title: Micropolygyria in an infant born to a patient with severe anorexia nervosa: a case report.
abstract: We report the case of an anorexia nervosa (AN) patient with extremely low body weight who became pregnant following ovulation induction and subsequently delivered an infant with micropolygyria. To the best of our knowledge, no previous report has described live birth for a patient with such low body weight. The patient underwent hMG-hCG therapy for ovulation induction. Despite becoming pregnant, weight loss continued with extreme anemia occurring during the pregnancy. However, blood transfusion therapy was used for successful treatment. Despite the therapeutic and protective measures instituted, the child was born with micropolygyria. Pregnancy in an AN patient with extremely low body weight needs therapeutic intervention during early pregnancy with aggressive precautionary measures, particularly against anemia. On the basis of our experience, we consider that ovulation induction therapy should not be administered without sufficient caution for an AN patient with low body weight.
authors.affiliation: Department of Psychiatry and Neuroscience, Gunma University Graduate School of Medicine, Gunma, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takei
authors.forename: Masashi
authors.initials: M
authors.lastname: Suda
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Aoyama
authors.forename: Kosuke
authors.initials: K
authors.lastname: Narita
authors.forename: Masaki
authors.initials: M
authors.lastname: Kameyama
authors.forename: Toru
authors.initials: T
authors.lastname: Uehara
authors.forename: Masato
authors.initials: M
authors.lastname: Fukuda
authors.forename: Masahiko
authors.initials: M
authors.lastname: Mikuni
mesh_terms: D000328:Adult; D000740:Anemia / Q000150:complications* / Q000473:pathology; D000856:Anorexia Nervosa / Q000150:complications* / Q000473:pathology; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D054081:Malformations of Cortical Development, Group II / Q000209:etiology* / Q000473:pathology; D039382:Maternal Nutritional Physiological Phenomena; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic