title: Three-band decomposition analysis of wall shear stress in pulsatile flows.
abstract: Space-time patterns of wall shear stress (WSS) resulting from the numerical simulation of pulsating hemodynamic flows in semicoronal domains are analyzed, in the case of both regular semicoronal domains and semicoronal domains with bumpy insertions, mimicking aneurysm-like geometries. A new family of cardiovascular risk indicators, which we name three-band diagrams (TBDs), are introduced, as a sensible generalization of the two standard indicators, i.e., the time-averaged WSS and the oscillatory shear index. TBDs provide a handy access to additional information contained in the dynamic structure of the WSS signal as a function of the physiological risk threshold, thereby allowing a quick visual assessment of the risk sensitivity to individual fluctuations of the physiological risk thresholds. Due to its generality, TBD analysis is expected to prove useful for a wide host of applications in science, engineering, and medicine, where risk assessment plays a central role.
authors.affiliation: Nonlinear Physics and Mathematical Modeling Lab, University Campus Bio-Medico, I-00128 Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Gizzi
authors.forename: M
authors.initials: M
authors.lastname: Bernaschi
authors.forename: D
authors.initials: D
authors.lastname: Bini
authors.forename: C
authors.initials: C
authors.lastname: Cherubini
authors.forename: S
authors.initials: S
authors.lastname: Filippi
authors.forename: S
authors.initials: S
authors.lastname: Melchionna
authors.forename: S
authors.initials: S
authors.lastname: Succi
mesh_terms: D000783:Aneurysm / Q000473:pathology; D001783:Blood Flow Velocity; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D009991:Oscillometry / Q000379:methods; D011673:Pulsatile Flow; D012306:Risk; D033081:Shear Strength; D012815:Signal Processing, Computer-Assisted; D013314:Stress, Mechanical; D013997:Time Factors