title: Atipical Kawasaki disease with coronary aneurysm in infant.
abstract: Kawasaki disease is an acute febrile disease of unknown etiology, characterized by systemic vascular inflammation involving the small and medium sized arteries, with a predilection for the coronary arteries. It represents the leading cause of acquired heart diseases in children in developed countries. Diagnosis, difficult because of the clinical characteristics of the disease with typical signs and symptoms appearing sequentially and not simultaneously, may be even more complicated in case of unusual presentation, leading to delay in recognition, particularly in infant in whom a higher incidence of coronary arteries aneurysms has been reported. A high index of suspicion of Kawasaki disease must be maintained in case of prolonged fever in these patients. Timely appropriate treatment is essential to avoid severe sequels. We report the case of a 2 months old male infant with persistent febrile episode, transferred to us from another institution, who presented on echocardiography giant aneurysms on both coronary arteries.
authors.affiliation: Pediatric Hematology and Oncology Unit, Department of Pediatrics, Parma University Hospital, Italy. idodi@ao.pr.it
authors.forename: Icilio
authors.initials: I
authors.lastname: Dodi
authors.forename: Vera
authors.initials: V
authors.lastname: Raggi
authors.forename: Marta
authors.initials: M
authors.lastname: Verna
authors.forename: Bertrand
authors.initials: B
authors.lastname: Tchana
authors.forename: Daniela
authors.initials: D
authors.lastname: Vignali
authors.forename: Maria Antonietta
authors.initials: MA
authors.lastname: Bandello
authors.forename: Silvia
authors.initials: S
authors.lastname: Lacava
authors.forename: Gian Carlo
authors.initials: GC
authors.lastname: Izzi
authors.forename: Aldo
authors.initials: A
authors.lastname: Agnetti
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D006328:Cardiac Catheterization; D003323:Coronary Aneurysm / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D017023:Coronary Angiography; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004452:Echocardiography; D005500:Follow-Up Studies; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D018084:Ultrasonography, Interventional
chemical_list: D000925:Anticoagulants; D007155:Immunologic Factors