title: 2-(Furan-2-yl)-5-(2-nitro-benz-yl)-2,3-dihydro-1,5-benzothia-zepin-4(5H)-one.
abstract: The title compound, C(20)H(16)N(2)O(4)S, was prepared by introduction of a 2-nitro-benzyl group to 2-(furan-2-yl)-2,3-dihydro-1,5-benzothia-zepin-4(5H)-one via an alkaline-catalysed reaction. The thia-zepine ring adopts a twist-boat conformation. The furan ring is oriented at dihedral angles of 56.75 (14) and 10.82 (14)° with respect to the two benzene rings, while the two benzene rings make a dihedral angle of 62.96 (10)°. Weak inter-molecular C-H⋯O hydrogen bonds occur in the crystal structure.
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, People's Republic of China.
authors.forename: Zhao-Hui
authors.initials: ZH
authors.lastname: Huang
authors.forename: Yong
authors.initials: Y
authors.lastname: Chu
authors.forename: De-Yong
authors.initials: DY
authors.lastname: Ye