title: FEN nucleases: bind, bend, fray, cut.
abstract: In this issue, Orans et al. (2011) and Tsutakawa et al. (2011) report exciting insights into the molecular principles governing diverse endo- and exonucleolytic cleavage specificities of members of the RAD2/FEN superfamily of nucleases, which have critical roles in DNA replication and maintenance.
authors.affiliation: Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Research Triangle Park, NC 27709, USA. williamsrs@niehs.nih.gov
authors.forename: R Scott
authors.initials: RS
authors.lastname: Williams
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Kunkel