title: Uterine papillary serous carcinoma.
abstract: Uterine papillary serous carcinoma (UPSC) is a histologic variant of endometrial cancer that accounts for only 10% of new cases of uterine cancer but is responsible for 40% of deaths from the disease. UPSC is an aggressive tumor with a predilection for early spread beyond the uterus. Treatment for UPSC typically entails surgery and in most women is followed by multimodality adjuvant therapy. In this review, we describe the epidemiology, natural history, treatment, and outcome of UPSC.
authors.affiliation: Department of Gynecologic Oncology, University of Oklahoma, Oklahoma City, Oklahoma, USA. kathleenmoore@ouhsc.edu
authors.forename: Kathleen N
authors.initials: KN
authors.lastname: Moore
authors.forename: Amanda Nickles
authors.initials: AN
authors.lastname: Fader
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant