title: Suprasellar tuberculoma presenting as panhypopituitarism.
abstract: Suprasellar tuberculomas are exceptionally rare. We present the case of a middle aged male who presented with generalised apathy and meningism of two weeks duration. Neuroimaging was suggestive of tuberculomas in suprasellar cistern, while endocrinological investigation showed panhypopituitarism manifesting as pituitary hypothyroidism, hypocortisolism, and hyperprolactinemia. Cerebrospinal fluid examination showed lymphocytic reaction with raised proteins. A diagnosis of suprasellar tuberculoma with panhypopituitarism was made. The patient was started on antituberculous treatment and hormone replacement which led to remarkable improvement in condition of patient and resolution of tuberculous granuloma in follow up imaging.
authors.affiliation: Dept of Medicine, LTM Medical College and General Hospital, Sion, Mumbai-400 022.
authors.forename: Uma Su
authors.initials: US
authors.lastname: Sundar
authors.forename: Vishal V
authors.initials: VV
authors.lastname: Ramteke
authors.forename: Meghna S
authors.initials: MS
authors.lastname: Vaidya
authors.forename: Dyaneshwar C
authors.initials: DC
authors.lastname: Asole
authors.forename: Nivedita D
authors.initials: ND
authors.lastname: Moulick
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D002555:Cerebrospinal Fluid; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D020249:Hormone Replacement Therapy; D006801:Humans; D006966:Hyperprolactinemia / Q000000981:diagnostic imaging; D007018:Hypopituitarism / Q000000981:diagnostic imaging / Q000209:etiology; D007037:Hypothyroidism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016862:Tuberculoma, Intracranial / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000995:Antitubercular Agents