title: Profile of HIV/AIDS patients in a tertiary hospital in Istanbul, Turkey.
abstract: BACKGROUND
  In Turkey, the first HIV/AIDS case was reported in 1985. Although HIV/AIDS incidence has been increasing, only 3,671 cases have been documented to date in this country, with a population of 71,517,100. The aim of this study was to determine the epidemiologic and clinical features of patients with HIV infection and AIDS followed during a 3.5-year period.
  
  
  METHODS
  A total of 136 HIV-infected patients attending Infectious Diseases and Clinical Microbiology Outpatient Clinic of Haseki Training and Research Hospital between January 2006 and June 2009 were included in the study. Epidemiologic and clinical data, such as age, gender, marital status, occupation, level of education, transmission routes, condom usage, type of screening tests, clinical findings, and CD4 T-cell counts and viral loads at diagnosis, were collected retrospectively from case records completed on admission.
  
  
  RESULTS
  Patients with a diagnosis of HIV infection comprised a group of 136 persons (80% men, mean age 36 years [range, 20-72 years]). Six patients (8%) were university graduates. Heterosexual intercourse was the most common route of transmission (60%), followed by homosexual intercourse and intravenous drug use. Almost all women (24 out of 25; 96%) acquired the infection from their husbands. Median CD4 T-cell count at diagnosis was 302/mm3 (range, 9-1,270). On admission, CD4 T-cell count was < 200/mm3 in 39%, 200-350/mm3 in 30%, and ≯350/mL in 31%. Mean viral load at diagnosis was 1,033,871 copies/mL. Forty-four percent of the patients were admitted with obvious clinical signs and symptoms, whereas 56% were diagnosed through screening tests.
  
  
  CONCLUSIONS
  Poorly educated individuals and men constituted the majority of the cases. Most women acquired the disease from their husbands. Considering the poor level of education among the patients we studied, effective educational programs should be developed to reduce the transmission of HIV. Although heterosexual intercourse was the most common route of transmission, 38% of the patients we studied reported male-to-male intercourse. This is markedly higher than the 9% rate of transmission by this route in Turkey.
authors.affiliation: Infectious Diseases and Clinical Microbiology, Haseki Training and Research Hospital, Istanbul, Turkey. drhayat1@hotmail.com
authors.forename: Hayat Kumbasar
authors.initials: HK
authors.lastname: Karaosmanoglu
authors.forename: Ozlem Altuntas
authors.initials: OA
authors.lastname: Aydin
authors.forename: Ozcan
authors.initials: O
authors.lastname: Nazlican
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology; D000328:Adult; D000368:Aged; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D008297:Male; D008875:Middle Aged; D012725:Sexual Behavior; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult