title: Weight suppression and risk of future increases in body mass: effects of suppressed resting metabolic rate and energy expenditure.
abstract: BACKGROUND
  Weight suppression, which reflects the difference between the highest previous weight and current weight, has predicted future increases in body mass index (BMI) and bulimic pathology; however, the mechanisms underlying these predictive effects are unclear.
  
  
  OBJECTIVE
  The current study sought to test whether weight suppression predicts future increases in BMI and bulimic symptoms and whether suppressed resting metabolic rate (RMR) and suppressed total energy expenditure (TEE) drive these relations.
  
  
  METHODS
  A randomly selected subsample of 91 young women in their first year of college with body image concerns completed an RMR assessment--a doubly labeled water assessment of TEE--and provided data on weight suppression and change in BMI and bulimic symptoms over a 6-mo follow-up period.
  
  
  RESULTS
  Weight suppression predicted future increases in BMI and correlated inversely with suppressed RMR and TEE, yet this predictive effect did not decrease when suppressed RMR and TEE were controlled for. Weight suppression, however, did not predict future increases in bulimic symptoms.
  
  
  CONCLUSIONS
  The results provide additional evidence that weight suppression predicts future increases in BMI but not in bulimic symptoms. Weight suppression showed moderate relations with suppressed RMR and TEE, but these variables do not appear to drive the predictive effect on future increases in BMI. This trial was registered at clinicaltrials.gov as NCT00433680.
authors.affiliation: Oregon Research Institute, Eugene, OR, USA. estice@ori.org
authors.forename: Eric
authors.initials: E
authors.lastname: Stice
authors.forename: Shelley
authors.initials: S
authors.lastname: Durant
authors.forename: Kyle S
authors.initials: KS
authors.lastname: Burger
authors.forename: Dale A
authors.initials: DA
authors.lastname: Schoeller
mesh_terms: D000293:Adolescent; D001481:Basal Metabolism; D015992:Body Mass Index; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D012044:Regression Analysis; D015431:Weight Loss; D055815:Young Adult