title: MRI in patients with inflammatory bowel disease.
abstract: Inflammatory bowel disease (IBD) affects ≈1.4 million people in North America and, because of its typical early age of onset and episodic disease course, IBD patients often undergo numerous imaging studies over the course of their lifetimes. Computed tomography (CT) has become the standard imaging modality for assessment of IBD patients because of its widespread availability, rapid image acquisition, and ability to evaluate intraluminal and extraluminal disease. However, repetitive CT imaging has been associated with a significant ionizing radiation risk to patients, making MRI an appealing alternative IBD imaging modality. Pelvic MRI is currently the imaging gold standard for detecting perianal disease, while recent studies indicate that MRI bowel-directed techniques (enteroclysis, enterography, colonography) can accurately evaluate bowel inflammation in IBD. With recent technical innovations leading to faster and higher resolution body MRI, the role of MRI in IBD evaluation is likely to continue to expand. Future applications include surveillance imaging, detection of mural fibrosis, and early assessment of therapy response.
authors.affiliation: Division of Abdominal Imaging and Interventional Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Gee
authors.forename: Mukesh G
authors.initials: MG
authors.lastname: Harisinghani
mesh_terms: D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media / Q000494:pharmacology; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology; D003952:Diagnostic Imaging / Q000379:methods*; D005402:Fistula / Q000473:pathology; D041981:Gastrointestinal Tract / Q000473:pathology; D006801:Humans; D007249:Inflammation; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D007422:Intestines / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media