title: The epidemiology of osteoarthritis in Asia.
abstract: Worldwide, osteoarthritis (OA) is estimated to be the fourth leading cause of disability. Most of this disability burden is attributable to the involvement of the hips or the knees. OA is strongly associated with ageing and the Asian region is ageing rapidly. Further, OA has been associated with heavy physical occupational activity, a required livelihood for many people living in rural communities in developing countries. Unfortunately, joint replacement surgery, an effective intervention for people with severe OA involving the hips or knees, is inaccessible to most people in these regions. On the other hand, obesity, another major risk factor, may be less prevalent, although it is on the increase. Determining region-specific OA prevalence and risk factor profiles will provide important information for planning future cost-effective preventive strategies and health care services. An update of what is currently known about the prevalence of hip and knee OA from population-based studies conducted in the Asian region is presented in this review. Many of the recent studies have conducted comparisons between urban and rural areas and poor and affluent communities. The results of Asian-based studies evaluating risk factors from population-based cohorts or case-control studies, and the current evidence on OA morbidity burden in Asia is also outlined.
authors.affiliation: Faculty of Health Sciences, School of Medicine, University of Sydney, Sydney, New South Wales School of Population Health, University of Queensland, Brisbane, Queensland, Australia.
authors.forename: Marlene
authors.initials: M
authors.lastname: Fransen
authors.forename: Lisa
authors.initials: L
authors.lastname: Bridgett
authors.forename: Lyn
authors.initials: L
authors.lastname: March
authors.forename: Damian
authors.initials: D
authors.lastname: Hoy
authors.forename: Ester
authors.initials: E
authors.lastname: Penserga
authors.forename: Peter
authors.initials: P
authors.lastname: Brooks
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001208:Asia / Q000453:epidemiology; D044466:Asian People / Q000706:statistics & numerical data*; D004185:Disability Evaluation; D005260:Female; D006621:Hip Joint / Q000503:physiopathology; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology / Q000628:therapy; D020370:Osteoarthritis, Knee / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology / Q000503:physiopathology / Q000628:therapy; D015995:Prevalence; D011379:Prognosis; D012111:Residence Characteristics; D012307:Risk Factors; D055815:Young Adult