title: Regioselective semihydrogenation of dienes.
abstract: A one-pot, three-step strategy for the regioselective semihydrogenation of dienes is described. This procedure uses 9-BBN-H as a temporary protective group for alkenes. Yields range from 55% to 95%, and the reaction is tolerant of a variety of common functional groups. Additionally, the final elimination step of the sequence can be replaced with a peroxide-mediated alkylborane oxidation, generating regioselectively semihydrogenated product alcohols.
authors.affiliation: Department of Chemistry, Furman University, 3300 Poinsett Highway, Greenville, South Carolina 29613, United States.
authors.forename: Thomas J A
authors.initials: TJ
authors.lastname: Graham
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Poole
authors.forename: Charles N
authors.initials: CN
authors.lastname: Reese
authors.forename: Brian C
authors.initials: BC
authors.lastname: Goess