title: Virtual screening against obesity.
abstract: The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.
authors.affiliation: Chemical Screening and PLACEBO, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14/AKH BT 25.3, 1090 Vienna, Austria. pmarkt@cemm.oeaw.ac.at
authors.forename: P
authors.initials: P
authors.lastname: Markt
authors.forename: S
authors.initials: S
authors.lastname: Herdlinger
authors.forename: D
authors.initials: D
authors.lastname: Schuster
mesh_terms: D000818:Animals; D019440:Anti-Obesity Agents / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D015195:Drug Design; D006801:Humans; D008958:Models, Molecular; D009765:Obesity / Q000188:drug therapy*
chemical_list: D019440:Anti-Obesity Agents