title: Gold nanoparticles enhancing dismutation of superoxide radical by its bis(dithiocarbamato)copper(II) shell.
abstract: In the past few years three topics in nanoscience have received great attention: catalytic activity of gold nanoparticles (AuNPs), their electron transfer properties, and magnetism. Although these properties could have much in common no report on their synergism has been published. Here we present 10-nm gold nanoparticles conveniently capped with a mixed self-assembled monolayer containing bis(dithiocarbamato)copper(II) complexes, which dismutate superoxide radical with extremely high efficiency (IC(50) = 0.074 μM). This behavior is interpreted as the result of an electron transfer (ET) process between AuNP core and the analyte when associated to copper(II). The ET process involving a charged AuNP core was detected by EPR and UV-vis spectroscopy.
authors.affiliation: Lab. Bioinorgánica, Facultad de Química, Universidad de La Habana, Zapata y G, Vedado, La Habana 10400, Cuba.
authors.forename: Roberto
authors.initials: R
authors.lastname: Cao
authors.forename: Reynaldo
authors.initials: R
authors.lastname: Villalonga
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Díaz-García
authors.forename: Roberto
authors.initials: R
authors.lastname: Cao
authors.forename: Teofilo
authors.initials: T
authors.lastname: Rojo
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Rodríguez-Argüelles
mesh_terms: D003300:Copper / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010316:Particle Size; D013481:Superoxides / Q000737:chemistry*; D013499:Surface Properties; D013859:Thiocarbamates / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D013859:Thiocarbamates; D013481:Superoxides; D006046:Gold; D003300:Copper