title: Transoral CO2 laser management for selected supraglottic tumors and neck dissection.
abstract: This study aimed to evaluate transoral laser resection as a method of choice for conservation surgery for supraglottic laryngeal carcinoma in carefully selected patients. Between 1987 and 2006, 55 patients with early supraglottic carcinoma were selected for transoral laser surgery. The outcome of the endoscopic CO(2) laser resection and larynx-sparing functional results without tracheotomy was evaluated. Fifty-five patients with T1, T2 supraglottic carcinomas underwent transoral CO(2) laser resection and seven patients with manifest neck metastasis required a neck dissection at one session with additional postoperative radiation therapy. There was no need for tracheotomy; deglutition was moderately disturbed. Forty of the 55 (73%) patients had no signs of recurrence to date. Fifteen patients with local recurrences underwent salvage therapies: six repeated laser excisions, three radiotherapies, four supraglottic laryngectomies and two total laryngectomies. Laser-specific survival is 84% and larynx preservation is 96%. The overall 5-year-survival after salvage treatment is 98%. Development of late metastasis required five radical neck dissections (RND) and radiation therapy. The results indicated that transoral laser resection can control early supraglottic cancer in selected patients and can be combined with simultaneous neck dissection with less morbidity than "open surgery".
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Tisza Lajos krt. 111, 6725, Szeged, Hungary. mcsanady@freemail.hu.
authors.forename: Miklós
authors.initials: M
authors.lastname: Csanády
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Tisza Lajos krt. 111, 6725, Szeged, Hungary.
authors.forename: Jenő
authors.initials: J
authors.lastname: Czigner
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Tisza Lajos krt. 111, 6725, Szeged, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Vass
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Tisza Lajos krt. 111, 6725, Szeged, Hungary.
authors.forename: József
authors.initials: J
authors.lastname: Jóri
mesh_terms: D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery*; D053685:Laser Therapy / Q000379:methods*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008198:Lymph Nodes / Q000601:surgery*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009055:Mouth; D009333:Neck; D037981:Neck Dissection / Q000379:methods*; D009367:Neoplasm Staging; D012189:Retrospective Studies; D059525:Supraglottitis; D016896:Treatment Outcome