title: [Incidence of central line-associated bloodstream infection in an intensive care unit].
abstract: BACKGROUND
  Central line-associated bloodstream infection (CLABSI) is one of the most common nosocomial infections. The incidence is higher in paediatric patients than in adults, especially in those admitted to Intensive Care Units (ICU). CLABSI-related morbidity makes it a major health problem; therefore it is necessary to develop prevention strategies against it.
  
  
  METHODS
  An intervention study in a paediatric ICU (PICU) was performed, in order to assess the impact of the introduction of the program «Bacteraemia zero» in December 2007. This program aims to prevent CLABSI. Demographic data and variables related to hospitalisation and infection were collected from January to December 2007 (before the intervention) and from January to December 2008 (after the intervention), and were compared. In the first period, 497 patients were studied, and 495 in the second.
  
  
  RESULTS
  A reduction of 30.4% in the incidence of CLABSI (P=0.49) in the second year was observed (5.5 to 3.8 episodes per 1000 catheter-days). The CVC use ratio was 0.59 and 0.64, respectively. The most frequently isolated organism was coagulase-negative Staphylococcus spp.
  
  
  CONCLUSIONS
  The implementation of a «no bacteraemia» program, involving all staff in the PICU as well as the professionals in infection control, reduces the incidence of CLABSI.
authors.affiliation: Unitat de Patologia Infecciosa i Immunodeficiències de Pediatria, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, España. mespiau@vhebron.net
authors.forename: M
authors.initials: M
authors.lastname: Espiau
authors.forename: M
authors.initials: M
authors.lastname: Pujol
authors.forename: M
authors.initials: M
authors.lastname: Campins-Martí
authors.forename: A M
authors.initials: AM
authors.lastname: Planes
authors.forename: Y
authors.initials: Y
authors.lastname: Peña
authors.forename: J
authors.initials: J
authors.lastname: Balcells
authors.forename: J
authors.initials: J
authors.lastname: Roqueta
mesh_terms: D055499:Catheter-Related Infections / Q000453:epidemiology* / Q000517:prevention & control; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D003428:Cross Infection / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D015278:Intensive Care Units, Pediatric