title: Imaging changes after stereotactic body radiation therapy for lung and liver tumors.
abstract: Stereotactic body radiation therapy (SBRT) is gaining wide acceptance as a treatment modality for lung and liver tumors, and it is crucial to make an accurate evaluation of the local effects of ablative doses of radiation in terms of local tumor control and normal tissue reaction or damage. The very complex radiation dose distribution of SBRT, the use of a large number of non-opposing and noncoplanar beams, and the delivery of individual ablative doses of radiation may cause substantially different radiographic appearance on diagnostic imaging compared with conventional radiation therapy. Different patterns of radiographic changes have been observed in the lung and liver after SBRT. This article reviews the post-SBRT imaging changes in the lung and liver. Since computed tomography and PET are the most commonly used diagnostic imaging tools for monitoring lung tumor and computed tomography for liver tumors, this article will focus on the changes observed on those imaging modalities.
authors.affiliation: Department of Radiation Oncology, University Hospitals Case Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Lerner Tower B181, Cleveland, OH 44106, USA. simon.lo@UHhospitals.org
authors.forename: Simon S
authors.initials: SS
authors.lastname: Lo
authors.forename: Bin S
authors.initials: BS
authors.lastname: Teh
authors.forename: Jian Z
authors.initials: JZ
authors.lastname: Wang
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Huang
authors.forename: Jennifer
authors.initials: J
authors.lastname: Zook
authors.forename: Tracy
authors.initials: T
authors.lastname: Price
authors.forename: Nina A
authors.initials: NA
authors.lastname: Mayr
authors.forename: John C
authors.initials: JC
authors.lastname: Grecula
authors.forename: Robert D
authors.initials: RD
authors.lastname: Timmerman
authors.forename: Higinia R
authors.initials: HR
authors.lastname: Cardenes
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000601:surgery*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000601:surgery*; D016634:Radiosurgery / Q000379:methods