title: Rapid-onset dystonia-parkinsonism.
abstract: Rapid-onset dystonia-parkinsonism (RDP) is a rare condition with autosomal-dominant inheritance causing dystonia and parkinsonism which develop over a short period of time. It results from abnormalities in the Na(+)/K(+)-ATPase pump due to mutations in the ATP1A3 gene. This chapter reviews the clinical features, genetics, and diagnosis of this disorder.
authors.affiliation: Division of Movement Disorders, Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA. hgeyer@montefiore.org
authors.forename: Howard L
authors.initials: HL
authors.lastname: Geyer
authors.forename: Susan B
authors.initials: SB
authors.lastname: Bressman
mesh_terms: D003937:Diagnosis, Differential; D020821:Dystonic Disorders / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D006801:Humans