title: Surface-functionalized fluorescent silica nanoparticles for the detection of ATP.
abstract: The design of two-dyed fluorescent silica nanoparticles for ATP detection is presented. The indicator dye possesses a dipicolyl-amine (DPA) unit complexed with Zn(II) as a receptor function for ATP while a rhodamine derivative is used as the reference dye. The nanoparticles were fully characterized regarding analytical performance, morphology and cytocompatibility.
authors.affiliation: REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
authors.forename: Artur J
authors.initials: AJ
authors.lastname: Moro
authors.forename: Jennifer
authors.initials: J
authors.lastname: Schmidt
authors.forename: Tristan
authors.initials: T
authors.lastname: Doussineau
authors.forename: Alejandro
authors.initials: A
authors.lastname: Lapresta-Fernandéz
authors.forename: Joachim
authors.initials: J
authors.lastname: Wegener
authors.forename: Gerhard J
authors.initials: GJ
authors.lastname: Mohr
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis*; D000588:Amines / Q000737:chemistry; D000818:Animals; D002460:Cell Line; D056831:Coordination Complexes / Q000737:chemistry / Q000633:toxicity; D005456:Fluorescent Dyes / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D010848:Picolinic Acids / Q000737:chemistry; D051381:Rats; D012822:Silicon Dioxide / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013499:Surface Properties; D015032:Zinc / Q000737:chemistry
chemical_list: C501847:2,2'-dipicolylamine; D000588:Amines; D056831:Coordination Complexes; D005456:Fluorescent Dyes; D010848:Picolinic Acids; D012822:Silicon Dioxide; D000255:Adenosine Triphosphate; D015032:Zinc