title: N-cyanomethylnorboldine: a new aporphine isolated from Alseodaphne perakensis (Lauraceae).
abstract: A phytochemical study of the bark of Alseodaphne perakensis has yielded three aporphine alkaloids: the new compound N-cyanomethylnorboldine (1), and the two known alkaloids N-methyllaurotetanine (2) and norboldine (3). The isolation was achieved by chromatographic techniques and the structural elucidation was performed via spectral methods, notably 1D- and 2D-NMR, UV, IR, and HRFABMS. The vasorelaxation activity of compound 1 has been studied.
authors.affiliation: Chemistry Department, Faculty of Science and Mathematic, University of Pendidikan Sultan Idris, Tg. Malim, Perak, Malaysia. azlan@upsi.edu.my
authors.forename: Mohd Azlan
authors.initials: MA
authors.lastname: Nafiah
authors.forename: Mat Ropi
authors.initials: MR
authors.lastname: Mukhtar
authors.forename: Hanita
authors.initials: H
authors.lastname: Omar
authors.forename: Kartini
authors.initials: K
authors.lastname: Ahmad
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
authors.forename: Marc
authors.initials: M
authors.lastname: Litaudon
authors.forename: Khalijah
authors.initials: K
authors.lastname: Awang
authors.forename: A Hamid A
authors.initials: AH
authors.lastname: Hadi
mesh_terms: D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019770:Lauraceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D001060:Aporphines