title: (5S)-3-Chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-5-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]furan-2(5H)-one.
abstract: The title compound, C(18)H(26)ClNO(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of 3,4-dichloro-5-(S)-(l-menth-yloxy)furan-2(5H)-one and 2,5-di-hydro-1H-pyrrole in the presence of potassium fluoride. In the mol-ecule, the nearly planar dihydro-pyrrole ring [maximum atomic deviation = 0.019 (3) Å] is oriented at a dihedral angle of 10.73 (8)° to the the nearly planar furan-one ring [maximum atomic deviation = 0.011 (2) Å]; the cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked via weak inter-molecular C-H⋯O hydrogen bonds, forming supra-molecular chains running along the b axis.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Fu
authors.forename: Zhao-Yang
authors.initials: ZY
authors.lastname: Wang
authors.forename: Fu-Ling
authors.initials: FL
authors.lastname: Xue
authors.forename: Jing-Pei
authors.initials: JP
authors.lastname: Huo