title: The contribution of transcriptomic and proteomic analysis in elucidating stress adaptation responses of Listeria monocytogenes.
abstract: The foodborne transmission of Listeria monocytogenes requires physiological adaptation to various conditions, including the cold, osmotic, heat, acid, alkaline, and oxidative stresses, associated with food hygiene, processing, and preservation measures. We review the current knowledge on the molecular stress adaptation responses in L. monocytogenes cells as revealed through transcriptome, proteome, genetic, and physiological analysis. The adaptation of L. monocytogenes to stress exposure is achieved through global expression changes in a large number of cellular components. In addition, the cross-protection of L. monocytogenes exposed to different stress environments might be conferred through various cellular machineries that seem to be commonly activated by the different stresses. To assist in designing L. monocytogenes mitigation strategies for ready-to-eat food products, further experiments are warranted to specifically evaluate the effects of food composition, additives, preservatives, and processing technologies on the modulation of L. monocytogenes cellular components in response to specific stresses.
authors.affiliation: Department of Food Science, Nutrition and Health Promotion, Mississippi State University, Mississippi State, Mississippi 39762, USA.
authors.forename: Kamlesh A
authors.initials: KA
authors.lastname: Soni
authors.forename: Ramakrishna
authors.initials: R
authors.lastname: Nannapaneni
authors.forename: Taurai
authors.initials: T
authors.lastname: Tasara
mesh_terms: D000222:Adaptation, Physiological; D003086:Bacteriocin Plasmids; D005517:Foodborne Diseases / Q000382:microbiology / Q000517:prevention & control; D020869:Gene Expression Profiling; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008089:Listeria monocytogenes / Q000235:genetics / Q000502:physiology*; D008088:Listeriosis; D009994:Osmolar Concentration; D018384:Oxidative Stress; D040901:Proteomics; D013312:Stress, Physiological / Q000235:genetics* / Q000502:physiology*