title: Lesions of the lacrimal caruncle with an emphasis on oncocytoma.
abstract: Lesions of the lacrimal caruncle vary widely due to its unique composition. Rarely, dermatologists and dermatopathologists encounter biopsies taken from this location. The aims of this study were to (1) retrospectively review caruncular lesions of the eye examined at Duke University Medical Center and (2) review the literature associated with caruncle pathology with emphasis on oncocytoma. A retrospective search of all lesions of the caruncle examined at Duke University Medical Center from 1991 to 2009 was performed. Fifty-nine lesions of the caruncle were identified. Nevi (40.7%) were the most common lesions observed, although squamous papillomas were the second most common entity (8.5%). Three oncocytomas were identified (5.1%), and were the next most common lesion present at this body site. These 3 entities represented 54.3% of the lesions found in the caruncle. Fifteen percent of the caruncular biopsies contained malignant or borderline malignant lesions, whereas the remaining 85% were benign entities. Most lesions present in the caruncle are benign. Although relatively rare, oncocytomas may be encountered by the dermatopathologist and may be confused for other neoplasms. Oncocytomas should be considered in the differential diagnosis based on this location in addition to histopathologic features.
authors.affiliation: Department of Pathology, The George Washington University, Washington, DC, USA.
authors.forename: Jyoti P
authors.initials: JP
authors.lastname: Kapil
authors.forename: Alan D
authors.initials: AD
authors.lastname: Proia
authors.forename: Puja Kumari
authors.initials: PK
authors.lastname: Puri
mesh_terms: D018249:Adenoma, Oxyphilic / Q000473:pathology*; D003937:Diagnosis, Differential; D007766:Lacrimal Apparatus Diseases / Q000473:pathology*