title: The genetics of colored sequence synesthesia: suggestive evidence of linkage to 16q and genetic heterogeneity for the condition.
abstract: Synesthesia is a perceptual condition in which sensory stimulation triggers anomalous sensory experiences. In colored sequence synesthesia (CSS), color experiences are triggered by sequences such as letters or numbers. We performed a family based linkage analysis to identify genetic loci responsible for the increased neural crosstalk underlying CSS. Our results implicate a 23 MB region at 16q12.2-23.1, providing the first step in understanding the molecular basis of CSS.
authors.affiliation: Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Steffie N
authors.initials: SN
authors.lastname: Tomson
authors.forename: Nili
authors.initials: N
authors.lastname: Avidan
authors.forename: Kwanghyuk
authors.initials: K
authors.lastname: Lee
authors.forename: Anand K
authors.initials: AK
authors.lastname: Sarma
authors.forename: Rejnal
authors.initials: R
authors.lastname: Tushe
authors.forename: Dianna M
authors.initials: DM
authors.lastname: Milewicz
authors.forename: Molly
authors.initials: M
authors.lastname: Bray
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Leal
authors.forename: David M
authors.initials: DM
authors.lastname: Eagleman
mesh_terms: D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D003118:Color Perception / Q000235:genetics*; D005260:Female; D018740:Genetic Heterogeneity; D008040:Genetic Linkage / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D010375:Pedigree; D010468:Perceptual Disorders / Q000235:genetics*; D010775:Photic Stimulation / Q000379:methods