title: [Estimation of uncertainty of measurement in clinical biochemistry].
abstract: The uncertainty of measurement (UM) or measurement uncertainty is known as the parameter associated with the result of a measurement. Repeated measurements usually reveal slightly different results for the same analyte, sometimes a little higher, sometimes a little lower, because the results of a measurement are depending not only by the analyte itself, but also, by a number of error factors that could give doubts about the estimate. The uncertainty of the measurement represent the quantitative, mathematically expression of this doubt. UM is a range of measured values which is probably to enclose the true value of the measured. Calculation of UM for all types of laboratories is regularized by the ISO Guide to the Expression of Uncertainty in Measurement (abbreviated GUM) and the SR ENV 13005 : 2003 (both recognized by European Accreditation). Even if the GUM rules about UM estimation are very strictly, the offering of the result together with UM will increase the confidence of customers (patients or physicians). In this study the authors are presenting the possibilities of UM assessing in labs from our country by using the data obtained in the procedures of methods validation, during the internal and external quality control.
authors.affiliation: Investigaţii Medicale PRAXIS Iaşi.
authors.forename: Maria
authors.initials: M
authors.lastname: Enea
authors.forename: Cristina
authors.initials: C
authors.lastname: Hristodorescu
authors.forename: Corina
authors.initials: C
authors.lastname: Schiriac
authors.forename: Dana
authors.initials: D
authors.lastname: Morariu
authors.forename: Tr
authors.initials: T
authors.lastname: Mutiu
authors.forename: Irina
authors.initials: I
authors.lastname: Dumitriu
authors.forename: B
authors.initials: B
authors.lastname: Gurzu
mesh_terms: D000068:Accreditation; D001671:Biochemistry; D002138:Calibration; D005062:European Union; D006801:Humans; D007755:Laboratories, Hospital / Q000592:standards; D008432:Mathematical Computing; D008956:Models, Chemical; D011786:Quality Control; D012015:Reference Standards; D012383:Romania; D035501:Uncertainty