title: A rapid and efficient synthetic route to terminal arylacetylenes by tetrabutylammonium hydroxide- and methanol-catalyzed cleavage of 4-aryl-2-methyl-3-butyn-2-ols.
abstract: Tetrabutylammonium hydroxide with methanol as an additive was found to be a highly active catalyst for the cleavage of 4-aryl-2-methyl-3-butyn-2-ols. The reaction was performed at 55-75 °C and gave terminal arylacetylenes in good to excellent yields within several minutes. Compared with the usual reaction conditions (normally >110 °C, several hours), this novel catalyst system can dramatically decrease the reaction time under much milder conditions.
authors.affiliation: Department of Polymer Materials and Composites, School of Materials Science and Engineering, Beihang University, Beijing 100191, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Pengcheng
authors.initials: P
authors.lastname: Huang