title: Morbidity and mortality of surgery for endometrial cancer in the oldest old.
abstract: OBJECTIVE
  Although endometrial cancer commonly occurs in elderly women, little is known about the perioperative outcomes of the oldest women (> 80 years of age) who are treated surgically.
  
  
  METHODS
  We performed an analysis of women ≥ 65 years of age with endometrial cancer who underwent hysterectomy from 1998-2007 and who were registered in the Nationwide Inpatient Sample.
  
  
  RESULTS
  A total of 25,698 women were identified. Compared with women who were 65-69 years old, women who were ≥ 85 years old were more likely to have perioperative surgical complications (12% vs 17%), postoperative medical complications (24% vs 34%), and a longer length of stay (3 vs 5 days) and to require a transfusion (6% vs 10%; P < .05 for all). The perioperative mortality rate was 0.4% in women who were 65-69 years old compared with 1.6% in women who were ≥ 85 years old (P < .0001).
  
  
  CONCLUSIONS
  The morbidity that is associated with surgery for endometrial cancer is significantly higher in women who are > 80 years old, even after medical comorbidities have been considered.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. jw2459@columbia.edu
authors.forename: Jason D
authors.initials: JD
authors.lastname: Wright
authors.forename: Sharyn N
authors.initials: SN
authors.lastname: Lewin
authors.forename: Nicanor I
authors.initials: NI
authors.lastname: Barrena Medel
authors.forename: Xuming
authors.initials: X
authors.lastname: Sun
authors.forename: William M
authors.initials: WM
authors.lastname: Burke
authors.forename: Israel
authors.initials: I
authors.lastname: Deutsch
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Herzog
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion / Q000706:statistics & numerical data; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000706:statistics & numerical data; D007431:Intraoperative Complications / Q000453:epidemiology* / Q000401:mortality; D007902:Length of Stay / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D016896:Treatment Outcome