title: Chronic rhinofacial mucormycosis caused by Mucor irregularis (Rhizomucor variabilis) in India.
abstract: In this article, we describe a chronic case of rhinofacial mucormycosis caused by Mucor irregularis, formerly known as Rhizomucor variabilis var. variabilis, a rare mycotic agent in humans. The infection caused progressive destruction of the nasal septum and soft and hard palate, leading to collapse of the nose bridge and an ulcerative gaping hole. The mucoralean mold cultured from a nasal biopsy specimen was determined by multilocus DNA sequence data to be conspecific with M. irregularis.
authors.affiliation: Hi-Tech Health Care and Diagnostic Center, Pvt Ltd, Belgaum 590 002, India.
authors.forename: B M
authors.initials: BM
authors.lastname: Hemashettar
authors.forename: R N
authors.initials: RN
authors.lastname: Patil
authors.forename: Kerry
authors.initials: K
authors.lastname: O'Donnell
authors.forename: Vishnu
authors.initials: V
authors.lastname: Chaturvedi
authors.forename: Ping
authors.initials: P
authors.lastname: Ren
authors.forename: Arvind A
authors.initials: AA
authors.lastname: Padhye
mesh_terms: D000293:Adolescent; D001706:Biopsy; D016000:Cluster Analysis; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics; D020459:Genes, rRNA; D006801:Humans; D007194:India; D008297:Male; D008969:Molecular Sequence Data; D009091:Mucormycosis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D058885:Multilocus Sequence Typing; D016533:Mycological Typing Techniques; D009300:Nasal Septum / Q000473:pathology; D010159:Palate / Q000473:pathology; D020648:Peptide Elongation Factor 1 / Q000235:genetics; D010802:Phylogeny; D012331:RNA, Fungal / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D020103:Rhizomucor / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D012883:Skin Ulcer / Q000473:pathology
chemical_list: D004271:DNA, Fungal; D004275:DNA, Ribosomal; D005656:Fungal Proteins; D020648:Peptide Elongation Factor 1; D012331:RNA, Fungal; D012335:RNA, Ribosomal; D012337:RNA, Ribosomal, 18S; C065096:RNA, ribosomal, 26S