title: [Results of nephrectomy for native kidney tumors in renal transplanted patients].
abstract: OBJECTIVE
  Evaluate epidemiology, diagnosis and outcome of de novo renal cell carcinoma in renal transplanted patients.
  
  
  METHODS
  From June 1989 to December 2007, 824 renal transplantations were carried out and followed in annual consultation by an urologist with abdominal echography or tomodensitometry. The suspect renal lesions were treated by a widened nephrectomy. Incidence, diagnosis, treatment, histological type, and outcome of all patients were analysed.
  
  
  RESULTS
  Thirty-three patients had nephrectomy for suspect renal lesions. Twenty-two de novo tumours of native kidneys among 21 patients were diagnosed (15 renal clear cell carcinoma and seven papillary tumours) with mean time after transplantation of 25,6 months (2.3-105.5). All tumours were classified pT1aN0M0. Only one patient died at 8 months of metastatic dissemination of a papillary tumour classified initially pT1aN0M0. All the other patients are alive with mean follow-up of 34.8 months (2.8-113.9). Specific survival to 5 years was 93.3%.
  
  
  CONCLUSIONS
  The increase risk of tumour at the renal transplanted patient led to propose in the event of suspect lesions of the native kidneys, a widened nephrectomy. In our series, 65% of the operated patients carried a cancer. The good forecast of these localized tumours justifies a regular radiological monitoring and an aggressive therapeutic attitude despite of absence of tumours in 35% of the transplanted patients.
authors.affiliation: Service d'urologie et transplantation rénale, CHU Sud, avenue Laennec, 80000 Amiens, France. xavtillou@hotmail.com
authors.forename: X
authors.initials: X
authors.lastname: Tillou
authors.forename: L
authors.initials: L
authors.lastname: Viart
authors.forename: M
authors.initials: M
authors.lastname: Demailly
authors.forename: F
authors.initials: F
authors.lastname: Hakami
authors.forename: P-F
authors.initials: PF
authors.lastname: Westeel
authors.forename: F
authors.initials: F
authors.lastname: Saint
authors.forename: J
authors.initials: J
authors.lastname: Petit
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011183:Postoperative Complications / Q000601:surgery*; D012189:Retrospective Studies