title: [Investigation on an outbreak of measles caused by new virus (d11 genotype) imported from Myanmar].
abstract: OBJECTIVE
  To study the relevant factors on an measles outbreak caused by imported new virus (d11 genotype) from Myanmar and to develop effective strategies and measures.
  
  
  METHODS
  On-site investigation on the outbreak was carried out.
  
  
  RESULTS
  There were four townships (66%) in Menglian county reported 15 cases of measles, with 7 cases aged 6 months to 5 years old, 2 cases with the history of measles vaccination (MV). Another 8 cases were 21 to 49 year-olds but their histories on immunization were unclear. 14 of the measles cases with Myanmar citizenship came to China for treatment. They were aged 10 months to 13 years old, with only one case had ever received MV vaccination. For all the 29 cases, except for one case who did not adopt the sample case of Myanmar, the remaining 28 patients were positive for measles IgM antibodies. 6 cases of measles virus RNA were detected in the amplified sequence which showed genotype d11, and was considered Myanmar imported wild virus. 184 people received the MV inoculation, with a rate of 61.96% and the serum samples showed a measles IgG antibody positive rate of 87.50%. Manner MV emergency vaccination was carried out timely in that county so the measles outbreak was effectively controlled.
  
  
  CONCLUSIONS
  Imported measles cases from foreign countries might lead to epidemic, indicating the difficulty and challenge in the elimination of measles in our province. Emergent vaccination of MV could interrupt the transmission of the disease. Our experience showed that MV was effective in the prevention of d11 genotypes measles infection in the area.
authors.affiliation: Yunnan Center for Disease Control and Prevention, Kunming 650022, China.
authors.forename: Yan-kun
authors.initials: YK
authors.lastname: Pang
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Li
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Ding
authors.forename: Min
authors.initials: M
authors.lastname: Peng
authors.forename: Yuan-qing
authors.initials: YQ
authors.lastname: Zhu
authors.forename: Zheng-you
authors.initials: ZY
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology* / Q000821:virology*; D008458:Measles Vaccine / Q000008:administration & dosage; D008459:Measles virus / Q000235:genetics*; D008875:Middle Aged; D002052:Myanmar / Q000453:epidemiology; D012367:RNA, Viral / Q000302:isolation & purification; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine; D012367:RNA, Viral