title: Spinal epidermoid cyst in a SJL mouse: case report and literature review.
abstract: This report is the first description of a spinal epidermoid cyst (EC) in a SJL mouse and gives an overview on the occurrence of ECs in animals including dogs, horses, mice and rats. The EC was not detected grossly and the mouse did not display clinical signs or an altered rotarod performance. Microscopically, there was an oval cyst lined by stratified squamous epithelium that was attached to the dorsolateral meninges and caused moderate compression of the adjacent lumbar spinal cord. ECs in mice and rats are mainly located in the caudal part of the spinal cord with a variable, strain-dependent occurrence. ECs in mice and rats are not associated with clinical signs and can be interpreted as incidental findings.
authors.affiliation: Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Hansmann
authors.forename: V
authors.initials: V
authors.lastname: Herder
authors.forename: H
authors.initials: H
authors.lastname: Ernst
authors.forename: W
authors.initials: W
authors.lastname: Baumgärtner
mesh_terms: D000818:Animals; D002493:Central Nervous System Diseases / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D004285:Dogs; D004814:Epidermal Cyst / Q000737:chemistry / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D005260:Female; D033162:Incidental Findings; D007633:Keratins / Q000032:analysis; D008159:Lumbar Vertebrae; D008578:Meninges / Q000473:pathology*; D051379:Mice; D008815:Mice, Inbred Strains; D009043:Motor Activity; D051381:Rats; D012376:Rodent Diseases / Q000473:pathology*; D013045:Species Specificity; D013117:Spinal Cord Compression / Q000209:etiology / Q000662:veterinary*
chemical_list: D007633:Keratins