title: MDCT evaluation of cardiac involvement in hypereosinophilic syndrome: differentiating mural thrombus, infarcted, and noninfarcted myocardium by delayed-phase scanning.
abstract: Hypereosinophilic syndrome is a rare disease that can cause multiple-organ damage. Cardiac involvement, which presents as myocardial necrosis, infarction, or thrombus formation, is the leading cause of morbidity and death. Here, we present the case of a 17-year-old girl who had hypereosinophilic syndrome with cardiac involvement, which was evaluated by multidetector-row computed tomography. By means of arterial-phase and low-dose delayed-phase scanning, multidetector-row computed tomography clearly identified the mural thrombus and the infarcted and noninfarcted myocardium-which surpassed the performance of echocardiography in tissue characterization. Therefore, we propose that multidetector-row computed tomography could be a useful noninvasive tool for evaluating patients with cardiac involvement of hypereosinophilic syndrome.
authors.affiliation: Faculty of Medicine, Taipei Medical University, Taipei 110, Republic of China.
authors.forename: Chuan-Han
authors.initials: CH
authors.lastname: Chen
authors.forename: I-Chen
authors.initials: IC
authors.lastname: Tsai
authors.forename: Sheng-Ling
authors.initials: SL
authors.lastname: Jan
authors.forename: Wei-Lin
authors.initials: WL
authors.lastname: Tsai
authors.forename: Clayton Chi-Chang
authors.initials: CC
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001856:Bone Marrow Examination; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000209:etiology; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis; D011237:Predictive Value of Tests; D013927:Thrombosis / Q000000981:diagnostic imaging* / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography