title: [Biochemical criteria for severity of colonic dysbacteriosis].
abstract: The purpose of the investigation was to estimate the content of malondialdehyde (MDA) in the coprofiltrates of human beings with bacteriologically verified colonic dysbacteriosis and to clarify a relationship of the amount of MDA in the coprofiltrates to the degree of the abnormal qualitative and quantitative composition of microbiocenosis. Specimens from 109 subjects aged 19 to 56 years were examined. The change in the level of MDA in the coprofiltrates was found to correspond to the impairment in the composition of microbiocenosis. The comparison of the coprofiltrate content of MDA with enteric microbiocenotic changes allows one to consider that MDA levels may serve as a biochemical criterion for the degree of dysbacteriosis and be used as an additional method for its diagnosis.
authors.forename: M N
authors.initials: MN
authors.lastname: Gapon
authors.forename: L N
authors.initials: LN
authors.lastname: Ternovskaia
mesh_terms: D000328:Adult; D001431:Bacteriological Techniques; D001644:Bifidobacterium / Q000302:isolation & purification; D003106:Colon / Q000737:chemistry / Q000382:microbiology*; D004755:Enterobacteriaceae / Q000302:isolation & purification; D004925:Escherichia / Q000302:isolation & purification; D006801:Humans; D007413:Intestinal Mucosa / Q000737:chemistry / Q000382:microbiology; D007777:Lactobacillaceae / Q000302:isolation & purification; D008315:Malondialdehyde / Q000032:analysis; D008875:Middle Aged; D011511:Proteus / Q000302:isolation & purification; D013210:Staphylococcus / Q000302:isolation & purification; D055815:Young Adult
chemical_list: D008315:Malondialdehyde