title: Inhaled iloprost for therapy in pulmonary arterial hypertension.
abstract: Iloprost (Ventavis, Bayer Schering Pharma, Germany) is a synthetic prostacyclin that is used in its inhalative form for the therapy of pulmonary arterial hypertension. Long-term therapy can increase exercise capacity and quality of life. The use of modern nebulizers especially designed for the administration of iloprost guarantees the pulmonary deposition of the required doses and systematically minimizes side effects. Regarding existing data, inhalative iloprost acts in effective and safe combination with other classes of medication; indeed, such combination therapy is frequently necessary in pulmonary arterial hypertension.
authors.affiliation: Department of Internal Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.
authors.forename: Ralf
authors.initials: R
authors.lastname: Ewert
authors.forename: Sven
authors.initials: S
authors.lastname: Gläser
authors.forename: Tom
authors.initials: T
authors.lastname: Bollmann
authors.forename: Christoph
authors.initials: C
authors.lastname: Schäper
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D065627:Familial Primary Pulmonary Hypertension; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000503:physiopathology; D016285:Iloprost / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D009330:Nebulizers and Vaporizers; D018570:Risk Assessment; D016896:Treatment Outcome; D014664:Vasodilation / Q000187:drug effects; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics
chemical_list: D000959:Antihypertensive Agents; D014665:Vasodilator Agents; D016285:Iloprost