title: Synthesis of polysubstituted 5-azaindoles via palladium-catalyzed heteroannulation of diarylalkynes.
abstract: A general and efficient procedure for the synthesis of functionalized 5-azaindoles through the catalyzed heteroannulation of 4-acetamido-3-iodopyridines and diarylalkynes is described. The reaction allows the preparation of a variety of substituted 2,3-diaryl-5-azaindoles in good to excellent yields.
authors.affiliation: Institut Curie, Centre de Recherche, Paris, France.
authors.forename: Géraldine
authors.initials: G
authors.lastname: Calvet
authors.forename: Marion
authors.initials: M
authors.lastname: Livecchi
authors.forename: Frédéric
authors.initials: F
authors.lastname: Schmidt
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry
chemical_list: C512290:5-azaindole; D000480:Alkynes; D001372:Aza Compounds; D007211:Indoles; D011725:Pyridines; D010165:Palladium