title: Trends in cervical cancer in young women in Hubei, China.
abstract: OBJECTIVE
  This study was performed to determine whether the incidence of cervical cancer in women aged 35 or younger has changed for the past 30 years and to examine the clinical characteristics of the cases.
  
  
  METHODS
  The clinical and pathological data of 6257 patients with cervical cancer treated between January 1975 and December 2009 were retrospectively analyzed.
  
  
  RESULTS
  The prevalence of young (≤ 35 years old) patients steadily increased from 2.8% to 15.7% for the past 30 years. The ratio of adenocarcinoma also rose from 1975-1979 to 2005-2009. In an analysis by age group, in group A, adenocarcinoma was found in 17% (≤ 35 years old); in group B, 7.1% (> 35 years old) [χ² = 78.92, P < 0.0001]. The clinical presentation presented showed that 36.4% of patients presented mainly postcoital bleeding in group A, whereas the symptom of irregular genital bleeding predominated in group B (P < 0.0001). The patients detected by routine cytological screening in group A (8.7%) were more than the patients in group B (3%).
  
  
  CONCLUSIONS
  The prevalence of cervical cancer in young women has been increasing steadily in Hubei, China. It is necessary for all sexually active women and women aged 35 years or even younger to undergo cervical cancer screening.
authors.affiliation: Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan, People’s Republic of China. chb2105@sohu.com
authors.forename: Hong-Bing
authors.initials: HB
authors.lastname: Cai
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Huang
authors.forename: Xiao-Nan
authors.initials: XN
authors.lastname: Li
authors.forename: Dao-Mei
authors.initials: DM
authors.lastname: Lie
authors.forename: Quan
authors.initials: Q
authors.lastname: Zhou
authors.forename: Feng-Lian
authors.initials: FL
authors.lastname: Pan
authors.forename: Zu-Hui
authors.initials: ZH
authors.lastname: Wang
authors.forename: Zhi-Yin
authors.initials: ZY
authors.lastname: Li
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Wang
authors.forename: Yin
authors.initials: Y
authors.lastname: Dai
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D014626:Vaginal Smears; D055815:Young Adult