title: Bioinformatics approaches in the discovery and understanding of reproduction-related biomarkers.
abstract: The emerging field of bioinformatics in proteomics is introducing new algorithms in order to handle large and heterogeneous datasets and improve the knowledge-discovery process. Management systems, software construction and application, database population and leverage, as well as computed prediction, have crafted bioinformatics into a valuable tool for basic research. Human reproduction is one of many fields proteomics has been extensively studying over the last decade, accumulating complex experimental data at a rate far exceeding the ability to assimilate them. Transformation of the rapidly proliferating quantities of experimental information into a usable form in order to facilitate their analysis is a challenging task. On this track, bioinformatics, an essential part of proteomics research, aspires to amend inquiries into a better manipulated, a better handled and a better understood form so as to enhance existing knowledge expansion.
authors.affiliation: Proteomics Research Unit, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou, 115 27 Athens, Greece.
authors.forename: Athanasios K
authors.initials: AK
authors.lastname: Anagnostopoulos
authors.forename: Georgia
authors.initials: G
authors.lastname: Tsiliki
authors.forename: George
authors.initials: G
authors.lastname: Spyrou
authors.forename: George Th
authors.initials: GT
authors.lastname: Tsangaris
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D019295:Computational Biology / Q000379:methods*; D006801:Humans; D012098:Reproduction / Q000502:physiology*
chemical_list: D015415:Biomarkers