title: Autosome STRs in native South America-Testing models of association with geography and language.
abstract: Information on one Ecuadorian and three Peruvian Amerindian populations for 11 autosomal short tandem repeat (STR) loci is presented and incorporated in analyses that includes 26 other Native groups spread all over South America. Although in comparison with other studies we used a reduced number of markers, the number of populations included in our analyses is currently unmatched by any genome-wide dataset. The genetic polymorphisms indicate a clear division of the populations into three broad geographical areas: Andes, Amazonia, and the Southeast, which includes the Chaco and southern Brazil. The data also show good agreement with proposed hypotheses of splitting and dispersion of major language groups over the last 3,000 years. Therefore, relevant aspects of Native American history can be traced using as few as 11 STR autosomal markers coupled with a broad geographic distribution of sampled populations.
authors.affiliation: Departamento de Genética, Programa de Pós-Graduação em Genética e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. sidia.jacques@ufrgs.br
authors.forename: Sidia M
authors.initials: SM
authors.lastname: Callegari-Jacques
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Tarazona-Santos
authors.forename: Robert H
authors.initials: RH
authors.lastname: Gilman
authors.forename: Phabiola
authors.initials: P
authors.lastname: Herrera
authors.forename: Lilia
authors.initials: L
authors.lastname: Cabrera
authors.forename: Sidney E B
authors.initials: SE
authors.lastname: dos Santos
authors.forename: Luiza
authors.initials: L
authors.lastname: Morés
authors.forename: Mara H
authors.initials: MH
authors.lastname: Hutz
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Salzano
mesh_terms: D000704:Analysis of Variance; D016000:Cluster Analysis; D019143:Evolution, Molecular; D005787:Gene Frequency; D005828:Genetics, Population; D005843:Geography; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D007802:Language; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D008957:Models, Genetic; D013020:South America