title: [Experimental study on stability of temporomandibular joint replacement].
abstract: OBJECTIVE
  To discuss the stability and practicality of temporomandibular joint replacement by establishing goats artificial temporomandibular joint replacement model.
  
  
  METHODS
  Six healthy mature goats were selected, the male and female being half and weighing 35.3-37.0 kg. According to the parameters from X-ray films of goat's temporomandibular joint and the shape of the same kind goat's skull, the total temporomandibular joint prosthesis was prepared. The one side temporomandibular joints of six goats were replaced by prosthesis randomly as the experimental group (n = 6, fossa and condyle according to replacement location) and the other side by titanium plate as the control group (n = 6). At 4, 8, and 12 weeks, the histological observation, scanning electron microscope (SEM) observation were carried out for observing structural changes in the interface. The mechanical test and histochemistry test were used for observing the combination degree of interface and the alkaline phosphatase (ALP) activity.
  
  
  RESULTS
  All animals were alive to the end of experiment with normal open mouth, good recovery of masticatory function, and normal eating. At 4, 8, and 12 weeks, implants were stable in 2 groups without loosening. The histological observation and SEM observation showed the amount of osteoblasts in interface increased over times. There were significant differences in the shearing force and the ALP activity between fossa in experimental group and control group at 4 weeks (P < 0.05), but there was no significant difference between other groups (P > 0.05).
  
  
  CONCLUSIONS
  The total temporomandibular prosthesis has good stability in temporomandibular joint reconstruction of goat after replacement.
authors.affiliation: Oral Teaching and Research Section of Shenyang Medical College, Shenyang Liaoning, 110034, P.R.China.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Yi
authors.initials: Y
authors.lastname: Sun
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhou
mesh_terms: D000818:Animals; D019643:Arthroplasty, Replacement / Q000295:instrumentation* / Q000379:methods*; D005260:Female; D006041:Goats; D007595:Joint Prosthesis; D008297:Male; D013704:Temporomandibular Joint / Q000502:physiology* / Q000601:surgery*