title: Secure closure of the tracheal incision after natural orifice transluminal endoscopic surgery with a surgical sealant (CoSeal).
abstract: BACKGROUND
  To evaluate the effectiveness of surgical sealant (CoSeal) in sealing the tracheal assess sites after transtracheal thoracoscopy.
  
  
  METHODS
  Two dogs underwent transtracheal thoracic exploration and pericardial window creation. The thoracic cavity was approached with flexible bronchoscope through a 9-mm tracheal incision. The pericardial window was performed with a needle knife via the working channel of the bronchoscope, and the tracheal assess site was closed with CoSeal using a rubber catheter. The integrity of tracheal healing was evaluated under positive pressure ventilation.
  
  
  RESULTS
  Transtracheal creation of pericardial window and closure of tracheal incision with CoSeal was successfully performed in both dogs. There was no evidence of air leaks from the chest tube during positive pressure ventilation. Autopsy revealed no injury to the mediastinum and intrathoracic structure.
  
  
  CONCLUSIONS
  Endoscopic closure of tracheal access site of NOTES with CoSeal appears to be a feasible technique.
authors.affiliation: Chang Gung University, Taoyuan, Taiwan, ROC.
authors.forename: Yun-Hen
authors.initials: YH
authors.lastname: Liu
authors.forename: Yi-Cheng
authors.initials: YC
authors.lastname: Wu
authors.forename: Tzu-Ping
authors.initials: TP
authors.lastname: Chen
authors.forename: Po-Jen
authors.initials: PJ
authors.lastname: Ko
mesh_terms: D000818:Animals; D001999:Bronchoscopy; D004285:Dogs; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D011092:Polyethylene Glycols; D013906:Thoracoscopy / Q000379:methods*; D014132:Trachea / Q000601:surgery*
chemical_list: C513322:CoSeal; D011092:Polyethylene Glycols