title: Carbamazepine induced DRESS syndrome.
abstract: We present here an 18-yr-old male who presented with intermittent fever of moderate grade and of 15 days duration, followed by maculopapular erythematous rashes over upper and lower extremities, face, and trunk developing over 10-12 days. He was suffering from recurrent seizures since last 3 months for which he was started on carbamazepine 200mg twice daily for the past 6 weeks. He was febrile on admission. Generalized lymphadenopathy with discreet, non-matted, firm and tender inguinal lymph nodes. Patch test with 1% and 5% solution of carbamazepine was strongly positive.
authors.affiliation: Department of Medicine, HAL Hospital, Bangalore 560 017, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Chauhan
authors.forename: Swati
authors.initials: S
authors.lastname: Anand
authors.forename: Sindha
authors.initials: S
authors.lastname: Thomas
authors.forename: H C A
authors.initials: HC
authors.lastname: Subramanya
authors.forename: Gyanranjan
authors.initials: G
authors.lastname: Pradhan
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D001706:Biopsy; D002220:Carbamazepine / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000150:complications; D003875:Drug Eruptions; D004342:Drug Hypersensitivity; D004802:Eosinophilia / Q000139:chemically induced* / Q000150:complications; D004827:Epilepsy / Q000188:drug therapy*; D005076:Exanthema / Q000139:chemically induced* / Q000150:complications; D006801:Humans; D006979:Hyperthermia, Induced; D008206:Lymphatic Diseases / Q000139:chemically induced* / Q000150:complications; D008297:Male; D010328:Patch Tests; D012882:Skin Tests; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine