title: [Successful withdrawal from disseminated intravascular coagulation caused by disseminated carcinomatosis of bone marrow originated from gastric cancer treated by sequential therapy consisting of MTX and 5-FU and palliative radiotherapy].
abstract: A 5 8-year-old man with severe back pain caused by multiple vertebral metastases developed disseminated intravascular coagulation(DIC). We adopted palliative radiotherapy(8 Gy/1 day)for palliation of his back pain as initial treatment. Afterwards, we started sequential chemotherapy consisting of methotrexate(MTX)and 5-fluorouracil(5-FU). After two courses, DIC was resolved, and the patient was discharged in fair condition after five more courses of MTX and 5-FU therapy.
authors.affiliation: Dept. of Surgery, Ina Central Hospital, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Kubo
authors.forename: Nobumichi
authors.initials: N
authors.lastname: Takeuchi
authors.forename: Ataru
authors.initials: A
authors.lastname: Nakayama
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ogiwara
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsujimoto
authors.forename: Norio
authors.initials: N
authors.lastname: Ito
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Koiwai
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000556:secondary / Q000628:therapy*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000628:therapy*; D017809:Fatal Outcome; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D010166:Palliative Care; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*
chemical_list: D005472:Fluorouracil; D008727:Methotrexate