title: Comparison of technetium-99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy: a preliminary study.
abstract: This first clinical prospective study was conducted to use of technetium-99m immunoglobulin G ((99m)Tc-IgG) as compared with autologous (99m)Tc-red blood cells (RBC) in gated blood pool ventriculography. We studied 12 patients who referred to us for a possible diagnosis of liver hemangioma or infection. Six patients underwent gated planar blood pool (GPBP) acquisition using (99m)Tc-RBC and 6 GPBP acquisition using (99m)Tc-IgG. The use of (99m)Tc-IgG in cardiac blood pool studies provided comparable images to (99m)Tc-RBC. In conclusion, (99m)Tc-IgG, which is readily available and needs only a single injection, may be an attractive alternative to (99m)Tc-RBC for the estimation of various cardiac function parameters like left ventricular function.
authors.affiliation: Golestan Research Centre of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Javadi
authors.forename: Isa Neshandar
authors.initials: IN
authors.lastname: Asli
authors.forename: Shahriar
authors.initials: S
authors.lastname: Semnani
authors.forename: Sara
authors.initials: S
authors.lastname: Jallalat
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Ansari
authors.forename: Abdullatif
authors.initials: A
authors.lastname: Amini
authors.forename: Maryam
authors.initials: M
authors.lastname: Barekat
authors.forename: Majid
authors.initials: M
authors.lastname: Assadi
mesh_terms: D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006321:Heart / Q000000981:diagnostic imaging*; D006391:Hemangioma / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D007074:Immunoglobulin G; D007553:Isotope Labeling; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds
chemical_list: D007074:Immunoglobulin G; D015609:Organotechnetium Compounds; C079358:technetium TC 99m polyclonal IgG