title: [Influence of peptides from pineal gland on thymus function at aging].
abstract: The interference between thymus and pineal gland during their involution is considered in this review. The research data about influence of thymus peptides on pineal gland and pineal peptides on thymus is summarized. Analysis of these data showed that pineal peptides (epithalamin, epitalon) had more effective geroprotective effect on thymus involution in comparison with geroprotective effect of thymic peptides (thymalin, thymogen) on involution of pineal gland. The key mechanisms of pineal peptides effect on thymus dystrophy is immunoendocrine cooperation, which is realized as transcription's activation of various proteins.
authors.forename: N S
authors.initials: NS
authors.lastname: Lin'kova
authors.forename: V O
authors.initials: VO
authors.lastname: Poliakova
authors.forename: A V
authors.initials: AV
authors.lastname: Trofimov
authors.forename: N N
authors.initials: NN
authors.lastname: Sevost'ianova
authors.forename: I M
authors.initials: IM
authors.lastname: Kvetnoĭ
mesh_terms: D000276:Adjuvants, Immunologic / Q000378:metabolism; D000375:Aging / Q000276:immunology / Q000378:metabolism*; D000818:Animals; D013507:Endocrine Surgical Procedures / Q000009:adverse effects; D020249:Hormone Replacement Therapy; D006801:Humans; D008550:Melatonin / Q000378:metabolism / Q000627:therapeutic use; D023421:Models, Animal; D036361:Peptide Hormones / Q000378:metabolism* / Q000627:therapeutic use; D010870:Pineal Gland / Q000378:metabolism* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy; D013949:Thymus Extracts / Q000627:therapeutic use; D013950:Thymus Gland / Q000378:metabolism* / Q000601:surgery
chemical_list: D000276:Adjuvants, Immunologic; D036361:Peptide Hormones; D013949:Thymus Extracts; D008550:Melatonin