title: Influence of nutritional status and VO2max on adiponectin levels in men older than 35 years. [corrected].
abstract: BACKGROUND
  Adiponectin is considered an important factor in the pathogenesis of cardiovascular and metabolic diseases, due to its anti- atherogenic and anti-inflammatory properties. Few studies, however, have suggested the existence of a direct association between adiponectin levels and cardiorespiratory fitness and physical activity levels.
  
  
  OBJECTIVE
  To verify the influence of the nutritional status and cardiorespiratory fitness on plasma adiponectin levels in adult men.
  
  
  METHODS
  A total of 250 subjects, all in active duty in the Brazilian Army (BA), with a mean age of 42,6 ± 4,8 years volunteered to participate in the study. Plasma levels of adiponectin were measured, as well as body mass, height, waist circumference (WC), fat percentage by hydrostatic weighing and VO(2max) by ergospirometry. A questionnaire was used to obtain the characteristics of the physical training performed by the individuals.
  
  
  RESULTS
  The sample showed that 121 (48%) individuals were overweight and 36 (14%) were obese. Moreover, 66 individuals (27%) had a body fat percentage > 25% and 26,7% had a WC > 94 cm. Overweight and obese individuals had significantly lower adiponectin levels than those with an adequate nutritional status. Individuals at the highest tertile of VO(2max) had higher adiponectin levels than the others. The adiponectin levels were positively correlated with the total weekly physical training time and VO(2max) and inversely correlated with body mass, BMI and WC. The correlation between adiponectin levels and VO(2max) did not remain significant after being adjusted for BMI and WC.
  
  
  CONCLUSIONS
  Individuals with better cardiorespiratory fitness and normal nutritional status seem to present healthier levels of adiponectin.
authors.affiliation: Escola Nacional de Saúde Pública, Universidade Federal Fluminense, Rio de Janeiro, RJ - Brazil. eduardocmartinez@gmail.com
authors.forename: Eduardo Camillo
authors.initials: EC
authors.lastname: Martinez
authors.forename: Macos de Sá Rego
authors.initials: Mde S
authors.lastname: Fortes
authors.forename: Luiz Antônio dos
authors.initials: LA
authors.lastname: Anjos
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000273:Adipose Tissue / Q000502:physiology; D000328:Adult; D015992:Body Mass Index; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009752:Nutritional Status / Q000502:physiology*; D009765:Obesity / Q000453:epidemiology; D010101:Oxygen Consumption / Q000502:physiology*; D010809:Physical Fitness / Q000502:physiology*; D055105:Waist Circumference / Q000502:physiology*
chemical_list: D052242:Adiponectin