title: [The current status of nausea, vomiting and food intake in outpatients with cancer chemotherapy].
abstract: A survey on chemotherapy-induced nausea, vomiting and food intake was conducted on 126 outpatients receiving chemotherapy during a days from February 1 to February 12, 2010 in our hospital. Responses were obtained from 66 outpatients. In the acute phase, 11%of the patients developed nausea. In the late phase, 35%patients developed nausea. The development of nausea was significantly increased in the late phase, compared to the acute phase(p=0. 0008). Though nobody developed vomiting in the acute phase, 3% of the patients developed vomiting in the late phase. For food intake, in the acute phase, nobody showed a"reduced amount of diet", and 12% showed"not eating". In the late phase, 26% of the patients showed"reduced amount of food", and 8%"not eating". Food intake was significantly decreased in the late phase, compared in acute phase(p=0. 0001). Currently, in our hospital, steroids and/or 5-HT3 antagonists are given for antiemetic therapy, but the effect is not enough. We should add other antiemetics, which act in the late phase.
authors.affiliation: Dept. of Respiratory Medicine, Ishikawa Prefectural Central Hospital, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Nishi
authors.forename: Koji
authors.initials: K
authors.lastname: Kurokawa
authors.forename: Jyosuke
authors.initials: J
authors.lastname: Hara
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Demura
authors.forename: Naomi
authors.initials: N
authors.lastname: Fujikawa
authors.forename: Yukari
authors.initials: Y
authors.lastname: Nikko
authors.forename: Sumie
authors.initials: S
authors.lastname: Yoshizaki
authors.forename: Chiyoko
authors.initials: C
authors.lastname: Yamada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001069:Appetite Regulation / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced*; D009369:Neoplasms / Q000188:drug therapy*; D010045:Outpatients; D011795:Surveys and Questionnaires; D014839:Vomiting / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents