title: Oral agents in cancer treatment: the context for adherence.
abstract: OBJECTIVE
  To review oral agents approved for cancer, discuss their mechanism of action and/or molecular targets, and outline side effects and challenges that impact adherence.
  
  
  METHODS
  Peer reviewed literature and on-line drug information.
  
  
  CONCLUSIONS
  Oral agents to treat cancer, although not new, are common and increasing dramatically. The context of adherence to oral agents is complicated by increased knowledge of food-drug interactions and combinations of agents with overlapping or synergistic toxicity profiles.
  
  
  CONCLUSIONS
  The role of nursing in the administration and education of oral cancer treatments is critical to optimal treatment outcomes.
authors.affiliation: Oncology, Mayo Clinic, 200 First Street SW, Charlton 6-133, Rochester, MN 55905, USA. barton.debra@mayo.edu
authors.forename: Debra
authors.initials: D
authors.lastname: Barton
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D010349:Patient Compliance
chemical_list: D000970:Antineoplastic Agents