title: The Need for New Anti-Hepatitis C Virus Therapeutic Strategies: Targeting the cellular micro-ribonucleic acids?
abstract: Infection with the hepatitis C virus (HCV) is a worldwide problem. Patients with chronic HCV infection who are non-responders to standard therapy represent a growing population within the HCV epidemic. Novel, more efficient and tolerable therapies are urgently needed. This review discusses the recent results showing that targeting miR-122, a micro-ribonucleic acid (MicroRNA) that enhances HCV replication, is a new anti-HCV therapy with a high barrier to resistance.
authors.affiliation: Department of Microbiology & Immunology, Faculty of Medicine, Montreal University; Montreal, Quebec, Canada; and Montreal University Hospital Research Center (CR-CHUM), St-Luc Hospital, Montreal, Quebec, Canada. Email: elias_a_said@yahoo.fr.
authors.forename: Elias A
authors.initials: EA
authors.lastname: Said