title: Suitability of porous silicon microparticles for the long-term delivery of redox-active therapeutics.
abstract: Thermal oxidation of porous Si microparticles provides an inert carrier for the long-term release of the anthracycline drug daunorubicin. Without prior oxidation, porous Si undergoes an undesirable side reaction with this redox active drug.
authors.affiliation: Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
authors.forename: Elizabeth C
authors.initials: EC
authors.lastname: Wu
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Andrew
authors.forename: Alex
authors.initials: A
authors.lastname: Buyanin
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Kinsella
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Sailor
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000633:toxicity; D002460:Cell Line; D003630:Daunorubicin / Q000008:administration & dosage / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry*; D006801:Humans; D008856:Microscopy, Fluorescence; D049329:Nanostructures / Q000737:chemistry; D010084:Oxidation-Reduction; D016062:Porosity; D012825:Silicon / Q000737:chemistry*
chemical_list: D000903:Antibiotics, Antineoplastic; D004337:Drug Carriers; D012825:Silicon; D003630:Daunorubicin