title: Exploration on asymmetric synthesis of flavanone catalyzed by (S)-pyrrolidinyl tetrazole.
abstract: An improved method of the synthesis of flavanones catalyzed by pyrrolidine and BF(3) ·Et(2) O has been developed and a lot of flavanones could be easily synthesized via this method. The asymmetric synthesis of flavanone from benzaldehyde and 5-fluoro-2-hydroxyacetophenone has been studied and flavanone with moderate enantioselectivity was obtained in one step.
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, China.
authors.forename: Shubao
authors.initials: S
authors.lastname: Zhou
authors.forename: Yuqiang
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yalan
authors.initials: Y
authors.lastname: Xing
authors.forename: Naixing
authors.initials: N
authors.lastname: Wang
authors.forename: Linghua
authors.initials: L
authors.lastname: Cao
mesh_terms: D002384:Catalysis; D044950:Flavanones / Q000138:chemical synthesis* / Q000737:chemistry; D011759:Pyrrolidines / Q000737:chemistry*; D013237:Stereoisomerism; D013777:Tetrazoles / Q000737:chemistry*
chemical_list: C540256:5-(pyrrolidin-2-yl)tetrazole; D044950:Flavanones; D011759:Pyrrolidines; D013777:Tetrazoles; C028610:flavanone