title: Metachronous occurrence of a temporal ganglioglioma and a bifrontal anaplastic ependymoma: coincidence or an explainable pathological curiosity?
abstract: In this first-of-its-kind report, we describe an unusual case of a 32-year-old man who harboured two biologically distinct metachronous brain tumours. He presented with features of raised intracranial pressure 8 years after total excision of a right temporal ganglioglioma. Imaging showed a heterogenously contrast enhancing bifrontal lesion with ventricular extension. Histopathological examination revealed an anaplastic ependymoma. While a co-incidental occurrence is a possibility, there could be possible mechanisms to explain this pathological oddity.
authors.affiliation: Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bangalore 560066, India. sumit.thakar@gmail.com
authors.forename: Sumit
authors.initials: S
authors.lastname: Thakar
authors.forename: Vani
authors.initials: V
authors.lastname: Santosh
authors.forename: Nandita
authors.initials: N
authors.lastname: Ghosal
authors.forename: Sunil V
authors.initials: SV
authors.lastname: Furtado
authors.forename: Alangar S
authors.initials: AS
authors.lastname: Hegde
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D004806:Ependymoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005625:Frontal Lobe; D018303:Ganglioglioma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D019586:Intracranial Hypertension / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013702:Temporal Lobe; D055815:Young Adult