title: The discovery of MMP7 inhibitors exploiting a novel selectivity trigger.
authors.affiliation: Global Structural Chemistry, AstraZeneca Mölndal, Mölndal, Sweden. Karl.Edman@astrazeneca.com
authors.forename: Karl
authors.initials: K
authors.lastname: Edman
authors.forename: Mark
authors.initials: M
authors.lastname: Furber
authors.forename: Paul
authors.initials: P
authors.lastname: Hemsley
authors.forename: Cristian
authors.initials: C
authors.lastname: Johansson
authors.forename: Garry
authors.initials: G
authors.lastname: Pairaudeau
authors.forename: Jens
authors.initials: J
authors.lastname: Petersen
authors.forename: Michael
authors.initials: M
authors.lastname: Stocks
authors.forename: Anu
authors.initials: A
authors.lastname: Tervo
authors.forename: Alison
authors.initials: A
authors.lastname: Ward
authors.forename: Edward
authors.initials: E
authors.lastname: Wells
authors.forename: Lisa
authors.initials: L
authors.lastname: Wissler
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D020134:Catalytic Domain; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D004353:Drug Evaluation, Preclinical; D057166:High-Throughput Screening Assays; D020783:Matrix Metalloproteinase 7 / Q000378:metabolism; D061965:Matrix Metalloproteinase Inhibitors; D008969:Molecular Sequence Data; D011480:Protease Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016415:Sequence Alignment
chemical_list: D061965:Matrix Metalloproteinase Inhibitors; D011480:Protease Inhibitors; D020783:Matrix Metalloproteinase 7