title: An unusual case of meningitis.
abstract: We report on a patient who presented at our hospital with fever, headache, neck pain, partial nuchal rigidity and decreased vision of the left eye. The clinical history, biochemical and instrumental exams performed suggested meningitis but the final hypothesis achieved was an unusual case of Neuro-Behcet-Disease (NBD) without orogenital ulcerations at presentation and with normal MRI findings, whose course was complicated by fatal cerebral venous sinus thrombosis and intracranial haemorrhage. The post-mortem results confirmed the diagnosis. This is a rare case confirmed by anatomo-pathological findings where NBD can present itself as an acute meningeal syndrome that mimics central nervous system infections, making diagnosis difficult and delaying treatment.
authors.affiliation: Department of Neuroscience, Anaesthesia and Intensive Care IV, Ospedali Riuniti di Bergamo, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Gritti
authors.forename: Luigi A
authors.initials: LA
authors.lastname: Lanterna
authors.forename: Daniela
authors.initials: D
authors.lastname: Chinaglia
authors.forename: Ornella
authors.initials: O
authors.lastname: Manara
authors.forename: Laura
authors.initials: L
authors.lastname: Soavi
authors.forename: Anna
authors.initials: A
authors.lastname: Zilio
authors.forename: Fredy
authors.initials: F
authors.lastname: Suter
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D001921:Brain / Q000098:blood supply / Q000473:pathology; D001929:Brain Edema / Q000209:etiology; D002543:Cerebral Hemorrhage / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D015235:HLA-B Antigens / Q000032:analysis; D059949:HLA-B51 Antigen; D006801:Humans; D008279:Magnetic Resonance Imaging; D008582:Meningitis, Aseptic / Q000209:etiology*; D016920:Meningitis, Bacterial / Q000175:diagnosis; D009928:Organ Specificity; D012851:Sinus Thrombosis, Intracranial / Q000209:etiology; D019851:Thrombophilia / Q000209:etiology; D014657:Vasculitis / Q000209:etiology
chemical_list: D015235:HLA-B Antigens; D059949:HLA-B51 Antigen