title: [Clinical course of influenza A(H1N1)v in children treated in Warsaw in season 2009/2010].
abstract: In the autumn 2009 in Poland there was an outbreak of influenza A(H1N1)v, approximately 1/3 of confirmed cases in children younger than 14 years. The aim of the study was an epidemiologic and clinical characteristics of pediatric patients with influenza A(H1N1)v and evaluation of antiviral treatment safety. The medical records of 100 children with confirmed influenza A(H1N1)v were reviewed. 48% of children had risk factors for severe clinical course, including 23 younger than 2 years. The most common symptoms were fever (89%) and cough (68%). In 20% children pneumonia was diagnosed, other complications were uncommon. 4 patients required mechanical ventilation and 3 died, all with severe underlying conditions. In 62% of patients oseltamivir was used and it was well tolerated.
authors.affiliation: Klinika Chorób Zakaźnych Wieku Dzieciecego, Warszawski Uniwersytet Medyczny. ewa.talarek@wum.edu.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Talarek
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Dembiński
authors.forename: Andrzej
authors.initials: A
authors.lastname: Radzikowski
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Smalisz-Skrzypczyk
authors.forename: Teresa
authors.initials: T
authors.lastname: Jackowska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Marczyńska
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D021821:Communicable Diseases, Emerging / Q000453:epidemiology*; D015897:Comorbidity; D003371:Cough / Q000453:epidemiology; D005260:Female; D005334:Fever / Q000453:epidemiology; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D008297:Male; D053139:Oseltamivir / Q000008:administration & dosage; D011014:Pneumonia / Q000453:epidemiology; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D012621:Seasons; D016896:Treatment Outcome; D014505:Urban Population / Q000706:statistics & numerical data*
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir