title: Shigella targets T cells.
abstract: Using a syringe-like device, Shigella delivers an array of virulence factors into host cells to facilitate bacterial colonization and disable the host's innate immune defense. In this issue of Cell Host & Microbe, Konradt and colleagues (Konradt et al., 2011) show that Shigella also subverts adaptive immunity by targeting T cells through a mechanism involving PIP(2) breakdown.
authors.affiliation: Novartis Vaccines, Siena, Italy.
authors.forename: John L
authors.initials: JL
authors.lastname: Telford
authors.forename: Cosima T
authors.initials: CT
authors.lastname: Baldari