title: [Novel markers in osteo-oncology: the tartrate resistant acid phosphatase in myeloma bone disease].
abstract: In tumors characterized by a high osteotropism, such as multiple myeloma, the measurement of bone metabolism markers is helpful in monitoring both severity and prognosis of the skeletal disease. Here, we review the pathophysiology of these markers including tartrate resistant acid phosphatase (TRAcP), which appears highly specific and closely related to the extent of myeloma bone lesions.
authors.affiliation: Dipartimento di Medicina Interna e Oncologia, Università, Bari.
authors.forename: Sabino
authors.initials: S
authors.lastname: Strippoli
authors.forename: Stefania
authors.initials: S
authors.lastname: Stucci
authors.forename: Franco
authors.initials: F
authors.lastname: Dammacco
authors.forename: Franco
authors.initials: F
authors.lastname: Silvestris
mesh_terms: D000135:Acid Phosphatase / Q000097:blood / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism*; D001859:Bone Neoplasms / Q000097:blood / Q000201:enzymology* / Q000503:physiopathology; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000378:metabolism*; D009101:Multiple Myeloma / Q000097:blood / Q000201:enzymology* / Q000503:physiopathology; D000071681:Tartrate-Resistant Acid Phosphatase
chemical_list: D014408:Biomarkers, Tumor; D007527:Isoenzymes; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase