title: [Colonoscopic screening of asymptomatic individuals with a family history of colorectal cancer].
abstract: OBJECTIVE
  First-degree relatives of colorectal cancer (CRC) patients are at increased risk for developing colorectal neoplasm. The aim of our study was to evaluate the use of total colonoscopy as the screening test in asymptomatic individuals with a family history of colorectal cancer.
  
  
  METHODS
  Colonoscopy was performed in 125 asymptomatic individuals (64 men and 61 women; mean age 51.7 +/- 11.5 years, range 24-77 years) who had one or two first-degree relatives with CRC.
  
  
  RESULTS
  Forty-five colorectal lesions were found in 36 subjects (28.8%): one (0.8%) adenocarcinoma, and 44 polyps (31 adenomas; 13 hiperplasic) (28.0%). The cecum was intubated in 96% of cases, and the procedure was generally well tolerated without complications.
  
  
  CONCLUSIONS
  Total colonoscopy is a useful and safe screening procedure for the examinations of asymptomatic individuals with a family history of CRC.
authors.affiliation: Facultatea de Medicină, Institutul de Gastroenterologie si Hepatologie Iaşi, Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi.
authors.forename: Maria
authors.initials: M
authors.lastname: Maxim
authors.forename: Anca
authors.initials: A
authors.lastname: Trifan
authors.forename: C
authors.initials: C
authors.lastname: Stanciu
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D000236:Adenoma / Q000175:diagnosis; D000328:Adult; D000368:Aged; D003111:Colonic Polyps / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D005192:Family Health; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening; D008487:Medical History Taking; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D011237:Predictive Value of Tests; D015995:Prevalence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012680:Sensitivity and Specificity