title: Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60).
abstract: Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries. This is the first report of a fatal meningitis case caused by a cc60 clonal complex meningococcus in Brazil. Despite the immune-compromised state of the patient, the fatal outcome here described shows the potential pathogenic behavior of strains belonging to this clonal complex and how compromised hosts can be susceptible to meningococcal infections even if the strain is not particularly invasive.
authors.affiliation: Controle de Qualidade em Saude, Fundacao Oswaldo Cruz, Av. Brasil 4365, Rio de Janeiro, Brazil.
authors.forename: Claudia Ferreira de
authors.initials: CF
authors.lastname: Andrade
authors.forename: Denise Cotrim da
authors.initials: DC
authors.lastname: Cunha
authors.forename: Veronica
authors.initials: V
authors.lastname: Cavalcanti
authors.forename: Ivano de
authors.initials: Id
authors.lastname: Filippis
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D004269:DNA, Bacterial / Q000032:analysis*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000382:microbiology*; D038542:Neisseria meningitidis, Serogroup C / Q000235:genetics*; D012703:Serotyping
chemical_list: D004269:DNA, Bacterial