title: Genotypic characterization of Iranian camel (Camelus dromedarius) isolates of Echinoccocus granulosus.
abstract: In the present study, Echinoccocus granulosus isolates collected from camels (Camelus dromedarius) in eastern Iran were characterized based on the nucleotide sequences of mitochondrial CO1 and NDI genes. The molecular results for camel isolates demonstrated that at least 2 different genotypes are present, i.e., a buffalo genotype (G3) and the camel genotype (G6). Although the sequences of the Iranian camel genotype (G6) are completely homologous to the reference sequence of G6 (M84666) of E. granulosus , a nucleotide mutation (C to T at position 168) was detected in the CO1 sequences of the Iranian G3 isolates (HM626405) when compared with the reference G3 genotype (M84663). The findings of the present study represent the demonstration of the buffalo strain in camels. As previously reported, humans can be infected by this genotype; accordingly, the epidemiological importance of this genotype in the camel population should be considered in further studies.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, P.O. Box 1731, Shiraz 71345, Iran. sharifiy@shirazu.ac.ir
authors.forename: Hassan
authors.initials: H
authors.lastname: Sharifiyazdi
authors.forename: Ahmad
authors.initials: A
authors.lastname: Oryan
authors.forename: Sara
authors.initials: S
authors.lastname: Ahmadnia
authors.forename: Akbar
authors.initials: A
authors.lastname: Valinezhad
mesh_terms: D000818:Animals; D001483:Base Sequence; D002162:Camelus / Q000469:parasitology*; D051545:Cyclooxygenase 1 / Q000235:genetics; D018509:DNA, Helminth / Q000737:chemistry; D004443:Echinococcosis / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D048209:Echinococcus granulosus / Q000145:classification* / Q000235:genetics; D005260:Female; D005838:Genotype; D007492:Iran / Q000453:epidemiology; D008099:Liver / Q000469:parasitology; D008168:Lung / Q000469:parasitology; D008297:Male; D009245:NADH Dehydrogenase / Q000235:genetics; D010802:Phylogeny; D015995:Prevalence; D016415:Sequence Alignment / Q000662:veterinary; D017678:Sex Distribution; D013154:Spleen / Q000469:parasitology
chemical_list: D018509:DNA, Helminth; D051545:Cyclooxygenase 1; D009245:NADH Dehydrogenase