title: Microtubule end binding: EBs sense the guanine nucleotide state.
abstract: EB proteins accumulate at the tips of growing microtubules and recruit to them a multitude of factors to regulate microtubule functions. A new study suggests that EBs recognize microtubule ends by distinguishing between different states of the tubulin-bound guanine nucleotide.
authors.affiliation: Cell Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
authors.forename: Anna
authors.initials: A
authors.lastname: Akhmanova
authors.forename: Michel O
authors.initials: MO
authors.lastname: Steinmetz
mesh_terms: D000818:Animals; D006160:Guanosine Triphosphate / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D018716:Molecular Mimicry; D011485:Protein Binding; D014404:Tubulin / Q000378:metabolism*; D014981:Xenopus / Q000378:metabolism*
chemical_list: D008869:Microtubule-Associated Proteins; D014404:Tubulin; D006160:Guanosine Triphosphate