title: [Bariatric surgery as a treatment of type 2 diabetes].
abstract: Obesity has reached epidemic proportions, predisposing to the development of type 2 diabetes and cardiovascular diseases. Weight loss is a major objective, although often difficult to achieve with medical treatments. Bariatric surgery has proven its efficacy in obtaining marked and sustained weight loss, and is also associated with a significant improvement in insulin resistance, beta cell function, lipid metabolism, blood pressure and even diabetes remission. We examined the long-term effect of Roux-en-Y gastric bypass (RYGB, a predominantly restrictive procedure) in a patient with uncontrolled type 2 diabetes. One year after surgery, the patient had lost 30% of initial weight with a significant improvement in blood pressure, withdrawal of cholesterol-lowering therapy, complete remission of diabetes.
authors.affiliation: Dipartimento di Medicina Interna, Università di Pisa.
authors.forename: Stefania
authors.initials: S
authors.lastname: Camastra
authors.forename: Chiara
authors.initials: C
authors.lastname: Chiellini
authors.forename: Roberta
authors.initials: R
authors.lastname: Petz
authors.forename: Amalia
authors.initials: A
authors.lastname: Gastaldelli
authors.forename: Ele
authors.initials: E
authors.lastname: Ferrannini
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000601:surgery*; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications / Q000601:surgery*