title: [Blood-stream catheter related infection in inpatient children receiving parenteral nutrition].
abstract: Blood-stream catheter related infection is the most severe complication in patients carrying a central venous catheter. Parenteral nutrition (PN) use seems to be a risk factor for developing a catheter-related infection (CRI).
  
  
  METHODS
  In order to know the incidence of CRI in children to further implement policies to reduce nosocomial infection, we review all charts of children (1 month to 17 years) who received parenteral nutrition while in hospital. All episodes of fever + positive blood culture were recorded. Infection rate was defined as number of episodes/1000 Parenteral nutrition days.
  
  
  RESULTS
  48 positive blood cultures was obtained from 120 patients. Infection rate was 37.8/1000 days. Incidence was significantly higher in infants and toddlers (52% vs 29.8%, p = 0.016). Most frequent organisms were coagulase negative Staph. (56.8%), Gram negative bacilli (20.8%), Staph aureus (12.5%) and fungus (12.5%). No difference in incidence were found according to the underlying disease or the length of PN use.
  
  
  CONCLUSIONS
  Infection rate in our PN inpatient patients was significantly higher. PN may represent a risk factor for developing a CRI. Specific measurements and policies need to be implemented to overcome present situation.
authors.affiliation: Unidad de Nutrición Clínica, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: E
authors.initials: E
authors.lastname: Vaquero Sosa
authors.forename: E
authors.initials: E
authors.lastname: Izquierdo García
authors.forename: M
authors.initials: M
authors.lastname: Arrizabalaga Asenjo
authors.forename: C
authors.initials: C
authors.lastname: Gómez Peñalba
authors.forename: J M
authors.initials: JM
authors.lastname: Moreno Villares
mesh_terms: D000293:Adolescent; D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D016469:Fungemia / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007297:Inpatients; D008297:Male; D010288:Parenteral Nutrition / Q000009:adverse effects*; D012307:Risk Factors