title: Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas.
abstract: Infantile hemangioma (IH) is the most common vascular tumor in early childhood. Ulceration is the most frequent complication, and its management can be challenging. We present 6 cases of ulcerated IH at a single pediatric center, which responded to oral propranolol within 2 to 6 weeks. We recommend that oral propranolol therapy be considered for the management of ulcerated IH as first-line treatment.
authors.affiliation: Department of Pediatric Surgery, Sydney Children's Hospital, Randwick, New South Wales, Australia. Electronic address: lawrence.h.c.kim@gmail.com.
authors.forename: Lawrence H C
authors.initials: LHC
authors.lastname: Kim
authors.affiliation: Department of Pediatric Dermatology, Sydney Children's Hospital, Randwick, New South Wales, Australia.
authors.forename: Marcia
authors.initials: M
authors.lastname: Hogeling
authors.affiliation: Department of Pediatric Dermatology, Sydney Children's Hospital, Randwick, New South Wales, Australia.
authors.forename: Orli
authors.initials: O
authors.lastname: Wargon
authors.affiliation: Department of Pediatric Surgery, Sydney Children's Hospital, Randwick, New South Wales, Australia.
authors.forename: Ashish
authors.initials: A
authors.lastname: Jiwane
authors.affiliation: Department of Pediatric Surgery, Sydney Children's Hospital, Randwick, New South Wales, Australia.
authors.forename: Susan
authors.initials: S
authors.lastname: Adams
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D011433:Propranolol / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol