title: Biomechanics and tissue engineering.
abstract: Development of artificial scaffold for musculo-skeletal applications, especially in load-bearing situations, requires the consideration of biomechanical aspects for its integrity and its function. However, the biomechanical loading could also be used to favour tissue formation through mechano-transduction phenomena. Design of scaffold could take advantages of this intrinsic mechanical loading.
authors.affiliation: Laboratory of Biomechanical Orthopedics, Institute of Bioengineering, EPFL, Lausanne, Switzerland. dominique.pioletti@epfl.ch
authors.forename: D P
authors.initials: DP
authors.lastname: Pioletti
mesh_terms: D016723:Bone Remodeling / Q000502:physiology*; D018786:Bone Substitutes; D006801:Humans; D040542:Mechanotransduction, Cellular / Q000502:physiology; D013314:Stress, Mechanical; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D018786:Bone Substitutes