title: Treatment of acute hepatitis C virus infection in HIV-infected MSM: the effect of treatment duration.
abstract: We evaluated hepatitis C virus (HCV) treatment and the effect of treatment duration (24 versus 48 weeks) on treatment outcome among 50 HIV-infected men who have sex with men with acute HCV infection in Amsterdam. Overall sustained virological response (SVR) rate was 76%. Treatment duration was not significantly associated with SVR (adjusted odds ratio = 2.32; 95% confidence interval 0.39-13.97), suggesting that 24-week treatment may be sufficient for acute HCV infection in HIV-coinfected patients.
authors.affiliation: Department of Research, Public Health Service of Amsterdam, Cluster of Infectious Diseases, The Netherlands.
authors.forename: Femke A E
authors.initials: FA
authors.lastname: Lambers
authors.forename: Kees
authors.initials: K
authors.lastname: Brinkman
authors.forename: Janke
authors.initials: J
authors.lastname: Schinkel
authors.forename: Ingrid J B
authors.initials: IJ
authors.lastname: Spijkerman
authors.forename: Richard
authors.initials: R
authors.lastname: Molenkamp
authors.forename: Roel A
authors.initials: RA
authors.lastname: Coutinho
authors.forename: Maria
authors.initials: M
authors.lastname: Prins
authors.forename: Jan T M
authors.initials: JT
authors.lastname: van der Meer
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006526:Hepatitis C / Q000188:drug therapy*; D018937:Hepatitis C Antibodies / Q000187:drug effects*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D019562:Viral Load / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D018937:Hepatitis C Antibodies