title: Fatal Balamuthia mandrillaris infection in a gorilla - first case of balamuthiasis in Germany.
abstract: BACKGROUND
  A 12-year-old female western lowland gorilla died in a zoological garden in Germany after exhibiting general neurological signs.
  
  
  METHODS
  Balamuthia mandrillaris was identified as causative agent by indirect immunofluorescent staining of brain sections and confirmed by PCR and respective sequencing.
  
  
  RESULTS
  The animal suffered from a chronic progressive necrotizing amebic meningoencephalitis.
  
  
  CONCLUSIONS
  This is the first case of Balamuthia amebic encephalitis in Germany.
authors.affiliation: German Primate Center, Göttingen, Germany. kmaetz@gwdg.de
authors.forename: Kerstin
authors.initials: K
authors.lastname: Mätz-Rensing
authors.forename: Marius
authors.initials: M
authors.lastname: Kunze
authors.forename: Martina
authors.initials: M
authors.lastname: Zöller
authors.forename: Christian
authors.initials: C
authors.lastname: Roos
authors.forename: Albrecht F
authors.initials: AF
authors.lastname: Kiderlen
authors.forename: Carsten
authors.initials: C
authors.lastname: Ludwig
authors.forename: Franz-Josef
authors.initials: FJ
authors.lastname: Kaup
mesh_terms: D000562:Amebiasis / Q000175:diagnosis / Q000401:mortality / Q000469:parasitology / Q000662:veterinary*; D000818:Animals; D018420:Ape Diseases / Q000401:mortality / Q000469:parasitology*; D059611:Balamuthia mandrillaris / Q000302:isolation & purification*; D001921:Brain / Q000469:parasitology / Q000473:pathology*; D020808:Central Nervous System Protozoal Infections / Q000175:diagnosis / Q000401:mortality / Q000469:parasitology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D005858:Germany; D006071:Gorilla gorilla / Q000469:parasitology*; D008856:Microscopy, Fluorescence / Q000662:veterinary; D012336:RNA, Ribosomal, 16S / Q000032:analysis
chemical_list: D012336:RNA, Ribosomal, 16S