title: Focus issue: moving in the right direction.
abstract: Cells interpret environmental cues to extend processes in the appropriate direction, descend upon sources of inflammation or necrosis, or determine the best path to the correct position in a developing organism. This Focus Issue of Science Signaling highlights the signaling pathways and mechanisms that enable cells to sense external signals and direct their movement accordingly.
authors.forename: Wei
authors.initials: W
authors.lastname: Wong
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology; D002633:Chemotaxis / Q000502:physiology; D006801:Humans; D016023:Integrins / Q000502:physiology; D009369:Neoplasms / Q000473:pathology / Q000503:physiopathology; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D016023:Integrins