title: [Effect of Tween 80 on yuxingcao injection and volatile oils from Houttuynia cordata].
abstract: OBJECTIVE
  To research the effect of polysorbate 80 (Tween 80) on Yuxingcao injection and volatile oils from Houttuynia cordata.
  
  
  METHODS
  1H-NMR spectra of aldehydic and new matter in Yuxingcao injection, volatile oils of H. cordata, and solutions of Tween 80 and volatile oil of H. cordata are determined and compared from various angles of growing origin, storage temperature, and storage time.
  
  
  RESULTS
  Three aldehydic singlets in 1H-NMR spectra of every volatile oil from 4 aerial part of H. cordata were observed. These aldehydic peaks were basically disappeared and a new peak at delta 8.30 was found in 1H-NMR spectra of the volatile oil solutions in tween 80. Any obvious aldehydic peak in 1H-NMR spectra did not be observed in Yuxincao injection. A weak peak at 8 8.30 was found in 1H-NMR spectra in Yuxincao injection, and the peak high of delta 8.30 was remarked gone up when the injection was stored in 40 degrees C for 1 to 3 months.
  
  
  CONCLUSIONS
  Tween 80 might cause the obvious reduce of aldehydic compounds contents and the production of a novel singal at delta 8.30 in 1H-NMR spectra when it was mixed with the volatile oil from the aerial part of H. cordata. The novel signal at delta 8.30 in 1H-NMR spectra existed in Yuxincao injection and was very small, but was increased remarkably when the Yuxincao injection was stored at 40 degrees C for 1 month at least.
authors.affiliation: Experimental Research Center, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Zhigao
authors.initials: Z
authors.lastname: Tan
authors.forename: Zhimao
authors.initials: Z
authors.lastname: Chao
authors.forename: Yu
authors.initials: Y
authors.lastname: Sui
authors.forename: Haiping
authors.initials: H
authors.lastname: Liu
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Wu
authors.forename: Jian
authors.initials: J
authors.lastname: Sun
authors.forename: Han
authors.initials: H
authors.lastname: Yan
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D052859:Houttuynia / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*; D011136:Polysorbates; D013696:Temperature
chemical_list: D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D010938:Plant Oils; D011136:Polysorbates