title: Glycan profiling of gel forming mucus layer from the scleractinian symbiotic coral Oculina arbuscula.
abstract: The gel forming mucus layer surrounding scleractinian corals play fundamental functions in the maintenance of a favorable microenvironment required for the survival of these organisms. In particular, it harbors a rich partially species-specific symbiotic community through yet poorly understood molecular interactions. However, removal or contamination of this community by exogenous bacteria is closely linked to the worldwide bleaching events that are presently devastating coral colonies. The present study investigates the structure of major high molecular weight glycoconjugates that are responsible for both rheological properties of mucus and sugar-protein interactions with microbial communities. We demonstrated that it is composed by two distinct types of sulfated macromolecules: mucin type glycoproteins densely substituted by short unusual O-linked glycans and repetitive polysaccharides.
authors.affiliation: Université de Lille1 , Unité de Glycobiologie Structurale et Fonctionnelle, F-59650 Villeneuve d'Ascq, France.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Coddeville
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Maes
authors.forename: Christine
authors.initials: C
authors.lastname: Ferrier-Pages
authors.forename: Yann
authors.initials: Y
authors.lastname: Guerardel
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry* / Q000382:microbiology; D001419:Bacteria / Q000254:growth & development; D002240:Carbohydrate Sequence; D017753:Ecosystem; D005782:Gels / Q000737:chemistry; D006001:Glycoconjugates / Q000032:analysis / Q000737:chemistry*; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009077:Mucins / Q000032:analysis / Q000737:chemistry* / Q000145:classification; D011134:Polysaccharides / Q000032:analysis / Q000737:chemistry* / Q000145:classification; D013559:Symbiosis
chemical_list: D005782:Gels; D006001:Glycoconjugates; D009077:Mucins; D011134:Polysaccharides