title: Chromones and coumarins from the dried fructus of Cnidium monnieri.
abstract: Chemical investigations on the ethanolic extract of the dried fructus of Cnidium monnieri offered three chromones and eight coumarins. Among them, a new chromone and a new coumarin were identified and elucidated as 5,7-dihydroxy-6-[(2Z)-4-(β-d-glucopyranosyl)oxy-3- methylbut-2-enyl]-2-hydroxymethyl-4H-1-benzopyran-4-one (1, hydroxycnidimoside A) and (rel 1'S,2'R)-8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin (8, hydroxyosthole epoxide), respectively, by extensive analyses of spectroscopic data including 1- and 2-D NMR, MS, UV, OR, IR, and HRMS data. The other known compounds were identified by analyses of spectroscopic data and by comparison with literature reported.
authors.affiliation: Center for Natural Products Research, Chengdu Institute of Biology of the Chinese Academy of Sciences, P.R. China.
authors.forename: Jianyu
authors.initials: J
authors.lastname: Zhao
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Guolin
authors.initials: G
authors.lastname: Zhang
authors.forename: Yinggang
authors.initials: Y
authors.lastname: Luo
mesh_terms: D002867:Chromones / Q000737:chemistry / Q000302:isolation & purification*; D031048:Cnidium / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D005638:Fruit; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: C568431:(1'S,2'R)-8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin; C568432:5,7-dihydroxy-6-((2Z)-4-(beta-D-glucopyranosyl)oxy-3- methylbut-2-enyl)-2-hydroxymethyl-4H-1-benzopyran-4-one; D002867:Chromones; D003374:Coumarins; D010936:Plant Extracts