title: Urokinase plasminogen activator receptor levels in Behcet's disease.
abstract: OBJECTIVE
  To determine urokinase plasminogen activator receptor (uPAR) concentrations in Behcet patients with and without ocular involvement; and to investigate the associations between uPAR levels and clinical manifestations of Behcet's disease.
  
  
  METHODS
  Sixty-four patients with Behcet's disease (31 patients with and 33 patients without ocular involvement) and 23 healthy control subjects were included in this study. A complete ophthalmologic examination was performed. Venous blood was collected from all patients and control subjects. Serum uPAR levels were determined by using human uPAR immunoassay (Quantikine) kits.
  
  
  RESULTS
  There was no statistically significant difference in serum uPAR levels between the patients and the control subjects (p>0.05). There were no statistically significant correlations between uPAR levels and age, gender, duration of the disease, clinical manifestations (genital ulcer, arthritis, skin lesions, ocular and vascular involvements) and activity of the disease.
  
  
  CONCLUSIONS
  This finding is important since this is the first study regarding uPAR levels in Behcet's disease.
authors.affiliation: Ankara University, School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Birengel
authors.forename: F Nilüfer
authors.initials: FN
authors.lastname: Yalçındağ
authors.forename: Ali
authors.initials: A
authors.lastname: Yalçındağ
authors.forename: Esra
authors.initials: E
authors.lastname: Sahli
authors.forename: Figen
authors.initials: F
authors.lastname: Batıoğlu
mesh_terms: D000328:Adult; D000368:Aged; D001528:Behcet Syndrome / Q000097:blood* / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007118:Immunoassay; D008297:Male; D008875:Middle Aged; D055293:Receptors, Urokinase Plasminogen Activator / Q000097:blood*; D055815:Young Adult
chemical_list: D055293:Receptors, Urokinase Plasminogen Activator