title: Corneal chromoblastomycosis caused by Cladophialophora carrionii after cataract surgery.
abstract: We describe a case of corneal chromoblastomycosis with Cladophialophora carrionii in a 69-year-old woman 4 weeks after clear corneal cataract surgery. The patient presented with right eye pain and decreased visual acuity of 20/100. Examination showed a deep posterior stromal keratitis accompanied by a dense fibrinous anterior chamber reaction. An aqueous tap was performed, and the patient was treated with topical, systemic, and intracameral antifungal and antibiotic agents. The infection was resistant to medical therapy and the course further complicated by secondary pupillary block glaucoma. After 10 days, a therapeutic penetrating keratoplasty was performed. The patient remained asymptomatic 20 months after the initial presentation, with corrected distance visual acuity restored to 20/40. To our knowledge, is the first reported case of corneal chromoblastomycosis with C carrionii. Early surgical treatment may be necessary to eradicate Cladophialophora species.
authors.affiliation: Institute of Ophthalmology and Visual Science, UMDNJ-New Jersey Medical School, Doctors Office Center, Suite 6100, PO Box 1709, Newark, New Jersey 07101-1709, USA. hamed_lari@yahoo.com
authors.forename: Hamed Bazargan
authors.initials: HB
authors.lastname: Lari
authors.forename: Neena
authors.initials: N
authors.lastname: Mirani
authors.forename: David S
authors.initials: DS
authors.lastname: Chu
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage; D002862:Chromoblastomycosis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D002963:Cladosporium / Q000302:isolation & purification*; D003320:Corneal Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery
chemical_list: D000935:Antifungal Agents