title: [The morphological characteristic of IgA-nephropathy in age aspect].
abstract: We analyzed data from light microscopy, 87 patients with primary IgA-nephropathy (aged 19 to 65 years) confirmed intravital puncture biopsy of the kidney. The study analyzed the age characteristics of morphological changes and their correlation with age and relationships between them. It is shown that the severity of global and segmental sclerosis does not depend on age of the patient with IgA-nephropathy. It is authentically shown that the severity of sclerotic processes (both segmental and global sclerosis) depends on the morphological changes only in patients aged 31 to 45 years. In this same group we identified the dependence of expression of hypertrophy of arteries and arterioles of kidney tissue from other morphological changes. Thus, the most significant changes according to light microscopy were found in IgA-nephropathy patients aged 31 to 45 years.
authors.forename: A L
authors.initials: AL
authors.lastname: Ar'ev
authors.forename: T S
authors.initials: TS
authors.lastname: Riabova
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001707:Biopsy, Needle; D018450:Disease Progression; D005260:Female; D020022:Genetic Predisposition to Disease; D005920:Glomerular Mesangium / Q000098:blood supply / Q000473:pathology; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology; D006417:Hematuria; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D066298:In Vitro Techniques; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D008859:Microscopy, Polarization; D008875:Middle Aged; D012077:Renal Artery / Q000473:pathology*; D012598:Sclerosis; D012720:Severity of Illness Index
chemical_list: D007070:Immunoglobulin A