title: Cardiac safety of repetitive transcranial magnetic stimulation in bulimic eating disorders.
abstract: BACKGROUND
  Repetitive transcranial magnetic stimulation (rTMS) is increasingly used in research. However, cardiac safety is not routinely assessed.
  
  
  OBJECTIVE
  This study aims to investigate cardiac safety of rTMS in people with a bulimic eating disorder.
  
  
  METHODS
  Thirty-eight people with a bulimic disorder were enrolled in a randomized sham-controlled trial. High frequency rTMS was delivered to the left dorsolateral prefrontal cortex.
  
  
  RESULTS
  rTMS did not alter blood pressure or heart rate.
  
  
  CONCLUSIONS
  Our findings indicated that this rTMS paradigm has no cardiac complications as assessed by blood pressure and heart rate. This adds to the emerging literature on the cardiac safety of rTMS.
authors.affiliation: Institute of Psychiatry, King's College London, London, United Kingdom. Frederique.vandeneynde@iop.kcl.ac.uk
authors.forename: Frederique
authors.initials: F
authors.lastname: Van den Eynde
authors.forename: Angélica M
authors.initials: AM
authors.lastname: Claudino
authors.forename: Iain
authors.initials: I
authors.lastname: Campbell
authors.forename: Linda
authors.initials: L
authors.lastname: Horrell
authors.forename: Manoharan
authors.initials: M
authors.lastname: Andiappan
authors.forename: Daniel
authors.initials: D
authors.lastname: Stahl
authors.forename: Ulrike
authors.initials: U
authors.lastname: Schmidt
mesh_terms: D001794:Blood Pressure / Q000528:radiation effects; D002032:Bulimia / Q000628:therapy*; D004311:Double-Blind Method; D006321:Heart / Q000528:radiation effects*; D006339:Heart Rate / Q000528:radiation effects; D006801:Humans; D008297:Male; D012449:Safety; D050781:Transcranial Magnetic Stimulation / Q000009:adverse effects*