title: Fullerenes for applications in biology and medicine.
abstract: Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology and medicine. Since a major focus in the latter has been on drug development and formulation, in this paper we highlight some representative studies related to such a focus, including the use of fullerenes for drug-like functions and for their improving the formulation of established drugs. Also discussed are some other potential medically relevant applications of fullerenes, such as their serving as potent agents in photodynamic therapy and magnetic imaging.
authors.affiliation: Department of Chemistry and Laboratory for Emerging Materials and Technology, Clemson University, Clemson, South Carolina 29634-0973, USA. pluo@clemson.edu
authors.forename: P
authors.initials: P
authors.lastname: Anilkumar
authors.forename: F
authors.initials: F
authors.lastname: Lu
authors.forename: L
authors.initials: L
authors.lastname: Cao
authors.forename: P G
authors.initials: PG
authors.lastname: Luo
authors.forename: J-H
authors.initials: JH
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Sahu
authors.forename: K N
authors.initials: KN
authors.lastname: Tackett
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: Y-P
authors.initials: YP
authors.lastname: Sun
mesh_terms: D000818:Animals; D019380:Anti-HIV Agents / Q000737:chemistry / Q000627:therapeutic use; D003287:Contrast Media; D004337:Drug Carriers / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000627:therapeutic use; D037741:Fullerenes / Q000737:chemistry / Q000627:therapeutic use*; D006678:HIV / Q000187:drug effects; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008545:Melanoma / Q000188:drug therapy; D008958:Models, Molecular; D050997:Nanomedicine / Q000379:methods*; D049329:Nanostructures / Q000627:therapeutic use; D010778:Photochemotherapy / Q000379:methods; D017319:Photosensitizing Agents / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D003287:Contrast Media; D004337:Drug Carriers; D016166:Free Radical Scavengers; D037741:Fullerenes; D017319:Photosensitizing Agents