title: Grand rounds: The opportunity for and challenges to malaria eradication.
abstract: In 2009, malaria, a disease transmitted by the bite of an infective Anopheles mosquito, caused an estimated 225 million clinical cases and 781,000 deaths worldwide, of which more than 90% occurred in children aged <5 years in Africa. Approximately half of the world's population, or 3 billion persons, are at risk for acquiring the illness. Malaria is transmitted most intensely in central and western Africa, where in some areas >40% of children aged <10 years are infected and residents can be bitten by more than one infective mosquito every day of the year.
mesh_terms: D000328:Adult; D000349:Africa / Q000453:epidemiology; D000962:Antimalarials / Q000627:therapeutic use; D037621:Artemisinins / Q000627:therapeutic use; D002648:Child; D017281:Cost of Illness; D005260:Female; D014943:Global Health; D006801:Humans; D057148:Insecticide-Treated Bednets; D007306:Insecticides / Q000008:administration & dosage; D008288:Malaria / Q000453:epidemiology* / Q000517:prevention & control*; D017780:Malaria Vaccines; D011247:Pregnancy
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D007306:Insecticides; D017780:Malaria Vaccines; C031327:artemisinin