title: Temporal bone chondroblastoma with secondary aneurysmal bone cyst presenting as an intracranial mass with clinical seizure activity.
abstract: Chondroblastomas are rare tumors that characteristically arise from the epiphyseal cartilage of long bones of the immature skeleton. Intracranial involvement is uncommon, though the squamous portion of the temporal bone is preferentially affected due to its cartilaginous origin. Patients with temporal bone chondroblastomas classically present with otologic symptoms, while primary neurological complaints are rare. In this report, we describe a 33 year-old man with a chondroblastoma of the temporal bone and an associated aneurysmal bone cyst constituting a large intracranial mass lesion who presented with new-onset seizure activity. We review issues relevant to the pathology and treatment of these lesions.
authors.affiliation: Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Stapleton
authors.forename: Brian P
authors.initials: BP
authors.lastname: Walcott
authors.forename: Katy R
authors.initials: KR
authors.lastname: Linskey
authors.forename: Kristopher T
authors.initials: KT
authors.lastname: Kahle
authors.forename: Brian V
authors.initials: BV
authors.lastname: Nahed
authors.forename: Wael F
authors.initials: WF
authors.lastname: Asaad
mesh_terms: D000328:Adult; D017824:Bone Cysts, Aneurysmal / Q000473:pathology*; D001859:Bone Neoplasms / Q000150:complications* / Q000601:surgery; D002804:Chondroblastoma / Q000150:complications* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012640:Seizures / Q000209:etiology*; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods