title: Efficient synthesis of 17-acetyl-13-(p-bromophenyl)-3-methoxy-11,11-bis(methoxycarbonyl)gona-1,3,5(10)-trienes.
abstract: We described an efficient synthesis of (8β,9β,14β)-17β-acetyl-13β-p-bromophenyl-11,11-di(methoxycarbonyl)-3-methoxygona-1,3,5(10)-triene, (8β,9α,14β)-17β-acetyl-13β-p-bromophenyl-11,11-di(methoxycarbonyl)-3-methoxygona-1,3,5(10)-triene, (8β,9β,14β)-13 β-p-bromophenyl-11,11-di(methoxycarbonyl)-17β-(2-hydroxyethyl)-3-methoxygona-1,3,5(10)-triene, and (8β,9β,14β)-13β-p-bromophenyl-11,11-di(methoxycarbonyl)-17β-(2-oxoxyethyl)-3-methoxygona-1,3,5(10)-triene in five or six steps from 1-iodo-4-methoxybenzocyclobutene and readily available materials.
authors.affiliation: Laboratoire Chimie Provence, UMR CNRS 6264, Faculté des Sciences et Techniques de Saint-Jérôme, Avenue Escadrille Normandie-Niémen, 13397 Marseille Cedex 20, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Galy
authors.forename: Maurice
authors.initials: M
authors.lastname: Santelli
mesh_terms: D000475:Alkenes / Q000737:chemistry; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000475:Alkenes; D013256:Steroids; C558934:butylene