title: [Release of CD44-proteolytic fragments and their functions].
abstract: CD44 is a widely distributed cell-adhesion molecule that participates in a number of biological events. CD44 is proteolytically cleaved by other enzymes and the level of its proteolysis is correlated to the cell activity. The CD44-proteolytic peptides including soluble CD44 and CD44 intracellular domain have different functions in cell events. In recent years, a number of researches found the functions of CD44-proteolytic peptides. In this review, the release of CD44-proteolytic peptides and their functions of these peptides were summarized.
authors.affiliation: Department of Hematology, Nanfang Hospital, Nanfang Medical University, Guangzhou 510515, Guangdong Province, China.
authors.forename: Da-Yan
authors.initials: DY
authors.lastname: Chen
authors.forename: Ru
authors.initials: R
authors.lastname: Feng
mesh_terms: D018960:Hyaluronan Receptors / Q000378:metabolism*; D006868:Hydrolysis
chemical_list: D018960:Hyaluronan Receptors