title: [Value of deep small-bowel endoscopy in the diagnosis of Crohn's disease].
abstract: OBJECTIVE
  To evaluate the value of deep small-bowel endoscopy (DSBE) in the diagnosis of Crohns disease (CD).
  
  
  METHODS
  The endoscopic and clinical data of 54 patients with CD receiving capsule endoscopy (CE) and double-balloon enteroscopy (DBE) between January, 2004 and December, 2008 were summarized and analyzed retrospectively.
  
  
  RESULTS
  The main indications for DSBE in our series were suspected CD (42.6%) and obscure gastrointestinal bleeding (25.9%). DSBE was obviously superior to barium imaging. The detection rate of CD was significantly higher with DSBE (92.6%) than with ileocolonoscopy (75.9%, P=0.017), and DSBE provides much more detailed descriptions of specific endoscopic features such as segmental distribution and lumen changes. DSBE significantly improve the diagnostic efficiency, giving priority to offer a guide and raise suspected diagnosis for CD.
  
  
  CONCLUSIONS
  DSBE is a valuable modality for detecting CD lesions in the jejunum and ileum and for evaluating lesion involvement and severity. The combination with a comprehensive analysis of routine imaging findings, gastro endoscopy, and clinical data can further enhance the diagnostic efficiency of DSBE.
authors.affiliation: Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. zshiny2008@sina.com
authors.forename: Shao-Heng
authors.initials: SH
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Qing
authors.initials: Q
authors.lastname: Qing
authors.forename: Fa-Chao
authors.initials: FC
authors.lastname: Zhi
authors.forename: Yang
authors.initials: Y
authors.lastname: Bai
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Zhang
authors.forename: Ye
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D053704:Capsule Endoscopy; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology*; D058582:Double-Balloon Enteroscopy; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies; D055815:Young Adult