title: Intrastromal injection of antibiotic agent in the management of recalcitrant bacterial keratitis.
abstract: Intrastromal injection is a novel method of delivering an antibiotic agent directly to the site of keratitis. Although intrastromal antifungal agents have been used to manage refractory fungal keratitis, the experience with intrastromal antibiotic agents for bacterial keratitis is more limited. We report a case of refractory bacterial keratitis treated with an intrastromal antibiotic agent and discuss the potential for the clinical use of this modality.
authors.affiliation: City Eye Centre, Brisbane, Australia.
authors.forename: Steve Y-W
authors.initials: SY
authors.lastname: Liang
authors.forename: Graham A
authors.initials: GA
authors.lastname: Lee
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D003319:Corneal Stroma / Q000187:drug effects* / Q000382:microbiology / Q000473:pathology; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D056965:Injections, Intraocular; D019654:Lens Implantation, Intraocular; D008297:Male; D018918:Phacoemulsification; D012008:Recurrence; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D014031:Tobramycin / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D014031:Tobramycin