title: [Different characteristics of quality of life in celiac disease patients].
abstract: OBJECTIVE
  To study quality of life (QoL) in patients with celiac disease (CD) in the course of treatment with aglutenic diet (AD).
  
  
  METHODS
  Modern algorithm of glutenic enteropathy diagnosis (enzyme immunoassay, histological examination of the biopsy of distal duodenum mucosa) was used in 650 patients with different gastrointestinal symptoms. QoL was assessed in the course of AD treatment of CD with application of universal standard questionnaire MOS SF-36.
  
  
  RESULTS
  CD was diagnosed in 56 (8.6%) patients. Classic CD was diagnosed in 44 (78.6%) patients, atypical CD--in 12 (21.4%). Significant lowering of QoL characteristic psychological health" was observed in CD patients under 30 and over 50 and "physical health" in 30-50-year-old CD patients. Women had low points on "mental health" scale. After 3 AD months QoL worsened by all the scales, but after 12 months QoL significantly improved.
  
  
  CONCLUSIONS
  QoL in patients with classic CD is associated with gender and age. First, AD deteriorates QoL, but 1-year diet therapy improves QoL.
authors.forename: E E
authors.initials: EE
authors.lastname: Moiseenko
authors.forename: M F
authors.initials: MF
authors.lastname: Osipenko
authors.forename: T A
authors.initials: TA
authors.lastname: Ageeva
authors.forename: S A
authors.initials: SA
authors.lastname: Krotov
authors.forename: N N
authors.initials: NN
authors.lastname: Burbik
mesh_terms: D000293:Adolescent; D000328:Adult; D002446:Celiac Disease / Q000178:diet therapy / Q000523:psychology*; D055050:Diet, Gluten-Free; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult