title: Signaling gateway molecule pages--a data model perspective.
abstract: CONCLUSIONS
  The Signaling Gateway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in different functional states participating in signal transduction pathways. A molecule page starts with astate of a native protein, without any modification and/or interactions. New states are formed with every post-translational modification or interaction with one or more proteins, small molecules or class molecules and with each change in cellular location. State transitions are caused by a combination of one or more modifications, interactions and translocations which then might be associated with one or more biological processes. In a characterized biological state, a molecule can function as one of several entities or their combinations, including channel, receptor, enzyme, transcription factor and transporter. We have also exported SGMP data to the Biological Pathway Exchange (BioPAX) and Systems Biology Markup Language (SBML) as well as in our custom XML.
  
  
  BACKGROUND
  SGMP is available at www.signaling-gateway.org/molecule.
authors.affiliation: Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.
authors.forename: Ashok Reddy
authors.initials: AR
authors.lastname: Dinasarapu
authors.forename: Brian
authors.initials: B
authors.lastname: Saunders
authors.forename: Iley
authors.initials: I
authors.lastname: Ozerlat
authors.forename: Kenan
authors.initials: K
authors.lastname: Azam
authors.forename: Shankar
authors.initials: S
authors.lastname: Subramaniam
mesh_terms: D030562:Databases, Protein; D020407:Internet; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D015398:Signal Transduction
chemical_list: D047908:Intracellular Signaling Peptides and Proteins