title: Uterine carcinosarcoma.
abstract: Carcinosarcoma is a rare but highly aggressive uterine malignancy. Pathologically, carcinosarcoma is a biphasic neoplasm composed of a mixture of malignant epithelial and mesenchymal components. A comprehensive approach for management is recommended with complete surgical staging to assess tumor dissemination followed by multimodal therapy with combinations of external beam irradiation or vaginal brachytherapy and systematic chemotherapy in patients with both early and advanced stage disease.
authors.affiliation: Division of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Sherif A
authors.initials: SA
authors.lastname: El-Nashar
authors.forename: Andrea
authors.initials: A
authors.lastname: Mariani
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D018714:Radiotherapy, Adjuvant
chemical_list: D000970:Antineoplastic Agents