title: Limbal stem cell disease: management with scleral lenses.
abstract: BACKGROUND
  Limbal stem cell deficiency (LSCD) results from damage to or destruction of corneal stem cells.
  
  
  METHODS
  A retrospective review of clinical records of a patient with LSCD describes the use of scleral lenses in disease management.
  
  
  RESULTS
  A patient presented with a one-year history of clinically diagnosed LSCD, which was worsening despite aggressive topical and systemic medical therapy. The condition resolved rapidly with initiation of scleral lens wear. The integrity of the ocular surface was maintained for 18 months even after the cessation of lens wear.
  
  
  CONCLUSIONS
  Scleral lenses might allow some patients with LSCD to delay or avoid more aggressive surgical intervention.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA. Schornack.muriel@mayo.edu
authors.forename: Muriel M
authors.initials: MM
authors.lastname: Schornack
mesh_terms: D000328:Adult; D003261:Contact Lenses; D003316:Corneal Diseases / Q000473:pathology / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology*; D008297:Male; D012590:Sclera; D013234:Stem Cells / Q000473:pathology*; D014792:Visual Acuity