title: The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics.
abstract: The evolutionarily conserved INO80 family of ATP-dependent chromatin-remodeling enzymes has roles in many nuclear processes, including transcription, DNA repair, and DNA replication. Here, we discuss the in vivo and in vitro properties of these enzymes, focusing on recent studies which suggest that members of this family govern the deposition and removal of the histone variant H2A.Z.
authors.affiliation: Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: C L
authors.initials: CL
authors.lastname: Peterson
mesh_terms: D000818:Animals; D042002:Chromatin Assembly and Disassembly; D004265:DNA Helicases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D020033:Protein Isoforms / Q000378:metabolism; D021122:Protein Subunits / Q000378:metabolism
chemical_list: D006657:Histones; D020033:Protein Isoforms; D021122:Protein Subunits; D004265:DNA Helicases