title: [Skin resorptive effect of petroleum on some biochemical and immunological parameters in experimental animals].
abstract: Petroleum and its transformation products accumulated in soil along multiple trophic chains enter the human body, which increases the risk of environmentally induced diseases. A thirty-day experiment studied the cutaneous effect of different doses (4250, 850, and 425 mg/kg) of sunflower oil-emulsified petroleum. Its sensitizing and allergic effects were studied on albino guinea pigs. The activity of N-acetyl-beta-D-glucosaminidase and catalase was determined in the sera of non-inbred male albino rats. Petroleum given in a dose of 4250 mg/kg was found to have a negative effect. When its bioeffect occurred, a protective adaptive response of the body revealed in early stages gave way to tension of its adaptive capacities.
authors.forename: N V
authors.initials: NV
authors.lastname: Rusakov
authors.forename: I A
authors.initials: IA
authors.lastname: Kriatov
authors.forename: Z I
authors.initials: ZI
authors.lastname: Koganova
authors.forename: O N
authors.initials: ON
authors.lastname: Mislavskiĭ
authors.forename: I S
authors.initials: IS
authors.lastname: Evseeva
authors.forename: O V
authors.initials: OV
authors.lastname: Ushakova
mesh_terms: D000118:Acetylglucosaminidase / Q000097:blood; D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D002374:Catalase / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004785:Environmental Pollutants / Q000633:toxicity*; D025461:Feedback, Physiological / Q000187:drug effects; D006168:Guinea Pigs; D006967:Hypersensitivity / Q000097:blood / Q000201:enzymology*; D008297:Male; D010578:Petroleum / Q000633:toxicity*; D051381:Rats; D012867:Skin / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology
chemical_list: D004785:Environmental Pollutants; D010578:Petroleum; D002374:Catalase; D000118:Acetylglucosaminidase