title: Effect of human leukocyte antigen class II genes on insulin deficiency in slow-onset type 1 diabetes in the Japanese population.
abstract: The aim of this study is to determine the contribution of human leukocyte antigen (HLA) class II genes to insulin deficiency in slow-onset type 1 diabetes (T1D). Our results suggest that the susceptibility conferred by HLA subtypes to slow-onset T1D differs between insulin-deficient patients and non-insulin-deficient patients.
authors.affiliation: Department of Endocrinology and Diabetes, Ichinomiya Municipal Hospital, 2-2-22 Bunkyo, Ichinomiya, Aichi 491-8558, Japan. katahira-0034@umin.net
authors.forename: Masahito
authors.initials: M
authors.lastname: Katahira
authors.forename: Mizuki
authors.initials: M
authors.lastname: Hanakita
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yasuda
authors.forename: Harumi
authors.initials: H
authors.lastname: Maeda
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Ito
authors.forename: Satoko
authors.initials: S
authors.lastname: Segawa
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D044466:Asian People; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006683:HLA-DQ Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006239:Haplotypes; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D007328:Insulin / Q000172:deficiency*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D007328:Insulin