title: Pin-pointing a new DAP kinase function: the peptidyl-proly isomerase Pin1 Is Negatively Regulated by DAP kinase-mediated phosphorylation.
abstract: In this issue of Molecular Cell, Lee et al. (2011) identify the peptidyl-prolyl isomerase Pin1 as a substrate of DAP kinase, simultaneously providing a critical regulatory mechanism for Pin1 inhibition and a potential mechanism that accounts for DAPK's tumor-suppressive activities.
authors.affiliation: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
authors.forename: Shani
authors.initials: S
authors.lastname: Bialik
authors.forename: Adi
authors.initials: A
authors.lastname: Kimchi