title: Disseminated Burkholderia gladioli infection in a lung transplant recipient with underlying hypocomplementemic urticarial vasculitis.
abstract: Burkholderia gladioli is difficult to definitively identify within the laboratory using phenotypic testing alone. We describe a case of recurrent B. gladioli infection in a lung transplant recipient with underlying hypocomplementemic urticarial vasculitis syndrome, discuss the difficulties encountered with laboratory identification, provide a review of the methodology required for definitive identification, and discuss potential pathophysiologic mechanisms in this patient responsible for the difficulty in treatment.
authors.affiliation: Department of Medical Microbiology and Immunology, Division of Infectious Diseases, University of California-Davis, Davis, California 95616, USA. george.thompson@ucdmc.ucdavis.edu
authors.forename: G R
authors.initials: GR
authors.lastname: Thompson
authors.forename: B L
authors.initials: BL
authors.lastname: Wickes
authors.forename: M L
authors.initials: ML
authors.lastname: Herrera
authors.forename: T C
authors.initials: TC
authors.lastname: Haman
authors.forename: J S
authors.initials: JS
authors.lastname: Lewis
authors.forename: J H
authors.initials: JH
authors.lastname: Jorgensen
mesh_terms: D019121:Burkholderia Infections / Q000150:complications / Q000175:diagnosis*; D042725:Burkholderia gladioli / Q000302:isolation & purification; D003165:Complement System Proteins / Q000276:immunology; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008875:Middle Aged; D011183:Postoperative Complications; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000276:immunology; D013577:Syndrome; D056647:Systemic Vasculitis / Q000150:complications / Q000276:immunology; D014581:Urticaria / Q000150:complications / Q000276:immunology
chemical_list: D003165:Complement System Proteins