title: Recent advances in the pathogenesis of hypertension in children.
abstract: This commentary discusses current knowledge of the pathogenesis of pediatric hypertension, focusing on the fact that adult health and, to a large extent, adult diseases, are deeply rooted in both hereditary and environmental factors that originate in childhood. Understanding these factors and their pathogenesis not only allows us to appreciate the etiology of pediatric hypertension, but also helps us to target our treatment and better manage the risk factors in the very young that may result in less cardiovascular and kidney disease among adults.
authors.affiliation: Department of Pediatric Nephrology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. ghaleb.daouk@childrens.harvard.edu
authors.forename: Ghaleb H
authors.initials: GH
authors.lastname: Daouk
authors.forename: Julie R
authors.initials: JR
authors.lastname: Ingelfinger
mesh_terms: D002648:Child; D004700:Endocrine System Diseases / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology; D007049:Iatrogenic Disease; D009765:Obesity / Q000150:complications; D012084:Renin-Angiotensin System / Q000502:physiology; D014652:Vascular Diseases / Q000150:complications