title: [Two-stage revision for treatment of periprosthetic infection following hip arthroplasty].
abstract: OBJECTIVE
  To evaluate the efficacy and optimal re-implantation time of two-stage revision for management of periprosthetic infection following hip arthroplasty.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 15 patients (15 hip joints) undergoing two-stage ipsilateral total hip arthroplasty (THA) revision from January, 2006 to January, 2010. In the first stage, after surgical debridement and thorough removal of all the implants, a self-made Vancomycin-loaded cement spacer was implanted. The second stage operation was performed 3-6 months later for debridement and removal of the antibiotic-loaded spacer, followed by re-implantation of Vancomycin-loaded bone cement prosthesis in 9 cases and cementless prosthesis in 6 cases. The patients were followed up for 9-46 months (mean 25 months) after the operation.
  
  
  RESULTS
  No reinfection or prosthesis loosening/displacement was found in these cases after the operation. The Harris score increased from 40.3 before the operation to 54.0 after the first-stage operation, and to 88.2 at the last follow-up.
  
  
  CONCLUSIONS
  Two-stage revision is effective for treatment of periprosthetic infection following hip arthroplasty, and 3-6 months can be the optimal interval between the two the first-stage and second-stage operation for re-implantation.
authors.affiliation: Ninth Department of Orthopedics, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
authors.forename: Yong-Gen
authors.initials: YG
authors.lastname: Zou
authors.forename: Zong-Quan
authors.initials: ZQ
authors.lastname: Feng
authors.forename: Ji-Si
authors.initials: JS
authors.lastname: Xing
authors.forename: Zhi-Hao
authors.initials: ZH
authors.lastname: Peng
authors.forename: Xuan
authors.initials: X
authors.lastname: Luo
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome