title: Neonatal outcome in hypertensive disorders of pregnancy.
abstract: BACKGROUND
  Hypertensive disorders in pregnancy account for increased perinatal morbidity and mortality when compared to uneventful gestations.
  
  
  OBJECTIVE
  To analyze perinatal outcome of pregnancies complicated by different kinds of hypertension to uncomplicated pregnancies in a series of Italian women and to compare our data with series from other countries.
  
  
  METHODS
  The sample was divided into four groups of hypertensive women: chronic hypertension (CH), gestational hypertension (GH), preeclampsia (PE), and chronic hypertension complicated by preeclampsia (CHPE). One thousand normal pregnancies served as controls.
  
  
  METHODS
  Neonatal features of the offspring of 965 Italian women with hypertension in pregnancy were evaluated.
  
  
  METHODS
  Gestational age, birthweight and the rate of small for gestational age were the outcomes. Perinatal asphyxia and mortality were also assessed.
  
  
  RESULTS
  Gestational age, the mean of birth weight and birth percentile were significantly lower in all groups with hypertensive complications when compared with controls. The rate of very early preterm delivery (<32 weeks) was 7.8% in CH, 5.9% in GH, 21.2% in PE and 37.2% in CHPE while it was to 1.2% in the control group. The rate of SGA was globally 16.2% in CH, 22.8% in GH, 50.7% in PE, 37.2% in CHPE and 5% in controls. The rate of SGA in PE was much higher than reported in series from other countries.
  
  
  CONCLUSIONS
  Comparing our data with those reported from other countries, it is evident that the rate of fetal growth restriction in PE we found in our center, is significantly higher even in the presence of a global lower incidence of PE.
authors.affiliation: Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Ferrazzani
authors.forename: Rita
authors.initials: R
authors.lastname: Luciano
authors.forename: Serafina
authors.initials: S
authors.lastname: Garofalo
authors.forename: Vito
authors.initials: V
authors.lastname: D'Andrea
authors.forename: Sara
authors.initials: S
authors.lastname: De Carolis
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: De Carolis
authors.forename: Valentina
authors.initials: V
authors.lastname: Paolucci
authors.forename: Costantino
authors.initials: C
authors.lastname: Romagnoli
authors.forename: Alessandro
authors.initials: A
authors.lastname: Caruso
mesh_terms: D000328:Adult; D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies