title: Endovascular abdominal aortic aneurysm repair in women.
abstract: The objective of this review is to establish the role of endovascular aortic aneurysm repair (EVAR) in women. A step by step approach is taken looking at sex and gender differences in epidemiology, pathogenesis and natural history. We then proceed to discuss the results from the three randomized controlled trials comparing EVAR to open repair. Finally, sex-specific secondary prevention, risk factor management and medication, is discussed. Women seem to have higher mortality and more complications after EVAR. Risk factors such as diabetes and hypertension are associated with worse outcome in women compared to men. The role of EVAR in women is poorly investigated and its definite role remains to be determined. Aggressive treatment of risk factors and the optimisation of medication in women are indicated and deserve more attention in clinical practice and future research.
authors.affiliation: Program for the Assessment of Radiological Technology (ART Program), Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
authors.forename: N
authors.initials: N
authors.lastname: Grootenboer
authors.forename: J M
authors.initials: JM
authors.lastname: Hendriks
authors.forename: P W M
authors.initials: PW
authors.lastname: Cuypers
authors.forename: M R H M
authors.initials: MR
authors.lastname: van Sambeek
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000517:prevention & control / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D012307:Risk Factors; D012737:Sex Factors