title: (5S)-3-Chloro-5-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]-4-(4-methyl-piperidin-1-yl)furan-2(5H)-one.
abstract: The title compound, C(20)H(32)ClNO(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of (5S)-3,4-dichloro-5-(l-menth-yloxy)furan-2(5H)-one and 4-methyl-piperidine in the presence of potassium fluoride. The furan-one ring is approximately planar [maximum atomic deviation = 0.022 (2) Å] while the cyclo-hexane ring adopts a chair conformation. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Wang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Fu
authors.forename: Song-Liang
authors.initials: SL
authors.lastname: Cai
authors.forename: Zhao-Yang
authors.initials: ZY
authors.lastname: Wang