title: [Resistance to B-lactamines of bacteria responsible for endodontic root canal infections].
abstract: Samples were taken under strictly anaerobic conditions from the root canals of 22 patients having a tooth in which necrotic pulp was associated with an inflammatory peri-apical lesion an optical periodontitis. In the majority of cases (85%), these lesions were chronic and the pulp chamber was closed. One hundred and two strains were isolated, 71.7% of the bacteria being obligate anaerobes and 49.8% being Gram-negative bacilli. Their ability to produce beta-lactamases was tested and 8.8% gave a positive reaction in a cefinase test. These cefinase positive strains were nevertheless susceptible to 3rd-generation cephalosporins (cefoxitin) and to amoxicillin-clavulanate, with the exception of M. Morganii.
authors.affiliation: Equipe biologie buccale Fac. Med. dentaire Casablanca.
authors.forename: T
authors.initials: T
authors.lastname: Rochd
authors.forename: P
authors.initials: P
authors.lastname: Calas
authors.forename: M
authors.initials: M
authors.lastname: Jabri
authors.forename: C
authors.initials: C
authors.lastname: Roques
mesh_terms: D000190:Actinomyces / Q000145:classification / Q000187:drug effects; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001431:Bacteriological Techniques; D001439:Bacteroides / Q000145:classification / Q000187:drug effects; D002440:Cefoxitin / Q000627:therapeutic use; D002511:Cephalosporins; D003786:Dental Pulp Cavity / Q000382:microbiology; D003790:Dental Pulp Necrosis / Q000382:microbiology*; D006090:Gram-Negative Bacteria / Q000145:classification* / Q000187:drug effects / Q000201:enzymology; D006094:Gram-Positive Bacteria / Q000145:classification* / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D007202:Indicators and Reagents; D010462:Peptostreptococcus / Q000145:classification / Q000187:drug effects; D010485:Periapical Periodontitis / Q000382:microbiology; D018720:Prevotella / Q000145:classification / Q000187:drug effects; D013291:Streptococcus / Q000145:classification / Q000187:drug effects; D018440:beta-Lactam Resistance / Q000502:physiology*; D001618:beta-Lactamases / Q000032:analysis
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D007202:Indicators and Reagents; D002440:Cefoxitin; D019980:Amoxicillin-Potassium Clavulanate Combination; D001618:beta-Lactamases; C021720:nitrocefin