title: Can odors of TCM be captured by electronic nose? The novel quality control method for musk by electronic nose coupled with chemometrics.
abstract: Musk is a precious and wide applied material in traditional Chinese medicine, also, an important material for the perfume industry all over the world. To establish a rapid, cost-effective and relatively objective assessment for the quality of musk, different musk samples, including authentic, fake and adulterate, were collected. A oxide sensor based electronic nose (E-nose) was employed to measure the musk samples, the E-nose generated data were analyzed by principal component analysis (PCA), the responses of 18 sensors of E-nose were evaluated by loading analysis. Results showed that a rapid evaluation of complex response of the samples could be obtained, in combination with PCA and the perception level of the E-nose was given better results in the recognition values of the musk aroma. The authentic, fake and adulterate musk could be distinguished by E-nose coupled with PCA, sensor 2, 3, 5, 12, 15 and 17 were found to be able to better discriminate between musk samples, confirming the potential application of an electronic instrument coupled with chemometrics for a rapid and on-line quality control for the traditional medicines.
authors.affiliation: China Military Institute of Chinese Meteria Medica, Intergrative Medicine Centre, 302 Military Hospital, Beijing 100039, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Ye
authors.forename: Cheng
authors.initials: C
authors.lastname: Jin
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Xingfeng
authors.initials: X
authors.lastname: Li
authors.forename: Haitao
authors.initials: H
authors.lastname: Wang
authors.forename: Pingye
authors.initials: P
authors.lastname: Deng
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Wu
authors.forename: Xiaohe
authors.initials: X
authors.lastname: Xiao
mesh_terms: D000818:Animals; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D003670:Deer; D004581:Electronics; D005229:Fatty Acids, Monounsaturated; D008516:Medicine, Chinese Traditional; D015233:Models, Statistical; D009812:Odorants / Q000032:analysis*; D025341:Principal Component Analysis; D011786:Quality Control; D012903:Smell; D014835:Volatilization
chemical_list: D005229:Fatty Acids, Monounsaturated; C008563:musk