title: Multicentric infantile hemangiopericytoma: case report and review of the literature.
abstract: Hemangiopericytomas are rare tumors in which outcome varies with age of onset. Those developing in adults and older children tend to be aggressive with a poor prognosis. However, infantile hemangiopericytomas often behave in a more benign manner. Recent findings suggest aggressive lesions may be histogenetically distinct. Multicentric disease is exceptionally rare, but tends to occur in infants and poses a therapeutic challenge. We present a case with extensive cutaneous and intracranial involvement, which resolved spontaneously. Tumor behavior is a key consideration in management, with careful observation recommended in uncomplicated cases and intervention indicated if more aggressive growth or spread occurs.
authors.affiliation: Dermatology Department, Naval Medical Center, San Diego, CA, USA.
authors.forename: Daryl J
authors.initials: DJ
authors.lastname: Sulit
authors.forename: Wynnis L
authors.initials: WL
authors.lastname: Tom
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Willert
authors.forename: Mark P
authors.initials: MP
authors.lastname: Nespeca
authors.forename: Sheila Fallon
authors.initials: SF
authors.lastname: Friedlander
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis*; D002648:Child; D006393:Hemangiopericytoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D012075:Remission, Spontaneous; D012878:Skin Neoplasms / Q000175:diagnosis*