title: Calcinosis cutis of the hand in a renal failure patient: a case report.
abstract: A 25-year-old woman with end-stage renal failure presented with subcutaneous calcinosis cutis that grew rapidly in both hands. Radiographs showed subcutaneous lobulated calcific deposits. Magnetic resonance imaging revealed a heterogeneous mass encasing segments of the abductor pollicis longus and extensor pollicis brevis tendons. Excision of the masses was performed. Histopathology revealed amorphous calcified deposits in fibrous tissue and a foreign body reaction. There was no evidence of a tubercular lesion. Further investigation revealed the presence of hyperphosphataemia and secondary hyperparathyroidism, despite a normal serum calcium level. Oral phosphate-lowering agents failed to control the condition, and recurrence was noted 6 months later. The patient finally underwent parathyroidectomy and has had no further recurrence.
authors.affiliation: Department of Orthopaedics and Traumatology, Kwong Wah Hospital, Hong Kong. aslyip@gmail.com
authors.forename: Siu-Leung
authors.initials: SL
authors.lastname: Yip
authors.forename: Siu-Cheong
authors.initials: SC
authors.lastname: Koo
authors.forename: Chi-Hung
authors.initials: CH
authors.lastname: Yen
authors.forename: Kan-Hing
authors.initials: KH
authors.lastname: Mak
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002115:Calciphylaxis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006225:Hand; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D019637:Orthopedic Procedures / Q000379:methods