title: Isolated cholangiolitis revealed by 18F-FDG-PET/CT in a patient with fever of unknown origin.
abstract: Cholangiolitis, inflammation of the cholangioles, is difficult to diagnose by conventional imaging modalities. We report a case of cholangiolitis revealed by fluorine-18 fluoro desoxyglucose positron emission tomography-computerized tomography ((18)F-FDG-PET/CT) after about 9 months of recurrent fevers. A 20 years old girl with a history of recurrent fevers and repeated workups at different hospitals, which didn't diagnosed the source of fever, was admitted with a recent episode of fever. An (18)F-FDG-PET/CT was requested, which demonstrated focal hypermetabolic activity in the lateral segment of the left lobe of the liver. A liver biopsy showed inflammation of small biliary ducts consistent of cholangiolitis. Enterococcus casseliflavus was found on performed cultures. This represents the first case of cholangiolitis revealed by (18)F-FDG-PET/CT imaging.
authors.affiliation: Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. codrion@yahoo.com
authors.forename: Ion
authors.initials: I
authors.lastname: Codreanu
authors.forename: Hongming
authors.initials: H
authors.lastname: Zhuang
mesh_terms: D001648:Bile Canaliculi / Q000000981:diagnostic imaging*; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000000981:diagnostic imaging; D008107:Liver Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D019788:Fluorodeoxyglucose F18