title: Overview of the winter wave of 2009 pandemic influenza A(H1N1)v in Vojvodina, Serbia.
abstract: OBJECTIVE
  To analyze the epidemiological data for pandemic influenza A(H1N1)v in the Autonomous Province of Vojvodina, Serbia, during the season of 2009/2010 and to assess whether including severe acute respiratory illness (SARI) hospitalization data to the surveillance system gives a more complete picture of the impact of influenza during the pandemic.
  
  
  METHODS
  From September 2009 to September 2010, the Institute of Public Health of Vojvodina conducted sentinel surveillance of influenza-like illnesses and acute respiratory infections in all hospitalized patients with SARI and virological surveillance of population of Vojvodina according to the European Centers for Disease Control technical document.
  
  
  RESULTS
  The pandemic influenza outbreak in the province started in October 2009 (week 44) in students who had returned from a school-organized trip to Prague, Bratislava, and Vienna. The highest incidence rate was 1090 per 100000 inhabitants, found in the week 50. The most affected age group were children 5-14 years old. A total of 1591 patients with severe illness were admitted to regional hospitals, with a case fatality rate of 2%, representing a hospitalization rate of 78.3 per 100000 inhabitants and a mortality rate of 1.6 per 100000. Most frequently hospitalized were 15-19 years old patients, male patients, and patients with pneumonia (P<0.001). The highest case fatality rate was found among patients with acute respiratory distress syndrome (P<0.001). Nasal/throat swabs were obtained for polymerase chain reaction test from 315 hospitalized patients and 20 non-hospitalized patients, and 145 (46%) and 15 (75%) specimens, respectively, tested positive on A(H1N1)v.
  
  
  CONCLUSIONS
  Sentinel influenza-like illness and SARI surveillance, both followed with virological surveillance, seem to be the optimal method to monitor the full scope of the influenza pandemic (from mild to severe influenza) in Vojvodina.
authors.affiliation: Provincial Secretariat for Health, Autonomous Province of Vojvodina, Boulevard Mihajla Pupina 16, Novi Sad, Serbia. vladimir.petrovic@vojvodina.gov.rs
authors.forename: Vladimir
authors.initials: V
authors.lastname: Petrović
authors.forename: Zorica
authors.initials: Z
authors.lastname: Seguljev
authors.forename: Gorana
authors.initials: G
authors.lastname: Cosić
authors.forename: Mioljub
authors.initials: M
authors.lastname: Ristić
authors.forename: Jasminka
authors.initials: J
authors.lastname: Nedeljković
authors.forename: Natasa
authors.initials: N
authors.lastname: Dragnić
authors.forename: Snezana
authors.initials: S
authors.lastname: Ukropina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology; D008297:Male; D008875:Middle Aged; D018571:Sentinel Surveillance; D055771:Serbia / Q000453:epidemiology; D055815:Young Adult