title: [Olive oil consumption and incidence of diabetes mellitus, in the Spanish sun cohort].
abstract: BACKGROUND
  The beneficial effects of the overall Mediterranean dietary pattern on cardiovascular risk factors and on carbohydrate metabolism are well known; however, it is unclear whether the consumption of olive oil in particular is able to reduce the incidence of type 2 diabetes.
  
  
  OBJECTIVE
  To evaluate the specific effect of olive oil consumption on the risk of developing type 2 diabetes mellitus in a large Spanish cohort (the SUN Project).
  
  
  METHODS
  We followed up 10,491 participants for a median of 5.7 years. Habitual diet was assessed at baseline with a semi-quantitative 136-item food-frequency questionnaire previously validated in Spain. The outcome of interest was incident type 2 diabetes diagnosed by a physician and confirmed by review of a medical report. The multivariate-adjusted odds ratios for incident type 2 diabetes for each of the 4 upper quintiles of olive oil consumption using the lowest quintile as the reference were assessed using logistic regression models.
  
  
  RESULTS
  At baseline mean age was 38.9 + 11.38 year with a BMI of 23.8 + 3.41 kg/m². Forty two new cases of diabetes mellitus were diagnosed during follow-up. The adjusted odds ratio for the highest vs. the lowest quintile of consumption of olive oil was 1.11 (95% CI: 0.45-2.78; p for trend = 0.32).
  
  
  CONCLUSIONS
  We found no association between olive oil consumption and the incidence of type 2 diabetes. The lack of association could be attributed to the small number of observed incident cases of diabetes. Further studies in Mediterranean countries with a longer follow-up and a higher baseline risk are needed to evaluate this association.
authors.affiliation: Sección de Nutrición Clínica y Dietética, Hospital de Navarra, Pamplona, España. amarisanchis@g.mail.com
authors.forename: A
authors.initials: A
authors.lastname: Marí-Sanchis
authors.forename: J J
authors.initials: JJ
authors.lastname: Beunza
authors.forename: M
authors.initials: M
authors.lastname: Bes-Rastrollo
authors.forename: E
authors.initials: E
authors.lastname: Toledo
authors.forename: F J
authors.initials: FJ
authors.lastname: Basterra Gortariz
authors.forename: M
authors.initials: M
authors.lastname: Serrano-Martínez
authors.forename: M A
authors.initials: MA
authors.lastname: Martínez-González
mesh_terms: D000368:Aged; D015992:Body Mass Index; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D038441:Diet, Mediterranean / Q000706:statistics & numerical data*; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D000069463:Olive Oil; D010938:Plant Oils; D018570:Risk Assessment; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D000069463:Olive Oil; D010938:Plant Oils