title: N-methylimidazolium-functionalized monolithic silica column for mixed-mode chromatography.
abstract: The development of mixed-mode stationary phase to achieve multiple separation capabilities in one column is very important for high performance liquid chromatography. In this paper, a new specific stationary phase based on grafting N-methylimidazolium to a monolithic silica column was successfully prepared for performing capillary liquid chromatography. The characteristics of the column were evaluated by the separation of different types of compounds including inorganic anions, aromatic acids, nucleotides, polycyclic aromatic hydrocarbons, alkylbenzenes, and phenols. The mechanisms for the separation of these compounds were investigated and appeared to involve the mixed interactions including anion-exchange, hydrophilic, π-π, dipole-dipole, and hydrophobic interactions.
authors.affiliation: Ministry of Education Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Li
authors.initials: L
authors.lastname: Jia
mesh_terms: D000838:Anions / Q000302:isolation & purification; D053801:Capillary Electrochromatography / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007093:Imidazoles / Q000737:chemistry*; D007287:Inorganic Chemicals / Q000302:isolation & purification; D008855:Microscopy, Electron, Scanning; D008970:Molecular Weight; D009930:Organic Chemicals / Q000302:isolation & purification; D011137:Polystyrenes; D016062:Porosity; D015203:Reproducibility of Results; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D000838:Anions; D007093:Imidazoles; D007287:Inorganic Chemicals; D009930:Organic Chemicals; D011137:Polystyrenes; D012822:Silicon Dioxide; C018100:1-methylimidazole