title: Effectiveness of rotavirus vaccination in Spain.
abstract: With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network (ReGALIP-www.regalip.org) that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain.
authors.affiliation: Área de Pediatría, Hospital Clínico Universitario de Santiago de Compostela, Spain. federico.martinon.torres@sergas.es
authors.forename: Federico
authors.initials: F
authors.lastname: Martinón-Torres
authors.forename: Marta
authors.initials: M
authors.lastname: Bouzón Alejandro
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Redondo Collazo
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Sánchez Lastres
authors.forename: Sonia
authors.initials: S
authors.lastname: Pértega Díaz
authors.forename: Ma Teresa
authors.initials: MT
authors.lastname: Seoane Pillado
authors.forename: José María
authors.initials: JM
authors.lastname: Martinón Sánchez
mesh_terms: D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012401:Rotavirus / Q000276:immunology; D012400:Rotavirus Infections / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage / Q000276:immunology; D013030:Spain; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D022243:Rotavirus Vaccines