title: Skeletal recovery from hepatitis C-associated osteosclerosis (HCAO) following antiviral treatment.
abstract: Hepatitis C-associated osteosclerosis (HCAO) is characterized by increased bone mass following hepatitis C infection. We report here a case of HCAO that lasted 8 years before the patient received antiviral hepatitis treatment. Seven years after the antiviral treatment, the evolution of radiographs and densitometry showed skeletal recovery of osteosclerosis. This case strengthens the relationship between viral infection and osteosclerosis.
authors.affiliation: Rheumatology Unit, Department of Rheumatology, hôpital de Hautepierre, University Hospital, 67000 Strasbourg, France. Rose-marie.Javier@chru-strasbourg.fr
authors.forename: Rose-Marie
authors.initials: RM
authors.lastname: Javier
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: de Vernejoul
authors.forename: Naji
authors.initials: N
authors.lastname: Afif
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Kuntz
authors.forename: Jean
authors.initials: J
authors.lastname: Sibilia
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008875:Middle Aged; D010026:Osteosclerosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D011859:Radiography; D020127:Recovery of Function; D012254:Ribavirin / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D012254:Ribavirin; D007372:Interferons