title: Listeriosis in human pregnancy: a systematic review.
abstract: Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregnant women are at high risk for listeriosis, but symptoms are non-specific and diagnosis is difficult. The intracellular life-cycle of Listeria protects the bacterium from host innate and adaptive immune responses. Antibiotic treatment requires agents able to penetrate, distribute, and remain stable within host cells. Prolonged use of high-dose ampicillin can significantly improve neonatal outcome.
authors.affiliation: Perinatology Research Branch, NICHD/NIH/DHHS, Wayne State University/Hutzel Women's Hospital, 3990 John R, Detroit, MI 48201, USA. rlamont@med.wayne.edu
authors.forename: Ronald F
authors.initials: RF
authors.lastname: Lamont
authors.forename: Jack
authors.initials: J
authors.lastname: Sobel
authors.forename: Shali
authors.initials: S
authors.lastname: Mazaki-Tovi
authors.forename: Juan Pedro
authors.initials: JP
authors.lastname: Kusanovic
authors.forename: Edi
authors.initials: E
authors.lastname: Vaisbuch
authors.forename: Sun Kwon
authors.initials: SK
authors.lastname: Kim
authors.forename: Niels
authors.initials: N
authors.lastname: Uldbjerg
authors.forename: Roberto
authors.initials: R
authors.lastname: Romero
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005516:Food Microbiology; D005517:Foodborne Diseases / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008089:Listeria monocytogenes / Q000254:growth & development; D008088:Listeriosis / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D012307:Risk Factors; D012621:Seasons
chemical_list: D000900:Anti-Bacterial Agents