title: Zinc triflate catalyzed aerobic cross-dehydrogenative coupling (CDC) of alkynes with nitrones: a new entry to isoxazoles.
abstract: A mild, operationally simple cross-dehydrogenative coupling between nitrones and terminal alkynes is described by using cheap, readily available 3,3',5,5'-tetra-tert-butyldipheno-quinone and dioxygen as oxidants. These cross-couplings can be performed on various nitrones and alkynes with good to excellent yields. Product nitrones are readily transformed to pharmaceutically important 3,5-disubstituted isoxazoles.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Münster, Germany.
authors.forename: Sandip
authors.initials: S
authors.lastname: Murarka
authors.forename: Armido
authors.initials: A
authors.lastname: Studer