title: Hospital-based management of acute ischemic stroke following intravenous thrombolysis.
abstract: Timely administration of proven therapies remains the primary goal in acute stroke care. Following reperfusion therapy with intravenous thrombolysis, medical and neurological complications may develop in the hospitalized patient with acute ischemic stroke. Medical complications may include deep venous thrombosis, pulmonary embolism, aspiration, systemic infections and neuropsychiatric disturbances. Neurologic complications may include symptomatic intracranial hemorrhage, cerebral edema with elevated intracranial pressure, and post-stroke seizures. Early initiation of preventative strategies and proper management of common complications may improve both short-term and long-term outcomes. Here we review evidence-based management strategies for hospitalized acute ischemic stroke patients following intravenous thrombolysis.
authors.affiliation: Cerebrovascular Division, Department of Neurology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
authors.forename: Raid G
authors.initials: RG
authors.lastname: Ossi
authors.forename: James F
authors.initials: JF
authors.lastname: Meschia
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Barrett
mesh_terms: D055317:Evidence-Based Practice; D006760:Hospitalization; D006801:Humans; D007262:Infusions, Intravenous; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy