title: The epigenetics of Alzheimer's disease--additional considerations.
abstract: The critical commentaries following our review of the epigenetics of Alzheimer's disease (AD) amplify a number of key points with respect to the role of 1-carbon metabolism, the phenomenon of allele-specific methylation, the potentially critical explanatory link provided by epigenetic mechanisms for genome-wide association and large-scale gene expression array studies, and new therapeutic approaches afforded by epigenetic manipulation in Alzheimer's disease.
authors.affiliation: Banner Sun Health Research Institute, Sun City, AZ, USA. joseph.rogers@bannerhealth.com
authors.forename: Joseph
authors.initials: J
authors.lastname: Rogers
authors.forename: Diego
authors.initials: D
authors.lastname: Mastroeni
authors.forename: Andrew
authors.initials: A
authors.lastname: Grover
authors.forename: Elaine
authors.initials: E
authors.lastname: Delvaux
authors.forename: Charisse
authors.initials: C
authors.lastname: Whiteside
authors.forename: Paul D
authors.initials: PD
authors.lastname: Coleman
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics* / Q000378:metabolism*; D000818:Animals; D019175:DNA Methylation / Q000235:genetics*; D044127:Epigenesis, Genetic / Q000235:genetics* / Q000502:physiology*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D008967:Molecular Biology / Q000639:trends*; D019875:One-Carbon Group Transferases / Q000235:genetics*; D057170:Translational Research, Biomedical / Q000639:trends*
chemical_list: D019875:One-Carbon Group Transferases