title: Modeling the relationship between drug lipophilicity and potential for an interaction with orlistat.
authors.affiliation: Hoffmann-La Roche, Inc, Nutley, NJ, USA.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Zhi
mesh_terms: D019440:Anti-Obesity Agents / Q000494:pharmacology*; D018592:Cross-Over Studies; D004347:Drug Interactions; D005260:Female; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007783:Lactones / Q000494:pharmacology*; D008297:Male; D008954:Models, Biological; D000077403:Orlistat; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism*
chemical_list: D019440:Anti-Obesity Agents; D007783:Lactones; D004364:Pharmaceutical Preparations; D000077403:Orlistat