title: Predictors of mortality in surgical patients with Acinetobacter baumannii bacteremia.
abstract: BACKGROUND
  Acinetobacter baumannii has emerged as an important pathogen of nosocomial infection. The aim of this study was to evaluate the predictors of poor outcome in surgical patients with A baumannii bacteremia.
  
  
  METHODS
  We retrospectively recruited a total of 50 patients who developed A baumannii bacteremia within 2 weeks after surgery during a 113-month period. The primary outcome for this study was all-cause 14-day mortality. Clinical and laboratory data, antimicrobial susceptibility, treatment, and Sequential Organ Failure Assessment (SOFA) score were evaluated as possible predictors of outcome.
  
  
  RESULTS
  The 14-day mortality was 20% and there was no association between type of surgery and mortality. The SOFA score was the only independent predictor of 14-day mortality after adjustment for other variables. The calibration was acceptable (Hosmer-Lemeshow χ(2) = 3.65, p = 0.72) and the discrimination was good (area under the receiver operating characteristic curve: 0.80 ± 0.07, 95% confidence interval, 0.67-0.94). We found that a SOFA score ≥ 7 was a significant predictor of 14-day mortality in surgical patients with A baumannii bacteremia.
  
  
  CONCLUSIONS
  The SOFA score assessed at the onset of bacteremia is a reliable tool for predicting 14-day mortality in surgical patients with A baumannii bacteremia.
authors.affiliation: Department of Medicine, National Yang-Ming University Hospital, Yilan, Taiwan.
authors.forename: Su-Jung
authors.initials: SJ
authors.lastname: Chen
authors.forename: Tze-Fan
authors.initials: TF
authors.lastname: Chao
authors.forename: Mei-Chun
authors.initials: MC
authors.lastname: Chiang
authors.forename: Shu-Chen
authors.initials: SC
authors.lastname: Kuo
authors.forename: Liang-Yu
authors.initials: LY
authors.lastname: Chen
authors.forename: Dung-Hung
authors.initials: DH
authors.lastname: Chiang
authors.forename: Ti
authors.initials: T
authors.lastname: Yin
authors.forename: Te-Li
authors.initials: TL
authors.lastname: Chen
authors.forename: Chang-Phone
authors.initials: CP
authors.lastname: Fung
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy / Q000401:mortality* / Q000601:surgery; D040981:Acinetobacter baumannii; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000188:drug therapy / Q000401:mortality* / Q000601:surgery; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome