title: Recurrent AA amyloidosis in a kidney transplant.
abstract: Recurrent AA amyloidosis in a kidney transplant is rare, especially when the underlying inflammatory condition is controlled. We present a 59-year-old man who underwent a living donor kidney transplant 17 years ago for kidney failure due to AA amyloid nephropathy in the setting of long-standing Crohn disease. His Crohn disease was quiescent before and after the kidney transplant. Transplant function had been stable until a month before presentation, when he developed worsening proteinuria and decreased kidney function. A transplant biopsy showed recurrent AA amyloidosis despite excellent clinical and histologic control of Crohn disease.
authors.affiliation: Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sethi
authors.forename: Mireille
authors.initials: M
authors.lastname: El Ters
authors.forename: Srividya
authors.initials: S
authors.lastname: Vootukuru
authors.forename: Qi
authors.initials: Q
authors.lastname: Qian
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology*; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012008:Recurrence