title: Posterior chamber collagen copolymer phakic intraocular lenses to correct myopia: five-year follow-up.
abstract: OBJECTIVE
  To evaluate the long-term safety and efficacy of posterior chamber collagen copolymer phakic intraocular lens (pIOL) implantation to correct myopia.
  
  
  METHODS
  Fernández-Vega Ophthalmological Institute, Oviedo, Spain.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, pIOL vault, endothelial cell loss, and adverse events were evaluated for 5 years after implantation of the Visian Implantable Collamer Lens pIOL for moderate to high myopia.
  
  
  RESULTS
  The mean spherical equivalent (188 eyes) decreased from -11.17 diopters (D) ± 3.40 (SD) preoperatively to -0.88 ± 0.72 D 5 years postoperatively. The mean change in refraction from 1 month to 5 years was -0.65 ± 0.65 D. The mean UDVA and CDVA (Snellen decimal) were 0.69 ± 0.26 and 0.83 ± 0.15, respectively. The mean safety and efficacy indices were 1.27 ± 0.33 and 0.89 ± 0.35, respectively. No eye lost more than 2 lines of visual acuity; 70% achieved 0.80 or better CDVA. Three eyes (1.6%) developed late anterior subcapsular cataract that was clinically significant in 1 case, leading to pIOL removal and phacoemulsification. Of the 3 eyes (1.6%) with a mild transient increase in intraocular pressure (up to 27 mm Hg), none required a second surgical procedure or prolonged topical medication. The total endothelial cell loss (considered cumulatively at consecutive intervals through 5 years) was 7.7%. There was a tendency toward decreased pIOL vault decrease over time. No vision-threatening complications occurred.
  
  
  CONCLUSIONS
  Implantation of the collagen copolymer pIOL for moderate to high myopia was safe and effective and provided long-term predictable, stable refractive results.
authors.affiliation: Fernández-Vega Ophthalmological Institute, Avenida Doctores Fernández-Vega 114, 33012, Oviedo, Spain. j.alfonso@fernandez-vega.com
authors.forename: José F
authors.initials: JF
authors.lastname: Alfonso
authors.forename: Begoña
authors.initials: B
authors.lastname: Baamonde
authors.forename: Luis
authors.initials: L
authors.lastname: Fernández-Vega
authors.forename: Paulo
authors.initials: P
authors.lastname: Fernandes
authors.forename: Jose M
authors.initials: JM
authors.lastname: González-Méijome
authors.forename: Robert
authors.initials: R
authors.lastname: Montés-Micó
mesh_terms: D000328:Adult; D003094:Collagen; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011108:Polymers; D057972:Posterior Eye Segment / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
chemical_list: D011108:Polymers; D003094:Collagen