title: Basic science and clinical aspects of mesh infection in pelvic floor reconstructive surgery.
abstract: OBJECTIVE
  Bacterial colonization following mesh-augmented pelvic floor reconstructive surgery for pelvic organ prolapse is probably an underestimated consideration.
  
  
  METHODS
  Although clinical infections are rare, subclinical contamination of the polypropylene mesh has been systematically demonstrated by bacteriological analyses during mesh implantation and on explanted meshes.
  
  
  RESULTS
  A model of subclinical mesh infection does exist and bacterial colonization and mesh shrinkage have recently been correlated experimentally.
  
  
  CONCLUSIONS
  New meshes with surface modifications or an antibiotic or antiseptic coating should be explored.
authors.affiliation: Obstetrics and Gynaecology Department, Caremeau University Hospital, Nîmes, France. renaud.detayrac@chu-nimes.fr
authors.forename: Renaud
authors.initials: R
authors.lastname: de Tayrac
authors.forename: Vincent
authors.initials: V
authors.lastname: Letouzey
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D017773:Pelvic Floor / Q000601:surgery*; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011126:Polypropylenes / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D011183:Postoperative Complications / Q000209:etiology*; D012307:Risk Factors; D013526:Surgical Mesh / Q000009:adverse effects / Q000382:microbiology*
chemical_list: D011126:Polypropylenes