title: Validation of optical low coherence reflectometry retinal and choroidal biometry.
abstract: OBJECTIVE
  To compare measurements of retinal thickness (RT) and choroidal thickness (ChT) obtained with an optical low coherence reflectometry (OLCR) biometer (Lenstar LS 900) with those obtained with a spectral domain optical coherence tomographer (SD OCT) (Copernicus SOCT HR) in young normal subjects.
  
  
  METHODS
  Twenty young adult subjects had foveal RT and subfoveal ChT measurements obtained with OLCR biometry and SD OCT. RT and ChT was derived through manual analysis of A-scan data from the OLCR biometer. An average SD OCT foveal B-scan image derived from a series of 50 multiple B-scans was also analyzed to determine RT and ChT for each subject. Measurements from the two instruments were compared using Pearson correlation and Bland-Altman analysis.
  
  
  RESULTS
  RT and ChT measurements from the two instruments were highly correlated (r of 0.80 and 0.94, respectively, p<0.0001). The mean RT with SD OCT and OLCR were 195 ± 17 μm and 196 ± 16 μm, respectively (mean difference, 1 ± 8 μm). The mean ChT was 324 ± 71 μm and 328 ± 84 μm with SD OCT and OLCR, respectively (mean difference, 4 ± 24 μm).
  
  
  CONCLUSIONS
  Foveal RT and subfoveal ChT measures from OLCR biometry exhibit a strong correlation and good agreement with measures derived from SD OCT in a population of young adult subjects.
authors.affiliation: Contact Lens and Visual Optics Laboratory, School of Optometry, Queensland University of Technology, Kelvin Grove, Brisbane, Queensland, Australia. sa.read@qut.edu.au
authors.forename: Scott A
authors.initials: SA
authors.lastname: Read
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Collins
authors.forename: David
authors.initials: D
authors.lastname: Alonso-Caneiro
mesh_terms: D000328:Adult; D001699:Biometry / Q000379:methods*; D002829:Choroid / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012160:Retina / Q000033:anatomy & histology*; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000592:standards; D055815:Young Adult