title: [Changes of contractile activity of the colon under psychogenic stress before and after blockade of M- and N-cholinergic and beta-adrenoceptors].
abstract: In experiments on conscious rabbits, myoelectric activity (contractile activity index) was recorded in 2 sites of proximal and in 2 sites of distal part of the colon under psychogenic stress induced by firm fastening of the animal to a frame in supine position. Stressor impact caused decrease of the contractile activity in proximal and distal parts of the colon, due to "alpha-adrenergic" (in initial stage of stress reaction) and "nonadrenergic noncholinergic" inhibition. Stress-induced increase of the contractile activity of the colon was limited to the initial segment of its distal part, and was due to centrogenic stimulation of the preganglionic neurons of the parasympathetic nervous system and effector cholinergic neurons of the enteric nervous system.
authors.forename: T P
authors.initials: TP
authors.lastname: Berezina
authors.forename: V I
authors.initials: VI
authors.lastname: Ovsiannikov
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D003106:Colon; D017615:Enteric Nervous System / Q000503:physiopathology*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D008297:Male; D018727:Muscarinic Antagonists / Q000494:pharmacology*; D018733:Nicotinic Antagonists / Q000494:pharmacology*; D011817:Rabbits; D011943:Receptors, Adrenergic, beta; D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic; D013315:Stress, Psychological / Q000503:physiopathology*
chemical_list: D000319:Adrenergic beta-Antagonists; D018727:Muscarinic Antagonists; D018733:Nicotinic Antagonists; D011943:Receptors, Adrenergic, beta; D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic