title: Tumour-like presentations of anogenital herpes simplex in HIV-positive patients.
abstract: Genital and perianal ulcers seen in patients with HIV are commonly due to herpes simplex virus (HSV) infection. While it is well known that the characteristic presentation of HSV is a vesicular rash or crops of erosions, the clinical presentation of genital HSV infection in HIV is varied and can assume vegetative, hypertrophic, condyloma-like, nodular, ulcerative and tumour-like nodules or plaques. These unusual presentations often lead to a delayed diagnosis. We describe five immunocompromised HIV-positive patients with CD4 counts ranging from 114 to 326 cells/μL with unusual presentations of anogenital herpes.
authors.affiliation: National Skin Center, Singapore, Singapore. Harneet.ranu@gmail.com
authors.forename: H
authors.initials: H
authors.lastname: Ranu
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Chio
authors.forename: P
authors.initials: P
authors.lastname: Sen
mesh_terms: D000328:Adult; D001004:Anus Diseases / Q000150:complications / Q000473:pathology* / Q000821:virology; D001005:Anus Neoplasms / Q000150:complications / Q000473:pathology* / Q000821:virology; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications / Q000473:pathology* / Q000821:virology; D005834:Genital Neoplasms, Male / Q000150:complications / Q000473:pathology* / Q000821:virology; D015658:HIV Infections / Q000150:complications* / Q000821:virology; D015497:HIV-1; D006558:Herpes Genitalis / Q000150:complications / Q000473:pathology* / Q000821:virology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D018139:Simplexvirus / Q000472:pathogenicity