title: One-pot synthesis of 1,2,3-triazole linked dihydropyrimidinones via Huisgen 1,3-dipolar/Biginelli cycloaddition.
abstract: The combination of the Biginelli reaction with click chemistry has been used for the one-pot synthesis of 1,2,3-triazole linked dihydropyrimidinones from azides, aromatic aldehydes containing a propargyl ether group, urea, and 1,3-dicarbonyl compounds using Cu(OAc)(2)/sodium ascorbate as catalyst in acetic acid under mild reaction conditions.
authors.affiliation: Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G C, Evin, 1983963113 Tehran, Iran. p-salehi@sbu.ac.ir
authors.forename: Peyman
authors.initials: P
authors.lastname: Salehi
authors.forename: Minoo
authors.initials: M
authors.lastname: Dabiri
authors.forename: Majid
authors.initials: M
authors.lastname: Koohshari
authors.forename: Siyavash Kazemi
authors.initials: SK
authors.lastname: Movahed
authors.forename: Morteza
authors.initials: M
authors.lastname: Bararjanian
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D003300:Copper / Q000737:chemistry; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D011744:Pyrimidinones; D014230:Triazoles; D003300:Copper