title: Seasonal and 2009 pandemic influenza A (H1N1) virus infection during pregnancy: a population-based study of hospitalized cases.
abstract: We sought to describe characteristics of hospitalized reproductive-aged (15-44 years) women with seasonal (2005/2006 through 2008/2009) and 2009 pandemic influenza A (H1N1) virus infection. We used population-based data from the Emerging Infections Program in 10 US states, and compared characteristics of pregnant (n = 150) and nonpregnant (n = 489) seasonal, and pregnant (n = 489) and nonpregnant (n = 1088) pandemic influenza cases using χ(2) and Fisher's exact tests. Pregnant women represented 23.5% and 31.0% of all reproductive-aged women hospitalized for seasonal and pandemic influenza, respectively. Significantly more nonpregnant than pregnant women with seasonal (71.2% vs 36.0%) and pandemic (69.7% vs 31.9%) influenza had an underlying medical condition other than pregnancy. Antiviral treatment was significantly more common with pandemic than seasonal influenza for both pregnant (86.5% vs 24.0%) and nonpregnant (82.0% vs 55.2%) women. Pregnant women comprised a significant proportion of influenza-hospitalized reproductive-aged women, underscoring the importance of influenza vaccination during pregnancy.
authors.affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA. acreanga@cdc.gov
authors.forename: Andreea A
authors.initials: AA
authors.lastname: Creanga
authors.forename: Laurie
authors.initials: L
authors.lastname: Kamimoto
authors.forename: Kimberly
authors.initials: K
authors.lastname: Newsome
authors.forename: Tiffany
authors.initials: T
authors.lastname: D'Mello
authors.forename: Denise J
authors.initials: DJ
authors.lastname: Jamieson
authors.forename: Marianne E
authors.initials: ME
authors.lastname: Zotti
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Arnold
authors.forename: Joan
authors.initials: J
authors.lastname: Baumbach
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Bennett
authors.forename: Monica M
authors.initials: MM
authors.lastname: Farley
authors.forename: Ken
authors.initials: K
authors.lastname: Gershman
authors.forename: David
authors.initials: D
authors.lastname: Kirschke
authors.forename: Ruth
authors.initials: R
authors.lastname: Lynfield
authors.forename: James
authors.initials: J
authors.lastname: Meek
authors.forename: Craig
authors.initials: C
authors.lastname: Morin
authors.forename: Arthur
authors.initials: A
authors.lastname: Reingold
authors.forename: Patricia
authors.initials: P
authors.lastname: Ryan
authors.forename: William
authors.initials: W
authors.lastname: Schaffner
authors.forename: Ann
authors.initials: A
authors.lastname: Thomas
authors.forename: Shelley
authors.initials: S
authors.lastname: Zansky
authors.forename: Lyn
authors.initials: L
authors.lastname: Finelli
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Honein
mesh_terms: D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D015897:Comorbidity; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000188:drug therapy / Q000453:epidemiology*; D058873:Pandemics; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology*; D012621:Seasons; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000998:Antiviral Agents