title: [A case of gastric cancer with lung, Virchow and para-aortic lymph node metastases treated successfully using PTX/5'-DFUR].
abstract: A 6 3-year-old male presented with dysphagia. Gastrointestinal endoscopic examination showed advanced gastric cancer type 3, which was diagnosed as well-differentiated adenocarcinoma. Computed tomography(CT)showed bilateral lung tumors, hugely enlarged Virchow and para-aortic lymph nodes. He was treated with combination chemotherapy of weekly paclitaxel(PTX)and doxifluridine(5'-DFUR). PTX was administered at a dose of 80mg/m2 on day 1, 8 and 15, and 5'- DFUR was orally administered at a dose of 533mg/m / 2day for 5 days followed by withdrawal for 2 days. After four courses of treatment, CT showed an almost complete disappearance of the lung and lymph node metastases. After 13 courses of treatment, total gastrectomy and lymph node dissection were performed. One year postoperatively, the patient died of a recur- rence.
authors.affiliation: Dept. of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Toya
authors.forename: Izumi
authors.initials: I
authors.lastname: Takeyoshi
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Arakawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sunose
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yoshinari
authors.forename: Osamu
authors.initials: O
authors.lastname: Totsuka
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Keitaro
authors.initials: K
authors.lastname: Hirai
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001011:Aorta / Q000473:pathology*; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005467:Floxuridine / Q000008:administration & dosage / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D005467:Floxuridine; D017239:Paclitaxel; C025034:doxifluridine