometrial invasion from deep myometrial invasion were 88/94, 97/94, and 94/92%, respectively.
  
  
  CONCLUSIONS
  In evaluation of the depth of myometrial invasion by endometrial carcinoma, 3.0T MR imaging has a high diagnostic accuracy that is equivalent to that of previously reported 1.5T MR imaging.
authors.affiliation: Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, Japan. sachi.k@med.tottori-u.ac.jp
authors.forename: Sachi
authors.initials: S
authors.lastname: Kaneda
authors.forename: Shinya
authors.initials: S
authors.lastname: Fujii
authors.forename: Takeru
authors.initials: T
authors.lastname: Fukunaga
authors.forename: Suguru
authors.initials: S
authors.lastname: Kakite
authors.forename: Toshio
authors.initials: T
authors.lastname: Kaminou
authors.forename: Junzo
authors.initials: J
authors.lastname: Kigawa
authors.forename: Tasuku
authors.initials: T
authors.lastname: Harada
authors.forename: Toshihide
authors.initials: T
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D001706:Biopsy; D003287:Contrast Media; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008536:Meglumine; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009942:Organometallic Compounds; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D008536:Meglumine; C072417:gadoterate meglumine