title: [Features of clinic, diagnostics and treatment of typhoid fever in young patients].
abstract: Typhoid fever is a dangerous infection. The article analyzes the clinical aspects, diagnostic possibilities and casual treatment of the young men in organized group with typhoid. It's shown that despite early hospitalization (at average of 5.5 days) the main manifestations peculiar to the "classical" infection retained. The majority (61.5%) had disease of moderate severity, mild form were at 37,4% of patients. Complications occurred in 5.0% of the patients: pneumonia (2.8%), myocarditis (2.2%) and pancreatits (2.2%). Pathogen isolated from patients with typhoid fever had reduced susceptibility to fluoroquinolones. Antimicrobial therapy showed the advantage of the 3 generation cephalosporin (ceftriaxone) compared with ciprofloxacin or a combination of the latter with cefotaxime.
authors.forename: A N
authors.initials: AN
authors.lastname: Kovalenko
authors.forename: K V
authors.initials: KV
authors.lastname: Zhdanov
authors.forename: V M
authors.initials: VM
authors.lastname: Volzhanin
authors.forename: M K
authors.initials: MK
authors.lastname: Shishkin
authors.forename: V S
authors.initials: VS
authors.lastname: Tokmakov
authors.forename: A V
authors.initials: AV
authors.lastname: Karpov
authors.forename: A A
authors.initials: AA
authors.lastname: Murachev
authors.forename: V A
authors.initials: VA
authors.lastname: Kondratenok
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002511:Cephalosporins / Q000008:administration & dosage*; D002939:Ciprofloxacin / Q000008:administration & dosage*; D006760:Hospitalization; D006801:Humans; D008297:Male; D014435:Typhoid Fever / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D002939:Ciprofloxacin