title: [Induced thymus aging: radiation model and application perspective for low intensive laser radiation].
abstract: The influence of gamma-radiation on morphofunctional state of thymus is rather like as natural thymus aging. However gamma-radiation model of thymus aging widely used to investigate geroprotectors has many shortcomings and limitations. Gamma-radiation can induce irreversible changes in thymus very often. These changes are more intensive in comparison with changes, which can be observed at natural thymus aging. Low intensive laser radiation can not destroy structure of thymus and its effects are rather like as natural thymus aging in comparison with gamma-radiation effects. There are many parameters of low intensive laser radiation, which can be changed to improve morphofunctional thymus characteristics in aging model. Using low intensive laser radiation in thymus aging model can be very perspective for investigations of aging immune system.
authors.forename: N N
authors.initials: NN
authors.lastname: Sevost'ianova
authors.forename: A V
authors.initials: AV
authors.lastname: Trofimov
authors.forename: N S
authors.initials: NS
authors.lastname: Lin'kova
authors.forename: V O
authors.initials: VO
authors.lastname: Poliakova
authors.forename: I M
authors.initials: IM
authors.lastname: Kvetnoĭ
mesh_terms: D000375:Aging / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D005720:Gamma Rays / Q000009:adverse effects; D006801:Humans; D007834:Lasers; D028022:Low-Level Light Therapy / Q000295:instrumentation*; D023421:Models, Animal; D051381:Rats; D013950:Thymus Gland / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects