title: Cytomegalovirus retinitis in a seronegative patient with systemic lupus erythematosus on immunosuppressive therapy.
abstract: OBJECTIVE
  The purpose of this study is to report a rare case of cytomegalovirus (CMV) retinitis in a seronegative patient with systemic lupus erythematosus (SLE) on immunosuppressive therapy.
  
  
  METHODS
  A seronegative patient with SLE who was on immunosuppressive therapy developed CMV retinitis. The immunosuppressive therapy was tapered, and the patient was given intravitreal ganciclovir and foscarnet in addition to systemic ganciclovir. The follow-up visits were documented.
  
  
  RESULTS
  The patient responded to the treatment and there was complete resolution.
  
  
  CONCLUSIONS
  CMV retinitis is a rapidly progressive condition and patients on immunosuppressive therapy should be referred to an ophthalmologist for periodic check-up for early diagnosis and treatment of this devastating ophthalmic condition. For clinically resistant CMV retinitis in seronegative patients with SLE, a combination therapy of intravitreal foscarnet with oral and intravenous ganciclovir is useful.
authors.affiliation: National Institute of Ophthalmology, 1187/30 off Ghole Road, Shivajinagar, Pune, 411005, Maharashtra, India, adityapune4@gmail.com.
authors.forename: Aditya
authors.initials: A
authors.lastname: Kelkar
authors.forename: Jai
authors.initials: J
authors.lastname: Kelkar
authors.forename: Shreekant
authors.initials: S
authors.lastname: Kelkar
authors.forename: Shilpa
authors.initials: S
authors.lastname: Bhirud
authors.forename: Jyotirmoy
authors.initials: J
authors.lastname: Biswas