title: [Interhemisphere asymmetry of hippocampus and neocortex in correlates of active and passive behavioural strategy in negative emotional situations].
abstract: The interhemisphere interaction of neurons in bilateral derivations from parietal and sensomotor areas of neocortex and the area CA1 of hippocampus were studied in rabbits with active and passive behavioural strategy in the open field by plotting histograms of crosscorrelation. In passive animals, there was asymmetry in bilateral neuronal interaction: with right-sided dominance in the neocortex and with left-sided that--in the hippocampus. On the contrary, in active rabbits, the left-sided dominance was observed in the neocortex, and the lateralization was not revealed in the hippocampus. The brain laterality was reflected in motor asymmetry of animals in preferring left or right turns in the open field. Passive rabbits made relatively more left turns, and the active animals--right turns. Systemic administration of agonist GABA(B) receptors phenibut decreased behavioural responses to emotional stimuli and eliminated interhemisphere asymmetry observed usually in negative emotional situations. Thus the interhemisphere asymmetry of the neocortex and hippocampus is correlated with individual typological characteristics of animals and reflects the readiness to preferential forms of behavioural responses in active and passive rabbits.
authors.forename: I V
authors.initials: IV
authors.lastname: Pavlova
authors.forename: M P
authors.initials: MP
authors.lastname: Rysakova
authors.forename: E A
authors.initials: EA
authors.lastname: Ziablintseva
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D058786:GABA-B Receptor Agonists / Q000494:pharmacology; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D019579:Neocortex / Q000502:physiology*; D011817:Rabbits; D018080:Receptors, GABA-B / Q000378:metabolism; D013315:Stress, Psychological
chemical_list: D058786:GABA-B Receptor Agonists; D018080:Receptors, GABA-B