title: [Verapamil-induced linear IgA disease mimicking toxic epidermal necrolysis].
abstract: BACKGROUND
  Linear IgA bullous dermatosis is a rare auto-immune bullous dermatitis characterized by linear IgA deposits in the basal membrane zone. Clinical diagnosis may be difficult due to the various clinical presentations mimicking bullous pemphigoid, pemphigus, erythema multiforme or toxic epidermal necrolysis. Linear IgA may be idiopathic or due to drugs, particularly vancomycin.
  
  
  METHODS
  We describe a 91-year-old woman treated with verapamil for coronary disease who developed an eruption presenting as a toxic epidermal necrolysis, although the diagnosis was amended after direct immunofluorescence revealed IgA deposits in the basal membrane zone.
  
  
  CONCLUSIONS
  Ours appears to be the first reported case of verapamil-induced linear IgA bullous dermatosis.
authors.affiliation: Service de dermatologie, hôpital Victor-Dupouy, Argenteuil, France.
authors.forename: D
authors.initials: D
authors.lastname: Schroeder
authors.forename: D
authors.initials: D
authors.lastname: Saada
authors.forename: M
authors.initials: M
authors.lastname: Rafaa
authors.forename: S
authors.initials: S
authors.lastname: Ingen-Housz-Oro
authors.forename: L
authors.initials: L
authors.lastname: Valeyrie-Allanore
authors.forename: M-L
authors.initials: ML
authors.lastname: Sigal
mesh_terms: D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy*; D001327:Autoimmune Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D002121:Calcium Channel Blockers / Q000627:therapeutic use / Q000633:toxicity*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D008856:Microscopy, Fluorescence; D012867:Skin / Q000187:drug effects / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis* / Q000473:pathology; D014700:Verapamil / Q000627:therapeutic use / Q000633:toxicity*
chemical_list: D002121:Calcium Channel Blockers; D007070:Immunoglobulin A; D014700:Verapamil