title: Terpenoids from Tripterygium wilfordii.
abstract: An abietane diterpenoid, triptobenzene Y and six sesquiterpene polyol esters, wilforsinines C-H, together with 14 known compounds, have been isolated from the roots of Tripterygium wilfordii. The structures of the compounds were elucidated on the basis of spectroscopic analyses. The quinone reductase (QR) induction assay indicated that two compounds showed moderate QR-inducing activities at concentrations of 25 μM and 50 μM, respectively.
authors.affiliation: School of Pharmaceutical Sciences, Zhejiang University, Zijingang Campus, No. 866 Yuhangtang Rd, Hangzhou 310058, China.
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Xu
authors.forename: Juan
authors.initials: J
authors.lastname: Lu
authors.forename: Fang
authors.initials: F
authors.lastname: Sun
authors.forename: Huanzhang
authors.initials: H
authors.lastname: Zhu
authors.forename: Lijun
authors.initials: L
authors.lastname: Wang
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhongjun
authors.initials: Z
authors.lastname: Ma
mesh_terms: D045784:Abietanes / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D045744:Cell Line, Tumor; D002470:Cell Survival; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry* / Q000201:enzymology; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D029757:Tripterygium / Q000737:chemistry* / Q000201:enzymology
chemical_list: D045784:Abietanes; D012717:Sesquiterpenes; C562001:triptobenzene Y; C562000:wilforsinine; D016660:NAD(P)H Dehydrogenase (Quinone)