title: Enantioselective sensing of amines based on [1 + 1]-, [2 + 2]-, and [1 + 2]-condensation with fluxional arylacetylene-derived dialdehydes.
abstract: Four induced circular dichroism (ICD) probes exhibiting a stereodynamic arylacetylene framework and terminal aldehyde units have been prepared. The CD silent sensors generate a strong chiroptical response to substrate-controlled induction of axial chirality upon selective [1 + 1]-, [2 + 2]-, and [1 + 2]-condensation. The intense Cotton effects can be exploited for in situ ICD analysis of the absolute configuration and ee of a wide range of amines.
authors.affiliation: Department of Chemistry, Georgetown University, Washington, DC 20057, United States.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Iwaniuk
authors.forename: Christian
authors.initials: C
authors.lastname: Wolf