title: Impact of laparoscopic ovarian drilling on anti-Müllerian hormone levels and ovarian stromal blood flow using three-dimensional power Doppler in women with anovulatory polycystic ovary syndrome.
abstract: OBJECTIVE
  To evaluate the effect of laparoscopic ovarian drilling (LOD) on plasma levels of anti-Müllerian hormone (AMH) and ovarian stromal blood flow changes, by using three-dimensional power Doppler ultrasonography, in polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Prospective controlled study.
  
  
  METHODS
  Taiba hospital, Kuwait.
  
  
  METHODS
  Twenty-three anovulatory clomiphene citrate (CC)-resistant women with PCOS and 20 fertile women as a control group.
  
  
  METHODS
  Laparoscopic ovarian drilling.
  
  
  METHODS
  Serum levels of AMH, ovarian three-dimensional power Doppler indices (vascularization index, flow index, and vascularization flow index) and occurrence of ovulation or pregnancy.
  
  
  RESULTS
  Plasma AMH and power Doppler indices of ovarian stromal blood flow were significantly higher in the PCOS group than in the control group. Plasma AMH and ovarian stromal blood flow Doppler indices were significantly reduced in the PCOS group after LOD. Women who ovulated after LOD had a significantly lower preoperative AMH compared with the nonresponders. There was a significant positive correlation between AMH and power Doppler flow indices before and after LOD in PCOS group.
  
  
  CONCLUSIONS
  Measuring AMH and ovarian stromal three-dimensional power Doppler blood flow for women with anovulatory PCOS undergoing LOD may provide a useful tool in evaluating the outcome of LOD.
authors.affiliation: Department of Obstetrics and Gynecology, Benha Faculty of Medicine, Benha University, Egypt. ashraf_elmashad8@yahoo.com
authors.forename: Ashraf I
authors.initials: AI
authors.lastname: Elmashad
mesh_terms: D000328:Adult; D000858:Anovulation; D054304:Anti-Mullerian Hormone / Q000097:blood*; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D002996:Clomiphene / Q000627:therapeutic use; D004351:Drug Resistance; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D021621:Imaging, Three-Dimensional; D007730:Kuwait; D010535:Laparoscopy; D017078:Laser-Doppler Flowmetry; D010053:Ovary / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism / Q000601:surgery*; D010060:Ovulation; D010062:Ovulation Induction / Q000379:methods*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011247:Pregnancy; D018873:Pregnancy Rate; D012039:Regional Blood Flow; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D005300:Fertility Agents, Female; D002996:Clomiphene; D054304:Anti-Mullerian Hormone