title: Lewis acid organocatalysts.
abstract: Abstract The term Lewis acid catalysts generally refers to metal salts like aluminium chloride, titanium chloride and zinc chloride. Their application in asymmetric catalysis can be achieved by the addition of enantiopure ligands to these salts. However, not only metal centers can function as Lewis acids. Compounds containing carbenium, silyl or phosphonium cations display Lewis acid catalytic activity. In addition, hypervalent compounds based on phosphorus and silicon, inherit Lewis acidity. Furthermore, ionic liquids, organic salts with a melting point below 100 degrees C, have revealed the ability to catalyze a range of reactions either in substoichiometric amount or, if used as the reaction medium, in stoichiometric or even larger quantities. The ionic liquids can often be efficiently recovered. The catalytic activity of the ionic liquid is explained by the Lewis acidic nature of their cations. This review covers the survey of known classes of metal-free Lewis acids and their application in catalysis.
authors.affiliation: Clausthal University of Technology, Leibnizstr. 6, 38678 Clausthal-Zellerfeld, Germany.
authors.forename: Oksana
authors.initials: O
authors.lastname: Sereda
authors.forename: Sobia
authors.initials: S
authors.lastname: Tabassum
authors.forename: René
authors.initials: R
authors.lastname: Wilhelm
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D052578:Ionic Liquids / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D058116:Lewis Acids / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D052578:Ionic Liquids; D007659:Ketones; D058116:Lewis Acids; D009943:Organophosphorus Compounds; D017646:Organosilicon Compounds