title: Pediatric otogenic lateral sinus thrombosis recanalization.
abstract: OBJECTIVE
  To describe the recovery outcomes in pediatric patients with otogenic lateral sinus and internal jugular vein thrombosis.
  
  
  METHODS
  An inpatient database from a tertiary care pediatric hospital was queried from 1999 to 2010 for the diagnosis code [325] thrombosis of intracranial venous sinus. Demographics, extent of thrombosis, surgical intervention, use of anticoagulation, and the presence of recanalization on follow-up imaging was collected.
  
  
  RESULTS
  Fifteen patients (10 male, 5 female) were identified with otogenic lateral sinus thrombosis. Eleven patients (73.3%) had evidence of thrombus in the transverse sinus, while 10 patients (66.7%) had thrombus in the internal jugular vein, and one patient (6.7%) had thrombus in the cavernous sinus. Five patients (33%) had otitic hydrocephalus. Twelve patients (80%) underwent operative manipulation of the lateral sinus including: three decompressions 20%, three needle aspirations 20%, and six venotomies with evacuation of clot or pus 40%. Twelve patients were anticoagulated with low molecular weight heparin, and three patients were not anticoagulated. Ten of fourteen patients (71.4%) who underwent follow-up magnetic resonance venography had evidence of partial (57.1%) or complete (14.3%) recanalization of the lateral sinus. All five patients with otitic hydrocephalus recovered as determined by a normal fundoscopic exam and recovery of abducens paresis.
  
  
  CONCLUSIONS
  Recanalization of the lateral intracranial venous sinus occurred in the majority of the patients in this series. The role of operative intervention and/or anticoagulation remains unclear.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390-9035, USA.
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Neilan
authors.forename: Brandon
authors.initials: B
authors.lastname: Isaacson
authors.forename: J Walter
authors.initials: JW
authors.lastname: Kutz
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Lee
authors.forename: Peter S
authors.initials: PS
authors.lastname: Roland
mesh_terms: D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D007223:Infant; D007601:Jugular Veins; D020227:Lateral Sinus Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D007902:Length of Stay; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D000925:Anticoagulants