title: [Preparation of xiongbing microemulsion and its quality evaluation].
abstract: OBJECTIVE
  To study the preparation of xiong-bing microemulsion (XB ME) and its quality evaluation.
  
  
  METHODS
  XB ME was prepared by using the methods of titration to prepare the Pseudo-ternary phase diagram. The stability and size distribution of XB ME were tested. The contents of TMP and FA in ME were determined by HPLC method.
  
  
  RESULTS
  The character of XB ME was stable. The average diameter was 17.6 nm, and a uniform distribution of particle size were achieved. The solubility of TMP in ME was 2.6 g x L(-1), the methodological average recovery was 97.0% with RSD of 1.5% (n=6); The solubility of FA in ME was 0.3 g x L(-1), the methodological average recovery was 95.9% with RSD of 1.9% (n=6).
  
  
  CONCLUSIONS
  The results indicated that the quality of XB ME was stable. The method to determine the contents of TMP and FA was accurate and reliable.
authors.affiliation: College of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. wlis68@126.com
authors.forename: Lisheng
authors.initials: L
authors.lastname: Wang
authors.forename: Qi
authors.initials: Q
authors.lastname: Guo
authors.forename: Yingfeng
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zongfeng
authors.initials: Z
authors.lastname: Shi
mesh_terms: D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry; D010316:Particle Size; D012995:Solubility
chemical_list: D004365:Drugs, Chinese Herbal; D004655:Emulsions