title: Drug prescriptions of adults with adolescent depression in a community sample.
abstract: OBJECTIVE
  The prescription drugs have, to our knowledge, not been much studied in epidemiological samples with long-term follow-up. Accordingly, our purpose was to analyze the use of prescription drugs in adults with adolescent depression.
  
  
  METHODS
  A population-based cohort of adolescents (n = 2465) was screened for the presence of depressive symptoms and diagnosed according to a structured interview. Totally, 362 individuals were identified as depressed and compared with 250 non-depressed controls. The prescription drugs were evaluated at the age of 29-31 years from a register kept by the National Health and Welfare Board.
  
  
  RESULTS
  The formerly depressed females received significantly more prescription drugs, such as antidepressants, antiepileptics, antibacterials, antimycotics, and antihistamines for systemic use as well as other drugs, compared with controls (15.6 ± 27.4 vs 8.2 ± 7.4 recipes, p < 0.001). Formerly depressed males did not differ from controls regarding prescription drugs.
  
  
  CONCLUSIONS
  The females but not males with adolescent depression subsequently received more prescription drugs than non-depressed peers. Depressed female adolescents received more psychotropic and non-psychotropic drugs later in life compared to the non-depressed. This might be as a result of physical illnesses, different treatment-seeking behaviors, or somatizing reactions.
authors.affiliation: Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden. aivar@telia.com
authors.forename: Aivar
authors.initials: A
authors.lastname: Päären
authors.forename: Lars
authors.initials: L
authors.lastname: von Knorring
authors.forename: Ulf
authors.initials: U
authors.lastname: Jonsson
authors.forename: Hannes
authors.initials: H
authors.lastname: Bohman
authors.forename: Gunilla
authors.initials: G
authors.lastname: Olsson
authors.forename: Anne-Liis
authors.initials: AL
authors.lastname: von Knorring
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000928:Antidepressive Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D015331:Cohort Studies; D003866:Depressive Disorder / Q000188:drug therapy* / Q000453:epidemiology; D015340:Epidemiologic Research Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055553:Prescription Drugs / Q000627:therapeutic use*; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012042:Registries; D012737:Sex Factors; D013548:Sweden / Q000453:epidemiology
chemical_list: D000928:Antidepressive Agents; D055553:Prescription Drugs; D011619:Psychotropic Drugs