title: Incremental value of CT venography combined with pulmonary CT angiography for the detection of thromboembolic disease: systematic review and meta-analysis.
abstract: OBJECTIVE
  The objective of our study was to assess the incremental role of CT venography (CTV) combined with pulmonary CT angiography (CTA) in detecting venous thromboembolic disease with a systematic review and meta-analysis of the literature.
  
  
  METHODS
  MEDLINE, Embase, and Web of Science were searched for relevant original articles published from January 1, 1995, to December 31, 2009. A random-effects model was used to obtain the incremental value of CTV in detecting thromboembolic disease.
  
  
  RESULTS
  Twenty-four studies, which included 17,373 patients, met our inclusion criteria. A meta-analysis showed that CTV increased detection rates of venous thromboembolic disease by identifying an additional 3% of cases (95% CI, 2-4%) of isolated deep venous thrombosis (DVT). A subgroup analysis of a high-risk group did not show any difference in the detection of isolated DVT.
  
  
  CONCLUSIONS
  The addition of CTV results in the increased detection of thromboembolic disease. CTV combined with pulmonary CTA has a promising role as a quick and efficient test for venous thromboembolism.
authors.affiliation: Radiology Academy, Leeds Teaching Hospital NHS Trust, Yorkshire, United Kingdom. sonalkrishan11@gmail.com
authors.forename: Sonal
authors.initials: S
authors.lastname: Krishan
authors.forename: Nalinda
authors.initials: N
authors.lastname: Panditaratne
authors.forename: Nalinda
authors.initials: N
authors.lastname: Pandiratne
authors.forename: Rajeev
authors.initials: R
authors.lastname: Verma
authors.forename: Roderick
authors.initials: R
authors.lastname: Robertson
mesh_terms: D000792:Angiography; D006801:Humans; D010690:Phlebography; D011237:Predictive Value of Tests; D013923:Thromboembolism / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed