title: Virgatolides A-C, benzannulated spiroketals from the plant endophytic fungus Pestalotiopsis virgatula.
abstract: Virgatolides A-C (1-3), unique metabolites with a 3',4',5',6'-tetrahydrospiro[chroman-2,2'-pyran] core, were isolated from cultures of the plant endophytic fungus Pestalotiopsis virgatula. Compounds 1-3 possess two previously undescribed skeletons originating from a benzannulated 6,6-spiroketal and one (2 and 3) and two (1) γ-lactone units, respectively. The structure of 1 was secured by X-ray crystallography.
authors.affiliation: Key Laboratory of Systematic Mycology & Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Yikang
authors.initials: Y
authors.lastname: Si
authors.forename: Xuejun
authors.initials: X
authors.lastname: Jiang
authors.forename: Liangdong
authors.initials: L
authors.lastname: Guo
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Che
mesh_terms: D018360:Crystallography, X-Ray; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification*; D013098:Xylariales / Q000737:chemistry*
chemical_list: D005663:Furans; D013141:Spiro Compounds; C520774:spiroketal; C559531:virgatolide A; C559533:virgatolide B; C559532:virgatolide C