title: Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients.
abstract: OBJECTIVE
  Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population.
  
  
  METHODS
  Forty-eight consecutive young patients admitted for acute ischemic stroke participated in the study. First-line screening was performed, including blood tests, cardiovascular investigations, and urine analysis for cannabinoids. If no etiology was found, 3D rotational angiography and cerebrospinal fluid analysis were performed. A control was planned through neurovascular imaging within 3 to 6 months.
  
  
  RESULTS
  In this series, there was multifocal intracranial stenosis associated with cannabis use in 21% (n=10).
  
  
  CONCLUSIONS
  Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people.
authors.affiliation: Unite´ Neuro-Vasculaire, Hôpitaux Universitaires de Strasbourg, France. valerie.wolff@chru-strasbourg.fr
authors.forename: Valérie
authors.initials: V
authors.lastname: Wolff
authors.forename: Valérie
authors.initials: V
authors.lastname: Lauer
authors.forename: Olivier
authors.initials: O
authors.lastname: Rouyer
authors.forename: François
authors.initials: F
authors.lastname: Sellal
authors.forename: Nicolas
authors.initials: N
authors.lastname: Meyer
authors.forename: Jean Sébastien
authors.initials: JS
authors.lastname: Raul
authors.forename: Cécile
authors.initials: C
authors.lastname: Sabourdy
authors.forename: Fazel
authors.initials: F
authors.lastname: Boujan
authors.forename: Christine
authors.initials: C
authors.lastname: Jahn
authors.forename: Rémy
authors.initials: R
authors.lastname: Beaujeux
authors.forename: Christian
authors.initials: C
authors.lastname: Marescaux
mesh_terms: D000328:Adult; D001808:Blood Vessels / Q000187:drug effects / Q000473:pathology; D002545:Brain Ischemia / Q000209:etiology*; D002188:Cannabis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020521:Stroke / Q000209:etiology*; D014661:Vasoconstriction / Q000187:drug effects*