title: Fluorescent sensing of triphosphate nucleotides via anthracene derivatives.
abstract: A nucleotide is composed of a nucleobase, a five-carbon sugar, and phosphate groups. Recognition of these three sites can provide useful information for the development of selective fluorescent receptors for a specific nucleotide. In this paper, anthracene derivatives with two imidazolium groups at the 1,8- and 9,10-positions, quaternary ammonium groups, or the boronic acid group were examined for the recognition of nucleotides, such as ATP, GTP, CTP, TTP, UTP, ADP, and AMP, via fluorescence changes. The anthracene group provides the interaction between the bases of the nucleotides. The imidazolium and quaternary ammonium groups induce hydrogen bonding interactions with the phosphate groups of the nucleotides. The boronic acid group can interact with the ribose of the nucleotides.
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Ha Na
authors.initials: HN
authors.lastname: Kim
authors.forename: Jong Hun
authors.initials: JH
authors.lastname: Moon
authors.forename: Sook Kyung
authors.initials: SK
authors.lastname: Kim
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Kwon
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Jang
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon
mesh_terms: D000873:Anthracenes / Q000138:chemical synthesis / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006860:Hydrogen Bonding; D007093:Imidazoles / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D009711:Nucleotides / Q000032:analysis* / Q000737:chemistry*; D011122:Polyphosphates / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry
chemical_list: D000873:Anthracenes; D005456:Fluorescent Dyes; D007093:Imidazoles; D009711:Nucleotides; D011122:Polyphosphates; D000644:Quaternary Ammonium Compounds; C029899:imidazole; C034020:anthracene; C005692:triphosphoric acid