title: Effect of potassium ferrate(VI) on survival and reproduction of Ichthyophthirius multifiliis tomonts.
abstract: Ichthyophthirius multifiliis is an important freshwater teleost pathogen that can infect most species of freshwater fish worldwide and often leads to significant economic losses to the aquaculture industry. Potassium ferrate(VI), as a potential therapeutic agent for external protozoan parasite infections, has been proven to kill I. multifiliis theronts effectively; however, no information is available on effects of potassium ferrate(VI) exposure to I. multifiliis tomonts. This study evaluated the effects of potassium ferrate(VI) on the survival and reproduction of I. multifiliis tomonts. The results of experiment 1 showed that potassium ferrate(VI) at concentrations of 2.4, 4.8, 9.6, and 19.2 mg/L resulted in tomont survival rates of 82.2%, 34.2%, 14.6%, and 0, respectively, and significant differences were noted in tomont reproduction between the treatments and the control (P < 0.05). Additionally, this study was designed to determine the effect of potassium ferrate(VI) toxicity on age of the tomont. The results indicated that encysted I. multifiliis was more resistant to potassium ferrate(VI) treatments. In addition, this study was designed to investigate I. multifiliis tomont survival and reproduction when collected from infested goldfish in potassium ferrate(VI) solutions at different concentrations (0, 2.4, 4.8, 9.6, and 19.2 mg/L) for 30 min. It was found that the tomont survivals in the treatments were significantly lower than those in the control (P < 0.05). This study demonstrated that a bath with potassium ferrate(VI) possibly was an effective method to treat ichthyophthiriasis.
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, People's Republic of China. feiling@nwsuaf.edu.cn
authors.forename: Fei
authors.initials: F
authors.lastname: Ling
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Wang
authors.forename: Gao-Xue
authors.initials: GX
authors.lastname: Wang
authors.forename: Xiao-Ning
authors.initials: XN
authors.lastname: Gong
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D006054:Goldfish / Q000469:parasitology; D016803:Hymenostomatida / Q000187:drug effects* / Q000302:isolation & purification; D058085:Iron Compounds / Q000494:pharmacology*; D017680:Potassium Compounds / Q000494:pharmacology*
chemical_list: D000981:Antiprotozoal Agents; D058085:Iron Compounds; D017680:Potassium Compounds; C044384:potassium ferrate