title: Identification of false-positive syphilis antibody results using a semiquantitative algorithm.
abstract: Screening patients for syphilis serology using a "treponemal assay-first" approach presents unique challenges, particularly when applied to low-prevalence populations. The use of a screening algorithm that incorporates semiquantitative values from treponemal antibody test results can help to identify potential false-positive results while requiring a minimum of repeat testing.
authors.affiliation: Section of Immunopathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Belinda
authors.initials: B
authors.lastname: Yen-Lieberman
authors.forename: Juliet
authors.initials: J
authors.lastname: Daniel
authors.forename: Cathy
authors.initials: C
authors.lastname: Means
authors.forename: Joan
authors.initials: J
authors.lastname: Waletzky
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Daly
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D019411:Clinical Laboratory Techniques / Q000379:methods*; D005189:False Positive Reactions; D006801:Humans; D008403:Mass Screening / Q000379:methods; D012698:Serologic Tests / Q000379:methods; D013587:Syphilis / Q000175:diagnosis*
chemical_list: D000907:Antibodies, Bacterial