title: [Acquired nystagmus in a 12-year-old boy as initial presentation of Lyme disease].
abstract: We report the case of a 12-year-old boy presenting with acquired horizontal nystagmus, headaches, and vertigo. CT, MRI, viral tests, and the Lyme disease test were at first negative. We made the diagnosis of neuroborreliosis based on a repeated Lyme disease test and lumbar puncture revealing intrathecal synthesis of specific antibodies. Adjusted antibiotic treatment led to complete disappearance of symptoms. Lyme borreliosis is difficult to diagnose and should be sought in case of unusual neuro-ophthalmic signs, especially in children.
authors.affiliation: Service d'ophtalmologie, centre hospitalier régional d'Orléans, 14, avenue de l'Hôpital, 45067 Orléans cedex 02, France. sp.samimi@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Samimi
authors.forename: S
authors.initials: S
authors.lastname: Salah
authors.forename: P
authors.initials: P
authors.lastname: Bonicel
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood / Q000134:cerebrospinal fluid; D015153:Blotting, Western; D025065:Borrelia burgdorferi / Q000276:immunology; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D004172:Diplopia / Q000209:etiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D006261:Headache / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D020852:Lyme Neuroborreliosis / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008279:Magnetic Resonance Imaging; D008297:Male; D009759:Nystagmus, Pathologic / Q000209:etiology*; D012680:Sensitivity and Specificity; D013129:Spinal Puncture; D014717:Vertigo / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D002443:Ceftriaxone