title: Cutaneous manifestation of silicone dissemination from a PIP implant--a case for prophylactic explantation?
abstract: The recent withdrawal of PIP (Poly Implant Prosthese, France) implants for breast augmentation enforced by the Medicines and Healthcare products Regulatory Agency (MHRA) on 31st March 2010 has ignited speculation into possible side effects relating to an unauthorized gel fill content. Local and migratory silicone granulomata and regional lymphadenopathy are well reported in the literature. Gel bleed from high cohesive gel implants with similar effect is also well known. However dissemination to sites distant from the breast manifest as cutaneous abnormalities in a patient implanted with a PIP product raises concern. We report such a case.
authors.affiliation: McIndoe Surgical Centre, East Grinstead RH19 3EB, UK. nhcawrse@hotmail.com
authors.forename: N H
authors.initials: NH
authors.lastname: Cawrse
authors.forename: M A
authors.initials: MA
authors.lastname: Pickford
mesh_terms: D000328:Adult; D018427:Breast Implants / Q000009:adverse effects*; D020878:Device Removal; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology