title: [Polycystic ovary syndrome--genetic considerations].
abstract: The Polycystic Ovarian Syndrome is one of the most frequent of the endocrinopathies, affecting in average 8% of the woman's that are in to reproductive age. It was first described by Chereau and Rokitanski, further associated with the amenorrhea encountered in the Stein and Levanthal syndrome, exposed by the Irving F, Stein and Michael Leventhal, in 1935. In many aspects this is a systemic disease also interfering with the process of reproduction. The studies of the genetic factor implication, by relating with the specialty literature, converging with a series of hypotesys launch over the years, show a poligenic affliction or a combination of the environment with the genetics factors. Due to the fact that this syndrome is the most frequently encountered cause of infertility among women's, with a very complex etiopathogeny, the comprehension of it, is most important, because the Polycystic Ovarian Syndrome is a metabolic long term disorder. The study of the genetic act implications is a name part in prophylaxis of the appearance of this syndrome or its complications.
authors.affiliation: Universităţii de Medicină si Farmacie Gr.T. Popa Iaşi.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Dumăchiţă-Gargu
authors.forename: Florentina
authors.initials: F
authors.lastname: Pricop
mesh_terms: D000568:Amenorrhea / Q000235:genetics; D004815:Epidermal Growth Factor / Q000235:genetics; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D007247:Infertility, Female / Q000235:genetics; D010375:Pedigree; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000453:epidemiology / Q000235:genetics* / Q000517:prevention & control; D015995:Prevalence; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D015291:Transforming Growth Factors / Q000235:genetics
chemical_list: D005819:Genetic Markers; D004815:Epidermal Growth Factor; D015291:Transforming Growth Factors