title: Hemophilic arthropathy of the elbow.
abstract: Hemophilia is a hereditary disease in which circulating levels of coagulation factors are lacking, resulting in a propensity toward bleeding. Intra-articular hemorrhages are a hallmark of hemophilia and may lead a cascade of cytokine elaboration and inflammatory-mediated changes, which ultimately result in cartilage loss and arthropathy. Diarthrodial joints, such as the knee, elbow, and ankle, are most commonly affected. This article highlights issues surrounding hemophilic arthropathy of the elbow and focuses on preventive measures, management strategies of the hemophilic elbow, and treatment options for established arthropathy.
authors.affiliation: Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Avenue, R200, Minneapolis, MN 55454, USA. adams854@umn.edu
authors.forename: Julie E
authors.initials: JE
authors.lastname: Adams
authors.forename: Mark T
authors.initials: MT
authors.lastname: Reding
mesh_terms: D001168:Arthritis / Q000473:pathology / Q000503:physiopathology; D057929:Arthroplasty, Replacement, Elbow; D002358:Cartilage, Articular / Q000378:metabolism / Q000473:pathology; D003646:Debridement; D004551:Elbow Joint / Q000000981:diagnostic imaging / Q000473:pathology; D006467:Hemophilia A / Q000150:complications* / Q000503:physiopathology; D006470:Hemorrhage / Q000503:physiopathology; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D000074402:Synovectomy; D013583:Synovial Membrane / Q000473:pathology; D014057:Tomography, X-Ray Computed