title: Effects of progressive resistance strength training on knee biomechanics during single leg step-up in persons with mild knee osteoarthritis.
abstract: BACKGROUND
  The goal of this study was to determine if increasing strength in primary knee extensors and flexors would directly affect net knee joint moments during a common functional task in persons with knee osteoarthritis.
  
  
  METHODS
  An exploratory single sample clinical trial with pre-post treatment measures was used to study volunteers with clinical diagnosis of mild knee osteoarthritis (OA) in one knee. Subjects participated in an individually supervised training program 3 times a week for eight weeks consisting of progressive resistive exercises for knee extensors and knee flexors. Pre and post training outcome assessments included: 1. Net internal knee joint moments, 2. Electromyography of primary knee extensors and flexors, and 3. Self-report measures of knee pain and function. The distribution of lower extremity joint moments as a percent of the total support moment was also investigated.
  
  
  RESULTS
  Pain, symptoms, activities of daily life, quality of life, stiffness, and function scores showed significant improvement following strength training. Knee internal valgus and hip internal rotation moments showed increasing but non-statistically significant changes post-training. There were no significant differences in muscle co-contraction activation of the Quadriceps and Hamstrings.
  
  
  CONCLUSIONS
  While exercise continues to be an important element of OA management, the results of this study suggest improvements in function, pain, and other symptoms, as a result of strength training may not be causally related to specific biomechanical changes in net joint moments.
authors.affiliation: Department of Rehabilitation Medicine, Physical Therapy Program, University of Washington, Seattle, WA, USA. kmcquade@u.washington.edu
authors.forename: Kevin James
authors.initials: KJ
authors.lastname: McQuade
authors.forename: Anamaria Siriani
authors.initials: AS
authors.lastname: de Oliveira
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000503:physiopathology*; D020370:Osteoarthritis, Knee / Q000503:physiopathology* / Q000534:rehabilitation*; D016059:Range of Motion, Articular; D055070:Resistance Training / Q000379:methods*; D019415:Torque; D016896:Treatment Outcome