title: Prostate adenocarcinoma with orbital metastasis in an HIV+ man.
abstract: BACKGROUND
  To report an unusual presentation of metastatic prostate cancer to the orbit in an immunosuppressed patient, who received a novel palliative treatment regimen.
  
  
  METHODS
  A 56 year old HIV+ man presented with proptosis and unilateral blindness. The diagnosis, work up, and treatment are outlined.
  
  
  RESULTS
  Metastatic prostate cancer to the orbit is diagnosed, and the treatment with IMRT and hormone ablation is explored.
  
  
  CONCLUSIONS
  We outline the literature and current thinking surrounding prostate cancer metastases to the orbit. HIV+ patients currently enjoy longer life expectancies, with the caveat that their immunosuppressed status may lead to more unusual metastatic presentations. Treatments and palliation will continue to evolve as these new cases emerge.
authors.affiliation: Department of Urology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
authors.forename: Jay
authors.initials: J
authors.lastname: Heintz
authors.forename: Barbara
authors.initials: B
authors.lastname: Kahn
authors.forename: Andrew
authors.initials: A
authors.lastname: Kramer
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D000813:Anilides / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D006679:HIV Seropositivity / Q000276:immunology*; D006801:Humans; D016867:Immunocompromised Host; D016729:Leuprolide / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use; D009918:Orbital Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D010166:Palliative Care; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D050397:Radiotherapy, Intensity-Modulated; D014105:Tosyl Compounds / Q000627:therapeutic use
chemical_list: D000813:Anilides; D000970:Antineoplastic Agents; D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014105:Tosyl Compounds; C053541:bicalutamide; D016729:Leuprolide