title: Oogenesis: when most is good enough.
abstract: In male meiosis an unaligned chromosome blocks meiotic progression. However, oocytes with one or more misaligned chromosomes can complete meiosis. This difference reflects a more permissive role of the spindle assembly checkpoint, rather than solely reflecting the ability of some univalents to adopt a meiosis II-like orientation on the spindle.
authors.affiliation: Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA. rsh@stowers.org
authors.forename: R Scott
authors.initials: RS
authors.lastname: Hawley
mesh_terms: D000818:Animals; D016922:Cellular Senescence; D020090:Chromosome Segregation; D033481:Chromosomes, Mammalian / Q000235:genetics / Q000378:metabolism; D005260:Female; D018386:Kinetochores / Q000378:metabolism; D008540:Meiosis; D009865:Oocytes / Q000166:cytology* / Q000378:metabolism; D009866:Oogenesis; D008941:Spindle Apparatus / Q000378:metabolism*