title: A new, blue gene highlights glutamate and hippocampus in depression.
abstract: Depression is a common and debilitating psychiatric syndrome with a complex risk architecture marked by interacting genetic and environmental factors. In this issue of Neuron, the study by Kohli et al. (2011) reports a novel genome-wide supported risk variant for depression that affects hippocampal gene expression, anatomy, and biochemistry.
authors.affiliation: Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany.
authors.forename: Heike
authors.initials: H
authors.lastname: Tost
authors.forename: Andreas
authors.initials: A
authors.lastname: Meyer-Lindenberg