title: Optically pure polyfluoroalkanesulfinamides: synthesis and application as promising and monitorable chiral auxiliaries.
abstract: Efficient synthesis of enantiopure polyfluoroalkanesulfinamides (PFSAs) has been achieved. Their application as novel chiral auxiliaries with an electron-withdrawing and (19)F NMR monitorable polyfluoroalkyl group was initially demonstrated in an asymmetric Strecker reaction under mild conditions.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Liu
authors.forename: Ling-Jun
authors.initials: LJ
authors.lastname: Chen
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Li
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Liu
mesh_terms: D055620:Optical Phenomena; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D013452:Sulfonium Compounds