title: [Risk factors for Pseudomonas aeruginosa infections, resistant to carbapenem].
abstract: Since their introduction in clinical practice,carbapenems have been among the most powerful antibiotics for treating serious infections cased by Gram-negative nosocomial pathogens, including Pseudomonas aeruginosa. The emergence of betalactamases with carbapenem-hydrolyzing activity is of major clinical concern. Pseudomonas aeruginosa is a leading cause of nosocomial infection.
  
  
  RESULTS
  Risk factors for colonization with carbapenems-resistant Pseudomonas in hospital are: history of P. aeruginosa infection or colonization within the previous year, (length of hospital stay, being bedridden or in the ICU, mechanical ventilation, malignant disease, and history of chronic obstructive pulmonary disease have all been identified as independent risk factors for MDR P. aeruginosa infection. Long-term-care facilities are also reservoirs of resistant bacteria. Risk factors for colonization of LTCF residents with resistant bacteria included age > 86 years, antibiotic treatment in the previous 3 months, indwelling devices, chronic obstructive pulmonary disease, physical disability, and the particular LTCF unit.
authors.affiliation: Facultatea de Medicină, Clinica de Boli Infecţioase, Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi.
authors.forename: Laura
authors.initials: L
authors.lastname: Ghibu
authors.forename: Egidia
authors.initials: E
authors.lastname: Miftode
authors.forename: Andra
authors.initials: A
authors.lastname: Teodor
authors.forename: Codrina
authors.initials: C
authors.lastname: Bejan
authors.forename: Carmen Mihaela
authors.initials: CM
authors.lastname: Dorobăţ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015780:Carbapenems / Q000494:pharmacology* / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012189:Retrospective Studies; D012307:Risk Factors; D018440:beta-Lactam Resistance
chemical_list: D015780:Carbapenems