title: The emerging world of small silencing RNAs in protozoan parasites.
abstract: A new RNA world has emerged in the past 10 years with the discovery of a plethora of 20- to 30-nucleotide long small RNAs that are involved in various gene silencing mechanisms. These small RNAs have considerably changed our view of the regulation of gene expression in eukaryotic organisms, with a major shift towards epigenetic and post-transcriptional mechanisms. In this article, we focus on the striking diversity of small silencing RNAs that have been identified in several protozoan parasites and their potential biological role.
authors.affiliation: Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06536, USA.
authors.forename: Vanessa D
authors.initials: VD
authors.lastname: Atayde
authors.forename: Christian
authors.initials: C
authors.lastname: Tschudi
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Ullu
mesh_terms: D000818:Animals; D056890:Eukaryota / Q000235:genetics* / Q000378:metabolism*; D020868:Gene Silencing / Q000502:physiology*; D034741:RNA, Small Interfering / Q000235:genetics / Q000276:immunology*
chemical_list: D034741:RNA, Small Interfering