title: [Alternatives to allogenous blood transfusion].
abstract: Blood transfusion is usually meant to lower morbidity and mortality rates. Allogenous blood transfusion implies certain risks that can be avoided by autologous blood transfusions techniques including: preoperatory autologous blood donation, acute normovolemic hemodilution, intraoperatory and postoperatory blood salvage. Preoperatory blood donation and acute normovolemic hemodilution are used for planned interventions with an estimated blood loss higher than 20% of blood volume. These methods imply Erythropoietin and iron treatment. Intraoperatory and postoperatory blood salvage is performed by personnel trained in blood donation, handling and storage. Autologous blood transfusions are used for certain surgical procedures that commonly require transfusions: orthopedic surgery, radical prostatectomy, cardiovascular surgery, organ transplantation. An alternative to allogenous blood transfusion is the use of artificial oxygen transporters: human or animal hemoglobin solutions or pefluorocarbonate solutions. These solutions do not require cross reactions, do not carry diseases and are generally well tolerated and easily stored in the operating room, ambulance and other transport means. They have however a slight degree of toxicity.
authors.affiliation: Disciplina de ATI, Facultatea de Medicină, Universitatea de Medicină si Farmacie Craiova.
authors.forename: Daniela
authors.initials: D
authors.lastname: Cernea
authors.forename: Alice
authors.initials: A
authors.lastname: Vlădoianu
authors.forename: Maria
authors.initials: M
authors.lastname: Stoica
authors.forename: M
authors.initials: M
authors.lastname: Novac
authors.forename: Cristina
authors.initials: C
authors.lastname: Berteanu
mesh_terms: D001782:Blood Donors; D001802:Blood Substitutes / Q000008:administration & dosage; D001803:Blood Transfusion / Q000379:methods; D001804:Blood Transfusion, Autologous / Q000379:methods; D004921:Erythropoietin / Q000008:administration & dosage; D006438:Hemodilution / Q000379:methods; D006801:Humans; D007430:Intraoperative Care; D007501:Iron / Q000008:administration & dosage; D011189:Potassium Chloride / Q000008:administration & dosage; D011300:Preoperative Care / Q000379:methods; D014184:Transplantation, Homologous
chemical_list: D001802:Blood Substitutes; D004921:Erythropoietin; D011189:Potassium Chloride; D007501:Iron