title: Clinical implications of the early detection of urinary microalbumin in diabetic patients using a new high performance liquid chromatography (HPLC) method.
abstract: We assessed urine albumin in 180 diabetics by conventional immunonephelometry (IN) and HPLC methods. Those with HPLC but not IN detectable albuminuria had higher BP, worse glycaemic control and more vascular events (p<0.05 for all) but received fewer vascular risk reduction treatments.
authors.affiliation: Department of Nephrology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia. Electronic address: sumuditha@hotmail.com.
authors.forename: Dhammika
authors.initials: D
authors.lastname: Gunasekara
authors.affiliation: Path West, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
authors.forename: Liz
authors.initials: L
authors.lastname: Byrnes
authors.affiliation: Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
authors.forename: Suzanne
authors.initials: S
authors.lastname: Brown
authors.affiliation: Path West, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Beilby
authors.affiliation: Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.
authors.forename: Joey
authors.initials: J
authors.lastname: Kaye
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000175:diagnosis*; D001786:Blood Glucose; D001794:Blood Pressure; D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000592:standards; D003920:Diabetes Mellitus / Q000652:urine*; D042241:Early Diagnosis; D006801:Humans; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000379:methods / Q000592:standards; D014652:Vascular Diseases
chemical_list: D001786:Blood Glucose