title: Bioadhesive properties of β-limit dextrin.
abstract: OBJECTIVE
  β-Limit dextrin has been studied for many years as a means to investigate the internal structures of amylose and amylopectin. However its role as an excipient in the pharmaceutical industry has never been reported. This paper is the first one in a series to explore its potential use as an excipient to aid drug delivery.
  
  
  METHODS
  The bioadhesive properties of β-limit dextrin were studied using a texture analyser and compared with two well-known bioadhesive polymers - carbopol and chitosan (as controls).
  
  
  RESULTS
  The β-limit dextrin has significant mucoadhesive properties; similar to carbopol but superior to chitosan.
  
  
  CONCLUSIONS
  The nature of β-limit dextrin (a starch derivative) makes it safe to consume and provides a natural alternative when compared with synthetic polymers. In addition, the polysaccharide can be digested by salivary amylase and thus provide a clean mouth feel.
authors.affiliation: Glycologic Limited, 70 Cowcaddens Road, Glasgow, UK. e.qi@glycologic.co.uk
authors.forename: Xin
authors.initials: X
authors.lastname: Qi
authors.forename: Richard F
authors.initials: RF
authors.lastname: Tester
mesh_terms: D000180:Acrylic Resins; D000268:Adhesiveness; D048271:Chitosan / Q000737:chemistry; D003912:Dextrins / Q000737:chemistry*; D016503:Drug Delivery Systems; D005079:Excipients / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry; D013607:Tablets
chemical_list: D000180:Acrylic Resins; D003912:Dextrins; D005079:Excipients; D011145:Polyvinyls; D013607:Tablets; C006912:carboxypolymethylene; D048271:Chitosan