title: Asymmetric synthesis of enantiopure isoxazolidinone monomers for the synthesis of β-oligopeptides by chemoselective amide ligation.
abstract: The design and general synthesis of enantiopure isoxazolidinone monomers as precursors for the preparation of enantiopure N-terminal hydroxylamine-β(3)-oligopeptides, which may be used as reaction partners with α-ketoacids in the decarboxylative amide ligation reaction, is described.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6354, USA.
authors.forename: M Elisa
authors.initials: ME
authors.lastname: Juarez-Garcia
authors.forename: Shouyun
authors.initials: S
authors.lastname: Yu
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Bode