title: Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; synthesis of dimebolin.
abstract: A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl azides. Other catalysts and conditions were neither as selective nor as high-yielding. This method was used to synthesize dimebolin in a concise and efficient manner.
authors.affiliation: Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607-7061, United States.
authors.forename: Huijun
authors.initials: H
authors.lastname: Dong
authors.forename: Regina T
authors.initials: RT
authors.lastname: Latka
authors.forename: Tom G
authors.initials: TG
authors.lastname: Driver
mesh_terms: D001386:Azides / Q000737:chemistry*; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D001386:Azides; D002243:Carbolines; D007211:Indoles; C055572:gamma-carboline; D012428:Ruthenium; C010119:latrepirdine