title: Amine-linked N-heterocyclic carbenes: the importance of an pendant free-amine auxiliary in assisting the catalytic reaction.
abstract: We have successfully expanded the library of amino-NHCs with varying substituents on the amine group, leading to insight about the instability of NHCs arising from the intermolecular interaction of the dangling amine side-arm. However, the pendant amine plays an important role with respect to the catalytic process, resuscitating the catalytic activity of unsaturated NHC's through a synergistic effect invoked by the secondary amine. This proof of concept allows us to expand the spectrum of catalysis to C-C, as well as C-B bond formation.
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China.
authors.forename: Chia-Yi
authors.initials: CY
authors.lastname: Li
authors.forename: Yi-Yin
authors.initials: YY
authors.lastname: Kuo
authors.forename: Jie-Hong
authors.initials: JH
authors.lastname: Tsai
authors.forename: Glenn P A
authors.initials: GP
authors.lastname: Yap
authors.forename: Tiow-Gan
authors.initials: TG
authors.lastname: Ong