title: Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin.
abstract: A highly stereoselective synthesis of a model C(18)-C(35) spiroketal unit (7) of integramycin has been accomplished via an enantioselective stannyl-crotylboration reaction and an N-iodosuccinimide-mediated spiroketalization of 19a.
authors.affiliation: Department of Chemistry, Scripps Florida, Jupiter, Florida 33458, United States.
authors.forename: Huikai
authors.initials: H
authors.lastname: Sun
authors.forename: Jason R
authors.initials: JR
authors.lastname: Abbott
authors.forename: William R
authors.initials: WR
authors.lastname: Roush
mesh_terms: D005663:Furans / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D005663:Furans; D009281:Naphthalenes; D013141:Spiro Compounds; C489772:integramycin; C520774:spiroketal