title: [The seroprevalence rate, vaccination rate and seroconversion rate of hepatitis A in central region of Korea].
abstract: OBJECTIVE
  Acute hepatitis A (HAV) is markedly increasing recently on. Some patients with acute hepatitis A show severe clinical course. The seroprevalence rate of IgG anti-HAV has been changing with the regions and the times. Vaccination and seroconversion rate of HAV are not well known. In this study, we aimed to study the difference of seroprevalence rate of IgG anti-HAV according to various clinical factors and to know the vaccination rate and seroconversion rate below 10 years old in the central region of South Korea including Cheonan city.
  
  
  METHODS
  Seven hundred seventy two subjects were included in the study from January to September 2009. We analyzed seroprevalence rate of IgG anti-HAV according to sex, age, region, and other viral markers. We interviewed the history of vaccination(1st, 2nd) and analyzed seroconversion rate according to vaccination time below 10 years old.
  
  
  RESULTS
  The total seroprevalence rate of IgG anti-HAV was 65.3%. The seroprevalence rate of IgG anti-HAV rate in 2nd, 3rd, and 4th decade was very low (1.9%, 18.8%, 44.8%). The vaccination rate of children was about 50%. The seroconversion rate after 1st, and 2nd vaccination were 85%, 96%.
  
  
  CONCLUSIONS
  Catch-up vaccination for teenagers and young adults is needed. Immunizing children with HAV vaccine as a routine schedule should be considered.
authors.affiliation: Departments of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
authors.forename: Seung Wook
authors.initials: SW
authors.lastname: Yun
authors.forename: Won Kyung
authors.initials: WK
authors.lastname: Lee
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Cho
authors.forename: Sung Hoon
authors.initials: SH
authors.lastname: Moon
authors.forename: Hyun Deok
authors.initials: HD
authors.lastname: Shin
authors.forename: Se Young
authors.initials: SY
authors.lastname: Yun
authors.forename: Suk Bae
authors.initials: SB
authors.lastname: Kim
authors.forename: Jeong Eun
authors.initials: JE
authors.lastname: Shin
authors.forename: Hong Ja
authors.initials: HJ
authors.lastname: Kim
authors.forename: Il Han
authors.initials: IH
authors.lastname: Song
authors.forename: Kun Song
authors.initials: KS
authors.lastname: Lee
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology* / Q000517:prevention & control; D035922:Hepatitis A Antibodies / Q000097:blood*; D022362:Hepatitis A Vaccines; D017957:Hepatitis A Virus, Human / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea; D016036:Seroepidemiologic Studies
chemical_list: D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines; D007074:Immunoglobulin G