title: Peri-ictal bed leaving in temporal lobe epilepsy: incidence and lateralizing value.
abstract: We analyzed peri-ictal bed leaving (PBL) symptoms in 105 patients with temporal lobe epilepsy (TLE). All patients were classified as Engel I at the 2-year follow-up visit. Histopathological examination revealed hippocampal sclerosis (TLE-HS) in 64 patients and other lesions in 38 patients (TLE-other); 3 patients had no lesions. We reviewed 412 seizures. PBL was defined as lateralized leaving of the bed occurring during the seizure or up to 3 minutes after the end of the seizure. PBL was observed in 28 of 105 patients (26.7%), and in 45 of 412 seizures (10.9%). PBL occurred more frequently in patients with TLE-HS than in patients with TLE-other (32.8% vs 17.1%, P=0.058). PBL was ipsilateral to the seizure onset in 71.4% of patients and 71.2% of seizures (P=0.012 and P<0.001). In patients with TLE-HS, PBL was ipsilateral to seizure onset in 76.2% of patients and 81.2% of seizures (P=0.008 and P<0.001). In patients with TLE-other, PBL was ipsilateral to seizure onset in 42.8% of patients and 46.1% of seizures. There were no differences in the incidence and lateralizing value between patients with right-sided and those with left-sided TLE. PBL is a relatively frequent peri-ictal sign in patients with TLE. The side of PBL in patients with TLE-HS lateralizes the seizure onset to the ipsilateral temporal lobe.
authors.affiliation: Behavioral and Social Neuroscience Reasearch Group, Central European Institute of Technology, Masaryk University, Brno, Czech Republic. klara.musilova@fnusa.cz
authors.forename: K
authors.initials: K
authors.lastname: Musilová
authors.forename: R
authors.initials: R
authors.lastname: Kuba
authors.forename: M
authors.initials: M
authors.lastname: Brázdil
authors.forename: I
authors.initials: I
authors.lastname: Tyrlíková
authors.forename: I
authors.initials: I
authors.lastname: Rektor
mesh_terms: D000293:Adolescent; D000328:Adult; D001332:Automatism / Q000453:epidemiology / Q000209:etiology*; D004833:Epilepsy, Temporal Lobe / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D014741:Video Recording; D055815:Young Adult